LOCUS       DBEJHE010000001       143804 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC4 isolate 671759
            SAMN38261586-rid24793303.denovo.01, whole genome shotgun sequence.
ACCESSION   DBEJHE010000001 DBEJHE010000000
VERSION     DBEJHE010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261586
            Sequence Read Archive: SRR26833752
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 143804)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 143804)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576136.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576136.1
            Genome Coverage       :: 109x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 19:48:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,067
            CDSs (total)                      :: 2,029
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 131
            CDSs (without protein)            :: 131
            Pseudo Genes (ambiguous residues) :: 0 of 131
            Pseudo Genes (frameshifted)       :: 64 of 131
            Pseudo Genes (incomplete)         :: 59 of 131
            Pseudo Genes (internal stop)      :: 46 of 131
            Pseudo Genes (multiple problems)  :: 32 of 131
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..143804
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261586-rid24793303.denovo.01"
                     /strain="GPSC4"
                     /isolate="671759"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            100..1575
                     /locus_tag="ACL3EZ_000001"
     CDS             100..1575
                     /locus_tag="ACL3EZ_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HGR0391659.1"
                     /translation="MDAIFDLIGKVFNPILEMGGPVIMLIILTVLALLFGVKFSKALE
                     GGIKLAIALTGIGAIIGMLNGAFSASLAKFVENTGIQLSITDVGWAPLATITWGSAWT
                     LYFLLIMLIVNVVMLAMKKTDTLDVDIFDIWHLSITGLLIKWYADNNGVSQGVSLFIA
                     TAAIVLVGVLKIINSDLMKPTFDDLLNAPSSSPMTSTHMNYMMNPVIMVLDKIFEKFF
                     PGLDKYDFDAAKLNKKIGFWGSKFFIGFILGIVIGIMGTPHPIAGVADADKWRLVIKG
                     WLSLGLTAGVSLELFSLIGSWFIAAVEPLSQGITNVATKRLRGRKFNIGLDWPFIAGR
                     AEIWACANVLAPIMLIEAVLLSKVGNGILPLAGIIAMGVTPALLVVTRGKLLRMIIFG
                     TLLLPLFLLSGTLIAPFATELAKGVGAFPEGVSQTQLITHSTLEGPIEKLLGWTIGNT
                     TTGDIKAILGAVVFLVFYIGIFAWYRKQMIKRNEEYAAKAK"
     gene            1880..8581
                     /gene="bgaA"
                     /locus_tag="ACL3EZ_000002"
     CDS             1880..8581
                     /gene="bgaA"
                     /locus_tag="ACL3EZ_000002"
                     /EC_number="3.2.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000515226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored adhesin/beta-galactosidase BgaA"
                     /protein_id="HGR0391660.1"
                     /translation="MGKGHWNRKRVYSIRKFAVGACSVMIGTCAVLLGGNIAGESVVY
                     ADETLITHTAEKPKEEKMIVEEKADKALETKNVVERTEQSEPSSTEAIASEKKEDEAV
                     TPKEEKVSAKPEEKAPRIESQASSQEKPLKEDAKAVTNEEMNQMIEDRKVDFNQNWHF
                     KLNANSKEAIKPDADVSTWKKLDLPYDWSIFNNFDHESPAQNEGGQLNGGEAWYRKTF
                     KLDEKDLKKNVRLTFDGVYMDSQVYVNGQLVGHYPNGYNQFSYDITKYLHKDGRENVI
                     AVHAVNKQPSSRWYSGSGIYRDVTLQVTDKVHVEKNGTTILTPKLEEQQHGKVETHVT
                     SKIVNTDDKDHELVAEYQIVERGGRAVTGLVRTASRTLKAHESTSLDAILEVERPKLW
                     TVLNDKPALYELITRVYRDGQLVDAKKDLFGYRYYHWTPNEGFSLNGERIKFHGVSLH
                     HDHGALGAEENYKAEYRRLKQMKEMGVNSIRTTHNPASEQTLQIAAELGLLVQEEAFD
                     TWYGGKKPYDYGRFFEKDATHPEARKGEKWSDFDLRTMVERGKNNPAIFMWSIGNEIG
                     EANGDAHSLATVKRLVKVIKDVDKTRYVTMGADKFRFGNGSGGHEKIADELDAVGFNY
                     SEDNYKALRAKHPKWLIYGSETSSATRTRGSYYRPERELKHSNGPERNYEQSDYGNDR
                     VGWGKTATASWTFDRDNAGYAGQFIWTGTDYIGEPTPWHNQNQTPVKSSYFGIVDTAG
                     IPKHDFYLYQSQWVSVKKKPMVHLLPHWNWENKELASKVADSEGKIPVRAYSNASSVE
                     LFLNGKSLGLKTFNKKQTSDGRTYQEGANANELYLEWKVAYQPGTLEAIARDESGKEI
                     ARDKITTAGKPAAVRLIKEDHAIAADGKDLTYIYYEIVDSQGNVVPTANNLVRFQLHG
                     QGQLVGVDNGEQASRERYKAQADGSWIRKAFNGKGVAIVKSTEQAGKFTLTAHSDLLK
                     SSQVTVFTGKKEGQEKTVLGTEVPKVQTIIGEAPEMPTTVPFLYSDGSRAERPVTWSS
                     VDVSKPGIVTVKGMADGREVEARVEVIALKSELPVVKRIAPNTDLNSVDKSVSYVLTD
                     GSVQEYEVDSWEITEVDKAKLSVAGSRIQMTGQLAGETIHATLVVEEGNAAAPVVPTV
                     TVGGEAVTGLTSRQPMQYRTLSYGAQLPEVTASAENADVTVLQASAANGMRASIFVQP
                     KDGGPLQTYAIQFLEEAPKIAHLSLQVEKADSLKEDQTVKLSVRAHYQDGTQAVLPAD
                     KVTFSTSGEGEVAIRKGMLELHKPGAVTLKAEYEGAKGQVELTIQANTEKKIAQSIRP
                     VNVVTDLHQKPTLPTTVTVEYDKGFPKAHKVTWQAIPKEKLDSYQTFEVLGKVEGIDL
                     EARAKVSVEGIVSVEEVSVTTPIAEAPQLPESVRTYDSNGHVSSAKVAWDAIRPEQYA
                     KEGVFTVNGRLEGTQLTTKLHVRVSAQTEQGANISDQWTGSELPLAFASDSNPSDPVS
                     NVNDKLISYNNQPANRWTNWNRTNPEASVGVLFGDSGILSKRSVDNLSVGFHEDHGVG
                     APKSYVIEYYVGKTVPTAPKNPSFVGNEDHVFNDSANWKPVTNLKAPAQLKAGEMNHF
                     SFDKVETYAVRIRMVRADNKLGTSITEVQIFAKQVAAAKQGQTRIQVDGKDLANFNPD
                     LTDYYLESVDGKVTAVTASVSNNGLATVVPSVREGEPVRVIAKAENGDILGEYRLHFT
                     KDKNLLSHKPVAAVKQARLLQVGQALELPTKVPVYFTGKDGYETKNLTVEWEEVPAEN
                     LIKAGQFTVRGHVLGSDLVAEVTVRVTDKLGEALSDNPNYDENSNQAFASATNDIDKN
                     SHDRVDYLNDGDHSENRRWTNWSPTPSSNPEVSAGVIFRENGKIVERTVAQAKLHFFA
                     DSGTDAPTKLVLERYVGPEFEVPTYYSNYQAYDADHPFNNPENWEAVPYRADKDIAAG
                     DEINVTFKAVKAKAMRWRMERKADKSGVAMIEMTFLAPSELPQESTQSKILVDGKELA
                     DFAENRQDYQITYKGQRPKVSVEENNQVASTVVDSGEDSLPVLVRLVSESGKQVKEYR
                     IQLTKEKPVSEKTVAAVQEDLPKLEFVEKDLAYKTVEKKDSTLYLGETRVEQEGKTGK
                     ERIFTAINPDGSKEEKLREVVEAPTDRIVLVGTKPVAQEAKKPQVSEKADTKPIDSSE
                     ASQTNKAQLPNTGSAASQAAVAAGLALLGLSAGLVVTKGKKED"
     gene            complement(8829..9275)
                     /locus_tag="ACL3EZ_000003"
     CDS             complement(8829..9275)
                     /locus_tag="ACL3EZ_000003"
                     /inference="COORDINATES: protein motif:HMM:NF013752.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGR0391661.1"
                     /translation="MFDKEQKRGYKQSAKNLANWHYNDKEDSYIHPDGWCYRFHHIKY
                     QKTQTDFQQEIKVYYADEPESAPQKGLYMNERYQNLKAKECQALLSPQDRQIFAQRKI
                     DVEPVFGQIKACLGYKRCNLRGKRQVRIDMGLVLMANNLLKHSEMK"
     gene            complement(9440..9685)
                     /locus_tag="ACL3EZ_000004"
     CDS             complement(9440..9685)
                     /locus_tag="ACL3EZ_000004"
                     /inference="COORDINATES: protein motif:HMM:NF017416.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGR0391662.1"
                     /translation="MHIHYNTNQTTLPLEISSFLPQDHLVFTIEKVVNTLEERHFYTS
                     YHAFGRPSYHPKMLVSTLLFAYSQGIFSGRKIEKWKS"
     gene            complement(9896..10255)
                     /locus_tag="ACL3EZ_000005"
     CDS             complement(9896..10255)
                     /locus_tag="ACL3EZ_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HGR0391663.1"
                     /translation="MGMILMKLASILLLILTLVVCIILTKLFRLKKLGRNFADLAFPV
                     LVFEYYLITAKTFTHNFLPRLGLALSFLAIILVFFFLLKKRSFYYPKFIKFFWRTGFL
                     LTLIMYIEMIVELFLMK"
     gene            10347..11303
                     /locus_tag="ACL3EZ_000006"
                     /pseudo
     CDS             10347..11303
                     /locus_tag="ACL3EZ_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002881980.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein.; internal stop;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
     gene            11287..11844
                     /locus_tag="ACL3EZ_000007"
     CDS             11287..11844
                     /locus_tag="ACL3EZ_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGR0391664.1"
                     /translation="MKRPLEMAHDFLAEVVTKEDVVVDATMGNGHDTLFLAKLAKQVY
                     AFDIQKQALEKTQERLHQAGLTNAQLILQGHETLDQFVTKAKAGIFNLGYLPSADKSV
                     ITRPQTTIEALEKLCGLLVKGGRIAIMIYYGHEGGDLERDAVLDFVIQLNQQEYTAAI
                     YRTLNQVNNPPFLVMIEKLERYRHG"
     gene            11837..12091
                     /locus_tag="ACL3EZ_000008"
     CDS             11837..12091
                     /locus_tag="ACL3EZ_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0391665.1"
                     /translation="MDKQYLHEKLDAMRQNFVESTYHERAVGVLDQAHMSKKMLKIKK
                     KLVALEMERCQRKIEHKDCSKIDQKIKEQKEIFESCCKKD"
     gene            12103..14157
                     /locus_tag="ACL3EZ_000009"
     CDS             12103..14157
                     /locus_tag="ACL3EZ_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HGR0391666.1"
                     /translation="MELLIYLILFLLVLIVSSTTNKLLPFLPLPLVQILLGIVIGLFL
                     PNTDFHLNTELFLALVIGPLLFREAEEADVTAILKHWRIIVYLIFPVIFISTLSLGGL
                     AHLLWFSLPLAACLAVGAALGPTDLVAFASLSERFSFPKRVSNILKGEGLLNDASGLV
                     AFQVALTAWTTGAFSLGQASSSLIFSILGGFLIGFLTAMTNRFLHTFLLSVRATDIAS
                     ELLLELSLPLVTFFLAEEVHVSGIIAVVVAGILKASRFKKITLLEAQVDTVTETVWHT
                     VTFMLNGSVFVILGMELEMIAEPILTNPIYNPLLLLLSLIALTFVLFVIRFIMIYGYY
                     AYRTRRLKKKLNKYMKDMFLLTFSGVKGTVSIATILLIPSNLEQEYPLLLFLVAGVTL
                     VSFLTGLLVLPHLSDEEEESKDYLMHIAILNEVTLELEKELEDTRNKLPLYAAIDNYH
                     GRIENLILSQENQDDQEDWAALKLLILSIESDGLEQAYEEGNISNRAYRVYQRYLKNI
                     EQGINRKLASRLTYYFLVSLRILRFLLHEVFTLGKTFRSWKDKEQSRLRALDYDQIAE
                     LYLANTEMIIESLENLKGVYRRSLISFMQESRLRETAIISSGAFVERVINRVKPNNID
                     EMLRGYYLERKLIFEYEEKRLITTKYAKKLRQNVNNLENYSLKEAANTLPYDMVELVR
                     RN"
     gene            14336..15196
                     /locus_tag="ACL3EZ_000010"
     CDS             14336..15196
                     /locus_tag="ACL3EZ_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HGR0391667.1"
                     /translation="MKKWWKELIDKPLLKAFLHYYQASDSELTSVAVAYYWLISIFPL
                     LLVVVNILPYFQIPVGEFLGFMKDVLPPSLYEGVEKIAREVLTQPSTGLLSFSVLSAL
                     WSFSKSMNFLQKAFNKAYGVEKSRGLISHQMLSLLVSFGLQLLFAFALFLILFGQMIL
                     ALLAHYWTKDGIIYQALQGLAGPLIYALLFAILVMLYYFLPNLSNRKISYTLPGSAFV
                     LLVILGLLTLFSSYLNYYVHHLVDVRILGSVLLVVMMFWFILIAKIVILGAVINASMQ
                     SLKDPVFKKD"
     gene            15407..16117
                     /gene="ccdA2"
                     /locus_tag="ACL3EZ_000011"
     CDS             15407..16117
                     /gene="ccdA2"
                     /locus_tag="ACL3EZ_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000509848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HGR0391668.1"
                     /translation="MGHIFFFLSVFLAGILSFFSPCILPLLPVYTGVLLDDKDGAQAS
                     SGKFSISVTSLLRTLAFIAGISFIFILLGYGAGFLGDLLYASWFQYLTGAIIILLGLH
                     QMEILHFKGLYKEKRLQLQGQGQNGKGYSQAFLLGLTFSFAWTPCVGPVLGSVLALAA
                     SGGSGAWQGAGLMLVYTLGLALPFLLLALTSSYVLKHFRKLHPYLGILKKVGGFLIIV
                     MGLLVLFGNASILSQLFE"
     gene            16137..16703
                     /locus_tag="ACL3EZ_000012"
     CDS             16137..16703
                     /locus_tag="ACL3EZ_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin family protein"
                     /protein_id="HGR0391669.1"
                     /translation="MKKWQTCVLGAGSLLCLTACSGKSVTSEHQTKDEMKTEQTASKT
                     SAAKGKEVADFELMGVDGKTYRLSDYKGKKVYLKFWASWCSICLASLPDTDEIAKEAG
                     DDYVVLTVVSPGHKGEQSEADFKNWYKGLDYKNLPVLVDPSGKLLETYGVRSYPTQAF
                     IDKEGKLVKTHPGFMEKDAILQTLKELA"
     gene            16714..17826
                     /gene="msrB"
                     /locus_tag="ACL3EZ_000013"
     CDS             16714..17826
                     /gene="msrB"
                     /locus_tag="ACL3EZ_000013"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033743 - peptide-methionine (R)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HGR0391670.1"
                     /translation="MNDKLKIFLLLGVFFLAITGFYVLLIRNAGQTDASQIEKAAVSQ
                     GGKAVKKTEISKDADLHEIYLAGGCFWGVEEYFSRVPGVTDAVSGYANGRGETTKYEL
                     INQTGHAETVHVTYDAKQISLKEIMLHYFRIINPTSKNKQGNDVGTQYRTGVYYTDDK
                     DLEVINQVFDEVAKKYDQPLAVEKENLKNFVVAEDYHQDYLKKNPNGYCHINVNQAAY
                     PVIDASKYPKPSDEELKKTLSPEEYAVTQENQTERAFSNRYWDKFESGIYVDIATGEP
                     LFSSKDKFESGCGWPSFTQPISPDVVTYKEDKSYNMTRMEVRSRVGDSHLGHVFTDGP
                     QDKGGLRYCINSLSIRFIPKDQMEEKGYAYLLDYVD"
     gene            18094..18831
                     /locus_tag="ACL3EZ_000014"
     CDS             18094..18831
                     /locus_tag="ACL3EZ_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HGR0391671.1"
                     /translation="MTYTILIVEDEYLVRQGLTKLVNVAAYDMEIIGQAENGRQAWEL
                     IQKQVPDIILTDINMPHLNGIQLASLVRETYPQVHLVFLTGYDDFDYALSAVKLGVDD
                     YLLKPFSRQDIEEMLGKIKQKLDKEEKEEQLQDLLTNRFEGNMAQKIQSHLADSQFSL
                     KSLASDLGFSPTYLSSLIKKELGLPFQDYLVRERVKQAKLLLLTTDLKIYEIAEKVGF
                     EDMNYFTQRFKQIAGVTPRQFKKGEDR"
     gene            18828..20519
                     /locus_tag="ACL3EZ_000015"
     CDS             18828..20519
                     /locus_tag="ACL3EZ_000015"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HGR0391672.1"
                     /translation="MKRSSLLVRMVISIFLVFLILLALVGTFYYQSSSSAIEATIEGN
                     SQTTISQTSHFIQSYIKKLETTSTGLTQQTDVLAYAENPSQDKVEGIRDLFLTILKSD
                     KDLKTVVLVTKSGQVISTDDSVQMKTSSDMMAEDWYQKAIHQGAMPVLTPARKSDSQW
                     VISVTQELVDAKGANLGVLRLDISYETLEAYLNQLQLGQQGFAFIINENHEFVYHPQH
                     TVYSSSSKMEAMKPYIETGQGYTPGHKSYVSQEKIAGTDWTVLGVSSLEKLDQVRSQL
                     LWTLLGASVTSLLVCLCLVWFSLKRWIAPLKDLRETMLEIASGAQNLRAKEVGAYELR
                     EVTRQFNAMLDQIDQLMVAIRSQEETTRQYQLQALSSQINPHFLYNTLDTIIWMAEFH
                     DSQRVVQVTKSLATYFRLALNQGKDLICLSDEINHVRQYLFIQKQRYGDKLEYEINEN
                     VAFDNLVLPKLVLQPLVENALYHGIKEKEGQGHIKLSVQKQDSGLVIRIEDDGVGFQD
                     AGDSSQSQLKRGGVGLQNVDQRLKLHFGANYQMKINSRPQKGTKVEIYINRIETS"
     gene            20635..21198
                     /locus_tag="ACL3EZ_000016"
     CDS             20635..21198
                     /locus_tag="ACL3EZ_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HGR0391673.1"
                     /translation="MNETQIQRETRQVVEDVLEKTNLKQGALFVLGLSSSEVLGGQIG
                     KESSQEIGELIVETILGILGSRGIHLAVQGCEHVNRALVVERQVAEQFGLEIVSVHPT
                     LHAGGSGQLAAFKFMQDPVEVEFIKAHAGLDIGDTAIGMHVKHVQVPIRPILREIGHA
                     HVTALASRPKLIGGARAHYPQDAIRKT"
     gene            21220..26889
                     /locus_tag="ACL3EZ_000017"
     CDS             21220..26889
                     /locus_tag="ACL3EZ_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005576 - extracellular region [Evidence
                     IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ZmpA/ZmpB/ZmpC family metallo-endopeptidase"
                     /protein_id="HGR0391674.1"
                     /translation="MFKKDRFSIRKIKGVVGSVFLGSLLMAPSVVDAATYHYVNKEII
                     SQEAKDLIQTGKPDRNEVVYGLVYQKDQLPQTGTEASVLTAFGYLSGDILKTLGLDTV
                     LEETSAKPGEVTVVEVETPQSTTNQEQARTENQVVETEEAPKEEAPKTEESPKEEPKS
                     EIKPTDDTLPKVEEGKEDSAEPAPVEEVGGEVESKPEEKVAVKPESQPSDKPTEEPKV
                     EQVGEPVEPSEDEQAPTAPVEPEKQPEAPEEEKAVEETPKPEDKIKGIGTKEPVDKSE
                     LNNQIDKASSVSPTDYSTASYNDLGPVLETAKGVYASEPVKQPEVNSETNKLKTAIDA
                     LNVDKTELNNTIADAKTKVKEHYSDRSWQNLQTGVTKAEKVAANTDAKQSEVNSETAS
                     LKTAISGLNTDKVELENQLKIAQGKTETDFSMESWTVLSTAKNKAQEVKDNGTATQEQ
                     INEAEKSLKTALADLSVDKTALGSAIDTATKKNKENYTNQTWAELETVLTAAKSVNTN
                     ESKQSEVNEAVEKLTATIEKLVELSEKPRLTLSIEKRDIDRKVTVTYTLENPANTQIK
                     SITATLKKGEEVVKDFVLTEENLKTNHLTALFEKLDYYKEYTLSTDMVYNRGNDDETE
                     SISEELIQLNLKKLELKDIQTVSLMKFENGQESQVTHLSDKPTDLSKLYLKVTSSTSK
                     DAVLAVSSIEEEIVENKKIFKIHADTPELVVRKKDGSLSKGFDYYMERVIPHDGDIYY
                     DFKDLISAMTSNPTGTFILGRDISSRNVKPDGNGKSYIKGEFKGKLLGTNDNVRHSIF
                     DLEYPLFDTIKSGVVKDIDFKHVNMVFPDSNQGDNVATIARVIKDKTKIENVNVEGYL
                     EGRDHVAGLVNNLEGNSEIENISFTGKIKSKGGNSITAGIAGRNILSRVKRAYVNANI
                     EVLGSTNSSMLVAVNGTTLNASGGWGAWGRLTESVAKGTLEIKRSGQAGGVTATVWPY
                     GAIDKVVSYAKVTKGKELFGSDGDLNNNWFMQKINNIFGVQGISSGDSGNDSKFKRIS
                     EEEAKQKVASYNITAPNLMSDSSLLVDRLNESWKNTDQFESIQDYQSQNQLIYQNLTK
                     FTPYYNKEFIVHEGNALTPEQEILKTKKIKSIVGLKGTEFVVDGSDIDTIMLHFEDGS
                     QKRYKVTSTGKFSITNLPEYQVEDLNVVYTSEHIVHPLDSSLINNLVEELKKVELYTE
                     STYQVLGIDKDNANKLNRTKRLFLDESLDAVKTQLPTFVKTMFENEWLHINGESSGAV
                     AALRQKIMDNKTAILLALTYINRYYDVKFSDYNIKKLMLFKPTFHGEKIDLLDRLIRL
                     GSSGENRLKGSENAETFKQLFASETKQKDLVTYLDYNRSLLTNYQTTGEWFKETTKDY
                     IQFEERPSLVEEIKDAKYRVYDNLTAPYYQGYILPLLTLKNTHLAILSNYSTMTFVSR
                     EKRPNWKNEDFDKWVKYVATAHRNHVDTWYKILPDNIKGKMVKENVTAVWEGLSIPGS
                     EWVDQNAVDRKGRDYAPAREFFNLVGGPMGGWYAYHGYGAHAGGRNRVNYEVFDVLSE
                     YGISVFTHELTHVNDTWIYLGGYGRRENMGPEAYAQGLFQSPVPGQPGWGALGLNMAF
                     ERKNDGDLIYNASPTQFENRKELDSYMKNYNDTLMMVDYLEGDAVISKGKEAITKWFK
                     KVEPKVVSQTAQYDTVRQLTAEEKEKLSVSSVDDLVDQGLMSDRAVGNNTYNPADFET
                     SYIAIDYMTGIYGGGKNSVGSPGALMFKHNTFRMWGYYGFEEGVLGYASNKFKQASRD
                     EGHAGLSDNFIISKISKGEFLTMEAFKKGYFKKVVEELKTKGIRPVTINQKTYSTFEE
                     LQEGFKQAVERDLKKNQLDERETRNFKFQVFRQLLQQTDSFKTSIFR"
     gene            26950..28671
                     /gene="pabB"
                     /locus_tag="ACL3EZ_000018"
     CDS             26950..28671
                     /gene="pabB"
                     /locus_tag="ACL3EZ_000018"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000554849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046820 - 4-amino-4-deoxychorismate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0008153 - para-aminobenzoic acid
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009396 - folic acid-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HGR0391675.1"
                     /translation="MHRKTVIDFRTLGERYTFTQPIKELKTRNVEEVADLLAQVESYQ
                     EQGYYVVGYVSYEAAPAFEEKLAVHKDPLLGEYLLYFTVHDSVETSPIPLTYEDIDLP
                     SNWQEVTSAADYEKAIAQIHHHLRQGDTYQVNYTVQLKQKLNANPFAIYNRMVVEQEA
                     GYNAYVEHDEMAVISMSPELFFEQNDRELTTRPMKGTTQRGVTDQEDLEQASWLEQDP
                     KNRSENMMIVDLLRNDMNRISEVGSEHVERLCQVEQYSTVWQMTSTIKSQLREDVDLV
                     EIFHSLFPCGSITGAPKIATMEIIKDLEPQPRGVYCGTIGLLLPNGRRIFNVAIRTIQ
                     LHKGQAIYGVGGGITWDSTWESEYREVHQKAAVLYRKQARFQLITTGKISQKQLMFEE
                     QHLERLRKASRYFAYPFDPEILRQKIEAECQTCDANQDYRLRISLSKSGEIEFSRQIL
                     TPLSPSFCQAKLCLQEANLNQSFTYFKTTYRPHLSIEEQEKIYHNGKGELLETSIGNL
                     VLKIDGKLYTPPIRLGILPGIYHQYLLETGQVEEKVLTLADFAQAEAIYGCNAVRGLY
                     ELQVIGL"
     gene            29202..30317
                     /locus_tag="ACL3EZ_000019"
     CDS             29202..30317
                     /locus_tag="ACL3EZ_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HGR0391676.1"
                     /translation="MSKGDFIDPKTQFKHQYRGESPVFRIRNRKYVELGTTDKKLDER
                     RDNSVYKDGVVEHKVNLSLTSYQGGNGVTAIFSTDSVNSNLLNSFGEKAKKVLIRSKL
                     INVKTGEVIDETFSPKVSLTSKILKSGSTAVFYFIDLTDGEYKYVAYESQQYTDPQTT
                     LTHQYRGESPIFSIKDGKFSGLVSASKPDENPKPTPKPDEKPKPSAPQQEKTKPTVQS
                     GWVGSSYYQNGKKVTSKWIFDKKYNSYFYLDASGNYVQNAWVGNYYLKSGGYMAKSEW
                     IYDKNYGSYYYLTSEGSYARNTWSGNYYLKSNGKMAKSEWVYDSNYKSYYYLTSEGSY
                     ARNTWVGNYYLKSNGKMAVNERTPDGYRVDGSGKWVK"
     gene            30404..31323
                     /locus_tag="ACL3EZ_000020"
                     /pseudo
     CDS             30404..31323
                     /locus_tag="ACL3EZ_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811638.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Ltp family lipoprotein"
     gene            31458..32417
                     /locus_tag="ACL3EZ_000021"
     CDS             31458..32417
                     /locus_tag="ACL3EZ_000021"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002919069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004340 - glucokinase activity [Evidence
                     IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA];
                     GO_process: GO:0051156 - glucose 6-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HGR0391677.1"
                     /translation="MSQKIIGIDLGGTSIKFAILTTAGEIQGKWSIKTNILDEGSHIV
                     DDMIESIQHRLDLLGLAAADFQGIGMGSPGVVDREKGTVIGAYNLNWKTLQPIKQKIE
                     KALGIPFFIDNDANVAALGERWMGAGDNQPDVVFMTLGTGVGGGIVAEGKLLHGVAGA
                     AGELGHITVDFDQPIACTCGKKGCLETVASATGIVNLTRRYADEYEGDAALKRLIDNG
                     EEVTAKTVFELAKEEDDLALIVYRNFSRYLGIACANIGSILNPSTIVIGGGVSAAGEF
                     LLQGVQKVYDENSFPQVRTSTKLALATLGNDAGVIGAASLVLQ"
     gene            32514..33353
                     /locus_tag="ACL3EZ_000022"
     CDS             32514..33353
                     /locus_tag="ACL3EZ_000022"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HGR0391678.1"
                     /translation="MTKADTIFKENIERILKEGVFSEQARPKYKDGTVANSKYVTGAF
                     SEYDLSKGEFPITTLRPIAIKSAIKEVLWIYQDQSNSLEVLNDKYNVHYWNDWEVGDT
                     GTIGERYGAVVKKHDIINKLLKQLETNPWNRRNIISLWDYQAFEETDGLLPCAFQTMF
                     DVRRVDGEIYLDATLTQRSNDMLVAHHINAMQYVALQMMIAKHFGWKVGKFFYFINNL
                     HIYDNQFEQAQELLRREPSNCQPRLVLNVPDGTNFFDIKAEDFELVDYDPVKPQLKFD
                     LAI"
     gene            complement(33401..33571)
                     /locus_tag="ACL3EZ_000023"
     CDS             complement(33401..33571)
                     /locus_tag="ACL3EZ_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002263068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HGR0391679.1"
                     /translation="MAKGFAKGLVTGVAGTVAAVAGAVYAFKKKVIEPEEQKAAFIEE
                     NRKKAARRRVSR"
     gene            33692..34576
                     /gene="miaA"
                     /locus_tag="ACL3EZ_000024"
     CDS             33692..34576
                     /gene="miaA"
                     /locus_tag="ACL3EZ_000024"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0052381 - tRNA dimethylallyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HGR0391680.1"
                     /translation="MKTKIIVIVGPTAVGKTALAIEVAKRFNGEVVSGDSQQVYRGLD
                     IGTAKASPEEQAAVPHHLIDVREITESYSAFDFVSEAKMTIEDIQSRGKLAIIAGGTG
                     LYIQSLLEGYHLGGETPHEEILAYRASLEPYSDEELAHLVEQAGLEIPQFNRRRAMRA
                     LEIAHFGQDLENQEILYEPLIICLDDERSQLYERINHRVDLMFEAGLLDEAKWLFDHS
                     PNVQAAKGIGYKELFPYFRGEQTFEEARESLKQATRRFAKRQLTWFRNRMQVTFYQIG
                     ESGVQDRILSQIEEFLDD"
     gene            34569..35807
                     /gene="hflX"
                     /locus_tag="ACL3EZ_000025"
     CDS             34569..35807
                     /gene="hflX"
                     /locus_tag="ACL3EZ_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HGR0391681.1"
                     /translation="MIETEKKEERVLLIGVELQGMDSFDLSMEELASLAKTAGAVVVD
                     SYRQKREKYDSKTFVGSGKLEEIALMVDAEEITTVIVNNRLTPRQNVNLEEVLGVKVI
                     DRMQLILDIFAMRARSHEGKLQVHLAQLKYLLPRLVGQGIMLSRQAGGIGSRGPGESQ
                     LELNRRSVRNQITDIERQLKVVEKNRATVREKRLESSTFKIGLIGYTNAGKSTIMNIL
                     TSKTQYEADELFATLDATTKSIHLGGNLQVTLTDTVGFIQDLPTELVSSFKSTLEESK
                     HVDLLVHVIDASNPYHEEHEKTVLSIMKDLDMEDIPHLTLYNKADLVEDFTPTQTPYT
                     LISAKSEDSRENLQALLLDKIKEIFEAFTLRVPFSKSYKIHDLESVAILEERDYQEDG
                     EVITGYISEKNKWRLEEFYD"
     gene            35800..36423
                     /locus_tag="ACL3EZ_000026"
     CDS             35800..36423
                     /locus_tag="ACL3EZ_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HGR0391682.1"
                     /translation="MTDIKTLALKYGGYTSLDKVYLDQLLAGKTDQEQLTLITPPPSV
                     VNAYFAELYQKKSPQAATDYFAELSQELNLYNTEPSFTLENKPFIRLNLSGKSFGFCY
                     ESDGLGRIFFENEEKISDDLLFEIAQIFPHQLVFEESGKIYMKPVEDEEVISLESLTA
                     LTDLERLTDGRKRLKGYSQEDLLQEAAAFSGKRYFRSENRTAMLYID"
     gene            36438..37367
                     /gene="rnz"
                     /locus_tag="ACL3EZ_000027"
     CDS             36438..37367
                     /gene="rnz"
                     /locus_tag="ACL3EZ_000027"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016891 - RNA endonuclease activity,
                     producing 5'-phosphomonoesters [Evidence IEA];
                     GO_process: GO:0042780 - tRNA 3'-end processing [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HGR0391683.1"
                     /translation="MDIQFLGTGAGQPSKARNVSSLALKLLDEINEVWLFDCGEGTQN
                     RILETTIRPRKVSKIFITHLHGDHIFGLPGFLSSRAFQANEEQTDLEIYGPQGIKSFV
                     LTSLRVSGSRLPYRIHFHEFDQDSLGKILETDKFTVYAEELDHTIFCVGYRVMQKDLE
                     GTLDAEKLKAAGVPFGPLFGKIKNGQDLVLEDGTEIKAADYISAPRPGKIITILGDTR
                     KTGASVRLAVNADVLVHESTYGKGDEKIARNHGHSTNMQAAQVAVEAGAKRLLLNHIS
                     ARFLSKDISKLKKDAATIFENVHVVKDLEEVEI"
     gene            37388..38143
                     /locus_tag="ACL3EZ_000028"
     CDS             37388..38143
                     /locus_tag="ACL3EZ_000028"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HGR0391684.1"
                     /translation="MPTILITGASGGLAQEMVKLLPNDQLILLGRNKEKLAQLYGNYS
                     HAELIEIDITDDSALEALVTDLYLRYGKIDVLINNAGYGIFEGFDQIADKDIHQMFEV
                     NTFALMNLSRHLAARMKESSKGHIINIVSMAGLIATGKSSLYSATKFAAIGFSNALRL
                     ELMPYGVYVTTVNPGPIRTGFFDQADPDGTYLKSVDRFLLEPDAVAKKIVKIIGKNKR
                     ELNLPILLNLAHKFYTLFPKLADKLAGETFNYK"
     gene            complement(38197..39105)
                     /locus_tag="ACL3EZ_000029"
     CDS             complement(38197..39105)
                     /locus_tag="ACL3EZ_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HGR0391685.1"
                     /translation="MRIQQLHYIIKIVETGSMNEAAKQLFITQPSLSNAVRDLENEMG
                     IEIFIRNPKGITLTRDGMEFLSYARQVVEQTQLLEERYKNPVAHRELFSVSSQHYAFV
                     VNAFVSLLKKSDMEKYELFLRETRTWEIIDDVKNFRSEVGVLFLNSYNRDVLTKMLDD
                     NHLLAHHLFTAQPHIFVSKTNPLAKKDKVKLSDLENFPYLSYDQGTHNSFYFSEEILS
                     QEHHKKSIVVSDRATLFNLLIGLDGYTIATGILNSNLNGDNIVSIPLDIDDPIELVYI
                     QHEKTSLSKMGERFIDYLLEEVQFDS"
     gene            39169..39438
                     /locus_tag="ACL3EZ_000030"
     CDS             39169..39438
                     /locus_tag="ACL3EZ_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HGR0391686.1"
                     /translation="MSLFLKKTQNFARMSLMKTFYDVQQFLKRFGIIVYMGKRLYDIE
                     LMKLELSRIYDAGLMDKLDYLEAEAVLRREHKVELDYIEKNGEKN"
     gene            39438..39818
                     /locus_tag="ACL3EZ_000031"
     CDS             39438..39818
                     /locus_tag="ACL3EZ_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HGR0391687.1"
                     /translation="MVTWILWALILAMLAWMGFNYLRIRRAAKIVDNEEFEALIRTGQ
                     LIDLRDPAEFHRKHILRARNIPSSQLKTSLAALRKDKPVLLYENQRAQRVTNAALYLK
                     KQGFSEIYILSYGLDSWKGKVKTS"
     gene            39907..40134
                     /locus_tag="ACL3EZ_000032"
     CDS             39907..40134
                     /locus_tag="ACL3EZ_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0391688.1"
                     /translation="MKEKKKNPLFVGILSIILGLLFPIVGLILGIIGLVLAISYQKES
                     QLDYKIEKILNILGIVISVVNWIVAIALIFR"
     gene            complement(40174..40899)
                     /locus_tag="ACL3EZ_000033"
     CDS             complement(40174..40899)
                     /locus_tag="ACL3EZ_000033"
                     /EC_number="5.4.99.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_function: GO:0140098 - catalytic activity, acting on
                     RNA [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA pseudouridine(516) synthase"
                     /protein_id="HGR0391689.1"
                     /translation="MRLDNLLAQEKISRKAMKQALLRGEILVDSCPARSLAQNIDTGL
                     QELLFQDRIIQGYEHTYLMLHKPAGVVTANKDKELPTVMDLLPSDIQSDKLYAVGRLD
                     RDTTGLLLLTDNGPLGFQLLHPQYHVDKTYQVEVNGLLTPDHIQAFQKGIVFLDGTVC
                     KPAKLEILSASPSISQASITISEGKFHQIKKMFLSVGVKVTSLKRIQFGDFTLNPDLA
                     EGNYRPLNQKELQIIKNYLEMSR"
     gene            41061..42902
                     /gene="typA"
                     /locus_tag="ACL3EZ_000034"
     CDS             41061..42902
                     /gene="typA"
                     /locus_tag="ACL3EZ_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003078415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0006950 - response to stress [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HGR0391690.1"
                     /translation="MTKLREDIRNIAIIAHVDHGKTTLVDELLKQSETLDARTELAER
                     AMDSNDIEKERGITILAKNTAVAYNGTRINIMDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQDLVPIVVVNKIDKPSARPAEVVDEVLELFIELGADDDQ
                     LDFPVVYASAINGTSSLSDDPADQEATMAPIFDTIIDHIPAPVDNSDEPLQFQVSLLD
                     YNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERREIQEAKAG
                     DLIAVSGMEDIFVGETITPTDAVEALPILHIDEPTLQMTFLVNNSPFAGKEGKWVTSR
                     KVEERLQAELQTDVSLRVDPTDSPDKWTVSGRGELHLSILIETMRREGYELQVSRPEV
                     IVKEIDGVKCEPFERVQIDTPEEYQGSVIQSLSERKGEMLDMISTGNGQTRLVFLVPA
                     RGLIGYSTEFLSMTRGYGIMNHTFDQYLPLIPGEIGGRHRGALVSIDAGKATTYSIMS
                     IEERGTIFVNPGTEVYEGMIIGENSRENDLTVNITKAKQMTNVRSATKDQTAVIKTPR
                     ILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAEREKANKKKKSAE"
     gene            42922..43176
                     /locus_tag="ACL3EZ_000035"
     CDS             42922..43176
                     /locus_tag="ACL3EZ_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3165 family protein"
                     /protein_id="HGR0391691.1"
                     /translation="MVYLVLGILLLLLYVFATPESIKGTVNIVAMVCILVALLILLVL
                     SFLKIFQLPTEIFLAIAMLILAYFSVRDITLMPVKKSKRR"
     gene            43541..43840
                     /locus_tag="ACL3EZ_000036"
                     /pseudo
     CDS             43541..43840
                     /locus_tag="ACL3EZ_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397967.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
     gene            43911..45932
                     /locus_tag="ACL3EZ_000037"
     CDS             43911..45932
                     /locus_tag="ACL3EZ_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000732428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HGR0391692.1"
                     /translation="MKKLFILLSTFFLSFFLAWIIVLRAPQYLYASYDSVSLLRVKKD
                     TQEPTREVFEQELENFANSEQSLIARRIVEPSKDGTTHFTYATYGQGTLPKEFQEASQ
                     ESRERSDPLNSYLLLSGSLTKEKLADKLGDLGYKASADRKIPPYFLAFRILLNPLILI
                     SLAIFGLSFFALVIITRIKEMRAAGIKLFSGQTLLSIMGHSLSTDIKWLLLSALLSFL
                     GGGVVLFSQGLFYPILLATYGFGISFYLLFLLAISILLMLLYLMSLNYKALVPVIKGR
                     LPLKRLMILTLLCQLVAVFTVGYAVKTGLTSYQRLKELEISKQAWQDRADYYQISFGL
                     GDRGKDTENQSKWYAFAKEAIEEEQALYVKDNLLHFANPQGKNEQGETLDTYSPDANT
                     LYVSPSYLDKEKVVVDAETKQKLAHLQKGEFILLLPEHLRSREAELKKVFEERLSYYG
                     KSGEEASAPLDYEMKAHVSYLSMGEKRFVYNNGENPVSTQYLTDPILVVFTPTSTGDS
                     FISLSSWSINAGKQLFIKGYESGLELLKKAGIYEQVSYLKEGRSVYLTRYNEVQTETA
                     TLILGAIVGIASSLLLFYSVNLLYFEQFRRDILIKRISGLRFFETHAQYMVSQFASFV
                     FGASFFILRSRDWVIGLLTLLVFLASAVLTLYRQAQKESRVSMTIMKGK"
     gene            45934..46575
                     /locus_tag="ACL3EZ_000038"
     CDS             45934..46575
                     /locus_tag="ACL3EZ_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0391693.1"
                     /translation="MIELKNISKKFGSRQLFSDTNLHFEGGKIYALIGTSGCGKTTLL
                     NMIGRLEPYDKGQIIYDGTSLKDIKPSVFFRDYLGYLFQDFGLIESQTVKENLDLGLV
                     GKKLKEKEKISLMKQALNRVNLSYLDLKQPIFELSGGEAQRVALAKIILKDPPLILAD
                     EPTASLDPKNSEELLSILESLKNPNRTIIIATHNPLIWGQVDQVIRVTDLSHR"
     gene            46679..48031
                     /gene="murD"
                     /locus_tag="ACL3EZ_000039"
     CDS             46679..48031
                     /gene="murD"
                     /locus_tag="ACL3EZ_000039"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008764 -
                     UDP-N-acetylmuramoylalanine-D-glutamate ligase activity
                     [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HGR0391694.1"
                     /translation="MKVIDQFKNKKVLVLGLAKSGESAARLLDKLGAIVTVNDGKPFE
                     DNPAAQCLLEEGIKVITGGHPLELLDEEFALMVKNPGIPYSNPMIEKALAKGIPVLTE
                     VELAYLISEAPIIGITGSNGKTTTTTMIGEVLTAAGQHGLLSGNIGYPASQVAQIASD
                     KDTLVMELSSFQLMGVQEFHPEIAVITNLMPTHIDYHGSFSEYVAAKWNIQNKMTAAD
                     FLVLNFNQDLAKDLTSKTEATVVPFSTLEKVDGAYLEDGQLYFRGEVVMAANEIGVPG
                     SHNVENALATIAVAKLRGVDNQTIKETLSAFGGVKHRLQFVDDIKGVKFYNDSKSTNI
                     LATQKALSGFDNSKVVLIAGGLDRGNEFDELVPDITGLKKMVILGQSAERVKRAADKA
                     GVAYVEATDIADATRKAYELATQGDVVLLSPANASWDMYANFEVRGDLFIDTVAELKE
                     "
     gene            48033..49091
                     /locus_tag="ACL3EZ_000040"
     CDS             48033..49091
                     /locus_tag="ACL3EZ_000040"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0050511 -
                     undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase activity [Evidence
                     IEA];
                     GO_function: GO:0051991 -
                     UDP-N-acetyl-D-glucosamine:N-acetylmuramoyl-L-alanyl-D-
                     glutamyl-meso-2,
                     6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol
                     4-beta-N-acetylglucosaminlytransferase activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0007049 - cell cycle [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0030259 - lipid glycosylation [Evidence
                     IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HGR0391695.1"
                     /translation="MKKIVFTGGGTVGHVTLNLLLMPKFIEDGWEVHYIGDKRGIEHQ
                     EILKSGLDVTFHSIATGKLRRYFSWQNMLDVFKVGWGIVQSLFIMLRLRPQALFSKGG
                     FVSVPPVIAACVSGVPVFIHESDLSMGLANKIAYKFATKMYSTFEQASSLSKVEHVGA
                     VTKVSDQKNPEPDELVDIQSHFNHKLPTVLFVGGSAGARVFNQLVTDHKKELTERYNI
                     INLTGDSSLNELSQNLFRVDYVTDLYQPLMELADIVVTRGGANTIFELLAIAKLHVIV
                     PLGREASRGDQIENAAYFVKKGYAEDLQESDLTLDSLEEKLSHLLSHKEDYQAKMKAS
                     KELKSLADFYQLLKKDLS"
     gene            49101..50321
                     /gene="divIB"
                     /locus_tag="ACL3EZ_000041"
     CDS             49101..50321
                     /gene="divIB"
                     /locus_tag="ACL3EZ_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIB"
                     /protein_id="HGR0391696.1"
                     /translation="MSKDKKNEDKEILEELKELSEWQKRNQEYLKKKAEEEAALAEEK
                     EKERQARMGEESEKSEDKQDQESETDQEDSESAKEESEEKVASSEADKEKEEKEEPES
                     KEKEEQDKKLAKKATKEKPAKAKIPGIHILRAFTILFPSLLLLIVSAYLLSPYATMKD
                     IRVEGTVQTTADDIRQASGIQDSDYTINLLLDKAKYEKQIKSNYWVESAQLVYQFPTK
                     FTIKVKEYDIVAYYISGENHYPILSSGQLETSSVSLNSLPETYISVLFNDSEQIKAFT
                     SELAQINPELKVAIQKVELAPSKVTSDLIRLTMNDSDEVLVPLSEMSKKLPYYSKIKP
                     QLSEPSVVDMEAGVYSYTVADKLIMEAEEKAKKEAEEAEKRQEEERKRLEEEQKKQEE
                     ESNRNQTTQRSSRR"
     gene            50453..50578
                     /locus_tag="ACL3EZ_000042"
     CDS             50453..50578
                     /locus_tag="ACL3EZ_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0391697.1"
                     /translation="MSDEVFLFEEIEEIVAPTDGEFWGGVLLGTGVVLLIGVACC"
     gene            50599..50721
                     /locus_tag="ACL3EZ_000043"
     CDS             50599..50721
                     /locus_tag="ACL3EZ_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0391698.1"
                     /translation="MQDNFLFEEIEEISVPVSDFSAGLATGIGLGLAILALAGC"
     gene            50904..51911
                     /locus_tag="ACL3EZ_000044"
     CDS             50904..51911
                     /locus_tag="ACL3EZ_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001223420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M50 family protein"
                     /protein_id="HGR0391699.1"
                     /translation="MRIVDKIKILPTPYEGQYHLYIPSSKKHVLVGKQEKKWLEQLIG
                     QEFTISDLLVLVGKKYYLRFYIVLSKMGLIDSMKSRKKINIFKISWDFNITLSEKLNY
                     KRFNKNFEKILFGIFPLALILQCFIMYIYRADILTNFQNFPITLNILLFWLLVVIISA
                     TIHEFSHAIIANNYQIEIPNCGIMLLLFNLAFFVDLSGVQFLKNKKQFLKIMLAGIAS
                     NSILSLTGLLVLLFTSYKLLGLLFFIINLGMIFINSIPFFQYDSGIILRYLNSNNNNL
                     NFQYIVQLLIAFVIIYFPLSQLLQFLTPNIIVRSIGGVVVSILLSILYMRGRTKYVLR
                     K"
     gene            51895..53268
                     /locus_tag="ACL3EZ_000045"
     CDS             51895..53268
                     /locus_tag="ACL3EZ_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ThiF family adenylyltransferase"
                     /protein_id="HGR0391700.1"
                     /translation="MFYVNSYVFAYKKEGIMYLRGRSMREIAIEPQISQEFINDLFNS
                     CKELLEIEEVLGSKLTFELLNEQILISDEIDIDSRYSRTKGYYSLFYNEEYNKIQNKT
                     VLVLGAGALGCYISLSLSMYGVRKLIVADYDIIEPSNLNRQILYTESDVGKEKINVLS
                     QKIHKYNSDVQVVPISIKVSSVEELENIVAEYGSIDFIVKAIDTPIDIIKIVNQFAVS
                     HKISYISGGFNGCYLIIDNIYIPTIGSCFACRNINKDINKYTLSDKTKWPTTPEMPAI
                     LGGIMTNLIIKIFLGCYNEILIDNAYVYNMRNHALSQEKYVLENGECPICKKNNKVKD
                     NNIRAKTFIRSVCFCLLSGGVAFLSAIGQFTVIETQLIVLFLGIIFAIYYAYYNKNIQ
                     TSLENIVWLFSSFEILFLLVNFRTFIQLPVDIFISMIIFLMLWIFIMLGIVCLSYYIT
                     LLFSKEA"
     gene            53478..54311
                     /locus_tag="ACL3EZ_000046"
     CDS             53478..54311
                     /locus_tag="ACL3EZ_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0391701.1"
                     /translation="MIEVSHLSKSFGDKIALNDISFTVKEGQIFGFLGPSGSGKTTTI
                     NILTGQLLADKGQSIILGQKSQNLTSGELKRIGLVSDTSGFYEKMSLYNNLLFYSKFY
                     NISKLRVDNLLKRVGLYDSCKMVAGKLSTGMRQRMLLARALINKPAVLFLDEPTSGLD
                     PTTSRTIHELILELKTAGTTIFLTTHDMNEATLLCDYVALLNKGKLVEQGAPSELIQR
                     YNKDKKIKVTDYNGNQITFDFTSLEQVSQADLENIFSIHSCEPTLEDIFITLTGGKLN
                     A"
     gene            54304..55017
                     /locus_tag="ACL3EZ_000047"
     CDS             54304..55017
                     /locus_tag="ACL3EZ_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0391702.1"
                     /translation="MLKRFLALVWLRCQIILSNKSILLQVLVPFAFTYFYKYLMETQG
                     KVNDQQALVLLMMCLPFSLALAVGSPITIILSEEKEKYNLQTLLLSGVKGSEYILSTM
                     FLPFLLTFVIMGTTPLILGVTIVHTFNYITIVLLTSLSIILFYLLIGLTAKSQVVAQV
                     ISLPAMILVAFLPMLSGLDKTVAKITDYSFMGLFTKFFTKWEGFSWNETLIPNLTLLI
                     WIVLLLTLITITIRKKKIS"
     gene            complement(55339..55437)
                     /locus_tag="ACL3EZ_000048"
                     /pseudo
     CDS             complement(55339..55437)
                     /locus_tag="ACL3EZ_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612010.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            55752..56453
                     /gene="pyrF"
                     /locus_tag="ACL3EZ_000049"
     CDS             55752..56453
                     /gene="pyrF"
                     /locus_tag="ACL3EZ_000049"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004590 - orotidine-5'-phosphate
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0044205 - 'de novo' UMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HGR0391703.1"
                     /translation="MREHRPIIALDFPSFEAVKEFLALFPAEESLYLKVGMELYYAAG
                     PEIVSYLKGLGHSVFLDLKLHDIPNTVKSAMKILSQLGVDMTNVHAAGGVEMMKAARE
                     GLGSQAKLIAVTQLTSTSEAQMQEFQNIQTSLQESVIHYAKKTAEAGLDGVVCSAQEV
                     QVIKQATNPDFICLTPGIRPAGVAVGDQKRVMTPADAYQIGSDYIVVGRPITQAEDPV
                     AAYHAIKDEWTQDWN"
     gene            56487..57119
                     /gene="pyrE"
                     /locus_tag="ACL3EZ_000050"
     CDS             56487..57119
                     /gene="pyrE"
                     /locus_tag="ACL3EZ_000050"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004588 - orotate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009220 - pyrimidine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HGR0391704.1"
                     /translation="MTLAKDIASHLLKIQAVYLKPEEPFTWASGIKSPIYTDNRVTLA
                     YPETRTLIENGFVEAIKEAFPEVEVIAGTATAGIPHGAIIADKMDLPFAYIRSKPKDH
                     GAGNQIEGRVAQGQKMVVVEDLISTGGSVLEAVAAAKREGADVLGVVAIFSYQLPKAD
                     KNFADAGVKLVTLSNYSELIHLAQEEGYITPEGLDLLKRFKDDQENWQEG"
     gene            57582..57704
                     /locus_tag="ACL3EZ_000051"
     CDS             57582..57704
                     /locus_tag="ACL3EZ_000051"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0391705.1"
                     /translation="MYYNGGGDNYIGSGTRLAMAPQFGNHVRIHTSGSWSPDSY"
     gene            57800..58564
                     /locus_tag="ACL3EZ_000052"
     CDS             57800..58564
                     /locus_tag="ACL3EZ_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0391706.1"
                     /translation="MEFFICNLVRVVQSPRFYMSLFLTLLCMSLGNFLAFNGIYKIEG
                     LSIFFAASSIRGFSPISLVAALICTLPYSSQIIEDAESHFLTAQLCRISKKRYLAIVG
                     STAIISSFLVFFLPYLLLLGINLLVTPYQEIYIGDYSGALKELFDSNQLLYSLVTTLW
                     YGVWGAVFSIFGLASALLVKKKIGAIFIPVAYMMVGGIFWAILGLSYLEPVTTLALGY
                     QKDISLSLVSGHLAFILFVSCLVVYGTFFLHSEDYV"
     gene            58564..59316
                     /locus_tag="ACL3EZ_000053"
     CDS             58564..59316
                     /locus_tag="ACL3EZ_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0391707.1"
                     /translation="MKQFVQFYKKDFLSVLVYFILLLSCVLSSTVYLLRCRQYSIHPN
                     VLEWILVLLQDMTTGVYCFPFTYILFFFYLMNNYFNRLECRIRLKSIKHFTSFSFKLA
                     ALSTGIWTATLFLLIFLIAFSNGFSFSLEIKEVDFLREFYGISIANNASFFIGFFFSY
                     IAYYFFLSLLTISSFSWFKKSNMSLVFLFTFLFVESLFWIYQLDNGIIGLLPIFQYMV
                     NSNPYALIYWLTLLSIIIPLTVFSVHRNWRRV"
     gene            59326..60024
                     /locus_tag="ACL3EZ_000054"
     CDS             59326..60024
                     /locus_tag="ACL3EZ_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0391708.1"
                     /translation="MGKLSSHMWRLNQIIYTKYFWGYVLFWILICLGLWYWLEGNDRL
                     VIEILKGPNLSQNSFLVLSIWLLHWFIIHTFFLAVVYRRRASDFFLEVIRFSSIKLWI
                     RYQIWTCFLYGLILIMVKVLVIQFMLQLPNWDIGVLFIVDSLNACVLVLFCFMLYALG
                     ANVQMNFACVSFFLLMIVFGGLFVGNRTNYLFYILNRGNGDIGRDLFLQLLFLVFLFK
                     SIFYFTRQKRRFIE"
     gene            60021..60668
                     /locus_tag="ACL3EZ_000055"
     CDS             60021..60668
                     /locus_tag="ACL3EZ_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0391709.1"
                     /translation="MNEIIILKNIELKLKKTCVFQNLNFSCKQGEIIGITGANGSGKS
                     VLFKLIAGLYSPSYGEVLINGENIVPERKIPANLGALIEEPGFINYYSGFKNLQYLAS
                     IRGVVGNQEINDTLKIVGLYEQKDQKVKTYSLGMRKKLGIAQAIMENPSILLLDEPMN
                     ALDKSSVENMRTLFRKLSSEKGTTILIASHSEEDIRILCDKVYAIEDKVCTLCSD"
     gene            complement(60748..61609)
                     /locus_tag="ACL3EZ_000056"
                     /pseudo
     CDS             complement(60748..61609)
                     /locus_tag="ACL3EZ_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765255.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine ABC transporter substrate-binding
                     protein"
     gene            complement(61621..62379)
                     /locus_tag="ACL3EZ_000057"
     CDS             complement(61621..62379)
                     /locus_tag="ACL3EZ_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HGR0391710.1"
                     /translation="MSETILEIKELKKSFGDNPILQGLSLEIKKGEVVVILGPSGCGK
                     STLLRCLNGLESIQGGDIFLDGQSIVENKKNFHLVRQKIGMVFQSYELFPHLDVLQNL
                     ILGPIKTQGRDKKEVTEEALQLLDRVGLLDKQHSFARQLSGGQKQRVAIVRALLMHPE
                     IILFDEVTASLDPEMVREVLELINDLAQEGRTMILVTHEMQFAQAIADRIIFLDQGKI
                     AEEGTAQAFFTNPQTKRAQEFLNVFDFSQFGSYL"
     gene            complement(62380..63057)
                     /locus_tag="ACL3EZ_000058"
     CDS             complement(62380..63057)
                     /locus_tag="ACL3EZ_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001154125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HGR0391711.1"
                     /translation="MQDSGIQVLFQGNNLLRILQGLGVTIGISILSVLLSMMFGTVMG
                     IIMTSHSRIIRFLTRLYLEFIRIMPQLVLLFIVYFGLARNFNINISGETSAIIVFTLW
                     GTAEMGDLVRGAITSLPKHQFESGQALGLTNVQLYYHIIIPQVLRRLLPQAINLVTRM
                     IKTTSLVVLIGVVEVTKVGQQIIDSNRLTIPTASFWIYGTILVLYFAVCYPISKLSTH
                     LEKHWRN"
     gene            complement(63017..63685)
                     /locus_tag="ACL3EZ_000059"
     CDS             complement(63017..63685)
                     /locus_tag="ACL3EZ_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000384089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HGR0391712.1"
                     /translation="MVEQYLPLYQKAFFLTLHIAVWGILGSFLLGLIVSIIRHYRILV
                     LSQVATAYIELSRNTPLLIQLFFLYFGLPRIGIVLSSEVCATLGLVFLGDSYMAESFR
                     SGLEAISQTQQEIGLAIGLTPLQVFYYVVLPQATAVALPSFSANVIFLIKETSVFSAV
                     ALADLMYVAKDLIGLYYETDIALAMLVVAYLIMLLPISLVFSWIERRLRHAGFGNPST
                     LSRK"
     gene            63911..64045
                     /locus_tag="ACL3EZ_000060"
                     /pseudo
     CDS             63911..64045
                     /locus_tag="ACL3EZ_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120720.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
     gene            64185..65675
                     /gene="lysS"
                     /locus_tag="ACL3EZ_000061"
     CDS             64185..65675
                     /gene="lysS"
                     /locus_tag="ACL3EZ_000061"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004824 - lysine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006430 - lysyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HGR0391713.1"
                     /translation="MSTEHMEELNDQQIVRREKMAALREQGIDPFGKRFERTANSQEL
                     KDKYTNLDKEQLHDKNETATIAGRLVTKRGKGKVGFAHLQDREGQIQIYVRKDAVGEE
                     NYEIFKKADLGDFLGVEGEVMRTDMGELSIKATHITHLSKALRPLPEKFHGLTDVETI
                     YRKRYLDLISNRESFERFVTRSKIISEIRRYLDQKGFLEVETPVLHNEAGGAAARPFI
                     THHNAQNIDMVLRIATELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYQ
                     AYADFQDIMDLTEGIIQHAAKSVKGDGPVNYQGTEIKINEPFKRVHMVDAIREITGVD
                     FWQDMTLEEAKAIAAEKKVPVEKHYTEVGHIINAFFEEFVEETLIQPTFVYGHPVAVS
                     PLAKKNPEDQRFTDRFELFIMTKEYGNAFTELNDPIDQLSRFEAQAKAKELGDDEATG
                     IDYDYIEALEYGMPPTGGLGIGIDRLCMLLTDTTTIRDVLLFPTMK"
     gene            66300..67436
                     /gene="lctO"
                     /locus_tag="ACL3EZ_000062"
     CDS             66300..67436
                     /gene="lctO"
                     /locus_tag="ACL3EZ_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate oxidase"
                     /protein_id="HGR0391714.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAEDTF
                     TLRENIRAFNHKLIVPHTLCDVENPSTEIEFAGEKLSSPIIMAPVAAHKLANEQGEVA
                     TARGVHEFGSLYTTSSYSTVDLPEISEALQGTPHWFQFYFSKDDGINRHIMDRVKAEG
                     YKAIVLTADATVGGNREVDKRNGFVFPVGMPIVEEYLPEGAGKSMDFVYKSAKQRLSP
                     RDVEFIAEYSGLPVYVKGPQCREDVERSLAAGASGIWVTNHGGRQIDGGPAAFDSLQE
                     VAEAVDRRVPIVFDSGVRRGQHVFKALASGADLVAIGRPVIYGLALGGSVGVRQVFEH
                     LNAELKTVMQLSGAQTIEDVKHFKLRHNPYNPTFPVDPRDLKLY"
     regulatory      67688..67776
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            67991..68659
                     /locus_tag="ACL3EZ_000063"
     CDS             67991..68659
                     /locus_tag="ACL3EZ_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000449895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TenA family protein"
                     /protein_id="HGR0391715.1"
                     /translation="METQDYAFQPVLTVGELLKSSQKDWQAAINHRFVKELFAGTIEN
                     KVLKDYLIQDYHFFDAFLSMLGACVAHADKLESKLRFAKQLGFLEADEDGYFQKAFKE
                     LKVAENDYLEVTLHPVTKAFQDLMYWAVASSDYAHLLVMLVIAEGLYLDWGSKDLALP
                     EVYIHSEWINLHRGPFFAEWVQFLVDELNRVGKNREDLTELQQRWNQAVALELAFFDI
                     GYDV"
     gene            complement(68714..68845)
                     /locus_tag="ACL3EZ_000064"
     CDS             complement(68714..68845)
                     /locus_tag="ACL3EZ_000064"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0391716.1"
                     /translation="MKIKEQTRRLTAGCSKHCFEPVDKTDEVSSKHCFEVVDRTDVV"
     gene            68941..69723
                     /gene="thiM"
                     /locus_tag="ACL3EZ_000065"
     CDS             68941..69723
                     /gene="thiM"
                     /locus_tag="ACL3EZ_000065"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004417 - hydroxyethylthiazole kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HGR0391717.1"
                     /translation="MTSLKLLKEKAPLVICITNDVVKNFTANGLVALGASPAMSEFPA
                     DLEDLLKYAGGLLINIGTLTDENWKLYQAALKIAEKYNVPVVLDPVACGAGEYRKKVA
                     DDLINNYKLAAIRGNAGEIASLVGIDVASKGVDSAGVDNIDEIALAANEKFNIPIVVT
                     GEVDAIAVNGEVVTIHNGSAMMPKVIGTGCLLGAVVASFIGLEKGQELKSLETAMLVY
                     NIAGEMAEKRPNGHLPGTFKVEFINALYEITDEDVKEFKRVK"
     gene            69725..70354
                     /gene="thiE"
                     /locus_tag="ACL3EZ_000066"
     CDS             69725..70354
                     /gene="thiE"
                     /locus_tag="ACL3EZ_000066"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000468574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004789 - thiamine-phosphate
                     diphosphorylase activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HGR0391718.1"
                     /translation="MFHKELLKLYFICGTTTCQGKNLYTVVEEALKGGITLFQFREKG
                     EGALEGLEKLELAIQIKELCKKYNVPFIVNDDIDLAMEIDADGVHVGQDDIGVDEIRK
                     LMPDKIIGLSIRNEEEFQQSKVEYVDYVGVGPVFDTQSKDDAGGAIGYEGLELMRKLL
                     PQMPLVAIGGIQTKHIKDIIKTNMDGVSIISAISYAKNIEKTVREMSEQ"
     regulatory      70563..70651
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            70914..71474
                     /locus_tag="ACL3EZ_000067"
     CDS             70914..71474
                     /locus_tag="ACL3EZ_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HGR0391719.1"
                     /translation="MLKKWQLKDVILLAFLSIFFGGVFVGSGYVYNILSLLLTPLGLQ
                     AFANEILFGLWCMAAPIAAIFVPRVGSATIGEVLAALAEVLYGSQFGLGALLSGLVQG
                     LGSEFGFIVTKNRYESWLSLTANSIGITLVSFVYEYIKLGYYAFSLPFVLSLLVVRFI
                     SVYFFCTILVRAIVKLYHQFATGGKA"
     gene            71475..72860
                     /locus_tag="ACL3EZ_000068"
     CDS             71475..72860
                     /locus_tag="ACL3EZ_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGR0391720.1"
                     /translation="MGLELRAIQSPIFSEPFDFTFHAQAFTLLVGSSGSGKSSLFQMI
                     AQVSSLPYSGQVLIDGSEVSQLSIVERVQKVGILFQNPNHQFTMENLFEELIFTLENI
                     GYHLQEIDSKIAEVVQQCRCEAILHRPIHHLSGGEKQKAALAVLFAMNPRVYLLDEPF
                     ASIDRKSRIEILEILKELALDGKTVILCDHDLSDYKAYIDHMVELRDGKLREVFQIPS
                     YEMTQVASKEVASSPELFHMNRVTGELGNRPLFSIADFTFYQGISCILGDNGVGKSTL
                     FRSILQFQKYKGRIAWKGTVLKKKKSLYRDLTGIVQEAEKQFIRVSLREELQLDGPDS
                     ERNQRIFQALRYFDLEQAVDKSPYQLSGGQQKILQLLTILTSKASVILLDEPFAGLDD
                     RACHYFCKWIVEERNQGRSFLLISHRLDPLISVVDYWIEMTSQGLRHVKEVTITKPLT
                     SQSSNTQGEVR"
     gene            72862..73512
                     /locus_tag="ACL3EZ_000069"
     CDS             72862..73512
                     /locus_tag="ACL3EZ_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     component T"
                     /protein_id="HGR0391721.1"
                     /translation="MVKVATQTPIISLFLLILSLETSFIPSIALNLSVVAFCILFMLY
                     YRRFKMLAWMIILAILPSFANYWAVQLHGDASQAVMLGTRAFVTVCIGLVFVSSISLK
                     ELLLYLAQKGLSRSWSYALIVVFNSFPLIQQEIKSLKEACLLRGQELHFWSPLIYSKV
                     LMTVFRWRHLYLRALSAHGYDEHAQLKNSYRTFYIPKKTKLIYLLFFLLLQTSLFL"
     gene            73523..74215
                     /gene="tenA"
                     /locus_tag="ACL3EZ_000070"
     CDS             73523..74215
                     /gene="tenA"
                     /locus_tag="ACL3EZ_000070"
                     /EC_number="3.5.99.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050334 - thiaminase activity [Evidence
                     IEA];
                     GO_process: GO:0006772 - thiamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiaminase II"
                     /protein_id="HGR0391722.1"
                     /translation="MEFTDIAMELSKKAWQASFHHPFILQLQEGNLEPAIFRYYLIQD
                     AYYLKAFSEIYHLLADKTSNQEMKRLLKQNAQGLVEGELFIRQQFFKELEISDQEMEQ
                     HPIAPTCYHYISHIYRQFAEPNLAIAFASLLPCPWLYHDIGKSLNLKPSPNPLYQQWI
                     ETYITDELEQQIREEGALVNQLYRESDETDKQKMLDAFHISVHMEAKFWEMAYQHQTW
                     KSDLQSLEKGEE"
     gene            74220..74744
                     /gene="thiW"
                     /locus_tag="ACL3EZ_000071"
     CDS             74220..74744
                     /gene="thiW"
                     /locus_tag="ACL3EZ_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001225563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy coupling factor transporter S component
                     ThiW"
                     /protein_id="HGR0391723.1"
                     /translation="MRKHQLQVHKLTILSMMIALDVVLTPIFRIEGMAPMSSVVNILA
                     GIMMGPVYALAMATVTAFIRMTTQGIPPLALTGATFGALLAGLFYKYGRKFYFSALGE
                     IVGTGIIGSIVSYPVMVLFTGSATKLSWFIYTPRFFGATLIGTAISFIAFRFLIKQEF
                     FKKVQGYFFSERID"
     gene            74744..75547
                     /locus_tag="ACL3EZ_000072"
     CDS             74744..75547
                     /locus_tag="ACL3EZ_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HGR0391724.1"
                     /translation="MQEFTNPFPIGSSSLIHCMTNEISCEMLANGILALGCKPVMADD
                     PREVLDFTKQSQALFINLGHLSAEKEKAIRIAASYAAQVCLPMVVDAVGVTASSIRKS
                     LVRDLLDYRPTVLKGNMSEIRSLVGLKHHGVGVDASAKDQETEDLLQVLKDWCQTYHG
                     MSFLVTGPKDLVVSKNQVAVLGNGCAELDWITGTGDLVGALTAVFLSQGKTGFEASCL
                     AVSYLNIAAEKIVVQGMGLEEFRYQVLNQLSLLRRDENWLDTIKGEVYE"
     gene            75540..76172
                     /gene="thiE"
                     /locus_tag="ACL3EZ_000073"
     CDS             75540..76172
                     /gene="thiE"
                     /locus_tag="ACL3EZ_000073"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004789 - thiamine-phosphate
                     diphosphorylase activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HGR0391725.1"
                     /translation="MNREALRLYLVTNRYQDSVESFLAKVETACRSGVTIVQLREKNL
                     TTNQYYQLAKQVKEITDAYQVPLIIDDRLDVCLAVDAAGLHIGDDELPVSVARQVLGP
                     EKILGVTAKTVKRALEAEKSGADYLGTGAIFPTTTKENAPITLISTLKTICQTVAIPI
                     VAIGGLTSENIDQLMGTGIAGVAVVRDLMQAEDIEAKTQAFLTKLHDILS"
     gene            complement(76382..77173)
                     /gene="thiD"
                     /locus_tag="ACL3EZ_000074"
     CDS             complement(76382..77173)
                     /gene="thiD"
                     /locus_tag="ACL3EZ_000074"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008902 - hydroxymethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0008972 - phosphomethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HGR0391726.1"
                     /translation="MTYLPVALTIAGTDPSGGAGIMADLKSFQARDVYGMAVVTSLVA
                     QNTRGVQLIEHVSPQMLKAQLESVFSDIPPQAVKTGMLATTEIMEIIQPYLKKLDCPY
                     VLDPVMVATSGDALIDSSARDYLKTNLLPLATIITPNLPEAEEIVGFSIHDPEDMQRA
                     GRLILKEFGPQSVVIKGGHLKGGAKDFLFTKNEQFVWESPRIQTCHTHGTGCTFAAVI
                     TAELAKGKSLYQAVDKAKAFITKAIQDAPQLGHGSGPVNHTTFKD"
     regulatory      complement(77257..77355)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            77539..77934
                     /locus_tag="ACL3EZ_000075"
     CDS             77539..77934
                     /locus_tag="ACL3EZ_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0006825 - copper ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HGR0391727.1"
                     /translation="MQISDAEWQVMKIIWMQGEQTSTDLIRVLAERFDWSKSTVQTLL
                     ARLVEKECLTRKKEGKSFVYSALLTLDQSRDLLVQDIKDKVCSRRIRNLLADLIVECE
                     FTQTDLEDLEAVISEKKSSAVTEVRCNCM"
     gene            77945..78316
                     /locus_tag="ACL3EZ_000076"
     CDS             77945..78316
                     /locus_tag="ACL3EZ_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupredoxin domain-containing protein"
                     /protein_id="HGR0391728.1"
                     /translation="MLNSIVTIICIALIAFILFWFFKKPEKSGQKAQQKNGYQEIRVE
                     VMGGYTPELIVLKKSVPARIVFDRKDPSPCLDQIVFPDFGVHANLPMGEEYVVEITPE
                     QAGEFSFACGMNMMHGKMIVE"
     gene            78326..80569
                     /locus_tag="ACL3EZ_000077"
     CDS             78326..80569
                     /locus_tag="ACL3EZ_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042625 - ATPase-coupled ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HGR0391729.1"
                     /translation="MTEIVKASLENGIQKIRIQAEKGYHPAHIQLQKGIPAEITFHRA
                     TPSNCYKEILFEEEGILEPIGVDEEKVIRFTPQELGRHEFSCGMKMQKGSYTVVEKTR
                     KSLSLLQRFWITSICTVPLVILMIGMLAGSISHQVMHWGTFLATTPIMLVAGKPYIQS
                     AWASFKKHNANMDTLVALGTLVAYFYSLVALFAGLPVYFESAGFILFFVLLGAVFEEK
                     MRKNTSQAVEKLLDLQAKTAEVLSDDSYVQVPLEQVKVGDLIRVRPGEKIAVDGVVVE
                     GVSSIDESMVTGESLPVDKTVGDTVIGSTINHSGTLVFRAEKVGSETVLAQIVDFVKK
                     AQISRAPIQDLTDKISGIFVPVVVILGIMTFWVWFVLLRDSVVVLGASFVSSLLYGVA
                     VLIIACPCALGLATPTALMVGTGRSAKMGVLLKNGTVLQEIQKVQTLVFDKTGTLTEG
                     KPVVTDVIGDEVEVFGLAASLEDASQHPLAEAIVKRASEAGLEFQTVENFQALHGKGV
                     SGRINGKQVLLGNAKMLDGMDISNTYQDKLEELEKEAKTVVFLAVDNEIKGLLALQDI
                     PKKNAKLAISQLKKRGLGTVMLTGDNAGVARAIADQIGIEEVIAGVLPEEKAHEIHKL
                     QQSGKVAFVGDGINDAPALSVADVGIAMGAGTDIAIESADLVLTTNNLLGVVRAFDMS
                     KKTFHRILLNLFWAFIYNVVGIPIAAGVFSGVGLALNPELAGLAMAFSSVSVLTSSLL
                     LNFSKID"
     gene            80776..82551
                     /gene="spxB"
                     /locus_tag="ACL3EZ_000078"
     CDS             80776..82551
                     /gene="spxB"
                     /locus_tag="ACL3EZ_000078"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047112 - pyruvate oxidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HGR0391730.1"
                     /translation="MTQGKITASAAMLNVLKTWGVDTIYGIPSGTLSSLMDALAEDKD
                     IRFLQVRHEETGALAAVMQAKFGGSIGVAVGSGGPGATHLINGVYDAAMDNTPFLAIL
                     GSRPVNELNMDAFQELNQNPMYNGIAVYNKRVAYAEQLPKVIDEACRAAVSKKGPAVV
                     EIPVNFGFQEIDENSYYGSGSYERSFIAPALNEVEIDKAVEILNNAERPVIYAGFGGV
                     KAGEVITELSRKIKAPIITTGKNFEAFEWNYEGLTGSAYRVGWKPANEVVFEADTVLF
                     LGSNFPFAEVYEAFKNTEKFIQVDIDPYKLGKRHALDASILGDAGQAAKAILDKVNPV
                     ESTPWWRANVKNNQNWRDYMNKLEGKTEGELQLYQVYNAINKHADQDAIYSIDVGNTT
                     QTSTRHLHMTPKNMWRTSPLFATMGIALPGGIAAKKDNPDRQVWNIMGDGAFNMCYPD
                     VITNVQYDLPVINLVFSNAEYGFIKNKYEDTNKHLFGVDFTNADYAKIAEAQGAVGFT
                     VDRIEDIDAVVAEAVKLNKEGKTVVIDARITQHRPLPVEVLELDPKLHSEEAIKAFKE
                     KYEAEELVPFRLFLEEEGLQSRAIK"
     gene            82662..83009
                     /locus_tag="ACL3EZ_000079"
     CDS             82662..83009
                     /locus_tag="ACL3EZ_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003017645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HGR0391731.1"
                     /translation="MNLNQLDIIVSNVPQVCADLEHILDKKADYADDGFAQFTIGSHC
                     LMLSQNHLVPLENFQSGIIIHIEVEDVDQNYKRLNELGIKVLHGPTVTDWGTESLLVQ
                     GPAGLVLDFYRMK"
     gene            complement(83126..84127)
                     /locus_tag="ACL3EZ_000080"
                     /pseudo
     CDS             complement(83126..84127)
                     /locus_tag="ACL3EZ_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            84423..84728
                     /locus_tag="ACL3EZ_000081"
                     /pseudo
     CDS             84423..84728
                     /locus_tag="ACL3EZ_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884744.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
     gene            84860..85804
                     /gene="manA"
                     /locus_tag="ACL3EZ_000082"
     CDS             84860..85804
                     /gene="manA"
                     /locus_tag="ACL3EZ_000082"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004476 - mannose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HGR0391732.1"
                     /translation="MSEPLFLQSVMQEKIWGGTKLRDEFGYDIPSEKVGEYWAISAHL
                     NGVSKVANGRYEGTDLATLYAEHRELFGNRPEPVFPLLTKILDANDWLSVQVHPDDAY
                     GLEHEGELGKTECWYIIAADEGSEIIYGHNAKSKEELRQQIEDKNWDALLTKVPVKAG
                     DFFYVPSGTMHAIGAGILILETQQSSDTTYRVYDFDRKDDKGNLRELHLEKSIDVLNI
                     GEPANSRPVTIKADDLRSTLLVSNDFFAVYKWEITGKVNFEKTADYSLLSVLAGQGQL
                     TVDGKNYPIQKGRHFILPSDVEAWTLEGQDLELIVSHP"
     gene            complement(85826..87301)
                     /locus_tag="ACL3EZ_000083"
     CDS             complement(85826..87301)
                     /locus_tag="ACL3EZ_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-dependent transporter"
                     /protein_id="HGR0391733.1"
                     /translation="MVFLTDLRKHNRIVKSINQTEGYLTTQVAFSYFEKGDQSLTMSE
                     KSQWGSKLGFILASAGSVIGLGSVWKFPYMTAANGGGGFLLIFLISTILIGFPLLLAE
                     FALGRSAGVSAIKTFGKLGKNNKYNFIGWIGAFALFILLSFYSVIGGWILVYLGIEFG
                     KLFQLGGTGDYAQLFTSIISNPAIALGAQAAFILLNIFIVSRGVQKGIERASKVMMPL
                     LFIIFVVIIGRSLSLPNAMEGVLYFLKPDFSKLTSAGLLYALGQSFFALSLGVTVMLT
                     YASYLDKKTNLVQSGISIVAMNISISIMAGLAIFQARSPFNIQSEGGPSLLFIVLPQL
                     FDKMPFGTIFYVLFLFATVTSSVVMLEINVGNITNQDNSKRAKWSVILGILTFVFGIP
                     SALSYGVMADVHIFGKTFFDAMNFLVPNLLMPFGALYLSLFTGYIFKKALAMEELHLD
                     ERAWKQGLFQVWLFLLRFFVPSFQSSSWSSSPNLCNQKGLE"
     gene            87384..88138
                     /locus_tag="ACL3EZ_000084"
                     /pseudo
     CDS             87384..88138
                     /locus_tag="ACL3EZ_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000274794.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
     gene            complement(88158..88613)
                     /locus_tag="ACL3EZ_000085"
     CDS             complement(88158..88613)
                     /locus_tag="ACL3EZ_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HGR0391734.1"
                     /translation="MNRREAVEFVNMCMIKNGDKVLVQDRVSPDWSGITFPGGHVERG
                     ESFVDAVIREVKEETGLIISKPQLCGIKNWYDDKDYRYVVLFYKTEHFTGELQSSDEG
                     KVWWEDFENLSHLKLATDDMSDMLRVFLEEDLSEFFYYKNGDDWLYDLK"
     gene            complement(88633..89808)
                     /locus_tag="ACL3EZ_000086"
     CDS             complement(88633..89808)
                     /locus_tag="ACL3EZ_000086"
                     /EC_number="1.14.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HGR0391735.1"
                     /translation="MKHFDTIVIGGGPAGMMATISSSFYGQKTLLIEKNRKLGKKLAG
                     TGGGRCNVTNNGSLDNLLAGIPGNGRFLYSVFSQFDNHDIINFFTENGVKLKVEDHGR
                     VFPASDKSRTIIEALEKKITELGGQVATQIEIVSVKKVDDQFVLKSADQTFTCEKLIV
                     TTGGKSYPSTGSTGFGHEIARHFKHTITDLEAAESPLLTDFPHKALQGISLDDVTLSY
                     GKHVITHDLLFTHFGLSGPAALRMSSFVKGGEVLSLDVLPQLSEKDLVTFLEENREKS
                     LKNALKTLLPERLAEFFVQGYPEKVKQLTEKEREQLVQSIKELKIPVTGKMSLAKSFV
                     TKGGVSLKEINPKTLESKLVPGLHFAGEVMDINAHTGGFNITSALCTGWVAGSLHYD"
     gene            complement(89867..90712)
                     /locus_tag="ACL3EZ_000087"
     CDS             complement(89867..90712)
                     /locus_tag="ACL3EZ_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HGR0391736.1"
                     /translation="MTWKIIADSGCDYRQLPTPAINTTFVSVPLTIQVADQVFVDDAS
                     LDIDQMMETMYATAEASKSACPSPDDYLRAFEGAKNIFLVTITGTLSGSHNSAQLAKN
                     IYLEDHPDTKIHVIDSLSAGGEVDLLVEKLNDLIDQGLSFEEVVEAITAYQEKTKLLF
                     VLAKVDNLVKNGRLSKLIGTVVGLLNIRMVGKASETGTLELLQKARGSKKSVQAAYDE
                     LVKAGYAGGRIVMAQRNNEKCCQQLSERIRETFPQADIKILPTSGLCSFYAEEGGLLM
                     GYEID"
     gene            90837..91394
                     /locus_tag="ACL3EZ_000088"
     CDS             90837..91394
                     /locus_tag="ACL3EZ_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HGR0391737.1"
                     /translation="MSERRISEKSLENLRKSNQESNLLTREAIETALLQLLEKKELTK
                     ISISELVKRAGVSRAAFYRNYDSKEEILESVFKRTVHNIMEQLHHYDLKTDLYLVWVH
                     LFREARKEARVIQLALDYHLEKIFVQAMQEFLEKYHGKSKGVSSYLHSFWSSAIVSVL
                     LKWIKDGMKVPAEKIADLGLPFFKK"
     gene            91413..91880
                     /locus_tag="ACL3EZ_000089"
     CDS             91413..91880
                     /locus_tag="ACL3EZ_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000138511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine/deoxycytidylate deaminase family
                     protein"
                     /protein_id="HGR0391738.1"
                     /translation="MTEKRLAWDEYFAAQALLIANRSTCKRAKVGAILVKDNKVISTG
                     YNGSVSGTEHCIDHECLVIEGHCVRTLHAEVNAILQGAERGVPKGFTAYVTHFPCLNC
                     TKQLLQVGCKRVVYINQYRMDDYAQYLYQEKGTELTHLPLETVQTALKEADLM"
     gene            91969..92598
                     /gene="upp"
                     /locus_tag="ACL3EZ_000090"
     CDS             91969..92598
                     /gene="upp"
                     /locus_tag="ACL3EZ_000090"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004845 - uracil phosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HGR0391739.1"
                     /translation="MGKIEVINHPLIQHKLSILRRTDTSTKAFRELVDEIAMLMGYEV
                     LRDLPLEDVEIETPITKTVQKQLAGKKLAIVPILRAGIGMVDGLLSLVPAAKVGHIGM
                     YRDEETLQPVEYLVKLPEDIDQRQIFIVDPMLATGGSAILAVDSLKKRGASNIKFVCL
                     VSAPEGVKALQEAHPDVEIFTAALDERLNEHGYIVPGLGDAGDRLFGTK"
     gene            92772..93362
                     /gene="clpP"
                     /locus_tag="ACL3EZ_000091"
     CDS             92772..93362
                     /gene="clpP"
                     /locus_tag="ACL3EZ_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit
                     ClpP"
                     /protein_id="HGR0391740.1"
                     /translation="MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIA
                     QLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIA
                     SSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQ
                     SMEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN"
     gene            93441..93689
                     /locus_tag="ACL3EZ_000092"
     CDS             93441..93689
                     /locus_tag="ACL3EZ_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HGR0391741.1"
                     /translation="MFEKVNRSGLIIYLYYNRDAKKLQDYGDITYHSKKHRYLQLYVP
                     TQEVEQLVGRLSKEKFIKKVRVCHIQELETPFVGNLYR"
     gene            93790..94950
                     /locus_tag="ACL3EZ_000093"
     CDS             93790..94950
                     /locus_tag="ACL3EZ_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGR0391742.1"
                     /translation="MKKKFALSFVALASVALLAACGEVKSGAVNTAGNSVEEKTIKIG
                     FNFEESGSLAAYGTAEQKGAQLAVDEINAAGGIDGKQIEVVDKDNKSETAEAASVTTN
                     LVTQSKVSAVVGPATSGATAAAVANATKAGVPLISPSATQDGLTKGQDYLFIGTFQDS
                     FQGKIISNYVSEKLNAKKVVLYTDNASDYAKGIAKSFRESYKGEIVADETFVAGDTDF
                     QAALTKMKGKDFDAIVVPGYYNEAGKIVNQARGMGIDKPIVGGDGFNGEEFVQQATAE
                     KASNIYFISGFSTTVEVSAKAKAFLDAYRAKYNEEPSTFAALAYDSVHLVANAAKGAK
                     NSGEIKDNLAKTKDFEGVTGQTSFDADHNTVKTAYMMTMNNGKVEAAEVVKP"
     gene            95218..96087
                     /locus_tag="ACL3EZ_000094"
     CDS             95218..96087
                     /locus_tag="ACL3EZ_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0015658 - branched-chain amino acid
                     transmembrane transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HGR0391743.1"
                     /translation="MLQQLVNGLILGSVYALLALGYTMVYGIIKLINFAHGDIYMMGA
                     FIGYFLINSFQMNFFVALIVAMLATAILGVVIEFLAYRPLRHSTRIAVLITAIGVSFL
                     LEYGMVYLVGANTRAFPQAIQTVRYDLGPISLTNVQLMILAISLILMILLQVIVQKTK
                     MGKAMRAVSVDSDAAQLMGINVNRTISFTFALGSALAGAAGVLIALYYNSLEPLMGVT
                     PGLKSFVAAVLGGIGIIPGAALGGFVIGLLETFATAFGMSDFRDAIVYGILLLILIVR
                     PAGILGKNVKEKV"
     gene            96091..97047
                     /locus_tag="ACL3EZ_000095"
     CDS             96091..97047
                     /locus_tag="ACL3EZ_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HGR0391744.1"
                     /translation="MKENLKVNILWLLLLLAGYSLISVLVSVGVLNLFYVQILQQIGI
                     NIILAVGLNLIVGFSGQFSLGHAGFMAIGAYAAAIIGSKLPTYGAFFGAMLVGALLSG
                     AVALLVGIPTLRLKGDYLAVATLGVSEIIRIFIINGGSLTNGAAGILGIPNFTTWQMV
                     YFFVVITTIATLNFLRSPIGRSTLSVREDEIAAESVGVNTTKIKIIAFVFGAITASIA
                     GSLQAGFIGSVVPKDYTFINSINVLIIVVFGGLGSITGAIVSAIVLGILNMLLQDVAS
                     VRMIIYALALVLVMIFRPGGLLGTWELSLSRFFKKSKKEEQN"
     gene            97047..97811
                     /locus_tag="ACL3EZ_000096"
     CDS             97047..97811
                     /locus_tag="ACL3EZ_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0391745.1"
                     /translation="MALLEVKQLTKHFGGLTAVGDVTLELNEGELVGLIGPNGAGKTT
                     LFNLLTGVYEPSEGTVTLDGHLLNGKSPYKIASLGLGRTFQNIRLFKDLTVLDNVLIA
                     FGNHHKQHVFTSFLRLPAFYKSEKELKAKALELLKIFDLDGDAETLAKNLSYGQQRRL
                     EIVRALATEPKILFLDEPAAGMNPQETAELTELIRRIKDEFKITIMLIEHDMNLVMEV
                     TERIYVLEYGRLIAQGTPDEIKTNKRVIEAYLGGEA"
     gene            97811..98521
                     /locus_tag="ACL3EZ_000097"
     CDS             97811..98521
                     /locus_tag="ACL3EZ_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000062217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0391746.1"
                     /translation="MSMLKVENLSVHYGMIQAVRDVSFEVNEGEVVSLIGANGAGKTT
                     ILRTLSGLVRPSSGKIEFLGQEIQKMPAQKIVAGGLSQVPEGRHVFPGLTVMENLEMG
                     AFLKKNREENQANLKKVFSRFPRLEERKNQDAATLSGGEQQMLAMGRALMSTPKLLLL
                     DEPSMGLAPIFIQEIFDIIQDIQKQGTTVLLIEQNANKALAISDRGYVLETGKIVLSG
                     TGKELASSEEVRKAYLGG"
     gene            98935..99591
                     /locus_tag="ACL3EZ_000098"
     CDS             98935..99591
                     /locus_tag="ACL3EZ_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HGR0391747.1"
                     /translation="MAVKDFMTRKVVYISPDTTVSHAADLMREQGLHRLPVIENDQLV
                     GLVTEGTIAQASPSKATSLSIYEMNYLLNKTKVKDVMIRDVVTVSGYASLEDATYLML
                     KNKISILPVVDNHQVYGVITDRDVFQAFLEIAGYGEEGIRVRFVTEDEVGVLGKIVSL
                     IVEENLNISHTVNIPRKDGKVIIEVQIDGSIDLPALKEKFEANGIQVEEIARTSAKVL
                     "
     gene            99699..100794
                     /gene="prfB"
                     /locus_tag="ACL3EZ_000099"
     CDS             join(99699..99770,99772..100794)
                     /gene="prfB"
                     /locus_tag="ACL3EZ_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511312.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0016149 - translation release factor
                     activity, codon specific [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HGR0391748.1"
                     /translation="MDISVIRQKIDANREKLASFRGSLDLEGLEEEIAILENKMTEPD
                     FWNDNIAAQKTSQELNELKNTYNTFHKMEELQDEVEILLDFLAEDESVHDELVAQLAE
                     LDKIMTSYEMTLLLSEPYDHNNAILEIHPGSGGTEAQDWGDMLLRMYTRYGNAKGFKV
                     EVLDYQAGDEAGIKSVTLSFEGPNAYGLLKSEMGVHRLVRISPFDSAKRRHTSFTSVE
                     VMPELDDTIEVEIREDDIKMDTFRSGGAGGQNVNKVSTGVRLTHIPTGIVVQSTVDRT
                     QYGNRDRAMKMLQAKLYQMEQEKKAAEVDSLKGEKKEITWGSQIRSYVFTPYTMVKDH
                     RTSFEVAQVDKVMDGDLDGFIDAYLKWRIS"
     gene            100812..101504
                     /gene="ftsE"
                     /locus_tag="ACL3EZ_000100"
     CDS             100812..101504
                     /gene="ftsE"
                     /locus_tag="ACL3EZ_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HGR0391749.1"
                     /translation="MSIIEMRDVVKKYDNGTTALRGVSVSVQPGEFAYIVGPSGAGKS
                     TFIRSLYREVKIDKGSLSVAGFNLVKIKKKDIPLLRRSVGVVFQDYKLLPKKTVYENI
                     AYAMEVIGENRRNIKRRVMEVLDLVGLKHKVRSFPNELSGGEQQRIAIARAIVNNPKV
                     LIADEPTGNLDPDNSWEIMNLLERINLQGTTILMATHNSQIVNTLRHRVIAIENGRVV
                     RDESKGEYGYDD"
     gene            101497..102423
                     /gene="ftsX"
                     /locus_tag="ACL3EZ_000101"
     CDS             101497..102423
                     /gene="ftsX"
                     /locus_tag="ACL3EZ_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="permease-like cell division protein FtsX"
                     /protein_id="HGR0391750.1"
                     /translation="MISRFFRHLFEALKSLKRNGWMTVAAVSSVMITLTLVAIFASVI
                     FNTAKLATDIENNVRVVVYIRKDVEDNSQTIEKEGQTVTNNDYHKVYDSLKNMSTVKS
                     VTFSSKEEQYEKLTEIMGDNWKIFEGDANPLYDAYIVEANTPNDVKTIAEDAKKIEGV
                     SEVQDGGANTERLFKLASFIRVWGLGIAALLIFIAVFLISNTIRITIISRSREIQIMR
                     LVGAKNSYIRGPFLLEGAFIGLLGAIAPSVLVFIVYQIVYQSVNKSLVGQNLSMISPD
                     LFSPLMIALLFVIGVFIGSLGSGISMRRFLKV"
     gene            102709..104889
                     /locus_tag="ACL3EZ_000102"
     CDS             102709..104889
                     /locus_tag="ACL3EZ_000102"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000974069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015144 - carbohydrate transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIBC"
                     /protein_id="HGR0391751.1"
                     /translation="MMKDTFKNVLSFEFWQKFGKALMVVIAVMPAAGLMISIGKSIVM
                     INPTFAPLVITGGILEQIGWGVIGNLHILFALAIGGSWAKERAGGAFAAGLAFILINR
                     ITGTIFGVSGDMLKNPDAMVTTFFGGSIKVADYFISVLEAPALNMGVFVGIISGFVGA
                     TAYNKYYNFRKLPDALSFFNGKRFVPFVVILRSAIAAILLAAFWPVVQTGINNFGIWI
                     ANSQETAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYDILTGAAKGTQVFG
                     QDPLWLAWVTDLVNLKGTDASQYQHLLDTVHPARFKVGQMIGSFGILMGVIVAIYRNV
                     DADKKHKYKGMMIATALATFLTGVTEPIEYMFMFIATPMYLVYSLVQGAAFAMADVVN
                     LRMHSFGSIEFLTRTPIAISAGIGMDIVNFVWVTVLFAVIMYFIANFMIQKFNYATPG
                     RNGNYETAEGSEETSSEVKVAAGSQAVNIINLLGGRVNIVDVDACMTRLRVTVKDADK
                     VGNAEQWKAEGAMGLVMKGQGVQAIYGPKADILKSDIQDILDSGEIIPETLPSQMTEA
                     QQNTVHFKDLTEEVYSVADGQVVALEQVKDPVFAQKMMGDGFAVEPANGNIVSPVSGT
                     VSSIFPTKHAFGIVTEAGLEVLVHIGLDTVSLEGKPFTVHVAEGQKVAAGDLLVTADL
                     DAIRAAGRETSTVVVFTNGDAIKSVKLEKTGSLAAKTAVAKVEL"
     gene            104941..105756
                     /locus_tag="ACL3EZ_000103"
     CDS             104941..105756
                     /locus_tag="ACL3EZ_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HGR0391752.1"
                     /translation="MKFLTLNTHSWMEKEAEEKFQILLEDILEKDYDLICFQEINQEM
                     TSSEVEVNDLYQALPAAEPIHQDHYVRLLVEKLLEQGKNYYWTWAYNHIGYDRYHEGV
                     AILSKTPIEAREILVSDVDDPTDYHTRRVALAETVVDGKELAVASVHLSWWDKGFQEE
                     WARFEAVLKKLNKPLLLAGDFNNPAGQEGYQAILASPLGLQDAFEVAQEKSGSYTVPP
                     EIDGWKGNTEPLRIDYVFTTKELAVENLHVVFDGNKSPQVSDHYGLNAILNWK"
     gene            105896..107239
                     /locus_tag="ACL3EZ_000104"
     CDS             105896..107239
                     /locus_tag="ACL3EZ_000104"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HGR0391753.1"
                     /translation="MSFTKFQFKNYIREALKELKFTTPTEVQDKLIPIVLAGRDLVGE
                     SKTGSGKTHTFLLPIFQQLDEASDSVQAVITAPSRELATQIYQVARQISAHSDVEVRV
                     VNYVGGTDKARQIEKLESNQPHIVIGTPGRIYDLVKSGDLAIHKAKTFVVDEADMTLD
                     MGFLETVDKIAGSLPKDLQFMVFSATIPQKLQPFLKKYLSNPVMEKIKTKTVISDTID
                     NWLISTKGHDKNAQIYQLTQLMQPYLAMIFVNTKTRADELHSYLTAQGLKVAKIHGDI
                     APRERKRIMNQVQNLDFEYIVATDLAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTG
                     RNGLPGTAITLYQPSDDSDIRELEKLGIKFSPKMVKDGEFQDTYDRDRRANREKKQDK
                     LDIEMIGLVKKKKKKVKPGYKKKIQWAVDEKRRKTKRAENRARGRAERKAKRQTF"
     gene            107454..108644
                     /gene="metK"
                     /locus_tag="ACL3EZ_000105"
     CDS             107454..108644
                     /gene="metK"
                     /locus_tag="ACL3EZ_000105"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004478 - methionine adenosyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006556 - S-adenosylmethionine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HGR0391754.1"
                     /translation="MSERKLFTSESVSEGHPDKIADQISDAILDAILAKDPEAHVAAE
                     TAVYTGSVHVFGEISTNAYVDINRVVRDTIAEIGYTNTEYGFSAETVGVHPSLVEQSP
                     DIAQGVNEALEVRGNADQDPLDLIGAGDQGLMFGFAVDETEELMPLPIALSHKLVRRL
                     AELRKSGEISYLRPDAKSQVTVEYDENDRPVRVDTVVISTQHDPEATNEQIHQDVINK
                     VIKEVIPSSYLDDKTKFFINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLAKKAEVQLAYAIGVAQPVSVRIDTFGTGTVA
                     ESQLEKAARQIFDLRPAGIIQMLDLKRPIYRQTSAYGHMGRTDIDLPWERLDKVDALK
                     EAVK"
     gene            109197..110132
                     /locus_tag="ACL3EZ_000106"
     CDS             109197..110132
                     /locus_tag="ACL3EZ_000106"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004152 - dihydroorotate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HGR0391755.1"
                     /translation="MVSTKTQIAGFEFDNCLMNAAGVACMTIEELEEVKNSAAGTFVT
                     KTATLDFRQGNPEPRYQDVPLGSINSMGLPNNGLDYYLDYLLDLQEKESNRTFFLSLV
                     GMSPEETHTILKKVQESDFRGLTELNLSCPNVPGKPQIAYDFETTDRILAEVFAYFTK
                     PLGIKLPPYFDIVHFDQAAAIFNKYPLKFVNCVNSIGNGLYIEDESVVIRPKNGFGGI
                     GGEYIKPTALANVHAFYQRLNPQIQIIGTGGVLTGRDAFEHILCGASMVQVGTTLHKE
                     GVSAFDRITNELKAIMVEKGYESLEDFRGKLRYID"
     gene            110166..111203
                     /gene="holA"
                     /locus_tag="ACL3EZ_000107"
     CDS             110166..111203
                     /gene="holA"
                     /locus_tag="ACL3EZ_000107"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HGR0391756.1"
                     /translation="MLAIEESQKLTLSNLPSLSLFTGTDQGQFEVMKSQVLKQIGYDS
                     ADLNFAYFDMKEVVYKDVELELVSLPFFADEKIVILDYFMDITTAKKRFLTDDELKSF
                     EEYLDNPSPTTKLIIFAEGKLDSKRRLVKLLKRDAKAFDAVEVKEQELRQYFQKWSQK
                     QGLQFTNHSFENLLIKSGFQFSEIQKNLLFLQSYKADSVIEEEDIVNAIPKTLQDNIF
                     DLTQFILTKKMDQARDLVRDLTLQGEDEIKLIAVMLGQFRTFTQVKILAESGQTESQI
                     ASSLGSYLGRNPNPYQIKFALRDSRGLSLSFLKQAISYLIETDYQIKTGLYEKGFLFE
                     KALLQIASQVN"
     gene            111344..111949
                     /gene="sodA"
                     /locus_tag="ACL3EZ_000108"
     CDS             111344..111949
                     /gene="sodA"
                     /locus_tag="ACL3EZ_000108"
                     /EC_number="1.15.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004784 - superoxide dismutase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase SodA"
                     /protein_id="HGR0391757.1"
                     /translation="MAIILPELPYAYDALEPYIDAETMHLHHDKHHQTYVNNANAALE
                     KHPEIGEDLEALLADVESIPADIRQALINNGGGHLNHALFWELMTPEKTAPSAELAAA
                     IDATFGSFEEFQAAFTAAATTRFGSGWAWLVVNKEGKLEVTSTANQDTPISEGKKPIL
                     GLDVWEHAYYVKYRNVRPDYIKAFFSVINWNKVDELYAAAK"
     gene            112107..112637
                     /locus_tag="ACL3EZ_000109"
     CDS             112107..112637
                     /locus_tag="ACL3EZ_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HGR0391758.1"
                     /translation="MRKEIAPELYNYNKFPGPEFHLHGDKVETEGIAFSLVENIKDAF
                     DVTTFNQRFSEVLTKFDYIVGDWSNEQLRLRGFYKDDRTEEKLEKISRLQDYLLEYCS
                     YGCAYFVLENEAPKRASFDKKMRKTEEETPSRKGKKPTQTKRKSNADKKNRRRQKDQH
                     SQKEDKEQRHFVIRQK"
     gene            112658..113560
                     /gene="rlmN"
                     /locus_tag="ACL3EZ_000110"
     CDS             112658..113560
                     /gene="rlmN"
                     /locus_tag="ACL3EZ_000110"
                     /EC_number="2.1.1.192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0002935 - tRNA
                     (adenine(37)-C2)-methyltransferase activity [Evidence
                     IEA];
                     GO_function: GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:0070040 - rRNA
                     (adenine(2503)-C2-)-methyltransferase activity [Evidence
                     IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0030488 - tRNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HGR0391759.1"
                     /translation="MKPSIHSLVHQTMQEWVLEQGEKKFRADQIWEWLYRKRVQSFEE
                     MTNLSKDLIAKLNDQFVVNPLKQRIVQESADGTVKYLFELPDGMLIETVLMRQHYGLS
                     VCVTTQVGCNIGCTFCASGLIKKQRDLNNGEIVAQIMLVQKYFADEGVQVNLAVSLHA
                     PNNELRSSIMKINRAFPIEKLFAAIEYYIETTNRRVTFEYIMLNEVNDGVEQALELAE
                     LLKNIKKLSYVNLIPYNPVSEHDQYSRSPKERVLAFYDTLKKKGVNCVVRQEHGTDID
                     AACGQLRSNTMKRDRQKAVAAVNP"
     gene            113560..114042
                     /locus_tag="ACL3EZ_000111"
     CDS             113560..114042
                     /locus_tag="ACL3EZ_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000976721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HGR0391760.1"
                     /translation="MMKKTYNHILVWGVIFYSICIVCFCFTPQEQSTVGVGTPGIQHL
                     GRLVFLLTPFNSLWKLGEVSDIGQLCWIFLQNVLNVFLFFPLIFQLLYLFPNLRKTKK
                     VLLFSFLVSLGIECTQLILDFFFDFNRVFEIDDLWTNTLGGYLAWLLYKRLHKNKIRN
                     "
     gene            114044..115585
                     /locus_tag="ACL3EZ_000112"
     CDS             114044..115585
                     /locus_tag="ACL3EZ_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002918612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HGR0391761.1"
                     /translation="MSILEVKNLSHGFGDRAIFEDVSFRLLKGEHIGLVGANGEGKST
                     FMSIVTGKMLPDEGKVEWSKYVTAGYLDQHSVLAERQSVRDVLRTAFDELFKAEARIN
                     DLYMKMAEDGADVDALMEEVGELQDRLESRDFYTLDAKIDEVARALGVMDFGMDTDVT
                     SLSGGQRTKVLLAKLLLEKPDILLLDEPTNYLDAEHIDWLKRYLQNYENAFVLISHDI
                     PFLNDVINIVYHVENQQLTRYSGDYYQFQEVYAMKKSQLEAAYERQQKEIADLKDFVA
                     RNKARVATRNMAMSRQKKLDKMDIIELQSEKPKPSFDFKPARTPGRFIFQAKNLQIGY
                     DRPLTKPLNLTFERNQKVAIIGANGIGKTTLLKSLLGIISPIAGEVERGDYLELGYFE
                     QEVEGGNRQTPLEAVWNAFPALNQAEVRAALARCGLTTKHIESQIQVLSGGEQAKVRF
                     CLLMNRENNVLVLDEPTNHLDVDAKDELKRALKEYRGSILMVCHEPDFYEGWIDQIWD
                     FNNLT"
     gene            complement(115640..116896)
                     /locus_tag="ACL3EZ_000113"
     CDS             complement(115640..116896)
                     /locus_tag="ACL3EZ_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element IS1167A family transposase"
                     /protein_id="HGR0391762.1"
                     /translation="MEQLHFITKLLDIKDPNIKILDIINMDTHKEIIAKLDYEAPSCP
                     DCGSLMKKYDFQKPSKIPYLETTGMPSRILLRKRRFKCYHCSKMMVAETPLVKKNHQI
                     PRIINQKIAQKLIEKISMTDIAHQLAISTSTVIRKLNDFHFEHDFSRLPKIMSWDEYA
                     FTKGKMSFIAQDFDNLNIITVLEGRTQAVIRNHFLRYDRAVRCQVKIITMDMFSPYYD
                     LAKQLFPCAKIVLDRFHIIQHLSRAMSRFRVQIMNQFERKSHEYKAIKRYWKLIQQDS
                     RKLSDKRFYRPTFRMHLTNKEILDKILSYSEDLKHHYQIYQLLLFHFQNKDPEKFFGL
                     IEDNLKQVHPIFQTVFKTFLKNKEKIVNALQLPYSNAKLEATNNLIKLIKRNAFGFRN
                     FENFKKRIFIALNIKKERTNFVLSRA"
     gene            complement(117063..117866)
                     /locus_tag="ACL3EZ_000114"
     CDS             complement(117063..117866)
                     /locus_tag="ACL3EZ_000114"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HGR0391763.1"
                     /translation="MKKLATLLLLSTVALAGCSSVQRSLRGDDYVDSSLAAEESSKVA
                     AQSAKELNDALTNENANFPQLSKEVAEDEAEVILHTSQGDIRIKLFPKLAPLAVENFL
                     THAKEGYYNGITFHRVIDGFMVQTGDPKGDGTGGQSIWHDKDKTKDKGTGFKNEITPY
                     LYNIRGALAMANTGQPNTNGSQFFINQNSTDTSSKLPTSKYPQKIIEAYKEGGNPSLD
                     GKHPVFGQVIDGMDVVDKIAKAEKDEKDKPTTAITIDSIEVVKDYDFKS"
     gene            complement(117950..118171)
                     /locus_tag="ACL3EZ_000115"
     CDS             complement(117950..118171)
                     /locus_tag="ACL3EZ_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0391764.1"
                     /translation="MSFYGLFYNGIAITPNTYLSAWFVNFIAALPLNFLIVEPIARFI
                     LSSFQKPFTGEEVEEVEDFQDDDEIPTII"
     gene            complement(118650..118859)
                     /locus_tag="ACL3EZ_000116"
     CDS             complement(118650..118859)
                     /locus_tag="ACL3EZ_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000953868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0391765.1"
                     /translation="MLSVNTILEKFYKEHQVKPFISPERELDTWLLSPKPVPKRNMDL
                     LVDDSLAGDIILLWRIQFGTFTTET"
     gene            119029..119301
                     /gene="rpsP"
                     /locus_tag="ACL3EZ_000117"
     CDS             119029..119301
                     /gene="rpsP"
                     /locus_tag="ACL3EZ_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HGR0391766.1"
                     /translation="MAVKIRLTRMGSKKKPFYRINVADSRSPRDGRFIETVGTYNPLV
                     AENQVTLKEDRVLAWLANGAQPSDTVRNILSKEGVLKKFHDSKFSK"
     gene            119321..119560
                     /gene="kphA"
                     /locus_tag="ACL3EZ_000118"
     CDS             119321..119560
                     /gene="kphA"
                     /locus_tag="ACL3EZ_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein KphA"
                     /protein_id="HGR0391767.1"
                     /translation="MDTIENLIIAIVKPLISQPDALTIKIEDTPEFLEYHLNLDQSDV
                     GRVIGRKGRTISAIRTIVYSVPTEYKKVRIVIDEK"
     gene            119709..120023
                     /locus_tag="ACL3EZ_000119"
                     /pseudo
     CDS             119709..120023
                     /locus_tag="ACL3EZ_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000654120.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
     gene            120127..120915
                     /locus_tag="ACL3EZ_000120"
     CDS             120127..120915
                     /locus_tag="ACL3EZ_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HGR0391768.1"
                     /translation="MKRFEVSTEIGSLSVTYQKQKKVLVCLNGAGLLPSYENFSLILE
                     KPPPTIGYLTIDFPNTGRSPIHDQAGKNLDNLADVVYEVLEELGISEYILCAHSWSGI
                     LACKLLEKPIKCQTLVAIEPTTKKVMFADFSENPYPEMEEQMRLIDECGPELYFKNLT
                     QATFSPETNKKIWELMQEKGLELENQDPEFQISGEITEEDFENLSIESHVPVFIFCQT
                     YREKEYRESEYWTSNTKLILGGNHHYLQWSESEKIAAIIRELSE"
     gene            120946..121464
                     /gene="rimM"
                     /locus_tag="ACL3EZ_000121"
     CDS             120946..121464
                     /gene="rimM"
                     /locus_tag="ACL3EZ_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465641.1"
                     /note="Essential for efficient processing of 16S rRNA;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HGR0391769.1"
                     /translation="MNYFNVGKIVNTQGLQGEMRVLSVTDFAEERFKKGAELALFDEK
                     DQFVQTVTIASHRKQKNFDIIKFKDMYHINTIEKYKGYSLKVAEEDLNDLDDGEFYYH
                     EIIGLEVYEGDSLVGTIKEILQPGANDVWVVKRKGKRDLLLPYIPPVVLNVDIPNKRV
                     DVEILEGLDDED"
     gene            121454..122173
                     /gene="trmD"
                     /locus_tag="ACL3EZ_000122"
     CDS             121454..122173
                     /gene="trmD"
                     /locus_tag="ACL3EZ_000122"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052906 - tRNA
                     (guanine(37)-N1)-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HGR0391770.1"
                     /translation="MKIDILTLFPEMFSPLEHSIVGKAREKGLLDIQYHNFRENAEKA
                     RHVDDEPYGGSQGMLLRAQPIFDSFDAIEKKNPRVILLDPAGKQFDQAYAEDLAQEEE
                     LIFICGHYEGYDERIKILVTDEISLGDYVLTGGELAAMTMIDATVRLIPEVIGKESSH
                     QDDSFSSGLLEYPQYTRPYDYRGMVVPDVLMSGHHEKIRQWRLYESLKKTYERRPDLL
                     EHYQLTVEEEKMLAEIKENKE"
     gene            122185..122523
                     /locus_tag="ACL3EZ_000123"
     CDS             122185..122523
                     /locus_tag="ACL3EZ_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP cone domain-containing protein"
                     /protein_id="HGR0391771.1"
                     /translation="MQVIKRNGEIAEFNPDKIYQAILKAAQTVYVLTDDLRQNLAQVT
                     KKVVLDLQEAKVERATISMIQSMVEHRLLGAGYITIAEHYISYRLQRDLERSGYGDHI
                     AVHLHFEQIR"
     gene            complement(122554..122874)
                     /locus_tag="ACL3EZ_000124"
     CDS             complement(122554..122874)
                     /locus_tag="ACL3EZ_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001216095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0391772.1"
                     /translation="MRHKFQQVLDKIHDFLNGHDQPDQTETNSLTATIEEAIQKQTAV
                     HLILSETSFTGDIIKYDQQGQQIIVKNFAKNVSRIIRISDIQRLRFVPSTVQTAQKNR
                     FKKE"
     gene            122972..123187
                     /locus_tag="ACL3EZ_000125"
     CDS             122972..123187
                     /locus_tag="ACL3EZ_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000807422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HGR0391773.1"
                     /translation="MAEFTFEIEEHLLTLSENEKGWTKEINRVSFNGAPAKFDIRAWS
                     PDHTKMGKGITLSNEEFQTMVDAFKGN"
     gene            complement(123184..123372)
                     /locus_tag="ACL3EZ_000126"
     CDS             complement(123184..123372)
                     /locus_tag="ACL3EZ_000126"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0391774.1"
                     /translation="MTQYPFFYFENLYSMKIKEQTRKLAAGCSKHCFEVVDETDEVSN
                     HTYGKAKLMRFEEIFEEY"
     gene            complement(123392..123928)
                     /locus_tag="ACL3EZ_000127"
     CDS             complement(123392..123928)
                     /locus_tag="ACL3EZ_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000709035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HGR0391775.1"
                     /translation="MKKAHVYAIPAIGAALIAVLAQISLPIGPVPFTLQNFAIGLIAT
                     VFRPREAVLSAGLYLLLGAIGLPVFAGGGAGFQALVGPTAGYLWFYLVYSGLTSSLTN
                     SKSGVVKIFLANLLGDALVFVGGILSLHFLAGMAFEKALVVGVLPFIIPDLGKLLAIS
                     FISRPLLQRLKNQAYFTN"
     gene            124354..124692
                     /locus_tag="ACL3EZ_000128"
     CDS             124354..124692
                     /locus_tag="ACL3EZ_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0391776.1"
                     /translation="MKKRINKKASVFLVASVFSFSFATTASVVNAVTAHPAPSPIIDV
                     WEYGVNDNYGYSNYFVSSPSNIGSKSSVTNFWGTVKAQDKKDYGWAYSSATKSWNDVR
                     LNAYWDYYRF"
     gene            124758..126740
                     /locus_tag="ACL3EZ_000129"
     CDS             124758..126740
                     /locus_tag="ACL3EZ_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0391777.1"
                     /translation="MKLKLCIIGFFFCLIATIGLVTISDTEIPIPLPIDGAFSIQGKS
                     NLSNNEIYEMVRDLSKTEKVTIYKPIVQSSGQLKYVNFDDVNNEQLKSAPIVGMYYTL
                     GKMDVDSLKPLTMTGLQTVYMAYPWYIGGILQFTGTLRILLMGSIYLTLLVVLFVVRT
                     RQIKEGVIRRSLGLPIYDLRREYGISLIFELIMMALLMISYSSFLGNGFFTYSSKLFF
                     SLLLTNFILFQIIDLITFVLFWLTIQIEKPIEIIKNKAKNKLIFVVWLAIISIIILVS
                     GVFLQETKSSQSSINIQIQNLVPWDTVKDWRRIEFLGIESNSTKNREVNDSDGQYLQI
                     VAALKNLDFLYIERSSAYVPDFMKTSHVIENFSKQLENDGITNPEINKELIYINQTGA
                     NLQNKVNGTNYHLLDNKIATIYIPEKWKENQKSIENTVVAEQFIGTNYTREQLAVQII
                     PDGEKIFYFNEDADNNLKMKDILPLANVADSKDNIVVVLDTDKMMENNKFSLASNILY
                     KSLFSPEAVKKINEMTVLLNFSMNPVDVYQIVKLKIQSLEHQILLSQILQKIIYSIVF
                     ILIYQYVQLFITLKQNEYVKKIILGLSKTYIAISSLKYFMMTITMVILFTFLMTGQIE
                     LLYIGAASLLVLMLSIIMSFRKLSESYTKILKGDES"
     gene            126737..127360
                     /locus_tag="ACL3EZ_000130"
     CDS             126737..127360
                     /locus_tag="ACL3EZ_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGR0391778.1"
                     /translation="MTIDLLNVSKSFGSKKIFTDLNLIFESGKSYALIGGSGSGKSTL
                     LNIIGRLEKIDSGNVLVDKQDIWKIKERTFFKNTVGYVFQNYSLIDNKTVYDNLSLIT
                     KDKKTITDVLEKVGLSSDYLHQKIYELSGGQAQRVAIARMLMKPRKIILADEPTGALD
                     GEIGKEIIRLLLNETAEDKYVIIATHDPAVYNEVDVIIDMKDIGYKV"
     gene            127357..127857
                     /locus_tag="ACL3EZ_000131"
     CDS             127357..127857
                     /locus_tag="ACL3EZ_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0391779.1"
                     /translation="MKKKIYIALIFVTGVLAIFFFGKQMITKENINKPTVELTIYTLS
                     SSDTEKWNKVRQVETEEAIYFITVKEVSSSEEVFSNIIANGAATGFGVREEEVKKFNN
                     GLGDTIEDSKHNKLIEIEFFTFSDDGAGFVVANFDYGKEELNSQKKDIKELYKKIYES
                     FKEKNK"
     gene            complement(128023..129369)
                     /gene="gor"
                     /locus_tag="ACL3EZ_000132"
     CDS             complement(128023..129369)
                     /gene="gor"
                     /locus_tag="ACL3EZ_000132"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004362 - glutathione-disulfide reductase
                     (NADPH) activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006749 - glutathione metabolic process
                     [Evidence IEA];
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HGR0391780.1"
                     /translation="MREYDIIAIGGGSGGIATMNRAGEHGAKAAVIEEKKLGGTCVNV
                     GCVPKKIMWYGAQIAETFHQFGEDYGFKTTDLNFDFATLRRNREAYIDRARSSYDGSF
                     KRNGVDLIEGHAEFVDSHTVSVNGELIRAKHIVIATGAHPSIPNIPGAELGGSSDDVF
                     AWEELPESIAILGAGYIAVELAGVLHTFGVKTDLFVRRDRPLRGFDSYIVEGLVKEME
                     RTNLPLHTHKVPVKLEKTTDGITIHFEDGTSHTASQVIWATGRRPNVKGLQLEKAGVT
                     LNERGFIQVDEYQNTVVEGIYALGDVTGEKELTPVAIKAGRTLSERLFNGKTTAKMDY
                     STIPTVVFSHPAIGTVGLTEEQAIKEYGQDQIKVYKSSFASMYSACTRNRQESRFKLI
                     TAGSEEKVVGLHGIGYGVDEMIQGFAVAIKMGATKADFDATVAIHPTASEEFVTMR"
     gene            129634..130833
                     /locus_tag="ACL3EZ_000133"
     CDS             129634..130833
                     /locus_tag="ACL3EZ_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_function: GO:0042802 - identical protein binding
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HGR0391781.1"
                     /translation="MKKKNGKAKKWQLYAAIGAASVVVLGAGGILLFRQPSQTALKDE
                     PTHLVVAKEGSVASSVLLSGTVTAKNEQYVYFDASKGDLDEILVSVGDKVSEGQALVK
                     YSSSEAQAAYDSASRAVAKADRHINELNQARNEAASAPAPQLPAPVGGEDATVQSPTP
                     VAGNSVASIDAQLGDARDARADAAAQLSKAQSQLDATTVLSTLEGTVVEVNSNVSKSP
                     TGASQVMVHIVSNENLQVKGELSEYNLANLSVGQEVSFTSKVYPDKKWTGKLSYISDY
                     PKNNGEAASPAAGNNTGSKYPYTIDVTGEVGDLKQGFSVNIEVKSKTKAILVPVSSLV
                     MDDSKNYVWIVDEQQKAKKVEVSLGNADAENQEITSGLTNGAKVISNPTSSLEEGKEV
                     KADEATN"
     gene            130817..131518
                     /locus_tag="ACL3EZ_000134"
     CDS             130817..131518
                     /locus_tag="ACL3EZ_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0391782.1"
                     /translation="MKQLISLKNIFRSYRNGDQELQVLKNINLEVNEGEFVAIMGPSG
                     SGKSTLMNTIGMLDTPTSGEYYLEGQEVAGLGEKQLAKVRNQQIGFVFQQFFLLSKLN
                     ALQNVELPLIYAGVSSSKRRKLAEEYLDKVELTERSHHLPSELSGGQKQRVAIARALV
                     NNPSIILADEPTGALDTKTGNQIMQLLVDLNKEGKTIIMVTHEPEIAAYAKRQIVIRD
                     GVISSDSAQLGKEEN"
     gene            131520..132779
                     /locus_tag="ACL3EZ_000135"
     CDS             131520..132779
                     /locus_tag="ACL3EZ_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0391783.1"
                     /translation="MQNLKFAFSSIMAHKMRSLLTMIGIIIGVSSVVVIMALGDSLSR
                     QVNKDMTKSQKNISVFFSPKKSKDGSFTQKQSSFTVSGKEEEIPVEPPKPQESWVQEA
                     AKLKGVDSYYVTNSTNAILTYQDKKVENANLTGGNRTYMDAVKNEIIAGRSLREQDFK
                     EFASVILLDEELSISLFESPQEAINKVVEVNGFSYRVIGVYTSPEAKRSKIYGFGGLP
                     ITTNISLAANFNIDEIASIVFRVNDTSLTPTLGPELARKMTELAGLQQGEYQVADESV
                     VFAEIQQSFSFMTTIISSIAGISLFVGGTGVMNIMLVSVTERTREIGLRKALGATRAN
                     ILIQFLIESMILTLLGGLIGLTIASGLTALAGLLLQGLIEGIEVGVSIPVALFSLAVS
                     ASVGMIFGVLPANKASKLDPIEALRYE"
     gene            132903..134900
                     /gene="metG"
                     /locus_tag="ACL3EZ_000136"
     CDS             132903..134900
                     /gene="metG"
                     /locus_tag="ACL3EZ_000136"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0004825 - methionine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006431 - methionyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HGR0391784.1"
                     /translation="MSEKNFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRLMGYDV
                     FYLTGLDEHGQKIQQKAEEAGITPQAYVDGMAVGVKELWQLLDISYDKFIRTTDDYHE
                     KVVAQVFERLLAQDDIYLGEYSGWYSVSDEEFFTESQLAEVFRDEAGNVTGGIAPSGH
                     EVEWVSEESYFLRLSKYQDRLVEFFKAHPEFITPDGRLNEMLRNFIEPGLEDLAVSRT
                     TFTWGVPVPSNPKHVVYVWIDALLNYATALGYAQDEHGNFDKFWNGTVFHMVGKDILR
                     FHSIYWPILLMMLDVKLPDRLIAHGWFVMKDGKMSKSKGNVVYPEMLVERYGLDPLRY
                     YLMRNLPVGSDGTFTPEDYVGRINYELANDLGNLLNRTVSMINKYFDGQIPAYVEGVT
                     EFDHVLAEVAEQSIADFHTHMEAVDYPRALEAVWTLISRTNKYIDETAPWVLAKDEAL
                     RDQLASVMSHLAASIRVVAHLIEPFMMETSRAVLTQLGLEEVSSLENLSLADFPADVT
                     VVAKGTPIFPRLNMEEEIAYIKEQMEGNKPAVEKEWNPDEVELKLNKDEIKFEDFDKV
                     EIRVAEVKEVSKVEGSDKLLQFRLDAGDGEDRQILSGIAKYYPNEQELVGKKVQIIAN
                     LKPRKMMKKYVSQGMILSAEHDGKLTLLTVDPAVPNGSVIG"
     gene            134950..135183
                     /locus_tag="ACL3EZ_000137"
     CDS             134950..135183
                     /locus_tag="ACL3EZ_000137"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0391785.1"
                     /translation="MKIKEQTRKLAAGCSKHSFEVVDETDEVSSKHSFEVVDETDEVS
                     SKHCFEVVDETDEVSSKHSFEVVDETDEVSNHT"
     gene            135321..135641
                     /locus_tag="ACL3EZ_000138"
     CDS             135321..135641
                     /locus_tag="ACL3EZ_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HGR0391786.1"
                     /translation="MKETQLLKGVLEGCVLDMIGQKERYGYELVQTLREAGFDTIVPG
                     TIYPLLQKLEKNQWIRGDMRPSPDGPDRKYFSLMKEGEERVSVFWQQWDDLSQKVEGI
                     KNGG"
     gene            135645..136460
                     /locus_tag="ACL3EZ_000139"
     CDS             135645..136460
                     /locus_tag="ACL3EZ_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0391787.1"
                     /translation="MKKMKYYEETSALLHEFSEENQKYFEELWESFNLAGFLYDEDYL
                     REQIYLMMLDFSEAERDGMSAEDYLGKNPKKIMKEILKGAPRSSIKESLLTPILVLAV
                     LRYYQLLSDFSKGPLLTVNLLTFLGQLLIFLIGFGLVATILRRSLVQDSPKMKIGTYI
                     VVGTIVLLVVLGYVGMASFIQEGAFYIPAPWDSLSVFTISLVIGIWNWKEAVFRPFVS
                     MIIAHLVVGSLLRYYEWMGISNVFLTKVIPLAVLFIGIFVLFRGFKKIKWSEV"
     gene            136535..137461
                     /locus_tag="ACL3EZ_000140"
     CDS             136535..137461
                     /locus_tag="ACL3EZ_000140"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HGR0391788.1"
                     /translation="MRYITLGQDDKELSEIVLGMMRIKDKSVKEVEELVETALSVGIN
                     AFDLADIYGRGRCEELLGLVLKNRPDLREKMWIQSKCGIRIEEFTYFDFSKDYIIKSV
                     DGILQRLKIDHLDSLLLHRPDALMESDQVAEAFDLLYKQGKVRDFGVSNQNPMMMELL
                     KKDVKQPLAVNQLQLSAAFTPGFESAFHVNMEDSQAAMRDGSIFEYCQLHDVVIQAWS
                     VLQFGYFKGNFVGNEKFQALNQVLDRLAIKYGVTSSTIAISWILRYPAKMQAVVGTTN
                     PKHLREVSRAANFSLTRKEWYEIYLAAGNNLP"
     gene            137557..137793
                     /locus_tag="ACL3EZ_000141"
     CDS             137557..137793
                     /locus_tag="ACL3EZ_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018367459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HGR0391789.1"
                     /translation="MTFEEILPGLKAKRKYVRTGWGGAENYVQLFDTIEQNGLALEMT
                     PYFLINVSGEGEGFSMWSPTVCDVLATDWVEVHD"
     gene            137786..138484
                     /locus_tag="ACL3EZ_000142"
     CDS             137786..138484
                     /locus_tag="ACL3EZ_000142"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HGR0391790.1"
                     /translation="MTKRVLITGVSSGIGLAQARLFLEKGYQVYGVDQGEKPLLEGDF
                     HFLQRDLTLDLEPIFDWCPQVDVLCNTAGVLDAYKPLLEQTAQDIQEIFEINYIIPVE
                     LTRYYLTQMLENKKGIIINMCSIASSLAGGGGHAYTSSKHALAGFTKQLALDYAEARI
                     QVFGIAPGAVKTAMTAADFETGGLADWVASETPIKRWIEPEEVAEVSLFLASGKASAM
                     QGQILTIDGGWSLK"
     gene            138495..138974
                     /locus_tag="ACL3EZ_000143"
     CDS             138495..138974
                     /locus_tag="ACL3EZ_000143"
                     /EC_number="3.6.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HGR0391791.1"
                     /translation="MEIKNHFGVYCVCFENGKLLCIEKTRGPYQHRYDLPGGSQQLGE
                     GLTETLTREVMEETGFTVRSYSNPRIYDVFVREELKNFMVHHVIALYDVEMNESAPQV
                     TISEAVSDGANDSLGYIWMDIQEITEENASPLVLKVKSELLGLPELDKTSYMNWKVK"
     gene            138982..139710
                     /locus_tag="ACL3EZ_000144"
     CDS             138982..139710
                     /locus_tag="ACL3EZ_000144"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR0391792.1"
                     /translation="MELFKTWKKNMVLYGLKSQIGTVYRNNDRTTSFYDVGNFLYLAG
                     ELDSRFWEDFVRKYGLDYKIIISENTNWQDFLHRKVGLNSFTRYSFKDKANFQVEFLN
                     NLVTHLEEGYNIVPIDNHIYNCFSTEEWSQDLQGDFESYQDFVLKGGFGFVILKNNEL
                     IAGISSGLVYRKAVEVEVATRPNEQGNGFAKKLGAAMILESLNRDMFPLWDAHNEASK
                     KVAEFLGYELSEPYEAFELEEILI"
     gene            139752..140621
                     /locus_tag="ACL3EZ_000145"
     CDS             139752..140621
                     /locus_tag="ACL3EZ_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016772 - transferase activity,
                     transferring phosphorus-containing groups [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative PEP-binding protein"
                     /protein_id="HGR0391793.1"
                     /translation="MRNQLALSGEKILEKIYPQLFHHVGMIRGEYLLRELNQNIILAS
                     CQQFVKDYLETICSLYSDEEVWYRFSELTNTEANCLVGTREFFDEGHPLFGYRGTRRL
                     LACLDEFQAEAHVVTEVYQTNPNLSVIFPFVNDADQLKQAITVLRQQGFTGKVGTMIE
                     LPSAYFDLSSILETGISKIVVGMNDLTSFVFATMRNSQWHDMESPIMLDMLRDMQDKA
                     RKNKIDFAVAGYLNTSFIQKMNQLGIKCIIHYSSIPEIFDLEIDHPDHLKHIKEESKK
                     LQRSTHDTARNVE"
     gene            140596..141036
                     /locus_tag="ACL3EZ_000146"
     CDS             140596..141036
                     /locus_tag="ACL3EZ_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HGR0391794.1"
                     /translation="MIPQEMWNKYKQINPLIGDEIDAWAFGVEPDLLADLVFKGEKTA
                     TASAYDLYVLEDEPLPQVGTFDIILDSQNQSVCIVEITKVSVELFNQVSAQHAFKEGE
                     GDKSLAYWRQVHEDFFTDCLGEVGLTFTPESKVVLEEFRKVYPL"
     gene            141159..143705
                     /locus_tag="ACL3EZ_000147"
     CDS             141159..143705
                     /locus_tag="ACL3EZ_000147"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001149089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004177 - aminopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008237 - metallopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HGR0391795.1"
                     /translation="MQAVEHFIKQFVPEHYDLFLDLSRETKTFSGKVTITGQAQSDRI
                     SLHQKDLEITSVEVAGQARPFTVDHDNEALHIELAEAGQVELVLAFSGKITDNMTGIY
                     PSYYTVDGVKKEVLSTQFESHFAREAFPCVDEPEAKATFDLSLRFDQAEGELALSNMP
                     EIDVENRKETGIWKFETTPRMSSYLLAFVAGDLQGVTAKTKNGTLVGVYSTKAHPLSN
                     LDFSLDIAVRSIEFYEDYYGVKYPIPQSLHIALPDFSAGAMENWGLVTYREVYLVVDE
                     NSTFASRQQVALVVAHELAHQWFGNLVTMKWWDDLWLNESFANMMEYVCVDTIEPSWN
                     IFEDFQTGGVPLALERDATDGVQSVHVEVKHPDEINTLFDGAIVYAKGSRLMHMLRRW
                     LGDADFAKGLHAYFEKHQYSNTIGSDLWDALGQASGRDVAAFMDSWLEQPGYPVLTVK
                     VENDVLKISQKQFFIGENEDKNRLWVVPLNSNWKGLPDTLETESIEIPGYAALLAENE
                     GALRLNTENTAHYITDYQGDLLEAVLAELETLDNTSKLQIVQERRLLAEAGHISYADL
                     LPVLDKLAKEESYLVVSAVSQVISALERFIDEGTDAETAFKGLVAKLARHNYDRLGFE
                     AKDGESDEDELVRQLAVSMMIRSNDAEARQVASQIFATHKENLAELPAAIRSQVLINE
                     MKHHETKDLLALYLDTYTHATDAVFKRQLAAALAYSTDADNIQNLITSWKDKFVVKPQ
                     DLSAWYYQFLAHQATQKTAWSWARENWAWIKAALGGDMSFDSFVILPAHVFKTQQRLA
                     EYKEFFEPQLSDLALSRNIGMGIKEIAARVDLISREKAAVEAVVLQYGNA"
BASE COUNT        44202 a        25649 c        31105 g        42848 t
ORIGIN      
        1 tccagtattt gacaatattg aagcagctat taaagaacat ggattaagct aattctaatt
       61 tgttaacatt catataacat aaaaaaggga ggaactgtta tggatgcaat ctttgaccta
      121 atcggaaagg ttttcaatcc catcttagaa atgggtggac ctgtcatcat gttgatcatt
      181 ttgacagtat tggctttact ttttggagtg aaattctcca aagcgcttga aggtggtatc
      241 aaacttgcca tcgctcttac aggtatcggt gctatcatcg gtatgctaaa tggtgctttc
      301 tcagcatcac ttgcaaaatt cgttgaaaac actggtatcc aattgagtat tacagacgtt
      361 ggttgggcac cactcgcaac aatcacttgg ggttctgctt ggacactata cttcttgctc
      421 atcatgttga ttgtcaacgt agtgatgctt gctatgaaga aaaccgatac acttgatgtc
      481 gatatctttg atatctggca cttgtctatc acaggtctct tgattaaatg gtatgctgat
      541 aacaatggtg tgagtcaagg ggtttcactc tttattgcta cagcagctat cgtccttgtc
      601 ggtgtgttga aaattatcaa ctctgacttg atgaaaccta catttgatga ccttcttaac
      661 gccccaagtt catcaccaat gacatcaact cacatgaact acatgatgaa cccagttatc
      721 atggttttgg ataagatttt tgaaaaattc ttcccaggcc ttgataaata tgactttgat
      781 gctgctaaat tgaacaagaa aatcggtttc tggggatcta aattcttcat cggtttcatc
      841 cttggtatcg ttatcggtat tatgggaact ccacatccaa ttgcaggtgt tgcagatgca
      901 gataaatggc gtcttgttat caaaggatgg ttgtctcttg gtttgactgc cggtgtatct
      961 ttggaactct tctcacttat cggttcatgg ttcatcgcag ccgtagaacc actatcacaa
     1021 ggtattacaa acgttgctac taaacgtctt cgaggacgta aattcaatat cggtcttgac
     1081 tggccattca tcgctggtcg tgctgaaatc tgggcttgtg ccaacgtact tgcaccaatc
     1141 atgttgattg aagcagtgct tctttcaaaa gttggaaatg gtatcttgcc acttgcaggt
     1201 atcatcgcta tgggtgttac tccagctctc ttggttgtaa ctcgtggtaa attgctccgt
     1261 atgattatct tcggaacact cttgttgcca ctcttccttc tttcaggtac acttattgca
     1321 ccatttgcaa cagaacttgc taaaggtgta ggtgccttcc cagaaggtgt gagccaaact
     1381 caattgatta ctcactctac tcttgaagga ccaatcgaaa aacttcttgg ttggacaatt
     1441 ggtaacacta caactggtga tatcaaagca atccttggtg cagtagtctt ccttgtattc
     1501 tatatcggta tctttgcttg gtacagaaaa caaatgatca aacgtaacga agagtacgca
     1561 gcaaaagcaa aataatgcgc tcctataaaa tataaactca atgaaaatca aagagcaaac
     1621 taggaaacta gccgcaggtt gctaaaaaca cagttttgag gttgtagata agactgacga
     1681 agtcagctca aaacatggtt ttgaggttgt agatgaaact gacgaagtca gtaatcatat
     1741 ctacggcaag gcgacgctga cgaagtttga attggatttt cgcagagtgt aaattgttga
     1801 aactaggttg tcataccatg tataccactt gggctttggt agtagctaac tgcactaaat
     1861 ataatataag gagggtttta tggggaaagg ccattggaat cggaaaagag tttatagcat
     1921 tcgtaagttt gctgtgggag cttgctcagt aatgattggg acttgtgcag ttctattagg
     1981 aggaaatata gctggagaat ctgtagttta tgcggatgaa acacttatta ctcatactgc
     2041 tgagaaacct aaagaggaaa aaatgatagt agaagaaaag gctgataaag ctttggaaac
     2101 taaaaatgta gttgaaagga cagaacaaag tgaacctagt tcaactgagg ctattgcatc
     2161 tgagaagaaa gaagatgaag ccgtaactcc aaaagaggaa aaagtgtctg ctaaaccgga
     2221 agaaaaagct ccaaggatag aatcacaagc ttcaagtcaa gaaaaaccgc tcaaggaaga
     2281 tgctaaagct gtaacaaatg aagaaatgaa tcaaatgatt gaagacagga aagtggattt
     2341 taatcaaaat tggcacttta aactcaatgc aaattctaag gaagccatta aacctgatgc
     2401 agacgtatct acgtggaaaa aattagattt accgtatgac tggagtatct ttaacaattt
     2461 cgatcatgaa tctcctgcac aaaatgaagg tggacaactc aacggtgggg aagcttggta
     2521 tcgcaagact ttcaaactag atgaaaaaga cctcaagaaa aatgttcgcc ttacttttga
     2581 tggcgtctac atggattctc aagtttatgt caatggtcag ttagtggggc attatccaaa
     2641 tggttataac cagttctcat atgatatcac caaatacctt cacaaagatg gtcgtgagaa
     2701 tgtgattgct gtccatgcag tcaacaaaca gccaagtagc cgttggtatt caggaagtgg
     2761 tatctatcgt gatgtgactt tacaagtgac agataaggtg catgttgaga aaaatgggac
     2821 aactatttta acaccaaaac ttgaagaaca acaacatggc aaggttgaaa ctcatgtgac
     2881 cagcaaaatc gtcaatacgg acgacaaaga ccatgaactt gtagccgaat atcaaatcgt
     2941 tgaacgaggt ggtcgtgctg taacaggctt agttcgtaca gcgagtcgta ccttaaaagc
     3001 acatgaatca acaagcctag atgcgatttt agaagttgaa agaccaaaac tctggaccgt
     3061 tttaaatgac aaacctgcct tgtacgaatt gattacgcgt gtttaccgtg acggtcaatt
     3121 ggttgatgct aagaaggatt tgtttggtta ccgttactat cactggactc caaatgaagg
     3181 tttctctttg aatggtgaac gtattaaatt ccatggagta tccttgcacc acgaccatgg
     3241 ggcgcttgga gcagaagaaa actataaagc agaatatcgc cgtctcaaac aaatgaagga
     3301 gatgggagtt aactctatcc gtacaaccca caaccctgct agtgagcaaa ccttgcaaat
     3361 cgcagcagaa ctaggtttac tcgttcagga agaggccttt gatacgtggt atggtggcaa
     3421 gaaaccttat gactatggac gtttctttga aaaagatgcc actcacccag aagctcgaaa
     3481 aggtgaaaaa tggtctgatt ttgacctacg taccatggtc gaaagaggca aaaacaaccc
     3541 tgctatcttc atgtggtcaa ttggtaatga aataggtgaa gctaatggtg atgcccactc
     3601 tttagcaact gttaaacgtt tggtcaaggt tatcaaggat gttgataaga ctcgctatgt
     3661 taccatggga gcagataaat tccgtttcgg caatggtagc ggagggcatg agaaaattgc
     3721 tgatgaactc gatgctgttg gatttaacta ttctgaagat aattacaaag cccttagagc
     3781 taagcatcca aaatggttga tttacggttc agaaacatca tcagcaaccc gtacacgagg
     3841 aagttactat cgccctgaac gtgaattgaa acatagcaat ggacctgagc gtaattatga
     3901 acagtcagat tatggaaatg atcgtgtggg ttgggggaaa acagcaaccg cttcatggac
     3961 ttttgaccgt gacaacgctg gctatgctgg acagtttatc tggacaggta cggactatat
     4021 tggtgaacct acaccatggc acaaccaaaa tcaaactcct gttaagagct cttactttgg
     4081 tatcgtagat acagccggca ttccaaaaca tgacttctat ctctaccaaa gccaatgggt
     4141 ttctgttaag aagaaaccga tggtacacct tcttcctcac tggaactggg aaaacaaaga
     4201 attagcatcc aaagtagctg actcagaagg taagattcca gttcgtgctt attcgaatgc
     4261 ttctagtgta gaattgttct tgaatggaaa atctcttggt cttaagactt tcaataaaaa
     4321 acaaaccagc gatgggcgga cttaccaaga aggtgcaaat gctaatgaac tttatcttga
     4381 atggaaagtt gcctatcaac caggtacctt ggaagcaatt gctcgtgatg aatctggcaa
     4441 ggaaattgct cgagataaga ttacgactgc tggtaagcca gcggcagttc gtcttattaa
     4501 ggaagaccat gcgattgcag cagatggaaa agacttgact tacatctact atgaaattgt
     4561 tgacagccag gggaatgtgg ttccaactgc taataatctg gttcgcttcc aattgcatgg
     4621 ccaaggtcaa ctggtcggtg tagataacgg agaacaagcc agccgtgaac gctataaggc
     4681 gcaagcagat ggttcttgga ttcgtaaagc atttaatggt aaaggtgttg ccattgtcaa
     4741 atcaactgaa caagcaggga aattcaccct tactgctcac tctgatctct tgaaatctag
     4801 tcaagtcact gtctttactg gtaagaaaga aggacaagaa aagactgttt tggggacaga
     4861 ggtgccaaaa gtacagacca ttattggaga ggcacctgaa atgcctacca ctgttccgtt
     4921 tctatacagt gatggtagtc gtgcagaacg tcctgtaacc tggtcttcag tagatgtgag
     4981 caagcctggt attgtaacgg tgaaaggtat ggctgacgga cgagaagtag aagctcgtgt
     5041 agaagtgatt gctcttaaat cagagctacc agttgtgaaa cgtattgctc caaatactga
     5101 cttgaattct gtagacaaat ctgtttccta tgttttgact gatggaagtg tacaagagta
     5161 cgaagtagat agctgggaga ttacggaagt agataaagcc aaactttcag tagctggatc
     5221 acgtattcaa atgactggtc agttagctgg agaaactatt catgcaaccc ttgtggtaga
     5281 agaaggaaat gctgcagcac ctgtagtgcc aactgttact gttggaggtg aagcagtaac
     5341 aggtcttact agtcgacaac caatgcaata tcgtactcta tcttatggtg cccaattgcc
     5401 agaagtcaca gcaagtgctg aaaatgctga tgtgacagtt cttcaagcaa gcgcagcaaa
     5461 cggcatgcgt gcaagcatat ttgttcagcc taaagatggt ggccctcttc aaacctatgc
     5521 aattcaattc ctagaagaag caccaaaaat tgctcacttg agcttgcaag tggaaaaagc
     5581 tgacagtctc aaagaagacc aaactgtcaa attgtcggtt cgagctcact atcaagatgg
     5641 aacgcaagct gtattaccag ctgataaagt aaccttctct acaagtggtg aaggggaagt
     5701 cgcaattcgt aaaggaatgc ttgagttgca taagccagga gcagtcactc tcaaagcgga
     5761 atatgaggga gctaaaggcc aagttgaact cactatccaa gccaatactg agaagaagat
     5821 tgcgcaatct atccgtcctg taaatgtagt cacagatttg catcaaaaac ctactcttcc
     5881 aacaacagta acggttgagt atgacaaagg tttccctaaa gctcacaaag tcacttggca
     5941 agctattccg aaagaaaaac tagactccta tcaaacattt gaagtactag gtaaagttga
     6001 aggaattgac cttgaagcgc gtgcaaaagt ctctgtagaa ggtatcgttt cagttgaaga
     6061 agtcagtgtg acaactccaa tcgcagaagc accacaatta ccagaaagtg ttcggacata
     6121 tgattcaaat ggtcacgttt catcagctaa ggttgcatgg gatgcgattc gtccagagca
     6181 atacgctaag gaaggtgtct ttacagttaa tggtcgctta gaaggtactc aattaacaac
     6241 taaacttcat gttcgcgtat ctgctcaaac tgagcaaggt gcaaacattt ctgaccaatg
     6301 gaccggttca gaattgccac ttgcctttgc ttcagactca aatccaagcg acccagtttc
     6361 aaatgttaat gacaagctca tttcctacaa taaccaacca gccaatcgtt ggacaaactg
     6421 gaatcgtact aatccagaag cttcagtcgg tgtcctattc ggagattcag gtattttgag
     6481 caaacgttca gttgataact taagcgttgg cttccatgaa gaccatggag ttggtgcacc
     6541 gaagtcttat gtgattgagt attatgttgg taagactgtc ccaacagctc ctaaaaaccc
     6601 tagttttgtt ggtaatgagg accatgtctt taatgattct gccaactgga aaccagttac
     6661 taatctaaaa gcccctgctc aactcaaggc tggagaaatg aaccacttta gctttgataa
     6721 agttgaaacc tatgctgttc gtattcgcat ggtgagagca gacaacaaac taggaacgtc
     6781 tatcacagag gtacaaatct ttgcgaaaca agttgcggca gccaagcaag gacaaacaag
     6841 aatccaagtt gacggtaaag acttagcaaa cttcaaccct gatttgacag actactacct
     6901 tgagtctgta gatggaaaag ttacggcagt cacagcaagt gttagcaaca atggcctcgc
     6961 taccgtcgtt ccaagcgttc gtgaaggtga gccggttcgt gtcatcgcga aagctgaaaa
     7021 tggcgacatc ttaggagaat accgtctgca cttcactaag gataagaact tactttctca
     7081 taaaccagtt gctgcggtta aacaagctcg cttgctacaa gtaggtcaag cacttgaatt
     7141 gccgactaag gttccagttt acttcacagg taaagacggc tacgaaacaa aaaacctgac
     7201 agttgaatgg gaagaagttc cagcggaaaa tctgataaaa gcaggtcaat ttaccgttcg
     7261 aggccatgtc cttggtagtg atcttgttgc tgaggtcact gtacgagtga cagacaaact
     7321 aggcgaagct ctttcagata accctaacta tgatgaaaac agtaaccagg cctttgcttc
     7381 agcaaccaat gatattgaca aaaactctca tgaccgcgtt gactatctca atgacggaga
     7441 tcattcagaa aatcgtcgtt ggacaaactg gtctccaaca ccatcttcta atccagaagt
     7501 atcagcgggt gtgatcttcc gtgaaaatgg taagattgta gaacggactg ttgctcaagc
     7561 caaacttcac ttctttgcag atagtggtac ggatgcacca actaaactcg ttttagaacg
     7621 ctatgtcggt ccagagtttg aagtgccaac ctactattca aactaccaag cctacgacgc
     7681 agaccatcca ttcaacaatc cagaaaattg ggaagctgtg ccttatcgtg cggataaaga
     7741 catcgcagct ggtgatgaaa tcaacgtaac atttaaagct gtcaaagcca aagctatgag
     7801 atggcgtatg gagcgtaaag cagataagag cggtgttgcg atgattgaga tgaccttcct
     7861 tgcaccaagt gaattgcctc aagaaagcac gcaatcgaag attcttgtag atggaaaaga
     7921 acttgctgat ttcgctgaaa atcgtcaaga ctatcaaatt acctataaag gtcaacggcc
     7981 aaaagtctca gttgaagaaa acaatcaagt agcttcaact gtggtagata gtggagaaga
     8041 tagccttcca gtacttgttc gcctcgtttc agaaagtgga aaacaagtca aggaataccg
     8101 tatccagttg actaaggaaa aaccagtttc tgagaagaca gttgctgctg tacaagaaga
     8161 tcttccaaaa ctcgaatttg ttgaaaaaga tttggcctac aagacagttg agaaaaaaga
     8221 ttcaacactg tatctaggtg aaactcgtgt agaacaagaa ggaaaaactg gtaaagaacg
     8281 tatctttaca gcgattaatc ctgatggaag taaggaagaa aaactccgtg aagtggtaga
     8341 agctccgaca gaccgcatcg tcttggttgg aaccaaacca gtagctcaag aagctaaaaa
     8401 accacaagtg tcagaaaaag cagatacaaa accaattgat tcaagtgaag ctagtcaaac
     8461 taataaagcc cagttaccaa atacaggtag tgcggcaagc caagcagcag tagcagcagg
     8521 tttagctctt ctaggtttga gtgcaggatt agtagttact aaaggtaaaa aagaagacta
     8581 gaaattttga taccttcttt atcattaaag accaaagaaa aactcttgtc ctaaatagaa
     8641 gataaagagt ctggaacaaa atagttctca accacaaaaa agctagatat ttccaattgc
     8701 ggaactctag ctttttaatt ttgagtcgtt ctcttattgt atagtagatt gaaactagag
     8761 tagtacactt ctacttctaa aacattgtta gaaatcgatt tgactgtcct tatcgatttg
     8821 tcctgttctt atttcatttc actatgtttt aggaggttat tggccataag taccaatccc
     8881 atgtcaattc tcacttgacg cttgcctctc agattacatc tcttgtaacc caaacaagcc
     8941 tttatctgcc caaagacagg ttctacatca atcttgcgtt gagcgaaaat ctgtctatct
     9001 tggggagata aaagcgcctg acattcttta gctttcaagt tttgatagcg ttcgttcata
     9061 tacaatccct tttgaggggc tgattcaggt tcatcagcgt agtaaacctt gatttcctgt
     9121 tgaaagtctg tctgtgtttt ctggtacttg atatggtgaa aacgatagca ccagccatca
     9181 ggatgtatgt agctatcctc cttgtcatta tagtgccaat tcgctaagtt tttagctgac
     9241 tgtttatacc ctctcttttg ttccttatca aacatggcat atttaatcag aaggggagtg
     9301 atttcttctt gaaaatagac ttgtatctgt tcttgaagtt tggcggagaa tttctctgtc
     9361 gttttcttcc acacaaaact atacttgttg gcattggatt caatcttagt tccgtcaata
     9421 aacaaacaat ctaaggtcac taactcttcc atttttcaat ttttcgacca gagaaaatcc
     9481 cttgtgaata ggcaaataga agagtagata caagcatttt agggtgataa gacgggcgac
     9541 caaaggcatg ataggaggtg tagaagtgac gttcctccaa ggtattcacc actttttcaa
     9601 tagtaaagac gagatggtct tgtggtaaga aggaactgat ttctagtggt aaagttgttt
     9661 gatttgtgtt atagtgaata tgcatgggat agcctttcta aatggtttat taagcaattc
     9721 tattttacca agactatcgt aaccatgcaa aaaagcaacg gcaaatccgt tgcctttttt
     9781 ggatataaga gactattgtc ccagactctt ttctttgtat aaaattgtat agtgttattg
     9841 tctatactat tttgtagaga aagcaaaaat ccctagaaaa tgcttaggga ttcgactatt
     9901 tcattaagaa caattcaaca atcatctcta tatacatgat aagggttaat aaaaatcctg
     9961 tacgccagaa gaatttgatg aatttaggat agtaaaagct gcgttttttt aaaaggaaga
    10021 aaaagacgag aataatggct aggaacgaga gggctagccc cagtctaggg aggaaattat
    10081 gggtaaaggt tttagctgta atcaagtaat actcaaatac caagactgga aaagccaaat
    10141 ccgcaaagtt tcgtcctagt ttttttaatc taaaaagttt ggttaggata atgcagacga
    10201 ctaaggtcag tatcaataat aaaatagatg ctaatttcat taaaatcata cccatattgt
    10261 atcataaaaa aaggctaatg gaaacgagaa acagaggaat ttataggaaa gtcaggcttt
    10321 tgagattgtg ggtgattttt gttataatga aagttataaa atcttatgat accttgaatg
    10381 attattatcg aaaactcttt ggagaaaaga cttttaaagt ccctattgat gcgggatttg
    10441 actgtcccaa tcgtgatgga actgtggctc atggaggctg tactttttgt acggtttccg
    10501 gttctggaga tgccattgta gccccagatc cgcctatccg tgagcaattt tataaggaaa
    10561 ttgactttat tcatcgtaag tggccagatg ttcagaagta tctggtttat tttcaaaatt
    10621 ttaccaacac ccatgaaaag gtggaagtta ttcgagagcg ttatgaacag gctatcaatg
    10681 agccaggtgt ggtaggaatc aatattggaa cgcgcccaga ctgtttacca gacgaaacca
    10741 tcgaatattt ggctgagtta tcggagtgca tgcatgtgac ggttgaattg ggcttgcaga
    10801 ctacttatga agcaacctct gacctgatta accgtgcgca ttcttatgaa ttgtaggtgg
    10861 aaacggtcaa gcgtttgaga aagtatccaa aaattgagat tgtttcccat ttgatcaatg
    10921 gtttgcctgg tgaaacccat gagatgatgg ttgaaaatgt ccgccgttgt gtcacggata
    10981 acgatattca agggattaaa ctgcatttgc tccatcttat gacaaatact cgtatgcaac
    11041 gagattacca tgagggacgt ttacaattga tgagtcagga cgaatatgtc agggtcatct
    11101 gtgaccaact ggaaattatt cccaaacata tcgtcatcca tcgaattaca ggagatgcgc
    11161 ctagggatat gctgattggt cctatgtgga gcctcaataa atgggaagtc ctcaacagca
    11221 ttgagatgga gatgagacgt cgtggaagtg ttcaaggatg caaggctgta aaacaggagt
    11281 ttgaaaatga aaagaccact tgagatggca catgattttt tggctgaggt cgtgacaaaa
    11341 gaggatgtcg tagtggatgc gactatggga aatggtcatg acacgctttt tttagccaag
    11401 ctagccaagc aagtctatgc ctttgatatt cagaagcaag ccttggaaaa gacccaagag
    11461 cgtttgcatc aggctggctt gacaaatgcc cagttaatct tgcaaggcca tgagacactg
    11521 gaccagtttg tgacaaaagc taaggcaggg atttttaatt tgggctattt gccgtcagct
    11581 gataagtctg tcatcacccg accgcagaca acgattgagg cattagaaaa gctatgtggc
    11641 ttacttgtca aaggtggacg aattgctatt atgatttact atggtcatga aggaggcgac
    11701 ctcgagagag atgctgtctt ggattttgtg atccagttga accaacaaga gtacacagct
    11761 gccatttacc gaactttaaa ccaagtcaac aacccgccgt ttttagtgat gattgaaaaa
    11821 ttagagagat acagacatgg ataaacaata cctacacgaa aagctggatg ccatgcgcca
    11881 gaattttgtt gaatcaacct accacgaacg agcggtgggc gtgctagacc aagcgcatat
    11941 gagcaaaaaa atgcttaaaa tcaagaaaaa attagttgct cttgaaatgg aacggtgcca
    12001 gagaaaaatt gagcacaaag actgttccaa gattgaccaa aaaatcaaag agcagaagga
    12061 gatatttgaa tcctgttgta aaaaagatta aggaggacgt gcgtggaatt actgatttac
    12121 ctcatcctat ttttactggt cttgattgtc tcaagtacaa ccaataagct cctacccttt
    12181 ttgcctctcc ctttggtgca gattcttttg ggaattgtga ttggtctctt tttacccaat
    12241 actgactttc accttaatac ggagttgttt ttggcactgg ttatcggccc cttgcttttc
    12301 cgagaggctg aagaagcaga tgttacggct attttaaaac actggcgaat cattgtttat
    12361 ctcatatttc cagtgatttt tatctcgacc ctgagtttgg gtggcttggc ccatcttctt
    12421 tggttcagcc ttcccttggc agcttgcttg gctgttgggg cagcccttgg tcctacggac
    12481 ttggtggcct ttgcctctct ttcggagcgt tttagctttc ctaagcgcgt gtccaatatt
    12541 cttaagggcg aaggactctt gaatgatgct tctggtttgg tggcttttca ggtagctttg
    12601 acagcttgga caactggagc tttttctctg gggcaagcta gcagttcact catcttttca
    12661 atcctaggcg gttttttaat tggattttta acagctatga ccaaccgctt cctccatacc
    12721 ttcttgctaa gtgtgcgcgc aacggatatt gccagtgaac ttttattaga gttgagtttg
    12781 cctctagtga ccttctttct ggcagaagaa gtccatgttt cagggattat tgccgtcgta
    12841 gttgctggaa ttttaaaggc aagtcgcttc aagaaaatca cgctcctcga agcccaagtg
    12901 gatacggtga ccgagacggt ctggcataca gtgaccttta tgctcaacgg ttctgtcttt
    12961 gtgattttag ggatggagtt ggaaatgata gcagaaccta tcttgaccaa tccaatctat
    13021 aatcctctac ttttattgct atctctcatc gcccttacct ttgtcctctt tgtcattcgt
    13081 tttattatga tctatggcta ttatgcctat agaacccgac gcctcaagaa aaagctaaat
    13141 aagtatatga aggacatgtt tctcttgacc ttttcaggtg ttaagggaac ggtgtcgatt
    13201 gctacgattc tcttgatacc aagtaatcta gaacaggagt atcctctctt gcttttcctt
    13261 gttgcaggtg tgacgcttgt cagcttttta acaggtctct tggtcttgcc tcatctttct
    13321 gatgaagagg aagaaagcaa ggattatctc atgcatatcg ccattttgaa tgaagtaacg
    13381 ctagagttgg aaaaagagtt ggaagacacc agaaataaac ttcccctcta tgcggctatt
    13441 gacaattatc atggacgtat tgaaaatctc attttaagcc aagaaaacca ggatgatcaa
    13501 gaagactggg ctgctttgaa actcttgatt cttagtattg aaagtgatgg tttggaacag
    13561 gcctatgaag aggggaacat tagcaatcgt gcttaccgag tttaccaacg ttatctgaaa
    13621 aatatagaac aaggaatcaa tcgtaaactt gcctcaagac tgacctatta ttttcttgtt
    13681 tccttgagga ttttacgttt tctccttcat gaagttttta ctcttggaaa gaccttccgt
    13741 agctggaagg acaaggagca aagccgtctc cgtgctcttg attatgacca aattgcagag
    13801 ctctatcttg ccaatacaga gatgattatt gaaagtttgg aaaacctgaa gggagtctac
    13861 agacgctctt tgattagttt tatgcaggag tctcgtcttc gagaaacagc tattatcagc
    13921 agtggtgcct ttgtcgaacg ggttatcaat cgtgtcaaac ccaacaatat cgatgaaatg
    13981 ctgagaggct attatctgga gcgcaagttg attttcgaat acgaagaaaa acgattgatt
    14041 acgactaagt atgccaagaa attacgacaa aatgtaaata acttagagaa ctattccttg
    14101 aaggaagctg ccaataccct accgtatgat atggtggaat tggtaagaag aaattagtta
    14161 atactcttcg aaaatctctt caaaccacgt cagcgtcgcc ttaccgtatg tatgtgactg
    14221 acttcgtcag tcttatctac aacctcaaaa cagtgttttg agcagcttgc ggctagcttt
    14281 ctagtttgct ctttgatttt cattgagtat aagattataa gtgaaggagt atgacatgaa
    14341 aaagtggtgg aaagagctga tagacaaacc tttattaaaa gcttttttgc attattatca
    14401 agcatcagat agtgagttga ccagtgtcgc agtagcctac tattggttga tttcgatttt
    14461 ccccctgctt ttggtggtgg tcaatatcct cccctatttt cagattcctg tgggagaatt
    14521 tctgggcttt atgaaagacg tcctgccccc aagcctctat gaaggtgtgg aaaaaatagc
    14581 cagagaagtc ttgacgcaac cttcaacagg tttattgagt ttttctgttt tatcggcgtt
    14641 atggagtttt tcaaaatcta tgaatttctt gcaaaaagct tttaacaagg cttatggcgt
    14701 cgaaaagagt cgtggactta tttcccatca gatgctaagt ctcctagtca gttttggctt
    14761 gcagctcctc tttgcgtttg ccttgttttt gatcttattt ggtcagatga ttttggcttt
    14821 acttgctcat tattggacaa aagatggcat tatctatcag gctttacaag ggttggcagg
    14881 tcctctgatt tacgccctcc tctttgctat cttggtcatg ctttattatt ttcttcccaa
    14941 tctatctaac aggaaaatta gctataccct accaggcagt gcctttgttc tcttagtgat
    15001 tttaggttta ctaactctgt tctctagtta tctcaattac tatgtccatc atttggtgga
    15061 tgtccgaatt ttaggttccg ttcttcttgt tgttatgatg ttttggttta tcttgattgc
    15121 taaaattgtt atcctaggcg cggttatcaa tgccagtatg cagagtttga aagatccggt
    15181 ctttaaaaaa gactaactat ttatccatta taaaagcgca tagtatcaag actttataga
    15241 accttgatac tatgcgcttt tgtgctttga cagttttttg tatagttttt gtccaagatt
    15301 tctaaatcat ctgattaaat tcctattttc ccctatcatt gtccctgttt tttcgaaaat
    15361 ggaaggagta taataaatct atcaataaaa tgataggagg aactttatgg gtcatatttt
    15421 cttttttcta agtgtctttt tggcagggat tctatccttc ttttctcctt gtatcttacc
    15481 tttgttaccg gtctatacag gagtgttact agatgataag gatggtgctc aggcttctag
    15541 cggcaaattt tcaatctcag ttactagttt attacgaact ctggccttta tagcaggaat
    15601 ttcctttata tttattttgt tgggctatgg agctggtttt ttaggcgatt tgctttatgc
    15661 ttcttggttc caatatctta ctggggcaat tattatcctt cttggtttgc accaaatgga
    15721 gattctacac tttaaggggc tttataagga aaagagacta caactgcaag gacaggggca
    15781 aaatggtaag ggctatagtc aggcattttt attgggcttg acctttagtt ttgcttggac
    15841 gccttgcgtg gggccggttc tggggtctgt tttggccttg gcggcttcag gtggttcagg
    15901 agcttggcag ggagctggtc tcatgttggt gtatacgctg ggcttggcgc taccattctt
    15961 gcttctagct ctgacctcta gttatgtttt gaaacatttc cgaaaacttc atccctatct
    16021 cggaatcctc aaaaaagtgg gtggttttct cattattgtg atgggactct tggttctgtt
    16081 tggaaatgct tcaattttaa gtcaattatt tgaataaaat ggaaaggaat atcaatatga
    16141 aaaaatggca aacatgtgtt cttggagcag gttcgctcct ttgtttgacg gcttgttcag
    16201 gcaagtccgt gactagtgaa caccaaacga aagatgaaat gaagacggag cagacagcta
    16261 gtaaaacaag cgcagctaaa gggaaagagg tggctgattt tgaattgatg ggagtagatg
    16321 gcaagaccta ccgtttatct gattacaagg gcaagaaagt ctatctcaaa ttctgggctt
    16381 cttggtgttc catctgtctg gctagtcttc cagatacgga tgagattgct aaagaagctg
    16441 gtgatgacta tgtggtcttg acagtagtgt caccaggaca taagggagag caatctgaag
    16501 cggactttaa gaattggtat aagggattgg attataaaaa tctcccagtc ctagttgacc
    16561 catcaggcaa acttttggaa acttatggtg tccgttctta cccaacccaa gcctttatag
    16621 acaaagaagg caagctggtc aaaacacatc caggattcat ggaaaaagat gcaattttgc
    16681 aaactttgaa ggaattagcc taggaggtgt cttatgaatg ataagttaaa aatcttcttg
    16741 ttgctaggag tattttttct agccataacc ggtttctatg ttctattgat acgaaatgca
    16801 gggcagacag atgcctcgca aattgaaaag gcggcagtta gccaaggagg aaaagcagtg
    16861 aaaaaaacag aaattagtaa agacgcagac ttgcacgaaa tttatctagc tggaggttgt
    16921 ttctggggag tggaggaata tttctcacgc gttcccgggg tgacggatgc cgtttcaggc
    16981 tatgcaaatg gtagaggaga aacaaccaag tacgaattga ttaaccaaac aggtcatgca
    17041 gaaaccgtcc atgtcaccta tgatgccaag caaatttctc tcaaggaaat catgcttcac
    17101 tatttccgca ttatcaatcc aaccagcaaa aataaacaag gaaatgatgt ggggacccag
    17161 taccgtactg gtgtttatta cacagatgac aaggatttgg aagtgattaa ccaagtcttt
    17221 gatgaggtgg ctaagaaata cgatcaacct ctagcagttg aaaaggaaaa cttgaagaat
    17281 tttgtggtgg ctgaggatta ccatcaagac tatctcaaga aaaatccaaa tggctactgc
    17341 catatcaatg ttaatcaggc ggcctatcct gtcattgatg ccagcaaata tccaaaacca
    17401 agtgatgagg aattgaaaaa gaccctgtca cctgaggagt atgcagttac ccaggaaaat
    17461 caaacagaac gagctttctc aaaccgttac tgggataaat ttgaatccgg tatctatgtg
    17521 gatatagcaa ctggggaacc tctcttttca tcaaaagaca aatttgagtc tggttgtggc
    17581 tggcctagtt ttacccaacc catcagtcca gatgttgtca cctacaagga agataagtcc
    17641 tacaatatga cgcgtatgga agtgcggagc cgagtaggag attctcacct tgggcatgtc
    17701 tttacggatg gtccacagga caagggcggc ttacgttact gtatcaatag cctctctatc
    17761 cgctttattc ccaaagacca aatggaagaa aaaggctacg cttatttact agattatgtt
    17821 gattaatact cttcgaaaat ctcttcaaac cacgtcagcg tcgccttacc gtatgtaggg
    17881 ttactgactt cgtcagtttt atctacaacc tcaaagctat actttgagct gacttcgtca
    17941 gttttattta caacctcaaa gctatacttt gagaaacctg tggctatctt cctagtttac
    18001 tttttgattt ttattgagta taagaggtct ttcctaagca gttagaggag aattttgcta
    18061 tactgatact agtaagtgac aaaggagaga agcatgacct acacaatctt aatcgtagaa
    18121 gatgaatatc tggtaagaca aggtttgact aaactggtca atgtagcagc ctacgatatg
    18181 gaaatcatcg gtcaggctga aaatggaagg caggcttggg aattgatcca aaagcaggtg
    18241 ccagatatca ttttaaccga tatcaacatg cctcatctaa atggcatcca gttggccagt
    18301 ctggtacgag aaacctatcc tcaggttcat ttggtctttt taacaggtta cgatgatttt
    18361 gattatgcct tgtctgctgt caaactaggt gtggacgact acctgctcaa acccttttct
    18421 cgtcaggata ttgaggaaat gttggggaaa atcaaacaaa aactagacaa ggaagagaaa
    18481 gaagagcagt tacaagattt attgactaat aggtttgaag gaaacatggc ccagaaaatc
    18541 cagtctcatc tggctgatag ccaatttagt ttaaagtctt tagccagtga cttaggtttt
    18601 agtccgacct atctgagttc cttgattaag aaagagttgg gcttgccttt tcaggattat
    18661 ctggtgagag aacgtgttaa acaagccaag ctcttgcttt taactacaga tctgaagatt
    18721 tatgagatcg cagagaaggt tggttttgaa gatatgaact attttaccca acgttttaag
    18781 cagattgcag gtgtgacacc tcgtcagttt aagaagggag aagaccgatg aagcgttctt
    18841 ctcttttagt tagaatggtt atttccatct ttctggtctt tctcattctc ctagctctgg
    18901 ttggaacttt ctactatcaa tcaagttctt cagccattga ggccaccatt gagggcaaca
    18961 gccaaacgac catcagccag actagccact ttattcagtc ttatatcaaa aaactagaaa
    19021 ccacctcgac tggtttgacc cagcagacgg atgttctggc ctatgctgag aatcccagtc
    19081 aagacaaggt cgagggaatc cgagatttgt ttttgaccat cttgaagtca gataaggact
    19141 tgaaaactgt tgtgctggtg accaaatctg gtcaggtcat ttctacagat gacagtgtgc
    19201 agatgaaaac ttcctctgat atgatggctg aggattggta ccaaaaggct attcatcagg
    19261 gagctatgcc tgttttgact ccagctcgta aatcagatag tcagtgggtc atttctgtca
    19321 ctcaagaact tgttgatgca aagggagcca atcttggtgt gcttcgtttg gatatttctt
    19381 atgaaactct ggaagcctat ctcaatcaac tccagttggg gcagcagggc tttgccttca
    19441 ttatcaatga aaaccatgaa tttgtctacc atcctcaaca cacagtttat agttcgtcta
    19501 gcaaaatgga ggctatgaaa ccctacatcg agacaggtca gggttatact cctggtcaca
    19561 aatcctacgt cagtcaagag aagattgcag gaactgattg gacggtactt ggcgtgtcat
    19621 cattggaaaa gttagaccag gttcggagtc agctcttgtg gaccttgctt ggggccagtg
    19681 tcacatctct tcttgtctgt ctctgcttag tgtggttcag tcttaaacgc tggattgctc
    19741 ctttgaagga tttgagagaa accatgttgg aaattgcttc tggtgctcaa aatcttcgtg
    19801 ccaaggaagt tggtgcctat gaactgagag aagtaactcg ccaatttaat gccatgttgg
    19861 atcagattga tcagttgatg gtagctattc gtagccagga agaaacgacc cgtcagtacc
    19921 aacttcaagc cctttcgagc cagattaatc cacatttcct ctataacact ttggacacca
    19981 tcatctggat ggctgaattt catgatagtc agcgagtggt gcaggtgacc aagtccttgg
    20041 caacctattt ccgcttggcg ctcaatcaag gcaaggactt gatttgtctc tctgacgaaa
    20101 tcaatcatgt ccgccagtat ctctttatcc agaaacaacg ctatggagat aagctggaat
    20161 acgaaattaa tgaaaatgtt gcctttgata atttagtctt acccaagctg gtcctacaac
    20221 cccttgtaga aaatgctctt taccatggca ttaaggaaaa ggaaggtcag ggccatatta
    20281 aactttctgt ccagaaacag gattcgggat tggtcatccg tattgaggat gatggcgttg
    20341 gcttccaaga tgctggtgat agtagtcaaa gtcaactcaa acgtggggga gttggtcttc
    20401 aaaatgtcga tcaacggctc aaacttcatt ttggagccaa ttaccagatg aagattaatt
    20461 ctagacccca aaaaggaacg aaagttgaaa tatatataaa tagaatagaa actagctaac
    20521 tcccagtcaa ttctgggagt tttatgcgta attgggcaaa ctttctaggt tgtctatctt
    20581 gctaaaaaca agaaaaaacg gtatgataga agagtgacaa cagaggtaac agagatgaac
    20641 gagacacaga ttcaaagaga aacacgtcag gtagtggaag atgttttaga aaagaccaat
    20701 ttgaaacagg gggccctttt tgttttaggt ctatcttcta gtgaggtgct aggtggtcag
    20761 attgggaaag aatccagtca agagattggt gagctgatag tggagactat cttgggtatt
    20821 ctaggtagta gaggtatcca tttagcagtt caaggttgtg agcatgtcaa tcgggctctc
    20881 gttgttgaac gtcaggtggc agagcagttt ggtctggaaa ttgtcagtgt ccatcctact
    20941 cttcatgcag gaggttcggg gcagttggca gcctttaagt ttatgcagga tccagttgag
    21001 gttgaattta tcaaggctca tgctggattg gatatcggag acactgcaat tggcatgcat
    21061 gtcaagcatg ttcaggttcc gattcgccct attttgagag agattggtca tgcccatgta
    21121 acggcactgg ctagtcgtcc aaaattaatc ggaggtgcgc gtgcgcacta tccgcaagat
    21181 gctattagaa agacctgaga atgaataaag gagataaaag tgtttaaaaa agaccgtttt
    21241 tcaattcgta agattaaggg agttgtaggc tctgtatttc ttggaagcct tttgatggct
    21301 ccttctgtag tggacgcagc cacctatcac tatgtaaata aagagattat ttcacaagaa
    21361 gctaaagatt taattcagac aggaaagcct gacaggaatg aagttgtata tggtttggtg
    21421 tatcaaaaag atcagttgcc tcaaacaggg acagaagcat ctgttttgac agcttttggt
    21481 tatctatcag gtgacatcct caaaacgctt ggcttggaca ctgttttaga agaaacctca
    21541 gcaaaacctg gagaggtgac tgtagtcgaa gttgagactc ctcaatcaac aacaaatcag
    21601 gagcaagcta ggacagaaaa ccaagtagta gagacagagg aagctccaaa agaagaagca
    21661 cctaaaacag aagaaagtcc aaaggaagaa ccaaaatcgg agataaaacc tactgacgac
    21721 acccttccta aagtagaaga ggggaaagaa gattcagcag aaccagctcc agttgaagaa
    21781 gtaggtggag aagttgagtc aaaaccagag gaaaaagtag cagttaagcc agaaagtcaa
    21841 ccatcagaca aaccaacaga ggaaccaaaa gttgaacaag taggtgaacc agtcgagcca
    21901 agtgaagacg aacaggcacc aacggcacca gttgagccag aaaagcaacc agaagctcct
    21961 gaagaagaga aggctgtaga ggaaacaccg aaaccagaag ataaaataaa gggtattggt
    22021 actaaagaac cagttgataa aagtgagtta aataatcaaa ttgataaagc tagttcagtt
    22081 tctcctactg attattctac agcaagttac aatgatcttg gacctgtttt agaaactgca
    22141 aaaggtgtct atgcttcaga gcctgtaaaa cagcctgagg taaatagtga gacaaataaa
    22201 cttaaaacgg ctattgacgc tctaaacgtt gataaaactg aattaaacaa tacgattgca
    22261 gatgcaaaaa caaaggtaaa agaacattac agtgatagaa gttggcaaaa cctccaaact
    22321 ggggttacaa aagctgaaaa agttgcagct aatacagatg ctaaacaaag tgaagtaaat
    22381 tctgagactg caagtcttaa aacagcaatt tctggattaa atacagataa agttgaactc
    22441 gaaaatcaac ttaagattgc acagggaaaa actgaaactg atttcagcat ggaatcttgg
    22501 acggttttga gtacagctaa aaataaagct caggaagtaa aagataacgg aacagcgacc
    22561 caagaacaaa taaacgaagc agagaaaagt ttgaaaacag cccttgctga cttatctgtt
    22621 gacaaaacag ctttgggaag cgctatcgat acagctacca agaaaaataa agagaactat
    22681 acaaatcaaa catgggcaga gttagaaaca gttcttacag cagcaaaatc tgtaaacact
    22741 aacgagtcta aacaaagtga agttaatgaa gctgttgaaa aattaactgc aactattgaa
    22801 aaattggttg aattgtctga aaagccacgt ttgactctat ctattgaaaa gagagacata
    22861 gatcgaaaag ttacggtcac gtatactttg gaaaatccag caaatactca aataaaatca
    22921 ataactgcaa ctctgaaaaa aggagaggaa gttgttaagg attttgtttt aacagaagaa
    22981 aatcttaaaa ctaatcattt aactgctttg tttgaaaagc tagattacta caaagaatac
    23041 actctatcta cggatatggt atataacaga ggaaatgatg atgagacgga gagtatttca
    23101 gaagaactaa ttcagctgaa tcttaagaaa ctagaattga aagatatcca gacagtctct
    23161 ctgatgaaat ttgaaaatgg tcaagaaagt caggttacac acttgtctga taaaccgacc
    23221 gatttgagta aattatactt aaaagttaca tcatcaacgt ctaaggatgc tgtgttagcc
    23281 gttagctcta tagaagaaga gattgttgaa aataaaaaaa tctttaaaat tcatgcagat
    23341 acaccagaat tagtagttcg taagaaagat ggcagtcttt ctaagggatt tgactattac
    23401 atggagagag ttatccctca tgatggtgat atttattatg attttaaaga cttgatttca
    23461 gctatgacat ctaatcctac aggtacgttt attttaggga gagatatttc ctcgcgtaat
    23521 gtaaaaccgg atggaaatgg aaaatcttat atcaaaggtg aatttaaagg aaaactactt
    23581 ggtacaaatg ataatgttag acactcgatc tttgacttag aatatccatt gtttgatact
    23641 ataaaatcag gagtcgtgaa agatattgat ttcaagcatg tcaatatggt attcccagat
    23701 agcaatcaag gagataacgt agcaacaatt gcaagagtaa tcaaagataa gacaaaaatt
    23761 gagaatgtta atgttgaagg ttatctcgag ggtcgagatc atgtagctgg tttagttaat
    23821 aatcttgaag gtaattccga aattgaaaat atatccttta caggaaagat taagtctaaa
    23881 ggtggtaatt ctattacagc aggtattgca ggtagaaata tcttatctcg tgttaaacgt
    23941 gcctatgtaa atgcaaatat tgaagtcctt ggttcaacga attcgagtat gcttgttgca
    24001 gtaaatggta caacattgaa tgctagtgga ggttggggag cctggggaag acttactgag
    24061 tccgttgcta aagggacgtt agaaattaaa cgcagtggac aagctggtgg agttactgca
    24121 acagtctggc cttatggagc aattgataag gttgtcagct atgcaaaagt taccaaagga
    24181 aaagaattat ttgggtcaga tggtgattta aataataatt ggtttatgca aaaaattaat
    24241 aatatttttg gtgttcaagg tatcagctca ggtgactcag ggaatgattc taagtttaag
    24301 cgtatttccg aggaagaagc aaagcaaaag gttgcctctt ataatattac agctcccaac
    24361 ttgatgagcg actcaagtct tttggtagac agactcaatg aaagttggaa aaatactgat
    24421 caatttgaaa gtatacagga ttatcaatcc caaaaccaat taatttacca gaacttgact
    24481 aaatttactc cttattacaa taaagaattt attgttcatg aaggaaatgc tctcactcct
    24541 gaacaggaaa tattgaagac taagaaaatc aaatcgattg tagggttgaa aggaacagag
    24601 ttcgttgtag atggcagtga tattgatact atcatgcttc attttgagga tggtagtcag
    24661 aagcgatata aggtaacctc tactggtaag ttttcgataa ctaatttacc ggaatatcag
    24721 gttgaagatt taaatgtggt gtatacatca gaacatatag tacatccact agattcgtca
    24781 ctgataaata accttgttga agaattgaaa aaagtagaat tgtatacaga gtctacttac
    24841 caagttctag gtattgataa agataatgct aacaaattga atagaactaa gagattattc
    24901 ttagatgagt cattagatgc tgttaaaaca caattgccta cctttgtaaa aacaatgttt
    24961 gaaaatgagt ggttgcacat caatggagaa tctagtggag ctgtcgctgc tttacgacaa
    25021 aaaatcatgg ataataagac ggctatattg cttgctttga cttatatcaa tcgttattat
    25081 gatgttaaat tctcagacta taatattaaa aaactgatgc tctttaaacc aactttccat
    25141 ggtgaaaaga ttgatctatt agatcgatta atccgactag gatcatctgg agaaaataga
    25201 ttaaaaggtt cagaaaatgc agaaacgttc aagcagttat ttgctagcga aacgaagcag
    25261 aaggatttgg tgacttattt agactacaat cgctctttgt tgactaatta tcaaacaaca
    25321 ggggaatggt ttaaagaaac gactaaggat tatattcaat ttgaggaacg tccatcctta
    25381 gtagaggaga ttaaagatgc caaatatcga gtttacgata atttaaccgc accgtattat
    25441 caaggatata tcctacctct cttaacgttg aagaatactc atttagcaat tttatcgaac
    25501 tatagtacta tgacatttgt cagccgtgaa aaacgcccta attggaaaaa tgaagatttt
    25561 gataagtggg tgaaatatgt agcaactgct catagaaacc atgttgatac ttggtataag
    25621 attttacctg ataatatcaa aggtaaaatg gttaaagaga atgttactgc tgtttgggaa
    25681 ggattgagca tcccaggaag tgaatgggta gaccagaatg ctgtagatag aaaaggaaga
    25741 gattacgccc cagctcgaga attctttaat cttgtaggtg gtcctatggg aggttggtat
    25801 gcttaccatg gttatggtgc gcatgctgga ggaagaaatc gggttaatta tgaggtgttt
    25861 gatgtattaa gtgagtatgg tatatcggtc tttactcatg aattgactca cgttaatgat
    25921 acttggattt acttaggagg gtatggtaga cgtgaaaata tgggacctga agcttatgct
    25981 cagggattat tccagtctcc tgttccaggt cagccgggtt ggggggcgct tggtctcaat
    26041 atggcatttg aaagaaaaaa tgatggtgat ctaatttata atgcctcccc aactcaattt
    26101 gaaaatagga aagagttaga tagttatatg aaaaattata acgatactct catgatggtg
    26161 gactacttgg aaggagatgc agttatctct aaaggtaaag aagctattac taaatggttt
    26221 aaaaaagttg aacctaaggt tgttagtcaa acagctcagt atgatacggt tcgtcagttg
    26281 actgctgaag agaaagaaaa actttctgtt tctagtgttg atgatttagt tgatcaagga
    26341 ttaatgtcag acagagctgt aggaaataat acctataatc cagctgattt tgaaacaagt
    26401 tatattgcga tagattatat gactggtatt tatggtggag gaaagaatag tgtaggttca
    26461 ccaggtgcct tgatgtttaa acataatact ttccgtatgt ggggctacta tggttttgaa
    26521 gaaggtgttc taggatatgc ttctaataaa tttaagcaag catctagaga tgaaggtcat
    26581 gctggactta gtgataactt tattatttct aagatttcca aaggggaatt tttaactatg
    26641 gaagcattta aaaagggata ttttaagaaa gtagtagaag agttaaaaac taaaggtatt
    26701 cgtcctgtta ctatcaatca aaaaacatat agcacctttg aagaattgca agaaggattt
    26761 aagcaggctg ttgaaagaga tttgaagaaa aatcagttag atgagaggga aacaagaaac
    26821 ttcaaattcc aagttttcag acaacttctt caacaaacag atagctttaa aacttctatc
    26881 tttagataat cgaaatctct catctgcttt gcggatgagg gttttcttat tttatgctat
    26941 acttaaagta tgcatagaaa aacagtgatt gattttagga ctttggggga gagatatacc
    27001 tttacccagc ctattaaaga gttgaaaacg agaaatgtag aagaagtggc agatttgctg
    27061 gcacaagtgg aaagctacca agagcaaggt tattatgtgg tggggtatgt cagctacgag
    27121 gctgcacctg cttttgagga aaaattagca gttcacaagg atcccctact gggagagtac
    27181 ctgctttatt ttactgttca tgatagcgta gaaacttccc ctattcctct gacttatgag
    27241 gatattgatt tgccctcaaa ttggcaggaa gtaacgtctg cagcagacta tgaaaaggcc
    27301 attgcccaaa ttcaccatca tttacggcag ggagatacct atcaggtcaa ctacaccgtc
    27361 caacttaagc aaaagttaaa tgccaatcct tttgccatct acaatcgtat ggtggtagag
    27421 caggaggcgg gctacaatgc ctatgtggaa catgacgaga tggcagtgat ttccatgagc
    27481 ccagagctct tttttgagca aaatgatcgc gagttgacaa cacgaccaat gaaggggacg
    27541 actcagcgtg gggtaactga ccaagaagat cttgaacagg ccagttggtt ggaacaggat
    27601 cccaaaaatc gctctgaaaa tatgatgatt gtggacctct tgcgcaatga tatgaaccgt
    27661 atttctgaag ttgggagcga gcacgtggag cgtctgtgtc aggtagagca gtattcaact
    27721 gtttggcaga tgacttcgac catcaagagt cagttgcgag aggatgtgga ccttgttgaa
    27781 atcttccact cactctttcc ttgtggttcc ataacgggtg caccgaaaat tgcgacaatg
    27841 gagattatca aggacttgga gcctcaaccg cgtggagtct actgtggaac gattggtctc
    27901 ttgcttccaa atggacgacg gatttttaat gtggccattc gtaccattca acttcacaaa
    27961 ggtcaagcca tttatggagt tggcggaggg attacttggg atagcacttg ggaatctgaa
    28021 taccgtgaag ttcatcaaaa ggcagcagtt ctctatcgta aacaagctcg cttccaatta
    28081 attacaactg gaaaaatcag ccaaaaacaa ctgatgtttg aagaacaaca tctggaaagg
    28141 ctgagaaaag ctagtcggta ttttgcttat ccttttgacc cagaaatttt gagacaaaag
    28201 attgaagcag agtgtcagac ttgtgatgct aatcaagatt accgcttgcg aatttctctc
    28261 agcaagtctg gagagataga attcagtcgt caaatcttaa cacctcttag tccaagtttt
    28321 tgtcaggcca aactttgtct gcaagaagcg aatttgaatc aatcctttac ctattttaaa
    28381 acgacttaca gaccgcattt gagcatagag gaacaagaga agatttacca taatggaaaa
    28441 ggagaacttc ttgaaacctc tatcggaaat ttggttctga aaatcgatgg gaaactctac
    28501 acaccgccta tccgacttgg aatcttgcca ggaatttatc accagtattt actagaaaca
    28561 ggacaggtag aagagaaagt cttgaccttg gcagattttg cccaagcaga agctatttac
    28621 ggctgtaatg cagtgagagg cttgtatgag ttgcaagtga taggattgtg agttttagct
    28681 attaatagtt tttaatatat attaaaatat attggtgttt acttttgatg agatatcata
    28741 tttgtgttat aatgtaaccg taaacaatag aaatttaaag gagatttttg atgaaatcaa
    28801 aaatagtttt gggagcttcg ctagcgatcg caacacttag cttagtatct cttgtcgaga
    28861 ttgaaggact ctcaccgttt ttaatagaga atgttagcgc aaatactcat tctgcaaata
    28921 aagttattaa tcataaagta agtatttact tagaaaatgc tgatgaaggt aaaggtctaa
    28981 ctgtaaactt ttcaacagac agtgttagtc caaatttatt tgatgagttc gaaaaaaaga
    29041 gtggaattac aataactact atgttagtga atgctaagac aggtgaagtt gtagaaaaaa
    29101 gattaacacc aagcgttttt ttacgttcca atgatttaac cagtgggacc atatcttcgt
    29161 ttatttttag tgaatatcct gatggagaat ataaatatgt tgtgtctaaa ggagacttta
    29221 tcgatcctaa gactcagttt aaacatcagt atagaggaga atctccagtt tttagaatac
    29281 gtaatcgaaa atatgtggag ttgggaacaa ctgataaaaa attagatgaa agacgtgata
    29341 atagcgttta taaagatggg gttgttgaac acaaggtaaa tttaagttta acaagttatc
    29401 aaggaggtaa tggagttact gcaatttttt caactgatag tgttaactct aacttactta
    29461 attcttttgg tgaaaaggct aaaaaagttt tgattaggtc taagttaatt aatgttaaga
    29521 ctggcgaggt tattgatgaa acgttttctc caaaagtaag tttaacctct aaaattttga
    29581 aaagtggttc tacagcagta ttttatttta tagatttaac tgatggcgaa tataaatatg
    29641 ttgcgtatga aagccagcaa tatactgatc ctcaaacaac attgactcat cagtatagag
    29701 gagaatctcc tatttttagt atcaaagatg gaaaattttc tggtttagta tctgcctcaa
    29761 aaccagacga aaacccgaag ccaacgccaa aaccggatga gaaaccaaaa ccttcagcac
    29821 cacaacagga gaaaacaaaa cctacagttc agtctggttg ggtaggttca tcttattatc
    29881 aaaatggtaa aaaagtcact agtaagtgga tttttgataa aaaatataat tcatacttct
    29941 atctagatgc atcaggaaat tatgttcaaa acgcttgggt aggtaactat tatctcaaat
    30001 caggcggata catggctaaa agtgagtgga tttatgataa gaactatggt tcatactact
    30061 atctaacatc agaaggcagc tacgctcgta acacttggtc aggcaattat tatttgaagt
    30121 caaatggtaa gatggctaaa agtgagtggg tatacgatag taactacaaa tcatattact
    30181 acttgacatc agaaggaagt tatgctcgta acacttgggt aggcaattac tatcttaaat
    30241 caaacggtaa aatggctgtt aatgaacgta caccagatgg ttatcgtgta gatggttcag
    30301 gtaaatgggt taaataagaa actaaaaaat aggataatag gtaatatcag atgaataaaa
    30361 aaaattattt tcatgtgctt tagcattttc aacgattgga acattgtcaa cgattgataa
    30421 atcaggagtt cttccttttt cagcgcaaac ggtgcaggct gacatacaaa cgcttacccc
    30481 aatggcaaaa tattatatta ttcttccgaa ggatgcagaa atatataaaa cttggagagg
    30541 tactgtcaat attcccatta ttgatgctac aaaaactact ccagaattat cttatttcaa
    30601 agaagatcat cgcaactata tagctaatga gaataagtct ggtgccaatt acatagagtg
    30661 gaagggaaca gtagaagagt ttaaagaggc cattaagaag ttgactgata aaaaatcaac
    30721 tactgcaaca ccaaaaaagg atgaaaagcc aacaccaaaa ccggatgaga agccaaaacc
    30781 aacacctaca gttcagtctg gttgggtagg ttcatcctat tatcaagatg gtaaaaaagt
    30841 cattagtaag tggatttttg ataaaaaata taattcatac ttctatctag atgcatcagg
    30901 aaattatgtt caaaacgctt gggtaggtaa ctattatctt aaatcaggcg gatacatggc
    30961 taaaggtgaa tgggtttatg atgccaccta tcaagcttgg tattatttga catcagatgg
    31021 ttcttatgct tacagtacat ggcaaggaaa ttactatcta aaatcggatg gtaaaatggc
    31081 tgtcaatgaa tgggttgatg gtggacgtta ttatgttggc gctgacggag tttggaagga
    31141 aggtcaagca agtacagctt cttctagtaa tgatagcaat agtgaatatt ctgctgcttt
    31201 aggaaaggca aaaagttata attcgttatt ccacatgtca aaaaaaaacg tatgtataga
    31261 caattaactt ctgattttga taaattttca aatgatgcag ctcaatatgc cattgatcat
    31321 tagatgatta acagatactg gtaggcgaaa aaattcctta taattcattt acgcaaacct
    31381 ttgcataagt gaatggattt tgatatacta gtactgtaag cattttcaat tactacacaa
    31441 tgaaaaagga gaatatgatg agtcaaaaga ttattgggat tgaccttggt ggaacttcta
    31501 tcaaatttgc aatcttaaca acagcaggag aaatccaagg aaaatggtca atcaagacca
    31561 acattttgga tgagggaagt catatcgttg atgatatgat tgagtctatt caacatcgtt
    31621 tggacttgct tggattggca gcagcggact tccaaggcat tggaatggga tcaccaggtg
    31681 tggttgaccg tgaaaaaggg actgttatcg gtgcctacaa cttgaactgg aaaacccttc
    31741 aaccaatcaa acaaaagatt gaaaaagcct tgggcattcc atttttcatc gataatgatg
    31801 ccaacgtagc agctcttggt gagcgctgga tgggtgctgg agataaccaa ccagacgttg
    31861 tctttatgac actcggtact ggtgttggtg gcggtatcgt cgcagaaggc aaattgcttc
    31921 acggtgttgc tggtgcagca ggtgagttgg gccacatcac tgttgacttt gaccagccaa
    31981 ttgcatgtac ttgcggtaag aaaggctgcc ttgagacagt tgcttcagca acagggattg
    32041 tcaacttgac tcgtcgctat gccgatgaat acgaaggcga tgcagccttg aaacgcttga
    32101 ttgataacgg agaagaagta actgctaaga ctgtctttga gctcgcaaaa gaagaagacg
    32161 accttgcttt gattgtttac cgtaacttct cacgttactt gggtattgca tgtgctaaca
    32221 ttggttcaat cctaaaccca tcaacaatcg tcatcggtgg tggtgtgtca gctgcaggag
    32281 aattccttct acaaggtgtt caaaaagtct acgatgaaaa tagtttccca caagtacgca
    32341 catctactaa attagcactt gcaactctag gaaatgacgc tggagttatc ggagcagcat
    32401 cacttgtatt gcaataagat aatgagagag gaaaatgcta acctagagtt agtaatgttc
    32461 ctcttttatt ttttatgcta tactagttag gacaatgaat gaggtgaaac gaaatgacaa
    32521 aagcagatac gatttttaaa gagaatattg aacgcattct aaaggaaggt gttttctcag
    32581 agcaggctcg tcctaagtac aaggatggga ctgttgctaa ttccaagtat gtaactggtg
    32641 ccttttccga gtacgactta tctaaaggag aatttcctat cacaaccttg cgtcccattg
    32701 caatcaaatc cgccatcaaa gaagttctct ggatttacca agaccagtca aatagcttag
    32761 aagtgcttaa tgacaagtac aatgttcact actggaatga ctgggaagtt ggagacacgg
    32821 gaaccattgg tgagcgctat ggtgccgttg ttaagaaaca cgacattatc aataagcttc
    32881 tcaaacagtt ggaaaccaat ccttggaacc gccgcaatat tatttcgctc tgggattacc
    32941 aagctttcga agaaacagat gggctgctcc cgtgcgcctt tcagaccatg tttgatgtcc
    33001 ggcgtgttga tggggaaatc tatctggatg cgaccttgac ccagcgctcc aatgatatgc
    33061 tggtggccca ccacatcaac gctatgcagt atgtggcttt gcagatgatg attgccaaac
    33121 attttggctg gaaggttggg aagttcttct acttcatcaa caacctccat atctatgata
    33181 atcaatttga acaagctcag gaattgctcc gtcgggagcc gtcaaactgc caaccacgct
    33241 tggttttaaa tgttcctgat gggactaatt tctttgatat caaagcagaa gattttgagt
    33301 tggtggatta tgaccctgtt aagccacagt tgaagtttga cctagctatt taaaagaata
    33361 gaaaaaagaa gttgagaata atcccaactt cttttgtttc ttaacgtgat acgcggcgac
    33421 gagctgcttt tttacggttt tcttcgatga aagctgcttt ttgctcttct ggttcgatta
    33481 ctttcttttt aaatgcgtat actgcacctg caacggcagc gacagttcct gcgacacctg
    33541 ttacaagacc tttagcgaat cctttagcca tgagtcttcc tcctttatat tctcaatcag
    33601 ccagcctcct caagaggtca catttttctg actgaccttt ttgtgttata ataatagtaa
    33661 cgaaaaaatg ggaatttttc aaggaaaaaa gatgaaaaca aaaataattg tgattgttgg
    33721 accgactgct gttggaaaga cggctctagc tattgaagtt gcaaagcgct ttaatggcga
    33781 agtggttagt ggagatagcc agcaagtcta tcgaggactt gatattggga cggccaaggc
    33841 tagtccagaa gagcaggcag ctgttcctca tcatttaatc gatgttagag agataaccga
    33901 gtcttactcg gcttttgatt ttgtttcaga agctaagatg actattgagg atattcagag
    33961 ccgtggcaag ctagccatta tcgccggtgg gactggactt tatatccaga gcttgctaga
    34021 aggttaccac ctaggtgggg agactcctca tgaggagatt ttagcttatc gagctagttt
    34081 ggagccatat tcagatgagg aattagccca tttggtggag caagcaggcc ttgagattcc
    34141 ccagtttaat cgtcgtcgtg ctatgcgtgc cttagaaatt gcccattttg gtcaggattt
    34201 ggaaaatcaa gagatcttgt atgaaccgct gattatctgc ttggatgatg aacgtagtca
    34261 actttatgag cgtatcaacc accgagtgga tttgatgttt gaggctgggc ttttggatga
    34321 ggccaagtgg ctgtttgacc attcccctaa tgtacaggct gctaaaggaa ttggctataa
    34381 ggaactcttt ccttatttcc gtggagagca gacctttgag gaagctcgtg agagtcttaa
    34441 acaggcgacc cgtcgttttg ccaagcgtca gctgacctgg ttccgtaatc gcatgcaggt
    34501 caccttttat cagattggag aatctggtgt acaagaccgc attttaagcc agatagagga
    34561 gtttttagat gattgaaacg gagaaaaaag aggagcgagt cctgctgatt ggtgtggaat
    34621 tgcagggtat ggacagtttt gacctctcca tggaagaatt ggctagttta gcgaaaacgg
    34681 caggggcagt cgttgtagat agctacagac aaaaacgtga aaaatatgat tccaagacct
    34741 tcgtcggctc tggtaagttg gaagagattg cgcttatggt ggatgcagaa gaaatcacta
    34801 ctgtcatcgt caacaatcgt ctgaccccaa ggcagaatgt caatctagag gaagttctcg
    34861 gtgttaaggt cattgaccgt atgcagttga ttttggatat ctttgccatg cgggctcgaa
    34921 gccatgaagg gaagctccaa gtccacctag cccaactcaa atacctcttg cctcgcttgg
    34981 ttggtcaggg gattatgctc agccgtcagg cagggggaat tggttcccgt ggtcctggtg
    35041 aaagccaact ggagctgaac cgtcgtagcg ttcgcaatca aatcacggat atcgagcgcc
    35101 agcttaaggt ggttgagaaa aatcgtgcga ctgtcagaga aaaacgtttg gagtctagca
    35161 cttttaagat tggtttgatt ggttatacta atgctgggaa atcaactatc atgaacatct
    35221 tgaccagtaa gacccagtat gaagcagatg agctctttgc gactctggat gcgacaacca
    35281 agagtattca tctgggaggc aatctccaag taactttgac agataccgtt ggctttatcc
    35341 aagatttgcc gacagagttg gtgtccagtt tcaagtcaac cttggaagaa agcaagcatg
    35401 tggaccttct ggttcatgtt atcgatgcta gcaatcctta ccacgaggag catgaaaaaa
    35461 cggttctctc catcatgaaa gacctggaca tggaagatat tcctcacttg acgctttata
    35521 ataaagcgga tttggtggag gatttcacgc ctacccaaac gccatatacc ctcatttctg
    35581 ccaagtctga ggacagtcgt gaaaacttgc aagcattatt gctagataag attaaggaaa
    35641 tttttgaagc atttaccctg cgagtgcctt tttcaaagtc ctacaagatt catgatttag
    35701 agagtgttgc aattctggaa gaacgtgatt atcaggaaga cggcgaagtg attacaggct
    35761 acatttccga gaaaaataaa tggaggttag aagaatttta tgactgatat taaaactttg
    35821 gctctaaagt atggaggtta tacaagtctg gacaaggtct atctggatca gcttctagct
    35881 ggtaaaacag atcaggagca gttaacactt attacacctc cgccaagtgt tgttaatgcc
    35941 tactttgcag aactctatca gaaaaagagt cctcaggctg cgacggatta ttttgcagaa
    36001 ctcagtcagg aactgaatct ttacaatact gagccaagtt tcaccctaga aaataagcct
    36061 tttattcggc ttaatctgtc tggtaaatcc tttggttttt gttatgagag tgacggcctt
    36121 ggtcggattt tctttgaaaa tgaggagaaa atctcggatg acttgctctt tgaaattgcg
    36181 caaattttcc cccatcaatt agtctttgaa gagtctggta agatttacat gaagcctgtc
    36241 gaggacgagg aagttatcag cctagaaagt ctcacagctt tgactgattt ggaaagattg
    36301 actgatggtc gaaaacgtct caaaggctac agccaagagg atttattgca agaagctgct
    36361 gctttttctg gcaaacgcta tttccgatcg gaaaaccgca cagccatgtt atatattgat
    36421 taattagaaa gtatcgaatg gatattcaat ttttaggaac gggggctggt cagccctcta
    36481 aagcccgcaa cgtttcaagt ctcgccctga aacttttgga tgagattaac gaagtttggc
    36541 tctttgactg tggagaaggt acgcaaaatc gcattctgga aaccacaatt cgaccacgta
    36601 aggtcagcaa aatctttatt acccatctgc atggagacca catttttggt ttgccaggtt
    36661 tcctttctag ccgtgccttt caggccaatg aagagcagac agatttggaa atctacggac
    36721 ctcaaggaat caagtcattt gtcttaacca gccttcgtgt gtcaggttct cgtctgccct
    36781 accgcattca tttccatgag tttgaccaag attctctggg taaaattctt gaaaccgata
    36841 aattcactgt gtatgcagag gagctggacc acactatttt ctgtgttggc tatcgtgtca
    36901 tgcaaaagga tctagaaggg acgctggatg ctgaaaaact caaggctgct ggtgttccgt
    36961 tcggcccgct ttttggtaaa atcaaaaacg gccaggatct tgttttggaa gacggaactg
    37021 aaatcaaggc agcagactat atctcagcgc cacgtccagg taagattatc actattttag
    37081 gagacactcg aaaaacgggt gccagtgtgc gtctggctgt caatgcagat gtcctagttc
    37141 atgagtccac ttatggcaag ggtgatgaaa aaattgctcg taaccatggt cactcaacta
    37201 atatgcaagc tgcacaagta gcggtagaag caggtgccaa acgcctccta ctcaaccata
    37261 tcagtgcccg tttcctctca aaagatatta gcaaactcaa gaaagacgct gccacaattt
    37321 ttgaaaatgt ccatgtggtc aaagacttgg aagaagtgga aatctagcag tcacagaaag
    37381 gataagtatg cctactattc tcattaccgg agctagcggt ggtctagctc aagaaatggt
    37441 caaactcctg cccaatgacc aactcatctt gcttggtaga aataaggaaa aattagccca
    37501 actctacgga aattattccc atgcagaatt gattgaaatt gatattaccg acgattcagc
    37561 cctagaagct ctggtaactg atctttatct ccgctatggc aagattgatg tcttgattaa
    37621 caacgctggt tacgggattt ttgagggatt tgaccagatt gctgataaag atattcacca
    37681 gatgtttgag gtcaatacct ttgccctgat gaatctgtct cgtcaccttg cggctcgtat
    37741 gaaggaaagc agcaaagggc atatcatcaa catcgtcagc atggcaggtc taatagctac
    37801 tggcaagtct agtctttact cagcgaccaa gtttgcggct attggttttt caaatgctct
    37861 gcgactcgaa cttatgccct atggagtcta tgtgacaaca gtcaatccag gtccaatccg
    37921 aacaggattt ttcgaccaag ccgacccaga tggaacttat cttaaatcgg ttgaccgctt
    37981 cctgctagaa ccagatgcag tggctaaaaa gattgtcaag attataggaa aaaacaaacg
    38041 agaactcaat ctcccgattt tgttgaacct agctcataag ttttataccc tctttcctaa
    38101 gctagctgat aagttggcag gggaaacttt taattataag taaaaagaac caatgtgcag
    38161 gttgttgcta gcctacatat tggttcttat catttctcaa ctatcaaact gaacttcttc
    38221 tagtagatag tcgataaagc gttcgcccat cttagatagg ctggttttct catgctggat
    38281 atagaccagc tcaatcgggt catcaatatc cagtgggata gaaacgatat tgtctccgtt
    38341 taggttgctg ttcaaaatcc ctgtcgcaat ggtataacca tccaaaccaa tcaagagatt
    38401 aaagagggtg gcacggtcac tgaccacaat ggatttcttg tggtgttctt gagaaagaat
    38461 ctcttctgaa aagtagaagg agttgtgcgt cccttggtca tagctgaggt aagggaaatt
    38521 ctccaaatca gacagtttca ccttgtcttt ctttgccaga gggttggtct tgctgacaaa
    38581 gatatgcggt tgcgctgtga agagatggtg ggctagcagg tgattgtcat ccagcatctt
    38641 ggttaaaaca tcacggttgt aactgtttaa gaagaggacc ccgacctcac tgcggaagtt
    38701 cttgacgtcg tcgataatct cccaagtccg agtttcacga aggaagagtt cgtatttctc
    38761 catatcgctt ttcttgagca aagagacaaa ggcattgacc acaaaggcat agtgttgaga
    38821 cgaaacgcta aagagttcgc ggtgtgcgac aggattttta tagcgttcct ccagaagctg
    38881 ggtctgctcg acaacctgac gggcataaga gagaaactcc atcccatcac gggtcaaggt
    38941 gattcccttg ggattgcgga taaagatctc aatgcccatt tcattttcca aatctctcac
    39001 agcattggaa agacttggct gagtgataaa gagttgcttg gctgcctcat tcatggagcc
    39061 agtttcgacg attttgataa tataatgtaa ttgttgaatt ctcatgtttt tattgtacca
    39121 cacttgcctt agaatcgcta aagaagatag gaaaataagg agcattgtgt gagtctcttc
    39181 ttgaaaaaaa cacaaaattt tgctagaatg agtcttatga aaacattcta tgatgtgcaa
    39241 caattcctca aacgatttgg tattattgtt tacatgggaa aacgcttata tgatattgaa
    39301 ctgatgaagt tggaactatc tcggatttac gatgcagggt tgatggataa attagactat
    39361 ctagaggcag aagcagttct tcgcagagag cacaaggtag aattggatta tattgagaaa
    39421 aatggagaaa agaactaatg gttacttgga ttttgtgggc acttatacta gcaatgttgg
    39481 cgtggatggg ctttaactat cttcgtattc gccgtgcggc taaaattgtg gacaatgagg
    39541 agtttgaagc cttgattcgt acgggtcaat tgattgattt gcgcgaccca gcagaattcc
    39601 acagaaaaca tatccttcgt gcacgcaata ttccttcaag tcagttgaaa actagtcttg
    39661 cagcccttcg taaagataaa cctgtccttc tctacgagaa ccaacgtgcg caacgagtta
    39721 caaatgcagc tctttacttg aaaaaacaag gtttttctga gatttatatc ctttcttatg
    39781 gcttggattc ttggaaaggg aaagtgaaga ctagctaacc ttatttccaa attagtcgaa
    39841 tgataggatg aagctattgt tttatagtat aattaatttg tataaaattt aaagagttct
    39901 tagaacatga aagaaaagaa gaaaaatcca ctttttgtgg gtatcttgtc gattattctt
    39961 ggtttgttat ttccaattgt aggcctgatt ttgggtatca taggattggt cttggctatt
    40021 tcataccaaa aagagtcaca attagactat aaaatagaaa agattcttaa tatcttagga
    40081 attgtgattt ctgtagttaa ctggattgta gcaatcgcct taatttttcg ataaataaaa
    40141 gaaaaaagct ttagttttaa agcttttttt gttttatcga ctcatctcta aatagttttt
    40201 aatgatttgt aactcttttt ggttcaaagg gcggtagtta ccttctgcta aatctgggtt
    40261 caatgtgaag tccccaaatt ggattctctt gaggctagtc accttaacac caaccgagag
    40321 gaacattttc ttgatttgat gaaattttcc ttctgaaatg gtgatagagg cttgactgat
    40381 ggagggactt gcagatagaa tctctagttt tgcgggttta cagacagtac catctaaaaa
    40441 gacaattccc ttttgaaagg cttggatatg gtcaggtgtt agaagtccat taacctcaac
    40501 ttgataagtc ttatcgacat gatattgggg atggaggagt tggaagccca agggaccgtt
    40561 atcggtcaag agaaggagtc ctgttgtatc tcggtccagt cggccgacgg catagagctt
    40621 gtcagactgg atgtcagatg gaagcaggtc catgacggtc ggaagttcct tgtctttgtt
    40681 ggctgtaacg acaccagcag gtttatgaag cataagatag gtgtgttcat agccttgaat
    40741 gattcgatcc tgaaaaagga gttcttgtag tcctgtatcg atattttggg ctagggatcg
    40801 ggctgggcaa ctatcgacga gaatttcccc tctgaggagt gcttgcttca tggcctttcg
    40861 gctgattttt tcttgagcta ataaattatc taaacgcata ctgtgcctat cttatcataa
    40921 gtcgcttgct ttgaaaaggc ttgacgtgaa aagaaaagcg gagtgaaaac atttacactt
    40981 gcttgagtta tgttatttat ttgaaattat ggtataatcg ttcagttaga aaataaattt
    41041 tgaatattat agaggaaatc atgacaaaat taagagaaga tatccgtaac attgcgatta
    41101 tcgcccacgt tgaccacggt aaaacaaccc tggttgacga attattgaaa caatcagaaa
    41161 cgcttgatgc acgtactgaa ttggcagagc gtgctatgga ctcaaacgat atcgaaaaag
    41221 agcgtgggat taccatcctt gctaaaaata ctgccgttgc ttacaacgga actcgtatca
    41281 acattatgga cacaccagga cacgcggact ttggtggaga agttgagcgt atcatgaaaa
    41341 tggttgacgg tgttgtcttg gtcgtagatg cctatgaagg aaccatgcca caaactcgtt
    41401 tcgtattgaa aaaagccttg gaacaagacc ttgtcccaat cgtggttgtt aacaaaatcg
    41461 ataagccatc agctcgtcca gcagaagtag tggatgaagt cttggaactt ttcatcgagc
    41521 ttggtgcaga tgacgaccag cttgatttcc cagtggttta tgcttcagcg atcaacggaa
    41581 cttcttcatt gtcagatgat ccagctgacc aagaagcgac tatggcacca atctttgaca
    41641 cgattatcga ccatatccca gctccagtag ataactcaga tgagcctttg cagttccaag
    41701 tgtcgctttt ggactacaat gacttcgttg gacgtatcgg tatcggtcgt gtcttccgtg
    41761 gtacagttaa ggttggggac caagttaccc tttctaaact tgacggtaca actaaaaact
    41821 tccgtgttac aaaactcttc ggtttctttg gtttggaacg tcgtgaaatc caagaagcca
    41881 aagcgggtga cttgattgcc gtttcaggta tggaagacat ctttgtcggt gaaaccatca
    41941 ctccgacaga tgcagtagaa gctcttccaa tcctacacat cgatgagcca actcttcaaa
    42001 tgactttctt ggtcaacaac tcaccatttg ctggtaaaga aggtaaatgg gtaacttctc
    42061 gtaaggtgga agaacgcttg caggcagaat tgcaaacaga cgtttccctt cgtgttgacc
    42121 caactgattc accagataaa tggactgttt caggacgtgg agaattgcac ttgtcaatcc
    42181 ttatcgaaac aatgcgtcgt gagggctatg aacttcaagt atctcgtcca gaagttatcg
    42241 taaaagaaat cgacggtgtt aaatgtgaac catttgaacg tgtacaaatc gacactccag
    42301 aagaatacca agggtctgtt atccaaagcc tttctgaacg taaaggtgaa atgttggata
    42361 tgatttcaac tggtaatggt caaactcgtt tggtcttcct tgttccagcg cgtggtttga
    42421 ttggatactc aactgagttc ttgtcaatga ctcgtggtta cggtatcatg aaccatacct
    42481 tcgaccaata cttgccattg attccagggg aaattggtgg acgtcaccgt ggtgcccttg
    42541 tttctatcga tgctggtaag gctacaactt actcaatcat gtctatcgaa gaacgtggta
    42601 cgatctttgt caacccaggt actgaggttt atgaaggaat gatcatcggt gaaaactctc
    42661 gtgaaaatga cttgacagtt aacatcacga aggcaaaaca aatgaccaac gttcgttcag
    42721 ctactaagga ccaaacagct gttatcaaga cgcctcgtat cttgacactt gaagagtctc
    42781 ttgagttctt gaacgacgat gagtacatgg aagtaacgcc tgagtctatc cgtttgcgta
    42841 aacaaatcct taacaaagca gagcgtgaga aagctaacaa gaagaaaaaa tcagctgaat
    42901 aagagctaga aagagagaaa gatggtctat ttagtcctag gaattttact gctcctactc
    42961 tatgtatttg cgacaccaga aagcattaaa gggactgtca atatcgtcgc tatggtatgt
    43021 attttagtgg cactcttgat tttattggtt ctatcttttc tgaaaatttt tcaattacca
    43081 acagaaatat tcctagcaat agccatgttg atcctagctt actttagtgt gagagacatc
    43141 acactcatgc cagtcaaaaa aagtaaaaga agataaaaaa gagagttttg gctctctttt
    43201 ttgctaggaa ttttacaaga ttgcaattta tttttgagtt atcaccatct cttttgtttg
    43261 gataatatga atgggaaaaa cttgaataaa attctttaat ggaatctatt ttatatttgc
    43321 ttagtactgg ttgcatatta ttttgaaata aaactactat ataatattat tcatagagat
    43381 aatatagtaa aacatctaaa aaattcgatt ttttccttga caacaaataa taaaaatgtt
    43441 attcttatca cataagaaag cgatttcaac aaaagagaga ggaggattta ttttgttgca
    43501 ttgttgctca aggtgtgatt tttttgaaag aaaaaataaa atgaaaacga aaaaacatag
    43561 attacttgct ctagctctta tttcaaattt tacattattg ggagctgcat cagctgctgt
    43621 acaatatcca gatggaggag tatggacata tggagaaggt tcaggaggtg gttaggcttt
    43681 ttcaaattac tatcatggta aaaaatatca ttattcatcc atcgtgagca gatgggatgg
    43741 tcattctgat aaaggagaag ctcctgctgg aaaaacctcc tatgcatgga tttggactaa
    43801 atggggagaa caagtagcat tttactatga ctatgactaa tatttagttt tcttagataa
    43861 ttccccttgt aagaaattac agggggaatt ttgtttacaa ggagtctact atgaagaaac
    43921 tattcatatt attatcaact ttttttctca gcttcttcct tgcttggatt attgtcttac
    43981 gtgcgccaca atatttatat gcaagctatg attccgtttc tttacttcgt gtcaaaaaag
    44041 atactcagga accgacgcgt gaggtatttg aacaggaatt ggagaatttt gcaaactcag
    44101 aacagagttt aatagctaga agaattgtag agccgagtaa ggatgggacg actcacttta
    44161 cttatgcaac ttatggtcag ggaactttac caaaagaatt ccaagaagct agccaagaaa
    44221 gtcgtgaacg tagtgatccg ctaaatagtt atctcctttt gtcaggctcc ttgacgaaag
    44281 aaaagcttgc cgataaatta ggagatttgg gttataaagc aagtgctgac cgaaagatac
    44341 cgccctattt tcttgctttt cgaatattac taaatcccct tattttaatt agtttagcaa
    44401 tatttggctt atctttcttt gctttagtga ttatcactcg gattaaggaa atgagagcag
    44461 caggtataaa actcttttct ggtcagactc tcttatccat catggggcat tctttatcga
    44521 ctgatatcaa atggctcctt ctatcagccc tcctttcctt cctaggtggg ggagtcgttc
    44581 tttttagtca aggtttgttt tatcctatct tgttagccac ctatggtttt gggattagtt
    44641 tctatctgtt gtttttattg gcgatttcaa ttttactaat gcttctttat ctaatgagtt
    44701 tgaattacaa agcattagtt cccgttatta aggggagatt accccttaaa cgcctgatga
    44761 ttttaaccct attgtgtcag ttagtagctg tttttacagt aggctacgct gttaagacag
    44821 gtttgacgtc ttaccaacga ttgaaagaac ttgaaatttc aaaacaagca tggcaggata
    44881 gagcagacta ttatcaaatt tcttttggct taggtgatag aggaaaagat acagaaaatc
    44941 agagcaagtg gtatgccttt gccaaggaag caatcgaaga agaacaagct ctttatgtaa
    45001 aggataatct gctccatttt gccaatccac aaggaaaaaa tgaacaggga gagacactgg
    45061 atacctatag tccagatgct aatacgctct atgttagtcc cagttatttg gacaaggaaa
    45121 aggtcgtggt agatgctgag accaaacaga agctagccca tctccaaaaa ggtgagttta
    45181 tcctcttgct cccagaacat ttgcgctctc gagaagcaga acttaagaaa gtttttgaag
    45241 aaagattgag ttattatgga aaatctggtg aggaggcaag tgctcctttg gattatgaga
    45301 tgaaagcgca cgttagttat ctttcaatgg gagaaaagcg gtttgtttat aataacggtg
    45361 agaatcccgt atccactcag tatttgactg atccgatttt agtggtattc acgccgactt
    45421 ctacaggtga tagttttata tccttatcta gttggtctat caatgctgga aaacaactct
    45481 ttatcaaagg atatgagagt gggctagaac tcttgaagaa agctggaatt tatgagcaag
    45541 tatcctatct taaagaagga agaagtgttt atctaactcg ttataatgaa gttcaaactg
    45601 aaacagcaac tttaatctta ggagctattg tggggatagc tagttccttg ttactatttt
    45661 attctgtcaa tcttctatat ttcgagcaat tccgccgaga tattttgatt aaacgaattt
    45721 caggtttacg attttttgaa acacatgctc agtatatggt tagccaattt gccagttttg
    45781 tatttggtgc tagtttcttt attttacgca gtagagactg ggtaattggc ttactcactt
    45841 tattagtctt tctagctagt gcagttttga cgctttaccg tcaagcacag aaagaatctc
    45901 gtgtttctat gacaattatg aaaggaaaat aggatgattg aactaaagaa tatatctaaa
    45961 aaatttggaa gccgtcagct attttcagat acgaatcttc attttgaagg tgggaaaatt
    46021 tatgccttaa tcggtacaag tggctgtggt aagacaacac tcttgaatat gattggacga
    46081 ttagagccat atgacaaagg gcaaatcatc tatgatggta cttctcttaa ggacatcaag
    46141 ccttctgttt tctttagaga ttacttagga tatttatttc aagattttgg cttaattgaa
    46201 agccaaactg tcaaagagaa tctcgatctg ggtttagttg gtaaaaagtt gaaggaaaaa
    46261 gagaaaatct ctttgatgaa acaagctcta aatcgtgtaa acctctctta tttggatttg
    46321 aagcaaccta tatttgagtt atcaggagga gaagcacaac gtgttgcact agcgaagata
    46381 attttaaagg atccaccttt gatcctcgca gatgaaccaa ccgcttcctt agaccctaaa
    46441 aactctgagg aattactttc catcctagaa tctttaaaaa atccgaatcg gaccattatt
    46501 attgcgaccc acaatcctct gatttggggg caagtggatc aggtcattcg agttaccgat
    46561 ttatcacata gatgatatgg taagattcag ttagaagaaa gagtcacaaa cacactttgt
    46621 ggctttttta tttccataaa aatggtaaaa tagtaggagt agaaatggag ttcgagacat
    46681 gaaagtaata gatcaattta aaaataagaa agttcttgtt ttaggtttgg ccaagtctgg
    46741 tgaatctgcg gctcgtttgt tggacaagtt aggtgccatt gtgacagtaa atgatgggaa
    46801 accattcgag gacaatccag ctgcccaatg tttgctggaa gaagggatca aggtcattac
    46861 aggtggccat cctttggaac tcttggatga agagtttgcc ctcatggtaa aaaatccagg
    46921 tatcccctac agcaatccca tgattgaaaa ggctttggcc aagggaattc cagtcttgac
    46981 tgaggtggaa ttggcttatt tgatttcaga agcaccgatt attggtatca caggatcgaa
    47041 cggtaagaca accacaacga ctatgattgg ggaagttttg actgctgctg ggcaacatgg
    47101 tcttttatca gggaatatcg gctatcctgc cagtcaggtt gctcaaatag catcagataa
    47161 ggacacgctt gttatggaac tttcttcttt ccaactcatg ggtgttcaag aattccatcc
    47221 agagattgcg gttattacca acctcatgcc aactcatatc gactaccatg ggtcattttc
    47281 ggaatatgta gcagccaagt ggaatatcca gaacaagatg acagcagctg atttccttgt
    47341 cttgaacttt aatcaagact tggcaaaaga cttgacttcc aagacagaag ccactgttgt
    47401 accattttca acacttgaaa aggttgatgg agcttatctg gaagatggtc aactctactt
    47461 ccgtggtgaa gtagtcatgg cagcgaatga aatcggtgtt ccaggtagcc acaatgtgga
    47521 aaatgccctt gcgactattg ctgtagccaa gcttcgtggt gtggacaatc aaaccatcaa
    47581 ggaaactctt tcagccttcg gtggtgtcaa acaccgtctc cagtttgtgg atgacatcaa
    47641 gggtgttaaa ttctataacg acagtaaatc aactaatatc ttggctactc aaaaagcctt
    47701 gtcaggattt gacaacagca aggtcgtctt gattgcaggt ggtttggacc gtggcaatga
    47761 gtttgacgaa ttggtgccag acattactgg actcaagaag atggtcatcc tgggtcaatc
    47821 tgcagaacgt gtcaaacggg cagcagacaa ggctggtgtc gcttatgtgg aggcgacaga
    47881 tattgcagat gcgacccgca aggcctatga acttgcgact caaggagatg tggttcttct
    47941 tagtcctgcc aatgccagct gggatatgta tgctaacttt gaagtacgtg gcgacctctt
    48001 tatcgacaca gtagcggagt taaaagaata atatgaaaaa aattgtcttt acaggtgggg
    48061 ggacggttgg acacgttacc ctcaatcttt tgttaatgcc taagttcatc gaagatggtt
    48121 gggaagtcca ctatatcggg gacaagcgtg gtatcgaaca ccaagaaatc cttaagtcag
    48181 gtttggatgt caccttccat tctattgcga ctggaaaatt gcgtcgctat ttctcttggc
    48241 aaaatatgct ggatgtcttc aaagttggtt ggggaattgt ccaatcgctc tttatcatgt
    48301 tgcgactgcg tccacaggct cttttttcaa agggaggatt tgtctcagta ccgcctgtta
    48361 tcgctgcgtg tgtgtcagga gtgcctgtct ttattcacga atctgacctg tctatgggct
    48421 tggccaataa aatcgcctat aaatttgcga ctaagatgta ttcaaccttt gagcaagctt
    48481 cgagtttgtc taaggttgag catgtgggag cagtgaccaa ggtttcggat caaaaaaatc
    48541 cagaaccaga tgaattggtg gatattcaaa gccactttaa tcataaattg ccgactgtat
    48601 tgtttgttgg cggttctgca ggtgctcgtg tctttaacca attggtgaca gaccataaga
    48661 aagaactaac agagcgctac aatattatca atctaactgg agattctagc ctgaatgagt
    48721 tgagccaaaa tctttttcgt gttgactatg tgaccgatct ctatcaaccc ttgatggaat
    48781 tggctgatat tgttgtgaca cgtggtggtg ccaatacgat ttttgagctc ttggcgatag
    48841 caaaattgca tgtcattgtg ccacttggtc gtgaagctag tcgtggtgac cagattgaaa
    48901 atgcagctta ctttgttaag aaaggctatg cagaagacct tcaagaaagc gatttgacct
    48961 tggatagttt ggaagagaag ctttctcact tactaagtca caaggaagat taccaagcta
    49021 agatgaaagc ttctaaggaa ttgaaatctc tagcagattt ttatcaattg ttgaaaaaag
    49081 atttatcata aggaaagtaa atgtcaaaag ataagaaaaa tgaggacaaa gaaatcctcg
    49141 aagaattgaa agagttatca gaatggcaga aacgaaacca agaatatcta aaaaagaagg
    49201 ctgaagaaga agcggctcta gctgaggaga aggaaaagga aagacaagct cgaatgggag
    49261 aagaatctga gaagtcagag gacaaacagg accaggagag tgaaacagac caggaagatt
    49321 cagaatcagc taaggaagag tctgaagaaa aagtagcatc ctcagaggct gacaaagaga
    49381 aagaagagaa agaagaacca gagtctaaag agaaggagga acaggataaa aagcttgcta
    49441 aaaaggctac aaaggaaaaa ccagccaaag caaagattcc tggtatccat atcttgcgag
    49501 ccttcacgat tttatttcca agtctgcttt tattgattgt ctctgcctac ttgctcagtc
    49561 cttatgcgac catgaaagat attcgtgttg agggaacggt gcaaactaca gctgatgata
    49621 ttcgacaggc ttcaggcatt caggattcgg attatacgat taaccttctg ctagacaagg
    49681 caaaatatga aaagcagatt aagtctaact attgggttga atcagctcaa cttgtctatc
    49741 aatttccaac taagttcact attaaggtca aggaatatga tattgtggcc tactatattt
    49801 ctggtgaaaa tcattatcct attctttcca gtggtcagct tgagactagt tctgtgagtc
    49861 tgaacagttt accagaaact tatatatcag ttctctttaa tgacagcgaa caaatcaaag
    49921 cctttacgtc agaacttgct caaattaacc cagaactcaa ggtggctatc caaaaggtgg
    49981 aattagcccc aagcaaggtg acttccgatt taattcgatt gactatgaat gattcggacg
    50041 aagtcttggt tccgctttct gaaatgagta agaaattgcc ttattacagt aagattaagc
    50101 ctcaattgtc agaaccaagt gtggtcgata tggaagctgg agtctacagc tacactgtag
    50161 cggataaatt gattatggaa gcagaagaaa aagctaaaaa agaggccgaa gaagctgaga
    50221 aaaggcagga agaggaacgt aaacgtttag aagaagaaca gaaaaaacaa gaggaagaga
    50281 gcaatcgaaa ccaaacgacc cagcgctcat cgcgtcgcta ggttttacct tttctcctat
    50341 agctctttag ttgccatgtt tttacgttta atatttgaca tctgtttttc tttatgttat
    50401 atttgcaatg taatcgatta caaaaaaatt ttttatgaag aaggtaacac atatgtcaga
    50461 tgaagtattc ttatttgaag aaattgaaga aatcgtagcc cctacagatg gtgaattttg
    50521 ggggggagtt ttacttggaa ctggggtagt tctcttaatt ggagtagcct gttgttaaaa
    50581 agatagggag tgataatcat gcaagataac tttttatttg aggaaattga agaaatttca
    50641 gtaccagtta gtgatttttc agctggactt gcaacaggta tcggattagg tttagcaatc
    50701 cttgctcttg ctggttgttg aagtttgttc acttactaat atcaagcttt ttcaatttca
    50761 ttttagacag tcatttgaat tttccgtatt agtcttgcag caagagatta atagaattag
    50821 tcattatttt attgattgcg gactgaggga ctagagtatg ttttacttag cccctctttt
    50881 atttattaaa ggttaggttt gttatgagaa ttgttgataa gattaagata ctacctactc
    50941 cttatgaggg acagtatcat ctatatatac catccagtaa gaaacatgta ttagttggga
    51001 aacaggaaaa aaaatggtta gagcaactaa taggtcaaga atttaccata tcggacttat
    51061 tagtgttagt agggaagaaa tattatttaa gattttatat tgttcttagt aaaatgggac
    51121 ttatagattc tatgaaatca cgaaaaaaga taaatatttt taaaatatct tgggacttta
    51181 atataacatt atctgaaaaa ttaaactata aaagatttaa taagaatttt gaaaaaatcc
    51241 tatttggtat tttcccattg gctcttattt tgcaatgttt tattatgtat atttataggg
    51301 cggatatttt gactaatttc caaaactttc caataacgct aaacattctt ttattttggt
    51361 tgcttgttgt tattatatct gcaacgatac atgaatttag tcatgcaata attgctaata
    51421 attatcaaat tgagatccca aattgtggaa taatgctact tttgtttaat ttggcttttt
    51481 ttgtagattt aagtggggtg caattcctaa aaaataaaaa acaatttttg aaaattatgt
    51541 tagcaggaat tgcttcaaat tcgattttat cacttacagg tttacttgtt ttattgttca
    51601 catcgtataa attgcttgga ctcttatttt ttatcattaa cttaggtatg atttttatta
    51661 attcaattcc tttttttcag tatgatagtg gtattatttt aagatacttg aattctaaca
    51721 ataataactt gaattttcaa tatatagttc aacttttaat agcatttgtt attatttatt
    51781 tccctttgag tcaactatta caatttttga cacctaatat tattgttcgt agtataggag
    51841 gggtagttgt ttctatactg ctttctatat tatatatgag aggaaggacg aaatatgttc
    51901 tacgtaaata gttatgtttt tgcttataaa aaagaaggta taatgtattt gcgtggtcgg
    51961 agtatgcggg aaatagctat agaacctcaa atttcgcaag aatttatcaa cgatctattt
    52021 aatagttgta aggaactatt agagatagaa gaagtattag gtagtaaact aacatttgaa
    52081 ctattaaatg aacaaatttt aatttcggat gagatagata ttgatagtag atattctaga
    52141 actaaaggtt actattcgtt attttataat gaagagtata ataaaataca gaataaaaca
    52201 gtattagtat taggagccgg agccttagga tgttatatat ctctaagtct aagtatgtat
    52261 ggagtgagga aacttattgt cgctgattac gatataatag aaccatcaaa tttaaatagg
    52321 caaattcttt atacagagtc ggatgttggt aaggagaaga ttaatgttct ttctcaaaaa
    52381 atacacaagt ataattcaga tgttcaggta gtacctattt ctattaaagt ttcttcagta
    52441 gaagaattag aaaacattgt tgcggaatat gggagtatag attttatcgt taaagcaatt
    52501 gatacgccca ttgatattat aaaaattgtc aatcaatttg ctgtatcgca taagatatcc
    52561 tacatatcag gagggtttaa tggatgctat cttattattg ataatatata tatccctacc
    52621 atcggttctt gctttgcttg tcggaatata aacaaagata taaataagta cactttatct
    52681 gataagacaa agtggccgac tacaccagag atgcctgcta ttttgggagg gataatgact
    52741 aatttaataa ttaaaatatt tctgggatgt tataatgaaa tcctaataga taacgcttac
    52801 gtttataata tgagaaatca tgctctaagt caagaaaaat atgttctgga aaacggagaa
    52861 tgtccaattt gtaaaaaaaa taataaagtg aaagataaca atattagagc gaaaacattt
    52921 attcgttcag tttgtttttg cttattatca ggaggagtag cttttttatc tgctattggg
    52981 cagttcactg ttatagaaac acaattaata gtattgttct tgggtattat ttttgctata
    53041 tattatgctt actacaataa aaatattcaa acatcattgg aaaatatagt atggcttttt
    53101 tcatcgtttg agattttatt tttgcttgtt aattttagaa catttattca gttaccagtg
    53161 gatattttta ttagtatgat aatattttta atgctgtgga tatttattat gttaggtata
    53221 gtgtgtctta gttattatat aactttatta tttagcaagg aggcttagta tgtttaaaaa
    53281 aataggtata atgagcattt gcatatatat aattatttta tactgcttga gaatgtatca
    53341 tattatcaat aatattgaaa caatcttgct aacggttata tgcttaatgt tattgttttt
    53401 tttaagacgt ttatttgata aagctaagta aatagatgtt aagtaaaaat gtagaatata
    53461 aaggaggggc aatgagtatg attgaagtta gccatttatc aaaaagtttt ggtgataaaa
    53521 tagctttaaa tgatataagt ttcactgtta aagaaggtca gatttttgga tttttaggac
    53581 catctggttc tggaaagacc acaacgatta atattctgac tgggcagctc cttgccgata
    53641 aaggacaatc tattattttg ggacaaaaat ctcaaaattt aacaagcggt gaattaaaga
    53701 gaattggatt ggttagcgat acaagtggat tttatgagaa aatgtctctg tataacaatc
    53761 ttctttttta tagtaaattt tataatatta gtaaattacg tgttgataat ttgttaaagc
    53821 gagtaggatt atatgatagt tgcaagatgg tagcaggaaa attatccact ggaatgaggc
    53881 aacgaatgct tttagcacga gctcttatca acaaacccgc tgtactcttt ctggatgaac
    53941 cgacctcagg tctagatccc acaacttctc gaacaattca tgagttaatt ttagaattga
    54001 aaacagcagg gacaacgatt tttctaacga ctcatgatat gaatgaagca actcttttat
    54061 gtgattatgt tgccttatta aataaaggga aattagttga gcaaggagct ccttctgaac
    54121 tcattcaaag atataataaa gataaaaaga ttaaggttac agattataat gggaatcaga
    54181 taacttttga ttttacatca ctagaacagg tatctcaggc tgatctggaa aatatttttt
    54241 caattcattc atgtgagcct actttagaag atatttttat cacattaaca ggaggaaagc
    54301 taaatgctta aacggtttct ggctttggta tggttgcgtt gtcaaattat cctttccaat
    54361 aagagtattt tattgcaagt tttagtgcct tttgctttca catattttta taaatatctt
    54421 atggaaacac aggggaaggt caacgatcaa caggcattag ttcttttgat gatgtgttta
    54481 cctttttctt tggctttggc tgttggaagt cctataacta ttatcttgtc tgaagaaaaa
    54541 gaaaagtaca atttacaaac tcttctgttg agtggtgtta aaggatccga atacatttta
    54601 tcaacgatgt ttcttccttt tttgctaact tttgtgatta tgggaactac tcctcttatt
    54661 ttaggagtta caattgtaca tacttttaat tatattacaa tcgttcttct aacctcttta
    54721 tccatcattt tattctattt attgataggt ttaaccgcga agagccaagt agtagctcag
    54781 gttatcagtc ttcctgctat gattttagtt gctttcttac cgatgctatc tggtttggat
    54841 aagacagttg cgaagataac agattatagt tttatgggac tgtttactaa gtttttcaca
    54901 aaatgggagg gattttcatg gaatgaaact ctaattccta atctaacact acttatttgg
    54961 attgttcttc tattaacttt aattacgata actattagga aaaagaaaat ttcttaattg
    55021 agttatttta atgattataa acacaagtgg gaaggaaaaa tgaactgatc tttttgacag
    55081 caattctaca gaatagtctt attgctatat tttgatttga gtgtacgaaa aaagaaaaat
    55141 aacaatagtg ctcatactaa ttgcagaagt tttgggtgat aagataactg ataaattgca
    55201 ataaaaaatg caacattttt aaatctcctc tataagtgct tcaaaacctg tcttgtaatc
    55261 caagtatttt tggggacggt gattaataag ctagcaaagc accattaagg attttttcgg
    55321 taattgttgc caaatcggtt taagaaaata ctcacgaaga agtccattcg cattctcatt
    55381 acttcccctt tgccaagatg aataggcatc cgcaaaataa aacagaattc ccatttgttc
    55441 aattaaaggg taacaagcaa actctttttc tctgtcctaa gtgaaagtct ttaactattc
    55501 ttttggaaag agtcttgtga ggtgttcaat agcagtcaac acatacgtga ccatgttttt
    55561 acttgacaag tgctagtaga aataatagaa tagtaaaaaa cctttaaagc agtccagaga
    55621 ggcagctaag gttagacggt gaaagggtgg agactaccca tttttcgtgg aaccttgctg
    55681 ttggcaggtt ccttttttcg tggcttctgt tggccagact ctctcactag taaaggtaaa
    55741 aggagaaacc tatgcgagaa catcgtccaa tcattgctct tgattttcct agttttgagg
    55801 cggtcaagga atttttagct cttttcccag cagaagaaag cctttatctc aaggtaggga
    55861 tggagcttta ttacgcagcg gggcctgaga ttgtgtccta cttaaaaggt ttgggtcata
    55921 gtgtcttttt ggatctcaaa cttcatgaca ttcctaatac agtcaagtca gcaatgaaga
    55981 tcctatctca gcttggtgtg gatatgacca atgttcatgc ggctggtggt gtagagatga
    56041 tgaaggctgc gcgtgaaggt cttggaagtc aagccaaatt gatcgctgta actcagctca
    56101 catcaacgtc agaagctcag atgcaggagt ttcaaaatat ccaaaccagt ctgcaagagt
    56161 ctgtgattca ctatgccaag aagacagctg aagctggctt ggatggtgtt gtttgctcgg
    56221 ctcaggaagt acaagtcatc aagcaggcta ccaatccaga ttttatctgt ctgacaccag
    56281 ggattcgtcc agctggtgtt gcagttggag atcaaaaacg agtcatgaca cctgctgatg
    56341 cctatcaaat cggcagtgac tatatcgtag tgggacgtcc cattacccaa gctgaggatc
    56401 ctgttgcagc ttatcatgcc atcaaggatg aatggacaca ggactggaat taaagaacta
    56461 gattagaaaa ataaaaggag aataccatga cacttgctaa agatatcgct agccacctct
    56521 tgaaaatcca agccgtttac ctcaaaccag aggaaccctt cacttgggca tctggtatca
    56581 agtcaccgat ttacactgat aatcgtgtga cactagccta tccagaaact cgtaccctaa
    56641 ttgaaaatgg ttttgtggaa gctatcaaag aagcctttcc tgaagtagaa gtgattgcag
    56701 gaactgcaac agcagggatt ccacacggag ccattattgc tgataagatg gacttgcctt
    56761 ttgcctacat ccgtagcaaa ccaaaagacc atggagctgg taatcaaatc gaaggtcgcg
    56821 tagctcaagg tcaaaaaatg gtagtggttg aagaccttat ttcaacgggt ggttcagttc
    56881 ttgaagctgt agcagcagcc aagcgagaag gagcagatgt gcttggagtt gtagcgattt
    56941 tcagctacca attgccaaaa gcagataaga actttgcaga tgctggtgtt aaacttgtga
    57001 cgctttcaaa ctatagcgag cttatccatc tagcccaaga agaaggttac atcacgccag
    57061 agggccttga tcttctaaaa cgctttaaag acgaccaaga aaattggcaa gaaggttagg
    57121 tcagtaagat aaagagagac gaggctaccg agcctctttt accattttat ttaaaatatg
    57181 acaatatttt aaataaaata attgacaacg ctttctttta ttgatataat gaaaatgtaa
    57241 tatgtatcaa attgatcaat caactatctt gtttatcact tcttaagagg acgatgtcat
    57301 gaaaagaaga aaaatatatt ccttttttgc gtagttacaa ttgcatctag tttgtttctc
    57361 cctacagttt tagctagaca gattggaaat tatgatttaa cgttgccgcg ttggggttcg
    57421 gatacaacta gtgagcttga gaaagaaaac gcctctgctg gaattaataa tagtgacagc
    57481 actggtggcg gtaaaaggtt aaatacctct attcgtagcg cgcctatagt gggtcagata
    57541 ttaccccggt atattcattg gggtctggct ctaggattgt catgtactat aatggaggtg
    57601 gtgacaatta tattggttct ggtactagat tagctatggc gccacaattt ggaaatcatg
    57661 taagaattca tacttcaggt tcttggagtc cagattctta ttaacttact tgtcagagta
    57721 agccttaaag atggttgatt gtgggtgtag catgaaaaaa gaatgctaca ccctattttt
    57781 attataagga ggagtaagga tggaattttt catttgtaat cttgtacgag tcgttcaatc
    57841 acctcgattt tatatgtctt tatttttgac ccttctttgc atgagtttag gaaatttcct
    57901 tgctttcaat ggtatttata aaattgaagg tttatcgatt ttttttgccg cttcttctat
    57961 tcgaggattt tcaccgatta gcctagtagc tgcacttatc tgtacactgc cctattctag
    58021 tcagataata gaggatgctg agagtcattt tctaacagca caattgtgcc gaatttctaa
    58081 aaagaggtat ctagctattg tgggtagtac tgcaattatt tcttcttttc tagtcttttt
    58141 tctcccctat ttattattat taggaattaa tcttttagtg actccttatc aggaaattta
    58201 tattggagat tatagtggtg ccttaaaaga attatttgat tctaatcagt tgctctatag
    58261 tcttgtgacg actctctggt atggagtttg gggcgctgtg ttctctattt ttggactagc
    58321 tagtgctttg ctagtgaaga aaaaaatagg agctattttc atcccagttg cctatatgat
    58381 ggttggtggt attttttggg ctattttagg gctatcttac ttagaacctg tgacaacatt
    58441 agctttggga tatcagaaag atatcagtct ttccttagtt agtgggcatc ttgcttttat
    58501 tttatttgtt agttgtttgg ttgtttatgg tacatttttt ctacattcag aggactacgt
    58561 ataatgaaac aatttgttca attttacaaa aaagattttt tatcagtatt ggtttatttt
    58621 atattactgc tatcctgtgt tttatctagt acagtatatt tattgcgctg tcgccaatat
    58681 tcaatccatc caaatgtatt agaatggatc ttagttttac ttcaagatat gacgactgga
    58741 gtatattgct ttccgttcac atatatattg ttcttttttt atttgatgaa taactatttt
    58801 aataggttgg agtgtcgcat tcgtctgaaa tcaattaagc actttaccag ttttagtttc
    58861 aaattagcag ctcttagtac ggggatttgg acggcgactt tatttttatt gatttttcta
    58921 attgcattta gtaatggttt tagcttctct ttggagataa aggaggttga ttttttaaga
    58981 gaattttatg gtataagtat tgcaaacaat gctagtttct ttataggatt ttttttctct
    59041 tatatagcat actatttctt tttatcctta cttactatta gcagtttttc ttggtttaaa
    59101 aaatcaaaca tgagcttagt atttctgttt acttttttat ttgtagaatc cttattctgg
    59161 atttatcagt tggacaatgg gataattgga ttattgccaa tttttcagta tatggtaaat
    59221 tccaatccgt atgcattgat ttattggctt acattactat ctatcataat tccattgact
    59281 gtattttctg ttcatagaaa ctggaggaga gtgtaaaagt tggaaatggg aaagttaagt
    59341 agtcacatgt ggaggttgaa tcagataatc tataccaagt acttttgggg ttatgttctt
    59401 ttttggatat tgatttgttt aggattatgg tattggttag aaggaaatga tagacttgtt
    59461 atagaaattt taaaagggcc taatctgagt caaaactctt ttttagtctt atctatatgg
    59521 ttgcttcatt ggtttattat tcatacattt tttctagcag ttgtatatcg tagaagagca
    59581 tccgatttct ttctggaagt gattcgattt tcttctatta agctctggat taggtatcag
    59641 atttggacct gttttcttta tggactcatt ttaatcatgg taaaagttct agtgattcaa
    59701 tttatgttac agttaccaaa ctgggatata ggagttttgt ttatagttga ttctttgaat
    59761 gcttgtgtgt tagtcttgtt ttgctttatg ttatacgcac taggagcgaa tgtacaaatg
    59821 aactttgctt gcgttagttt ctttttactc atgattgtgt ttggtggtct atttgtagga
    59881 aatcgaacta attatctatt ttatattttg aatcgaggga atggagatat aggacgagat
    59941 ttatttcttc agttgctatt tttagtcttt ctttttaaaa gtattttcta tttcactcgt
    60001 caaaagagga ggtttataga atgaatgaaa taatcatatt aaaaaatatt gagttgaaat
    60061 taaaaaaaac atgtgttttt caaaacctta attttagttg taaacagggg gaaattatag
    60121 gaattactgg tgcgaatggc tcagggaaaa gtgtattgtt taaattaata gctggtttat
    60181 atagtccgtc ttatggagaa gtgttaatca atggggaaaa tattgttcct gagagaaaaa
    60241 ttccagctaa tttgggagct ttgattgaag aacctggttt tataaattat tatagtggct
    60301 ttaagaattt acaatatttg gcaagcatac gaggagtagt tggtaatcag gaaatcaatg
    60361 atacactgaa aatagttggt ctatatgagc aaaaagacca gaaagttaaa acttattcgc
    60421 taggtatgag gaaaaagcta gggattgctc aagcaattat ggagaatccc tctattcttt
    60481 tactagatga acctatgaat gccttggata aatcaagtgt agaaaatatg agaacattgt
    60541 ttagaaagct ctctagtgaa aaagggacaa caattttgat tgctagtcat agtgaagagg
    60601 atattcgtat cttatgtgat aaagtatatg caatagaaga taaagtatgt acactgtgtt
    60661 cagattgaac atcttagata gactcaggat gttataggta aaatcttaaa aagggattgg
    60721 agcttaaaat ccagtccctt ttaagagtta atggccacct tcaacaacca ggtcatctgc
    60781 tttagcagcg tcaccgtagg ttgggtgaag tgttttttca taggccttgt ggaagaagtt
    60841 ttccttgcct aatttttcaa tatctttatt gatgaagtct agcaattctt ggttgccttt
    60901 ttgaactgct gccgcaatgg tatcgggatc accgagggaa gtaattccta cttcaaatcc
    60961 tttattttca agcgcccaag ctagaacttc cgtattgtca gttgaaaagg catctccacg
    61021 tccgtcaaga agagcttggt aagagtcact gtattggtcg tatttttgga gtttgatttc
    61081 tggatgattc ttttcaaaat aagtctcagc agtcgttcct tttgtgacaa ttaaggtttt
    61141 accttcaagt tgtttgacgt ctgtaatgag accagtctta ggtgatacga cacccagaga
    61201 aactttcata tatggaaggg caaaatcaac ttgtttctta cgttcgtcag ttactgtaaa
    61261 gttagcaaga gtaatatcta ccttgtttga aatcaagtat tccgcacggt tggcagcatc
    61321 gactgaaatg tatttaacct tgacaccaag gtctttagct agttggttcc ctagttcaat
    61381 atcgtagcct tggtaagaac catcattgtc aacgtagcca aacggttttt tatctccaaa
    61441 cacggcgatt cgcagttcac cgcctttttt tgatttcatc gatagtgcga gctttggcag
    61501 ttgtttttcc agaggatgaa ccagcgtttc cacctgagct acaagcagtg ataaagataa
    61561 gggcaaaggc aagtgctaaa acagttaaga gtggtttgaa tagtttcata agaatctcct
    61621 ttatagatat gagccaaatt ggctaaagtc aaagacgttt aaaaattcct gggctcgttt
    61681 ggtttgcgga ttggtaaaga aggcttgagc tgttccttct tcagcgattt tcccttggtc
    61741 gaggaagata atccggtcag caatggcttg ggcaaactgc atttcgtggg ttactaaaat
    61801 catggtacgg ccttcttggg ccaaatcatt gataagttcc agcacctcac gcaccatttc
    61861 tggatccagc gaagcagtca cctcgtcaaa aaggatgatt tctggatgca ttaggagggc
    61921 acggacaatt gcaacacgtt gcttctgtcc accagataat tgacgggcaa agctatgttg
    61981 tttatccagc aaaccgacac gatctagtaa ttgcaaagct tcttccgtta cttctttctt
    62041 gtcccttcct tgagttttga tagggcctag gatgaggttt tgtaagacat ccagatgggg
    62101 aaagagttca taactttgaa agaccatgcc aatcttttgg cgaactaggt gaaaattttt
    62161 tttattttca acgatagact gaccatccag aaaaatatct ccaccttgaa tactttctaa
    62221 gccgttgagg caacgaagga gggtactttt cccacaacca gatggcccta ggatgacaac
    62281 aacttcccct tttttgattt ctagagaaag tccttggagg atgggattgt ctccgaagga
    62341 tttttttagt tccttgattt ctaagatagt ttcagacatt tagtttctcc aatgtttttc
    62401 taagtgagtg gatagtttgg aaatagggta gcaaactgcg aaatataaga ctagaatggt
    62461 tccataaatc caaaatgaag cagttgggat ggtcaggcga ttgctatcga tgatttgttg
    62521 tccaactttg gtcacttcca caaccccaat caaaacaact aatgaagtgg ttttaatcat
    62581 ccgagtgaca agattgatag cctgcggtag cagtcttctc aagacttgtg ggatgatgat
    62641 gtggtagtaa agttgaacat tagtcaagcc gagtgcctgt ccactttcaa actgatgttt
    62701 agggagagaa gtgatagctc cacgtaccaa gtctcccatt tcagctgttc cccagagggt
    62761 aaaaacgata atagctgaag tctcacctga gatattgata ttaaagtttc gagccaagcc
    62821 aaagtaaacg atgaagagta gcaccagctg gggcatgata cggataaatt ccagatacaa
    62881 tcgtgttaaa aatcgtatga ttctagaatg ggaggtcatg atgattccca tgactgttcc
    62941 gaacatcatg gataagagga cagacaggat ggatatccca atcgtaacgc ccaatccctg
    63001 taagattctc aggagattat ttccttgaaa gagtacttgg attcccgaat cctgcatggc
    63061 ggagcctcct ttctatccag ctaaagacca gtgagatggg tagcagcatg atcagataag
    63121 caactaccaa catagctagc gcaatgtctg tctcatagta gagaccaatc aaatccttgg
    63181 cgacgtacat gaggtcggcc aaagccactg ctgagaaaac agaggtttcc ttgataagga
    63241 aaatgacatt ggcactaaag gaggggagtg ccaccgctgt tgcttgcgga agaaccacat
    63301 agtaaaagac ctgtagaggt gtcagaccaa tagcgaggcc aatctcctgc tgggtttgac
    63361 tgatggcttc cagcccactt cggaaagatt ctgccatata ggagtctcct aaaaagacaa
    63421 gcccaagcgt tgcacagact tctgaagata ggacaatccc gattcgggga agaccgaagt
    63481 agagaaagaa gagttgaatc aaaaggggcg tattacgtga caattcaatg taggctgtcg
    63541 ctacttgcga caaaacaagg attcgataat gtcggatgat actaacgatt aaaccgagca
    63601 gaaaggatcc caaaattccc caaactgcaa tatgcaaggt cagaaagaat gccttttgat
    63661 atagtggtag atattgttca acaatggatc aatccaaaaa tagaacctcc catctagaaa
    63721 taatacagtt attgtagcac ttaaaatctt ctttggataa tatctatttt ttattgccgt
    63781 tataaggatt tttatcatag acataaaatt tctgaaattt ccaaacaaaa tattttaaaa
    63841 gttttgaaaa agagttaaga tatttttgta atacacaaag taaacgctta cttattaagg
    63901 aggacatttt atgtcataca aaacaagcaa tgcagaaggt catgtagatt tcatcaatac
    63961 ctatgatttg gagccaatgg cgcaacaagt tattcctaaa gcagcatttg gctatatcgc
    64021 tagtggggcg ggagatactt tcacttcttt ccagtgattt tagcgtcagg ttctttttag
    64081 tttttaaaga ttatccgtga atttcttgct tatttatgat aaaatgggag tatcgcaaaa
    64141 aatgactcat cgtattcaat tttgagtaaa actaggagga tcccatgtct acagaacata
    64201 tggaagaact aaatgaccag cagatcgttc gccgtgaaaa aatggctgcg ctccgcgaac
    64261 aaggaatcga tcctttcgga aaacgttttg aacgtactgc aaattcacaa gaattaaaag
    64321 ataaatatac caacctcgat aaagaacaat tacacgataa aaacgaaaca gctactatcg
    64381 caggacgctt ggtaaccaaa cgtggtaaag gaaaagttgg ttttgcccac cttcaagacc
    64441 gcgaaggcca gattcagatc tacgttcgta aggatgctgt cggtgaagaa aactacgaaa
    64501 tcttcaaaaa agcagacctt ggtgacttcc ttggtgtcga aggtgaagtg atgcgtacgg
    64561 atatgggaga actctctatc aaggcaaccc acatcacaca cttgtctaag gctcttcgtc
    64621 ctcttcctga gaaattccat ggtttgacag acgttgaaac aatttaccgt aaacgttacc
    64681 ttgacttgat ttctaaccgt gaaagctttg aacgctttgt cactcgttca aaaatcatct
    64741 ctgaaatccg tcgttacctt gaccaaaaag gattccttga agtggaaaca cctgttcttc
    64801 ataatgaagc cggtggtgct gctgcccgtc catttatcac ccaccacaat gcccaaaaca
    64861 ttgacatggt gcttcgtatc gcgactgagc ttcacttaaa acgccttatc gtgggtggta
    64921 tggaacgtgt ctatgaaatt ggccgtatct tccgtaacga aggaatggac gctactcata
    64981 accctgagtt tacttctatc gaagtttacc aagcttatgc agacttccaa gacatcatgg
    65041 acttgacgga aggcattatc caacacgctg ctaaatcagt taagggcgat ggcccagtca
    65101 actaccaagg tactgaaatc aagattaacg aaccatttaa gcgtgttcat atggtggatg
    65161 ctatcagaga aattactggt gtcgatttct ggcaagacat gactttagaa gaagctaaag
    65221 ctatcgctgc tgagaagaaa gttccagttg agaaacacta cactgaggtt ggtcacatca
    65281 tcaatgcctt ctttgaagag tttgttgaag aaactttaat ccaaccaacc tttgtctatg
    65341 gacatccagt agctgtatct ccactcgcta agaaaaatcc tgaagatcaa cgctttactg
    65401 accgtttcga gctctttatc atgactaagg agtacggtaa tgcctttact gagttgaacg
    65461 acccaatcga ccaacttagc cgttttgaag cccaagctaa agctaaagaa cttggtgatg
    65521 atgaagcgac aggcatcgac tatgactaca tcgaggctct tgaatacggt atgccaccaa
    65581 caggtggttt gggaatcggt atcgaccgtc tctgcatgct cctcactgat acaacaacta
    65641 tccgtgatgt attgctcttc ccaacaatga aataaattct tatcctctgg ctcttaccag
    65701 aggatttttt gattcaaaaa gagactgaat ttaaggagaa aatgaagtgt agtatattga
    65761 agttgaaata gtacactttg atttctaaga cattgttaga aattggttta aattccctaa
    65821 tcaatttgtg catgttttat ttcattttac gatagtacgc tgaaactgtt caaaaagtac
    65881 tagaaattga cttggattcc ccaattgatt tgttcagatt cactataaat aaaaaattaa
    65941 taagtgggat aggaagttag cgtcaactag gatagtatct tgcttaaaca gtatatatgg
    66001 gactgatata agtccatagg tcctattaga ggatgttctg gtgtcttatt cacttgcttt
    66061 tttatagtat tagtagatag aatcagcaaa taaaaaagta gttcaaatgc ctggcagcaa
    66121 aaaatctcaa cgattcactt aatatagact aaagtttaga gtttaaggaa agtagggcta
    66181 gtatattgta tgaaaaaata agatggtttt taagcaaaac tcttgaaaat gattgaaaaa
    66241 agagttatta tagttgtgta gtaaaaagca aacgcttact taatcaagga gggcatttta
    66301 tgtcatacaa aacaagcaat gcagaaggtc atgtagactt catcaatacc tatgatttgg
    66361 agccaatggc gcaacaagtt attcctaaag cagcatttgg ctatatcgct agtggggcgg
    66421 aagatacttt cactttaaga gagaatatcc gcgcctttaa ccacaaactc atcgttcctc
    66481 atacactttg cgatgttgaa aatccaagta cagagattga atttgcaggt gaaaaactat
    66541 cttcaccaat cattatggcg cctgttgcgg ctcataaatt ggcaaatgaa cagggggaag
    66601 tggcgactgc gcgtggtgtg catgagtttg gttctcttta tacaaccagt tcttactcta
    66661 ctgttgacct tccagagatt tctgaagccc ttcaagggac acctcattgg tttcaatttt
    66721 actttagtaa ggatgacggt atcaaccgcc acatcatgga ccgtgtgaag gctgaaggtt
    66781 ataaagcgat tgtcttgacg gcagatgcta ctgtaggggg gaatcgtgaa gtggataagc
    66841 gtaatggttt tgtcttccca gttggcatgc cgattgttga agaatacctg ccagaaggtg
    66901 ctggtaaatc aatggacttt gtttacaaat cagctaaaca acgcttgtct ccacgcgatg
    66961 tagaatttat cgctgaatac tctggtcttc ctgtgtatgt caagggacca caatgccgtg
    67021 aggacgttga acgttcgctt gctgcaggag cttctggtat ctgggtaacc aaccacggtg
    67081 gtcgtcaaat cgacggtgga ccagctgcct ttgactcgct tcaagaagtg gcagaagcag
    67141 ttgatagacg tgtgccgatt gtctttgact ctggtgttcg tcgtggtcaa cacgtcttta
    67201 aagccttggc atcaggagca gacttggttg ctattggacg ccctgtcatc tatggtttgg
    67261 ctctcggtgg tagtgtcggt gtgcgtcaag tctttgaaca cttgaatgcg gaattgaaga
    67321 cagttatgca attgtctgga gctcagacca ttgaagatgt caaacacttc aagctccgtc
    67381 acaatccata caacccaacc ttcccagttg accctcgtga cttaaaattg tattgataaa
    67441 acagattgcc tccactgaat gtggaggttt ttcttcgtgt attggaagaa taaattgcta
    67501 tcgaaaacta tagtaaaatg aaataagaat aggacaaatc aatcaggaca gtcaaatcga
    67561 tttctaacaa tgttttagaa gtagaggtgt actattctag tttcaatcta ctatataaag
    67621 atatttttcg gtcaaatatc ttgctagggc tttcattttt tgctatactg gttcagtaat
    67681 taaataatag agacatttgg ggtgctttag gctgagataa tacccattga acctgataca
    67741 gttaagactg gcgaagggaa atgtgaaacg ttttttcgta tggcgaaatg aacggtctaa
    67801 tcttgtaagt caactctaat tcttgattgt aattggagtt ttttgtttat ataaactgga
    67861 taggcttgtt tagttagctc tctgcaaatg ctctcgatgt gctttaaaag gatcaagtgg
    67921 aattacgatt ttgcttgata tttcttggtg ttttattaat tactaacaag taaagagagg
    67981 agaagtaaat atggaaacac aagactatgc atttcagcca gttttgactg ttggagaatt
    68041 attaaaaagc agtcagaagg attggcaggc tgcaatcaat catcgttttg ttaaggaact
    68101 ttttgcgggg acaattgaga ataaggtctt aaaggactat ctgattcaag attatcactt
    68161 ctttgatgcc ttcttatcca tgctgggtgc ctgcgtagct cacgcagata aacttgaatc
    68221 caagcttcgt tttgccaagc aactaggctt tcttgaagca gatgaagatg gttatttcca
    68281 aaaggctttt aaagagttaa aagtagcaga gaatgactat ctagaagtga ctttgcaccc
    68341 tgtaacaaaa gcctttcagg atctaatgta ttgggcagtg gcttcatcag actatgccca
    68401 tcttttggtt atgctggtca ttgcagaagg tctctattta gactggggtt ctaaagattt
    68461 ggctctacct gaagtctata ttcattcgga atggatcaat ctccacagag gtcctttctt
    68521 tgcagagtgg gttcaatttc tggttgatga actcaatcgt gtcggtaaaa atcgagaaga
    68581 tttgacagaa cttcagcaac gctggaatca agcagtcgct ttagaattag ctttttttga
    68641 tattggttac gatgtctaga gaaggctcat gatatttaca aatttgatga ggtaagactc
    68701 ttcgaaaatc tcttcaaacc acgtcagttc tatccacaac ctcaaaacag tgttttgagc
    68761 tgacttcgtc agtcttatct acaggctcaa agcagtgttt tgagcaacct gcggttagcc
    68821 tcctagtttg ctctttgatt ttcattgagt ataaatcatt caatgtaaat gaaaaaaatt
    68881 ctcaactaaa gataaatcga aattagtaga tcgtataaag tgaaaaggaa ggatttcaat
    68941 atgacaagtt taaaattatt aaaagaaaaa gcaccattgg tcatttgtat aaccaatgat
    69001 gtagtaaaaa atttcacagc aaatggatta gtagcactgg gcgcctcacc agccatgagt
    69061 gagtttccag cagatttaga ggatttgtta aagtatgctg gtggtttatt aataaacata
    69121 ggaacattga cagatgaaaa ttggaaatta taccaagctg ctctgaaaat tgcagagaaa
    69181 tataatgtcc cagtagtttt agatcctgta gcctgtggag caggagaata tagaaaaaaa
    69241 gtagcagatg atttaatcaa caattacaaa ctagctgcga ttagggggaa tgctggagag
    69301 attgcctctt tagtaggaat agatgtggca tctaaaggag tagatagtgc gggcgtagat
    69361 aatattgacg aaattgctct agcagcaaat gagaagttca atattccaat agtagtaaca
    69421 ggtgaagtgg atgccattgc tgttaatgga gaagtggtaa cgattcataa tggtagtgct
    69481 atgatgccga aagtcattgg gacaggatgc ttattaggag ctgtagtagc aagttttatc
    69541 ggactggaaa aaggtcaaga attaaaatca ttagaaacag caatgttagt ttacaatatc
    69601 gctggagaaa tggcagaaaa acgtccaaat ggacatcttc ctgggacatt taaagttgaa
    69661 tttataaatg ccttatacga gattacagat gaagatgtaa aggaattcaa aagagtgaag
    69721 taagatgttt cataaagaat tactaaaact atattttatt tgtggaacga ctacttgcca
    69781 aggaaaaaat ctatatacag tcgttgagga agccttaaaa ggtggtataa ccttatttca
    69841 atttcgagaa aaaggtgagg gtgctttaga aggcttagaa aaacttgagc tagctatcca
    69901 aattaaagaa ctttgtaaaa aatacaatgt tccatttatc gttaatgacg atatagattt
    69961 agcaatggaa attgatgccg atggcgtaca tgtaggtcaa gatgatattg gtgttgatga
    70021 aattagaaaa ttgatgccag ataaaataat tggtctttct ataagaaacg aagaagaatt
    70081 tcaacaatca aaagttgaat atgtagatta tgtaggtgtt gggcctgtat ttgataccca
    70141 gtcaaaagat gatgctggtg gtgctatagg ttatgaaggt cttgaattga tgagaaaact
    70201 attgccacaa atgcctttag ttgcaattgg tgggatacag acgaaacata ttaaagacat
    70261 tataaagacc aatatggatg gcgtttcaat catttcggca atatcgtatg caaaaaatat
    70321 agaaaaaact gttcgggaaa tgagtgaaca atagatatct atccttggat tctaagtaag
    70381 taggattttc cttttttaaa aagctatgtc cagattcagc ttgaatggct aattcatcaa
    70441 acaggtcatt tgttttttgc aaaagaaaga tctgctgtct ttgtgagtgc aaggctgtat
    70501 ttccagttca atttcttgaa ctagtataaa atgtgtgtta taataatcac ataattaaat
    70561 aataaagaca tttggggtgc tttaggctga gatgataccc attgaacctg atacagttaa
    70621 gactggcgaa gggaaatgtg aaatgttttt ttcgtatgtc gaaaagaact gtctaatctt
    70681 gtaagctgaa ctctaattcg tatctgtaat tagagttttt tcttttacga aactggatga
    70741 agatgatata gtagattgaa ataagatgcg aacaaatcaa ttagaaaatt caaattaatt
    70801 tctagaaata ttttagtgtt cttgtgtact gttctaaatt cagtctgcta tacaaagtat
    70861 ttaggtcggt cttcttgagt gccccacttt tctttaaaaa aaggagtttt tttatgttga
    70921 aaaaatggca gttaaaagat gttatcttgc ttgctttctt gtctatcttt tttggtgggg
    70981 ttttcgttgg ttcaggatat gtgtataata ttctcagtct actcttaaca cctcttggtt
    71041 tgcaggcctt tgccaatgaa atcctcttcg gtctctggtg tatggctgcg cccattgctg
    71101 ccatctttgt tccgagagtc ggaagtgcaa cgattggaga agtgctagct gcgcttgctg
    71161 aagtccttta tggtagccaa tttggtctag gagctctttt gtctggcttg gttcaaggtt
    71221 tgggaagtga atttggtttt atcgtaacta agaatcgcta tgaaagttgg ctctctctaa
    71281 ctgctaatag tattgggatt acgcttgtta gctttgtcta tgaatacatt aagttaggtt
    71341 actacgcctt ttcccttccg tttgtccttt ccttgcttgt ggtacgtttt atttctgttt
    71401 atttcttctg taccatcttg gttcgtgcca ttgtcaaact ctatcatcag tttgcaactg
    71461 gaggaaaagc atagatgggt ctggaactac gagcgattca gtccccaatt ttctctgagc
    71521 cgtttgattt tacttttcat gcgcaagcct ttaccttgtt agttgggagc agtggttcag
    71581 gaaaatccag cctctttcaa atgattgccc aagtcagttc tcttccctat agcggtcaag
    71641 tcctgataga tgggagtgag gtcagtcagc tttctatcgt cgaacgtgtc cagaaggttg
    71701 gcattctctt tcaaaatccc aatcatcaat ttaccatgga gaacttgttt gaggagctga
    71761 ttttcacctt ggagaatatc ggctatcacc ttcaggaaat tgattctaaa atagcagagg
    71821 ttgtccagca atgtcgttgc gaggcaatct tacaccgtcc cattcatcac ctatcaggtg
    71881 gggaaaagca aaaagcagcg ctggctgtcc tctttgccat gaatcctagg gtctatctct
    71941 tggatgagcc cttcgcttcc attgaccgca agagcagaat cgagatattg gagattctaa
    72001 aagagttggc tcttgatggg aagacagtta ttttgtgcga ccatgattta tctgactata
    72061 aagcctatat cgaccatatg gttgagctaa gagacggaaa actaagggaa gtgtttcaaa
    72121 tcccttccta tgagatgaca caggttgctt caaaggaagt tgcttctagc ccggaattat
    72181 tccatatgaa ccgtgtgact ggtgagcttg gtaatcgccc cctcttttca attgctgatt
    72241 tcacattcta tcaagggatt tcctgtatcc tgggtgacaa tggtgtcggg aaatcaaccc
    72301 tctttcggtc tattcttcaa tttcaaaagt ataaggggcg cattgcatgg aaggggacag
    72361 tcctgaaaaa gaaaaagagt ttgtaccgtg atctgacggg tattgttcag gaagctgaga
    72421 agcagtttat ccgagtcagt ctgcgagagg agcttcaatt agatggacct gattctgaaa
    72481 gaaatcagcg gatttttcaa gctttacgat attttgattt ggagcaggca gtcgataaga
    72541 gtccctatca attaagtggt ggtcagcaaa aaattcttca gctcttgacc atcttgacca
    72601 gtaaggcttc cgtgatcttg ctagatgaac cttttgcagg tttggatgat agagcctgcc
    72661 attatttttg caagtggatt gtggaggaga ggaatcaagg aagaagtttt ctgctcatta
    72721 gtcatcgttt agaccctttg atttctgtgg ttgattattg gattgagatg actagtcagg
    72781 gtcttcggca tgtgaaagaa gtgaccatta ccaaaccact tacatctcag agtagcaata
    72841 cccaagggga ggtgagatag tatggtcaaa gtagcaaccc agacaccgat tatcagtctc
    72901 ttcttgctga ttttatcctt ggaaacatct ttcattcctt cgattgctct gaatctttcg
    72961 gtagtcgcat tttgtattct ctttatgctc tattaccgtc gatttaaaat gttagcttgg
    73021 atgatcatac ttgccatttt accatctttt gccaactact gggcagttca gttacacgga
    73081 gatgcttcac aggcagtcat gcttggaacg agggcctttg tgacagtttg tatcggcctt
    73141 gtctttgttt cctctatttc actaaaagag cttctcttgt acttggctca aaaggggcta
    73201 tcacgctctt ggtcctatgc cttgattgtg gtattcaatt cctttcctct cattcagcaa
    73261 gaaatcaagt ccctcaaaga agcttgccta ttacgtggtc aagaactaca tttttggtcg
    73321 cccttgattt acagtaaggt tctgatgaca gtctttaggt ggcgccatct ttacctgaga
    73381 gctctatctg ctcacggata tgacgaacat gcacagttga agaatagcta tcggactttt
    73441 tatattccta aaaaaacaaa attaatctac ctgcttttct ttttattgct tcaaaccagt
    73501 ctatttttat aaaggagtta ttatggaatt tacagatatt gcgatggaat tatccaagaa
    73561 agcttggcag gcttcctttc atcatccctt tattttacaa ttacaagagg ggaatttaga
    73621 acctgccatt ttccgctatt acctgattca ggatgcctac tatctgaagg ctttctcaga
    73681 aatctatcat cttttggctg ataagacttc aaaccaagag atgaaaagac tcttgaaaca
    73741 aaatgctcag ggtttagtgg agggtgagtt atttattcgc caacaatttt tcaaggaatt
    73801 ggaaatcagc gaccaggaaa tggagcaaca tccaatcgct ccaacctgtt atcattacat
    73861 ttctcatatt tataggcaat ttgcagaacc gaacttagcc atcgcttttg caagcttgct
    73921 tccttgtcct tggttatacc atgatatagg caaatcactt aatcttaaac catcaccaaa
    73981 tcctctctat caacaatgga ttgaaactta tattacggat gagttagagc aacagatcag
    74041 agaggaggga gcactggtca atcagctcta tcgagaaagt gatgagacag ataagcaaaa
    74101 aatgctagat gccttccaca tcagtgttca tatggaagcc aagttttggg agatggctta
    74161 ccaacaccag acatggaaga gcgatttaca gtctttagaa aaaggagaag aatagaaaca
    74221 tgagaaagca ccaactacaa gttcacaaat tgaccatttt atctatgatg attgcccttg
    74281 atgtagtcct tacacctatc tttcggattg agggaatggc accgatgtcc agtgtagtca
    74341 atattctagc gggaatcatg atgggacctg tttatgcctt ggctatggct acagtgacag
    74401 cctttatccg tatgacgact caagggattc cgcctttagc tctcacagga gcgacttttg
    74461 gagcccttct agcaggtctc ttttataagt acggtcgaaa attttacttt tctgccttgg
    74521 gagaaattgt gggaacaggt attattggtt ctattgtttc ctatcctgtt atggtactct
    74581 ttacaggatc agctactaag cttagctggt ttatctacac gcctcgattt ttcggagcaa
    74641 ccttgattgg tacagcgatt tcctttattg cctttcgatt tttaatcaag caggaattct
    74701 ttaaaaaagt gcagggatat ttctttagtg aaaggataga ctgatgcagg aatttacaaa
    74761 tccctttcct ataggctcta gttccctcat tcactgtatg accaatgaga tttcttgtga
    74821 gatgctggca aatgggattt tggctctggg atgcaaacct gtcatggcag atgatccccg
    74881 tgaggttctt gattttacta agcaaagtca ggctctcttc atcaatttgg ggcatttgtc
    74941 agctgagaag gagaaagcaa tccgtatagc agcttcttat gcagctcaag tttgtctccc
    75001 aatggtagta gatgcggttg gcgtaacagc ttcatccatt cgtaagagct tagtcagaga
    75061 ccttttagac tatagaccta cggtccttaa aggaaacatg tcagaaattc gaagtcttgt
    75121 tggattaaag caccacggcg ttggggtcga tgcgagtgct aaagatcaag aaacggagga
    75181 tttgcttcaa gtcttgaaag actggtgtca gacctatcat ggtatgtctt tcttagtcac
    75241 aggtcccaag gacctcgtcg tttcgaaaaa tcaggtcgct gtactgggaa atggctgtgc
    75301 agaattagac tggataacag ggacaggaga tttggttgga gccttaacag ccgtttttct
    75361 cagccaagga aagactggtt ttgaagcttc ttgcttagca gtctcttatc tcaatatcgc
    75421 tgctgagaaa atagttgttc aaggaatggg attggaagaa tttcgttacc aagtactcaa
    75481 tcagctttcg ctcctaagaa gagatgaaaa ttggctagat accatcaaag gagaggttta
    75541 tgaatagaga agcacttaga ctatatctgg taaccaatcg ctatcaagat tccgtggaaa
    75601 gctttcttgc aaaagttgag acggcctgcc gttcaggggt taccatagtc caattgcgag
    75661 aaaaaaatct cacaaccaat caatattatc aactggcaaa acaagtcaag gaaataacag
    75721 atgcttatca ggtacccttg ataatcgatg atcggttgga tgtttgtctt gcggttgatg
    75781 ctgctggtct gcatattgga gatgacgaac tcccagtttc ggttgcccga caagtcttgg
    75841 gtcctgaaaa aatcctcggt gtcaccgcta aaacggttaa aagagctctg gaagcggaga
    75901 aatcaggtgc agattacttg gggacaggag ccatttttcc gacaaccacc aaggaaaatg
    75961 cacccatcac cctgatttca accttgaaaa caatttgcca aacggttgcc attccaatag
    76021 ttgctattgg tggcttgact tcggagaata ttgatcagct tatgggcact ggcatagctg
    76081 gtgtagctgt tgtacgtgat ttgatgcaag cagaagatat tgaggcaaaa acgcaagcct
    76141 ttttaacaaa gttgcatgac attctttcct aattaatact caatgaaaat caaagagtaa
    76201 actagaaagc tagtcgcagg ttgctcaaag tactgccttg aggttttaga taagactgac
    76261 gaagtcagct caaaacagtg ttttgaagtt gcagatggaa gctgacgtag tttgaagaga
    76321 ttttcgaaga gtataaaaac tctctaattc ccttaaagtg ggaactagag agtttttttt
    76381 cttaatcttt aaaagttgta tggttgactg gaccagaacc atgaccgagt tgaggggcat
    76441 cttgaatagc ttttgtgata aaggccttgg ccttatcaac tgcctggtaa agactcttgc
    76501 ccttggctag ttcagcagta atcactgcag caaaggtaca tccagtacca tgggtgtgac
    76561 aggtttgaat tcgtgggctt tcccagacaa attgttcatt cttggtaaag aggaaatctt
    76621 tagcaccacc tttgagatgt ccgcctttga taaccacaga ctgaggacca aattctttta
    76681 aaatcaggcg accagcacgc tgcatgtctt cggggtcatg gattgaaaaa ccaacaatct
    76741 cttctgcttc aggaagattt ggcgtaataa tagttgctag aggtagtaag tttgttttga
    76801 gatagtctct agcacttgag tcaatcaagg catctccact tgtagcaacc ataacaggat
    76861 caaggacata gggacaatcc agttttttaa gatagggttg gatgatttcc atgatttcag
    76921 tagtagccaa cattccagtt tttacagcct gaggtggaat atcagaaaag acactctcca
    76981 attgggcttt caacatttga ggagaaacgt gctcgattag ctgaacacct ctggtatttt
    77041 gagcgacaag actggttaca acagccattc catagacatc tctcgcttgg aatgacttta
    77101 aatctgccat aatgccagca ccaccactag ggtcagtccc tgcaatggtc aaagcaacgg
    77161 gtaaataagt catctaaaac ctcccaacca actgaagttt gtattcttaa gaacaagcta
    77221 gtctgtttta gaaaggcaat agaagactgc tagtccccat tatcatttcc acttccatca
    77281 gctagcatta cctagattga gtcagaggga tctaacagtc gttaatctca gctttacgca
    77341 cccctagtgg ttgttttctt ttttctttag tatagcatat ttttattgtt tatatagtaa
    77401 tatttgactg caaatcgttt ttcaaatgat taaaattcta tttttcgaag aaaatattat
    77461 ttctataatt gacaaatgta gattttggga gtatactgtt gagtgtaatt gacaaatgta
    77521 gattttggag gtatggtaat gcagatttca gatgcagaat ggcaggtcat gaagattatt
    77581 tggatgcagg gggagcagac cagtacagat ttgattaggg ttttggcaga gcggtttgac
    77641 tggtccaagt ccacggttca gacacttttg gctcgtctag ttgagaaaga gtgtttgact
    77701 cggaaaaaag aaggcaagtc ctttgtttat tcagcgcttt taactctaga ccaaagtcgg
    77761 gatttacttg tccaagatat caaagacaag gtttgttccc gtaggattag gaatttgttg
    77821 gctgacttga ttgtagaatg tgaatttact cagactgact tggaagactt ggaagctgtg
    77881 atttcagaga agaaatcaag tgctgtaaca gaagtaagat gtaattgtat gtaaaggaga
    77941 cgtcatgtta aatagtattg taaccattat ttgtattgcc cttatcgcgt ttatcttgtt
    78001 ttggtttttc aaaaagcctg aaaaatctgg acaaaaagcc cagcaaaaaa acggatacca
    78061 agagattcga gtggaagtca tgggaggcta tactcctgag ttgattgtcc tcaagaaatc
    78121 agtgccagcc cgcattgtct ttgaccgcaa ggatccttca ccatgtctgg atcaaattgt
    78181 ttttccagat tttggtgtac atgcgaacct gccaatgggg gaagagtatg tagtggaaat
    78241 cacgcctgaa caggctggag agtttagctt tgcttgtggt atgaacatga tgcacggcaa
    78301 gatgattgta gagtaggtgg agactatgac agaaattgtg aaagcaagct tagaaaatgg
    78361 cattcaaaaa atccgtatcc aagctgaaaa aggctatcat ccagcccata tccagcttca
    78421 aaagggaatt ccagctgaga ttacctttca tcgtgctact ccttcaaact gttataagga
    78481 aattctgttt gaagaagaag gtatcttgga accaatcggc gtagatgagg agaaagtcat
    78541 tcgttttaca cctcaagaat tagggcgaca tgaattttct tgtggcatga agatgcaaaa
    78601 gggaagctat acagtcgttg agaagactcg aaaatctcta tctctcctgc aacgtttttg
    78661 gattactagt atctgtactg tgcctcttgt gattctcatg attgggatgt tggcaggtag
    78721 cattagtcat caagtcatgc attggggaac ctttctagca acaacgccta ttatgttagt
    78781 tgcaggtaag ccatatatcc agagtgcttg ggccagtttt aaaaagcaca atgccaacat
    78841 ggataccttg gttgcgctgg gaactctagt ggcttatttc tatagcctag ttgctctctt
    78901 tgctggtctc cctgtttact tcgaaagtgc tggatttatc ctctttttcg ttcttttggg
    78961 agcagttttt gaggaaaaaa tgagaaaaaa tacgtcccaa gctgtggaga aattactgga
    79021 cttgcaagct aaaaccgcag aagtcttgag tgatgatagt tatgtccaag ttcctttgga
    79081 acaagtcaag gtaggcgacc tgattcgagt gcgtcccggt gaaaagattg ctgttgatgg
    79141 tgtcgtagta gaaggtgtct ctagtattga cgaatccatg gtgacaggtg agagtctgcc
    79201 tgtggacaag acagttggag atactgtcat tggctcaacc atcaatcata gtggaacgct
    79261 tgtctttaga gcagaaaaag ttggctcaga gactgttttg gctcagattg tggattttgt
    79321 gaagaaagct cagataagtc gtgcgccgat tcaggacttg acggataaga tttcagggat
    79381 ttttgtccca gtagttgtca ttttaggaat catgaccttt tgggtttggt tcgtcttgct
    79441 cagggatagt gtggttgtgc ttggagctag ctttgtgtcc tctcttctct acggagtggc
    79501 ggttttgatt atcgcctgtc cttgtgcctt gggacttgca acaccgacag cccttatggt
    79561 ggggacagga cgtagtgcca agatgggggt tctcctcaaa aatggaactg tcttacagga
    79621 aatccagaaa gttcaaaccc ttgtctttga taagaccggg actttgacgg aagggaaacc
    79681 tgtggtaaca gatgtcatcg gcgacgaagt agaagtgttt ggattggcag cctccttgga
    79741 agatgcttct caacacccac tggctgaggc tatcgttaag cgagcgagtg aagctggact
    79801 tgagtttcaa actgttgaaa attttcaggc cttgcacggg aaaggtgttt cagggcgaat
    79861 caatggaaaa caagttttac ttggaaatgc taaaatgctg gatggcatgg atatttctaa
    79921 tacttatcaa gataaactag aagaactaga aaaagaagct aagacagttg tgttcttagc
    79981 tgttgacaat gaaatcaaag gcttgcttgc tttgcaagat attcctaaga aaaatgctaa
    80041 gctagccatc agtcagctaa aaaaacgtgg tctcgggaca gtcatgctga caggagacaa
    80101 tgctggtgtg gcgcgtgcta ttgcagatca aatcggaatt gaagaggtca ttgcaggcgt
    80161 cttgccagaa gaaaaagccc atgaaatcca taaactgcaa cagtcaggta aagtagcctt
    80221 tgttggtgat gggatcaatg acgctcctgc ccttagtgta gcagatgtgg ggattgctat
    80281 gggagctgga acagatatcg ccatcgagtc agcagatttg gtgttgacaa ccaataatct
    80341 tttaggagtg gtgcgtgcct tcgacatgag taagaaaacc tttcatcgta ttctgctcaa
    80401 tcttttctgg gcttttatct acaatgttgt cggaattccg attgcagcag gagtcttttc
    80461 aggtgttgga ctggctctca acccagaatt ggcaggtcta gccatggcct ttagttctgt
    80521 atctgttctg accagttccc ttctgttaaa ttttagtaaa atagactaaa agtaatgact
    80581 agattttttt gttataaaac agaaatgacg acactttcaa aactgtatta gaatagagaa
    80641 tagagagttt tgagcagatt tttagaaaag tcagcataaa tatgatacag tggaatagta
    80701 aaaatttgga gaacgtttcc aattctatgt aatcgtattc tccaagtcta aaaaaattga
    80761 aggagagtta tcattatgac tcaagggaaa attactgcat ctgcagcaat gcttaacgta
    80821 ttgaaaacat ggggcgtaga tacaatctac ggtatcccat caggaacact cagctcattg
    80881 atggacgctt tggctgaaga caaagatatc cgcttcttac aagttcgcca cgaagagaca
    80941 ggtgctcttg cagcggttat gcaagctaaa ttcggcggct caatcggggt tgcagttggt
    81001 tcaggtggtc caggtgcgac tcacttgatt aacggtgttt acgatgcagc tatggataac
    81061 actccattcc tagcaatcct tggatcacgt ccagttaacg aattgaacat ggatgctttc
    81121 caagagctta accaaaaccc aatgtacaac ggtatcgctg tttacaacaa acgtgtagct
    81181 tacgctgagc aattgccaaa agtaattgac gaagcctgcc gtgctgcagt ttctaaaaaa
    81241 ggtccagctg ttgttgaaat tccagtaaac ttcggtttcc aagaaatcga cgaaaactca
    81301 tactacggtt caggttcata cgaacgctca ttcatcgctc ctgctttgaa cgaagttgaa
    81361 atcgacaaag ctgttgaaat cttgaacaat gctgaacgcc cagttatcta tgctggattt
    81421 ggtggtgtta aagctggtga agtgattact gaattgtcac gtaaaatcaa agcaccaatc
    81481 atcacaactg gtaaaaactt tgaagctttc gaatggaact atgaaggttt gacaggttct
    81541 gcttatcgtg ttggttggaa accagccaac gaagtggtct ttgaagcaga cacagttctt
    81601 ttccttggtt caaacttccc atttgctgaa gtttacgaag cattcaagaa cactgaaaaa
    81661 ttcatccaag ttgatatcga cccttacaaa cttggtaaac gtcatgccct tgacgcttca
    81721 atccttggtg atgctggtca agcagctaaa gctatccttg acaaagtaaa cccagttgaa
    81781 tcaactccat ggtggcgtgc aaacgttaag aacaaccaaa actggcgtga ttacatgaac
    81841 aaactcgaag gtaaaactga gggtgaattg caattgtatc aagtttacaa tgcaatcaac
    81901 aaacatgctg atcaagacgc tatctactca atcgacgtag gtaacactac tcaaacatct
    81961 actcgtcacc ttcacatgac acctaagaac atgtggcgta catctccact ctttgcgaca
    82021 atgggtattg cccttcctgg tggtatcgct gctaagaaag acaatccaga tcgccaagta
    82081 tggaacatca tgggtgacgg agcattcaac atgtgctacc cagacgttat cacaaacgtt
    82141 caatacgacc ttccagttat caaccttgtc ttctcaaatg ctgagtacgg cttcatcaag
    82201 aacaaatacg aagatacaaa caaacacttg tttggtgtag acttcacaaa cgctgactac
    82261 gctaaaattg cggaagctca aggagctgtt ggattcacag ttgaccgtat cgaagacatc
    82321 gatgcagttg ttgcagaagc tgttaaattg aacaaagaag gtaaaactgt tgtcatcgat
    82381 gctcgcatca ctcaacaccg tccacttcca gtagaagtac ttgaattgga tccaaaactt
    82441 cactcagaag aagctatcaa agccttcaag gaaaaatacg aagcagaaga actcgtacca
    82501 ttccgtctct tcttggaaga agaaggattg caatcacgcg caattaaata attcctctcg
    82561 ccgaaaatca aatatgaaac ttgtagactt tattctttga ttttcataga gcagaacttt
    82621 aaaagatcgg agcaatccgg tctttttatg gaggagagta aatgaattta aatcaattag
    82681 atattatcgt ttcaaatgtt ccccaagtct gtgctgactt ggagcatatt ttggataaaa
    82741 aggcagatta tgctgatgat ggttttgctc agtttacgat tggtagtcac tgccttatgt
    82801 tgtcacaaaa tcatttggtt cctttggaaa actttcagtc aggaatcatt attcatatcg
    82861 aggttgagga tgtagaccag aactacaaac ggttgaacga gcttggtata aaggttttac
    82921 acggaccaac tgtaaccgat tggggaacag agtccttatt agttcaagga cctgctggtc
    82981 tagtgcttga tttttatcgt atgaaatagg tcgcgtagtc atttgacgtt aaccttagct
    83041 atttttaaaa tagaaattga gaatatgaac tattgaaaga tcggagcaat ccggtctttt
    83101 tatataaaga aattgcatat aatactcata tgctttcaaa aagcattcta gtccatctcc
    83161 gattaacgat ggactttatc acctccttct ccagtccttg tatgacatct tgaagttgat
    83221 tcatgacatc ttccaaagtt cgaaaggcct tattcttaaa tccacgttta cgaatctctt
    83281 tccacacttg ttcaatgggt tcatctctgg tgtgtatgga ggaataaagg taaaaccaat
    83341 attagtcgga atctttaagg tacttgattt atgccatata gcattgtcca taacgagtaa
    83401 aagataatca tctggataag cttgtgaaag ctcttctaaa aaggcgttca tccactcagt
    83461 attacatcca ccagctatta agaaaaatga ttcgcctgta tgggcatcaa cagctccata
    83521 acaatagtga aattctcgta tatagtgact atggacatgt ggacctactc ctattggagc
    83581 ccaacaagat cccagtttac tgattctacc gaaaccagcc tcatcttggt acatcaagcg
    83641 aaccttacga aaacgtctac tgcttttaaa gcgctttctt ttcttcttga attgagattt
    83701 tatttttaga cgcgacaatg gtttgagcgt ctgctttcct aggatgttct ggacgtggca
    83761 taatatttcg ccaaccatgg tgcttcaaca gttgatagaa ggcatcacgt gtgtaggaac
    83821 gacctaactc ctttttataa gcctgaaata aggcatcaat tgtaacaaat tctcctgcct
    83881 ctgtagcctt caaatggcgg gcaagaaaga ctttcttttc ctcaatcgtc atatatgcat
    83941 ggttacggcc accacgtgtt tcttgaagga gagagtcgag ttcgaactcc tcatattttt
    84001 ttacatttcg ccaaatcgtt gtttgattac agtctatagt gtattgaatc tataacagta
    84061 caccttagct gctaaaatat ttctataaat tagtttgact ttcctgatag agttgttcac
    84121 atcttatttc aaactactat aaaagttcta taatctcttt ataagatttg cccatcagac
    84181 gaaatataat aaattgaaac tagaatagta cacctctact tctaaaacat tgttagaaat
    84241 cgatttgact gtcctgatcg atttgccctg ttcttgtttc gttttactat agaacgattt
    84301 gaaggcgttt atgatattta gctgtacgag agtctttaaa aagtgttttg atggtttgga
    84361 tttcttcttt agttgatttc atatcactat tatataatgc tttttgattt tagtatagta
    84421 ttatcgtaga aaatggactc ggtgctatgg atacaccgga tgagaatggt tatgtagcag
    84481 atgactatcg gattacttac ttagaggccc acatcaaggc catgcgagat gccatttaca
    84541 aagacggggt tgacttgctt ggttatacga catggggctg tatcgattcg gtttcagctg
    84601 gcacagggga aatgaataag cgctatggct ttatctatgt agatcgagat aatgtaggaa
    84661 atgggactct caaacgtagc aagaagaagt ccttctattg gtacatgtca tttatagcaa
    84721 tggtgtaagc atcgagtaga gcacatttgt ttactatttt tataaaatct tctccctgct
    84781 ttataagatg taaaaaagag ttcaattcga actctttttt tgctataatg aggggagaaa
    84841 aatcagacag gagattaaga tgtcagaacc attattttta caatcagtta tgcaagaaaa
    84901 aatctggggt ggtaccaagc tacgtgatga gtttggctac gacatcccaa gtgaaaaagt
    84961 cggagagtac tgggctatct cagctcatct aaatggtgtt tctaaagttg ccaatggtcg
    85021 ttacgaggga acagatcttg ctactttgta tgcggaacac cgtgaattat ttggcaatcg
    85081 tcctgagcct gtatttccgc ttttgactaa gattttggat gctaacgact ggctcagcgt
    85141 tcaagttcac ccagacgatg cttatggact agagcatgaa ggcgaacttg gaaaaacaga
    85201 atgctggtac atcatcgctg cggatgaagg ttcagagatt atctacggcc acaatgccaa
    85261 gtcaaaagaa gaactccgcc agcaaatcga ggataagaac tgggatgcgc tgttgacaaa
    85321 agtgccagtt aaagcaggag atttcttcta tgtaccaagc ggtaccatgc acgctatcgg
    85381 ggcgggtatc ttgattcttg aaacccagca gtctagcgat accacttacc gtgtctatga
    85441 ctttgaccgt aaggatgaca agggcaattt acgtgaactt caccttgaaa aatctatcga
    85501 tgtcttgaac attggtgaac ccgcaaatag ccgtccagtg acaatcaaag cagatgatct
    85561 acgttccact ctccttgtat ccaatgattt cttcgcagtt tacaaatggg aaattactgg
    85621 aaaagttaac tttgaaaaga cagctgacta cagcttgttg agtgtcttgg ctggtcaagg
    85681 tcaactaact gttgacggga aaaactatcc aatccaaaaa gggagacact ttatcctacc
    85741 aagtgatgtt gaagcttgga ctctggaagg gcaagattta gaattaattg ttagtcatcc
    85801 ataaaaaaga aagggcctga gttcattact caagtccttt ttgattacat aaattgggcg
    85861 atgaagacca cgatgatgat tggaatgacg gaacgaagaa acgaagaagg aagagccaga
    85921 cttggaacag tccttgtttc catgctcttt catcgagatg gagttcctcc attgcaagag
    85981 cctttttaaa gatatagcct gtaaaaagtg aaaggtagag agctccaaat ggcatgagga
    86041 gattgggaac caagaagttc atagcgtcaa agaaggtctt accaaaaatg tgaacatccg
    86101 ccatgacacc gtaagatagg gctgaaggaa tgccaaagac aaaggtcaaa attcctaaaa
    86161 taacactcca tttggcacgt ttgctgttat cctggttggt gatattgccc acattgatct
    86221 ccagcatcac gacagaagaa gtgacagtcg caaagaggaa gaggacgtag aaaatggttc
    86281 caaaaggcat cttgtcaaag agttgaggca agacgataaa gagcaagctc ggtccccctt
    86341 cagactggat attgaagggg gaccgagctt ggaaaatggc tagacctgcc atgatggata
    86401 tcgagatatt catggctacg atggagattc ctgactggac tagattggtt ttcttgtcca
    86461 agtaagaagc ataggtcaac atgactgtaa cccctagtga gagggcaaag aaagattgtc
    86521 ccagagcata gaggagacca gcgctagtca gttttgaaaa gtctggtttg aggaagtaaa
    86581 gaaccccttc catggcattt ggcaaactga gagagcgacc gatgataaca acaaagatga
    86641 taaagagcag gggcatcatg actttcgaag ctctttcaat ccctttttga accccacgtg
    86701 atacaataaa gatatttaat aagataaagg ctgcttgagc tcctagggca atggctggat
    86761 ttgaaatgat tgaagtaaat aactgagcat aatcacccgt tccaccaagt tggaacaatt
    86821 tcccaaactc aatacctaga tagactagaa tccatcctcc gataacactg taaaaagata
    86881 agaggataaa gagggcaaag gcgccaatcc aaccgataaa gttgtacttg ttattcttgc
    86941 ccagttttcc aaaggttttg atagcggaaa cgccagcact acggccaagg gcaaactcag
    87001 ccagcaggag agggaaaccg attaaaatag tggaaatgag aaagattagt aaaaagcctc
    87061 caccgccatt agcagcagtc atgtagggaa acttccaaac ggaaccaagc ccgatgaccg
    87121 agccagcaga tgctagaata aagccaagtt tcgaccccca ttgtgatttt tctgacatag
    87181 ttaaactctg atctcctttt tcaaaataag aaaaagctac ttgagttgtc aaatagcctt
    87241 ctgtttgatt gatagacttg actatcctat tatgttttct aaggtctgtc aagaaaacca
    87301 ttttcaagtt ttcacacctt tctcaaaaac gcttgactct gacctaaggg gaggggttat
    87361 actatcattg taaggaggaa atcatgtacc atataaaaga agctgcgcag ctttcaggtg
    87421 tctctgtcaa gaccccgccc tgcatcacta tgacaagata ggactcttgg tccccttaaa
    87481 gtcggaaaac ggctatcgaa cctatagtca agaggatttg gaacgccttc aggtcattct
    87541 ttactacaaa tatctaggct tttctttaga gaaaatagca gaactgttaa aggaagaaag
    87601 gacagattta ttgctccatt tgactaggta gttggactat ctaactcgcg aaaggcaaca
    87661 tctggatacc ttgatttcca ccttgcaaaa aactattcaa gaacaaaaag gagaaagaaa
    87721 aatgaccatt gaggaaaaat tcacgggatt tagctatcaa gacaatcaaa aataccacca
    87781 agaagcggta gagaaatatg gtcaagaagt catgggacaa gcgctcgaac gccaaaaagg
    87841 tcacgaagac gaggctacgg ccgcctttaa ccaagtcttt caaactttgg cacaaaatct
    87901 tcaagttggt ttacctgcaa cagcaaccga aaaccaggag caagcagcca agctcttgca
    87961 agccattcgc acttatggat ttgactgctc tattgaggta ttcggtcata tcggtaaagg
    88021 ttacgtctac aacccagagt ttaaggaaaa cattgacaag tttggttctg aaacagccca
    88081 gtacacgtca gatgccattg cggcttacgt tcagacaaat gcagaaaaaa taggctagga
    88141 atttcctagc ctatttttta cttcaaatca taaagccagt cgtcaccgtt tttgtagtaa
    88201 aagaattcac tgagatcttc ttctagaaac acacgaagca tatcagacat atcatcggtt
    88261 gcaagtttta gatgagaaag attttcaaag tcctcccacc aaactttccc ttcgtctgaa
    88321 gactggagtt caccagtaaa gtgttctgtc ttgtaaaaaa ggacgacata acgataatcc
    88381 ttgtcgtcat accagttttt gataccacag agttggggtt tggaaatgat cagaccagtt
    88441 tcttctttca cttcacgaat gacagcatcg acaaaggatt cgccacgttc aacatgacca
    88501 ccaggaaaag taatgccaga ccagtcggga ctaactcggt cttggaccag gaccttatct
    88561 ccgtttttaa tcatacacat gttaacaaat tcgactgcct ctcttctgtt cattcttcac
    88621 aacctttaat ctttaatcat aatgcagact tcccgccacc cagccggtac agagggcaga
    88681 agtgatgtta aagccacccg tgtgggcatt gatatccata acttcgcctg caaagtggag
    88741 gccaggtacc agcttacttt caagggtttt aggattgatt tccttgagac tgactccacc
    88801 cttggtaaca aaggactttg caagggacat ttttccagtt acaggaattt taagttcttt
    88861 aatggactgg acaagttgtt ctcgttcctt ttcagtcagt tgtttgactt tttcaggata
    88921 tccttgtaca aaaaattcgg ccaagcgttc tggtaacaag gtttttaaag cgtttttcaa
    88981 ggatttttcc cgattttctt ctagaaatgt aaccaagtcc ttctcagaaa gttgaggcaa
    89041 aacatcgagt gagagaacct ccccaccttt gacaaagcta gacatgcgta gggcagcagg
    89101 acctgacaaa ccaaagtggg taaagagtaa atcatgagtg atgacatgct taccataact
    89161 tagggtcaca tcgtccagag aaatcccttg taaggcttta tgtggaaaat ctgttaataa
    89221 aggactttca gcagcctcaa gatcggtgat ggtatgctta aaatggcgag caatctcgtg
    89281 accaaaacca gtcgaaccag tcgaaggata agacttacca cctgttgtga caatgagttt
    89341 ctcacaagtg aaggtttgat ccgctgactt aaggacaaac tggtcatcta cttttttaac
    89401 agaaacgatt tctatttgag tagcaacttg accacctagt tcggtgattt tcttttccaa
    89461 agcttcgata atagtccgag acttgtcact ggctggaaag acgcgtccgt ggtcttcgac
    89521 cttaagttta acaccatttt ctgtaaaaaa gttgatgatg tcatgattat cgaactggga
    89581 gaaaacactg taaagaaagc gtccgtttcc aggaattcca gctagcaggt tgtctaagct
    89641 accattgttg gtcacattgc aacgtccccc accagtccca gctaattttt ttccaagttt
    89701 ccgatttttt tcgatgagga gggttttctg tccataaaag ctactggaaa tcgtagccat
    89761 cataccagca ggtcccccac cgatgacaat agtatcaaaa tgtttcatag ctctattgta
    89821 ccacaaaaaa acaagagatg atggtcacct cttgtcaaga atgcaattaa tcaatttcat
    89881 agcccatcag caaaccgccc tcttctgcat agaaactgca gagaccagag gttggtagaa
    89941 ttttaatatc cgcttgtggg aaggtttcac ggattcgctc tgagagctgt tgacaacatt
    90001 tttcgttatt gcgttgggcc atgacaatac ggccaccagc atatccagct tttactaact
    90061 catcataggc agcttgaact gatttctttg atccccttgc tttttgtagc aattcgagag
    90121 ttccagtttc actagctttt ccgaccatac gaatgttgag aaggccaacg accgtaccga
    90181 taagcttgct caaacggccg ttcttcacca agttatcgac tttggctagg acaaagagca
    90241 acttagtttt ttcttgatag gcagtgatag cttcaaccac ttcttcaaaa gacaagccct
    90301 ggtcaatcaa gtcattcaat ttttctacga gtaggtcaac ttcaccacca gcagataaac
    90361 tatcaatcac atgaatctta gtgtcaggat ggtcttctag ataaatattc tttgctagtt
    90421 gagcactatt gtgactgcca gaaagggtac ctgtgatggt tactaggaaa atgtttttgg
    90481 caccttcaaa tgctcgcaaa tagtcatctg ggcttggaca agccgatttt gaagcttctg
    90541 cagttgcata catggtttcc atcatttggt caatatcgag actggcgtca tcaacaaaga
    90601 cctgatcagc tacttgaatg gttaagggga cacttacaaa ggttgtgtta atagctggtg
    90661 ttggcagttg acgataatca caaccagagt cagcaataat tttccaagtc atagaaattc
    90721 tccatctttg tcagttatac attgacaaag gttctgtctt tttttacaat tatatcatga
    90781 aaacccttga aacaaaagca tcatccgtct gttgtgacaa gtagaaagaa aatgttatgt
    90841 ctgaacgtag aatctctgaa aagtctcttg aaaatctcag aaaatcaaac caagaatcca
    90901 atttattaac cagagaagcc attgaaacag ccctcttgca actcttggaa aaaaaggagc
    90961 tgaccaagat tagtatttct gaattggtca aacgtgcagg tgtttcgcgt gcggcctttt
    91021 atcgcaatta tgactccaaa gaggaaattt tagagagcgt ctttaaacga actgtccaca
    91081 atattatgga acagctgcat cattacgatt taaagacaga cctttatttg gtttgggttc
    91141 accttttccg ggaggccaga aaggaagcta gagtgattca attggccttg gattaccatc
    91201 tggaaaaaat ctttgtccaa gccatgcagg aatttctaga aaaataccat gggaaatcaa
    91261 aaggtgtcag ctcttatctt cattccttct ggagctcagc catcgtctct gtccttctaa
    91321 aatggatcaa ggatggcatg aaggtaccag ctgaaaagat tgcagattta ggtttaccat
    91381 tttttaaaaa atagagaaaa aggagaaaag agatgactga aaaaagactg gcctgggatg
    91441 agtattttgc agcccaagcc ctactaattg cgaatcgttc cacttgtaaa cgtgctaaag
    91501 tgggcgcgat tctggtaaaa gataataagg ttatttccac tggttacaat ggttcggtgt
    91561 cagggactga gcattgtatt gatcacgaat gtttggtcat tgaaggccac tgtgttcgca
    91621 cccttcacgc tgaggtcaat gctatccttc aaggtgctga gcgtggtgtt cccaaaggct
    91681 ttacagccta tgtaacccat tttccttgtc tcaactgtac aaaacaattg cttcaggtcg
    91741 gctgcaagcg cgtggtttat atcaaccagt accgaatgga cgactacgcc caataccttt
    91801 atcaagaaaa agggacagaa ttgacccatt taccacttga gacagtacag acagctctta
    91861 aagaggctga tctaatgtaa aaattatcaa aaataaatgg cttagaaaga tttttaaacc
    91921 gttttttggt ataataagaa gaataaattg aaagaaggaa ttccaaaaat gggaaaaatt
    91981 gaagttatta atcacccact gattcaacac aaattgtcaa tcttgcgtcg tacagatact
    92041 tctacaaaag cttttcgtga gctagtagat gagattgcaa tgttgatggg gtatgaagta
    92101 cttcgtgatc ttccactaga agatgtggaa atcgaaacac caattacaaa aacagttcaa
    92161 aaacaattgg caggtaagaa attggccatc gtcccaatct tgcgtgcagg tatcgggatg
    92221 gttgatggtc tcttgagctt ggttccagct gctaaagttg gccacatcgg tatgtaccgt
    92281 gatgaagaaa cacttcaacc agttgaatac ttggtgaaat tgcctgagga cattgaccaa
    92341 cgtcaaattt ttatagtaga cccaatgttg gcaacaggtg gctcagcaat cttggctgtt
    92401 gattctctta aaaaacgtgg cgcatcaaat atcaaatttg tctgccttgt atctgctcca
    92461 gagggtgtaa aagcccttca agaagctcat ccagatgtag aaatctttac agcagccttg
    92521 gatgaacgtt tgaacgaaca cggttatatc gttccaggtc ttggagatgc tggagaccgc
    92581 ttgttcggta caaaataaga tcgaaaagaa gaatgacttg gaaaagtatt tccagtcacg
    92641 aaaggaggtt gggtttttgt ttctgtctaa tgaaagcaga gcaaaaattt gacctttttt
    92701 gaccaagata ttataatagt cttatcttca gtcatttgac caacaaaatt aaaactcaaa
    92761 aggagaaatg aatgattcct gtagttattg aacaaacaag ccgtggagaa cgttcttacg
    92821 atatttactc acgtcttctc aaagaccgca tcattatgct gacaggtccg gttgaagaca
    92881 atatggctaa ctctgttatt gcccaattgc ttttcttgga tgcccaagat agtacaaaag
    92941 atatttacct ttatgtcaat acaccaggtg gttctgtttc agctggtttg gcaatcgtag
    93001 ataccatgaa ctttatcaag gcagatgtcc aaaccattgt tatgggaatg gctgcatcta
    93061 tgggaacagt catcgcatca agtggagcaa aaggcaaacg tttcatgctt ccaaatgctg
    93121 aatacatgat tcaccaacca atgggcggta caggtggtgg tacccaacaa actgatatgg
    93181 ctatcgctgc agaacacttg ctcaaaactc gtaatacctt ggaaaaaatc ttggctgaaa
    93241 attcaggtca gtcaatggaa aaagtccatg cagatgcaga acgtgataac tggatgagcg
    93301 cccaggaaac acttgaatat ggctttattg atgaaattat ggccaacaat tcattgaact
    93361 aatgatgata gaaggcaaac tcgactgggt ttgctttttt tggtataata gggagagatt
    93421 tcttagaaag aggatttatc atgtttgaaa aagtcaatcg ctctggcttg attatctatc
    93481 tttactataa tcgtgatgcc aaaaaactgc aggattatgg agatattacc tatcattcca
    93541 agaaacatcg ttacttacaa ctctatgttc caactcaaga agtggagcaa ttggtcggac
    93601 gcttgagcaa ggaaaaattt attaaaaaag ttagggtttg tcatatccaa gagttggaaa
    93661 caccctttgt gggcaatctt tatcgatagg aaaacgttat catcgaaaaa gttcaaggaa
    93721 aacattgaca attttctgat aattcggtat attcttaaca gactatttaa gaaataagga
    93781 gacaaaaaga tgaagaaaaa atttgcccta tcgtttgtgg cgcttgcaag tgtagcactt
    93841 cttgcagcct gtggagaagt gaagtctgga gcagtcaaca ctgctggtaa ctcagtagag
    93901 gaaaagacaa ttaaaatcgg gtttaacttt gaagaatcag gttctttagc tgcatacgga
    93961 acagctgaac aaaaaggtgc ccaattggct gttgatgaaa tcaatgccgc aggtggtatc
    94021 gatggaaaac aaatcgaagt agtcgataaa gataataagt ctgaaacagc tgaggctgct
    94081 tcagttacaa ctaaccttgt aacccaatct aaagtatcag cagtcgtagg acctgcaaca
    94141 tctggtgcga ctgcagctgc ggtagcgaac gctacaaaag caggtgttcc cttgatctca
    94201 ccaagtgcga ctcaagatgg attgactaaa ggtcaagatt acctctttat tggaactttc
    94261 caagatagct tccaaggaaa aattatctca aactatgttt ctgaaaaatt aaatgctaag
    94321 aaagttgttc tttacactga caatgccagt gactatgcta aagggattgc caaatctttc
    94381 cgcgagtcat acaagggtga aatcgttgca gatgaaactt tcgtagcagg tgacacagac
    94441 ttccaagcag cccttacaaa aatgaaaggg aaagactttg atgctatcgt tgttcctggt
    94501 tactataatg aggctggtaa gattgtaaac caagcgcgtg gtatgggaat tgacaaacca
    94561 atcgttggtg gtgatggatt caacggtgag gagtttgtac aacaagcaac tgctgaaaaa
    94621 gcatcaaaca tctactttat ctcaggcttc tcaactactg tagaagtttc agctaaagct
    94681 aaagccttcc ttgacgctta ccgtgctaag tacaatgaag agccttcaac atttgcagcc
    94741 ttggcttatg attcagttca ccttgtagca aacgcagcaa aaggtgctaa aaattcaggt
    94801 gaaatcaagg ataaccttgc taaaacaaaa gattttgaag gtgtaactgg tcaaacaagc
    94861 ttcgatgcag accacaacac agtcaaaact gcttacatga tgaccatgaa caatggtaaa
    94921 gttgaagcag cagaagttgt aaaaccataa tagaaaaatg ttgaaatagg gaatgagcct
    94981 ttgactcact ccctgtttcg atatttaata ctcttcgaaa atctcttcaa actgcgtcaa
    95041 cgtcgccttg gattatatat gtgactgact tcgtcagtct tatctacaac ctcaaagcag
    95101 tgctttgagc aacctgcggc tagtttccta gtttgctctt tgattttcat tgagtataag
    95161 aacctatcaa aaagtgaggg aaacccctcg gaattataaa tagaaagagt gaatcttatg
    95221 ctccaacaac tcgtaaatgg tttgattcta ggtagtgttt acgcgctgtt agccctagga
    95281 tataccatgg tttacggaat tatcaagctc atcaacttcg cccatggtga tatttatatg
    95341 atgggagcct ttatcggtta tttcttgatc aattctttcc aaatgaattt ctttgtagcg
    95401 cttattgtag ctatgctagc gacagctatt cttggtgtcg tgattgagtt tcttgcttac
    95461 cgacctttgc gccactctac tcgtattgct gttttgatta cggctattgg ggtttctttc
    95521 ctattggagt atggaatggt ctatctggtt ggtgccaata cccgtgcctt ccctcaagcg
    95581 attcaaacag ttcgatatga tttgggacca attagcttaa caaatgtgca gttaatgatt
    95641 ttggctattt ccttgatttt gatgattttg ttacaagtca ttgtccaaaa gactaagatg
    95701 gggaaagcca tgcgtgcagt atcagtagat agcgacgcgg cgcaattgat ggggatcaat
    95761 gtaaaccgta cgattagctt taccttcgct ttgggttctg ctcttgcggg tgcggctggt
    95821 gttctgattg ctctttatta taactctctt gagcctttga tgggggttac tccaggtctt
    95881 aaatctttcg ttgccgcagt acttggtggt atcggaatta ttcctggtgc ggctcttggt
    95941 ggctttgtga ttggtctatt ggaaaccttt gcgactgcct ttgggatgtc agatttccgt
    96001 gatgccattg tttatggaat cttgttgttg atcttgattg tccgcccagc tggtatcctt
    96061 ggtaagaatg tgaaagagaa ggtgtaaacg atgaaggaaa atttaaaagt taatattcta
    96121 tggttactcc ttttgttagc tggctatagc ttgattagtg tactggtttc agtcggagta
    96181 cttaatctat tctatgtaca gattttacag caaattggaa ttaatattat tttggctgtt
    96241 ggtctcaact taatcgttgg tttttcagga caattttcac ttggtcatgc tggtttcatg
    96301 gcgattggtg cctatgcagc agctattatt ggttctaaat taccaaccta cggtgccttc
    96361 tttggagcta tgcttgtagg ggctttgctt tcaggagcag ttgccttact tgtcggcatt
    96421 ccaaccttgc gcttgaaggg ggactatctt gcggtagcaa ctctgggtgt ttctgaaatt
    96481 atccgtatct ttatcatcaa tggtggaagc cttacaaatg gtgcggcagg tatcttaggg
    96541 attcctaact ttacaacttg gcaaatggtt tacttctttg tcgtgattac aaccattgca
    96601 accttgaact tcttgcgtag cccaattggt cgttcaaccc tctctgttcg tgaagatgaa
    96661 atcgctgctg agtcagttgg ggttaatacg actaaaatta aaatcatcgc ttttgtcttt
    96721 ggtgccatta ctgcaagtat tgctgggtca cttcaggcag gatttatcgg gtctgttgta
    96781 ccgaaagatt acaccttcat caactcaatc aacgttttga ttattgttgt atttggtgga
    96841 ctcggttcca ttacaggtgc gattgtttcg gctattgttc tgggaatttt gaatatgctt
    96901 ctccaagatg ttgctagtgt gcgtatgatt atttacgctt tggccttggt attggtaatg
    96961 attttcagac caggtggact ccttggaaca tgggaactga gcctatcacg tttctttaaa
    97021 aaatctaaga aggaggaaca aaactaatgg cattacttga agtaaaacag ttaaccaaac
    97081 attttggtgg tctaacagct gttggagatg tgactcttga attgaacgaa ggggaactgg
    97141 ttggattaat cggtccaaac ggagctggga aaaccaccct tttcaacctt ttgaccggtg
    97201 tttatgaacc aagcgaggga acagtaaccc tagatggtca ccttttgaat gggaaatcac
    97261 cttataagat tgcctctttg ggacttggac gtactttcca aaatatccgt ctctttaaag
    97321 atttaacagt tttagacaat gttttgattg cttttggaaa ccatcacaaa caacatgttt
    97381 ttactagttt cttacgctta ccagcttttt acaagagtga aaaagaatta aaggctaaag
    97441 ctttggaatt gttgaaaatc tttgatttag atggtgatgc agagactctt gctaaaaatc
    97501 tttcctacgg acaacaacgt cgtttggaaa ttgttcgtgc ccttgctacg gaacctaaaa
    97561 ttctcttctt agatgaacca gcagcaggta tgaacccaca ggaaacagcc gaattgactg
    97621 agttaattcg tcgtatcaaa gatgaattta agattacaat catgttgatt gaacacgata
    97681 tgaatctggt catggaagta acagaacgta tctacgtact tgaatatggc cgtttaattg
    97741 ctcaaggaac tccagacgaa attaagacca ataaacgcgt tatcgaagct tatctaggag
    97801 gtgaagccta atgtctatgt taaaagttga aaatctttct gtgcattacg gtatgatcca
    97861 agcagtccgt gatgtaagct ttgaagttaa tgaaggagaa gttgtttccc ttatcggtgc
    97921 caacggtgca ggtaagacaa ctattcttcg caccttgtca ggtttggttc gaccaagttc
    97981 aggaaagatt gaatttttag gtcaagaaat ccaaaaaatg ccagctcaga aaattgtggc
    98041 aggtggtctt tcacaagttc cagaaggacg ccacgtcttt cctggcttga ctgttatgga
    98101 aaatcttgaa atgggagctt tcttaaagaa aaatcgtgaa gaaaatcaag ctaacttgaa
    98161 gaaggttttc tcacgctttc ctcgtcttga agaacgtaag aaccaagatg cagctactct
    98221 ttcaggaggg gaacaacaaa tgcttgccat gggacgcgct cttatgtcaa caccaaaact
    98281 tcttctttta gatgaaccat caatgggact tgccccaatc ttcatccaag agatttttga
    98341 tatcattcaa gatattcaga agcaaggaac aaccgtcctc ttgattgaac aaaatgccaa
    98401 taaagcactt gcaatctctg accgaggata tgtactggaa acagggaaaa tcgtcctatc
    98461 aggaacagga aaagaactcg cctcatcaga agaagtcaga aaagcatatc taggtggcta
    98521 aaacaatcca gtggattgtt ttagtcggca gatgaagatt acgaagtaat catcattata
    98581 gtctgggaga ctagtttagg ttgcagataa agattgcgaa gcaatcatca aatccagtgg
    98641 attgttttag tcggcagatg gagattacga agtaatcatc aatatagtcc gggggacctt
    98701 tttagtcggt agattgagat tgcaaacaaa tctgcatcta cattgaaagc ttaatttcta
    98761 ataattgaaa aaatcgaatg aaaaatttct taccttcatt cacagagctc gatttcagag
    98821 ctctttttgc tagcttattc atacttttct gaatttcgaa aaagaaatgt aagcgtttga
    98881 tagatttaca aaaagattgt ataataggga taagaataga aaaggagaag tctcatggca
    98941 gttaaagatt ttatgacccg caaggtagtt tatattagtc cagatacaac agtatctcat
    99001 gcagcagatt tgatgagaga gcaaggtttg caccgtctgc ctgttatcga aaatgatcaa
    99061 ttagttggtt tggtgactga gggaaccatt gcacaagcaa gtccatctaa agcaacaagt
    99121 ctttctatct atgagatgaa ttatcttctg aataagacaa aagtaaaaga tgtcatgatt
    99181 cgcgatgttg tcactgtctc aggctatgct agtctagaag atgcaactta tctgatgttg
    99241 aaaaataaga ttagtattct ccctgtcgta gataaccatc aagtatacgg agttattact
    99301 gaccgtgacg ttttccaagc ctttcttgaa attgcaggtt atggcgaaga agggattcgt
    99361 gtacgctttg ttacagaaga tgaagttggt gttcttggaa aaattgtttc tttgattgta
    99421 gaagaaaatt tgaatatctc ccatacagtc aatattccgc gtaaggatgg taaggtgatt
    99481 atcgaagtgc aaatcgatgg atcaattgat ttaccagcct tgaaagaaaa atttgaagca
    99541 aatggtattc aagtggaaga aatcgctcgc acttcagcaa aagtcttgta agaagggaag
    99601 cccaaaggct tcttttttca tgaaaagggg attagagaaa aagatggaaa gaaatgataa
    99661 aatatgctat aatgaaataa tgtaaaaaag gagtatttat ggacatttca gtaattcgtc
    99721 agaaaattga cgcaaatcgt gaaaaattag cttctttcag ggggtctctt tgacctcgaa
    99781 gggctagagg aagagattgc catcttggaa aacaagatga cagaacctga tttttggaac
    99841 gataatattg cagcccaaaa aacgtcgcaa gaattaaatg aattaaaaaa cacttacaat
    99901 accttccata agatggaaga gttgcaggat gaagtcgaaa ttttattgga ttttttggct
    99961 gaagacgagt cagtgcatga tgaactggta gcgcagttag ccgaacttga taagataatg
   100021 accagctacg agatgactct actcttgtca gaaccttatg accacaacaa tgccatcttg
   100081 gaaatccatc caggttctgg tggtactgag gcgcaggact ggggtgatat gttgcttcgt
   100141 atgtatactc gttatggtaa tgctaaaggc tttaaagtgg aagtgttgga ttaccaagca
   100201 ggtgatgagg ctggtattaa gtcggtaact ttatcatttg aagggcctaa tgcctatggt
   100261 ctcctcaagt cagaaatggg tgttcaccgc ttagtgcgaa tctcaccatt tgactctgcc
   100321 aaacgtcgcc atacctcttt cacatctgta gaagtgatgc cagaattgga tgatactatt
   100381 gaagtggaaa tccgtgaaga tgatatcaag atggatacct tccgttcagg tggtgccggt
   100441 ggacaaaacg tcaataaggt ttcaacaggt gtacgtttaa cccacattcc aactggaatt
   100501 gttgtccaat caacagtgga tcgtacccag tatggaaata gagatcgtgc catgaagatg
   100561 ttgcaggcta agctctatca aatggagcaa gagaagaagg ctgcagaggt agattctctc
   100621 aaaggtgaga aaaaggagat cacttgggga agccaaatcc gttcttatgt cttcacgcct
   100681 tatactatgg taaaagatca ccgaactagc tttgaggttg ctcaggtaga taaggttatg
   100741 gatggggact tagatggttt tatcgatgct tatctcaagt ggcgaattag ctaagataga
   100801 aaggaactca catgtcaatt attgaaatga gagatgtcgt taaaaaatac gacaacggaa
   100861 cgactgctct acgcggtgtt tcggttagcg ttcaaccggg ggaatttgct tacatcgtag
   100921 gaccttcagg agcagggaag tcaactttta ttcgttctct gtatcgtgaa gtaaaaatcg
   100981 ataaaggaag cctatcagtt gctggtttta atctggttaa gatcaaaaag aaagatatcc
   101041 cgcttctacg tcgtagtgtt ggggttgtct tccaggatta taaattgtta ccaaagaaaa
   101101 ctgtctatga aaatattgct tacgctatgg aagtaatcgg ggaaaatcgc cgtaatatca
   101161 aaagacgagt gatggaagtt ttggacttgg ttggattgaa gcataaggtt cgttctttcc
   101221 caaatgaact ctcaggtggg gagcaacagc ggattgcgat tgcgcgtgca attgtaaata
   101281 atcccaaagt attgatagct gatgagccaa caggaaatct ggatccggat aattcatggg
   101341 aaattatgaa tcttttggaa cggattaacc tacaaggaac aactattttg atggcgactc
   101401 ataatagcca gattgtaaat accttgcgcc accgtgtcat tgccattgaa aatggccgtg
   101461 tcgttcgtga cgaatcaaaa ggagagtatg gatacgatga ttagtagatt ttttcgccat
   101521 ttatttgaag ccttaaaaag tttgaaacga aatggttgga tgacagtagc tgctgtcagt
   101581 tcagtcatga ttactttgac cttggtggca atatttgcat ctgttatttt caatacagcg
   101641 aaactagcta cagatattga aaataatgtc cgtgtagtag tttatatccg aaaggatgtg
   101701 gaagataata gtcagacaat tgaaaaagaa ggtcaaactg ttacaaataa tgactaccac
   101761 aaggtatatg attctttgaa gaacatgtct acggttaaaa gtgttacctt ttcaagtaaa
   101821 gaagaacaat atgaaaaatt aaccgagata atgggagata actggaaaat ctttgaagga
   101881 gatgccaatc ctctctatga tgcctatatt gtagaggcaa acactccaaa tgatgtaaaa
   101941 actatagccg aagatgctaa aaaaattgaa ggtgtctctg aggttcaaga tggcggtgcc
   102001 aatacagaaa gactcttcaa gttagcttca tttatccgtg tttggggact agggattgct
   102061 gctttgttaa tttttatcgc agttttcttg atttcaaata ccattcgtat taccattatt
   102121 tcccgcagtc gcgaaattca aatcatgcgc ttggtcggag ctaaaaacag ttatatccgt
   102181 ggaccgttct tgttagaagg agcctttatc ggtttattgg gagctatcgc accatctgtt
   102241 ttggtcttta ttgtttatca aattgtttac caatctgtca acaaatcgtt ggtagggcaa
   102301 aatctatcca tgattagtcc agatttattt agtccgttga tgattgccct actatttgtg
   102361 attggggttt tcattggttc attgggatca ggaatatcca tgcgccgatt cttgaaggtt
   102421 taggtaaaat agctgctttt atgaggagat tgtaaaatct ccttttttgc tacaagagtt
   102481 tttgaaaaga gatgcgcaga agaaaagagc ttccaaagaa gtcccccaga gaagacttct
   102541 tgatggctaa tttgaacttg aaatttggcg cactagaaat tttttagaaa aaagtgtaat
   102601 ttttttataa aagcctttac aaaaaaaatt aaagtggtat aattaaatca tagaaagtgc
   102661 aaacgttttc gtaaaacgtt tgcctaaata aaaataaagg agatttgaat gatgaaagat
   102721 acattcaaaa atgtcttgtc tttcgaattt tggcaaaaat tcggtaaggc tttgatggta
   102781 gttatcgcgg ttatgccggc tgctggtttg atgatttcaa tcggtaagtc tatcgtgatg
   102841 attaacccaa cctttgcacc acttgtcatc acaggtggaa ttcttgagca aatcggttgg
   102901 ggggttatcg gtaaccttca cattttgttt gccctagcca ttggaggaag ctgggctaaa
   102961 gaacgtgctg gtggtgcttt cgccgctggt cttgccttca tcttgattaa ccgtatcact
   103021 ggtacaatct ttggtgtatc aggcgatatg ttgaaaaatc cagatgctat ggtaactact
   103081 ttctttggtg gttcaatcaa agttgctgat tactttatca gtgttcttga agctccagcc
   103141 ttgaacatgg gggtattcgt agggattatc tcaggttttg taggggcaac tgcttacaac
   103201 aaatactaca acttccgtaa acttcctgat gcactttcat tcttcaacgg gaaacgtttc
   103261 gtaccatttg tagttattct tcgttcagca atcgctgcaa ttctacttgc tgctttctgg
   103321 ccagtagttc aaacaggtat caataacttc ggtatctgga ttgccaactc acaagaaact
   103381 gctccaattc ttgcaccatt cttgtatggt actttggaac gtttgctctt gccatttggt
   103441 cttcaccaca tgttgactat cccaatgaac tacacagctc ttggtggtac ttatgacatt
   103501 ttaactggtg cagctaaagg tactcaagta ttcggtcaag acccactatg gcttgcatgg
   103561 gtaacagacc ttgtaaacct taaaggtact gatgctagtc aatatcaaca cttgttagat
   103621 acagtacatc cagctcgttt caaagttgga caaatgatcg gttcattcgg tatcttgatg
   103681 ggtgtgattg ttgctatcta ccgtaatgtt gatgctgaca agaaacataa atacaaaggt
   103741 atgatgattg caacagctct tgcaacattc ttgacagggg ttactgaacc aatcgaatac
   103801 atgttcatgt tcatcgcaac acctatgtat cttgtttact cacttgttca aggtgctgcc
   103861 ttcgctatgg ctgacgtcgt aaacctacgt atgcactcat tcggttcaat cgagttcttg
   103921 actcgtacac ctattgcaat cagtgctggt attggtatgg atatcgttaa cttcgtttgg
   103981 gtaactgttc tctttgctgt aatcatgtac tttatcgcaa acttcatgat tcaaaaattc
   104041 aactacgcaa ctccagggcg caacggaaac tacgaaactg ctgaaggttc agaagaaacc
   104101 agcagcgaag tgaaagttgc agcaggctct caagctgtaa acattatcaa ccttcttggt
   104161 ggacgtgtaa acatcgttga tgttgatgca tgtatgactc gtcttcgtgt aactgttaaa
   104221 gatgcagata aagtaggaaa tgcagagcaa tggaaagcag aaggagctat gggtcttgtg
   104281 atgaaaggac aaggggttca agctatctac ggtccaaaag ctgacatttt gaaatctgat
   104341 atccaagata tccttgattc aggtgaaatc attcctgaaa ctcttccaag ccaaatgact
   104401 gaagcacaac aaaacactgt tcacttcaaa gatcttactg aggaagttta ctcagtagca
   104461 gacggtcaag ttgttgcttt ggaacaagta aaggatccag tatttgctca aaaaatgatg
   104521 ggtgatggat ttgcagtaga acctgcaaat ggaaacattg tatctccagt ttcaggtact
   104581 gtgtcaagca tcttcccaac aaaacatgct tttggtattg tgacggaagc aggtcttgaa
   104641 gtattggttc acattggttt ggacacagta agtcttgaag gtaaaccatt tacagttcat
   104701 gttgctgaag gacaaaaagt tgcagcagga gatctccttg tcacagctga cttggatgct
   104761 atccgtgcag caggacgtga aacttcaaca gtagttgtct tcacaaatgg tgatgcaatt
   104821 aaatcagtta aattagaaaa aacaggttct cttgcagcta aaacagcagt tgctaaagta
   104881 gaattgtaat atacttgagg ttggaagctg tattccaacc tcttattttg ggagaaaaga
   104941 atgaaatttt taacactcaa tactcacagt tggatggaga aagaagcaga ggaaaaattc
   105001 cagattttgc ttgaagatat tcttgaaaag gactatgatt tgatttgttt ccaagaaatc
   105061 aatcaggaga tgacctcgtc agaggtggag gttaatgacc tttatcaagc tttgccagca
   105121 gctgagccta ttcaccaaga ccattatgtt agactcttgg ttgaaaagtt gttagagcaa
   105181 gggaaaaatt actactggac ctgggcttat aaccatatcg gctatgaccg ctaccacgaa
   105241 ggtgtggcta tcttgtctaa aacacctatt gaagccagag aaattttggt ttcagatgtg
   105301 gatgatccaa cagactatca tactcgccgt gttgccctag ctgaaactgt agtcgatggc
   105361 aaggagctag cagttgccag tgttcatctc tcttggtggg ataaaggttt ccaagaagaa
   105421 tgggcacgat ttgaggctgt cttgaaaaaa ttgaacaagc cacttttact agctggagat
   105481 tttaacaacc cagcaggtca ggaaggttac caagctattt tagctagtcc attaggctta
   105541 caagacgcat ttgaagttgc tcaagagaaa agtggtagct atactgttcc gcctgaaatt
   105601 gatggctgga aagggaacac tgaacccctt cgaatcgatt atgtctttac taccaaagag
   105661 ttagcggtgg aaaatttaca tgtcgtattt gatggtaaca agagtccaca agtgagtgat
   105721 cactatggct tgaatgctat attaaactgg aaataataac tgaaaagagg ttggaactat
   105781 aaaattccag ccttttctta ctagagaagc tactggaaat agcctaaata agtgagacta
   105841 ctgtaatgga ataaaatatg gtataattga taagatagat agaatcgagg atgttatgtc
   105901 atttacgaaa tttcaattta aaaactatat tagagaagcc ttgaaggagt taaaatttac
   105961 aactccaaca gaggtgcaag acaagttgat tcctattgtt ttggcaggtc gtgacctagt
   106021 aggagaatca aaaacaggtt caggtaagac tcatactttc ttgttaccga ttttccagca
   106081 attagatgaa gctagcgata gtgtacaagc agtgattact gcaccgagtc gtgagttggc
   106141 tactcaaatt taccaagtag cgcgtcagat ttcagctcac tcagatgtcg aagttcgtgt
   106201 ggttaattat gtgggtggta cggataaggc tcgccagatt gagaaattgg aaagcaatca
   106261 gcctcatatt gttattggaa caccaggccg tatctacgac ttggttaaat ctggtgattt
   106321 agctattcat aaagccaaga catttgttgt tgatgaagca gatatgacct tggatatggg
   106381 attcttggaa actgttgata agattgctgg cagtcttcca aaagacttgc aattcatggt
   106441 cttctcagcg actatcccac aaaaactgca accattcttg aaaaaatact tatcaaatcc
   106501 tgttatggag aaaattaaga ccaaaacggt tatttctgac accattgata attggttgat
   106561 ttcgaccaag ggacatgata agaatgctca aatttaccag ttgactcagt tgatgcagcc
   106621 gtatttggca atgatttttg ttaacactaa aacgcgtgct gatgaattgc attcatatct
   106681 gactgctcaa ggcttgaagg ttgcaaaaat ccatggagat attgcccctc gtgaacgcaa
   106741 gcgaatcatg aatcaggtgc aaaatctgga ttttgagtat attgtcgcaa cagatttagc
   106801 agcgcgtggg attgacattg aaggtgtcag ccatgtcatc aatgatgcca ttccgcaaga
   106861 cttatctttt tttgttcatc gtgttggtcg tactggacga aatggcctac caggtacagc
   106921 tattaccctt tatcagccaa gtgatgactc ggatatccgt gagttggaga aattgggaat
   106981 caagtttagt cctaagatgg tcaaagacgg ggaatttcaa gatacctatg accgtgatcg
   107041 tcgtgccaac cgtgagaaaa aacaagataa acttgatatc gaaatgattg gtttggttaa
   107101 aaagaaaaag aaaaaagtca aaccgggtta taagaagaaa attcaatggg cggttgatga
   107161 aaagcgccgt aaaaccaagc gtgctgaaaa tcgcgctcgc ggtcgtgcag agcgtaaagc
   107221 taaacgccaa acattttaat agaaattgtt ggagtattga gctccaactt tttgctttat
   107281 gagaacgaac tatctaaacc gaaacactac attaaagact gcaaattgcg attaaaaatg
   107341 gtataatgat aaagttatat agtcccgata agatggtagg tatttattac gaagagtttt
   107401 cctatcagta ctttgtaact ctataacaat attttttaag gggggacatt tttatgtcag
   107461 aacgtaaatt attcacgtct gaatctgtat ctgaggggca tccggataag attgcagacc
   107521 aaatttcaga tgcgattttg gatgctattt tagcaaagga tccagaggcg cacgttgctg
   107581 ctgaaacagc tgtatatact ggttctgtcc acgtttttgg tgaaatttct acaaatgcct
   107641 atgtggatat taaccgtgtg gttcgtgata ccattgcaga gattggttat accaatacag
   107701 aatatggatt ttctgctgag acggtgggag tacacccatc tttggtggaa caatctcctg
   107761 acatcgctca aggtgttaac gaagccttgg aggttcgtgg aaatgctgat caagatccac
   107821 tggacttgat tggagcaggt gaccaagggc tcatgtttgg atttgcagta gatgaaacag
   107881 aagagctcat gccattgcca attgcactca gtcataaatt ggttcgtcgt ctggcagaac
   107941 ttcgtaagtc tggagaaatt agctatctcc gtccagatgc aaaatcacaa gttacagttg
   108001 agtacgatga aaatgaccgt ccggtacgtg tagatacagt cgttatttct actcagcatg
   108061 atccagaggc cactaatgaa caaatccatc aagatgtgat taacaaggtc atcaaagaag
   108121 ttattccatc ttcttatctt gatgataaga caaaattctt tatcaatccg acaggtcgtt
   108181 ttgtaatcgg tggtcctcaa ggggactcag gtttgactgg tcgtaagatt attgtagata
   108241 cttatggtgg ctactctcgt catggtggtg gtgccttctc tggtaaagat gcgactaagg
   108301 tggatcgttc agcctcttat gcggctcgct atattgccaa gaatatcgtt gcagcaggcc
   108361 ttgctaagaa ggcagaagtg cagttggcct atgctatcgg tgttgcgcaa cctgtttctg
   108421 ttcgtatcga tactttcggt acaggaacag tagctgaaag tcaacttgaa aaagcggctc
   108481 gtcaaatctt tgaccttcgc cctgcaggga ttatccaaat gctggacctc aagcgtccaa
   108541 tttaccgtca aacatcggct tacggtcaca tgggacgtac agatattgat cttccatggg
   108601 aacgtttgga taaggtagat gctttgaaag aagcagtaaa ataagatttt aagaggggaa
   108661 cgtcctctct tttttatagt ttttaactat actgggatac tgttctgaaa atccattttg
   108721 cgaaagtaga gatttacatg tatagtagat tgaaactaga atagtacacc tcaacttcta
   108781 aaacattgtt agcaatcaat ttgactgtcc tgatcgattt ctcctgttct tgtttcattt
   108841 tactatattt ctttaaaaat gataaaggtt gagatttctc ctcgtaatag ataatcatgg
   108901 ggatatttca atccaaagtt ttattcgtta tcacttgact attgcaaggt tttctagagc
   108961 aacagagtca tggaatggac tcatggttga gatttctcct tgttgcttgg acttcattca
   109021 aaagtctgtt acccaagcct tgttcaaact tccaatacac tagctgtttt catagcatga
   109081 cttctgtact agactttctt ttccgaataa atagatagaa ccacagaatc tagtaaacct
   109141 agaattaaaa ttatggtata atattagcaa taaaagaaat ctggaggatt agaatcatgg
   109201 tatcaacgaa aacacaaatt gctggttttg agtttgacaa ttgcttgatg aatgcagcag
   109261 gtgtggcttg tatgacgata gaggagttag aagaggtcaa aaactcagcg gcaggaacct
   109321 ttgttactaa gacagcgacc ttggacttcc gtcaggggaa tcctgagcca cgctaccaag
   109381 atgttccact tggttccatc aactctatgg gcttgccaaa taatggctta gactattatt
   109441 tggattatct tttagatttg caggaaaaag agtcgaaccg aactttcttc ttatctctgg
   109501 tcggcatgtc tccagaggaa acccatacta ttttgaaaaa agttcaagag agtgattttc
   109561 gtggtctgac tgagctaaat ctttcctgtc caaatgttcc aggtaaacct cagattgcct
   109621 atgattttga gacaacagac cggattttgg cagaagtgtt tgcttacttc accaaacctc
   109681 ttggaattaa attgccacct tattttgata ttgttcactt tgatcaagcg gcagctattt
   109741 tcaacaaata tccgctcaag tttgtcaact gcgttaactc tatcggaaac ggcctctata
   109801 tagaagacga atctgtcgtt attcggccta agaatggttt tggtggaatt ggtggagaat
   109861 acatcaaacc gactgctcta gccaatgttc acgcctttta tcaacgttta aatcctcaaa
   109921 tccaaattat cggaacaggt ggcgttctga ctggtcgaga tgcctttgaa cacatcctct
   109981 gtggagcaag tatggtgcag gtgggaacga cccttcacaa agaaggcgtc agtgcttttg
   110041 accgcattac caatgaactg aaagcaatca tggtggaaaa aggctacgag agcttagaag
   110101 atttccgtgg gaaattgcgc tatattgact aaattaaatc gaaaaatctg aagaaaggag
   110161 agacgatgct agccattgaa gaaagtcaga agttgacttt atcaaattta ccgagcctga
   110221 gcctatttac agggacagat cagggtcagt ttgaagtgat gaagagtcaa gtgttgaaac
   110281 agattgggta tgattctgct gacctcaact ttgcctactt tgatatgaaa gaagtagttt
   110341 acaaggatgt ggaactggag ttggtcagcc ttcctttctt tgcggatgag aaaatcgtga
   110401 tattagatta ttttatggat atcacgactg ctaagaaacg ctttttgaca gatgatgagc
   110461 ttaagtcatt tgaggaatac cttgacaatc cttctccaac aaccaagttg ataatctttg
   110521 cagaaggaaa gctggatagc aaaagacggt tagtcaaatt acttaagcgt gatgccaagg
   110581 ccttcgatgc agtagaagta aaagaacaag aattgcgcca gtatttccaa aagtggagtc
   110641 agaaacaagg tctgcagttt accaatcatt cttttgaaaa tctcctcatc aagtcggggt
   110701 ttcaatttag cgaaatccag aaaaatcttc tctttttaca gtcctataag gcggattctg
   110761 ttatcgagga agaggatatt gttaacgcaa ttcccaagac cttgcaggac aatatttttg
   110821 atttaactca gtttattctg actaaaaaga tggatcaggc gcgcgatttg gtgagagact
   110881 tgaccttgca aggggaagat gaaatcaaac taattgcagt catgctggga caatttcgga
   110941 cttttactca ggtgaagatt ttggcggagt ctggccaaac agaatcgcag attgcaagta
   111001 gtttaggtag ttatctggga cgtaacccaa atccttatca aatcaagttt gcattaagag
   111061 attcgagagg actttctttg agctttctga agcaagctat ttcctatttg attgagacag
   111121 actatcagat taagacaggt ctttatgaaa aaggtttcct ttttgaaaag gcactcttac
   111181 agattgctag tcaggtcaat tgacatttgt tgaaactaca acccgcgtca ggattatctt
   111241 gtcgtgggtt tcttgctgat ttgcttatct ataagcaaaa aacttgaaaa aagtgaatgt
   111301 ttgcgttatc attttcatat agaaagaaaa agaggtatta cagatggcta ttatcttacc
   111361 agaacttcca tatgcatacg acgctttgga accatacatc gatgcggaaa caatgcattt
   111421 gcaccatgac aaacaccatc aaacttatgt caacaatgcc aatgcagctt tagaaaaaca
   111481 ccctgaaatc ggtgaagacc ttgaagcctt gcttgctgat gtagaatcta tcccagctga
   111541 tatccgtcaa gcacttatca acaatggtgg cggacacttg aaccacgctc ttttctggga
   111601 attgatgact cccgagaaaa cagctccttc agcagaactg gcagcagcaa tcgatgcaac
   111661 atttggttca tttgaagaat tccaagcagc cttcactgca gcagcaacaa ctcgttttgg
   111721 ttcaggttgg gcatggttgg ttgtcaacaa agaagggaaa cttgaagtga cttcaacagc
   111781 aaaccaagac acaccaatct cagaaggtaa aaaaccaatc ttgggcttgg acgtttggga
   111841 acatgcttac tacgtgaaat accgcaacgt gcgtcctgac tacatcaaag ctttcttttc
   111901 agtaatcaac tggaataaag tagatgaatt gtacgcagct gctaaataat gatagttgga
   111961 gggaagaatt gttcttctct tttttaggtt ataagattct ggtctgacaa aatcgttaga
   112021 cttttttcat tttttatgag aaacgtgcta actgctagaa attatggtag aataaagtat
   112081 taagtaatcg tggaaaaagg atatctatgc gaaaagaaat tgcacctgaa ttatacaact
   112141 ataacaagtt tcctggtccg gagttccatt tacacgggga caaggtcgaa acggaaggga
   112201 tagctttttc cttggttgaa aatatcaagg atgcctttga tgtgacgact tttaatcagc
   112261 gtttttcaga agtcttaacc aagtttgatt atatcgtggg ggactggagc aacgaacagc
   112321 ttcgcctacg aggtttttac aaggatgacc gaacagaaga aaaacttgaa aaaatcagtc
   112381 gtttacaaga ctacctttta gagtattgta gttatggttg tgcctatttt gtcttagaaa
   112441 atgaagcccc taagcgagca tcatttgaca agaaaatgcg taagacggaa gaagaaacac
   112501 cttctagaaa aggaaagaaa ccgactcaaa ctaaacgaaa gtcgaatgca gataagaaaa
   112561 atagacgtcg tcagaaagac cagcattctc agaaagagga caaggaacaa cgtcattttg
   112621 tcattcgtca gaagtgagta gagaataagg agaagaaatg aaaccctcaa ttcatagttt
   112681 ggtacatcaa accatgcagg aatgggtatt ggagcaggga gaaaagaaat tccgtgcaga
   112741 tcaaatctgg gaatggctct accgtaaacg tgtgcagtca tttgaagaaa tgaccaacct
   112801 ttccaaggat ttgattgcta agctcaatga ccagtttgtg gtcaatccct tgaaacaacg
   112861 tattgtgcaa gagtctgctg atggtacagt caaatatctc tttgaattgc ctgacggtat
   112921 gttaattgag actgtactca tgcgtcaaca ctatggttta tctgtctgtg tgaccactca
   112981 ggtcggctgt aatatcggtt gtaccttctg tgcctctggt ttgattaaga agcagcgtga
   113041 cctcaataac ggtgaaatcg tagcgcaaat catgctggtt cagaaatact ttgctgatga
   113101 aggggttcag gtcaatcttg ccgtgtctct tcacgcaccc aacaatgaac ttcgttcaag
   113161 tatcatgaag attaaccgtg cctttccgat tgaaaaactc tttgctgcta ttgaatacta
   113221 cattgagaca acaaaccgtc gtgtaacctt tgaatatatc atgcttaatg aagtcaacga
   113281 cggtgtagaa caagccttgg aattggctga attgctcaag aacatcaaga aattgtctta
   113341 tgtaaacttg attccttata acccagttag tgagcatgac caatatagcc gtagtcccaa
   113401 agagcgcgtg ttggctttct atgatacgct taagaaaaaa ggggtcaact gtgtggttcg
   113461 tcaagagcat ggtacagata ttgacgcagc ttgtggacaa ttgcgctcta acacaatgaa
   113521 acgtgaccgc cagaaggcag tcgcagcggt aaatccttaa tgatgaagaa gacttataat
   113581 catattttgg tctggggagt cattttctat agcatttgca ttgtctgttt ttgctttact
   113641 cctcaagaac aatctaccgt gggagtggga actccaggta ttcagcatct tggacgcctg
   113701 gtttttcttt tgactccttt caattctctc tggaaactgg gcgaagtgag tgacattgga
   113761 caattatgtt ggattttttt acaaaatgtc ctcaatgtct tcttgttttt tcctctgatt
   113821 ttccaactcc tttatctatt tccaaatttg cggaaaacaa aaaaggtcct tctttttagt
   113881 tttcttgtga gtcttggaat cgagtgtacg caattaatct tggacttttt ctttgatttc
   113941 aatcgcgtct ttgagattga tgatttgtgg accaatactt tgggtggcta tctggcttgg
   114001 ctcctttata aacgattaca taaaaacaag ataaggaatt aaaatgagta ttttagaagt
   114061 taaaaatctg agtcacggtt ttggtgaccg tgcaattttt gaagatgtgt ccttccgtct
   114121 cctcaaggga gaacatatcg gcctggtcgg tgccaatggt gaaggaaaat caacctttat
   114181 gagtatcgtg actggtaaaa tgctgccaga tgaaggaaag gttgagtggt ccaaatatgt
   114241 gacggctggt tacttggatc agcactctgt ccttgctgaa agacagtcgg tgcgtgatgt
   114301 tctccgtacg gcttttgatg agcttttcaa agctgaagct cgtatcaatg acctctatat
   114361 gaaaatggct gaagacggcg cggatgttga tgctctcatg gaagaagtag gagaacttca
   114421 agaccgtctg gagagtcgtg atttctatac cttggatgct aagattgacg aagtagcgcg
   114481 tgctcttggt gttatggact ttggcatgga tacggatgta acttctttgt caggtgggca
   114541 aagaaccaag gtgcttttgg caaaacttct ccttgaaaag cctgatatct tgctgttgga
   114601 cgagccgacc aactacttgg atgctgagca tattgattgg ctcaagcgct atctccaaaa
   114661 ctatgagaat gcctttgttc tcatttcgca cgatattcca ttcctcaatg acgttattaa
   114721 tattgtctat catgtggaaa atcaacagct gacgcgttac tctggtgact actaccagtt
   114781 ccaagaagtt tatgctatga agaaatctca gctagaggca gcctacgaac gccagcagaa
   114841 agagattgca gacctcaagg actttgtggc tcgtaataaa gcccgtgttg caactcgtaa
   114901 tatggctatg tctcgtcaaa agaaattgga taagatggat attatcgaac tccaaagtga
   114961 gaaaccaaaa ccatcctttg atttcaaacc agctcgtaca ccagggcgct ttatcttcca
   115021 agccaagaac ttgcaaattg gttacgaccg tcctcttact aagcctttaa atcttacctt
   115081 cgaacgcaat caaaaggttg cgattattgg tgctaatggt attggaaaaa caactctctt
   115141 gaagagtctc ttgggcatta tctcgccaat cgctggggaa gtggagcgtg gagattattt
   115201 agaacttggt tattttgagc aggaagtaga aggtggtaat cgccaaactc ctcttgaagc
   115261 tgtctggaat gcctttcctg cccttaatca agcagaagtc cgtgcagccc ttgcccgttg
   115321 tggtttgaca accaaacata ttgaaagcca gattcaagta ttatcagggg gagagcaagc
   115381 caaggttcgt ttctgtctct tgatgaatcg tgaaaacaac gttttagtgc tggacgagcc
   115441 gaccaaccat ttggatgtgg atgcaaagga tgagctcaaa cgcgctctca aagaatacag
   115501 gggatctatc cttatggtct gccacgagcc agacttttat gaaggttgga tagaccaaat
   115561 atgggatttt aataatttaa cttaagaatg agagtaaaag aaatacggct ctttgtcaac
   115621 tgtagtgggt tgaagtcagc taagctcgag aaaggacaaa attcgtcctt tcttttttga
   115681 tgttcagagc gataaaaatc ctttttttga agttttcaaa gtttcgaaaa ccaaaggcat
   115741 tgcgtttgat aagtttgatg agattattgg tcgcttccaa tttggcgttt gaatagggta
   115801 gttgaagggc gttgacgatt ttctctttgt tctttagaaa ggttttaaag acagtctgaa
   115861 aaataggatg aacctgcttc agattgtcct caatgagtcc gaaaaatttc tcagggtctt
   115921 tgttctgaaa gtgaaaaagt aagagttgat agatctgata gtggtgtttc aagtcttctg
   115981 aatagcttaa aatcttgtca agaatttctt tatttgttaa gtgcatgcga aaagtagggc
   116041 gataaaaacg tttatcgctg agtttacgac tatcctgttg gatgagtttc cagtaacgct
   116101 tgatagcctt gtattcatga gattttcgtt caaactgatt cataatttga acacgaaaac
   116161 gactcatggc acggctgaga tgttggataa tatggaaacg atctagaacg attttagcac
   116221 acggaaaaag ctgtttagcc aagtcatagt aaggactaaa catatccatc gtaatgattt
   116281 tcacttgaca acgaacggct ctatcgtagc gaagaaagtg atttcggatg acagcttgtg
   116341 ttctgccttc aagaacagtg ataatattaa gattatcaaa atcttgcgca atgaaactca
   116401 tctttccctt agtgaaggca tactcatccc aagacataat ctttggaagc cgagaaaaat
   116461 catgctcaaa gtgaaagtca ttgagcttgc gaatgacagt tgaagttgaa atggccagct
   116521 gatgggcaat atcagtcata gaaatttttt caattaactt ttgagcaatt ttttggttga
   116581 tgatacgagg gatttggtga tttttcttta ccaggggagt ctcagcaacc atcatttttg
   116641 aacagtgata gcacttgaaa cggcgttttc taaggagaat tctagaaggc ataccagttg
   116701 tttcgaggta agggatctta gacggttttt gaaagtcata tttcttcatt agacttccac
   116761 aatcagggca agatggagcc tcataatcca gcttagcgat aatttctttg tgggtatcca
   116821 tattgatgat atctagaatc ttgatgtttg ggtctttaat atcgagcagt tttgtgataa
   116881 aatgtaattg ttccatatga atctttctaa tgagttgttt tgtcgctttt cattataggt
   116941 catatgggac tttttttcta caataaaata ggctccataa tatctatagt ggatttaccc
   117001 actatagata ttatagagcc agaaatacag taccgaatgt ggatactgta tttttttggt
   117061 ttttaagatt taaaatcgta gtctttcacc acttcgatgc tgtcgattgt gatagcagta
   117121 gttggcttgt ctttttcatc tttttcggct ttagcaatct tatccacaac atccataccg
   117181 tcaatcactt gaccaaagac tgggtgtttg ccatctagac tagggtttcc accttctttg
   117241 taggcttcga taattttctg tggatacttg cttgtaggga gtttagaaga ggtatctgta
   117301 gagttttggt tgatgaagaa ctggctgcca ttggtgtttg gttgaccagt attagccata
   117361 gcaagagcac cacggatgtt atacaaataa ggagtaatct cgttcttgaa accagttcct
   117421 ttgtctttag tcttatcctt gtcatgccat atggactgac cacctgtacc gtcccctttt
   117481 ggatctccag tttggaccat aaagccatcg atgacacggt ggaaggtaat accgttatag
   117541 tagccttctt tggcgtgagt gaggaaattt tcaaccgcta gaggagcgag tttagggaag
   117601 agtttaatgc gaatatcacc ttggcttgtg tggagaatca cttcggcttc atcttcagca
   117661 acttccttag atagttgtgg gaaattggcg ttttcgtttg ttaaagcatc gtttaactcc
   117721 ttggcagatt gggcagctac tttggaactt tcttcagcag caagactgga atcaacataa
   117781 tcatcaccac gcagactgcg ttggacgctg ctacacccag ctagggctac agtagacagt
   117841 aaaagaaggg ttgctagttt tttcattctg atcctctcaa aaattcattt ataaccattg
   117901 taccctaaaa ggaagtggat ttcaaatatt agtagtttac agaactggct tagataatag
   117961 ttgggatttc atcatcatct tgaaaatctt caacttcttc aacttcttcc ccagtaaatg
   118021 gtttctgaaa agaacttagt ataaaacggg caattggttc aacaattagg aaatttagag
   118081 gaagagctgc aataaagttt acgaaccagg cgcttagata ggtattgggt gtgatagcaa
   118141 tgccattgta aaaaagtcca tagaaggaca tgaaagtgac cagctaattc ttcttctgaa
   118201 aaatgctcat gaagggcttg atccaggtcg caagatttca ttttagaaag tccagtaact
   118261 cccttcttct tcaggatatt ctttttcatg gtagtattta gatggtcaag tgagtcaaaa
   118321 gaagtttcga caagagcata ccctttttct accagagttt ttagatgttt aggggcatca
   118381 ataccataag tgtactcaaa gtattttgga aaccagatct taagaaagct cgtaaagcta
   118441 gccagttctc taaacgctaa gaactagcta caacacagca tttacaacac ttcatggttc
   118501 acaccatggg gtgtttttta atgattttaa gcaaaattca cacttaattg aaagttattt
   118561 aaattagatg aaaatttatt ttttgaaaaa gtgggaaaac attgattcta agcgaatttt
   118621 gaatcatatt cgaatgggag tttttaaaat catgtttcag tggtaaaagt accaaactgg
   118681 attctccata gtaaaatgat atctcctgct agtgaatcat ctactaataa gtccatattt
   118741 cgcttgggaa cgggcttggg acttagaagc caagtatcca actctcgttc aggcgatatg
   118801 aagggtttga cttggtgttc tttataaaat ttttctaaaa tagtattcac ggatagcatc
   118861 tttcaaacat ttatttccta ttctaacaaa tttctaaata ctttaagaaa tttatagtct
   118921 gtcaagtttt tttcttgaca catgccagaa atctgctata atagaacatg tgctagatag
   118981 ctcagctatt tcaccgaaat aaaaaattaa agaaatgaga ctttaaaaat ggcagttaaa
   119041 atccgtttga ctcgtatggg ttctaagaaa aaacctttct accgtatcaa cgtagcagat
   119101 tcacgttcac cacgtgacgg acgtttcatc gaaacagttg gaacttacaa cccacttgtt
   119161 gctgaaaacc aagtaacttt gaaagaagac cgcgttcttg catggttggc taatggagct
   119221 caaccttcag acacagtacg taacatcctt tcaaaagaag gcgtattgaa aaaattccac
   119281 gattctaaat tttcaaaata agtttaaagt aggttgacag atggatacga ttgaaaatct
   119341 cattattgcg attgtgaaac ccttaatttc acaaccagat gccttaacta tcaagattga
   119401 ggatacacca gaatttttgg aatatcattt gaatcttgat caaagcgatg tgggtcgtgt
   119461 aatcggtcgt aagggtcgca ctatttctgc gataagaacg attgtctact ctgtcccaac
   119521 tgaatacaaa aaagtaagaa tcgttattga cgaaaaataa gaagggcggg acggatgtct
   119581 cgcttttttg tgtggaatag aagatatagt aaaatgaaat aataacagga caaatcgatc
   119641 aggacagtca aatcgatttc taacaatgtt ttagaagtaa aggtgtacta ttctagtttc
   119701 aatatactat aaaagattga acgtttaggc aattccaaga ctacttactc gaacattaac
   119761 agcagtctcg gactgatgaa ggtctcttta tgaagttagt ggagaagtag ccgaggtttt
   119821 gaataggcgc tctggtcgaa aagaagggat aggattcgaa cgaggaactt gccagagaac
   119881 tggctgatat catttactac accgtcgcaa tcgtagctat taatcatatt gaccttacca
   119941 agactgtctt tgagaaagac aaaaccgcag ccgttaatta ccaacataaa catgatttgg
   120001 aaggattttt gaagggaaag tagagatgtt gtccccttcc tccaacttga gaaaatcctt
   120061 ggaacgtgat aaaataaaag ataaggattt ttaataattc attatataga atgagtggat
   120121 ttctttatga agaggtttga agtatctaca gaaattggta gcctctctgt tacttatcaa
   120181 aagcaaaaga aagtgctagt ttgtctaaac ggagcaggtt tgctaccaag ttatgaaaat
   120241 ttttcactta tacttgaaaa acctcctcct acaattggtt atttgacaat tgattttccg
   120301 aacacaggta ggagtccgat tcatgaccaa gctggaaaaa atctagataa tcttgcagat
   120361 gtggtttatg aagtacttga agaattaggg atttctgaat atatactttg tgcacatagt
   120421 tggagtggaa ttttagcttg caaattactc gagaaaccaa ttaagtgtca gactttagta
   120481 gcaattgaac cgacaactaa aaaagtcatg tttgctgatt tttcagaaaa tccttatcca
   120541 gaaatggaag agcagatgag gctgattgac gagtgtggtc ctgaacttta ttttaagaac
   120601 ttaactcaag caacatttag tcctgaaacg aataaaaaaa tctgggaatt aatgcaagaa
   120661 aaaggcttag agttggaaaa tcaagatcca gaatttcaga tatctggaga gattactgag
   120721 gaagattttg agaatttgtc gatagaatct catgtccctg tatttatttt ttgtcagact
   120781 tatagagaaa aagagtacag agaatcagaa tattggactt ctaatactaa actcatttta
   120841 ggagggaatc accattattt acaatggtca gaatcggaaa aaattgcggc tattattcga
   120901 gaattgtcag aataagatgg aaaaaaggag attacaggag acaagatgaa ctactttaat
   120961 gttgggaaaa tcgttaatac gcagggatta cagggtgaga tgcgagtctt gtctgtgacg
   121021 gattttgcag aagaacggtt taaaaaagga gctgagctgg ctttgtttga tgaaaaagat
   121081 cagtttgtcc aaacagtgac catcgctagc caccgtaaac agaagaactt tgacattatt
   121141 aaattcaaag atatgtacca tatcaatact atcgaaaagt acaagggata tagtctcaag
   121201 gtcgctgagg aagatttgaa tgacctagac gatggtgaat tttactatca cgagattatc
   121261 ggtttggaag tctatgaggg tgatagcttg gttggaacca tcaaggaaat cctgcaacca
   121321 ggtgctaatg atgtctgggt ggtcaaacga aaaggcaaac gtgatttgct tttaccttat
   121381 atcccaccag tggttctcaa tgttgatatt ccaaataaac gggtcgatgt ggaaatctta
   121441 gaagggttag acgatgaaga ttgatatttt aaccctcttt ccagagatgt tttctccact
   121501 ggagcactca atcgttggaa aggctcgaga aaaagggctc ttggatatcc agtatcataa
   121561 ttttcgagaa aatgctgaaa aggcccgtca tgtagatgat gagccctacg gaggcagtca
   121621 aggcatgttg ctcagagcac aacctatttt cgattccttt gatgctattg aaaagaaaaa
   121681 tccgcgcgtt attctcctcg atcctgctgg aaagcagttt gatcaggctt atgctgaaga
   121741 tttggctcaa gaggaagagc taatctttat ctgtgggcac tatgagggtt atgatgagcg
   121801 cattaagatc ttggtaacag atgagatttc cctaggcgac tatgtcctca ctggtggaga
   121861 attggcagct atgaccatga ttgatgctac agttcgcctg attccagaag tgattggcaa
   121921 ggagtctagc caccaagatg atagtttttc ttcaggtctt ttagaatatc ctcagtacac
   121981 acgtccctat gattatcgag gcatggtcgt gccagatgta ttgatgagtg gccaccatga
   122041 aaagattcgt cagtggcgat tgtacgagag tttaaagaaa acctacgagc gcagaccaga
   122101 tttacttgaa cattatcaac tgacagtaga agaagaaaaa atgctggcag aaatcaaaga
   122161 aaacaaagaa taaaggagaa acctatgcaa gtaatcaaac gtaatggcga aattgctgaa
   122221 tttaatccag ataagattta ccaagccatc ttgaaggcag cccaaactgt ttatgttttg
   122281 acagatgatt tgcgtcaaaa tcttgctcaa gtcactaaga aggtagtttt ggatttacaa
   122341 gaagccaagg tggaacgtgc gactatcagt atgattcaat ctatggttga acatcgttta
   122401 ttgggcgcag gttacattac cattgcagaa cactacattt cctatcgttt acaacgtgac
   122461 ttggaaagaa gtggttatgg agatcatatt gcagttcatt tacattttga acaaattcgc
   122521 taagaaaaaa gagtgggatg aagcaactac atctcactct ttcttaaatc tatttttttg
   122581 ggctgtttgg acagttgagg ggacaaatcg caggcgttga atatcgctta tacggataat
   122641 ccggctcaca tttttggcaa aatttttcac gataatttgc tggccttgct gatcatattt
   122701 gatgatatca cctgtaaaac ttgtctcaga caagataagg tgaacagcgg tttgtttctg
   122761 gatagcctct tcaatagtgg ctgtaaggga gttggtttca gtctggtcag gttggtcatg
   122821 tccatttaaa aaatcatgta ttttatctag aacttgctgg aatttatgtc tcatattggc
   122881 ctcccttctt ttatatcaat attatataaa attttcctaa aatctacaag attttacgaa
   122941 taaactaatg aaactaaaaa aggagaagaa aatggcagaa tttacatttg aaatcgaaga
   123001 gcacttgttg actctttctg aaaacgaaaa aggttggacc aaggaaatta accgtgtgag
   123061 ctttaatggt gcccctgcaa agtttgatat tcgtgcttgg agtccagacc atactaaaat
   123121 gggcaaaggg attactctct caaatgaaga atttcaaacg atggtggatg cctttaaagg
   123181 caactaatac tcttcgaaaa tctcttcaaa ccgcatcagc tttgccttgc cgtatgtatg
   123241 gttactgact tcgtcagttt catccacaac ctcaaaacag tgttttgagc agcctgcggc
   123301 tagcttccta gtttgctctt tgattttcat tgagtataag ttttcaaaat aaaaaaaagg
   123361 atattgagtc atgataactc ggtatccttt tttagttagt aaagtaagcc tgatttttaa
   123421 ggcgttgaag taggggacgg ctaataaaac taatagccag aagtttgcca aggtctggaa
   123481 tgataaaggg aagaaccccc acaacaagag ctttttcaaa tgccattcca gctaggaaat
   123541 gcaagctgag aatcccgccg acaaagacaa gggcatcacc caagaggttt gcaagaaaaa
   123601 tcttaacaac accactcttg ctgttggtta gagaggaagt aagtccagag taaacgagat
   123661 aaaaccaaag atagcctgca gtagggccaa ctaaagcctg aaaaccagct ccacctcctg
   123721 caaagacagg aagaccgata gcacctagaa gaagatagag tccagcagaa agtacagcct
   123781 ctctcggtct aaagacagta gcaatcaagc cgattgcaaa gttttgcaga gtgaagggaa
   123841 caggtccaat tggaagactg atttgtgcca aaacagcaat gagagcagcc ccaatagcag
   123901 ggatagcata aacgtgagct tttttcaaaa tagttaacct cttttctaat gtatagtaac
   123961 tattatactc atataggagt cgatgtcaac cattttttaa aaacaaggta acaaaaactg
   124021 taacagccga ttttcgtgac tagtcaagtt ggataatttt tttgttgatt cgaaaattgt
   124081 ctgtatagat aatcctattt tattaataaa aaatatacta gtaaatactt gacaaattaa
   124141 aaaataagtg ttacattaaa aatgtaaacg gatacattta gatgtgttca attttaaaag
   124201 gaggggtagt tatgagatat tttaacgact ctagatacca taacggtgat taaaaaccta
   124261 aatataatca attcatatta aagtaatatg gagggactaa aaagagacta ttatttaatc
   124321 ttcatcaaat atttaaattc aaggagaagt aaaatgaaaa aaagaattaa taagaaagca
   124381 tctgtttttc tagttgcaag tgttttcagt tttagctttg ctactacagc tagtgtcgtt
   124441 aacgcagtaa cggcacaccc tgctccaagt cccattattg atgtatggga atatggtgta
   124501 aatgataact atggttattc gaattacttt gttagttctc caagtaatat tggatcaaaa
   124561 tcttcagtaa cgaatttttg gggaacagtt aaagctcagg ataaaaaaga ttatggatgg
   124621 gcatattcaa gtgcaacaaa atcttggaac gatgttcgct taaatgcata ttgggattat
   124681 tatagatttt aaaaataatt tatgaaaaca agagacccaa ttataagatt gggtctcttg
   124741 taatatggta attgcttatg aaattaaaat tatgtatcat tggattcttc ttttgtttga
   124801 ttgctacaat tggtctggtc actattagtg ataccgaaat ccccatacct ttaccaattg
   124861 atggagcttt ttctatccaa ggaaaaagta atctttctaa taacgaaata tacgaaatgg
   124921 ttcgtgactt atcaaaaacg gaaaaggtta ccatttacaa gccaatcgtt cagagttcgg
   124981 gtcagttgaa gtatgtaaat tttgatgatg taaataatga acaattaaag tcagcaccaa
   125041 tagtagggat gtattacaca cttgggaaaa tggatgtaga cagtttgaaa ccacttacga
   125101 tgacgggact acaaacagtc tatatggctt atccttggta tataggagga atattacaat
   125161 tcactggaac tttaagaata ctgttaatgg gttcaattta tttaacttta ttagttgttt
   125221 tatttgttgt taggacgagg cagatcaaag aaggagtgat acgacgttct ttgggcttgc
   125281 ctatatacga cttaagaaga gagtatggca tttctcttat ttttgaactg attatgatgg
   125341 ctttattgat gatttcttac agttcttttt tgggtaatgg tttcttcacc tatagttcta
   125401 agttattttt ctctctgctt ttaacgaatt ttatactatt tcaaatcatt gatcttatta
   125461 cttttgtttt attttggttg acgattcaga ttgaaaagcc tattgaaatt attaaaaaca
   125521 aggcaaaaaa caagcttatt tttgtcgtat ggcttgctat tatttcgatt atcatccttg
   125581 tctcaggagt ttttttacaa gaaacaaaga gtagtcaatc tagtattaac atacagatac
   125641 agaatttagt accatgggat acagtaaaag actggagaag gattgagttc cttggaattg
   125701 aaagtaactc tactaaaaat agagaagtta atgattcaga tggtcagtat ctacagatag
   125761 ttgctgcctt aaaaaactta gatttcttat atatagaacg gtcttcagca tatgttccag
   125821 atttcatgaa aacttcacat gttatagaaa atttttctaa acaattagaa aatgacggga
   125881 taacgaatcc agaaataaat aaagagttaa tttatatcaa ccaaacaggt gctaacctac
   125941 aaaataaagt gaatggaaca aactatcatc ttttagataa taagatagca accatctata
   126001 ttcctgagaa gtggaaagaa aaccagaaat ctattgagaa tacagttgta gcagaacaat
   126061 ttattggaac aaactataca agagaacagc ttgcagttca aataattcct gatggggaaa
   126121 aaatttttta ttttaatgag gatgctgata ataatcttaa aatgaaagat attttaccgc
   126181 tggcaaatgt agcagatagc aaagataata tagttgttgt gttagatacg gacaaaatga
   126241 tggaaaataa taagttttct ttggctagta acatactata taaatctctt tttagtcctg
   126301 aagcggtaaa aaaaataaat gagatgactg tcctgttgaa tttctcaatg aatccagtag
   126361 atgtttacca aattgtgaaa ttaaagattc aatccttaga gcaccaaatt ttactttcac
   126421 aaatcttgca gaagataatt tacagtattg tctttatact catttatcaa tatgtccaac
   126481 tttttattac tctaaaacag aatgaatatg tgaaaaaaat cattttgggt ctgtcaaaaa
   126541 catatatagc aatttcaagt ctcaaatatt ttatgatgac tattacaatg gttattctat
   126601 ttacatttct tatgacaggg caaatagagt tgctatatat tggagcggct tctctgctag
   126661 ttttgatgtt gtcaatcata atgagtttta gaaaattatc tgaaagctac actaaaattt
   126721 taaaaggaga tgaatcatga caattgacct tttgaacgtt tcaaaaagtt tcggctcaaa
   126781 gaagatcttt acagacttaa atttaatatt tgaatctgga aaaagctatg cattgattgg
   126841 aggttctggc tccggtaaaa gtacccttct taatattata ggaagattag aaaaaattga
   126901 cagtgggaat gttttagttg ataaacaaga tatttggaag ataaaagaaa gaactttttt
   126961 taaaaatact gttggatatg tatttcagaa ttattcttta atagataaca aaacagtgta
   127021 tgataatctg agccttatca ctaaagacaa aaaaacaata actgacgtac ttgaaaaagt
   127081 aggactgtca agtgactatt tacaccaaaa aatatatgaa ttgtctggag ggcaggctca
   127141 acgtgtagct attgccagaa tgttaatgaa accacgtaaa attatcttag cagatgaacc
   127201 tacaggagct ttagatggtg agattggaaa agaaattatt cgtttactat tgaatgaaac
   127261 agctgaagat aaatatgtca ttatagcgac acatgatcca gctgtctata acgaagttga
   127321 tgtgataatt gacatgaaag atatagggta taaggtatga aaaagaaaat ttatattgct
   127381 ttgatctttg taactggggt actcgccatt ttcttttttg gaaaacaaat gattacaaaa
   127441 gaaaatatca ataagccaac ggtagagtta acaatctata cgctttcttc tagtgataca
   127501 gaaaaatgga ataaagtgag acaagtagaa acggaagaag ctatatactt cataactgtg
   127561 aaagaagtat catcttcaga agaagtattt tcaaacatca ttgcaaatgg agctgctacg
   127621 gggttcggag ttcgtgaaga agaagtgaag aaattcaata atggtttagg agacaccata
   127681 gaggactcta agcataataa actaattgaa atagaatttt ttactttttc tgatgatggc
   127741 gcgggatttg tggtagcaaa ctttgactac ggtaaagaag agttgaattc tcagaaaaaa
   127801 gatataaaag aattatataa aaaaatatat gaatctttta aagaaaagaa taaatgattg
   127861 tattataatc cttgtatttt gctatggttt gttaattgat ttttgcatat cttacttcaa
   127921 catactataa aataaaacat aagaaaacga gtatctccaa ctacggaaat actcgctttt
   127981 tgatatttag aagtgttttt tgctttgctt cttttgtttc gattaacgca tggttacaaa
   128041 ttcttcagat gcagttgggt gaattgccac agttgcatca aagtcagcct tggttgctcc
   128101 cattttgata gcaacggcaa atccttgaat catttcatca acgccgtagc caattccatg
   128161 aagtccgaca actttttctt ctgaaccagc tgttatgagt ttgaaacggg attcttgacg
   128221 gttgcgagtg caagcagagt acatagatgc aaagcttgat ttataaacct tgatttggtc
   128281 ttgaccgtat tctttaatag cttgctcttc tgtcaaacca acagttccga tagcagggtg
   128341 tgaaaagaca acagttggaa tagttgagta atccattttt gcagtagttt ttccgttaaa
   128401 gagacgttca gatagggtac gtccggcctt gattgcaact ggagtcagtt ctttctcgcc
   128461 cgttacatca cctagagcat agattccctc aacaacagta ttttggtatt catccacttg
   128521 gataaagcca cgttcgttca gagtcactcc agctttttca agttgcaagc ccttaacgtt
   128581 tggacggcga cctgtagccc agataacttg gctagctgtg tgactagtac catcttcgaa
   128641 atgaatggta atgccgtcag tagttttttc taacttgaca gggactttgt gagtgtgaag
   128701 tggtaagttt gttctttcca tttccttgac caaaccttca acgatgtagg aatcaaaacc
   128761 acgtaaagga cgatcgcggc gaacaaagag atctgtcttg acaccaaaag tgtggagtac
   128821 gccagctaat tcaacggcga tataaccagc gcctagaatg gcaattgact ctggaagttc
   128881 ttcccaggca aatacatcat cagaagagcc acctagctca gcaccaggaa tattaggaat
   128941 acttggatgg gcacctgtag caatcacgat atgtttagca cgaatcagtt caccatttac
   129001 gcttacagta tgagaatcta caaattcagc atgaccttca atcaagtcta caccgttgcg
   129061 tttaaaacta ccatcataag aagaacgagc gcgatcaatg taggcttcac gattgcgacg
   129121 tagggttgca aagtcaaagt taagatcagt agtcttaaag ccgtagtctt ctccaaattg
   129181 atggaaagtc tcagcgattt gcgccccgta ccacatgatt tttttaggaa cacaaccgac
   129241 gttgacacag gttccaccta atttcttttc ctcaataacg gctgctttgg ctccatgttc
   129301 accagcacgg ttcatggtag cgattcctcc gctacctcca ccgatagcaa tgatatcata
   129361 ttctctcatt gaaaactcct ttgtaatctt ttaaatagta gagcgtcttt tttgatagtt
   129421 atattttatt ctttttttga tttgattgca aaaatctgct acgcacaaaa aattgcaaaa
   129481 aagcttgcca aataagtcaa gatagtgtat tatatatcta gtacaataga aaagcaaaat
   129541 tccgaacgat tgtttaatcc tgaactgtat tgtttgctgg agggaaattt ggtataatag
   129601 caaagtattg taaaaaagaa aaggagtttc attatgaaga aaaagaatgg taaagctaaa
   129661 aagtggcaac tgtatgcagc aatcggtgct gcgagtgtag ttgtattggg tgctgggggg
   129721 attttactct ttagacaacc ttctcagact gctctaaaag atgagcctac tcatcttgtt
   129781 gttgccaagg aaggaagcgt ggcctcctct gttttattgt cagggacagt aacagcaaaa
   129841 aatgaacaat atgtttattt tgatgctagt aagggtgatt tagatgaaat ccttgtttct
   129901 gtgggcgata aggtcagcga agggcaggct ttagtcaagt acagtagttc agaagcgcag
   129961 gcggcctatg attcagctag tcgagcagta gctaaggcag atcgtcatat caatgaactc
   130021 aatcaagcac gaaatgaagc cgcttcagct ccggctccac agttaccagc gccagtagga
   130081 ggagaagatg caacggtgca aagcccaact ccagtggctg gaaattctgt tgcttctatt
   130141 gacgctcaat tgggtgatgc ccgtgatgcg cgtgcagatg ctgcagcgca attaagcaag
   130201 gctcaaagtc aattggatgc aacaactgtt ctcagtaccc tagagggaac tgtagtcgaa
   130261 gtcaatagca atgtttctaa atctccaaca ggggcgagcc aagttatggt tcatattgtc
   130321 agcaatgaaa atttacaagt caagggagaa ttgtctgagt acaatctagc caacctttct
   130381 gtaggtcaag aagtaagctt tacttctaaa gtgtatcctg ataaaaaatg gactgggaaa
   130441 ttaagctata tttctgacta tcctaaaaac aatggtgaag cagctagtcc agcagccggg
   130501 aataatacag gttctaaata cccttatact attgatgtga caggcgaggt tggtgatttg
   130561 aaacagggtt tttctgtcaa cattgaggtt aaaagcaaaa ctaaggctat tcttgttcct
   130621 gttagcagtc tagtaatgga tgatagtaaa aattatgtct ggattgtgga tgaacaacaa
   130681 aaggctaaaa aagttgaggt ttcattggga aatgctgacg cagaaaatca agaaatcact
   130741 tctggtttaa cgaatggtgc taaggtcatc agtaatccaa catcttcctt ggaagaagga
   130801 aaagaggtga aggctgatga agcaactaat tagtctaaaa aatatcttca gaagctaccg
   130861 taatggtgac caagaactgc aggttctcaa aaatatcaat ctagaagtga atgagggtga
   130921 atttgtagcc atcatgggac catctgggtc tggtaagtcc actctgatga atacgattgg
   130981 catgttggat acaccaacca gtggagaata ttatcttgaa ggtcaagaag tggctgggct
   131041 tggtgaaaaa caactggcta aggtccgtaa ccaacaaatc ggttttgtct ttcagcagtt
   131101 ctttcttcta tcgaagctca atgctctgca aaatgtagaa ttgcccttga tttacgcagg
   131161 agtttcgtct tcaaaacgtc gcaagttggc tgaggaatat ttagacaagg ttgaattgac
   131221 agaacgtagt caccatttac cttcagaatt atctggtggt caaaagcaac gtgtagccat
   131281 tgcgcgtgcc ttggtaaaca atccttctat tatcctagcg gatgaaccga caggagcctt
   131341 ggataccaaa acaggtaacc aaattatgca attattggtt gatttgaata aagaaggaaa
   131401 aaccattatc atggtaacgc atgagcctga gattgctgcc tatgctaaac gtcagattgt
   131461 cattcgggat ggggtcattt cgtctgacag tgctcagtta ggaaaggagg aaaactaaga
   131521 tgcagaatct gaaatttgcc ttttcatcta tcatggctca caagatgcgt tctttgctta
   131581 ctatgattgg gattattatc ggtgtttcat cagttgttgt gattatggct ttgggtgatt
   131641 ccctatctcg tcaagtcaat aaagatatga ctaaatctca gaaaaatatt agcgtctttt
   131701 tctctcctaa aaaaagtaaa gatggttctt ttactcagaa acaatcatct tttacggttt
   131761 ctggaaagga agaggaaatt cctgttgaac cgccaaaacc gcaagaatcc tgggtccaag
   131821 aggcagctaa actgaaggga gtggatagtt actatgtaac caattcaacg aatgccatct
   131881 tgacctatca agataaaaag gttgagaatg ctaatttgac aggtggaaac agaacttaca
   131941 tggacgctgt taagaatgaa attattgcag gtcgtagtct gagagagcaa gatttcaaag
   132001 agtttgcaag tgttattttg ctagatgagg aattgtccat tagtttattt gaatctcctc
   132061 aagaggctat taacaaggtt gtagaagtca atggatttag ttaccgggtc attggggttt
   132121 atactagtcc ggaggctaaa aggtcaaaaa tatatgggtt tggtggcttg cctattacta
   132181 ccaatatctc ccttgctgcg aattttaata tagatgaaat agctagtatt gtctttcgag
   132241 tgaatgatac cagtttaacc ccaactctgg gtccagaact ggcacgaaaa atgacagagc
   132301 ttgcaggctt acaacaggga gaataccagg tggcagatga gtccgttgta tttgcagaaa
   132361 ttcaacaatc gtttagtttt atgacgacga ttattagttc catcgcaggg atttctctct
   132421 ttgttggagg aactggtgtc atgaacatca tgctggtttc ggtgacagag cgcactcgtg
   132481 agattggtct tcgtaaggct ttgggcgcaa cacgtgccaa tattttaatt cagtttttga
   132541 ttgaatccat gattttgacc ttgttaggtg gcttaattgg cttgacaatt gcaagtggtt
   132601 taactgcctt agcaggtttg ttactgcaag gtttaataga aggtatagaa gttggagtat
   132661 caatcccagt tgccctattt agtcttgcag tttcggctag tgttggtatg atttttggag
   132721 tcttgccagc caacaaggca tcgaaacttg atccaattga agcccttcgt tatgaatgag
   132781 atcaacaaga tggacactcg tctatcttgt ttttgtatgg atttccctat cgaaattcat
   132841 taaaaatgtg atataatgaa gtgttagaaa aacaggtttc atttgcctgg aaaggaaaaa
   132901 ttatgtctga aaaaaatttt tatattacaa cgccgattta ctatccatct gggaaacttc
   132961 atatcggttc tgcctacaca actatcgcat gtgatgtcct agcacgttac aaacgcctga
   133021 tgggctacga tgtattttat ctgacaggtc ttgatgaaca tggtcagaaa atccagcaga
   133081 aagcggaaga agctggtatt acacctcaag cctatgttga tggaatggcg gttggagtta
   133141 aagaactctg gcaattacta gatatctcat acgataaatt tatccgtaca actgatgact
   133201 accatgaaaa agttgtcgca caagtctttg aacgcttact tgctcaagat gatatctact
   133261 tgggtgaata ctctggttgg tattcagtat cagacgaaga attctttaca gaaagccagc
   133321 tggcagaagt tttccgtgat gaagctggaa atgtgactgg tggtattgct ccatcaggtc
   133381 atgaggttga atgggtttct gaagaatcat acttccttcg ccttagcaaa taccaagacc
   133441 gtttggtcga atttttcaaa gctcatcctg aatttatcac gccagatggt cgccttaatg
   133501 aaatgctacg caacttcatc gagccaggtt tggaagattt ggcggtatct cgtacaacct
   133561 ttacatgggg agtgcctgtc ccatcaaatc caaaacacgt tgtctacgtt tggattgatg
   133621 cccttcttaa ctatgcgaca gctcttggct acgctcaaga cgaacatggt aactttgaca
   133681 agttctggaa tggaacagtc ttccatatgg taggaaaaga tatccttcgc ttccactcta
   133741 tctactggcc aatccttctt atgatgttgg atgttaaatt acctgatcgt ttgattgccc
   133801 atggttggtt tgtcatgaaa gacggaaaaa tgtctaagtc aaaagggaat gtcgtttacc
   133861 ctgaaatgtt ggtagagcgt tatggactag atccacttcg ttactacctc atgcgtaacc
   133921 ttccagttgg ttcagacgga acctttactc ctgaagacta tgtcggccgt atcaactatg
   133981 aattggctaa tgaccttggg aacctcctta accgtacggt ttccatgatt aataagtact
   134041 ttgatggaca aatccctgcc tatgtagaag gtgtgactga atttgatcat gttcttgctg
   134101 aggttgcaga acaatcaatc gcagacttcc atacacacat ggaagcagtt gactatccac
   134161 gtgcgcttga agcagtctgg actctgatct ctcgtaccaa taaatacatc gatgagactg
   134221 caccatgggt cttggccaag gatgaagctc ttcgtgacca attggcaagt gtcatgagcc
   134281 acttggcagc cagcattcgt gtagttgctc acttgattga accatttatg atggaaacta
   134341 gtcgtgcagt tttgactcaa cttggtttgg aagaagtttc tagtcttgaa aacttgagtt
   134401 tggctgactt cccagcagat gtgactgtag ttgccaaagg aacacctatc tttccacgtc
   134461 taaatatgga agaagaaatc gcctatatca aggaacaaat ggaaggcaat aaaccagcag
   134521 tcgaaaaaga atggaatccg gacgaagttg agctcaaact aaacaaggat gaaatcaagt
   134581 ttgaagactt tgacaaggtt gaaatccgtg tcgcagaagt caaagaagtg tctaaagtag
   134641 aaggttcaga taagttgctt caattccgct tggatgctgg tgatggagaa gatcgtcaga
   134701 ttctttcagg aattgcaaaa tactatccaa atgaacaaga attggtcggc aagaaagttc
   134761 aaatcattgc taacctcaaa ccacgtaaaa tgatgaaaaa atatgtcagc cagggtatga
   134821 ttctctcagc tgaacatgat ggcaaattaa cccttctcac agttgatcca gctgtaccaa
   134881 atggaagtgt gattgggtaa aagtagacag gactagttca ggctagttct gtttttttat
   134941 ttatactcaa tgaaaatcaa agagcaaact aggaagctag ccgcaggttg ctcaaaacac
   135001 agttttgagg ttgtagatga aactgacgaa gtcagctcaa aacacagttt tgaggttgta
   135061 gatgaaactg acgaagtcag ctcaaagcac tgctttgagg ttgtagatga aactgacgaa
   135121 gtcagctcaa aacacagttt tgaggttgta gatgaaactg acgaagtcag taaccataca
   135181 taaggtaggg cgacgctgac gtggtttgaa gagattttcg aagagtatta actattatgc
   135241 tttacaaact agtgtagaag tgatatacta taggtgaagt tactagtagg tattacaaaa
   135301 tagattagaa gggaaaagtg atgaaagaaa ctcagctatt aaaaggtgtt cttgaaggtt
   135361 gtgtcttgga tatgattggt caaaaagagc ggtatggtta tgagttggtt cagactttgc
   135421 gagaggctgg atttgatact atcgttccag gaactattta tcctttgttg caaaagttag
   135481 aaaaaaatca atggataaga ggcgacatgc gcccgtcgcc agatggtcca gatcggaagt
   135541 atttttcatt aatgaaagaa ggagaagagc gtgtctcagt cttttggcaa caatgggacg
   135601 atttgagtca aaaagtagaa gggattaaga atgggggtta aaccatgaag aaaatgaagt
   135661 attacgaaga aacaagcgct ttgctacatg agttttctga ggagaatcaa aagtattttg
   135721 aggagttgtg ggaaagtttt aatcttgctg gatttctcta tgatgaagac tatctcagag
   135781 agcagatcta tttgatgatg ctagatttct cagaagcaga acgagatggc atgagtgcag
   135841 aggattatct aggtaagaat cctaaaaaaa taatgaaaga gattctcaag ggagcacctc
   135901 gcagttctat caaagagtcc cttttgacgc caattcttgt cctggcggta ttacgttatt
   135961 atcaactact aagtgatttt tctaaaggtc ctctcttaac agtcaatttg ctcacatttt
   136021 tagggcaact tcttattttt ctgattggat ttggacttgt ggccacaatt ttacgaagaa
   136081 gtttagtcca agattctcct aaaatgaaaa ttggcactta cattgttgtt gggactatag
   136141 ttcttctagt tgttttagga tatgtaggaa tggcaagctt catacaagaa ggagcctttt
   136201 atattccggc tccctgggat agtttgtctg tctttacgat ttcgctagtt atcggtattt
   136261 ggaattggaa agaagcggtc tttcgtccat ttgtcagtat gattattgcc catcttgtgg
   136321 tgggttctct gctccgttat tatgagtgga tgggaatttc aaatgttttc cttacaaaag
   136381 ttattccttt agctgtcctc tttattggca tttttgtctt gttccgtggg tttaagaaga
   136441 taaaatggag tgaagtatag tcaaaaagcc gttgcaaagc ggttttttgt tataatgaag
   136501 ggaagaatgt tagaaattaa aggagaaaaa tttgatgaga tacataactc ttggtcaaga
   136561 tgacaaagaa ttatcagaaa ttgttctcgg aatgatgaga ataaaagata agtctgtaaa
   136621 agaagttgaa gagcttgtag aaacagcact ttctgttgga atcaatgcct ttgacttggc
   136681 tgatatttat ggtcgtggtc gttgtgaaga actgttaggt cttgtcctaa aaaatcgtcc
   136741 agatttaaga gaaaagatgt ggattcagtc caaatgtggc attcgcattg aagaatttac
   136801 ctattttgat ttttctaagg actatattat aaaatcagta gacggtattt tgcaaagatt
   136861 gaagattgat catctagata gcttgctcct tcatcgacca gatgctttga tggaatctga
   136921 ccaagtagca gaagcctttg atctccttta taaacaaggt aaagttcgag attttggagt
   136981 ttctaatcaa aatcctatga tgatggagtt gcttaaaaaa gatgtcaagc agccgttagc
   137041 tgttaatcag ctacaattga gtgcggcttt tactccagga tttgaatcag cttttcatgt
   137101 taatatggaa gatagtcaag cagctatgcg agatggcagc atttttgaat attgccaatt
   137161 acacgatgtg gtcattcaag catggtctgt cttgcaattc gggtatttta aagggaactt
   137221 tgttggaaat gagaaatttc aagctttaaa tcaagtactt gatcgtttag ctattaaata
   137281 tggagtaacc tcttcaacta ttgccatttc ttggatattg cgttatccag caaaaatgca
   137341 ggcagtcgta ggtacaacaa atcctaagca cttgagagaa gttagccgag cggcaaactt
   137401 tagcttaaca agaaaagaat ggtatgaaat ttatcttgct gcagggaata atttgccgta
   137461 agtagtagca ggtttgaata actcacagtc aaaaagccgt ataaagtggt tttttgctat
   137521 aattaaatga agaatgtaga attaaaggag aaaaacatga catttgaaga gatcctgcct
   137581 gggttaaagg ctaagagaaa atatgtacga actggttggg gaggtgcgga aaactatgtc
   137641 caactctttg ataccatcga gcaaaatggg cttgcacttg aaatgacacc ttatttccta
   137701 atcaacgttt ctggagaagg agaaggtttt tccatgtgga gcccgacagt ttgtgatgtt
   137761 ttggcaacgg attgggtaga agtgcatgac taaacgtgta ctcattacag gagtgagttc
   137821 agggatcgga ttggctcaag ctcgcctctt tttagagaag ggctatcaag tttatggagt
   137881 tgaccaaggt gaaaagccac tcttagaggg tgattttcac tttttacaga gagatttgac
   137941 cttggacttg gaacctattt ttgactggtg ccctcaggtg gatgttttgt gtaatactgc
   138001 cggagttttg gatgcttaca aaccactgtt ggaacaaacg gcgcaggaca ttcaagagat
   138061 ttttgaaatc aactacatta ttccagtaga gttgactcgg tattatttga cacaaatgct
   138121 ggaaaataaa aagggaatca tcatcaatat gtgttccatt gcttctagcc tagcaggtgg
   138181 aggtggtcac gcctatactt catccaagca tgccttggct ggcttcacca agcagttggc
   138241 tctagactat gctgaagcta ggattcaggt ctttggtatc gctccaggag cagtcaagac
   138301 agctatgacc gctgcggatt ttgagacagg tggcttagct gactgggtgg ctagtgaaac
   138361 cccaatcaag cgctggattg aaccagagga agtggcagaa gtcagtctct ttttggccag
   138421 tggaaaggca tctgccatgc agggacaaat tctgacaata gatggtggct ggtctttgaa
   138481 gtaggaggag ttggatggaa atcaaaaatc actttggggt ctactgtgtt tgctttgaaa
   138541 atggaaagtt actttgcatt gaaaaaacga gaggccctta tcaacatcgg tatgatctac
   138601 ctggaggcag tcagcaactt ggtgaaggac tgacggaaac gctgactaga gaagttatgg
   138661 aagagacggg atttactgtt agaagctact ctaatcctcg aatctacgat gttttcgtca
   138721 gggaagagtt aaaaaatttt atggttcacc atgtcatagc cttgtatgat gttgaaatga
   138781 atgagagtgc acctcaagtt acgatttcgg aagctgtgtc tgatggtgcg aatgattcac
   138841 ttggatatat ttggatggat attcaagaga ttacagaaga aaatgcatcg ccattagtct
   138901 tgaaggttaa gtctgaatta ttaggattgc cagaactgga caagacttct tacatgaatt
   138961 ggaaggtgaa gtagagggat aatggaacta tttaaaacat ggaagaaaaa tatggttctc
   139021 tatggtctta aatctcaaat tggaactgtc taccgaaaca atgataggac aacaagcttt
   139081 tatgatgttg ggaattttct atacctagca ggggagttgg attccagatt ttgggaagat
   139141 tttgttagaa aatatggttt agattataag attattattt cagaaaatac taattggcaa
   139201 gattttctgc atcgaaaagt ggggctaaat tcttttactc gctattcttt taaagataag
   139261 gcaaattttc aagttgaatt tttaaataat ctagttactc atttagagga aggttacaat
   139321 attgtgccta ttgataatca tatttataac tgcttttcta cggaagaatg gtcacaggat
   139381 ttacaggggg attttgagtc ctatcaggat tttgttttaa aaggtggatt tggctttgtg
   139441 attcttaaaa ataatgaact gattgctggg atttcctcag ggttagttta ccgtaaagca
   139501 gttgaagtgg aagttgcaac tagaccaaac gaacaaggaa atggatttgc taaaaagctt
   139561 ggtgctgcaa tgattctaga gagtttaaat agagatatgt ttccactttg ggatgctcat
   139621 aatgaggctt ccaaaaaagt agcagaattt ttaggatatg agttatctga accttatgaa
   139681 gcttttgaac tagaggaaat tttgatataa ttatatatga tattgtatct tttaagacga
   139741 ggtgaatggc tatgagaaat caacttgccc ttagtggcga aaaaattctt gaaaaaattt
   139801 atcctcaact atttcaccac gtcggcatga ttcgtgggga atatttgttg agagagctta
   139861 atcaaaacat catattagca agttgtcagc aatttgtaaa agattatcta gagactatct
   139921 gctccctgta ctcagatgaa gaagtttggt atcgtttttc tgaattaacg aatacagaag
   139981 ccaattgttt agtggggact agagagtttt ttgacgaagg gcatcccttg tttggctata
   140041 gaggaaccag gcgtttactg gcgtgtttgg atgaatttca ggctgaagca catgtcgtta
   140101 cagaagttta tcaaaccaac cccaatctat ctgttatctt tccttttgtc aatgatgccg
   140161 accaattaaa acaagctatt acagtattgc gtcagcaggg ttttactggg aaagtcggaa
   140221 cgatgattga attaccgtca gcgtattttg acttatctag tatactggaa acgggcattt
   140281 caaagattgt agttggaatg aatgatttga cttcctttgt ttttgcgact atgagaaaca
   140341 gtcaatggca tgatatggaa agtccaataa tgttagatat gctaagagat atgcaggata
   140401 aagcaagaaa gaacaagatt gattttgctg tagcaggcta tctgaatact tctttcatac
   140461 aaaaaatgaa tcagttgggt atcaagtgca ttatccacta cagttctatt ccagagattt
   140521 ttgatttaga gattgaccat ccagatcatc ttaaacacat aaaagaagaa agtaaaaaat
   140581 tacaaaggag tacccatgat accgcaagaa atgtggaata aatacaagca aatcaatcct
   140641 ttgatcggag atgaaatcga tgcttgggct tttggagttg aaccagatct tttagcggat
   140701 ttggtgttta aaggagaaaa gacagcaaca gcatcagcct atgacctcta tgtactagaa
   140761 gacgaaccac ttccccaagt agggaccttc gatatcattt tagatagtca aaatcagtct
   140821 gtctgcattg tcgaaattac aaaggtttct gttgaactct tcaatcaagt ttctgcgcaa
   140881 catgccttta aggaaggtga gggagacaaa tcacttgcct attggcgcca ggttcatgag
   140941 gactttttca cagactgttt gggtgaagta gggctgactt ttacacctga aagcaaggtt
   141001 gttttagaag aatttcgcaa ggtctaccca ctgtagacta ttagaaggaa gaaagttttg
   141061 gaaatcgctg tccaatcctt ttttttcaag caaaatatga tataataagt ttgtttgaag
   141121 aagagcagca gctcttaaac ttagaatagg agaaaactat gcaagcagtt gaacatttta
   141181 ttaagcaatt tgttcctgaa cattatgatt tatttttaga tttgagtcgt gagaccaaga
   141241 ctttttctgg gaaagtgacc atcactggtc aagcacagag tgaccgcatc tccctccacc
   141301 aaaaagactt ggaaatcacc tctgtagaag ttgcaggtca agctcgtcca tttacagttg
   141361 accatgacaa tgaagccctt catatcgaat tggctgaggc tggtcaagtt gaattggttc
   141421 ttgccttttc tggtaaaatt acagacaaca tgacagggat ttacccttct tattatacag
   141481 ttgatggagt caagaaggag gtcttgtcta ctcagttcga gagccatttt gcgcgcgaag
   141541 ctttcccatg tgtggatgag cctgaagcca aagcaacttt tgacctctct cttcgctttg
   141601 accaagcaga aggtgaattg gccttgtcaa acatgccaga aatcgatgtt gaaaaccgta
   141661 aggaaacagg tatctggaag tttgagacaa cacctcgcat gtcttcttac ttgttggcct
   141721 ttgttgctgg tgatttgcaa ggggtgaccg ctaaaactaa aaatggtacc ctggtaggtg
   141781 tctactcaac caaagcacat ccactttcaa atcttgattt ctcactggat atcgctgttc
   141841 gctctatcga gttttacgaa gattactatg gagttaagta tccaattcct caatctctcc
   141901 acatcgccct tcctgacttc tcagctggtg ctatggaaaa ctggggtctt gtgacctacc
   141961 gtgaagttta cttggttgtc gatgagaact ctacatttgc tagccgtcaa caagttgccc
   142021 ttgttgtggc ccatgaattg gctcaccaat ggtttgggaa cctcgtgact atgaaatggt
   142081 gggatgacct ttggctcaat gaaagtttcg ctaatatgat ggaatacgtc tgtgtggata
   142141 ccatcgaacc aagctggaat atctttgaag atttccaaac aggtggagta cctcttgctc
   142201 ttgaacgtga cgctactgat ggcgttcagt ctgtccacgt cgaagttaaa catccagatg
   142261 aaatcaatac actctttgac ggcgctatcg tctatgccaa aggaagccgt ctcatgcaca
   142321 tgcttcgccg ttggctagga gatgctgatt ttgctaaagg tttgcatgcc tactttgaaa
   142381 aacaccaata cagcaacacc attggtagtg acctttggga tgcccttggt caagcgtcag
   142441 gacgtgatgt cgcagccttc atggattctt ggttggaaca gcctggttac ccagttctta
   142501 ctgtcaaagt tgaaaatgat gtcttgaaga tttcacaaaa acaattcttc atcggtgaga
   142561 acgaagacaa gaaccgtctc tgggtggtgc ccctcaatag caactggaaa ggcttgcctg
   142621 atacactcga aactgaaagt atcgaaatcc ctggctacgc agctcttctt gctgaaaatg
   142681 aaggagctct tcgtctcaac actgaaaata ctgcccacta tattaccgac tatcaaggag
   142741 acttgttaga agctgttctt gctgagctag agacacttga taacacaagc aaactgcaaa
   142801 ttgttcaaga acgtcgtttg ttggctgagg cagggcacat ttcttatgca gacttgcttc
   142861 cagttcttga taaacttgct aaggaagagt cttatctggt ggtttcagct gtttctcaag
   142921 tgatttcagc ccttgagcgc tttattgatg aaggaacgga tgctgaaaca gccttcaaag
   142981 gactggttgc taaattggct cgtcataact atgaccgtct tggttttgaa gctaaagacg
   143041 gagaatcaga tgaggatgaa ttggttcgtc agctggctgt ttcgatgatg attcgctcaa
   143101 atgatgcaga agctcgtcaa gtcgctagcc aaatcttcgc aacacacaag gagaatcttg
   143161 cagaactccc agcagctatt cgttcacaag ttctgattaa tgagatgaaa catcatgaga
   143221 ctaaagactt gttagcactt tatcttgata cttatactca cgcaacagat gctgtcttta
   143281 aacgccagtt ggcagcagct cttgcataca gtacagatgc ggataatatc caaaacttga
   143341 ttacttcttg gaaggacaaa tttgtggtca aaccacagga cttgtctgct tggtattacc
   143401 aattcctagc tcatcaagca actcagaaaa cagcttggtc ttgggcgcgt gaaaactggg
   143461 cttggattaa ggcagccctt ggaggagata tgagctttga tagctttgtt atccttcctg
   143521 ctcatgtatt taagactcag caacgcttgg cggaatacaa ggagttcttt gagccgcaac
   143581 tttctgacct tgctcttagc cgtaacatcg gtatgggaat caaggaaatt gcagcacgtg
   143641 ttgacttgat tagccgtgaa aaagctgcag tcgaagcagt tgttcttcaa tacggaaatg
   143701 cataaataag cctaaaataa aaagaaaagg ctctttgtca actgtagtgg gttgaaaaaa
   143761 agctaagctc gagaaaggac aaattttgtc ctttcttttt tgat
//
LOCUS       DBEJHE010000002       127408 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC4 isolate 671759
            SAMN38261586-rid24793303.denovo.02, whole genome shotgun sequence.
ACCESSION   DBEJHE010000002 DBEJHE010000000
VERSION     DBEJHE010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261586
            Sequence Read Archive: SRR26833752
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 127408)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 127408)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576136.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576136.1
            Genome Coverage       :: 109x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 19:48:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,067
            CDSs (total)                      :: 2,029
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 131
            CDSs (without protein)            :: 131
            Pseudo Genes (ambiguous residues) :: 0 of 131
            Pseudo Genes (frameshifted)       :: 64 of 131
            Pseudo Genes (incomplete)         :: 59 of 131
            Pseudo Genes (internal stop)      :: 46 of 131
            Pseudo Genes (multiple problems)  :: 32 of 131
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..127408
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261586-rid24793303.denovo.02"
                     /strain="GPSC4"
                     /isolate="671759"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(104..241)
                     /locus_tag="ACL3EZ_000148"
     CDS             complement(104..241)
                     /locus_tag="ACL3EZ_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004264816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SapB/AmfS family lantipeptide"
                     /protein_id="HGR0391796.1"
                     /translation="MAEEVLNLQLVSVQVDETDEVDGMRFSTFSTNRCGNWSAFSWEN
                     C"
     gene            complement(375..1694)
                     /locus_tag="ACL3EZ_000149"
     CDS             complement(375..1694)
                     /locus_tag="ACL3EZ_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000945307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0391797.1"
                     /translation="MLRLVYYQFLHNKKQWLGVSPVIFVSSLVMGLAVNGVINVENNS
                     QVFVGLPDPKPIFMFPIVFGGVTLFFVLSNIINMLVEIFRDDYELLEVLGASLLQLSF
                     LVGGQIFIISSIISFIAYLCSIFVTSNYYYFLQYFFGENILPDIQFQTSAVGCIITVV
                     LISFLAFLSGCFYTFKKIRNRKSSKIRHVLSIVKRILLLAGFSVIWLLSLQQIFQDST
                     ILAKAQIIFNIVILDIVIIYQLSPFIQSCFIKLLSIIIFRNNFMFIVSKWNLLYRKPY
                     IKSISAAITGAILLISSFQMISQNILSQFQDDSDLELKVAFIVYVGAPILIVLANIIS
                     IAFLSSHQERIEIQQFEILGTSNYQMVKIKVGEAIFLTFVTSLIAFLLNIKIMALIYY
                     SLEDILIDDMNLLGLILPNFIVSIILFILIFITKSSYFIFKNAKIIS"
     gene            complement(1697..2437)
                     /locus_tag="ACL3EZ_000150"
     CDS             complement(1697..2437)
                     /locus_tag="ACL3EZ_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000356590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0391798.1"
                     /translation="MDKDYILKVKGLYHQFLLGNNKTLQVLKNVSLSASRGEFISILG
                     ISGSGKSTLLKCISSLLEPTSGEVILNGINPYKIRNAKLSSIRRNEVSFIFQAYNLIP
                     SLPVIENIALPLRLSQKKLTIKNVENLLKRMKFNAGLNDFVGTLSGGEQQKVAIARAV
                     IADSDIIFADEPTGALDSVSREVIFELLRELVGAGKCVIMVTHDIELASKTDRALILK
                     DGKIFKELHRPSGEELYKILEVQSTTEE"
     gene            complement(2452..4059)
                     /locus_tag="ACL3EZ_000151"
     CDS             complement(2452..4059)
                     /locus_tag="ACL3EZ_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGR0391799.1"
                     /translation="MNYLKFIKKTKLILMGILIFLSSFNGVLLSGIIVYAGSLNQTSS
                     FSDVLRFGAISILGWSAIYISNYYLEVTEASITKDINVKIKQGYFREQYLSSEMVKDY
                     SSIISVLSNDLRLIEENYFRQIFEIISSILLFIVSLSFMLYLNFLVSIIFIVLSALPI
                     IVPVFMKKMLSNSANEYSNSNAEYTHIIKEIFNGFKTLKSYSVTKEIISLSDKKLDKL
                     EDSTFNLKRSEVLSKLVAVLISGFCFLVPLVVGCYFVIYHKSLSFSELIGIFLANDKV
                     LGPIQSIAYSLNKINTTKDLRKPFLKYLSGEKNFIDAEHDNNGLYTSSIDEIHMKDVV
                     YSITPENKLSIDFSFKSPFRVLLTGTSGSGKTTILNLINGSLKPQKGYVNLLSHGKKS
                     SDSIPTVDQTPYIFDTTIRENVTLFQNEYFSDDQIIEVLKKVNLYEELEKIDILNYQC
                     GENGSNLSGGQKQKIALARALIRNNKVYLFDEISANLDNDNSNSIHDILFNLGISFIE
                     VSHHYDLNDKRYTDIYKLENGTLFKIK"
     gene            complement(4056..5996)
                     /locus_tag="ACL3EZ_000152"
     CDS             complement(4056..5996)
                     /locus_tag="ACL3EZ_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S9 family peptidase"
                     /protein_id="HGR0391800.1"
                     /translation="MNQSNEIFLNTIQEKTHYKRSISSSFQELKKWNSLIFRRGRYWY
                     QFDNWSIPNTGVIKEWYVEDNDWIPKVSSSSLDNSNSLKIVFDVEKYTLPDDSILQDV
                     RISSDESYIVLVVSSLRSTNLIGIKKYTMEELFIIEDISVESSFYLGKFGVMYTRSKE
                     YGRPSKLFYKSFDSFTEEELFEENECSFRLKIVHIDSNNCFVKSVDFQKGRIFLYSFD
                     RTGFVRHSYTETVAPTPRDIALFSTEKAQYFLGLSSTEEKKDQLILRETSSGDRVSIT
                     IPYQDRARRVHCIGRYILLDCSNAANSVFYLATFKNNSLRELSVNKITFDEKTTLYEN
                     SFSDRVLLFLERRTFYEKILSFDLIENTLKTEFERPIIKSNNTKYFSKVIWTKKDSYD
                     VSIPISLFWKSEDTDELPRRKKCILSVYGAYGKNDNSDLDEIMLSIIDAGFIYAIVHV
                     RGGGYLGGEWYRSGKALNKWNSIRDFIEGVNYLRENDVIDSKRLGLITSSAGGIIAGA
                     VLNEEKNLLQSILLFSPFINPYDTLQNPNDPLSKTEIAEWGDIRDPEVKAYIKSYSPM
                     QNIEKARDSNTVIVNILGEKDPYINNNEVIEWSKKLNSIGVKSLLYLNKAAGHGGFTP
                     SDVLLMIDTLNYFFEEVGRNNL"
     gene            complement(6029..6493)
                     /locus_tag="ACL3EZ_000153"
     CDS             complement(6029..6493)
                     /locus_tag="ACL3EZ_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic synthetase"
                     /protein_id="HGR0391801.1"
                     /translation="MAVDKELVAYKVDSNNSLQYSQGHRLLPYLATGSAGLLLLINRN
                     KEILSSKYLKYLTSLERATDVVFCVLPGLFNGFCGLEVANNIYSDIDDNFSGQKKLIE
                     QLYRYLCVIEEGFVIAGDNGLKITTDIASGFAGVAIGLVSIMDNKLTILPQI"
     gene            complement(6518..8527)
                     /locus_tag="ACL3EZ_000154"
     CDS             complement(6518..8527)
                     /locus_tag="ACL3EZ_000154"
                     /inference="COORDINATES: protein motif:HMM:NF017000.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0031179 - peptide modification [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lanthionine synthetase LanC family protein"
                     /protein_id="HGR0391802.1"
                     /translation="MNNDEWVYQYPIGKFVERQGWKIHISSEYNSSHELLQDVAKICH
                     EMRIPFKHLSTEDKFIMRNGKLVSRGFSGKFITCYPNQNELESVLQRLESALKQYNGP
                     YILSDKRWDEAPIYLRYGVFRPSRDDEKKVAIDELIVGDEVVKDERLPVFKIPKGIVP
                     PDFLNKWLDKKDKKQGDFPFIIDNAIRFSNSGGIYNARLKEDGKKIILKEARPYTGLG
                     FDGTYSSEKLASECKALKILNEWSETPKIYWHGKIWEHTFLGIEHMKGVPLNRWVTNN
                     FPLYEVVDKTKDYLLRVSKIVEKLIDLTNKFHSENVYHQDLHLGNILVKDEDEISIID
                     WEQAVFSNDEKVVHKVAAPGFRAWRETLPSEIDWYGIRQIAHYLYMPLVTTSDLTYNY
                     VSQTRIEGKKLFESLGYTREHIDYVESLLSYLDSKCPQIENISRKKVLKPMHEIRTIE
                     SEQDIQDFIIKLLRGFTLTYGQWRKEFQSRFFPVHYYGLNFNQGIAFSDLAILWSYQQ
                     LAKKVKNFKFDDYYEIRTQVINEAVNNFKKSSLSGLFDGKIGTIWLIYEFGEIDRAVE
                     LFTTHFIEIFENSQNKNLYSGQAGILLVGLYFLSKGEIDNKLGEEILIRLREYTLNYI
                     ENPETFCKVGASDVQSNDPYENFGGLLYGHAGVAWLFGEAYKLTG"
     gene            complement(8817..8954)
                     /locus_tag="ACL3EZ_000155"
     CDS             complement(8817..8954)
                     /locus_tag="ACL3EZ_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004264816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SapB/AmfS family lantipeptide"
                     /protein_id="HGR0391803.1"
                     /translation="MAEEVLNLQLVSVQVDETDEVDGMRFSTFSTNRCGNWSAFSWEN
                     C"
     gene            complement(9156..9743)
                     /locus_tag="ACL3EZ_000156"
     CDS             complement(9156..9743)
                     /locus_tag="ACL3EZ_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="HGR0391804.1"
                     /translation="MKRIIPVYIFQQVNVLLVSLYLLKFLCIGELTILQILYGSSLIS
                     FLWMYGQRKQAHKVNMKSRMKWLGIGFVSLLIISLCFSLIHAQESTNQANLIGLQHQV
                     PWFSFLLFLINASMVEEFLYREILWNLVRKLDIRVALTSVLFALAHHPGTIIAWCLYV
                     SLGMFLGLVRYKLDLWGSMGLHLVWSLLVYSLLLF"
     gene            complement(9930..10298)
                     /gene="rplL"
                     /locus_tag="ACL3EZ_000157"
     CDS             complement(9930..10298)
                     /gene="rplL"
                     /locus_tag="ACL3EZ_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HGR0391805.1"
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAVAAA
                     DAADAGAAKDSFDVELTSAGDKKVGVIKVVREITGLGLKEAKELVDGAPALVKEGVAT
                     AEAEEIKAKLEEAGASVTLK"
     gene            complement(10374..10874)
                     /gene="rplJ"
                     /locus_tag="ACL3EZ_000158"
     CDS             complement(10374..10874)
                     /gene="rplJ"
                     /locus_tag="ACL3EZ_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HGR0391806.1"
                     /translation="MSEAIIAKKAELVDVVAEKMKAAASIVVVDARGLTVEQDTVLRR
                     ELRGSEVEYKVIKNSILRRAAEKAGLEDLASVFVGPSAVAFSNEDVIAPAKILNDFSK
                     NAEALEIKGGAIEGAVASKEEILALATLPNREGLLSMLLSVLQAPVRNVALAVKAVAE
                     SKEDAA"
     misc_feature    complement(10913..11048)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            complement(11124..12383)
                     /locus_tag="ACL3EZ_000159"
     CDS             complement(11124..12383)
                     /locus_tag="ACL3EZ_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRZ/ATZ family protein"
                     /protein_id="HGR0391807.1"
                     /translation="MKVFQHVNIVTCDQDFHVYLDGILAVKDSQIVYVGQDKPAFLEQ
                     AEQIIDYQGAWIMPGLVNCHTHSAMTGLRGIRDDSNLHEWLNDYIWPAESEFTPDMTT
                     NAVKEALTEMLQSGTTTFNDMYNPNGVDIQQIYQVVKTSKMRCYFSPTLFSSETETTA
                     ETISRTRSIIDEILKYKNPNFKVMVAPHSPYSCSRDLLEASLEMAKELNIPLHVHVAE
                     TKEESGIILKRYGKRPLAFLEELGYLDHPSVFAHGVELNEREIERLASSQVAIAHNPI
                     SNLKLASGIAPIIQLQKAGVAVGIATDSVASNNNLDMFEEGRTAALLQKMKSGDASQF
                     PIETALKVLTIEGAKVLGMENQIGSLEVGKQADFLVIQPQGKIHLQPQENMLSHLVYA
                     VKSSDVDDVYIAGEQVVKQGQVLTVEL"
     gene            complement(12685..14433)
                     /locus_tag="ACL3EZ_000160"
     CDS             complement(12685..14433)
                     /locus_tag="ACL3EZ_000160"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0391808.1"
                     /translation="MKRQTVNQTLKRLAVDLANHPFLLFLAFLGTIAQVGLSIYLPIL
                     IGQVIDQVLVAGSSPVFWQIFLQMLLVVIGNTLVQWANPLLYNRLIFSYTRDLRERII
                     HKLHRLPIAFADRQGNGEMVSRVTTDIEQLAAGLTMIFNQFFIGVLMILVSILAMLQI
                     HLLMTLLVLLLTPLSMVISRFIAKRSYHLFQKQTETRGIQTQLIEESLSQQTIIQSFN
                     AQTEFIQRLREAHDNYSGYSQSAIFYSSTVNPSTRFVNALIYALLAGVGAYRIMMGST
                     LTVGRLVTFLNYVQQYTKPFNDISSVLAELQSALACVERIYGVLDSTEVAETGKEVLT
                     SDQVKGAISFKHVSFGYHPEKILIKDLSIDIPAGSKIAIVGPTGAGKSTLINLLMRFY
                     PISSGDILLDGQSIYDYTRASLRQQFGMVLQETWLTQGTIHDNIAFGNPEASREQVIA
                     AAKAANADFFIQQLPQGYDTKLENAGESLSVGQAQLLTIARVFLAIPKILILDEATSS
                     IDTRTEVLVQDAFAKLMKGRTSFIIAHRLSTIQDADLILVLVDGDIVEYGNHQELMDR
                     KGKYYQMQKAAAFSSE"
     gene            complement(14435..16159)
                     /locus_tag="ACL3EZ_000161"
     CDS             complement(14435..16159)
                     /locus_tag="ACL3EZ_000161"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0391809.1"
                     /translation="MKHLLSYFKPYIKESILAPLFKLLEAVFELLVPMVIAGIVDQSL
                     PQGDQGHLWMQIGLLLIFAVIGVLVALIAQFYSAKAAVGFAKELTNDLYRHILSLPKD
                     SRDRLTTSSLVTRLTSDTYQIQTGINQFLRLFLRAPIIVFGAIFMAYRISAELTFWFL
                     VMVAILTIVIVGLSRLVNPLYSSLRKKTDQLVQETRQQLQGMRVIRAFGQEKRELQIF
                     QTLNQVYARLQEKTGFWSSLLTPLTYLIVNGTLLVIIWQGYISIQGGVLSQGALIALI
                     NYLLQILVELVKLAMLINSLNQSYISAKRIEEVFAESPENIHSELEQKQVTSGRVLQV
                     QELTFTYPDAAQPSLRYISFDMTQGQILGIIGGTGSGKSSLVQLLLGLYPIDKGSIDL
                     YRDGSSPRNLEQWRSWIAYVPQKVELFKGTIRSNLTLGLNQEVTDQELWQALEIAQAK
                     DFVSDKEGLLDALVEAGGRNFSGGQKQRLSIARAVLRQAPFLILDDATSALDTITESK
                     LLKAIRENFPNMSLILISQRTSTLQMADQILLLEKGELLAVGKHDDLMKSSQVYREIN
                     ASQHGKED"
     gene            complement(16217..17155)
                     /gene="msrB"
                     /locus_tag="ACL3EZ_000162"
     CDS             complement(16217..17155)
                     /gene="msrB"
                     /locus_tag="ACL3EZ_000162"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033743 - peptide-methionine (R)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HGR0391810.1"
                     /translation="MAEIYLAGGCFWGLEEYFSRISGVLETSVGYANGQVETTNYQLI
                     KETDHAETVQVIYDEKEVSLREILLYYFRVIDPLSINQQGNDRGRQYRTGIYYQDEAD
                     LPAIYTVVQEQERMLGRKIAVEVEQLRHYILAEDYHQDYLRKNPSGYCHIDVTDADKP
                     LIDAANYEKPSQEVLKASLSEESYRVTQEAATEAPFTNAYDQTFEEGIYVDITTGEPL
                     FFAKDKFASGCGWPSFSRPISKELIHYYKDLSHGMERIEVRSRSGSAHLGHVFTDGPR
                     ELGGLRYCINSASLRFVAKDEMEKAGYGYLLPYLNK"
     gene            complement(17450..18319)
                     /gene="thrB"
                     /locus_tag="ACL3EZ_000163"
     CDS             complement(17450..18319)
                     /gene="thrB"
                     /locus_tag="ACL3EZ_000163"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000692406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004413 - homoserine kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0009088 - threonine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HGR0391811.1"
                     /translation="MKIIVPATSANIGPGFDSVGVAVTKYLQIEVCEERDEWLIEHQI
                     GKWIPHDERNLLLKIALQIVPDLQPRRLKMTSDVPLARGLGSSSSVIVAGIELANQLG
                     QLNLSDHEKLQLATKIEGHPDNVAPAIYGNLVIASSVEGQVSAIVADFPECDFLAYIP
                     NYELRTRDSRSVLPKKLSYKEAVAASSIANVAVAALLAGDMVTAGQAIEGDLFHERYR
                     QDLVREFAMIKQVTKENGAYATYLSGAGPTVMVLASHDKMPTIKAELEKQPFKGKLHD
                     LRVDTQGVRVEAK"
     gene            complement(18321..19607)
                     /locus_tag="ACL3EZ_000164"
     CDS             complement(18321..19607)
                     /locus_tag="ACL3EZ_000164"
                     /EC_number="1.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004412 - homoserine dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HGR0391812.1"
                     /translation="MTVKIALLGFGTVASGVPFLLKENGGKINQSAHSDIKVAKVLVK
                     DEDEKNRLLAAGNDFNFVTNVDDILSDHDITIVVELMGRIEPAKTFITRALEAGKHVV
                     TANKDLLAVHGAELLEIAQANKVALYYEAAVAGGIPILRTLANSLASDKITRVLGVVN
                     GTSNFMVTKMVEEGWSYDDALAEAQRLGFTESDPTNDVDGIDAAYKMVILSQFAFGMK
                     IAFDDVAHKGIRNITPEDVAVAQELGYVVKLVGSIEETSSGIAAEVTPTFLPKAHPLA
                     SVNGVMNAVFVESIGIGESMYYGPGAGQKPTATSVVADIVRIVRRLNDGTIGKDFNEY
                     SRDLVLANPEDVKANYYFSILALDSKGQVLKLAEIFNAQDISFKQILQDGKEGDKARV
                     VIITHKINKAQLENVSAELKKVSEFDLLNTFKVLGE"
     gene            complement(19758..20495)
                     /gene="mecA"
                     /locus_tag="ACL3EZ_000165"
     CDS             complement(19758..20495)
                     /gene="mecA"
                     /locus_tag="ACL3EZ_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HGR0391813.1"
                     /translation="MKMKQISDTTLKITMSLEDLMDRGMEIADFLVPQEKTEEFFYAI
                     LDELEMPDSFLDTGMLSFRVTPKPDKVDVFVTKSKIDQNLDFEDLSDLPDMEELAQMS
                     PDEFIKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQAEQEAESKKEPYIYYILSFA
                     KLADLVVFAKTVTFEMETSELYKMNERYYLTILVDIENHPSPYPAWLLARMREFADDS
                     DISRSVLQEYGQVLMSHDAVLNLQKIG"
     gene            complement(20695..21729)
                     /locus_tag="ACL3EZ_000166"
     CDS             complement(20695..21729)
                     /locus_tag="ACL3EZ_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HGR0391814.1"
                     /translation="MFEHYSVADLFANLYKKRKANILALIALFALIAVPFTIKAVRNK
                     NTVKDTTSYSTYLIYKITPPKESAKTILNHQIGGYSDFYGKLIDGNLNGAYLFNDVEP
                     SELKKIASELDTTETTLKNSTNDYWWKKLTVYYMIDDAGVGVKILTSSKDANDLLEKK
                     IDGLIEKFKHAYANVKIEKLETINSKELNANGETALGLNVKNLILRLVVIGVVCVILV
                     VMGNVLVYLFNPTINRVGDFSQYQIDFVTEITTIANLADVLSYKNTGQELTIVSSNKA
                     ILDKLKQSQEALKGMHFVDLQDVSSLLERDTVLLVEEYGVTRYKKFEQSLQILRNLNR
                     SILGVATFKL"
     gene            complement(21758..23191)
                     /locus_tag="ACL3EZ_000167"
     CDS             complement(21758..23191)
                     /locus_tag="ACL3EZ_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polysaccharide polymerase Wzy family
                     protein"
                     /protein_id="HGR0391815.1"
                     /translation="MIDGKRLLFSLTIVSYALTLVSGIVYLFNNNNVSLLSTLLFLLV
                     SSLIACWNDIKYYLIHFIFYLTIFVFLVSRPTIDYFRDGALDTYHPIAYRFAFIVVMV
                     SILGLTTGGILARYFIARKKIKVANIGNSLKEVYIKRLRFVSLGVFLLTYPFYFIRLF
                     ERLLYRLQTSYYAYYANFESKLPYFTYILSTFTVYAMCMYLATKPKKLQATAVLVSFI
                     AANTIHLAIGTRNPFILSILFAFVYYFMREQTEKGKWIGFKEKLAIFVGSPILMLAMG
                     VLNYVRDNVQVSHTGFWDILLDFIYKQGTSFGVLARGFLFNSSLPYRDFRNFTFGPVL
                     DYFARGSLGAIFGGKAFEHTTNSVELAIDSNSYAHNLSYLVLNKEYLKGHGIGSSYIM
                     ELYTDYGMIGVFLLSFLLGVLFIAMLQVAYRSRTILFALSLLILNNLFFMPRSSFSES
                     FFNLFTMQFWGIVLVIIFVAKMLTKEN"
     gene            complement(23207..24193)
                     /locus_tag="ACL3EZ_000168"
     CDS             complement(23207..24193)
                     /locus_tag="ACL3EZ_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000446977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HGR0391816.1"
                     /translation="METALISVIVPVYNVAQYLEKSIASIQKQTYQNLEIILVDDGAT
                     DESGRLCDSIAEQDDRVSVLHKKNEGLSQARNDGMKQAHGDYLIFIDSDDYIHPEMIQ
                     SLYEQLVQEDADVSSCGVMNVYANDESPQSANQDDYFVCDSQTFLKEYLIGEKIPGTI
                     CNKLIKRQIATALSFPKGLIYEDAYYHFDLIKLAKKYVVNTKPYYYYFHRGDSITTKP
                     YAEKDLAYIDIYQKFYNEVVKNYPDLKEVAFFRLAYAHFFILDKMLLDDQYKQFEAYS
                     QIHRFLKGHAFAISRNPIFRKGRRISALALFINISLYRFLLLKNIEKSKKLH"
     gene            complement(24195..25298)
                     /locus_tag="ACL3EZ_000169"
     CDS             complement(24195..25298)
                     /locus_tag="ACL3EZ_000169"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HGR0391817.1"
                     /translation="MVAKKKILFFMWSFSLGGGAEKILSTIVSNLDPEKYDIDILEME
                     HFDKGYESVPKHVRILKSLQDYRQTRWLRAFLWRMRIYFPRLARRLLVKDDYDVEVSF
                     TIMNPPLLFSKRREVKKISWIHGSIEELLKDSSKRESHRSQLDAANTIVGISKKTSNS
                     IKEVYPDYTSKLQTIYNGYDFQTILEKSQEKIDIEIAPQSICTIGRIEENKGSDRVVE
                     VIRLLHQEGKNYHLYFIGAGDMEEELKKRVKEYGIEDYVHFLGYQKNPYQYLSQTKVL
                     LSMSKQEGFPGVYVEALSLGLPFISTNVGGAEELSQEGRFGQIIESNQEAAQAITNYM
                     TSASNFDVDEASQFIQQFTITKQIEQVEKLLEE"
     gene            complement(25288..26133)
                     /locus_tag="ACL3EZ_000170"
     CDS             complement(25288..26133)
                     /locus_tag="ACL3EZ_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HGR0391818.1"
                     /translation="MNNMTDLKAIQARSLEMAEYFVAFCKEHDLLCYLCGGGAIGALR
                     NKGFIPWDDDLDFFMPRKDYEKLAELWPRYADERYFLSKSHKDFVDRNLFITIRDKET
                     TCIKPYQQDLDLPHGLALDVLPLDYYPKNPAERKKQVRWALIYSLFCAQTIPEKHGAL
                     MKWGSRILLGLTPKSLCYRIWKKAEKEMTKYDLADCDGITELCSGPGYMRNKYPITSF
                     EDNLFLPFEGTEMPIPIGYDVYLRTAFGDYMTPPPADKQVPHHDAVIADMDKSYTEYK
                     GEYGG"
     gene            complement(26412..27686)
                     /gene="psr"
                     /locus_tag="ACL3EZ_000171"
     CDS             complement(26412..27686)
                     /gene="psr"
                     /locus_tag="ACL3EZ_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyisoprenyl-teichoic acid--peptidoglycan
                     teichoic acid transferase Psr"
                     /protein_id="HGR0391819.1"
                     /translation="MSKENPLSHHEQLRYDYLLKNIHYLNEREKNEFAYLQEKLTLAR
                     GNSSSSLEQEREEQVDLPSYANRSRSQSKSQALSSPPKKKRRKLRLKRIFMVIFSLLV
                     CVALAMVFMFLRGYQDASAKKTADARAAQVEVFNGQDTRDGVNILIMGTDGRIGQNSV
                     ETRTDSIMVLNVGGSDKKMKLVSFMRDNLVYIDGYSQVINGRKQTDNKLNVAYELGEQ
                     EGQKGAEMVRQVLKDNFDLDIKYYALVDFQAFATAIDTLFPDGVTIDAQFSTLNGRPL
                     TEATVGDDLYATETESPTQTIKVGKQQMNGSTLLNYARFRDDDEADYGRTKRQQQVLT
                     AILEQIKDPTKLFTGSEALGKVFAMTSTNVPYTFLLTNGLSVLDGAKNGIEKLTIPEL
                     GDWVDAYDVYGGLGLLVDQNKYQTKLAQMGLR"
     gene            complement(27683..28531)
                     /gene="pheA"
                     /locus_tag="ACL3EZ_000172"
     CDS             complement(27683..28531)
                     /gene="pheA"
                     /locus_tag="ACL3EZ_000172"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004664 - prephenate dehydratase activity
                     [Evidence IEA];
                     GO_process: GO:0009094 - L-phenylalanine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HGR0391820.1"
                     /translation="MKIAYLGPKGSFSHHVVQTAFPHEELQAFANITDVIKAYEQGLV
                     DYSVVPVENSIEGSIHETLDYLFHQAHIQAVAEIVQPIHQQLMVVPGHTKIEKIFSHP
                     QALAQGKKFIDEQYPEAQIEVTASTAYAARFISEHPDQPFAAVAPRSSAEEYGLELIA
                     EDIQEMEANFTRFWVLGAEKPSIPLQAQTEKMSLALTLPDNLPGALYKALSTFAWRGI
                     DLTKIESRPLKTALGEYFFIIDVDYTDKDLVHFAQKELEAIGIQYKILGAYPIYPISD
                     HGKERR"
     gene            complement(28528..29004)
                     /locus_tag="ACL3EZ_000173"
     CDS             complement(28528..29004)
                     /locus_tag="ACL3EZ_000173"
                     /EC_number="2.7.1.71"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004765 - shikimate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HGR0391821.1"
                     /translation="MAKVLLGFMGAGKSTIARGLDPNYLDMDALIEKRLGMSIANFFA
                     EKGESAFRQVESEVLADLLQTDQVVSTGGGVVISQRNRDLLKTNTDNIYLKADFETLY
                     QRIAADKDNQRPLFLNNSKEELVAIFQERQAWYEEVASRVLDVTKLSPEEIIEELR"
     gene            complement(28997..30280)
                     /gene="aroA"
                     /locus_tag="ACL3EZ_000174"
     CDS             complement(28997..30280)
                     /gene="aroA"
                     /locus_tag="ACL3EZ_000174"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004236106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003866 - 3-phosphoshikimate
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HGR0391822.1"
                     /translation="MKLKTNIRHLHGSIRVPGDKSISHRSIIFGSLAEGETKVYDILR
                     GEDVLSTMQVFRDLGVEIEDKDGVITIQGVGMAGLKAPQNALNMGNSGTSIRLISGVL
                     AGADFEVEMFGDDSLSKRPMDRVTLPLKKMGVSISGQTERDLPPLRLKGTKNLRPIHY
                     ELPIASAQVKSALMFAALQAKGESVIIEKEYTRNHTEDMLKQFGGHLSVDGKKITVQG
                     PQKLTGQKVVVPGDISSAAFWLVAGLIAPNSRLVLQNVGINETRTGIIDVIRAMGGKL
                     EITEIDPVAKSATLIVESSDLKGTEICGALIPRLIDELPIIALLATQAQGVTVIKDAE
                     ELKVKETDRIQVVADALNSMGADITPTADGMIIKGKSALHGARVNTFGDHRIGMMTAI
                     AALLVADGEVELDRAEAINTSYPSFFDDLESLIHG"
     gene            complement(30372..30710)
                     /locus_tag="ACL3EZ_000175"
     CDS             complement(30372..30710)
                     /locus_tag="ACL3EZ_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HGR0391823.1"
                     /translation="MSNIYDSANELSRGLRGLPEYKAVKAAKDAIAADAEASKIFTEY
                     LAFQEEIQKLAQTGQMPDASFQAKMEGFGKQIQGNSLLSEFFTKQQQLAIYLSDIEKI
                     VFEPVSELLK"
     gene            complement(30721..31824)
                     /locus_tag="ACL3EZ_000176"
     CDS             complement(30721..31824)
                     /locus_tag="ACL3EZ_000176"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HGR0391824.1"
                     /translation="MAKTIYIAGLGLIGASMALGIKRDHPDYEILGYNRSQASRDIAL
                     KEGMIDRATDDFASFAPLADVIILSLPIKQTIAFIKELANLDLREGVIISDAGSTKST
                     IVDAAEQYLAGKSVRFVGAHPMAGSHKTGAASADVNLFENAYYIFTPSSLTSQDTLKE
                     MKDLLSGLHARFIEIDAKEHDRVTSQISHFPHILASSLMEQTAVYAQEHEMARRFAAG
                     GFRDMTRIAESEPGMWTSILLSNSETILDRIEDFKERLEAIGQAISKGDEEQIWNFFN
                     QAREQRQTMEIHKRGGVDSSYDLYVDVPDEEDVILRILELLRGTSLVNIHINEENRED
                     IHGILQISFKNAQDLERAEYLITENTDYTVVIK"
     gene            complement(31834..33000)
                     /gene="aroC"
                     /locus_tag="ACL3EZ_000177"
     CDS             complement(31834..33000)
                     /gene="aroC"
                     /locus_tag="ACL3EZ_000177"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004107 - chorismate synthase activity
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HGR0391825.1"
                     /translation="MRYLTAGESHGPRLTAIIEGIPAGLPLTAEDINEDLRRRQGGYG
                     RGGRMKIESDQVVFTSGVRHGKTTGAPITMDVINKDHQKWLDIMSAEDIEDRLKSKRK
                     ITHPRPGHADLVGGIKYRFDDLRNSLERSSARETTMRVAVGAVAKRLLAELDMEIANH
                     VVVFGGKEIDVPENLTVAEIKQRAAQSEVSIVNQEREQEIKDYIDQIKRDGDTIGGVV
                     ETVVGGVPVGLGSYVQWDRKLDARLAQAVVSINAFKGVEFGLGFEAGYRKGSQVMDEI
                     LWSKEDGYTRRTNNLGGFEGGMTNGQPIVVRGVMKPIPTLYKPLMSVDIETHKPYKAT
                     VERSDPTALPAAGMVMEAVVATVLAQEILEKFSSDNLEELKEAVAKHRDYTKNY"
     gene            complement(33010..34077)
                     /gene="aroB"
                     /locus_tag="ACL3EZ_000178"
     CDS             complement(33010..34077)
                     /gene="aroB"
                     /locus_tag="ACL3EZ_000178"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003856 - 3-dehydroquinate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HGR0391826.1"
                     /translation="MKIRIDIPHHPYDIQIEKGCMAQAGQWLRELWQPQKVVIVTDNH
                     VASLYAEKVKLSLEDAGFQVAVFDFLEGEERKNLTTVQKVYEFLVKQGLTRSDGIVAL
                     GGGVVGDLAGFVASTYMRGIHFVQIPTSLTAQVDSSIGGKTGVNTPFAKNMVGTFAQP
                     DGVLIDPLVLETLGKRELIEGMGEVIKYGLIEDPELWALLTGLNGSVESILEHAETLI
                     EHSCQVKRKMVVEDELDNGIRLYLNFGHTIGHAIEATAGYGKVMHGEAVAMGMVQISK
                     VAEEKGLMPAGITQSITEMCQKFGLPVDYENWEVDKFYQALTHDKKARGNTLKLVLVP
                     ELGSATIHPVSLEEMKDYLVK"
     gene            complement(34096..34950)
                     /locus_tag="ACL3EZ_000179"
     CDS             complement(34096..34950)
                     /locus_tag="ACL3EZ_000179"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HGR0391827.1"
                     /translation="MKLDGYTRLTAVVANPIKHSISPFIHNRAFEATATNGAYVAWEI
                     EASDLAETVANIRRYQMFGINLSMPYKEQVIPYLDELSDEARLIGAVNTVVNENGNLI
                     GYNTDGKGFFKCLPSFTISGKKMTLLGAGGAAKSILAQAILDGVSQISVFVRSVSMEK
                     TRPYLDKLQEQTGFKVDLCALEYVSELQARIAESDLLVNATSVGMDGQSSPVPENIVL
                     PETLLVADIIYQPFETPFLKWARSQGNPAVNGLGMLLYQAAEAFQLWTGKEMPTEEIW
                     QSLTEKYQ"
     gene            complement(34940..35617)
                     /gene="aroD"
                     /locus_tag="ACL3EZ_000180"
     CDS             complement(34940..35617)
                     /gene="aroD"
                     /locus_tag="ACL3EZ_000180"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003855 - 3-dehydroquinate dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HGR0391828.1"
                     /translation="MKLIVSVMPRSLEEAQALDATRYLDADIIEWRADYLPKEAILQV
                     APAIFEKFAGRELVFTLRTRSEGGEIDLSPEEYIHLIKEVAQLYQPDYIDFEYYSYKD
                     VFEEMLDFPNLVLSYHNFQETPENMMEILSELTILNPKLVKVAVMAHTEQDVLDLMNY
                     TRGFKTLNPEQEYVTISMGKVGKVSRITADVTGSSWSFASLDEASAPGQISLASMKKI
                     REILDEA"
     gene            complement(35614..36777)
                     /locus_tag="ACL3EZ_000181"
     CDS             complement(35614..36777)
                     /locus_tag="ACL3EZ_000181"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HGR0391829.1"
                     /translation="MNRIRVSKRVEKKLAKGLVLLEASDLENVNLKDQEVEVQGQEGN
                     FLGTAYLSQQNKGLGWFVSKDKVTFNQTFFETLFRKAKEKRNAYYQDDLTTAFRLFNQ
                     EGDGFGGLTVDLYGDYAVFSWYNSYVYQIRQTISEAFRQVFPEVLGAYEKIRFKGFDY
                     ESAHVYGQEAPDFFTVLENGVLYQVFMNDGLMTGIFLDQHEVRGSLVDGLAMGKSLLN
                     MFSYTAAFSVAAAMGGASQTTSVDLAKRSQELSQAHFQANGLSTDEHRFIVMDVFEYF
                     KYAKRKDLTYDVIVLDPPSFARNKKQTFSVAKDYHKLISQSLEILNPGGIIIASTNAA
                     NVSRQKFTEQIDKGFAGRSYQILNKYGLPADFAYNKKDESSNYLKVISMKVSK"
     gene            complement(37132..37392)
                     /locus_tag="ACL3EZ_000182"
     CDS             complement(37132..37392)
                     /locus_tag="ACL3EZ_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0391830.1"
                     /translation="MIKIGNQKYIGRNVLNKKYNIVLFLLFIVYLFGYFSISKTLIPI
                     MCLFQVFLIEHIFRVRNRMMQIGEIIIIVASIILFIDSIFSL"
     gene            complement(37464..39098)
                     /locus_tag="ACL3EZ_000183"
     CDS             complement(37464..39098)
                     /locus_tag="ACL3EZ_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001237556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0391831.1"
                     /translation="MRLKVIKKLVDINILYSSQEANLVNLRKKQAKNPGKKVNVSARV
                     LSSYIFSSLLMLICFSNIAIHFPFEEMPIYFSSMVAILLVIAFSTSLTAFYNVFYESK
                     DLVSYRPYAFKESEIIIAKGLSVLLPALTGIVPILAYFLVLYIRLAPSLWLGLPLMLL
                     SLTLLFVSVALVMVVAVHFLAQTRVFRKYQSIFSNVMIGIGVLIPLIFVFFLQSTFGS
                     IVDKVRDIPFLLYPLHIFYKIAVEPFSTEALVGLLAWIALTVFLLYLTKKKVLPRFYD
                     VILLNSEEKVKKERRSKERISTTKKGFFRMVLRYHLTLLGQGTGVITVLFTSTFLPYL
                     MMISLISKIRDSQIVPDIHPPYWLPLFFVGVFIAVVNNNITSLHSIALSLERENVDFL
                     KSLPFDFARYVKVKFWIIFAVQSFLPVLTLLGLSLYLGLSILSMIYLLVVWIIASVIL
                     SCHHYFKDVKNLSTNWSSITDLVNRSNGIVAIVLLFIYSAILMALVIGSIFLVQSLSP
                     ILAINLGVGALILLLALAIFGYHYYLSRILAEIEKR"
     gene            complement(39079..39828)
                     /locus_tag="ACL3EZ_000184"
     CDS             complement(39079..39828)
                     /locus_tag="ACL3EZ_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0391832.1"
                     /translation="MIEFQNVSKLYGDKEALSNLNLQIENGEIMGLIGHNGAGKSTTI
                     KSLVSIISPSSGRILVDGQELSENRLAIKRKIGYVADSPDLFLRLTANEFWELIASSY
                     DLTSSDLETSLARLLNVFDFAENRYQVIETLSHGMRQKVFVIGALLSDPDIWVLDEPL
                     TGLDPQAAFDLKQMMKEHAQKGKTVLFSTHVLEVAEQVCDRIAILKKGHLIYCGSVED
                     LRKDYPAQSLESIYLSLAGRKEEVADASQGH"
     gene            40007..41461
                     /locus_tag="ACL3EZ_000185"
     CDS             40007..41461
                     /locus_tag="ACL3EZ_000185"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004556 - alpha-amylase activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HGR0391833.1"
                     /translation="MQNQTLMQYFEWYLPHDGQHWTRLAENAPHLAHLGISHVWMPPA
                     FKATNEKDVGYGVYDLFDLGEFNQKGTVRTKYGFKEDYLQAIQALKEQGIQPMADVVL
                     NHKAAADNREAFQVIEVDPVDRTVELGEPFTINGWTSFTFDGRQDTYNGFHWHWYHFT
                     GTDYDAKRSKSGIYLIQGDNKGWANEELVDNENGNYDYLMYADLDFKHPEVIQNIYDW
                     ADWFMETTGVAGFRLDAVKHIDSFFMRNFIRDMKEKYGDDFYVFGEFWNPDKEANLDY
                     LEKTEEHFDLVDVRLHQNLFEASQAGANYDLRGIFTDSLVELKPDKAVTFVDNHDTQR
                     GQALESTVEEWFKPAAYALILLRQDGLPCVFYGDYYGISGQYAQEDFKEILDRLLAIR
                     KDLAYGEQNDYFDHANCIGWVRSGAENQSPIAVLISNDQENSKSMFVGQEWTNQTFVD
                     LLGNHQGQVTIDEEGYGQFPVSARSVSVWAVNTI"
     gene            complement(41551..44169)
                     /gene="alaS"
                     /locus_tag="ACL3EZ_000186"
     CDS             complement(41551..44169)
                     /gene="alaS"
                     /locus_tag="ACL3EZ_000186"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004813 - alanine-tRNA ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006419 - alanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HGR0391834.1"
                     /translation="MKQLSSAQVRQMWLDFWATKAHSVEPSVSLVPVNDPTLLWINSG
                     VATLKKYFDGTIIPENPRITNAQKAIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRD
                     EAITWAYELLTSPEWFDFPAEKLYMTYYPDDKDSYNRWIEVGVDPSHLIPIEDNFWEI
                     GAGPSGPDTEIFFDRGEAFDPENIGLRLLAEDIENDRYIEIWNIVLSQFNADPAVPRS
                     EYKELPHKNIDTGAGLERLVAVIQGAKTNFETDLFMPIIREVEKLSGKVYDQDGDNMS
                     FKVIADHIRSLSFAIGDGALPGNEGRGYVLRRLLRRASMHGQKLGINEPFLYKLVPTV
                     GKIMESYYPEVLEKRDFIEKIVKSEEESFARTLHSGQHFAQGIVADLKEKGQSVIAGS
                     DVFKLYDTYGFPVELTEEIAEEAGMTVDREGFEAAMKEQQERARASAVKGGSMGMQNE
                     TLQNITVESVFNYNASQLSSKLVAIVADNAEVEAVSEGTASLIFAETSFYAEMGGQVA
                     DYGQILDESGKVVATVTNVQKAPNGQALHTVEVLAPLALNQEYTLAIDSNRRHRVMKN
                     HTATHLLHAALHNILGNHATQAGSLNEVEFLRFDFTHFQAVTAEELRAIEQQVNEKIW
                     EALEVKTVETDIDTAKEMGAMALFGEKYGKEVRVVTIGDYSIELCGGTHVGNTSEIGL
                     FKIVKEEGIGSGTRRILAVTGKEAFEAYREQEDALKAVAAILKAPQVKEVPHKVEGLQ
                     EQLRQLQKENAELKEKAAAAAAGDIFKDAKEVNGHRYIASQVSVSDAGALRTFADNWK
                     QKDYSDLLVLVAAIGDKVNVLVASKTKDLHAGNLVKELAPIIDGRGGGKPDMAMAGGS
                     NQAKIQELLDAVAGKL"
     gene            complement(44191..44676)
                     /locus_tag="ACL3EZ_000187"
     CDS             complement(44191..44676)
                     /locus_tag="ACL3EZ_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000847073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LURP-one-related/scramblase family protein"
                     /protein_id="HGR0391835.1"
                     /translation="MKTFLVKQKFRLGGERFAIKNDRGEIAYQVEGSFFKIPKTFTIY
                     DAAGEQVSEISKEILTLLPRFEIQLRDGSSFVIRKKLTFWRDKYEFDNLGLRIEGNIW
                     DLNFKLLDDRDQLIAEIKKELFHLTSTYTVTVLEDAYADLVISLCVAIDYVEMLESQS
                     H"
     gene            complement(44951..45190)
                     /locus_tag="ACL3EZ_000188"
     CDS             complement(44951..45190)
                     /locus_tag="ACL3EZ_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000784186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0391836.1"
                     /translation="MKMSTFFKKSFWPTFMIVNQTVILFHLKDGLDRQYLTTESIYWV
                     IGTFIFGNILVAVFSNMKIWDKKKNGSKKKYILKK"
     gene            complement(45451..46521)
                     /locus_tag="ACL3EZ_000189"
     CDS             complement(45451..46521)
                     /locus_tag="ACL3EZ_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGR0391837.1"
                     /translation="MKKIYSFLAGIAAIILVLWGIATHLDSKINSRDSQKLVIYNWGD
                     YIDPELLTQFTEETGIQVQYETFDSNEAMYTKIKQGGTTYDIAIPSEYMINKMKDEDL
                     LVPLDYSKIKGIENIGPEFLNQSFDPGNKFSIPYFWGTLGIVYNETMVDEAPEHWDDL
                     WKPEYKNSIMLFDGAREVLGLGLNSLGYSLNSKDLQQLEETVDKLYKLTPNIKAIVAD
                     EMKGYMIQNNVAIGVTFSGEASQMLEKNENLRYVVPTEASNLWFDNMVIPKTVKNQNS
                     AYAFINFMLKPENALQNAEYVGYSTPNLPAKELLPEETKEDKAFYPDVETMKHLEVYE
                     KFDHKWTGKYSDLFLQFKMYRK"
     gene            complement(46518..47291)
                     /locus_tag="ACL3EZ_000190"
     CDS             complement(46518..47291)
                     /locus_tag="ACL3EZ_000190"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0391838.1"
                     /translation="MKKFANLYLGLVFLVLYLPIFYLIGYAFNAGDDMNSFTGFSWTH
                     FETMFGDGRLMLILAQTFFLAFLSALIATIIGTFGAIYIYQSRKKYQEAFLSLNNILM
                     VAPDVMIGASFLILFTQLKFSLGFLTVLSSHVAFSIPIVVLMVLPRLKEMNGDMIHAA
                     YDLGASQFQMFKEIMLPYLTPSIIAGYFMAFTYSLDDFAVTFFVTGNGFSTLSVEIYS
                     RARKGISLEINALSALVFLFSIILVVGYYFISREKEEQA"
     gene            complement(47288..48094)
                     /locus_tag="ACL3EZ_000191"
     CDS             complement(47288..48094)
                     /locus_tag="ACL3EZ_000191"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0391839.1"
                     /translation="MKKTSSKLFVVPYMLWIALFVLAPLVLIFGQSFFNIEGQFSLEN
                     YKSYFASQNLTYLKMSFNSVLYAGIVTFVTLLISYPTALFLTRLKHRQLWLMLIILPT
                     WINLLLKAYAFIGIFGQNGSINQFLEFIGIGSQQLLFTDFSFIFVASYIELPFMILPI
                     FNVLDDMDNNLINASYDLGATKWETFRHVIFPLSMNGVRSGVQSVFIPSLSLFMLTRL
                     IGGNRVITLGTAIEQNFLTNDNYGMGSTIGVILILTMFITMWVTKERRER"
     gene            complement(48075..49232)
                     /locus_tag="ACL3EZ_000192"
     CDS             complement(48075..49232)
                     /locus_tag="ACL3EZ_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018372333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0391840.1"
                     /translation="MKKPIIEFKNVSKVFEDSNTKVLKDINFELEEGKFYTLLGASGS
                     GKSTILNIIAGLLDATTGDIMLDGVRINDIPTNKRDVHTVFQSYALFPHMNVFENVAF
                     PLRLRKIDKKEIEQRVAEVLKMVQLEGYEKRSIRKLSGGQRQRVAIARAIINQPRVVL
                     LDEPLSALDLKLRTDMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNDGEIVQ
                     SGTPVDIYDEPINHFVATFIGESNILPGTMIEDYLVEFNGKRFEAVDGGMKPNEPVEV
                     VIRPEDLRITLPEEGKLQVKVDTQLFRGVHYEIIAYDELGNEWMIHSTRKAIVGEEIG
                     LDFESEDIHIMRLNETEEEFDARIEEYVEIEEQEAGLINAIEEERDEENKL"
     gene            complement(49392..50297)
                     /gene="murB"
                     /locus_tag="ACL3EZ_000193"
     CDS             complement(49392..50297)
                     /gene="murB"
                     /locus_tag="ACL3EZ_000193"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000116193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008762 - UDP-N-acetylmuramate
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HGR0391841.1"
                     /translation="MSVREKMLEILEGIDIRFKEPLHSYSYTKVGGEADYLVFPRNRF
                     ELARLVKFANQENIPWMVLGNASNIIVRDGGIRGFVILCDKLNNVSVDGYTIEAEAGA
                     NLIETTRIALRHSLTGFEFACGIPGSVGGAVFMNAGAYGGEIAHILQSCKVLTKDGEI
                     ETLSAKDLAFGYRHSAIQESGAVVLSVKFALAPGTHQVIKQEMDRLTHLRELKQPLEY
                     PSCGSVFKRPVGHFAGQLISEAGLKGYRIGGVEVSEKHAGFMINVADGTAKDYEDLIQ
                     SVIEKVKEHSGITLEREVRILGESK"
     gene            complement(50409..51161)
                     /locus_tag="ACL3EZ_000194"
     CDS             complement(50409..51161)
                     /locus_tag="ACL3EZ_000194"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YhfC family glutamic-type intramembrane
                     protease"
                     /protein_id="HGR0391842.1"
                     /translation="MTIHIIITMLLLLAFLIGSIWFAKKKYQINLAVLGLGAVAFFVS
                     SQILEKLVHILILHPQKDGSIALLQDHPLIYIIYGLAMAAFFEETARLVFFKWLEKKR
                     SLEKADALAYGLGHGGLELIFLGLISLLNLYIVLSAVQTQNPQVMQLLSENMLKTIQS
                     LSVWQIYLLGFERILALGFQLLLTVWVYQAVRQKKWIYLLAAYGLHAFFDLAPSLFQV
                     GWLTNPVLVEVILALELVLVAYGTKEIFCKKS"
     gene            complement(51171..51902)
                     /gene="budA"
                     /locus_tag="ACL3EZ_000195"
     CDS             complement(51171..51902)
                     /gene="budA"
                     /locus_tag="ACL3EZ_000195"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047605 - acetolactate decarboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0045151 - acetoin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HGR0391843.1"
                     /translation="MDKNVQEPVKLFQYNTLGALMAGLYGGTMTVGELLEHGDLGLGT
                     LDSIDGELIVLDGKAYQAKGSGDQPEIVEVSPDALIPYAAVVPHQAEVIFRQRFEMTD
                     KELKERIESYYDGENLFRSIKIRGEFSHMHVRMIPKSTPDTKFADVATHQPEYSRDNV
                     AGTIVGFWTPEIFHGVSVAGYHLHFISDDLTFGGHVMDFVIKEGIIEVGAVDQLDQRF
                     PVQDRQYLFAKFNVDEMKKDIEKAE"
     gene            52044..53315
                     /locus_tag="ACL3EZ_000196"
     CDS             52044..53315
                     /locus_tag="ACL3EZ_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HGR0391844.1"
                     /translation="MKKQSKYKEVVSYLKNGIESGRFPTGSRLPSIRQLSLDFHCSKD
                     TIQRALLELRHEQYLYAKPQSGYYVLEQGQHQDLEIEVTDEHASAYDDFRLCVNETLI
                     GRENYLFNYYDNQEGLEDLRQSIHKLLFEQALYCKANQLVLTSGTQQALFILSQISFP
                     SQAKEILVEQPTYHRMNRLLIAQGLDYQTIERGIDGIDLKELERHFKTGKIKFFYTIP
                     RFHYPLGHSYSEQDKRSILNLAAKYDVYIVEDDYLGDLDSKKGQTFHYLDTEEHVIYI
                     KSFSTSLFPALRITALILPNAIKEAFVAYKNILDYDSNLIMQKALSLYIDSQLFEKNR
                     LARLTNHESYQKQIEERITKTPCPLPHYPLHDGLLLDLRQYPKIASLKHSQPGLDFFE
                     EAYLSTCPYQFAKVSLDNLENVLNYLKAELE"
     gene            complement(53335..54150)
                     /locus_tag="ACL3EZ_000197"
     CDS             complement(53335..54150)
                     /locus_tag="ACL3EZ_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGR0391845.1"
                     /translation="MKSKKWIFVLCNFLASFFLVACQSGSNGSQSAVEAIKQKGKLVV
                     ATSPDYAPFEFQSLVDGKNQVVGADIDMAQAIADELGVKLEISSMSFDNVLTSLQTGK
                     ADLAVAGISATDERKEVFDFSIPYYENKISFLVRKADVEKYKDLTSLESANIAAQKGT
                     VPESMVKEQLPKAQLTSLTNMGEAVNELQAGKVDAVHMDEPVALSYAAKNAGLAVATV
                     SLKMKDGDANAVALRKNSDDLKEVVDKVIQKLKDEGIYQSYLEKAASLTEVEE"
     gene            complement(54307..54960)
                     /gene="phoU"
                     /locus_tag="ACL3EZ_000198"
     CDS             complement(54307..54960)
                     /gene="phoU"
                     /locus_tag="ACL3EZ_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000946475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA];
                     GO_process: GO:0030643 - intracellular phosphate ion
                     homeostasis [Evidence IEA];
                     GO_process: GO:0045936 - negative regulation of phosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HGR0391846.1"
                     /translation="MLRSQFEEDLEKLHNQFYAMGQEVLSQINRTVRAFVTHDRDLAK
                     EVIEDDAEVNEYEVKLEKKSFEMIALQQPVSQDLRTVLTVLKAVSDVERMGDHAVAIA
                     QATIRMKGEERIPAVEEEIKKMGREVKSVVEAALDLYLNGSVDDAYRVASMDEQINHY
                     FETIRDLATEEIKKNPEAIVTGRDYFQVISYLERIGDYAKNICEWVVYFETGKIVEL"
     gene            complement(54972..55730)
                     /gene="pstB"
                     /locus_tag="ACL3EZ_000199"
     CDS             complement(54972..55730)
                     /gene="pstB"
                     /locus_tag="ACL3EZ_000199"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HGR0391847.1"
                     /translation="MTDAILQVSDLSVYYNKKKALNSVSLSFQPKEITALIGPSGSGK
                     STLLKSLNRMGDLNPEVTTTGSVVYNGHNIYSPRTDTVELRKEIGMVFQQPNPFPMTI
                     YENVVYGLRINGIKDKQVLDEAVEKALQGASIWDEVKDRLYDSAIGLSGGQQQRVCVA
                     RVLATSPKIILLDEPTSALDPISAGKIEETLYGLKDKYTMLLVTRSMQQASRISDKTG
                     FFLDGDLIEFNDTKQMFLDPQHKETEDYITGKFG"
     gene            complement(55743..56546)
                     /gene="pstB"
                     /locus_tag="ACL3EZ_000200"
     CDS             complement(55743..56546)
                     /gene="pstB"
                     /locus_tag="ACL3EZ_000200"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HGR0391848.1"
                     /translation="MSTYNWDEKHILTFPEEKVALSTKDVHVYYGKNESIKGIDMQFE
                     RNKITALIGPSGSGKSTYLRSLNRMNDTIDIAKVTGQILYRGIDVNRPEINVYEMRKH
                     IGMVFQRPNPFAKSIYRNITFAHERAGVKDKQVLDEIVETSLRQAALWDQVKDDLHKS
                     ALTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKNFTIIIV
                     THNMQQAARASDYTGFFYLGDLIEYDKTATIFQNAKLQSTNDYVSGHFG"
     gene            complement(56557..57441)
                     /gene="pstA"
                     /locus_tag="ACL3EZ_000201"
     CDS             complement(56557..57441)
                     /gene="pstA"
                     /locus_tag="ACL3EZ_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009443446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HGR0391849.1"
                     /translation="MRAKKLDKLATAVLYTIASIIVTILASLILYILVRGLPHISWSF
                     LTGRSSAFQAGGGIGIQLYNSFFLLVITLIISVPLSMGAGIYLAEYAKKGPVTNFVRT
                     CIEILSSLPSVVVGLFGYLIFVVQFEYGFSIISGALALTVFNLPQMTRNVEDSLKHVH
                     HTQREAGLALGISRWETVVHVVIPEALPGIVTGVVLASGRIFGEAAALIYTAGQSAPA
                     LDWSNWNILSVTSPISIFRQAETLAVHIWKVNSEGTIPDGTIVSAGSAAVLLIFILIF
                     NFGARKFGIYLHKKLTAA"
     gene            complement(57431..58348)
                     /gene="pstC"
                     /locus_tag="ACL3EZ_000202"
     CDS             complement(57431..58348)
                     /gene="pstC"
                     /locus_tag="ACL3EZ_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HGR0391850.1"
                     /translation="MNQEELAKKMLLPSKNSRLEKLGKGLTFACLSLIVILVAMILVF
                     VAQKGLSTFFVNGVNIFDFLLGGTWNPSSKEFGALPMILGSFIVTILSALIATPFAIG
                     AAVFMTEVSPKGAKILQPAIELLVGIPSVVYGFIGLQVVVPFVRSVFGGTGFGILSGI
                     SVLFVMILPTVTFMTTDSLRAVPRYYREASFAMGATRWQTIWRVILKAARSGIFTAVV
                     FGMARAFGEALAIQMVVGNSAVIPTSLTTPAATLTSILTMGIGNTVMGTVNNNVLWSL
                     ALVLLLMSLVFNSVIKLITKERGKKNYAR"
     gene            complement(58348..59226)
                     /gene="pstS"
                     /locus_tag="ACL3EZ_000203"
     CDS             complement(58348..59226)
                     /gene="pstS"
                     /locus_tag="ACL3EZ_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HGR0391851.1"
                     /translation="MKKRKKLALSLIAFWLTACLVGCASWIDRGESITAVGSTALQPL
                     VEVAADEFGTIHVGKTVNVQGGGSGTGLSQVQSGAVDIGNSDVFAEEKDGIDASALVD
                     HKVAVAGLALIVNKEVDVDNLTTEQLRQIFIGEVTNWKEVGGKDLPISVINRAAGSGS
                     RATFDTVIMEGQSAMQSQEQDSNGAVKSIVSKSPGAISYLSLTYIDDSVKSMKLNGYD
                     LSPENISSNNWPLWSYEHMYTLGQPNELAAEFLNFVLSDETQEGIVKGLKYIPIKEMK
                     VEKDAAGTVTVLEGRQ"
     gene            complement(59800..61104)
                     /locus_tag="ACL3EZ_000204"
     CDS             complement(59800..61104)
                     /locus_tag="ACL3EZ_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001160253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HGR0391852.1"
                     /translation="MQFPEGFVEKYKEILGDEARDFLASFEEEAVSAFRVNPLKEEQL
                     SFSDAITQTPWGHYGKVSGKSPEHATGLVYSQEPAAQMVAQVAQPSPGMKVLDLAAAP
                     GGKSTQLAAYLAGEGLLVSNEISSKRAKILVENMERFGATNVVVTNESADRLVKVFKG
                     YFDLIVLDAPCSGEGMFRKQPDAMDYWSLDYPSQCASLQREILEDAVTMLAEGGRLVY
                     STCTWAPEENEEIVNWLLEEYDFDLLPVEHINGMVAGIDLPETARMYPHQFKGEGQFV
                     AHLQFKGNNPAPKFKASKSNLSREQVALWQEFAQNHLKVNLPGILQTFGDQLYLLPEL
                     LPDLGKLKIARNGLHLGTFKKKRFEPSFALGLALKPSQVEQSVEIGQEAFVKYAAGEI
                     VQLAESLPNGWYQVLVKGNGLGFAKVTGNVLKNYFPKGLRFK"
     gene            complement(61105..61878)
                     /locus_tag="ACL3EZ_000205"
     CDS             complement(61105..61878)
                     /locus_tag="ACL3EZ_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HGR0391853.1"
                     /translation="MESKFEFAKELVKKAGQYILDHMQEDLRVETKSSPTDLVTRLDK
                     EVQELLVGEILSRYPEDKICAEEGCLRASVQEGKVWVIDPIDGTNNFVAQQEDFAVMM
                     AYFENGQGQFGLIYDVVKGDCYHGGGEFPVCLNDRPLAPFKTKPLGDFLIAGNSGMLE
                     TNEWGLADLSRAVLGVRVYGSAAISFAKILSGRLLTYLTYLQPWDYAAASILGESLGY
                     RVVTLFGEAPDFQTRQPVMMVPLEMQEEIQSYIYERKRT"
     gene            complement(61868..62146)
                     /locus_tag="ACL3EZ_000206"
     CDS             complement(61868..62146)
                     /locus_tag="ACL3EZ_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HGR0391854.1"
                     /translation="MNKQYSYPLDLSWSTEELASVLSFFNDVEAAYEGKVEAKKLLDS
                     YKGFKAVVPSKSEEKRLGREFETVSGYSLYRAVQAAKEKGEGKISLGK"
     gene            complement(62146..62547)
                     /locus_tag="ACL3EZ_000207"
     CDS             complement(62146..62547)
                     /locus_tag="ACL3EZ_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007556665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HGR0391855.1"
                     /translation="MITLFLSPSCTSCRKAKAWLEKHKVPFVEHNIMTSPLTRKELQH
                     ILSLTENGTDDIISTRSKIFQKLNIDVESISVSELLHLIEQYPSLLRRPIIIDAKRMQ
                     IGFNEDEIRAFLPRSYRKQELKEARMRAGIS"
     gene            complement(62757..63374)
                     /locus_tag="ACL3EZ_000208"
     CDS             complement(62757..63374)
                     /locus_tag="ACL3EZ_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HGR0391856.1"
                     /translation="MKTKLTFWGSMLFLLSLSILLTIYLAWIFYPMEIQWLNLTNRVY
                     LKPETIQYNFHILMNYLTNPFSQVLQMPDFRSSAAGLHHFAVVKNLFHLVQLVALVTL
                     PSFYVFVNRIVKKDFLSLYRKSLLALVVLPVMIGLGGVLIGFDQFFTLFHQILFVGDD
                     TWLFDPAKDPVIMILPETFFLHAFLLFFALYESFFGYLCLKSRRK"
     gene            complement(63364..64137)
                     /locus_tag="ACL3EZ_000209"
     CDS             complement(63364..64137)
                     /locus_tag="ACL3EZ_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HGR0391857.1"
                     /translation="MKYKGYLIDLDGTIYKGKDRIPAGETFVHELQKRDIPYLFVTNN
                     TTRTPESVKEMLAQNFNIDTPLSTVYTATLATIDYMNDLGLEKTVYVVGEAGLKEAIK
                     AAGYVEDKEKPAYVVVGLDWQVDYEKFATATLAIQKGAHFIGTNPDLNIPTERGLLPG
                     AGSLITLLEVATRVKPVYIGKPNAIIMDKAVEHLGLEREELIMVGDNYLTDIRAGIDN
                     GIPTLLVTTGFTKAEEVAGLPIAPTHVVSSLAEWDFDEN"
     gene            complement(64148..64885)
                     /locus_tag="ACL3EZ_000210"
     CDS             complement(64148..64885)
                     /locus_tag="ACL3EZ_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000524807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016790 - thiolester hydrolase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-ACP thioesterase domain-containing protein"
                     /protein_id="HGR0391858.1"
                     /translation="MGLTYQMKMKIPFDMADMNGHIKLPDVILLSLQVSGMQSIELGV
                     SDKAILEEYNLVWIIVEYDIEVVRLPRFAEEITIETEALSYNRLFCYRRFTIYNEAEQ
                     ELIHMMATFVLMDRDSRKVHVVEPEIVAPYQSDFDKKLIRGPKYESLEEPISKDYHVR
                     FYDLDMNGHVNNSKYLDWIFELMGADFLTHYIPKKINLKYVKEVRPGGVITSAVERTG
                     LESKHEITSDGVINAQAIITWQEIKKA"
     gene            complement(64890..66020)
                     /gene="hemW"
                     /locus_tag="ACL3EZ_000211"
     CDS             complement(64890..66020)
                     /gene="hemW"
                     /locus_tag="ACL3EZ_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:0051989 - coproporphyrinogen dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006779 - porphyrin-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM family heme chaperone HemW"
                     /protein_id="HGR0391859.1"
                     /translation="MQKKPTSAYVHIPFCTQICYYCDFSKVFIKNQPVDSYLEHLLEE
                     FRSYDIEKLSTLYIGGGTPTALSAPQLEVLLNGLTKNLDLSVLEELTIEANPGDLDAD
                     KIAVLKNSAVNRVSLGVQTFDDKMLKKIGRSHLEKDIYENIDRLKLAGFDNISIDLIY
                     ALPGQTMEQVKENVAKAIGLDIPHMSLYSLILENHTVFMNRMRRGKLPLPKEELEAEM
                     FEYIIAELERAGFEHYEISNFSKPGFESRHNLMYWDNAEYYGIGAGASGYVNGVRYKN
                     HGPIRHYLSAVEEGNACITEDHLSQKEQMEEEMFLGLRKKSGVSMARFEEKFGQSFAG
                     LYGEIVRDLVQQGLMQIEGDHVRMTKRGLFLGDTVAERFILE"
     gene            complement(66104..66493)
                     /locus_tag="ACL3EZ_000212"
     CDS             complement(66104..66493)
                     /locus_tag="ACL3EZ_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HGR0391860.1"
                     /translation="MGKLSSILLGTVSGAALALFLTSDKGKQVCSQAQDFLDDLREDP
                     EYAKEQVCEKLTEVKEQATDFVLKTKEQVESGEITVDSILAQAKSYAFQATEASKNQL
                     NNLKEQWQEKAEALDDSEEIVIDITEE"
     gene            complement(66466..66892)
                     /locus_tag="ACL3EZ_000213"
                     /pseudo
     CDS             complement(66466..66892)
                     /locus_tag="ACL3EZ_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895042.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
     gene            complement(66893..67681)
                     /gene="lgt"
                     /locus_tag="ACL3EZ_000214"
     CDS             complement(66893..67681)
                     /gene="lgt"
                     /locus_tag="ACL3EZ_000214"
                     /EC_number="2.5.1.145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008961 -
                     phosphatidylglycerol-prolipoprotein diacylglyceryl
                     transferase activity [Evidence IEA];
                     GO_process: GO:0009249 - protein lipoylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HGR0391861.1"
                     /translation="MLDPIAIQLGPLAIRWYALCIVTGLILAVYLTMKEAPRKKIIPD
                     DILDFILVAFPLAILGARLYYVIFRFDYYSQNLGEIFAIWNGGLAIYGGLITGALVLY
                     IFADRKLINTWDFLDIAAPSVMIAQSLGRWGNFFNQEAYGATVDNLDYLPGFIRDQMY
                     IEGSYRQPTFLYESLWNLLGFALILIFRRKWKSLRRGHITAFYLIWYGFGRMVIEGMR
                     TDSLMFFGLRVSQWLSVVLIGLGIMIVIYQNRKKAPYYITEEEN"
     gene            complement(67674..68609)
                     /gene="hprK"
                     /locus_tag="ACL3EZ_000215"
     CDS             complement(67674..68609)
                     /gene="hprK"
                     /locus_tag="ACL3EZ_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006109 - regulation of carbohydrate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HPr(Ser) kinase/phosphatase"
                     /protein_id="HGR0391862.1"
                     /translation="MSVLVKEVIEKLRLDIVYGEPELLEKEINTADITRPGLEMTGYF
                     DYYTPERIQLLGMKEWSYLISMPSNSRYEVLKKMFLPETPAVIVARGLVVPEEMLKAA
                     RECKIAILTSRAATSRLSGELSSYLDSRLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
                     ETGLELVKRGHRLVADDRVDIFAKDEITLWGEPAEILKHLIEIRGVGIIDVMSLYGAS
                     AVKDSSQVQLAVYLENYDTHKTFDRLGNNAEELEVSGVAIPRIRIPVKTGRNISVVIE
                     AAAMNYRAKEMGFDATRLFDERLTSLIARNEVQNA"
     gene            complement(68739..68915)
                     /gene="rpsU"
                     /locus_tag="ACL3EZ_000216"
     CDS             complement(68739..68915)
                     /gene="rpsU"
                     /locus_tag="ACL3EZ_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HGR0391863.1"
                     /translation="MSKTVVRKNESLDDALRRFKRAVTKAGTLQETRKREFYEKPSVK
                     RKRKSEVARKRKKF"
     gene            complement(69055..69762)
                     /locus_tag="ACL3EZ_000217"
     CDS             complement(69055..69762)
                     /locus_tag="ACL3EZ_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HGR0391864.1"
                     /translation="MKVIKVENQVQGGKVAFEILKEKLANGAQTLGLATGSSPLEFYK
                     EIVESDLDFSNLTSVNLDEYVGLDGDNPQSYRYFMQENLFNQKPFKESFLPRGVKDNA
                     EAEVERYNQILADHPVDLQILGIGRNGHIGFNEPGTPFDSQTHLVELDQSTIEANARF
                     FAKIEDVPTQAISMGIKNILDAKSIILFAYGESKAEAIAGTVSGPVTENLPASSLQNH
                     PDVTIIADAEALSLLEK"
     gene            69913..70941
                     /gene="queA"
                     /locus_tag="ACL3EZ_000218"
     CDS             69913..70941
                     /gene="queA"
                     /locus_tag="ACL3EZ_000218"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HGR0391865.1"
                     /translation="MNTADFDFHLPEELIAQTPLEKRDASKLLIVNRETGEMQDKHFH
                     SIIDMLEPGDALVMNDTRVLPARLYGQKVETGGHVELLLLKNTSGDEWEVLAKPAKRL
                     KVGTRISFGDGRLSAVVTEELTHGGRIVRFEYQGIFLEVLESLGEMPLPPYIHEKLDD
                     RERYQTVYAKESGSAAAPTAGLHFTKELLAEIQAKGVHLVYLTLHVGLGTFRPVSVDN
                     LDEHEMHSEFYQLSEEAAATLRSVKENGGRVIAVGTTSIRTLETIGSKFDGQIQADSG
                     WTNIFIKPGYEWKVVDAFSTNFHLPKSTLVMLVSAFAGRELVLDAYHHAIQEHYRFFS
                     FGDAMFIY"
     gene            complement(71602..71991)
                     /locus_tag="ACL3EZ_000219"
     CDS             complement(71602..71991)
                     /locus_tag="ACL3EZ_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HGR0391866.1"
                     /translation="MVKRRIRRGTREPEKVVVPEQSSIPSYPVSVTSNQGTDVAVEPA
                     KAVAPTTDWKQENGMWYFYNTDGSMATGWVQVNGSWYYLNSNGSMKVNQWFQVGGKWY
                     YVNASGELAVNTSIDGYRVNDNGEWVR"
     gene            complement(72095..72751)
                     /locus_tag="ACL3EZ_000220"
     CDS             complement(72095..72751)
                     /locus_tag="ACL3EZ_000220"
                     /inference="COORDINATES: protein motif:HMM:NF019142.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HGR0391867.1"
                     /translation="MFRRNLNTSFVHAADGIQYVRDDTRDKEEGIEYDDADNGDIIVK
                     VATKPKVVTKKISSTRIRYEKDETKDRSENPVTIDGEDGYVTTTRTYDVNPETGYVTE
                     QVTVDRKEATDTVIKVPAKSKVEEVLVPFATKYEADNDLSAGQEQEITLGKNGKTVTT
                     ITYNVDGKSGQVTESTLSQKKTLKQELLKKEPSPKFLSKKFQSKQNISMAQLLIKVKK
                     "
     gene            complement(73451..74002)
                     /locus_tag="ACL3EZ_000221"
     CDS             complement(73451..74002)
                     /locus_tag="ACL3EZ_000221"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR0391868.1"
                     /translation="MKSIGTQILQTERLILRRFVESDAEAMFQNWASSAENLTYVTWD
                     PHPDVEITRNSICNWVASYTNLNYYKWAICLKENPEQVIGDISIVKIDEADLSCEIGY
                     VLGKAYWGNGMMTETLKAILDFCFTQAGFQKVRARYASLNPASGRVMEKAGMSYLQTI
                     VNGVERKGYLADLIYYGISREEC"
     gene            complement(74352..75176)
                     /gene="nadE"
                     /locus_tag="ACL3EZ_000222"
     CDS             complement(74352..75176)
                     /gene="nadE"
                     /locus_tag="ACL3EZ_000222"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003952 - NAD+ synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_function: GO:0004359 - glutaminase activity [Evidence
                     IEA];
                     GO_function: GO:0008795 - NAD+ synthase activity [Evidence
                     IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HGR0391869.1"
                     /translation="MSLQETIIQELGVKPVIDAQEEIRRSIDFLKRYLKKHPFLKTFV
                     LGISGGQDSTLAGRLAQLAMEELRAETGDDSYKFIAVRLPYGVQADEADAQKALAFIQ
                     PDVSLVVNIKESADAMTAAVEATGSPVSDFNKGNIKARCRMIAQYALAGSHSGAVIGT
                     DHAAENITGFFTKFGDGGADILPLYRLNKRQGKQLLQKLGAEPALYEKIPTADLEEDK
                     PGLADEVALGVTYAEIDDYLEGKTISPEAQATIENWWHKGQHKRHLPITVFDDFWE"
     gene            complement(75173..76633)
                     /locus_tag="ACL3EZ_000223"
     CDS             complement(75173..76633)
                     /locus_tag="ACL3EZ_000223"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004516 - nicotinate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HGR0391870.1"
                     /translation="MYPDDSLTLHTDLYQINMMQVYFDQGIHNKKAVFEVYFRQQPFK
                     NGYAVFAGLERIVNYLEDLRFSDSDIAYLESLGYHGAFLDYLRNFKLELTVRSAQEGD
                     LVFANEPIVQVEGPLAQCQLVETALLNIVNYQTLVATKAARIRSVIEDEPLMEFGTRR
                     AQEMDAAIWGTRAAVIGGANGTSNVRAGKLFDIPVLGTHAHALVQVYGNDYEAFKAYA
                     ATHKNCVFLVDTYDTLRIGVPAAIQVARELGDQINFMGVRIDSGDIAYISKKVRQQLD
                     EAGFTEAKIYASNDLDENTILNLKMQKAKIDVWGVGTKLITAYDQPALGAVYKIVAIE
                     DETGQMRNTIKLSNNAEKVSTPGKKQVWRITSREKGKSEGDYITYDGVDISDMTEIKM
                     FHPTYTYIKKTVRNFDAVPLLVDIFKEGILVYNLPSLTDIQDYARKEFDKLWDEYKRV
                     LNPQHYPVDLARDVWQDKMDLIDKMRKEALGEGEEE"
     gene            complement(76749..77237)
                     /locus_tag="ACL3EZ_000224"
     CDS             complement(76749..77237)
                     /locus_tag="ACL3EZ_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6773 family protein"
                     /protein_id="HGR0391871.1"
                     /translation="MKNRFYYYQLLDEREEQLFNKAGSESFYICIALSLLSYIISVLA
                     PSLFNSNMLLIVIIIGTFYFFNRARYLGVTYYSRFHFTILGCFFLTLAITALLMLQNY
                     QFNIEIYQHNPLNFKYLSAWVITYIIYLPWIFIGNLGLKSYGEWAQKKFEQDMDELES
                     GE"
     gene            complement(77227..77436)
                     /locus_tag="ACL3EZ_000225"
     CDS             complement(77227..77436)
                     /locus_tag="ACL3EZ_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGR0391872.1"
                     /translation="MAKNLKLKLARVERDLTQGQLAEAVGVTRQTIGLIEAGKYNPSL
                     SLCQSICRCLGKTLDQLFWEEEDEK"
     gene            complement(77822..78292)
                     /locus_tag="ACL3EZ_000226"
                     /pseudo
     CDS             complement(77822..78292)
                     /locus_tag="ACL3EZ_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773447.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(78317..79188)
                     /locus_tag="ACL3EZ_000227"
                     /pseudo
     CDS             complement(78317..79188)
                     /locus_tag="ACL3EZ_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220488.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(79545..80273)
                     /locus_tag="ACL3EZ_000228"
                     /pseudo
     CDS             complement(79545..80273)
                     /locus_tag="ACL3EZ_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase C-terminal
                     domain-containing protein"
     gene            complement(80533..80844)
                     /locus_tag="ACL3EZ_000229"
     CDS             complement(80533..80844)
                     /locus_tag="ACL3EZ_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CHY zinc finger protein"
                     /protein_id="HGR0391873.1"
                     /translation="MIEAQGFLVDKQTRCIHYHSKLDIIALQCYDCKKYYACYRCHDS
                     LENHPFEPYPLSLIQDKPILCGVCLKLLTYKQYKESLSCPFCFSRFNPGCQNHKERYF
                     K"
     gene            complement(80859..82145)
                     /locus_tag="ACL3EZ_000230"
     CDS             complement(80859..82145)
                     /locus_tag="ACL3EZ_000230"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:1901576 - obsolete organic substance
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HGR0391874.1"
                     /translation="MTKTLKRPEVLSPAGTLEKLKVAVQYGADAVFIGGQAYGLRSRA
                     GNFTFEQMEEGVQFAAKYGAKVYVAANMVMHEGNEAGAGEWFRKLRDIGIAAVIVSDP
                     ALIMIAATEAPGLEIHLSTQASATNYETLEFWKELGLTRVVLAREVSMEELAEIRKRT
                     DVEIEAFVHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYDLYDMPFGKERKSL
                     QGEIPEEFSMSAVDMSMIDHIPDMIENGVDSLKIEGRMKSIHYVSTVTNCYKAAVDAY
                     LESSEKFEAIKQDLVDEMWKVAQRELATGFYYGIPSENEQLFGARRKIPEYKFVAEVV
                     SYDDAAQTATIRQRNVINEGDQVEFYGPGFRHFETYIEDLHDAKGNKIDRAPNPMELL
                     TIKVPQPVQSGDMVRALKEGLINLYKEDGTSVTVRA"
     gene            82742..83326
                     /locus_tag="ACL3EZ_000231"
                     /pseudo
     CDS             82742..83326
                     /locus_tag="ACL3EZ_000231"
                     /inference="COORDINATES: protein motif:HMM:NF021048.4"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
     gene            83323..84501
                     /locus_tag="ACL3EZ_000232"
     CDS             83323..84501
                     /locus_tag="ACL3EZ_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000217311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HGR0391875.1"
                     /translation="MTVLKGDNLEILKTIESSSIDLIYMDPPFFTQKTQKLSNNKNIM
                     YSFEDTWTSIEDYKEFLSVRLEECKRVLKNSGSIFVHCDKIANHHIRLILDNIFGADM
                     FQSEIIWNYKRWSNSKKGLLNNHQNIYFYSKSKDFKFNTIFTEYSSTTNIDQILVERK
                     RDGNSKTIYKVDNNGNYILAKEKNGVPLSDVWNIPFLNPKAKERVGYPTQKPILLLEQ
                     IIKIATDKNDIVLDPFCGSGTTLVASKILNRNYMGIDLSEEAINITQQRLENVIKTSS
                     DLLNKGIEAYRTKTEEEENILKLLQAKIVQRNKGIDGFLPKHFQKKPIPIKIQKNNEC
                     LNESISLLQNAINSKKLDFGVVIKTHSDNLLFDFDTIPENIIVVDHFELTIEKWLSKS
                     "
     gene            complement(85027..86019)
                     /locus_tag="ACL3EZ_000233"
     CDS             complement(85027..86019)
                     /locus_tag="ACL3EZ_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000122906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGR0391876.1"
                     /translation="MSYYDFVKDYMKVDECKNNEKYSSAGHTFCWKKENSTYAEGLYW
                     FYEGGSFIIDIHDFFIKEEVVQNSTYSMSDYVSIYSSYIVSANGEKFNPYQTITANSL
                     CTFDFDNIKDDFVFLLHENCCYLAVSIGFKKELIEKHLASININPESFYSTLLQPNQI
                     ILTKALERVAMEILNCKMDAPAADFFFKAKANEWISIVIDTYLNRKKYKIEIDDDKAL
                     EDVARFLDDHFATNVNQGTLEKISKMSGTKLKNLFKEKYCQSITEYTQRKRMNVAETL
                     LLNTELPIKEIAESVGYSSASKFSIYYKRYKGKLPSEVRNLACKHHNFKCDYCD"
     gene            86179..87933
                     /locus_tag="ACL3EZ_000234"
     CDS             86179..87933
                     /locus_tag="ACL3EZ_000234"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0391877.1"
                     /translation="MKIYKKLFAYVQDKKYLGVLAIIFSAISALLTVYGYYLIYKFLD
                     KLIINSNLSGAESIALKSVITLTSGAIFYFVSGMFSHILGFRLETNLRKRGIDGLEKA
                     SFRFFDLNPSGQIRKIIDDNAAQTHQVVAHMIPDSSQAIITPVLVLALGFIVSIRVGI
                     ILLALTIIGGLILGAMMGEQEFMKIYQESLSKLSAETVEYVRGMQVVKIFKANVESFK
                     SFYKAIKDYSKYAYDYSLSCKRPYVLYQWLFFGLIAILIIPIVYFMTSLASAKVILLE
                     LIMILFLSGVLFVSFMRMMWYSMYISQGNYAVDTLEALYEDMQKDKLVHGNVNNFKNY
                     NIEFENVSFAYNDKAVIENLSFNLEEGKSYALVGSSGSGKSTVAKLISGFYNVNKGSI
                     KIGGIAISEYSDEALIKAISFVFQDSKLFKKSIYDNVALANKDATKDDVMRALKLAGC
                     DLILDKFPERENTIIGSKGVYLSGGEKQRIAIARAILKDSKIIIMDEASASIDPDNEF
                     ELQKAFKNLMKDKTVIMIAHRLSTIKDLDEIIVMDSGKIIERGSDKELMSKDTRYKSL
                     QEMFNSANEWRVSNERVL"
     gene            87917..89638
                     /locus_tag="ACL3EZ_000235"
     CDS             87917..89638
                     /locus_tag="ACL3EZ_000235"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019214631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0391878.1"
                     /translation="MKEFYKKRFALTDGGARNLSKATLASFFVYCINMLPAILLMIFA
                     QEVLENMGKSNGFYIVFSVLTLIAMYILLSIEYDKLYNTTYQESADLRIRTAENLSKL
                     PLSYFSKHDISDISQTIMADIEGIEHAMSHSIPKVGGMVLFFPLISVMMLAGNVKMGL
                     AVIIPSILSFIFIPLSKKYQVNGQNRYYDVLRKNSESFQENIEMQMEIKAYNLSKDIK
                     DDLYKKMEDSERVHLKAEVTTILTLSISSIFSFISLAVVIFVGVNLIINKEINSLYLI
                     GYLLAAMKIKDSLDASKEGLMEIFYLSPKIERLKEIQNQDLQEGDDYSLKKFDIDLKD
                     VEFAYNKDAKVLNGVSFKAKQGEVTALVGASGCGKTTILKLISRLYDYDKGQILIDGK
                     DIKEISTESLFDKVSIVFQDVVLFNQSIMENIRIGKQDASDEEVKRAAKLANCTDFIE
                     KMDKGFDTVIGENGAELSGGERQRLSIARAFLKDAPILILDEITASLDVNNEKKIQES
                     LNNLVKDKTVVIISHRMKSIENADKIVVLQNGRVESEGKHEELLQKSKIYKNLIEKTK
                     MAEEFIY"
     gene            89649..90233
                     /locus_tag="ACL3EZ_000236"
     CDS             89649..90233
                     /locus_tag="ACL3EZ_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000368966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HGR0391879.1"
                     /translation="MDNKKLKVKDLVSIGVFGVIYFAFMFGVGMMGLIPILFLIYPTV
                     LAIVAGTVVMLFMAKVQKPWALFIFGMISPLVMFAAGHTYVVVVLSLIVMIIAELIRK
                     IGNYNSFKYNMLSYAIFSTWICSSLMQMLLAKEKYMEWSLMTMGKDYVDVLEKLITYP
                     HMALVALGAFLGGILGAYIGKALLKKHFEKAGIV"
     gene            90233..90928
                     /locus_tag="ACL3EZ_000237"
     CDS             90233..90928
                     /locus_tag="ACL3EZ_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HGR0391880.1"
                     /translation="MPTFSSNAPFNPNPISKILVVFITGLTVMHSINIRFELAIVCLI
                     GILLYLNGYKKTLFKWIILCGILYSLPNFMVLSELNPIVKMFLSIPIVIRMFILPFMA
                     ASFMIKTSDVGAIISSMDKLKISKNVSIPIAVMFRFFPSFKEEKKNIKMAMRVRGISF
                     KNPVKYLEYVSMPLLIISSNISDDIAKAAETKAIENPIAKTRYIRVKIQLIDFVYVLA
                     VAGLIVGGLIWLK"
     gene            90916..92280
                     /locus_tag="ACL3EZ_000238"
     CDS             90916..92280
                     /locus_tag="ACL3EZ_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002837029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0391881.1"
                     /translation="MVEIKNLSLDYGEEHILDDISLSIAEGECVLFTGKSGNGKSSLI
                     NSINGLAVRYDNAKTKGEIIIDGKNIKNLELYQISMLVSTVFQNPKTYFFNVNTTLEL
                     LFYLENIGLAREEMDRRLKDMLKIFPIKNLLNRNIFNLSGGEKQILCIAASYIAGTKI
                     IVMDEPSSNLDIKSISVLAKMLKILKEKGISIIVAEHRIYYLMDIVDRVFLIDKGKLK
                     KTYTRSEFLKLDKNELNALSLRDKELSKLKVPYLKEGGEYQIKNLSYKFTDDECLSLK
                     DISFKLGKIYGIIGSNGRGKSTLLRCLIGLEKKSKEEIYFKGEKLSKKERLKNSSLVM
                     QDVNHQLFTDEVFNELRLGVKNFDEEKAKIILKDLGLDEFIERHPMSLSGGQKQRLAI
                     ASVMCKNSPFIFFDEPSSGMDYSNMIKISELINKYKTMDKIIFIVSHDIEFLNEVADE
                     IFEL"
     gene            complement(92962..94134)
                     /locus_tag="ACL3EZ_000239"
                     /pseudo
     CDS             complement(92962..94134)
                     /locus_tag="ACL3EZ_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013730289.1,RefSeq:WP_050084071.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(94115..94309)
                     /locus_tag="ACL3EZ_000240"
     CDS             complement(94115..94309)
                     /locus_tag="ACL3EZ_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGR0391882.1"
                     /translation="MKIIQQQSAIIDSLTNELSLLCEQVAYLTQKLSGKSSEKSVCPF
                     GQLNLFEEESPSEKDGDVPS"
     gene            complement(94479..94829)
                     /gene="tnpB"
                     /locus_tag="ACL3EZ_000241"
     CDS             complement(94479..94829)
                     /gene="tnpB"
                     /locus_tag="ACL3EZ_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="TnpB, as the term is used for proteins encoded by
                     IS66 family insertion elements, is considered an accessory
                     protein, since TnpC, encoded by a neighboring gene, is a
                     DDE family transposase; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HGR0391883.1"
                     /translation="MTIHLSSLGQVYLVCGKTDMRQGIDSLAYLVKTHFELDPFSGQV
                     FLFCGGRKDRFKALYWDGQGFWLLYKRFENGRLTWPSTEKDVKALTPEQVDWLMKGFS
                     ITPKINLSESRDFY"
     gene            complement(94810..94995)
                     /locus_tag="ACL3EZ_000242"
     CDS             complement(94810..94995)
                     /locus_tag="ACL3EZ_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001136123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0391884.1"
                     /translation="MPQPIVPVEIPQSRPFDSKKRNDILLKIRIGKLEVSFFQSLNLE
                     MVEQLLDKVLLYDNSSI"
     gene            complement(95280..96842)
                     /gene="guaA"
                     /locus_tag="ACL3EZ_000243"
     CDS             complement(95280..96842)
                     /gene="guaA"
                     /locus_tag="ACL3EZ_000243"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003922 - GMP synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016462 - pyrophosphatase activity
                     [Evidence IEA];
                     GO_process: GO:0006177 - GMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HGR0391885.1"
                     /translation="MSNISTDLQDVEKIIVLDYGSQYNQLISRRIREIGVFSELKSHK
                     ISAAEVREVNPVGIILSGGPNSVYEDGSFDIDPEIFELGIPILGICYGMQLLTHKLGG
                     KVVPAGDAGNREYGQSTLTHTPSALFESTPDEQTVLMSHGDAVTEIPADFVRTGTSAD
                     CPYAAIENPDKHIYGIQFHPEVRHSVYGNDILRNFALNICKAKGDWSMDNFIDMQIKK
                     ICETVGDKRVLLGLSGGVDSSVVGVLLQKAIGDQLICIFVDHGLLRKGEADQVMDMLG
                     GKFGLNIVKADAAKRFLDKLAGVSDPEQKRKIIGNEFVYVFDDEASKLKDVKFLAQGT
                     LYTDVIESGTDTAQTIKSHHNVGGLPEDMQFELIEPLNTLYKDEVRALGTELGMPDHI
                     VWRQPFPGPGLAIRVMGEITEEKLETVRESDAILREEIAKAGLDRDIWQYFTVNTGVR
                     SVGVMGDGRTYDYTIAIRAITSIDGMTADFAKIPWEVLQKISVRIVNEVDHVNRIVYD
                     ITSKPPATVEWE"
     gene            96984..97682
                     /locus_tag="ACL3EZ_000244"
     CDS             96984..97682
                     /locus_tag="ACL3EZ_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HGR0391886.1"
                     /translation="MLPAYIKIHDQIKKDIDEYRWAIGERLPSERDLAEQFAVSRMTL
                     RQAVSLLVEEGVLERRVGSGTFVSSTRVQEKMRGTTSFTEIVKSQGKVPSSQLISYKK
                     TIPNEQEVAKLGIFPTDNIIRMERVRYADQVPLVYEVASIPEKFIKDFKKEEITSHFF
                     QTLQKHGYRIGKSQQTIYARLAKEKIAHYLEVEKGHAILGLTQVSYLEDGTAFEYVKS
                     QYVGERFEFYLENN"
     gene            complement(97725..98621)
                     /locus_tag="ACL3EZ_000245"
     CDS             complement(97725..98621)
                     /locus_tag="ACL3EZ_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HGR0391887.1"
                     /translation="MSNSLKGTLLTVVAGIAWGLSGTSGQYLMAHGISALVLTNLRLL
                     IAGGILMLLAYATAKDKILVFLKDRKSLLSLLIFALIGLFLNQFAYLSAIQETNAGTA
                     TVLQYVCPVGILIYSCIKDRVAPTLGEIVSIIFAIGGTFLIATHGQLDQLSMTPAGLF
                     WGLFSALTYALYIILPIALIKKWGSSLVIGVGMVIAGLVALPFTGILQADIPTSLDFL
                     LAFAGIILIGTVFAYTAFLKGASLIGPVKSSLLASIEPISAVFFAFLIMNEQFYPIDF
                     IGMAMILFAVTLISLKDLFLEK"
     gene            complement(98630..99565)
                     /locus_tag="ACL3EZ_000246"
     CDS             complement(98630..99565)
                     /locus_tag="ACL3EZ_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase domain-containing protein"
                     /protein_id="HGR0391888.1"
                     /translation="MKWTKIIKKIEEQIEAGIYPGASFAYFKDNQWTEFYLGQSDPEH
                     GLQTEAGLVYDLASVSKVVGVGTVCTFLWEIGQLDIDRLVIDFLPESDYPDITIRQLL
                     THATDLDPFIPNRDLLTAPELKEAMFHLNRRSQPAFLYSDVHFLLLGFILERIFNQDL
                     DVILKDQVWKPWGMTETKFGPVELAVPTVRGVEAGIVHDPKARLLGRHAGSAGLFSTI
                     KDLQIFLEHYLADDFARDLNQNFSPLDDKERSLAWNLEGDWLDHTGYTGTFIMWNRQK
                     QEATIFLSNRTYEKDERAQWILDRNQVMNLIRKEE"
     gene            complement(99562..100287)
                     /locus_tag="ACL3EZ_000247"
     CDS             complement(99562..100287)
                     /locus_tag="ACL3EZ_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001102210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CppA family protein"
                     /protein_id="HGR0391889.1"
                     /translation="MNVNQIVRIIPTLKANNRKLNETFYIETLGMKALLEESAFLSLG
                     DQTGLEKLVLEEAPSMRTRKVEGRKKLARLIVKVENPLEIEGILSKTDSIHRLYKGQN
                     GYAFEIFSPEDDLILIHAEDDRASLVEVGEKPEFQTDLASISLSKFEISMELHLPTDI
                     ESFLESSEIGASLDFIPAQGQDLTVDNTVTWDLSMLKFLVNELDIASLRQKFESIEYF
                     IPKSEKFFLGKDRNNVELWFEEV"
     gene            complement(100371..101006)
                     /locus_tag="ACL3EZ_000248"
     CDS             complement(100371..101006)
                     /locus_tag="ACL3EZ_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HGR0391890.1"
                     /translation="MAVQLLENWLLKEQEKIQTKYRHLNHISVVEPNILFIGDSIVEY
                     YPLQELFGTSKTIVNRGIRGYQTGLLLENLDAHLYGGAVDKIFLLIGTNDIGKDVPVN
                     EALNNLEAIIQSVARDYPLTEIKLLSILPVNEREEYQQAVYIRSNEKIQNWNQAYQEL
                     ASAYMQVEFVPVFDCLTDQAGQLKKEYTTDGLHLSIAGYQALSKALKDYLY"
     gene            complement(101008..101835)
                     /locus_tag="ACL3EZ_000249"
     CDS             complement(101008..101835)
                     /locus_tag="ACL3EZ_000249"
                     /EC_number="3.-.-.-"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HGR0391891.1"
                     /translation="MMIKVIATDMDGTLLDARGQLDLPRLEKILDQLDQRGIRFVIAT
                     GNEIHRMRQLLSPLVDRVVLVVANGARIFENNELIQAQTWDDAIVNKALTHFKGRACQ
                     DQFVVTGIKGDFVKEGTIFTDLESFMTPEMIEKFYQRMQFVDELTSDLFGGVLKMSMV
                     VGEERLSSVLEEINALFDGRVRAVSSGYGCIDILQAGIHKAWGLEELLKRWDLKSQEI
                     MAFGDSENDVEMLEMAGIAYAMENADEKAKAVATALAPANSQGGVYQVLENWLEKGE"
     gene            complement(101857..102192)
                     /locus_tag="ACL3EZ_000250"
     CDS             complement(101857..102192)
                     /locus_tag="ACL3EZ_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="poly-gamma-glutamate biosynthesis protein"
                     /protein_id="HGR0391892.1"
                     /translation="MGNFISNQRIESMGDEENAKWTERGVLMDVTIKKKDGKTTIGTA
                     KAHPTWVNRTPKGTFSPEGYPLYHYQTYILEDFIEDGSHRDQLDEATKERIDTAYKEM
                     NEHVGLKWY"
     gene            complement(102193..102909)
                     /locus_tag="ACL3EZ_000251"
     CDS             complement(102193..102909)
                     /locus_tag="ACL3EZ_000251"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF021127.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0045227 - capsule polysaccharide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
                     /protein_id="HGR0391893.1"
                     /translation="MAHGDLLYHDGLFFSAKKEDGTYDFHENFEYVTPWLKQADLAIG
                     DFEGTINKDHYLAGYLLFNAPVEVMDAIKEAGYHVLDLAHNHILDSQIEGVISMADII
                     EKAGITPIGVYTHEPRAQAPLVIKEVNAIKVALLAYSYGFNGIEQYISQEDYNRYLSD
                     LNEDKIKAEVERAEKEADITIIMPQMGVEYRLEPTEEQKALYHKMIDWGADIIFGGHP
                     HVVEPSETVEKDGDKKLIVY"
     gene            103422..104033
                     /gene="def"
                     /locus_tag="ACL3EZ_000252"
     CDS             103422..104033
                     /gene="def"
                     /locus_tag="ACL3EZ_000252"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042586 - peptide deformylase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HGR0391894.1"
                     /translation="MSAIERITKAAHLIDMNDIIREGNPTLRTVAEEVTFPLSDQEII
                     LGEKMMQFLKHSQDPVMAEKMGLRGGVGLAAPQLDISKRIIAVLVPNIVEEGETPQEA
                     YDLEAIMYNPKIVSHSVQDAALGEGEGCLSVDRNVPGYVVRHARVTVDYFDKDGEKHR
                     IKLKGYNSIVVQHEIDHINGIMFYDRINEKDPFAVKDGLLILE"
     gene            104078..104806
                     /gene="rlmB"
                     /locus_tag="ACL3EZ_000253"
     CDS             104078..104806
                     /gene="rlmB"
                     /locus_tag="ACL3EZ_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HGR0391895.1"
                     /translation="MKTNDIVYGVHAVTEALLANTGNKLYLQEDLRGKNVEKVKELAT
                     EKKVSISWTSKKSLSEMTEGAVHQGFVLRVSEFAYSELDYILAKTRQEENPLLLILDG
                     LTDPHNLGSILRTADATNVSGVIIPKHRTVGVTPVVAKTATGAIEHVPIARVTNLSQT
                     LDKLKDEGFWTFGTDMNGTPCHKWNTKGKIALIIGNEGKGISSNIKKQVDEMITIPMN
                     GHVQSLNASVAAAILMYEVFRNRL"
     gene            complement(104845..105756)
                     /gene="trxB"
                     /locus_tag="ACL3EZ_000254"
     CDS             complement(104845..105756)
                     /gene="trxB"
                     /locus_tag="ACL3EZ_000254"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004791 - thioredoxin-disulfide reductase
                     (NADPH) activity [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA];
                     GO_process: GO:0019430 - removal of superoxide radicals
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HGR0391896.1"
                     /translation="MYDTIIIGAGPAGMTAALYAARSNLKVALIEGGLPGGQMNNTSD
                     IENYPGYANISGPELAEKMFEPLENLGVEHIYGYVENVEDHGDFKKVMTDDQTYETRT
                     VIVATGSKHRPLGVPGEEELNSRGVSYCAVCDGAFFRDQDLLVVGGGDSAVEEALFLT
                     RFAKTVTIVHRRDQLRAQKVLQDRAFANEKISFIWDSVVREIKGENRVESVVFENVKT
                     GQVTEQAFGGVFIYVGLDPLSDFVKELNIQDQAGWIVTNNHMKTAVDGIFAVGDVRLK
                     DLRQVTTAVGDGAIAGQEAYKFITEHS"
     gene            complement(105822..106046)
                     /locus_tag="ACL3EZ_000255"
     CDS             complement(105822..106046)
                     /locus_tag="ACL3EZ_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4059 family protein"
                     /protein_id="HGR0391897.1"
                     /translation="MLLQLFSLYFESLILTTILVLIFLGIWIGLRAMSGVDKTARARQ
                     AHLYDMIMIGVLVVPVLSFAVMSLILVFKA"
     gene            complement(106124..106867)
                     /locus_tag="ACL3EZ_000256"
     CDS             complement(106124..106867)
                     /locus_tag="ACL3EZ_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HGR0391898.1"
                     /translation="MIKISNLSKSFSGQTVLDHLNLDIQKGEVVALIGSSGAGKSTFL
                     RSLNYLETPDSGSIQIDGFSVDFSKITQEEILALRRKLSMVFQQFNLFERRTALDNVK
                     EGLVVVKKLSDQEATKIAKEELAKVGLSDRENHYPRHLSGGQKQRVALARALAMKPDV
                     LLLDEPTSALDPELVGEVEKSIADAAKSGQTMILVSHDMSFVAQVADKILFLDKGKII
                     ESGTPDEIIHTPKEERTKEFFASYKRTYI"
     gene            complement(106867..107667)
                     /locus_tag="ACL3EZ_000257"
     CDS             complement(106867..107667)
                     /locus_tag="ACL3EZ_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001103446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HGR0391899.1"
                     /translation="MNVTTILASDWYQNLMQLIPDGKLFSLRSVFDGIPRIVQQLPTT
                     IMLTIGGALFGLVLALLFAIVKINRVKILYPLQAFFVSFLKGTPILVQLMLTYYGIPL
                     ALKALNQQWGTGLNINAIPAAAFAIVAFAFNEAAYASETIRAAILSVNPGEIEAARSL
                     GMTRAQVYRRVIIPNAAVVATPTLINSLIGLTKGTSLAFSAGVVEVFAQAQILGGADY
                     RYFERFISVALVYWVVNIGIESLGRFIERKMAISAPDTVQTDVKGDLR"
     gene            complement(107825..108181)
                     /locus_tag="ACL3EZ_000258"
     CDS             complement(107825..108181)
                     /locus_tag="ACL3EZ_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HGR0391900.1"
                     /translation="MLEFIEYPKCSTCKKAKQELNQLGVDYKAVHIVEETPSQEVILN
                     WLETSGFELKQFFNTSGIKYRELGLKDKVGSLSNQEAAELLASDGMLLKRPILVENGT
                     VKQIGYRKSYEELGLK"
     gene            complement(108194..108706)
                     /locus_tag="ACL3EZ_000259"
     CDS             complement(108194..108706)
                     /locus_tag="ACL3EZ_000259"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001170346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003908 -
                     methylated-DNA-[protein]-cysteine S-methyltransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HGR0391901.1"
                     /translation="MQKKYVKILYSSPIGILSLVADDHYLYGIWVQEQKHFERGLGDE
                     TIEEVVSHPILDPVIACLDDYFKGKPQDLSNLLLAPIGTNFEKRVWDYLQGIPYGQTV
                     TYGQIAQDLQVASAQAIGGAVGRNPWSILVPCHRVLGAGKRLTGYAAGVEKKAWLLEH
                     EGVDFKDINK"
     gene            complement(108706..109200)
                     /locus_tag="ACL3EZ_000260"
     CDS             complement(108706..109200)
                     /locus_tag="ACL3EZ_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase family protein"
                     /protein_id="HGR0391902.1"
                     /translation="MEIRLAFPNEVDAIMQVMEDAKKCLADAGSDQWQNGYPNADVII
                     DDIISGQAYVALEEGELLAYAAVTKSPEEAYEAIYEGNWQAGESEYLVFHRIAVAADV
                     QGKGVAQTFLEGLIEGFDYLDFRSDTHAENKVMQHIFEKLGFKQVGKVPVDGERLAYQ
                     KLKK"
     gene            109335..109781
                     /locus_tag="ACL3EZ_000261"
     CDS             109335..109781
                     /locus_tag="ACL3EZ_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HGR0391903.1"
                     /translation="MKTTFSYPKWAEIPNIDLYLDQVLLYVNQVCAPISPNKDKGLTA
                     SMVNNYVKNGYLTKPDKKKYQRQQIARLIAITTLKSVFSIQEIAQTLNTLQTQASSDQ
                     LYDAFVDYMNQGIDPANPIIQTSCQTVKLYHQTLDLIDHTQEEVIQ"
     gene            109778..110425
                     /locus_tag="ACL3EZ_000262"
     CDS             109778..110425
                     /locus_tag="ACL3EZ_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001097995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HGR0391904.1"
                     /translation="MNTSLKLSKQLSFGEEIANSVTHAVGAVIMLILLPISSIYSYEA
                     HGFLSSIGVSIFVISLFLMFLSSTIYHSMAYGSTHKYVLRIIDHSMIYVAIAGSYTPV
                     VLTLMNNWFGYLIIVIQWGTTIFGILYKIFAKKVNEKFSLALYLIMGWLVLAIIPAII
                     SQTTPVFWSLMVTGGLCYTVGAGFYAKKKPYFHMIWHLFILAASALQYIAIVYYM"
     gene            complement(110446..111027)
                     /gene="pdxT"
                     /locus_tag="ACL3EZ_000263"
     CDS             complement(110446..111027)
                     /gene="pdxT"
                     /locus_tag="ACL3EZ_000263"
                     /EC_number="3.5.1.2"
                     /EC_number="4.3.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004359 - glutaminase activity [Evidence
                     IEA];
                     GO_function: GO:0016884 - carbon-nitrogen ligase activity,
                     with glutamine as amido-N-donor [Evidence IEA];
                     GO_process: GO:0042823 - pyridoxal phosphate biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase glutaminase
                     subunit PdxT"
                     /protein_id="HGR0391905.1"
                     /translation="MKIGILALQGAFAEHAKVLDQLGVESVELRNLDDFQQDQSDLSG
                     LILPGGESTTMGKLLRDQNMLLPIREAILSGLPVFGTCAGLILLAKEITSQKESHLGT
                     MDMVVERNAYGRQLGSFYTEAECKGVGKIPMTFIRGPIISSVGEGVEILATVNNQIVA
                     AQEKNMLVSSFHPELTDDVRLHQYFINMCKEKS"
     gene            complement(111028..111903)
                     /gene="pdxS"
                     /locus_tag="ACL3EZ_000264"
     CDS             complement(111028..111903)
                     /gene="pdxS"
                     /locus_tag="ACL3EZ_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012054698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0042819 - vitamin B6 biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0042823 - pyridoxal phosphate biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase lyase subunit
                     PdxS"
                     /protein_id="HGR0391906.1"
                     /translation="MTENRYELNKNLAQMLKGGVIMDVQNPEQARIAEAAGAAAVMAL
                     ERIPADIRAAGGVSRMSDPKMIKEIQEAVSIPVMAKVRIGHFVEAQILEAIEIDYIDE
                     SEVLSPADDRFHVDKKEFQVPFVCGAKDLGEALRRIAEGASMIRTKGEPGTGDIVQAV
                     RHMRMMNQEIRRIQNLREDELYVAAKDLQVPVELVQYVHEHGKLPVVNFAAGGVATPA
                     DAALMMQLGAEGVFVGSGIFKSGDPVKRASAIVKAVTNFRNPQILAQISEDLGEAMVG
                     INENEIQILMAERGK"
     gene            complement(112055..113434)
                     /gene="nox"
                     /locus_tag="ACL3EZ_000265"
     CDS             complement(112055..113434)
                     /gene="nox"
                     /locus_tag="ACL3EZ_000265"
                     /EC_number="1.6.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="H2O-forming NADH oxidase"
                     /protein_id="HGR0391907.1"
                     /translation="MSKIVVVGANHAGTACINTMLDNFGNENEIVVFDQNSNISFLGC
                     GMALWIGEQIDGAEGLFYSDKEKLEAKGAKVYMNSPVLSIDYDNKVVTAEVEGKEHKE
                     SYEKLIFATGSTPILPPIEGVEIVKGNREFKATLENVQFVKLYQNAEEVINKLSDKSQ
                     HLDRIAVVGGGYIGVELAEAFERLGKEVVLVDIVDTVLNGYYDKDFTQMMAKNLEDHN
                     IRLALGQTVKAIEGDGKVERLITDKESFDVDMVILAVGFRPNTALADGKIELFRNGAF
                     LVDKKQETSIPGVYAVGDCATVYDNARKDTSYIALASNAVRTGIVGAYNACGHELEGI
                     GVQGSNGISIYGLHMVSTGLTLEKAKAAGYNATETGFNDLQKPEFMKHDNHEVAIKIV
                     FDKDSREILGAQMVSHDIAISMGIHMFSLAIQEHVTIDKLALTDLFFLPHFNKPYNYI
                     TMAALTAEK"
     gene            113728..114651
                     /locus_tag="ACL3EZ_000266"
     CDS             113728..114651
                     /locus_tag="ACL3EZ_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0017013 - protein flavinylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HGR0391908.1"
                     /translation="MTLRSHSERLMGTTITISLVDEQADIFLQKSFDLLKELEYRFNA
                     NSQESELMEINYQAGIAPVTVHPDLFELISLGLEHSLALSSHLNISIGPLIQTWRIGF
                     SDAKVAQPQEIESVLPLINPHGIELDSSTSTVFLKQKGMKIDLGCLAKGYSADKVAQF
                     LRKEGVTSALINLGGNILTIGKNQARGDNPWQIGIQDPANPRGNHLMTIPVVNKSVVT
                     SGIYERHLTVDGQDYHHIFDSQTGYPVETELASLTIISDKSVDGEIWTTRLFGERPAS
                     ILWQVESLEGIEVILIDKEGHLSCSSGIPTL"
     gene            114711..115316
                     /locus_tag="ACL3EZ_000267"
     CDS             114711..115316
                     /locus_tag="ACL3EZ_000267"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008752 - FMN reductase (NAD(P)H) activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0052873 - FMN reductase (NADPH) activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent FMN reductase"
                     /protein_id="HGR0391909.1"
                     /translation="MLKLIAIVGTNSKRSTNRQLLQYMQKHFADKAEIELVEIKTIPV
                     FNKPADKQVPAEILEIAAKIEEADGVIIGTPEYDHSIPAVLMSALAWLSYGIYPLLNK
                     PIMITGASYGTLGSSRAQLQLRQILNAPEIKANVLPDEFLLSHSLQAFNPSGDLVDLD
                     VIKKLDAIFDDFRIFVKITEKLRNAQELLRKDAEDFDWENL"
     gene            115335..116579
                     /locus_tag="ACL3EZ_000268"
     CDS             115335..116579
                     /locus_tag="ACL3EZ_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000673688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HGR0391910.1"
                     /translation="MKFVGLVGSNYDQSYNRKLLEFIRRYFKLKFELEVLEIDEVPMF
                     NQDEKWDESFQLRYLYNKITRADGVIIATPEHNHTISASLKSVLEWLSYEVHPFENKP
                     VMIVGASYYDQGTSRAQVHLRKILDAPGVNAYTLPGNEFLLGKAKEAFDNNGNITNEG
                     TVKFLETCLDNFVKYVGVVSKLKKPKPIESEDLDCGKPIATTITEVDPDDPEWVEKVA
                     AFTGAVSGDTYVKLDHGILTVNQIDMFLKAMPFELTYADDNNQFLYYNNAHQDPDTMF
                     AKRVPPQSGSRMSTVHGSLPPARMKNVEWVIGTLRNGNQEYVRTIVPGSPAGVINTHN
                     YQAMYYPDGSYAGINEIVFNFQPWLDWYLKETGQRLVGGSGPFAPAAGGHGDADATSG
                     ASDSGDAGGHGGDADATAGASY"
     gene            complement(116802..117059)
                     /locus_tag="ACL3EZ_000269"
     CDS             complement(116802..117059)
                     /locus_tag="ACL3EZ_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002901318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HGR0391911.1"
                     /translation="MDPKKIARINELAKKKKTEGLTPEEKVEQAKLREEYIEGYRRAV
                     RHHIEGIKIVDEEGNDVTPEKLRQVQREKGLHGRSLDDPNS"
     gene            complement(117101..119137)
                     /gene="glyS"
                     /locus_tag="ACL3EZ_000270"
     CDS             complement(117101..119137)
                     /gene="glyS"
                     /locus_tag="ACL3EZ_000270"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004820 - glycine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006426 - glycyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HGR0391912.1"
                     /translation="MTKNLLVELGLEELPAYVVTPSEKQLGEKMAAFLKENRLSFEAI
                     QTFSTPRRLAVRVTGLSDKQSDLTEDFKGPAKKIALDSDGNFTKAAQGFVRGKGLTVE
                     DIEFREIKGEEYVYVTKEEVGQSVEAIVPGVVDVLKSLTFPVSMHWAGNSFEYIRPVH
                     TLTVLLDEQEFDLDFLDIKGSRVSRGHRFLGKETKIQSALSYEEDLRKQFVIADPCER
                     EQMIVDQIKEIEAKHGVRIEIDADLLNEVLNLVEYPTAFMGSFDAKYLEVPEEVLVTS
                     MKEHQRYFVVRDQDGKLLPNFISVRNGNAERLKNVIKGNEKVLVARLEDGEFFWREDQ
                     KLVISDLVEKLNNVTFHEKIGSLREHMIRTGQITVLLAEKASLSVDETVDLARAAAIY
                     KFDLLTGMVGEFDELQGIMGEKYTLLAGETPAVAAAIREHYMPTSAEGELPESKVGAV
                     LAIADKLDTILSFFSVGLIPSGSNDPYALRRATQGVVRILDAFGWHIAMDELIDSLYA
                     LKFDSLTYENKAEVMDFIKARVDKMMGSTPKDIKEAVLAGSNFVVADMLEAASALVEV
                     SKEEDFKPSVESLSRAFNLAEKAEGVATVDSALFENDQEKALAEAVETLVLSGPASQQ
                     LKQLFALSPVIDAFFENTMVMAEDQAVRQNRLAILSQLTKKAAKFACFNQINTK"
     gene            complement(119349..120266)
                     /gene="glyQ"
                     /locus_tag="ACL3EZ_000271"
     CDS             complement(119349..120266)
                     /gene="glyQ"
                     /locus_tag="ACL3EZ_000271"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018163989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004820 - glycine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006426 - glycyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HGR0391913.1"
                     /translation="MSKKLTFQEIILTLQQFWNDQGCMLMQAYDNEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLESLEK
                     LGINPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATGPVTAE
                     VTYGLERLASYIQEVDSVYDIEWADGVKYGEIFIQPEYEHSKYSFEISDQEMLLENFD
                     KFEKEAGRALEEGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRNLARVVA
                     KTFVAERKRLGYPLLDEETRAKLLAEDAE"
     gene            complement(120459..121220)
                     /locus_tag="ACL3EZ_000272"
     CDS             complement(120459..121220)
                     /locus_tag="ACL3EZ_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HGR0391914.1"
                     /translation="MDNLYLVKDDSQLATFRDFVVRNTEKLKDYQSFLKNELAVCDLP
                     QAVIWSDFNAATQIIRESAVPAYTNNRRMVMAPDLAVWKELYLYQLMDYECSQQTQAI
                     ESHYHSLSENFLLQIVGHELAHWSEHFLDDFDGYDSYIWFEEGMVEYISRKYFLTEEE
                     FQAEKICNQSLVELFQKKYGWHSLNDFGSSTYDKNYASIFYEYWRSFLTVDKLVENLG
                     SVQAVLDSYHLWANTEKTFPLLDWFVQQKLIEKEI"
     gene            complement(121493..122335)
                     /locus_tag="ACL3EZ_000273"
     CDS             complement(121493..122335)
                     /locus_tag="ACL3EZ_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HGR0391915.1"
                     /translation="MNTYQLNNGVEIPVLGFGTFKAKDGEEAYHAVLEALKAGYRHID
                     TAAIYQNEESVGQAIKDSGVPREEMFVTTKLWNSQQTYEQTRQALEKSIEKLGLDYLD
                     LYLIHWPNPKPLRENDAWKTRNAEVWRAMEDLYQEGKIRAIGVSNFLPHHLDALLETA
                     TIVPAVNQVRLAPGVYQDQVVAYCREKGILLEAWGPFGQGELFDSKQVQEIAANHGKS
                     IAQIALAWSLAEGFLPLPKSVTTSRIQANLDCFGIELSHEERENLKTIAVQSGAPRVD
                     DVDF"
     gene            complement(122449..123840)
                     /gene="pgdA"
                     /locus_tag="ACL3EZ_000274"
     CDS             complement(122449..123840)
                     /gene="pgdA"
                     /locus_tag="ACL3EZ_000274"
                     /EC_number="3.5.1.104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050119 - N-acetylglucosamine deacetylase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0042545 - cell wall modification [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan-N-acetylglucosamine deacetylase
                     PgdA"
                     /protein_id="HGR0391916.1"
                     /translation="MNKSRLGRGRHGKTRHVLLALIGILAISICLLGGFIAFKIYQQK
                     SFEQKIESLKKEKDDQLSEGNQKEHFRQGQAEVIAYYPLQGEKVISSVRELINQDVKD
                     KLESKDNLVFYYTEQEESGLKGVVNRNVTKQIYDLVAFKVEETEKTSLGKVHLTEDGQ
                     PFTLDQLFSDASKAKEQLIKELTPFIEDKKIEQDQSEQIVKNFSDQDLSAWNFDYKDS
                     QIILYPSPVLENLEEIALPVSAFFDVIQSSYLLEKDAALYQSYFDKKYQKVVALTFDD
                     GPNPATTPQVLETLAKYDIKATFFVLGKNVSGNEDLVKRIKSEGHVVGNHSWSHPILS
                     QLSLDEAKKQITDTEDVLTKVLGSSSKLMRPPYGAITDDIRNSLDLSFIMWDVDSLDW
                     KSKNEASILTEIQHQVANGSIVLMHDIHSPTVNALPRVIEYLKNQGYTFVTIPEMLNT
                     RLKAHELYYSRDE"
     gene            complement(124078..124542)
                     /locus_tag="ACL3EZ_000275"
                     /pseudo
     CDS             complement(124078..124542)
                     /locus_tag="ACL3EZ_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000603351.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
     gene            124696..125673
                     /locus_tag="ACL3EZ_000276"
     CDS             124696..125673
                     /locus_tag="ACL3EZ_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HGR0391917.1"
                     /translation="MLKLGVIGTGAISHHFIEAAHTSGEYQLVAIYSRKLETAATFAS
                     RYQNIQLFDQLEVFFKSSFDLVYIASPNSLHFAQAKAALSAGKHVILEKPAVTQPQEW
                     FDLIQTAEKNNCFIFEAARNYHEKAFTTIKNFLADKQVLGADFNYAKYSSKMPDLLTG
                     QTPNVFSNRFAGGALMDLGIYPLYAAVRLFGKANDATYHAQQLDNSIDLNGDGILFYP
                     DYQVHIKAGKNITSNLPCEIYTTDGTLTLNTIEHIRSAIFTDHQGNQVQLPIQQAPHT
                     MTEEVAAFAHMIQQPDLNLYQTWLYDAGSVHELLYTMRQTAGIRFEAEK"
     gene            125670..126752
                     /locus_tag="ACL3EZ_000277"
     CDS             125670..126752
                     /locus_tag="ACL3EZ_000277"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HGR0391918.1"
                     /translation="MKTKLPTEWQELSDQLGFQEFTPIQTQLFEPLLAGENLLGVSQT
                     GTGKTLAYLLPSLLRLQKKKAQQLLILAPNTELAGQIFDVCKTWAEAIGLTAQLFLSG
                     SSQKRQIERLKKGPEILIGTPGRIFELIKLKKIKMMNVETIILDEFDQLLDDSQIHFV
                     EKITHYAPRDHQLVYMSATTKFDQEKIVPNTRTIDLSDQKLDNIQHFYMQVDQRHRVD
                     ILRKLAHVEDFRGLVFFNSLSDLGNAEEKLQYRDILAVSLASDVNVKFRKVILEKFKD
                     NQLTLLLATDLLARGIDIDSLECVVNFDIPRDSETYTHRAGRTGRMGKEGYVITLVTH
                     PEEIKKLKKFASIREIVLKNQELYIK"
     gene            complement(126816..127408)
                     /locus_tag="ACL3EZ_000278"
                     /pseudo
     CDS             complement(126816..127408)
                     /locus_tag="ACL3EZ_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT        39040 a        27306 c        22693 g        38369 t
ORIGIN      
        1 gaggattctg ttccccccat ataagcacta acattccaac gtacacatat tggaacgaca
       61 tccataactt cagagaatcc ctaaagttta caatttaaat gaattaacaa ttttcccaac
      121 taaaagcact ccagttaccg caacggtttg tactgaatgt actaaatcgc attccatcaa
      181 cttcatctgt ttcgtcaact tgaacagata ctaattgaag atttaatact tcttctgcca
      241 tagctagctc ctcctattta aatttttggg attaagtact ttatccaccc tcattatatt
      301 ctctccacca gtaaaatgca agcaatgata caagatagat ttaactattt tatatagcga
      361 aaacttacaa atttttaaga aataattttt gcattcttaa agataaaata ggaactttta
      421 gtaataaata ttaaaataaa taaaataata gacactataa aatttggaag tattaacccc
      481 aaaagattca tatcatctat taaaatatcc tctaaagagt agtatattaa agccataatt
      541 ttaatgttaa gtaaaaatgc aattaatgaa gtaacaaatg tcaaaaatat agcctcacca
      601 actttaatct taaccatctg gtaattagaa gttcctaaaa tttcaaattg ctgaatctca
      661 atcctttctt gatgcgatga caaaaatgca attgaaataa tatttgcaag tactatcaaa
      721 attggtgctc ctacatagac aataaatgcc acttttagct ctaaatcact gtcatcttga
      781 aattgagata gtatattctg agaaatcatt tgaaaactag aaattagtaa tatagctcct
      841 gtaattgcag cactgataga ttttatataa ggcttacgat atagtaaatt ccacttcgaa
      901 acaatgaaca taaaattatt tctaaatata attatagaaa gtagtttgat aaaacatgac
      961 tgtataaaag gagataattg ataaataatc acaatatcta agattacaat attgaatatt
     1021 atctgggcct tcgctaaaat tgtgctatct tggaaaattt gttgcaaaga aagcaaccag
     1081 ataacactaa aaccagccaa tagcagtatt ctttttacta ttgaaagaac atgccttatt
     1141 ttagaactct tcctatttct aatcttcttg aacgtataaa agcaaccact tagaaaggct
     1201 aaaaatgaaa tcaacactac tgtaatgata catccaacag cactcgtttg aaattggata
     1261 tcaggtaata tattttcccc gaaaaagtat tgtaaaaaat aataataatt tgacgtaaca
     1321 aatatagagc atagatatgc aataaaacta ataatcgagg aaatgataaa aatctgtccc
     1381 cccacaagaa atgatagttg aaggagactt gctcccaaca cctccagaag ttcgtaatca
     1441 tctctaaaaa tttcaaccaa catatttatt atgttagaga gcacaaagaa taatgttact
     1501 cctccgaata ctatcggaaa cataaaaatt ggtttaggat ctggaagtcc gacaaatact
     1561 tgcgaattat tctcaacatt aattacccca ttaacagcca atcccataac taaactcgaa
     1621 acaaaaatta ctggtgaaac gcctaaccat tgtttcttat tatgtaaaaa ttgatagtaa
     1681 actaatctga gcatctctat tcctccgtag ttgattgtac ctctaagatt ttatacaact
     1741 cttccccgct aggtctatga agttctttga aaatttttcc atctttcaat attaatgcac
     1801 gatcagtttt cgaggccaat tctatatcgt gcgttaccat aattacacac ttacccgccc
     1861 ctactaactc tctcaataat tcaaaaatta cttcacgaga aacgctgtct aaagccccag
     1921 ttggctcatc agcaaatatt atatcactat cagcaataac cgctctagct atagcaacct
     1981 tctgttgttc tccaccagac agagttccaa caaaatcgtt taagccagca ttaaacttca
     2041 ttcttttgag taagttttct acatttttaa tagttaattt tttttgtgat aatcgcaaag
     2101 gaagtgctat attttctatt accggcaggg aaggtattaa attgtatgct tgaaatataa
     2161 aagatacttc gttacgtctt atacttgaca attttgcatt tctgatttta taggggttga
     2221 ttccatttaa aattacttcc ccacttgttg gttcaagcaa actagaaata cattttaata
     2281 aagttgactt tccagaacca ctaattccta gaatacttat aaattctcct ctcgaagcag
     2341 aaagagaaac atttttcagc acttgcaacg ttttattatt tcctagtaaa aattgatgat
     2401 acagcccttt cacttttaat atataatctt tatccatatt cttgcctcca atcacttaat
     2461 tttgaaaagt gttccatttt ccaatttata tatatcagtg tatctcttgt catttaagtc
     2521 ataatgatgt gaaacttcaa taaatgaaat acctaaattg aacagaatat catgtatgga
     2581 atttgaatta tcattatcta aattagctga tatttcgtca aataagtaca ctttattatt
     2641 tctaatcaga gctctagcta aagctatttt ttgtttttga cctccagaca aattactacc
     2701 attttcacca cattgataat ttagtatatc tatcttttct aattcttcat atagatttac
     2761 cttttttaac acctcaatta tctgatcatc tgaaaaatat tcattttgaa ataaagttac
     2821 gttctcacga atagtagtgt caaaaatata tggtgtctga tcaactgttg gtattgaatc
     2881 tgaactcttt ttcccatgtg ataacaaatt tacataacct ttttgtggct ttaaagaacc
     2941 attaattaaa tttaaaatcg ttgttttccc actaccagaa gttcctgtta ataataccct
     3001 aaatggtgac ttaaatgaga agtcaatact taatttattt tctggtgtaa tagaatatac
     3061 aacatctttc atgtgtatct catctattga tgaagtatac agtccgttat tatcatgttc
     3121 agcgtctata aaattcttct ctccacttaa gtattttaaa aacggtttcc ttaaatcttt
     3181 ggttgtattt atcttattta atgaataggc aattgattgt atcggcccta aaactttatc
     3241 gtttgctaag aaaataccta tcagttcact aaaagaaagg cttttatgat aaattacaaa
     3301 ataacatcct acaaccaagg gaactagaaa gcaaaaacct gaaattagta ctgcaaccaa
     3361 ttttgaaaga acctctgatc gtttcaaatt aaaagtagaa tcttctagtt tatccaactt
     3421 tttatccgac aaactaatta tttctttagt aacagaataa gattttaatg tcttaaaacc
     3481 attaaaaatt tcttttatta tgtgagtata ctctgcattg ctgttagagt actcattagc
     3541 tgaattagac aacatcttct tcataaagac aggtactata atcggcaatg ctgataatac
     3601 aataaatatt attgaaacta ggaagtttaa ataaagcata aaacttagag agacgatgaa
     3661 caacaatatt gaagaaatta tttcaaaaat ttgtctaaaa tagttttctt cgattaatct
     3721 caaatcattt gacaaaactg aaataataga tgagtaatct ttaaccattt cagaagaaag
     3781 atactgttct ctaaaatatc cttgtttaat ttttacattt atatctttcg ttattgatgc
     3841 ttccgttact tctaaatagt aatttgatat atagattgct gaccaaccca gaatacttat
     3901 agcaccaaat cttagaacgt cagaaaatga ggaagtctga tttaaactac ctgcatatac
     3961 aataattcct gagagcaaga caccattaaa cgaagataga aatattaaaa tccccattaa
     4021 tataagttta gtctttttta taaattttaa ataattcata agttattcct tcccacttct
     4081 tcaaagaaat aatttaaagt atcaatcatt aagagaacat ctgatggagt aaaacctcca
     4141 tgaccagctg ctttgtttaa atacaacaaa cttttaactc caatagaatt taatttcttt
     4201 gaccactcta tcacttcgtt attattaata tatgggtctt tctcacccaa aatattaact
     4261 ataacagtat ttgagtctcg tgccttttca atattttgca taggcgaata tgactttata
     4321 taagccttta cttcagggtc tctaatatct ccccactctg ctatttcggt cttagaaaga
     4381 ggatcatttg gattctgaag tgtatcataa ggatttataa atggcgaaaa taagagaatg
     4441 ctttgcaata aatttttttc ctcgttcaac accgcaccag caattattcc acctgcacta
     4501 gaagttatta aacctaatcg cttactgtca attacatcat tttcccttaa ataatttact
     4561 ccctcaataa aatctctgat agaattccat ttgtttaacg cctttcctga gcgataccat
     4621 tcaccaccca aatagcctcc acctcttaca tgaactatag cataaataaa acctgcatct
     4681 attatagata acataatttc atctaaatca gaattatcat tcttaccata agccccatag
     4741 acacttagaa tacatttttt tcttcttggg agctcatccg tatcttcact tttccaaaat
     4801 aaagaaatcg gtatgcttac atcataactg tcttttttag tccaaatcac cttagaaaaa
     4861 tatttagtat tattcgattt tatgatgggt ctttcaaatt cagtttttaa tgtattttct
     4921 attaaatcaa aactaagtat tttttcgtaa aaagttctcc tctctaaaaa cagaagaaca
     4981 cgatcagaaa atgaattttc ataaagtgtt gtcttttcat caaatgttat cttattaaca
     5041 ctcaactccc tcaaactatt atttttaaat gtagcaagat aaaagacgga attcgctgcg
     5101 tttgaacagt ctaaaaggat ataacgtcct atacagtgaa ctcttctagc cctatcttga
     5161 tatggtatag taatagaaac tctgtctccc gaagaagttt cccttagaat tagttgatct
     5221 ttcttttctt cagttgaaga gagcccaaga aagtactgtg ctttttctgt actaaataga
     5281 gcgatatctc taggtgttgg ggctaccgtt tctgtgtaag agtgtctaac aaaacccgtc
     5341 cggtcgaaac tgtatagaaa aatcctgcct ttctgaaagt ctactgactt tacaaaacaa
     5401 ttattgctat caatgtggac tatttttaat cgaaaagagc attcgttttc ttcaaacagt
     5461 tcctcttctg taaagctatc aaaagattta tagaataact tacttggcct cccgtactct
     5521 ttggagcgag tatacataac accgaattta cccaaataga acgaactttc tactgaaata
     5581 tcttcaatga taaataactc ttccatagta tattttttta ttccaattaa attagtgcta
     5641 cgcagtgagg atacaaccaa aactatataa ctctcatcag atgaaatcct aacatcctgt
     5701 aagatactat catctggcaa agtatatttt tccacatcaa agacaatttt aagtgaattt
     5761 gaattgtcta aactggaaga actaacctta ggaatccagt cattatcttc gacataccat
     5821 tcctttatta caccagtatt gggtatactc caattatcaa attggtacca atatcgccct
     5881 ctcctaaata tcaaagaatt ccattttttt aattcctgaa atgatgaaga gatagacctc
     5941 ttatagtgtg ttttttcctg tattgtattt aaaaatattt cattactctg attcacaagt
     6001 atgacccctt aataatggta tctaaatatt atatttgagg aagaatcgtc aatttattat
     6061 ccattattga taccaatcca attgcaacac ccgcaaatcc cgaagcaata tctgttgtta
     6121 tctttaaacc attatctccc gcaataacaa atccttcttc aattacacac aaatatctat
     6181 aaagttgttc aattaatttc ttttgtcctg aaaagttatc atcgatatca ctatatatat
     6241 tattagcaac ttcaagacca caaaatccgt taaataaacc tggtaataca caaaaaacta
     6301 catcagttgc cctctctaaa gaagttaaat attttaagta tttgcttgac aagatttctt
     6361 tatttctatt aataagtaaa agcaggccag cacttccagt tgctagatat ggtagtaatc
     6421 tatgaccttg gctgtactgc aatgaattat tactatctac tttataagca actaattctt
     6481 tatctacagc caattctaga ccatttttat agatacttta accagttaat ttataagctt
     6541 caccgaagag ccaagctacc cctgcgtgac catatagtaa tccaccaaaa ttctcataag
     6601 gatcattact ctgaacatca ctagcgccaa ctttacaaaa agtttctgga ttttctatat
     6661 aatttaaagt atattctcta agcctaatta gtatttcttc tcctagttta ttatcaattt
     6721 cccctttact aagaaaatac agtccaacca gtaaaattcc agcctgccca ctatataaat
     6781 ttttattttg tgaattctca aatatctcta taaaatgagt tgtaaaaagt tcaactgccc
     6841 gatctatctc cccaaattca taaatgagcc agattgtacc aattttacca tcaaaaagac
     6901 cagaaaggga cgatttctta aaattattta ctgcctcatt aataacctgt gttcgaatct
     6961 cataatagtc atcaaacttg aaatttttta ctttcttagc tagttgttga taactccaaa
     7021 ggatagctaa atctgaaaac gcaattcctt gattaaaatt cagaccataa taatgaactg
     7081 ggaagaatct tgattgaaat tctttacgcc actgtccata agttagcgta aaccctctca
     7141 ataattttat aataaaatct tgtatatctt gctcactctc gatagttcta atctcatgca
     7201 tgggttttaa aacttttttc ctggaaatat tctcaatctg tggacattta gaatctagat
     7261 atgacaataa actttctaca taatctatat gttctcttgt ataacccaaa gactcaaata
     7321 gtttttttcc ttctatcctg gtttgactta catagttgta tgtcaaatcc gatgtagtta
     7381 ctagtggcat gtataaataa tgagctattt gtctaatacc ataccaatct atctcactgg
     7441 gaagtgtttc tcgccatgct ctaaaaccag gggctgcaac tttatgtaca actttttcat
     7501 catttgaaaa gacagcctgt tcccagtcta ttatactaat ctcatcttca tccttaacca
     7561 agatatttcc taaatgtaaa tcttgatgat atacattttc agaatgaaac ttattcgtta
     7621 aatcgatgag tttttctact atctttgaaa ctctcaatag ataatctttg gtcttatcaa
     7681 caacttcata taaaggaaaa ttattggtaa cccatctatt tagtggaacg cccttcatat
     7741 gttcaattcc taagaaggtg tgctcccaga tcttaccgtg ccagtatatt ttaggcgtct
     7801 cactccattc atttagaatt tttagtgctt tgcactccga agctaatttc tctgaagaat
     7861 aagtaccatc aaatcctaga cctgtatacg gtctagcctc ttttaaaatt atttttttcc
     7921 catcttcttt tagcctagca ttatatatcc caccactgtt tgaaaatcta attgcattat
     7981 ctataataaa gggaaagtct ccctgttttt tatctttctt gtcaagccat ttattcaaaa
     8041 agtcaggggg cactatacct tttggaattt taaatactgg taaacgttca tctttaacaa
     8101 cttcatcgcc aacaattaat tcatcaatag caaccttctt ttcatcatcc cttgacggcc
     8161 taaacacacc atacctcaga tatattggtg cttcatccca acgtttatcg cttaaaatat
     8221 atggcccatt atattgcttt aaggcacttt ctaacctttg caaaaccgac tctaattcat
     8281 tttgatttgg ataacatgta ataaatttac cagaaaatcc tcgactaacc aatttcccgt
     8341 ttcgcatgat aaatttgtct tctgtactaa gatgtttaaa tggaattcgc atttcatggc
     8401 aaatttttgc tacatcttgt aacaattcgt gtgaactatt atactctgaa ctaatgtgta
     8461 ttttccaccc ttgtctttca acaaattttc caatagggta ttgataaacc cactcatcat
     8521 tattcattac ttcgtgccaa ttaaaaggca gacttactta gtactttatg ctagtatctg
     8581 tactataatc attattagtg aaaaagaaag gatgctccaa attgaaatta taatccataa
     8641 caaaatctcc aagaaattct atcaaactta atatatctat agctagacag acttattaaa
     8701 ataaaaaggg agaatccttt ggattccccc catataagca ctgacattcc aacgtgcaca
     8761 tattggaacg agatccataa ctccagagaa tccctaaagt ttacaattta aatgaattaa
     8821 caattttccc aactaaaagc actccagtta ccgcaacggt ttgtactgaa tgtactaaat
     8881 cgcattccat caacttcatc tgtttcgtca acttgaacag atactaattg aagatttaat
     8941 acttcttctg ccatagctaa ctcctcctat ttaaattttt gggattaagt gctttatcca
     9001 ccttcattat actctctcca gcagtaaaat gcaagcaatg atacaatgtt gtcacgtaga
     9061 aaataatgtt tccgtaactt ttcaaagtaa cttccatctc tctcccaaaa ctggaagtta
     9121 gttttagaag ttacctaaaa atcaggttac ctattttaaa aaagcagcaa actataaact
     9181 agtaggctcc acaccaaatg tagccccata ctgccccata agtccaattt gtagcgtaca
     9241 agccctaaaa acatccccag cgatacatac aaacaccaag ctataatggt tcctggatga
     9301 tgtgctaagg caaataaaac acttgtcaaa gcaactcgaa tatctaattt tctaaccaag
     9361 ttccataaaa tttctctata cagaaattct tcaaccatac tcgcattgat taaaaacaat
     9421 aaaaatgaaa accaaggaac ttgatgttga agtccaatta agtttgcttg attcgtgctt
     9481 tcttgcgcat ggattaggct aaaacataga cttataatca gtaggctaac gaatccaata
     9541 ccaagccatt tcatcctaga tttcatattt accttatgag cttgtttgcg ttggccatac
     9601 atccataaaa aagaaatgag tgacgaacca tagagaatct gtagtatagt taactcaccg
     9661 atacaaagaa atttcaataa gtatagagat accaatagga catttacttg ttggaatata
     9721 taaactggaa ttattctttt catagttacc tccgaaacac aaaaaaaggg gtagacaatc
     9781 tagtgtctac ccccgaaagt ttattaaaac aaaaatcctg ccaaagaatt tttggcagga
     9841 aaccaaatca atttatcagt ttctatcaat cgcttatcgc tctcaaagac tggtaaatag
     9901 ggattccgca atcaaattgc gatactctat tatttaagag taactgaagc tccagcttct
     9961 tccaatttag ctttgatttc ttcagcttct gcagttgcaa cgccttcttt aacaagtgct
    10021 ggtgcaccgt caacaagttc tttagcttct ttaagaccaa gaccagtgat ttcacgtaca
    10081 actttgataa caccaacttt tttgtcgcct gcagatgtca attcaacgtc gaatgaatct
    10141 ttagcagcac cagcatcagc agcatcagct gcagcaacag ctacaggagc agctgcagtt
    10201 acaccaaatt cttcttcgat agcttttaca aggtcgttca attcaaggat tgaagcttct
    10261 ttaatttcag caataatgtt ttcaatgttc aatgccattg ttatttcctc caaataagtt
    10321 ttaaatttta taatagtttt tttcgtagct aggctacgct atgtagctta agattaagcc
    10381 gcgtcttctt tgctttctgc aaccgctttg actgcaagag caacgttgcg cactggcgct
    10441 tgaagtacag aaaggagcat agaaagaagt ccttcgcggt ttggaagagt tgcaagtgca
    10501 agaatctctt ctttagatgc gacagcgcct tcgattgcac cacctttaat ttcaagtgct
    10561 tcagcgtttt tagaaaagtc gttcaagatt ttcgctggtg cgataacatc ttcattagaa
    10621 aatgctactg cagatggtcc aacaaataca gatgcaagat cttcaagacc agctttttca
    10681 gctgcacgac gcaagattga gtttttaata actttatact caacttcgct tccacgaagc
    10741 tcacgacgaa gaactgtatc ttgctcaact gtcaaaccac gagcgtctac aacgacgata
    10801 gatgcagcag ctttcatttt ttcagctact acgtcaacta gttccgcttt tttagcaata
    10861 attgcttcac tcattagtgt gttcacctcc gtaattattt tgcttgggga atttttcaaa
    10921 aagaaaaacg cgcccaaacc tagacacgaa agtacaatac gcttcttttt acatgatacg
    10981 ttttgtcctc ggtaggatat ttatgagtcg agctccccta ctgtcttagg cagttttttt
    11041 aaaccgtata taagtatagc atagtcaaaa aaagaatgca agatttttgc aaactttttt
    11101 taaaattttt cgtaattttt cttttaaagt tctactgtca ggacttgacc ttgcttaaca
    11161 acctgttctc cggcgatata aacatcatct acatcactag atttaactgc ataaaccagg
    11221 tgagacagca tattttcctg aggttggaga tgaattttcc cttgtggttg aatgaccaga
    11281 aaatctgctt gcttgccgac ttccagactt cctatctgat tttccattcc aaggacctta
    11341 gccccttcga ttgtcagtac cttgagagct gtttcgattg gaaactggct ggcatcccca
    11401 cttttcatct tctgaagaag agctgcagtc cttccttcct caaacatatc tagattgtta
    11461 ttggaagcaa ccgagtcagt cgcaattccg actgctactc ccgctttttg gagctggata
    11521 attggagcaa ttcctgatgc cagtttgagg ttactgatag gattgtgggc gatagccact
    11581 tgagaagatg ccaagcgttc aatttctctc tcgtttaatt cgaccccgtg agcaaagacg
    11641 gacggatgat ctaaataacc cagttcttca agaaaagcaa gggggcgttt gccgtatcgt
    11701 ttgaggataa ttcctgactc ctccttggtc tccgccacat ggacatggag cggaatattt
    11761 agctcttttg ccatttccaa actcgcttcc agcaagtctc tactgcagct atacggagaa
    11821 tgaggtgcta ccataacctt gaaatttgga tttttatatt ttaagatttc gtctatgatg
    11881 gatcgagttc tgcttatagt ctcagcagtt gtttctgtct ctgaagaaaa gagagtcgga
    11941 gaaaaataac aacgcatctt ggaagttttc accacctgat aaatttgctg gatatccaca
    12001 ccattgggat tatacatatc gttaaaggtt gttgttcctg actggagcat ctctgttagg
    12061 gcttctttga ccgcattggt agtcatgtcg ggagtaaact cagattctgc tggccagata
    12121 tagtcattga gccattcatg gagattgctg tcatctcgga tccctctcag gcctgtcatt
    12181 gcagaatggg tgtgacaatt gaccaaacca ggcataatcc aagctccctg atagtctata
    12241 atctgctcag cttgctctaa aaacgctggc ttatcttgac cgacatagac gatttgagaa
    12301 tccttgactg ctaagattcc atcaagataa acatggaaat cttgatcaca agtcacgata
    12361 tttacatgct gaaagacttt cattataggc tccttttcta aaagacaagt tgtactctct
    12421 tcaaaccact tcaaattcac tttgccgtag gtgtggttac tgacttcgtc agttctatct
    12481 gcaacctcaa aacagttttt tgagctgact tcgtcagttc tatctgcaac ctcaaaacag
    12541 tgttttgagc aacctacggc tagcttccta gtttgctctt tgattttcat tgagtattac
    12601 agtaaacaat ttttctagct attgtaacaa aaaagtcact cgaaggcaac ttttttcgtc
    12661 cataaacttt caaaagagaa tggcttattc agaactaaaa gccgcagctt tttgcatttg
    12721 gtaatactta ccctttctat ccatgagttc ttgatggtta ccatattcaa caatatcacc
    12781 atctactaag acaagaatta aatccgcatc ctgaatggtt gacaaacggt gagcaatgat
    12841 gaaacttgtg cggcccttca tgagttttgc aaaggcatcc tgtaccagca cttctgtccg
    12901 tgtatcaatg gaagaagttg cctcgtctaa gataagaatc tttggaatag ccagaaagac
    12961 tcgggctatg gtcaagagct gagcttggcc gacagagaga gattctccag cattttccaa
    13021 cttggtatcg tatccctgtg gcaactgttg gatgaaaaag tctgcattag ctgctttggc
    13081 agcagcaatt acttgctctc gactggcttc aggattgcca aaggcaatat tatcatgaat
    13141 ggtcccttgt gtgagccagg tttcttgaag caccatgcca aactgctgtc tcaatgatgc
    13201 tcgtgtataa tcataaatgg attgcccatc cagcaagata tctcccgagc taatgggata
    13261 aaaacgcata aggagattga taagagttga ttttccagca cctgtcggac caacgatggc
    13321 tatcttacta ccagctggaa tatcgataga caagtcctta atcaaaattt tttcaggatg
    13381 gtagccaaaa gagacatgtt taaaggaaat agctccctta acttggtcac tggtcaagac
    13441 ttccttacct gtttcagcca cttcagtgct atctaagact ccatagatac gctctacgca
    13501 agccagagca ctttgcaact cagctagcac tgaagaaata tcattaaagg gcttggtgta
    13561 ttgctgaaca tagttcaaaa aagtcactaa acgaccgacg gtcaaggttg aacccatcat
    13621 gatacgataa gctcctactc cagctaaaag ggcataaatg agtgcattta caaagcgagt
    13681 cgaaggattg accgttgaag aataaaagat ggctgactga gaatagcctg agtagttgtc
    13741 atgagcctca cgcaatcttt ggataaattc tgtttgagca ttgaaggact ggattatagt
    13801 ctgctggcta agcgattctt caatcaactg agtctgaatt cccctcgtct ctgtttgctt
    13861 ctggaagaga tgataggatc tcttggcaat aaagcgtgaa atcaccatgg acagtggcgt
    13921 caacagcaag actaagagag tcatgaggag atgaatttgg agcatggcta gaatactaac
    13981 caaaatcatc aaaacaccaa tgaaaaattg gttaaaaatc atggtcaagc cagctgccaa
    14041 ctgttcgatg tccgtggtta cacgactgac catctctcca ttgccttgcc gatccgcaaa
    14101 agcaatcggt aaccgatgga gtttatggat gattcgctct cgtaaatctc tggtataaga
    14161 gaagattaga cgattataga ggagaggatt ggcccattgt actagagtat ttcctattac
    14221 caccaagagc atctggagaa aaatctgcca aaaaactggt gatgaaccag ccactaggac
    14281 ttggtcaatg acctgcccaa tcagaatagg tagataaatt gataagccaa cttgggcaat
    14341 agttcctaga aaggctagga aaaggaggaa gggatggttt gctaaatcta cggctaaacg
    14401 tttgagcgtc tggtttacag tttgtcgttt cattctagtc ctcctttcca tgttgggatg
    14461 cattgatttc acgatagact tgactggatt tcatcaagtc atcgtgcttg ccaacagcta
    14521 gcaactcacc tttttccaag aggagaatct ggtcagccat ctgtaaagtc gaggttcgtt
    14581 gagagatcaa aattaagctc atgtttggaa aattttctct aatagctttc aagagcttgg
    14641 actcggtaat ggtgtccagt gctgaggtcg catcatctag gatgagaaac ggagcctggc
    14701 gcaagactgc tcgtgcgata gacagccttt gtttttgtcc acctgagaaa tttcgccctc
    14761 ctgcttcaac tagagcatcc aagagtcctt ccttatcact gacaaaatcc ttagcttgag
    14821 caatttccaa ggcttgccag agttcttgat cagtcacttc ttgatttaaa cctaaagtca
    14881 agttggaacg aatagttccc ttaaaaagtt cgaccttttg gggaacataa gcaatccaag
    14941 accgccactg ctctaaatta cgaggactag atccatctcg ataaaggtca atgctcccct
    15001 tatctattgg ataaagtcca agtaagagtt gcaccaagct tgacttacca gaacccgttc
    15061 ccccgatgat acctagaatt tgtccttgag tcatatcaaa ggaaatgtat ctcagagaag
    15121 gctgggccgc atcaggatag gtaaaagtca attcttggac ttgtaaaacc cgaccactgg
    15181 taacttgctt ttgttctaat tctgaatgga tgttttcggg agattccgca aagacctcct
    15241 cgattcgctt ggctgagata taggactggt tgagagaatt tatcaacatg gctagcttga
    15301 ccaattccac caaaatctgt aagaggtaat tgataagagc aatgagagca ccttgactga
    15361 gcactcctcc ttgaattgaa atatagcctt gccagataat aacgagaaga gttccattga
    15421 caatcagata ggtcagaggt gttaataaac tagaccagaa acctgtcttt tcttgtaatc
    15481 tagcataaac ttggttaagg gtttgaaaaa tctgtaactc tcgtttttct tgaccaaaag
    15541 cacgaataac ccgcatccct tgcaattgct ggcgcgtttc ctgaaccagt tggtccgttt
    15601 tctttctgag actactgtag agaggattga ccaatcgaga taaccctaca atgacaatgg
    15661 tcaaaatggc aaccatgact aagaaccaga aagtcaactc agctgagatt cgataagcca
    15721 taaaaatggc accaaaaacg ataatgggcg ctcgtaaaaa gagacgcagg aattgattga
    15781 taccagtctg aatctggtag gtatccgaag tcaagcgagt aaccaaacta gaagttgtca
    15841 gacggtctct gctgtccttt ggcaaggaaa gaatatgacg ataaagatcg tttgtcaatt
    15901 ccttagcaaa acctactgct gcctttgctg agtaaaattg agctatcaag gccactaaaa
    15961 cgccaattac tgcaaagata aggagcaggc caatctgcat ccagagatga ccttgatctc
    16021 cctgaggtaa agattggtca acaatcccag caatcaccat gggaaccaag agctcaaaaa
    16081 cagcttctaa cagcttgaac aagggggcta aaattgattc cttgatgtag ggtttgaagt
    16141 aagataatag gtgtttcata aatcccttct attcatattc tagaaatgaa gaaagtggga
    16201 agccccactc tctgttttat ttgtttaagt aaggcaatag atagccatat cctgcttttt
    16261 ccatctcatc cttggccaca aagcgtaaag aagcagaatt gatacagtaa cggaggccgc
    16321 ctaactcccg cggtccatct gtgaaaacat gacccaagtg agcactgcct gaacgagaac
    16381 gaacttcaat tcgctccatt ccatggctca gatccttgta ataatgaatc aactctttgg
    16441 aaatcggacg gctaaaactt ggccaaccac aacctgaagc aaacttatcc ttggcaaaaa
    16501 agagtggctc acctgtcgta atatctacat aaatcccctc ttcaaaggtt tggtcatagg
    16561 cattggtaaa tggagcctct gtagcagctt cttgtgtgac acgataagac tcttcagata
    16621 gactggcctt caacacctct tgactaggct tttcatagtt tgctgcatca atcaatggct
    16681 tatcagcatc ggtcacatcg atatgacagt aacctgaagg attcttcctg agatagtctt
    16741 ggtggtagtc ttcagccaga atgtagtggc gtaattgctc cacttctact gcaatctttc
    16801 gacccagcat gcgttcctgc tcctgcacca ctgtgtagat agctggcaaa tctgcttcat
    16861 cctgataata aatcccagtt cgatattggc ggccacggtc attcccttgt tgattgatag
    16921 atagaggatc gataactcgg aaataataaa gtaaaatctc tctgagtgac acttccttct
    16981 catcgtaaat cacttggacc gtttctgcat ggtctgtttc cttgatcaac tggtaattgg
    17041 tcgtttcgac ttgaccatta gcgtagccaa cactggtttc tagcactcca gaaatgcgtg
    17101 aaaaatattc ctctaggccc caaaaacaac cacctgctag ataaatttct gccatcttta
    17161 tttctccttt atcacgtttt taactaatac tcttcgaaaa tctcttcaaa ccacgttagc
    17221 gtcaccttac cgtatatatg ttactgactt cgtcagttct atctgcaacc tcaaaacagt
    17281 gtcttgagct gacttcgtca gttctatcca caacctcaaa acactgtttt gagcagcctg
    17341 cggctagctt cctagtttgc tctttgattt tcattgagta taaacttctt ttcacaaaaa
    17401 ggatatgaaa ccctctggtc aagagtttcc ccatcctatc ttctattctt tattttgctt
    17461 ctacacggac accttgggta tcaactctca agtcatgcag ttttcctttg aaaggttgct
    17521 tttccaattc tgccttaatt gttggcatct tgtcatgaga agccagaacc ataactgtcg
    17581 gcccagcacc agaaaggtag gttgcatagg ccccattttc tttggtcact tgcttaatca
    17641 tcgcaaattc tcttaccaag tcctgacgat agcgctcatg gaagaggtct ccctcgattg
    17701 cttgcccagc ggtcaccatg tctcctgcca acaaggcagc aaccgctaca ttggcgatag
    17761 aacttgcagc aacagcttcc ttataagaca attttttagg caagacacta cggctgtcgc
    17821 gagtacgtaa ttcatagttt ggaatgtaag ctagaaaatc acactctgga aagtctgcta
    17881 cgatagcaga gacttgccct tcaacagaac ttgcaataac gagattacca taaatggctg
    17941 gagccacatt gtcaggatgc ccttcaatct tggtcgctaa ctgcaatttt tcatggtctg
    18001 ataagttgag ttgacccagt tggttggcta gttcaatccc agcaacgata accgagctgg
    18061 aagaacccaa accgcgcgcc aaagggacat cactggtcat tttcaagcgt cttggttgca
    18121 agtctggtac aatttgcaaa gcgattttga gcaagagatt acgctcatca tgtggaatcc
    18181 atttgccaat ctggtgttca atcagccact catctcgttc ttcgcagacc tcaatttgaa
    18241 gatacttggt tacagctaca ccgaccgagt caaaacctgg cccgatattg gcactggttg
    18301 caggtacaat aatcttcatc ttattctcct agcaccttga aggtattcaa gaggtcgaat
    18361 tctgaaacct tcttcaattc agctgagaca ttttcaagct gggctttatt aatcttgtgt
    18421 gtgatgataa cgacacgcgc cttgtcaccc tctttgccat cttgaaggat ttgcttaaag
    18481 gaaatatctt gagcattgaa gatttcagcc aacttcaaga cctgaccttt tgagtctaga
    18541 gccaagattg agaaatagta gtttgctttg acatcttcag gatttgccaa gaccaagtca
    18601 cggctatatt cgttgaagtc tttgccaata gtaccatcat tcaaacgacg aacgatacgg
    18661 acaatatcag ctacaacact tgttgcagtt ggtttttgac ccgcacctgg tccgtagtac
    18721 atagactcac caataccgat agattctaca aagacagcgt tcattacgcc attcacacta
    18781 gcaagtgggt gcgctttagg taggaaggtt ggagtcactt ctgcagcaat acctgaagaa
    18841 gtttcctcaa tagaaccaac caatttcact acgtaaccaa gctcttgagc tacagctacg
    18901 tcttctggtg tgatattgcg gattcccttg tgggctacat catcaaaggc aatcttcatg
    18961 ccaaaggcaa attgactcaa aataaccatc ttgtaggctg catcaatccc atctacgtca
    19021 ttcgtcggat cgctttctgt aaatcctaga cgttgtgctt ccgcaagagc atcatcgtaa
    19081 gaccagcctt cttccaccat cttggtcacc atgaagttgg aagttccgtt gactactcca
    19141 agcacgcgcg taattttatc agaagccaag gaatttgcta aagtacgaag aattggaatc
    19201 ccaccagcaa ctgctgcttc gtagtaaagt gctaccttgt tagcttgagc gatttctagc
    19261 aattctgcgc catggacagc taaaaggtcc ttgttagcag taacaacgtg ttttccagct
    19321 tccaaggcac gagtgataaa ggttttagca ggctcaatac gccccatcaa ttccactacg
    19381 atagtaatat catggtctga taaaatatca tccacattgg ttacaaagtt aaagtcattc
    19441 cctgctgcaa gcaagcgatt tttttcatct tcatccttga ccaatacctt agcaactttg
    19501 atatctgaat gtgctgattg attgattttt cctccatttt cctttaggag gaaaggcaca
    19561 ccacttgcaa cggtaccaaa tcctagtaaa gcaattttaa ctgtcatctt tatctcctcg
    19621 aaattttcta atatagccat tataacagaa ttttgtgaaa attcctatta tagtaaatca
    19681 ctatttcagt ataaaaagaa aaaacgaatc agacgattcg ctcttcttaa aatctgaaaa
    19741 tagctttcca gaaaggatta gccgattttt tgcagattga gcactgcatc gtgactcatc
    19801 aagacttgac catactcttg taagactgag cgactgatat cactatcgtc tgcaaactcg
    19861 cgcatacggg ccaacagcca agctggatat gggcttggat gattttcaat atccactaaa
    19921 atggtcaaat aatagcgctc gttcattttg tagagttcag aagtttccat ttcaaaagtc
    19981 actgtcttgg caaaaactac caagtcagcc aacttagcaa aagaaaggat gtagtagatg
    20041 taaggttctt tcttactctc agcttcttgt tcagcctgct cttgctcttc ttccttggct
    20101 tcaacttgct caagagattg aatggcttcg atatcatcct tggttttgtc tgcgatgctt
    20161 ttttccaggg ttttgataaa ttcatctgga gacatttgag ccaattcttc catatctggc
    20221 aaatccgata agtcttcaaa atctagattt tggtcaatct ttgacttggt cacaaagaca
    20281 tctaccttat caggttttgg agtcacacgg aagctcaaca tgcctgtatc cagaaagcta
    20341 tcaggcatct ctagctcatc caagatagca taaaagaact cttctgtttt ttcttgagga
    20401 acgagaaagt cagcaatctc cattccacga tccatcaaat cctctaaaga catcgtgatt
    20461 tttaaagttg tatcactaat ttgtttcatt ttcattgcta gtaacctcat actttcagtt
    20521 ctatctatta tactagattt ttacgatttt atcaaaagaa ggctcctcta tacggataga
    20581 ttttccctag ggtctttcta taggagactc caaaagaaaa tttctgcaga cagatagaaa
    20641 aagccttcaa aatcagctct tagccgattt tgaagacctt atacatcaga atacttataa
    20701 tttaaaggtt gctacaccaa ggatagaacg atttaagttt ctgagaattt gaagactttg
    20761 ctcaaatttc ttataacgag tcactccgta ctcttcaaca agaaggactg tatctctttc
    20821 caaaagagat gatacatcct gtaaatctac aaaatgcatt ccttttaaag cttcttgact
    20881 ctgtttcaat ttatctagga tagctttatt tgagctaacg atggtcaatt cctgtccagt
    20941 atttttgtat gacaaaacat ctgctaggtt agcaattgtt gtaatctctg ttacaaaatc
    21001 aatttgatac tgagaaaaat cacctactct attgattgtt ggattaaaga gataaactaa
    21061 cacatttccc atcacaacca aaatcacaca aaccactcca ataacaacta aacgaagaat
    21121 cagatttttc acatttaagc caagcgctgt ttcaccattt gcgttcaatt ctttagagtt
    21181 gatggtttcc agtttttcaa ttttcacatt tgcataggca tgtttaaatt tctcaatcaa
    21241 cccatcaatt tttttctcta acaagtcatt ggcatcttta cttgatgtca aaattttcac
    21301 accaacccct gcatcgtcaa tcatatagta gacggtcaat tttttccacc aatagtcatt
    21361 cgttgaattt ttcaaggttg tttctgtcgt gtctaattca ctggcaattt ttttcaactc
    21421 actgggttct acatcattga aaagataagc tccattcaaa ttaccatcaa tcaatttccc
    21481 ataaaaatca ctataaccac caatttgatg attcaaaatc gttttggccg actcttttgg
    21541 aggagtgatt ttatagataa gataagttga ataacttgtt gtatctttga cagtgttttt
    21601 attcctaact gctttaattg taaatggtac agcaatgaga gcaaataaag cgatgagagc
    21661 taaaatattt gcttttcgct ttttataaag atttgcaaac aaatcagcta ctgaataatg
    21721 ttcaaacatg atttttttct cctttgttta gtagatacta gttttccttt gtaagcattt
    21781 ttgctacaaa tataatcaca agaacaattc cccagaattg cattgtaaat aaattgaaga
    21841 aactttctga aaagctgctt cttggcataa agaatagatt attcaagatg agtagggata
    21901 aagcaaatag gattgtcctt gagcgatagg ctacttgcag catggctata aataatacgc
    21961 cgagtaagaa actaagcaga aagactccaa tcataccata gtcggtatac aactccatga
    22021 tataactact tccgatacca tgccctttca agtattcctt gttcaagaca agataggata
    22081 gattgtgggc ataactatta ctatcaatag ctagttccac actattggtt gtatgttcaa
    22141 aggcttttcc tccgaaaatg gctcccaaac tcccccttgc aaaataatca agaacaggac
    22201 caaaagtaaa attacggaaa tctcggtaag ggaggctact gttaaataga aaacctcgag
    22261 ccagaacacc aaaactagtc ccttgtttat agataaagtc aagtaagata tcccagaaac
    22321 ctgtatgaga aacttggaca ttatcccgta cataattgag tactcccatc gctaacatga
    22381 gaataggaga acctacaaaa atcgctaact tttctttaaa cccaatccat tttccttttt
    22441 cagtttgctc ccgcataaag taataaacaa aagcaaataa aatacttaaa ataaagggat
    22501 ttcgtgtccc aattgccaaa tgaatagtat tagctgcaat aaaggagaca agcactgctg
    22561 tggcctgcaa tttctttggc ttggttgcca gatacataca cattgcatag accgtaaagg
    22621 tagacaaaat gtaggtaaaa taaggcagtt tactttcaaa atttgcatag taggcatagt
    22681 aggaagtctg caaacgatac aagagccgtt caaataaccg aatgaaatag aaaggatagg
    22741 ttagaagaaa aactcctagt gatacaaagc gtaaccgctt gatataaacc tcttttagag
    22801 aatttcctat atttgctact tttattttct tcctagctat gaagtaacga gccagaatgc
    22861 ctcctgtggt caagcccaga atcgaaacca tgacaactat aaaggcaaaa cgataggcta
    22921 ttggatgata ggtatccaaa gcaccatccc taaaataatc aatggtcggt cttgatacca
    22981 gaaatacaaa aatggttaaa tagaaaataa aatggattaa gtaatacttg atatcattcc
    23041 aacaagcaat taagctacta accaacaaga acaataaagt agaaagtaag ctaacattat
    23101 tattattaaa cagatacaca attccactta ctagcgtcaa ggcataactg actatggtca
    23161 aactaaataa taatcgtttc ccatcaatca cttggtcacc cccgttctaa tgtaattttt
    23221 tagatttttc aatatttttc agtaataaga atcgatataa ggaaatattt atgaataggg
    23281 ccaaagcact aattcttctc cccttacgga aaattggatt cctagaaata gcaaaggcat
    23341 ggccttttaa aaaacgatga atctgagaat aggcttcaaa ctgtttatac tgatcatcta
    23401 gcaacatctt atccagaata aagaagtggg cataggccaa tctgaaaaaa gcgacctctt
    23461 tcaagtcagg atagtttttc acaacttcat tataaaactt ttggtagata tcaatatagg
    23521 ctaaatcctt ctctgcatag ggtttggtcg taatactatc ccctctatgg aaatagtaat
    23581 aatagggttt agtattaacc acatacttct tggccaactt gattaaatca aaatggtaat
    23641 aggcatcttc gtaaatcaac cccttaggaa aggatagggc agttgcaatc tgtctcttga
    23701 ttagcttatt gcaaatcgtc ccaggtattt tttcacctat gaggtattcc tttagaaatg
    23761 tttgagaatc acagacaaaa tagtcatcct gattggctga ctgtgggctt tcatcattag
    23821 catagacatt catgacacca cagcttgaaa catccgcatc ttcttgaact aattgctcat
    23881 ataagctctg aatcatttct ggatggatat aatcatctga gtcaataaaa atcagataat
    23941 ccccgtgagc ctgcttcatc ccatcatttc gtgcttgcga caatccttcg ttctttttat
    24001 gaagcactga caccctgtca tcttgttcag cgattgaatc acacaagcga ccactttcat
    24061 ctgttgcacc atcatcaaca agaataattt ccagattttg ataggtctgc ttctgaatgg
    24121 aagctatcga tttttctagg tactgcgcca cattatagac tggcacaatc acactaatta
    24181 atgcagtttc catgctactc ctctaatagt ttttctactt gttcgatttg ttttgtaatt
    24241 gtaaattgtt gaatgaattg gctagcctca tcgacatcaa agtttgaggc agaagtcatg
    24301 taattagtaa tcgcctgagc tgcctcttga ttgctctcaa tgatttgtcc aaatcgtcct
    24361 tcttgggata attcctcagc ccctccaacg ttcgtagaga taaaagggag tcccagactc
    24421 aaggcctcca catacactcc aggaaaacct tcttgtttag acatagacaa aagaactttc
    24481 gtctgagata gatactgata aggatttttt tgataaccaa ggaaatgtac atagtcctca
    24541 atcccatact ctttgactcg ttttttcagt tcctcttcca tatcaccagc cccgataaaa
    24601 tagagatgat agttttttcc ctcttggtgt aataatcgta tcacttccac tacacggtca
    24661 gaacccttat tttcctcaat ccgtccgata gtacagatac tttgaggagc aatctcgata
    24721 tcgatcttct cttgagattt ttctagaata gtctgaaaat catatccatt gtagattgtc
    24781 tgtaatttag aagtataatc tggataaact tccttgatag aattgctggt cttttttgaa
    24841 atccctacaa ttgtattcgc agcatccaac tggcttctat gtgattctct tttagagcta
    24901 tccttaagaa gttcttcaat acttccatga atccaagata tcttcttgac ttctcttctt
    24961 ttagagaaca acagtggtgg attcataatg gtaaaagaaa cttcaacatc ataatcatct
    25021 tttacaagca aacgacgagc cagtcttgga aaataaattc tcattctcca caaaaaagct
    25081 cgtaaccatc tggtttggcg ataatcttga agggatttta aaatgcgtac atgctttgga
    25141 acagattcat atcccttgtc aaagtgctcc atttcaagaa tatcaatatc atacttttct
    25201 ggatccagat ttgaaacaat ggttgataga atcttctctg caccacctcc aagagaaaaa
    25261 gaccacataa aaaataagat ttttttctta gccaccatat tctcccttgt attctgtata
    25321 agacttatcc atatcagcga tgacagcatc atgatgcggt acctgcttgt ctgctggtgg
    25381 aggcgtcata taatccccaa aagcagttct gagatagaca tcatagccga ttggaatagg
    25441 catctctgtt ccttcaaatg gcaagaaaag attgtcttca aaagatgtga ttgggtactt
    25501 gtttctcatg tagccaggac ctgagcataa ttctgtaatg ccatcacaat cagccaaatc
    25561 atacttagtc atttctttct cagctttttt ccagatgcga taacagagag attttggagt
    25621 caaacccagt aaaatgcgac ttccccattt catgagagca ccatgctttt ctggaatagt
    25681 ttgcgcacaa aagagtgaat aaatcaaggc ccaacgaacc tgttttttcc gctcagctgg
    25741 atttttcgga taataatcca aaggcaaaac atccaaggcc agaccatgtg gcaaatccaa
    25801 atcctgctga taaggcttga tacaggtggt ttccttgtca cgaatggtaa taaaaagatt
    25861 acgatcaaca aaatccttgt gactctttga caagaaataa cgttcatctg cataacgagg
    25921 ccataattct gctaatttct cataatcttt acgaggcata aaaaagtcta ggtcgtcgtc
    25981 ccaaggaata aatcccttgt ttcgaagggc accaatagcg cctccgccac agagataaca
    26041 gagcaaatca tgttctttac aaaaggccac aaaatattca gccatctcca gactacgagc
    26101 ctgaattgct tttaaatcag tcatattgtt cattattctt tctatcgtat cgtttcatta
    26161 taccacaaac aaggggtgaa aatctattgc agactgtaaa aaatcaaagc ctgactgcta
    26221 tccaaatagc tatcaaactt tgatttttct gtcttatact cttcgaaaat ctcttcaaac
    26281 cacgtcagct tcaccttgcc gtaggtatag gtaactgact tcgtcagtct tatctacaac
    26341 ctcaaaactg tgtttttagc agcctgcggc tagcttccta gtttgcactt tgattttcat
    26401 tgagtattat cttatctcaa gcccatttga gcgagcttgg tttgatattt gttttgatca
    26461 accagcaagc ccaagcctcc ataaacatca taggcatcta cccagtcacc cagttctgga
    26521 atcgtcaatt tttcaatacc attttttgct ccatccaaaa cagataaacc gtttgttagg
    26581 aggaaagtat agggtacgtt ggttgaggtc atagcaaaaa cctttccaag agcttcagaa
    26641 ccagtgaaaa gtttagtggg atctttaatt tgctctaaaa ttgctgttaa aacttgttgc
    26701 tgtctttttg tacggccgta atccgcctca tcatcatcac ggaaacgagc ataattgagc
    26761 agggtcgagc cattcatctg ctgttttccg actttaatgg tttgggttgg agactcagtc
    26821 tcggtagcgt ataaatcatc tccgactgta gcttctgtta ggggacgccc attcaatgtt
    26881 gaaaattgag catcaatcgt caccccatca gggaaaagcg tgtcaatcgc tgtggcaaag
    26941 gcctggaaat caaccaaggc gtagtactta atgtccaagt caaaattatc tttcaagact
    27001 tggcgaacca tttctgcccc tttttgcccc tcttgttctc ctaactcgta ggctacgttt
    27061 aacttgttat ctgtctgttt tctaccgtta atcacttgac tataaccatc tatatagacc
    27121 aaattatcac gcatgaaact gactagcttc attttcttat ctgagccccc gacatttaat
    27181 accataatag agtcagttcg tgtctcaaca ctgttctggc cgattcgacc atcagtaccc
    27241 atgattaaaa tattaactcc atctctagtg tcctgaccat taaagacttc tacttgagct
    27301 gcccgggcat cagcagtttt ctttgcgcta gcatcttggt aaccacgcaa aaacatgaat
    27361 accatggcca aagccacaca gaccaaaagt gaaaaaatca ccataaaaat tcgtttaaga
    27421 cggagcttcc gtcttttctt ttttggaggg gaagagagtg cttgtgattt ggattgtgag
    27481 cgactccggt tcgcatagct tggtaagtca acctgctctt ctctttcttg ttccaagcta
    27541 gagctactat ttcccctagc aagagttagc ttttcttgca aataggcaaa ctcatttttt
    27601 tctctctcat tgagatagtg aatatttttt agcaaataat cataacgcaa ctgctcatga
    27661 tgacttaagg gattttcttt actcatcttc tctcctttcc atggtctgat attggataaa
    27721 taggataggc acccagaatt ttatactgga ttccaatcgc ttctaattct ttttgggcaa
    27781 agtggaccaa gtccttatcg gtataatcca catcgataat gaaaaagtat tcacccagtg
    27841 ctgtcttgag tggacgactt tcaatttttg tcaagtcaat tcctcgccaa gcaaaggtcg
    27901 acagggcctt ataaagtgca cctggaaggt tgtcaggtaa tgtcaaggcc aaactcatct
    27961 tttcagtttg tgcttgcaag ggaatactag gcttttcagc tcctagaacc cagaaacgtg
    28021 tgaaattggc ttccatttcc tgaatatcct cggcaatcag ttccaatcca tattcttcag
    28081 cagaacttct aggtgcaact gctgcaaagg gctgatctgg atgttcggaa ataaaacggg
    28141 ccgcataagc tgtactagct gttacctcga tttgagcctc tggatattgt tcatcgatga
    28201 atttctttcc ttgagccaag gcctgtggat gtgaaaaaat cttttcaatc ttagtatggc
    28261 ctggaaccac catcaactgc tgatgaatag gctgaacgat ttctgctact gcttggatgt
    28321 gagcctgatg aaaaagatag tccaaggttt catgaatact accctcaata gaattttcaa
    28381 ctggcaccac agaatagtcc actaatcctt gctcataagc cttgatgaca tctgtaatgt
    28441 tggcaaaagc ctgcaattcc tcatgaggaa aagctgtctg cacaacgtgg tgtgaaaatg
    28501 atcccttggg acctagataa gcaattttca tcttagttcc tctataattt cctctgggct
    28561 tagcttggtc acatccaaaa cccgactagc cacttcctca taccaagcct gtctttcttg
    28621 aaaaatagct actagttctt ccttgctatt atttagaaaa agcggtcgct gattgtcctt
    28681 atcagctgcg atacgttggt agagggtttc aaaatctgct ttcaggtaga tgttatctgt
    28741 attagtcttg agtaaatcac gatttctctg agaaataacc actcctcctc cagttgacac
    28801 gacttggtct gtttgtagta aatcagctag gacttctgat tctacctgac gaaaggctga
    28861 ttctcccttt tcagcgaaaa aattcgcaat ggacatacct aggcgcttct caatcagagc
    28921 atccatatca aggtaattag ggtccaagcc tcttgcaata gtcgattttc cagcccccat
    28981 aaaccctaat aacaccttag ccatgaatca agctctccaa atcatcaaag aaactaggat
    29041 agctggtatt gatggcttct gcacggtcaa gctccacctc tccatctgca accaataggg
    29101 ctgcgatagc tgtcatcatg ccgatacggt ggtcaccaaa cgtattgact ctagcaccgt
    29161 gaagagctga ttttcctttg ataatcatcc catctgccgt aggagtaata tctgctccca
    29221 tactatttaa ggcgtctgcc acaacctgaa tacggtctgt ttccttgacc ttgagctcct
    29281 cagcatcctt gataactgtt acaccttggg cttgggtcgc aagtagggca ataataggca
    29341 attcatcaat caaacgtgga atcaaagcgc cacaaatctc tgttcctttc aagtcagaag
    29401 actcaacaat caaggttgca gatttagcga ctggatcgat ttcagttatt tccaattttc
    29461 cacccatggc acgaatgaca tcaataatac cggtgcgagt ttcgttgatc cccacattct
    29521 gcagcactag acgagaattt ggagcaatca aacctgcgac taaccaaaag gctgcactgg
    29581 aaatatctcc tggtacgacc accttctgtc ctgtcaattt ttgtggccct tggactgtga
    29641 ttttcttacc atccacactt aaatgaccac caaattgttt caacatatct tcagtatgat
    29701 tacgggtgta ctctttttcg ataataactg actccccctt agcttgtaag gctgcaaaca
    29761 tcaaggctga cttgacttgg gcagaggcaa ttggcaactc ataatgaata ggtcttaggt
    29821 ttttcgtccc ttttaagcga aggggaggca agtctcgttc agtttgccct gagatgctga
    29881 cgcccatttt tttcagtgga agggtcacac ggtccatagg acgtttggaa agactatcat
    29941 ctccaaacat ctctacttcg aaatctgcac cagcaaggac acctgaaatc aggcgaatcg
    30001 aggtgccaga atttcccata ttaagggcat tttgcggcgc ttttaagcca gccatgccta
    30061 caccttgaat ggtaataacc ccatctttat cctcaatttc aacaccaagg tcacgaaaaa
    30121 cctgcatggt cgaaagaacg tcttcacctc gcagaatatc ataaaccttg gtctcaccct
    30181 cagccaaact tccaaagata atggaacggt ggctgataga cttgtcacct gggacgcgga
    30241 tactaccatg taaatggcga atgtttgttt ttagtttcat actggacctc atacttgcaa
    30301 tacttttacc tattttatca taaaaagcca gaaattcctt aaaaattcct gactttagga
    30361 tcgttctttt cttatttcag caattctgaa actggttcga aaacaatttt ttcaatgtca
    30421 gaaaggtaaa tggccaattg ttgttgcttg gtaaagaatt ctgacaagag gctatttcct
    30481 tgaatctgtt taccaaagcc ttccatctta gcttggaagg acgcatctgg catttgacct
    30541 gtctgtgcta gtttttgaat ttcctcttga aaggcaagat attctgtaaa gattttgctt
    30601 gcctcagcat ctgctgcaat cgcatcttta gctgctttaa cagccttgta ttctggtaat
    30661 ccgcgtagac cgcgactgag ttcgtttgca ctatcgtaaa tatttgacat gttcttctcc
    30721 ttatttgatg acgactgtat agtcggtatt ttctgttatg agatactcag ctctttccaa
    30781 gtcttgagca tttttaaatg aaatttgtag gattccgtga atatcctcac gattttcctc
    30841 gttgatgtgg atgttaacca aggaagttcc acgtagcagt tccaaaatcc gcaggatgac
    30901 atcttcttca tcaggaacgt caacatagag gtcgtaagag ctatccacac caccacgctt
    30961 atggatttcc atggtctggc gttgttcacg cgcttggtta aaaaagttcc aaatttgctc
    31021 ttcatctccc ttactaatgg cctgaccaat cgcttccaaa cgttccttga aatcctcaat
    31081 tctatccaga atggtctcgc tattggacaa gagaatggag gtccacattc ctggctcgct
    31141 ttccgcaatt cgggtcatat ctcgaaaacc acctgccgca aagcgccttg ccatctcatg
    31201 ctcttgagca tagaccgcag tctgctccat gagactagaa gccaaaatat gaggaaaatg
    31261 gctaatctga gaagtgacac gatcatgctc cttggcatca atctcgataa aacgagcatg
    31321 aagacctgaa agcagatcct tcatttcctt aagcgtgtcc tgacttgtca ggcttgaagg
    31381 tgtaaagata taataggcat tttcaaaaag attgacatct gccgaagcag cccctgtctt
    31441 gtgactacca gccatgggat gggccccgac aaagcgaaca gacttgccag ccaaatactg
    31501 ctccgccgca tccacaatgg ttgacttggt cgaaccagca tctgaaataa taacgccttc
    31561 tcgcaaatcc aaattggcca actccttaat gaaagcaata gtttgtttga ttggcaagct
    31621 gaggataatg acatctgcca aaggagcaaa actagcaaaa tcatccgttg cacggtcaat
    31681 catgccttct ttcaaggcga tatctctcga agcttgacta cgattataac ctaaaatttc
    31741 ataatctgga tgatcgcgtt tgataccaag tgccatagag gctccaatca acccaagacc
    31801 tgcgatatag attgtttttg ccataggaac tccttaatag ttctttgtat agtctcggtg
    31861 tttggctacc gcttctttta gttcctcaag attatctgat gagaattttt cgaggatttc
    31921 ttgcgccaga accgttgcta caactgcttc catgaccatt cctgcagctg gaagagcagt
    31981 cggatcactt ctctccacgg ttgccttgta aggtttgtgg gtttcgatat ccacactcat
    32041 aagaggttta taaagagtag gaatgggttt catgacccca cgaacaacga tgggttgccc
    32101 attagtcata ccaccttcaa aaccacctag attattggta cggcgagtat aaccgtcttc
    32161 tttagaccag agaatttcat ccataacttg gctgccttta cgataaccag cctcaaagcc
    32221 aagaccaaat tccacccctt taaaggcatt gatagagaca acagcttgag ccaatcttgc
    32281 atccaatttt ctatcccatt ggacatagga accaagacca actggaacgc ctccgacgac
    32341 tgtctccaca accccaccga tggtatcacc atcacgtttg atttggtcaa tatagtcctt
    32401 gatttcctgt tctcgttctt ggttgacaat agaaacttca gactgggcag ctctttgctt
    32461 aatttcagcg actgtcagat tttcaggaac atcgatttcc ttgccaccaa agaccacgac
    32521 atggttggca atctccatat ccagctcagc caagaggcgt ttggctactg caccaactgc
    32581 cacccgcatg gtggtttcac gagctgatga acgctccaaa gaatttcgca aatcatcaaa
    32641 acggtactta atccccccaa ccaaatcggc atgacctggg cgaggatgag taattttccg
    32701 cttgctttta aggcggtctt caatgtcctc cgcagacatg atgtccagcc atttctggtg
    32761 gtccttattg atgacatcca tagtaatagg cgcccctgtc gtcttcccgt ggcgaacgcc
    32821 cgaagtaaag acaacctggt cactctcaat cttcatacga ccaccacgac cgtagccacc
    32881 ctgacggcgt ctaaggtcct cattgatatc ctcagctgtc aatggaagtc cagctggaat
    32941 tccctcaata atagctgtta gacgggggcc gtgtgattct cctgcagtta aatatctcat
    33001 acactctcct tattttacca agtagtcttt catctcttcc agagaaactg ggtgaatggt
    33061 cgccgaacca agctctggca ccaagaccaa tttcaaggtg ttaccacgcg ctttcttgtc
    33121 atgagtaaga gcctgataaa acttgtcaac ttcccaattt tcatagtcaa caggcaagcc
    33181 gaatttctga cacatctctg tgatagattg ggtaatgcca gctggcatga ggcctttttc
    33241 ctcagcaacc ttggaaatct gtaccattcc catggcaaca gcctctccat gcatgacctt
    33301 gccataaccg gcagtcgctt cgatggcatg gccaatagtg tggccaaaat tgaggtaaag
    33361 acgaatacca ttgtccaact catcttcaac caccatcttg cgcttcacct gacaagaatg
    33421 ttcaatcaag gtctctgcat gttccaaaat gctctcaaca gaaccattca gtcccgtcaa
    33481 gagagcccac agttctggat cctcaatcaa gccatacttg ataacttcac ccatcccttc
    33541 aatcaactct ctttttccga gggtttcaag aacaagtgga tcaatcagaa ccccatctgg
    33601 ttgggcaaag gtccccacca tatttttagc aaatggtgtg ttaacgcctg tctttccacc
    33661 gatagaagaa tcaacctgag ctgtcaaact agtcggaatc tgaacaaagt gaataccccg
    33721 catataggta gaggctacaa atccagccag gtccccaaca acgccaccac caagagcaac
    33781 gattccatcg ctacgagtca gaccttgctt gactagaaat tcatagactt tctgaacagt
    33841 agttaaattc tttctttctt caccttctaa gaaatcaaaa acagctacct gaaaaccagc
    33901 atcttctagg ctgagcttga ccttctctgc atagagagag gctacatggt tatctgtcac
    33961 aatgactacc ttttgcggtt gccagagttc tcgcaaccac tgaccagcct gggccataca
    34021 acctttttca atctgaatat cataaggatg atgaggaata tcgattctga ttttcatagg
    34081 agagtctccc tttctttatt ggtatttttc tgttaaagac tgccaaatct cttctgtcgg
    34141 catttccttg cctgtccaca gttgaaaagc ttctgcagct tgatagagta acattcccag
    34201 accattgact gctggattgc cctgacttct agcccatttc aaaaacggtg tttcaaaggg
    34261 ttggtatatg atatctgcaa ctaagagagt ttctggtaag actatgtttt caggaacagg
    34321 agaggattgg ccatccatgc ccacactggt ggcattaact agcaaatccg actcggcaat
    34381 ccttgcttgc agttcagaaa catattctaa agcacacaaa tccactttaa agcctgtctg
    34441 ctcctgtaac ttgtctaggt aaggtcttgt tttttccata gaaacggaac gaacaaagac
    34501 cgaaatctga ctgacgccat ccaaaatagc ctgtgccaag attgatttag ccgcaccacc
    34561 tgcacccagc agggtcatct ttttacctga aattgtaaaa gaaggcaagc acttaaaaaa
    34621 tcccttgcca tctgtattat atccaattaa attgccattc tcattgacaa ccgtattaac
    34681 cgcaccaatc aagcgcgctt catcgctcag ctcatccaaa taaggaatca cctgctcctt
    34741 atagggcatg gacagattga tgccaaacat ctggtagcga cgaatattgg ccactgtttc
    34801 tgccaagtca ctcgcttcaa tctcccaagc cacataagca ccgttggtag ctgtcgcctc
    34861 aaaggctcta ttgtggatga agggagaaat agaatgctta ataggattgg caacaactgc
    34921 agttaaacgt gtatagccat caagcttcat ccaaaatctc cctgattttt ttcatgctag
    34981 ctagagaaat ctgcccaggg gcactagcct catccagact ggcaaaagac caactcgaac
    35041 cagtcacatc cgcagtgata cgagagacct tgcccacctt acccatagaa atggtcacat
    35101 attcctgttc aggattgagg gttttaaagc ctcgtgtata gttcatcaag tctaagacat
    35161 cctgctccgt gtgagccatc accgcaacct taacaagttt tggatttagg atcgtcaact
    35221 ctgacaagat ttccatcatg ttctcaggtg tttcttggaa attatggtaa ctcaaaacaa
    35281 gatttgggaa gtccagcatt tcctcaaaaa catccttgta gctatagtac tcaaaatcaa
    35341 tatagtctgg ttgatagagt tgcgcaactt ccttgattag atggatatac tcttctggag
    35401 aaaggtcgat ttctccacct tcggagcgag ttcgtagcgt gaaaaccaac tcacggcctg
    35461 cgaatttttc aaaaatggct ggagctacct gcaaaatcgc ttctttaggc agatagtcgg
    35521 cacgccattc aatgatgtcg gcatccaggt acctcgtggc atccagagcc tgagcctcct
    35581 ctaaacttct tggcattact gaaacgatta atttcattta ctaaccttca tactaatcac
    35641 cttgaggtaa ttactacttt catctttttt attataggca aaatctgctg gaagaccata
    35701 tttgtttaaa atctggtaac ttcttcctgc aaagccttta tcaatttgtt ctgtaaattt
    35761 ctggcgggaa acattggcag cattggtact ggcaatgata atccctcccg gatttaaaat
    35821 ctcaagactc tgggaaatca acttgtgata atccttggcc acagagaaag tttgtttttt
    35881 attccgagca aagctaggcg gatctaggac aatcacatcg taggtcaagt ctttgcgttt
    35941 ggcatatttg aaatactcaa agacatccat gactataaaa cgatgctcgt ctgtgctgag
    36001 cccatttgcc tgaaaatgcg cttgagacaa ttcttgtgaa cgtttggcta gatcaacaga
    36061 agttgtctgg ctagctcctc ccatggccgc agctactgaa aaagccgctg tgtaggaaaa
    36121 catattgagc aaggatttac ccatagccaa gccgtcaact aaactaccgc gaacctcatg
    36181 ctggtctagg aaaattcctg tcatcaagcc atcattcata aagacttgat acaggacacc
    36241 attttctaaa acagtgaaaa agtcaggtgc ttcttgacca taaacatggg cagattcata
    36301 gtcaaaaccc ttaaagcgga ttttctcata agcccctaaa acctcaggga aaacctgtct
    36361 aaaggcttct gatatagtct gacgaatctg ataaacataa gagttatacc aagaaaagac
    36421 ggcgtagtcg ccataaaggt ccactgtcag acccccaaag ccatctccct cttgattaaa
    36481 gagacgaaag gcagttgtca aatcatcttg atagtaggcg tttctctttt ctttggcttt
    36541 tctaaacaac gtttcaaaga aagtttgatt gaaggtcacc ttgtctttgc tgacaaacca
    36601 gcccaagccc ttgttttgct gagaaaggta ggcagtccca agaaagtttc cttcctgacc
    36661 ctgcacctct acttcctgat ccttaagatt gacattctca agatcactgg cttctagtaa
    36721 aactagcccc ttagcaagct tcttttcaac ccttttgctg actcttattc tattcataac
    36781 taccattata tcaaactttt agacaattct caaaaaagaa actacccttg cttttttact
    36841 cttcttttaa aaaatggtat actagacttc ctgcaaaact aggaagtaaa tgtgtaagaa
    36901 tcacaataaa aaatgctctt ccgtcttgga ggagcatttc tttttatcaa cgaaaatcaa
    36961 atagcaaact atgaaactag cctcaggtta actgtgagat tataggtaga gaggttgtat
    37021 cagcaatatg tgtctgtcaa atttagtgac aaaggtagta gaagaaagat gaaaaaataa
    37081 atcagcttca gtagatatct ggaaaatttg attttataga aaagcctttt gttacaaact
    37141 aaatatacta tcaataaata atattataga agcaacaata attataattt cacctatttg
    37201 catcattcta tttcgaactc taaatatatg ttctatcaaa aatacttgaa aaagacacat
    37261 tataggaatt aacgtttttg aaattgaaaa atatccaaat aaataaacta taaacaacaa
    37321 aaatagaact atgttatatt tcttattcaa aacattcctc cctatatatt tttgattacc
    37381 aatcttaatc atttacaact acattctaac aaactataaa agcgtttgtc gaattgaatt
    37441 tatcaagcaa gcgaccaacc agctcatctt ttttctattt ctgccaatat gcgtgacagg
    37501 taataatgat agccaaaaat agcaagagca agcaggagga taagagctcc tactcccaag
    37561 ttgatggcaa ggatagggga gagagactga accaagaata tgctcccaat tacaagggcc
    37621 atcaggattg cactataaat aaacaataaa actatggcga ctatgccatt tgaacgattc
    37681 accaggtccg taatgctact ccaattggtt gacagatttt taacgtcctt aaagtaatgg
    37741 tggcaagaaa ggatgacact ggcaatgatc cagactacaa gaaggtaaat catcgaaagg
    37801 atggacaagc ctagatatag agaaagaccg agcaaagtca gaactggtaa aaaggactga
    37861 acagcaaaga taatccaaaa tttcactttc acataacgag caaagtcaaa gggtaaactc
    37921 ttcagaaaat caacattttc cctctccaag gacaaggcaa ttgaatgcag gctggtgata
    37981 ttgttattga caactgctat aaacactcct acaaaaaaca agggtaacca gtatggagga
    38041 tgaatgtctg gaactatctg agaatctcgg attttggaaa tcagactgat catcatgaga
    38101 taaggaagga aagtacttgt aaaaagcact gtaatcacgc cagtcccctg tcccaagagg
    38161 gtgaggtggt agcgtaaaac catgcggaaa aatccctttt tagtagttga aatcctctcc
    38221 ttgctgcgac gttctttttt gaccttctcc tcactgttaa gcaggatcac gtcataaaaa
    38281 cgaggaagga ccttcttttt ggtcaggtaa agcaagaaaa cagttaaagc tatccaagcg
    38341 agcagaccca ctaaggcttc tgttgaaaaa ggctccactg ctattttgta aaagatatga
    38401 agaggataaa ggagaaatgg aatgtctcta actttgtcaa caatacttcc aaaagtcgac
    38461 tgtagaaaga agacaaatat taaaggtatg agaactccta tcccaatcat cacattcgaa
    38521 aaaatagact gatactttct gaagacccta gtctgagcca agaaatgcac tgccactacc
    38581 atcactagag ccacagagac aaataataag gtcaaggaca gtagcatcaa aggcaaaccc
    38641 agccatagag aaggagctag cctaatgtag aggactagaa aataagctag gattggtaca
    38701 attccagtta gagctggcaa gaggacagac agtcctttag caattataat ctctgattct
    38761 ttaaaggcat agggcctata cgataccaaa tccttactct cataaaagac attgtaaaag
    38821 gccgttaaag aagttgaaaa ggcaatcact agtaaaatag caaccatcga actaaaataa
    38881 ataggcattt cctcaaaagg aaaatgaatg gctatattac taaaacagat gagcatcaag
    38941 agactggaaa aaatgtaaga acttaggact ctagcggaaa catttacttt tttcccagga
    39001 ttcttagcct gcttctttcg tagattaacc agattagctt cttgagatga ataaaggata
    39061 ttgatatcaa ctaatttttt aatgaccttg agacgcatcc gcaacctcct cttttctacc
    39121 agcaagacta aggtagatac tttccaaaga ctgggctggg taatcttttc tcaagtcctc
    39181 tacactacca caataaatca aatgcccctt tttcaaaatg gcaatccgat cacagacttg
    39241 ctctgccacc tctaggacat gagttgaaaa caagactgtc ttcccttttt gtgcatgttc
    39301 cttcatcatc tgtttcaaat caaaggcagc ctggggatcc aaaccagtca agggttcatc
    39361 caagacccaa atatcgggat cagacaagag tgctccgatg acaaagactt tctgacgcat
    39421 tccgtgagaa agagtttcaa taacctgata gcgattttca gcaaaatcaa aaacgttcaa
    39481 tagcctagct agactagtct ccaagtcaga gctagtcaga tcataggatg aagcgatcaa
    39541 ttcccaaaat tcattggccg ttaagcgtaa aaataagtca ggcgagtctg ctacgtagcc
    39601 aatctttcgt ttgatcgcca agcgattttc cgataactcc tgaccgtcta ccaaaatacg
    39661 accactgctg ggtgaaatga tactgactag ggattttatg gtggtcgatt ttccagcccc
    39721 attatgacca atcaagccca taatctctcc attttcaatc tgcaaattga gattactcaa
    39781 ggcctcttta tcaccataca acttactaac attttgaaat tcaatcatgg gacaactcct
    39841 atctttatct gtattataca tctctatact agcactttga tacaaaaaaa tcaatacttt
    39901 attttaagta gttaaaatag tttccttcta tcttacgcaa acgtttgcgc cgagagatac
    39961 tttatgatag aataaagaac aagattgaca agtaagagga aacatcatgc aaaatcaaac
    40021 actcatgcaa tactttgaat ggtatctgcc ccacgacggt caacactgga cgcgtctggc
    40081 tgaaaatgct ccacacctag ctcatctggg gatcagtcac gtctggatgc caccagcctt
    40141 caaggcaacc aacgaaaaag atgtcggcta tggggtctat gacttatttg acttaggaga
    40201 gttcaaccaa aaagggactg tccgcaccaa gtatggtttc aaagaagact atcttcaagc
    40261 cattcaagcc cttaaagaac agggaattca acctatggcc gatgtagttc tcaaccacaa
    40321 ggctgctgcc gataacaggg aagcctttca ggttatcgaa gttgatcctg tagaccgtac
    40381 agttgaactt ggagaaccct tcaccatcaa tggctggact agttttacct tcgatggtcg
    40441 ccaagatacc tataatggct tccactggca ttggtaccac ttcaccggta cagactacga
    40501 tgccaaacgc agtaaatctg ggatttatct gatccaaggg gacaacaagg gctgggctaa
    40561 cgaggaattg gtcgataacg aaaacggaaa ctacgactac ctcatgtatg ccgacctaga
    40621 ctttaaacat cctgaagtca tccaaaacat ctatgactgg gctgattggt tcatggaaac
    40681 gactggtgta gctggtttcc gtttggatgc cgttaagcat attgactctt tctttatgcg
    40741 caacttcatc cgcgatatga aggaaaaata cggtgacgat ttctatgttt ttggtgaatt
    40801 ttggaaccca gacaaggaag ccaatctgga ctatctcgaa aaaacggaag aacactttga
    40861 ccttgtcgat gttcgtctcc accagaatct ctttgaagcc agtcaagctg gcgcaaacta
    40921 tgaccttcgt ggcattttca cagatagcct ggttgaactc aagcctgaca aggctgtgac
    40981 ttttgtcgac aaccacgata cccaacgagg acaagccctt gagtctaccg ttgaagaatg
    41041 gttcaagcca gcagcctatg ccctcatttt gttacgccaa gacggccttc catgtgtctt
    41101 ttacggagac tactatggga tttcaggcca gtatgctcaa gaagatttca aagaaatcct
    41161 tgaccgcctc ctagccatcc gaaaagactt ggcctatgga gaacaaaatg actactttga
    41221 ccatgctaac tgtatcggtt gggtacgttc aggtgctgaa aatcaatccc caatcgcagt
    41281 ccttatctca aatgaccaag aaaacagcaa gtcaatgttt gtcggtcaag aatggactaa
    41341 tcaaaccttt gtagatttac ttggtaacca ccaaggtcaa gttacaattg atgaggaagg
    41401 ttatggacaa ttccctgtct cagctagatc cgtaagtgtc tgggcagtca ataccatcta
    41461 atagctcata ataaccaagc taggtccaag cggatttggc ttttttgtat tcacaaaaag
    41521 acctacccaa atggatagat ctttacttga ttacaattta cctgctactg catccaacaa
    41581 ttcttggatc ttagcttggt tgcttcctcc tgccatggcc atgtctggtt taccaccacc
    41641 acgtccatcg atgattggtg ctaattcttt gacaaggttt cctgcatgaa ggtcttttgt
    41701 cttgcttgct acaaggacat tgactttgtc accgatagcg gcaactagga caagaagatc
    41761 agagtagtct ttttgtttcc agttatctgc aaaagtacga agggcaccgg catcggatac
    41821 agacacttga ctagcaatgt aacgatgacc gttgacttcc ttagcatctt tgaagatatc
    41881 gcctgcggct gcagctgcgg ctttttcttt caactcagca ttttcttttt gaagttgacg
    41941 aagttgttct tgaagtcctt ctaccttgtg aggtacttcc ttgacttgag gtgctttcaa
    42001 gattgctgcg acagctttaa gagcatcctc ttgttcacga taggcttcaa aggcttcctt
    42061 accagtcact gccaagatac ggcgagttcc tgaaccgatt ccttcttctt tgacaatttt
    42121 gaagagacca atctcagaag tgttgccaac atgagtacca ccacaaagtt caatagagta
    42181 gtcaccgata gtcacgacac gaacttcctt gccgtatttc tcaccaaaga gggccatagc
    42241 tcccatttct ttagcagtgt caatatccgt ttcaactgtc ttaacttcaa gagcttccca
    42301 gattttttcg ttgacttgct gttcaatcgc acgcaattct tcagcagtta cagcttggaa
    42361 gtgggtaaag tcaaagcgaa ggaattcaac ttcgttaaga gatcctgcct gtgttgcgtg
    42421 gtttccaagg atattgtgaa gggcagcgtg aagcaaatga gtcgcagtgt ggtttttcat
    42481 gacacggtga cggcgattgc tatcaattgc caaggtatat tcttggttca aggcaagcgg
    42541 tgcaaggact tcaactgtat gaagggcttg accatttggg gctttctgaa cattggtcac
    42601 agtagccaca accttacctg actcatccaa gatttgtccg tagtcagcta cctgtccacc
    42661 catttcagca taaaatgacg tttccgcaaa gataagagag gcagttcctt ctgaaacagc
    42721 ttctacttct gcattgtccg ccacgatagc taccaattta gaagacaatt ggctagcatt
    42781 gtagttgaag acactttcta cagtgatgtt ttgaagagtt tcattttgca tacccattga
    42841 gccacccttg acagctgagg cacgcgcgcg ttcttgctgt tctttcatgg ctgcttcaaa
    42901 accttcacgg tctacagtca taccagcttc ttcagcgatt tcttcagtca attcaactgg
    42961 gaacccataa gtatcataga gtttgaagac atctgaacca gcgataacag attgaccttt
    43021 ttctttcaag tctgctacaa tgccttgggc aaagtgttga cctgagtgaa gggtacgggc
    43081 aaatgattct tcttcgctct taacgatttt ctcaataaag tcacgtttct caagcacttc
    43141 tgggtagtag ctttccatga tttttccaac agttggaacc aatttgtaaa ggaaaggttc
    43201 gttgataccc aatttttgac catgcataga agcacgacgg agaagacgac gaagaacata
    43261 accacgacct tcatttcctg gaagggcacc atcaccgata gcaaatgaaa gagaacgaat
    43321 gtggtctgcg ataaccttga agctcatgtt gtcgccatct tggtcataaa ccttaccaga
    43381 caatttctcg acttcacgga taatcggcat gaagaggtcc gtttcaaagt tggtcttagc
    43441 cccttggata acagccacca aacgctccaa accagcgccc gtatcaatgt tcttatgtgg
    43501 caattccttg tattcgctac gaggaacagc agggtctgcg ttaaattgtg acaaaacgat
    43561 gttccagatt tcaatataac ggtcgttttc aatatcttct gcaagcaggc gaagaccgat
    43621 attttctggg tcaaaggctt ccccacggtc aaagaagatt tctgtatctg gtccagaagg
    43681 tcccgcaccg atttcccaga agttgtcctc aattggaatc aagtgacttg gatccactcc
    43741 cacttcaatc cagcggttgt aagaatcttt atcgtctgga tagtaggtca tgtaaagttt
    43801 ttcagcaggg aaatcaaacc attcagggct tgtcaaaagc tcataagccc aagtgatagc
    43861 ttcgtcacgg aagtaatccc cgatagagaa gttccccagc atttcaaaca tggtatggtg
    43921 acgcgcagtc ttccctacgt tttcgatgtc gttggtacgg atagcctttt gggcattggt
    43981 aatacgtgga ttttcaggga taatggtccc gtcaaagtat ttcttaaggg ttgctacccc
    44041 agagttgatc cacaaaagag ttgggtcatt tacaggaacc aaacttactg atggttctac
    44101 tgagtgagct ttggtcgccc agaaatcaag ccacatttgg cgtacttgtg cactagatag
    44161 ttgtttcata ttgtctcctt atttacttgt ttaatgtgat tggctttcca gcatttccac
    44221 atagtcaatc gcgacacaga gggaaatgac taggtctgca taagcgtcct caagaaccgt
    44281 tacggtatag gtagaggtca gatggaagag ttccttctta atttccgcaa tcagctgatc
    44341 gcgatcatcc agcaatttga aattcaaatc ccagatattg ccctcgatac gaagacctag
    44401 attatcaaac tcatacttat ctcgccagaa ggtcaacttc ttacgaatga caaaactcga
    44461 gccatcccga agctgaatct caaaacgagg aagcaaggtc aagatttctt tactaatctc
    44521 actgacttgt tcaccagccg catcatagat ggtaaaggtt ttaggaatct taaaaaatga
    44581 tccctccacc tgataggcaa tttctcccct gtcattcttg atagcgaagc gttcgcctcc
    44641 aagacgaaac ttttgtttga caagaaatgt tttcatcaac acctccaaaa atcaaaagac
    44701 aagctcatat cacgaagggc gaaaaaccgc ggtaccacct tcattcaatg aacttgtcat
    44761 tctcttgttc ttatgcaatt gtatgattga gtagcatgac ttcctagctt agatggctcg
    44821 cagcaccgcc atttctctgg actaagacaa gtgaaaatca attctcaact ttcttattat
    44881 aacgtttttt taagcttgcg tcaactggaa atgatctccg ttgaattaga ccaattccct
    44941 acatctctga ttactttttc aggatatatt ttttcttact gccgtttttc tttttatccc
    45001 aaattttcat attactaaac acagctacta gaatatttcc aaatataaag gtgcctatca
    45061 cccaatatat ggactcagtt gttaggtatt gtcgatccaa gccatccttt aaatggaata
    45121 gtataacagt ttggttaaca atcataaagg ttggccagaa actttttttg aaaaaagtag
    45181 acattttcat tatttgttgc cgctttctgt aaggttaata ctcaataaaa atcaaaaagc
    45241 aaactaggaa gctagcctca agctgtactt gagtacggca aggcaacgct gacgtggttt
    45301 gaagagtata ggcttagtat actactaggc aagcaaataa gcaaataaac aaataaacaa
    45361 ctagaataga aaaagatagg gctctaaaaa ctgacttcta ttccttaaaa acgaaccagc
    45421 ttgactgatt cgtcttctta cgtttatctc ctacttccga tacattttaa actgtaggaa
    45481 gaggtcgcta tatttccctg tccatttatg gtcaaatttc tcataaactt ctaggtgttt
    45541 catggtttca acatcgggat agaaggcctt atcttccttt gtttcctctg ggagcaattc
    45601 cttcgctggt aggtttggtg ttgaatagcc gacatactcc gcattttgga gagcattttc
    45661 aggtttcaac ataaagttga taaaggcata ggctgagttt tggtttttaa ctgttttggg
    45721 aatgaccata ttgtcaaacc aaagattgct ggcctctgtc ggtaccacat aacgtagatt
    45781 ttcatttttt tctaacattt ggctggcttc accagagaag gtcacgccga ttgcaacatt
    45841 attctgaatc atatagccct tcatctcgtc cgcaacgata gccttgatat ttggagtcag
    45901 tttgtagagc ttatccactg tctcttccaa ctgctgcaga tccttggagt tgaggctgta
    45961 gccgagggaa ttgagtccta gtcccagcac ctcacgcgcc ccatcaaaga gcatgataga
    46021 attcttatac tccggcttcc aaaggtcatc ccaatgctca ggcgcttcat ctaccatggt
    46081 ttcgttgtag acaattccta aggttcccca gaagtaaggg atggagaatt tattacctgg
    46141 gtcaaaggac tggttgagaa actctggtcc gatattttcg attcctttaa tttttgaata
    46201 atcaagcgga accaagaggt cttcgtcctt catcttgtta atcatgtatt cacttggaat
    46261 ggcaatatcg taggtcgttc caccctgctt tatcttagtg tacatggctt cgttggagtc
    46321 aaaagtctcg tactgaactt gaattcctgt ttcttctgta aactgagtca agagttcagg
    46381 atcgatatag tctccccagt tatagataac caatttttga ctatctcgac tattgatttt
    46441 actatctaaa tgagtcgcaa ttccccacaa gacaaggata atcgctgcaa ttcctgctaa
    46501 aaatgaatag atttttttca tgcttgctcc tccttctcac gagagataaa gtaataacct
    46561 acaactagga taatactaaa gagaaagact agagcagaca gggcattgat ttctaaggaa
    46621 atccccttgc gagcacgaga gtaaatctcg actgataggg ttgaaaagcc atttcctgtt
    46681 acaaagaagg tcacggcaaa atcatccagc gaataggtga aggccatgaa gtaacctgca
    46741 atgatagacg gagtcaggta aggaagcatg atttccttaa acatctgaaa ttgactagct
    46801 cccaagtcat aggccgcatg aatcatgtcg ccattcattt ccttgagtcg aggcaagacc
    46861 atcaagacca cgataggaat ggagaaggcc acgtgactag atagaacggt caaaaagcca
    46921 agtgaaaact tgagttgggt aaagagaatc aagaagctag caccaatcat aacgtcaggc
    46981 gcaaccatga ggatattatt gagtgataga aaggcttctt ggtatttctt acgagactgg
    47041 tagatgtaaa tggcaccaaa agtcccgata atggtcgcta tcaaggctga taggaaggcc
    47101 aagaaaaatg tctgagccaa aatcagcatg agtctcccat ctccaaacat ggtttcaaag
    47161 tgagtccagc taaaacctgt aaagctattc atatcatcac cagcattaaa ggcatagcca
    47221 atcaagtaaa aaatcggcag gtagaggacc agaaagacca gtcccagata aaggttggca
    47281 aattttttca tcgttctctc ctttccttgg tcacccacat ggtgatgaac atggtcagga
    47341 tgagaatcac accgatggtt gaacccatac catagttgtc attggttaga aaattctgct
    47401 caatagccgt ccccaaggtg ataacgcggt tcccaccaat caaacgggtc agcatgaaga
    47461 gactcaaact tgggataaag accgactgaa ccccacttcg cacaccgttc atagatagag
    47521 ggaagatgac atgacggaag gtctcccact tagttgcacc aaggtcgtaa ctagcattga
    47581 tgagattatt atccatatcg tctaagacat tgaaaatcgg caaaatcata aaggggagct
    47641 cgatgtagct tgcgacaaag ataaaggaaa aatcggtaaa aagcaactgt tgtgaaccaa
    47701 ttccgataaa ttccaagaat tggttaatag agccattttg accaaaaatc ccgataaaag
    47761 cataggcttt aaggagcaaa ttgatccagg taggaaggat aatcagcatg agccagagtt
    47821 gacggtgctt gagacgggtc aaaaagaggg ctgttggata gctgataagc aaggtcacaa
    47881 aggtcacaat ccctgcataa agcactgagt tgaaactcat tttgaggtag gtcaagtttt
    47941 gtgacgcaaa gtaagattta taattttcta aactaaactg gccttcaatg ttgaaaaagg
    48001 attgtccgaa aatcaagacc aagggtgcca atacaaagag ggcaatccaa agcatgtagg
    48061 gcactacaaa gagtttagag cttgttttct tcatctcttt cctcctcgat cgcattgatc
    48121 agacctgctt cttgctcttc gatttccacg tattcttcga tacgagcatc gaactcttct
    48181 tcggtttcat tgagacgcat gatgtggatg tcttctgatt caaagtccag accgatttcc
    48241 tcacccacga tggccttacg ggttgagtgg atcatccatt catttccaag ttcgtcatag
    48301 gcgataattt cataatgaac tccacggaag agctgggtgt cgaccttaac ttggagtttg
    48361 ccttcttcag gaagggtaat gcgcaagtcc tctggacgaa taacgacctc aacaggttca
    48421 tttggcttca tcccaccatc aaccgcttca aagcgtttgc cgttaaattc gaccaagtag
    48481 tcctcaatca tggtacctgg caagatgttt gactccccga taaaggtggc aacaaagtgg
    48541 ttgattggct catcgtagat gtccacaggg gttccagact ggacaatctc gccatcattc
    48601 ataacgaaaa tccagtcact catggcaaga gcttcttcct gatcgtgagt gacaaagaca
    48661 aaggtaatgc ccaatcgttg ttgtaattca cgcaattcgt actgcatgtc tgttctcaat
    48721 ttcaagtcca gcgctgataa aggctcgtcc aacaagacca cacggggttg gttgatgata
    48781 gcacgggcga tggccacacg ctgacgttgt cctccagaaa gtttgcggat ggaacgtttt
    48841 tcataacctt ccaactgaac catcttgaga acttccgcta cacgctgctc gatttctttc
    48901 ttatcaattt tacgcaagcg aagtggaaag gcaacatttt caaacacatt catatgtggg
    48961 aacaaggcat aggattggaa gacggtatgt acgtcgcgct tgttggttgg aatatcattg
    49021 atacgaacac cgtctagcat gatatctcct gtcgtcgcat ccagtaaacc tgcaataatg
    49081 tttaggatag ttgatttccc cgaaccagat gcacctagaa gggtgtagaa tttcccttct
    49141 tccaactcaa agttgatgtc tttgagaacc ttggtgttgc tgtcttcaaa aactttagag
    49201 acgtttttga attcgataat tggttttttc aattggcata aattccttct ttttcataga
    49261 ttaaccgatc ggggctctgt caggtcccca ctacctcttg cagggagtaa aaccacctgc
    49321 atacatcttc gctaccgata ggctttcacc ccctttccat gacatagcag cagcttttca
    49381 aatacagctt cctacttgct ttcacccaag atccggactt ctctttcaag cgtaatacct
    49441 gagtgttcct tgactttttc gataaccgat tggatcaagt cctcgtagtc tttggccgtt
    49501 ccatctgcga cattgatcat aaatcctgca tgcttttctg acacttctac gccaccgata
    49561 cgatagcctt tcaagccagc ttctgaaatt aactgacctg caaaatgccc gactggacgc
    49621 ttaaagaccg agccacaaga tgggtattcc aaaggttgct tgagttcacg taggtgcgtc
    49681 aagcggtcca tttcctgctt gataacctga tgggttcctg gggctagggc aaatttaact
    49741 gacaagacaa ctgcaccaga ctcctgaata gctgaatggc ggtaaccaaa agccaagtct
    49801 ttagcagaca gggtttcgat ttctccatcc ttggtcaaga ccttacaaga ctgcaagatg
    49861 tgagcaatct cgccaccata ggcacccgca ttcataaaga cagcaccgcc aacgcttcct
    49921 ggaataccac aagcaaactc aaagccagtc aaactatgac ggagggcaat gcgagttgtt
    49981 tcaatcaagt tagccccagc ttctgcttca atggtatagc catcaacaga aacgttattg
    50041 agcttgtcac acaagatgac aaatccacga atcccaccat cacgaacgat gatattgctt
    50101 gcattgccaa gaaccatcca agggatattt tcttggttgg caaatttcac aaggcgcgcc
    50161 aactcaaaac gatttcgtgg aaagaccaaa taatcagcct ctccacctac ttttgtataa
    50221 ctatagctat gcaagggttc cttaaaacgg atatcaattc cttctaagat ttcaagcatt
    50281 ttttctctta cagacatgtc actcttcctt ttacaaaatt cattccatta taccattttt
    50341 agagacattt gacgaccata aaaatacctt gtttggattt tgcataagaa aaagaggttc
    50401 cccccttttt atgatttttt acaaaagatt tccttggttc cataggcgac cagaacgagc
    50461 tccagtgcta gaatcacttc aaccaagact ggatttgtca accagcctac ttggaaaaga
    50521 gatggtgcca gatcaaagaa ggcatgcaag ccataggctg ctaggagata aatccatttc
    50581 ttctggcgaa cagcttggta aacccaaact gtcaaaagta attggaaacc aagcgccaag
    50641 attcgctcaa aaccaagcaa ataaatctgc cagaccgaaa gtgactgaat ggtttttaac
    50701 atattttcag acagtaattg cataacctgt ggattctgag tttgaactgc cgaaagaacg
    50761 atgtaaagat tgagtaaact aataaggcct agaaaaatca actccaagcc accatgccct
    50821 aggccatagg ccaaggcatc tgccttttcc aaacttctct ttttctccaa ccatttgaag
    50881 aaaacaagac gagccgtttc ctcaaaaaat gctgccatgg ctaggccata gataatatag
    50941 ataagcggat gatcttgcaa gagggcaata ctaccgtctt tttgagggtg caaaatcaag
    51001 atatgcacca gtttttccaa aatctgcgaa gagacaaaga aagcgactgc acccaagccc
    51061 aagacagcta gattaatctg gtatttcttt ttggcaaacc aaatgcttcc tataagaaaa
    51121 gctagcaaca gcaacatggt aataatgata tgaatggtca ttttcttctc ctattctgcc
    51181 ttttcaatat cttttttcat ctcgtcaaca ttgaacttag caaacaagta ttgacggtct
    51241 tggactggga aacgttggtc caactggtca actgctccca cctcgataat gccttccttg
    51301 atgacaaaat ccatgacatg tccaccgaag gtcaaatcat ctgatatgaa gtgcagatgg
    51361 tagcctgcca cactgacccc atggaaaatc tcaggcgtcc agaaaccaac aatagtcccc
    51421 gcaacattgt cacgactata ttccggttga tgggttgcga catcagcaaa cttagtatcg
    51481 ggtgttgact taggaatcat acgcacatgc atatgtgaaa attctccccg aatcttgata
    51541 gaacggaaaa gattttcccc atcataataa gactcaattc gttctttcaa ttccttgtct
    51601 gtcatctcaa agcgctggcg gaaaatgacc tctgcctgat gcggtaccac tgcagcgtaa
    51661 ggaataaggg catctggtga cacttccaca atttctggct ggtctcctga ccctttggcc
    51721 tgataagcct tgccatccaa gacaatcaat tccccatcaa tagaatccaa ggttcccaaa
    51781 ccaaggtcac catgctctag caattctccc actgtcatgg taccaccata aaggccagcc
    51841 atcaaggctc caagagtatt gtattgaaat aatttcactg gttcctgcac gttcttatcc
    51901 attcactttc ttgtctgtta ttctataaat cttactccta agtataccac atttgcccct
    51961 agatgtgaac gagagaaacg ctctagacat tgccaagaag gaaaaaaaag ggtacaatgt
    52021 aacaaaatca agggaggtct ggaatgaaga aacaaagcaa gtacaaagag gtcgtttcct
    52081 atctgaaaaa tggtatcgag tctggacgat ttccgacggg tagtcgccta ccttctatcc
    52141 gtcaactgag ccttgacttt cactgtagca aggacaccat tcaacgagcc ctgctggaat
    52201 tacggcacga acaatacctc tatgccaagc cccagagtgg ctactatgtc ctagaacaag
    52261 ggcaacacca ggacctagaa atcgaggtta ccgacgaaca tgccagtgcc tatgacgatt
    52321 tccgactctg tgtcaatgaa accttgattg gccgagaaaa ctacctcttc aactactatg
    52381 ataatcaaga aggattagaa gacctaagac aatccattca caaactcctc tttgagcaag
    52441 ctctctactg caaggctaac caactagtac tgacttctgg aacccaacaa gccttgttta
    52501 tcctctctca aatatccttt cctagccaag ccaaggaaat cttggtggaa cagccaacct
    52561 accatcggat gaatcgcctc ttgattgcac aggggctgga ctatcaaacg attgaacgag
    52621 gcattgatgg gattgacctg aaggagctgg agcgacactt caagacagga aaaattaagt
    52681 ttttctacac cattccccga tttcactatc ctctgggaca ttcctattct gagcaagaca
    52741 aacgatccat tcttaactta gctgccaagt atgatgtcta tatcgtagaa gacgattatc
    52801 tgggtgattt ggactccaag aagggccaaa ccttccacta tcttgataca gaggagcatg
    52861 tcatttatat caagtccttc tcgaccagcc tttttcctgc ccttcgtatt acagcactca
    52921 ttcttccaaa tgctatcaaa gaagcatttg tggcctacaa aaatatccta gactacgaca
    52981 gcaacctcat tatgcaaaag gccctgtcac tctatattga cagtcaattg tttgaaaaaa
    53041 atcgtttggc tcgcttgacc aatcatgaat cttaccaaaa acaaatcgag gaaaggataa
    53101 ctaaaacacc ttgtcccctt cctcattatc ccctacacga tggtttattg ctagacctga
    53161 gacagtatcc taaaatcgcc agtctcaaac acagtcaacc gggcttggac ttctttgaag
    53221 aggcctattt aagtacctgt ccttatcaat ttgccaaggt gtccctagac aatctggaaa
    53281 atgttttaaa ctatttaaaa gcagaattgg aatgacatcc aactctgctt tttcttattc
    53341 ttcaacttca gttagacttg ctgctttttc aagatagctt tggtaaattc cttcatcctt
    53401 aagtttttgg atgaccttgt ctaccacttc tttcaaatca tcactatttt ttctaagagc
    53461 aacggcattg gcgtcgccgt ccttcatctt caagctgaca gttgcgacag ctaagccagc
    53521 gtttttagca gcataactaa gtgcaacagg ctcatccata tgaacagcat ctacttttcc
    53581 agcctgcaat tcattgactg cttcacccat attagttagg gaagttaatt gagcttttgg
    53641 caattgttcc ttgaccattg attctggaac agtccctttt tgggctgcaa tattagcact
    53701 ttctaggcta gttaaatcct tgtatttttc cacatcagcc ttacgaacca agaaactaat
    53761 cttgttttca tagtatggga ttgaaaaatc aaagacttct tttctctcgt cagtagcact
    53821 aattcctgca actgctaggt cagccttacc agtttgaaga ctggtcaaaa cattgtcaaa
    53881 actcatgctt gagatttcca acttaacccc aagttcatca gcgatagcct gagccatgtc
    53941 gatgtctgca ccgactacct ggttctttcc atcaaccaat gattgaaatt caaagggtgc
    54001 atagtcagga ctggttgcca caactaattt ccccttttgc ttaattgcct caacagctga
    54061 ctgagaacca ttagaacctg actggcaagc tactaagaag aaacttgcaa gaaaattaca
    54121 taaaacaaat atccattttt ttgatttcat aaataaacaa cctctctgtt aattttgtat
    54181 aattataacg atatccaagt tacttgtcaa gtgtttttta aatttttatc tcaaaaatat
    54241 tttttcgttc aaaaaaagga gccatcagtt gatttcaagc tcctttttat acagaattaa
    54301 actattttat agttcgacaa tcttacctgt ttcaaagtag acaacccatt cacagatatt
    54361 tttagcatag tcaccgatac gctccaagta ggaaataact tggaaataat cacgacccgt
    54421 aacaatggct tctggatttt tcttaatctc ttcagtcgca aggtcacgga tagtttcaaa
    54481 atagtggtta atttgctcat ccatggaggc cacccggtat gcgtcgtcaa cagaaccatt
    54541 aagataaaga tcaagtgctg cttcaacaac gcttttaact tcacgtccca tttttttaat
    54601 ttcttcctct acagctggaa tacgttcttc ccccttcata cggatggttg cctgggcaat
    54661 ggctacagcg tgatccccca tacgctccac atctgataca gccttaagga cagtcaagac
    54721 tgtacgcaaa tcttgagaga ctggttgttg gagtgcgatc atttcaaatg atttcttttc
    54781 cagtttcact tcgtattcat ttacttctgc atcatcttcg atgacctctt ttgccaggtc
    54841 acggtcatgc gtgacaaaag cacgtaccgt acgattgatt tgtgagagca cttcttgtcc
    54901 catagcgtag aactggttat gtaatttctc taaatcttct tcaaattgag atcgtaacat
    54961 ctttcatctc cttatccaaa ttttcctgta atatagtctt ccgtttcctt gtgttgggga
    55021 tcaaggaaca tctgcttggt atcattaaat tcaatcaaat ctccatctag gaaaaatcct
    55081 gtcttatcag agatacgtga agcttgctgc atggaacggg ttaccagaag catggtgtac
    55141 ttgtctttta gaccatacaa ggtttcctca attttaccag ctgaaatcgg atccaaagcc
    55201 gaagttggct catccaagag gatgatttta ggactagttg ccaagacacg ggccacgcag
    55261 acacgctgct gttgaccacc tgacaatcca atagctgaat catatagacg atccttgacc
    55321 tcatcccaga tagaggcacc ttgcaaggct ttttctacgg cttcatccag aacctgctta
    55381 tccttaattc cattgatacg aagcccgtag acaacattct catagatagt catagggaaa
    55441 ggattaggtt gttggaaaac cattccgatt tccttacgta attcaaccgt atctgtacgc
    55501 ggactgtaga tgttgtgacc attgtacacc acggatccag ttgtggtcac ctctggattg
    55561 agatctccca tgcggttgag agacttgagg agggttgact tccctgatcc agatggacca
    55621 atcaaggctg taatttcctt aggttggaaa gatagggaaa cactattcaa agccttcttt
    55681 ttattataat aaacggacag gtctgatacc tgtaaaatcg catctgtcat acggtttcct
    55741 ttctaaccaa agtgaccaga tacatagtca ttggtggact gtagcttggc attttggaaa
    55801 atagttgcag tcttgtcata ctcaatcaaa tcacccaagt aaaagaagcc tgtatagtca
    55861 cttgcacgag cagcctgctg catattatgc gttacaatga tgatggtaaa gtttttcttg
    55921 agctcaaaca tggtctcttc tagttgcatg gtcgcaatcg gatccaaggc tgaggctggc
    55981 tcatccatta agaggatatc tggcttaaca gagatggcac gagcgataca gagacgttgt
    56041 tgctgaccac ctgataaggt caaggctgac ttgtggagat cgtctttaac ctgatcccag
    56101 agggcagcct gacgaaggga ggtttctacg atttcatcta ggacttgctt atccttaact
    56161 ccagcacgtt catgcgcaaa ggtaatatta cggtaaattg acttagcaaa tggattgggg
    56221 cgttgaaaaa ccattccaat gtgtttacgc atttcataaa cgttgatttc tggacggttg
    56281 acatcaattc cacgatagag aatctgccca gttactttag caatatcaat ggtatcattc
    56341 atgcgattga gactgcgtaa gtaggtagat ttccccgatc ccgacggacc aatcaaagct
    56401 gtaattttat ttctttcaaa ttgcatatca atccccttaa tggattcatt tttaccatag
    56461 taaacatgga catccttagt agaaagggct actttttctt caggaaaggt aaggatatgc
    56521 ttctcatccc agttatatgt tgacatggct tctcctttag gcagcggtta atttcttgtg
    56581 tagatagatt ccgaacttac gagctccaaa gttaaaaatc aggataaaga tcaggagcac
    56641 agcggcagaa cctgctgata caatggttcc atctggaata gtgccttcac tattgacttt
    56701 ccagatatgg acagccaagg tttctgcttg acggaagata gagatggggc tagtcacact
    56761 gaggatattc cagttagacc agtcaagagc tggcgccgat tgccctgctg tatagatcag
    56821 agctgcagct tcgccaaaga tacgaccaga tgccaagacg acacccgtta caatacctgg
    56881 aagcgcttct ggaataacaa catgaaccac tgtctcccag cgagaaatcc caagagccag
    56941 accagcctca cgttgggtat ggtgaacgtg tttcaaacta tcctctacat tacgcgtcat
    57001 ctgaggcaag ttaaagactg tcaaggccaa ggcacctgaa atgattgaaa acccatactc
    57061 aaactggact acaaagatca agtaaccaaa gagacccacc accactgatg gtaaagagga
    57121 caagatttca atacaagtcc gcacaaagtt ggtaacagga ccttttttag catattcagc
    57181 caagtaaatc ccagctccca tagaaagagg tacagaaata atcaaggtaa tgaccaatag
    57241 gaaaaaggaa ttgtaaagct gaatgccaat cccaccacct gcttgaaaag cagaagacct
    57301 tccagtcaag aaagaccaag agatatgggg caagccccga accaagatat agagaattaa
    57361 ggaagccaag attgtcacaa tgatgctagc aatcgtatag aggacagctg ttgcaagttt
    57421 atctaatttc ttagcgcgca taatttttct ttcctctttc tttcgtaatc aatttaatca
    57481 cactgttaaa aactaaactc atcaagagca gtaccaaggc cagtgaccag agaacattat
    57541 tatttacagt tcccatgaca gtgttcccaa ttcccatagt taatatagaa gttaaagttg
    57601 cagctggtgt ggtcaaggaa gttgggataa cagctgagtt tccgacaacc atctggatag
    57661 ctaaagcctc accaaaggca cgcgccatcc caaagaccac tgcagtgaaa ataccagaac
    57721 gggccgcctt caagatcaca cgccagatag tctgccagcg agtggctccc atagcgaaac
    57781 tggcctcacg ataataacga ggaaccgcac gcaagctatc cgttgtcata aaggttacgg
    57841 tcggcaaaat catgacaaag aggacggaaa tccctgacaa aatcccaaaa ccagtcccac
    57901 caaagacact gcgaacaaag ggaacgacga cttgcaagcc aataaatccg tacactactg
    57961 aaggaatccc aaccaggagt tcaatagctg gttgcaaaat cttcgcccct tttggtgata
    58021 cttcggtcat aaaaactgct gcaccaatag caaagggtgt tgcgataagg gctgagagaa
    58081 tggtaacgat aaaggaaccc aaaatcatag gaagggcacc aaattcttta ctagaaggat
    58141 tccaagttcc tcccaaaaga aagtcaaaga tattcacacc attgacaaag aaggtcgaca
    58201 agcctttttg cgctacgaaa accaaaatca tggccacaag gatgactatc aaagaaagac
    58261 aggcaaaggt caaacctttt cctaatttct ccagacgaga attctttgat ggaagcaaca
    58321 ttttcttagc taattcttct tgattcatta ttgtctccct tccaacactg tcacagttcc
    58381 ggcagcatct ttttcaacct tcatttcctt aatcggaata tacttcaatc ctttgacaat
    58441 cccttcttgg gtctcatccg agagaacaaa attgagaaat tctgcagcca actcattggg
    58501 ctgccccaat gtatacatat gctcataaga ccacaagggc caattattgc tacttatatt
    58561 ttctggactt aagtcatagc cattcaactt catgcttttg accgaatcat ctatataggt
    58621 aagagataaa taagagatag ctcctggact ttttgatacg attgatttta ccgctccatt
    58681 tgaatcctgc tcctgacttt gcatggcaga ctgaccttcc ataatgacag tatcaaaggt
    58741 agcacgagaa ccagagccgg ctgcccgatt gataacagag atgggtaagt ccttaccacc
    58801 aacctctttc caattggtta cctcacctat gaagatttga cgaagttgct ctgtcgttag
    58861 gttatcaaca tcaacctcct tattgacaat cagagccaag ccagctaccg cgaccttgtg
    58921 gtcaacaaga gcagaagcat caattccgtc tttttcctca gcaaatacat ctgagtttcc
    58981 tatatcaact gccccagact gaacctggga caagcctgta ccagaacctc ccccttggac
    59041 attgaccgtt tttccaacat ggatcgtgcc aaattcatct gccgctactt caaccaaggg
    59101 ttgcaaggca gttgagccaa cagccgttat ggattctcca cgatcaatcc agctagcaca
    59161 gcctactaaa caagccgtca gccaaaaagc gataagagac agagcaagct tttttctttt
    59221 tttcactgtt tttctcctcg aaaataatta tgaatactgt gaatttttta agtagttctt
    59281 tatgagttga cgcatgaatt cttaccaaat ttctgcgcaa ttgattattt atataatata
    59341 ggctatatta ctctttccta acctcctttt ttcatatgtg gataaaatct cttgtctatc
    59401 ccttccccca ttgtcaccca ttatagtcat ttcgtgtctc tttttcccct ttttaatgca
    59461 agggaaatta ctctccttag atgataatcc aaaagctaga aaggtatctc aaacctctct
    59521 actctcccag actagtttac aactaaaagg aaaagattct attttatgag aaatctagtt
    59581 tacaagcggt aagaacgcta ataactaaac ttcttgtact ctttgaaaat ctcttcaaac
    59641 cagtgttttg agctatctat ggctagcttc ctagtttgct ctttgatttt cattgagtag
    59701 taaaactaca tgtaatggca atcaagatat caagaatcat cctactaaaa aaatccatac
    59761 tttcactata acatagaata agatatttga ctagcatttt catttgaatc tgaggccttt
    59821 tggaaaataa tttttcaaaa catttccagt aacctttgca aagcccaagc cattgccttt
    59881 aaccaaaact tggtaccaac catttggcag actttctgcc agctgaacga tttctccagc
    59941 cgcatacttg acaaacgctt cttggccaat ttcaaccgac tgttcgacct gactcggttt
    60001 caaggctaaa ccaagagcga aactgggctc aaagcgtttc ttcttaaaag tgcccagatg
    60061 cagtccattg cgagcaatct tgagcttccc taaatctggc aaaagttctg gcaagagata
    60121 aagctggtct ccaaaagtct gcaagatacc cggtagattg accttcaaat ggttttgggc
    60181 aaattcctgc cacaaggcaa cttgttcacg gctgaggtta ctcttacttg ccttaaattt
    60241 aggagctgga ttgttaccct taaactgtag atgggcaaca aactgaccct ctcccttaaa
    60301 ctgatgaggg tacatccgag ccgtttctgg caggtcaata ccagctacca ttccattgat
    60361 atgctctact ggcaacaagt caaaatcata ctcttccagc aaccaattga caatctcttc
    60421 gttttcctcg ggtgcccagg tacaggtcga ataaaccaga cgaccacctt cagctaacat
    60481 ggtcactgca tcctccagaa tttctctttg caagctagca cattgactcg gataatctaa
    60541 gctccaatag tccatagcat caggttgctt acgaaacatt ccttcaccag agcaaggggc
    60601 atcaagaacg attaagtcaa aatagccttt aaagaccttg accaagcggt cggcagattc
    60661 attggtcacc acgacatttg tcgctccaaa acgctccatg ttttcaacca aaatcttagc
    60721 ccgtttgctt gaaatttcat tggaaacaag tagcccctcc cctgctagat aggctgccag
    60781 ttgagttgat ttgccccccg gtgcagcagc caagtccaag accttcatac caggactggg
    60841 ttgagctact tgagccacca tttgagcagc aggttcttgc gaataaacta aacctgtagc
    60901 atgctcaggc gatttccctg aaaccttccc atagtggccc caaggggttt gagtaatggc
    60961 atcagaaaag gaaagttgct cttcttttaa gggattgacc cgaaaggccg aaaccgcttc
    61021 ctcctcaaaa gaggcaagaa aatctcttgc ctcatctcct agtatctctt tatatttttc
    61081 aacaaatcct tctggaaatt gcatttaagt tcttttcctt tcgtaaatat aggactgaat
    61141 ttcctcctgc atctcaagag gcaccatcat gaccggctgt ctggtttgaa aatcaggagc
    61201 ttcaccaaaa agggtcacaa cccgatagcc cagactttcc cctaaaatac tagctgcggc
    61261 ataatcccat ggttgcagat aagtgagata ggtcaacaaa cgccctgaca aaatcttggc
    61321 aaaactaatg gccgcacttc catagacacg aacaccaaga accgctcggc tcaaatcagc
    61381 cagcccccat tcattggttt ccagcatacc actattccct gcaatgagaa aatctccaag
    61441 tggtttagtt ttaaaaggag ctaggggcct atcatttaga caaactggaa attccccacc
    61501 accgtggtaa caatcccctt tgaccacatc ataaatcaga ccaaactgtc cctgaccatt
    61561 ttcaaaataa gccatcataa cagcaaaatc ttcctgctgg gctacaaaat tattggtacc
    61621 atcaatggga tcaatgaccc aaaccttgcc ctcttgaacc gaggctcgca gacaaccttc
    61681 ttcagcacaa atcttatcct caggataacg ggacaaaatc tcaccaacca agagttcctg
    61741 aacttctttg tccagtctgg tcaccaaatc tgttggagag gacttggttt caacacgcaa
    61801 gtcttcctgc atatggtcaa gaatgtactg acctgctttc ttaacaagct ctttagcaaa
    61861 ttcaaattta ctttccaaga gaaatctttc cttccccttt ttctttggca gcctgaactg
    61921 ctcggtaaag tgaatagcca ctaaccgttt caaattctcg tcccaaacgt ttctcttcgc
    61981 tcttgcttgg cacgaccgct ttgaatccct tataggagtc cagtaacttt ttagcctcta
    62041 ctttgccttc ataggcagct tcaacatcat taaaaaaaga aagcactgaa gcaagttctt
    62101 cagtgctcca cgacaaatct agtgggtaac tatactgttt gttcattaac taataccagc
    62161 tctcattctt gcttctttta gttcttgctt acgataacta cgagggagaa aagcacgaat
    62221 ctcatcttca ttaaaaccga tttgcatacg cttggcatca ataataattg gacgacgcaa
    62281 aagactagga tactgctcaa tcaaatgaag caattccgat accgaaatac tctctacatc
    62341 aatattcaat ttttgaaaaa tttttgaacg agttgaaatg atgtcatcag taccattttc
    62401 ggtcaaggaa aggatgtgtt gcaattcttt tcttgttaaa ggactggtca taatattgtg
    62461 ttccacaaag ggaaccttat gtttttctaa ccaggcctta gccttacgac atgatgtaca
    62521 gctcggtgat agaaatagtg taatcatgct tttctcttct tatctatact ttgctacttc
    62581 tattatacaa aaaaataagg cgcttgacta gggattttta gaaaaaaagc ctattttttc
    62641 aagaaaaata ggctgtttgc gaacgattga cacaattgga tttggttaat tcactcttaa
    62701 cgatggtttt aaacgatata tatttttata tatgcaaatt aaaaacatct ttcatttcac
    62761 ttcctacgac ttttcagaca cagatagcca aagaagcttt catagagggc aaaaaagagg
    62821 aggaaggcat gaagaaagaa ggtctctggc aaaatcataa taacaggatc cttggctgga
    62881 tcaaaaagcc aggtatcatc tcccacaaag agaatttgat ggaaaagagt aaagaattgg
    62941 tcaaaaccaa tcaaaactcc cccaagtcca atcatcacag gtaagactac tagagccagg
    63001 agactttttc gataaagaga caaaaagtcc tttttcacaa tcctattgac aaagacatag
    63061 aaacttggca gtgtcactag agctactagc tgaaccaaat gaaagagatt cttgaccact
    63121 gcgaaatggt gcagaccagc tgctgacgaa cgaaaatcag gcatctgtaa gacctgacta
    63181 aaaggattgg tcagataatt catcaagata tgaaaattgt attgaatggt ttctggtttt
    63241 agatagactc gattcgttaa gtttagccac tgaatctcca taggatagaa aatccaagcc
    63301 agataaatgg tcagaaggat tgagagggag aggagaaaga gcatagagcc ccaaaaggtc
    63361 aatttagttt tcatcaaaat cccactccgc aaggctagaa accacatgtg tcggtgcgat
    63421 tggcaggcca gctacttctt ctgccttggt aaaacctgtc gtcaccaaga gcgttggaat
    63481 gccattgtca atcccagccc ggatatcagt caaataattg tccccaacca tgattaactc
    63541 ttcacgttcc aaacctaagt gctcaaccgc cttgtccata atgatggcat ttggttttcc
    63601 gatataaacc ggcttcactc gtgtcgctac ttcaagcagc gtaatcagtg agccagcacc
    63661 tggcaaaaga ccgcgttccg tcgggatgtt gaggtcagga ttggttccga taaaatgggc
    63721 acccttttga atagcaagag ttgctgtggc aaatttttca tagtcgactt gccaatccag
    63781 accaactacc acgtaggcag gtttttcctt gtcttccaca taaccagccg ccttgatggc
    63841 ttccttgagt cctgcttctc cgacgacata gacggtcttt tcaagcccca aatcattcat
    63901 atagtcgatg gttgccaaag tcgctgtgta gacagtcgat aggggcgtat cgatattaaa
    63961 attctgagcc aacatctcct taacactctc tggagtgcgg gttgtattgt tggttacaaa
    64021 gagataggga atgtcccgct tttgcaattc atgaacaaaa gtctctccag cagggattcg
    64081 gtctttcccc ttataaatgg ttccgtctaa atcaattaaa tagcctttat atttcatcta
    64141 tttctcccta agcctttttt atttcttgcc aagtaatgat tgcttgggca ttgataaccc
    64201 catcacttgt aatttcatgc ttgctttcca gtccagtccg ttcaacagcc gatgtaatca
    64261 ccccacctgg tcgaacttcc ttgacatact tgaggttgat tttcttggga atatagtggg
    64321 tcaaaaaatc cgctcccatg agctcaaaaa tccagtccaa gtatttactg ttattgacat
    64381 gaccattcat atccaagtcg taaaaacgaa catggtaatc cttgctgatc ggttcttcca
    64441 aggactcata cttcggtcca cggataagtt ttttatcaaa atcagactgg taaggagcca
    64501 caatctcagg ttcaacaaca tggacttttc gactgtcgcg gtccatgaga acaaaggtcg
    64561 ccatcatgtg gatgagctcc tgctccgctt cattataaat agtaaagcga cggtagcaaa
    64621 aaagtcgatt gtagctcaag gcttccgttt cgatggtaat ttcttccgca aaacgaggca
    64681 aacgaaccac ctcaatatca tattctacga taatccagac cagattatat tcttccaaaa
    64741 tggccttatc actaactccc agttcaatcg actgcatccc tgaaacttgc agtgacagca
    64801 aaatcacatc tggaagtttg atatgaccgt tcatatcagc catatcaaaa ggaattttca
    64861 ttttcatttg ataagttaag cccatgatcc tactccaaaa taaatcgttc tgctacagta
    64921 tctcccaaaa agagacctct ctttgtcatg cgaacgtggt caccctcaat ctgcatgagg
    64981 ccttgttgaa ccaaatctct gacaatttct ccataaagtc cagcaaaaga ctgtccaaat
    65041 ttttcctcaa atcgcgccat ggaaaccccg gatttcttgc ggagtcccaa gaacatttct
    65101 tcttccattt gctccttttg actcaggtga tcttctgtaa tacaagcatt gccttcctca
    65161 accgcactga gataatgacg aatgggacca tgatttttat agcgtactcc attgacataa
    65221 ccagatgccc ctgcaccaat accatagtat tcagcattgt cccagtacat gagattgtga
    65281 cgactttcaa aaccgggttt ggagaaatta gaaatctcat aatgctcaaa acccgctcgc
    65341 tccagctctg caatgatgta ctcaaacatc tccgcttcta gttcctcctt aggcagaggc
    65401 aatttcccac gtcgcatccg gttcataaag accgtatggt tttctaaaat caaactatac
    65461 aaactcatgt ggggaatatc cagtccaatg gctttagcca cattttcctt tacttgctcc
    65521 atggtctgac caggcagagc ataaatcaaa tcaatggaga tgttgtcaaa accagccagt
    65581 ttcagacgat cgatattttc ataaatatcc ttctccaaat gactgcgccc aatctttttc
    65641 aacatcttat catcaaaggt ctggacacct agcgaaacac gattgacagc cgaatttttc
    65701 aaaacagcta tcttatccgc atccaaatcg cctggattgg cttcaatggt caactcttcc
    65761 aagacagaca agtccaagtt tttagtcaag ccattcagta acacctccag ttgcggagcc
    65821 gacagggctg tcggtgttcc accaccgata taaagggttg acaacttttc aatatcataa
    65881 gaacgaaact cttccagcag atgctctaaa tagctgtcga ctggctgatt tttgatgaag
    65941 acctttgaaa aatcacaata ataacaaatc tgggtacaaa atgggatgtg cacataggct
    66001 gacgttggtt ttttctgcat agtaattatt ataccacaaa gactagattc cagataaaaa
    66061 tcaccatccc cagatacata gtccgtccgg agatggtgat ggtttattct tctgttatat
    66121 caatcacaat ctcttctgag tcatcaagag cttcggcttt ttcttgccat tgttccttga
    66181 gattatttaa ttgatttttt gatgcttctg tcgcttgaaa agcataggat ttagcttgag
    66241 caagtatact gtccacagtg atttcacctg actcaacctg ttcttttgtt ttcagaacaa
    66301 aatctgtagc ctgctcctta acttctgtca gtttttcaca gacttgctcc ttggcatact
    66361 ccggatcttc tctcaaatca tctagaaaat cttgagcctg actgcaaact tgtttgccct
    66421 tatcacttgt taaaaacaag gcaagagctg cacctgaaac cgttcctaaa aggattgagg
    66481 ataatttacc cataaggatt ctcctttttt attttttgaa aaatttactt gcaagacgaa
    66541 gagctgacag acttgcacca gtcttgagtg tttttgaacc agctgatgaa gctttcttgc
    66601 tcaagacacg cgcatggtca ttgaggtctg aaacagatag agataaatct gcaacagcac
    66661 tgaagagtgg atcaatcgta gccaccttga cattgatatc atctgccaag acattgacct
    66721 tagccaacaa ctcattggtg tgatgcaagg tcacatccac atctgaagtc aaggttttaa
    66781 tcgtcttttc tgtttcatcg atgacacgac caagcttttg tacagtaatg atcagataga
    66841 ccaaaaagac aattaaagct agggcaacaa gaatatatgc aacttctaac atttagtttt
    66901 cctcctctgt aatatagtaa ggggccttct ttcgattttg ataaataacg atcattatac
    66961 cgagaccgat aaggacaact gacagccatt gggacactcg aaggccgaag aacatgagac
    67021 tatctgttcg cataccttcg atgaccatac gaccgaaacc ataccaaatc aagtaaaagg
    67081 ccgtgatatg acctcgtctg agactcttcc atttccgtct aaaaatcaga atcaaggcaa
    67141 agccaagcag attccataga gactcataaa ggaaagtcgg ttgacggtag ctcccctcaa
    67201 tatacatctg gtcacggata aagccaggta gataatccag attatccact gttgcaccat
    67261 aagcttcttg gttaaagaaa ttaccccaac gccccaaact ttgagcaatc ataacgctag
    67321 gcgccgcaat atctagaaaa tcccaagtat tgatgagttt acggtcagca aagatataga
    67381 gcacaagagc cccagttatc aaaccaccgt aaatggccaa accaccattc caaatggcaa
    67441 aaatctctcc taaattctga ctatagtaat caaatcggaa aataacatag tagagacgag
    67501 ctcctaaaat agccaaggga aaggctacta agataaaatc taaaatatcg tctggtatga
    67561 tcttctttct aggtgcttct ttcatggtca aataaaccgc aagaatcaag cctgtcacaa
    67621 tacataaggc ataccaacga atagctaggg gtcctagttg aatagcaatt ggatcaagca
    67681 ttttgcacct catttcgagc gatgagactt gtcagtcgtt cgtcgaacaa acgggtcgca
    67741 tcaaagccca tttccttggc acgataattc atggcagctg cctcaatcac aacagagata
    67801 ttacgacctg ttttaactgg aatacgaata cgaggaatgg ctacgccaga aacttcaagt
    67861 tcctctgcat tgtttccaag acgatcaaag gtcttatgcg tatcgtaatt ttccaaatag
    67921 acagcaagct gaacctgtga agaatccttg acagcactcg caccgtagag actcataaca
    67981 tcgataatac caaccccacg aatttcaatc aagtgtttca aaatttcagc tggttcaccc
    68041 cagagagtaa tctcatcctt ggcaaagata tcgacacggt catcggctac caaacggtga
    68101 ccacgtttga caagctcaag acctgtctcg ctcttaccaa ttccactatc tccctgaatc
    68161 aagacgccca tcccataaat atccatcaag acaccgtgca cactggtacg ttctgccaaa
    68221 cgagaatcca gatagctaga taactctcca gataaacgac tggtagctgc acggctggtt
    68281 aaaatagcaa tcttacattc tctagcagcc tttaacatct cctctggaac caccaaacca
    68341 cgagcaacaa tgactgctgg tgtctcaggt agaaacattt ttttcaaaac ttcataacgg
    68401 ctgttggaag gcatgctgat cagataagac cactccttca tccccaaaag ttgaatccgc
    68461 tctggtgtat agtagtcaaa atagcctgtc atttcaagac caggtcgcgt aatatccgct
    68521 gtattgattt ccttttcaag caactctggt tcaccataga caatgtctag tctaagcttt
    68581 tcaatcactt cttttactaa aaccgacatc atttcctcct tcaaatgagt tcttctctct
    68641 attatatcaa attgtaggag gaagtttcag atttttgcag gctttggagt atttatttaa
    68701 aagaaaaagg actagatttc tctagccttt catttcaatt agaatttttt acgtttacga
    68761 gctacttctg atttacgttt acgttttaca gaaggttttt catagaattc acgtttgcgt
    68821 gtttcttgaa gagtaccagc tttagtaacc gcacgtttga aacggcgaag tgcgtcgtca
    68881 agagattcat tcttacgtac tactgtttta gacatttttt tcactccctt caagttcaat
    68941 atctatttca ttctacacgt aaaaggaata attgtcaagc aaaaatgcgg tttaattttg
    69001 attttttctt ccatttatac aagagttgaa agcgttcaat agaacattgc ttttttattt
    69061 ttcgagtaag ctaagcgctt cagcatctgc gatgatggtt acatcagggt gattttgaag
    69121 gctacttgca ggtaggttct cagtcactgg gccagatact gttccggcaa tggcttctgc
    69181 tttcgactca ccgtaagcaa aaagaataat agacttggca tccaaaatgt ttttaatccc
    69241 cattgaaata gcttgggttg ggacgtcttc aatcttggca aagaagcgtg cattggcttc
    69301 gatagtagac tggtcaagtt ctactagatg cgtttgactg tcaaatggag taccaggctc
    69361 attaaagccg atatgcccat tgcgaccgat tcccaagatt tggaggtcaa ctggatggtc
    69421 agccaaaatt tggttgtagc gttcaacttc agcttcagca ttgtccttaa caccacgagg
    69481 caagaaactt tctttaaatg gtttttggtt gaacaagttt tcttgcatga agtaacgata
    69541 agactgtgga ttgtccccat caaggcccac atactcatca aggttgacac tggttagatt
    69601 tgaaaaatca aggtcactct caacaatttc cttgtaaaat tcaagtgggc tacttcctgt
    69661 cgcaagtcct agagtttgag ctccattagc caatttttcc ttcaaaatct caaaagcaac
    69721 ttttccacct tgaacttggt tttcaacttt aataactttc atcttttcat cctccatttc
    69781 tgtctatatt tattatatgg tatagaccaa tttttgtcaa gtgaaaacga tttaatttct
    69841 aaaaaaagag cgtccaaact tgaaacgtgt tataatggat aggattataa cttagaaaga
    69901 atgaacaaat atatgaatac agctgatttt gatttccact tgccagagga attgattgcc
    69961 caaacgcccc ttgaaaaacg tgatgcctcc aaactcctca tcgtcaaccg tgagacagga
    70021 gaaatgcaag ataaacattt ccactctatt attgatatgc tggaacctgg tgatgccctt
    70081 gtcatgaacg acacccgagt tctccctgcc cgcctctatg gtcaaaaagt ggagacagga
    70141 ggtcatgtgg aacttctcct ccttaagaac actagtggag acgagtggga agttctggct
    70201 aaacctgcca aacgcctcaa ggtcggtact cgtatcagct ttggtgatgg ccgcctcagc
    70261 gctgtcgtta cagaagaatt gacccacggg ggacgcattg tccgctttga ataccaagga
    70321 attttcctag aagtcttgga aagtctggga gaaatgcctc tgccacctta tatccacgaa
    70381 aaattagatg accgtgaacg ttatcaaacc gtctacgcca aggaaagcgg ctctgctgca
    70441 gcaccgactg ctggtcttca cttcaccaaa gaactgctgg cagaaatcca agctaagggt
    70501 gttcatctag tctatctgac tctccatgtc ggactcggaa cctttagacc tgtttctgtg
    70561 gataatctgg acgaacacga aatgcactca gagttctatc aactttctga ggaagctgct
    70621 gccacccttc gctctgtcaa agaaaatggt ggtcgcgtca tcgctgtcgg aaccacttct
    70681 atccgcacct tggaaactat tggttccaag tttgatgggc aaatccaagc agattctggt
    70741 tggaccaata tctttatcaa acctgggtat gagtggaagg tcgtggatgc cttctcaacc
    70801 aacttccatc tgccaaaatc aactctggtc atgttggttt ctgcctttgc aggccgtgaa
    70861 ttagtcttag atgcctacca ccatgccatc caagaacact accgcttctt cagttttggt
    70921 gacgccatgt ttatttattg agaaagaatt tctctaattc ttctaatacc aataaatcgc
    70981 taagatatta tttcaaagaa catctacaat tgaaactcta gctagctgta gaagacgcct
    71041 agtacattga aattaaaatg cttcccccta gcttcgaaaa tattgccata gattgcgttg
    71101 actctccaaa ttgattcatc tatattttat ttcagcttcc tatattttct tcgctgtttg
    71161 taaatcaaaa tgcaagacac atgagtagca ccatatttgt tactcttatc tgtcctctca
    71221 agagactatt atgagttatt tcagaatcat tcactacttt gaccctgact ctccttagtc
    71281 tcaaaatcaa agacttatac tcttcaaaaa tctcttcaaa ccgcgtcaac gtcaccttgg
    71341 attatatatg tgactgactt cgtcagttct atctacaacc tcaaagcagt actttgagca
    71401 acctgcgact agttttctag tttgctcttt gattttcatt gagtattaaa caaaaagtga
    71461 acaaatctga attctaatgt acagaagact aggcttgttc acttttttat agtcgctata
    71521 agatgacctt atctatagct ttttatatat aattatatat tcagacatac tattatcaat
    71581 tttgtcgcag ggaggaatct gttaacgcac ccattcacca ttatcattga ctctatagcc
    71641 atctatactt gtattgaccg ctaactcacc cgatgcattt acataatacc atttaccacc
    71701 aacttggaac cattgattga ctttcataga accgttgctg ttgaggtagt accatgaacc
    71761 attaacttgt acccaacctg ttgccatgga accatcagta ttataaaaat accacatacc
    71821 attttcttgt ttccagtctg ttgttggagc aactgcttta gctggttcta ctgctacatc
    71881 tgttccttgg ttagatgtaa cagatacagg atacgaagga atagatgatt gctcaggaac
    71941 aacaactttt tcaggttctc tcgtccctct ccttatacgt ctttttacca tctctttagt
    72001 aatttgacga gaagtagttt cttcaattgt tccatcacgt tcatctacag tatagattgt
    72061 agtaagagta atttaccaat ttctcctact tcttctactt cttgactttt atcaagagtt
    72121 gggccatcga gatattctgt ttcgattgga atttcttgga caagaacttg gggcttggtt
    72181 ctttttttaa caactcttgt ttgagagtct ttttttgact taaagtactc tcagttactt
    72241 gtccactctt tccatctaca ttataagtta tcgttgtaac tgttttccca ttctttccta
    72301 gagtaatctc ttgctcctgt cctgcagaaa ggtcattgtc tgcttcatat ttagtagcaa
    72361 atggaacaag aacttcttca accttgcttt tagctggaac tttgataact gtatccgtgg
    72421 cttcttttct atcaacagta acctgttcgg taacataacc agtctctgga ttaacatcgt
    72481 aggtccttgt cgtagttaca tagccatcct ctccatcaat tgtaacagga ttttcactac
    72541 ggtcttttgt ttcatctttt tcataacgaa ttcgcgtact tgaaattttc ttggttacta
    72601 ccttaggttt agtcgctact tttacaataa tatccccatt gtcagcgtca tcatactcta
    72661 ttccctcttc tttatctcta gtatcatctc tgacatattg aatcccatca gcagcatgaa
    72721 caaaacttgt attcagattc ctcctaaaaa taaagttagc ccgattaccg cagaaccaaa
    72781 aatctttccg agtttacgta ttgcatagcg cttattagta ttagattttg ccattacatc
    72841 ctacttctag tatagcatct tttctatcaa acgttaaaca atatacttta tatataaaat
    72901 agacttagaa tgatatattg attattgaac taacacttta actatatcgt aatcaatctc
    72961 atatataaag gattgcagac atcttatcta aatacatgct aatatattta gatacaaaca
    73021 ttccaacttg ataattttca ctcatctttc atcattcctt atacaactat gcagtataaa
    73081 tagaatagtt ttctcatcag aatgagacta ttttaatatt agataatttg atagaaaaaa
    73141 catgaataaa attggttgaa tttaattccc taactcgata gaggattcta ttttaaattt
    73201 aacaacagct aggattacac tataaaaagt acattaccac ctgttcggct ggagaatcta
    73261 gtcgattagc tccctcttag ttacaagctt caagcgattt tttaactaac actaaaccag
    73321 attaaagaag gaactagaac atctgtcttg tactaatcaa tatgctattt taaagtttca
    73381 aataaacttg gaatgctaat tattatattt acaataaata gttgacttcg atagaaacag
    73441 aaaatagaat tcaacattct tccctactta taccataata aataagatcc gcaagatagc
    73501 cttttctctc tacaccatta acaatggttt gtagatagga cattccagcc ttttccatga
    73561 cacgacctga agctgggttg agactggcat aacgtgctct gaccttttga aaacctgctt
    73621 gagtaaaaca aaagtccaag atagctttca aagtctctgt catcatacca tttccccagt
    73681 aagccttgcc taacacatag ccaatttcac agcttaaatc agcctcgtct atcttaacaa
    73741 tgctgatatc tcctattact tgctctgggt tttcttttag acaaatggcc catttataat
    73801 agttgagatt agtataggaa gcaacccaat tgcaaatcga gtttcgagtg atttcgacat
    73861 caggatgggg atcccaggta acataggtca gattctcagc ggatgaagcc caattttgaa
    73921 acatggcttc tgcatcactc tccacaaatc ttcttaaaat caaacgttct gtctgtaata
    73981 tttgcgtacc gatagatttc atgatgctac ctcacttcct tatttctata ctcgtagtaa
    74041 aaaggctcaa ctcagtaaca gctagaaaac gagtttgtct tctaatttct tgacgcagtt
    74101 gctgcctggt ttgaaatgcg ctctagcaag ctttttcaaa cctagtcatc gttgcagggg
    74161 taagacgatg aaatcgaact cttcgagtta ctgaatctgc ctcattttct tatttctaaa
    74221 ctcggggttc aagatccccc agaccttctc tcactttctt atttcaagat gagaggctga
    74281 aaacctccag tggaggtttt tcttgctttt taatttcagg gcaagaagct aaaaaggtcc
    74341 cccggacctt tttactccca aaagtcatca aatacggtga tgggtaagtg gcgtttgtgt
    74401 tggcctttgt gccaccagtt ttcaatggtc gcttgagctt ctgggctgat tgttttgcct
    74461 tctaggtagt cgtcaatctc tgcgtaggtg actccaagtg cgacttcgtc agctaggcct
    74521 ggtttatctt cttctaggtc tgccgttggg attttttcat aaagggctgg ctctgcgcca
    74581 agtttctgca agagctgttt tccttggcgt ttattgaggc ggtaaagagg gagaatatcc
    74641 gcaccgccgt caccaaactt ggtaaagaaa cctgtgatat tttccgcggc gtggtctgtt
    74701 ccaatgaccg ctccgctatg ggaaccagca agggcatact gagcaatcat acggcaacgt
    74761 gccttgatat tccccttgtt gaagtctgaa acaggactac ctgtcgcttc aactgcagct
    74821 gtcatggcat cagctgattc cttgatattc acaaccaagc tgacatctgg ctggatgaag
    74881 gctagggctt tttgagcatc tgcttcatca gcttgcactc cgtatggcag gcggacagcg
    74941 ataaatttgt agctatcgtc tcccgtttca gctcgcagtt cttccatagc taattgcgcc
    75001 aaacgtcctg ccaaggttga gtcttgtccc ccagaaatcc ctagtacaaa ggtttttagg
    75061 aagggatgtt ttttcagata tctttttaag aaatcaatag aacgacggat ttcttcctgg
    75121 gcatcaatca ctggtttgac acccagctct tggataatcg tttcttgcaa actcattctt
    75181 cttctccttc accaagggct tccttgcgca tcttatcaat caagtccatc ttatcttgcc
    75241 atacatcacg cgccaaatcc actggatagt gctgcggatt gagcacacgc ttatactcat
    75301 cccacaactt gtcaaattcc ttacgggcat aatcctgaat gtcagtcaaa ctaggcaagt
    75361 tgtaaactaa tattccttct ttgaagatat ccaccaagag aggaacggca tcaaaattac
    75421 gaaccgtctt cttgatgtat gtataggtcg gatggaacat cttgatttct gtcatgtcgc
    75481 taatatccac accatcataa gtgatatagt cgccttctga cttgcctttt tcacgactgg
    75541 taatgcgcca cacctgcttc ttacctggcg tagaaacttt ttcagcatta ttagacagct
    75601 taatcgtatt gcgcatctga ccagtttcat cttcgattgc aacaatcttg taaaccgccc
    75661 caagagccgg ctggtcatag gctgtaatca gcttggtacc cacaccccag acatcaatct
    75721 tggccttttg catcttgagg ttaaggatgg tattttcatc tagatcatta gaagcataaa
    75781 tcttagcctc tgtaaatcca gcctcatcca gttgctgacg gactttctta gaaatgtagg
    75841 caatatcccc agagtcaatc cgcacaccca taaagttaat ctgatcaccc agctcacgcg
    75901 ccacctgaat ggcagctggt acaccgatgc gaagggtgtc ataggtatcc acaagaaaga
    75961 cacaattttt gtgggtcgca gcgtaagcct tgaaagcttc atagtcattg ccataaacct
    76021 gtaccaaggc atgggcatgg gttcccaaaa caggaatgtc aaagagctta cccgcacgca
    76081 cgttgctagt tccattggcg ccaccaatca cagctgcgcg tgttccccag atggccgcat
    76141 ccatttcttg agcccgacgt gtcccaaact ccatcaaggg ttcatcttcg ataaccgaac
    76201 gaatacgagc tgccttcgtc gccaccaagg tctggtagtt gacgatgttc aaaagagccg
    76261 tttcgaccaa ctgacattgg gctagaggtc cttccacctg cacaatcggt tcattagcaa
    76321 aaaccaaatc cccttcttgg gcagaacgaa cggtcaactc caacttgaaa ttgcgaaggt
    76381 aatccaagaa cgccccatga taaccaagcg actccaaata ggctatatca ctatctgaaa
    76441 aacgcaagtc ttcaagatag ttcacaattc tttccaaacc tgcaaaaacc gcatagccgt
    76501 tcttaaaagg ctgttggcgg aaatacacct caaagaccgc cttcttattg tgaatccctt
    76561 ggtcaaagta aacctgcatc atgttgatct ggtacaagtc cgtgtgcaat gtcaaactat
    76621 catctggata catacttttc ctacttcctt agctagaaac ccatgaaaat tttcaagaac
    76681 tttcatgtat tccaataaat tagtactatt atatcacatt ttagctggat tgagaaaaga
    76741 gtaacaagct attctccact ctccaattca tccatatctt gttcaaattt tttctgagcc
    76801 cattcgccat agctcttaag accaagattg ccaataaaga tccacggaag gtaaatgata
    76861 taagtaatga cccaagcaga caggtattta aaattcaaag gattgtgctg ataaatttct
    76921 atgttgaatt gataattctg caacatcaaa agagccgtaa tagccaaggt taggaaaaaa
    76981 caacccaaaa tcgtaaaatg aaaacgacta tagtaggtca ctcccagata acgggcacga
    77041 ttgaaaaagt aaaatgtccc tatgatgata acgattagca gcatattaga attaaaaagg
    77101 cttggtgcta atactgaaat gatataagat aggagcgaca aagcgatgca gatatagaaa
    77161 ctttcagagc ccgctttatt gaacagttgt tcttctcttt cgtctagtaa ttgataataa
    77221 taaaatctat ttttcatctt cttcctccca aaatagttgg tctagggttt tccctaaaca
    77281 tctgcaaatg gactggcaga gcgagagact gggattgtat ttccccgctt ctatcaaacc
    77341 aatagtctgg cgcgtcaccc cgacagcctc tgccagttga ccttgtgtta aatcacgctc
    77401 tacccgagct aattttaatt ttaaattttt agccaccttc gtcctcctta tagttttaat
    77461 actcatctac tcttaaaaaa tccaaaacca acacaagcta tcagctattt attataaccc
    77521 cattaatttg cactccagta ttatcttcag ccgaaaatca gtattttagg ttgtttgaaa
    77581 taaacttcct agtttactct tttattttta tttagtatta gctttagtag gatcttttaa
    77641 acgagttttt attgcttata tttcttgttt agtttagttg gtttcatatc actattatat
    77701 aatgcttttg gaaatgagcc tagtataagt caaaaacgtg ttgaatagtg aaagcaggag
    77761 cataccaaga tgactgattt ttttattgta ttttaggtat gcaaaataat actaaatgaa
    77821 actaaaatga atacttcttg cttttcttga gagtgaaaaa gtacaataaa atgattgtag
    77881 tgattaccac aagatactga ctaatagaca tcgtatttga agccacaaat acaggtaaag
    77941 aataaaaagg aagaagttca attgctttga taaacaaatc attactagta ttcatcatca
    78001 tcgtatttaa tatattaggg ataaagagta gtaaagctac taaaatacca aataccaagc
    78061 cacttttcaa tttgtataaa taaaaaatgt aagataatag aaaataaaac aggactaaca
    78121 aaattgtatt gactacaata gctactataa aatctaatcc taaatcacct ggaataccca
    78181 atttacttac tatgactagt aacacaatgc cattcaaagc ataaataatg gaaactgaga
    78241 tggcatatag aaaattagac aagacgtaaa tcatccgatt cttctgttta tttaatttca
    78301 tgattataac cttcctttat tttgaacgat ttaggtaaat atctttaagc gtctcttttt
    78361 tagtttcaaa atcaactact ttaatagagt tttcgttaaa aaatttaaaa agctcactat
    78421 tttgaatatt cccagacata gtaattctca atccctcttc ctgaacaata tccccaaatt
    78481 cttgtttggt aatgaaaatg tctctatctg tagctgatga aaaagctatc tcaaacaaga
    78541 aattatgact atcttttcct actttttgaa atgtcaaaag cccgctctcc aagaaaagaa
    78601 ccctctcaca aatttcttca atgtcttcta atttatgact cgatattaaa attcccacgt
    78661 tttcatttaa agctaatttt ttttagaacc gctaaaacta tttgtgatga ttcaatatct
    78721 aaaccattag tcggttcatc taaaatcaat atatcaggtt ccgtaacgag agttagaagc
    78781 aaagctaatt tttgttttgt acccaaagaa taggtcttta cttttttatt aatagactga
    78841 gtcaaatcta actcttggat caaacttcta aatctttctt gattgtagtc aacaccatat
    78901 aaatttgaca aatattttaa attctctaaa cctgttttag ataaaaataa ttttggttct
    78961 tcgattaaat acccaacatt atcactgttt ataatattac ctgaagtcgg ttgattattt
    79021 tgaacaagaa ttttcatcaa cgtactctta ccaactccat ttctccctac tagaccaaca
    79081 atttcaccct tgttaagtgc aaaatttata tctttgagaa tgattgaatg accataatgc
    79141 ttacttacat ttataactta cattttttat tcctccatta atattcatgg tttgctcttt
    79201 gattcttatt gagtttaaaa agttgcgcct ctttttaaca atattatatc atatatctaa
    79261 cttaatgcaa tatataaatg tcattttgta aaattttatt aacaaaaaac tctctacaac
    79321 aaaataatag agagttttct gcttattaat ttttttcaaa atatctaaga catcgcttct
    79381 ttgtttaatt tgataggctt taatacctaa gctccgactt tatcacttaa aaaataaaaa
    79441 aggacagcta atctcttgcg catcaaggga tttcgccatt ctttaatctc gtttaagtgt
    79501 tgtatatgga gctttgcata attttttaaa actaaacaac tacattaagc acgaactgtg
    79561 acgctggttc catcttcctt ataaagattg ataagcccct ctttaagagc tcgaaccatg
    79621 tctccagctt gaacaagttg tgggacttta atagtcaata gttccattgg atttggagcg
    79681 cggtcgattt tattgccttt ggcatcatgc aaatcttcaa tataggtttc aaaatgacgg
    79741 aaacctggac cataaaactc aacttggtcc ccttcgttaa tgacgttccg ttgacgaatg
    79801 gttgctgttt gtgtcgcatc atcataagaa accacttcag cgacaaactt gtactcaggg
    79861 attttacgac gagcaccaaa caactgctca ttttcagatg gtgtaccata gtaaaatcct
    79921 gtagccagtt cacgttgggc aaccttccac atctcgtcca ccaagtcttg tttgatagct
    79981 tcaaactttt caggactttc aagataggca tccacagccg ccttgtagca gttggttact
    80041 gttgatacat agtgaataga ctccatacgt ccttcgattt ttagactgtc cacaccattt
    80101 tcaatcatat ctgagatatg gtcaatcata gacatatcaa cggctgacat tgaaaattct
    80161 tctggaatct caccctgcaa actcttacgt tctttcccaa atggcatatc gtaaaggtcg
    80221 tacttccaac ggcatgactg agaacatcca ccacggttgg catcacgcat actctagacg
    80281 gattgttttg acaattctaa ccttttagac tttgcataat aactgttaaa cagtcgaaaa
    80341 ttaccccagt tttaacaagt agtcaaaata ccagataaag taaaaagggg ctaggaaaaa
    80401 agtctttaaa atcttaaaaa cgcatagtat caggtattga acaatcttga tattatgcgt
    80461 tttattgtgg gaagatttac ttcattttct cttggaattg agttttctcc tacttcaaaa
    80521 ctagatgatt tgctatttaa aatagcgttc cttatgattt tggcaacctg gattaaagcg
    80581 agaaaaacaa aaggggcaac ttaagctttc tttatattgc ttatatgtta gtagttttag
    80641 acaaacacca cataaaatag gcttatcctg tatcaaagat aagggatacg gctcaaaagg
    80701 gtgattttct aatgaatcat gacaccgata acaagcataa tactttttac aatcatagca
    80761 ttgtaaagca ataatatcca gcttgctatg gtaatgaatg catcttgttt gcttatccac
    80821 taagaaaccc tgtgcctcta tcatttcctt ttcctttctt aagctcgaac tgtgacgctg
    80881 gttccatctt ccttataaag attgatgagt ccttctttta atgcacgaac catgtctcct
    80941 gattgaacgg gttgaggcac cttaatagtc aatagttcca ttggatttgg agcgcggtcg
    81001 attttattgc ctttggcatc atgcaaatct tcaatatagg tttcaaaatg acggaaacct
    81061 ggaccataaa actcaacttg gtccccttcg ttaatgacgt ttcgttgacg aatagttgct
    81121 gtttgtgccg catcatcata agaaaccact tcagcgacaa acttgtactc aggaatttta
    81181 cggcgagcac caaacaactg ctcattttca gatggtatac cgtagtagaa acctgttgcc
    81241 aattcacgtt gggcaacctt ccacatctcg tccaccaagt cttgtttgat agcttcaaac
    81301 ttttcagaac tttcaagata ggcatccaca gccgccttgt agcagttggt tactgttgat
    81361 acgtagtgaa tagacttcat ccgtccttcg atttttagac tatccacacc attttcaatc
    81421 atatctggaa tgtggtcaat catagacatg tcaacggctg acattgaaaa ttcttctgga
    81481 atctcaccct gcaaactctt acgttctttc ccaaatggca tatcgtaaag gtcgtatttc
    81541 caacggcatg actgagaaca tccaccacgg ttggcatcac gcatactcat gtggtttgaa
    81601 agagtacaac gtccagagta tgaaatacac atagctccat ggacaaaggc ttcaatttca
    81661 acatctgtac gtttgcggat ttcagctaat tcttccattg aaacctcacg cgctaaaacg
    81721 acacgagtca agcctagctc tttccagaac tcaagggttt catagttagt ggcactggct
    81781 tgggtagaaa ggtggatttc aaggcctggt gcttcagtcg ctgcaatcat aatcaaggct
    81841 gggtcagata cgataactgc tgcaatcccg atatcacgca gtttacggaa ccactcacca
    81901 gcaccagctt catttccttc gtgcataacc atattagccg ctacatagac cttggcacca
    81961 tacttggccg caaactgcac gccttcttcc atctgttcga aagtaaagtt tcccgcacgg
    82021 ctacgaagac cataggcctg accaccgata aagacagcat ctgctccata ctgaacagct
    82081 acctttagct tctctaaagt ccctgcaggt gataaaacct caggacgttt taatgttttt
    82141 gtcatgattt ctcctatttg caatataaaa gtttgacatt tttccttctc attttatagt
    82201 aaataaagga taaaatcaag cctagacgga ttgttttgac aattctaatc ttttagactt
    82261 tgcataataa ctgttaaaca gtcgaaaatt atcccagttt taacaagtag tcaaaaagtc
    82321 tagaaaagta aaaaccagta tccaaagata ctgactcgta aaaatacata aattagtcct
    82381 tagatgacta ctcccactct gttgctccta taatggaaaa ggattgatac agtctagaat
    82441 atcgcttttt tatttattat tctgatataa aactgttaga attgattttt tgttttatac
    82501 ccaaatatga atagagacgt agctaataag ttgaataaca tatttggaaa aatgagaaat
    82561 agcaatatta ctagaacttt tagaaacaat caatatttaa aaagaaaaaa gctcaaagaa
    82621 tttattaaac catgttataa tagatatagc tataatttta tttataacaa gaggatagaa
    82681 atgaccgaat tagaaagaaa aaatcgaaaa attagctaag aaatattctg ataacttaaa
    82741 catcaaagtt caagagagag ttcgtgaaat ggcaaatgat aataagagcc attatttgat
    82801 atacagagtt ttaggtattt catttgaaga aggagaaaat atcgatttgt atcaaaataa
    82861 aggtcgtttt ttatacaaat atgctggttc atttttagaa gaagctgcag tactatgctt
    82921 taacgaaaaa tttggtacag aaaatactta aaaagttaac attcctaatt ctgaaagtac
    82981 aaaacctaag acttttgaaa ttgattgttt agtcggagaa aaacacgcat acgaaataaa
    83041 atggtgggat gcaactacag atggagacca tataactaaa gaacacacta gaataaaagt
    83101 tattcataac aaaggatata taccaattcg gttaatgttc tactatccaa atagaactca
    83161 agctataaaa attcagcaaa ctttagaaac attgtataac ggtattggag ggaaatatta
    83221 ttatggagat tctgcctggg aacatttaag agcagtgacc ggtattgatt tacttagtat
    83281 tctaacagat attgcaaata aaaaaacagg ggtaaaatca aaatgacagt attaaaagga
    83341 gataacttag aaatattaaa aactattgaa tcctcaagta ttgatttaat ctatatggac
    83401 cctcctttct ttacacagaa aacccaaaaa ttatctaata acaaaaatat tatgtattca
    83461 ttcgaagata cgtggacttc gattgaggat tacaaagaat ttttgtctgt aagattagaa
    83521 gaatgcaaaa gagtgctaaa aaatagtggc agtattttcg ttcattgtga taaaattgca
    83581 aatcatcata ttagattaat tttagataat atctttggag cagatatgtt tcaaagcgaa
    83641 attatatgga actataaacg gtggtctaat tcaaaaaagg gattattgaa caatcatcaa
    83701 aacatttact tttattcaaa gtcaaaagat tttaaattta atacaatttt tacagagtat
    83761 tcttctacta caaatatcga ccaaatacta gtggaacgaa aacgagatgg aaactctaaa
    83821 actatatata aagttgataa taatggtaac tatattctag caaaagagaa aaatggagtt
    83881 cccctttcag atgtttggaa tataccattt cttaatccaa aagctaaaga aagagtaggt
    83941 tatcctacac aaaaacctat tctgttatta gaacaaatta taaagattgc tactgataaa
    84001 aatgatatag ttttagaccc gttctgtgga agtggaacta ctttagtagc ctccaagatt
    84061 ttgaatagaa attatatggg gattgattta tctgaggaag ctatcaatat aactcagcaa
    84121 cgtctggaaa atgttataaa aacaagttca gatttattga ataaaggaat cgaagcatat
    84181 agaaccaaaa ctgaggaaga ggaaaacatt cttaaattat tacaggcaaa aattgttcaa
    84241 agaaataaag gaattgatgg ttttttacct aaacattttc aaaaaaaacc gatacctata
    84301 aaaattcaaa aaaataatga atgtctgaat gagagtatct ctttattaca gaatgctata
    84361 aactccaaaa aacttgattt tggagtagtt ataaaaactc attcagataa tttattattt
    84421 gattttgata cgattcctga aaatataata gtagttgacc attttgaact tacaatcgaa
    84481 aaatggttaa gtaaaagtta acagttacta tagtttgcaa attatttaca gaaagaacaa
    84541 aaatgctctg aaacactgat ttcaaagcat tttttgttag tttaaaatta ttcccactct
    84601 tcttttccaa acgtacaata tatccaaaac cattcaaaat actagattct attttttata
    84661 atatcactaa atccacctaa ttataggacg ttttcagatt tttagtcccg tcccagtccc
    84721 agtaccggag aaatattgtt ttaatataat atctcttttt gtcttctaag ctcttaaaag
    84781 caaaagaaca agtaaagagt caagacaagg ataaaaagtc catattaggg caaataaaaa
    84841 gctttaagac agatgacaaa tctaagtcaa ataagaaaga ccatagcaaa ggtgcagaga
    84901 gataaatatt ggcggtcttc ggactgcctt tattttttta tccatttttc aaatcaaatt
    84961 tattcagact atatatgcac atatacactt aaattcatat aaaaacatgg cttgtaaaaa
    85021 attactttaa tcacaataat cgcatttaaa attgtgatgt ttgcaagcta aattacggac
    85081 ttcacttgga agtttcccct tgtatctttt ataatagata gaaaatttgc tggcagatga
    85141 atatccaaca gattctgcta tctcttttat aggtagttca gtgtttaaaa gaagagtttc
    85201 agctacattc attctttttc tttgagtgta ctctgtaatg ctttgacaat atttttcctt
    85261 aaataaattt tttaatttag taccactcat tttagatatt ttttcaagcg tgccttgatt
    85321 tacattcgtt gcaaaatgat catctaagaa tcttgctaca tcttcaagtg ctttatcatc
    85381 atcaatttca attttatatt tttttctatt taagtatgtg tcaattacta tacttatcca
    85441 ttcatttgcc tttgctttaa agaaaaaatc agcggcagga gcgtccatct tacaatttaa
    85501 tatttccatt gccactcttt ctaaggcctt tgtaagtatt atttgattcg gttgaagcaa
    85561 ggttgaataa aaagattctg gattaatgtt aatagatgct aaatgttttt ctattagctc
    85621 ttttttaaaa ccaatggaaa cagcaagata acaacaattc tcgtgtaata aaaaaacaaa
    85681 atcatctttt atattatcaa aatcaaaagt acataaagag tttgcggtaa tagtttgata
    85741 cggattaaac ttttctccgt ttgcactgac aatgtaactt gaataaattg aaacatagtc
    85801 tgacatacta taagtgctat tttgaactac ttcctctttg ataaaaaaat catgtatatc
    85861 gataatgaag ctgcctcctt cataaaacca atataggcct tctgcataag ttgaattctc
    85921 ttttttccaa caaaatgtat gacctgcact tgaatacttc tcattgtttt tacattcatc
    85981 tactttcata taatctttta caaaatcata atatgacata acacactatc ccttttagac
    86041 aatattccaa ttagccttat taattcaaaa ctattgtatt agtaattata acagatgtat
    86101 aatagaaaag caatgataga tattatcaat taagcgaatt tatatctaaa agggatatta
    86161 aagaaaggag atatgcttat gaagatttac aaaaaactat ttgcttatgt ccaagataag
    86221 aaatatcttg gggttttggc cataattttt tctgctatat ctgctctact tacagtatat
    86281 ggatattatt taatctacaa atttctagat aagttaataa ttaattcaaa cttatccggt
    86341 gcagagagta tagcattaaa atctgttatt acactaacaa gtggagcgat attttatttt
    86401 gtctcaggaa tgttttcaca tatcttggga tttaggcttg aaacaaattt aagaaaaagg
    86461 ggaatcgatg gtctggaaaa agcaagtttt aggttctttg acttaaatcc atctggtcaa
    86521 ataagaaaga tcatagatga taatgcagca caaactcatc aggtggtagc acacatgatt
    86581 cccgatagtt ctcaggcaat aatcacaccc gtacttgtac ttgcacttgg ctttatagta
    86641 agtataaggg ttggcataat tttgcttgct cttactataa ttggtggctt aattttaggg
    86701 gcaatgatgg gcgagcaaga atttatgaag atataccaag aatccctatc taaactaagt
    86761 gctgaaactg ttgagtacgt gagaggaatg caagttgtaa aaatatttaa agcaaatgta
    86821 gagtctttta aaagctttta taaggcgata aaagattact caaagtatgc ttatgattat
    86881 tccctatctt gtaaaaggcc ttatgttttg tatcaatggt tattttttgg actgattgca
    86941 attttaatta ttcctatagt ttattttatg actagcttag ctagcgcaaa ggtgatttta
    87001 cttgagctta tcatgatttt atttttatca ggagttctct ttgtttcatt catgagaatg
    87061 atgtggtact ccatgtatat ttctcaagga aattatgcag tagatacttt agaggcgctt
    87121 tacgaagata tgcaaaaaga caaattagtg catggtaatg tcaataattt taaaaactat
    87181 aatatagaat ttgagaatgt tagctttgct tataatgata aagctgtcat tgaaaattta
    87241 tcctttaatt tagaagaagg aaagtcctac gcacttgtcg gttcatctgg atcaggcaaa
    87301 tcaacagtag caaaacttat atcaggtttt tacaatgtta ataaaggaag cataaagata
    87361 ggcgggatag caataagtga atattctgac gaagccttaa ttaaagccat ttcctttgtt
    87421 tttcaagatt caaaattatt caagaagagc atttatgata atgtagcttt agctaataaa
    87481 gatgcgacga aagatgacgt tatgagagcc ttaaaattag caggatgcga tttaatatta
    87541 gacaaattcc cagaaagaga aaatacaatc ataggctcaa aaggtgttta tttatccggt
    87601 ggagaaaaac aaagaattgc aattgctaga gcaattttaa aggattccaa aattattatt
    87661 atggatgaag catcagcatc tattgaccca gataacgagt ttgaattgca aaaagctttt
    87721 aaaaatctta tgaaggataa aacagttatc atgattgcac acaggctatc tacaattaaa
    87781 gaccttgatg aaattattgt catggatagt ggaaaaatta tagaaagagg gtctgacaaa
    87841 gaattaatgt caaaagatac aaggtataag agcctgcaag agatgtttaa cagtgcgaat
    87901 gaatggaggg tttcaaatga aagagtttta taaaaaaaga tttgctctta cagatggagg
    87961 agcaagaaat ttaagtaaag caacactggc ttcatttttc gtttattgta taaacatgct
    88021 tcctgccata ttacttatga tttttgctca ggaagttttg gaaaatatgg gcaaaagcaa
    88081 tggcttttat atagtattct cagttttgac tttgatagca atgtatattt tgctttctat
    88141 cgaatacgat aaattatata acacaaccta tcaagaaagt gcagatttaa gaataaggac
    88201 agcggagaat ttatcaaaat tacctctatc ttacttttct aaacatgaca tttccgacat
    88261 ttcacaaaca atcatggctg atattgaagg catagagcat gcaatgagcc actcaatacc
    88321 aaaggtgggc ggcatggtac tgtttttccc attaatatct gtaatgatgc tagcgggcaa
    88381 tgtcaagatg ggtttagctg taattattcc atctatttta agctttatat ttataccttt
    88441 atctaaaaaa tatcaggtta atggacagaa tagatattat gatgtcttaa gaaaaaactc
    88501 agaaagcttt caagaaaata tcgaaatgca aatggagatt aaagcatata atttatcgaa
    88561 ggatattaaa gatgacttat ataaaaaaat ggaagatagt gagagagtac acttaaaggc
    88621 agaagtaact acaattttaa ctttgtctat atcttcaata tttagcttta tatctcttgc
    88681 tgttgtgata tttgtcggcg taaatctaat tattaataaa gagataaatt ctctctacct
    88741 tataggatat ttactagctg ctatgaagat aaaagactct ttagatgcat ctaaagaggg
    88801 cttgatggaa atattttatt tatcgcccaa aatagaaaga ttaaaagaaa ttcaaaatca
    88861 agatttacaa gaaggcgatg actatagctt aaaaaaattt gatattgatc taaaagatgt
    88921 tgagtttgcc tacaataaag acgcaaaagt tttaaatggt gtaagtttta aagctaagca
    88981 gggagaggtc actgctttgg taggtgcaag tggctgcggt aaaacaacta tcttgaaact
    89041 tatatcaaga ctttatgatt atgacaaggg acaaatctta atcgatggca aagatataaa
    89101 agaaatatca acagaatctc tttttgataa ggtctctata gttttccaag atgtggttct
    89161 ctttaatcaa agcattatgg aaaatattag aatcggaaag caagatgcaa gtgacgaaga
    89221 ggttaaaaga gcagcaaaac ttgcaaattg cacagatttt atagaaaaaa tggataaagg
    89281 tttcgataca gttattggtg agaacggagc tgagctatca ggaggagaaa gacaaagatt
    89341 atcaatagcc agagccttct taaaagatgc gccgatattg atcttagatg agataacagc
    89401 aagccttgat gttaacaacg agaaaaagat tcaagagtct ttaaataatt tagttaaaga
    89461 taaaactgtt gtaatcattt cacatagaat gaaatccata gaaaatgcag acaagatagt
    89521 agttcttcaa aacggaagag tagaaagcga aggtaagcat gaagagcttt tacaaaaatc
    89581 aaaaatttac aaaaatttaa tagaaaagac aaaaatggca gaagaattta tttattagga
    89641 ggactacaat ggataataaa aaattaaaag taaaagattt agtaagtatc ggtgtttttg
    89701 gcgtaattta ttttgccttc atgtttggag ttggtatgat gggcttgatt ccaatattgt
    89761 tcttaatata cccgacagta ttagccatag ttgcaggaac tgttgttatg ttatttatgg
    89821 ctaaggttca aaagccatgg gcactattta tatttggtat gatatcacca cttgtgatgt
    89881 ttgcagctgg tcatacctac gtagttgtgg ttttatcact tatagtaatg ataatagcag
    89941 aattaattag aaagattggt aattataatt catttaaata caatatgctt tcttatgcaa
    90001 tcttcagcac atggatatgt agctctttaa tgcaaatgct tttagcaaaa gaaaaatata
    90061 tggagtggtc tttgatgacg atgggaaaag attatgttga tgtattagaa aagttaataa
    90121 cttatcctca catggcttta gtagccttag gtgctttctt aggaggaatt cttggagcat
    90181 atataggcaa ggctctattg aaaaaacact ttgaaaaagc aggcattgta taatgcctac
    90241 tttttcttca aatgctccct ttaatcccaa tccgatctct aagatattag tcgtatttat
    90301 cacaggctta actgttatgc atagcataaa catccgtttt gagctggcaa ttgtttgtct
    90361 tattggtatt ttgctttatt tgaatggata caaaaaaaca cttttcaaat ggattatatt
    90421 gtgtgggata ctttactcct tgcctaattt tatggtgtta tctgaattaa accctatagt
    90481 taagatgttt ttgagtatac ctattgttat tagaatgttt attttaccat ttatggcagc
    90541 aagctttatg ataaagacct cggatgtagg cgcaataatt tcatcgatgg ataagcttaa
    90601 gatttcaaag aatgtatcca tacctattgc ggttatgttt agattcttcc catcttttaa
    90661 ggaggagaag aaaaacatca aaatggctat gagagtaaga gggataagtt ttaaaaaccc
    90721 agtcaaatat cttgaatatg tttctatgcc actactcatt atatcatcta atatatcaga
    90781 tgacattgca aaagcggcag aaacaaaggc aatagaaaat ccaattgcca agaccagata
    90841 cattcgcgta aagatacagc taattgattt tgtttatgtt ttagcggttg ctggacttat
    90901 tgtgggaggc ttaatatggt tgaaataaaa aatttaagtc ttgattatgg tgaagagcat
    90961 atattagatg atatatcact atccatagcc gagggagagt gcgtgctatt tacaggaaaa
    91021 agtggaaatg gtaagtcatc tttaataaat tcaatcaatg gactagctgt aaggtatgat
    91081 aacgcaaaga caaagggcga aataattatt gatggtaaga atataaaaaa tttggaactt
    91141 tatcaaatct caatgcttgt ttcaactgtt tttcaaaatc ctaagacata tttttttaat
    91201 gtcaatacga cattagaatt attattttat ttggaaaata tcggtcttgc aagagaagag
    91261 atggacaggc gtttgaagga tatgcttaag atattcccga taaaaaatct tttgaacaga
    91321 aatatattta atctatccgg cggtgaaaaa caaattcttt gcattgcagc ttcttatata
    91381 gcaggtacaa agattatagt tatggatgag ccttcatcga atttagatat taaaagcata
    91441 agtgttttgg caaagatgct aaagatatta aaagagaaag gcataagcat aattgttgca
    91501 gagcatagaa tttattattt gatggacata gttgaccgtg tatttttaat agataaagga
    91561 aagcttaaaa aaacttatac tagaagtgaa tttttaaagc tagataaaaa tgaattaaat
    91621 gctttaagtt taagagataa agaattaagt aaattaaaag ttccttattt aaaagaaggt
    91681 ggagagtatc agataaaaaa tcttagctac aaatttactg atgatgagtg tttaagctta
    91741 aaagatattt cattcaagct tgggaaaatt tatggcataa taggatccaa cggacgagga
    91801 aaatcaacgc ttttaagatg tttaataggt cttgagaaaa aatcaaaaga agaaatttat
    91861 tttaagggag agaagctatc taaaaaagaa agactcaaaa actcttcact tgttatgcaa
    91921 gatgtaaatc atcaattatt cacagatgaa gtattcaacg agcttagatt aggagtaaag
    91981 aattttgatg aagaaaaggc gaaaatcatt ttaaaagatt taggcctgga cgaatttatt
    92041 gaaaggcatc cgatgagttt atcaggaggg caaaagcaaa ggcttgcaat agcatctgtt
    92101 atgtgcaaga attctccatt tatctttttt gacgaacctt caagtggtat ggattattcc
    92161 aatatgataa aaatatctga actgattaat aagtataaaa ccatggataa aataattttt
    92221 attgtttccc atgatataga atttttaaat gaagtggcag atgaaatttt tgaattgtaa
    92281 aatagagtct gttaaacatg tctatagaac tagtaaattg tctaaaaatt taaaagatac
    92341 taacacatat tgatatttat agaaaattaa ctttaggatt tttacagtat ttataaactt
    92401 tataatatgt atttatagta ttaataattt ccatatcttt agggaaatta tttatttact
    92461 taccataatt aaagagatga gagataaata tcggcagtct tcggactgcc tttatttttt
    92521 tacttaattt aatgcagtaa atcatacgat tgaaaggaat ctgcgttata tgctataatt
    92581 aggtagttaa tctatacatt tagaaaggta aaatatagaa ttggagaatg atatgggatt
    92641 ttcatataat aaattgtaac cgcccaataa cgaagtctat tgaaaaatct ccagattagt
    92701 gaactcacgg atagttccta atctggagat ttcttatttg cacttttctt gtacaacttt
    92761 agtccacggt aaataggcct ctaaaacctc tttgtttacg agagtttcaa cgtttggaag
    92821 acattctaga agataggata gatatttctc actatttata atggattgaa ataagatatg
    92881 aacaaatcga ttaggaaagg aaaattgatt tatagaaatg ttttagcagt cgatgcgtac
    92941 tgttatagat tcaacgcact ataattgatg acgtttagct gtttccaaca aactcataat
    93001 aatagctctt gctttagctc cttcaaaact ttgagaaaat aaccaccctc gcttttttaa
    93061 actgagctta ggctaaaaga gtccactgga ctcttttact ccgtcccata accaatgatt
    93121 taatggcgca ttcagctaga ttattggaaa ggaccagatg tccgtctttc aaaatagtct
    93181 taaaggtttc tttatacttg aggctatact tgaggctgta ttcaattgcc cttcctagtt
    93241 ttgaacccga taaaactgac tgacgccggc accaagcaaa gaaatcttcc attaggggtt
    93301 ggagatgttc ttgacgtttc tgtagtcgtt catcagctgg caaagcctcc cagtttcttt
    93361 ccaaggaaaa taactgatta caataagcta aacctttagc tcctaaggat gatttattcg
    93421 cttgcttggg ggtcgcttca aaaaacttcc ttctcacatg tacccaacat ccaacaagtt
    93481 cagcttcttc cagttgacaa taagcttcta gcggttcgca gtttaccaag cttagcgtcg
    93541 ccttgctcct aaaccttgga ctgctatcgc ataggcagaa ctagaggact aaagtcctaa
    93601 gttactgccg caacatatca caatgcacat agccagaata atctcctagg aattcttgca
    93661 ctaccgaacc actccgacgc tgatcatggt ggtacagcgt gattgcttga ttctcagctt
    93721 tcccagacaa aaaggtccaa tagtaggtca gatggctatc attctctaga acccgatagg
    93781 aggtttcatc tgcatgaagt aagggctgaa tcaatagtct cgttataaag gggctttagg
    93841 aataggagct tttacaattt tatcacttgg attattctta ctgcatgttt ggcatttgta
    93901 agcgtgttgg atatgatcca ctctttttaa ttgcgcagga ataaagacca attcttgtcg
    93961 ttgaaggctc gctccaatct cttttaaatc gtcctgacaa tcagggcaaa tgctctcttc
    94021 tacttgatga tgaacttctt ctgaatcaaa ttgggcaaga atagcttgac gtttcccttt
    94081 agatttctta cgtttgtagg taatttcctc tgtttcaact gggaacatct ccatctttct
    94141 cagatggaga ctcttcctca aaaaggttga gttgtccaaa agggcaaaca cttttctcag
    94201 aggattttcc agagagcttt tgcgttagat aagccacttg ttcacacaga agggaaagtt
    94261 cattagtgag actatcaatt atagcactct gttgttgaat gattttcaat cttctcccat
    94321 agactttcct ccttatttcc taactttatt atatagtgta ttgaatctat aacagtacac
    94381 cttgactgct aaaatatttc tataaattaa tttgactttc ctgatagaga tgttcatatc
    94441 ttatttcaat tcactatact aaaaagaaag tcctcatttc aatagaaatc acgactttct
    94501 gataaattta ttttgggagt gatagaaaag cccttcataa gccaatctac ttgttcaggt
    94561 gtgagagctt tgacatcctt ttctgtactg ggccaagtca gtctgccgtt ctcaaagcgt
    94621 ttatatagta gccaaaatcc ttgaccatcc cagtaaaggg ctttaaagcg gtctttacgt
    94681 ccaccacaaa agagaaaaac ttgaccggag aaaggatcca attcaaagtg ggttttaacc
    94741 agataagcca gtgaatcgat tccttgtctc atatcagtct tcccacacac gagatagacc
    94801 tgccctaggc tagatagatg aattgtcata gagcaacacc ttatccaaaa gctgttctac
    94861 catttcgaga ttgagagatt gaaaaaaact tacttcaagc ttgccaatac gaattttaag
    94921 cagaatatca tttctctttt tagaatcaaa aggacgagat tgtggaatct ctacaggaac
    94981 aataggttgt ggcattaaaa tatcctccaa tagttttact ttactaatag tatacaggag
    95041 gaactccatg aatgatagat accttgttat gacgcgctta ctatattaga aagttggctc
    95101 tctaattaaa ttaattctca ttatatatat caaaagaccg cagtttgaaa actacggtct
    95161 aattttttgt ccaaatgtaa atcacttgga actattattc aatttattct ttttagtaaa
    95221 tgttcccgtt ttaatcctct gtaaccgttg attttacaaa gcttttaatt tttttgcgat
    95281 tactcccact caactgttgc aggtggttta cttgtaatat cgtagacgat acggttaaca
    95341 tgatccactt catttacgat acgtactgag attttttgaa gtacttccca tggaattttg
    95401 gcaaaatcag cagtcatacc atcgatagaa gtgatagcac ggattgcaat cgtgtagtca
    95461 tacgtacgac cgtcacccat aacaccgact gaacgaacgc ctgtgttaac agtgaagtat
    95521 tgccaaatat cgcggtcaag tccagcttta gcgatttctt cacgaagaat agcgtctgat
    95581 tcacgaacgg tttcaagttt ctcttcagtg atttcaccca tgacacggat agcaagtcct
    95641 ggtcctggga atggttggcg ccatacgata tggtctggca taccaagctc tgtaccaaga
    95701 gcacgaactt catccttgta aagagtattg agtggttcaa tcaattcaaa ctgcatatct
    95761 tctggaagac cacccacgtt gtggtgtgac ttgatagttt gagctgtatc cgtaccagac
    95821 tcgataacat ctgtatataa agtaccttga gcaaggaatt tcacatcttt gagcttgctt
    95881 gcttcgtcat cgaatacata gacaaactcg ttaccaatga ttttacgttt ttgttcagga
    95941 tcagaaacgc cagcaagttt gtcaaggaaa cgtttagcag cgtctgcttt gacgatattc
    96001 aaaccaaact taccaccgag catgtccata acttgatcag cttcgccttt acgaagaaga
    96061 ccgtggtcta cgaagataca gatcaattga tcgccaatcg ctttttggag aagaacccca
    96121 acgacagatg agtcaacacc acctgataga ccaagaagga cacgtttatc accgacggtt
    96181 tcacaaattt ttttgatctg catgtcaatg aaattatcca ttgaccagtc acctttagcc
    96241 ttacaaatgt taagggcaaa gttacgaagg atatcatttc cgtatacaga atgacgaact
    96301 tctgggtgga attggatacc gtaaatgtgt ttatctgggt tttcgatggc tgcgtatggg
    96361 cagtcagctg atgtacctgt acgaacaaag tcagcaggaa tctcagtaac cgcatcacca
    96421 tggctcatca aaacagtctg ttcatcaggt gttgattcaa aaagcgctga tggtgtgtga
    96481 gttagggttg attgaccgta ttcacgattt ccagcatcac ctgcaggaac aacttttcct
    96541 ccaagtttat gggtcaataa ctgcatacca taacagattc ccaaaattgg aattccgagt
    96601 tcgaagattt ctgggtcaat atcaaatgaa ccatcttcat atacagaatt tggaccacct
    96661 gatagaataa ttcctacagg attgacttca cgaacttcag cagctgaaat tttatggctt
    96721 tttagttctg aaaaaacacc aatctcacgg atacggcgtg aaatcagctg gttgtactgg
    96781 ctaccatagt ccaatacgat gattttttct acatcttgca aatcagttga aatgttgctc
    96841 atctttttcc tttctcaaaa gaaatatctt ttcccaatat tctatcacaa ataagggcga
    96901 attaccaact aaacaaggcg aagtttgact ttttctagtt tattggggta caatagagaa
    96961 aagatagaaa tgaagtgaaa aatatgctac ctgcttatat aaaaatccat gatcagataa
    97021 aaaaggatat tgacgagtac cgttgggcta ttggtgagag gcttcccagt gaaagagatt
    97081 tagctgagca gtttgcggtc agtcgcatga ccctccgcca agccgtatct ctattagtcg
    97141 aagaaggcgt cttagagcgc cgtgtaggaa gcggcacctt tgtttccagt actcgagtac
    97201 aagaaaagat gcgagggaca accagtttta ctgaaattgt caaatcccaa ggtaaagttc
    97261 cctctagcca gctcatttcc tacaaaaaaa ccattcccaa tgagcaagaa gttgccaagc
    97321 taggaatttt tccaacggac aatattatcc gaatggagcg ggtccgctat gccgaccaag
    97381 ttcccctagt ttatgaagtt gcttctattc ctgaaaaatt cattaaggac tttaaaaaag
    97441 aagaaatcac cagtcatttc ttccaaacct tgcaaaaaca tggctatcgt atcggcaaat
    97501 ctcaacagac catctatgct cgccttgcta aagaaaagat tgcccactat ttggaagttg
    97561 aaaaaggaca tgctattctt ggattgaccc aggtttccta cctagaagat ggtactgctt
    97621 ttgaatacgt aaaaagtcaa tatgtaggcg aacgctttga attttatctt gaaaataatt
    97681 agattaccac gcaaaaactc tctgtcacgg acaaagagtc ttttttattt ttctaagaat
    97741 aaatctttca aagaaatcaa agttacagca aacaatatca ttgccatacc aataaaatca
    97801 atgggataaa attgttcatt cattattaag aaggcaaaga aaaccgccga tattggctca
    97861 attgaagcca acaagcttga cttgaccggt cctatcagac tggctccttt aaggaaagct
    97921 gtataggcaa agacagtccc gataaggata atgcctgcaa acgcaaggag aaaatcaaga
    97981 ctagtcggga tatcggcctg tagaatccct gtaaaaggaa gggcgaccaa acctgctatg
    98041 accattccca caccaatgac caagctgctc ccccactttt taatcaaggc tatgggtaaa
    98101 atgatataca aagcataagt caaggcagaa aagagacccc agaacagacc agcaggtgtc
    98161 atggataact ggtccaactg cccatgtgtt gcgatcagga aggttcctcc gatggcgaat
    98221 atgatggaaa ctatctctcc cagtgtcggt gccaccctat ccttgataca gctataaatt
    98281 aaaattccga caggacaaac atactgaagc accgtcgctg ttcccgcatt ggtctcctga
    98341 atagcagaca gataggcgaa ttggttgaga aaaagaccaa tcagagcaaa aataagaaga
    98401 gacagcaaac tctttctatc ctttaaaaag accagtattt tatcctttgc agtagcataa
    98461 gccaagagca tgagaattcc accagcgatt aaaagacgca agttggtcaa gaccagagcc
    98521 gaaattccgt gtgccattaa gtattggcca ctcgttcctg acaaccccca agcaatacca
    98581 gccacaactg ttagtaaagt cccttttaaa ctatttgaca tgtctctcct tactcttctt
    98641 tgcgaatcaa gttcatcact tgattgcggt ctaatatcca ttgagctctc tcgtcctttt
    98701 cataggtacg attcgatagg aaaatagtgg cttcttgctt ctgacgattc cacatgataa
    98761 aggtacctgt atagcccgta tggtctagcc aatctccttc caaattccat gctaaagaac
    98821 gttccttgtc atccaaagga gaaaaatttt gatttaagtc tcttgcaaaa tcatctgcta
    98881 aatagtgttc taaaaagatt tgtaaatcct ttatagtcga aaataaacca gcactcccag
    98941 catgtctacc caggagacga gccttgggat catgcactat gcctgcctct acacctctaa
    99001 ctgttggaac agcaagctca actggcccaa acttggtttc cgtcattccc caaggtttcc
    99061 agacttgatc ctttaaaatc acatccaaat cttgattaaa aattctttcc aaaataaagc
    99121 ccaacagcaa aaaatggaca tccgaataaa gaaaggctgg ctgacttcgt ctgttgagat
    99181 gaaacatcgc ttcctttaat tcaggggctg ttaaaagatc acgattagga ataaaaggat
    99241 caaggtctgt tgcatgagtc aagagctggc gaatagtgat gtctggataa tcactctcag
    99301 gtaaaaaatc tattaccagt ctatcaatat ctaattgacc tatttcccac aagaaggtac
    99361 aaactgtgcc aaccccaaca accttgctga cactagctag gtcataaact agtcctgcct
    99421 cagtctgcaa gccatgctct gggtcactct ggcctaaata gaactctgtc cattgattgt
    99481 ccttaaaata cgcaaaagag gctccgggat aaatccctgc ctcgatttgt tcttctattt
    99541 ttttaataat cttggtccac ttcatacttc ttcaaaccac aattcaacat tatttctatc
    99601 tttaccaagg aagaattttt cagacttagg aataaaatat tcaatagact caaacttctg
    99661 gcgaagactt gctatgtcta attcattgac caagaacttg agcatagata agtcccaggt
    99721 aaccgtattg tccacagtca aatcctgccc ctgagctgga ataaaatcaa gggatgcccc
    99781 aatttcagat gattccaaga aactttcgat atcagttggg agatgtaatt ccatagaaat
    99841 ctcaaattta cttaaagaaa ttgatgccaa atctgtttga aattcaggct tttctcctac
    99901 ttctactaga cttgctctgt catcttccgc atgaatcaaa atcaaatcat cttctggtga
    99961 gaaaatttca aaagcgtagc cattttgacc tttatataat cgatgaatcg aatctgtttt
   100021 agataagatt ccttcaattt ctaagggatt ttccaccttg acaatcaatc tagctagttt
   100081 ttttcttccc tctaccttac gagtacgcat actgggagct tcttctaaaa ccagcttttc
   100141 aagacccgtt tggtcaccta gtgacagaaa ggccgattct tctaacaagg ccttcattcc
   100201 aagggtttca atataaaatg tttcatttaa ttttctatta ttagctttta aagtaggaat
   100261 aatccgtaca atctgattta cattcataaa ttcctccgtc actttttatt ttaaaggatt
   100321 ttagaatttt ttacaagata ttatgctcaa atttaacatt atttagctat ttagtaaaga
   100381 tagtctttca aggcttttga caaagcctga taaccagcaa tactgaggtg cagtccatca
   100441 gttgtatatt cttttttgag ttggcctgct tggtctgtca aacaatcaaa tactggcaca
   100501 aattccacct gcatataggc agatgcaagc tcttgatagg cttgattcca gttctgaatt
   100561 ttttcattcg agcggatata gactgcctgc tggtactcct ctctctcatt gacaggcaaa
   100621 atggaaagca atttaatctc tgtcaatgga taatcgcgag caacggattg aatgatagct
   100681 tcgagattat tgagagcctc attcacagga acatcctttc cgatatcatt tgtcccaatc
   100741 agaagaaaaa ttttatctac tgctccacca tatagatgag catcaaggtt ctctagtaac
   100801 agtcctgtct gatagccacg aattcctcga ttgacaatcg tctttgaagt cccaaatagc
   100861 tcctgtagag gataatactc gacaatggaa tccccaataa aaagaatgtt tggttctaca
   100921 acagaaatgt gatttaggtg acgatactta gtttgaattt tttcttgttc ctttaggagc
   100981 caattttcta ataactgtac tgccacttca ttctcctttt tctaaccagt tttccaagac
   101041 ttgataaact cctccttggc tgttggctgg tgctagagca gtcgccacag ctttggcttt
   101101 ctcatcagca ttttccatcg cataggcaat tccagccatt tcaagcattt caacatcatt
   101161 ttcactatca ccaaaagcca tgatttcttg ggatttcaag tcccagcgct tgagtaattc
   101221 ctccaagccc catgctttat gaatcccagc ttggaggata tcaatgcaac catagccact
   101281 ggatacagct cggacacggc catcaaagag agcattgatt tcttccaaaa ccgaactcaa
   101341 acgttcctca ccaacaacca tgctcatctt gagcacacca ccaaagaggt cagatgttaa
   101401 ttcatccaca aattgcatcc gttggtagaa tttttcaatc atttctggag tcataaaact
   101461 ttcaagatct gtaaaaatcg taccttcctt gacaaaatca cccttaatcc ccgttacaac
   101521 aaactggtcc tgacacgctc gacccttgaa atgagtcaaa gccttgttga caatggcgtc
   101581 atcccatgtc tgagcctgaa tcaattcatt gttttcaaaa atacgagcgc cattagcaac
   101641 aaccagaacc actcgatcca ccaagggact cagtagttgt ctcatgcggt gaatttcatt
   101701 gcccgtcgca atgacaaaac gaatgcccct ttgatccaac tgatctaaaa tcttttccaa
   101761 tcgtgggaga tcaagctgac ctctagcatc cagcaaggtc ccatccatat ctgtcgcaat
   101821 taccttaatc atcatttact ttcctctgga ttcaagctaa taccacttca atcccacatg
   101881 ttcattcatt tctttatagg ctgtatcaat tcgttcctta gtcgcttcat ctaactggtc
   101941 acgatgactg ccatcctcta taaaatcttc caaaatataa gtttggtaat gatacaaggg
   102001 atatccttct ggtgaaaagg ttccctttgg tgttcgattg acccaagtag gatgagcttt
   102061 agctgttccg atagttgttt ttccatcctt cttcttgatg gtgacatcca tgagaacacc
   102121 acgttcagtc cacttagcat tctcttcatc tcccatagat tcaattcgtt gattggaaat
   102181 gaagttcccc atttaataga caatgagctt cttatctcca tctttttcca ccgtttcaga
   102241 tggttcaaca acgtgaggat gccctccaaa gataatatcc gctccccaat caatcatctt
   102301 gtgataaaga gctttttgtt cttcagttgg ttccaatcga tactcaacac ccatctgagg
   102361 catgataatg gtgatatctg cttccttctc tgcccgttca acttcagcct ttatcttatc
   102421 ttcgtttaaa tctgaaagat aacgattata gtcttcctga gaaatatact gctcaattcc
   102481 attgaaacca taggaatagg ctaacaatgc aaccttgata gcattcactt ccttaatgac
   102541 cagcggagcc tgagcacgtg gttcgtgcgt ataaactccg attggagtga ttccagcttt
   102601 ctcaataata tcggccattg aaataactcc ctcaatttgc gaatccaaaa tatgattatg
   102661 agctaaatcc agcacatgat aacctgcctc cttaatagca tccataactt caacaggagc
   102721 attaaagaga agataacccg ctaaataatg atccttatta atggttcctt caaaatcacc
   102781 aatagctaaa tctgcttgct tgagccaagg agtcacatac tcaaaatttt catgaaagtc
   102841 ataggtaccg tcttcttttt tagctgaaaa gaaaagtcca tcgtggtaga gcaaatcccc
   102901 gtgggccata attctggcag ttttttcctc ttcctactcc tgagactttt gcttagtccc
   102961 ctcttgagaa atagtatctc gtttttgact agtcaaggga ttccttggaa gctttcaaac
   103021 aacaagacca agcccattga taaaccaact gctagcaaga gtatcgccac aaatccctta
   103081 ttgctccact tgcgataact cctaaaaagt ttaccaagcc cttcataaaa cgaaaagcta
   103141 aaccaccctg atttcgattt tgtcttcttt gtatcttcgt tctccctact ttcttatgca
   103201 agccttttct ttttattata tcacagataa gtatttcttt cacaattgaa ttgaacttcc
   103261 tatctatttt ctataaatcc taaatgccat aatgctttca attcttgtca ttttgtgata
   103321 tcatgtagag gaaatgaact aatccacagt ggcttattcc aagtatacca cttgggcttt
   103381 ggcagtagct aactgcacta aacataatat aaggagagaa aatgtctgca atagaacgta
   103441 ttacaaaagc tgctcactta attgatatga acgatattat ccgtgaaggg aatcctactc
   103501 tacgcacggt tgctgaggaa gtcactttcc ccctatctga ccaggaaatc atcctaggcg
   103561 aaaagatgat gcaattcctt aaacattccc aagatcctgt catggctgaa aaaatgggac
   103621 tccgcggtgg tgttggactg gctgctcccc agttagatat ctcaaaacgc attatcgctg
   103681 ttttggtacc taatattgtt gaagaaggcg aaactccaca ggaagcctac gatttggaag
   103741 ccattatgta caatccaaaa atcgtctctc actctgttca agatgctgct cttggcgaag
   103801 gagaaggttg cctgtctgtt gaccgtaacg tgcctggcta tgttgttcgc catgcccgcg
   103861 ttactgttga ctactttgac aaagatggag aaaaacaccg tatcaaactc aaaggctaca
   103921 actccattgt tgttcagcat gaaattgacc acattaacgg tatcatgttt tacgatcgca
   103981 tcaatgaaaa agacccattt gcagttaaag atggtttact gattcttgaa taaagaaaat
   104041 cccgttgcaa gacggggttt tgtgttataa tagaggcatg aaaacaaatg atattgtcta
   104101 tggtgtccac gctgttaccg aagccctcct tgcaaataca ggaaacaaac tctacctcca
   104161 agaagatctc cgaggtaaga atgttgagaa agtcaaggaa ctagctacag aaaagaaggt
   104221 gtccatttct tggacatcaa aaaaatctct ctctgagatg actgaaggtg ctgttcatca
   104281 aggttttgtt ctacgagtgt ctgaatttgc ctatagcgag ctagattaca tccttgcaaa
   104341 aacacgccaa gaagaaaatc cacttctatt gattctagat ggtctaaccg atccccataa
   104401 tctgggttct atcttgcgaa cagccgatgc gaccaatgtt tcaggtgtca tcattcccaa
   104461 gcaccgtact gtcggagtaa ctcctgtcgt tgccaaaaca gccacaggtg ctattgaaca
   104521 cgttccaatt gcccgagtga ccaacctcag tcaaacctta gataaactta aggatgaagg
   104581 tttctggacc tttggaacgg atatgaacgg tactccttgc cacaagtgga atacaaaagg
   104641 gaaaatcgcc ctcatcattg gaaatgaagg aaaaggtatc tctagcaaca tcaaaaaaca
   104701 ggtcgatgaa atgattacca ttccgatgaa tggacatgtt caaagcctta atgccagtgt
   104761 tgctgcggcc attctcatgt acgaagtttt ccgaaataga ctataaaaaa gtttccagtc
   104821 atctgattgg aaactttttt atgattaact atgttctgta atgaatttat aggcttcttg
   104881 accagcgata gctccatctc caaccgctgt tgttacttgg cgaaggtctt tcaagcgaac
   104941 atctccaact gcaaagatac cgtcgactgc agttttcatg tggttatttg tcacaatcca
   105001 tcctgcctga tcttggatat tcaattcttt aacaaaatcg ctaagagggt ccaaaccaac
   105061 atagataaag acaccaccga aggcttgttc tgtcacttga cctgttttca cattttcaaa
   105121 tacgactgat tctactcggt tttcaccctt gatttccctt actacagaat cccagataaa
   105181 gctgattttt tcattcgcaa aggcgcgatc ttgtaaaacc ttttgggcac gaagttggtc
   105241 acgacggtga acaatggtaa cagtcttagc aaaacgagtc aagaagaggg cttcttcaac
   105301 agctgaatct ccaccaccaa ctaccaataa atcttggtca cggaagaaag caccatcaca
   105361 cacagcacag taagaaacac cacgactgtt cagttcttct tctccaggca ctcccaaagg
   105421 acggtgttta gaaccagttg ctacgataac tgtacgtgtt tcatatgttt ggtcatcagt
   105481 catcactttc ttaaaatcac catggtcttc gacattttca acataaccat aaatgtgctc
   105541 aacaccaaga ttttcaagtg gttcaaacat cttttcagcc aattcaggtc cactaatatt
   105601 agcgtatcct gggtaatttt cgatatcaga tgtattattc atctgaccac ctggcagacc
   105661 accttcaatc aaagctactt ttagattgct tcgagcagca tacaaggccg cagtcatccc
   105721 tgcaggtcca gcaccgataa taatagtatc gtacatatag attccttctt tcttgttgta
   105781 actatcttta ttctaactct ttcttgtcaa tcacgcaagg attatgcctt gaaaacaaga
   105841 attaaactca taaccgcaaa ggataatact gggacaacca agactccaat cataatcata
   105901 tcatagagat gggcttggcg agccctggct gtcttatcaa ctcccgacat ggctctcaga
   105961 ccaatccaaa tccctaaaaa aatcagaaca aggatggtgg tcaagatcaa actctcgaaa
   106021 tataaagaaa atagttgcag tagcatgatt tctctcattt ctatcttttt taaagagtaa
   106081 actcagctag tccaactaac tgagttttcc tttatctatt atatcaaata taagtccgtt
   106141 tgtaactagc gaagaattct tttgtccgct cttctttagg ggtgtggata atctcatccg
   106201 gagttccaga ctcgatgatt ttccccttat ctaagaagag aattttatcc gcaacttggg
   106261 ctacaaagga catgtcatga ctgaccaaaa tcatggtctg acctgactta gcagcatctg
   106321 caatagactt ttctacttca ccgaccaatt ctgggtcaag ggctgaagtt ggttcgtcta
   106381 agagcaaaac atctggtttc atagcaagcg cacgcgctag ggcaacccgt tgcttctgtc
   106441 cacctgataa atggcgagga taatggtttt cacggtccga aagcccaacc ttagccaact
   106501 cttccttggc aatcttagtc gcttcttggt cagataattt cttgacaaca accaagcctt
   106561 ctttcacatt atcaagtgct gttcggcgtt caaataaatt aaactgttgg aaaaccatag
   106621 acaacttacg gcgtagggca aggatttctt cttgagtgat tttagaaaaa tcaactgaaa
   106681 aaccatcaat ctgaatagag ccactgtcag gtgtttcaag ataattgaga ctgcgaagaa
   106741 aggttgattt tccagctcct gaagaaccaa tcaaggctac gacttctcct ttttgaatat
   106801 ccaagttcag atgatccaag acagtctgtc ctgaaaagga tttgcttaaa ttcgaaatct
   106861 taatcattaa cgaaggtctc ctttcacatc tgtttgcact gtatcaggtg cagaaatagc
   106921 catttttctc tcgatgaaac gaccgaggct ttcaattccg atattgacta cccaataaac
   106981 aagggcaacg gagatgaagc gttcaaaata gcgataatca gctccaccta gaatctgagc
   107041 ttgggcaaag acttccacaa cacccgcact aaaagctaga gatgttccct tggtcaaacc
   107101 gatgagggaa ttaatcaagg ttggagtagc taccaccgct gcattaggaa taatcactcg
   107161 tcgataaact tgcgctcggg tcatacccag actgcgtgcc gcctcaatct caccaggatt
   107221 aactgagaga atggctgcac gaatggtttc actagcataa gctgcctcat taaaggcaaa
   107281 agcgacaatc gcaaaagctg cagctggaat cgcattgata ttgagaccag ttccccattg
   107341 ctgattgagg gctttcaaag ccaaagggat tccgtagtag gtcaacatga gttgcaccaa
   107401 aatcggtgtc ccttttaaga aactaacaaa gaaggcctgc aagggatata aaatcttgac
   107461 acgattgatc ttcacaatgg caaaaagaag cgccaaaacc aagccaaaaa gggcaccacc
   107521 aattgtcaac ataattgttg ttggaagttg ttggacaatt ctagggattc catcaaagac
   107581 cgaacgtagg ctaaacagct tgccatccgg aatcaattgc atcaagtttt ggtaccaatc
   107641 tgatgctaaa atcgttgtaa cattcataaa aacatcctct tctgataatg attcattcta
   107701 ccatgcttct gccgtcaatg aaattatttg ctacggtcag atacagactt tgtctaccta
   107761 ctagtttatc atactttgaa acagggaagt tatatatttt atctatcaaa gagatagata
   107821 aaaactattt cagtcccagt tcttcataag attttcgata accgatttgc ttaacagttc
   107881 cattttctac taaaatgggc cgttttaaca acataccgtc acttgctagc aactcagccg
   107941 cttcttggtt tgacaaactt cctaccttat cttttagccc taattcacgg tatttgatac
   108001 cactggtgtt gaaaaattgc ttcaattcaa atcctgaggt ttctagccaa ttcaaaatga
   108061 cttcttggct aggtgtttct tccacgatat ggacggcttt atagtccaca cctaattgat
   108121 ttaattcttg ttttgctttt ttacaagttg aacatttggg gtattcgata aattctaaca
   108181 tgtgcttctc cttctatttg tttatatctt taaaatctac gccttcatgc tccaagagcc
   108241 aagctttctt ttccactcct gcagcatagc ctgtcagacg cttgcctgct cccaacacac
   108301 gatgacaagg tactaggata gaccaaggat tgcgtcccac tgctccacca attgcttgag
   108361 cagaagccac ttgcaggtct tgagcaattt gtccataggt cactgtctga ccataaggaa
   108421 tgccctgtaa atagtcccaa actctctttt caaaattcgt tccgattggc gccaagagca
   108481 agttggataa atcctgaggc ttgcctttaa agtaatcatc taagcaagca ataactgggt
   108541 ctaaaatagg atgactaaca acttcttcta tcgtttcatc tcctagtccc ctctcaaaat
   108601 gcttctgctc ctgaacccaa attccataca aataatggtc atcagctaca agtgatagaa
   108661 taccaattgg tgaggagtag agtattttta catacttctt ttgcattatt tctttaattt
   108721 ttgataggcc aagcgttcgc catctactgg caccttacca acttgtttaa aaccaagttt
   108781 ttcaaaaata tgttgcataa ccttgttttc agcatgcgta tctgagcgaa aatcaagata
   108841 atcaaaacct tcaatcaagc cctctaagaa ggtttgagca actccttttc cctgcacatc
   108901 tgctgccaca gcaatacggt gaaagactag atactctgac tctccagctt gccagtttcc
   108961 ctcataaata gcttcatagg cctcctctgg actcttggtc acagcagcat aggctagcag
   109021 ttctccctct tccaaggcta cgtaggcttg ccctgagatg atatcatcga taataacatc
   109081 tgcatttgga tagccatttt gccactggtc actaccagca tctgctaaac attttttggc
   109141 atcctccatc acctgcatga tggcatctac ttcatttgga aaagctaaac gaatttccat
   109201 cttttttcct catttctgac tagtttctcc catcatagca taatttaagt atttctacaa
   109261 gcagttaaaa cttgactttg tgtttttgtt attttataat ctagttatca aaactatata
   109321 aaaaggagtt gaaaatgaaa actacctttt cctacccaaa atgggcagaa attccaaaca
   109381 ttgacctcta tctggaccag gttttgctct atgtcaatca ggtctgcgcc cctatctctc
   109441 ctaataaaga caagggccta acagcatcta tggtcaacaa ttatgtgaaa aatggttacc
   109501 tgacaaagcc tgacaaaaaa aaataccaac gccaacagat tgcccgtttg attgctatca
   109561 caaccctcaa gtctgtattt tctattcaag aaatagccca gacacttaat actctacaaa
   109621 ctcaagcaag ttcagaccaa ctctacgatg cttttgtgga ctacatgaac caaggaattg
   109681 acccagctaa ccctattatc caaaccagct gccaaaccgt caaactctat catcaaactc
   109741 tagacttaat cgatcatact caagaggagg taatccaatg aacactagtc ttaaactcag
   109801 caaacaactc agttttggag aggagattgc taatagcgtg acccatgctg tgggtgcagt
   109861 catcatgctt atcttgctgc ctatttcatc catctatagt tatgaagcac acggattttt
   109921 atcctctatc ggcgtttcca ttttcgtcat cagtctcttt ctcatgttcc tatcatccac
   109981 catttatcac tctatggcct atggttcgac ccacaaatat gttttgcgaa tcattgacca
   110041 ttctatgatt tacgttgcca ttgccggctc atacacgccc gttgtcttga ccttgatgaa
   110101 taactggttt ggctatctga ttattgtcat ccaatgggga acgaccatct ttggtattct
   110161 ctataaaatc tttgctaaaa aggtcaatga gaaatttagc cttgctcttt acctgattat
   110221 gggctggttg gttctggcta tcattcctgc cattatcagt caaacgacac ccgttttctg
   110281 gagtctcatg gtaactggcg gactctgtta tacagttgga gctggatttt atgccaagaa
   110341 aaaaccttat ttccacatga tttggcatct ctttatccta gctgcgtccg cacttcaata
   110401 catcgctatt gtttattaca tgtaaaaaag ttgagaaatt caatctcaac ttttttcttt
   110461 acacatattg ataaagtact ggtgcaagcg cacatcatca gtcaattctg gatgaaaaga
   110521 acttaccaac atattttttt cttgggctgc aacaatttga ttgttcactg ttgctagaat
   110581 ttctacaccc tcaccaacac tactgataat cggaccacgg ataaaggtca ttggaatctt
   110641 gccaactccc ttacattctg cttccgtgta gaaacttcct aattggcgcc cataagcatt
   110701 acgctcgacc accatatcca tagttcctag atgactctct ttctgagaag tgatttcctt
   110761 agccagcaaa attaagcccg cacaggtccc aaacactggt aagccagata gaatggcttc
   110821 tcggatggga agtagcatgt tctggtcacg taagagcttg cccatggttg tagactcacc
   110881 accaggcaaa atcaaacccg acaagtcact ctgatcttgc tgaaaatcat ctagatttct
   110941 gagttctaca ctctcgacac ctaattgatc tagcactttt gcatgttctg caaaggcccc
   111001 ttgcaaggcc aatattccga ttttcatcta ttttcctcgt tcagccatga gaatttggat
   111061 ttcattttca ttaataccaa ccatggcttc tcctaaatct tcagagattt gagctaggat
   111121 ttgaggatta cggaagttag tcacagcctt aacaatggca ctcgctcgtt taacaggatc
   111181 tcctgacttg aaaatacctg aaccgacaaa gaccccctct gcccctaatt gcatcattaa
   111241 cgcagcatct gctggtgttg caacacctcc agcagcgaaa tttacaactg gcaattttcc
   111301 atgttcatga acatattgga ccaattctac agggacttgc aaatccttgg cagcaacata
   111361 aagctcgtcc tcacgtaagt tttgaatgcg gcgaatttcc tgattcatca tacgcatatg
   111421 acgaacagct tggacgatat cccctgtccc tggttctcct ttggtacgaa tcatggaagc
   111481 accttcagcg atacgacgca aggcttcacc caaatcctta gcaccacaga caaaaggaac
   111541 ttggaattct ttcttgtcca catggaaacg gtcatcagct ggagatagaa cttcactctc
   111601 gtcgatataa tcaatttcaa tagcctctaa aatctgagct tcaacaaaat gcccgattct
   111661 gaccttagcc attactggaa tactaaccgc ttcttggatt tccttaatca tctttgggtc
   111721 gctcatgcgg gaaactcctc cagctgcacg aatatcagcc ggaattcgtt ccaaggccat
   111781 cacagctgcc gcaccagcag cttctgcgat acgagcctgt tcaggattct gcacatccat
   111841 aataacacca cccttgagca tctgtgccaa gtttttattt agttcataac gattttcagt
   111901 catttgtttt atcctcatca tttgtattgg tagctacctt ttcattttaa gtcagaacag
   111961 aatgaagcac aagataaaaa aactataatt gtatggggac agattggcta aaaattatct
   112021 gaccttaact taaggccaga tagctcattc atttctattt ttcagccgta agggcagcca
   112081 ttgtgatgta gttgtatggt ttgttgaagt gtggcaagaa gaagaggtct gtcaatgcca
   112141 atttatcaat tgtcacatgc tcttggatag caagtgagaa catgtggatt cccatgctaa
   112201 ttgcaatatc atgtgaaacc atttgggcac caagaatttc acggctatct ttgtcaaaga
   112261 caatcttaat tgctacttca tggttgtcat gtttcatgaa ttctggtttt tgaagatcgt
   112321 taaagcctgt ttcagttgcg ttgtaaccag cagctttcgc tttttcaaga gtcaaaccag
   112381 ttgaaaccat gtgaagaccg tagattgaga taccatttga accttgaaca ccgattcctt
   112441 ccaattcatg tccacaagca ttgtaggcac caacgatacc agtgcgaaca gcatttgaag
   112501 caagagcgat atagcttgta tctttacgag cattgtcata aacagtcgca cagtcaccaa
   112561 cagcgtaaac gcctgggata gatgtttctt gtttcttgtc tacaaggaag gcaccgttgc
   112621 ggaagagttc gatcttacca tctgcaaggg ctgtgtttgg acggaaacca actgcaagga
   112681 taaccatatc cacgtcaaag ctttctttgt cagtaatcaa gcgttcaact ttaccgtcac
   112741 cttcgattgc tttaacagtt tgacctagag ccaagcggat gttgtgatct tccaagttct
   112801 tcgccatcat ttgtgtgaag tctttgtcat agtaaccgtt caagacagta tcaacgatat
   112861 caacaaggac aacttctttt ccaagacgtt caaaggcttc agcaagttca acaccgatgt
   112921 aaccaccacc aacaacggcg atacggtcga ggtgttggct cttgtcagaa agtttattga
   112981 taacttcttc agcattttgg tacaatttca cgaattgtac gttttcaaga gttgctttaa
   113041 attcgcggtt tcctttaaca atttcaacac cttcgattgg tggcaagatt ggtgtagaac
   113101 ctgtagcgaa aatcaatttt tcgtatgatt ctttgtgctc ttttccttca acttccgctg
   113161 taactacttt gttatcatag tcgattgaaa gaacaggtga gttcatgtaa actttagcac
   113221 ctttagcttc caatttttct ttatcagaat agaacaagcc ttcagcaccg tcaatttgtt
   113281 caccaatcca aagagccatt ccacatccta ggaaagagat gttagagttt tggtcaaata
   113341 caacaatttc gttctcattt ccaaaattat ccaacatggt attgatacat gctgtaccag
   113401 cgtggttagc accgactaca acgattttac tcataaaaat ttcctgcctt cattctaaat
   113461 ttaccttact agtataccat ttaccgttag cgtttacaag gggggtacta ttatttcagc
   113521 attttttatc aaaaataatt ccccatttat cctgttttca agcctgatga attttatgag
   113581 catatttctt gactttttcc aaattttgtt tgtgaaaatt ctaactttat ggtattataa
   113641 taacatgaaa atgaaatgta agggcttcaa tttagatgat tatttgatat tacaacttat
   113701 tttctataag agaaaggagt tggtagcttg actcttcgtt cacattctga acggctaatg
   113761 gggactacta tcactatttc attagtggat gagcaagccg atatctttct ccaaaaatcc
   113821 tttgacttgc tcaaagaact tgaataccgc ttcaacgcca atagtcaaga atctgagttg
   113881 atggaaatca attatcaagc aggaatagcc cccgtcacgg ttcatccaga cctgtttgag
   113941 ctgatttcac ttgggttaga gcatagccta gcgctctcta gccacctcaa tatcagcatt
   114001 ggtcccttaa ttcaaacctg gcgtatcggt ttttcagatg ccaaggtcgc gcagcctcaa
   114061 gaaattgaat cggtgctgcc tctaatcaat cctcatggta tcgagttaga ttcttctact
   114121 tctactgtgt ttttaaaaca gaaaggaatg aagatcgatc taggttgttt agccaaagga
   114181 tacagtgcgg ataaggttgc ccaatttctt aggaaagagg gggtgacttc tgccttgatc
   114241 aatctgggag ggaatatcct gaccattgga aaaaatcagg caagagggga taacccatgg
   114301 caaatcggga ttcaagaccc agccaatcct aggggaaatc atttaatgac catccctgtt
   114361 gtcaataaat ctgtcgtgac ttcaggcatt tatgaacgtc acctgaccgt cgatggacaa
   114421 gattaccatc acatttttga cagtcaaaca ggatatcctg ttgaaacgga actagcgagt
   114481 ctaacaatca tctctgataa atcagtcgat ggcgaaatct ggacgactcg actctttgga
   114541 gaaagacctg cttctatcct ctggcaagtc gaaagtttgg agggcatcga agtcatcctc
   114601 atcgataaag aaggccacct aagctgttct tcaggaattc ctactctata gagacaactg
   114661 tttcaatgga attttaaaat tgtattatgt aaaaagagaa aggaaatctc atgttaaaac
   114721 ttattgctat tgttggaaca aattcaaaac gttctacaaa ccgtcaattg cttcaataca
   114781 tgcaaaaaca ctttgctgac aaagctgaaa ttgaacttgt tgaaatcaag accattcctg
   114841 tcttcaacaa accagctgac aagcaagtac ctgctgaaat attggaaatt gctgctaaaa
   114901 tcgaagaggc agatggcgtt attatcggta ctcctgagta tgatcactct attccagctg
   114961 ttttgatgag cgctcttgct tggttgtctt atggtattta cccacttttg aacaaaccaa
   115021 tcatgattac aggtgcttct tacggtacgc ttggttcatc tcgtgcccaa ttgcaacttc
   115081 gtcaaatctt gaatgctcct gaaatcaagg caaatgttct tccagatgaa ttcttgctct
   115141 cacactctct tcaagcattt aacccaagtg gcgacttggt tgaccttgat gttatcaaga
   115201 aattggatgc catctttgat gacttccgta tcttcgtgaa gattactgag aaattgcgca
   115261 atgcgcaaga attgcttcgc aaagatgctg aagactttga ctgggaaaat ttgtaagata
   115321 ggagaccaaa aagagtgaaa tttgttggac ttgttggatc aaactacgat caatcatata
   115381 accgtaagct cttggaattt atccgtcgct acttcaaact caaatttgaa ttagaagttc
   115441 ttgaaattga cgaagttcca atgtttaacc aagatgaaaa atgggatgaa agtttccaat
   115501 tacgttattt atataacaaa attactcgtg cagatggtgt tatcattgct actcctgagc
   115561 ataaccacac tatctcagct tcactcaaat ctgtacttga atggctttca tacgaagttc
   115621 atccatttga aaacaagcct gttatgattg tgggtgcatc atactatgac caaggaacat
   115681 cacgtgctca agttcacctt cgtaaaatcc ttgatgctcc aggtgttaat gcctacacgc
   115741 ttccaggtaa cgaattcctt cttggtaaag ctaaggaagc ttttgataac aacggaaata
   115801 tcaccaacga aggcactgtt aaattccttg aaacttgctt agataacttt gttaaatacg
   115861 taggagtcgt ttcgaaattg aaaaaaccaa aaccaatcga atcagaagac ttggattgtg
   115921 gaaaaccaat cgctacaacc atcacagaag ttgaccctga cgatccagaa tgggtagaaa
   115981 aagttgcagc attcactggt gctgtttctg gtgataccta tgtcaaattg gaccacggta
   116041 tcctaacagt taaccaaatt gatatgttct tgaaagctat gccatttgaa ttgacatacg
   116101 ctgacgacaa caaccaattc ctctactaca acaacgctca ccaagatcca gacactatgt
   116161 tcgctaaacg tgtaccacct caatcaggta gccgtatgtc gactgttcat ggttctcttc
   116221 caccagcacg tatgaagaac gtagagtggg ttatcggaac acttcgcaac ggaaaccaag
   116281 aatacgtccg tacgatcgtt ccaggttctc ctgcaggtgt tatcaacact cacaactacc
   116341 aagcaatgta ctatcctgat ggatcatacg ctggtatcaa tgaaatcgtc tttaacttcc
   116401 aaccatggct tgactggtac ctaaaagaga ctggtcaacg tttggtgggt ggtagcggac
   116461 catttgctcc tgctgccgga ggtcatggag acgccgatgc tacttctggc gcttctgatt
   116521 caggggatgc tggaggccac ggtggtgacg cagacgctac agccggtgca agttactaat
   116581 gatagttttt aggaaccatt atggttcctt ttttagcgaa aaaagactag caaacacaaa
   116641 ctactagtct ctttgttatc gtttcatcta tctttgttaa aagaaagaat acatatactc
   116701 aatgaaaatc aaagagcaaa ctaggaagct agccgcaggc tgtacttaag tacggcaagg
   116761 tgaagctgac gtggtttgaa tttgattttc gaagagtatt attatgaatt tggatcatca
   116821 agactacggc catgtaatcc tttttcacgt tgtacttggc gtagtttttc tggtgtaaca
   116881 tcgtttcctt cttcgtccac aattttgatt ccttcaatgt ggtgacgaac agcgcggcga
   116941 taaccttcga tgtactcctc acgtagtttg gcttgttcca ctttttcttc tggtgttaag
   117001 ccttctgttt ttttcttttt agcaagctca ttgatacgag caattttttt cggatccatt
   117061 tcttctcctc tgtaataaga taaagtccgt ttatcaaatt ttatttagtg ttaatttggt
   117121 taaaacaagc aaacttagct gctttcttgg ttagttgtga caagattgcc aaacgatttt
   117181 gacggacagc ctgatcttca gccattacca tagtattttc aaagaaagca tcaatgactg
   117241 ggctaagcgc aaagagttgt ttcaattgct gacttgcagg tcctgataaa acgagtgttt
   117301 ctactgcttc tgccaaagct ttttcttggt cattctcaaa tagtgctgaa tcaaccgtag
   117361 caaccccttc tgccttctca gccaggttaa aggcacgaga aagtgattca acagatggtt
   117421 taaaatcttc ttccttgctt acttctacga gagcacttgc tgcttccaac atatctgcca
   117481 caacaaagtt tgaacctgca agaactgctt ctttgatatc ttttggagta gagcccatca
   117541 tcttatcaac acgagccttg ataaagtcca taacctctgc tttattttca taagtcaaac
   117601 tgtcaaattt caatgcataa aggctatcaa tcagctcatc catagcaatg tgccaaccaa
   117661 aggcatccaa gatacgaacc acaccttgag ttgcacgacg aagggcataa gggtcattag
   117721 aacctgatgg aatcaatcct actgagaaga aactcaaaat cgtatccaat ttgtctgcaa
   117781 tggctagaac tgcgccgacc ttgctctctg gaagttctcc ttcagctgat gtaggcatgt
   117841 agtgttcacg aatagcagct gccaccgctg gagtttcacc agcaagaagg gtgtattttt
   117901 cacccataat tccttggagt tcgtcaaatt caccaaccat acctgtcaac aagtcaaact
   117961 tgtaaatggc tgctgcacga gcaaggtcaa ctgtttcatc cactgacaaa ctagcttttt
   118021 ctgccaaaag tacagtgatt tgacccgtac gaatcatgtg ttcacgaagg gaaccaatct
   118081 tctcatggaa ggtgacattg tttaattttt caacaagatc tgaaatcacc aatttttggt
   118141 cttcacgcca gaagaattct ccgtcttcca agcgggctac caagactttt tcatttcctt
   118201 tgatgacatt tttcaaacgc tctgcgtttc cgttacgaac agaaatgaag tttggcaaga
   118261 gttttccatc ttgatcacga acaacaaagt aacgctggtg ttccttcata gaagtcacca
   118321 agacttcttc tggaacttca aggtatttag catcaaaact tcccatgaag gcagttgggt
   118381 attcaaccaa attcaagact tcattcagca aatccgcatc aatttcgata cgtacaccat
   118441 gttttgcctc aatttccttg atttggtcaa caatcatttg ctcacgttca catggatctg
   118501 cgattacaaa ctgcttacga aggtcttctt catagctcaa tgctgactga attttggttt
   118561 ctttccccaa gaaacgatgg ccacggctca cacgacttcc cttgatatca aggaaatcca
   118621 agtcaaactc ttgctcatcc aagagaacag ttaaagtgtg aacagggcgg atgtattcaa
   118681 agctatttcc agcccagtgc atgctgacag ggaaagtcaa tgacttcaag acatctacaa
   118741 caccaggaac aatggcttca actgattggc caacttcttc cttagtgaca tagacatatt
   118801 cttcaccctt aatttcacgg aattcgatat cttcaacagt caaacctttc ccacggacaa
   118861 atccttgagc tgctttggtg aagtttccat cactatccaa ggcaattttc tttgctggtc
   118921 ccttgaaatc ttctgtcaaa tcagactgtt tgtctgataa accagtcaca cgaacagcca
   118981 aacgacgtgg tgttgagaag gtttgaatgg cttcaaaaga caggcggttt tccttgagga
   119041 aggctgccat tttttcgcct agttgttttt cacttggtgt gacaacatag gctggtaatt
   119101 cttcaagacc gagttctact aataagtttt ttgtcatgtt ttttctccga aaagtatctt
   119161 tttattttcc agtttgcctt atgtgattgg cacgcaagca accaacttcg ttgtttcatt
   119221 gctaaaattg gagccaaaag tctccaattt tgcctagtat ccttagtttc actaaggata
   119281 ccttcatcac tgcggcaact ggctcagggc tcactctgtt cgcccatttt cgtaatttgt
   119341 cactctcttt attctgcgtc ttctgctagg agtttagctc ttgtttcttc atccaaaagt
   119401 gggtagccta ggcgtttgcg ttctgcgaca aaggttttgg ctacaacacg ggccaagtta
   119461 cggatacgag cgatatagcc tgcacgctct gttacagata cggcaccacg cgcgtcaagc
   119521 agattaaagg tatgtgaaca tttgagaaca tagtcatagg cagggtgtac caagccttct
   119581 tctaatgcac gaccagcttc tttttcaaac ttatcaaagt tttcaagcaa catttcttgg
   119641 tccgaaattt caaatgaata ttttgagtgc tcatactcag gctggataaa gatttctccg
   119701 tattttacac catcagccca ctcgatatca tagacagagt ctacttcttg aatgtaagaa
   119761 gccaagcgct ccaaaccata ggtaacttcc gcagtcacag ggccagttgc caatccaccg
   119821 acttgttgga aataagtgaa ctgagtgatt tccattccgt caagccaaac ttcccaacca
   119881 agaccagctg aaccagttga tgggttttcc cagttgtcct caacaaaacg aatatcgtgc
   119941 tccaaaggat tgattcccaa tttttccaaa gactcaaggt aaagttcttg gatatttgat
   120001 ggagaaggct tcatgaccac ctggaattgg tggtgttggt agagacggtt agggttttcc
   120061 ccataacgac cgtcagcagg acgacgtgat ggctctacat aagctgcatt ccatggctca
   120121 ggtccgatag cacgaaggaa agtgtaagga ctcattgttc ccgcaccttt ttcattatca
   120181 taagcctgca taagcataca accttggtca ttccaaaatt gttgcaaagt aaggatgatt
   120241 tcctggaaag tcaatttctt agacattgtt tactcctttt tatataaatt acttgcgaca
   120301 tgagtctgcc tcgtcgatca tacgaggcaa gacgagttag tactgcgtct agctcaggca
   120361 ctctagtgct gagcgtgggg cagtccgact gtaaggaggt ttctgccact gacgcagtga
   120421 aatgtcaatt tcttagacat tgtttactcc tttagttttt atatttcttt ttcaattaat
   120481 ttctgctgaa caaaccaatc taacaaggga aaagtttttt ctgtatttgc ccataaatga
   120541 taagaatcta agaccgcttg tacactacct aaattttcta ccaacttatc tactgtcaaa
   120601 aagctgcgcc agtattcata aaaaatactt gcatagttct tatcataagt cgaagaacca
   120661 aaatcattca atgaatgcca accatacttc ttctgaaaaa gttctacgag agattgatta
   120721 caaatttttt ccgcttgaaa ttcctcttct gtcaagaaat acttgcgact aatatattca
   120781 accatcccct cttcgaacca gatataagag tcataaccat caaaatcatc taaaaaatgc
   120841 tccgaccaat gagctaactc atgtcctaca atctgtaaga ggaaattttc agataaagaa
   120901 tgatagtgac tttctattgc ttgagtttgc tgagaacact cgtagtccat caattgatac
   120961 aaatacaact ctttccaaac agctaaatca ggcgccataa ccattcgtct attatttgta
   121021 taggctggaa cagcgctttc cctaataatc tgtgtagcag cattaaaatc tgaccaaata
   121081 acggcttgcg gtaaatcaca gactgcaagt tcattcttta aaaaagattg ataatctttc
   121141 aacttttcag tatttcttac tacaaaatca cgaaatgtag ctagttgact atcgtctttt
   121201 acaagataaa ggttgtccac ggctctcctt tctttcacac aatagactga ataagcaaaa
   121261 gaaccgcgtc cgacaatcct aggttgattt aacctagggg cgtcagaaac gcggttccac
   121321 cctaatttat tacttcattg tttttgaaaa tactacagaa agcgccagct cattattttg
   121381 ccctacttgg ctcccactat cccaagctcg cttgaagaac gccataagac tttctttcct
   121441 gctgactatt atatcaaaaa ttagaataat gtacaattct ttttatgatt ttctagaaat
   121501 ccacatcatc aactcgtgga gcacccgatt gaacagcaat cgtttttaag ttttctctct
   121561 cctcatgact cagttcaatt ccaaagcaat caagattagc ttgaatacga gaggttgtga
   121621 cagattttgg aagtggtaaa aatccttctg ccaagctcca ggccaaggct atctgagcaa
   121681 tcgattttcc gtgatttgct gcgatttctt gcacttgctt gctatcaaat agttctccct
   121741 gaccaaaagg cccccaagct tccaataaaa ttcccttttc acgacagtaa gctacgactt
   121801 gatcttgata cacacctggc gccaagcgaa cttgattgac cgcaggaacg atagttgcag
   121861 tttcaagcaa ggcatccaaa tgatggggaa gaaaattgct aacgccgata gcacggattt
   121921 tcccttcttg atagaggtct tccatcgctc tccaaacttc cgcattgcga gttttccatg
   121981 cgtcattttc tctgagcggt tttgggttcg gccaatgaat caaatacaaa tccaaataat
   122041 ccaagcccag tttttctata gatttttcca aagcttgacg agtttgctca taggtttgct
   122101 gactattcca aagcttggta gttacgaaca tttcttcacg tggaactccg ctatctttga
   122161 ttgcttgacc aacactttct tcattctgat aaatcgccgc cgtatcaata tgacgataac
   122221 cagccttcaa ggcttctaac actgcatgat aggcttcttc tccatcctta gccttaaaag
   122281 ttccaaatcc caatactgga atttctactc cattatttaa ttgataggta ttcatatgct
   122341 tctccttcta ttttattcat caattatagc ataagacatt ttttaagtag tactatcttc
   122401 tgtaaaaaat aagtctgtca aatatctaac agacctattt tttcttgctt attcatcacg
   122461 actatagtac agctcatgag cttttaggcg agtattgagc atctctggta tggtcacaaa
   122521 ggtataacct tgatttttca aatactcaat gacccttggc aaggcattga ctgtcggact
   122581 gtgaatatca tgcatcaaaa cgatagagcc gttagctact tgatgctgaa tttctgtcaa
   122641 aatagatgct tcatttttac tcttccagtc cagactatcc acatcccaca tgataaagct
   122701 caaatccaag ctattgcgaa tatcatctgt aatagcacca taaggtggac gcatgagttt
   122761 agaactagaa cccagcactt tagttagcac atcctcagta tcagtaatct gctttttagc
   122821 ttcatcaaga gagagttgcg agagaatcgg atggctccaa ctatggtttc caacaacatg
   122881 accttcagat tttatcctct tcaccaagtc ctcattccca gaaacatttt tcccaagcac
   122941 aaagaaagtc gctttaatat catatttagc tagggtctct aatacctgcg gggtcgttgc
   123001 tggatttgga ccatcatcaa aggttagagc gacaactttt tgatatttct tatcaaagta
   123061 agattggtac aaggccgcat ctttttcgag taagtacgaa gattggataa catcaaagaa
   123121 agcagatact ggcaaggcta tctcttctaa attttcaagc acaggacttg gataaaggat
   123181 aatctgacta tccttgtaat caaaattcca tgcagacaag tcttggtcag agaagttttt
   123241 tacaatctgc tcactctggt cttgctctat ttttttatcc tctatgaagg gggtcaactc
   123301 ttttatcagc tgttccttag ccttactagc atctgaaaac agttggtcaa gtgtaaaagg
   123361 ttgcccatct tctgttaagt gaacctttcc tagactggtc ttttcagtct cttcaacctt
   123421 aaaagcaact aaatcataga tttgtttggt cacattacga ttaacgactc cctttaaacc
   123481 tgactcttct tgctctgtat agtagaaaac aagattgtcc ttactttcta gcttgtcctt
   123541 aacatcttga tttatcaact ccctaacaga ggaaatcact ttctcccctt ggagaggata
   123601 ataggcaatc acttcggctt gcccctgacg aaaatgctcc ttctgatttc cctcactcaa
   123661 ttgatcatct ttctcttttt tgagcgattc aatcttttgc tcaaaacttt tttgctggta
   123721 gatcttaaaa gcaataaatc cgcctaatag gcaaatagaa attgctaaaa taccaatcaa
   123781 agccaataat acatgtctcg ttttcccgtg tctgccacgt cctagtctac ttttattcat
   123841 atttatatca taacaaattt gagcaataat ttcaatgata caatttggca atccacaatt
   123901 cctctagcaa gccaaagcat cttacatcaa ctccaacatc cgtatctgta gagattatgt
   123961 agttttctat ctatggaatt tctagtagat tgaagctaga atagtagacc tatacttcta
   124021 aaacattgtt agaaatcgat ttgattgtcc tgatcgattt gtcctgttct tatttcattt
   124081 tactataaaa ctatgagaag ctaggtcatc tgagaagtaa ttactatcga caattgcgat
   124141 agcgtatact ggtgcgatgt gtttgtagct ctggtgggta tcaccttcac gttggcgaat
   124201 tttttctagg ttttgattaa cctgactgca cagataagcc cataggcgat tgatgaaaaa
   124261 attctgatga tgaacctgaa tttcgatgat aacttggatt ccattatcta actccgccaa
   124321 gacgtctata ctagtataga aatcctgcgc tgagtagggc atggaaggca agacgtgaat
   124381 gttacttccc tccaaaatcg tcacattttt tgctggcaag tccagcatat cgcggataaa
   124441 ttgacaagtg atttctggat tgctgaatat ttttttagca accaaatcat tagttgggct
   124501 gatgcccgga tgtctgagaa tcctccttct attatagcac atttttaaat ctaggtttgc
   124561 tagattctat gcttctatct atttattcgg aaaagaaagc taatagctta tttgaaattt
   124621 tctcctctct gttggatagt cccgtctatc tatgttataa tgaaagaagg atttaaaatc
   124681 ggaaaaggag tatttatgct aaaattaggt gtcatcggaa ctggcgctat cagccatcat
   124741 ttcatagaag cagcccatac cagtggagaa taccaactgg tcgcaatcta ttctagaaaa
   124801 ctagaaactg cagcaacctt tgcttctcgc tatcagaata tccaactatt cgatcaatta
   124861 gaagtcttct tcaaatcttc ttttgattta gtctatatcg ccagtccaaa ctccttacat
   124921 tttgctcagg caaaagctgc cttgtctgct ggtaaacatg ttattctcga aaagccagct
   124981 gtcactcaac cacaagaatg gtttgatttg attcaaacag ctgaaaaaaa taactgtttt
   125041 atctttgaag cagctcgtaa ttaccacgag aaagccttta ctactatcaa aaacttttta
   125101 gcagataagc aagtgttagg agcagatttc aactatgcca aatactcttc caagatgcct
   125161 gacttgttga ctggacaaac accaaatgtc ttttcaaacc gttttgctgg tggagccctc
   125221 atggatttgg ggatttatcc cctctatgct gctgttcgtc tttttggaaa agccaatgac
   125281 gcgacttacc atgctcaaca gcttgacaat agcattgacc taaatggaga tggtatcctc
   125341 ttctacccag actatcaagt tcacatcaag gctggaaaaa acatcacttc caatcttcct
   125401 tgcgagattt atacaacaga tggaaccttg actctcaaca cgattgagca tattcgctca
   125461 gctattttta ccgaccacca aggaaatcaa gtccagcttc ctatccaaca ggctcctcat
   125521 acgatgactg aggaagtcgc tgcatttgca cacatgatcc agcaaccaga tctgaatctc
   125581 taccaaactt ggctgtatga tgcaggctct gttcatgagc tactatatac catgcgccag
   125641 actgctggca ttagatttga ggcagaaaaa tgaaaaccaa actaccgact gaatggcaag
   125701 aactgagtga ccaactcggt ttccaagaat tcacccccat tcaaactcaa ctatttgagc
   125761 cccttcttgc tggagaaaac ctcctaggag tgagccaaac cggaactggt aagaccctag
   125821 cgtatctcct accaagtctt ctcagactac aaaagaaaaa agcccaacaa ctcttgattc
   125881 tagcaccaaa cacggaactt gctggacaga tttttgatgt atgtaaaacg tgggcagaag
   125941 ctatcggatt gactgctcaa ctcttccttt caggttcaag tcagaaacga caaattgaac
   126001 gccttaaaaa ggggccagaa attctgattg gaactcctgg ccgtatcttt gaactcatta
   126061 aacttaaaaa aatcaagatg atgaatgtgg aaaccatcat cctggatgaa tttgaccaat
   126121 tactagatga ttctcagatt cactttgtag aaaaaatcac tcactacgca cctcgtgacc
   126181 accaactggt ctacatgagt gccacgacca agtttgatca agaaaagatt gtgccgaata
   126241 cacgcactat tgatctctct gatcaaaaat tggacaatat ccagcatttc tacatgcagg
   126301 tagaccaacg tcatcgagtg gatatactac gaaaactggc tcatgtagag gatttccgtg
   126361 gtctagtctt cttcaatagc ctgtcagacc ttgggaatgc cgaggaaaaa ctacagtatc
   126421 gtgatatatt ggctgtttcc ctcgctagtg atgttaatgt taaatttaga aaagtcatct
   126481 tagaaaagtt taaagataac caactaaccc tgcttcttgc aactgacctt ttggctcgtg
   126541 gaattgatat cgatagccta gaatgtgtcg taaactttga tattcctaga gatagcgaaa
   126601 cctacacaca ccgtgctggc cgtactggcc gtatgggcaa ggaaggatat gttattactc
   126661 tcgtcactca tccagaagaa atcaaaaaac ttaaaaagtt tgcaagtatc cgagaaattg
   126721 tcctaaaaaa ccaagaactc tatatcaaat aaagccccat tgctctatac acatccagtg
   126781 tatggagctt ttttataagc aattcaattt tatactcatc tgctttcaaa aagcattcta
   126841 ttccatctcc gattaacgat ggactttatc acctccttct ccagtccttg tatgacatct
   126901 tggagttgat tcatgacatc ttccaaagtt cgaaaggctt tattcttaaa tccacgttta
   126961 cgaatctctt tccacacttg ttcaatgggt tcatctctgg tgtgtatgga ggaataaagg
   127021 taaaatcaat attagtcgga atctttaagg tacttgattt atgccatata gcattgtcca
   127081 taacgagtaa aaaataatca tctggataag cttgtgaaag ctcttctaaa aagacgttca
   127141 tccactcagt attacatcca ccagctatta agaaaaatga ttcgcctgta tggggcatca
   127201 acagctccat aacaatagcg aaattctcgt atatagtgac tatggacatg tggacctact
   127261 cctattggag accaacaaga tcccagttta ctgattctac cgaaaccagc ctcatcttgg
   127321 tacatcaagc gaaccttatg aaaaggtcta ctggttttaa agcgctttct tgtcttcttg
   127381 aattgagatt ttatttttag acgcgaca
//
LOCUS       DBEJHE010000003        92811 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC4 isolate 671759
            SAMN38261586-rid24793303.denovo.03, whole genome shotgun sequence.
ACCESSION   DBEJHE010000003 DBEJHE010000000
VERSION     DBEJHE010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261586
            Sequence Read Archive: SRR26833752
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 92811)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 92811)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576136.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576136.1
            Genome Coverage       :: 109x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 19:48:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,067
            CDSs (total)                      :: 2,029
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 131
            CDSs (without protein)            :: 131
            Pseudo Genes (ambiguous residues) :: 0 of 131
            Pseudo Genes (frameshifted)       :: 64 of 131
            Pseudo Genes (incomplete)         :: 59 of 131
            Pseudo Genes (internal stop)      :: 46 of 131
            Pseudo Genes (multiple problems)  :: 32 of 131
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..92811
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261586-rid24793303.denovo.03"
                     /strain="GPSC4"
                     /isolate="671759"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(199..657)
                     /locus_tag="ACL3EZ_000279"
     CDS             complement(199..657)
                     /locus_tag="ACL3EZ_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3021 domain-containing protein"
                     /protein_id="HGR0391919.1"
                     /translation="MKKQVFHDAATGVLIGLILSILFSLIYAPNTYAPLNPYSLIGQV
                     MDQHQVHGALVLLYCTLIWATIGMLFNFGNRLFSRDWSMLRATLTHFFLMLAGFVPLA
                     TLAGWFPFHWIFYLQLIIEFAIVYLIIWAILYKREAKKVDHINQLLEHRK"
     gene            complement(654..1094)
                     /locus_tag="ACL3EZ_000280"
     CDS             complement(654..1094)
                     /locus_tag="ACL3EZ_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000861967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family DNA-binding domain-containing
                     protein"
                     /protein_id="HGR0391920.1"
                     /translation="MKVELQISETYEEEKLIVQAPQETEKVQKVIEFAENLDQREKIK
                     GKIDDQVYLVEIGKIQRFYIENRKVLAETASQTYSIDLRLYQVLKLLPSNFIQISQSE
                     IINIDSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL"
     gene            1450..3399
                     /gene="mutL"
                     /locus_tag="ACL3EZ_000281"
     CDS             1450..3399
                     /gene="mutL"
                     /locus_tag="ACL3EZ_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0032300 - mismatch repair complex
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0030983 - mismatched DNA binding [Evidence
                     IEA];
                     GO_process: GO:0006298 - mismatch repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HGR0391921.1"
                     /translation="MSHIIELPEMLANQIAAGEVIERPASVVKELVENAIDAGSSQII
                     IEIEEAGLKKVQITDNGHGIAHDEVELALRRHATSKIKNQADLFRIRTLGFRGEALPS
                     IASVSVLTLLTAVDGASHGTKLVARGGEVEEVIPATSPVGTKVCVEDLFFNTPARLKY
                     MKSQQAELSHIIDIVNRLGLAHPEISFSLISDGKEMTRTAGTGQLRQAIAGIYGLVSA
                     KKMIEIENSDLDFEISGFVSLPELTRANRNYISLFINGRYIKNFLLNRAILDGFGSKL
                     MVGRFPLAVIHIHIDPYLADVNVHPTKQEVRISKEKELMTLVSEAIANSLKEQTLIPD
                     ALENLAKSTVRNREKVEQTILPLKENTLYYEKTEPSRPSQTEVADYQVELTDEGQDLT
                     LFAKETLDRLTKPAKLHFAERKPANYDQLDHPELDLASIDKAYDKLEREEASSFPELE
                     FFGQMHGTYLFAQGRDGLYIIDQHAAQERVKYEEYRESIGNVDQSQQQLLVPYIFEFP
                     ADDALRLKERMPLLEEVGVFLAEYGENQFILREHPIWMAEEEIESGIYEMCDMLLLTK
                     EVSIKKYRAELAIMMSCKRSIKANHRIDDHSARQLLYQLSQCDNPYNCPHGRPVLVHF
                     TKSDMEKMFRRIQENHTSLRELGKY"
     gene            complement(3724..4191)
                     /gene="ribE"
                     /locus_tag="ACL3EZ_000282"
     CDS             complement(3724..4191)
                     /gene="ribE"
                     /locus_tag="ACL3EZ_000282"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009349 - riboflavin synthase complex
                     [Evidence IEA];
                     GO_function: GO:0000906 - 6,7-dimethyl-8-ribityllumazine
                     synthase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HGR0391922.1"
                     /translation="MNTYEGNLVANNIKIGIVVARFNEFITSKLLSGALDNLKRENVN
                     EKDIEVAWVPGAFEIPLIASKMAKSKKYDAIICLGAVIRGNTSHYDYVCSEVSKGIAQ
                     ISLNSEIPVMFGVLTTDTIEQAIERAGTKAGNKGSECAQGAIEMVNLIRTLDA"
     gene            complement(4192..5397)
                     /locus_tag="ACL3EZ_000283"
     CDS             complement(4192..5397)
                     /locus_tag="ACL3EZ_000283"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003935 - GTP cyclohydrolase II activity
                     [Evidence IEA];
                     GO_function: GO:0008686 -
                     3,4-dihydroxy-2-butanone-4-phosphate synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HGR0391923.1"
                     /translation="MEYRKIQETLEALQKGRLVLVIDDKDRENEGDLICSAQAATTEN
                     VNFMATYAKGLICMPMSESLANQLMLSPMVENNTDNHKTAFTVSIDYKETTTGISAEE
                     RGLTARMCVAEDITPSDFRRPGHMFPLIAKKGGVLERNGHTEATVDLLKLAGLKECGL
                     CCEIMNHDGKMMRTDDLIQFSKKHNIPLITIKELQEYRKVYDQLIERVSTVNMPTRYG
                     NFKAISYIDKLNGEHHLALIMGNIEDEANVLCRVHSECLTGDVLGSLRCDCGQQFDKA
                     MKMIVENGSGVLLYLRQEGRGIGLINKLKAYHLQDQGMDTLDANLALGFEGDLREYHI
                     GAQMLKDLGLQSLHLLTNNPDKVEQLEKYGITISSRISIEIEANPYDSFYLETKKNRM
                     GHILNMEEK"
     gene            complement(5417..6052)
                     /gene="ribE"
                     /locus_tag="ACL3EZ_000284"
     CDS             complement(5417..6052)
                     /gene="ribE"
                     /locus_tag="ACL3EZ_000284"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004746 - riboflavin synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HGR0391924.1"
                     /translation="MFTGIIEEIGKVERIQKDSRNCKLSIKASKILTDIHLGDSIAVN
                     GICLTVTHFNHQSFTVDVMNETWSRTALTLLKHGSEVNLERALSINGRLGGHVVTGHI
                     DGTGKISSIKKDDNAVWYQINTQKEILDLIVEKGSITIDGISLTVAKVSKVNFSVSVI
                     PHTLKQTILKSKQVGSTVNLENDILGKYVQKLMDNSPKSEISKELLYQNGF"
     gene            complement(6037..7137)
                     /gene="ribD"
                     /locus_tag="ACL3EZ_000285"
     CDS             complement(6037..7137)
                     /gene="ribD"
                     /locus_tag="ACL3EZ_000285"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008703 -
                     5-amino-6-(5-phosphoribosylamino)uracil reductase activity
                     [Evidence IEA];
                     GO_function: GO:0008835 -
                     diaminohydroxyphosphoribosylaminopyrimidine deaminase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HGR0391925.1"
                     /translation="MSDSKYMKLAIKLAQKGAGYVNPNPMVGAVIVKDNHIIGQGYHE
                     FFGGPHAERNALKNCRESPVGATLYVTLEPCCHFGKTPPCIDAIIDSGITRVVIGSLD
                     CNPIVSGKGVKILEENNLQVTVGILENECLNLIKSFRKYITQHVPYVFMKYAMSMDGK
                     IATKTNQSKWITEEEARKHVHQLRHHVSAIMVGVNTVIQDDPLLTCRLEEGKNPIRII
                     CDTHLRTPLTSKIVKTANDIKTYIATSSEDKNKMKLYQNHGCEILSIKKKGNHIDLSS
                     LMQHLGNMQIDSLVLEGGSLMNWSALEQQIVDELKIYIAPKIFGGSAKFPVGGEGISL
                     PNDAIRLKPYAFSQIGNDYLIESEVIYPCSQE"
     regulatory      complement(7272..7386)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            7543..8136
                     /gene="ruvA"
                     /locus_tag="ACL3EZ_000286"
     CDS             7543..8136
                     /gene="ruvA"
                     /locus_tag="ACL3EZ_000286"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000271492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009379 - Holliday junction helicase
                     complex [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0009378 - four-way junction helicase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HGR0391926.1"
                     /translation="MYAYLKGIITKITAKYIVLETNGIGYILHVANPYAYSGQVNQED
                     QIYVHQVVREDAHLLYGFRSEDEKKLFLSLISVSGIGPVSALAIIAADDNAGLVQAIE
                     TKNITYLTKFPKIGKKTAQQMVLDLEGKVVVAGDDLPAKVAVQASAENQELEEAMEAM
                     LALGYKATELKKIKKFFEGTTDTAENYIKSALKMLVK"
     gene            8146..8709
                     /locus_tag="ACL3EZ_000287"
     CDS             8146..8709
                     /locus_tag="ACL3EZ_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HGR0391927.1"
                     /translation="MTKRCSWVKMTNPLYIAYHDEEWGQPLHDDQALFELLCMETYQA
                     GLSWETVLNKRQAFREAFHSYQIHSVAEMTETELEAMLENPAIIRNRAKLFATRANAQ
                     VLLQLQAEYGSFDAYLWSFVEGKIVVNDVPDYRQAPAKTPLSEKLAKDLKKRGFKFTG
                     PVAVLSFLQAAGLVDDHENDCEWKGLK"
     gene            8706..9383
                     /locus_tag="ACL3EZ_000288"
     CDS             8706..9383
                     /locus_tag="ACL3EZ_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000987430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="HGR0391928.1"
                     /translation="MMSNKNKGILIFAILYTVLFVFDGVKLLASLMPSVIANYLVYVV
                     LALYGSFLFKDRLIQQWKEIRKTKRKFFFGVLTGWLFLILMTVVFEFVSEMLKQFVGL
                     DGQGLNQSNIQSTFQEQPLLIAVFACVIGPLVEELFFRQVLLHYLQERLPGLLSIILV
                     GLVFALTHMHSLALSEWIGAVGYLGGGLAFSIIYVKEKENIYYPLLVHMLSNSLSLII
                     LAISIVK"
     gene            complement(9538..10569)
                     /locus_tag="ACL3EZ_000289"
     CDS             complement(9538..10569)
                     /locus_tag="ACL3EZ_000289"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000255096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S66 peptidase family protein"
                     /protein_id="HGR0391929.1"
                     /translation="MVSTIGIVSLSSGIIGEDFVKHEVDLGIQRLKDLGLNPIFLSHS
                     LKGLDFIKDHPEARAEDLIHAFSDDSIDMILCAIGGDDTYRLLPYLFENDQLQKVIKQ
                     KIFLGFSDTTMNHLMLHKLGIKTFYGQSFLADICELDKEMLAYSLHYFKELIKTGRIS
                     EIRPSDVWYEERTDFSPTALGTPRVSHTNTGFDLLQGSAQFEGKILGGCLESLYDIFD
                     NSRYADSTELCQKYKLFPDLSDWEGKILLLETSEEKPKPEDFKKMLLTLKDTGIFAVI
                     NGLLVGKPMDETFHDDYKEALLDIIDSNIPIVYNLNVGHATPRAIVPFGVHAHVDAQE
                     QVIRFDYNK"
     gene            complement(10824..11507)
                     /locus_tag="ACL3EZ_000290"
     CDS             complement(10824..11507)
                     /locus_tag="ACL3EZ_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HGR0391930.1"
                     /translation="MSQIDLQKLTKKNQEFVHIATQQFIKDGKTDAEIQTIFEEVIPQ
                     ILEEQSKGTTARSLYGAPTHWAHSFTVKEQYEKEHPKENDDPKLMIMDSALFITSLFA
                     LVSALTTFFAADQAFGYGLITLLLVGLVGGFAFYLMYYFVYQYYGSDMDRSQRPPFWK
                     SVLVILASMFLWLLVFFATSFLPASLNPVLDPLPLAIIGAALLALRFYLKKRLNIRSA
                     SAGPTRYQE"
     gene            complement(11519..12463)
                     /locus_tag="ACL3EZ_000291"
     CDS             complement(11519..12463)
                     /locus_tag="ACL3EZ_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HGR0391931.1"
                     /translation="MKQVFLSTTTEFKEIDTLEPGTWINLVNPTQNESLEIANTFDID
                     IADLRAPLDAEEMSRITIEDEYTLIIVDVPVTEERNNRTYYVTIPLGIIITEETIITT
                     CLEPLPVLDVFINRRLRNFYTFMRSRFIFQILYRNAELYLTALRSIDRKSEQIESQLH
                     QSTRNEELIELMELEKTIVYFKASLKTNERVIKKLTSSTSNIKKYLEDEDLLEDTLIE
                     TQQAIEMADIYGNVLHSMTETFASIISNNQNNIMKTLALVTIVMSIPTMVFSAYGMNF
                     KDNEIPLNGEPNAFWLIVFIAFAMSVSLTLYLIHKKWF"
     gene            12595..15426
                     /gene="uvrA"
                     /locus_tag="ACL3EZ_000292"
     CDS             12595..15426
                     /gene="uvrA"
                     /locus_tag="ACL3EZ_000292"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HGR0391932.1"
                     /translation="MQDKIVIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFD
                     TLYAEGQRRYVESLSAYARQFLGNMEKPDVDAIDGLSPAISIDQKTTSKNPRSTVGTT
                     TEINDYLRLLYARVGTPYCINGHGAINASSVEQIVDKVLELPERQRLQILAPVIRKKK
                     GQHKSVIEKVQKDGYVRVRVDGEVYDVTEVPELSKSKQHNIDVVVDRIVIKEGIRSRL
                     FDSIEAALRIAEGYVIIDTMDDSELLFSEHYACPVCGFTVPELEPRLFSFNAPFGSCS
                     ECDGLGIKLEVDTDLVVPDASKTLHEGALAPWNPISSNYYPNMLEQAMKVFGVAMDKP
                     FEDLSEEDKNLILYGSDGKEFHFHYENEFGGVRDIDIPFEGVINNIKRRYHETNSDYT
                     RTQMRLYMNELTCGTCQGYRLNDQALSVRVGGQQGPHIGEISDLSIADHLDLVSQLTL
                     SENEAIIARPILKEIKDRLTFLNNVGLNYLTLSRSAGTLSGGESQRIRLATQIGSNLS
                     GVLYILDEPSIGLHQRDNDRLIASLKKMRDLGNTLIVVEHDEDTMREADYLIDVGPGA
                     GVFGGEIVAAGTPKQVARNSKSITGQYLSGKRVIPVPEERRVGNGRFIEVTGARENNL
                     QNVTARFPLGKFIAVTGVSGSGKSTLINSILKKAIAQKLNRNSDKPGKFKTITGIEHV
                     DRLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNEAKIRGYKKGRFSFNVKGGRC
                     EACSGDGIIKIEMHFLPDVYVACEVCHGTRYNSETLEVHYKEKNISQVLDMTVNDAVE
                     FFQHIPKIQRKLQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSFYIL
                     DEPTTGLHTEDIARLLKVLARFVDAGNTVLVIEHNLDVIKTADHIIDLGPEGGVGGGT
                     IIVTGTPEEVAANEASYTGHYLKGKLHHE"
     gene            15419..16480
                     /locus_tag="ACL3EZ_000293"
     CDS             15419..16480
                     /locus_tag="ACL3EZ_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M24 family metallopeptidase"
                     /protein_id="HGR0391933.1"
                     /translation="MNKRVQAFLAKMQEKELDGIIINNLKNVYYLTGFWGSNGTVFIS
                     RDRQVLVTDSRYIIAAKQETSGFEIVADRDELAVIAGIVKDMNLTRIGFEDEISVSYY
                     HRMQAAFAGLNLLPQTQFVEGLRMIKDEAEIAAIRKACSISDQAFRDALDFIKPGKTE
                     IEIANFLDFRMRELGASGLSFDTILASGINSSKPHAHPMHKPVELGEAITMDFGCLYD
                     HYVSDMTRTIYLGHVSDEQAEIYNTVLKANQALIDQAKAGLGFRDFDKIPRDIIIEAG
                     YGDYFTHGIGHGIGLDIHEEPYFSQTSTETIKTGMALTDEPGIYIEGKYGVRIEDDIL
                     ITETGCELLTLAPKELIVI"
     gene            16612..17010
                     /gene="spx"
                     /locus_tag="ACL3EZ_000294"
     CDS             16612..17010
                     /gene="spx"
                     /locus_tag="ACL3EZ_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HGR0391934.1"
                     /translation="MIKIYTVSSCTSCKKAKTWLNAHQLSYKEQNLGKEGITREELLD
                     ILTKTDNGIASIVSSKNRYAKALGVDIEDLSVNEVLNLIMETPRILKSPILVDEKRLQ
                     VGYKEDDIRAFLPRSVRNVENAEARLRAAL"
     gene            17076..17645
                     /locus_tag="ACL3EZ_000295"
     CDS             17076..17645
                     /locus_tag="ACL3EZ_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP0191 family lipoprotein"
                     /protein_id="HGR0391935.1"
                     /translation="MKKIVLVSLAFLFVLVGCGQKKETGPATKTEKDTLQSALPVIEN
                     AEKNTVVTKTLVLPKSDDGSQQTQTITYKDKTFLSLAIQQKRPVSDELKTYIDQHGVE
                     ETQKALLEAEEKDKSIIEARKLAGFKLETKLLSATELQTTTSFDFQVLDVKKASQLEH
                     LKNIGLENLLKNEPSKYISDRLANGATEQ"
     gene            17732..17998
                     /locus_tag="ACL3EZ_000296"
     CDS             17732..17998
                     /locus_tag="ACL3EZ_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HGR0391936.1"
                     /translation="MGFTEETVRFKLDDSNKKEISETLTDVYASLNDKGYNPINQIVG
                     YVLSGDPAYVPRYNNARNQIRKYERDEIVEELVRYYLKGQGVDL"
     gene            18002..18421
                     /gene="ruvX"
                     /locus_tag="ACL3EZ_000297"
     CDS             18002..18421
                     /gene="ruvX"
                     /locus_tag="ACL3EZ_000297"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003090938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HGR0391937.1"
                     /translation="MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIQINEEQGQFGFDR
                     VKELVDTYKVERFVVGLPKNMNNTSGPRVEASQAYGAKLEEFFGLPVDYQDERLTTVA
                     AERMLIEQADISRNKRKKVIDKLAAQLILQNYLDRKF"
     gene            18437..18742
                     /locus_tag="ACL3EZ_000298"
     CDS             18437..18742
                     /locus_tag="ACL3EZ_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HGR0391938.1"
                     /translation="MSHDHNHDHEERELITLVDEQGNETLFEILLTIDGKEEFGKNYV
                     LLVPVNAEEDEDGQVEIQAYSFIENEDGTEGELQPIPEDSEDEWNMIEEVFNSFMEE"
     gene            19000..20250
                     /locus_tag="ACL3EZ_000299"
     CDS             19000..20250
                     /locus_tag="ACL3EZ_000299"
                     /EC_number="6.3.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004326 - tetrahydrofolylpolyglutamate
                     synthase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008841 - dihydrofolate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="folylpolyglutamate synthase/dihydrofolate
                     synthase family protein"
                     /protein_id="HGR0391939.1"
                     /translation="MFEVEEWLHSRIGLNFRSGLGRMQQAVDLLGNPEQSYPIIHVTG
                     TNGKGSTIAFMRELFMGHGKKVATFTSPHIVSINDRICINGQPIADADFIRLTDQVKE
                     MEKTLLQTPAQLSFFELLTLVAFLYFREQEVDLVLLEVGIGGLLDTTNVVTGELAVIT
                     SIGLDHQETLGDSLEAIAEQKAGIFKAGKKAVIAKLPPEARLVCQKKAESLAVDLYQA
                     GQDFSVLNGDFSSSLLNLSQLNIGLEGAYQQENAALALQTFLLFMGERKEAIDEQAVR
                     KALEQTHWAGRLERIRPQIYLDGAHNLPALTRLVEFIKEKEQEGYRPQILFGSLKRKD
                     YQGMLGYLTENLPQVELKMTGFDYQGSLDETDVTGYHVIPSYREFISSFEERADAQDL
                     LFVTGSLYFISEVRGYLLDREQIN"
     gene            20334..20789
                     /locus_tag="ACL3EZ_000300"
     CDS             20334..20789
                     /locus_tag="ACL3EZ_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0198 family lipoprotein"
                     /protein_id="HGR0391940.1"
                     /translation="MKLKRFTLSLASLASFSLLVACSQRAQQVQQPVAQQVQQPAQQN
                     TNTANAGGNQNQAAPVQNQPVAQPTDIDGTYTGQDDGDRITLVVTGTTGTWTELESDG
                     DQKVKQVTFDSANQRMIIGDDVKIYTVNGNQIVVDDMDRDPSDQIVLTK"
     gene            20935..22467
                     /gene="cls"
                     /locus_tag="ACL3EZ_000301"
     CDS             20935..22467
                     /gene="cls"
                     /locus_tag="ACL3EZ_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000877342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008808 - cardiolipin synthase activity
                     [Evidence IEA];
                     GO_function: GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA];
                     GO_process: GO:0032049 - cardiolipin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HGR0391941.1"
                     /translation="MKYRKFQLLMSKYGFSLSIMLLELCLVFGLFLYLGRMAPILWIT
                     VLILLSIITIISIVNRNTTPENKVTWLLVAFVPVFGPLLYLMFGERRLSKKEIKQLKK
                     LGSMHFQEANSQLLKEKLKESDKAAYGVIKSLLSMDTNADIYDQTASTFFPNGEAMWK
                     KMVEDLKKAEKFIFLEYYIIEEGLMWNRILDILEQKVAQGVEVKMLYDDIGCMATLTG
                     DYAHRLRQLGIEAHKFNKVIPRLTVAYNNRDHRKILIVDGQIAYTGGVNLADEYINHV
                     ERFGYWKDSGIRLDGLAVKALTRLFLTTWYINRGEISDFDQYHLENHSIPSDGLTIPY
                     GSGPKPIFRAQVGKKVYQSLINQATESVYITTPYLIIDYDLTETIKNAAMRGVDVRII
                     TPYIPDKKFIQLVTRGAYPDLLSAGVRIYEYSPGFIHSKQMLVDEDFAVVGTINLDYR
                     SLVHHYENAVLLYKTPSIREIARDFRNIFADSQEVYPHSIKTSWYQKLVKEIAQLFAP
                     IL"
     gene            22545..22688
                     /locus_tag="ACL3EZ_000302"
     CDS             22545..22688
                     /locus_tag="ACL3EZ_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000956126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0391942.1"
                     /translation="MLTKEEVNDMIEFKQTHLHRFREIETFVKLCKKSLKQPSQADNP
                     RTF"
     gene            22725..24263
                     /locus_tag="ACL3EZ_000303"
     CDS             22725..24263
                     /locus_tag="ACL3EZ_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HGR0391943.1"
                     /translation="MSVYGRVEEVHKENREPLEYQIEQESHHRESSRLPLVKILLWST
                     LVTGITLGVPLLLDLMSAQEVQDFYAGWGLHQTGKIYSDYYGSQGLLYYLLTYVSQGG
                     FFFAIFEWLALVAGGFFLFRSADTLTEQGDQAGHLVTIFYMLVTGLAFGGGYATLLAL
                     PFLFAAFSLVAAYLSNPSHDKGFVRIGLALAGGFFFAPLSSLLFIAVVSLGLLVFNLG
                     HRRFAHGFYQFLAVALGFSLVFYPTAYYSAATGSFGDAISGIRYPIDSIRFDFTSKIL
                     ENMFFYGLLSLGLGFVVCIFLGLFQSKPFKLYVISVPASLVVILGLILLFFSQEPLHA
                     SYLMVVFPVFLLLLVTNIKSQQRGRSARRSRRETPVSLWSRFFKGNLYLLVFGFVYLL
                     SVPFLMKFVLYPVPYQERNRLADLVKEETNTEDAIYAWDDTATLYRKSERLSPSAILS
                     PLHYTATEENRNKLLNDLKEKQPKVIVVNDKVVVWSEVETLLKENYQQVKTDYSEFKV
                     YKIK"
     gene            24383..26590
                     /gene="nrdD"
                     /locus_tag="ACL3EZ_000304"
     CDS             24383..26590
                     /gene="nrdD"
                     /locus_tag="ACL3EZ_000304"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004239081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008998 - ribonucleoside-triphosphate
                     reductase (thioredoxin) activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HGR0391944.1"
                     /translation="MIALEEKITILPTLFVEKRDGRRVVFDVDKIDKALHKAADKVMD
                     VTPLVEKRLNDLTERIITEIHSRFPQGIKIYEIQNIVEHELLEAKEYALAEEYITYRT
                     QRDFERSKATDINFSIHKLLNKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLQML
                     PKHVANAHQKGDIHYHDLDYSPYTPMTNCCLIDFKGMLENGFKIGNAEVESPKSIQTA
                     TAQISQIIANVASSQYGGCSADRIDEILAPYAEKNYQKHLKDAEEWVLPEKREDYAWK
                     KTQKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSRFEREIQKAILNIRTKGLG
                     SEHRTAIFPKLIFTLKRGLNLEEGTPNYDIKQLALECATKRMYPDVLSYDKIVDLTGS
                     FKVPMGCRSFLQGWKDENGVEVNSGRMNLGVVTVNLPRIALESEGDMNKFWEIFNERM
                     NIAEDALVYRVERTKEATPANAPILYQYGAFGHRLGKEESVDQLFKNRRATVSLGYIG
                     LYEVATVFFGNSWESNPDAKEFTLDIIHDMKRRVEEWSDQYGYHFSIYSTPSESLTDR
                     FCRLDIDKFGSIPDITDKEYYTNSFHYDVRKNPTPFEKLDFEKVYPEAGASGGFIHYC
                     EYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDRCYKCDFEGDFEPTERGFACPNCGN
                     SDPKTVDVVKRTCGYLGNPQARPMVNGRHKEIAARVKHMNGSTIKIAGHQVTN"
     gene            26602..26742
                     /locus_tag="ACL3EZ_000305"
     CDS             26602..26742
                     /locus_tag="ACL3EZ_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0391945.1"
                     /translation="MGKYQLDDKGRAQVTRYHEKHSKGGAGKKERLLSFREQFLNKNK
                     KK"
     gene            26786..27292
                     /locus_tag="ACL3EZ_000306"
     CDS             26786..27292
                     /locus_tag="ACL3EZ_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000423398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR0391946.1"
                     /translation="MELRRPRLADKKAVLDMMTEFEKSQSAHDGGFWDTENFVYEEWL
                     ESNQEQEMGINLPEGWVPAIQLVAFSEKGQAVGFLNLRLRLSNFLLEEGGHIGYSIRP
                     SERGKGYAKETLRQGLQVAKEKNIKKALVTCSVNNPASRAVILANGGIFEDAHNGVER
                     YWIEVANE"
     gene            27285..27875
                     /gene="nrdG"
                     /locus_tag="ACL3EZ_000307"
     CDS             27285..27875
                     /gene="nrdG"
                     /locus_tag="ACL3EZ_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001064213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043365 -
                     [formate-C-acetyltransferase]-activating enzyme activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HGR0391947.1"
                     /translation="MNNPKPQEWKSEELSQGRIIDYKAFNFVDGEGVRNSLYVSGCMF
                     HCEGCYNVATWSFNAGIPYTAELEEQIMADLAQPYVQGLTLLGGEPFLNTGILLPLVK
                     RIRKELPDKDIWSWTGYTWEEMMLETPDKLEFLSLIDILVDGRYDRTKRNLMLQFRGS
                     SNQRIIDVQKSLKSGQVVIWDKLNDGKESYEQVKRE"
     gene            27872..28489
                     /locus_tag="ACL3EZ_000308"
     CDS             27872..28489
                     /locus_tag="ACL3EZ_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HGR0391948.1"
                     /translation="MKKKDLVDQLVSEIETGKVRTLGIYGHGASGKSTFAQELYQALD
                     STTVNLLETDPYITSGRYLVVPKDAPNQKVTASLPVAHELESLQRDILALQAGMDVLT
                     IEEPWKASEVLSGAKPILIVEGMSVGFLPKELFEKTICFYTDEETELKRRLARDTTVR
                     NRDASFILASHQMRREQYLRYYKETESKADILVDQSEDKFDVKRT"
     gene            28755..29063
                     /gene="rpsJ"
                     /locus_tag="ACL3EZ_000309"
     CDS             28755..29063
                     /gene="rpsJ"
                     /locus_tag="ACL3EZ_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HGR0391949.1"
                     /translation="MANKKIRIRLKAYEHRTLDTAAAKIVESATRTGAQVAGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTQKTVDALMKLDLPSGVNVEIKL
                     "
     gene            29280..29906
                     /gene="rplC"
                     /locus_tag="ACL3EZ_000310"
     CDS             29280..29906
                     /gene="rplC"
                     /locus_tag="ACL3EZ_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HGR0391950.1"
                     /translation="MTKGILGKKVGMTQIFTEAGELIPVTVIEATPNVVLQVKTVETD
                     GYNAIQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNVEGLEVGAEITVETFAA
                     GDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKGKNLAG
                     RMGGDRVTIQNLEVVQVVPEKNVILIKGNVPGAKKSLITIKSAVKAGK"
     gene            29931..30554
                     /gene="rplD"
                     /locus_tag="ACL3EZ_000311"
     CDS             29931..30554
                     /gene="rplD"
                     /locus_tag="ACL3EZ_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HGR0391951.1"
                     /translation="MANVTLFDQTGKEAGQVVLNDAVFGIEPNESVVFDVIISQRASL
                     RQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLP
                     QKVRRLALKSVYSEKVAENKFVAVDALSFTAPKTAEFAKVLAALSIDSKVLVILEEGN
                     EFAALSARNLPNVKVATATTASVLDIANSDKLLVTQAAISKIEEVLA"
     gene            30554..30850
                     /locus_tag="ACL3EZ_000312"
     CDS             30554..30850
                     /locus_tag="ACL3EZ_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HGR0391952.1"
                     /translation="MNLYDVIKKPVITESSMAQLEAGKYVFEVDTRAHKLLIKQAVEA
                     AFEGVKVANVNTINVKPKAKRVGRYTGFTNKTKKAIITLTADSKAIELFAAEAE"
     gene            30868..31701
                     /gene="rplB"
                     /locus_tag="ACL3EZ_000313"
     CDS             30868..31701
                     /gene="rplB"
                     /locus_tag="ACL3EZ_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HGR0391953.1"
                     /translation="MGIRVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVALKSKAGRN
                     NNGRITVRHQGGGHKRFYRLVDFKRNKDNVEAVVKTIEYDPNRSANIALVHYTDGVKA
                     YIIAPKGLEVGQRIVSGPEADIKVGNALPLANIPVGTLIHNIELKPGRGGELVRAAGA
                     SAQVLGSEGKYVLVRLQSGEVRMILGTCRATVGVVGNEQHGLVNLGKAGRSRWKGIRP
                     TVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSDKLIVRRRNE
                     K"
     gene            31805..32086
                     /gene="rpsS"
                     /locus_tag="ACL3EZ_000314"
     CDS             31805..32086
                     /gene="rpsS"
                     /locus_tag="ACL3EZ_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HGR0391954.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSF
                     IGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRRK"
     gene            32098..32442
                     /gene="rplV"
                     /locus_tag="ACL3EZ_000315"
     CDS             32098..32442
                     /gene="rplV"
                     /locus_tag="ACL3EZ_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HGR0391955.1"
                     /translation="MAEITSAKAMARTVRVSPRKSRLVLDNIRGKSVADAIAILTFTP
                     NKAAEIILKVLNSAVANAENNFGLDKANLVVSEAFANEGPTMKRFRPRAKGSASPINK
                     RTAHITVAVAEK"
     gene            32455..33108
                     /gene="rpsC"
                     /locus_tag="ACL3EZ_000316"
     CDS             32455..33108
                     /gene="rpsC"
                     /locus_tag="ACL3EZ_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HGR0391956.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFVQK
                     ELADAAVSTIEIERAVNKVNVSLHTAKPGMVIGKGGANVDALRAKLNKLTGKQVHINI
                     IEIKQPDLDAHLVGEGIARQLEQRVAFRRAQKQAIQRAMRAGAKGIKTQVSGRLNGAD
                     IARAEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK"
     gene            33112..33525
                     /gene="rplP"
                     /locus_tag="ACL3EZ_000317"
     CDS             33112..33525
                     /gene="rplP"
                     /locus_tag="ACL3EZ_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HGR0391957.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQATTSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKV
                     MFEIAGVSEEIAREALRLASHKLPVKCKFVKREAE"
     gene            33535..33741
                     /gene="rpmC"
                     /locus_tag="ACL3EZ_000318"
     CDS             33535..33741
                     /gene="rpmC"
                     /locus_tag="ACL3EZ_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HGR0391958.1"
                     /translation="MKLNEVKEFVKELRGLSQEELAKRENELKKELFELRFQAATGQL
                     EQTARLKEVKKQIARIKTVQSEAK"
     gene            33766..34026
                     /gene="rpsQ"
                     /locus_tag="ACL3EZ_000319"
     CDS             33766..34026
                     /gene="rpsQ"
                     /locus_tag="ACL3EZ_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HGR0391959.1"
                     /translation="MERNNRKVLVGRVVSDKMDKTITVVVETKRNHPVYGKRINYSKK
                     YKAHDENNVAKEGDIVRIMETRPLSATKRFRLVEVVEEAVII"
     gene            34052..34420
                     /gene="rplN"
                     /locus_tag="ACL3EZ_000320"
     CDS             34052..34420
                     /gene="rplN"
                     /locus_tag="ACL3EZ_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HGR0391960.1"
                     /translation="MIQTETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVK
                     QATPGGAVKKGDVVKAVIVRTKSGARRADGSYIKFDENAAVIIREDKTPRGTRIFGPV
                     ARELREGGFMKIVSLAPEVL"
     gene            34498..34803
                     /gene="rplX"
                     /locus_tag="ACL3EZ_000321"
     CDS             34498..34803
                     /gene="rplX"
                     /locus_tag="ACL3EZ_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HGR0391961.1"
                     /translation="MFVKKGDKVRVIAGKDKGTEAVVLTALPKVNKVIVEGVNIVKKH
                     QRPTNELPQGGIIEKEAAIHVSNVQVLDKNGVAGRVGYKFVDGKKVRYNKKSGEVLD"
     gene            34827..35369
                     /gene="rplE"
                     /locus_tag="ACL3EZ_000322"
     CDS             34827..35369
                     /gene="rplE"
                     /locus_tag="ACL3EZ_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HGR0391962.1"
                     /translation="MANRLKEKYLNEVVPALTEQFNYSSVMAVPKVDKIVLNMGVGEA
                     VSNAKSLEKAAEELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLD
                     KLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEINFDDVDKTRGLDIVIVTT
                     ANTDEESRALLTGLGMPFAK"
     gene            35387..35656
                     /gene="rpsN"
                     /locus_tag="ACL3EZ_000323"
     CDS             35387..35656
                     /gene="rpsN"
                     /locus_tag="ACL3EZ_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HGR0391963.1"
                     /translation="MAKKSMVAREAKRQKIVDRYAEKRAALKAAGDYEGLSKLPRNAS
                     PTRLHNRCRVTGRPHSVYRKFGLSRIAFRELAHKGQIPGVTKASW"
     gene            35941..36339
                     /gene="rpsH"
                     /locus_tag="ACL3EZ_000324"
     CDS             35941..36339
                     /gene="rpsH"
                     /locus_tag="ACL3EZ_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009754342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HGR0391964.1"
                     /translation="MVMTDPIADFLTRIRNANQAKHEVLEVPASNIKKGIAEILKREG
                     FVKNVEIIEDDKQGVIRVFLKYGPNGEKVITNLKRVSKPGLRVYKKREDLPKVLNGLG
                     IAILSTSEGLLTDKEARQKNVGGEVIAYVW"
     gene            36531..37067
                     /gene="rplF"
                     /locus_tag="ACL3EZ_000325"
     CDS             36531..37067
                     /gene="rplF"
                     /locus_tag="ACL3EZ_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HGR0391965.1"
                     /translation="MSRIGNKVIVLPAGVELANNDNVVTVKGPKGELTREFSKDIEIR
                     VEGTEITLHRPNDSKEMKTIHGTTRALLNNMVVGVSEGFKKELEMRGVGYRAQLQGSK
                     LVLAVGKSHPDEVEAPEGITFELPNPTTIVVSGISKEVVGQTAAYVRSLRSPEPYKGK
                     GIRYVGEFVRRKEGKTGK"
     gene            37151..37507
                     /gene="rplR"
                     /locus_tag="ACL3EZ_000326"
     CDS             37151..37507
                     /gene="rplR"
                     /locus_tag="ACL3EZ_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HGR0391966.1"
                     /translation="MISKPDKNKLRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQV
                     IDDVAGVTLASASTLDKEVSKGTKTEQAVAVGKLVAERANAKGISEVVFDRGGYLYHG
                     RVKALADAARENGLKF"
     gene            37525..38019
                     /gene="rpsE"
                     /locus_tag="ACL3EZ_000327"
     CDS             37525..38019
                     /gene="rpsE"
                     /locus_tag="ACL3EZ_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HGR0391967.1"
                     /translation="MAFKDNAVELEERVVAVNRVTKVVKGGRRLRFAALVVVGDHNGR
                     VGFGTGKAQEVPEAIRKAVDDAKKNLIEVPMVGTTIPHEVLSEFGGAKVLLKPAVEGS
                     GVAAGGAVRAVVELAGVADITSKSLGSNTPINIVRATVEGLKQLKRAEEIAALRGISV
                     SDLA"
     gene            38033..38215
                     /gene="rpmD"
                     /locus_tag="ACL3EZ_000328"
     CDS             38033..38215
                     /gene="rpmD"
                     /locus_tag="ACL3EZ_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HGR0391968.1"
                     /translation="MAQIKITLTKSPIGRIPSQRKTVVALGLGKLNSSVIKEDNAAIR
                     GMITAVSHLVTVEEVN"
     gene            38360..38800
                     /gene="rplO"
                     /locus_tag="ACL3EZ_000329"
     CDS             38360..38800
                     /gene="rplO"
                     /locus_tag="ACL3EZ_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HGR0391969.1"
                     /translation="MKLHELKPAEGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNINAKEYAIVNLDQLNVFEDGAEVTPVVLIEAGIV
                     KAEKSGIKILGNGELTKKLTVKAAKFSKSAEEAITAKGGSVEVI"
     gene            38813..40123
                     /gene="secY"
                     /locus_tag="ACL3EZ_000330"
     CDS             38813..40123
                     /gene="secY"
                     /locus_tag="ACL3EZ_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HGR0391970.1"
                     /translation="MFFKLLREALKVKQVRSKILFTIFIVLVFRIGTSITVPGVNANS
                     LNALSGLSFLNMLSLVSGNALKNFSIFALGVSPYITASIVVQLLQMDILPKFVEWGKQ
                     GEVGRRKLNQATRYIALVLAFVQSIGITAGFNTLAGAQLIKTALTPQVFLTIGIILTA
                     GSMIVTWLGEQITDKGYGNGVSMIIFAGIVSSIPEMIQGIYVDYFVNVPSSRITSSII
                     FVIILIITVLLIIYFTTYVQQAEYKIPIQYTKVAQGAPSSSYLPLKVNPAGVIPVIFA
                     SSITAAPAAILQFLSATGHDWAWVRVAQEMLATTSPTGIAMYALLIILFTFFYTFVQI
                     NPEKAAESLQKSGAYIHGVRPGKGTEEYMSKLLRRLATVGSLFLGVISILPIAAKDVF
                     GLSDVVAFGGTSLLIIISTGIEGIKQLEGYLLKRKYVGFMDRTE"
     gene            40274..40912
                     /locus_tag="ACL3EZ_000331"
     CDS             40274..40912
                     /locus_tag="ACL3EZ_000331"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HGR0391971.1"
                     /translation="MNLLIMGLPGAGKGTQAAKIVEQFHVAHISTGDMFRAAMANQTE
                     MGVLAKSYIDKGELVPDEVTNGIVKERLSQDDIKETGFLLDGYPRTIEQAHALDKTLA
                     ELGIELEGIINIEVNPDSLLERLSGRIIHRVTGETFHKVFNPPVDYKEEDYYQREDDK
                     PETVKRRLDVNIAQGEPIIAHYRAKGLVHDIEGNQDINDVFSDIEKVLTNLK"
     gene            41029..41247
                     /gene="infA"
                     /locus_tag="ACL3EZ_000332"
     CDS             41029..41247
                     /gene="infA"
                     /locus_tag="ACL3EZ_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HGR0391972.1"
                     /translation="MAKDDVIEVEGKVVDTMPNAMFTVELENGHQILATVSGKIRKNY
                     IRILAGDRVTVEMSPYDLTRGRITYRFK"
     gene            41272..41388
                     /gene="rpmJ"
                     /locus_tag="ACL3EZ_000333"
     CDS             41272..41388
                     /gene="rpmJ"
                     /locus_tag="ACL3EZ_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HGR0391973.1"
                     /translation="MKVRPSVKPICEYCKVIRRNGRVMVICPANPKHKQRQG"
     gene            41406..41771
                     /gene="rpsM"
                     /locus_tag="ACL3EZ_000334"
     CDS             41406..41771
                     /gene="rpsM"
                     /locus_tag="ACL3EZ_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HGR0391974.1"
                     /translation="MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGISEDVR
                     VRDLTSDQEDAIRREVDAIKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGKAVAIAGKKK"
     gene            41789..42172
                     /gene="rpsK"
                     /locus_tag="ACL3EZ_000335"
     CDS             41789..42172
                     /gene="rpsK"
                     /locus_tag="ACL3EZ_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HGR0391975.1"
                     /translation="MAKPTRKRRVKKNIESGIAHIHATFNNTIVMITDVHGNAIAWSS
                     AGALGFKGSRKSTPFAAQMASEAAAKSAQEHGLKSVEVTVKGPGSGRESAIRALAAAG
                     LEVTAIRDVTPVPHNGARPPKRRRV"
     gene            42215..43150
                     /locus_tag="ACL3EZ_000336"
     CDS             42215..43150
                     /locus_tag="ACL3EZ_000336"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HGR0391976.1"
                     /translation="MIEFEKPNITKIDENKDYGKFVIEPLERGYGTTLGNSLRRVLLA
                     SLPGAAVTSINIDGVLHEFDTVPGVREDVMQIILNIKGIAVKSYVEDEKIIELDVEGP
                     AEVTAGDILTDSDIEIVNPDHYLFTIGEGSSLKATMTVNSGRGYVPADENKKDNAPVG
                     TLAVDSIYTPVTKVNYQVEPARVGSNDGFDKLTLEILTNGTIIPEDALGLSARILTEH
                     LDLFTNLTEIAKSTEVMKEADTESDDRILDRTIEELDLSVRSYNCLKRAGINTVHDLT
                     EKSEAEMMKVRNLGRKSLEEVKLKLIDLGLGLKDK"
     gene            43162..43548
                     /gene="rplQ"
                     /locus_tag="ACL3EZ_000337"
     CDS             43162..43548
                     /gene="rplQ"
                     /locus_tag="ACL3EZ_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HGR0391977.1"
                     /translation="MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTV
                     EKMITLGKRGDLHARRQAAAFVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAER
                     NGGYTRILKTEPRRGDAAPMAIIELV"
     gene            43813..44079
                     /locus_tag="ACL3EZ_000338"
     CDS             43813..44079
                     /locus_tag="ACL3EZ_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002905356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HGR0391978.1"
                     /translation="MKAIITVVGKDKSGIVAGVSGKIAELGLNIDDISQTVLDEYFTM
                     MAVVSSDEKQDFTYLRNEFEAFGQTLNVKINIQSAAIFEAMYNI"
     gene            44089..45426
                     /locus_tag="ACL3EZ_000339"
     CDS             44089..45426
                     /locus_tag="ACL3EZ_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HGR0391979.1"
                     /translation="MDIRQVTETIAMIEEQNFDIRTITMGISLLDCIDPNINRAAEKI
                     YQKITTKAANLVAVGDEIAAELGIPIVNKRVSVTPISLIGAATDATDYVVLAKALDKA
                     AKEIGVDFIGGFSALVQKGYQKGDEILINSIPRALAETDKVCSSVNIGSTKSGINMTA
                     VADMGRIIKETANLSDMGVAKLVVFANAVEDNPFMAGAFHGVGEADVIINVGVSGPGV
                     VKRALEKVRGQSFDVVAETVKKTAFKITRIGQLVGQMASERLGVEFGIVDLSLAPTPA
                     VGDSVARVLEEMGLETVGTHGTTAALALLNDQVKKGGVMACNQVGGLSGAFIPVSEDE
                     GMIAAVQNGSLNLEKLEAMTAICSVGLDMIAIPEDTPAETIAAMIADEAAIGVINMKT
                     TAVRIIPKGREGDMIEFGGLLGTAPVMKVNGASSVDFISRGGQIPAPIHSFKN"
     gene            45670..46362
                     /locus_tag="ACL3EZ_000340"
     CDS             45670..46362
                     /locus_tag="ACL3EZ_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016791 - phosphatase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HGR0391980.1"
                     /translation="MVKVRLYLVRHGKTMFNTIGRAQGWSDTPLTAEGERGIQELGIG
                     LRESDLQFERAYSSDSGRTIQTMGIILEELGLQGKIPYRMDKRIREWCFGSFDGAYDG
                     DLFMGIIPRIFNVDHVHQLSYAELAEGLVEVDTAGWAEGWEKLSGRIKEGFEMIAKEM
                     EDQGGGNALVVSHGMTIGTIVYLINGMHPHGLDNGSVTILEYEDGQFRVEVVGDRSYR
                     ELGREKMEEGSI"
     gene            complement(46465..48110)
                     /locus_tag="ACL3EZ_000341"
                     /pseudo
     CDS             complement(46465..48110)
                     /locus_tag="ACL3EZ_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520796.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
     gene            complement(48100..49175)
                     /locus_tag="ACL3EZ_000342"
                     /pseudo
     CDS             complement(48100..49175)
                     /locus_tag="ACL3EZ_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001289362.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(49188..50189)
                     /locus_tag="ACL3EZ_000343"
                     /pseudo
     CDS             complement(49188..50189)
                     /locus_tag="ACL3EZ_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003085230.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
     gene            complement(50507..50731)
                     /locus_tag="ACL3EZ_000344"
                     /pseudo
     CDS             complement(50507..50731)
                     /locus_tag="ACL3EZ_000344"
                     /inference="COORDINATES: protein motif:HMM:NF024242.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            complement(50779..51555)
                     /locus_tag="ACL3EZ_000345"
     CDS             complement(50779..51555)
                     /locus_tag="ACL3EZ_000345"
                     /EC_number="1.97.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000406168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0043687 - post-translational protein
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HGR0391981.1"
                     /translation="MEISKGIIFNIQHFSIHDGPGIRTTVFLKGCPLRCPWCSNPESQ
                     RMKPEKMKDAQREKFTLVGEEKTVEEIITEVLKDKEFYEESGGGLTLSGGEIFAQFEF
                     AKAILKSAKEHHIHTAIETTAFVDHEKFIDLIQYVDFIYTDLKHYNSIKHKKVTGVFN
                     QMIIKNIHYAFSQNKTIVLRIPVIPNFNNSLEDAEKFATLFNSLNIDQVQLLPFHQFG
                     ENKYRLLNRKYEMDGVNALHPEDLIDYQKVFLNHHINCYF"
     gene            51677..52423
                     /locus_tag="ACL3EZ_000346"
     CDS             51677..52423
                     /locus_tag="ACL3EZ_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HGR0391982.1"
                     /translation="MKRLEQIIKLVSEYEKIDVNTLSEKLNVSKVTIRKDLDKLESKG
                     LLHREHGYAVLNSGDDLNVRLSINYEIKRKIVQEAVKLVSDNETIMIESGSTCALLAE
                     EICKQKRNVTIVTNSFFIANFVRAYDSCRIIVLGGEFQKDSQVTVGPLLKEMIQTFHV
                     HQAFVGTDGYDKEMGFTGKDLMRSEVVQYISAASDKVIVLTDSSKFDKRGTVRRFALS
                     QVYEVITDEKLSKQNIATLENAGIMVKVVS"
     gene            52436..53416
                     /locus_tag="ACL3EZ_000347"
     CDS             52436..53416
                     /locus_tag="ACL3EZ_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HGR0391983.1"
                     /translation="MNQDRNKLLSKIAYLYYIENLNQSQIAAKLGIYRTSISRMLTEA
                     RNAGIVKIEIENFDTNMFKLENYVKEKYGLESLEIIPNEFDDNPTILSERISQVAAGV
                     LRNLIDDNMKIGFSWGKSLSNLVDLIHSKSVRNVHFYPLAGGPSHIHAKYHVNTLIYE
                     MSRKFHGECTFMNATIVQENKLLADGILQSRYFENLKNSWKDLDIAVVGIGDFSNKGK
                     HQWLDMLTEDDFKELTKVKTVGEICCRFFDSKGKEVYENLQERTIAISLEDLKNIPQS
                     LAVAYGDTKVSSILSVLRANLVNHLITDKNTILKVLEEDGDLTFREILGE"
     gene            53611..53931
                     /locus_tag="ACL3EZ_000348"
     CDS             53611..53931
                     /locus_tag="ACL3EZ_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HGR0391984.1"
                     /translation="MEIIVPDQIIMGLILYAGDAKQHIYKALDYIKNGTCERCEEEIQ
                     LADAALLEAHNLQTKFLAQEASGTKTEITALFVHSQDHLMTSMTEINLIKEIISLRKE
                     LHKK"
     gene            53977..54285
                     /locus_tag="ACL3EZ_000349"
     CDS             53977..54285
                     /locus_tag="ACL3EZ_000349"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000238716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGR0391985.1"
                     /translation="MVKIGLFCAAGFSTGMLVNNMKIAAQSSGVEAEIEAFSQSKLAD
                     YAPNIDVALLGPQVAYTLDKSKEICDKCDVPIAVIPMMDYGMLDGKKVLDLALSLISG
                     "
     gene            54302..55600
                     /locus_tag="ACL3EZ_000350"
     CDS             54302..55600
                     /locus_tag="ACL3EZ_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HGR0391986.1"
                     /translation="MSKMDVQKIIAPMMKFVNMRGIIALKDGMLAILPLTVVGSLFLI
                     MGQLPFEGLNKSIASVFGANWTEPFMQVYSGTFAIMGLISCFSIAYSYAKNSGVEALP
                     AGVLSVSAFFILLRSSYIPKQGEAIGDAISKVWFGGQGIIGAIIIGLVVGSIYTFFIK
                     RKIVIKMPEQVPQAIAKQFEAMIPAFVIFLSSMIVYILAKSLTNGGTFIEMIYSAIQV
                     PLQGLTGSLYGAIGIAFFISFLWWFGVHGQSVVNGVVTALLLSNLDANKAMLASANLS
                     LENGAHIVTQQFLDSFLILSGSGITFGLVVAMLFAAKSKQYQALGKVAAFPAIFNVNE
                     PVVFGFPIVMNPVMFVPFILVPVLAAVIVYGAIATGFMQPFSGVTLPWSTPAILSGFL
                     VGGWQGVVTQLLVLVISTVVYFPFFKIQDRLAYQNEIKQS"
     gene            55751..58189
                     /locus_tag="ACL3EZ_000351"
     CDS             55751..58189
                     /locus_tag="ACL3EZ_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HGR0391987.1"
                     /translation="MVNTEVARTTIKTEYFGSLTERMNKYREDVLNKKPYIDAERAVL
                     ATRAYERYKEQPNVLKRAYMLKEILENMSIYIEEESMIAGNQASSNKDAPIFPEYTLE
                     FVLNELDLFEKRDGDVFYITEETKEQLRSIAPFWENNNLRARAGALLPEEVSVYMETG
                     FFGMEGKMNSGDAHLAVNYQKLLQFGLRGFEERARKAKVALDLTDPASIDKYHFYDSI
                     FIVIDAIKVYAKRFVALAKSLAENANPKRKKELLEIADICSRVPYEPATTFAEAIQSV
                     WFIQCILQIESNGHSLSYGRFDQYMYPYMKADLESGKETEDSIVERLTNLWIKTITIN
                     KVRSQSHTFSSAGSPLYQNVTIGGQTRDKKDAVNPLSYLVLKSVAQTHLPQPNLTVRY
                     HAGLDARFMNECIEVMKLGFGMPAFNNDEIIIPSFIAKGVLEDDAYDYSAIGCVETAV
                     PGKWGYRCTGMSYMNFPKVLLITMNDGIDPASGKRFAPSFGHFKDMKNFSELENAWDK
                     TLRYLTRMSVIVENSIDLSLEREVPDILCSALTDDCIGRGKHLKEGGAVYDYISGLQV
                     GIANLSDSLAAIKKLVFEEERISPSQLWHALETDYAREEGKVIQEMLIHDAPKYGNDD
                     DYADKLVTAAYDIYVDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGRGTLATPDG
                     RNAGTPLAEGCSPSHNMDQHGPTSVLKSVSKLPTDEIVGGVLLNQKVNPQTLAKEEDK
                     LKLIALLRTFFNRLHGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFNVLSK
                     ATQDDIIGRTEHTL"
     gene            58208..58876
                     /locus_tag="ACL3EZ_000352"
     CDS             58208..58876
                     /locus_tag="ACL3EZ_000352"
                     /EC_number="4.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HGR0391988.1"
                     /translation="MEFMLDTLNLDEIKKWSEILPLAGVTSNPTIAKREGSINFFERI
                     KDVRELIGSTPSIHVQVISQDFEGILKDAHKIRRQAGDDIFIKVPVTPAGLRAIKALK
                     KEGYHITATAIYTVIQGLLAIEAGADYLAPYYNRMENLNIDSNSVIRQLALAIDRQNS
                     PSKILAASFKNVAQVNNALAADAHAVTAGADVFESAFAMPSIQKAVDDFSDDWFVIQN
                     SRSI"
     gene            58894..59982
                     /locus_tag="ACL3EZ_000353"
     CDS             58894..59982
                     /locus_tag="ACL3EZ_000353"
                     /EC_number="1.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0008888 - glycerol dehydrogenase (NAD+)
                     activity [Evidence IEA];
                     GO_function: GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HGR0391989.1"
                     /translation="MRIFASPSRYIQGENALFENAKSILDLGNCPILLCDQLVYDIVG
                     KRFEDYLHRYGFHIVLALFNGEASDNEINRVVALAEKENCDSIIGLGGGKTIDSAKAI
                     ADLIEKPVIIAPTIASTDAPVSALSVIYTDEGAFDHYLFYSKNPDLVLVDTKVISQAP
                     KRLLASGIADGLATWVEARAVMQANGKTMLGQQQTLAGVAIAKKCEETLFADGLQAMA
                     ACEAKVVTPALENIVEANTLLSGLGFESGGLAAAHAIHNGFTALTGDIHHLTHGEKVA
                     YGTLVQLLLENRPKEELDKYIEFYKKIGMPTTLKEMHLDQVGYDDLIKVGKQATMEGE
                     TIHQMPFKISPSDVAQAIIAVDAYVNSK"
     gene            60437..62938
                     /gene="leuS"
                     /locus_tag="ACL3EZ_000354"
     CDS             60437..62938
                     /gene="leuS"
                     /locus_tag="ACL3EZ_000354"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004823 - leucine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006429 - leucyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HGR0391990.1"
                     /translation="MSFYNHKEIEPKWQGYWAEHHTFKTGTDASKPKFYALDMFPYPS
                     GAGLHVGHPEGYTATDILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA
                     ENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
                     ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLNDLDELDWSESIKD
                     MQRNWIGKSTGANVTFKVKGTDKEFTVFTTRPDTLFGATFTVLAPEHELVDAITSSEQ
                     AEAVADYKHQASLKSDLARTDLAKEKTGVWTGAYAINPVNGKEMPIWIADYVLASYGT
                     GAVMAVPAHDQRDWEFAKQFDLPIVEVLEGGDVKEAAYTEDGLHVNSDFLDELNKEDA
                     IAKIVAWLEEKGCGQEKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPETELPLV
                     LPVTKDIRPSGTGESPLANLTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPH
                     NTEKLADEDLLKQWLPVDIYVGGAEHAVLHLLYARFWHKFLYDLGVVPTKEPFQKLFN
                     QGMILGTSYRDHRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDV
                     VEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITSKEILAENNGALD
                     KVYNETVKAVTEQIDSLKFNTAIAQLMVFVNAANKEDKLYVDYAKGFIQLIAPFAPHL
                     AEELWQTVAATGESISYVTWPTWDESKLVEDEIEIVVQIKGKVRAKLMVAKDLSREEL
                     QEIALADEKVKAEIDGKEIVKVISVPNKLVNIVVK"
     gene            63077..63919
                     /locus_tag="ACL3EZ_000355"
                     /pseudo
     CDS             63077..63919
                     /locus_tag="ACL3EZ_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081168.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            63975..64670
                     /locus_tag="ACL3EZ_000356"
     CDS             63975..64670
                     /locus_tag="ACL3EZ_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001144916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family protein"
                     /protein_id="HGR0391991.1"
                     /translation="MPVNEYGQMIGESMEGYTPGALPSIDFLEGRYARIEALSVEKHA
                     EDLLAVYGPDTPREMWTYLFQEPVADMGELVSLLNQMLARKDRFYYAIIDKATGKALG
                     TFSLMRIDQNNRVIEVGAVTFSPELRGTRIGTEAQYLLARYIFEELNYRRYEWKCDAL
                     NLPSRRVAERLGFVYEGTFRQAVVYKGRTRDTDWLSMIDMDWPQVKDRLETWLRPENF
                     DKNGQQYKSLREL"
     gene            64682..65098
                     /locus_tag="ACL3EZ_000357"
     CDS             64682..65098
                     /locus_tag="ACL3EZ_000357"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR0391992.1"
                     /translation="MITIKKQEIVKLEDVLHLYQAVGWTNYTHQPEMLEHALSHSLVI
                     YLALDGDAVVGLIRLVGDGFSSVFVQDLIVLPIYQRQGIGSALMKEALKDYKDAYQVQ
                     LVTEETEKNVGFYRSMGFEILSTYNCIGMTWANREK"
     gene            complement(65913..66005)
                     /locus_tag="ACL3EZ_000358"
     CDS             complement(65913..66005)
                     /locus_tag="ACL3EZ_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HGR0391993.1"
                     /translation="MMELVLKTIIGPIVVGVVLRIVDKWLNKDK"
     gene            66139..67137
                     /gene="ruvB"
                     /locus_tag="ACL3EZ_000359"
     CDS             66139..67137
                     /gene="ruvB"
                     /locus_tag="ACL3EZ_000359"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0009378 - four-way junction helicase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HGR0391994.1"
                     /translation="MSRILDNEIMGDEELVERTLRPQYLREYIGQDKVKDQLQIFIEA
                     AKMRDEALDHVLLFGPPGLGKTTMAFVIANELGVNLKQTSGPVIEKAGDLVAILNELE
                     PGDVLFIDEIHRLPMSVEEVLYSAMEDFYIDIMIGAGEGSRSVHLELPPFTLIGATTR
                     AGMLSNPLRARFGITGHMEYYAHADLTEIVERTADIFEMEITHEAASELALRSRGTPR
                     IANRLLKRVRDFAQIMGNGVIDDIITDKALTMLDVDHEGLDYVDQKILRTMIEMYSGG
                     PVGLGTLSVNIAEERETVEDMYEPYLIQKGFIMRTRSGRVATAKAYEHLGYEYSEK"
     gene            67118..67690
                     /locus_tag="ACL3EZ_000360"
                     /pseudo
     CDS             67118..67690
                     /locus_tag="ACL3EZ_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001098890.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
     gene            67921..68679
                     /locus_tag="ACL3EZ_000361"
     CDS             67921..68679
                     /locus_tag="ACL3EZ_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HGR0391995.1"
                     /translation="MFGFFKKDKAVEVEVPTQVPAHIGIIMDGNGRWAKKRMQPRVFG
                     HKAGMEALQTVTKAANKLGVKVITVYAFSTENWTRPDQEVKFIMNLPVEFYDNYVPEL
                     HANNVKIQMIGETDRLPKQTFEALTKAEELTKNNTGLILNFALNYGGRAEITQALKLI
                     SQDVLDAKINPGDITEELIGNYLFTQHLPKDLRDPDLIIRTSGELRLSNFLPWQGAYS
                     ELYFTDTLWPDFDEAALQEAILAYNRRHRRFGGV"
     gene            68688..69491
                     /locus_tag="ACL3EZ_000362"
     CDS             68688..69491
                     /locus_tag="ACL3EZ_000362"
                     /EC_number="2.7.7.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004605 - phosphatidate
                     cytidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0016024 - CDP-diacylglycerol biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HGR0391996.1"
                     /translation="MTQDLQKRTLFAGIALAIFLPILMIGGLLLQIAIGIIAMLAMHE
                     LLKMRGLETMTMEGLLTLFATFALTIPLENYLTFLPVDGNVVAYSVLISIMLGTTVFS
                     KSYTIEDAVFPLAMSFYVGFGFNALLDARVAGLDKALLALCIVWATDSGAYLVGMNYG
                     KRKLAPRVSPNKTLEGALGGILGAILVTIIFMIVDSTVALPYGIYKMSVFAIFFSIAG
                     QFGDLLESSIKRHFGVKDSGKFIPGHGGVLDRFDSMLLVFPIMHLFGLF"
     gene            69513..70772
                     /gene="rseP"
                     /locus_tag="ACL3EZ_000363"
     CDS             69513..70772
                     /gene="rseP"
                     /locus_tag="ACL3EZ_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HGR0391997.1"
                     /translation="MLGILTFILVFGIIVVVHEFGHFYFAKKSGILVREFAIGMGPKI
                     FAHIGKDGTAYTIRILPLGGYVRMAGWGDDTTEIKTGTPVSLTLADDGKVKRINLSGK
                     KLDQTALPMQVTQFDFEDKLFIKGLVLEEEKTFAVDHDATVVEADGTEVRIAPLDVQY
                     QNATIWGKLITNFAGPMNNFILGVVVFWVLIFMQGGVRDVDTNQFHIMPQGALAKVGV
                     PETAQITKIGSHEVSNWESLIQAVETETKDKTAPTLDVTISEKGSDKQVTVTPEDSQG
                     RYLLGVQPGVKSDFLSMFVGGFTTAADSALRILSALKNLIFQPDLNKLGGPVAIFKAS
                     SDAAKNGIENILYFLAMISINIGIFNLIPIPALDGGKIVLNILEAIRRKPLKQEIETY
                     VTLAGVVIMVVLMIAVTWNDIMRLFFR"
     gene            70785..72638
                     /locus_tag="ACL3EZ_000364"
     CDS             70785..72638
                     /locus_tag="ACL3EZ_000364"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0002161 - aminoacyl-tRNA editing activity
                     [Evidence IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0004827 - proline-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006418 - tRNA aminoacylation for protein
                     translation [Evidence IEA];
                     GO_process: GO:0006433 - prolyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HGR0391998.1"
                     /translation="MKQSKMPIPTLREMPSDAQVISHALMLRAGYVRQVSAGVYSYLP
                     LANRVIEKAKNIMRQEFEKIGAVEMLAPALLSAELWRESGRYETYGEDLYKLKNREKS
                     DFILGPTHEETFTAIVRDSVKSYKQLPLNLYQIQPKYRDEKRPRNGLLRTREFIMKDA
                     YSFHANYDSLDSVYDEYKAAYERIFTRSGLDFKAIIGDGGAMGGKDSQEFMAITSART
                     DLDRWVVLDKSVASFDEIPAEVQEEIKAELLKWIVSGEDTIAYSSESSYAANLEMATN
                     EYKPSNRVVAEEEVTRVATPDVKSIDEVAAFLNVPEEQTIKTLFYIADGELVAALLVG
                     NDQLNEVKLKNHLGADFFDVASEEEVANVVQAGFGSLGPVGLPENIKIIADRKVQDVR
                     NAVVGANEDGYHLTGVNPGRDFTAEYVDIREVREGEISPDGQGVLNFARGIEIGHIFK
                     LGTRYSASMGADVLDENGRAVPIIMGCYGIGVSRLLSAVMEQHARLFVNKTPKGEYRY
                     AWGINFPKELAPFDVHLITVNVKDEEAQALTEKLEASLMGAGYEVLTDDRNERVGVKF
                     SDSDLIGLPIRITVGKKAADGIVEVKIKATGDTIEVHADNVLETLEILSKK"
     gene            72738..74117
                     /gene="bglA"
                     /locus_tag="ACL3EZ_000365"
     CDS             72738..74117
                     /gene="bglA"
                     /locus_tag="ACL3EZ_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000943526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HGR0391999.1"
                     /translation="MLRFPKDFVWGSSTSGPQTEGRVAGDGKGDNLWDYWFQVEPNRY
                     YNGIGSDKTSTFYENWERDIELLLETGHTVFRTSIQWSRIFPQGCGKVNPQGVDFYRK
                     VFEAIKAKGIRLLVNLYHFDLPFALQEDGDGWENKATVSAYEDYARFCFETYGDLVDQ
                     WITFNEPIVPVEFGYFYDAHYPHKVDAEAAVKVAYHTQLASSRAVKACHELLPDSKIG
                     IVLNLTPAYPRSQHPADVKAARIAALFQAQSFLDPSVLGTYPQELVEILHEHGLLPDA
                     TEEELELIRDNTVDFLGVNYYQPLRVMAPRFAKHPDSPLLPEHFYEPYVMPGRKINSH
                     RGWEIYEQGIYDIAQNIKENYGNIEWMLTENGMGVEGEEKFRQDGMIQDDYRIDFVKG
                     HLRELHRAIEDGANCKGYLIWTFIDCWSWLNSYKNRYGLVELDLETQERRLKKSGHWF
                     KELSDNNGF"
     gene            74309..76117
                     /gene="glmS"
                     /locus_tag="ACL3EZ_000366"
     CDS             74309..76117
                     /gene="glmS"
                     /locus_tag="ACL3EZ_000366"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014621492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004360 - glutamine-fructose-6-phosphate
                     transaminase (isomerizing) activity [Evidence IEA];
                     GO_process: GO:1901137 - carbohydrate derivative
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HGR0392000.1"
                     /translation="MCGIVGVVGNTNATDILIQGLEKLEYRGYDSAGIFVLDGADNHL
                     VKAVGRIAELSAKTAGVEGTTGIGHTRWATHGKPTEDNAHPHRSETERFVLVHNGVIE
                     NYLEIKEEYLAGHHFKGQTDTEIAVHLIGKFAEEEGLSVLEAFKKALHIIRGSYAFAL
                     VDSQDPEVIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETNQYMEIHDQELVIVKADS
                     VEVQDYDGNRRERASYTAELDLSDIGKGTYPYYMLKEIDEQPTVMRKLIQAYTDEAGQ
                     VVVDPDIIKAVQDADRIYILAAGTSYHAGFASKKMLEELTDTPVELGISSEWGYSMPL
                     LSKKPLFIFISQSGETADSRQVLVKANEMGIPSLTVTNVPGSTLSREANYTMLLHAGP
                     EIAVASTKAYTAQIAALAFLAKAVGEANGNAKAQAFDLVHELSIVAQSIESTLSEKET
                     IEAKVRELLETTRNAFYIGRGQDYYVAMEASLKLKEISYIQCEGFAAGELKHGTIALI
                     EEGTPVLALLSDPVLANHTRGNIQEVAARGAKVLTIAEENVAKDTDDIVLTTVHPYLS
                     PISMVVPTQLVAYFATLHRGLDVDKPRNLAKSVTVE"
     gene            76236..77285
                     /locus_tag="ACL3EZ_000367"
     CDS             76236..77285
                     /locus_tag="ACL3EZ_000367"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HGR0392001.1"
                     /translation="MVELGISTFGEITELEGTGQTYSHAERIRQLVAEIELADKVGLD
                     VYGIGEHHRADFAVSAPEIVLAAGAVNTKKIRLTSAVSILSSMDPIRLFQQYATIDAL
                     SNGRAEIMAGRGSFTESFPLFGYDLKDYDSLFDEKLDLLQLVNEKTKLDWQGRLTQTI
                     AGKEVYPRPVQDKLPLWIATGGHVESTVKIAQAGLPIVYAIIGGNPRYFKKLIQAYRE
                     IGSEAGHADKDLKVGAHSWGWIAEDGEQAVKDYFHPTKQVVDAISKDRPHWQELRYEQ
                     YLEQVGPNGAMFVGNPDQVAEKLIRMIEDLGLDRFMLHLPLGSMPHDQVLRAIELFGT
                     QVAPKVRAYFAMKEA"
     gene            complement(77385..81182)
                     /gene="spuA"
                     /locus_tag="ACL3EZ_000368"
     CDS             complement(77385..81182)
                     /gene="spuA"
                     /locus_tag="ACL3EZ_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored pullulanase SpuA"
                     /protein_id="HGR0392002.1"
                     /translation="MRKTPSHTEKKMVYSIRSLKNGTGSVLIGASLVLLAMATPTISS
                     DESTPTTNEPNNRNTTTLAQPLTDTAAGSGKNESDISSPRNANASLEKTEEKPATEPT
                     TSTSPVTTETKAEEPIEDNYFRIHVKKLPEENKDAQGLWTWDDVEKPSENWPNGALSF
                     KDAKKDDYGYYLDVKLKGEQAKKISFLINNTAGKNLTGDKSVEKLVPKMNEAWLDQDY
                     KVFSYEPQPAGTVRVNYYRTDGNYDKKSLWYWGDVKNPSSAQWPDGTDFTATGKYGRY
                     IDIPLNEAAREFGFLLLDESKQGDDVKIRKENYKFTDLKNHSQIFLKDDDESIYTNPY
                     YVHDIRMTGAQHVGTSSIESSFSTLVGAKKEDILKHSNITNHLGNKVTITDVAIDEAG
                     KKVTYSGDFSDTKHPYTVSYNSDQFTTKTSWRLKDETYSYDGKLGADLKEEGKQVDLT
                     LWSPSADKVSVVVYDKNDPDKVVGTVALEKGERGTWKQTLDSTNKLGITDFTGYYYQY
                     QIERQGKTVLALDPYAKSLAAWNSDDAKIDDAHKVAKAAFVDPAKLGPQDLTYGKIHN
                     FKTREDAVIYEAHVRDFTSDPAIAKDLTKPFGTFEAFIEKLDYLKDLGVTHIQLLPVL
                     SYYFVNELKNHERLSDYTSSNSNYNWGYDPQNYFSLTGMYSSDPKNPEKRIAEFKNLI
                     NEIHKRGMGAILDVVYNHTAKVDIFEDLEPNYYHFMDADGTPRTSFGGGRLGTTHHMT
                     KRLLVDSIKYLVDTYKVDGFRFDMMGDHDAASIEEAYKAARALNPNLIMLGEGWRTYA
                     GDENMPTKAADQDWMKHTDTVAVFSDDIRNNLKSGYPNEGQPAFITGGKRDVNTIFKN
                     LIAQPTNFEADSPGDVIQYIAAHDNLTLFDIIAQSIKKDPSKAENYAEIHRRLRLGNL
                     MVLTAQGTPFIHSGQEYGRTKQFRDPAYKTPVAEDKVPNKSHLLRDKDGNPFDYPYFI
                     HDSYDSSDAVNKFDWTKATDGKAYPENVKSRDYMKGLIALRQSTDAFRLKSLQDIKDR
                     VHLITVPGQNGVEKEDVVIGYQITAPNGDIYAVFVNADEKAREFNLGTAFAHLRNAEV
                     LADENQAGPVGIANPKGLEWTEKGLKLNALTATVLRVSQNGTSHESTAEEKPDSTPSK
                     PEHQNEASHPAHQDPAPEARPDSTKPDAKVADAENKPSQATADSQAEQPAQEAQASSV
                     KEAVRNESVENSSKENIPATPDKQAELPNTGIKNENKLLFAGISLLALLGLGFLLKNK
                     KEN"
     gene            81599..82012
                     /gene="rpsL"
                     /locus_tag="ACL3EZ_000369"
     CDS             81599..82012
                     /gene="rpsL"
                     /locus_tag="ACL3EZ_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HGR0392003.1"
                     /translation="MPTINQLVRKPRKSKVEKSKSPALNVGYNSHKKVQTNVSSPQKR
                     GVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQGRSKYGTKRPKA"
     gene            82032..82502
                     /gene="rpsG"
                     /locus_tag="ACL3EZ_000370"
     CDS             82032..82502
                     /gene="rpsG"
                     /locus_tag="ACL3EZ_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HGR0392004.1"
                     /translation="MSRKNRAPKRDVLPDPLYNSQLVTRLINRVMLDGKRGTAASIVY
                     GAFEQIKEATGNDALEVFETAMENIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVTIARLRGEHTMQDRLAKEILDAANNTGAAVKKREDTHRMAEANRAFAHFRW"
     gene            82927..85008
                     /gene="fusA"
                     /locus_tag="ACL3EZ_000371"
     CDS             82927..85008
                     /gene="fusA"
                     /locus_tag="ACL3EZ_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HGR0392005.1"
                     /translation="MAREFSLEKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWNNHRVNIIDTPGHVDFTIEVQRSLRVLDGA
                     VTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPVGSEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPAEYLDQAQEYREKLIEAV
                     AETDEELMMKYLEGEEITNEELKAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVID
                     YLPSPLDIPAIKGINPDTDAEEIRPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVL
                     QSGSYVLNTSKGKRERIGRILQMHANSRQEIDTVYSGDIAAAVGLKDTTTGDSLTDEK
                     SKIILESINVPEPVIQLMVEPKSKADQDKMGIALQKLAEEDPTFRVETNVETGETVIS
                     GMGELHLDVLVDRMRREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDV
                     WIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLVESMANGVLAGYPMVDVKAKLY
                     DGSYHDVDSSETAFKIAASLSLKEAAKSAQPAILEPMMLVTITVPEENLGDVMGHVTA
                     RRGRVDGMEAHGNSQIVRAYVPLAEMFGYATVLRSASQGRGTFMMVFDHYEDVPKSVQ
                     EEIIKKNKGED"
     gene            85112..89503
                     /locus_tag="ACL3EZ_000372"
     CDS             85112..89503
                     /locus_tag="ACL3EZ_000372"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HGR0392006.1"
                     /translation="MSNSFEILMNQLGMPAEMRQAPALAQANIERVVVHKISKVWEFH
                     FVFSNILPIEIFLELKKGLSEEFSKTGNKAVFEIKARSQEFSNQLLQSYYREAFSEGP
                     CASQGFKSLYQNLQVRAEGNQLFIEGSEAIDKEHFKKNHLPNLAKQLEKFGFPTFNCQ
                     VEKNDVLTQEQEEAFHAENEQIVQAANEEALRAMEQLEQMAPPPAEEKPVFDFQAKKA
                     AAKPKLDKAEITPMIEVTTEENRLVFEGVVFDVEQKVTRTGRVLINFKMTDYTSSFSM
                     QKWVKNEEEAQKFDLIKKNSWLRVRGNVEMNNFTRDLIMNVQDLQEVVHYERKDLMPE
                     GERRVEFHAHTNMSTMDALPEVEEIVATAAKWGHKAVAITDHGNVQSFPHGYKAAKKA
                     GIQLIYGMEANIVEDRVPIVYNEVEMDLSEATYVVFDVETTGLSAIYNDLIQVAASKM
                     YKGNVIAEFDEFINPGHPLSAFTTELTGITDDHVKNAKPLEQVLQEFQEFCKDTVLVA
                     HNATFDVGFMNANYERHGLPKISQPVIDTLEFARNLYPEYKRHGLGPLTKRFGVALEH
                     HHMANYDAEATGRLLFIFIKEVAEKHGVTDLARLNIDLISPDSYKKARIKHATIYVKN
                     QVGLKNIFKLVSLSNTKYFEGVPRIPRTVLDAHREGLILGSACSEGEVFDVVVSQGVD
                     AAVEVAKYYDFIEVMPPAIYAPLIAKEQVKDMEELQTIIKSLIEVGDRLGKPVLATGN
                     VHYIEPEEEIYREIIVRSLGQGAMINRTIGHGEHAQPAPLPKAHFRTTNEMLDEFAFL
                     GEELARKLVIENTNALAEIFEPVEVVKGDLYTPFIDKAEETVAELTYKKAFEIYGNPL
                     PDIVDLRIEKELTSILGNGFAVIYLASQMLVQRSNERGYLVGSRGSVGSSFVATMIGI
                     TEVNPLSPHYVCGQCQYSEFITDGSYGSGFDMPHKDCPNCGHKLSKNGQDIPFETFLG
                     FDGDKVPDIDLNFSGEDQPSAHLDVRDIFGEEYAFRAGTVGTVAAKTAYGFVKGYERD
                     YGKFYRDAEVERLAQGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTAEWQ
                     TTHFNFHDIDENVLKLDVLGHDDPTMIRKLQDLSGIDPNKIPMDDEGVMALFSGTDVL
                     GVTPEQIGTPTGMLGIPEFGTNFVRGMVDETHPTTFAELLQLSGLSHGTDVWLGNAQD
                     LIKQGIADLSTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNGYIE
                     AMKANKVPEWYIESCGKIKYMFPKAHAAAYVMMALRVAYFKVHHPIYYYCAYFSIRAK
                     AFDIKTMGAGLEVIKRRMEEISEKRKNNEASNVEIDLYTTLEIVNEMWERGFKFGKLD
                     LYRSQATEFLIDGDTLIPPFVAMDGLGENVAKQLVRAREEGEFLSKTELRKRGGLSST
                     LVEKMDEMGILGNMPEDNQLSLFDELF"
     gene            89605..89868
                     /locus_tag="ACL3EZ_000373"
     CDS             89605..89868
                     /locus_tag="ACL3EZ_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HGR0392007.1"
                     /translation="MSKMSISIRLDSEVKEQAQQVFSNLGMDMTTAINIFLRQAIQYQ
                     GLPFDVRLDENRKLLQALTDLDQNRNMSQSFESVSDLMEDLRA"
     gene            89861..90139
                     /locus_tag="ACL3EZ_000374"
     CDS             89861..90139
                     /locus_tag="ACL3EZ_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013904578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system YafQ family
                     toxin"
                     /protein_id="HGR0392008.1"
                     /translation="MLKIRYHKQFKKDFKLAMKRGLKAELLEEVLNFLVQEKEHPARY
                     RDHSLTASKHFQGVRECHTQPDWLLVYKVDKSELILNLLRTGSHSDLF"
     gene            90160..90312
                     /locus_tag="ACL3EZ_000375"
     CDS             90160..90312
                     /locus_tag="ACL3EZ_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0392009.1"
                     /translation="MKLRIFAEDKPAKKVFEYQLELADRTILLSTALLSGAIALAGIF
                     SALKEK"
     gene            90334..91575
                     /locus_tag="ACL3EZ_000376"
     CDS             90334..91575
                     /locus_tag="ACL3EZ_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000243957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HGR0392010.1"
                     /translation="MVLPNFKENLEKYAKLLVANGINVQPGHTLALSIDVEQRELAHL
                     IVKEAYALGAHEVIVQWTDDVINREKFLHAPMERLDNVPEYKIAEMNYLLENKASRLG
                     VRSSDPGALNGVDADKLSASAKAMGLAMKPMRIATQSNKVSWTVAAAAGLEWAKKVFP
                     NAASDEEAVDFLWDQIFKTCRVYEADPVKAWEEHAAILKSKADMLNKEQFSALHYTAP
                     GTDLTLGLPKNHVWESAGAVNAQGEEFLPNMPTEEVFTAPDFRRADGYVTSTKPLSYN
                     GNIIEGIKVTFKDGQIVDITAEKGDQVMKDLVFENAGARALGECALVPDPSPISQSGI
                     TFFNTLFDENASNHLAIGAAYATSVVDGAEMSEEELEAAGLNRSDVHVDFMIGSNQMD
                     IDGIREDGTRVPLFRNGNWAN"
     gene            91585..91815
                     /locus_tag="ACL3EZ_000377"
     CDS             91585..91815
                     /locus_tag="ACL3EZ_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000901571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HGR0392011.1"
                     /translation="MLGSMFVGLLVGFLAGAMTNRGERMGCFGKMFLGWIGAFLGHLL
                     FGTWGPVLSGTAIIPAILGAMIVLAIFWRRGS"
     gene            92083..92805
                     /locus_tag="ACL3EZ_000378"
     CDS             92083..92805
                     /locus_tag="ACL3EZ_000378"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HGR0392012.1"
                     /translation="MRLDKFLVACAVGSRTEVKNLLKAGRVTVNGKKEKSAKLQIDEK
                     IDEIRFDGQVLEYEEFVYYMMNKPKGVISATEDPKHRTVLDLLDDLARSKEVFPVGRL
                     DIDTHGLLLLTNNGQLAHVLLSPKRHVDKTYQAQVKGIMTQEDVETFIKGIPLKDFTC
                     QPARLEILSTDAEKNQSQIRVTIAEGKFHQIKRMVGYCGKEVVDLQRLTMGTLVLDEN
                     LERGEWRRLTKEELEILRANII"
BASE COUNT        27742 a        16985 c        20621 g        27463 t
ORIGIN      
        1 agaagatctg aaataactgt tatgatatag aggattgaaa ctagaatagt acacctctgc
       61 ttctaaaaca ttgttagaaa tcgatttgac tgtcctgatc gatttatcct gttcttattt
      121 catttcacta tagtaaggtg cagcaggata aagaaaaacc gagaagtttc tttctcggat
      181 ttgcttatta tgaggttcct attttctatg ctccaagagt tgattgatgt gatctacttt
      241 tttagcctct cttttataga gaatagccca gatgatgaga tagacaatcg caaactcgat
      301 aatgagctgg aggtagaaaa tccagtggaa agggaaccaa ccagcaagag ttgctagtgg
      361 gacaaagcca gccagcataa ggaagaaatg agtcagagtg gcacgaagca tgctccagtc
      421 acggctaaat aagcggttgc caaagttgaa gagcataccg atggttgccc agataagtgt
      481 gcagtagagc aagaccaggg caccgtgaac ctgatgctga tccatcactt ggcctatgag
      541 agagtaggga tttagtggtg cgtaggtatt tggtgcataa atgagtgaaa agaggataga
      601 gaggatgagg ccgataagaa caccggtagc tgcatcgtga aatacttgtt ttttcatagt
      661 tctaatttct ccttgatggt ttttagataa cggcgtgaag agtaggtgaa gctttcgttt
      721 ttcaagaaaa tttctaccag accgtttggc gtgagcttga ggtgagagat ggaatcgata
      781 ttgatgattt ctgattggga aatttggata aaattgcttg gcaagagttt aagaacctga
      841 tagagtcgca aatcaatgct gtaggtctga ctcgcggttt ctgctagaac cttccgattc
      901 tcgatataga agcgctgaat cttgccaatc tcaactagat agacctgatc atcgattttt
      961 cctttgattt tttctctttg gtccagattt tctgcgaact cgatgacttt ctggactttt
     1021 tcggtttctt gaggtgcttg gacaatcagc ttttcctcct cgtaagtctc actaatctgt
     1081 agttctactt tcataaattt ctctccttgt ttttcataca aaattaatct cacttcttgt
     1141 acacctttat taatactctt caaaaatctc ttcaaaccac gtcagcgtcg tcttgccgta
     1201 ggatagttgt tgactttgtc agttttatct acaacctcaa aacagtgttt tgagctgtct
     1261 gcgtctagct ttctagtttg ctctttgatt tttattgagt ataccactat tttactccct
     1321 ctggcaaggg actttgtcta tgtggaggga ttgggctcct atgtggtgga gtttttctgt
     1381 tctttctgaa atatggtata atagcactaa ttaatttcta ggaaaataga tacagaaagg
     1441 ggctgaaaga tgtctcatat tattgaattg ccagagatgc tggcaaacca aatcgcagct
     1501 ggggaggtca ttgaacgtcc tgccagtgtg gttaaagagt tggtagaaaa tgccattgac
     1561 gcgggctcta gtcagattat cattgagatt gaggaagctg gtctcaagaa ggttcaaatc
     1621 acggataacg gtcatggaat tgcccacgat gaggtggagt tggccctgcg tcgccatgcg
     1681 accagtaaga taaaaaatca agcagatctc tttcggattc ggacgcttgg ttttcgtggt
     1741 gaagccttgc cttctattgc gtctgttagt gtcttgactc tgttaacggc ggtggatggt
     1801 gctagtcatg gaaccaagtt agtcgcgcgt gggggtgaag ttgaggaagt catcccagcg
     1861 actagtcctg tgggaaccaa ggtttgtgtg gaggatctct ttttcaacac gcctgcccgt
     1921 ctcaagtata tgaagagcca gcaagcggag ttgtctcata tcattgatat tgtcaaccgt
     1981 ctgggcttgg cccatcctga gatttctttt agcttgatta gtgatggcaa ggaaatgacg
     2041 cggacagcag ggactggtca attgcgccaa gcaatcgcag ggatttacgg tttggtcagt
     2101 gccaagaaga tgattgaaat tgagaactct gacctagatt tcgaaatttc aggttttgtg
     2161 tctttacctg agttgactcg ggctaaccgc aattatatca gcctcttcat caatggccgt
     2221 tatatcaaga acttcctgct caatcgtgct attttggatg gtttcggaag caagcttatg
     2281 gttggacgtt ttccactggc tgtcattcac atccatatcg acccttatct agcggatgtc
     2341 aatgtgcatc caactaagca agaggtgcgg atttccaagg aaaaagaact gatgaccctg
     2401 gtttcagaag ctattgcaaa tagtctcaag gaacaaacct tgattccaga tgccttggaa
     2461 aatcttgcca aatcgaccgt gcgcaatcgt gagaaggtgg agcaaactat tctcccactc
     2521 aaagaaaata cgctctacta tgagaaaact gagccgtcaa gacctagtca aactgaagta
     2581 gctgattatc aggtagaatt gactgatgaa gggcaggatt tgaccctgtt tgccaaggaa
     2641 accttggacc gattgaccaa gccagcaaaa ctgcattttg cagagagaaa gcctgctaac
     2701 tacgaccagc tagaccatcc agagttagat cttgctagca tcgataaggc ttatgacaaa
     2761 ctggagcgag aagaagcatc cagcttccca gagttggagt ttttcggaca aatgcacggg
     2821 acttatctct ttgcccaagg gcgagatgga ctttacatca tagatcagca cgctgctcag
     2881 gaacgggtca agtacgagga gtaccgtgaa agcattggca atgttgacca gagtcagcag
     2941 caactcctag tgccctatat ctttgaattt cctgcggatg atgccctgcg tctcaaggaa
     3001 agaatgcctc tcttagagga agtgggcgtc tttctagcag agtacggaga aaatcaattt
     3061 attctacgtg aacatcctat ttggatggca gaagaagaga ttgaatcagg catctatgag
     3121 atgtgcgaca tgctcctttt gaccaaggaa gtttctatca agaaataccg agcagagctg
     3181 gctatcatga tgtcttgcaa gcgatctatc aaggccaatc atcgtattga tgatcattca
     3241 gctagacaac tcctctatca gctttctcaa tgtgacaatc cctataactg tcctcacgga
     3301 cgtcctgttt tggtgcattt taccaagtcg gatatggaaa agatgttccg acgtattcag
     3361 gaaaatcaca ccagtctccg tgagttgggg aaatattaaa agtataaaaa agtctgggaa
     3421 aaattttcaa aatcagaaaa acgcataaaa tcaggtgttc aaaaaccttg attttatgcg
     3481 ttttatcatg gaaatagtta cttcatgttt tcctaattct tttcgaaact ctttttaaac
     3541 cacgtcagtt ttatcagtaa tctcaaaaca gtgttttgag ctaattttgc cagttttgtc
     3601 tgtaacatcg aagttgtgtt ttaccactct gcgactggtt tcctagtttg ctctatgatt
     3661 ttcacagagt attaaattgc gattttgcca agtttcttta ttcgtctaaa agtagagtct
     3721 gttctatgcg tctaatgtac gaattaggtt gaccatttca atagctcctt gtgcacactc
     3781 agaaccctta tttcctgctt tggtaccagc tcgttctatg gcttgttcaa ttgtatctgt
     3841 cgttagcaca ccaaacataa caggaatttc gctatttaaa ctgatttggg cgattccctt
     3901 agatacctcg ctacatacat aatcataatg acttgtattc cctctaatga cagctcccaa
     3961 gcagataatt gcatcatatt ttttactttt tgccattttt gatgcaatca gtggtatttc
     4021 aaaagctcct ggaacccagg ctacctctat atctttctcg tttacattct ctcttttgag
     4081 attatctagt gctccagata ataattttga agttataaat tcattaaatc tcgctacaac
     4141 aatacctatt ttaatattgt ttgctactaa attaccttca taagtgttca tttatttttc
     4201 ctccatattt aaaatgtgac ccattcgatt tttctttgtt tctaaataaa aactatcgta
     4261 aggattggct tctatttcga ttgatattct actggaaatg gtaattccat atttttctaa
     4321 ctgttcaacc ttgtcaggat tatttgtcag taaatgaagt gactgaagtc ccagatcttt
     4381 aagcatttgt gctccaatat gatattctct taaatcacct tcaaagccta atgcaagatt
     4441 ggcatcaagc gtatccatgc cttgatcttg taaatgatag gcttttaatt tattgataag
     4501 tccaattcct cgtccctcct gtcgcaagta aagtaagaca cccgaaccat tctcaacaat
     4561 cattttcata gctttatcga attgctgtcc acaatcgcaa cgtaaagagc ctaaaacatc
     4621 tcctgttaaa cattcggagt ggacccgaca taatacattg gcttcatcct ctatgtttcc
     4681 cataataaga gcaagatgat gttccccatt tagtttatct atatagctaa ttgctttgaa
     4741 attaccgtat ctagtaggca tattgacagt tgaaactcgt tctatcagct gatcatatac
     4801 ttttctatat tcttgtaatt ctttgatggt aattagtgga atgttgtgtt tcttcgagaa
     4861 ctgaattaaa tcatctgttc tcatcatttt gccatcatga ttcattattt cacaacatag
     4921 gccacactct tttagtccag ctaattttaa taaatcaaca gttgcttctg tgtgtccatt
     4981 tctttctaga acaccacctt tttttgcaat taaaggaaac atgtgtcctg gcctgcgaaa
     5041 atcagagggt gttatatctt cagctacaca catacgtgcg gtcagtcctc tttcctcggc
     5101 agaaatacct gtggtcgttt ctttataatc aattgaaact gtaaaagcag tcttatgatt
     5161 atctgtattg ttttcaacca taggtgaaag cattaattga ttagctaaac tttcgctcat
     5221 aggcatacaa attaatcctt tggcataagt agccataaaa ttaacatttt ctgttgtagc
     5281 tgcttgtgca gaacaaatta agtctccttc attttctcta tccttgtcgt ctataacaag
     5341 aacaagtcgt cccttctgca atgcttctaa tgtttcttgt atttttcgat attccattga
     5401 ctgattatcc tttctgctaa aatccatttt gatataatag ttccttagat atttctgatt
     5461 ttggagagtt atccatcagt ttttgcacat atttacctaa gatatcattt tcaagattta
     5521 ctgtactccc gacttgttta cttttaagaa tggtttgttt caaggtatga gggataacag
     5581 atactgaaaa gtttactttg gagactttag cgacagtcag actaatgccg tcaattgtaa
     5641 tagatccttt ttcaactatt aaatctaaaa tttctttttg tgtgttgatt tgataccata
     5701 cagcattatc atcttttttt attgacgaga tttttcctgt accatcaatg tgtcctgtaa
     5761 cgacgtgacc cccaagtcga ccgttgatag ataaggctct ttctagattc acctcacttc
     5821 catgttttaa tagagtaaga gctgttcgac tccatgtttc attcattaca tcaactgtaa
     5881 aggattgatg attgaaatga gtaactgtaa gacagatacc atttactgct atactatcgc
     5941 ctaaatggat atccgttaat atttttgagg ctttaattga tagtttacaa ttacgagagt
     6001 ctttctgtat tctttcaact tttccgattt cttcaattat tcctgtgaac atggataaat
     6061 cacttcactt tctatgagat agtcatttcc tatttgagaa aaagcataag gtttcaatct
     6121 aatagcgtca tttggcaaag aaatgccttc acctccgaca ggaaacttgg cactgcctcc
     6181 aaaaattttt ggtgcaatat atattttcag ctcatcaaca atttgttgtt ccaaagcact
     6241 ccaattcatt agactgcccc cttctagaac taggctatca atctgcatgt ttcctagatg
     6301 ttgcattaaa ctcgataagt ctatatgatt gccttttttc tttatggaaa gtatttcaca
     6361 gccatgattt tgatatagct tcattttatt tttgtcttca gaggaagtgg caatgtaagt
     6421 tttaatatca tttgctgttt ttacgatttt agaggtaaga ggagttcgta aatgtgtatc
     6481 gcatatgata cggataggat ttttcccttc ctccaatcta catgtcagca aaggatcgtc
     6541 ttgaataaca gtattgactc ccaccataat tgcactaaca tggtgtcgta actgatgcac
     6601 atgctttctt gcttcttctt cagtaatcca tttggattga tttgttttag tggctatttt
     6661 tccatccatt gacattgcat atttcataaa aacatagggt acatgctggg taatatactt
     6721 tctaaaactt tttattaagt taagacactc attttctaaa attccaacag taacttgaag
     6781 attattttcc tcaagtatct ttactccttt tccagataca ataggattac agtctaggct
     6841 tccaatgact actcttgtaa taccactatc gattatagca tctatacagg gaggtgtttt
     6901 cccgaagtga caacagggtt caagtgttac ataaagcgtc gctccgacag gggattctct
     6961 acagttttta agagcatttc tctcagcatg tgggccacca aaaaactcat gataaccttg
     7021 tccgatgatg tgattatctt ttacaataac tgcgccgacc ataggattgg gattgacgta
     7081 accagcccct ttttgtgcca gttttattgc taatttcata tattttgaat cgctcatctc
     7141 actacctcca aaaaaaatat accttgaata ggggactact caaggcatac aaaagaaaac
     7201 ttatgcgatt aacaaaaata ctctgaaatg acaagtaatc atttcagagc acgcaaaaag
     7261 cacaaatata cttttatctt ctttcatcca gactatactg tcggctttgg aatttcacca
     7321 aatcatgcct ttcggctcgt gggctatacc accggtaggg aattacaccc tgccctgaag
     7381 atagttattc aattacagat gattatagta cttaattttg aatatgtcaa cagataaata
     7441 ccgattgttt ttgatatact gtatttgtga taatcgattc tcgctcctcg gataaagaaa
     7501 atatgatata ctagataaac gaaataagag agaaggaata ctatgtacgc atatttaaaa
     7561 ggaatcatta ccaaaattac tgccaaatac attgttcttg aaaccaatgg tattggttat
     7621 atcctgcatg tggccaatcc ttatgcctat tcaggtcagg ttaatcagga ggatcagatt
     7681 tatgtgcatc aggttgtgcg tgaggacgcc catttgcttt atggatttcg ctcagaggat
     7741 gagaaaaagc tctttcttag tctgatttcg gtctctggga ttggtcctgt atcagctctt
     7801 gctattatcg ctgctgatga caatgctggc ttggttcaag ccattgaaac caagaacatc
     7861 acctacttga ccaagttccc taaaattggc aagaaaacag cccagcagat ggtgctggac
     7921 ttggaaggca aggtagtagt tgcaggagat gaccttcctg ccaaggtcgc agtgcaagca
     7981 agtgctgaaa accaagaatt ggaagaagct atggaagcca tgttggctct gggctacaag
     8041 gcaacagagc tcaagaaaat caagaaattc tttgaaggaa cgacagatac agctgagaac
     8101 tatatcaagt cggcccttaa aatgttggtc aaataggagc agagaatgac aaaacgttgt
     8161 tcgtgggtca agatgacaaa cccgctctac atcgcctatc atgatgagga gtggggtcag
     8221 cccctccatg atgaccaagc attgtttgag ttgttgtgta tggaaaccta tcaggcaggc
     8281 ctgtcttggg aaacggtact caacaaacgc caagctttcc gagaagcctt tcatagctat
     8341 caaattcact cagtcgcaga gatgactgag actgaattgg aagccatgct ggagaatcca
     8401 gctatcattc gaaatagagc caagcttttt gctacacgcg ctaacgccca agtccttcta
     8461 cagttacagg cagagtacgg ctcttttgat gcctatcttt ggtcttttgt tgaggggaaa
     8521 attgtcgtta acgatgttcc tgattatcgc caagcgccag ctaaaacacc cttatctgag
     8581 aaattagcca aagatctcaa aaaacgaggc ttcaagttca caggcccagt cgccgtattg
     8641 tcttttctac aggctgcagg gctagttgat gaccacgaga atgattgtga gtggaaaggt
     8701 cttaaatgat gtctaacaaa aataagggaa ttctgatttt tgcgattctc tatacagtcc
     8761 tctttgtgtt tgatggcgtt aaattgctgg cttctttaat gccatctgtc attgcaaatt
     8821 atcttgttta tgtagtttta gctttatatg gctccttctt gttcaaggat agattgatcc
     8881 aacaatggaa ggagattaga aagactaaaa gaaaattctt ctttggcgtc ttaacaggat
     8941 ggctctttct cattctgatg actgttgtct ttgaatttgt atcagagatg ttgaagcagt
     9001 ttgtgggact agatggacaa ggtctaaatc agtctaatat tcaaagtacc tttcaagaac
     9061 aaccactact gatagctgtt tttgcttgtg tcattggacc tctggtagaa gaattatttt
     9121 tccgtcaggt cttattgcat tacttgcagg aacggttgcc aggtttacta agcattattc
     9181 tggtaggact tgtttttgct ctgactcata tgcacagttt ggctctatca gagtggattg
     9241 gtgcagttgg ttacttaggt ggaggccttg ccttttctat tatttatgtg aaagaaaaag
     9301 agaatatcta ctatccccta cttgttcaca tgttaagcaa cagcctctcc ttaatcattt
     9361 tagctatcag tatagtaaaa tgaaataaga acaggacaaa tcgatcagga cagtcaaatc
     9421 gatttctaac aatgttttag aagtagaggt gtactattct agtttcaatt tgctgtaata
     9481 tgtgatgaaa ataccagtaa tgataccgag aaaaaagctg agaaactttt cccagcttta
     9541 tttgttatag tcaaagcgaa tgacttgttc ctgtgcatct acatgagcat ggaccccaaa
     9601 gggtacaatt gctcttggag ttgcgtggcc gacattcaga ttatagacaa tcgggatatt
     9661 gctgtcaatg atatccaata gtgcctcttt atagtcgtca tggaaagttt catccatagg
     9721 ttttccgacc aagagtccat tgatgaccgc gaatatgcca gtgtccttta aagttagcaa
     9781 catctttttg aagtcttctg gcttaggctt ttcttcgctt gtttcgagca agaggatttt
     9841 cccttcccag tctgacaagt cagggaaaag tttgtatttt tggcagagtt ccgtgctatc
     9901 tgcgtatcga gagttgtcaa agatatcgta gagggattcg aggcaaccac cgaggatttt
     9961 tccctcgaac tgagcacttc cttgcaacaa gtcaaaacct gtatttgtat gactgacacg
    10021 aggtgttccc agggccgtgg gactaaaatc agttcgttcc tcataccaaa cgtcactagg
    10081 gcggatttct gaaattcttc ccgtcttaat caattcttta aagtagtgaa ggctataggc
    10141 tagcatttct ttgtctaatt cacaaatgtc tgctaaaaag gattgaccat aaaaagtctt
    10201 gattcctaat ttatgcaaca tgaggtggtt catggttgta tccgagaagc caagaaaaat
    10261 tttttgcttg ataacctttt ggagttggtc attttcaaaa agataaggta gcaagcgata
    10321 ggtatcgtct ccaccgatgg cacataggat catgtcgatg ctatcatcag aaaaggcatg
    10381 aatcaaatcc tctgcacgag cttcaggatg gtccttgata aagtctaatc cttttaacga
    10441 atgggacaaa aagatgggat tgagtcccag atccttgaga cgttggatac ccaagtccac
    10501 ttcgtgtttg acaaaatcct ctccgataat gccactagat aaactaacaa taccaatagt
    10561 agaaaccata tctcatcctc ctagaaatag attgagccta ttttatcaca aaatataaga
    10621 gaaagctatg tgggatttca gaagaatact tttaatactc ttcgaaaatc tcttcaaacc
    10681 acgtcagttt tatctgcaac ctcaaagctg tgctttgagc aacctgcagc tagcttccta
    10741 gtttgctctt tgattttcat tgaatataac tcaaaaaagt aagtgaaaaa gcaaccgcac
    10801 ctgcagttgc ttttatcgtt ttcttattct tgatagcgtg ttggtcctgc acttgcacta
    10861 cggatattca agcgtttctt gagatagaag cgaagggcta ggagggctgc tccaataata
    10921 gctagtggca atggatccag tactgggtta aggctagctg gtaggaagct tgttgcaaag
    10981 aagacaagca accaaaggaa catagaagct aggataacta gtacagattt ccagaaaggt
    11041 ggacgttgac tgcgatccat atctgatcca tagtattggt aaacaaagta gtacatcaag
    11101 tagaaggcaa atccaccaac cagtccaact aatagaagag taatcaatcc atagccgaaa
    11161 gcttggtctg ccgcaaagaa ggttgtgagg gcgctgacaa gggcaaagag gctagtgatg
    11221 aaaagagctg agtccataat catcagtttt gggtcatcat tttcttttgg atgctctttt
    11281 tcgtactgct ctttgacagt gaagctatga gcccaatgag ttggtgcgcc gtatagggaa
    11341 cgggcagttg tacctttaga ttgctcctca aggatttggg gaatgacttc ctcaaaaata
    11401 gtctggattt cagcgtctgt tttcccatct ttgatgaatt gttgggtagc aatgtggaca
    11461 aactcttggt ttttcttagt taatttttgt agatcaattt gagacatagg aactcctctt
    11521 agaaccattt tttatggatg agatagagag tgagcgagac actcatagca aaggcgataa
    11581 agacgattaa ccagaaggca tttggctctc cgtttagggg gatttcatta tccttaaagt
    11641 tcatcccgta ggcagaaaag accatggttg ggatggacat gacgatggtc acaagggcca
    11701 aggttttcat gatgttgttc tggttgttag aaatgataga ggcaaaggtc tctgtcatag
    11761 aatgcaagac gtttccataa atatctgcca tctcgatggc ctgttgggtt tcaatcaggg
    11821 tgtcttcaag caggtcttcg tcctcaaggt atttcttgat attgctggtt gaactggtca
    11881 atttcttaat cacgcgctca tttgttttga gggaggcctt gaaatagacg atagtttttt
    11941 ccaattccat gagctcaatc aattcttcat tacgagttga ttgatgcagt tgactttcga
    12001 tttgttcact cttgcggtcg attgaacgaa gggctgttag gtaaagctct gcattgcgat
    12061 aaagaatttg aaagataaaa cgtgaacgca tgaaggtata gaaattacgc aatcgacggt
    12121 tgataaagac atcaaggaca ggtagtggtt ccaaacacgt agtgataatg gtttcctcag
    12181 tgatgataat accaagcggg atggttacgt agtaggtgcg gttatttctt tcctccgtga
    12241 ccggcacgtc tacgataatc agggtatact cgtcttcaat ggtaatacga gacatttctt
    12301 ccgcatcgag cggtgctcga aggtcggcaa tatcaatatc gaaggtgttg gcgatttcga
    12361 gtgattcatt ttgagtcgga ttgacgagat tgatccaagt acccggttca agcgtatcga
    12421 tctctttaaa ttcagttgtt gtagagagaa aaacttgttt catatccctt atcctttctc
    12481 atttttcaga ttttttcaca ctgtactatt atactacaaa atcggccttt tgggtaatag
    12541 aatctcactt tttttggtat aatggtaagc aataatggac tagaaagaac aaagatgcaa
    12601 gataaaattg tcattcatgg ggcgcgtgcc cataatttaa aaaatattga tgtggagatt
    12661 ccgcgagaca agttggttgt cgtgactggc ttgtcaggtt cagggaagtc cagtctggct
    12721 tttgatactc tctatgcgga gggacaacgt cgctatgtag agagtttgtc tgcctacgct
    12781 cgtcagttct tgggaaatat ggaaaaacca gatgtagatg ccattgatgg tctcagccca
    12841 gctatttcca tcgaccagaa aacgactagt aaaaatcctc gctcgacggt gggaacgacg
    12901 actgaaatca atgactatct gcgtctcctc tacgcacgtg tggggacgcc ttactgtatc
    12961 aacggacatg gagctatcaa tgcttcttct gtggagcaaa tcgttgataa ggttttggag
    13021 ttacctgaac gccagcgctt gcagatcttg gctcctgtca tccgcaagaa aaaaggccaa
    13081 cataagagtg ttatcgagaa ggttcagaaa gacgggtatg ttcgtgttcg tgtggatggg
    13141 gaagtctatg atgtgaccga agtgccagag ttgtctaaga gcaagcaaca caatatcgat
    13201 gtcgtggttg accgtattgt tatcaaggag ggcattcgta gccgtctctt tgattccatt
    13261 gaagctgccc ttcgtatcgc agaaggttat gtgattatcg acaccatgga cgactctgag
    13321 ttgttgttct ctgagcatta tgcctgtcca gtttgtggat ttactgtccc agagttagaa
    13381 cctcgtctct tctctttcaa tgctcccttt ggctcttgta gtgagtgtga cggcttgggg
    13441 attaagctgg aggtggatac tgatttggta gtgccagatg ccagcaaaac cttacatgag
    13501 ggagcgctgg caccttggaa tcctatctca tccaactact atccaaacat gttagagcag
    13561 gccatgaaag tctttggagt ggctatggat aagccttttg aggacctgtc agaagaagat
    13621 aagaacttga ttctctacgg ctcagatggt aaggaattcc atttccatta tgaaaatgaa
    13681 tttggtggtg tgcgcgatat cgacattccg tttgagggag ttatcaataa tatcaaacgt
    13741 cgttaccatg aaaccaatag cgattacact cgcactcaga tgcgtctcta catgaatgag
    13801 ctgacctgcg gaacctgtca aggctatcgt ctcaatgacc aggccttgtc tgtccgtgtg
    13861 ggcggccagc aagggccaca tattggagaa atctcagacc tgtctatcgc tgaccacttg
    13921 gacttggtga gccagttaac tttgtctgaa aatgaagcca tcattgctcg tcccattctc
    13981 aaggaaatca aggatcgttt gaccttcctt aataatgtgg gtcttaacta tctaaccctg
    14041 tcacgttcag caggaaccct ttcaggtggg gaaagtcagc gcattcgttt ggcaacccag
    14101 attggttcca acctatcagg tgtcctctat atcctagacg agccgtcaat cggtcttcac
    14161 cagagggaca atgaccgcct gattgccagt ctgaaaaaga tgcgtgactt gggcaatact
    14221 cttatcgtgg tggaacacga cgaagatacc atgcgtgaag ctgattatct gattgacgtt
    14281 ggtcctggtg ccggtgtttt tggtggtgag attgttgcag caggtacacc taagcaagtg
    14341 gctcgcaaca gcaagtctat cacaggtcag tacttgtcag gcaaacgtgt catcccagta
    14401 ccagaagagc gccgtgtcgg aaatggtcgt tttattgaag tgacaggagc gcgtgagaac
    14461 aacttgcaaa atgtcacggc tcgctttcca ctaggaaaat ttatcgcagt gacaggtgtg
    14521 tcgggttcag ggaaatcgac tctaatcaac agcattctca aaaaagccat tgcccagaag
    14581 ctcaaccgta attcagacaa acctggtaag tttaagacta ttacagggat tgagcatgtc
    14641 gaccgtttga ttgatattga ccagagccct atcggacgga cgccgaggtc taacccagct
    14701 acctatacag gagtttttga cgatatacgt gacctttttg ctcagacaaa tgaagccaag
    14761 attcgaggct acaagaaggg gcgcttcagt ttcaacgtca agggaggtcg ctgtgaagct
    14821 tgctcaggtg acgggattat caagattgag atgcacttct tgccagatgt ttatgtggct
    14881 tgtgaagttt gccacggaac ccgctataac agtgaaaccc tagaagttca ctacaaggaa
    14941 aagaatattt cgcaggtctt ggatatgacg gtcaacgatg cggtagaatt tttccaacac
    15001 attccgaaaa ttcaacgcaa actccagacc atcaaggatg taggtctagg ctatgtgacc
    15061 ttgggacagc cagctaccac cctttctggg ggagaagccc aacgtatgaa gttagctagc
    15121 gaactccaca aacgctcgac aggaaaatct ttctacattc tggatgagcc gacgacaggg
    15181 cttcatacag aggacattgc tcgcctgctc aaggttttag ctcgctttgt agacgccggc
    15241 aatacagtcc tcgtcatcga gcacaatctg gatgttatca agacggcaga ccatatcatt
    15301 gacttgggac ctgagggcgg tgtcggtggt ggaaccatca tcgtaacagg aactccagaa
    15361 gaagtagctg ccaacgaagc cagctataca ggacactatt tgaaaggaaa gttacatcat
    15421 gaataaacgc gtacaagcat ttctagctaa aatgcaagaa aaagaactag atggtatcat
    15481 catcaacaat cttaaaaacg tctattattt gactggtttt tggggctcaa acggaacagt
    15541 ctttatcagc cgtgaccgtc aggtcttagt gacagactct cgctatatca tcgcagctaa
    15601 gcaagaaacc agtggttttg agattgtggc tgatcgtgat gaattggctg tcattgcagg
    15661 aattgttaag gacatgaact tgactcgtat cggttttgaa gatgagattt cagtgtctta
    15721 ttaccaccgt atgcaggcag cttttgcagg tttgaacttg cttccacaaa ctcagtttgt
    15781 ggaaggtctt cgtatgatta aggatgaggc agagattgca gcgattcgca aggcttgttc
    15841 tatctcagac caagctttcc gcgatgcgct tgactttatc aaaccaggaa aaactgaaat
    15901 tgagattgcc aacttccttg atttccgcat gcgtgagttg ggagcatctg gcttatcttt
    15961 tgatacgatc ctagctagcg gtatcaattc ttctaaaccc catgcccatc caatgcacaa
    16021 accagtggag ttgggagaag ccattaccat ggacttcggc tgtctctatg accactatgt
    16081 cagtgatatg acccggacta tctatctagg gcatgttagc gatgagcagg cagagattta
    16141 caatacggtt ctaaaagcta accaagcctt gattgaccaa gctaaggcag gcttaggttt
    16201 ccgtgacttt gacaaaatcc ctcgtgatat tatcattgag gcaggttatg gtgactactt
    16261 tactcacggc attggccacg gtattggtct ggatatccat gaggaaccct actttagtca
    16321 gacttctaca gaaactatta agacaggtat ggccttgacc gatgaaccag gtatctatat
    16381 cgaaggcaaa tatggcgttc gtatcgagga tgatatcctg attacagaga caggttgtga
    16441 attattgacc ctagctccaa aagagttgat agtcatttag ttgtttgtca agaaaaaagt
    16501 acgaaaatga cgaaaaaagt caaaaaaaat taaaaatagg tcgcaagtcg gatgtttttt
    16561 atggtataat agactaaact gatagtaaca tgtagcgaaa ggggtaggta catgattaaa
    16621 atttatacag tctcaagttg tactagttgt aaaaaagcaa aaacctggct caatgcccac
    16681 cagttaagtt ataaagaaca aaaccttggt aaagaaggaa ttacgagaga agaattactg
    16741 gatattctaa ccaaaacaga taacggaata gccagcatcg tttcgtctaa aaatcgctat
    16801 gccaaagccc ttggagtgga tattgaagat ttgagtgtca atgaagttct caatctgatt
    16861 atggaaacac cgagaatttt aaagagccca atccttgtag atgaaaaacg cctgcaagtt
    16921 ggctacaagg aagacgatat tcgtgccttc ctaccacgct ctgtccgtaa tgtagaaaat
    16981 gcagaagcac gtttgcgtgc agctctataa acatcaaggc tgggagcact tcccagtctt
    17041 attctatttt aatttcaaaa agaaagaaga aagaaatgaa aaaaatagtt cttgttagtc
    17101 tagctttcct ttttgtcctg gttggttgcg gacagaaaaa agaaactgga ccagctacaa
    17161 aaacagaaaa agatacgctt cagtcggcat tgccagttat tgaaaatgct gagaagaata
    17221 cagttgtaac taagactttg gtcttgccca agtcagatga tggtagccag cagacacaaa
    17281 caattactta caaagacaag acttttttga gtctagctat ccaacaaaaa cgtccagtct
    17341 ctgatgagtt gaagacttat attgaccaac atggagtgga ggaaactcaa aaagctcttc
    17401 ttgaagcgga ggagaaggat aagtctatca ttgaagctcg taaattggca ggtttcaaac
    17461 ttgaaacaaa actattgagc gcaacggaac ttcaaacaac gactagtttt gattttcaag
    17521 ttctggatgt caagaaggct tcccagttgg aacatctgaa gaatattggt ttggaaaatc
    17581 ttttgaaaaa tgaaccaagc aaatatattt cagatagatt ggcaaatggc gcgacagaac
    17641 aatagaaaat ccaaataaat agactgcctg aattgtagaa ggtaaggaat tatgctataa
    17701 tggtactatt ctaaggaaag agggtgttag aatgggattt actgaagaaa cagtacgttt
    17761 taaattggac gattccaata aaaaagaaat tagcgaaact ttgacagatg tttatgcttc
    17821 gttgaacgat aagggttaca acccaattaa ccaaatcgta ggttacgtat tgagtggaga
    17881 ccctgcctac gttcctcgtt ataataatgc acgaaatcaa atccgtaagt atgagcgtga
    17941 tgaaatcgtt gaggaattgg ttcgctacta cctcaaagga caaggagtcg atctataacc
    18001 tatgagaatt atgggattgg acgtcggttc aaaaacggta ggggtggcga ttagcgatcc
    18061 gcttggtttt acagctcaag ggcttgaaat catccagata aatgaagaac aaggccaatt
    18121 tggttttgac cgcgttaagg aattggttga tacttacaag gtggaacgat ttgtagtggg
    18181 cttgcctaaa aacatgaaca atacaagtgg accgcgcgta gaagctagtc aagcctacgg
    18241 agcaaagcta gaagagtttt ttggtttacc agtagactat caggatgaac gcttgacaac
    18301 agtggctgct gagcgcatgt tgattgaaca agcagatatc agtcgcaata agcgcaagaa
    18361 agtcattgat aagttagcag ctcagctgat tttacaaaat tatttagata gaaaatttta
    18421 atataaagga gaggctatgt cacacgatca taaccacgac cacgaagaac gtgaactaat
    18481 cacactagta gatgagcaag gaaatgaaac cttgtttgaa atccttttga caattgatgg
    18541 aaaagaagaa tttggtaaaa actatgttct tctagtacca gttaacgcag aagaagacga
    18601 agacggacaa gttgaaatcc aagcttactc attcattgaa aatgaagatg gaacagaagg
    18661 cgaattgcaa ccaatcccag aagactcaga agacgaatgg aacatgattg aagaagtctt
    18721 caacagcttt atggaggagt gatacagtct gggagactgt atcagcccaa ctccagaaat
    18781 ggggaagagt tggaacgtcc agtgaacatt tttaccccaa ctcttagaaa ttgagaagag
    18841 ttggaacatc tagtggatgt ttttagccca tattcacatt catagtagct agttattagc
    18901 taaccaggta agaggtcggg acgaaaatcc tggccttgtt tttattagta accatacttt
    18961 aatgcgataa ttgattggac ttttgtcaag gagatgtgta tgtttgaagt agaagaatgg
    19021 ctccatagtc ggattggttt gaattttcga tcaggtttgg gccgaatgca gcaagcggtg
    19081 gatttgttag gaaatcctga gcagtcttac cctattatcc acgtaacagg gactaatggg
    19141 aaaggatcta ccattgcttt tatgagggaa ttatttatgg ggcatggcaa aaaagttgcg
    19201 acctttacct cccctcatat cgtctctatc aatgaccgaa tctgcattaa tgggcaacct
    19261 atagcagacg cagactttat ccgtttgact gatcaggtca aggagatgga gaaaacgctt
    19321 ctgcaaactc ctgcccagtt gtcctttttt gaattgctga ccttagttgc ttttctttat
    19381 tttagggagc aagaggtgga tttggtttta ttagaagtgg gaattggtgg cttacttgac
    19441 acgaccaatg tggtaactgg agagcttgct gtcatcacct ccattgggct tgaccatcaa
    19501 gaaaccttgg gtgatagtct agaagcaatt gcagagcaga aagctggtat tttcaaggct
    19561 ggtaaaaagg cagtgattgc gaaattgcct ccagaagcta gacttgtctg tcagaaaaaa
    19621 gccgaatctt tagctgttga cctttatcag gcaggtcaag atttttcagt gctgaatggt
    19681 gatttttcaa gctctttact aaatctttca cagctgaaca taggcttaga aggagcctat
    19741 cagcaggaga atgcggcctt ggcgttgcaa acttttcttc tttttatggg agaaagaaag
    19801 gaagctattg atgaacaggc tgtaagaaag gccttggaac agacccattg ggctggtcgc
    19861 ttggagcgta ttcgcccaca gatttacttg gatggtgctc ataacctccc tgccttgact
    19921 cgcttggttg agtttatcaa agaaaaagag caggaaggct atcgacctca aatcctcttt
    19981 ggatccttga aacgtaagga ttatcaaggg atgttgggtt atctgactga aaatttacct
    20041 caagtggaac tcaaaatgac cggctttgac tatcaagggt ctttggacga gacagatgta
    20101 acaggttacc atgtaattcc ctcttaccga gaatttatca gcagtttcga agaaagggca
    20161 gacgctcaag acttgctgtt cgttacaggg tctctctatt ttatctcaga agtacggggc
    20221 tacctgctgg accgtgagca gataaattga cccccttttt tgaacttgtt atactagggg
    20281 aattgctggt tagagaaaat ttctctaaat tggtagcaga aaggaaattc atcatgaaat
    20341 taaaaagatt cacactttct cttgcttctc tagcaagttt tagtctctta gtagcttgtt
    20401 cacaaagagc tcaacaggtt caacagcctg ttgctcagca ggtccaacag cctgctcaac
    20461 agaataccaa tactgcaaat gcaggaggta accaaaatca agcggctcca gtacaaaacc
    20521 aacctgttgc tcaaccgacc gatattgatg ggacttatac tggtcaggat gacggagacc
    20581 gtatcacttt agtggtaact ggaacgactg gtacatggac tgagctcgaa tctgacgggg
    20641 atcagaaagt caaacaggtt acatttgatt cagcaaatca acgcatgatt attggcgatg
    20701 atgtcaaaat ttacactgta aacggtaatc aaatcgtcgt agatgatatg gatagagacc
    20761 catcggacca aatcgtttta actaaataag actatgcaag tagaaagggc tggatttttc
    20821 agccttttta cttttaccta gaaaataatc ataaatactt gccttctacc gaatacctgc
    20881 gttatactag tatcaattac ttgtttttag cattcaaact atcaaggagg ggatatgaaa
    20941 tataggaaat ttcaattatt gatgtccaag tatggcttta gtctttcgat tatgctactt
    21001 gaactttgtc ttgtttttgg tctctttctt tatttaggac gcatggctcc cattttatgg
    21061 attactgtcc tcattctact gagtatcatc acaatcattt cgatagtcaa ccgtaatacg
    21121 actcctgaga ataaggtaac ctggttgtta gtagcctttg tgccagtatt tggtcccttg
    21181 ctctatctga tgtttggtga aaggcgattg tccaaaaaag aaatcaaaca actgaagaag
    21241 ctaggctcta tgcatttcca agaagcaaat agccagctac taaaagagaa attaaaagaa
    21301 agtgacaagg cagcttatgg agtcatcaag tccttattga gtatggatac caatgctgac
    21361 atctatgatc aaactgcctc tacatttttt cctaacggag aagctatgtg gaaaaagatg
    21421 gtagaagatc ttaaaaaggc tgagaaattt attttcttgg aatattacat tatagaagaa
    21481 ggtttgatgt ggaatcgcat actagatata ctagagcaaa aggtagctca gggtgtagag
    21541 gttaagatgc tctatgatga tatcggctgt atggctactt taacaggaga ttatgcacat
    21601 cgacttcgtc agctgggcat cgaggcccat aaattcaata aagttattcc tcgtttgaca
    21661 gtggcttata ataacagaga tcatagaaaa atattgattg ttgatggtca gatagcctat
    21721 actggtgggg tcaatctggc agatgagtac attaaccacg tcgagagatt tggttattgg
    21781 aaggatagtg gaattcgctt agacggacta gcagtaaaag ccctgacacg cttatttttg
    21841 accacttggt acattaatcg aggagaaatt agtgattttg atcaatatca tttagaaaat
    21901 cattctatcc cgagtgacgg tttaaccatt ccatacggaa gtggacccaa gccaattttt
    21961 cgagcgcagg tagggaaaaa agtttatcag agtttaatca atcaagcaac agaatcggtc
    22021 tatattacga caccttattt gattatagat tatgatttaa cagagacaat caaaaatgca
    22081 gctatgagag gggtcgatgt tcgaattatc accccttaca taccagataa gaagttcatt
    22141 cagttagtca cgagaggagc ttatcccgac cttctttctg ctggtgttcg gatttatgag
    22201 tatagtccag gttttattca tagtaagcag atgttggtag acgaagattt tgcggtggtg
    22261 gggacaatca atctcgacta ccggagcttg gtacaccatt atgaaaatgc agtcttactc
    22321 tataaaactc cttctataag ggaaatcgcc cgagattttc gaaatatatt tgcagattct
    22381 caggaagtct atcctcattc tatcaaaacg agctggtatc aaaagcttgt aaaagaaatc
    22441 gcccagctat tcgcccctat cttataagaa atctagaact taggatacaa accagaccta
    22501 tttttcttgt cttttactaa tagaaagaaa gaggagggga attcatgcta actaaggaag
    22561 aagtgaatga tatgattgag ttcaaacaga cacatttaca ccgctttcgg gaaattgaaa
    22621 cctttgtgaa actatgcaaa aaatcactca aacagccatc gcaagctgac aatcctagga
    22681 ctttttgata tactaagaca gataaattga acaggagaaa cgatatgagt gtgtatggta
    22741 gagtagaaga agttcataag gagaatcgtg aacctctaga ataccaaatc gaacaagaat
    22801 cgcatcatcg tgaatcaagt cgtcttcctt tggtgaaaat tttactatgg agtacgcttg
    22861 taacggggat aactctagga gtaccgctat tactcgactt aatgagtgca caagaagtgc
    22921 aggattttta tgcaggttgg gggcttcatc agacagggaa gatttacagc gactattatg
    22981 gaagtcaagg tttgctttat tatttgctga cttacgtgag tcagggcgga tttttctttg
    23041 ccatctttga gtggttagcc ttggtagcag gaggattttt cctttttaga tcagcggaca
    23101 ccttgacaga gcaaggagac caagctggac atctggtgac tattttttac atgctagtta
    23161 caggtcttgc ttttggtgga ggctatgcga ctcttttagc gcttcctttc ttattcgcag
    23221 cctttagttt agttgcggct tacctaagca atccaagcca tgataaggga tttgtacgga
    23281 ttgggctagc tttggcaggc ggatttttct ttgctccctt atcatcgctc ctgtttattg
    23341 ctgtagtgag tttaggcttg ttggtcttta accttgggca tagacgcttt gcgcatgggt
    23401 tttatcagtt tcttgcagtg gctttaggtt tttcacttgt cttttatcca actgcctact
    23461 atagtgctgc aacaggaagt tttggggatg cgattagtgg tattcgttat cctattgaca
    23521 gtattcgctt tgattttact tctaaaattt tagagaatat gtttttttat ggcttgttgt
    23581 cccttggttt gggatttgtg gtttgtatct ttttaggtct ctttcaatcc aaacccttta
    23641 aactatacgt catttcggtt cctgcaagtc ttgtggtaat tttaggtttg attttacttt
    23701 tcttttcaca agagcctctg cacgcttctt atttgatggt cgtcttccct gttttcctac
    23761 ttttattggt aaccaatatt aagagtcaac agagggggcg tagtgctaga agaagccgaa
    23821 gagaaacgcc agttagccta tggagtcgtt tcttcaaagg aaatctatat ctgctagttt
    23881 ttgggtttgt ctatcttttg tctgttcctt ttttgatgaa gtttgtcctt tatccagtac
    23941 cttatcaaga acgtaatcgt cttgctgatt tggtaaaaga ggagacaaat acggaagatg
    24001 ctatctatgc atgggatgat actgcgactc tttatcgtaa gagtgagcgc ttgtcgccat
    24061 cggcgatttt gtccccgttg cactatacag caactgagga aaatcgtaat aagttactta
    24121 atgacttgaa agaaaaacaa cctaaggtga ttgtggtaaa tgacaaggtg gtagtctggt
    24181 ctgaagtgga aacactttta aaagaaaatt accaacaagt aaagactgat tactcagagt
    24241 ttaaagtcta taaaattaaa taaccaaatc aatatcttgt gtatttttaa aaattttagg
    24301 atttttaaca caagatattg atttttcttt ttagagtggt ataatacttt ttagaaagaa
    24361 cattttagaa aagagcatgc gtatgattgc actagaagaa aaaattacaa ttttgccaac
    24421 tctcttcgtc gagaaacgag atgggagacg tgttgtattt gatgtggaca agattgacaa
    24481 ggctctccac aaggcggctg acaaggttat ggatgtgaca cccctggttg aaaaacgcct
    24541 caatgatctg actgagcgaa ttattacaga aattcatagt cgctttccac agggaattaa
    24601 gatttacgaa attcaaaata tcgtagaaca tgaactcctt gaagccaaag aatatgcgct
    24661 ggctgaggag tatattactt atcggacaca gagggatttt gagcgctcaa aagcgacgga
    24721 tatcaacttt agtattcata aacttctcaa caaagaccag acagttgtca atgaaaatgc
    24781 taataaagac agtgatgtct ttaacactca gcgtgatttg acagcaggga ttgttgggaa
    24841 atcaatcgga ctgcaaatgc ttcctaagca cgtagccaat gcccaccaaa agggggatat
    24901 ccactatcac gatttggact acagtcccta tacccctatg accaactgct gtttgattga
    24961 ttttaagggt atgttggaaa atggttttaa gattggaaat gcagaggtag agagtcccaa
    25021 gtctatccag actgcgacag cacagatttc tcaaatcatt gccaacgttg cttctagcca
    25081 gtacggtggc tgttcagctg accgtatcga tgaaattttg gcgccttatg cagagaagaa
    25141 ttatcaaaaa catctcaaag atgcagaaga gtgggtattg cctgaaaaac gggaagatta
    25201 cgcttggaag aaaacgcaaa aggacatcta cgatgccatg caatctcttg agtatgaaat
    25261 caatactctc ttcacttcaa atggacaaac accttttact tcgttaggtt ttggtctggg
    25321 aaccagtcgt tttgaacgag aaattcaaaa agctatttta aacattcgca ccaagggtct
    25381 tggttcagaa caccgtacgg ctatctttcc taaacttatt ttcactctga aaagaggcct
    25441 taatttagag gaaggaactc ccaactacga catcaagcag ttggctcttg agtgtgcaac
    25501 caaacggatg tatccagatg ttttatctta cgataagatt gttgacttga caggatcctt
    25561 caaggtgcct atgggttgcc gttctttcct ccaaggatgg aaggatgaaa atggtgtaga
    25621 agtcaattca ggtcgcatga atctgggtgt tgtgacggtt aatctgcctc gtattgctct
    25681 tgagtctgaa ggtgatatga ataagttctg ggaaatcttc aacgagcgaa tgaatatcgc
    25741 agaagatgct cttgtttacc gtgtcgaacg cactaaagag gcgacaccag caaatgctcc
    25801 tattctttat cagtacggtg cttttggcca tcgtctaggt aaagaagaaa gtgttgacca
    25861 gctctttaag aatcgtcgtg ctaccgtttc gctgggctat atcggcttgt atgaagtagc
    25921 gacagttttc tttggtaaca gctgggaaag taatccagat gctaaggaat tcacgctaga
    25981 catcattcac gatatgaaac gccgtgtaga agagtggtca gaccaatatg gctaccattt
    26041 ctctatctac tcaacaccat ccgaaagtct gacagaccgt ttctgtcgac tagatataga
    26101 caagtttggc tctattcctg atatcacaga caaggaatac tacaccaact ctttccacta
    26161 cgatgttcgt aaaaatccaa caccgtttga aaaattggac tttgagaaag tctatccaga
    26221 agcaggtgcg tcaggtggtt tcatccatta ttgtgagtat ccagtccttc agcaaaatcc
    26281 aaaggccttg gaagctgtct gggattatgc ttatgaccgt gtaggctatc taggcaccaa
    26341 tactccgatt gaccgttgct acaagtgtga ctttgaaggg gattttgaac caactgagag
    26401 agggtttgct tgtccaaact gtggcaatag cgaccctaaa acagtagatg tggtgaagcg
    26461 aacttgtggc tacctaggta atcctcaagc aagaccgatg gtcaacggcc gtcacaagga
    26521 aatcgctgcg cgtgtcaaac atatgaatgg ttcaacgatt aaaatagctg ggcatcaagt
    26581 aacaaattag aaagaaatga aatgggaaaa tatcaactag acgataaggg gcgcgcacaa
    26641 gtgacccgtt atcacgagaa acactctaaa ggtggagctg gtaagaaaga acgcttgctt
    26701 agcttcagag aacaattttt aaacaagaac aagaaaaaat aaaagtgaga gccagctctc
    26761 gcttttctca tagtgggagg taaggatgga attacgcaga ccaagattag cggataagaa
    26821 agctgtttta gatatgatga cagagtttga aaagagccaa tcagcccatg atggaggatt
    26881 ttgggataca gagaattttg tgtatgaaga gtggttggaa agcaatcagg aacaggaaat
    26941 ggggattaat ctgcctgaag gatgggttcc tgcaattcag ttagtggctt tttctgagaa
    27001 aggtcaagca gttggatttc ttaatctccg gttgcgcctc agtaactttt tactagaaga
    27061 aggtgggcac attggctact ccatccgtcc atctgaaaga ggcaagggtt atgcaaaaga
    27121 gactctccgt cagggcttgc aagttgctaa ggaaaagaac atcaagaaag ctctggtgac
    27181 ctgtagcgtg aataatcctg ctagtagagc agtcattcta gcaaatggtg gaatatttga
    27241 ggatgctcac aatggagtcg agcgttattg gatagaggta gcgaatgaat aatccaaaac
    27301 cacaagaatg gaaaagcgag gaacttagtc aaggtcgtat cattgactac aaggccttta
    27361 actttgtgga cggcgaaggc gtgcgtaact ctctctatgt atcaggctgt atgtttcact
    27421 gcgagggatg ttataatgtt gcgacttggt cttttaatgc tggcattccc tatacagcag
    27481 aattagaaga gcagatcatg gcagatcttg ctcagcccta tgttcaaggt ttgactttgt
    27541 tgggagggga gccttttctt aatactggga ttctcttgcc acttgttaag cggattcgga
    27601 aggaattgcc agacaaggac atctggtcct ggaccggcta cacttgggaa gaaatgatgt
    27661 tggaaactcc agataaactg gaattcttgt cactgattga cattcttgtc gatggaagat
    27721 atgatcgaac taagagaaat cttatgctcc agtttcgagg ttcatctaac caacgaatta
    27781 tcgatgtgca aaaatcgctc aaaagtgggc aagtagtgat ttgggacaag ctcaatgacg
    27841 gaaaagaaag ctatgaacag gtgaagagag aatgaagaaa aaagacttag tagaccaact
    27901 agtctcagag atcgagacgg ggaaagtcag gacactggga atatacggtc atggagcttc
    27961 aggtaaatca acctttgcac aggaattgta ccaagcttta gattctacta cagtaaattt
    28021 gctagaaaca gatccctata tcacctccgg acgctatttg gtagtaccca aggacgcgcc
    28081 gaatcaaaag gtgacagcca gtctgccagt ggcgcatgaa ctggagagtt tgcagagaga
    28141 tatccttgcc ttgcaggcgg gtatggatgt cttgacaatt gaagaacctt ggaaggctag
    28201 tgaggtcttg tctggagcca aaccaatttt gattgtcgaa gggatgtctg ttggttttct
    28261 acccaaggaa ctctttgaaa aaaccatctg tttctacacg gatgaggaga ccgaattaaa
    28321 gcgacgcctt gctagagata cgactgtgag aaatcgcgat gcatccttta tattggctag
    28381 ccatcagatg agacgggagc agtatctgcg atactataaa gaaactgagt ctaaggcgga
    28441 tatcttagtg gaccaatcag aagataaatt tgatgtcaag aggacttaac ttatgtatag
    28501 aagaaatata gaagaaaatc cctaatttta gaaagaaaaa gtaggaaaac agtttcatcc
    28561 caaaaaaacg aaaaaaccta acaaatccct tgcaatcgca ggggatttgt gttattctat
    28621 tatggtgctg taaattacag ccttagtttt gatgcaagag gttgcgacac gctcggttgc
    28681 attgccacgc aacaccgcgt cggttttctt gtggagctag cctattatct taaatagacg
    28741 aaaaggagaa aaagatggca aacaaaaaaa tccgtatccg tttgaaagct tacgaacacc
    28801 gtacgcttga cacagcggct gcaaaaatcg tagaatcagc tactcgtaca ggtgcacaag
    28861 ttgcgggtcc aatcccactt ccaactgaac gtagcctcta cacaatcatt cgtgcgactc
    28921 acaaatacaa agactctcgc gaacaatttg aaatgcgtac acacaaacgt ttgatcgata
    28981 tcgttaaccc aactcaaaaa acagttgatg ccttgatgaa attggatctt ccaagtggtg
    29041 taaacgtaga aatcaaactt taatctaaaa tataaaagag cagaggctgg tgtttcaatc
    29101 taattgaaca cgggctagac tcggtgtgaa aaagataaac ttcctattgt ccgctagaca
    29161 ctgcgttagt ttcctatttt cactttgagt ttgacgccct ttgtatctta gacttgagca
    29221 taaaaaacgc tcgttaaaaa ctttttgaat aaaaaatata gaaaaggaac tattttctca
    29281 tgacaaaagg aatcttaggg aaaaaagtgg gaatgactca aatcttcact gaagctggcg
    29341 aattgatccc tgtaacagtt attgaagcaa ctccaaacgt tgttcttcaa gttaaaactg
    29401 ttgaaacaga cggatacaac gctatccaag ttggtttcga tgacaaacgc gaagtattga
    29461 gcaacaaacc tgctaaagga catgtagcga aagctaacac ggctcctaag cgcttcattc
    29521 gtgaattcaa aaacgttgaa ggcttggaag ttggtgctga aattacagtt gaaacattcg
    29581 cagctggaga tgttgttgat gtaactggta cttctaaagg taaaggtttc caaggtgtta
    29641 tcaagcgcca cggacaatca cgtggaccga tggctcacgg ttctcgttac caccgtcgtc
    29701 caggttctat gggacctgtt gcacctaacc gcgtattcaa aggtaaaaac cttgcaggac
    29761 gtatgggtgg tgaccgcgta acaattcaaa atcttgaagt tgtacaagtt gttccagaaa
    29821 agaacgttat ccttatcaaa ggtaacgtac caggtgctaa gaaatctctt atcactatca
    29881 aatcagcagt taaagctggt aaataataaa gaaaggggaa atcagtcaca atggcaaacg
    29941 taacattatt tgaccaaact ggtaaagaag ctggccaagt tgttcttaac gatgcagtat
    30001 ttggtatcga accaaatgaa tcagttgtgt ttgatgtaat catcagccaa cgcgcaagcc
    30061 ttcgtcaagg aacacacgct gttaaaaacc gctctgcagt atcaggtggt ggacgcaaac
    30121 cgtggcgtca aaaaggaact ggacgtgctc gtcaaggttc tatccgctca ccacaatggc
    30181 gtggtggtgg tgttgtcttc ggaccaactc cacgttcata cggctacaaa cttccacaaa
    30241 aagttcgtcg cctagctctt aaatcagttt actctgaaaa agttgctgaa aacaaattcg
    30301 tagctgtaga cgctctttca tttacagctc caaaaactgc tgaatttgca aaagttcttg
    30361 cagcattgag catcgattct aaagttcttg ttatccttga agaaggaaat gaattcgcag
    30421 ctctttcagc tcgtaacctt ccaaacgtga aagttgcaac tgctacaact gcaagtgttc
    30481 ttgacatcgc aaatagcgac aaacttcttg tcacacaagc agctatctct aaaatcgagg
    30541 aggttcttgc ataatgaatt tgtatgatgt tatcaaaaaa cctgtcatca ctgaaagctc
    30601 aatggctcaa cttgaagcag ggaaatatgt atttgaagtt gacactcgtg cacacaaact
    30661 tttgatcaag caagctgttg aagctgcttt cgaaggtgtt aaagttgcca atgttaacac
    30721 aatcaacgta aaaccaaaag ctaaacgtgt tggacgttac actggtttta ctaacaaaac
    30781 taaaaaagct atcatcacac ttacagctga ttctaaagca atcgagttgt ttgctgctga
    30841 agctgaataa tctaaggagg aaatatcgtg ggaattcgtg tttataaacc aacaacaaac
    30901 ggtcgccgta atatgacttc tttggatttc gctgaaatca caacaagcac tcctgaaaaa
    30961 tcattgcttg ttgcattgaa gagcaaggct ggtcgtaaca acaacggtcg tatcacagtt
    31021 cgtcaccaag gtggtggaca caaacgtttc taccgtttgg ttgacttcaa acgtaataaa
    31081 gacaacgttg aagcagttgt taaaacaatc gagtacgatc caaaccgttc tgcaaacatc
    31141 gctcttgtac actacactga cggtgtgaaa gcatacatca tcgctccaaa aggtcttgaa
    31201 gtaggtcaac gtatcgtttc aggtccagaa gcagatatca aagtcggaaa cgctcttcca
    31261 cttgctaaca tcccagttgg tactttgatt cacaacatcg agttgaaacc aggtcgtggt
    31321 ggtgaattgg tacgtgctgc tggtgcatct gctcaagtat tgggttctga aggtaaatac
    31381 gttcttgttc gtcttcaatc aggtgaagtt cgtatgattc ttggaacttg ccgtgctaca
    31441 gttggtgttg tcggaaacga acaacatgga cttgtaaacc ttggtaaagc aggacgtagc
    31501 cgttggaaag gtatccgccc aacagttcgt ggttctgtaa tgaaccctaa cgatcaccca
    31561 cacggtggtg gtgaaggtaa agcaccagtt ggtcgtaaag caccatctac tccatggggc
    31621 aaacctgctc ttggtcttaa aactcgtaac aagaaagcga aatctgacaa acttatcgtt
    31681 cgtcgtcgca acgagaaata atattaaact agtcgcttaa gcaactagta aatccgccag
    31741 ctcggtagcg ctccatagga gtgcaagccg ctgtggtaca acatttaaag gagaaaatat
    31801 aaaaatggga cgcagtctta aaaaaggacc tttcgtcgat gagcatttga tgaaaaaagt
    31861 tgaagctcaa gctaacgacg aaaagaaaaa agttattaaa acttggtcac gtcgttcaac
    31921 gatcttccca agtttcattg gttacactat tgcagtttat gacggacgta aacacgtacc
    31981 tgtttacatc caagaagaca tggtaggcca caaacttggt gaatttgcac caactcgtac
    32041 ttacaaaggt cacgctgcag acgacaagaa aacacgtaga aaataaggag aacataaatg
    32101 gcagaaatta cttcagctaa agcaatggct cgtacagtac gtgtttcacc tcgtaaatca
    32161 cgtcttgttc ttgataacat ccgtggtaaa agcgtagccg atgcaatcgc aatcttgaca
    32221 ttcactccaa acaaagctgc tgaaatcatc ttgaaagttt tgaactcagc tgtagctaac
    32281 gctgaaaaca actttggttt ggataaagct aacttggtag tatctgaagc attcgcaaac
    32341 gaaggaccaa ctatgaaacg tttccgtcca cgtgcgaaag gttcagcttc accaatcaac
    32401 aaacgtacag ctcacatcac tgtagctgtt gcagaaaaat aaggaggtaa aatcgtgggt
    32461 caaaaagtac atccaattgg tatgcgtgtc ggcatcatcc gtgattggga tgccaaatgg
    32521 tatgctgaaa aagaatacgc ggattacctt catgaagatc ttgcaatccg taaattcgtt
    32581 caaaaagaac ttgctgacgc agcagtttca actattgaaa tcgaacgcgc agtaaacaaa
    32641 gttaacgttt cacttcacac tgctaaacca ggtatggtta tcggtaaagg tggtgctaac
    32701 gttgatgcac tccgtgcaaa acttaacaaa ttgactggaa aacaagtaca catcaacatc
    32761 atcgaaatca aacaacctga tttggatgct caccttgtag gtgaaggaat tgctcgtcaa
    32821 ttggagcaac gtgttgcttt ccgtcgtgca caaaaacaag caatccaacg tgcaatgcgt
    32881 gctggagcta aaggaatcaa aactcaagta tcaggtcgtt tgaacggtgc agatatcgcc
    32941 cgtgctgaag gatactctga aggaactgtt ccgcttcaca cacttcgtgc agatatcgat
    33001 tacgcttggg aagaagcaga tactacatac ggtaaacttg gtgttaaagt atggatctac
    33061 cgtggtgaag ttcttccagc tcgtaaaaac actaaaggag gtaaataacc aatgttagta
    33121 cctaaacgtg ttaaacaccg tcgtgagttc cgtggaaaaa tgcgcggtga agcaaaaggt
    33181 ggaaaagaag tagcattcgg tgaatacggt cttcaagcta caactagcca ctggatcact
    33241 aaccgccaaa tcgaagctgc tcgtatcgcc atgactcgtt acatgaaacg tggtggtaaa
    33301 gtttggatta aaatcttccc acacaaatca tacactgcta aagctatcgg tgtgcgtatg
    33361 ggatctggta aaggggcacc tgaaggttgg gtagcaccag ttaaacgtgg taaagtgatg
    33421 ttcgaaatcg ctggtgtatc tgaagagatt gcacgtgaag cgcttcgact tgctagccac
    33481 aaattgccag ttaaatgtaa attcgtaaaa cgtgaagcag aataaggaga aggcatgaaa
    33541 cttaatgaag taaaagaatt tgttaaagaa cttcgtggtc tttctcaaga agaactcgcg
    33601 aagcgcgaaa acgaattgaa aaaagaattg tttgaacttc gtttccaagc tgctactggt
    33661 caattggaac aaacagctcg cttgaaagaa gttaaaaaac aaatcgctcg tatcaaaaca
    33721 gttcaatctg aagcgaaata atagactagg gaaggagaaa tttcaatgga acgcaataat
    33781 cgtaaagttc ttgttggacg tgttgtatct gacaaaatgg acaagacaat cacagttgta
    33841 gttgaaacaa aacgtaacca cccagtctat ggtaaacgta ttaactactc taaaaaatac
    33901 aaagctcatg atgaaaacaa tgttgccaaa gaaggcgata tcgtacgtat catggaaact
    33961 cgcccgcttt cagctacaaa acgtttccgt cttgtagaag ttgttgaaga agcggtcatc
    34021 atctaatcaa acctgaaagg agaaaactga aatgattcaa acagaaactc gtttgaaagt
    34081 cgcagacaac agcggtgctc gcgaaatctt gactatcaaa gttcttggtg gttcaggacg
    34141 taaatttgca aacatcggtg atgttatcgt ggcatctgta aaacaagcta ctcctggtgg
    34201 tgcggttaaa aaaggtgacg ttgttaaagc agttatcgtt cgtactaaat caggtgctcg
    34261 tcgtgctgat ggttcataca tcaaatttga cgaaaacgca gcagttatca tccgtgaaga
    34321 caaaactcct cgcggaacac gtatctttgg cccagttgca cgtgaattgc gtgaaggtgg
    34381 cttcatgaag atcgtgtcac ttgctccaga agtactttaa tttttaggaa caaactagtc
    34441 ccctagcttc aagctagggt gcccttatgg gcgtaagaaa aatcaaggag aaacctaatg
    34501 tttgtaaaaa aaggcgacaa agttcgcgta atcgctggta aagataaggg aacagaagct
    34561 gttgtcctta ctgcccttcc aaaagtaaac aaagttatcg ttgaaggtgt taacattgtt
    34621 aagaaacacc aacgtccaac taacgagctt cctcaaggtg gtatcatcga gaaagaagca
    34681 gctatccacg tatcaaacgt tcaagttttg gacaaaaatg gtgtagctgg tcgtgttgga
    34741 tacaaatttg tagacggtaa aaaagttcgc tacaacaaaa aatcaggcga agtgcttgat
    34801 taatcacgaa ggaaaggaga agtataatgg caaatcgttt aaaagaaaaa tatcttaatg
    34861 aagtagttcc tgctttgaca gaacaattca actactcatc agtgatggct gtgcctaaag
    34921 tagataagat tgttttgaac atgggtgttg gtgaagctgt atcaaacgct aaaagccttg
    34981 aaaaagctgc tgaagaattg gcacttatct caggtcaaaa accacttatc actaaagcta
    35041 aaaaatcaat cgccggcttc cgtcttcgtg aaggtgttgc gatcggtgca aaagttaccc
    35101 ttcgtggtga acgtatgtac gaattcttgg ataaattggt atcagtttca cttccacgtg
    35161 tacgtgactt tcacggtgtt ccaacaaaat catttgatgg acgcgggaac tacacacttg
    35221 gtgtgaaaga acaattaatc ttcccagaaa tcaacttcga tgacgttgac aaaactcgtg
    35281 gtcttgacat cgttatcgta acaactgcta acactgacga agagtcacgt gcattgctta
    35341 caggccttgg aatgcctttt gcaaaataat ataggaggta aatctaatgg ctaaaaaatc
    35401 aatggtagct agagaggcta aacgccaaaa aattgttgac cgttatgctg aaaaacgtgc
    35461 tgcattaaag gcggcagggg actacgaagg tttatctaaa ttacctcgca acgcctcacc
    35521 gactcgttta cataatcgtt gtagagttac ggggcgccca cattcagttt accgcaaatt
    35581 tggtctgagt cgtatcgctt ttcgcgaact tgcgcataaa ggtcaaattc ctggtgtaac
    35641 aaaagcatct tggtaattta agatatcaag ggtgtcaaaa ctccaagtaa aaataggaaa
    35701 cttgacgaag aaactaaagt ttctaggaaa gtttatcttt ttcacacaga gtttagcccg
    35761 ggttcaattg ggcttgccaa tttgaacccg agctacagct ttggcaaaaa agaccaattt
    35821 gctttggagc attgcttctg cattaaattg tctatttttg ctcgtgctgt tacgctcttt
    35881 gtatcatgta ttaactagca agtgcaactt gcaaactact agtaagagga gaaaaacaaa
    35941 atggttatga ctgacccaat cgcagacttc ctaactcgta ttcgtaatgc taaccaagct
    36001 aaacacgaag tacttgaagt acctgcatca aacatcaaaa aagggattgc tgaaatcctt
    36061 aaacgcgaag gttttgtaaa aaacgttgaa atcatcgaag atgacaaaca aggcgtcatc
    36121 cgtgtatttc ttaaatacgg accaaatggt gaaaaagtta tcactaactt gaaacgtgtt
    36181 tctaaaccag gacttcgtgt ctacaaaaaa cgtgaagacc ttccaaaagt tcttaacgga
    36241 cttggaattg ccatcctttc aacttctgaa ggtttgctta ctgataaaga agcacgccaa
    36301 aagaatgttg gtggtgaggt tatcgcttac gtttggtaaa atcaagatac aaagctcgta
    36361 aagaacaaag caaaattagg aagttggaga agtttgttta caaacaagcc aacttatcta
    36421 ttttgcacag ttcttagagc gtgttcagtt cagctcttga actaaataag tatctgaacc
    36481 ccgtgaaaac tggccgttct ggcctgacaa tttaacagga gaaaataaac atgtcacgta
    36541 ttggtaataa agttatcgtg ttgcctgctg gtgttgaact cgctaacaat gacaacgttg
    36601 taactgtaaa aggacctaaa ggagaactta ctcgtgagtt ctcaaaagat attgaaatcc
    36661 gtgtggaagg tactgaaata actcttcacc gtccaaacga ttcaaaagaa atgaaaacta
    36721 tccacggaac tactcgtgcc cttttgaaca acatggttgt tggtgtatca gaaggattca
    36781 agaaagaact tgaaatgcgt ggggttggtt accgtgcaca gcttcaagga tctaaacttg
    36841 ttttggctgt tggtaaatct catccagacg aagttgaagc tccagaagga attacttttg
    36901 aacttccaaa cccaacaaca atcgttgtta gcggaatttc aaaagaagta gttggtcaaa
    36961 cagctgctta cgtacgtagc cttcgttcac cagaaccata taaaggtaaa ggtatccgtt
    37021 acgttggtga attcgttcgc cgtaaagaag gtaaaacagg taaataatgt tgagtggttg
    37081 atcatcaacc accaacctat tttccaactt tgtgcatagc acacgattta aaactaaaga
    37141 ggtgaaaact gtgatttcaa aaccagataa aaacaaactc cgccaaaaac gccaccgtcg
    37201 cgttcgcgga aaactctctg gaactgctga tcgcccacgt ttgaacgtat tccgttctaa
    37261 tacaggcatc tacgctcaag tgattgatga cgtagcgggt gtaacgctcg caagtgcttc
    37321 aactcttgat aaagaagttt caaaaggaac taaaactgaa caagccgttg ctgtcggtaa
    37381 actcgttgca gaacgtgcaa acgctaaagg tatttcagaa gtggtgttcg accgcggtgg
    37441 atatctatat cacggacgtg tgaaagcttt ggctgatgca gctcgtgaaa acggattgaa
    37501 attctaatag gaggacacta gaaaatggca tttaaagaca atgcagttga attagaagaa
    37561 cgcgtagttg ctgtcaaccg tgttacaaaa gttgttaaag gtggacgtcg tcttcgtttc
    37621 gcagctcttg ttgttgttgg tgaccacaat ggtcgcgtag gatttggtac tggtaaagct
    37681 caagaagttc cagaagcaat ccgtaaagca gtagatgatg ctaagaaaaa cttgatcgaa
    37741 gttcctatgg ttggaacaac aatcccacac gaagttcttt cagaattcgg tggagctaaa
    37801 gtattgttga aacctgctgt agaaggttct ggagttgccg ctggtggtgc agttcgtgcc
    37861 gttgtggaat tggcaggtgt ggcagatatt acatctaaat cacttggttc taacactcca
    37921 atcaacattg ttcgtgcaac tgttgaaggt ttgaaacaat tgaaacgcgc tgaagaaatt
    37981 gctgcccttc gtggtatttc agtttctgat ttggcataag aaaggggata aaatggctca
    38041 aattaaaatt actttgacta agtctccaat cggacgcatt ccatcacaac gtaaaactgt
    38101 tgtagcactt ggacttggca aattgaacag ctctgttatt aaagaagata acgctgctat
    38161 ccgtggtatg attacagcag tatctcactt agtaacagtt gaagaagtaa actaatgaag
    38221 ttttagggga tgtgcactgt accatcccct aaaactagat atagtcatct atgatgacat
    38281 cgtataggcg agttgatggg ggagacaacc ttttctccct tatcggcgct agcattttac
    38341 aaaagaggag aaaataaaaa tgaaacttca tgaattgaaa cctgcagaag gttctcgtaa
    38401 agtacgtaac cgcgttggtc gtggtacttc atcaggtaac ggtaaaacat ctggtcgtgg
    38461 tcaaaaaggt caaaaagctc gtagcggtgg cggagttcgc cttggttttg aaggtggaca
    38521 aactccattg ttccgtcgtc ttccaaaacg tggattcact aacatcaacg ctaaagaata
    38581 cgcaattgtg aaccttgacc aattgaacgt ctttgaagat ggtgctgaag taactccagt
    38641 tgttcttatc gaagcaggaa ttgttaaagc tgaaaagtca ggtattaaaa ttcttggtaa
    38701 cggtgagttg actaagaaat tgactgtgaa agcagctaaa ttctctaaat cagctgaaga
    38761 agctatcact gctaaaggtg gttcagtaga agtcatctaa gagaggtgac ctatgttttt
    38821 taaattatta agagaagctc ttaaagtcaa gcaggttcga tcaaaaattt tatttacaat
    38881 ttttatcgtt ttggtctttc gtatcggaac tagcattaca gttcctggtg tgaatgccaa
    38941 tagcttgaat gctttaagtg gattatcctt cttaaacatg ttgagcttgg tgtcggggaa
    39001 tgccctaaaa aacttttcga tttttgccct aggagttagt ccctatatca ccgcttctat
    39061 tgttgtccaa ctcttgcaaa tggatatttt acccaagttt gtagagtggg gtaaacaagg
    39121 ggaagtaggt cgaagaaaat tgaatcaagc tactcgttat attgctctag ttctcgcttt
    39181 tgtgcaatct atcgggatta cagctggttt taataccttg gctggagctc aattgattaa
    39241 aactgcttta actccacaag tttttctgac gattggtatc atcttaacag ctggtagtat
    39301 gattgtcact tggttgggtg agcaaattac agataaggga tacggaaacg gtgtttccat
    39361 gattatcttt gccgggattg tttcctcaat tccagagatg attcagggca tctatgtgga
    39421 ctactttgtg aacgtcccaa gtagccgtat cacttcatct atcattttcg taatcatttt
    39481 gattattact gtattgttga ttatttactt tacaacttat gttcaacaag cagaatacaa
    39541 aattccaatc caatatacta aggttgcaca aggtgctcca tctagctctt accttccgtt
    39601 aaaggtaaac cctgctggag ttatccctgt tatctttgcc agttcgatta ctgcagcgcc
    39661 tgcggctatt cttcagtttt tgagtgccac aggtcatgat tgggcttggg taagggtagc
    39721 acaagagatg ttggcaacta cttctccaac tggtattgcc atgtatgctt tgttgattat
    39781 tctctttaca ttcttctata cgtttgtaca gattaatcct gaaaaagcag cagagagcct
    39841 acaaaagagt ggtgcctata tccatggagt tcgtcctggt aaaggtacag aagaatatat
    39901 gtctaaactt cttcgtcgtc ttgcaactgt tggttccctc ttccttggtg tgatttccat
    39961 tttaccgatt gcagctaaag atgtatttgg tctttctgat gttgttgcct ttggtggaac
    40021 aagtctcttg atcattatct ctacaggtat cgaaggaatc aagcaattgg aaggttacct
    40081 attgaaacgt aagtatgttg gtttcatgga cagaacagaa taaaagtatt tactgaatca
    40141 gtaaatactg agggagtgga ggtttaaact ctgacatttg taagagttgg atctcccctc
    40201 ttctattttg tttttaaatc ggggtgaaaa gactttttgc ttctatttaa aaataaaata
    40261 aggagatcaa atcatgaatc ttttgattat gggcttacct ggtgcaggta agggaactca
    40321 agcagcaaaa atcgtagaac aattccatgt tgcacatatc tcaacaggtg atatgttccg
    40381 cgctgcaatg gcaaatcaaa ctgaaatggg tgttcttgct aagtcatata ttgacaaggg
    40441 tgaattggtt cctgacgaag ttacaaatgg aatcgtaaaa gaacgccttt cacaagatga
    40501 tattaaagaa acaggattct tattggatgg ttacccacgt acaattgaac aagctcatgc
    40561 cttggacaaa acattggctg aacttggcat tgaactagaa ggtattatca atattgaagt
    40621 gaaccctgac agcctcttgg aacgtttgag tggccgtatc atccaccgcg taactggaga
    40681 aactttccac aaggtcttta acccaccagt tgactataaa gaagaagatt actaccaacg
    40741 tgaagatgat aagcctgaga cagtaaaacg tcgtttggat gttaatattg ctcaaggaga
    40801 accaatcatt gctcactacc gtgccaaagg tttggttcat gacatcgaag gtaatcaaga
    40861 tatcaatgat gtcttctcag atattgaaaa agtattgaca aatttgaaat aaagcgtttt
    40921 tcacacttgc aaaaatccgc tacaaatgtt atactgaaat agtctgactt ataattgttg
    40981 tctctgtgtc tagaggcatc gaatcgaaat ttatggaggt gcttttgcgt ggcaaaagac
    41041 gatgtgattg aagttgaagg caaagtagtt gatacaatgc cgaatgcaat gtttacggtt
    41101 gaacttgaaa atggacatca gattttagca acagtttctg gtaaaattcg taaaaactat
    41161 attcgtattt tagcgggaga tcgtgttact gtcgaaatga gtccatatga cttgacacgt
    41221 ggacgtatca cttaccgctt taaataatcg aaaaacttgg agggataaga aatgaaagta
    41281 agaccatcgg tcaaaccaat ttgcgaatac tgtaaagtta ttcgtcgtaa tggtcgtgtt
    41341 atggtaattt gcccagcaaa tccaaaacac aaacaacgtc aaggataaga tagaaaggag
    41401 aaaacatggc tcgtattgct ggagttgata ttccaaatga caaacgcgta gtaatctcat
    41461 tgacttatgt ttatggtatc ggacttgcaa catctaagaa aattttggct gctgctggaa
    41521 tctcagaaga tgttcgtgta cgtgatctta catcagatca agaagatgct atccgtcgtg
    41581 aagtggatgc aatcaaagtt gaaggtgacc ttcgtcgtga agtaaacttg aacatcaaac
    41641 gtttgatgga aatcggttca taccgtggta tccgtcaccg tcgtggactt cctgtccgtg
    41701 gacaaaatac taaaaacaac gctcgcactc gtaaaggtaa agctgttgcg attgctggta
    41761 agaaaaaata atataggagg taaaagtctt ggctaaacca acacgtaaac gtcgtgtgaa
    41821 aaagaatatc gaatctggta ttgctcatat tcacgctaca tttaataaca ctattgttat
    41881 gattactgat gtgcatggta atgcaattgc ttggtcatca gctggtgctc ttggtttcaa
    41941 aggttctcgt aaatctacac cattcgctgc tcaaatggct tctgaagctg ctgctaaatc
    42001 tgcacaagaa cacggtctta aatcagttga agttactgta aaaggtccag gttctggtcg
    42061 tgagtcagct attcgtgcgc ttgctgccgc tggtcttgaa gtaacagcaa ttcgtgatgt
    42121 gactccagtg ccacacaatg gtgctcgtcc tccaaaacgt cgccgtgtat aatcatcgca
    42181 ttacactgct tttcgtttaa gagggagtaa ctaaatgatc gagtttgaaa aaccaaatat
    42241 aacaaaaatt gatgaaaata aagattatgg caagtttgta atcgaaccac ttgaacgtgg
    42301 ctacggtaca actcttggta actctcttcg tcgtgtactt ctagcttctc taccaggagc
    42361 agctgtgaca tctatcaaca ttgatggtgt gttacatgag tttgacacag ttccaggtgt
    42421 tcgtgaagac gttatgcaaa tcattctgaa cattaaagga attgcagtga aatcgtacgt
    42481 tgaagacgaa aaaatcatcg aactggatgt tgaaggtcct gctgaagtaa cagctggtga
    42541 cattttgaca gatagcgata ttgaaattgt aaatccagat cattatctct ttacaattgg
    42601 tgaaggttct tctctaaaag cgactatgac tgttaacagt ggtcgtggat atgtacctgc
    42661 tgatgaaaat aaaaaggata atgcaccagt tggaacactt gctgtagatt ctatttatac
    42721 accagttaca aaagtcaact atcaagtgga acctgctcgt gtaggtagca atgatggttt
    42781 cgacaaatta acccttgaaa tcttgacaaa tggaacaatt attccagaag atgctttagg
    42841 gctttcagca cgtattttga cagaacatct tgatttgttt acaaatctta ctgagattgc
    42901 taagtcaact gaagtgatga aagaagctga tactgaatct gacgaccgta ttttagatcg
    42961 tacgattgag gaactggact tgtctgtgcg ttcatacaac tgtttaaaac gtgccggtat
    43021 caatactgtg catgatttga cagaaaaatc tgaagcagag atgatgaaag tacgaaatct
    43081 tggacgcaag agtttggaag aagtgaaact caaactcatt gatttgggtc ttggattaaa
    43141 agataaataa aggaggaata catggcttac cgtaaactag gacgcactag ctcacaacgt
    43201 aaagcaatgc ttcgcgattt gacaactgac cttttgatca acgaatcaat cgtgacaact
    43261 gaagctcgtg ctaaagaaat ccgtaaaact gttgaaaaaa tgattactct aggtaaacgt
    43321 ggtgatttgc atgcacgtcg tcaagcagct gctttcgtac gtaatgaaat cgcatctgaa
    43381 aactatgatg aagcaactga taagtacact tctactacag cacttcaaaa attgttctca
    43441 gaaatcgcac ctcgttatgc tgaacgtaac ggtggataca ctcgtatcct taaaactgaa
    43501 ccacgtcgtg gtgatgcagc gccaatggcg atcatcgaat tagtataaaa tcatcaattt
    43561 tgttgagtgt tatgatgatg gagtcttgtg ctcttagtct agctctggtc taccgctagg
    43621 atttcggtcc tagcgggaac actcatcata agttgggata gtagacgctt gtttacgaaa
    43681 ttgttttttt cttaagaaca acttcgtaag caggcgtttt tgagtatttt cgttagaatt
    43741 atgctatact atttgaaaag aatcctgttt aatgttaagg tttcttattt taagaagaat
    43801 tggagtttac ttatgaaagc cattataact gttgttggta aagataaatc tggaattgtt
    43861 gcaggtgttt ctggtaaaat tgcagaatta ggattgaata ttgacgatat ctctcaaact
    43921 gtattggatg aatattttac gatgatggct gttgtatcta gtgatgaaaa gcaagatttt
    43981 acctatcttc gtaatgaatt tgaagctttt gggcaaactt tgaatgtaaa aatcaatatt
    44041 cagagtgcag cgattttcga agctatgtat aatatctagg aggtcatcat ggatattaga
    44101 caagttactg aaaccatcgc catgattgag gagcaaaact tcgatattag aaccattacc
    44161 atggggattt ctcttttgga ctgtatcgat ccaaatatca atcgtgctgc ggagaaaatc
    44221 tatcaaaaaa ttacgacaaa ggcggctaat ttagtagctg ttggtgatga aattgcggct
    44281 gagttgggaa ttcctatcgt taataagcgt gtatcggtga cacctatttc tctgattggg
    44341 gcagcgacag atgcgacgga ctacgtggtt ctggcaaaag cgcttgataa ggctgcgaaa
    44401 gagattggtg tggactttat tggtggtttt tctgccttag tacaaaaagg ttatcaaaag
    44461 ggagatgaga ttctcatcaa ttccattcct cgcgctttgg ctgagacgga taaggtctgc
    44521 tcgtcagtca atatcggctc aaccaagtct ggtattaata tgacggctgt ggcagatatg
    44581 gggcgaatta tcaaggaaac agcaaatctt tcagatatgg gagtggccaa gttggttgta
    44641 ttcgctaatg ctgttgagga caatccattt atggcgggtg cctttcatgg tgttggggaa
    44701 gcagatgtta tcatcaatgt cggagtttct ggtcctggtg tggtgaaacg tgctttggaa
    44761 aaagttcgtg gacagagctt tgatgtagta gccgaaacag ttaagaaaac tgcctttaaa
    44821 atcactcgta tcggtcaatt ggttggtcaa atggccagtg agagactggg tgtggagttt
    44881 ggtattgtgg acttgagttt ggcaccaacc cctgcggttg gagactctgt agcacgtgtc
    44941 cttgaggaaa tggggctaga aacagttggc acgcatggaa cgacggctgc cttggccctc
    45001 ttgaacgacc aagttaaaaa gggtggagtg atggcctgca accaagtcgg tggtttatct
    45061 ggtgccttta tccctgtttc tgaggatgaa ggaatgattg ctgcagtgca aaatggctct
    45121 cttaatttag aaaaactaga agctatgacg gctatctgtt ctgttggatt ggatatgatt
    45181 gccatcccag aagatacgcc tgctgaaacc attgcggcta tgattgcgga tgaagcagca
    45241 atcggtgtta tcaacatgaa aacaacagct gttcgtatca ttcccaaagg aagagaaggc
    45301 gatatgattg agtttggtgg tctattagga actgcacctg ttatgaaggt taatggggct
    45361 tcgtctgtcg acttcatctc tcgcggtgga caaatcccag caccaattca tagttttaaa
    45421 aattaagaaa ataggagaaa ttttaagttc tatttaagat tagacgtgta tactataatc
    45481 attaaataaa gacctcctaa tattatttga aacagataac actgaattag tttgaatttg
    45541 attttcatct aatatcttta tttaatgaac tcctaaactt tttcataata atctccttca
    45601 aaagtcgcct gtatgggtgg cttttatttt atcattcatg atataataga agcaaacgga
    45661 ggacggaaaa tggtaaaagt acgattgtat ttggtacgtc atggcaagac catgtttaac
    45721 acgattggtc gcgcgcaagg ttggagcgat actcccttaa ctgctgaagg tgaacgaggg
    45781 attcaagagt taggaatcgg tttgcgagaa tctgatctac agtttgagcg cgcttattcg
    45841 agtgattctg gtcgtaccat tcagaccatg ggaattatcc ttgaagaact tggcttgcag
    45901 gggaaaatcc cttatcgcat ggacaagcgt atcagagaat ggtgtttcgg tagttttgat
    45961 ggagcctatg atggcgatct tttcatgggc attattcctc gtatctttaa tgtggaccac
    46021 gttcaccaat tgtcttatgc tgaactggct gagggcttgg tagaggtcga tacagctggt
    46081 tgggctgaag gctgggaaaa actcagtggc cgaatcaagg aaggctttga aatgattgca
    46141 aaagaaatgg aagatcaagg tggaggtaac gcccttgttg tcagccatgg aatgactatt
    46201 ggaaccattg tttatctgat taatggcatg catccgcatg gtctagataa tggtagcgtg
    46261 acgattcttg aatatgagga cggtcagttt agggttgaag ttgtcggtga ccgtagttac
    46321 cgagagctag gacgtgagaa gatggaagaa ggctctattt aatcagtcta gacttgcttg
    46381 ccatgagcta gggatttgat aagaatatca agataagaaa aaacagccga gggtactcct
    46441 ttcggctgtt tttgatgtgg aaaactaaag tgtaatgcta ttgcttttag agattttcat
    46501 aaacaagagc aaggaaccta ctgttagaac agtcaggata gttgacaagg ctgcggctac
    46561 accgtaattt cctctgagaa cctctgtata aatagctaca gtcattgttc ttgttttgac
    46621 attgtagagg aggatagaag tagagagttt tgaaatcatt gtgacccaag ataagatggc
    46681 tccagaaatg ataccagata gcatcattgg agttgtaatc ttagcaaagg tattgagacg
    46741 actacttcct aagctttcag cagcttcttc aatacttggt gctatttgtt gtaagctagc
    46801 aacagatgag cgaatagtat acggtaatct tctgacagat agagacataa tcaagatgaa
    46861 agcagtccct gtaatcataa gaaatccact tccaaataga ccagtattga aggaagaaat
    46921 gaaggcaatc cctagaacgg ttcctggtac aatataaggt accatactga ggctgtcaat
    46981 taagtttgta aacaaattcc gttttctaac ggctaggtag gagataaatg tcgcaaatag
    47041 aacaactaga actaaggcaa tcaaagggat acgaatggta ttgaaaatag cagatcccat
    47101 acgattgaaa gctaccttgt aactgtttgg agaataacct ttaacagata ccatacctga
    47161 tgtttttagg aaagaggtat aaattaagta gatttgaggt aaaacagaga taaagataat
    47221 tccgtagact gttgcataaa tggcagctat ttttcctttt gtagtttttt taggctcaat
    47281 tggatggagc agattcatgc tgaaactgta gcggtttgca atgtgttttt ggataaggaa
    47341 aattgccaag gcaatgataa tcgccataat tgcaaaagca gaatttcctc caacctcgct
    47401 aataaattgg gtataaatca ggacagggaa agtccgatat ccttcgccaa tcaacatagg
    47461 cgttccaaag tctgagaatg ctctcataaa tacaagcaag gatctgctag taaggttgga
    47521 actaggagag gtaaaacaac cgttacgata cgcttaaatc cgaaggaccc catgctttca
    47581 gctgcttcaa gtagagaatt gtcaatactg ttcattgttc cagcaacata tagaaatacc
    47641 agtgggaata gttgcagtgt aaagacaagt acaattcctt tgaatccata aatatcgata
    47701 gctggaagat gaagggcatt tgtcaaaaat ttagtgatga cctcatttcg tcccagcaag
    47761 agaattcagg agtaggctcc tacgaaagga gctgacatgg aagcaatgat aatcaatatt
    47821 tgtagaaatt tcttcccctt gaagtcatac atagagaaga gataagctaa tagggttcct
    47881 acaactaagg aagtgatagt agcggtaatg gaaaccttga aactgttgac tagtgtctca
    47941 gagtagtagg ctttactaaa gaaagtgaca aaattagcta gtgagaattg tccttcatgt
    48001 ataagtgctt gcttgagcac ggtaacgata ggataaacga gaaagatagg ataggtaaga
    48061 aagaggaaga aagaggaagc tgtccaaata tttagttttt tacattccat ggttgactcc
    48121 ttttatcaga ttttgggaac catctgcaga aaagctgttt aatttttgcg tattgattcg
    48181 tagacgaata cgattgcctt tttgtagatc ttcttcaaaa gttgattctt cactaacttg
    48241 aatttttgag gcaaaacctg tctcaatgaa atactccgta tttagtccaa gatagacgct
    48301 atcgctaata gttccttcaa tatctccaga ttcatctttg ataaactctt cgggacgaat
    48361 gcttacatga atagcttgct cctcaacctg atcaagagct agcattcgaa gagcatagcc
    48421 atctgaaaag acgatataag cgccgtcgct ccgtttttca agattggcag ggataatatt
    48481 tgtgcgtccg ataaaggttg ccacaaactc attagctggt ttatgataga gttcttttgg
    48541 tcggccgatt tgttggatca ccccatcttt cataacagca atttggtctg aaatagccat
    48601 ggcttcttct tggtcgtggg ttacataaac agttgtaatt cccacttcgt gttggatttc
    48661 tcggatggct tgacgtatat ccaagcgaag tttggcctcc agattactaa gtggctcgtc
    48721 catgaggaga acacttggat taaccgctaa ggcgcatgcc aaggtgacac gttgttgttg
    48781 tccaccactg agtttatcgg gctttcgatc cgcatattga gcaatttgta tgagttcaag
    48841 atacttgttg gtctgttgaa tcaattcttc ttttggaacc ttcttttgca taagaccaaa
    48901 agcaacgttg tctcggacag tcaaatgtgg gaaaatagcg tagttttgga aaaccatccc
    48961 gatattgcgt ttgctgggtt ccatattatt gatttttgta tcatcgaagt aaaattctcc
    49021 atctttgata ctgttgaaac ctgcaatcat acgaagaagg gtcgttttcc cacatcctga
    49081 agctccaaga attttggaat tgtaatgttc aaattctcaa taacagggac atcgtggtag
    49141 atttttttgg cgttaataat tttgatctca ctcatagtga acctctttta ctgtttagat
    49201 tggatatctg taaagacttc gttgtatttc ttaacgatat ctgatttatt cttgatgaca
    49261 taatcataat cttcagtgag tgttttgatt ttgtcaattg gtttcatgtt ttcgcttgtt
    49321 ttagcatttt tacgaacagg acggttagta gtggttgtac caagtgtatc ttgtacttct
    49381 tgagagataa taaaatcgat aaatttcttg gcattttcca tatttttaga ttttttaacg
    49441 atagcagcac tagcaggtag gaagacggtt ccttcttttg gatagactac cttaatgtta
    49501 gctccgtcat ttaagagttt aactgctgga tcttcataag agagaccaac agtcatttct
    49561 ccatcagcga ctgctttata gacaccagat gaacttaaac cgattttata gtatattgaa
    49621 actagaatag tacacatcta cttctaaaat attgttagaa atcgatttga ctgtcctgat
    49681 tgatttgtcc tgttcttatt tcattttact ataccatcaa taagtgtgaa aagatctttt
    49741 acataagacc aagccttatc atctttgtaa ccaccttgag cttgtagcat atttgttaat
    49801 tgagcaaagg cgctagaaga gtttgctggg tcggcagttg cgatttttcc ttttagttca
    49861 ggtttgagaa gatcgttata tccttcgatg ttcatgcctt tagttaaatc agggttgacg
    49921 attaaaacac taccatctag tgtataagga gtagagtagc cagttgtgtt ttgatattct
    49981 ttgataacat tatcattttc ttttgaagta tagttttcaa agagttctcc gtgggtagca
    50041 tattgtgtat aagaaccacc aaagataaca tcagctacag gaacttcttt ttctgactct
    50101 agttttttga aaagttctcc agtaccagct tgaatcagtt ctactttgat accatatttt
    50161 tcttcaaagg caggaatagt tgctccaatt aagtcctctg agtttggtca ataaacgact
    50221 agcgaaccac cgtctccttt atcagatgaa ctgtcatcgg cagattcatt agaagaacaa
    50281 gcagcataat acatccattt ctttttcatg atgggatatc tccgttgtgt tatttaagtt
    50341 tattttaaaa cctacaattc tattctatag tatattgaat ctataacagt acactttaac
    50401 tgctaaaata tttctataaa ttaatttgac tttcctgata gagatgttca catcttattt
    50461 caattcacta tattagagta aaattctcta caaaaagaag aatagcctat tttactattc
    50521 ttccgagtga tttcaatttc tttggggaaa tatggagata ctttttaaat actttggcaa
    50581 aatatttata gtctgaaaat ccaacttggt cagagatagc gcttaaaggg gagttgggag
    50641 attcagccat cttatctata gcttgtttca ggcgatattg taagatatat tcatttagag
    50701 tcatggggaa gtcttctttg ataaccttat atagatgctt gttatctgca aatagctaga
    50761 gcatttcaag gaaatgaact agaaataaca attaatatgg tggttcagaa ataccttttg
    50821 ataatcaata agatcttcag gatgaagtgc gttgactcca tccatttcat atttccgatt
    50881 taataaacga tatttgtttt caccaaattg atgaaaaggg agtagttgaa cttggtcgat
    50941 atttaatgag ttaaatagag tagcgaattt ttctgcatcc tctaaactat tgttaaaatt
    51001 aggaataact gggattctta aaacgatagt tttattttga gaaaaagcat aatgaatgtt
    51061 tttaataatc atttgattaa aaaccccagt cactttttta tgttttatag aattataatg
    51121 ttttaggtct gtgtagataa aatccacata ttgaattaaa tcaataaatt tttcatgatc
    51181 aacaaaggca gtagtttcaa tggcagtgtg tatgtgatgt tctttagctg attttaagat
    51241 ggctttagca aattcaaact gagcaaatat ttcacctcct gataaagtta aacctccacc
    51301 ggattcttcg taaaattctt tgtcttttaa tacctctgta ataatttctt ctacagtctt
    51361 ttcttcaccg actaaggtga atttctctcg ttgagcatct ttcatttttt caggtttcat
    51421 tctttgagat tcaggattag aacaccatgg acagcgcaga ggacatcctt ttaaaaaaac
    51481 agttgtacga atacccgggc cgtcatgaat tgaaaagtgt tgaatattaa aaataattcc
    51541 tttagatatt tccataagag ttcctcctct tcataagtct atcctatcac aaaaacgaaa
    51601 gaaaaacaat tacgaacgaa agtttaattt gttgtttttt gctttttatt ttggtagaat
    51661 aaaacggagg tgtaaaatga aaagattgga acaaattatt aaattagtat cagaatatga
    51721 aaagatcgac gttaatacat tatcggaaaa attaaatgta tcgaaagtaa cgattagaaa
    51781 agatttagat aaattagagt caaaaggttt attacacaga gagcatggat atgctgtatt
    51841 aaatagtgga gatgacttaa atgtacgttt gtcaattaac tatgaaatta agagaaaaat
    51901 tgttcaggaa gcagtaaaat tggtgtcaga taatgaaaca ataatgatag aatctggatc
    51961 gacctgtgct ttacttgctg aggaaatttg caagcaaaaa agaaatgtta cgattgtaac
    52021 aaattcattt tttatagcaa attttgtgag agcttatgat tcatgtcgta ttattgttct
    52081 tggtggagag tttcagaagg attcacaggt tactgtggga cctttattaa aagaaatgat
    52141 acagactttt catgtgcatc aagcttttgt tgggacagat ggttacgata aagagatggg
    52201 ctttacagga aaagatttaa tgcgcagtga ggtagttcaa tatatttcag cagcgtcgga
    52261 taaagtcatt gtactaactg actcaagtaa atttgataaa aggggtacag taagaagatt
    52321 tgctttaagt caagtctatg aagtaataac agacgaaaaa ctttctaaac aaaatatagc
    52381 tacattagaa aatgctggga taatggttaa ggtagtttcg taagaggtta aatgtatgaa
    52441 tcaagatagg aataaactgc tctctaaaat tgcttatctg tattatattg aaaacttaaa
    52501 tcagtcacaa atagcagcaa aattaggaat ttatagaacc tctattagta gaatgttaac
    52561 agaagcaagg aatgcaggaa ttgttaaaat tgaaatagag aattttgata ccaatatgtt
    52621 taagttggaa aattatgtaa aagaaaaata tggtctggaa agtttagaaa ttattccaaa
    52681 tgaatttgat gataatccaa caattttatc tgaaagaatt tctcaagttg cagcaggtgt
    52741 ccttaggaat ctaattgatg ataatatgaa aattggcttt tcttggggga aaagtttaag
    52801 taatttagta gatttaattc acagtaaaag tgtccgaaat gttcacttct atcctctagc
    52861 aggtggtcct agtcacatac acgctaaata ccatgtgaat acactgattt atgaaatgtc
    52921 tagaaaattt catggagagt gtacatttat gaatgcaacg attgtgcaag aaaataaatt
    52981 gttagcagat ggtattttgc aatcaagata ttttgaaaat ttgaaaaata gttggaaaga
    53041 tttagatata gctgtagtcg gaattggtga ttttagcaat aaaggaaagc atcaatggtt
    53101 agacatgctt acagaggatg actttaaaga attgaccaaa gttaaaactg taggagaaat
    53161 ttgttgtcga ttttttgatt caaaaggtaa agaagtctat gaaaacttac aggaaagaac
    53221 gatagcaatc tctttggaag atttaaaaaa tattcctcaa agtttagctg ttgcttacgg
    53281 tgatacgaaa gtatcttcga ttctttctgt cttgcgtgct aatttagtaa atcatttgat
    53341 tacagacaaa aatacaattt taaaagtttt ggaagaagat ggggatttga cttttagaga
    53401 gattctaggt gagtgaaaat gatagactga ttcagtttat cgtttttctt tttagttgat
    53461 tgcacatttg tgcttatata aacaaaaata gtttatctgt tgtttttgga ttgacaactt
    53521 tattatgtag ttgtattcta tagttacaaa agaaaatttt aaaatttcaa atgaaaaaag
    53581 ttttttacat agtgaaatga ggaggaattt atggaaatta ttgttccaga tcaaattatc
    53641 atgggtttaa ttttatatgc tggtgatgcg aaacaacata tttataaagc gttagattac
    53701 ataaaaaatg gtacatgtga acggtgtgaa gaagaaatcc agttagctga tgcagcctta
    53761 ttagaagctc ataatctaca aacaaaattc ttggcacagg aagcgtctgg tacaaagaca
    53821 gaaattacag ctctctttgt tcattcacaa gatcatctca tgactagtat gacggagatt
    53881 aatttaatca aagaaattat tagtttgaga aaagaacttc ataaaaaata atactagagt
    53941 attatcattg ttattaacat agaggaggaa aacataatgg tgaagattgg tttgttttgt
    54001 gcagcaggtt tttctactgg tatgcttgta aataatatga aaattgcagc gcaatctagt
    54061 ggagttgagg cagaaataga ggcgttttct cagtctaaat tagcggatta tgcgccaaat
    54121 atagatgttg cactattggg tccacaagtt gcttatacat tagataaatc aaaagaaatt
    54181 tgtgataagt gtgatgttcc gatagctgtt attccgatga tggactatgg tatgttagat
    54241 gggaaaaaag tattagattt ggccctatct ttgattagtg ggtaagaaaa ggagatttat
    54301 tatgtcaaag atggatgttc agaaaatcat tgcaccgatg atgaagtttg tgaatatgcg
    54361 tggcattata gctctaaaag atgggatgtt agcaattttg ccattgacag tagttggcag
    54421 tttgttcttg attatgggac aattgccgtt cgaaggatta aataagagca ttgctagtgt
    54481 ttttggagct aattggacag agccgtttat gcaagtatat tcaggaactt ttgctattat
    54541 gggtctaatt tcttgttttt caattgccta ttcttatgct aagaatagcg gagtagaggc
    54601 tttaccagct ggagttctat ctgtatctgc attctttatt ttgctaagat catcttatat
    54661 ccctaaacaa ggtgaggcga ttggggacgc tattagtaaa gtttggtttg gaggccaagg
    54721 aattatcggt gctatcatta taggtttggt agtaggaagt atttatacct tctttataaa
    54781 gagaaaaatt gttattaaga tgccagaaca agttccacaa gctattgcca aacagtttga
    54841 agcaatgatt ccagcatttg taattttctt atcttctatg attgtatata ttttagcgaa
    54901 gtcattgact aatggcggaa cattcataga aatgatttat tctgctattc aagttccgtt
    54961 gcaaggttta actggatctt tgtatggtgc tattggaatt gcattcttta tatcattttt
    55021 gtggtggttt ggtgttcatg ggcaatcggt agtaaatgga gtagtgacag ctctgctttt
    55081 atctaatctt gatgctaata aagctatgtt agcctctgct aatctatcat tagaaaatgg
    55141 tgcacatatt gttactcaac aatttttaga ttcattttta attctatcag gttcagggat
    55201 tacgtttggt cttgtagttg ccatgctttt tgcagcaaaa tcaaaacaat accaagcctt
    55261 aggaaaagtt gcagcttttc cagcaatatt taacgtaaat gagccagttg tatttggatt
    55321 tccgattgtc atgaatccag ttatgtttgt acctttcatt cttgttcctg tacttgcagc
    55381 tgtgatagta tatggagcta ttgcaacagg tttcatgcag ccattctcag gggtaacatt
    55441 gccttggagt acaccagcta ttctatcagg atttttggtg ggtggatggc aaggtgttgt
    55501 gactcagtta ttagtattgg tgatatctac agtggtttac tttccattct ttaagataca
    55561 agatcgttta gcttaccaaa atgaaatcaa acaatcttag aggtatttgt gtgttactgt
    55621 taaactcaca catttgtgct aaaaattaga gagttaaaat ttttctagtt aaaagcttga
    55681 aaatttctat aaaaatcggt attatatttt cgaaagaaat aaaaatattt tcgaaagaaa
    55741 ggtgcttacg atggtaaata cagaagtagc aagaacaaca atcaaaacag aatattttgg
    55801 cagtcttact gaaaggatga acaaatatcg agaagatgtt ttaaataaaa aaccttatat
    55861 tgatgctgag agagcagttc tagcaacacg cgcctatgaa cgatacaagg aacaacctaa
    55921 tgtcctaaaa cgtgcatata tgctgaaaga aattttggaa aatatgtcta tctatattga
    55981 agaagaatct atgattgcgg gaaatcaagc ttcttccaat aaagatgctc ctatttttcc
    56041 ggaatatacg ctagaatttg ttctcaatga gttggatctt tttgaaaagc gtgatggaga
    56101 tgttttctat attacagaag aaacaaaaga acaacttaga agtattgctc cgttttggga
    56161 aaataataat ttacgtgcta gagctggtgc cttattacct gaagaagtgt cagtttatat
    56221 ggaaacagga ttcttcggta tggaaggtaa gatgaattct ggagatgctc acttagcagt
    56281 taactatcag aaacttttgc aatttggttt aagaggtttt gaagagcggg ctcgtaaagc
    56341 aaaagtagct ctagatttaa cagatccagc aagtattgat aaatatcatt tttacgactc
    56401 tatatttatc gtaatcgatg ctattaaagt atatgcaaag cgctttgttg ctcttgctaa
    56461 aagtttagcc gaaaatgcaa atcctaaacg taagaaagaa ttacttgaga ttgcagatat
    56521 ttgctctaga gtcccatatg aaccggcaac tacttttgca gaagctattc aatcagtttg
    56581 gtttattcaa tgtattttac aaattgaatc taatggccac tctctttcat atggccgttt
    56641 tgatcaatat atgtatccat atatgaaggc tgatttagaa agtggtaaag aaacagaaga
    56701 tagcattgtt gaacgtctga caaatctttg gattaagaca attacaatta ataaggttcg
    56761 cagtcaatca catacatttt cttcagcagg aagtccttta tatcaaaatg ttacaattgg
    56821 tggacagact cgagataaga aggatgctgt taacccatta tcttatttgg tattaaaatc
    56881 agttgcacaa acccatctac cgcaacctaa tctaactgta cgttaccatg caggtttaga
    56941 tgctcgtttc atgaatgagt gtattgaagt gatgaaactt ggttttggta tgcctgcatt
    57001 taataatgat gagattatta ttccttcttt tattgcaaaa ggagtattgg aagatgatgc
    57061 ttatgattac agtgccattg gatgtgttga aacggcagtt ccagggaaat ggggctatcg
    57121 ttgcacaggt atgagttata tgaacttccc taaggtgcta cttatcacga tgaatgatgg
    57181 aattgatccg gcttcgggta aacggtttgc accaagcttt ggtcatttta aggatatgaa
    57241 gaacttttct gaattagaaa atgcttggga taaaacacta agatatttga cacgaatgag
    57301 tgttattgtt gaaaattcta ttgatttatc attggaacga gaagttcctg atattctatg
    57361 ttcagcattg actgatgatt gtattggtcg tggaaaacac cttaaagaag gtggagcagt
    57421 atatgattat atatcaggat tgcaagttgg aattgcaaat ttgtcggatt cgttagctgc
    57481 aattaaaaaa ttggtgtttg aggaagaacg tataagccca agtcaacttt ggcatgcact
    57541 ggaaacagat tatgccagag aagaaggtaa ggtcattcaa gaaatgttga ttcatgatgc
    57601 acctaagtat ggtaatgatg atgattatgc tgacaaattg gttactgctg cttatgacat
    57661 ttatgttgat gaaattgcta aatatcctaa tacacgttat ggaagaggtc caattggagg
    57721 aattcgttat tcaggaacat cttctatctc agccaacgta gggcagggac gtggaacatt
    57781 agcaactcca gatggacgca acgcgggtac accgttagca gagggttgtt caccatcaca
    57841 taatatggat caacacggcc ctacatctgt tttaaaatct gtttcaaaat taccaacaga
    57901 tgaaatcgta ggtggggttc tcttaaatca gaaagtaaat cctcaaacgt tagccaaaga
    57961 agaagataaa ttaaaactaa ttgctttgtt acgaacattc tttaatcgtt tacatgggta
    58021 ccatattcaa tacaatgttg tttccagaga gacgctgatt gacgctcaga aacatcctga
    58081 aaaacacaga gacttaattg ttcgtgttgc aggatactct gcattcttca atgttctttc
    58141 taaggcaacc caagatgaca ttataggacg tactgagcat actttgtaaa ataaagaggt
    58201 tctttttatg gaatttatgc ttgacacatt aaatttagat gagattaaaa agtggtctga
    58261 aattttgccg ctagctgggg taacttcaaa tcccactatt gcaaaaagag agggttctat
    58321 taattttttt gaacgaatca aagatgtaag agaattgatt ggctctacac cctctattca
    58381 tgttcaggtg atttctcaag attttgaagg catcttaaag gatgctcata aaattcgaag
    58441 acaagcagga gatgatatat ttatcaaagt acctgttact ccagctggat tacgtgcaat
    58501 aaaggcgcta aaaaaagagg gctaccatat cactgcaaca gctatttata cagttattca
    58561 gggattatta gctatcgaag caggagcgga ttacctagct ccatattata atagaatgga
    58621 aaatctgaac attgattcaa attctgtcat tcgtcaatta gctcttgcta ttgatagaca
    58681 gaactctcct agtaagattt tagctgcatc ctttaaaaat gtagcacaag taaataatgc
    58741 tttagctgca gatgcgcatg ctgttacagc aggagcggat gtttttgaat cagctttcgc
    58801 catgccatct atccaaaagg cggttgatga tttttctgac gattggtttg ttattcaaaa
    58861 tagtcgttcc atttagatag agaggaaata catatgagaa tttttgctag tccttctaga
    58921 tatattcagg gggaaaatgc cttgtttgaa aatgccaaat caattttgga tttgggaaat
    58981 tgccctattc tattatgcga tcagttggtt tatgatattg ttggaaaacg atttgaagat
    59041 tacctacata ggtatggttt ccatattgtt ctggcgctat ttaatggtga agcttctgac
    59101 aatgaaatca atcgagttgt tgccttggct gagaaagaaa attgtgatag tattatcggt
    59161 cttggtgggg gaaagacgat tgatagcgca aaagctattg cagatttgat tgaaaagcct
    59221 gttattattg ctccaacaat tgcatcgacc gacgcacctg tatctgcttt atctgttatt
    59281 tatacagatg aaggtgcatt tgatcattat ctattttatt ctaaaaatcc agatttagtt
    59341 ttggttgata caaaagttat ttcacaagcc cctaagcgtt tattagcgtc tggtattgca
    59401 gatggtttag caacttgggt tgaggcgcgt gcggttatgc aggcaaatgg aaaaactatg
    59461 ttgggacaac agcaaacatt ggctggagtt gcaattgcga agaaatgtga agaaacgctg
    59521 tttgcagatg gtttacaggc tatggcagct tgtgaagcta aagtggtgac accagcatta
    59581 gaaaatattg ttgaagctaa tactttattg agtggtctag gttttgaaag tggaggatta
    59641 gctgcggcgc atgcaattca taatggtttt actgcattga caggtgacat tcatcattta
    59701 acacatggtg aaaaagtagc ttatggaact ttagtacaac tattattgga aaatagacct
    59761 aaagaagaac ttgataagta tattgagttt tacaaaaaaa ttggtatgcc aacaactcta
    59821 aaagaaatgc atttggatca agttggatat gatgatttaa taaaagttgg taaacaagca
    59881 actatggagg gtgagacaat tcatcagatg ccgtttaaga tttcgccttc agatgttgct
    59941 caagctatta tcgctgtaga tgcctatgta aattcaaaat aaacaataag gactactgtt
    60001 ttccaaatgg tagtctttta ttgatccctg tattgaattc tatagaagat tgaaatagga
    60061 tgagaacaaa tcgattggga aagtaaaatt aatttctata aatgttttag caattgtttc
    60121 gtactatttc agattcagtc tactatacgt tcttcataaa tcaaaaagcg acataggtag
    60181 tcggctattt attgtgagta cattaattag cattccagtt ttatcttcgg tctaaaataa
    60241 gtattttgtg ctatacgaga taagcttctt gacttactcc ttgatttact gcataacaat
    60301 gggataaaaa gtgggagata gagcaattca tagtcatcaa aattaatgag atacagtata
    60361 cagtttttcc tttaaacaca tttcaaattc cctcaaaaat ggtataatag taacatcaca
    60421 aaattggaga gagaccatga gtttttacaa tcataaagaa attgagccta agtggcaggg
    60481 ctactgggca gaacatcata catttaagac aggaacagat gcatcaaaac ctaagtttta
    60541 tgcgcttgat atgttccctt atccgtctgg agctggtctg cacgtaggac acccagaagg
    60601 ttatactgca accgatatcc tcagtcgtta caaacgtgcg caaggctaca atgtccttca
    60661 cccaatgggt tgggatgctt ttggtttgcc tgcagagcaa tacgctatgg atactggtaa
    60721 tgacccagca gaatttacag cggaaaacat tgccaacttc aaacgtcaaa tcaatgcgct
    60781 tggattttct tatgactggg atcgtgaagt caatacaaca gatccaaact actacaagtg
    60841 gactcaatgg attttcacca agctttacga aaaaggcttg gcctatgaag ctgaagtgcc
    60901 agtaaactgg gttgaggaat tgggaactgc cattgccaat gaagaagtgc ttcctgacgg
    60961 aacttctgag cgtggaggct atccagttgt ccgcaaacca atgcgccaat ggatgctcaa
    61021 aatcacggct tacgcagagc gcttgctcaa tgacttagat gaactagatt ggtcagagtc
    61081 tatcaaggat atgcaacgca actggattgg taaatcaact ggtgccaatg taactttcaa
    61141 agtaaaagga acagacaagg aatttacagt ctttactact cgtccggaca cacttttcgg
    61201 tgcgactttc actgtcttgg ctcctgaaca tgaattagta gacgctatca caagttcaga
    61261 gcaagcagaa gctgtagcag actataaaca ccaagccagc cttaagtctg acttggctcg
    61321 tacagacctt gctaaggaaa aaactggtgt ttggacaggt gcctatgcca tcaaccctgt
    61381 caatggtaag gaaatgccaa tctggattgc agactatgtc cttgctagtt atggaacagg
    61441 tgcggttatg gctgtgcctg cccacgacca acgtgactgg gaatttgcca aacaatttga
    61501 ccttccaatc gtcgaagtac ttgaaggtgg agatgtcaaa gaagctgcct acacagagga
    61561 tggcctgcat gtcaattcag acttcctaga tgaactcaac aaagaagacg ctattgccaa
    61621 gattgtggct tggttggaag aaaaaggctg tggtcaggag aaggttacct accgtctccg
    61681 cgactggctc tttagccgtc aacgttactg gggtgagcca attccaatca ttcattggga
    61741 agatggaact tcaacagctg ttcctgaaac tgaattgccg cttgtcttgc ctgtaaccaa
    61801 ggatatccgt ccttcaggta ctggtgaaag tccactagct aacttgacag attggcttga
    61861 agtgactcgt gaagatggtg tcaaaggtcg tcgtgaaacc aacactatgc cacaatgggc
    61921 tggttcaagc tggtactacc tccgctatat tgatccacac aatactgaga aattggctga
    61981 tgaggacctc ctcaaacaat ggttgccagt agatatctac gtgggtggtg cggaacatgc
    62041 tgtacttcac ttgctttacg ctcgtttctg gcacaaattc ctctatgacc tcggtgttgt
    62101 tccgactaag gaaccattcc aaaaactctt taatcaaggg atgattttgg gaacaagcta
    62161 ccgtgaccac cgtggtgctc ttgtggcaac cgacaaggtt gaaaaacgtg atggttcctt
    62221 ctttcatgta gaaacagggg aagagttgga gcaagcgcca gccaagatgt ctaaatcgct
    62281 caagaacgtt gttaacccag acgatgtggt ggaacaatac ggtgccgata cccttcgtgt
    62341 ttatgaaatg tttatgggac cactcgatgc ttcgattgct tggtcagaag aaggtttgga
    62401 aggaagccgt aagttccttg accgagttta ccgtttgatt acaagtaaag aaatccttgc
    62461 ggaaaacaat ggtgctcttg acaaggttta caacgaaact gttaaagctg tcacagagca
    62521 aattgattcc ctcaaattca acacagccat tgcccaactt atggtctttg tcaatgcggc
    62581 taacaaggaa gacaagctct atgttgacta tgccaaagga tttatccaat tgattgcccc
    62641 atttgcacct cacttggcag aagaactctg gcaaactgtt gctgcaacag gtgagtcaat
    62701 ctcttacgtg acttggccaa catgggacga aagtaaactg gttgaagacg aaatcgaaat
    62761 cgttgtccaa atcaaaggta aagtccgtgc caaactcatg gtcgctaaag acctatcacg
    62821 tgaagaattg caagaaattg ctctagcgga tgaaaaagtc aaagcagaaa ttgacggtaa
    62881 ggaaatcgtg aaagtgatta gtgtaccaaa taaattggtt aatatcgtcg ttaaataacg
    62941 agtttattag ctctatctgc caccttcaat agtccactgg actattgaag ccaactaaat
    63001 tagttaacat tgttgtgaaa taaaaagaag taactctaga gtatgaactt tagagttact
    63061 tttagaatag gtcagaatga atagattagt gaacgatagc aggaagtgtg aaattttatt
    63121 atttaagatt tctattattg tagtgtcagt tatagtatta gtaatgtaaa tagtgggtgc
    63181 atattatttt aaaaattgtc tttgggacaa ggaaagttta aatttgacac tcactttaga
    63241 cactctcttt gcagttttta ttactttctt tagtttttca aatgataaat caagcaatat
    63301 ttttggaata tctccaaatg aaattataag gacacagtct gaagtgtatc aatttttatt
    63361 tacaaaatct tttgcaactc tattaatagt gacaaatttg ttatccatta ttcattattt
    63421 tggagccaaa aatttaatag tttcttttaa tgaaacttat cctcgtattc aatccagtgt
    63481 tggtatcatg tggctaccac tgtttggtat tctgataatc tattttattt ggctcttaat
    63541 agagggatta aaatatatca gaaaaataaa ttatattatt caaaataggg aaataatcta
    63601 tttttattcg caggtaaaag ttgtagataa acttactgat tctgaatcga aaaaatacgg
    63661 tgaatatatt gatttgtacg aatcgtgtcg tcagaacaat ttaagtgttc tacttaactt
    63721 tcttcaaaat tcggatgata aacgaggagt tattgctagt aactcagtga gaattatgtt
    63781 tgaatctttg gataaagcag accaaattgc ggccctgaat atttgtagaa actatgtagc
    63841 acgagaaaat gttttaaata aagaagatgc agaaaaattg ttaaatgaaa ttgataaaaa
    63901 acttgaaatt agcagatagg acaattcaaa tagagttgag taaaaagttt gaaaagtgaa
    63961 acaaggagaa agctatgcca gtaaatgaat atggtcagat gattggtgag tcaatggaag
    64021 gttatacacc cggtgcactg ccttctattg atttcttaga agggcgttat gctaggatag
    64081 aggctctctc ggtagaaaaa catgcggagg atttgctagc tgtttatggc ccggatactc
    64141 ctcgggagat gtggacctat ctttttcagg agccagtagc agatatgggg gagctggtta
    64201 gccttttaaa tcagatgttg gctcgtaagg accgttttta ctatgcaatc atagacaagg
    64261 cgactggtaa ggctttggga actttttctc tcatgcgcat tgaccagaat aaccgagtaa
    64321 tagaagtcgg agcagtcact ttttctccag agctaagggg tacacggata ggaactgagg
    64381 ctcagtatct cctagctcgc tatatttttg aggagctaaa ctatcgtcgc tacgagtgga
    64441 aatgcgatgc cttaaatctg ccatccagac gagttgcgga gcgtttggga tttgtctatg
    64501 aaggaacctt ccgccaggcg gtggtttata aggggcgtac gagagatacg gattggttgt
    64561 ctatgattga tatggactgg cctcaagtca aagatcgttt ggaaacatgg ctgcgtcctg
    64621 aaaattttga taaaaatgga cagcagtaca agagcttgag agaactttaa gaggtgttga
    64681 gatgattact attaaaaagc aagaaattgt caagctagag gatgttttgc atctctatca
    64741 ggctgtcggt tggacaaatt atacccatca accagagatg ctggagcatg ccttatcgca
    64801 ttcattagta atttatctgg cacttgatgg tgatgctgtg gtgggcttga ttcgtttggt
    64861 tggagatgga ttctcatcag tttttgtaca ggatttgatt gttttaccaa tctatcagcg
    64921 tcaagggatt ggtagtgccc taatgaaaga ggccttaaaa gattacaaag atgcttatca
    64981 agtccagctg gtgacagaag agacagaaaa aaacgtggga ttttatcgtt ctatgggctt
    65041 tgaaatctta tccacctata attgtatagg gatgacttgg gcgaatcgag aaaaataaca
    65101 aaacttgttt tttcttaagc aaaatttaag gatggtctag tattatatag tcattaaata
    65161 aagacctcct aactttattt aataaaatcc taaacttttt tcatcacaat ctcctaatga
    65221 agccacccaa tcaggtggct tttttgcgtg gtgaggtgct ggtgatagaa attttttgca
    65281 aaatagtaaa attttagaaa agttaagcta gttttaagtt tcgtcttgta tcatgtagtt
    65341 attaaataaa gacctcctaa ctttatttaa taaaatccta aacttttctt tttcataata
    65401 atctccctta actccaccca atcaggtgga gttttttagc tctatttcag gcttttgggg
    65461 actattctaa aaataatttt tcgatatttt tcggtatttt tcggattttg gtcggggaat
    65521 tggcggggac ttttttagcg aatataacta agaaataggt ctgtggtcgc ttcagctagt
    65581 tcaaactcaa tttgattgta agtgactgtt aattgaagaa ctggaactac tgtaataatg
    65641 attttgcttg tctagtagtg gcgtattaaa tgagaagtga catgtaagat tgtctcttcg
    65701 tttacgaaat caaaatttct atgaaattga tagaatccct aacgttctct taatcttaac
    65761 cgtcttgtcg tacagcggtt gaagaaaatg taaacctttg acaaaattcg tgaactatgg
    65821 gataataaaa aggaattgag tactagttct atatcatagg ctagaaaaga ccccaagctc
    65881 acgaccaaat aagcttgggg tcttttttga cactatttgt ccttgtttag ccatttatcg
    65941 actatacgaa gaacgacacc gaccacaatt ggtccgatga tagttttgag tactaattcc
    66001 atcatgggct atctcacctc ctttcgtagg cggtgtagca gtgtcgtaga atattatacc
    66061 acataagtgc taaacttagg agtcacccaa tcaggtggct tttttgtttg tggcttggtt
    66121 ttttgatata atagagccat gagtagaatt ttagataatg agataatggg ggatgaggag
    66181 ttagtagaac gcacgctccg tcctcagtat ttacgtgaat atattgggca ggataaggtt
    66241 aaggaccagc ttcaaatctt tatagaagct gccaaaatgc gagatgaagc gctggatcat
    66301 gtcctcttat ttgggcctcc aggtttgggg aaaacaacca tggcttttgt cattgccaat
    66361 gaactgggag tcaatctcaa gcaaacgtct ggtcctgtta tcgaaaaagc gggtgatttg
    66421 gtagcgattt tgaatgagtt agagcctgga gatgtcctct ttattgacga gattcatcgc
    66481 ttacccatgt cagtggaaga agtgctttat agtgccatgg aggacttcta catcgatatt
    66541 atgattgggg ctggtgaagg cagtcgcagt gttcatttgg agttgcctcc ttttaccttg
    66601 attggtgcga cgactcgggc tggtatgctc tcaaatccac tacgggcacg ttttgggatt
    66661 acaggtcata tggagtatta tgcccatgct gacttgacag aaattgtcga gcggacggca
    66721 gatatttttg agatggaaat cactcatgag gcagcatctg agttggccct acgtagtcgt
    66781 ggaacccctc gtattgccaa tcgtctcctc aagcgcgtgc gcgattttgc ccagataatg
    66841 gggaatgggg taatcgatga tattattacc gataaggctt tgactatgct ggatgttgac
    66901 catgaaggtt tggactatgt ggatcaaaaa atccttcgta ccatgattga gatgtacagt
    66961 ggaggacctg ttggtctagg aactctttct gtcaatatcg ccgaagagcg tgagacagtt
    67021 gaagacatgt atgagcctta cttgattcaa aaaggtttta tcatgcggac acggtctgga
    67081 cgggtggcga ctgctaaggc atatgagcac ttaggttatg aatacagtga aaaataagca
    67141 agaaatctta gaggctttta gagaaaatcc agatatgatg gccattctga cgatcatccg
    67201 agaccttggt ttgaaagact cgtagttggc agcaggttct gtcagaaatt tcatctggaa
    67261 tcttttgtca gacaaatccc cttttgatca tgaaacagat atagatgtga ttttctttga
    67321 tccagatttt tcttatgagg aaaccttatt actggagaaa aagctgagag aggattttcc
    67381 tcagtaccag tgggaattga aaaatcaggt ctatatgcat cagcacagtc ctcacactgc
    67441 ttcctatacc agttctcgtg atgctatgag taagtatcca gaacggtgta cggcagttgg
    67501 actgcgcttg aatgaagaat cagattttga actctatgca ccttatggtt tggaggatat
    67561 tttgaatttt caagttcgtc caactcctca tttcttagaa aatgaagacc gaatggaact
    67621 ctatcaaaca cgtttatcca agaaaaattg gcaggagaaa tggaaaaatt tgatttttaa
    67681 aaatacttaa ggaaacttta agctagggag tgtacactaa gttcataagt taagaagacc
    67741 ttaacttaaa ctcctaaaac tttttcataa taatctccct ataaaaataa agtcgcccaa
    67801 tcaggcggct tatttttttg aaaaatgggc atggtgcctg agaataaata gcttagtgat
    67861 agaagaaaat ggggaaatat ggtataatga aacgatagat ttttgaatag gaataagatc
    67921 atgtttggat tttttaagaa agataaggct gtggaagtag aggttccgac acaggttcct
    67981 gctcatatcg gcatcatcat ggatggcaat ggccgttggg ctaaaaaacg tatgcaaccg
    68041 cgagtttttg gacataaggc gggcatggaa gcattgcaaa ccgtgaccaa ggcagccaac
    68101 aaactgggcg tcaaggttat tacggtctat gctttttcta cggaaaactg gacccgtcca
    68161 gatcaggaag tcaagtttat catgaacttg ccagtagagt tttatgataa ttatgtcccg
    68221 gaactacatg cgaataatgt taagattcaa atgattgggg agacagaccg cctgcctaag
    68281 caaacctttg aagctttaac caaggctgag gaattgacta agaacaacac aggattgatt
    68341 cttaattttg ctcttaacta tggtggacgt gctgagatta cacaggcgct taagttgatt
    68401 tcccaggatg ttttagatgc caaaatcaac ccaggtgaca tcacagagga attgattggt
    68461 aactatctct ttactcagca tttgcctaag gacttacgag acccagactt gattatccgt
    68521 actagtggag aattacgttt gagcaatttc cttccatggc agggagccta tagtgagctt
    68581 tattttacgg acaccttatg gcctgatttt gacgaagcgg ccttgcagga agctattctt
    68641 gcctataatc gtcgtcatcg ccgatttgga ggagtttagg aggaaatatg acccaggatt
    68701 tacagaaaag aaccttgttt gcagggattg ccctggctat tttcctacca attttaatga
    68761 ttgggggcct cttgcttcag atagcaatcg gaatcatagc catgctagcc atgcatgaac
    68821 ttttgaagat gagaggtcta gagaccatga cgatggaggg cctcttgacc ctctttgcaa
    68881 cctttgcatt gaccattccc ttggagaatt acctgacttt tttgccagtt gatgggaatg
    68941 tggttgccta tagtgttttg atttcaatca tgttaggaac gaccgttttt agcaagtctt
    69001 atacgattga ggatgcggtt ttccctcttg ctatgagctt ctacgtgggc tttggattta
    69061 atgctttact agatgctcgt gttgcaggtt tggacaaggc tctcttagcc ttgtgtatcg
    69121 tctgggcgac agacagtggt gcctatcttg ttgggatgaa ctatgggaaa cgaaagttag
    69181 caccaagggt atcgcctaat aaaacccttg agggtgcctt gggtggtatt ttaggagcaa
    69241 ttttagtaac cattatcttt atgatagttg acagtacagt tgctcttcca tatggaattt
    69301 acaagatgtc agtctttgct attttcttta gcattgctgg acaatttggt gatttactag
    69361 aaagttcgat caaacgtcat tttggtgtta aggattctgg gaaatttatc cctggacatg
    69421 gtggtgtttt ggatcgtttc gatagtatgt tgcttgtatt tccaatcatg cacttatttg
    69481 gactctttta atcaaaagac ggaggaaacg ctatgctcgg aattttaacc tttattctgg
    69541 tttttgggat tattgtagtg gtgcacgagt tcgggcactt ctactttgcc aagaaatcag
    69601 ggattttagt acgtgaattt gccatcggta tgggacctaa aatctttgct cacattggca
    69661 aggatggaac ggcctatacc attcgaatct tgcctctggg tggctatgtc cgcatggccg
    69721 gttggggtga tgatacaact gaaatcaaga caggaacgcc tgttagtttg acacttgctg
    69781 atgatggtaa ggttaaacgc atcaatctct caggtaaaaa attggatcaa acagccctcc
    69841 ctatgcaggt gacccagttt gattttgaag acaagctctt tatcaaagga ttggttctgg
    69901 aagaagaaaa aacatttgca gtggatcacg atgcaacggt tgtggaagca gatggtactg
    69961 aggttcggat tgcaccttta gatgttcaat atcaaaatgc gactatctgg ggcaaactga
    70021 ttaccaattt tgcaggtcct atgaacaatt ttatcttagg tgtcgttgtt ttttgggttt
    70081 taatctttat gcagggtggt gtcagagatg ttgataccaa tcagttccat atcatgcccc
    70141 aaggtgcctt ggccaaggta ggagtaccag aaacggcaca aattaccaag attggctcac
    70201 atgaggttag caactgggaa agcttgatcc aagctgtgga aacagaaacc aaagataaga
    70261 cggcaccgac tttggatgtg actatttctg aaaaggggag tgacaaacaa gtcactgtta
    70321 cacccgaaga tagtcaaggt cgttaccttc taggtgttca accgggggtt aagtcagatt
    70381 ttctatccat gtttgtaggt ggttttacaa ctgctgctga ctcagctctc cgaattctct
    70441 cagctctgaa aaatctgatt ttccaaccgg atttgaacaa gttgggtgga cctgttgcta
    70501 tctttaaggc aagtagtgat gctgctaaaa atggaattga aaatatcttg tacttcttgg
    70561 caatgatttc catcaatatt gggattttta atcttattcc gattccagcc ttggatggtg
    70621 gtaagattgt gctcaatatc ctagaagcca tccgccgcaa accattgaaa caagaaattg
    70681 aaacctatgt caccttggcc ggagtggtca tcatggttgt cttgatgatt gctgtgactt
    70741 ggaatgacat tatgcgactc ttttttagat aatcgaggaa tattatgaaa caaagtaaaa
    70801 tgcctatccc aacgcttcgc gaaatgccaa gcgatgctca agttatcagc catgctctta
    70861 tgttgcgtgc tggttatgtt cgccaagttt cagcaggtgt ttattcttat ctaccacttg
    70921 ccaaccgtgt gattgaaaaa gctaaaaaca tcatgcgcca agaattcgaa aagattggtg
    70981 ctgttgagat gttggctcca gcccttctta gtgcagaatt gtggcgtgaa tcaggtcgtt
    71041 acgaaaccta tggtgaagac ctttacaaac tgaaaaaccg tgaaaaatca gactttatct
    71101 taggtccaac tcacgaagaa acctttacag ctattgtccg tgattctgtt aaatcttaca
    71161 agcaattgcc actcaacctt tatcaaattc agcccaagta tcgtgatgaa aaacgcccac
    71221 gtaatggact tcttcgtaca cgtgagttta tcatgaagga tgcttatagt ttccacgcta
    71281 actatgatag tttggatagt gtttatgatg agtacaaagc agcctatgag cgtattttca
    71341 ctcgtagtgg tttagacttc aaggctatta ttggtgacgg tggagccatg ggtggtaagg
    71401 atagccaaga atttatggcc attacatctg ctcgtacaga ccttgaccgc tgggttgtct
    71461 tggacaagtc agttgcctca tttgacgaaa ttcctgcaga agtgcaagaa gaaatcaagg
    71521 cagaattgct caaatggata gtctctggtg aagataccat tgcttactca agtgagtcta
    71581 gctatgcagc taacttagaa atggcaacaa acgagtacaa accaagcaac cgtgttgtcg
    71641 ctgaagaaga agttactcgt gttgcaacgc cagatgttaa atcaattgat gaagttgcag
    71701 ctttcctcaa tgttccagaa gaacaaacga ttaaaaccct cttctacatt gcagatggtg
    71761 agcttgttgc agcccttcta gttggaaatg accaactcaa cgaagtcaag ttgaaaaatc
    71821 acttgggagc agatttcttt gacgttgcta gcgaagaaga agtggcgaat gttgttcaag
    71881 caggatttgg ttcacttgga ccagttggtt tgccagagaa tattaaaatt attgcagatc
    71941 gtaaggtgca agatgttcgc aatgcagttg tcggtgctaa cgaagatggc taccacttga
    72001 ctggtgtgaa cccaggccgt gattttactg cagaatatgt ggatatccgt gaagttcgtg
    72061 agggtgaaat ttccccagat ggacaaggtg tccttaactt tgcgcgtggt attgagatcg
    72121 gtcatatttt caaactcgga actcgctact cagcaagcat gggagcagat gtcttggatg
    72181 aaaatggtcg tgctgtgcca atcatcatgg gatgttacgg tatcggtgtc agccgtcttc
    72241 tttcagcagt gatggagcaa cacgctcgcc tctttgttaa caaaacgcca aaaggtgaat
    72301 accgttacgc ttggggaatc aatttcccta aagaattggc accatttgat gtgcatttga
    72361 ttactgtcaa tgtcaaggat gaagaagcgc aagccttgac agaaaaactt gaagcaagct
    72421 tgatgggagc tggttatgaa gtcttgacag atgaccgtaa cgaacgtgtc ggtgttaaat
    72481 ttagcgatag tgacttgatt ggtcttccaa tccgtatcac tgttggtaaa aaagcggccg
    72541 atggcattgt agaagttaag atcaaggcaa ctggtgacac cattgaggtt catgcagata
    72601 acgtgcttga aacgcttgaa atcctaagca agaaataaaa actataatca gaagaaaaac
    72661 aaggaaaaaa tgtaactagt ttttaccttg ttttttctgt ataatgggag aaatgagtag
    72721 ataaagaggt aaatgttatg ctaagatttc caaaggattt tgtctgggga tcctctactt
    72781 ctggaccgca gacagaagga cgtgtagctg gtgacggtaa gggagacaat ctctgggatt
    72841 actggttcca agtggagcca aatcgttact ataatgggat tggttcagat aagacatcga
    72901 ctttttatga aaattgggag cgggatattg agcttttgtt agagactggt cacacagtct
    72961 ttcggacttc tattcagtgg tcacggattt ttccacaagg ctgtggaaaa gtcaaccctc
    73021 aaggtgtgga tttttatcgt aaggtctttg aggctattaa ggctaaagga attcgtctgt
    73081 tagtcaatct ctatcatttt gatttacctt ttgcccttca agaggatggt gatggttggg
    73141 aaaataaggc gacagtctca gcctatgaag actatgctcg tttttgtttt gagacttatg
    73201 gagatttagt ggatcaatgg attaccttta acgagcccat cgttcctgta gaatttggtt
    73261 atttttatga tgcccattat ccacataagg tggatgcaga ggcagctgtt aaggtagcct
    73321 atcatacaca attggccagc agccgggctg ttaaggcttg ccatgaactt ttgcctgatt
    73381 ccaagattgg gattgtcctc aacttgacac cggcttatcc acgtagccag catcctgctg
    73441 atgtcaaggc agctcgtatt gcggcccttt ttcaggccca atctttctta gatccatctg
    73501 tcttggggac ttatccacag gagttggtag aaatcttgca tgaacacggt cttttacctg
    73561 atgctacaga ggaagagttg gaactcattc gtgataatac ggtggacttc cttggtgtga
    73621 actactatca acctttgcgt gttatggctc ctcgatttgc taagcatcca gatagtccac
    73681 tcttaccaga acatttttac gagccttatg tgatgcctgg acgtaaaatc aattctcacc
    73741 gtggttggga gatttatgag caagggattt atgacatcgc ccaaaatatc aaggaaaatt
    73801 atggcaatat tgagtggatg ttgactgaga atggtatggg tgttgaaggg gaagaaaaat
    73861 tccgtcaaga tggaatgatt caagatgatt accgtattga ctttgtaaaa ggtcatcttc
    73921 gtgaacttca ccgtgccatt gaagatggtg ccaactgtaa gggctacttg atttggacct
    73981 ttattgactg ctggtcatgg ctcaacagct ataaaaatcg ctatggtttg gtcgaattag
    74041 acttggaaac gcaagaacgt cgtctgaaga aatcaggcca ctggttcaaa gaattaagcg
    74101 ataataatgg attttaaaaa ggactctgac tgattatccc aatcggtcag agttttttgc
    74161 ttacaggagc ttaatttgaa ctataccaat ttttactctt gacaagtgaa agaaacaagt
    74221 atatactgtt tttgctgatt ctataaaaga tgaattagac tataccaatt ttaaggagaa
    74281 agcacagctt gcctgtgtcg tatatactat gtgtggaatt gttggtgttg ttggaaacac
    74341 aaatgcaact gatattttga ttcaagggct tgaaaagctt gaataccgtg gctatgattc
    74401 tgcgggaatt tttgtcctag atggtgctga taaccatttg gtgaaggcgg ttggtcgtat
    74461 tgcagaattg tctgccaaga cagctggtgt tgagggaaca actggtatcg gacatactcg
    74521 ttgggctact cacggaaaac caactgagga caatgctcac ccacaccgct ctgagacaga
    74581 acgttttgtc ttggtgcata atggggtgat tgagaactat cttgaaatca aggaagaata
    74641 ccttgcaggt caccacttca aggggcagac agatactgaa atagccgttc atttgattgg
    74701 aaaatttgcg gaagaagaag ggctctcagt tcttgaagcc ttcaaaaaag cccttcacat
    74761 catccgtggt tcttatgcct ttgccttggt tgactcacaa gatcctgaag tcatctacgt
    74821 agctaaaaat aaatcaccac ttttgattgg tcttggagaa ggctataaca tggtctgctc
    74881 agacgccatg gctatgattc gtgaaactaa ccaatacatg gaaatccatg accaagagtt
    74941 ggtaatcgtc aaggctgata gtgtggaagt tcaagactat gatggaaatc gtcgtgagcg
    75001 tgctagctac actgctgagc ttgacttgtc agatatcggt aagggaactt acccttacta
    75061 catgctcaag gaaattgacg agcaaccaac tgttatgcgg aaactcatcc aagcctacac
    75121 agatgaggct ggtcaagttg tcgtggaccc agatatcatt aaggctgttc aagacgcaga
    75181 ccgcatctac atccttgcag ctggaacatc ttaccatgca ggatttgctt ctaagaaaat
    75241 gttggaagaa ttgacagata caccagttga acttggaatc tcatctgagt ggggctacag
    75301 tatgccactt ctcagcaaga aaccactctt catctttatc agccaatctg gtgaaacagc
    75361 ggatagtcgt caagttttgg tcaaggctaa tgaaatggga attccaagct taacagtgac
    75421 aaacgttcca ggttcaaccc tctcacgtga agccaactat accatgctcc ttcacgcagg
    75481 tcctgaaatt gccgtggcat caactaaagc ctatacagcg caaatcgcag cccttgcctt
    75541 ccttgcaaaa gcagtcggag aagcaaatgg taatgctaaa gcgcaagcct ttgacctggt
    75601 tcatgaattg tcaatcgtag ctcagtctat cgaatcaact ctttcagaga aagaaaccat
    75661 tgaagccaag gttcgtgaac ttcttgaaac aactcgtaac gccttttaca tcggacgtgg
    75721 tcaagattac tacgtagcca tggaagcaag tctcaaactc aaagagattt cttatatcca
    75781 gtgtgaaggt tttgcggcag gagaactcaa gcacggaacc attgccttga ttgaagaagg
    75841 aacgcctgtt ttggctctct tgtcagatcc agttcttgcc aaccatactc gtggaaatat
    75901 ccaagaggtc gcagcccgtg gtgccaaagt cctcactatc gcagaagaga atgtagccaa
    75961 agataccgac gatatcgtcc ttacgaccgt acatccatac ctctcaccaa tttcaatggt
    76021 cgtaccaacg caattagtcg cttactttgc aaccctccac cgtggcctcg atgtggataa
    76081 accacgtaac cttgctaaat cagtaacggt agaataagct aaaaaagtct agttatctag
    76141 gctttttcta atgagcaaat tggttgcttg tacttaagat tcgtgttaga ataatttttc
    76201 aaattgaagg acagagatag acaaggagaa tcacaatggt agaattggga atttcaacat
    76261 ttggggaaat aacggagctt gaagggactg gacaaactta cagtcatgct gaacgcattc
    76321 gccagttggt ggcagagatt gagctggctg acaaggttgg tttggatgta tatgggattg
    76381 gtgagcacca tcgggcggat tttgcagtat cagccccaga gattgttctg gccgctgggg
    76441 cagtcaatac caagaaaatc cgtttgacca gtgcagtcag cattctgtca agcatggacc
    76501 cgattcgttt gttccaacag tatgccacta tcgatgcttt gtcaaatgga cgagcggaga
    76561 ttatggctgg aaggggctct ttcacggaat ctttccctct gtttggttat gacttgaaag
    76621 actacgactc tctttttgat gagaaattag acttgcttca gttagtcaat gaaaagacca
    76681 agttagactg gcaaggtcga ttgactcaaa cgattgctgg taaagaagtt tatcctcgtc
    76741 cagttcagga caaattgccc ttgtggatag ctacaggtgg tcatgtcgaa tcaacagtga
    76801 agattgctca ggctggtcta ccgattgtat atgctattat tggtggtaat ccacgttatt
    76861 ttaaaaagtt gattcaggct tatcgtgaga ttggaagcga agcgggtcat gctgacaaag
    76921 acttgaaagt gggagcccat tcttgggggt ggattgcgga agatggtgag caggcggtga
    76981 aagattattt ccatccgact aagcaagtgg tggatgctat ttccaaagac cgtccgcact
    77041 ggcaggaatt gcgttatgag caatatttgg agcaggtagg gccaaatggc gccatgtttg
    77101 ttggcaatcc agatcaggtg gccgaaaaat tgattcgcat gatagaggat ttaggattgg
    77161 accgcttcat gcttcatcta ccgcttggtt ctatgcctca tgaccaggtt ctgagagcta
    77221 ttgaactctt cggaacacaa gttgcaccca aagtacgagc ttattttgct atgaaagagg
    77281 cttaataaaa aatcctaatc aagtttatta ggacaacaaa tattgtacga aaattaatcc
    77341 cccgagctat aatgcttggg ggatttttct ataggagggc tagtttagtt ctctttttta
    77401 ttttttagta agaaaccgag accaaggagc gcaaggaggc tgattcctgc aaataggagt
    77461 ttgttttcgt ttttgattcc tgtatttgga agttcagctt gtttatctgg ggttgcaggt
    77521 atattttcct tgctagagtt ttctaccgat tcgtttcgaa ccgcttcttt tacagatgat
    77581 gcttgtgctt cttgtgctgg ttgttcagct tgtgaatcag ctgtagcttg gctaggttta
    77641 ttttccgcat cagctacttt ggcatctggt ttagtagaat caggtctagc ttctggagct
    77701 gggtcttgat gtgcagggtg agaagcttca ttttgatgtt caggcttgga aggggttgag
    77761 tctggtttct cttctgcagt tgactcatgg ctagttccat tttgagagac tcgaagaaca
    77821 gtagctgtaa gggcattcaa tttcaagcct ttttcagtcc attcaagtcc tttcgggttg
    77881 gcaattccga ctggtcctgc ttggttttca tctgccaaaa cttccgcatt tcttagatgt
    77941 gcaaaggcag ttcccaaatt aaattcgcga gctttttcat ccgcattgac aaagactgcg
    78001 tagatatcgc cgtttggagc agtgatttgg tagccaatca ctacatcctc tttttccaca
    78061 ccattttggc ctgggacagt gatgaggtgg acacggtctt tgatatcttg gagactctta
    78121 agtcggaagg catctgtaga ttgacgaagg gcaatcaaac ctttcatata gtcacggctc
    78181 ttgacatttt caggataagc tttaccatct gtagccttag tccagtcaaa cttgttgact
    78241 gcgtcgctag aatcgtaaga atcatggatg aagtaaggat agtcaaatgg gttgccgtcc
    78301 ttatcacgta acaagtgaga tttgtttgga accttatcct ctgctactgg agtcttgtag
    78361 gctgggtcac ggaattgttt agtacgtcca tattcctgac cggagtggat aaatggagtt
    78421 ccttgagctg tcaagaccat gagatttcca agtcgtaaac gacggtggat ttcagcatag
    78481 ttctcagcct tgcttgggtc ttttttgata gactgggcaa tgatgtcaaa gagggtcaag
    78541 ttatcatggg ctgctatgta ttggatgaca tctccagggc tgtcagcttc aaagttagtt
    78601 ggttgagcaa tgagattttt aaagatggtg ttgacatcac gcttgccacc tgtgataaag
    78661 gcaggttgac cttcgtttgg ataaccagat ttgaggttgt tacggatgtc atctgaaaag
    78721 acagcgacag tatcggtatg tttcatccaa tcttggtcag cagctttagt aggcatgttt
    78781 tcatcaccgg cataggttct ccaaccttca ccaagcatga tgaggtttgg attgagggcg
    78841 cgtgcagcct tgtaagcttc ttcgatagaa gcggcgtcat ggtctcccat catatcgaaa
    78901 cggaatccat ccactttgta ggtatcaact aggtatttga tagagtcaac taggagccgt
    78961 ttggtcatat ggtgggttgt tcccaagcgt ccaccaccaa agctagttcg aggtgtgcca
    79021 tcggcatcca taaagtggta gtagtttggc tctaggtctt caaagatatc gactttggct
    79081 gtgtggttat aaacgacatc taggatagct cccataccac gtttgtggat ttcgttgatg
    79141 aggtttttaa attctgcgat tcgtttttct ggattcttag gatcgcttga gtacatacca
    79201 gtcaaggaga agtagttttg agggtcatat ccccagttgt agttgctgtt gcttgaagtg
    79261 tagtcagaca agcgttcatg gtttttcaat tcattgacaa agtagtaaga caagactgga
    79321 aggagctgga tatgggttac acccaagtct ttgagatagt ctagtttttc aatgaaggct
    79381 tcaaaagtcc caaatggttt ggtcaagtct tttgcaatgg caggatctga agtgaagtca
    79441 cgcacatgag cttcgtagat aacggcgtct tcacgagtct tgaaattgtg aatcttacca
    79501 taagtcaagt cttgaggtcc gagtttagct ggatctacaa aggcggcttt agccacttta
    79561 tgggcatcgt caattttggc atcgtcgcta ttccaagcag caagagattt agcgtaagga
    79621 tcgagtgcaa gaacagtttt accttgacgc tcgatttggt attgataata gtagccagtg
    79681 aaatctgtga ttccgagttt gtttgtgctg tctagagttt gtttccaagt tcctctttcc
    79741 cctttttcga gagcgacagt tccaactact ttgtcagggt cattcttgtc gtagacaaca
    79801 acagaaacct tatcagcact tggtgaccaa agggtcaaat caacttgttt tccttcttct
    79861 tttaggtcag ctcccagttt gccatcatag ctgtatgtct catctttcag gcgccagctt
    79921 gttttggtag tgaattggtc ggaattgtag ctaacagtat aaggatgttt tgtgtcagag
    79981 aaatctccgc tgtaggtcac tttcttacca gcttcatcga ttgcaacatc ggtaatagtt
    80041 accttgtttc ctaggtgatt agtgatgttg gagtgtttga ggatatcttc ttttttagca
    80101 ccgacaagtg ttgaaaagct actttcaatg ctagaagtgc ctacgtgttg ggctcctgtc
    80161 atacggatat catggacata gtatggattt gtgtaaatcg attcatcatc gtcttttagg
    80221 aaaatttggc tatgattttt caaatctgtg aacttataat tttctttacg gattttcacg
    80281 tcgtctcctt gtttgctctc atctagtaat aaaaatccaa attctcttgc ggcttcatta
    80341 agaggaatgt cgatatagcg gccatatttg cctgtagccg taaagtctgt tccgtcaggc
    80401 cattgagcgc tacttggatt ttttacatct ccccagtacc agagagattt cttgtcatag
    80461 ttgccatctg tgcggtagta gttgacgcga acagttcctg caggctgtgg ctcgtaagag
    80521 aaaaccttgt aatcttggtc taaccaagct tcgttcattt ttggaactag tttttctaca
    80581 gatttatcgc cggttagatt ttttccagct gtattgttga tgaggaagct aattttcttg
    80641 gcttgttctc cctttaattt gacatctagg taatagccgt agtcatcttt cttggcatcc
    80701 ttgaaggaca aagctccgtt tggccagttt tcagatggtt tttcaacatc gtcccaagtc
    80761 catagtcctt gagcatcctt gttttcttca ggaagttttt tgacatggat acggaagtag
    80821 ttatcttcga tgggctcttc tgccttagtt tcagttgtta ctggactagt agaagtagtt
    80881 ggctctgttg caggtttttc ttctgttttc tctagggaag cgtttgcatt tctaggtgaa
    80941 gaaatatcac tttcgttctt accagagcca gctgctgtat cagtaagagg ttgggcaagg
    81001 gtggttgtat ttctgttgtt gggttcgtta gtggttggtg tactttcgtc ggatgagata
    81061 gttggtgtag ccatggcaag caagacaagg cttgcgccga taaggacaga accagttcca
    81121 tttttgaggg aacggatgct gtagaccatt tttttctcag tgtgagatgg tgtttttctc
    81181 ataatgattc tccaatcaat aaatttctat atcagtatag catgtagtaa aacaatatgc
    81241 aagcgttttc tttgatttgt gaaaaaaatt cttacttttg agaagttttc tgtactattt
    81301 tatatatcag tataaatgac ggagataaaa atgtcacata agccaagccg tattattagg
    81361 aagatgatgt gttcccagct atttttattc agaaattgat ctctaacatt accaataaaa
    81421 aagaaaaata tcttgacaag caagggaaaa ttttgttaca ataatagacg gtacttttta
    81481 cttttggtct ctcaagagtg tacagggacg tgctgacaaa tgttgcaaaa gtacacacag
    81541 atgatatctg tcaccaagtg tatcatcacc aaaaataaaa aaacacagga gaatgtagat
    81601 gcctacaatt aaccaattgg ttcgcaaacc gcgtaaatca aaagtagaaa aatctaaatc
    81661 accagctttg aacgttggtt acaatagtca taaaaaagtt caaacaaacg tttcttcacc
    81721 acaaaaacgt ggtgttgcaa ctcgtgttgg aacaatgaca cctaaaaaac ctaactcagc
    81781 ccttcgtaaa ttcgctcgtg tacgtttgag caaccttatc gaagttactg cctacatccc
    81841 aggtatcgga cacaacttgc aggagcacag cgtggtgctt cttcgcggtg gacgtgtaaa
    81901 agaccttcca ggggtacgtt accatatcgt ccgtggtgca cttgatactg caggtgttaa
    81961 cgatcgtaaa caaggccgtt ctaaatacgg tactaaacgt ccaaaagcat aaggaaaggg
    82021 gataaagaga aatgagtcgt aaaaatagag ctccaaaacg tgacgtattg ccagatccgc
    82081 tatacaattc acaactagtt actcgtctta tcaaccgcgt tatgcttgat ggtaaacgtg
    82141 gtactgctgc ttcaatcgtt tacggtgctt ttgagcaaat caaagaagct actggcaacg
    82201 atgcacttga agtatttgaa acagctatgg aaaacatcat gcctgtactt gaagtacgtg
    82261 cacgtcgtgt tggtggttct aactaccaag tcccagttga agttcgtcca gaacgtcgta
    82321 caacacttgg acttcgttgg ttggtaacaa tcgctcgtct tcgtggtgaa cacacaatgc
    82381 aagaccgtct tgcaaaagaa atcttggatg ctgctaacaa cactggtgca gcagttaaga
    82441 aacgtgaaga tactcaccgt atggctgaag ctaaccgtgc attcgcacac ttccgttggt
    82501 aagataggat gcgaaagcgt taagaaagtc ccagagaaaa tagggaatcg aagcaggttg
    82561 cggttgcaac caatgagatt catctttttc tccagacttt tagcttgagc tcaactaaat
    82621 catgatgcta ggaacggtaa ggatgcaagg tgaaaatagg aaactgacgc agtattcgac
    82681 gaatacaagg agttttatct ttttcacgca gcatcccgtt ccagctcaca tcggctaact
    82741 aactttagcc cgggttcaaa ttagctaaat cgattagtat tagctataac tcagcttacc
    82801 atctcgtaag ttgaaaccaa caatagcatg aaaacattga gaacgggtag gtcctgccta
    82861 tccgttttta ttaaaatcgt gttataatag aatagaaatc aaaaataaat aggagaaaca
    82921 aacctcatgg cacgcgaatt ttcacttgaa aaaactcgta atatcggtat catggctcac
    82981 gtcgatgccg gtaaaacaac aactactgag cgtattcttt actacactgg taaaatccac
    83041 aaaatcggtg aaactcacga aggtgcgtca caaatggact ggatggagca agagcaagaa
    83101 cgtggtatca cgatcacatc tgctgcgaca acagctcaat ggaacaacca ccgcgtaaac
    83161 atcatcgaca caccaggaca cgtggacttc acaatcgaag tacaacgttc tcttcgtgta
    83221 ttggatggtg cggttaccgt tcttgactca caatcaggtg ttgagcctca aactgaaaca
    83281 gtttggcgtc aagcaactga gtacggagtt ccacgtatcg tatttgccaa caaaatggac
    83341 aaaatcggtg ctgacttcct ttactctgta agcacacttc acgatcgtct tcaagcaaat
    83401 gcacacccaa tccaattgcc agtcggttct gaagatgact tccgtggtat cattgacttg
    83461 atcaagatga aagctgaaat ctatactaac gaccttggta cggatatcct tgaagaagac
    83521 atcccagctg aataccttga ccaagctcaa gaataccgtg aaaaattgat tgaagcagtt
    83581 gctgaaactg acgaagaatt gatgatgaaa tacctcgaag gtgaagaaat cactaacgaa
    83641 gaattgaaag ctggtatccg taaagcgact atcaacgttg aattcttccc agtattgtgt
    83701 ggttcagcct tcaaaaacaa aggtgttcaa ttgatgcttg atgcggttat cgactacctt
    83761 ccaagcccac ttgacatccc agcaatcaaa ggtattaacc cagatacaga cgctgaagaa
    83821 attcgtccag catctgacga agagccattt gcagctcttg ccttcaagat catgactgac
    83881 ccattcgtag gtcgtttgac attcttccgt gtttactcag gtgttcttca atcaggttca
    83941 tacgtattga atacttctaa aggtaaacgt gaacgtatcg gacgtatcct tcaaatgcac
    84001 gctaacagcc gtcaagaaat cgacactgtt tactcaggtg atatcgctgc tgccgttggt
    84061 ttgaaagata ctacaactgg tgactcattg acagatgaaa aatctaaaat catccttgag
    84121 tcaatcaacg ttccagaacc agttatccaa ttgatggttg agccaaaatc taaagctgac
    84181 caagacaaga tgggtatcgc ccttcaaaaa ttggctgaag aagatccaac attccgcgtt
    84241 gaaacaaacg ttgaaactgg tgaaacagtt atctcaggta tgggtgaact tcaccttgac
    84301 gtccttgttg atcgtatgcg tcgtgagttc aaagttgaag cgaacgtagg tgcgcctcaa
    84361 gtatcttacc gtgaaacatt ccgcgcttct actcaagcac gtggattctt caaacgtcag
    84421 tctggtggta aaggtcaatt cggtgatgtg tggattgaat ttactccaaa cgaagaaggt
    84481 aaaggattcg aattcgaaaa cgcaatcgtc ggtggtgtgg ttcctcgtga atttatccca
    84541 gcggttgaaa aaggtttggt agaatctatg gctaacggtg ttcttgcagg ttacccaatg
    84601 gttgacgtta aagctaagct ttatgatggt tcatatcacg atgtcgactc atctgaaact
    84661 gccttcaaga ttgcggcttc actttccctt aaagaagctg ctaaatcagc acaaccagct
    84721 atccttgaac caatgatgct tgtaacaatc actgttccag aagaaaacct tggtgatgtt
    84781 atgggtcacg taactgctcg tcgtggacgt gtagatggta tggaagcaca cggtaacagc
    84841 caaatcgttc gtgcttacgt tccacttgct gaaatgttcg gttacgcaac agttcttcgt
    84901 tctgcatctc aaggacgtgg tacattcatg atggtatttg accactacga agatgtacct
    84961 aagtcagtac aagaagaaat tattaagaaa aataaaggtg aagactaatc cgtcctcact
    85021 ctagaaggaa gtcacttagt ggcttccttt tgtctttaga aaatacctct aaatatggta
    85081 aaatagtaga agaataatgt gaggaaaatg aatgtcaaat agttttgaaa ttttgatgaa
    85141 tcaattgggg atgcctgctg aaatgagaca ggctcctgct ttagcacagg ccaatattga
    85201 gcgagttgtg gttcataaaa ttagtaaggt atgggagttt catttcgtat tttctaatat
    85261 tttaccgatt gaaatctttt tagaattaaa gaaaggtttg agcgaagaat tttctaagac
    85321 aggcaataaa gctgtttttg aaattaaggc tcggtctcaa gaattttcaa atcagctctt
    85381 gcagtcctac tatagggagg ctttctctga aggtccatgt gctagtcaag gttttaagtc
    85441 cctttatcaa aatttgcaag ttcgtgctga gggtaatcag ctatttattg aaggatctga
    85501 agcgattgat aaggaacatt ttaagaagaa tcatcttcct aatttagcca aacaacttga
    85561 aaagtttggt tttccaactt ttaactgtca agtcgagaag aatgatgtcc tgacccaaga
    85621 gcaggaagag gcctttcatg ctgaaaatga gcagattgtt caagctgcca atgaggaagc
    85681 gctccgtgct atggaacaac tggagcagat ggcacctcct ccagcggaag agaaaccagt
    85741 ctttgatttt caagcgaaaa aagctgcagc taaacccaag ctggataagg cggagattac
    85801 tcctatgatc gaagtgacga cagaggaaaa tcgtctggta tttgaagggg ttgtttttga
    85861 tgtggaacaa aaagtgacta gaacaggtcg tgttttaatc aactttaaaa tgacggacta
    85921 tacttcaagt ttttctatgc aaaagtgggt taaaaacgag gaagaggccc agaagtttga
    85981 cctcatcaag aagaattctt ggctccgagt tcgagggaat gtggagatga ataacttcac
    86041 acgcgatttg attatgaacg tacaggatct gcaggaagtt gttcactatg agcggaagga
    86101 tttgatgcca gaaggtgagc gtcgggttga gtttcatgct catactaaca tgtcgactat
    86161 ggatgctttg ccagaggtcg aagagattgt tgcaacagct gctaagtggg gacacaaggc
    86221 ggttgctatc acagaccatg ggaatgtcca gtcctttcca catggctata aggcggctaa
    86281 gaaagcggga atccagctga tctatgggat ggaagccaat atcgtggagg accgtgtccc
    86341 tatcgtctat aacgaagtgg agatggactt atcagaagca acctacgtgg tctttgacgt
    86401 ggaaacgacg ggactttcag ctatctataa tgacttgatt caggttgcgg cctctaagat
    86461 gtacaagggg aatgttattg ctgaatttga tgaatttatc aatcctgggc atcccttgtc
    86521 agcttttact acagagttaa ctggaattac agatgatcat gtcaaaaatg ccaaaccact
    86581 agaacaagtt ttgcaagaat tccaagaatt ttgcaaggat acggtcctag ttgcccacaa
    86641 tgctaccttt gacgttggct ttatgaatgc taattatgag cgtcatggtc ttccaaagat
    86701 tagtcagcca gttattgata cgctggagtt tgctagaaac ctctatcctg agtataaacg
    86761 ccatggtttg gggcctttga ccaagcgttt tggtgtggcc ttggaacatc atcacatggc
    86821 caactacgat gcggaagcga ctggtcgtct gcttttcatc tttatcaaag aggtagcaga
    86881 aaaacatggt gtgaccgatt tagctagact caacattgat ctaatcagtc cagattctta
    86941 caaaaaagct cggatcaagc atgcgaccat ctatgtcaag aatcaggtag gtctaaaaaa
    87001 tatctttaag ctggtttcct tgtctaatac caagtatttt gaaggagtgc cacggattcc
    87061 gagaacggtt ctagatgccc atcgagaggg cttgatttta ggttcagcct gttcagaggg
    87121 tgaagttttt gacgtggtcg tttctcaagg tgtggatgcg gcggttgagg tggccaagta
    87181 ttatgacttt atcgaggtca tgccaccggc tatctatgcg cccttgattg ctaaagagca
    87241 ggtcaaggat atggaggaac tccagaccat tatcaagagt ttgatagagg ttggagaccg
    87301 ccttggcaag cctgttttgg ctacgggaaa tgttcactat atcgaaccgg aagaagagat
    87361 ttatcgtgaa attatcgtcc gtagtttggg acagggtgcg atgattaacc gaactatcgg
    87421 tcatggtgaa catgcccaac cagcaccact tccaaaggct cattttcgaa cgactaatga
    87481 gatgttggat gaatttgcct ttttgggaga ggaactggct cgtaaactgg ttattgaaaa
    87541 caccaatgcc ttggcagaaa tatttgaacc cgttgaagtc gttaagggtg acttgtatac
    87601 gcctttcatc gacaaggctg aagaaacagt tgctgagttg acctataaga aagcttttga
    87661 gatttatgga aatccgctgc cagatattgt tgatttgcgg attgaaaaag aattaacatc
    87721 catactgggg aatggatttg ctgtgattta tctggcatcg cagatgctgg tgcaacgttc
    87781 taatgaacgg ggttatttgg ttggttctcg tgggtctgtc ggatctagtt tcgttgcgac
    87841 catgattgga attacggagg tcaatcctct ctctcctcac tatgtctgtg gtcagtgtca
    87901 gtacagtgag tttatcacag atggttcgta cggttcagga tttgatatgc cccataagga
    87961 ctgtccaaac tgtggtcaca aactcagtaa aaacggacag gatattccgt ttgagacctt
    88021 ccttggtttt gatggggata aggttcctga tattgacttg aacttctcgg gagaagatca
    88081 gcctagcgcc cacttggatg tgcgtgatat ctttggtgaa gaatatgcct tccgtgcggg
    88141 aacagttggt acggtagctg ccaagactgc ctatggattt gtcaagggtt acgagcgaga
    88201 ttatggcaag ttttatcgtg atgcagaagt agaacgcctc gctcaaggag cggcgggtgt
    88261 caagcggaca acaggccaac acccgggggg aatcgttgtt attccgaact acatggatgt
    88321 ctacgatttt acgcctgtcc agtatccagc agatgatgtc acggctgaat ggcagaccac
    88381 tcactttaac ttccacgata tcgatgagaa cgtcctcaaa ctcgatgtac tgggacatga
    88441 tgatccgacc atgattcgaa aacttcagga tttgtctggt attgacccta ataaaattcc
    88501 tatggatgac gaaggcgtga tggcactctt ttctgggact gatgtgctag gggtaacacc
    88561 tgaacaaatt ggaacgccta cgggtatgtt ggggattcca gagtttggaa caaatttcgt
    88621 acgtggaatg gtagacgaaa cccatccgac aacctttgcg gaattgcttc agctgtctgg
    88681 tctgtcccac ggtactgatg tttggttggg gaatgctcag gatctgatta agcaaggaat
    88741 agcggaccta tcgactgtta tcggttgtcg ggacgacatc atggtttacc tcatgcatgc
    88801 gggtctggaa cctaagatgg cctttaccat tatggaacgg gtacgtaagg gtttgtggct
    88861 aaagatttca gaagaggaga gaaatggcta tatcgaagca atgaaggcta ataaggtgcc
    88921 agagtggtat atcgaatcct gtgggaaaat taagtacatg ttccctaagg cccatgcggc
    88981 agcctacgtt atgatggcct tgcgtgtagc ttacttcaag gttcaccatc ctatttatta
    89041 ctactgtgct tacttctcca ttcgtgctaa ggcttttgat atcaagacca tgggtgcggg
    89101 cttggaggtc atcaagcgca gaatggaaga aatctctgaa aaacggaaga acaatgaagc
    89161 ctctaatgtg gaaatcgatc tctatacaac tcttgagatt gtcaatgaga tgtgggaacg
    89221 aggtttcaag tttggtaaat tagatctcta ccgtagtcag gcgacagagt tcctcatcga
    89281 cggggatacc cttatcccac catttgtagc aatggatggt ctgggagaga acgttgccaa
    89341 gcaactggtg cgggcgcgtg aagagggaga attcctctct aaaacagaac tacgcaagcg
    89401 tggtggactc tcatcaacct tggttgaaaa gatggatgag atgggtattc ttggaaatat
    89461 gccagaggat aaccagttga gtttgtttga tgagttgttt taaaaaattg cttaataatc
    89521 tattaaaaga ggctaacgta tatccaatag atttacatta gctttctttt ttgttaaaat
    89581 agtctatgga aagagggtga gagtatgtca aagatgagta taagcatccg tctggatagt
    89641 gaggttaagg agcaggccca acaggtgttt agtaatctgg gaatggatat gacaacagct
    89701 attaatattt tccttcgtca ggcaattcaa tatcagggat taccttttga tgttagacta
    89761 gacgaaaatc ggaagttgct ccaagcgtta acggatttag accaaaatcg taatatgagc
    89821 cagtcttttg aatcagtctc agatttgatg gaggacttac gtgcttaaga ttcgttatca
    89881 taaacagttt aaaaaagatt ttaagttggc tatgaagcgt ggtttgaagg cagaattatt
    89941 agaagaagtt ttgaattttc tggttcaaga aaaagaacat cctgccagat atcgtgatca
    90001 ttcattgacg gcatccaagc attttcaagg agttcgtgaa tgccataccc agccagattg
    90061 gcttttggtt tataaagtag acaagtcgga attgatttta aatttgctga ggacaggcag
    90121 tcacagtgat ttattttaat ctattttaag ggggttctca tgaaactaag aatatttgcg
    90181 gaagataagc cggctaagaa ggtatttgaa tatcaattag aacttgctga tcgtacaatt
    90241 cttctatcga cagcactctt gtcaggtgct attgctttag caggaatctt ttctgctttg
    90301 aaagaaaaat aaaaatagaa aagagaaaac agaatggttt taccaaattt taaagaaaat
    90361 ctagaaaaat atgcgaaatt gttggttgcg aacggaatta acgtgcaacc tggtcacact
    90421 ttggctctct ctattgatgt ggagcaacgt gaattggcac atctaatcgt gaaagaagct
    90481 tatgccttgg gtgcgcatga ggtcatcgtt cagtggacag atgatgtgat taaccgtgag
    90541 aaattcctcc atgccccgat ggagcgtttg gacaatgtgc cagaatacaa gattgctgag
    90601 atgaactatc ttttggagaa caaggctagc cgtcttgggg ttcgttcatc tgatccaggt
    90661 gccttgaacg gagtggacgc tgacaagctt tcagcttctg ctaaagctat gggacttgcc
    90721 atgaagccta tgcgtatcgc aactcaatct aacaaggtta gctggactgt agcagccgct
    90781 gctggacttg agtgggctaa gaaagtcttc ccaaatgctg cgagcgacga agaagcagtt
    90841 gatttccttt gggatcaaat cttcaaaact tgtcgtgtct acgaagcaga tcctgttaag
    90901 gcttgggagg aacatgcagc cattctcaag agcaaggccg atatgcttaa taaggagcaa
    90961 ttttcagccc ttcactacac agcgccagga acagatttaa cacttggttt gccaaagaac
    91021 cacgtttggg aatcagctgg tgctgtcaat gcacagggcg aagaattctt gccaaatatg
    91081 ccgacagaag aggtcttcac agcgcctgac ttccgtcgtg cagatggtta tgtcacttct
    91141 acaaaaccgc ttagctacaa cggaaatatc attgaaggca ttaaggtgac ctttaaggat
    91201 ggacaaatcg tagatatcac tgctgagaag ggtgatcagg ttatgaaaga ccttgtcttt
    91261 gaaaatgcgg gtgcgcgtgc cttgggtgaa tgtgccttgg taccagatcc aagtccaatt
    91321 tctcagtcag gcattacctt ttttaacacc cttttcgatg aaaatgcgtc aaaccacttg
    91381 gctatcggtg cagcctatgc gactagcgtt gttgatggag cggagatgag cgaagaggag
    91441 cttgaagctg cagggcttaa ccgttcagat gttcacgtag actttatgat tggttctaac
    91501 caaatggata tcgatggtat tcgtgaggat ggaacgcggg tacctctttt ccgtaatggg
    91561 aattgggcaa attaaggaga taatatgtta ggaagtatgt tcgttggtct cctagtggga
    91621 tttttagcag gtgctatgac caatcgtgga gagcgaatgg gatgttttgg aaaaatgttt
    91681 ctcggttgga tcggagcctt tctaggtcac ttgctctttg gaacttgggg gccagtttta
    91741 tcaggaacag ctattatccc agcgatttta ggagccatga ttgttttagc tattttttgg
    91801 agacgaggaa gttaatttcc taaatctgat actcaatgaa aatcaaagag caaactagga
    91861 aactagccgc aggttgctca aagcactgct ttgaggttgc agatagaact gacgaagtca
    91921 gctaaaaaca ctgttttgag gttgcagata gaactgacga agtcagtaac atatatacgg
    91981 caaggcgacg ttgacgcggt ttgaagagat ttttgaagag tatgaaacga aaaggaggtt
    92041 ggtcattgta ctagcctcct tttgatatga tataatagtt ctatgagatt agataaattt
    92101 ttagttgcct gtgcggtggg aagtcggact gaggtcaaaa acttgctcaa ggctgggcgc
    92161 gtgactgtaa atggtaaaaa agaaaaatca gctaaattgc agattgatga aaaaatagat
    92221 gagattcgct ttgatgggca agtgttggag tatgaagagt ttgtctacta catgatgaac
    92281 aagcccaaag gagttatctc agcgactgag gatcccaagc acagaaccgt tctggacttg
    92341 ttggatgact tggcgcggag taaggaagtt tttccagtag gacgcttgga tattgacacg
    92401 catggtcttt tgctcttgac caataatggt cagctggctc atgttcttct ttcgcccaag
    92461 cgtcatgtgg acaagactta tcaggctcag gtcaagggaa ttatgaccca agaagatgtg
    92521 gagacattta tcaagggcat tccgctcaaa gactttacct gtcagcccgc tagactggag
    92581 attctttcca cagatgcaga aaagaatcag agccaaatcc gtgtgaccat tgcagaaggg
    92641 aagtttcatc agatcaagcg tatggtgggc tactgtggca aggaagtggt ggacttgcaa
    92701 cgattgacta tgggaacttt agtattagat gagaacctgg aacgagggga atggcgtcgc
    92761 ttgaccaagg aagaattaga aattctccgc gctaatatta tttaatttag t
//
LOCUS       DBEJHE010000004        91458 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC4 isolate 671759
            SAMN38261586-rid24793303.denovo.04, whole genome shotgun sequence.
ACCESSION   DBEJHE010000004 DBEJHE010000000
VERSION     DBEJHE010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261586
            Sequence Read Archive: SRR26833752
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 91458)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 91458)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576136.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576136.1
            Genome Coverage       :: 109x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 19:48:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,067
            CDSs (total)                      :: 2,029
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 131
            CDSs (without protein)            :: 131
            Pseudo Genes (ambiguous residues) :: 0 of 131
            Pseudo Genes (frameshifted)       :: 64 of 131
            Pseudo Genes (incomplete)         :: 59 of 131
            Pseudo Genes (internal stop)      :: 46 of 131
            Pseudo Genes (multiple problems)  :: 32 of 131
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..91458
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261586-rid24793303.denovo.04"
                     /strain="GPSC4"
                     /isolate="671759"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            <1..3071
                     /locus_tag="ACL3EZ_000379"
     CDS             <1..3071
                     /locus_tag="ACL3EZ_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078464109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005576 - extracellular region [Evidence
                     IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HGR0392013.1"
                     /translation="ASASASTSASASASTSASESASTSASASASTSASESASTSASAS
                     ASTSASVSASTSASASASTSASASASTSASESASTSASASASTSASASASTSASESAS
                     TSASASASTSASASASTSASESASTSASESASTSASASASTSASASASTSASASASTS
                     ASASASTSASASASTSASASAGKSRQQLPNTGTEVSKSSVASTSASESASTSASASAS
                     TSASASASTSASESASTSASASASTSASASASTSASASASTSASASASTSASASASTS
                     ASASASTSASASASTSASASASTSASESASTSASASASTSASASASTSASASASTSAS
                     ASASTSASASASTSASALASTSASASASTSASASASTSASESASTSASASASTSASES
                     ASTSASASASTSASASASTSASASASTSASASASTSASASASTSASASASTSASESAS
                     TSASASASTSTSASESASTSASASASTSASASASTSASASASTSASASASTSASTSAS
                     TSASESASTSASASASTSASASASASTSASVSASTSASESASTSASASASTSASESAS
                     TSASALASTSASASASTSASASASTSASASASTSASESASTSASASASTSASVSASTS
                     ASASASTSASESASTSASASASTSASASASTSASASASTSASASALTSASESASTSAS
                     ASASTSASASASTSASASASTSASASASTSASASASTSASTSASTSASASASTSASAS
                     ASTSASASASTSASASASTSASASASTSASASASTSASASASTSASASASTSASESAS
                     TSASASASTSASVSASTSASASASTSASASASTSASASASTSASASASTSASASASTS
                     ASASASTSASASASTSASASASTSASASASTSASESASTSASASASTSASASASTSAS
                     ESASTSASASASTSASASASTSASASASTSASESASTSASASASTSASASASESASTS
                     ASASTSAGKSRQQLPNTGTEASKSSVLLGALAAVTGLGLFAKRRKRDDEE"
     gene            3073..4518
                     /locus_tag="ACL3EZ_000380"
                     /pseudo
     CDS             3073..4518
                     /locus_tag="ACL3EZ_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000341103.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
     gene            4515..5393
                     /locus_tag="ACL3EZ_000381"
     CDS             4515..5393
                     /locus_tag="ACL3EZ_000381"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0120225 - coenzyme A binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
                     /protein_id="HGR0392014.1"
                     /translation="MKKNHLVGDALILTVSDQIEELDYLLESLSNICFHIAAPVQFSE
                     KIRSLETNYNVRLRTITNEEQLNFLVDTCDFLLDINHFQEVDAIVSKFVQAGKSVFAF
                     DNTVHGNQGQEVFLSSTPDKLVSRVRDYLNEVRVGTNHQEKIIQDGTWNVFKIDDKAH
                     FIVGANVACRNFENFHVSSGKLILNNGVFINNSCSFNCMERIEIGAGTMMGEGVRFYD
                     HDHIYTAEKIEKWQWTTAPIRVGRDCWIGSNVTILKGVTIGDNTIIGAGCLIRNDIPS
                     NSVVYNNGNLFVKMRV"
     gene            5750..6964
                     /locus_tag="ACL3EZ_000382"
     CDS             5750..6964
                     /locus_tag="ACL3EZ_000382"
                     /EC_number="2.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HGR0392015.1"
                     /translation="MYRKVIALGADIHYLDKVETVIKSVSVHNHEVKFYVFNDDLPSE
                     WFLLMRNRLKVIGSEIINVKKADHNLRDFHLPNAILSYATFFRYFIADEVLEDRVLYL
                     DSDIIVNANLDELFFLDLQGYAIAAVQDFDQDGWLTTFNSGMLLIDAKKWREKKSTQN
                     LLELTAQHHEHVYGDQGVLNIYFGDQWLHLDKEYNFMVGLDQFLHLKGNADWYQSNYY
                     GNYEPKIVHYTTEFKPWTHLTLTRFRKLWWFYYGLNWNDVLLSSDIVKRSFKELVGVP
                     LYHTCIFTNSAAMESLEYLLSELPEVHFTILAHTNFAPSVVDLQRYLNLSLFPNFNSF
                     NMKETLDKMDFYLDINHEGEIVNIIEEVCRRNKPIFSFDNTSHDSKGRSRIFSATEPD
                     KMVDAIRKFLGE"
     gene            6969..7844
                     /locus_tag="ACL3EZ_000383"
     CDS             6969..7844
                     /locus_tag="ACL3EZ_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000426741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HGR0392016.1"
                     /translation="MENELISIVVPIYNVENYLRMCLDSIQNQTYQNFECLLINDGSP
                     DHSSKICEEFVEKDSRFKYFEKANGGLSSARNLGIECSGGAYITFVDSDDWLEHDALD
                     RLYGALKKENADISIGRYNSYDETRYVYMTYVTDPDDSLEVIEGKAIMDREGVEEVRN
                     GNWTVAVLKLFKRELLQDLPFPIGKIAEDTYWTWKVLLRASRIVYLNRCVYWYRVGLS
                     DTLSNTWSEKRMYDEIGAREEKIAILASSDYDLTNHILIYKNRLQRVVAKLEEQNMQF
                     TEIYRRMMEKLSLLP"
     gene            7873..8883
                     /locus_tag="ACL3EZ_000384"
     CDS             7873..8883
                     /locus_tag="ACL3EZ_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HGR0392017.1"
                     /translation="MKLHLTNLYGMAGDSTVILAQNAVQKIASQLGFREVGIYFYNIA
                     SDSPSEMNKRLDGIMASISIGDILVFQSPTWNGFEFDRLLFDKLKDMQVKIICFIHDV
                     VPLMFDSNYYLMKDYMYMYNLSDVLIVPSERMKTRLMEEGLTTKKILVQGMWDHPHDL
                     SLYTPAFKKRTFFAGSLERFPDLQNWSQDTPLRVFSNKGEAGSSARNLSIEGWKKDEE
                     LLLELSKGGFGLVWGTHQNEGESNQYYTLNISHKVSTYLTAGIPVIVPSNLSTAKFIV
                     DQGLGFVANSLEEVHEIVDKMNLQEYQEMTNRIKTFSYLLKEGYFTKKLLVDAIYHLG
                     VE"
     gene            8893..11346
                     /locus_tag="ACL3EZ_000385"
     CDS             8893..11346
                     /locus_tag="ACL3EZ_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001044150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_1767 family glycosyltransferase"
                     /protein_id="HGR0392018.1"
                     /translation="MIKTIVLAGNRNYTRQLETTIKSILYHNRDVKIYILNQDIMPDW
                     FRKPRKIASMLGSEIIDVKLPEQTVFQDWKKQAHISSIAYARYFIPDYIQEDTVLYLD
                     CDLLINDKLDSLFEQDVREHYIAAIRDANGQGFNTGVLLINNEKWRQEKLKERLIEQS
                     IVTMKEVEEGRFEHFNGDQTIFNQVLQDDWLELGRAYNLQVGHDIVALYNNWQEHLAF
                     NDKPVVIHFTTYRKPWTTLTANRYRDLWWEFHDLEWNQILQHHLGEFELISPLDKEFS
                     CLTLTNSQDLEGIEELVTALPEVVFHIAAWTDMGDKLKKLAVYNNVRLHPQIVPPVLD
                     KLKKSTNLYLDINHGSADENFLKSLQEQEKTLLAFQSTQHGELGQIVFENGKVSFMID
                     TIKDFKKNGHLTCFRQLPSLTCLTFTASQDIEQLDYLAGQLPNVVFQVAAWTAMGPKL
                     YDLSNRYPNIQLYPAISRDKLDELKEKMDAYLDINLLTSTSDIVAEMAHLSKPILAFY
                     KSQNGNNGQRLYSSEHPERMLADLQKLITKDMLEKPLDIIQVKGIDETLDYIIEHNSS
                     LVRFGDGEVNLMWGLPIPYQNHDLELANQLKHIVGLESDEKLVVCLPDAFDDRFVFTW
                     WATPFWKEHMNVYMDFYKELCKGSWYGSTFISRPYIDYEDKSKAKGQFEKLKSIWENR
                     DILIVEGITSRSGVGNDLFDKVKSVKRIICPSHNAYSVVDNIQEEIMKHAEGRLILCM
                     LGPTAKVLAYHLSRKGYQVLDIGHIDSEYEWMKMGAKTKVKFSHKHTAEYNFDQDIQF
                     IEDETYNSQILVDLSKREV"
     gene            11343..12227
                     /locus_tag="ACL3EZ_000386"
     CDS             11343..12227
                     /locus_tag="ACL3EZ_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HGR0392019.1"
                     /translation="MKDLISVIVPVYNVEPFISSCLDSLSKQIYQNFEVLLVNDGSTD
                     NSGAICREYADRDSRFHYFEKENAGVADARNFGIERSKGDYITFVDSDDWVTEEYLSI
                     LIETLKEQHSEIVVSTYSTYNESDGLFYIYVFDSDYYVKNYNSKLLMEELPLLERYDM
                     SFLTSWGILFKRELFQEVQFPFGRVCEDIGTNYKLFMQVEKVTYINKVLYWYRVGKEG
                     LSNSYSPKMMRDDCDFRLERIAVLALKGYDVSKYLDQMKFYLKYRHDIAIQRELKENV
                     ETRHLEMLDYLLNGNKYN"
     gene            12252..13472
                     /locus_tag="ACL3EZ_000387"
     CDS             12252..13472
                     /locus_tag="ACL3EZ_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000938701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HGR0392020.1"
                     /translation="MLQDKKSVVFAGDYAYIRQIETAMKSLCRHNSHLKIYLLNQDIP
                     QEWFSQIRIYLQEMGGDLIDCKLIGSQFQMNWSNKLPHINHMTFARYFIPDFVTEDKV
                     LYLDSDLIVTGDLTDLFELDLGENYLAAARSCFGAGVGFNAGVLLINNKKWGSETIRQ
                     KLIDLTEKEHENVEEGDQSILNMLFKDQYSSLEDQYNFQIGYDYGAAAFKHQFIFDIP
                     LEPLPLILHYISQDKPWNQFSVGRLREVWWEYSLMDWSVILNEWFSKSVKYPSKSQIF
                     KLQCVNLTNSWCVEKIDYLAEQLPEVHFHIVAYTNMANELLALTRFPNVTVYPNSLPM
                     LLEQIVIASDLYLDLNHDRKLEDAYEFVLKYKKPMIAFDNTCSENLSEISYEGIYPSS
                     IPKKMVAAIRSYMR"
     gene            13481..14677
                     /locus_tag="ACL3EZ_000388"
     CDS             13481..14677
                     /locus_tag="ACL3EZ_000388"
                     /EC_number="2.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HGR0392021.1"
                     /translation="MRKSIVLAADNVYLIPLETTIKSVLYHNRDVDFYILNSDIAPEW
                     FKLLGRKMEVVNSTIRSVHIDKELFESYKTGPHINYASYFRFFATEVVESDRVLYLDS
                     DIIVTGELATLFEIDLKGYSIGAVDDVYAYEGRKSGFNSGVLLMDVAKWKEHSIVNSL
                     LELAAEQNQVVHLGDQSILNIYFEDNWLALDKTYNYMVGVDIYHLAQECERLDDNPPT
                     IVHYASHDKPWNTYSISRLRELWWVYRDLDWSEIAFQRSDLNYFERSNQSKKQVMLVT
                     WSADIKHLEYLVQRLPDWHFHLAAPCDCSEELTSLSQYTNVTVYQNVLHSRIDWLLDD
                     SIVYLDINTGGEVFNVVTRAQESGKKIFAFDITRKSMDDGLYDGIFSVERPDDLVDRM
                     KNIEIE"
     gene            14677..14901
                     /locus_tag="ACL3EZ_000389"
     CDS             14677..14901
                     /locus_tag="ACL3EZ_000389"
                     /inference="COORDINATES: protein motif:HMM:NF025025.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HGR0392022.1"
                     /translation="MSELISVVVPIYNTGKYLVECVEHILKQTYQNIEIILVDDGSTD
                     NSGEICDAFMMQDNRVRVLHQENKGGGSTS"
     gene            14906..15583
                     /locus_tag="ACL3EZ_000390"
     CDS             14906..15583
                     /locus_tag="ACL3EZ_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HGR0392023.1"
                     /translation="MGISVAKGEYITIVDSDDIVKENMIETLYQQVQEKDADVVIGNY
                     YNYDESDGNFYFYVTGKDFCVEELAIQEIMNRQAGDWKFNSSAFILPTFKLIKKELFN
                     EVHFSNGRRFDDEATMHRFYLLASKIVFINDNLYLYRRRSGSIMRTEFDLSWARDIVE
                     VFSKKISDCVLAGLDVSVLRIRFVNLLKDYKQTLEYHQLTDTEEYKDICFRLKLFFDA
                     EQRNGKS"
     gene            15640..16857
                     /gene="secY2"
                     /locus_tag="ACL3EZ_000391"
     CDS             15640..16857
                     /gene="secY2"
                     /locus_tag="ACL3EZ_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system protein translocase subunit
                     SecY2"
                     /protein_id="HGR0392024.1"
                     /translation="MTKIYSSIAVKKGLFTLFLLFIYVLGSRITLPFVDLNTKDFLGG
                     STAYLAFSAALTGGNLRSLSIFSVGLSPWMSAMILWQMFSFSKRLGLTSTSIEIQDRR
                     RMYLTLLIAVIQSLAVSLSLPVQSSYSVILVALMNTLLLIAGTFFLVWLSDLNASMGI
                     GGSIVILLSSIVLNIPQDVIETFKLVYIPTGIVVLLVFMTIIFSYLLALMYRARYLVP
                     VNKIGLHNRFKRYSYLEIMLNPAGGMPYMYVMSFLSVPAYLFILLGFIFPNHSGLAAL
                     SKEFMVGKPLWVYVYISVLFLFSIIFAFVTMNGEEIADRMKKSGEYIYGIYPGADTSR
                     FINRLVLRFSVIGGLFNVIMAGGPMLFVLFDEKLLRLAMIPGLFMMFGGMIFTIRDEV
                     KALRLNETYRPLI"
     gene            16867..18447
                     /gene="asp1"
                     /locus_tag="ACL3EZ_000392"
     CDS             16867..18447
                     /gene="asp1"
                     /locus_tag="ACL3EZ_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006886 - intracellular protein transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system protein Asp1"
                     /protein_id="HGR0392025.1"
                     /translation="MYYFIPAWYGSERTWHADITPWYFSHFRLEFDDTFHQIRLFQEQ
                     DIDSRLLVLAYQPHLRYFLYRHGVLETDTYSVFDVMQDFHNLHTQVLSIRDIEWDDDC
                     EFIYSPFTIIVQKNGKKFAKVEHGVEGFISDIQYFGPNGQIHMHHIMDDRGFISSIIF
                     FEDGQAAYQEYLNPKGVWQFRERLKEGGQVEVNPILGYRFKMLTYQNMGDLVAEFFEN
                     YLQTYVKDQDIFMLPSHSHHDQLVLDRLPSTNPKLLSLFIGRNPQDTFRDLDVTFEKS
                     DLILVDREDSLRLLQELYPERMHQCYHLSSFDTRLRLGRSQTKKESIIYFQLDFEQGI
                     DNQALLQVLSFVAENKDTEVIFGAFAASQEQMNEVEGIVESFIQENIQSENLGKAIDY
                     GDAENPLEENQHQDLRLQFVNLNDELDLIKTLEFVRLIVDLNRHPHLYTQIAGISAGI
                     PQINLVETVYVEHLKNGYLLADVTEFSKAAHYYTDRLKEWNESLIYSIDKIKEHTGQQ
                     FLGKLEKWIEEVKNVKGT"
     gene            18431..19966
                     /gene="asp2"
                     /locus_tag="ACL3EZ_000393"
     CDS             18431..19966
                     /gene="asp2"
                     /locus_tag="ACL3EZ_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006886 - intracellular protein transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system protein Asp2"
                     /protein_id="HGR0392026.1"
                     /translation="MSKELNILQIGLANWENHYDIPENMSWYYFYPNSSKALREIIEK
                     EDINRFHAVLIEDGQYSRDLFSYVKYFEPYTLFYNQNLQINDREVVDFLKKRCAQAID
                     FLSPQQLINDLSKSLFGGGYGDKLFPPTIQVNPNFTGAISYQGLDYVSLEGEFGQDFA
                     QLAYWAYNIMVQKTLPIELWLEYEKEGNCDFRLVIRKMWSGSVDDFFEEVIVSEKDLE
                     QALFMDSRDGDYFLSISVEARGRGTIKLGNLHQRWSRKQFGKFVLGGNILHDSKRDEI
                     NYFFHPGDFKPPLTVYFAGYRPAEGFEGYFMMKTLGCPFILFSDPRLEGGAFYLGTDE
                     LEGKVKDTITHYLDYLGFDHKDLILSGLSMGTFPALYYGASFEPHAIIVGKPLANLGT
                     IASRGRLDAPGVSNLAFDCLIHHTGGTSSQDMTELDQRFWKIFKQANFSKTTFGLSYM
                     KDEEMDPQAYEQLVSYLCNTGAKILSKGTAGRHNDDTDTNISWFLHFYRMVLETGFGR
                     EKR"
     gene            19963..20403
                     /gene="asp3"
                     /locus_tag="ACL3EZ_000394"
     CDS             19963..20403
                     /gene="asp3"
                     /locus_tag="ACL3EZ_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006886 - intracellular protein transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system protein Asp3"
                     /protein_id="HGR0392027.1"
                     /translation="MIITQRQSIHWGEVGGTYMYGTTVSYYPDKSVRLYNPLLPSGEI
                     LKTWFSSVNYQAARTQPQLPLLKRKQEYQLSLVFDCQPENGVYTKITFFDRYGDILEK
                     KVEKVKDFIFTYPEDSYTYQVSLLSAGFESLTFYHFSIKEIRSV"
     gene            20396..22768
                     /gene="secA2"
                     /locus_tag="ACL3EZ_000395"
     CDS             20396..22768
                     /gene="secA2"
                     /locus_tag="ACL3EZ_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system translocase SecA2"
                     /protein_id="HGR0392028.1"
                     /translation="MFRRLGQDFQLRKVKKILKQINALKGKMSSLSDQELVAKTVEFR
                     QRLSEGESLDDILVEAFAVVREADKRILGMFPYDVQVMGAIVMHYGNVAEMNTGEGKT
                     LTATMPVYLNAFSGEGVMVVTPNEYLSKRDAEEMGQVYRFLGLTIGVPFTEDPKKEMK
                     AEEKKLIYASDIIYTTNSNLGFDYLNDNLASNEEGKFLRPFNYVIIDEIDDILLDSAQ
                     TPLIIAGSPRVQSNYYAIIDTLVTTLVEGEDYIFKEEKEEVWLTTKGAKSAENFLGID
                     NLYKEEHASFARHLVYAIRAHKLFTKDKDYIIRGNEMVLVDKGTGRLMEMTKLQGGLH
                     QAIEAKEHVKLSPETRAMASITYQSLFKMFNKISGMTGTGKVAEKEFIETYNMSVVRI
                     PTNRPRQRIDYPDNLYITLPEKVYASLEYIKQYHAKGNPLLVFVGSVEMSQLYSSLLF
                     REGIAHNVLNANNAAREAQIISESGQMGAVTVATSMAGRGTDIKLGKGVAELGGLIVI
                     GTERMESQRIDLQIRGRSGRQGDPGMSKFFVSLEDDVIKKFGPSWVHKKYKDYQVQDM
                     TQPEVLKGRKYRKLVEKAQHASDSAGRSARRQTLEYAESMNIQRDIVYKERNRLIDGS
                     RDLEDVVVDIIERYTEEVAADHYASRELLFHFIVTNISFHVKEVPDYIDVTDKTAVRS
                     FMKQVIDKELSEKKELLNQHDLYEQFLRLSLLKAIDDNWVEQVDYLQQLSMAIGGQSA
                     SQKNPIVEYYQEAYAGFEAMKEQIRADMVRNLLMGLVEVTPKGEIVTHFP"
     gene            22780..24291
                     /gene="gtfA"
                     /locus_tag="ACL3EZ_000396"
     CDS             22780..24291
                     /gene="gtfA"
                     /locus_tag="ACL3EZ_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system glycosyltransferase GtfA"
                     /protein_id="HGR0392029.1"
                     /translation="MTIYNINLGIGWASSGVEYAQAYRAGVFRKLNLSSKFIFTDMIL
                     ADNIQHLTANIGFDDNQVIWLYNHFTDIKIAPTSVTVDDVLAYFGGEESHREKNGKVL
                     RVFFFDQDKFVTCYLVDENKDLVQHAEYVFKGNLIRKDYFSYTRYCSEYFAPKDNVAV
                     LYQRTFYNEDGTPVYDILMNQGKEEVYHFKDKIFYGKQAFVRAFMKSLNLNKSDLVIL
                     DRETGIGQVVFEEAQTAHLAVVVHAEHYSENATNEDYILWNNYYDYQFTNADKVDFFI
                     VSTDRQNEVLQEQFAKYTQHQPKIVTIPVGSIDSLTDSSQGRKPFSLITASRLAKEKH
                     IDWLVKAVIEAHKELPELTFDIYGSGGEDSLLRDIIANHQAEDYIQLKGHAELSQIYS
                     QYEVYLTASTSEGFGLTLMEAIGSGLPLIGFDVPYGNQTFIEDGQNGYLIPSSSDHVE
                     DQIKQAYAAKICQLYQENRLEAMRAYSYQIAEGFLTKEILEKWKKTVEEVLHD"
     gene            24284..25621
                     /gene="gtfB"
                     /locus_tag="ACL3EZ_000397"
     CDS             24284..25621
                     /gene="gtfB"
                     /locus_tag="ACL3EZ_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0031647 - regulation of protein stability
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system glycosylation chaperone
                     GtfB"
                     /protein_id="HGR0392030.1"
                     /translation="MIELYDRYSHESRDLHESLVATGLSQLGVVIDADGFLPDGLLSP
                     FTYYLGYEDGKPLYFNQVPVSDFWEILGDNQSACIEDVTQERAVIHYVDGMQARLVKQ
                     VDWKDLEGRVRQVDHYNRFGACFAKTTYSADSEPIMTVYQDVNGQQVLLENHVAGDIL
                     LTLPGQSMRYFANKVEFITFFLQDLEIDTSQLIFNTLATPFLVSFHHPDKSGSDVLVW
                     QEPLYDAIPGNMQLILESDNVRTKKIIIPNKATYERALELTDEKYHDQFVHLGYHYQF
                     KRDNFLRRDALILTNSDQIEQVEAIAGALPDVTFRIAAVTEMSSKLLDMLRYPNVVLY
                     QNASPQKIQELYQLSDIYLDINHSNELLQAVRQAFEHNLLILGFNQTVHNRLYIAPDH
                     LFESSEVAALVETIKLALSDVDQMRQALGKQGQHANYVDLVRYQETMQTVLGG"
     gene            25623..25802
                     /gene="asp4"
                     /locus_tag="ACL3EZ_000398"
     CDS             25623..25802
                     /gene="asp4"
                     /locus_tag="ACL3EZ_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory secretory system protein Asp4"
                     /protein_id="HGR0392031.1"
                     /translation="MSEEDLFYKDVEGRMEELKQKPIKKEKETRGEKISKTFSLLLGL
                     MILIGLLFTLLGILR"
     gene            25807..26031
                     /locus_tag="ACL3EZ_000399"
     CDS             25807..26031
                     /locus_tag="ACL3EZ_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory secretory protein Asp5"
                     /protein_id="HGR0392032.1"
                     /translation="MIEILIVLAIILSLALIVLVTIQPRQNQLFSMDATSNIGKPSYW
                     QSNTLVKVLTLLVSLALFVLLLTFMVITYK"
     gene            complement(26267..27220)
                     /locus_tag="ACL3EZ_000400"
     CDS             complement(26267..27220)
                     /locus_tag="ACL3EZ_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HGR0392033.1"
                     /translation="MSISQRTTKLILATCLACLLAYFLNLSSAVSAGIIALLSLSDTR
                     RSTLKLARNRLFSMLLALAIGVLAFHLSGFHIWSLGLYLAFYVPLAYKMGWEIGITPS
                     TVLVSHLLVQESTSPDLLVNEFLLFAIGTGFALLVNLYMPSREEEIQHYHTLVEEKLK
                     DILQRFKYYLSRGDGRNRAQLVAELDTLLKEALRLVYLDHSDHLFHQTDYHIHYFEMR
                     QRQSRILRNMAQQINTCHLAASESLILAQLFSKIAGQLSQTNPASDLLDEIERYLEVF
                     RNRSLPKTREEFETRATLLQLLREAKTFIQVKVDFYQKYRQ"
     gene            complement(27288..28503)
                     /gene="sstT"
                     /locus_tag="ACL3EZ_000401"
                     /pseudo
     CDS             complement(27288..28503)
                     /gene="sstT"
                     /locus_tag="ACL3EZ_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000713440.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA];
                     GO_process: GO:0015826 - threonine transport [Evidence
                     IEA];
                     GO_process: GO:0032329 - serine transport [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
     gene            28642..29202
                     /locus_tag="ACL3EZ_000402"
     CDS             28642..29202
                     /locus_tag="ACL3EZ_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel domain-containing
                     protein"
                     /protein_id="HGR0392034.1"
                     /translation="MQKFIQAYIEKLDVTTIIENILTKVISLLLLLIVFYIAKKMLHT
                     MVQRIVKPSLKMSRHDVGRQKTISRLLENVFNYTLYFFLLYCILSILGLPVSSLLAGA
                     GIAGVAIGMGAQGFLSDVINGFFILFERQLDVGDEVVLTNGPITVSGKVVSVGIRTTQ
                     LRSEEQALHFVPNRNITVVSNFSRTD"
     gene            29259..30167
                     /locus_tag="ACL3EZ_000403"
     CDS             29259..30167
                     /locus_tag="ACL3EZ_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HGR0392035.1"
                     /translation="MVLEKQLGNGCTWIDLDLGKLNKLEDLSEIYGLDKETIEYALDR
                     NERAHMDYHRESGTVTFIYNVLDVKKDKAYYETFPMTFIVEHRRLITISNTKNAYVIE
                     QMTRYLESHDTLSIYKFLFASLEIISNAYYPVIEQMDKSRDEVNDLLRQRTTKKNLFV
                     LSDLETGMVYLTAAAKQNRILLEHIQGHALYRSFDEIEREQFDDAMIEAHQLVSMTDL
                     ISQILQQLSASYNNILNNNLNDNLTTLTIISVLLAVLAVVTGFFGMNVPLPLTDEPHA
                     WLYISLASAGLWIVLSLLLRKIAKKS"
     gene            30182..30709
                     /locus_tag="ACL3EZ_000404"
     CDS             30182..30709
                     /locus_tag="ACL3EZ_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008962 - phosphatidylglycerophosphatase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HGR0392036.1"
                     /translation="MAIENYIPDFAVEAVYDLTVPSLQAQGIKAVLVDLDNTLIAWNN
                     PDGTPEMKQWLHDLRDAGIGIIVVSNNTKKRVQRAVEKFGIDYVYWALKPFTFGIDRA
                     MKEFHYDKKEVVMVGDQLMTDIRAAHRAGIRSILVKPLVQHDSIKTQINRTRERRVMR
                     KITEKYGPITYKKGI"
     gene            30712..31818
                     /gene="yqeH"
                     /locus_tag="ACL3EZ_000405"
     CDS             30712..31818
                     /gene="yqeH"
                     /locus_tag="ACL3EZ_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HGR0392037.1"
                     /translation="MEEILCIGCGATIQTTDKAGLGFTPQSALEKGLETGEVYCQRCF
                     RLRHYNEITDVQLTNDDFLKLLHEVGDSDALVVNVIDIFDFNGSVIPGLPRFVSGNDV
                     LLVGNKKDILPKSVKSGKISQWLMKRAYEEGLRPVDVVLTSAQNKHAIKEVIDKIEHY
                     RKGRDVYVVGVTNVGKSTLINAIIQEITGDQNVITTSRFPGTTLDKIEIPLDDGSYIY
                     DTPGIIHRHQMAHYLTAKNLKYVSPKKEIKPKTYQLNPEQTLFLGGLGRFDFIAGEKQ
                     GFTAFFDNELKLHRSKLEGASAFYDKHLGTLLTPPNSKEKEDFPRLVQHVFTIKDKTD
                     LVISGLGWIRVTGTAKVAVWAPEGVAVVTRKAII"
     gene            32032..32343
                     /gene="yhbY"
                     /locus_tag="ACL3EZ_000406"
     CDS             32032..32343
                     /gene="yhbY"
                     /locus_tag="ACL3EZ_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HGR0392038.1"
                     /translation="MSLTSKQRAFLNSQAHTLKPIIQIGKNGLNDQIKTSVRQALDAR
                     ELIKVTLLQNTDENIHEVAEILEEEIGVDTVQKIGRILILFKQSSKKENRKISKKVKE
                     I"
     gene            32395..33024
                     /locus_tag="ACL3EZ_000407"
     CDS             32395..33024
                     /locus_tag="ACL3EZ_000407"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HGR0392039.1"
                     /translation="MTIELLTPFTKVELEPEIKEKKRKQVGILGGNFNPVHNAHLIVA
                     DQVRQQLGLDQVLLVPEYQPPHVDKKETIPEHHRLKMLELAIEGIDGLVIETIELERK
                     GISYTYDTMKILTEQHPDTDYYFIIGADMVDYLPKWYRIDELVDMVQFVGVQRPRYKA
                     GTSYPVIWVDVPLMDISSSMVRDFIAQGRKPNFLLPQPVLDYIEKEGLY"
     gene            33024..33617
                     /gene="yqeK"
                     /locus_tag="ACL3EZ_000408"
     CDS             33024..33617
                     /gene="yqeK"
                     /locus_tag="ACL3EZ_000408"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HGR0392040.1"
                     /translation="MSYQDYINCSREALLEKMAELLPEKRLTHCLGVERAAMELAQRF
                     GVDVEKASLAGLLHDYAKKLSDQEFLDLIDRYQLDPGLKNWGNNVWHGMVGIYKIQED
                     LDLHDSEILRAIEVHTVGAGQMTDLDKVVYVADYIEHNRSFPGVDVAREVASLSLNKA
                     VAYETARTVEYLAHQGFPIYPQTLETYNAFVHYLKEN"
     gene            33618..34118
                     /locus_tag="ACL3EZ_000409"
     CDS             33618..34118
                     /locus_tag="ACL3EZ_000409"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase family protein"
                     /protein_id="HGR0392041.1"
                     /translation="MKMAFIIIDVQNVLVETGFQTKSLLEKISYLQNQARSKNIEIIY
                     VQHIENSEAQTSEDWQLSALLNRKPAEKVFQKKYNSIFKETGLKEYLDKQGIEKLVLC
                     GMQTEYCVDTSVKIAFEYGYQLIVPEGAVTTFDGDDIPAETINEFYEDIWEERFADVL
                     DYKHIF"
     gene            34131..34484
                     /gene="rsfS"
                     /locus_tag="ACL3EZ_000410"
     CDS             34131..34484
                     /gene="rsfS"
                     /locus_tag="ACL3EZ_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0017148 - negative regulation of
                     translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HGR0392042.1"
                     /translation="MNEKELLELVVKAADEKRAEDILALDVQDLTSVTDYFVITSSMN
                     SRQLDAIAANIREKVAQAGFKGSHVEGDAAGGWVLLDLGAVVVHIFSEEMRAHYNLEK
                     LWHEANSVDISEALA"
     gene            34593..35333
                     /locus_tag="ACL3EZ_000411"
     CDS             34593..35333
                     /locus_tag="ACL3EZ_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGR0392043.1"
                     /translation="MATYETFAAVYDAVMDDSLYDKWTNFSLRHLPKTKERKKLLELA
                     CGTGIQSVRFSQAGFDVTGLDLSADMLKIAEKRATSAKQKIAFIEGNMLNLSKAGKYD
                     FVTCYSDSICYMQDEVEVGDVFKDVYNALNEEGVFIFDVHSTYQTDEVFPGYSYHENA
                     EDFAMLWDTYEDEVPHSIVHELTFFIKEADGSFSRHDEVHEERTYEILTYDILLEQAG
                     FKSFKLYADFEDKEPTETSTRWFFVAQK"
     gene            35343..36440
                     /locus_tag="ACL3EZ_000412"
     CDS             35343..36440
                     /locus_tag="ACL3EZ_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000156376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HGR0392044.1"
                     /translation="MTITGIIAEFNPFHNGHKYLLDQAEGLKIVAMSGNFMQRGEPAI
                     VDKWTRAQMALENGADLVVELPFLVSVQAADFFGQGAVDILDRLGIDSLVFGTEEVRD
                     YQKIADLYTEKGAEMEKFVENLPDSLSYPQKTQAMWKEFAGLDFSGNTPNHVLALAYA
                     KAVAGRNIKLHPIQRQGAGYHSVNKDVDFASATALRQHQKDQDFLERFMPSVALFEQA
                     SKVIWEDYFPLLRYQILSNPDLTTIYQVNQEMAVRIKEAIKTAQSVEELVELVTTKRY
                     TKARVRRLLTYILVQARESDLPEGIHVLGFTEKGRQHLKYLKGQVSLVSRIGKEPWDV
                     MTQKADQIYQLGNPSIAEQNFGRVPIRIETN"
     gene            36788..39535
                     /locus_tag="ACL3EZ_000413"
     CDS             36788..39535
                     /locus_tag="ACL3EZ_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIR2 family protein"
                     /protein_id="HGR0392045.1"
                     /translation="MEENYNLSITQIKNSIKENSLVLFVGAGISANSNLPTWGELIQS
                     LKKELNIPEERTDSPLRIAQYYYDTFGKNQYTKKIEEIFFKKGLSKPNELHKLIEKIA
                     PKHIITTNYDSLLESQFESGLLKYNVVAEDKDIPYTSSERYLIKMHGDFSKKNIVLKE
                     DDYLDYHLNFPMISTLIQSLIMNHTLLFVGYSLSDSTFNSIFRMIQNTFKLDAKNAYF
                     YTPEEPSMIIREYYKKQGIFIISNEENLGQETSEKQNKLYCRTKDFLEVLSENRSQDV
                     NNADDLWNQLAFLDRLSFIDAKDFSRYSDLKKRALNWDDEYCWFGNDQLRFEIDGHEE
                     LRIMVSKKSLLNRFLDMEIGEPRDLKGNRFLSKAFKLYEEKQYSLAKAKFRELANIAF
                     RQKDYFNFLVCEFNFQQIQIIDRYEKTPSYAEPLYDGELSELTEQILNSVTGDEKKII
                     EFFRDSILNFNFLYRKLETINELFDEIREEHESYRRGGWSANNHLFNAEFTVKNLYNF
                     LKLNCLCVEHYKIYKSIINRYLEILLLSYDNSYVNPDSSIFDRTSSWLKNLDLDDVQL
                     ILPNIDFKVVNLYFRNYSFGKIKVTEEAKDYLLNRITYLQERLEITEDENLRELKNML
                     IFLPLVDDIDIEKVIEILNNQTLYYNWREEFRRIIKIVLDNMDVIDKDSLKSKIIGIV
                     NKHLNEILEKNFSLYNSVYPLYSQLLEYCSTDQETAIIVLEKFNTDILRIKYKNDDIK
                     NIIEYSDLICHLFKYFEKDIKDDILDTLKVYEESENIIYHKVIDLMSYNVYDFPQIQN
                     KIYHYLIKRINDKRVEGVKTFPDPREKSVSDLYNLSRKGYFSDFEILKDIEEDIRGLY
                     PEVDWTWFHDRSDDVIHRLLEHRTPNNIKTYFSKNEEDNKLINEYILKAFDEDKLILK
                     K"
     gene            39879..41492
                     /locus_tag="ACL3EZ_000414"
     CDS             39879..41492
                     /locus_tag="ACL3EZ_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HGR0392046.1"
                     /translation="MEIMSLAIAVFAVIIGLVIGYVSISAKMKSSQEAAELMLLNAEQ
                     EATNLRGQAEREADLLVNEAKRESKSLKKEALLEAKEEARKYREEVDAEFKSERQELK
                     QIESRLTERATSLDRKDDNLTSKEQTLEQKEQSISDRAKNLDAREEQLEEVERQKEAE
                     LERIGALSQAEARDIILAQTEENLTREIASRIREAEQEVKERSDKMAKDILVQAMQRI
                     AGEYVAESTNSTVHLPDDTMKGRIIGREGRNIRTFESLTGVDVIIDDTPEVVTLSGFD
                     PIRREIARMTMEMLLKDGRIHPARIEELVEKNRQEIDNKIREYGEAAAYEIGAPNLHP
                     DLMKIMGRLQFRTSYGQNVLRHSIEVAKLAGIMASELGENAALARRAGFLHDIGKAID
                     HEVEGSHVEIGMELARKYKEPPVVVNTIASHHGDVEAESVIAVIVAAADALSAARPGA
                     RSESLESYIKRLHDLEEIANGFEGVQTSFALQAGREIRIMVNPGKIKDDKVTILAHKV
                     RKKIENNLDYPGNIKVTVIRELRAVDYAK"
     gene            41622..42248
                     /gene="gmk"
                     /locus_tag="ACL3EZ_000415"
     CDS             41622..42248
                     /gene="gmk"
                     /locus_tag="ACL3EZ_000415"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004385 - guanylate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006163 - purine nucleotide metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HGR0392047.1"
                     /translation="MADRGLLIVFSGPSGVGKGTVRREIFESSENQFQYSVSMTTRAQ
                     RPGEVDGVDYFFRTREEFEELIRQGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLE
                     IEVQGALQVKKKVPDAVFIFLTPPDLDELQDRLVGRGTDSAEVIAQRIEKAKEEIALM
                     REYDYAIVNDQVPLAAERVKCVIEAEHFCVDRVIGHYQEMLPKSPTTR"
     gene            42273..42587
                     /gene="rpoZ"
                     /locus_tag="ACL3EZ_000416"
     CDS             42273..42587
                     /gene="rpoZ"
                     /locus_tag="ACL3EZ_000416"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HGR0392048.1"
                     /translation="MMLKPSIDTLLDKVPSKYSLVILEAKRAHELEAGAPATQGFKSE
                     KSTLRALEEIESGNVTIHPDPEGKREAVRRRIEEEKRRKEEEEKKIKEQIAKEKEDGE
                     KI"
     gene            42653..45049
                     /locus_tag="ACL3EZ_000417"
     CDS             42653..45049
                     /locus_tag="ACL3EZ_000417"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001162119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0032508 - DNA duplex unwinding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HGR0392049.1"
                     /translation="MALAKIIVDVPLMQTDQPYSYRIPEEFEGMLEVGMRVHVPFGKG
                     NRLIQGIVLGLKSQSDGEEMEQDLKDIAEVLDFSPVLTPEQLWLAEELRKSVFSYKIS
                     ILKAMLPGFLNSSYDKILYPLEGLSQEERVRLFGSEDSLAFSSLDLAKQAEMMRLTRK
                     GLLGLEYQAVDQKKVKTQSWYEVDHAQLEGVEISTRAKKKLELRDYLLSHPESASLAS
                     LLESYSREQVNFFVDQGAVTIVQKEVQRSAAYFGGIEASRPLELNPEQRQARDAVVSS
                     IGSSQPPFLLQGITGSGKTEVYLQIIQGALDKGKTAILLVPEISLTPQMTERFIARFG
                     DKVAILHSGLSNGEKYDEWRKVERGDAQVVVGARSAIFAPLKNLGVMIIDEEHEAAYK
                     QDSNPRYHAREVAILRAQYNQATLVLGSATPSLESRARAGKGVYQHLRLTQRANPLAT
                     IPEVQVIDFRDYIGQNETSNFTPPLLEAIQDRLVKKEQVVLMLNRRGYSSFVMCRECG
                     TVDTCPNCDISLTLHMDTKTMNCHYCGFSKDIPQVCPNCKSRSIRYYGTGTQKAYDEL
                     AELFPQARILRMDVDTTRKKGSHQALLDQFGRGEADILLGTQMIAKGLDFPNVTLVGV
                     LNADTALNLPDFRSSERTFQLLTQVAGRAGRAEKAGQVLIQSYNPQHYAIRFAKDQDY
                     EGFYAYEMGIRRQLGYPPYYFTIGITLSHKKEEEVFKRAYEVMNILRSGLSETSPILG
                     PTPKPIARTHNLYHYQILIKYRLEDELGPTLNQVLALTQERENSELRLSIDHEPQQFL
                     "
     gene            45062..45997
                     /gene="fmt"
                     /locus_tag="ACL3EZ_000418"
     CDS             45062..45997
                     /gene="fmt"
                     /locus_tag="ACL3EZ_000418"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004479 - methionyl-tRNA formyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0071951 - conversion of methionyl-tRNA to
                     N-formyl-methionyl-tRNA [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HGR0392050.1"
                     /translation="MTKLIFMGTPDFSATVLKGLLTDDRYEILAVVTQPDRAVGRKKV
                     IQETPVKQAAKEAGLSIYQPEKLSGSPEMEDLMKLGADGIVTAAFGQFLPSKLLDSMD
                     FAVNVHASLLPRHRGGAPIHYALIQGDEEAGVTIMEMVKEMDAGDMISRRSIPITDED
                     NVGTLFEKLALVGRDLLLDTLPAYIAGDIKPEPQDTSQVTFSPNIKPEEEKLDWNKTN
                     RQLFNQIRGMNPWPVAHTFLKGDRFKIYEALPVEGQGNPGEILSIGKKELIVATAEGA
                     LSLKQVQPAGKPKMDIASFLNGVGRTLTVGERFGD"
     gene            45990..47303
                     /gene="rsmB"
                     /locus_tag="ACL3EZ_000419"
     CDS             45990..47303
                     /gene="rsmB"
                     /locus_tag="ACL3EZ_000419"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0001510 - RNA methylation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HGR0392051.1"
                     /translation="MTKVETARSLALAVLEDVFVNQAYSNIALNKHLKGSQLLAADKG
                     LVTELVYGTVARKLTLEWYLSHFIEDRDQLDSWLYVLLLMSAYQLRYLDKIPDHAVVN
                     EAVELAKLRKKGSEKLVNAVLRRILREGWPDIASIKRKNKRDSIAYSLPVWLVAKLKE
                     EYGEERAKAIFESLLVRNKASIRVTDLSRKEEIQALLEANNSLLATTGLVKEQGHFAG
                     HNLFADGAITIQDESSQLVAPTLDLQGDERVLDACAAPGGKTAHIASYLTTGQVTALD
                     LYDHKLDLIQENAQRLGVADRVQTQKLDARKVHEFFDQDSFDKILVDAPCSGIGLLRR
                     KPDIKYNKETADFASLQEIQLEILGSVCQILGKGGIITYSTCTIVSEENFQVVKAFLE
                     SHPEFEQVKLEHECKDIMKDGCILITPELYGSDGFFISQFRKISD"
     gene            47318..48058
                     /locus_tag="ACL3EZ_000420"
     CDS             47318..48058
                     /locus_tag="ACL3EZ_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004722 - protein serine/threonine
                     phosphatase activity [Evidence IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HGR0392052.1"
                     /translation="MEISLLTDVGQKRTNNQDYVNHYVNRAGRTMIILADGMGGHRAG
                     NIASEMAVTDLGVAWVDTQIDTVNEVREWFAHYLEIENQKIHQLGQDEAYRGMGTTLE
                     VLAIVDNQAIYAHIGDSRIGLIRGEEYHQLTSDHSLVNELLKAGQLTPEEAEAHPQKN
                     IITQSIGQKDEIQPDFGTVILESGDYLLLNSDGLTNMISGSEIRDIVTSDIPLADKTE
                     TLVRFANNAGGLDNITVALVSMNEEDAE"
     gene            48055..50034
                     /gene="stkP"
                     /locus_tag="ACL3EZ_000421"
     CDS             48055..50034
                     /gene="stkP"
                     /locus_tag="ACL3EZ_000421"
                     /EC_number="2.7.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000614538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine-protein kinase StkP"
                     /protein_id="HGR0392053.1"
                     /translation="MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVL
                     RTNYQTDPIAVARFQREARAMADLDHPHIVRITDIGEEDGQQYLAMEYVAGLDLKRYI
                     KEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
                     FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAV
                     TIALQHFQKPLPSVIAENPSVPQALENVIIKATAKKLTNRYRSVSEMYVDLSSSLSYN
                     RRNESKLIFDETSKADTKTLPKVSQSTLTSIPKAQAQTEHKSIKNPSQAVTEETYQPQ
                     APKKHRFKMRYLILLGSLVLVAASLIWILSRTPATIAIPDVAGQTVAEAKATLKKANF
                     EIGEEKTEASEKVEEGRIIRTDPGAGTGRKEGTKINLVVSSGKQSFQISNYVGRKSSD
                     VIAELKEKKVPDNLIKIEEEESNESEAGTVLKQSLPEGTTYDLSKATQIVLTVAKKAT
                     TIQLGNYIGRNSTEVISELKQKKVPENLIKIEEEESSESEPGTIMKQSPGAGTTYDVS
                     KPTQIVLTVAKKVTSVAMPSYIGSSLEFTKNNLIQIVGIKEANIEVVEVTTAPAGSVE
                     GMVVEQSPRAGEKVDLNKTRVKISIYKPKTTSATP"
     gene            50149..50907
                     /locus_tag="ACL3EZ_000422"
     CDS             50149..50907
                     /locus_tag="ACL3EZ_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HGR0392054.1"
                     /translation="MEESKELNAVIDVIMLAGTILLKSGSEIHRVEDTMIRIAHSQGI
                     VDCNVLAMPAAIFFSIENTNISRMKRVTSSSYNIEKVCDVNQISRQLVGGQIDLETAF
                     KQLTALQAQPLPYTKLQVTLAATFSAPFFSVMFSGNIYDALGAGVATLFGFAFSLYVE
                     KFIRIPFVTAFAGAFVFGIIAQFWARYTGFPSTADLIIAGAVMPFVPGIALTNAVRDI
                     MTNHINSGMSKMFESLLITLALGAGTSVALVLMN"
     gene            50909..51358
                     /locus_tag="ACL3EZ_000423"
     CDS             50909..51358
                     /locus_tag="ACL3EZ_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HGR0392055.1"
                     /translation="MTLTTFLLQAVASFLAIITFLIVLNVQRSMLLPGGILGMTVWLI
                     YLLLKEPTNVIVATFIAAIIGSCVSQILSILYKTPAVVFILAILAPLVPGYLSYRTTA
                     FFVTGDYNKALASATLVVMLALVISIGMASGTVILRLYHYIKTHRVS"
     gene            51420..52046
                     /locus_tag="ACL3EZ_000424"
                     /pseudo
     CDS             51420..52046
                     /locus_tag="ACL3EZ_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            52114..52362
                     /locus_tag="ACL3EZ_000425"
     CDS             52114..52362
                     /locus_tag="ACL3EZ_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0392056.1"
                     /translation="MVSSSGSEFQSGWQEHQLIAEKVSKTLDKTFDKDVREIPTSQFY
                     QKFVDEMGRTYSGNLILQELITVNGAYKATYIDELSSN"
     gene            52493..53665
                     /locus_tag="ACL3EZ_000426"
     CDS             52493..53665
                     /locus_tag="ACL3EZ_000426"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004181031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004421 - hydroxymethylglutaryl-CoA
                     synthase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HGR0392057.1"
                     /translation="MTIGIDKIGFATSQYVLKLQDLAEARGIDPEKLSKGLLLKELSI
                     APLTEDIVTLAASASDSILTEQERQEVDMVIVATESGIDQSKAAAVFVHGLLGIQPFA
                     RSFEIKEACYGATAALHYAKLHVENSPESKVLVIASDIAKYGIETPGEPTQGAGSVAM
                     LITQNPRMMAFNNDNVAQTRDIMDFWRPNYSTTPYVNGVYSTQQYLDSLKTTWLEYQK
                     RYQLTLDDFAAVCFHLPYPKLALKGLKKIMDKSLPQEKKDLLQKHFDQSILYSQKVGN
                     IYTGSLFLGLLSLLENTDSLKAGDKIALYSYGSGAVAEFFSGELVEGYEAYLDKDRLN
                     KLNQRTALSVADYEKVFFEEVNLDETKSAQFAGYENQDFALVEILDHQRRYSKVEK"
     gene            53665..54939
                     /locus_tag="ACL3EZ_000427"
     CDS             53665..54939
                     /locus_tag="ACL3EZ_000427"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004420 - hydroxymethylglutaryl-CoA
                     reductase (NADPH) activity [Evidence IEA];
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_process: GO:0015936 - coenzyme A metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HGR0392058.1"
                     /translation="MKISWNGFSKKSYQERLELLKAQALLSPERQASLEKDEQMSVTV
                     ADQLSENVVGTFSLPYSLVPEVLVNGQEYTVPYVTEEPSVVAAASYASKIIKRAGGFT
                     AQVHQRQMIGQVALYQVANPKLAQEKIASKKAELLELANQAYPSIVKRGGGARDLHVE
                     QIKGEPDFLVVYIHVDTQEAMGANMLNTMLEALKPVLEELSQGQSLMGILSNYATDSL
                     VTASCRIAFRYLSRQKDQGREIAEKIALASQFAQADPYRAATHNKGIFNGIDAILIAT
                     GNDWRAIEAGAHAFASRDGRYQGLSCWTLDLEREELVGEMTLPMPVATKGGSIGLNPR
                     VALSHDLLGNPSARELAQIIVSIGLAQNFAALKALVSTGIQQGHMKLQAKSLALLAGA
                     SESEVAPLVERLISDKTFNLETAQRYLENLRS"
     gene            complement(54974..55939)
                     /locus_tag="ACL3EZ_000428"
     CDS             complement(54974..55939)
                     /locus_tag="ACL3EZ_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGR0392059.1"
                     /translation="MVAKLTDVAKLAGVSPTTVSRVINKKGYLSEKTIQKVNEAMREL
                     GYKPNNLARSLQGKSAKLIGLIFPNISNVFYAELIDKLEHQLFKNGYKTIICNSEHDS
                     EKEREYIEMLEANQVDGIISGSHNLGIEDYNRVTAPIISFDRNLSPDIPVVSSDNYAG
                     GVLAAQTLVKTGAQSIIMITGNDNSNSPTGLRHAGFASVLPKAPIINVSSDFSPVRKE
                     MEIKNILTREKPDAIFASDDLTAILVIKIAQELGISVPKELKVIGYDGTYFIENYYPQ
                     LATIKQPLEEIACLTIDLLLQKIEGKEVATTGYFLPVTLLPGKSI"
     gene            complement(55920..57374)
                     /locus_tag="ACL3EZ_000429"
     CDS             complement(55920..57374)
                     /locus_tag="ACL3EZ_000429"
                     /EC_number="3.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004564 - beta-fructofuranosidase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="HGR0392060.1"
                     /translation="MEWTTERRYRLYQDWTQEEIQHIKENMAQSPWHTHYHVEPKTGL
                     LNDPNGFSYFDGKWILFYQNFPFGAAHGLKSWAQLESDDLVHFKETGIKVLPDTPLDS
                     HGAYSGSAMQFGDNLFLFYTGNVRDENWIRHPYQIGALMDKEGKITKIDKILIDQPAD
                     STDHFRDPQIFNFKGQYYAVVGGQDLEKKGFVRLYKAVNNDYTNWQAVGDLDFANDRT
                     AYMMECPNLVFVEEHPVLLYCPQGLDKKVLDYDNIFPNMYKIGASFDPKNAKMVDVSQ
                     LQNMDYGFEAYATQAFNAPDGRALAVSWLGLPDVSYPSDRFDHQGTFSLVKELTIKDD
                     KLYQYPVAAIKDLRASEEAFSNRSQTKNTYELELNLEANSQSEIVLLADKEGKGLSIN
                     FDLVNGQVTVDRSQAGEQYAQEFGTTRSCPIENQATTATIFIDNSVFEIFINKGEKVF
                     SGRVFPHADQNGILIKSGNPTGTYYELDYGRKTN"
     gene            57750..59687
                     /locus_tag="ACL3EZ_000430"
     CDS             57750..59687
                     /locus_tag="ACL3EZ_000430"
                     /EC_number="2.7.1.211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-specific PTS transporter subunit IIBC"
                     /protein_id="HGR0392061.1"
                     /translation="MDYSKVAAEVIGAVGKDNLVAAAHCATRLRLVLKDEAKVNQAAL
                     DNNADVKGTFSTNGQYQIIIGPGDVNFVYAEIIKKTGLKEVSTDDLKEIANKDKKFNP
                     LMDLIKLLSDIFVPIIPALVAGGLLMALRNFLTSPDLFGPQSIEDMYPAIKGFSAMIQ
                     LMSAAPFMFLPVLVGISAAKRFGANQFLGAAIGMIMTTPDLGGKEAFWDILGFHVTQT
                     NYAYQVIPVLVAVWLLANLEKFFHKKLPSAVDFTFTPLLSVMITGFLTFTVIGPVMLV
                     VSDAITNAIVWLYNTTGAFGMGLFGGTYSLIVMTGLHQSFPAIETQLLSAYNNNGTGF
                     GDYIFVVASMANVAQGAATLAVYFLTKNAKTKGLSSSAAVSAFLGITEPALFGVNLKY
                     KFPFFCALAGSAIGAFVAGLTHVIAVSLGAAGFIGFLSIKAGSIPMYIIAEIMSFVAA
                     FAFTYFYGKTKAASVFADEAATATAETVTEPTVEAPVVEETDTLQNETLVTPIVGDVV
                     ALADVNDPVFSSGAMGQGIAVKPSQGVVYAPADAEVSIAFPTGHAFGLKTRNGAEVLI
                     HVGIDTVSMNGDGFEAKVAQGDKVKVGDVLGTFDSNKIAAAGLDDTTMVIVTNTADYA
                     SVAPVATGSVAKGDAVIEVKI"
     gene            59836..60723
                     /gene="scrK"
                     /locus_tag="ACL3EZ_000431"
     CDS             59836..60723
                     /gene="scrK"
                     /locus_tag="ACL3EZ_000431"
                     /EC_number="2.7.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000164317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008865 - fructokinase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructokinase ScrK"
                     /protein_id="HGR0392062.1"
                     /translation="MTKLYGSLEAGGTKFVCAVGDENFNVVEKTQFPTTTPIETIDKT
                     IEFFSKFDNLAGLAVGSFGPIDIDKNSKTYGFITTTPKPNWANVDLLGALRRALNVPM
                     YFTTDVNSSAYGEMVARNNAGGRIENLVYYTIGTGIGAGVIQRGEFIGGVGHPEMGHY
                     YVARHPMDIEKEFKGVCPFHKGCLEGYAAGPSLEARTGVRGETIELNNPVWDVQAYYI
                     AQAAVNATVTFRPDVIVFGGGVMAQQHMLDRVREKFTSLLNGYLPVPDVRDYIVTPAV
                     AGNGSATLGNFVLAKEVSK"
     gene            complement(61043..61660)
                     /locus_tag="ACL3EZ_000432"
     CDS             complement(61043..61660)
                     /locus_tag="ACL3EZ_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HGR0392063.1"
                     /translation="MSQDKQMKAVSPLLQRVINISSIVGGVGSLIFCIWAYQAGILQS
                     KETLSAFIQQAGIWGPPLFIFLQILQTVVPIIPGALTSVAGVFIYGHIIGTIYNYIGI
                     VIGCAIIFYLVRLYGAAFVQSVVSKRTYDKYIGWLDKGNRFDRFFIFMMIWPISPADF
                     LCMLAALTKMSFKRYMTIIILTKPFTLVVYTYGLTYIIDFFWQML"
     gene            complement(62075..62288)
                     /locus_tag="ACL3EZ_000433"
                     /pseudo
     CDS             complement(62075..62288)
                     /locus_tag="ACL3EZ_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(62656..62847)
                     /locus_tag="ACL3EZ_000434"
     CDS             complement(62656..62847)
                     /locus_tag="ACL3EZ_000434"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0392064.1"
                     /translation="MKSKERTRKLAVGCSKYSFEVADKTDEVSSKHCFEVVDRTDEVS
                     NYIYGKAKLTWFEEIFEEY"
     gene            62969..63862
                     /locus_tag="ACL3EZ_000435"
     CDS             62969..63862
                     /locus_tag="ACL3EZ_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0392065.1"
                     /translation="MLEVRSLEKSFGSKQVLFGIDFQARPGRILGLVGKNGAGKTTIF
                     HSILKFLEYQGEIGLDGQDIRQETYARIGYLPEERSLMPKLTVLEQVRYLATLKGMDA
                     KEVKEKLPQWMKRLEVKGKLTDKIKSLSKGNQQKIQLIITLIHEPDLIILDEPFSGLD
                     PVNTELLKQVIFQEKERGATIIFSDHVMTNVEELCDDILMIRDGRVVLHGPVQDVRNQ
                     YGKTRLFVSSERSKEELENLPHVKQVSLTKQGSWKLILEDESAGRELFPILTQGQYIA
                     TFDQQAPTIDEIFKLESGVEV"
     gene            63859..65058
                     /locus_tag="ACL3EZ_000436"
     CDS             63859..65058
                     /locus_tag="ACL3EZ_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0392066.1"
                     /translation="MRNMWVVIKETYLRHVESWSFFFMVISPFLFLGISVGIGHIQGS
                     SMAKNNKVAVVTTVPSVAEGLKNVNGVNFDYKDEASAKEAIKEEKLKGYLTIDQEDSV
                     LKAVYHGETSLENGIKFEVTGTLNELQNQLNRSTASLSQEQEKRLAQTIQFTEKIDEA
                     KENKKFIQTIAAGALGFFLYMILITYAGVTAQEVASEKGTKIMEVVFSSIRASHYFYA
                     RMMALFLVILTHIGIYVVGGLAAVLLFKDLPFLAQSGILDHLGDAISLNTLLFILISL
                     FMYVVLAAFLGSMVSRPEDSGKALSPLMILIMGGFFGVTALGAAGDNLLLKIGSYIPF
                     ISTFFMPFRTINGYAGGAEAWISLAITVIFAVVATGFIGRMYASLVLQTDDLGIWKTF
                     KRALSYK"
     gene            complement(65411..66178)
                     /locus_tag="ACL3EZ_000437"
     CDS             complement(65411..66178)
                     /locus_tag="ACL3EZ_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000498762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0392067.1"
                     /translation="MFWNLVHYEFKNVNKWYLALYAAVLVLSALIGIQTQGFKNLPYQ
                     ESQATMLLFLATVFGGLMLTLAISTIFLIIKRFKGSVYDRQGYLTLTLPVSEHHIITA
                     KLIGAFIWSLISTAVLALSAVIILALTAPEWIPLSYVITFVETHLPQIFLTGISFLLN
                     TISGILCIYLAISIGQLFNEYRTALAVAAYIGIQIVIGFIELFFNLSSNFYVNSLVGL
                     NDHFYMGAGIAIVKELIFIAIFYLGTYYILRNKVNLL"
     gene            complement(66195..66890)
                     /locus_tag="ACL3EZ_000438"
     CDS             complement(66195..66890)
                     /locus_tag="ACL3EZ_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0392068.1"
                     /translation="MSLLAFENVSKSYGATPALENVSLDIPAGKIVGLLGPNGSGKTT
                     LIKLINGLLQPDQGRVLINDMDPSPATKAVVAYLPDTTYLNEQMKVKEALTYFKTFYK
                     DFNLERAHHLLADLGIDENSRLKKLSKGNKEKVQLILVMSRDARLYVLDEPIGGVDPA
                     ARAYILNTIINNYSPTSTVLISTHLISDIEPILDEIVFLKDGKVVRQGNVDDIRYESG
                     ESIDQLFRQEFKA"
     gene            complement(66895..67260)
                     /locus_tag="ACL3EZ_000439"
     CDS             complement(66895..67260)
                     /locus_tag="ACL3EZ_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HGR0392069.1"
                     /translation="MSWTFDNKKPIYLQIMEKIKLQIVSHTLEPNQQLPTVRELASEA
                     GVNPNTIQRALSDLEREGFVYSKRTTGRFVTKDKELIAQSRKQLSEEELEHFVSSMTH
                     FGYEKEELPGVVSDYIKGV"
     gene            67400..67873
                     /gene="nrdR"
                     /locus_tag="ACL3EZ_000440"
     CDS             67400..67873
                     /gene="nrdR"
                     /locus_tag="ACL3EZ_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001203675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0140110 - transcription regulator activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator NrdR"
                     /protein_id="HGR0392070.1"
                     /translation="MRCPKCGATKSSVIDSRQAEEGNTIRRRRECDECQHRFTTYERV
                     EERTLVVVKKDGTREQFSRDKIFNGIIRSAQKRPVSSDEINMVVNRIEQKLRGRNENE
                     IQSEDIGSLVMEELAELDEITYVRFASVYRSFKDVSELESLLQQITQSSKKKKER"
     gene            67874..69043
                     /locus_tag="ACL3EZ_000441"
     CDS             67874..69043
                     /locus_tag="ACL3EZ_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HGR0392071.1"
                     /translation="MKPIDRFSYLKNNRVSQDTSSLVQCYLPIIGQEALSLYLYTISF
                     WDNGRKEYLFSSILNHLNFGMDRLIKSLKILSAFNLLTLYQKGDVYQLALHAPLSSQD
                     FLEYPVYRRLLEKKIGDSAVEDLKVESADGEEIPVSLNQVFPELAELGSQEDLGLKKK
                     VANDFDLEHFRQLMARDGLRFADEQSDVLNLFAIAEEKKWTWFETYQLAKSTAVSQVI
                     STKRMREKIAQKPVSSDFSLKETTIIKEAKSKTALQFLAEIKQTRKGTITQTERELLQ
                     QMAGLGLLDEVINIILLLTFNKVDSANINEKYAMKVANDYAYQKIHSAEKAVLRIRER
                     GQKAKTQKQNQTAPVKTNVPKWSNPEYKNETSEETRLELERKKQELLARLEKGGD"
     gene            69044..69940
                     /gene="dnaI"
                     /locus_tag="ACL3EZ_000442"
     CDS             69044..69940
                     /gene="dnaI"
                     /locus_tag="ACL3EZ_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HGR0392072.1"
                     /translation="MESVGDVLKRQPSRFYYQDLVQKIMKDPDVAAFIQQESLTPEEL
                     NRSISKFNQYITERDKFLRGDTDYIAKGYKPILVKNHGYADVSYEETPELIAAEKEAA
                     IKNRLKLINLPASLKKASLAQVDLDDLGRLPVFEKLLAFVEQYPAIRKGLYLYGDFGV
                     GKSFMVAALAHDLSEKRGVSSTLLHYPSFVIDVKNAISDGNVKTLVDEIKLSEVLILD
                     DIGAEQSTVWVRDEILQVILQYRMQENLPTFFTSNFNFEDLEKHFAKVKHGNDETWEA
                     RRVMERIRYLAEETRLEGVNRR"
     gene            69937..70650
                     /locus_tag="ACL3EZ_000443"
     CDS             69937..70650
                     /locus_tag="ACL3EZ_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent oxidoreductase"
                     /protein_id="HGR0392073.1"
                     /translation="MTETIKLMKAHTSVRRFKEQEIPQVDLNEILTAAQMASSWKNFQ
                     SYSVIVVRSQEKKDALYELVPQEAIRQSAVFLLFVGDLNRAEKGARLHTDTFQPQGVE
                     GLLISSVDAALAGQNALLAAESLGYGGVIIGLVRYKSEEVAELFNLPDYTYSVFGMAL
                     GVPNQHHDMKPRLPLENVVFEEEYQEQSTEAIQAYDRVQADYAGARATTSWSQRLAEQ
                     FGQAEPSSTRKNLEQKKLL"
     gene            70664..71974
                     /gene="der"
                     /locus_tag="ACL3EZ_000444"
     CDS             70664..71974
                     /gene="der"
                     /locus_tag="ACL3EZ_000444"
                     /EC_number="3.6.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HGR0392074.1"
                     /translation="MALPTIAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYA
                     TGEWLNRSFSMIDTGGIDDVDAPFMEQIKHQAEIAMEEADVIVFVVSGKEGITDADEY
                     VARKLYKTHKPVILAVNKVDNPEMRNDIYDFYALGLGEPLPISSVHGIGTGDVLDAIV
                     ENLPNEYEEENPDVIKFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFT
                     DTDGQEFTMIDTAGMRKSGKVYENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDK
                     RIAGFAHEAGKGMIIVVNKWDTLEKDNHTMKNWEEDIREQFQYLPYAPIIFVSALTKQ
                     RLHKLPEMIKQISESQNTRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVATKP
                     PTFVIFVNEEELMHFSYLRFLENQIRKAFVFEGTPIHLIARKRK"
     gene            72065..72400
                     /locus_tag="ACL3EZ_000445"
     CDS             72065..72400
                     /locus_tag="ACL3EZ_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0392075.1"
                     /translation="MEHLFKFLLLAPYFYFDNWIEKANRNSKFFPIFYYFYWFYIPFY
                     SLFSLAWTVVSVLFFNTVLRNVTDIKLWGIWFLFILLAIGMNWLTYSCFKEMFRLRQE
                     LGKSKGGRH"
     gene            72540..72890
                     /locus_tag="ACL3EZ_000446"
     CDS             72540..72890
                     /locus_tag="ACL3EZ_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0392076.1"
                     /translation="MEHLFKMVILLPCFYFFSWIERANRDSKIFSIFYYFYWIYITLY
                     ALFSLAWTVFSVLLFNIVLRNVADIKSWGVWLLLLLIAFASDWLDYICFKKMLDLRRE
                     LGKSKGVHKGRCRN"
     gene            complement(73112..73963)
                     /locus_tag="ACL3EZ_000447"
                     /note="rgg1518"
     CDS             complement(73112..73963)
                     /locus_tag="ACL3EZ_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rgg/GadR/MutR family transcriptional regulator
                     Rgg1518"
                     /protein_id="HGR0392077.1"
                     /translation="MRWDYGQIFKEIRKSKGLTQQDVCGQVIHRTTLTNIEHGKVIPS
                     FENMVFLLEQIDMSLAEFKYICNEYHPSKRRDIIVESQNPSTFQDTRKMVELTEKCQK
                     YLKTHHDVPIQNIYRHTKIVTELRTKGFKNNHVLKDLYEEIWDYLEPMDTWYISDLKL
                     LGTILFFFPSENLPLLIDRIMKTIEKYKYFRETKAFLSSFLANLSTVYFQHHLFKECE
                     TITLQLLVLAEELKIYDILGFSQVRLGILQHNSDLIDKGITLLRLTKEEALVKILEKE
                     INDFSNL"
     gene            74290..74682
                     /locus_tag="ACL3EZ_000448"
     CDS             74290..74682
                     /locus_tag="ACL3EZ_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0392078.1"
                     /translation="MKIKKLLKMVIPVLMISAVGTTFVEANQIGAFSNFVITTSYKRT
                     GYLTKENEGAEYIMNLNPCRNLHPMTVKHRIVNSNGEARSGESLTTCGTRSTHGNWAT
                     VGYVYAVDMARQNWWDLSAAISGSWSPN"
     gene            74704..75495
                     /locus_tag="ACL3EZ_000449"
     CDS             74704..75495
                     /locus_tag="ACL3EZ_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0392079.1"
                     /translation="MKIPLLTFARHKFVYVLLTLLFLALVYRDVLMTYFFFDIHAPDL
                     AKFDGQAIKNDLLKSALDFRILQFNLGFYQSFIIPIIIVLLGFQYIELKNKVLRLSIG
                     REVSYQGLKRKLTLQVASIPCLIYLVTVLIIAIITYFFGTFSPLEWNSLFSDGSGLQR
                     LLDGEIKSYLFFTCVLLIGIFINAIYFLQIVDYVGNVTRSAITYLMFLWLGSMLLYSA
                     LPYYMVPMTSLMQASYGDVSLMKLFTPYILYVVPYMVLKKYEDNV"
     gene            75488..76129
                     /locus_tag="ACL3EZ_000450"
     CDS             75488..76129
                     /locus_tag="ACL3EZ_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0392080.1"
                     /translation="MFKNFNNIWLKRKIVLLLRIVLMMILINYLLSTAVQKQDAVIFF
                     KRELISIFSYNDYSEANLEIPKLLLNLSLFMVGWLSVILLESDLADHYHHLIRYQSSS
                     FFDYTRKRLVVISKFFTQDLFVWFLGLLPLGIHFKTVALFFLLAQLMMLYLLLSYLIA
                     LISAGAGFSFFLYFLAFVGQEWMMDHIVTVYLVLLSLLVMLILSRLEEKFKKG"
     gene            76133..76783
                     /locus_tag="ACL3EZ_000451"
     CDS             76133..76783
                     /locus_tag="ACL3EZ_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGR0392081.1"
                     /translation="MRLEIINGQKIYGKRPILNQLNLVFQSGKIYGLKGDNGSGKTVL
                     LKILAGYIKLDKGKVLQDGKVYGVKNHYIQDAGILIEKVEFLSHLSLRENLELLRYFS
                     SKVTEKRIAYWIQYYDLQEFEDVEYRHLSLGTKQKMALIQAFISSPSILFLDEPMNAL
                     DEKSVRLTKQVILSYLKKENGLVILTSHISEDISDLCTDVLVVENGHIQYVKDIQS"
     gene            76794..77081
                     /locus_tag="ACL3EZ_000452"
     CDS             76794..77081
                     /locus_tag="ACL3EZ_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000940707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0392082.1"
                     /translation="MAHLKSFITRYSKVYIGLVLLIWLSFFFIPWDRAILGVRIDIFI
                     IQKVLLVFGILSILMALLSKKVSLFVFGLICCLSLWINLFITFAILPIFGN"
     gene            77227..79740
                     /gene="secA"
                     /locus_tag="ACL3EZ_000453"
     CDS             77227..79740
                     /gene="secA"
                     /locus_tag="ACL3EZ_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HGR0392083.1"
                     /translation="MANILKTIIENDKGEIRRLEKMADKVFKYEDQMAALTDDQLKAK
                     TVEFKERYQNGESLDSLLYEAFAVVREGAKRVLGLFPYKVQVMGGIVLHHGDVPEMRT
                     GEGKTLTATMPVYLNALSGKGVHVVTVNEYLSERDATEMGELYSWLGLSVGINLATKS
                     PMEKKEAYECDITYSTNSEIGFDYLRDNMVVRAENMVQRPLNYALVDEVDSILIDEAR
                     TPLIVSGANAVETSQLYHMADHYVKSLNKDDYIIDVQSKTIGLSDSGIDRAESYFKLE
                     NLYDIENVALTHFIDNALRANYIMLLDIDYVVSEEQEILIVDQFTGRTMEGRRYSDGL
                     HQAIEAKEGVPIQDETKTSASITYQNLFRMYKKLSGMTGTGKTEEEEFREIYNIRVIP
                     IPTNRPVQRIDHSDLLYASIESKFKAVVEDVKARYQKGQPVLVGTVAVETSDYISKKL
                     VAAGVPHEVLNAKNHYREAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCV
                     IGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMKRFGSERLKGIFERLNMSE
                     EAIESRMLTRQVEAAQKRVEGNNYDTRKQVLQYDDVMREQREIIYTQRYDVITADRDL
                     APEIQAMIKRTIGRVVDGHARAKQDEKLEAILNFAKYNLLPEDSITMEDLSGLSDKAI
                     KEELFQRALKVYDSQVSKLRDEEAVKEFQKVLILRVVDNKWTDHIDALDQLRNAVGLR
                     GYAQNNPVVEYQAEGFRMFNDMIGSIEFDVTRLMMKAQIHEQERPQAERHISTTATRN
                     IAAHQASMPEDLDLSQIGRNELCPCGSGKKFKNCHGKRQ"
     gene            79821..80852
                     /locus_tag="ACL3EZ_000454"
     CDS             79821..80852
                     /locus_tag="ACL3EZ_000454"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000232189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HGR0392084.1"
                     /translation="MVFTAKSSKINIEEVRALSKLEGQALERKSQRDQELEAIIRGED
                     QRILLVIGPCSSDNEEAVLEYAKRLAVLQEEVADRIFMVMRVYTAKPRTNGDGYKGLI
                     HQPNATEAPSLINGIKAVRHLHYRVITETGMTTADEMLYPENLPLVDDLISYMAVGAR
                     SVEDQQHRFVASGAGFSTGFKNPTSGNLNVMFNGIYAAQNKQSFLFLGKEVETTGNPL
                     SHAILRGALNEYGKNIPNYYYDNLIDTIAQYEKMGLENPFIIIDTNHDNSGKQYIEQI
                     RIVRQTLINRAWNEKIKQFVRGFMIESYLEDGRQNEPEVFGKSITDPCLGWDNTEALV
                     REIYKTLGE"
     gene            80854..81885
                     /locus_tag="ACL3EZ_000455"
     CDS             80854..81885
                     /locus_tag="ACL3EZ_000455"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HGR0392085.1"
                     /translation="MAFIEKGQEIDMEVIKAETQLSAEALRLKESRDRELADIISGED
                     DRILLVIGPCSSDNEEAVLEYARRLSALQKKVADKIFMVMRVYTAKPRTNGDGYKGLV
                     HQPDTSKAPSLINGLQAVRQLHYRVITETGLTTADEMLYPSNLILVDDLVSYHAVGAR
                     SVEDQEHRFVASGIDAPVGMKNPTSGNLGVMFNAIYAAQNKQTFLYHGQEVETSGNPL
                     AHVILRGAVNEYGNYMPNYYYENLLQAIERYETMGLENPFILIDTNHDNSGKQYMEQI
                     RIVRQTLQNRDWNEKIKKTVRGFMIESYLADGRQNQPEIFGCSITDPCLGWENTEALV
                     EEIYVTLTK"
     gene            81930..82292
                     /gene="acpS"
                     /locus_tag="ACL3EZ_000456"
     CDS             81930..82292
                     /gene="acpS"
                     /locus_tag="ACL3EZ_000456"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008897 - holo-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_process: GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HGR0392086.1"
                     /translation="MIVGHGIDIEELASIESAVTRHEGFAKRVLTAQEMERFTSLKGR
                     RQIEYLAGRWSAKEAFSKAMGTGISKLGFQDLEVLNNERGAPYFSQAPFSGKIWLSIS
                     HTDQFVTASVILEENHES"
     gene            82282..83385
                     /gene="alr"
                     /locus_tag="ACL3EZ_000457"
     CDS             82282..83385
                     /gene="alr"
                     /locus_tag="ACL3EZ_000457"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000648075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008784 - alanine racemase activity
                     [Evidence IEA];
                     GO_process: GO:0006522 - alanine metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HGR0392087.1"
                     /translation="MKASPHRPTKALIHLGAIRQNIQQMGAHIPQGTLKWAVVKANAY
                     GHGAVAVAKAIQDDVDGFCVSNIDEAIELRQAGLSKPILILGVSEIEAVALAKEYDFT
                     LTVAGLEWIQALLDKEVDLTGLTVHLKIDSGMGRIGFREVSEVEQAQDLLQKHGVCVE
                     GIFTHFATADEESDDYFNAQLERFKTILASMKEVPELVHASNSATTLWHVETIFNAVR
                     MGDAMYGLNPSGAVLDLPYDLIPALTLESALVHVKTVPAGACMGYGATYQADSEQVIA
                     TVPIGYADGWTRDMQNFSVLVDGQACPIVGRVSMDQITIRLPKLYPLGTKVTLIGSNG
                     DKEITATQVATYRVTINYEVVCLLSDRIPREYY"
     gene            83404..85419
                     /gene="recG"
                     /locus_tag="ACL3EZ_000458"
     CDS             83404..85419
                     /gene="recG"
                     /locus_tag="ACL3EZ_000458"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HGR0392088.1"
                     /translation="MNLHQPLHVLPGVGPKSAEKYAKLGIENLQDLLLYFPFRYEDFK
                     TKQVLELEDGEKAVLSGQVVTPASVQYYGFKRNRLRFSLKQGEVVFAVNFFNQPYLAD
                     KIELGATLAVFGKWDRAKASLTGMKVLAQVEDDLQPVYRLAQGISQASLVKVIKTAFD
                     QGLDLLIEENLPQSLLDKYKLMSRCQAVRAMHFPKDLAEYKQALRRIKFEELFYFQMQ
                     LQMLKSENRVQGSGLVLNWSQEKVTAVKVSLPFALTQAQEKSLQEILTDMKSDHHMNR
                     LLQGDVGSGKTVVAGLAMFAAVTAGYQAALMVPTEILAEQHFESLQNLFPNLKLALLT
                     GSLKAAEKREVLETIAKGEADLIIGTHALIQDGVEYARLGLIIIDEQHRFGVGQRRIL
                     REKGDNPDVLMMTATPIPRTLAITAFGDMDVSIIDQMPAGRKPIVTRWIKHEQLPQVL
                     TWLEGEIQKGSQAYVISPLIEESEALDLKNAIALSEELTTHFAGKAEVALLHGRMKSD
                     EKDQIMQDFKERKTDILVSTTVIEVGVNVPNATVMIIMDADRFGLSQLHQLRGRVGRG
                     DKQSYAVLVANPKTDSGKDRMRIMTETTNGFVLAEEDLKMRGSGEIFGTRQSGLPEFQ
                     VADIIEDFPILEEARKVASYISSIETWQEDPEWRMIALHLEKKEHLD"
     gene            85736..86716
                     /locus_tag="ACL3EZ_000459"
     CDS             85736..86716
                     /locus_tag="ACL3EZ_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylxylan esterase"
                     /protein_id="HGR0392089.1"
                     /translation="MKNPALLEEIKTYRGRDEVPEDFDDFWDGEVKNVSTLPSYHLEE
                     RDFHIPQVKCYELTFEGSKKGKVYARIVLPKSEEKVPLIFHFHGYMGRGWDWADMLGF
                     TVAGYGVVSMDVRGQSGYSQDGLRSPLGNTVKGHIIRGAVEGRDHLFYKDVYLDIYQL
                     VEIVASLSQVDEKRLSSYGASQGGALALVAAALNPRIQKTVAIYPFLSDFRRVIEIGN
                     TSEAYDELFRYFKFHDPFHETEEEIMATLAYIDVKNLAHRIQGEVKMITGLDDDVCYP
                     ITQFAIYNRLTCDKTYRIMPEYAHEAMNVFVNDQVYNWLCGSEIPFKYLK"
     gene            87521..87748
                     /locus_tag="ACL3EZ_000460"
     CDS             87521..87748
                     /locus_tag="ACL3EZ_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0392090.1"
                     /translation="MIFKAFKTKKQRKRQVELLLTVFFDSFLIDLFLHLFGIVPFKLD
                     KILIVSLIIFPIISTSIYAYEKLFEKVFDKD"
     gene            88036..91038
                     /gene="nanA"
                     /locus_tag="ACL3EZ_000461"
     CDS             88036..91038
                     /gene="nanA"
                     /locus_tag="ACL3EZ_000461"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored neuraminidase NanA"
                     /protein_id="HGR0392091.1"
                     /translation="MNRSVQERKCRYSIRKLSVGAVSMIVGAVVFGTSPVLAQEGASE
                     QPLANETQLSGGSSTLTDTEKSQPSSETELSGNKQEQERKDKQEEKIPRDYYARDLEN
                     VETVIEKEDVETNASNGQRVDLSSELDKLKKLENATVHMEFKPDAKAPAFYNLFSVSS
                     ATKKDEYFTMAVYNNTATLEGRGSDGKQFYNNYNDAPLKVKPGQWNSVTFTVEKPTAE
                     LPKGRVRLYVNGVLSRTSLRSGNFIKDMPDVTHVQIGATKRANNTVWGSNLQIRNLTV
                     YNRALTPEEVQKRSQLFKRSDLEKKLPEGATLTEKTDIFESGRNGKPNKDGIKSYRIP
                     ALLKTDKGTLIAGADERRLHSSDWGDIGMVIRRSEDNGKTWGDRVTITNLRDNPKASD
                     PSIGSPVNIDMVLVQDPETKRIFSIYDMFPEGKGIFGMSSQKEEAYKEIDGKTYQILY
                     REGEKEAYTIRENGTVYTPDGKATDYRVVVDPVKPAYSDKGDLYKGDQLLGNIYFTTN
                     KTSPFRIAKDSYLWMSYSDDDGKTWSAPQDITPMVKADWMKFLGVGPGTGIVLRNGPH
                     KGRILIPVYTTNNVSHLDGSQSSRVIYSDDHGKTWHAGEAVNDNRQVDGQKIHSSTMN
                     NRRAQNTESTVVQLNNGDVKLFMRGLTGDLQVATSKDGGVTWEKDIKRYPQVKDVYVQ
                     MSAIHTMHEGKEYIILSNAGGPKRENGMVHLARVEENGELTWLKHNPIQKGEFAYNSL
                     QELGNGEYGILYEHTEKGQNAYTLSFRKFNWDFLSKDLISPTEAKVKRTREMGKGVIG
                     LEFDSEVLVNKAPTLQLANGKTARFMTQYDTKTLLFTVDSEDMGQKVTGLAEGAIESM
                     HNLPVSVAGTKLSNGMNGSEAAVHEVPEYTGPLGTSGEEPAPTVEKPEYTGPLGTSGE
                     EPAPTVEKPEFTGGVNGTEPAVHEIAEYKGSDSLVTLTTKEDYTYKAPLAQQALPETG
                     NKESDLLASLGLTAFFLGLFTLGKKREQ"
BASE COUNT        27906 a        16530 c        20213 g        26809 t
ORIGIN      
        1 gtgcatcagc ctcagcatcg acaagcgctt cggcttcagc aagtacaagt gcgtctgagt
       61 cagcatcgac aagcgcttcg gcttccgcaa gtacaagtgc gtctgagtca gcatcaacaa
      121 gtgcttcggc ttccgcaagt acaagtgcgt cagtctcagc gtcgacaagt gcgtcggctt
      181 cagcaagcac aagcgcctca gcttcagcgt caacgagtgc gtctgagtca gcatcgacaa
      241 gcgcttcagc ttcagcatca acgagtgcgt cggcttcagc aagtacaagt gcctctgaat
      301 cggcatcaac cagtgcttca gcctcagcat cgacaagcgc ttcggcttca gcaagtacaa
      361 gtgcgtctga gtcagcatca acaagtgcgt ctgaatccgc atcaacgtct gcctcagcct
      421 cagcgtcaac cagtgcgtca gcttcagcgt caacgagtgc gtcggcttcc gcatcaacaa
      481 gcgcctcggc ttcagcaagt accagcgcct cagcctcagc aagcaccagc gcctcggctt
      541 cagcaggtaa gtcaagacag caattgccaa atacaggtac agaagtttcc aagtcatctg
      601 tagcaagtac ctcagcgtct gaatcggcct caacaagtgc ctcagcctca gcaagtacca
      661 gtgcatcagc ttcagcaagt acctcagcgt ctgaatcggc ctcaaccagt gcttcagcct
      721 cagcatcgac aagcgcttca gcttcagcaa gcaccagtgc ttcggcttcc gcatcaacca
      781 gtgcttcagc ctcagcatcg acaagcgctt cagcttcagc aagcaccagt gcttcggctt
      841 ccgcatcaac aagtgcttca gcctcagcat cgacaagcgc ttcagcttca gcaagcacct
      901 cagcttctga atcggcatca accagcgcgt cggcttcagc aagtactagt gcgtcggctt
      961 cagcatcgac aagcgcctca gcttcagcat caacgagtgc atcggcttca gcatcgacaa
     1021 gcgcatcagc ttcagcatca acgagtgcct cagccttagc atcaacgagt gcttcagctt
     1081 cagcatcaac aagcgcctca gcttcagcaa gtacctcagc ttctgaatcg gcctcaacaa
     1141 gtgcctcagc ttcagcaagc acctcagcgt ctgaatcggc ctcaacaagt gcgtcggctt
     1201 cagcgtcaac cagtgcttcg gcctcagcat cgacaagtgc gtcggcttca gcgtcaacca
     1261 gtgcgtcggc ttcagcaagt acaagcgcct cagcttcagc ctcaacgagt gcctcagctt
     1321 cagcaagtac aagtgcgtct gagtcagcat caacgtctgc ctcagcctca gcgtcaacaa
     1381 gtacctcagc gtctgaatca gcatcaacca gtgcctcagc ttcagcctca acgagtgcct
     1441 cagcttcagc ctcaacgagt gcgtcggctt cagcaagtac cagtgcctca gcctcagcaa
     1501 gtactagtgc ctcaacttca gcatcaacca gtgcgtctga atctgcatca acgagtgcgt
     1561 cagcctcagc atcaacaagt gcctcagctt cagcctcagc aagcacaagc gcatcagtct
     1621 cagcaagtac ctcagcgtct gaatcggcat caacgagtgc ctcagcttca gcaagcacct
     1681 cagcgtctga atcggcatca accagtgcgt cggctttagc gtcaacgagt gcgtcagctt
     1741 ccgcgtcgac aagcgcctca gcttcagcat caacgagtgc ctcagcctca gcaagcacat
     1801 cagcatctga atcagcgtca accagtgcgt cagcctcagc aagtaccagc gcatcagtct
     1861 cagcatcaac gagtgcgtcg gcttcagcaa gtacaagtgc gtctgagtca gcatcaacga
     1921 gtgcgtcggc ttcagcgtcg acaagcgcct cagcttcagc atcaacgagt gcctcagctt
     1981 cagcatcaac gagtgcctca gcttcagcat tgacaagcgc ctctgaatct gcatcaacaa
     2041 gcgcatcagc atcagcatcg acaagcgcct cagcttcagc gtcaaccagc gcctcagctt
     2101 cagcatcaac gagtgcctca gcttcagcgt caacgagtgc ctcagcttca gcgtcaacca
     2161 gcgcaagtac atcagcaagc acaagtgcat cagcctcagc aagcacaagt gcttcagctt
     2221 cagcgtcaac cagcgcctcg gcctcagcat caacgagtgc ttcagcttca gcaagcacaa
     2281 gcgcctcagc ttcagcgtca acgagtgcgt cggcttcagc atcaacaagt gcgtcagctt
     2341 cagcaagtac cagcgcctca gcttcagcgt caacgagtgc ctctgaatcg gcctcaacca
     2401 gtgcatcagc ttcagcgtca accagtgcat cagtctcagc atcaacgagt gcttcagctt
     2461 cagcgtcaac cagtgcatca gcttcagcaa gtaccagcgc ctcagcttca gcgtcaacga
     2521 gtgcctcagc ctcagcatcg acaagtgcct cagcttcagc atcaacgagt gcttcagctt
     2581 cagcgtcaac gagtgcttca gcttcagcaa gcacaagcgc ctcagcttca gcgtcaacga
     2641 gtgcgtcggc ttcagcaagt acaagtgcct ctgaatcggc ctcaaccagt gcttcagcct
     2701 cagcatcgac aagcgcttcg gcttcagcaa gtacaagtgc gtctgaatcc gcatcaacgt
     2761 ctgcctcagc ctcagcgtca accagtgcgt cagcttcagc gtcaacgagt gcgtcggctt
     2821 cagcgtcaac gagtgcgtct gagtcagcat cgacaagcgc ttcagcttca gcatcaacga
     2881 gtgcgtcggc ttcagcgtct gaatcggcat caacaagcgc aagcgcgtca acttcagcag
     2941 gtaagtcaag acagcaattg ccaaatacag gtacagaagc ttccaagtca tctgtactcc
     3001 ttggagcttt ggcagctgtg actggcttgg gtttgtttgc gaaacgccgt aaacgtgatg
     3061 atgaagaata atcggattag aaaaggtagt ttatcaagag tttggacaga aaagtggatg
     3121 catgcattgg ttgatgccat gtccgaacgc attacgctac tagctaatat gggttaccct
     3181 ttagaaaagc atttggcgat ttatcgtcaa atgttggaat tcagtctcgc caacggtcaa
     3241 gctagtggtt tatctgacac agcaacgtat aaagagtttg aaatgaaaaa aagactttta
     3301 aatcagttaa cggtacaaga atcaagtgaa aagaaagcca ttgtcctagc ggcgaattat
     3361 gcctatgtag accaagtttt aacgacaatc aggtctatct gttaccacaa tcgctcgctt
     3421 cgtttttatt tgattcatag cgattttcca aatgaatgga tcaaacaatt aaataagcga
     3481 ttagagaagt ttgactcaga aattattaat tgtcgggtaa cttctgagca aatttcatgt
     3541 tataaatcgg atattagtta cacagtcttt ttacgctatt tcatagctga tttcgtgcaa
     3601 gaagacaagg ccctctactt ggactgtgat ctagttgtaa cgaaaaatct ggatgacttg
     3661 tttgctacag acttacaaga ttatcctttg gctgctgtta gagattttgg gggcagagct
     3721 tattttggtc aagaaatctt taatgccggt gttctcttgg taaacaatgc tttttggaaa
     3781 aaagagaata tgacccaaaa attaattgat ttaaccaatg aatggcatga taaggtggat
     3841 caggcagatc agagcatctt gaatatgctt tttgaacata aatggctgga attggatttt
     3901 gattataatc atattgtcat tcataaacag tttgctgatt atcaattgcc tgagggtcag
     3961 gattatcctg ctattattca ctacctttcc catagaaaac cgtggaaaga tttggcggcc
     4021 caaacttatc gtgaagtttg gtggtactat catgggcttg aatggacaga attgggacaa
     4081 aaccatcatt tacatccatt acaaagatct cacatctatc caataaagga acctttcact
     4141 tgtctaatct atactgcctc agaccatatt gaacaaattg agacattggt tcaatccttg
     4201 cctgatattc agtttaagat agcagctaga gtaatagtta gtgatcgatt ggctcagatg
     4261 acaatttatc caaacgtgac tatatttaac ggaattcact atttggtaga tgtcgataat
     4321 gaattggtag aaaccagtca agtactttta gatattaatc atggcgaaaa gacagaagaa
     4381 attctcgatc aatttgctaa tcttggcaag cctatcttat cctttgaaaa tactaaaacc
     4441 tatgaagtag gtcaggaggc atatgctgtt gaccaagttc aagcaatgat tgagaaattg
     4501 agagaaataa gcaaatgaag aaaaatcatt tagtaggaga tgctctgatt ttgacggtta
     4561 gtgatcagat tgaagagttg gattatctcc ttgaatcctt gtcaaatatc tgttttcata
     4621 ttgcagcacc tgttcaattt tccgagaaaa tccgtagctt agaaacgaac tataatgtcc
     4681 gtctccgaac gattacaaat gaagaacagc taaacttttt agtcgatacc tgtgactttt
     4741 tactagatat caatcacttt caagaagtag atgctattgt ctccaagttt gtacaggctg
     4801 gaaaatctgt ctttgcattt gacaatacag tccatggaaa tcaggggcag gaagtttttc
     4861 tatcaagtac accagacaaa ttggtttcta gagtgagaga ctatctgaat gaagtcagag
     4921 taggcaccaa tcatcaagag aaaatcattc aagatgggac ttggaatgtc tttaaaatcg
     4981 atgataaggc tcacttcatt gtaggagcca atgtcgcctg tagaaatttt gaaaattttc
     5041 atgtctcttc tggtaagtta atcctgaata atggtgtttt tatcaacaac tcttgtagtt
     5101 ttaactgtat ggaaagaatt gaaatcggag ctggtaccat gatgggagag ggtgttcgtt
     5161 tttatgatca cgaccatatt tataccgctg aaaagattga aaagtggcag tggactacag
     5221 cgccgattag agttggcaga gactgctgga taggaagtaa tgtcacgatt ttaaaaggag
     5281 tgacgattgg agataatacc attattggag caggttgtct catacgcaat gatattccat
     5341 caaacagtgt agtttataat aatggaaatc tttttgtaaa gatgagagtt taatgagtaa
     5401 tataaaatca agttagatga aactttctaa ggttggaaga aaaccaaaca tgacttcaga
     5461 ggatatctta atggtgagtc tttaatctat ttgataatgc cgaatctata agtagatagt
     5521 tgtaaatttt gcagaacacg aaagaaatct tattcatagc ataattgatt tgaagatttt
     5581 ttgattcaac atttagattt agaaatgaaa agatatcatc gaagaaaagg atactgtaat
     5641 tgttgatgaa acagaagtaa aaaatcaata tctcaaaagt agaaatcacg ttttttcagt
     5701 tggtaaaata gatgatttgt ttataaaata gaaaaatcgg gagataagaa tgtatagaaa
     5761 agttattgct ttaggagctg atattcatta tcttgataag gtagaaaccg ttataaagtc
     5821 agtttcagtt cataatcacg aagtgaaatt ttatgtgttt aatgatgatc tgcctagtga
     5881 atggtttctt ttgatgagaa atcgtctgaa ggttattggt tctgagatta ttaatgtcaa
     5941 aaaagcagat cacaatcttc gtgatttcca cttgccaaat gcaatcctgt cctatgcaac
     6001 tttctttagg tatttcatag cagacgaagt gcttgaagat cgggtactct acttagactc
     6061 ggatatcatt gtgaatgcca atttggatga attatttttt ttggatttgc aaggatacgc
     6121 tatcgcagct gttcaagatt ttgatcaaga tggttggtta acaacattta attcaggtat
     6181 gttattgatt gatgcaaaaa aatggcgaga aaaaaaatca acacaaaatt tgctagagtt
     6241 gactgctcaa caccatgaac atgtctatgg ggaccaaggt gttctcaata tatatttcgg
     6301 tgaccagtgg ctacatttgg acaaagagta taatttcatg gttggtttag atcagttttt
     6361 acatttaaaa ggtaatgctg actggtacca atccaactat tatggaaatt acgagcctaa
     6421 gattgtccat tatactacag agttcaaacc gtggactcat ttaacactta cacgttttcg
     6481 taaactctgg tggttttatt atggattgaa ctggaacgat gtgttgttaa gttcagatat
     6541 cgttaaacgc tcttttaagg agttagtggg tgttccctta tatcatactt gtatttttac
     6601 aaatagtgcc gcaatggagt ccttggaata tctcctatcg gaattgccag aagtgcactt
     6661 tacgatcttg gcgcatacaa attttgctcc ctctgttgtt gatttacaga gatatctgaa
     6721 tctttcactt tttccaaatt ttaattcttt taatatgaaa gaaaccttgg ataagatgga
     6781 tttctatctt gatattaacc atgaaggaga gattgtcaac attatagaag aagtctgtag
     6841 gcgcaataag ccaatcttta gttttgataa tactagtcat gatagcaaag gaagaagtcg
     6901 gattttttca gcaactgagc cagataagat ggtagatgct attcgcaaat ttttaggaga
     6961 ataagtcaat ggagaatgag ttaatcagta ttgttgttcc aatatataat gtggaaaatt
     7021 atctgagaat gtgtttggat agcattcaga atcagacgta tcaaaatttt gagtgtttat
     7081 taatcaatga tggctctcca gatcattcat ccaaaatatg tgaagaattt gtagagaaag
     7141 attctcgttt caaatatttt gagaaagcaa acggcggtct ttcatcagct cgtaacctag
     7201 gtattgaatg ttcggggggg gcgtacatta cttttgtaga ctctgatgat tggttggaac
     7261 atgatgcttt agaccgatta tatggtgctt tgaaaaagga aaacgcagat attagtatcg
     7321 ggcgttataa ttcttatgat gaaacacgct atgtgtatat gacttatgtt acggatccag
     7381 atgattctct agaagtgata gaaggtaaag caattatgga tagggaaggt gtcgaagaag
     7441 tcagaaatgg gaactggact gtagctgtct tgaagttatt caagagagag ttactacaag
     7501 atttaccatt tcctatagga aaaattgcag aggatactta ctggacatgg aaggtacttc
     7561 taagagcttc gaggatagtc tatttgaatc gttgtgttta ctggtaccgt gttggtttat
     7621 ctgatacttt atcgaataca tggagtgaaa agcgtatgta tgatgaaatt ggggctaggg
     7681 aagaaaagat agctatttta gcaagttcag actatgactt gaccaatcat attttgattt
     7741 ataaaaatag attacaaaga gtagtagcaa aattagaaga acaaaatatg cagttcacag
     7801 agatttatag aagaatgatg gaaaaattgt ctttacttcc gtagatagta ataaaaaatg
     7861 agatagcgta atatgaaatt acatttaaca aatttatacg gcatggctgg tgatagtacg
     7921 gttatcttag ctcaaaatgc tgttcaaaag atagctagtc aactgggatt tagagaggtt
     7981 ggtatttatt tttacaacat tgcttcagat agtccttctg aaatgaataa gcgtctggat
     8041 ggtattatgg ccagtatctc tattggtgat atcttagtct ttcagtctcc aacctggaat
     8101 ggctttgaat ttgatcgtct cttgtttgat aagctaaagg atatgcaggt gaaaattatt
     8161 tgctttatcc atgatgttgt tcccctcatg tttgatagta actattatct catgaaagac
     8221 tatatgtaca tgtataatct atcagatgtt ttgatagtgc cgtcagagag aatgaaaaca
     8281 cgcctgatgg aagaaggatt gacgactaag aagattcttg ttcaagggat gtgggatcat
     8341 cctcatgatt tatccttata cacccctgct tttaaaaaaa gaactttttt tgctggaagt
     8401 ttagagcgtt ttccagactt acaaaattgg tctcaagata cgcctttgag agtattttca
     8461 aataaagggg aggccggttc tagtgctaga aatctcagca tcgaaggatg gaaaaaagat
     8521 gaggaattgt tgctagaatt atcaaagggt ggatttggcc ttgtctgggg aacccatcaa
     8581 aatgagggag aaagtaacca atactatacc ttgaatatat ctcataaggt tagtacctat
     8641 ctaacagctg gtatcccagt gattgtaccg agcaacttat caactgctaa atttatagta
     8701 gatcaaggct tgggctttgt ggcgaatagt ctagaggaag ttcatgagat agttgataaa
     8761 atgaatctac aagaatatca agaaatgacg aatcggataa aaacctttag ttatttgcta
     8821 aaagaaggtt attttactaa aaaattattg gtagatgcaa tttaccattt gggagttgaa
     8881 taagagaaca agatgattaa aacaattgta ttagctggta atcgtaatta caccaggcag
     8941 ttagaaacaa ccataaaatc tattttatac cacaatcgag atgttaagat ttatatttta
     9001 aatcaagata tcatgccaga ttggtttcga aagccacgaa aaatagctag catgttaggt
     9061 agtgagatta tcgatgttaa actacctgaa caaactgtgt ttcaagattg gaaaaaacag
     9121 gctcacatta gttcaattgc ctatgctagg tattttatcc cagattatat acaagaagat
     9181 acggttttgt atttagattg tgacttgctt atcaatgata aattagatag tctatttgag
     9241 caggatgtaa gagaacatta tatcgcagcg attagagatg caaatggtca aggttttaat
     9301 actggtgttc tactaatcaa caatgaaaaa tggcgtcaag agaaattaaa agaacgacta
     9361 attgaacaga gcattgttac aatgaaggaa gttgaagaag gccgtttcga gcattttaat
     9421 ggtgatcaaa cgatttttaa tcaggtctta caagatgatt ggttagaact aggtcgagct
     9481 tataatttac aagtagggca tgatattgtg gctttgtata acaattggca ggaacatctg
     9541 gcttttaatg ataaaccagt ggtgattcat tttacgacct acagaaaacc ctggaccacc
     9601 ttgacagcca atcgttatcg tgatttatgg tgggaattcc atgatttgga gtggaatcag
     9661 attttacaac atcatttggg agaatttgaa ctaatatcgc ctctagataa ggaattttct
     9721 tgcttaacct taacgaattc ccaagattta gaaggaatag aagagctagt tacagctcta
     9781 cctgaggtgg tatttcatat cgcagcttgg acggatatgg gagataaatt aaaaaaatta
     9841 gctgtatata ataatgtgag attgcatcca caaattgttc ctcctgtatt agataagctg
     9901 aaaaagtcaa caaatctata tttggatatc aatcatggta gtgcagatga gaacttttta
     9961 aaatctttgc aagaacaaga aaaaacgcta ctagcttttc aatcgactca gcacggagag
    10021 ttaggacaaa tcgttttcga aaatgggaaa gtttccttta tgattgatac gattaaagat
    10081 tttaagaaaa acggacatct tacctgtttt cgacaacttc caagtttaac ttgtttaacg
    10141 tttacggctt ctcaggatat cgaacaattg gattacttgg ctggacagtt gccaaatgtt
    10201 gtttttcaag ttgctgcttg gacagctatg gggccaaaat tatatgattt gtctaatcgt
    10261 tatcctaata ttcagctcta tccggcaatt tctagagata agctagacga gttgaaggag
    10321 aagatggatg cttatttaga tatcaaccta ctgacttcaa catccgatat cgttgcagaa
    10381 atggctcatc tatctaaacc tatactagcc ttttataaat ctcaaaatgg gaataatggc
    10441 caaaggttgt attcaagtga acatcctgaa cgaatgttgg ctgatttgca aaaattgata
    10501 actaaggata tgctagaaaa accgcttgat ataatccagg tgaaagggat agatgaaacc
    10561 ttggattata ttattgaaca caactcttct ttagttcgtt ttggagacgg agaagtcaat
    10621 ttgatgtggg gtttgcctat accttatcaa aatcatgatc tagagttagc taaccaatta
    10681 aaacatattg tgggtcttga gagtgacgag aaattagtgg tttgtttacc tgatgctttt
    10741 gacgatcgtt ttgtctttac ttggtgggct acaccattct ggaaagaaca tatgaatgtt
    10801 tatatggatt tttataaaga gttgtgtaag ggttcatggt atggctctac ctttatctcg
    10861 cgtccataca ttgattatga agataagagt aaggcaaaag gacaatttga aaagctaaag
    10921 agtatttggg agaataggga tattctgatt gtagagggga ttacatctcg ctctggggtt
    10981 ggaaatgatt tatttgataa ggtcaaatct gtgaaacgga ttatttgtcc atctcataat
    11041 gcttattccg ttgtcgataa cattcaagag gaaattatga aacatgctga aggaagactg
    11101 attttatgta tgctgggtcc tacagcaaaa gttttagcct atcatttaag tcgaaagggt
    11161 taccaagtct tagatattgg gcatattgac tccgagtatg agtggatgaa gatgggtgct
    11221 aaaactaagg ttaaattttc acataaacat acagcagagt ataattttga tcaagatatt
    11281 cagttcattg aggatgaaac ctataacagt cagattttag ttgatttatc aaagagagaa
    11341 gtatgaaaga tttaataagt gttatagtac cagtttataa cgtagaacca tttatttcta
    11401 gctgcttaga cagtttatcg aaacagattt atcaaaattt tgaagtttta ttagtaaatg
    11461 atggctctac agataattca ggagcaatat gtcgagagta tgctgatcgt gatagtcgtt
    11521 ttcactattt cgaaaaagaa aatgctgggg tagcggatgc acgtaatttt ggaatcgaga
    11581 gatctaaagg agattatatt acttttgtag actcagatga ttgggttact gaagagtatt
    11641 tatcaattct tatagaaact ttgaaggagc agcattctga aattgttgtt tcaacttatt
    11701 caacctataa tgagtcagat ggcttattct atatttacgt atttgactcc gattattatg
    11761 tgaaaaatta taattcaaaa cttctaatgg aagaacttcc tttattagag aggtatgata
    11821 tgagcttttt aacttcttgg ggaattctat ttaaaaggga attatttcaa gaagttcagt
    11881 ttccgtttgg tcgggtgtgt gaggatatag gaaccaatta taaattattt atgcaggttg
    11941 agaaagtaac ctatattaat aaagttttgt attggtatag ggttgggaaa gaaggacttt
    12001 ctaattctta ttcaccgaag atgatgcgtg atgattgtga ttttaggtta gaacgaattg
    12061 ccgtgctagc gctaaaagga tatgatgtca gtaaatattt agaccagatg aagttctatt
    12121 tgaaatatcg tcatgatatt gcaattcaac gagaacttaa ggagaatgtg gaaacaagac
    12181 atttagaaat gttagactat ttattgaatg gtaataaata taactgaaaa ttaagataga
    12241 gagacgataa aatgttacaa gataagaaat ctgtagtatt tgcaggtgat tacgcttata
    12301 ttcgacaaat cgaaacggcg atgaagtcac tctgtagaca caatagtcat ttgaaaattt
    12361 atctgctaaa tcaggacatt cctcaggaat ggtttagtca aataagaata tatttacaag
    12421 agatgggggg cgacttgatt gactgcaagt taattggctc acagtttcaa atgaattggt
    12481 ctaataaatt acctcatatc aatcatatga catttgcacg ctattttatt ccagattttg
    12541 taacagaaga taaagttctc tatctagata gtgatttgat tgtgactggt gatttgaccg
    12601 atttgtttga attagactta ggtgaaaatt atttggcagc agctcgttct tgctttggag
    12661 caggagtcgg cttcaatgct ggtgttctct tgattaacaa caaaaaatgg ggatctgaaa
    12721 ctattcgaca aaaattgatt gacttaacag aaaaagaaca tgagaatgtg gaagaaggag
    12781 accagtcaat tttgaatatg ttgtttaaag atcaatatag ttcccttgaa gatcaatata
    12841 attttcaaat aggatatgat tatggggcgg cagcctttaa acatcaattc atttttgata
    12901 ttccgctcga accactgcca ctaattttac actatatttc tcaggataag ccttggaatc
    12961 aattttctgt tggacgtcta agagaagttt ggtgggaata ctctttgatg gattggtctg
    13021 ttattttaaa tgaatggttt tcaaagagtg tgaagtatcc tagtaaatca caaatattta
    13081 agttgcaatg tgttaattta acgaattctt ggtgtgtcga gaaaatcgat tatttggcgg
    13141 agcaattgcc agaagttcat tttcatattg ttgcttatac aaatatggca aatgaactac
    13201 tagctttaac gcgttttcct aatgttaccg tatatccaaa ttccttacca atgttattgg
    13261 aacaaatagt aatagcttca gatttgtatt tggatttgaa tcatgatcga aaattagaag
    13321 atgcatatga gtttgtgctt aagtacaaaa aaccaatgat agctttcgac aatacttgct
    13381 ctgaaaatct ttctgagatt tcatatgaag gtatctatcc aagctccatt ccgaaaaaaa
    13441 tggttgcagc aatcagatct tacatgaggt agagaacagt atgagaaaat caatagtatt
    13501 agcggcagat aatgtctatc ttattccttt agagacgact ataaagtctg tattgtatca
    13561 caatagagat gttgattttt atattctcaa cagtgatata gctcctgaat ggtttaaatt
    13621 attggggaga aaaatggaag ttgtgaattc tacaattcgc agtgtacaca ttgataaaga
    13681 actttttgaa agctataaaa caggacctca tataaattat gcttcttact ttagattttt
    13741 tgcgacagaa gtggttgaat ctgatagggt attgtatctg gattccgata tcattgtaac
    13801 tggggaacta gctactttgt ttgagataga tctcaaagga tattcaattg gtgctgttga
    13861 tgatgtctat gcctatgaag gacgaaaatc tggatttaat tctggagttt tattaatgga
    13921 tgttgcaaaa tggaaagaac actctattgt caatagttta ttggaattag cggccgagca
    13981 aaatcaagtt gttcatcttg gggatcagag tattttaaat atttattttg aggataattg
    14041 gctagcctta gataaaacat ataattatat ggtaggtgtt gatatttatc accttgctca
    14101 agaatgtgaa cgtctagatg acaatccacc tacaattgtt cactatgcta gtcatgataa
    14161 accttggaat acatatagta tatctagact acgtgaatta tggtgggttt atagagattt
    14221 ggattggtca gagattgctt ttcaacgttc cgatttaaat tattttgaaa gaagcaatca
    14281 gtctaaaaaa caagtgatgc ttgtgacatg gagtgcagat ataaaacatt tagagtattt
    14341 agtacaacgg ttacctgatt ggcattttca tttggctgca ccgtgtgatt gttctgagga
    14401 gctgacctct ctatcacagt atacgaatgt aacagtatat caaaatgtat tacatagtag
    14461 aattgattgg ctattggacg attctatagt ttatttagat attaatacag gtggagaggt
    14521 ttttaatgta gttacaaggg cacaagaaag tggcaagaaa atcttcgctt ttgatatcac
    14581 acgtaaaagt atggatgatg gactctatga cggtattttt tctgtggaga gaccagatga
    14641 tttagtggat agaatgaaga atatagagat agagtaatga gtgaattaat tagtgttgtg
    14701 gtaccgatat acaatacggg aaaatattta gtggagtgtg tcgagcatat tctgaagcaa
    14761 acctatcaaa atatagaaat tattttagtt gatgacggtt ctacggataa ttctggggaa
    14821 atttgtgatg cttttatgat gcaagataat cgtgtgcgag tattgcatca agaaaataag
    14881 ggggggggca gcacaagcta aaaatatggg gattagtgta gctaagggag agtacatcac
    14941 gattgttgat tcagatgata tcgtaaaaga aaatatgatt gaaactcttt atcagcaagt
    15001 ccaagaaaag gatgcagatg ttgttatagg gaattactat aattatgacg aaagtgacgg
    15061 gaatttttat ttttatgtaa cagggaaaga tttttgcgtc gaagaattag ctatacaaga
    15121 aattatgaac cgtcaagcag gagattggaa attcaatagc tcggccttta tattgccgac
    15181 atttaagttg attaaaaaag aattattcaa tgaagttcac ttttcaaatg gtcgccgctt
    15241 tgatgatgaa gcaactatgc atcgctttta tcttttagcc tctaaaatcg tctttataaa
    15301 cgataatctc tatctgtata gaagacgttc aggaagcatc atgagaacgg aatttgatct
    15361 ttcctgggca agagatattg ttgaagtgtt ttctaagaaa atatcggatt gtgtcttggc
    15421 tggtttggat gtctccgttc tgcgtattcg atttgtcaat cttttaaaag attataagca
    15481 aactttagaa taccatcaat taacagatac tgaggaatat aaagatattt gtttcagatt
    15541 aaagttgttt tttgatgcag aacaaagaaa tggtaaaagt tgaaataaaa gaattgttat
    15601 ttaccatatc acaaacaatg aaggtgaggg gagtgtttta tgactaagat ttattcgtca
    15661 atagcagtaa aaaaaggact atttacctta tttctactgt ttatctatgt attgggaagt
    15721 cgtattactc tcccttttgt tgacctaaat actaaagatt ttttaggagg ttcaacagcc
    15781 tatctagcct tctcagccgc cctaacaggt gggaatctaa gaagtttatc aattttttct
    15841 gttggattat ccccttggat gtccgccatg attttatggc agatgttttc tttttctaaa
    15901 cggttgggtt taacatctac gtctatagaa attcaagatc gtcgaagaat gtatctgacc
    15961 ttgctaattg ctgtgattca atccttggca gttagcttga gcttgccagt acaatcctcc
    16021 tactcggtaa ttttggttgc tctaatgaat accttgttac tcatagcagg aacgtttttt
    16081 cttgtttggt tgtcagattt aaatgctagc atgggaattg ggggttctat tgtaatcctc
    16141 ctatccagca ttgttttaaa tatccctcag gatgttattg aaacttttaa actggtttat
    16201 atccctacag ggattgttgt cttgcttgtt tttatgacca ttatattttc ttacttgctt
    16261 gcccttatgt atcgagctcg ctatttggtt cctgttaata aaattggctt acacaatcga
    16321 tttaaacgct attcttatct cgaaatcatg ttgaatcctg caggtgggat gccttatatg
    16381 tatgtgatga gttttcttag tgtaccagct tatttgttca tcttgttggg atttattttc
    16441 cctaatcatt cagggctagc ggctttatca aaggaattta tggttgggaa gcctttgtgg
    16501 gtctatgttt atatttcggt cttattttta tttagtatca tttttgcttt tgttacgatg
    16561 aatggagaag agattgcaga ccgtatgaaa aaatctggag aatacattta tggtatttat
    16621 ccaggtgcgg atactagtcg atttattaat cgattggtcc ttcgtttctc agtcataggt
    16681 ggtctcttta atgtgattat ggcaggtggt cccatgcttt ttgttttgtt tgatgaaaag
    16741 ttattacgat tggcaatgat tccaggctta tttatgatgt tcgggggcat gatttttacg
    16801 attagagacg aggtcaaggc tttaaggcta aatgagacct atagaccttt gatttaggag
    16861 acttttatgt attattttat tccagcttgg tatgggtcag aaagaacatg gcatgcagat
    16921 atcactccat ggtatttttc tcattttcgt ctagagtttg atgatacctt tcaccagatt
    16981 cggctctttc aagagcaaga tatagattct cgtctattag tattagctta ccagcctcat
    17041 ctacgttatt ttttatatag acatggtgtg ttagaaacgg atacttattc cgtttttgat
    17101 gttatgcaag attttcataa tctccatacc caagttttaa gcattagaga tattgagtgg
    17161 gatgatgact gtgaatttat ttatagtccc tttacgatta tcgttcaaaa aaatgggaag
    17221 aaatttgcta aggttgaaca tggagttgaa ggtttcatca gtgatataca gtattttgga
    17281 ccgaatggtc aaatacatat gcaccatatc atggatgatc gagggtttat atcgagtatt
    17341 attttttttg aagatgggca agcagcctat caagaatatt tgaatcctaa gggagtttgg
    17401 caatttagag agcgtttaaa agaaggagga caggtagaag tcaatccaat tttgggttat
    17461 cgctttaaaa tgcttaccta tcaaaatatg ggagatctgg tggcagaatt ttttgagaat
    17521 tatctgcaaa cgtatgtgaa ggatcaggat atttttatgc ttccttctca ttctcatcat
    17581 gaccagttgg tactagatcg tttacctagt actaatccta aactgttgag tctgttcatt
    17641 ggacgtaatc ctcaagatac ctttagggat ttagatgtaa cttttgaaaa atcggatttg
    17701 attttggtgg atagagagga tagtttacga ttgttgcagg agttgtatcc tgaacgaatg
    17761 catcaatgtt atcatttatc atcttttgac acccgattac gattgggacg aagccaaact
    17821 aagaaagaat ccatcattta ttttcaactg gattttgagc aggggattga taatcaagct
    17881 ctgcttcaag tcttgtcctt tgtcgctgaa aataaggata ctgaggtgat ttttggagcc
    17941 tttgctgcta gtcaggagca aatgaatgag gttgaaggga ttgttgagtc tttcatccaa
    18001 gaaaacattc aatccgaaaa tctgggaaag gcgattgatt atggtgatgc agaaaatcct
    18061 ctggaagaaa atcaacacca ggacttacgc ttacagtttg ttaacttgaa tgatgagtta
    18121 gatttgataa aaacactaga atttgtccgt ttgattgtgg atttaaatag acatcctcat
    18181 ctctacacac agattgctgg gattagtgca ggaattcctc aaatcaacct agttgaaacc
    18241 gtctatgttg aacatttaaa aaatggttat ttgttagcag atgttacaga attttctaag
    18301 gctgcacatt attacacaga taggttgaag gagtggaatg agtccttgat atattcaatt
    18361 gataagatta aggagcacac aggacaacaa tttcttggaa aattagagaa atggatagag
    18421 gaggttaaaa atgtcaaagg aacttaatat tttacagata ggacttgcca attgggaaaa
    18481 tcactatgac atacctgaaa atatgagttg gtattatttt tacccaaact catcaaaagc
    18541 ccttcgtgaa ataattgaaa aagaggatat taaccgtttt catgcagttt taatagaaga
    18601 tggtcagtat tccagagact tattttccta tgtaaaatat tttgaacctt atactttatt
    18661 ttataaccag aatctacaaa taaatgatag agaggttgtg gattttctaa aaaaacgatg
    18721 tgcacaagca attgattttt taagtcccca acaactaatc aatgatttaa gtaaatctct
    18781 ttttggcggt gggtatggtg ataaactctt tcctccgacg atacaagtca atccaaattt
    18841 tacaggagct atttcttatc aaggattgga ttatgtcagt ttggaaggtg agtttgggca
    18901 agattttgcc cagcttgcct attgggctta taatattatg gtgcaaaaaa cactccctat
    18961 tgagttgtgg cttgaatatg agaaggaagg caattgtgac tttcgtttag taatccgtaa
    19021 aatgtggagt gggtctgttg atgatttctt tgaagaagta atagtatctg aaaaagactt
    19081 ggagcaagca ctttttatgg atagtcgaga cggagactac tttctctcga tatctgttga
    19141 agcaagaggt cgtggaacta tcaaactagg taatcttcac caacgatgga gtcgaaaaca
    19201 atttggtaag tttgtacttg gtggaaatat cctacatgat tccaagcgtg atgaaataaa
    19261 ctatttcttc catccaggtg attttaaacc gcctttgact gtctattttg caggttatcg
    19321 acctgcagaa ggattcgagg gttactttat gatgaagact cttggatgtc ccttcatttt
    19381 attttctgat ccacgtttag aggggggagc tttttatctc ggaacggatg agctagaggg
    19441 aaaagtaaag gatacgatca ctcactatct tgattattta ggctttgatc ataaggattt
    19501 gattttatca ggtctttcta tgggaacgtt tccggctctc tattatggtg cttcttttga
    19561 accccatgcc atcatagttg gtaagccctt ggctaattta ggaactatag ctagtcgtgg
    19621 acgtttggac gcaccgggtg tctctaactt agcttttgat tgtttaattc atcatacagg
    19681 tgggacaagt tctcaagata tgacggagtt ggatcagcgt ttttggaaaa tttttaaaca
    19741 agcaaatttt tcaaagacaa cctttggttt atcctatatg aaagatgaag aaatggatcc
    19801 acaagcctat gaacaattag tgtcttatct gtgtaataca ggtgcgaaga ttttatctaa
    19861 aggaactgct ggacgacata atgatgatac agataccaat atttcttggt ttttgcactt
    19921 ttatagaatg gtcttagaga ctggttttgg aagggagaaa agatgattat tacacagaga
    19981 cagtctattc attggggaga agttggtggg acttatatgt atggaacaac tgtatcttat
    20041 taccctgaca aaagtgttcg tctgtataat cctctattgc catctggtga gattctaaag
    20101 acttggtttt ctagtgtcaa ttaccaggct gcacgaaccc aacctcagct tcccttatta
    20161 aaaagaaagc aggagtatca actatcactg gtttttgatt gtcagcctga aaatggagtt
    20221 tataccaaga taactttttt tgaccgctat ggtgatattt tagaaaaaaa ggtagaaaaa
    20281 gtgaaagatt tcatatttac ttatccagaa gatagttata cttatcaagt ttctctttta
    20341 agtgctggat ttgagtcctt aactttttat catttttcta tcaaggagat cagaagtgtt
    20401 tagacgttta ggtcaagatt tccagcttag gaaagtgaaa aagattttaa agcagattaa
    20461 tgccctgaaa ggcaagatgt cctctctttc ggatcaagaa ttagtagcta aaacagtaga
    20521 gtttcgtcag cgtctttccg agggagaaag tctagacgat attttggttg aagcttttgc
    20581 tgtggtgcgt gaagcagata agcggatttt agggatgttt ccttatgatg ttcaagtcat
    20641 gggagctatt gtcatgcact atggaaatgt tgctgagatg aatacggggg aaggtaagac
    20701 cttgacagct accatgcctg tctatttgaa cgctttttca ggagaaggag tgatggttgt
    20761 gactcctaat gagtatttat caaagcgtga tgccgaggaa atgggtcaag tttatcgttt
    20821 tctaggattg accattggtg taccatttac ggaagatcca aagaaggaga tgaaagctga
    20881 agaaaagaag cttatctatg cttcggatat catctacaca accaatagta atttaggttt
    20941 tgattatcta aatgataacc tagcctcgaa tgaagaaggt aagtttttac gaccgtttaa
    21001 ctatgtgatt attgatgaaa ttgatgatat cttgcttgat agtgcacaaa ctcctctgat
    21061 tattgcgggt tctcctcgtg ttcagtctaa ttactatgcg atcattgata cacttgtaac
    21121 aaccttggtc gaaggagagg attatatctt taaagaggag aaagaggagg tttggctcac
    21181 tactaagggg gccaagtctg ctgagaattt cctagggatt gataatttat acaaggaaga
    21241 gcatgcgtct tttgctcgtc atttggttta tgcgattcga gctcataagc tctttactaa
    21301 agataaggac tatatcattc gtggaaatga gatggtactg gttgataagg gaacagggcg
    21361 tctaatggaa atgactaaac ttcaaggagg tctccatcag gctattgaag ccaaggaaca
    21421 tgtcaaatta tctcctgaga cgcgggctat ggcctcgatc acctatcaga gtctttttaa
    21481 gatgtttaat aagatatctg gtatgacagg gacaggtaag gtcgcggaaa aagagtttat
    21541 tgaaacttac aatatgtctg tagtacgcat tccaaccaat cgtccgagac aacggattga
    21601 ctatccagat aatctatata tcactttacc tgaaaaagtg tatgcatcct tggagtacat
    21661 caagcaatac catgctaagg gaaatccctt actcgttttt gtaggctcag ttgaaatgtc
    21721 tcaactctat tcgtctctct tgtttcgtga agggattgcc cataatgtcc taaatgctaa
    21781 taatgcggcg cgtgaggctc agattatctc cgagtcaggt cagatggggg ctgtgacagt
    21841 ggctacctct atggcaggac gtggtacgga tatcaagctt ggtaaaggag tcgcagagct
    21901 tgggggcttg attgttattg ggactgagcg gatggaaagt cagcggatcg acctacaaat
    21961 tcgtggccgt tctggtcgtc agggagatcc tggtatgagt aaattttttg tatccttaga
    22021 ggatgatgtt atcaagaaat ttggtccatc ttgggtgcat aaaaagtaca aagactatca
    22081 ggttcaagat atgactcaac cggaagtatt gaaaggtcgt aaataccgga aactagtcga
    22141 aaaggctcag catgccagtg atagtgctgg ccgttcggca cgtcgtcaga ctctagaata
    22201 tgctgaaagt atgaatattc aacgggatat agtctataaa gagagaaatc gtctaataga
    22261 tggttctcgt gacttagagg atgttgttgt ggatatcatt gagagatata cagaagaggt
    22321 agcggctgat cactatgcta gtcgtgaatt attgtttcac tttattgtga ccaatattag
    22381 ttttcatgtt aaagaggttc cagattatat agatgtaact gacaaaactg cagttcgtag
    22441 ctttatgaag caggtgattg ataaagaact ttctgaaaag aaagaattac ttaatcaaca
    22501 tgacttatat gaacagtttt tacgactttc actgcttaaa gccattgatg acaactgggt
    22561 agagcaggta gactatctac aacagctatc catggctatc ggtggtcaat ctgctagtca
    22621 gaaaaatcca atcgtagagt actatcaaga agcctacgcg ggctttgaag ctatgaaaga
    22681 acaaatccgt gcggatatgg tgcgtaatct cctgatgggg ctggttgagg tcactccaaa
    22741 aggtgaaatc gtgactcatt ttccataaga ggagaaaata tgacaattta caatataaat
    22801 ttaggaattg gttgggctag tagcggtgtt gaatacgctc aagcctatcg tgctggtgtt
    22861 tttcggaaat taaatctgtc ctctaagttt atctttacag atatgatttt agccgataat
    22921 attcagcact taacagccaa tattggtttt gatgataatc aggttatctg gctttataat
    22981 catttcacag atatcaaaat tgcacctact agcgtgacag tggatgatgt cttggcttac
    23041 tttggtggtg aagaaagtca cagagaaaaa aatggcaagg ttttacgtgt attctttttt
    23101 gaccaagata agtttgtaac ctgttatttg gttgatgaga acaaggactt ggttcaacat
    23161 gccgagtatg tttttaaggg aaacctgatt cggaaggatt acttttctta tacgcgttat
    23221 tgtagcgagt attttgctcc caaggacaat gttgcagtct tataccaacg aactttttat
    23281 aatgaagacg ggactccagt ctatgatatc ttgatgaatc aagggaagga agaagtttat
    23341 catttcaagg ataagatttt ctatggaaag caagcttttg tgcgtgcctt tatgaaatct
    23401 ttgaatttga ataagtctga tttggtcatt ctcgataggg agacaggcat tggtcaggtt
    23461 gtgtttgagg aagcacagac agcacattta gcggtagttg ttcatgcgga gcattatagt
    23521 gaaaatgcta caaatgagga ctacatcctt tggaataact attatgacta tcagtttacc
    23581 aatgcagata aggttgactt ctttatcgtg tctactgata gacaaaatga agttctacaa
    23641 gagcaatttg ccaaatatac tcagcatcag ccaaagattg ttaccattcc tgtaggcagt
    23701 attgattcct tgacagattc aagtcaaggg cgcaaaccat tttcattgat tacggcttca
    23761 cgtcttgcca aagaaaagca cattgattgg cttgtgaaag ctgtgattga agctcataag
    23821 gagttaccgg aactaacctt tgatatctat ggtagtggtg gagaagattc tctgcttaga
    23881 gacattattg caaatcatca ggcagaggac tatatccaac tcaaggggca tgcggaactt
    23941 tcgcagattt atagccagta tgaggtctac ttaacggctt ctaccagcga aggatttggt
    24001 ctgaccttga tggaagctat tggttcaggt ctacctctaa ttggttttga tgtgccttat
    24061 ggtaatcaga cctttataga ggatgggcaa aatggttatt tgattccaag ttcatctgac
    24121 catgtagaag accaaatcaa gcaagcttat gccgctaaga tttgtcaatt gtatcaagaa
    24181 aatcgtttgg aagctatgcg tgcctattct taccaaattg cagaaggctt cttgaccaaa
    24241 gaaattttag aaaagtggaa gaaaacagta gaggaggtgc tccatgattg aactttatga
    24301 tcgttatagt catgaaagtc gagatttaca tgaaagtcta gtcgctactg gtctttctca
    24361 acttggagtg gtcatcgatg cagatggttt tctgcctgat ggtctgcttt ctccttttac
    24421 ctattatcta ggttacgagg atggaaaacc tctctatttt aaccaagttc ccgtttcaga
    24481 tttttgggaa attttaggag ataatcagtc tgcttgtatt gaagatgtga cgcaggagag
    24541 ggctgtcatt cattatgttg atggaatgca ggctcgcttg gttaaacagg tagactggaa
    24601 agacctagaa ggtcgagtac gtcaggttga ccactacaat cgctttggtg cttgctttgc
    24661 taaaaccact tatagcgcag atagcgagcc gattatgaca gtttaccaag atgtcaatgg
    24721 ccaacaagtt ttactggaaa accatgtggc gggtgatatc ttattgactt tgcctggtca
    24781 gtccatgcgt tactttgcaa ataaagttga atttatcacc ttctttttgc aagatttgga
    24841 aatagatacc agtcagctta tctttaatac tctagcgact cctttcttgg tttccttcca
    24901 tcatccagat aaatctggct cggatgtctt ggtatggcag gaacctctct atgatgccat
    24961 tccaggtaat atgcagttga ttttggaaag tgataatgtg cgtactaaga agatcatcat
    25021 tccaaataag gcgacttatg agcgcgcttt agagttaact gacgagaaat accatgatca
    25081 gtttgtgcac ttgggttatc attaccagtt caaacgtgat aatttcctaa gacgagatgc
    25141 cttaatcttg accaattcag atcagattga gcaagtagaa gcaatcgcag gagccttgcc
    25201 tgatgtcact ttccgtattg cagcggtgac agagatgtct tctaagctct tagacatgct
    25261 tcgctatcct aatgtggtcc tttaccagaa tgctagtcca cagaagattc aggagctgta
    25321 tcaactgtcg gatatttact tggatataaa ccacagtaat gagttactac aggcagtgcg
    25381 tcaggccttt gagcacaatc tcttgattct tggctttaat cagacggtgc acaatagact
    25441 ttatatcgct ccagaccatc tatttgaaag tagtgaagtt gctgctttgg ttgagaccat
    25501 taaattggcc ctttcagatg ttgatcaaat gcgtcaggca cttggcaaac aaggccaaca
    25561 tgcaaattat gttgacttgg tgagatatca ggaaaccatg caaactgttt taggaggcta
    25621 acatgtcaga ggaagattta ttttacaaag acgttgaagg ccgcatggaa gagttgaaac
    25681 aaaaacccat caagaaggaa aaagaaaccc gaggggaaaa gattagtaag actttttcac
    25741 ttttactggg tttgatgatt ctgattggtt tgctctttac tttgctggga attttgaggt
    25801 agatctatga ttgaaatact aattgtttta gctattatcc tatctcttgc tttgattgta
    25861 ttggtaacta tacaaccccg tcaaaatcaa ctattttcca tggatgccac tagtaatatt
    25921 ggtaaaccaa gctactggca gagcaacacc ttggtcaagg tgctcacttt attggtgagt
    25981 ttggctttat ttgttctact attaaccttt atggtgatta cttataaata aaagaaaact
    26041 tcagatattc accttttgtg gattggtctg aagttttctt ttttatactc aatgaaaatc
    26101 aaagagcaaa ctaggaagct agccgcaggc tgctcaaaac accgttttga ggttgtagat
    26161 agaactgacg aagtcagctc aaaacactgt tttgaggttg tggatagaac tgacgaagtc
    26221 agtaacatat atacggcaag gtgaagctga cgtagtttga agagtattac tgtctatatt
    26281 tttggtaaaa atcaactttt acttggatga aggttttggc ttcacgtagg agttgaagaa
    26341 gggtggcgcg ggtttcaaat tcttctcttg tcttgggcag actgcggttc cggaagactt
    26401 ccagataacg ttcaatttca tctagcaaat cagaagcagg attggtctgg ctcagttgac
    26461 ctgcaatttt tgaaaagagt tgcgctaaga tcaggctttc actggcggca aggtgacaag
    26521 tgttaatctg ttgggccatg tttctcagga tacgactttg tcgttgtctc atctcaaagt
    26581 agtggatatg gtagtcggtc tggtgaaaga ggtggtcaga gtgatccaaa tagaccagtc
    26641 tgagggcttc tttcaaaagc gtgtctaatt ctgctaccag ctgtgctcgg ttgcgtccgt
    26701 ctcctctgga taaatagtat ttgaagcgct ggaggatatc ttttaacttt tcttccacca
    26761 gcgtgtggta gtgctggatt tcctcttctc gtgaaggcat atagagatta acaagcaagg
    26821 caaatcctgt accaatagca aagagaagga attcgttgac taggaggtct ggagaggttg
    26881 actcttgaac caagagatgg ctaaccaaaa ccgtgcttgg tgtgatgcca atttcccagc
    26941 ccatcttgta ggctaaagga acgtagaagg ccagatagag gccgagactc cagatatgaa
    27001 atccgctcaa gtgaaaagct agaacaccga tagccagagc tagaagcata gaaaaaagac
    27061 gattgcgagc cagttttaaa gtacttctac gcgtatcaga taggctcaag agagcgataa
    27121 ttccagccga aactgctgac gaaagattga gaaaataagc aagcaggcag gcaagacagg
    27181 tagctaagat gagcttggtc gtacgttggc taatagacat aagaatttcc taataagtta
    27241 gaataaaagc gtaaaagaca agacatgagc aggcttgcct tgatgagtta ttttttacgg
    27301 gttgctgcgt attcggcaac ggcggtaaag aggacatctg tagaagagtt aagggctgtt
    27361 tcacatgagt cttggatgac accaatcaca aaaccaaccc caacaacttg tatggcaata
    27421 tcgttagaaa taccgaaaag gctacaagca actgggataa gaaggaggga acctccggca
    27481 atacctgaag caccacaggc tgagatagct gctaccacac tgaggacaaa ggctgtggca
    27541 aagtcaacag gaattccaag agtgttaact gtaacaaggg tcaaaacgtt aatggtaatc
    27601 gctactccag ccatattgat agtagaaccg agtgggatag aaacagaata ggtatctggg
    27661 ttgagtccaa ggtcatggca gagtttcatg ttgacaggaa tgttagtcgc agaactacga
    27721 gtgaaaaagg ctgtcacacc gctgacacgg aggcagttcc aaactagagg gtaaggattg
    27781 cgtctcatac tcataaagaa gaaggcaatc aaagggttga ccacaggggc aacaaaaagc
    27841 atagtcgtta ctaatggaac caataaaata ccgtagttgg caaggcttcc gactcccttg
    27901 tcagaaatgg ttttaaaaac aagaccaagg attccaaatg gagccagatt gatgatccat
    27961 tcgacaattt tagaagtcac gtcagcgata gtttttagca attctttact atttttactg
    28021 gcttctctca tagcgattcc aaaaatgact gcccaagata agattccaat atagttagca
    28081 gtaagcaggg cgttgactgg gttgtcaacc agtttgagca agaggttgct gaggacctgc
    28141 ccaatcccat ctggtggtgc aatttcagta ttggcactat ttagggtaat ttcaataggg
    28201 acgatgaaac ttgctagtac agctacaaga gcagcggcga aagtccctat cataggatat
    28261 acaagaaaac aacagttttc atattgctat cttgtccctt ttgatgttgg gaaagggcat
    28321 tggcaacgag agcaaagact aggataggag caacagcttt tagacctcca acgaataaat
    28381 cctcgagtag cccaatccct gagagattag gaagggtcag tcctaggatt ccccacaaag
    28441 cataccaatc aagatacgct tgacaaggct tgccttattc caagcatgaa tgattctttt
    28501 cataataatc tcctttttgt gtagtgatta tgattatagt ataaatgata gacaaaatca
    28561 agaattttct gtctattttt tgaatattta tggagaatga gactgatgaa aatatggtat
    28621 aatgaaataa aggagtttta tatgcaaaaa tttattcagg cttatattga aaagctagat
    28681 gtgacaacca ttatcgagaa tattctaacc aaggtcattt ctcttttact gcttttgatt
    28741 gtattttata ttgctaaaaa aatgcttcat accatggtgc agagaattgt caaaccttct
    28801 ctaaaaatgt ctcgtcatga tgtcggacgc caaaaaacca tctcacgttt actagaaaat
    28861 gtgtttaatt atacgctata tttcttttta ctctactgca ttttgtcgat tttaggtttg
    28921 ccagtttcta gtttgctggc tggagctggt attgctgggg tagcgattgg tatgggagcc
    28981 caaggctttc tgtctgatgt catcaatggc tttttcatcc tctttgaacg tcaactggat
    29041 gtgggagatg aggtcgttct gacaaatgga ccgattactg tatcgggtaa ggttgtcagt
    29101 gtgggaattc gtacgacaca gcttcgtagc gaggagcaag cccttcactt tgtccctaac
    29161 cgaaatatca cagttgttag caatttctca cgcacagact agacctgtta ttttaagtaa
    29221 tttgtggtac aatagaggga gtttaataag gagaaaagat ggttttagaa aagcagttgg
    29281 gcaatggttg tacctggata gacctagacc taggaaagtt gaataaacta gaagaccttt
    29341 ctgaaattta cggtttggac aaggaaacca ttgaatacgc actggataga aacgagcgcg
    29401 cccacatgga ctaccaccgt gaaagtggga cggttacctt tatctataat gtcctagatg
    29461 taaaaaagga caaggcctac tatgagactt ttcccatgac ctttattgtc gagcatcgtc
    29521 gcctgattac cattagtaat accaagaacg cctatgtcat tgaacagatg actcgttatc
    29581 tggagagcca tgacacgctt tcgatttata agtttctctt tgccagtctg gaaattatca
    29641 gcaatgccta ctatcctgtc attgagcaga tggacaagag tagggatgag gtcaatgacc
    29701 tcttgcgcca gcgaactacc aagaaaaacc tctttgtcct gtctgatttg gagactggta
    29761 tggtttatct gacggcagct gccaaacaaa atcggatttt gttagagcat attcaaggtc
    29821 atgccttgta tcgtagtttt gatgagattg agagagaaca gtttgatgat gccatgattg
    29881 aggctcatca gctggtatcc atgacagacc taatctctca gattttacag cagctttcag
    29941 cctcttacaa caatattcta aacaataatc tgaatgacaa tttgacaacc ttgactatca
    30001 tttcagtctt gctagctgtt ttggcagtcg tgacaggctt tttcggaatg aatgttccct
    30061 tacctttaac agatgagccc catgcttggc tctatatcag tttggctagt gcaggtttgt
    30121 ggattgtttt atccttgtta ctaaggaaaa ttgcgaaaaa aagttaagaa aaggagccag
    30181 aatggcgatt gaaaattata taccagattt tgctgtggaa gcagtctatg atctgacagt
    30241 cccaagcctg caggcgcagg gaatcaaggc tgttttggtc gatttggata ataccctcat
    30301 tgcttggaac aaccctgatg gaacgccaga gatgaagcaa tggctacatg accttcggga
    30361 cgcgggtatt ggcattatcg tagtgtcaaa taacaccaaa aaacgcgttc aacgagcagt
    30421 tgagaaattt gggattgatt acgtttactg ggccttgaag cccttcacat ttggtattga
    30481 ccgtgccatg aaggaattcc actatgacaa aaaggaagta gtcatggttg gcgaccagct
    30541 catgacagat atacgagcag cccaccgtgc agggattcgg tcaattttag tcaaaccctt
    30601 ggtccaacat gactcaatca aaacgcagat taaccgaact cgtgagcgtc gtgttatgag
    30661 aaaaatcact gaaaagtacg gaccgattac atataaaaaa ggaatttaac tatggaagaa
    30721 attctctgta ttggttgtgg agcaaccatt cagacgacag ataaagctgg tcttggtttt
    30781 accccccagt cggcacttga aaaaggtttg gagactggcg aagtctattg ccaacgctgt
    30841 ttccgtctcc gccactacaa tgaaatcaca gatgtccagt tgacgaacga tgatttcctc
    30901 aagctcttgc acgaggtggg agacagtgat gctttagtgg tcaatgtcat tgatatcttt
    30961 gattttaatg gatctgtcat cccaggttta ccacgtttcg tctcgggcaa tgatgtcctc
    31021 ttggtaggaa ataaaaaaga tatccttcct aagtcagtta agtctggtaa gattagccag
    31081 tggctcatga aacgtgccta tgaagaaggt cttcgtccag tcgatgtggt cctaacttca
    31141 gcacaaaata aacatgccat taaggaagtc attgacaaga ttgaacacta ccgtaagggc
    31201 cgcgatgtct atgtggtcgg tgtgaccaac gttggaaaat caactctaat caatgctatt
    31261 atccaagaaa tcacgggtga tcagaatgtc atcactactt cacgcttccc agggacaacc
    31321 ttggacaaaa tagagattcc gcttgacgac ggatcttata tttacgatac gccgggaatt
    31381 atccaccgcc accagatggc tcactacttg acggccaaaa acctcaagta tgtcagtcct
    31441 aaaaaggaaa tcaagcctaa gacctatcag cttaatcctg agcaaaccct atttttaggt
    31501 ggtttgggac gctttgactt tatagcagga gaaaagcaag gatttactgc tttctttgat
    31561 aatgaactca aactccatcg tagcaagctt gaaggagcta gtgctttcta cgataaacac
    31621 ctgggaactc ttctgacacc accaaatagc aaggaaaaag aagatttccc aaggctagtc
    31681 cagcatgtct ttaccattaa agataagaca gacctagtca tctcaggcct aggctggatt
    31741 cgtgtaacag gcacagcaaa agtcgccgtc tgggcaccag aaggcgtcgc cgtcgttaca
    31801 cgaaaagcaa ttatttaaaa caaaatcgct gagcgaacaa agtgagctca tatagcgata
    31861 gttattgccg tggtgtgatt gccaatctgt agattggcaa ggggcacaat tgagaccaag
    31921 gctcaattgt gaggtcagga aatccatttt tcaaagatga aatctttgga aaattagttc
    31981 cgaccgtccc tcaccaccta aaataactat caaaaaacaa ggaagaaaat tatgtcatta
    32041 acatcaaaac aacgtgcctt cctcaacagc caggcacaca ccctcaaacc tatcatccaa
    32101 atcgggaaaa atggactcaa cgaccaaatc aaaaccagcg tccgtcaagc tcttgatgcg
    32161 cgtgaattaa tcaaggttac tctcttacaa aacacagatg aaaacatcca cgaagtagct
    32221 gaaattttgg aagaagaaat cggtgtggat acagtccaaa aaataggacg catcttgatt
    32281 ttgtttaaac aatctagcaa gaaagaaaat cgcaagattt ctaagaaagt caaagaaatc
    32341 taagaccgaa actccaaata actgttttta tagagaaata aaggggacta gcctatgaca
    32401 atcgaactat tgactccctt taccaaggta gagttggagc cagaaatcaa ggagaaaaaa
    32461 cgcaaacaag ttgggatttt aggggggaat tttaaccctg ttcacaatgc ccatctcatt
    32521 gttgcggatc aagtacggca acagttggga ctggatcaag ttcttctcgt gcctgaatac
    32581 caacctcctc acgttgataa aaaggaaacc atccctgaac accatcgtct caagatgctt
    32641 gagttggcaa ttgaggggat tgacggccta gtcattgaaa ccattgagtt ggagcgcaag
    32701 ggtatttcct acacctacga caccatgaaa atcttgacag agcaacatcc agatacggat
    32761 tattacttta tcatcggcgc cgacatggtt gactatctgc ctaagtggta ccgaattgat
    32821 gaactggttg acatggttca gtttgtgggg gttcagcgtc cacgctacaa ggcagggact
    32881 tcctatccag ttatctgggt ggacgtaccg ctcatggata tctcgtccag catggtgcgg
    32941 gacttcattg cccaaggtcg gaaacccaac tttctcctac ctcagccagt gctagactac
    33001 atcgagaagg aggggctcta ctgatgtcct atcaagacta tatcaactgc tcccgtgagg
    33061 ccttgttgga aaaaatggca gagcttctac ctgagaaacg tctaacccat tgtctaggtg
    33121 tggagcgtgc cgctatggaa ttagctcagc gctttggtgt agatgttgag aaagcaagtc
    33181 tagcaggtct tcttcatgac tatgctaaaa agttgtcaga tcaggaattt ctagacttga
    33241 ttgaccgtta ccagctagac cctggcctca aaaactgggg caataatgtc tggcatggta
    33301 tggtcggaat ttacaaaatt caggaagatt tggatttgca tgattcagaa atcctgcgag
    33361 ccattgaagt ccatacagtc ggtgctggtc agatgacaga cctagataag gttgtctatg
    33421 tagcagacta tatcgagcac aatcgatcct ttcctggagt agatgtggcg cgtgaggttg
    33481 caagtctatc gctcaataag gcggtggcct acgaaacagc tcgtaccgtg gagtatctag
    33541 ctcatcaggg attccccatc tatccccaaa cccttgaaac ctataacgcc tttgtgcact
    33601 atttgaaaga gaactaaatg aagatggctt ttataatcat tgatgttcag aatgttttag
    33661 tagaaactgg gttccagaca aaaagtctat tggaaaaaat ttcttattta caaaaccagg
    33721 ctagaagcaa gaatattgaa attatctatg ttcaacatat tgagaactct gaagctcaaa
    33781 catcagaaga ttggcagtta tctgcgcttt taaatcgaaa acctgctgaa aaggtctttc
    33841 agaagaaata taacagtatt ttcaaagaaa ctggcttaaa agaatacttg gataagcagg
    33901 ggattgaaaa attagtttta tgtggtatgc agacagaata ttgtgtggat acctctgtca
    33961 agattgcctt tgaatatggc tatcagctta ttgttccaga aggtgctgtc acaacctttg
    34021 atggggatga cattccagca gaaacgatta atgaatttta tgaggacatt tgggaggagc
    34081 gctttgcaga tgtcctagat tacaaacata ttttctaaaa agaggattaa atgaacgaaa
    34141 aagaattact agaactagtc gtgaaagcgg ctgatgagaa acgtgcggag gatatcctcg
    34201 cacttgatgt acaagatttg actagtgtga cggactactt tgtcatcact agctcaatga
    34261 atagccgtca gctggacgct atcgcagcta atatccgtga aaaagtagct caagcaggct
    34321 ttaaaggtag ccatgtcgaa ggcgatgcag ctggaggctg ggtcttactg gacctcggtg
    34381 ctgttgtcgt gcatatcttt tcagaagaaa tgcgtgccca ttataatcta gagaagctat
    34441 ggcatgaggc gaattcagta gatatttcag aagctcttgc ttagaagatg aactcagttg
    34501 tagtcaactg ggtttctttg cttattttag aaaaattgat agaaaggtaa agggctagtg
    34561 gtgtttacca tggagctctt agtatcatga ttatggcgac ttatgaaacc tttgcggctg
    34621 tctatgatgc ggtcatggac gatagtttat acgacaaatg gacgaatttt tctctgcgtc
    34681 atttgcctaa gaccaaggag agaaagaaac tcttggaatt ggcttgtggg acaggaattc
    34741 aatcagtgcg cttctctcag gctggttttg atgtgactgg acttgacttg agtgcggata
    34801 tgttgaagat tgcggagaag agagcaactt cagccaagca aaagattgct tttatagaag
    34861 gtaatatgct aaatttgtcc aaggcaggga aatacgattt tgtcacgtgt tattcggact
    34921 ctatctgcta tatgcaggat gaggtggaag taggggacgt ctttaaggac gtgtacaatg
    34981 cgctgaatga agagggagtt ttcatctttg acgtgcactc gacctaccag acagatgaag
    35041 tattccctgg ctattcctac catgaaaatg cggaagattt tgccatgctt tgggatacat
    35101 atgaggacga agttcctcac tccatcgtgc atgagctgac tttctttatc aaggaggctg
    35161 acggttcctt tagtcgccac gatgaagtac atgaggagag gacctatgag atcttgacct
    35221 atgatatctt gctggaacag gctggattca agtccttcaa actctatgca gactttgagg
    35281 ataaggagcc aacagaaact agcacccgtt ggttttttgt ggcgcagaag taggagatta
    35341 gcatgaccat cacaggtatt atcgcggagt tcaatccttt tcataatggc cataaatacc
    35401 tgctggatca ggcagaggga ctgaaaattg ttgccatgtc agggaatttc atgcagcgtg
    35461 gagagcctgc tattgtggat aagtggacaa gggcccagat ggcgctggaa aatggcgcag
    35521 acttggtagt ggaattgccc tttttagtca gtgttcaggc agctgatttc tttggtcaag
    35581 gagctgtgga tatcttggat cgcttgggca ttgatagtct agtttttggg acagaggaag
    35641 ttcgagatta tcagaaaatc gctgacttat acacagagaa aggtgctgag atggagaaat
    35701 ttgtggaaaa tctgcctgat tccctttcct atccccagaa aacccaagct atgtggaagg
    35761 aatttgctgg tcttgatttt tcaggtaata cccccaatca tgttcttgct ctggcctatg
    35821 caaaggcggt tgcaggacga aatatcaagc tgcatccgat tcagcgtcag ggggcaggtt
    35881 accattctgt gaataaagat gtggactttg cctcggcgac agccctccgt caacatcaga
    35941 aggaccaaga tttcttagaa cgttttatgc cttctgttgc cctatttgag caggccagta
    36001 aggtgatctg ggaagactat tttcccttgc tccgctatca aatcttgtca aatcccgacc
    36061 taaccaccat ctatcaggtc aatcaagaaa tggctgtgcg cattaaagaa gctattaaaa
    36121 cagcccagtc tgtggaagaa ttggtcgagt tagtgaccac caaacgttac accaaggcgc
    36181 gtgtcagacg cctcttgacc tatatcttgg tgcaggctag agaaagtgac ttgccagaag
    36241 ggattcatgt ccttggcttt accgaaaaag gcaggcaaca tcttaaatat ctgaaagggc
    36301 aggtcagtct agtcagcaga attggcaagg aaccttggga tgtcatgact caaaaggcag
    36361 accagattta ccaattggga aatccaagta tagcagaaca gaattttggc agagtgccga
    36421 ttagaataga aacaaactaa gtctactgaa aggtaggctt ttttattgta gaaattttag
    36481 ctaacaaatt gaagataaag tttttggaaa atgataaact ccctaataca gaagacaaaa
    36541 agtcaataaa gaaaattagt atatgaacct taatctttat ctttgaatcc gctttatgct
    36601 tgttattttg tggtataatg aagagaactg gttatattaa aaatcataaa ttgaatataa
    36661 aagacaaata aatttttata tttataaacc atgataaact tttgtttaag attatgtaat
    36721 aaaaaagaag atttataaga ataatttgta tttatgtaat acaagctaat gataggatag
    36781 ttaaaatatg gaagaaaatt ataatttatc tataactcaa ataaagaatt ctattaaaga
    36841 aaattcctta gttttgtttg ttggtgcagg aatatcagct aattctaatc taccaacttg
    36901 gggagaattg attcaatcat taaaaaaaga attgaacata ccagaagaaa gaacagatag
    36961 tccactgaga attgctcagt attattatga tacttttggg aaaaatcagt acacaaagaa
    37021 gatagaagaa attttcttta agaagggatt gagtaaacca aatgagttac ataaattaat
    37081 agaaaaaatt gcaccaaaac atattattac gacaaactat gattcacttc tggagagtca
    37141 atttgaaagt ggcttgttaa agtacaatgt agtcgctgag gataaagaca tcccttatac
    37201 gagttcggaa agatacttga ttaaaatgca tggtgacttc agtaagaaaa atattgtttt
    37261 gaaagaagat gattatttag actatcattt gaacttccca atgatttcta ctttaatcca
    37321 gtcattgata atgaatcata ctctattgtt tgtggggtat tctctaagtg attcgacttt
    37381 taattcaatt tttagaatga ttcaaaatac atttaaattg gatgctaaaa atgcttattt
    37441 ttatactccc gaggaaccgt ctatgatcat tcgagagtat tataagaagc aaggaatttt
    37501 cattatctct aatgaagaga atctaggtca ggagacatca gaaaaacaga acaaattgta
    37561 ttgcaggaca aaagattttt tagaggttct atcagaaaac cgaagtcaag atgtaaataa
    37621 tgctgatgat ttatggaatc aactggcttt tttagataga cttagtttta ttgatgcgaa
    37681 agatttttct agatattctg atttaaagaa aagggcttta aactgggatg atgagtattg
    37741 ctggtttgga aatgatcaat taagatttga aattgatggt catgaagaat tacgaattat
    37801 ggtatctaaa aaatctttat taaatcgctt tctagatatg gagattggtg agcctaggga
    37861 tttaaagggg aatcgattct taagtaaggc ttttaagttg tatgaagaaa aacaatattc
    37921 tttagcaaaa gcaaaattta gagaactagc taatatagca tttcgtcaga aagactattt
    37981 taatttctta gtttgtgaat ttaattttca gcaaattcaa ataattgata gatacgaaaa
    38041 aacacctagt tatgcagagc cactttatga tggagaatta agtgaattaa cagaacaaat
    38101 tcttaactcg gttacaggag atgagaaaaa gattatagaa ttttttagag attcaatcct
    38161 taacttcaat tttttatata gaaaattaga aactattaat gaattatttg atgaaattcg
    38221 tgaagagcat gaaagctata gaagaggagg atggtctgct aataatcatc tatttaatgc
    38281 ggagtttaca gtaaaaaatc tttataactt tttaaaatta aattgtttat gtgttgaaca
    38341 ttataagatt tataaatcaa tcattaatag atatttagaa atattattac tcagttatga
    38401 taattcatat gtaaatcctg actcaagtat tttcgataga acatcttctt ggcttaaaaa
    38461 tcttgatttg gatgatgttc aattaattct tccgaatata gattttaagg ttgtaaattt
    38521 atattttaga aactattcat ttggtaaaat aaaagttact gaggaagcga aagactactt
    38581 gttgaatcga attacttatc ttcaagaaag acttgaaatt actgaagatg aaaatcttcg
    38641 agagcttaaa aatatgctaa tttttcttcc tcttgttgat gatattgaca tagaaaaagt
    38701 aatagaaatt ttaaataatc aaacactgta ttataattgg agagaggaat ttaggagaat
    38761 tattaaaatt gtcctcgata atatggatgt tattgataaa gattcattga aatctaagat
    38821 aattgggatt gtaaataaac atttaaatga aattttggag aaaaattttt ctttatataa
    38881 ttcagtgtat ccactctatt cacagttact agaatactgc tcaactgatc aggaaactgc
    38941 aataatagta ctcgaaaaat ttaatacaga tattttaaga ataaaatata aaaatgatga
    39001 tataaaaaat atcatagaat attctgactt gatatgccac ttatttaagt atttcgaaaa
    39061 ggatattaaa gatgacattc tagatactct aaaagtttat gaagaatcag aaaatattat
    39121 ttaccataaa gtaattgatt tgatgagtta taatgtctat gattttcctc agatacaaaa
    39181 taaaatctac cattatttga ttaaaagaat taatgataaa agagttgagg gggttaaaac
    39241 tttcccagac ccaagagaaa agtctgtatc agatttatac aacttaagta gaaaaggata
    39301 tttttctgat tttgagattt taaaagatat tgaagaagat attcgaggac tttatcctga
    39361 agtagattgg acctggttcc atgatagaag tgatgatgtt atccatcgtc tactagaaca
    39421 tagaactccc aataatatta aaacttattt ttcaaaaaat gaagaagata ataaattgat
    39481 taatgagtat attttaaaag ctttcgatga ggataaatta atacttaaga aataaattga
    39541 tacaactaaa taaaaaaagt taatttatga caaatttgat cttgaagata agctgtaatt
    39601 tcctaaagtg aattttcaaa gacttgaaag caaaatgttt gaatctagtg gaacactatt
    39661 tggcacaaca atagaaaatc catagttgta gaaattcggt ggaacttttt gatagcgaca
    39721 ctgacttatc tccttaaaaa accaaggaag tgtaatccta aaattcagac taaattcccc
    39781 aaaacatatt ctattttagg tttgtgaaaa tcactttttt atggtagaat gtaaaagaat
    39841 gtatgtcatt cggaataaca ataaaatgag gtaaaaacat ggaaatcatg tcgcttgcga
    39901 ttgctgtttt tgccgtcatc attggtttag tcattggata tgtcagcatc tcagctaaga
    39961 tgaaatcatc tcaggaagct gcggagttga tgcttttaaa tgctgaacaa gaagcaacta
    40021 atttacgtgg acaagctgag cgtgaagcgg atttacttgt taatgaagct aaacgtgaaa
    40081 gcaagtctct taaaaaagaa gcactattgg aggccaaaga agaagccaga aaataccgtg
    40141 aagaagtgga cgctgaattc aaatcagaac gtcaagaact caaacaaatc gaaagtcgtt
    40201 tgacagagag agctactagc cttgaccgta aggacgacaa tttgacgagt aaagaacaaa
    40261 cacttgaaca aaaagaacaa agtatttctg atagagcgaa aaaccttgat gcgcgtgaag
    40321 agcaattaga ggaagtcgaa agacaaaaag aagcagaact agagcgtatt ggtgctctgt
    40381 ctcaggcaga agcacgagat attatcttgg ctcagacaga ggaaaacttg accagggaga
    40441 ttgccagtcg cattcgcgaa gctgagcaag aggtcaagga acgttctgac aaaatggcca
    40501 aggacatctt ggttcaagct atgcaacgta tcgctggtga atatgtagcg gagtcaacaa
    40561 actcaacagt tcatctgcca gacgatacta tgaagggacg cattattggt cgtgaaggtc
    40621 gtaacattcg tacctttgaa agtttgacag gggtcgatgt gattatcgac gatacaccag
    40681 aagtggtgac cttgtcagga tttgatccga ttcgtcgtga gattgcccgt atgactatgg
    40741 aaatgttgct caaagatggt cgtatacatc cagctcgtat cgaagagttg gttgagaaaa
    40801 accgtcaaga gattgacaat aagattcgtg aatacggtga ggctgctgcc tatgaaattg
    40861 gtgcgccaaa ccttcatcca gacttgatga agattatggg acgtttgcag ttccgtactt
    40921 catatggaca aaatgttttg cgccattcga ttgaggttgc taagttggct ggtatcatgg
    40981 cgagcgaact tggtgaaaat gcggctcttg cccgtcgtgc tggattcctt cacgatatcg
    41041 ggaaagccat tgaccatgag gttgaaggta gccacgttga aatcggtatg gaattggccc
    41101 gtaagtacaa ggaaccccca gttgtggtga atacgattgc tagtcaccac ggagatgttg
    41161 aagctgagag cgtgatagca gttatcgtcg ctgcagcaga tgccttgagc gcagcccgtc
    41221 caggtgctcg tagtgagtct cttgaaagct acatcaagcg tctccatgat ttggaagaaa
    41281 ttgctaacgg ctttgaagga gtgcaaacta gctttgccct tcaagcagga cgtgaaattc
    41341 gtatcatggt caatccagga aaaatcaagg acgacaaagt cacaatcttg gctcacaaag
    41401 ttcgtaagaa aattgaaaac aatctcgatt atccaggaaa tatcaaggta accgtgattc
    41461 gcgagcttcg tgcagtagat tatgctaaat aaataagaaa gagcagttga aaaattactg
    41521 cttttttgtt acactagata gaaagactgt aaaggataat ctggcttttt gccattattc
    41581 tagagaaatg ttatttcaca gattgactaa aaggagacac aatggcagac cgaggcttac
    41641 taatcgtttt ttctggtcct tcaggggttg gaaaaggaac ggttagaaga gagatttttg
    41701 agagttctga aaaccaattt caatattctg tatcgatgac gacacgcgca caacgtcctg
    41761 gagaagtgga cggtgttgac tatttcttcc gtactcgtga agaatttgaa gagctgattc
    41821 gtcaaggaca gatgttggaa tacgcagaat atgtcggcaa ctactatgga actcctctga
    41881 cctatgtcaa tgaaaccttg gacaagggaa tcgatgtttt ccttgaaatt gaagttcagg
    41941 gtgctcttca ggtcaagaaa aaggttccag atgctgtctt tatcttcctg acaccaccag
    42001 atttggatga attgcaagat cgcttggtag gtcgtggaac agatagtgca gaagtgattg
    42061 cccaacgaat cgaaaaggcc aaggaagaaa ttgccctcat gcgtgagtat gattatgcga
    42121 ttgtcaacga tcaggtgccc ctagctgctg aacgtgtcaa atgtgtgatt gaagcagaac
    42181 acttctgtgt ggatcgtgtc attggtcact atcaggagat gttaccaaaa tctccaacta
    42241 cccgataaaa tttagaaaat aggtacaagc aaatgatgtt aaaaccctct attgatacct
    42301 tgctcgacaa ggttccttca aaatattcac tcgtaatctt ggaagcaaaa cgtgcccacg
    42361 aattggaagc aggtgcccca gcaactcaag gtttcaagtc tgaaaaatca actcttcgcg
    42421 ctttagaaga aatcgaatca ggaaacgtta caattcaccc agatccagaa ggaaaacgtg
    42481 aagcagtgcg tcgccgtatc gaagaagaaa aacgccgcaa agaagaagaa gaaaagaaaa
    42541 tcaaagagca aattgctaaa gaaaaagaag atggtgaaaa aatttaaggt tggggggact
    42601 caatcttatt ttttctattg caagaatgta ctgacaagga ggaggtgaga agatggccct
    42661 agctaagatt atcgtagatg tgcccttgat gcagacggac cagccctata gttacaggat
    42721 tccggaggaa tttgagggaa tgctggaagt tgggatgcgg gttcatgtgc cttttggtaa
    42781 gggtaatcgc ctgattcaag ggattgttct tggtttgaag tcccaatcag atggagaaga
    42841 gatggagcaa gatttaaaag atattgcaga ggtgctggat ttttctcctg ttctcacgcc
    42901 agaacaactc tggctggctg aggagttacg caaatctgtc ttctcctaca aaatctctat
    42961 cctcaaggcc atgcttccag ggtttctgaa ttctagctat gacaagattc tctatcctct
    43021 ggaaggcttg agtcaggaag aacgagtacg cctgtttggt tcagaagatt cgctagcctt
    43081 ttcttcacta gaccttgcca agcaagctga aatgatgcgt ttgactagaa aaggcctgct
    43141 tggtctggaa tatcaggcag tcgatcaaaa gaaggtcaag acccagtctt ggtatgaggt
    43201 tgaccatgcc caattagaag gtgttgagat ttctacacgt gccaagaaaa agttggaact
    43261 gagagattat ctgctgtctc atccagagag cgcttccttg gctagcttgt tagagtccta
    43321 ctcgcgagag caagtcaact tctttgtgga tcaaggtgct gttaccatag tccaaaagga
    43381 agttcaacgc tcggctgctt attttggagg aattgaagca agtagacctt tggagttaaa
    43441 tccagaacaa agacaggcgc gtgatgcggt tgtgagttct attggcagtt ctcaacctcc
    43501 ctttctactt caagggatta caggaagtgg gaagaccgag gtttacttgc agattatcca
    43561 aggtgccctg gataagggta agacagctat tttgctggta cctgagattt ccttgactcc
    43621 tcagatgacc gagcgtttta tagcacgttt tggggacaag gtagccattc ttcactcagg
    43681 attatccaat ggcgaaaagt atgatgaatg gcgcaaggtg gagcgtggcg atgcccaagt
    43741 tgttgttggt gccagatctg ctatctttgc tcctctgaaa aatctgggtg tcatgattat
    43801 tgatgaagag catgaagcgg cttataagca ggacagcaat ccccgttacc atgccagaga
    43861 ggtagctatt ttacgggctc agtataatca agcaactctg gtacttggat ctgcaacgcc
    43921 gagcttagag agccgggcac gtgctggcaa aggcgtctat caacacttac gtctaaccca
    43981 acgtgccaat cctttggcta caatccctga ggttcaagtg attgactttc gagactatat
    44041 cggacaaaat gagacgtcaa actttacgcc tcctttgcta gaggctatcc aagaccgtct
    44101 ggttaaaaaa gagcaggtgg ttctcatgct caatcgccgt ggttattcta gctttgtcat
    44161 gtgtcgggag tgtgggacgg tggatacttg tcccaactgc gatatttctc tgaccttgca
    44221 tatggatacc aagactatga actgccatta ttgtggtttc tcgaaggata ttcctcaggt
    44281 ctgtcctaac tgtaagagcc gcagtattcg ttactatggg acgggaactc agaaggctta
    44341 tgatgagcta gcagaactct ttccccaagc tcgcattttg aggatggatg tggatacgac
    44401 tcgaaagaaa ggcagtcacc aagccttgct tgaccagttt gggcgagggg aagcggatat
    44461 tttacttggt actcagatga ttgcaaaggg tttggatttt cccaatgtta ccctagtcgg
    44521 agttctaaat gcggatacgg ccttgaatct gcctgatttc cgttcttctg agagaacctt
    44581 ccagctcttg actcaggtgg caggtcgagc aggtcgggct gaaaaagcag gtcaagtctt
    44641 gatacagtcc tacaatccgc agcactatgc tattcgattt gccaaggatc aagattacga
    44701 aggcttttat gcctatgaaa tgggaatcag acgacaactc ggctatccac cttactattt
    44761 cacgattggt attacccttt ctcacaagaa agaagaagag gttttcaaac gtgcctatga
    44821 agtcatgaac attttgcggt caggcttgtc agagaccagt cccattctgg ggccaacgcc
    44881 aaaaccgatt gcccgtaccc acaacctcta tcattaccag attttaatta aataccgttt
    44941 agaagatgag ctggggccga ccctcaacca ggtcctggcc ttgactcaag aacgggaaaa
    45001 tagtgagctc cgtctcagta ttgaccatga gccgcagcaa tttttataag aaggagaaga
    45061 tatgacaaaa ctaatcttta tggggacccc cgacttttca gcaacagtct taaaaggact
    45121 tttgacagat gaccgttacg aaattctagc cgttgtgacc cagccagacc gtgctgttgg
    45181 tcgtaaaaaa gttatccaag aaaccccagt caagcaggct gccaaggaag caggactatc
    45241 tatctaccaa cctgaaaaat tatctggaag tccagagatg gaagatctta tgaagctagg
    45301 agcagatgga attgtgactg ctgcttttgg gcagtttctc ccaagcaaac tccttgatag
    45361 catggacttt gctgtcaacg ttcatgcctc cctccttcct agacaccgtg gtggtgcgcc
    45421 tatccattat gccttgattc aaggggatga ggaagctggt gtgaccatca tggaaatggt
    45481 taaggaaatg gatgcaggag atatgatttc tcgtcgcagc attccgatca cagatgagga
    45541 caatgttggc accttgtttg aaaaattggc gctagttggt cgtgatttgc ttttggacac
    45601 tctgcctgcc tatattgctg gtgatatcaa acctgaaccg caggatacga gtcaggttac
    45661 cttctctcca aatataaagc cagaggaaga aaaactggac tggaacaaaa ccaatcgtca
    45721 actctttaac caaattcgtg gaatgaaccc ctggcctgtt gcccatactt tccttaaggg
    45781 cgaccgcttt aagatttatg aagccctacc agtagaaggt cagggaaatc caggtgagat
    45841 tctctctatc ggcaagaaag aattgattgt cgcaacggct gaaggggctc tatccctcaa
    45901 acaagtgcag ccagctggta agcctaagat ggacattgct tccttcctca acggagttgg
    45961 acgtacattg actgtaggag aacgatttgg tgactaaagt agaaacggct agaagtttag
    46021 ctctagcagt gctagaggat gtttttgtga accaagcata ctcaaatatc gccttaaata
    46081 agcatctaaa gggaagtcaa cttttggcag cagacaaggg cttagtgacc gagctggtct
    46141 atggaacggt agcccgtaaa ctgactctgg aatggtacct atcccacttt atcgaagaca
    46201 gagaccagtt agacagctgg ctctatgtcc ttcttctcat gagtgcctac caactccgct
    46261 atttggacaa gattccagat catgctgtgg tcaatgaagc agtggaattg gccaaactcc
    46321 gtaaaaaagg cagtgaaaaa ttggtcaacg ctgtccttcg ccgtatcttg cgtgaaggct
    46381 ggccagatat tgctagcatc aagcgaaaaa acaagcgtga ctccattgcc tattctctcc
    46441 cagtttggct agttgccaaa ctcaaggaag aatacggaga ggagagagca aaagccatct
    46501 ttgaaagcct gttagtgcga aacaaagcca gtattcgtgt aacagaccta agtcgaaaag
    46561 aggaaatcca agccttgttg gaggcgaata attccctttt agcaaccact ggtctggtta
    46621 aggagcaggg gcattttgca gggcataatt tgtttgcgga tggagccatt accatccaag
    46681 acgagtccag tcagttggtt gctccgacgc ttgatttaca aggtgatgag cgagtgcttg
    46741 atgcctgtgc ggctccaggt gggaaaacag cccatatagc ctcttatctt acgacaggtc
    46801 aggttactgc tctggacttg tacgaccaca agttggattt aattcaagaa aatgcccaac
    46861 gtctgggagt tgcagatcgg gttcaaactc aaaaattgga tgccagaaag gtgcatgagt
    46921 tttttgacca ggattccttt gataagattt tggtggatgc tccttgttca ggaatcggtc
    46981 ttttgcgccg aaaaccagat atcaaataca ataaagaaac ggcagatttc gcgtccttgc
    47041 aggaaattca gttagaaata ttaggtagtg tttgtcaaat actaggcaaa ggtggtataa
    47101 taacttatag cacctgcact atcgtctcag aggagaattt tcaagtcgtt aaggcctttt
    47161 tagagagtca tcccgagttc gagcaggtaa aactagaaca tgaatgtaag gatatcatga
    47221 aagacggctg tatcctcatt acacctgaat tgtatggaag tgatggattc ttcatcagtc
    47281 aatttcgcaa gatatcggat taggaaggaa ctgacacatg gaaatttcat tattaacaga
    47341 tgttggtcag aaacgaacaa ataaccaaga ctatgtcaac cactatgtca atagagctgg
    47401 acgtaccatg attattttag ctgatgggat gggaggtcat cgtgcaggga atatcgctag
    47461 tgaaatggcg gtcacagacc tgggtgtagc ttgggttgat acccagatcg atacagtcaa
    47521 tgaagtgcgt gaatggttcg cccattacct agaaattgaa aatcaaaaga ttcaccagct
    47581 tggtcaggat gaagcttaca gaggcatggg aactactttg gaagtccttg ctattgttga
    47641 taatcaggct atctatgctc atattggtga ttcgcgtatc ggcttgattc gtggagaaga
    47701 ataccatcag ttgacgagcg atcattcctt ggttaatgaa ttgctcaagg ctggtcaatt
    47761 gacaccagaa gaggcagaag ctcatccgca aaaaaatatt atcacccagt ctattgggca
    47821 aaaagatgaa attcagcctg attttgggac agttatcctt gagtcaggtg actatctctt
    47881 gctcaatagt gacggcttga ccaacatgat ttcaggcagt gagattcgtg atattgtaac
    47941 cagtgatatt cctttagcag ataaaacgga gacacttgtt cgttttgcta acaatgcagg
    48001 aggtttagac aacattacgg ttgcccttgt ttctatgaac gaggaggatg cagaatgatc
    48061 caaatcggca agatttttgc cggacgctat cggattgtca aacagattgg tcgaggaggc
    48121 atggcggatg tctacctagc caaagactta atcttagatg gggaagaagt ggcagtgaag
    48181 gttctgagga ccaactacca gacggacccg atagctgtag ctcgttttca gcgtgaagcg
    48241 agagctatgg cagatctaga ccatcctcat atcgttcgga taacagatat tggtgaggaa
    48301 gacggtcaac agtatcttgc aatggagtat gttgctggac tagacctcaa acgctatatc
    48361 aaggaacatt atcctctttc taatgaagaa gcagtccgta tcatgggaca aattctcttg
    48421 gctatgcgct tggcccatac tcgaggaatt gttcacaggg acttgaaacc tcaaaatatc
    48481 cttttgacac cagatgggac tgccaaggtc acagactttg ggattgctgt agcctttgca
    48541 gagacaagtc tgacccagac taactcgatg ttgggctcag ttcattactt gtcaccagag
    48601 caggcgcgtg gttcgaaggc gactgtgcag agtgatatct atgccatggg gattattttc
    48661 tatgagatgt tgacaggcca tatcccttat gacggggata gcgcggtgac cattgccctc
    48721 cagcatttcc agaaacccct gccgtccgtt attgcagaaa atccatctgt acctcaggct
    48781 ttagaaaatg ttattatcaa ggcgactgct aaaaagttga ccaatcgcta ccgctcggtt
    48841 tcagagatgt atgtggactt gtctagtagc ttgtcctaca atcgtagaaa tgaaagtaag
    48901 ttaatctttg atgaaacgag caaggcagat accaagacct tgccgaaggt ttctcagagt
    48961 accttgacat ctattcctaa ggctcaagcg cagacagaac acaaatcaat caaaaaccca
    49021 agccaggctg tgacagagga aacttaccaa ccacaagcac cgaaaaaaca tagatttaag
    49081 atgcgttacc tgattttgtt gggcagcctt gtattggtgg cagcttctct tatttggata
    49141 ctatccagaa ctcctgcaac cattgccatt ccagatgtgg caggtcagac agttgcagag
    49201 gccaaggcaa cgctcaaaaa agccaatttt gagattggtg aggagaagac agaggctagt
    49261 gaaaaggtgg aagaagggcg gattatccgt acagatcctg gcgctggaac tggtcgaaaa
    49321 gaaggaacga aaatcaatct ggttgtctca tcaggcaaac aatccttcca aattagtaat
    49381 tatgtcggcc ggaaatcttc tgatgttatc gcggaattaa aagagaaaaa agttccagat
    49441 aatttgatta aaattgagga agaagagtcg aatgagagtg aggctggaac ggtcttgaag
    49501 caaagtctac cagaaggtac gacctatgac ttgagcaagg caactcaaat tgttttgaca
    49561 gtagctaaaa aagctacgac gattcaatta gggaactata ttggacggaa ctctacagaa
    49621 gtaatctcag aactcaagca gaagaaggtt cctgagaatt tgattaagat agaggaagaa
    49681 gagtccagcg aaagcgaacc aggaacgatt atgaaacaaa gtccaggtgc cggaacgact
    49741 tatgatgtga gtaaacctac tcaaattgtc ttgacagtag ctaaaaaagt tacaagtgtt
    49801 gccatgccga gttacattgg ttccagcttg gagtttacta agaacaattt gattcaaatt
    49861 gttgggatta aggaagctaa tatagaagtt gtagaagtga cgacagcgcc tgcaggtagt
    49921 gtagaaggca tggttgttga acaaagtcct agagcaggtg aaaaggtaga cctaaataag
    49981 actagagtca agatttcaat ctacaaacct aaaacaactt cagctactcc ttaaaagcag
    50041 atggataatc aaaatgagta atcaatcttt gtcatgattt catggcaaag attttttttg
    50101 agtccagatt tgtgatagaa tagagggagt tgataaaagg aggaaagcat ggaagaatca
    50161 aaagaattaa atgccgtcat tgatgtgatt atgctagcgg ggactattct ccttaaaagt
    50221 ggctcagaaa tccatcgtgt agaagatacc atgattcgaa tcgcgcattc gcaggggatt
    50281 gtggattgca atgtccttgc catgcctgcc gctatctttt tctctattga aaataccaat
    50341 atttcgcgca tgaagcgcgt gacctcctct tcttataaca tcgaaaaagt ctgcgatgtg
    50401 aaccagattt ctcgtcagct agttgggggg cagattgact tagaaacagc ctttaagcaa
    50461 ttgacggcct tgcaagctca accccttccc tatactaagt tgcaggtaac tctggctgcg
    50521 acctttagtg ctcctttctt ttcagttatg tttagcggaa atatctacga cgcacttggg
    50581 gcaggagtgg cgaccttatt tggttttgcc ttttccctct atgtggaaaa atttatccga
    50641 attccctttg tgacagcctt tgctggagcc tttgtctttg ggataattgc ccagttttgg
    50701 gctcgctaca caggttttcc ttcaacggca gatttgatta tagctggtgc ggtcatgccg
    50761 tttgtaccag gcattgcctt gaccaatgcg gtccgtgata ttatgaccaa ccacataaac
    50821 tctggtatga gtaagatgtt tgaatccctg ctcattaccc tcgctttagg ggcaggaact
    50881 tctgtcgcct tggtattgat gaactaatat gacactaaca acctttttat tacaagcagt
    50941 agcaagtttt cttgccatta tcactttttt aatcgtactc aatgtgcaac ggtctatgct
    51001 cttacctgga gggattttgg gcatgactgt ctggctaatc tatctcttgc tcaaggaacc
    51061 gaccaatgtc attgtagcta ccttcattgc agccattatt ggttcttgtg tcagccagat
    51121 tttaagtatt ctttataaga cacctgctgt ggtctttatc ttggccattt tggcaccgct
    51181 ggttccaggt tatctctcct accgaacaac tgcctttttt gtgacagggg actataataa
    51241 agcactggca agtgcgacct tggttgtcat gttggctctg gtaatctcta ttggaatggc
    51301 tagcggaaca gtgattctca gactgtatca ttatataaaa acacatcgag tatcgtagac
    51361 tttacagaaa taaaagaatt ttctgaaaaa tgagataaat aaattaacaa cgctttctat
    51421 atgtgcgaga ataccgcact tatgaagaaa ttacggctga ttttggtatc cacgaaagca
    51481 acttaatccg tcggagccaa tgggttgaag taactcttgt tcaaagtggt gttacgattt
    51541 caaaaactca tcttagtgct gagaatacgg tgattgtgga tgcaacagag gtaaaaataa
    51601 atcgtcctaa aaaaatcaac tagccaatta ttctggtaaa atagaaatgt cattctatgg
    51661 aacctcaagc gattgtcaca agtcaaggga gaattgtttc tttggatatc gctgtgaact
    51721 attgtcatga tatgaagttg ttcaaaatga gtcgcagaaa tatcggacaa gctggtaaaa
    51781 tcttggttga cagtggttat caagggctca tgaagatata tcctcaagca caaactccac
    51841 gtaaatccag caaactcaag ccgctaacag ctgaagataa agcctgtaac catgcgctat
    51901 ctaaggagag aagcaaggtt gagaacatct ttgccaaagt aaaaacgttt aaaatgattt
    51961 caacaaccta tcgaaatcat cgtaaacgct tcggattacg aatgaatttg attgttggta
    52021 ttatcaatca tgaactagga ttctagtttt gcaggaagtc tactattttc cttattgtct
    52081 gtaagtctac tgaccttgtt gtttatccca gtcatggttt ctagttcggg ctcagagttt
    52141 caaagtggat ggcaagagca tcaattgatt gctgagaagg ttagtaaaac acttgacaag
    52201 acatttgata aggatgtcag agaaattccg accagtcagt tttatcaaaa atttgtagat
    52261 gagatgggaa ggacttactc aggaaatttg atcctccagg agctgataac tgtgaatgga
    52321 gcttataaag ctacttatat cgatgaactc tctagcaact aatcattctt taaaatgatg
    52381 accaataaga ggcttgattt ggtgaatcaa gtcttttttc tctcttttac tgccatttgt
    52441 gataaaatag tatagaacga ttttttacat gaatgataaa acagaggtaa atatgacaat
    52501 cggtattgat aagattggtt ttgcgaccag tcaatatgtc ttgaaattac aagacttagc
    52561 agaagcgagg ggaattgacc ctgaaaaatt aagtaaagga ctcttactca aggaattgag
    52621 tattgcgccc ctaactgagg acatcgtgac cttggcggcc agtgctagtg actctatttt
    52681 aactgagcaa gaaagacaag aagttgacat ggtcattgtg gctaccgagt caggaattga
    52741 ccagagtaag gctgcggccg tctttgtgca tggcttgctg ggcatccagc cctttgctcg
    52801 tagtttcgag attaaagaag cctgctatgg ggcgacagct gccctccatt atgccaaatt
    52861 gcatgtggaa aattctccgg agtccaaggt attggtcatt gccagtgata ttgccaaata
    52921 tggtattgaa actccgggag aaccaactca aggtgctgga agtgtagcta tgttgattac
    52981 acaaaatcca cgcatgatgg cctttaataa tgacaatgta gctcagaccc gtgacatcat
    53041 ggatttctgg cgaccaaatt actcgacaac tccttatgta aatggtgttt attctaccca
    53101 acaatacttg gatagtttga aaacgacttg gcttgaatat caaaaacgct accagcttac
    53161 tctggatgat tttgcggctg tttgtttcca cttgccttat cctaaattag cgctaaaagg
    53221 cttgaaaaaa atcatggata agagcctgcc tcaagagaaa aaagacctct tacaaaagca
    53281 ttttgaccag tctattctct acagtcaaaa ggtggggaat atctacacag gttcactttt
    53341 ccttggactt ttgtctctct tggaaaatac agatagcttg aaagctgggg ataaaatcgc
    53401 cctttatagt tacggaagtg gagctgtggc tgagttcttc agtggtgaat tggttgaagg
    53461 atatgaagct tatttggata aagaccgctt gaacaagctc aaccaacgaa ctgccctatc
    53521 cgttgcagac tatgaaaagg tcttttttga ggaagtaaac ttggatgaaa caaaatctgc
    53581 ccagtttgct ggctatgaaa atcaagattt tgccttggtt gaaattcttg accaccaacg
    53641 ccgttatagc aaggttgaaa aataatgaag ataagttgga atggattttc taaaaaatca
    53701 taccaagagc gcctcgagct gctaaaagct caggcgctcc ttagtcctga gagacaagct
    53761 agtctggaga aggatgaaca gatgagtgtg actgtggcag accagctgag tgagaatgtg
    53821 gtgggaactt tttctctgcc ttattcgctg gttccggagg tacttgtcaa cggtcaggaa
    53881 tacaccgttc cctatgtgac agaagaaccc tctgtggttg cggcggccag ctatgccagc
    53941 aaaatcatca agcgtgcagg tggttttact gcacaagtcc atcagcgcca gatgattggg
    54001 caggtagccc tttatcaagt tgctaatcct aaactagcgc aagagaagat tgccagcaag
    54061 aaagcggagc tcttggagct tgccaatcaa gcctatcctt ctatcgttaa acgtggaggt
    54121 ggggcgcgtg atctgcatgt cgagcagata aaaggcgaac cagactttct cgttgtttat
    54181 attcatgtcg atacccagga agccatgggt gccaatatgc tcaacaccat gctggaagcc
    54241 ttgaaaccag tcttagaaga actcagtcag ggacagagtc tcatgggaat cctgtccaac
    54301 tacgcgactg attctctggt gactgcaagc tgtcgcatcg cctttcgcta cttgagccgc
    54361 caaaaggatc aaggacgaga gattgcggag aaaattgcgt tggctagtca gtttgcgcag
    54421 gctgatcctt accgagctgc tactcataat aaaggaattt ttaatggtat tgatgcgatt
    54481 ttgattgcca ctggtaatga ctggcgtgcc atcgaagctg gggcccatgc ctttgccagt
    54541 cgagatggac gctatcaagg tcttagctgc tggacgctgg accttgaaag agaagaattg
    54601 gtcggtgaga tgaccctgcc catgcctgta gcgactaagg gtggctctat cggcctcaac
    54661 ccacgtgtag ctctcagtca tgatctacta ggaaatcctt ctgccagaga attagcccag
    54721 attatcgtgt ccatcggtct tgctcaaaat tttgcagccc tcaaagcctt ggtaagtacg
    54781 ggcatccagc aaggccacat gaaactacag gccaaatccc tagctctcct agctggggct
    54841 agtgaatctg aagttgctcc cctagtagag cgcctcatct cagataaaac ctttaaccta
    54901 gagacagccc agcgctatct cgaaaattta agatcataaa aactcagacg aatcggtctg
    54961 agttttcttg tgtttaaata ctttttcctg gtaatagcgt aactggtaag aagtaaccag
    55021 ttgtggcgac ttccttgcct tcaatctttt gcaagagaag atcaatagtg agacaagcaa
    55081 tctcttccaa aggttgcttg atagtagcca attgagggta gtaattttcg ataaagtagg
    55141 tcccatcata gccgatgacc ttgagctctt ttgggacaga aatgcccaat tcttgagcga
    55201 ttttaatgac cagaatagct gtcaaatcat ccgaagcaaa aatggcatct ggtttttccc
    55261 gggtcaagat attcttgatt tccatttctt ttctgacggg agaaaagtca ctggaaacat
    55321 tgataatagg agcttttggg agtacggatg caaaaccagc gtggcgcagt ccggttggcg
    55381 aattggaatt gtcattccct gtaatcatga tgatagactg ggcacctgtc ttgaccaagg
    55441 tttgggcagc aagaacccca ccagcatagt tgtcagagga gacaacaggg atgtctggag
    55501 ataggtttcg gtcaaaggaa ataatcggcg ctgtcacacg attgtagtct tcgattccta
    55561 ggttgtgact accagaaatg atgccgtcta cctgattggc ttccaacatt tcgatgtatt
    55621 cgcgttcctt ctcagaatca tgttcactgt tgcagatgat ggtcttgtaa ccatttttga
    55681 agagttggtg ttccaattta tcaatcaatt ctgcatagaa aacattggaa atattgggga
    55741 aaatcaagcc gattaactta gctgattttc cttgcagact acgagccagg ttgttgggtt
    55801 tatagcctaa ttctctcatg gcttcattga ctttttggat ggttttctca gatagatatc
    55861 cttttttatt gataacccga gaaacggtag taggactgac gcctgcaagt ttggcgacat
    55921 cagttagttt tgcgaccata atctaattca tagtaagttc cagttgggtt tccagatttg
    55981 atcaggatac cattttggtc cgcatgtggg aagacacgac cagaaaatac tttttctcct
    56041 ttattgatga aaatttcaaa gacagagtta tcgatgaaga ttgtagcagt agtagcctga
    56101 ttctcgatag ggcaagaacg agttgtccca aattcttggg catactgttc tccagcctgg
    56161 ctacgatcca ctgtcacttg accgtttaca aggtcaaagt tgattgaaag tcccttacct
    56221 tctttatcag caagtaagac aatctcgctc tggctattag cttccaagtt gagttcaagt
    56281 tcgtaagtgt tcttggtttg ggaacggttt gagaaggctt cttcagaagc acgaaggtcc
    56341 ttaatagcag cgactggata ctggtagagc ttgtcgtctt tgatagtgag ttccttgacc
    56401 aaagagaagg ttccttggtg gtcaaaacgg tcagatgggt aagaaacatc tggcaaacca
    56461 agccagctaa ctgctagagc acgcccatca ggagcgttga aggcttgagt tgcataggct
    56521 tcgaaaccgt aatccatgtt ttgaagttga gacacatcta ccattttggc atttttaggg
    56581 tcaaaggaag ccccaatctt atacatattt ggaaagatat tatcgtagtc tagaactttc
    56641 ttatccaatc cttgtggaca gtagagaagg acaggatgtt cctctacaaa gaccagatta
    56701 ggacattcca tcatgtaggc agtacggtcg ttagcaaagt caaggtcgcc aactgcttgc
    56761 cagtttgtgt agtcgttatt gacagccttg tagagacgga cgaagccttt tttctccaag
    56821 tcctgtccac cgacgacagc atagtattga cctttaaagt taaaaatttg tggatcgcgg
    56881 aagtggtcag tagagtctgc tggctggtca atcaagatct tgtcaatctt tgtaatctta
    56941 ccctccttgt ccatcaaagc accgatctgg tatgggtgac ggatccagtt ttcatcgcga
    57001 acatttcctg tataaaatag gaataagtta tcgccaaatt gcatggcaga accagagtag
    57061 gcaccgtggc tatctaatgg agtatctggt aaaactttga ttccagtttc tttaaagtga
    57121 accaaatcat cactttctag ctgtgcccaa gatttcaaac cgtgggctgc accaaaagga
    57181 aaattctggt aaaagaggat ccacttgcca tcaaagtaag aaaagccatt tgggtcgttg
    57241 agaagtcctg tttttggctc aacatggtaa tgagtatgcc atggagattg tgccatattt
    57301 tcctttatat gttgaatttc ttcttgcgtc caatcttgat aaagtctgta acgacgctca
    57361 gttgtccatt ccattcattc ctccaaaaat cttatcactt ttaatagtaa ctgttttcga
    57421 taaaaaatgc aagcctttta tgttaaaaaa gaggaaaaac tgtcaaacga ttatcataaa
    57481 ataaatacag gaaatcaatc aaatttttac gaaaatgtga aagataatga aataaaagac
    57541 ttttcaacca aggtttcaaa cttatttttc aaggaattcc tgatgaaaca gtcaaaaaca
    57601 atcaatctaa aacttgccca ctaagtggat agaatatttt ttctgcaaaa cgcttgacat
    57661 atttttaaaa catgataaaa taatagtcgt aagggcgaat aaaatcgctt tcaaacaaga
    57721 acaaaatgtt atataaggag atttttgcta tggattatag taaagttgct gccgaggtca
    57781 ttggggctgt cggtaaggat aatcttgtag ctgcagctca ctgtgcgaca cgtcttcgct
    57841 tggtattgaa agacgaagca aaagtgaatc aagcagctct ggataataat gcggatgtca
    57901 aggggacttt tagcactaac ggacaatatc aaattatcat tggtcctggt gatgttaact
    57961 tcgtatatgc ggaaattatt aagaaaactg gtttgaaaga agtttcgaca gatgatttga
    58021 aagagattgc taataaagac aaaaagttca atccattgat ggacttgatt aaacttttgt
    58081 cagacatttt tgttcctatt atccctgcct tagttgcagg tggtctcttg atggctttac
    58141 ggaacttctt gacatcacca gatttgtttg gacctcaatc aattgaagat atgtatcctg
    58201 ctatcaaagg cttctcagct atgattcaat tgatgtctgc tgctccattt atgttcctcc
    58261 ctgttttggt tggtatttca gcagccaagc gctttggagc aaaccaattc cttggtgcgg
    58321 caatcggtat gattatgacc actccagatt tgggtggtaa agaagccttc tgggacatct
    58381 taggtttcca tgttacacaa acaaactatg cttatcaggt tattccagtc cttgttgcag
    58441 tctggttgtt agctaattta gaaaaattct tccacaagaa attgccatct gcagttgact
    58501 tcacttttac accgctttta tcagtgatga ttacaggatt ccttaccttt acagttatcg
    58561 gtcctgttat gttggttgtg tctgatgcga ttacaaatgc gattgtatgg ttgtacaaca
    58621 caacaggtgc ctttggtatg gggctatttg gtggaactta ctcattaatc gttatgacgg
    58681 gtcttcacca atcattccca gcaatcgaaa cacaattgtt gtctgcatac aataataacg
    58741 gtactggatt tggagactac atctttgttg ttgcttcaat ggcaaacgta gcacaaggtg
    58801 cggctactct tgcagtctac ttcttgacaa aaaatgctaa aacaaaagga ttgtccagtt
    58861 cggctgctgt ttctgccttc cttggtatta cagaacctgc tctctttggg gtaaacttga
    58921 aatacaaatt cccattcttc tgcgcccttg ctggttcagc aattggtgcc tttgtagcag
    58981 gtttaactca cgttattgca gtttcattgg gagcggctgg atttattgga ttcctttcta
    59041 ttaaggctgg ttcaatccct atgtatataa ttgcggaaat tatgtccttt gttgccgcct
    59101 ttgctttcac ttatttctac gggaaaacaa aagcagctag tgtctttgct gatgaagctg
    59161 ccacagcaac cgcagaaaca gttacagaac ctacagtaga agcaccagta gtggaagaga
    59221 ctgatactct tcaaaatgaa acacttgtaa ctcctatcgt tggtgatgtt gtcgctcttg
    59281 ctgatgtcaa tgacccagtc ttctcaagtg gagctatggg acaaggtatc gctgtgaaac
    59341 caagccaagg cgtggtctat gcaccagctg atgctgaagt ttcaattgcc tttccaacag
    59401 ggcacgcttt tggtttgaaa acaagaaatg gtgctgaagt tttgattcac gttggtattg
    59461 acactgtatc tatgaacggt gacggttttg aagcaaaagt tgctcaaggt gataaggtga
    59521 aagttggcga tgttcttgga acatttgact caaacaaaat cgctgcagct ggacttgatg
    59581 atacaacaat ggttatcgtt acaaatacag ctgactacgc ttcagtagct ccagtcgcaa
    59641 caggttcagt tgcgaagggg gatgctgtga tcgaagtgaa aatctaatca atcctctcta
    59701 atgtgaaaac gaacaaatga catgtttgtt cgtttttatt agatagtaag atttacagag
    59761 gaaaatctaa aaaatagaga catttagact ttcgaagtat gctataataa agaaaataaa
    59821 aacaagaggt ttatcatgac aaaattatat ggaagcttgg aagcgggcgg tacaaagttt
    59881 gtctgtgctg tcggtgatga aaactttaac gttgtagaaa aaacacaatt tccaacaaca
    59941 actccaatcg aaacaatcga taaaaccatt gagttcttct caaaattcga taaccttgct
    60001 ggtcttgcag ttggttcatt tgggccgatt gatattgaca aaaactcaaa aacttatggc
    60061 tttatcacga cgactccaaa accaaactgg gcaaatgtgg acttgcttgg tgcccttcgt
    60121 cgcgccctaa acgtgccaat gtacttcaca acagacgtaa acagctctgc ttacggtgaa
    60181 atggttgccc gtaacaatgc tggtggtcgt atcgaaaact tggtttacta cacaatcggt
    60241 acaggtatcg gtgcaggcgt catccaacgt ggtgagttta tcggtggtgt gggtcaccct
    60301 gaaatgggtc attattatgt tgctagacac ccaatggata ttgaaaaaga gtttaagggt
    60361 gtttgtcctt tccataaggg atgtctagaa ggttatgcag ctggtccaag tttggaagct
    60421 cgtacaggtg tacgtgggga aactattgaa ctcaacaacc ctgtttggga tgttcaagcc
    60481 tactatatcg ctcaagctgc ggttaatgcg acagtgactt tccgcccaga cgtgattgtc
    60541 tttggtggag gggtcatggc tcaacaacat atgctggacc gtgtccgtga gaaatttaca
    60601 tctcttctta atggttacct accagtacca gatgtgcgtg actatatcgt gacgccagca
    60661 gtcgcaggaa atggttctgc cacacttggg aactttgttc ttgcaaaaga agtttcaaaa
    60721 taaagcacaa aatccgcttg ggaaaccaaa cggattttgt ggttgaaaac aatatttttg
    60781 agcctttcct taagtgatta cggacggtag cgactttctt cgaaattcca tacctaaact
    60841 ttgagacact aggctcaaag tttccgaata cctgaaacca ttagatttca ggtgtttcta
    60901 tcacggcggg aaggctaggt aagtcctcgc ctcactatcg aaaaatatgc atgatttcca
    60961 taccaaagta tatttagtat caagctatag ttaatctacg ctttaaaaat ccacttggga
    61021 aaccaaacgg attttttacg tgtcaaagca tttgccagaa aaagtcaata atataggtca
    61081 gaccgtaggt ataaaccacg agggtaaagg gtttggtcag aatgatgata gtcatgtagc
    61141 gcttgaaact catcttggtc agggcagcca gcatacagag aaagtcagct gggctaatgg
    61201 gccaaatcat cataaaaata aagaagcggt caaaacgatt gcccttatct agccagccga
    61261 tgtacttgtc gtaggtgcgc ttgctgacga cagactggac aaaggcagct ccgtataggc
    61321 gcaccagata aaagataatg gcacagccaa tcacgatgcc gatatagttg tagatagtcc
    61381 cgatgatgtg cccgtagata aagaccccag ccaccgaggt caaggcccct ggaatgatag
    61441 ggacgacagt ctgtaaaatc tgtaaaaaga taaagagagg tggaccccag atgcctgcct
    61501 gctggataaa ggcagagagg gtttccttgg attgtaaaat cccagcctga taagcccaaa
    61561 tacagaaaat caaactccca accccaccga caatcgatga gatattgata actcgctgca
    61621 gaaggggaga aacagctttc atttgtttat cctgtgacat gtaaactcct catagatagt
    61681 atatttctac tataccatat tttggaggag aaagggggaa tgagtctttt ttgataagga
    61741 atagaaagta aatagccctt cgagacttag aataggtctg tcaactaaag gttatatgca
    61801 ttctaggttt cgaataatcg caattccata aatttaaaag cattctaagt ttcgaatagc
    61861 ttatctgaga taattttgag gcattcgcgc tttcgaatag tcattttccc taaagtttat
    61921 atgtatcctg aagccagaaa gactaaaata taaaagtagt aagagtctct ctctgatgga
    61981 cgtaatttat ggctagtatg aatcctttga attgttagtt aattttaata ttaatcagtt
    62041 ctgaaataat tactaaatat agttagatgg tgaattaatt attgctaaat ttcaagttca
    62101 agttagtcat ccagaagtct tctctggggg acttgtagtt caagcatttt ttaggatagt
    62161 tgttaatcca cttttcgatg aatgcgactt cctttgtagt cgttttctta gtttcctgag
    62221 gtaaccatct atgaatgagc ctgttgtgat tttcattaga tcctataggg gtgtgcataa
    62281 tagatatagc agattgaaac tagaatagta tacatctact tctaaaacat tgttagaaat
    62341 cgatttgact gtcccgatct atttgtcctg tttttatttc attttactat ataatcctta
    62401 gaaaatatat cggacaagcg gttgaattcc gttccgtcca ttagtagata aaggattact
    62461 ccttcttgaa atgacagatg aacttgtttc ttataaaaat gttgtctgaa actattcgct
    62521 tttttccaga agttttagag gaagaaaact ttatgaggaa aaaggagtta ctcaaataac
    62581 aattcaggat taaaaataga cagttgagga gcggaaggta taaattgagt ttgctactgt
    62641 ataatggatt tatcactaat actcttcgaa aatctcttca aaccacgtta gcttcgcctt
    62701 gccgtagata tagttactga cttcgtcagt tctatccaca acctcaaaac agtgttttga
    62761 gctgacttcg tcagttttat ctgcaacctc aaagctgtac tttgagcagc ctacggctag
    62821 cttcctagtt cgctctttgc ttttcattga gtataaaagt gctccaggcc atattttaca
    62881 cagcaatagt cttctaaaaa tggacaaaaa cattgtaaag gctatcaaaa aggagtataa
    62941 tgagtgcaag aaatttcgga ggtgaaagat gctagaagta agaagtctag agaaaagttt
    63001 tggctccaag caagttttgt ttggtattga ctttcaagcg cgaccaggtc gtattttggg
    63061 actagtcgga aaaaatggtg ctggaaaaac aacgattttc catagtattt tgaaattcct
    63121 agaatatcag ggagaaatcg gtctggatgg tcaggatatt cgtcaggaga cctatgctcg
    63181 gattggttat ctgcctgaag aacgcagtct catgcctaaa ttgacagttc ttgaacaagt
    63241 tcgctacttg gcgactctaa aaggcatgga tgccaaagaa gtcaaagaaa aactccctca
    63301 atggatgaag aggttggaag tgaaaggaaa gctgacagat aaaatcaaga gtctgtcaaa
    63361 aggaaatcag cagaagattc agctcattat tactctgatt catgaaccag acctgattat
    63421 cttggatgag ccttttagtg gattggaccc agttaataca gaattgctca aacaagtcat
    63481 ttttcaggaa aaagagcgcg gagcaaccat tatcttttct gaccatgtca tgaccaatgt
    63541 tgaggaactt tgtgacgata ttctgatgat ccgagatggc cgtgtggtct tgcacggacc
    63601 agttcaggat gtccgcaatc aatacgggaa aacgcgtctc tttgtttcaa gtgaacgaag
    63661 caaggaagaa ttggaaaatc ttcctcatgt caaacaggtg agcttgacca aacaaggcag
    63721 ttggaaattg attttggagg atgagagcgc tggaagggaa ctcttcccaa tcttgactca
    63781 aggtcaatat atcgcaacat ttgaccaaca agcgccaact atcgatgaaa tctttaaact
    63841 agaatcagga gtggaagtat gagaaatatg tgggttgtaa tcaaggaaac ctatcttcga
    63901 catgtcgagt catggagttt cttctttatg gtgatttcgc cgttcctctt tttaggaatc
    63961 tctgtaggaa ttgggcatat ccaaggttct tctatggcta aaaataataa agtggcagta
    64021 gtgacaacag tgccatctgt agcagaagga ctgaagaatg taaatggtgt taacttcgac
    64081 tataaagacg aagcaagtgc caaagaagca attaaagaag aaaaattaaa aggttatttg
    64141 accattgatc aagaagatag tgttctaaag gcagtttatc atggcgaaac atcgcttgaa
    64201 aatggaatta aatttgaggt tacaggtaca ctcaatgaac tgcaaaatca gcttaatcgt
    64261 tcaactgctt ccttgtctca agagcaggaa aaacgcttag cgcagacaat tcaattcaca
    64321 gaaaagattg atgaagccaa ggaaaataaa aagtttattc aaacaattgc agcaggtgcc
    64381 ttaggattct ttctttatat gattctgatt acctatgcgg gtgtaacagc tcaggaagtt
    64441 gccagtgaaa aaggcaccaa aattatggaa gtcgtttttt ctagcataag ggcaagtcac
    64501 tatttctatg cgcggatgat ggctctgttt ctagtgattt taacgcatat tgggatctat
    64561 gttgtaggtg gtctggctgc cgttttgctc tttaaagatt tgccattctt ggctcagtct
    64621 ggtattttgg atcacttggg agatgctatc tcactgaata ccttgctctt tattttgatc
    64681 agtcttttca tgtacgtagt cttggcagcc ttcctaggat ctatggtttc tcgtcctgag
    64741 gactcaggga aagccttgtc gcctttgatg attttgatta tgggtggttt ttttggagtg
    64801 acagctctag gtgcagctgg tgacaatctc ctcttgaaga ttggttctta tattcccttt
    64861 atttcgacct tctttatgcc gtttcgaacg attaatggct atgcgggggg agcagaagca
    64921 tggatttcac ttgctattac agtgattttt gcggtggtag caacaggatt tatcggacgc
    64981 atgtatgcta gtctcgttct tcaaacggat gatttaggga tttggaaaac ctttaaacgt
    65041 gccttatctt ataaatagaa gagccttgcg aaagcgaggt ttttaaaggt gaaaagggtg
    65101 gaatcacgaa cctaattatg tacacattat gtaaacaggt tgcttgaaaa ctcaattgta
    65161 tagtgaactg aatctggaat aggataatat tacttctaaa acattcttat aaattgattt
    65221 gaattccaaa atcccatcgt tccgttctta tttcattttg cgatatagcg aaaggaaata
    65281 agtcagctca caaaaaacgc ataatatcaa ggatttttaa cacttgatac tatgcgtttt
    65341 ctaattttaa agactttttg cctggtctct tttgttctat gagtatgtta catatctagg
    65401 taaaaattat ttaaagcaaa ttaaccttat ttctcaagat gtagtaggtt ccgagataaa
    65461 agatagctat gaatatgagt tctttaacaa tggctatacc tgctcccata tagaaatggt
    65521 cattgagtcc taccagtgaa ttgacataga aattggaact aagattgaag aaaagttcaa
    65581 taaatccaat gacgatttgg ataccaatgt aggctgcaac agcgagtgct gtacggtatt
    65641 cattgaaaag ctgtccaatg gaaatagcca ggtagatgca gaggattcct gaaatggtat
    65701 ttagtaggaa ggatatacct gtaagaaaga tctgagggag atgtgtttct acaaatgtaa
    65761 tcacataaga aagaggaatc cattctggag ctgttaaagc cagaataata acagcactta
    65821 gagccaatac agcggtgcta atcaatgacc agataaaggc accgattagt ttggctgtga
    65881 tgatatggtg ttcagaaact ggcaaggtca aagtcagata gccttgtcgg tcgtagacac
    65941 tacctttgaa gcgtttaata atcaagaaaa tggttgaaat cgcaagtgta agcatcaagc
    66001 caccaaagac tgtagctaga aaaagtagca tagtagcctg actttcttgg taaggtagat
    66061 ttttaaagcc ttgtgtctgt attccgatga gggcagaaag gactagcacg gctgcgtaga
    66121 gggctaaata ccacttgtta acatttttaa attcgtagtg aactaaattc caaaacataa
    66181 ataatctcct ttgcttaggc cttaaattcc tgacggaaga gttggtcaat ggattcacct
    66241 gactcgtagc gaatatcatc tacatttcct tgacggacga cttttccgtc ttttaggaag
    66301 acaatttcat ccaagattgg ctcgatatca gaaatcaagt gggtagaaat caaaacggta
    66361 gaagttggtg agtagttgtt gataatggta ttgaggatat aagcacgggc tgctggatcc
    66421 accccaccaa tgggttcatc caaaacatag agacgagcat cacggctcat aaccaaaatc
    66481 agttgaacct tttctttgtt tccttttgat agtttcttga gacgactatt ttcatcaatg
    66541 cccaggtctg caagtagatg atgggcgcgt tcaagattga aatctttata gaaggtcttg
    66601 aagtaggtta gggcttcttt gaccttcatt tgctcattga gataggtcgt atcaggcaaa
    66661 taagctacaa cggccttggt tgctgggctt gggtccatgt cgttgatgag gacacgtcct
    66721 tgatctggtt gtaagaggcc attaattagt ttaatcaggg ttgtttttcc tgagccgttt
    66781 ggcccaagaa ggccgacaat ttttccagct ggaatgtcaa gagaaacatt ttcaagggct
    66841 ggtgttgctc catatgattt ggatacattt tcaaatgcta gtaatgacat aggcttaaac
    66901 tcctttaata taatcactga ctacgcctgg tagttcttct ttttcatagc caaaatgggt
    66961 catggaggaa acgaagtgtt ccaattcttc ttctgataat tgtttgcgtg actgagcgat
    67021 tagctcctta tccttagtca caaatcgtcc agttgttcgc ttgctgtaga caaatccttc
    67081 tcgttcaagg tctgataagg ctctttggat ggtattggga ttgacaccag cctcactagc
    67141 tagctccctc acggttggaa gttgttgatt gggttccagt gtatgggaaa caatctgaag
    67201 cttgattttc tccataatct gtaaatagat gggttttttg ttgtcaaatg tccaggacat
    67261 cttagtctcc tttctcttac ccttttgtct taattaaata atacaacaaa acaaaaaact
    67321 tgtcaagcaa aaagaagaat tgttttggga atcgcttaaa aaatggtata atgaaaagaa
    67381 aacgataagg agggaaagga tgcgttgtcc aaaatgtggg gctaccaagt caagtgttat
    67441 cgatagtcgc caagcagaag aagggaacac cattcgtaga agacgagagt gcgacgagtg
    67501 ccaacaccgt tttacaacct acgaacgagt agaagaaaga accttagtgg ttgttaaaaa
    67561 agatggcaca cgggaacaat tctccagaga taaaatcttt aatgggatta tccgctcagc
    67621 ccagaaacgt cctgtgtcaa gtgatgaaat caacatggta gtcaatcgta tcgaacagaa
    67681 actccgtggt cgaaatgaaa atgaaattca aagtgaggac attggttcac tcgtcatgga
    67741 ggagttggct gaattggacg agattaccta tgtacgtttt gctagtgtct atcgtagttt
    67801 taaggatgtc agtgagttag agagcttgct ccaacaaatc acccagtcct ctaaaaagaa
    67861 aaaggaaaga taaatgaagc caattgaccg tttttcttat ctaaagaata atcgggtgtc
    67921 gcaagatacc tcatctctgg tacagtgcta cctcccgatt atcggtcagg aggcactgag
    67981 cctttatctt tatacaatca gtttttggga taatggtaga aaggaatatc ttttttcaag
    68041 tatcctcaat catctcaact ttgggatgga tagactgata aaatcattga aaatcttatc
    68101 tgcttttaat ctcttgaccc tctatcaaaa gggggatgtt tatcagctag ccctccatgc
    68161 tcctctatct agtcaagact tcttggagta tcctgtttat cgcagactct tagagaaaaa
    68221 gattggcgac tctgctgtgg aggatttgaa agttgaaagt gctgatggtg aagaaatacc
    68281 tgtctcactc aatcaagtct ttccagaatt ggcagaacta ggcagtcaag aagaccttgg
    68341 tctcaagaag aaagtggcca atgattttga cttggaacat tttcgccagc tgatggctcg
    68401 agatggactt cgttttgcgg atgagcagtc cgatgtctta aacctctttg ctattgccga
    68461 ggagaagaaa tggacttggt ttgaaaccta tcaattggcc aagtcaacag ctgtttctca
    68521 ggttatttca accaaacgca tgcgtgaaaa aattgctcaa aaaccagttt cctctgactt
    68581 tagtcttaag gaaacaacca ttatcaaaga agccaaaagt aaaactgccc tgcagttctt
    68641 ggcagaaatc aagcaaacac gcaagggaac cattacccaa acagaaagag aactcttgca
    68701 acagatggct ggcttgggct tgctggacga agtcatcaat atcattcttt tattgacctt
    68761 taataaggtc gattcggcaa atatcaatga gaaatatgcc atgaaggtag ccaatgacta
    68821 tgcctatcaa aagattcatt cggcagaaaa ggcagtcttg cgcatccgtg agcgaggaca
    68881 gaaagcaaaa acacaaaaac agaatcagac tgccccagta aaaaccaatg ttcctaaatg
    68941 gagtaatcct gaatataaga atgaaaccag cgaggaaact cgtctggaac tagaacgtaa
    69001 gaagcaagaa ctattagctc gattagaaaa aggaggagat tagatggaaa gtgtcggaga
    69061 cgtactcaaa cgtcaaccca gccgttttta ttatcaagat ttggtccaga aaatcatgaa
    69121 ggaccctgat gttgcggctt ttatccagca agaatccttg actccagagg aattaaatcg
    69181 cagtatctcc aagtttaatc agtacatcac cgagcgtgac aagtttctcc gtggggatac
    69241 ggattatatt gccaaaggct acaagccgat tttggttaag aatcatggct atgcagatgt
    69301 ttcatatgaa gaaactcctg agctaatcgc ggctgaaaaa gaagcggcta ttaagaaccg
    69361 tctcaagtta atcaatctac cagccagtct caagaaagct agtttggctc aagttgactt
    69421 ggatgatttg gggcgcttac cagtttttga aaagctacta gccttcgtgg agcaatatcc
    69481 agctattcga aaaggtcttt acttatatgg agactttggt gtgggtaaaa gtttcatggt
    69541 ggcggcctta gctcatgatt tatcagaaaa acgtggtgtt tcatcaactc tcctccacta
    69601 tcctagcttt gtcattgatg tcaaaaatgc tatcagtgat ggcaatgtta agaccttggt
    69661 ggatgagatt aagctgtctg aggtcctgat tttagatgat attggcgccg agcaatcaac
    69721 cgtttgggtg cgtgacgaaa tcctgcaggt cattctccaa tatcggatgc aggaaaattt
    69781 accgaccttt ttcacatcca acttcaactt tgaagatttg gagaagcatt ttgcgaaagt
    69841 gaaacatgga aatgacgaaa cctgggaagc cagacgggtc atggaacgca tccgttattt
    69901 ggctgaggag actcgtttag aaggagtaaa ccgtcgatga cagaaaccat taaattgatg
    69961 aaggctcata cttcagtgcg caggtttaaa gagcaagaaa ttccccaagt agacttaaat
    70021 gagattttga cagcagccca gatggcatca tcttggaaga atttccaatc ctactctgtg
    70081 attgtggtac gaagtcaaga gaagaaagat gccttgtatg aattggtacc tcaagaagcc
    70141 attcgccagt ctgctgtttt ccttctcttt gtcggagatt tgaaccgagc agaaaaggga
    70201 gcccgacttc ataccgacac cttccaaccc caaggtgtgg aaggtctctt gattagttcg
    70261 gtcgatgcag ctcttgctgg acaaaatgcc ttgttggcag ctgaaagctt gggctatggt
    70321 ggtgtgatta tcggtttggt tcgatacaag tctgaagaag tggcagagct ctttaaccta
    70381 cctgactaca cctattctgt ctttgggatg gcactgggtg tgccaaatca acatcatgat
    70441 atgaaaccga gactgccact agagaatgtt gtctttgagg aagaatacca agaacagtca
    70501 actgaggcaa tccaagctta tgaccgtgtt caggctgact atgctggggc gcgtgcgacc
    70561 acaagctgga gtcagcgtct agcagaacag tttggtcaag ctgaaccaag ctcaactaga
    70621 aaaaatcttg aacagaagaa attattgtag aaagtgagaa attatggccc taccaactat
    70681 tgccattgta ggacgtccca atgttgggaa atcaacccta tttaatcgga tcgctggtga
    70741 gcgaatctcc attgtagaag atgtcgaagg agtgacacgt gaccgtattt atgcaacggg
    70801 tgagtggctc aatcgttctt ttagcatgat tgatacagga ggaattgatg atgttgatgc
    70861 tcctttcatg gaacaaatca agcaccaggc agaaattgcc atggaagaag cagatgttat
    70921 cgtctttgtc gtgtccggta aggaaggaat taccgatgca gacgaatacg tagcccgtaa
    70981 gctttataag acccacaaac cagttatcct cgcagttaac aaggtagaca accctgagat
    71041 gcgaaatgat atctatgatt tctatgccct cggtttgggt gaaccactgc ctatctcatc
    71101 tgtccatggt atcggtacag gggatgtact agatgcgatt gtggaaaacc ttccaaatga
    71161 atatgaagaa gaaaatccag atgtcattaa gtttagcctg attggtcgtc caaacgttgg
    71221 aaaatcaagc ttgatcaatg ctatcttggg cgaagaccgt gttattgcta gtcctgttgc
    71281 tggaacaact cgtgatgcca ttgataccca ctttacagat acagatggtc aagagtttac
    71341 catgattgat acggctggta tgcgtaagtc tggtaaggtt tatgaaaata ctgagaaata
    71401 ctctgttatg cgtgccatgc gtgctattga ccgttcagat gtggtcttga tggtcatcaa
    71461 tgcggaagaa ggcattcgtg agtacgacaa gcgtatcgca ggatttgccc atgaagctgg
    71521 taaagggatg attatcgtgg tcaacaagtg ggatacgctt gaaaaagata accacactat
    71581 gaaaaactgg gaagaagata tccgtgagca gttccaatac ctgccttacg caccgattat
    71641 ctttgtatca gctttaacca agcaacgtct ccacaaactt cctgagatga ttaagcaaat
    71701 cagcgaaagt caaaatacac gtattccatc agctgtcttg aacgatgtca tcatggatgc
    71761 cattgccatc aacccaacac cgacagacaa aggaaaacgt ctcaagattt tctatgcgac
    71821 ccaagtggca accaaaccac caacctttgt catctttgtc aatgaagaag aactcatgca
    71881 cttttcttac ctgcgtttct tggaaaatca aatccgcaag gcctttgttt ttgaaggaac
    71941 accgattcat ctcatcgcaa gaaaacgcaa ataaaaaagt agaatctgga atgacagttc
    72001 cggatttttt tgatataata aaataataga aaacgctatc aaaagaagga gggtgatgtc
    72061 ggtgatggaa catttgttta aattcttact tttagcaccg tacttttatt ttgataactg
    72121 gattgagaag gccaacagaa atagtaagtt ttttccaatt ttttattatt tttactggtt
    72181 ttacatcccc ttctattctc tttttagcct tgcttggaca gttgtttcag ttctgttttt
    72241 caataccgtc ttgagaaatg tgacagatat caagttatgg ggcatttggt ttctttttat
    72301 tctgctagct attggtatga attggttaac ttattcctgt ttcaaagaaa tgtttcgctt
    72361 gagacaggaa ctagggaagt ctaagggtgg aaggcattga tttatatcgg tttctatttg
    72421 taggaggtgg cttatggtac ctctaaaatc atttattaca cgctattcca aggtttatat
    72481 tggtaataac atttaataga acgaaactaa agaaaacaat ttaaaagagg aggtttgtga
    72541 tggaacactt gtttaaaatg gtaatcttat taccctgttt ttactttttc agctggattg
    72601 aaagggcaaa cagagatagt aagattttct caatttttta ctatttttac tggatttaca
    72661 tcaccctcta tgctcttttt agtctggctt ggacagtttt ttcggtcctg ttgttcaata
    72721 tcgtcttgag aaatgtggca gacatcaagt cttggggtgt ttggctatta ttactactta
    72781 tcgcttttgc tagtgactgg ttagactata tctgtttcaa aaaaatgctt gacttgagac
    72841 gggaactagg gaagtctaaa ggtgtgcata aaggaaggtg taggaactaa aaaatgactg
    72901 tatctatgat ttttttatgg agctatagat acagtcattt ttattttgat tatgaaactt
    72961 gagagaaata ttcatcttgt atagtggatt gaatatggaa taatacaata caacttataa
    73021 aacattggta taaaatgctt tagatcccct aattgattcg ttcacattct attacaatct
    73081 actataataa aatgatgaga gttattacaa attataggtt tgaaaaatca ttaatttctt
    73141 tttcgagtat tttaactaat gcctcttctt tggttagtcg taataaagtt attcctttat
    73201 caatcaaatc ggagttatgt tgtagtattc ccaagcgtac ttgagagaat ccaagaatat
    73261 cgtatatttt taattcttct gctaatacca aaagttgtag ggtgattgtt tcacattctt
    73321 tgaataaatg atgttgaaaa tatacagtgg agagattggc taaaaaagat gataaaaatg
    73381 cttttgtttc tcggaagtat ttatatttct cgatggtttt cataattcta tcaataagaa
    73441 ggggaagatt ttcagaagga aagaaaaaga gaatggttcc aagcaatttc aaatcactaa
    73501 tgtaccatgt atccataggt tcaagatagt cccaaatttc ttcatacaaa tctttcaaga
    73561 cgtggttgtt tttgaatcct ttagttcgta actctgtgac aatttttgta tgacgataga
    73621 tattttgaat aggaacatcg tgatgtgtct taagatattt ttgacatttc tcagtgagtt
    73681 caaccatttt tctagtatct tgaaaagtag acggattttg gctctctaca ataatatctc
    73741 gccttttact aggatggtat tcgttgcata tatacttgaa ttctgccaag ctcatatcaa
    73801 tttgttcaag aagaaatacc atgttttcaa aactgggaat aactttaccg tgttcaatat
    73861 ttgttagagt tgttcgatgt atgacttgtc cacatacatc ttgttgggtc aatccttttg
    73921 actttcgaat ttctttaaaa atttgtccat aatcccatct catattgttc ctcctaggta
    73981 aatgtgaata ttttctacat ttataaaaaa cgtagaaaaa ggtggtatta ttatatcaaa
    74041 aaggagggaa aaagtcatgg gctttaaaaa atatttgaag aatttaccga aaaactctgg
    74101 atttttgatt tggagttgga ttcaacttat ctggtttgaa acatggtttt ggggataaag
    74161 aaattagagt ctatacataa taagtaaagg aggaatttgt atgatatacc atcgtttaga
    74221 ataagtctat atttaaaata gaagttataa ggaatcttct tgaataaaaa atgaaaggaa
    74281 acagaaaaaa tgaaaattaa gaaattattg aaaatggtta ttcctgtttt aatgataagt
    74341 gctgttggaa ctactttcgt agaagcaaat cagataggtg cttttagtaa ttttgttatt
    74401 actaccagtt ataagagaac aggttatttg actaaagaaa atgaaggtgc ggaatatatc
    74461 atgaacttaa atccttgtag aaatttacat cccatgactg ttaagcatcg tatagtaaat
    74521 tctaatggag aagctcgtag tggagaatcg ttaacaacct gtggtactcg ttcaactcat
    74581 ggtaattggg caacggttgg ctatgtttat gcagtagata tggcaagaca aaattggtgg
    74641 gatttatcag ctgccatttc aggtagttgg tcaccaaatt aattcgtaaa gtaggtataa
    74701 tttatgaaga ttcctctctt aacttttgca aggcataaat ttgtttatgt cttgcttact
    74761 ttgctttttc ttgctttggt ttatcgtgat gttttgatga cttatttctt ttttgatatt
    74821 catgcgcccg atctagctaa attcgatgga caagcaatta aaaatgactt attaaaatca
    74881 gcattagatt ttcgtattct ccagttcaat ctaggttttt atcaatcatt tattattcca
    74941 atcatcattg ttttgctagg ttttcaatat attgagctga aaaataaagt tttacgattg
    75001 agtattggaa gagaagtgag ctatcaaggg ttaaaaagaa agttgacttt gcaagttgca
    75061 agtatccctt gtttgatata tttagtgact gtgctgataa ttgcaattat aacctatttc
    75121 tttgggactt tttctcctct tgaatggaat tctctatttt ctgatgggag tggtttacaa
    75181 agactcctag atggagagat aaaaagctat ttgttcttta cttgtgtcct attaatcggt
    75241 attttcatca atgcaatcta ttttttacaa atagttgatt atgtggggaa tgtgactcgt
    75301 tcggcaatca cctatttgat gtttctttgg cttggttcta tgctgctcta tagtgccttg
    75361 ccttactata tggttcctat gacgagtttg atgcaagcta gctatgggga tgtaagtttg
    75421 atgaaactct ttactcctta tatcctttat gttgtccctt atatggtact taaaaaatat
    75481 gaagataatg tttaagaatt ttaacaatat ttggctaaag agaaagatcg ttttactact
    75541 tcgtatagtt ctgatgatga ttttgataaa ctatctattg tcaacagcgg ttcaaaagca
    75601 ggatgctgtt atctttttca agagagaatt gatttcaatt ttttcctata atgactattc
    75661 tgaagcgaat ttagaaatcc ccaaactctt gttaaacctt tcgcttttca tggtaggatg
    75721 gctctctgtc attttacttg aaagtgattt ggcagaccat taccatcact tgattcgcta
    75781 tcaatcaagc tcctttttcg attatacaag gaaacgattg gttgtcattt ctaaattttt
    75841 tactcaagat ttgtttgtct ggtttcttgg tttacttccg ctaggaattc atttcaaaac
    75901 agtcgcactt ttctttttac ttgctcagtt aatgatgttg tacttactac tgtcttatct
    75961 gatagcactg attagtgcgg gcgctggttt ttcttttttt ctctattttt tggcatttgt
    76021 gggacaagaa tggatgatgg atcatattgt aacagtgtat ttagtactct taagcttatt
    76081 agttatgttg attcttagtc gcttggaaga gaaatttaag aaaggataaa cgatgagact
    76141 tgaaattata aatggacaga aaatttatgg gaaaagacct attttaaatc agttgaattt
    76201 ggtgtttcaa tcaggaaaaa tttatggact taaaggtgat aatggatctg gcaagacggt
    76261 tcttttaaag atacttgctg gttatattaa gcttgacaaa ggaaaagttc ttcaagatgg
    76321 taaagtttac ggggtaaaaa atcattatat tcaggatgca ggaattttaa ttgaaaaagt
    76381 cgagttttta tctcatttat ccctgagaga aaatttggaa ctgttaaggt atttttcatc
    76441 taaagttacg gaaaaaagaa ttgcctattg gattcaatac tatgatttac aggaatttga
    76501 agacgttgaa taccgtcatt tatccttggg aacaaagcaa aaaatggcct tgattcaagc
    76561 ctttatttcc tctccttcta tactctttct cgatgaacct atgaatgctt tggatgagaa
    76621 aagtgtgagg ttaaccaaac aggtcatttt atcttacctg aaaaaagaaa atggtctggt
    76681 tatcctgacg tcgcacatat cggaagatat ttcagacctt tgtacagatg tattagttgt
    76741 cgaaaatgga catatacaat atgtaaagga tatacaatcc taggagatgg cttatggcac
    76801 atctaaaatc atttattaca cgctattcca aggtttatat tggtttagtt ctgctgatct
    76861 ggctgtcttt cttctttatc ccttgggata gagcgattct gggggtaagg attgacatct
    76921 tcatcataca gaaagtcttg ctagtttttg gaattctgtc cattttgatg gccttgctgt
    76981 ccaagaaagt cagtctcttt gtttttggac tgatttgctg tctttctctt tggattaact
    77041 tatttatcac atttgccatt ttgccaattt ttggcaatta aacagtcata aaagtcggag
    77101 aggttagctt gaaaactaac ctctttttcc ttttcaaaat ggggattctt ccttgaaaat
    77161 aatcagtaat tgtgctaaaa ttaaaggaac attctaaaat attcggaatt taaagtaagg
    77221 aaaaacatgg ctaatatttt aaaaacaatt atcgaaaatg ataaaggaga aatccgtcgt
    77281 ctggaaaaga tggctgacaa ggttttcaaa tacgaagacc aaatggctgc tttgactgac
    77341 gaccaactaa aagcaaaaac agttgaattt aaggaacgtt atcaaaatgg agaatcactg
    77401 gattcattgc tttacgaagc atttgcggtt gtccgtgaag gtgccaaacg tgtcctaggt
    77461 ctcttccctt ataaggttca ggtcatgggg gggattgttc ttcaccatgg tgacgtgcca
    77521 gagatgcgta caggggaagg gaaaaccttg actgcgacca tgccggtata cctcaatgcc
    77581 ctttcaggta aaggggttca cgtagttacg gttaatgaat acctgtcaga acgtgacgcg
    77641 actgagatgg gtgaattgta ctcttggctt ggtttgtcag tagggattaa cttggctacc
    77701 aaatctccaa tggagaaaaa agaagcctat gagtgtgata ttacttactc aactaactca
    77761 gaaatcggat ttgactacct tcgtgacaac atggtcgttc gcgctgaaaa catggtacaa
    77821 cgtccgctta actatgcctt ggtcgatgag gttgactcta tcttgattga cgaggctcgt
    77881 acacctttga ttgtatcagg tgccaatgcg gttgaaacca gtcagttgta tcacatggca
    77941 gaccactatg taaaatcttt gaacaaagat gactacatca tcgatgtgca gtctaagact
    78001 attggtttgt ctgattcagg gattgacagg gctgaaagct acttcaaact tgaaaacctc
    78061 tatgacatcg aaaacgtggc tttgacccac tttatcgata acgcccttcg tgccaactac
    78121 atcatgcttc tcgatattga ctatgtggtg agcgaagagc aagaaatctt gattgtcgac
    78181 caatttacag gtcgtaccat ggaaggtcgt cgttattctg atggattgca ccaagctatt
    78241 gaagccaaag aaggtgtgcc aatccaggat gaaaccaaga catctgcctc aatcacgtac
    78301 caaaaccttt tccgtatgta caaaaaattg tctggtatga cgggtacagg taagactgag
    78361 gaagaagaat ttcgtgaaat ctacaacatt cgtgttattc caatcccaac aaaccgtcct
    78421 gttcaacgta ttgaccactc agaccttctt tatgcaagta tcgaatctaa gtttaaagcg
    78481 gttgtcgaag acgttaaggc tcgttaccaa aagggtcaac ctgtcttggt tggtacagta
    78541 gcggttgaaa ctagtgacta catttctaag aaattggttg cagctggtgt tcctcacgaa
    78601 gtcttgaatg ccaaaaacca ctatagagaa gcccaaatca tcatgaatgc tggtcaacgt
    78661 ggtgccgtta ccatcgcaac caacatggcg ggtcgtggta ccgacatcaa gcttggtgaa
    78721 ggtgttcgtg aacttggagg actttgtgtt attggtacag aacgtcatga aagtcgtcgt
    78781 atcgataacc agcttcgtgg acgttcaggt cgtcaaggag atccaggtga gtcacaattc
    78841 tacctatctc ttgaagatga tttgatgaaa cgttttggtt ctgaacgctt gaagggaatc
    78901 tttgaacgct tgaacatgtc tgaagaggcc attgagtctc gcatgttgac gcgtcaggtt
    78961 gaagcagctc agaaacgtgt cgaaggaaat aactacgata cccgtaaaca agtccttcaa
    79021 tacgacgatg tcatgcgtga acaacgtgag attatctata ctcaacgtta tgatgtcatt
    79081 actgcagacc gtgacttggc acctgaaatt caggcaatga tcaaacgcac gattggtcgt
    79141 gtcgttgacg gtcatgcgcg tgctaaacaa gatgagaaac tagaggcaat tttgaacttc
    79201 gctaagtaca acttgcttcc tgaagattct attacgatgg aagacttgtc aggcttgtct
    79261 gataaggcca tcaaggaaga gcttttccaa cgtgccttga aggtttacga tagtcaggtt
    79321 tcaaaactac gcgatgaaga agcagttaaa gaattccaaa aagttttgat tctacgagtg
    79381 gtggataaca agtggacaga tcatatcgat gcccttgatc aattgcgtaa cgcggttgga
    79441 cttcgtggct atgctcagaa caaccctgtt gttgagtatc aggcagaagg tttccgtatg
    79501 tttaatgata tgattggttc gattgagttt gatgtgacac gcttgatgat gaaagcacaa
    79561 attcatgaac aagaaagacc acaggcagaa cgtcatatca gtacaacagc gactcgcaat
    79621 atcgctgctc accaagcaag tatgccagaa gatttggatt tgagccagat tggacgcaat
    79681 gaactttgcc catgtggttc tggtaagaaa tttaaaaact gtcacggtaa aagacaataa
    79741 aatgagatag tttagaggcg gatatcttgt gaaaagtaaa tttttactgg gtatccgttt
    79801 gctttataag gagatgagtt atggtattta cagcaaaaag ctctaaaata aatatagaag
    79861 aagttcgtgc cttgtcaaaa ttagaaggtc aggctttgga gaggaaatca cagcgagatc
    79921 aagagctaga agccattata cgtggagaag accagcgaat tctcttggta atcgggccat
    79981 gctcatctga caacgaagaa gctgtccttg aatacgctaa gcgtttggca gtcctacaag
    80041 aagaagtggc agatcgtatc tttatggtta tgcgtgttta tactgccaaa ccccgtacca
    80101 acggagatgg ctataagggc ttgattcacc agcctaacgc gacagaagcg cctagtctta
    80161 tcaatggaat caaagccgtt cgccatcttc actatcgtgt catcacagaa acagggatga
    80221 caactgctga tgaaatgctt tatcctgaaa accttccgct tgtagatgat ttgatttctt
    80281 acatggcagt tggtgcccgt tcagttgaag accagcaaca ccgctttgtg gcaagtgggg
    80341 caggattttc tactggtttt aaaaatccaa cctctggaaa tctcaatgtc atgtttaatg
    80401 ggatttatgc tgctcaaaac aaacaaagtt tccttttctt aggaaaagaa gtagaaacaa
    80461 ctgggaaccc gctttcacac gctattcttc gtggtgctct taatgagtat ggaaaaaata
    80521 ttcccaacta ctattatgac aatttaattg ataccattgc ccagtatgag aaaatgggct
    80581 tggaaaatcc ttttatcatc attgatacca atcatgacaa ttctggtaag cagtatattg
    80641 aacagatccg aattgtccgc cagaccttga ttaaccgtgc ttggaatgaa aaaattaagc
    80701 agttcgttcg tggttttatg attgagtctt atctggaaga tggtcgacaa aatgagccag
    80761 aagtatttgg taagtctatc acagaccctt gcctgggttg ggataacaca gaagctcttg
    80821 tcagagaaat ttacaaaacg ttaggagaat aagatggcat ttattgaaaa aggtcaagaa
    80881 atcgatatgg aagtcatcaa ggctgaaacc caattgtctg cggaagcctt gagactcaag
    80941 gaaagccgtg acagggaatt ggcagatatt atttcagggg aagatgaccg tattctcttg
    81001 gtgattggtc cttgctcttc tgataatgaa gaggcggtct tggaatatgc tcgccgttta
    81061 tccgccttgc aaaagaaggt agcggacaag attttcatgg tcatgcgcgt gtatactgct
    81121 aagcctcgta ccaatggaga cggctataaa ggattggttc accagccaga tacttctaag
    81181 gctccaagcc tgattaacgg cttgcaggct gtgcgccagt tgcactaccg cgtgattaca
    81241 gagactggtt tgacaacggc agatgagatg ctttatccgt caaatctgat cttggtggat
    81301 gacttggtca gctaccatgc cgttggagct cgttctgtgg aagaccaaga gcaccgcttt
    81361 gtggcttctg ggattgatgc accagtaggg atgaaaaatc caacctcagg aaatttgggt
    81421 gttatgttta acgccatcta tgctgctcaa aacaagcaaa ccttccttta tcatgggcag
    81481 gaagttgaga catcaggtaa tcctttggcc catgttatcc tccgtggagc agtcaacgag
    81541 tatggcaatt atatgccgaa ttactactat gaaaacctac tccaagccat tgaacgctat
    81601 gaaaccatgg gacttgaaaa tccttttatc ctcattgaca ccaaccatga taactcaggc
    81661 aagcaatata tggagcagat tcgaattgtt cgccagacct tgcagaatcg tgattggaat
    81721 gagaaaatta aaaagacggt tcgaggattt atgattgaat cttacctagc agatggtcgt
    81781 caaaaccaac cagaaatctt tggttgctct attactgacc cttgcctagg ttgggaaaat
    81841 acagaggcct tggtagaaga gatttatgtt accttgacaa aataagtgaa aaggatggag
    81901 ttggggaatc tcaactcctt ttgatgagaa tgatagttgg acacggaatt gacatcgaag
    81961 aattggcttc gatagaaagc gcagttacac gacatgaagg atttgctaag cgtgtactga
    82021 ccgctcagga aatggagcgc ttcaccagtc tcaaaggacg caggcaaata gaatatttag
    82081 ctggtcgctg gtcggctaag gaggcctttt ccaaggctat gggaacgggc attagcaagc
    82141 tcggttttca ggatttggaa gtcttgaaca atgaacgtgg ggcgccttat tttagtcagg
    82201 caccattttc aggaaagatt tggctgtcta tcagccacac cgatcagttt gtgacagcca
    82261 gtgtcatttt ggaggaaaat catgaaagct agtccacata gaccaaccaa ggctctgatt
    82321 catctgggag ctattcgaca aaatattcag caaatggggg ctcatatccc tcaaggaacg
    82381 ctcaagtggg ctgtggtcaa ggccaatgct tatggtcatg gagctgttgc cgttgccaag
    82441 gcaattcaag atgatgttga tggcttttgc gtttccaata tcgatgaagc cattgaactc
    82501 agacaagctg gactcagcaa gccaatcctc attttaggag tttctgaaat cgaagctgtt
    82561 gctctagcta aagaatatga cttcaccttg acagtggctg gactggagtg gattcaagca
    82621 ctcttagata aggaagtgga cctaactgga ttgacagtcc acctcaagat tgattcaggg
    82681 atgggacgga ttggttttag agaggtcagt gaggttgagc aggctcaaga tttgctccaa
    82741 aaacacggtg tttgtgttga aggaatcttt acccactttg ctactgctga tgaggaatca
    82801 gatgactatt ttaatgccca gttagaacgg tttaaaacta ttttagctag tatgaaggaa
    82861 gttccagagc tggttcatgc tagcaattct gcaacgactc tttggcatgt agagactatt
    82921 ttcaatgcgg ttcgtatggg agatgccatg tatggcctca atccaagtgg agcggtcttg
    82981 gatttgcctt atgatttgat accggccttg accttggagt ctgctctggt tcatgtcaag
    83041 acagttccag ctggagcttg catgggctat ggagcaactt atcaagcgga tagcgagcaa
    83101 gtcatcgcga ccgtgccaat cgggtatgca gatggatgga caagagacat gcaaaatttc
    83161 tctgtcttgg tagatggcca agcttgccca attgtcggca gggtttcgat ggaccaaatc
    83221 actattcgat tgcctaagct ttatccgcta ggaaccaagg taaccttgat tggctccaat
    83281 ggggataagg aaatcactgc aactcaggta gcgacctacc gcgtcaccat taactatgag
    83341 gtggtttgcc tcctcagcga ccgtattccg agagaatatt attagaaaag aaaggagtgg
    83401 agcatgaatc tacatcaacc cttgcatgtc ttgcctggtg tgggaccaaa gtcagcagaa
    83461 aaatacgcca aactaggaat tgaaaacttg caagatctct tgctctactt tcctttccgt
    83521 tatgaagact tcaaaaccaa gcaggtgctg gaactagaag acggtgagaa ggcagttctt
    83581 tctggtcagg tagtgactcc tgctagtgtc cagtattatg gtttcaagcg caatcgcctg
    83641 cgttttagtc tcaagcaggg agaggtcgtt tttgcggtga atttctttaa ccagccctat
    83701 ctggctgata aaatagagtt gggagcaact cttgctgtct ttggaaaatg ggaccgcgct
    83761 aaggctagtc tgactgggat gaaggttctg gctcaggtag aagatgacct ccagcctgtc
    83821 tatcgtctgg ctcagggaat cagtcaggcc agtctggtta aggtcatcaa gacggctttt
    83881 gatcagggac tagacctctt gatagaagaa aatctgcccc agtctttact agacaaatac
    83941 aaactcatgt cccgttgtca ggcagtccga gctatgcatt ttccaaagga tttggcagaa
    84001 tacaagcagg ctcttcgccg tataaagttt gaggaactct tttatttcca aatgcagctg
    84061 cagatgctca agtctgaaaa tagagttcag ggaagtggtc tggttctgaa ttggtctcag
    84121 gaaaaagtga cagcagttaa agtaagtctt ccttttgccc tgacccaagc tcaggaaaag
    84181 agtttgcagg aaattttaac tgatatgaag tccgaccacc acatgaatcg tctcctacaa
    84241 ggggatgtgg ggagtggaaa aacggtagtc gctggcttgg ccatgtttgc ggcagtgaca
    84301 gcaggttatc aggctgccct aatggtacca acagaaatcc tcgcagagca acactttgag
    84361 agtttacaga acctttttcc caatttgaaa ctggctctct tgacaggttc cttgaaagct
    84421 gcagaaaaga gagaggtctt ggagaccatt gccaagggtg aggccgattt gattatcgga
    84481 acccacgctc tgatacaaga tggggtggag tatgctcgtc ttggtttgat tattatcgat
    84541 gagcagcacc gttttggtgt ggggcaaagg cgtattttac gggaaaaagg cgacaatcca
    84601 gatgtcctca tgatgacggc gactcccatt ccacggacgc ttgccatcac agcctttgga
    84661 gatatggatg tttccattat cgaccagatg ccagcaggtc ggaagcctat tgtgacgcgc
    84721 tggatcaaac atgagcaact acctcaggtc ttgacttggt tagaggggga aattcaaaaa
    84781 ggttcccaag cctatgtcat ctctcctttg attgaagaat cagaagctct agatttgaaa
    84841 aatgccattg ccttatcaga ggagttgacg actcattttg caggcaaggc agaggtggct
    84901 cttctacatg gtaggatgaa gagtgacgaa aaagaccaga tcatgcagga tttcaaggag
    84961 agaaagacgg atattctggt ttcgacgacg gttattgagg ttggggtcaa tgttcccaat
    85021 gcgactgtca tgattatcat ggatgccgat cgcttcggtc tcagtcaact tcaccagctt
    85081 agaggtcgtg tcggtcgggg ggacaagcag tcctacgctg ttctcgttgc caatcccaag
    85141 acggattctg ggaaagaccg catgcgcatc atgacagaaa cgaccaatgg atttgtcctt
    85201 gcggaggaag atttgaaaat gcgtggttct ggtgagattt ttggaaccag acagtcagga
    85261 cttccagagt tccaagtggc tgatattatc gaagattttc cgattttaga agaagcaaga
    85321 aaggttgcta gctacattag ttctatagaa acttggcaag aagatccaga gtggcgcatg
    85381 attgcccttc atctggaaaa gaaagaacat ctggattaag ctttctctaa ggaaaactta
    85441 agctagtttt tagatttggc tcttatacta aagtcatcaa aaagaaacga ggactctcat
    85501 atgacagtaa cgattaaagt aaattaccaa accactttcc aaaagaagga agcaaaaaac
    85561 tagtataaac agaagagaga gcgaaatgct cttttttcgt ttctaaaact actttcagcc
    85621 catcatccta aaagtaaaga atctaaattc actttctatt tacccttctt tcttgcattg
    85681 attacataga tatgctacag ttgtggtaac gattacaaaa taaaaggagc atgctatgaa
    85741 aaatccagct ttgctagaag aaattaagac ctatagagga agggatgagg ttccggaaga
    85801 ctttgatgat ttctgggatg gggaagtgaa aaatgtttcc acgcttccat cctaccactt
    85861 ggaggaaaga gatttccaca ttcctcaagt caagtgctat gagttaacat ttgaaggaag
    85921 caagaaagga aaggtctatg cacgcattgt tcttccaaag agtgaggaga aggttccact
    85981 aatcttccat tttcatggtt atatgggacg tggctgggac tgggccgaca tgctgggctt
    86041 caccgtagct ggttacggtg ttgtttccat ggatgtgcgg ggccagtcag gttactcaca
    86101 agacggcttg cgttctcctt taggaaatac cgtgaagggg catattatcc gtggtgctgt
    86161 ggaaggtcgg gaccacctct tttataagga tgtttatctg gatatttacc agttggtcga
    86221 aattgttgct agtctgtctc aggttgatga gaagcgtctt tctagctatg gtgcctcaca
    86281 aggaggggct ctagctctag ttgcagcagc gctcaatcct cgaattcaga aaacagttgc
    86341 catttatccc ttcttgtcag acttcagacg ggtgattgag attggtaata ctagcgaggc
    86401 ttacgacgaa cttttccgtt atttcaagtt tcacgacccc ttccatgaaa cagaggagga
    86461 aatcatggcg acccttgcct atatcgatgt caaaaatctt gcccatcgta tccaaggtga
    86521 ggttaagatg attacgggct tggacgacga tgtttgctat cccattaccc agtttgcgat
    86581 ttataatcgt ctgacctgcg ataaaaccta tcgcatcatg cctgagtatg ctcacgaagc
    86641 catgaatgta tttgtcaatg accaagtcta caactggctc tgtggaagtg agattccttt
    86701 taaatatcta aaataaggag tcgactctaa gcacaaaatc ttaaaaatta caaacacgca
    86761 tagtatcagg ggattaagaa aacttgatac tatgcgtttt atcatggaaa tatagtaaaa
    86821 tgaaacaaga acaggacaaa tcgatcagga gagtcaaatc gatttctaac aatgttttag
    86881 aagtagatgt gtactattct agtttcaatc tattatattt atagaatttt ttgttgctag
    86941 atttgtcaaa ttgcttaaaa taattttttt cagaaagcaa aagccgatac ctatcgagta
    87001 gggtagttct tgctatcgtt aggcttgtct gtaggtgtta atacttttca aaaatctctt
    87061 caaaccacgt cagcttcgcc ttgccgtata tatgttactg acttcgtcag ttctatctgc
    87121 cacctcaaaa cggtgttttg agctgacttt gtcagtctta tctacaacct caaaacagtg
    87181 ttttgagcat catgcggcta gcttcttagt ttgctctttg attttcattg agtataaaaa
    87241 cagatgagtt tctgttttct ttttatggac tataaatgtt cagctgaaac tactttcaag
    87301 gacattatta tataaaagaa ttttttgaaa ctaaaatcta ctatattaca ctatattgaa
    87361 agcgttttaa aaatgaggta taataaattt attaacactt ataaaaagtg atagaatcta
    87421 tctttatgta tatttaaaga tagattgctg taaaaatagt agtagctatg cgaaataaca
    87481 gatagagaga agggattgaa gcttagaaaa ggggaataat atgatattta aggcattcaa
    87541 gacaaaaaag cagagaaaaa gacaagttga actacttttg acagtttttt tcgacagttt
    87601 tctgattgat ttatttcttc acttatttgg gattgtcccc tttaagctgg ataagattct
    87661 gattgtgagc ttgattatat ttcccattat ttctacaagt atttatgctt atgaaaagct
    87721 atttgaaaaa gtgttcgata aggattgagc aggaagtatg gtgtaaatag cataggctga
    87781 tgtccatcat ttgcttataa agagatattt tagtttaatt gcagcggtgt cctggtagat
    87841 aaactagatt ggcaggagtc tgattggaga aaggagaggg gaaatttggc accaatttga
    87901 gatagtttgt ttagttcatt tttgtcattt aaatgaactg tagtaaaaga aagttaataa
    87961 aagacaaact aagtgcattt tctggagtaa atgtcttatt tcagaaatcg ggatatagat
    88021 atagagagga tcagtatgaa tcggagtgtt caagaacgta agtgtcgtta tagcattagg
    88081 aaactatcgg taggagcggt ttctatgatt gtaggagcag tggtatttgg aacgtctcct
    88141 gttttagctc aagaaggggc aagtgagcaa cctctggcaa atgaaactca actttcgggg
    88201 gggagctcaa ccctaactga tacagaaaag agccagcctt cttcagagac tgaactttct
    88261 ggcaataagc aagaacaaga aaggaaagat aagcaagaag aaaaaattcc aagagattac
    88321 tatgcacgag atttggaaaa tgtcgaaaca gtgatagaaa aagaagatgt tgaaaccaat
    88381 gcttcaaatg gtcagagagt tgatttatca agtgaactag ataaactaaa gaaacttgaa
    88441 aacgcaacag ttcacatgga gtttaagcca gatgccaagg ccccagcatt ctataatctc
    88501 ttttctgtgt caagtgctac taaaaaagat gagtacttca ctatggcagt ttacaataat
    88561 actgctactc tagaggggcg tggttcggat gggaaacagt tttacaataa ttacaacgat
    88621 gcacccttaa aagttaaacc aggtcagtgg aattctgtga ctttcacagt tgaaaaaccg
    88681 acagcagaac tacctaaagg ccgagtgcgc ctctacgtaa acggggtatt atctcgaaca
    88741 agtttgagat ctggcaattt cattaaagat atgccagatg taacgcatgt gcaaatcgga
    88801 gcaaccaagc gtgccaacaa tacggtttgg gggtcaaatc tacagattcg gaatctcact
    88861 gtgtataatc gtgctttaac accagaagag gtacaaaaac gtagtcaact ttttaaacgc
    88921 tcagatttag aaaaaaaact acctgaagga gcgactttaa cagagaaaac ggacatattc
    88981 gaaagcgggc gtaacggtaa accaaataaa gatggaatca agagttatcg tattccagca
    89041 cttctcaaga cagataaagg aactttgatc gcaggtgcag atgaacgccg tctccattcg
    89101 agtgactggg gtgatatcgg tatggtcatc agacgtagtg aagataatgg taaaacttgg
    89161 ggtgaccgag taaccattac caacttacgt gacaatccaa aagcttctga cccatcgatc
    89221 ggttcaccag tgaatatcga tatggtgttg gttcaagatc ctgaaaccaa acgaatcttt
    89281 tctatctatg acatgttccc agaagggaag ggaatctttg gaatgtcttc acaaaaagaa
    89341 gaagcctaca aagaaatcga tggaaaaacc tatcaaatcc tctatcgtga gggagaaaag
    89401 gaagcttata ccattcgaga aaatggtact gtctatacac cagatggtaa ggcgacagac
    89461 tatcgcgttg ttgtagatcc tgttaaacca gcctatagcg acaagggtga tctatacaag
    89521 ggtgaccaat tactaggaaa tatctacttc acaacaaaca aaacttctcc atttagaatt
    89581 gccaaggata gctatctatg gatgtcctac agtgatgacg acgggaagac atggtcagcg
    89641 cctcaagata ttactccgat ggtcaaagcc gattggatga aattcttggg tgtaggtcct
    89701 ggaacaggaa ttgtacttcg gaatgggcct cacaagggac ggattttgat accggtttat
    89761 acgactaata atgtatctca cttagatggc tcgcaatctt ctcgtgtcat ctattcagat
    89821 gatcatggaa aaacttggca tgctggagaa gcggtcaacg ataaccgtca ggtagacggt
    89881 caaaagatcc actcttctac gatgaacaat agacgtgcgc aaaatacaga atcaacggtg
    89941 gtacaactaa acaatggaga tgttaaactc tttatgcgtg gtttgactgg agatcttcag
    90001 gttgctacaa gtaaagacgg aggagtgact tgggagaagg atatcaaacg ttatccacag
    90061 gttaaagatg tctatgttca aatgtctgct atccatacga tgcacgaagg aaaagaatac
    90121 atcatcctca gtaatgcagg tggaccgaaa cgtgaaaatg ggatggtcca cttggcacgt
    90181 gtcgaagaaa atggtgagtt gacttggctc aaacacaatc caattcaaaa aggagagttt
    90241 gcctataatt cgctccaaga attaggaaat ggggagtatg gtatcttgta tgaacatact
    90301 gaaaaaggac aaaatgccta taccctatca tttagaaaat ttaattggga ctttttgagc
    90361 aaagatctga tttctcctac cgaagcgaaa gtgaagcgaa ctagagagat gggcaaagga
    90421 gttattggct tggagttcga ctcagaagta ttggtcaaca aggctccaac ccttcaattg
    90481 gcaaatggta aaacagcacg cttcatgacc cagtatgata caaaaaccct cctatttaca
    90541 gtggattcag aggatatggg tcaaaaagtt acaggtttgg cagaaggtgc aattgaaagt
    90601 atgcataatt taccagtctc tgtggcgggc actaagcttt cgaatggaat gaacggaagt
    90661 gaagctgctg ttcatgaagt gccagaatac acaggcccat tagggacatc cggcgaagag
    90721 ccagccccga cagtagagaa gccagaatat acaggtccat tagggacatc cggtgaagag
    90781 ccagctccaa cagtagagaa gccagaattt acagggggag ttaatggtac agagccagct
    90841 gttcatgaaa tcgcagagta taagggatct gattcgcttg taactcttac tacaaaagaa
    90901 gattatactt acaaagctcc tcttgctcag caggcacttc ctgaaacagg aaacaaggag
    90961 agtgacctcc tagcttcact aggactaaca gctttcttcc ttggtctgtt tacgctaggg
    91021 aaaaagagag aacaataaga gaagaattct aaacatttga ttttgtaaaa atagaaggag
    91081 atagcaggtt ttcaagcctg ctatcttttt ttgatgacat tcaagctgat acgaaatcat
    91141 aagaggtctg aaactacttt cagagtagtc tgttctataa aatatagtag attgaaataa
    91201 gatgtgaaca actctatcag gaaagtcaaa ttaatttata gaaaaatttt agcagttaag
    91261 gtgtactgtt atagattcaa tatattatga gactattaac cttgtcttct cctaaaattg
    91321 actttcttgt tttcttatct tgtccactcg aaacaagtat tgtaagaatt tgattatttt
    91381 tgaaagtact tttaatatat ttgatatagt taaaaaaatt taaaactaaa ttccaaatta
    91441 gaaaaagact tgaaatac
//
LOCUS       DBEJHE010000005        83862 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC4 isolate 671759
            SAMN38261586-rid24793303.denovo.05, whole genome shotgun sequence.
ACCESSION   DBEJHE010000005 DBEJHE010000000
VERSION     DBEJHE010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261586
            Sequence Read Archive: SRR26833752
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 83862)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 83862)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576136.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576136.1
            Genome Coverage       :: 109x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 19:48:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,067
            CDSs (total)                      :: 2,029
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 131
            CDSs (without protein)            :: 131
            Pseudo Genes (ambiguous residues) :: 0 of 131
            Pseudo Genes (frameshifted)       :: 64 of 131
            Pseudo Genes (incomplete)         :: 59 of 131
            Pseudo Genes (internal stop)      :: 46 of 131
            Pseudo Genes (multiple problems)  :: 32 of 131
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..83862
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261586-rid24793303.denovo.05"
                     /strain="GPSC4"
                     /isolate="671759"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            1..109
                     /locus_tag="ACL3EZ_000462"
                     /pseudo
     CDS             1..109
                     /locus_tag="ACL3EZ_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612110.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            112..1125
                     /locus_tag="ACL3EZ_000463"
                     /pseudo
     CDS             112..1125
                     /locus_tag="ACL3EZ_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259617.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004601 - peroxidase activity [Evidence
                     IEA];
                     GO_function: GO:0020037 - heme binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Dyp-type peroxidase"
     gene            1100..1678
                     /locus_tag="ACL3EZ_000464"
     CDS             1100..1678
                     /locus_tag="ACL3EZ_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron permease"
                     /protein_id="HGR0392092.1"
                     /translation="MVRNYWKAKSWLLVLALSFLILSPAGAQESLSFFFVKITDASKT
                     VKNGGQTETQKLVTKMASDFERVENKDSEVGKIVKEKLALSGDITEAKLTEISSALLA
                     FEKEQNPVDLDAEKEKLVNRLSPRFETLEQAIASKDLEKVREAFKKMNSTWTINESVV
                     RDNSTAHYGRVETAISFLPSSMETEPTDESGT"
     gene            complement(1735..1977)
                     /locus_tag="ACL3EZ_000465"
     CDS             complement(1735..1977)
                     /locus_tag="ACL3EZ_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019770973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HGR0392093.1"
                     /translation="MKKDIHPEYRPVVFMDTTTGYQFLSGSTKRSNETVEFEGETYPL
                     IRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLK"
     gene            complement(2073..3008)
                     /locus_tag="ACL3EZ_000466"
     CDS             complement(2073..3008)
                     /locus_tag="ACL3EZ_000466"
                     /EC_number="3.1.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004527 - exonuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008441 - 3'(2'),5'-bisphosphate
                     nucleotidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HGR0392094.1"
                     /translation="MEICQQILEKIKEYDTIIIHRHMKPDPDALGSQVGLKALLEHHF
                     PEKTIKAVGFDEPTLTWMAEMDLVEDRAYQGALVIVCDTANTARIDDKRYSQGDFLIK
                     IDHHPNDDVYGDLSWVDTSSSSASEMITLFAQTTQLALADRDAELLFAGIVGDTGRFL
                     YPSTTARTLRLAAYLREHNFDFAALTRKMDTMSYKIAKLQGYIYDHLEVDENGAARVI
                     LSQEVLKQYNVTDAETAAIVGAPGRIDRVSLWGIFVEQADGHYRVRLRSKIHPINEIA
                     KKHDGGGHPLASGANSYSLEENEIIYQKLKNLLKN"
     gene            3112..3555
                     /locus_tag="ACL3EZ_000467"
     CDS             3112..3555
                     /locus_tag="ACL3EZ_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HGR0392095.1"
                     /translation="MALAKIVFASMTGNTEEIADIVADKLRDLGLDVDVDECTTVDAS
                     DFLEADIAIVATYTYGDGELPDEMMDFYEDLADLNLNGKIYGVVGSGDTFYDEFCKAV
                     DDFDRVFVSTGAEKGSECVKVDLSAEEEDIERLEQFAEELVAKVG"
     gene            3671..3937
                     /locus_tag="ACL3EZ_000468"
     CDS             3671..3937
                     /locus_tag="ACL3EZ_000468"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HGR0392096.1"
                     /translation="MDLDIIRQEIDQIDDQIVKLLEERMHLVEGVVAYKKASGKPILD
                     TKREEVIFEKVGSRVEDKRYQETIVATFSDILKRSRDYQDQNIK"
     gene            3934..4308
                     /gene="crcB"
                     /locus_tag="ACL3EZ_000469"
     CDS             3934..4308
                     /gene="crcB"
                     /locus_tag="ACL3EZ_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HGR0392097.1"
                     /translation="MKKEQFYPLGIFLAAMLGGLVRYLVSTWLPASPDFPWGTLFVNY
                     LGIFCLIFLVKGYLVYKGTSKGLILALGTGFCGGLTTFSSLMLDTVKLLDTGRYFSLV
                     LYLLLSIGGGLLLAYFLGRKKW"
     gene            4302..4631
                     /gene="crcB"
                     /locus_tag="ACL3EZ_000470"
     CDS             4302..4631
                     /gene="crcB"
                     /locus_tag="ACL3EZ_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HGR0392098.1"
                     /translation="MVIVYLAIACGFGALVRYLFSRYNQASKLPLGTLIANLLGCFLI
                     GVFYNHVESKEVYAILATGFCGGLTTFSTLNDELQRLLSDKKVFYSYLTLTYIGGLVA
                     IFLGILL"
     gene            4750..5097
                     /gene="rplS"
                     /locus_tag="ACL3EZ_000471"
     CDS             4750..5097
                     /gene="rplS"
                     /locus_tag="ACL3EZ_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000311 - plastid large ribosomal subunit
                     [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HGR0392099.1"
                     /translation="MNPLIQSLTEGQLRTDIPSFRPGDTVRVHAKVVEGNRERIQIFE
                     GVVIARKGAGISENYTVRKISNGVGVERIFPIHTPRVEKIEVVRYGKVRRAKLYYLRA
                     LQGKAARIKEIRR"
     gene            5139..5210
                     /locus_tag="ACL3EZ_000472"
     tRNA            5139..5210
                     /locus_tag="ACL3EZ_000472"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:5172..5174,aa:Arg,seq:cct)
     gene            complement(5265..6071)
                     /gene="yidA"
                     /locus_tag="ACL3EZ_000473"
     CDS             complement(5265..6071)
                     /gene="yidA"
                     /locus_tag="ACL3EZ_000473"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000023490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HGR0392100.1"
                     /translation="MSIKLIAVDIDGTLVNSQKEITPEVFSAIQDAKEAGVKVVIATG
                     RPIAGVAKLLDDLQLRDQGDYVVTFNGALVQETATGHEIISESLTYEDYLDMEFLSRK
                     LGVHMHAITKDGIYTANRNIGTYTVHESTLVSMPIFYRTPEEMAGKEIVKCMFIDEPE
                     ILDAAIEKIPAEFYERYSINKSAPFYLELLTKNVDKGSAITHLAEKLGLTKDETMAIG
                     DEENDRAMLEVVGNPVVMENGNPEIKKIAKYITKTNDESGVAHAIRTWVL"
     gene            complement(6084..7388)
                     /locus_tag="ACL3EZ_000474"
     CDS             complement(6084..7388)
                     /locus_tag="ACL3EZ_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HGR0392101.1"
                     /translation="MNEKVFRDPVHNYIHVNNQIIYDLINTKEFQRLRRIKQLGTSSY
                     TFHGGEHSRFSHCLGVYEIARRITEIFEEKYPEEWNPAESLLTMTAALLHDLGHGAYS
                     HTFEHLFDTDHEAITQEIIQNPETEIHQVLLQVAPDFPEKVASVIDHTYPNKQVVQLI
                     SSQIDADRMDYLLRDSYFTGASYGEFDLTRILRVIRPVENGIAFQRNGMHAIEDYVLS
                     RYQMYMQVYFHPATRAMEVLLQNLLKRAKELYPEDKNFFARTSPHLLPFFEKNVTLTD
                     YLALDDGVMNTYFQLWMTSPDKILADLSQRFVNRKVFKSITFSQEDQDQLTSMRKLVE
                     DIGFDPDYYTAIHKNFDLPYDIYRPESQNPRTQIEILQKNGELAELSSLSPIVQSLAG
                     SRHGDNRFYFPKEMLDQNSIFASITQQFLHLIENDHFTPNKN"
     gene            7460..7837
                     /locus_tag="ACL3EZ_000475"
     CDS             7460..7837
                     /locus_tag="ACL3EZ_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HGR0392102.1"
                     /translation="MKIRMRNTIQFDEQLEVIDQLYDVEVHEKGDYSYLLFYNEEKEK
                     VVIKFHGQELVMSRFSNPKTIMRFLKDSDSLAYIPTPMGMQEFIIQTSHYQVDRQKIE
                     LDYQLQNQEGHPFASYQLEITWG"
     gene            7928..8260
                     /locus_tag="ACL3EZ_000476"
     CDS             7928..8260
                     /locus_tag="ACL3EZ_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014637934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HGR0392103.1"
                     /translation="MEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIAEE
                     FGVSRQAVYDNIKRTEKILEDYEMKLHMYSDYIVRSQIFDQILERYPKDDFLQEQIEI
                     LTSIDNRE"
     gene            8272..9843
                     /gene="ffh"
                     /locus_tag="ACL3EZ_000477"
     CDS             8272..9843
                     /gene="ffh"
                     /locus_tag="ACL3EZ_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002902912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0048501 - signal recognition particle,
                     plasma membrane targeting [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005048 - signal sequence binding
                     [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HGR0392104.1"
                     /translation="MAFESLTERLQNVFKNLRKKGKISESDVQEATKEIRLALLEADV
                     ALPVVKDFIKKVRERAVGHEVIDTLNPAQQIIKIVDEELTAVLGSDTAEIIKSPKIPT
                     IIMMVGLQGAGKTTFAGKLANKLKKEENARPLMIAADIYRPAAIDQLKTLGQQIDVPV
                     FALGTEVPAVEIVRQGLEQAQTNHNDYVLIDTAGRLQIDELLMNELRDVKALAQPNEI
                     LLVVDAMIGQEAANVAREFNAQLEVTGVILTKIDGDTRGGAALSVRHITGKPIKFTGT
                     GEKITDIETFHPDRMSSRILGMGDMLTLIEKASQEYDEQKALEMAEKMRENTFDFNDF
                     IDQLDQVQNMGPMEDLLKMIPGMANNPALQNMKVDERQIARKRAIVSSMTPEERENPD
                     LLNPSRRRRIAAGSGNTFVEVNKFIKDFNQAKQLMQGVMSGDMNKMMKQMGINPNNLP
                     KNMPNMGGMDMSALEGMMGQGGMPDLSALGGAGMPDMSQMFGGGLKGKIGEFAMKQSM
                     KRMANKMKKAKKKRK"
     gene            complement(10038..11321)
                     /locus_tag="ACL3EZ_000478"
     CDS             complement(10038..11321)
                     /locus_tag="ACL3EZ_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007554578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="solute carrier family 23 protein"
                     /protein_id="HGR0392105.1"
                     /translation="MKQESTVDLLLDVDQRPSAGKGILLSFQHVFAMFGATILVPLIL
                     GMPVSVALFASGVGTLIYMIATGFKVPVYLGSSFAFITAMSLAMKEMGGDVSAAQTGV
                     ILTGLVYVLVATSIRFVGTKWIDKLLPPIIIGPMIIVIGLGLAGSAVTNAGLVADGNW
                     KNALVAVVTFLIAAFINTKGKGFLRIIPFLFAIIGGYLFALTLGLVDFIPVLKANWFE
                     IPGFYLPFSTGGAFKEYNLYFGPEAIAILPIAIVTISEHIGDHTVLGQICGRQFLKEP
                     GLHRTLLGDGIATSVSAFLGGPANTTYGENTGVIGMTRIASVSVIRNAAFIAIALSFL
                     GKFTALISTIPNAVLGGMSILLYGVIASNGLKVLIKERVDFAQMRNLIIASAMLVLGL
                     GGAILKLGPVTLSGTALSAMTGIILNLILPYENKD"
     gene            complement(11624..12337)
                     /gene="rsmG"
                     /locus_tag="ACL3EZ_000479"
     CDS             complement(11624..12337)
                     /gene="rsmG"
                     /locus_tag="ACL3EZ_000479"
                     /EC_number="2.1.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005575 - cellular_component [Evidence
                     IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0031167 - rRNA methylation [Evidence IEA];
                     GO_process: GO:0046118 - 7-methylguanosine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HGR0392106.1"
                     /translation="MKPETFYNLLAEQNLPLSDQQKEQFERYFELLVEWNEKINLTAI
                     TDKEEVYLKHFYDSIAPILQGLIPNETIKLLDIGAGAGFPSLPMKILYPELDVTIIDS
                     LNKRINFLQLLAQELDLNGVHFYHGRAEDFAQDKNFRAQYDFVTARAVARMQVLSELT
                     IPYLKVGGKLLALKASNAPEELLEAKNALNLLFSKVEDNLSYALPNRDPRYITVVEKK
                     KETPNKYPRKAGMPNKRPL"
     gene            12431..12991
                     /locus_tag="ACL3EZ_000480"
     CDS             12431..12991
                     /locus_tag="ACL3EZ_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HGR0392107.1"
                     /translation="MTWIILGVIALIVIFVIVSYNGLVKNRMQTKEAWSQIDVQLKRR
                     NDLLPNLIETVKGYAKYEGSTLEKVAELRNQVAAATSPAEAMKASDALTRQVSGIFAV
                     AESYPDLKASANFVKLQEELTNTENKISYSRQLYNSVVSNYNVKLETFPSNIIAGMFG
                     FKAADFLQTPEEEKSVPKVDFSGLGD"
     gene            12993..13892
                     /gene="htpX"
                     /locus_tag="ACL3EZ_000481"
     CDS             12993..13892
                     /gene="htpX"
                     /locus_tag="ACL3EZ_000481"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease HtpX"
                     /protein_id="HGR0392108.1"
                     /translation="MLFDQIASNKRKTWILLLVFFLLLALVGYAVGYLFIRSGLGGLV
                     IALIIGFIYALSMIFQSTEIVMSMNGAREVDEQTAPDLYHVVEDMALVAQIPMPRVFI
                     IDDPALNAFATGSNPQNAAVAATSGLLAIMNREELEAVMGHEVSHIRNYDIRISTIAV
                     ALASAITMLSSMAGRMMWWGGAGRRRSDDDRDGNGLEIIMLVVSLLAIVLAPLAATLV
                     QLAISRQREFLADASSVELTRNPQGMINALDKLDNSKPMSRHVDDASSALYINDPKKG
                     GGFQKLFYTHPPISERIERLKHM"
     gene            complement(14041..15600)
                     /locus_tag="ACL3EZ_000482"
     CDS             complement(14041..15600)
                     /locus_tag="ACL3EZ_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGR0392109.1"
                     /translation="MHYRHSRKGNSMIKINHLTITQNKDLRDLVSDLSMTIQDGEKVA
                     IIGEEGNGKSTLLKTLMGEDLSDFTIKGDIQSDYQSLAYIPQKLPEELKKKTLHDYFF
                     LDSIDLDYSILYRLAEELHFDSNRFASDQEIGNLSGGEALKIQLIHELAKPFEILFLD
                     EPSNDLDLETVDWLKGQIQKTRQTVIFISHDEDFLSETADTIVHLRLVKHRKEAETLV
                     EHLDYDSYSEQRKANFAKQSQQAANNQRAYDKTMEKHRRVKQNVETALRATKDSTAGR
                     LLAKKMKTVLSQEKRYEKAAQSMTQKPLEEEQIQLFFSDIQPLPASKVLVQLEKENLS
                     IDDRVLVQKLQLTVRGQEKIGIIGPNGVGKSTLLAKLQRLLNDKREISLGFMPQDYHK
                     KLQLDLSPIAYLSKTGEKEELQKIQSHLASLNFSYPEMQHQIRSLSGGQQGKLLLLDL
                     VLRKPNFLLLDEPTRNFSPTSQPQIRKLFATYPGGLITVSHDRRFLKEVCSIIYRMTE
                     HGLKLVNLEDL"
     gene            complement(15839..16155)
                     /locus_tag="ACL3EZ_000483"
                     /pseudo
     CDS             complement(15839..16155)
                     /locus_tag="ACL3EZ_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389597.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
     gene            16324..16866
                     /locus_tag="ACL3EZ_000484"
     CDS             16324..16866
                     /locus_tag="ACL3EZ_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HGR0392110.1"
                     /translation="MKLNIQEIRKQSEGLNFEQTLDLVDDLRARNQEILDVKDILAVG
                     KVQYEDRMYFLDYQLSYTIVLASSRSMEPVELVESYPVTEVFMEGATNQLDQEVLDDD
                     LVLPIENGALDLAESVSDNILLNIPIKVLTAEEEAGQGFVSGNDWQIMTEEEYQAQQA
                     VKKEENSPFAGLQGLFDGDE"
     gene            16866..17495
                     /gene="nth"
                     /locus_tag="ACL3EZ_000485"
     CDS             16866..17495
                     /gene="nth"
                     /locus_tag="ACL3EZ_000485"
                     /EC_number="4.2.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140078 - class I DNA-(apurinic or
                     apyrimidinic site) endonuclease activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HGR0392111.1"
                     /translation="MVLSKKRARKVLEEIIALFPDAKPSLDFTNHFELLVAVMLSAQT
                     TDAAVNKATPGLFVAFPTPQAMSVATESEIASHISRLGLYRNKAKFLKKCAQQLLDDF
                     DGQVPQTREELESLAGVGRKTANVVMSVGFGIPAFAVDTHVERICKHHDIVKKSATPL
                     EVEKRVMDILPPEQWLAAHQAMIYFGRAICHPKNPECDQYPQLYDFSNL"
     gene            17706..18227
                     /gene="pyrR"
                     /locus_tag="ACL3EZ_000486"
     CDS             17706..18227
                     /gene="pyrR"
                     /locus_tag="ACL3EZ_000486"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HGR0392112.1"
                     /translation="MKTKEVVDELTVKRAITRITYEIIERNKDLNKIVLAGIKTRGVF
                     IAHRIQERLKQLENLSVPVVELDTKPFRDDVKSGEDTSLVSVDVTDREVILVDDVLYT
                     GRTIRAAIDNIVGHGRPARVSLAVLVDRGHRELPIRPDYVGKNIPTSRSEEIIVEMTE
                     LDDQDRVLITEEA"
     gene            18246..19169
                     /locus_tag="ACL3EZ_000487"
     CDS             18246..19169
                     /locus_tag="ACL3EZ_000487"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004070 - aspartate carbamoyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0016597 - amino acid binding [Evidence
                     IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HGR0392113.1"
                     /translation="MSENQQALNHVVSMEDLTVDQVMKLIKRGIEFKNGAQLPYEDHP
                     IVSNLFFEDSTRTHKSFEVAEIKLGLERLDFDVKTSSVNKGETLYDTILTLSALGVDV
                     CVIRHPEVDYYRELIASPTITTSIINGGDGSGQHPSQSLLDLMTIYEEFGHFEGLKVA
                     IAGDLDHSRVAKSNMQILKRLGAELFFAGPEEWRSQEFADYGQFVTIDEIIDQVDVMM
                     FLRVQHERHDSGAVFSKEDYHAQHGLTQERYDRLKETAILMHPAPINRDVEIADHLVE
                     APKSRIVQQMTNGVFVRMAILESVLASRNAN"
     gene            19219..20298
                     /locus_tag="ACL3EZ_000488"
     CDS             19219..20298
                     /locus_tag="ACL3EZ_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004088 - carbamoyl-phosphate synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006541 - glutamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl phosphate synthase small subunit"
                     /protein_id="HGR0392114.1"
                     /translation="MTKRILVLEDGTVFEGKAFGADIDVTGEIVFNTGMTGYQESITD
                     QSYNGQILTFTYPLVGNYGINRDDYESIIPTCKGVVVFEEARRASNWRNQMTLDEFLK
                     AKKIPGISGIDTRALTKIIRKHGTMRATLTHVGDSMDHVTDQLQATVLPTDNIKQVST
                     KTSYPAPGVGLSVVLVDFGLKHSILRELSKRNCNVTVVPYSTTAEEILHLNPDGVMLS
                     NGPGNPEDVPQALDMIRGVQGKIPIFGICMGHQLFAMANGAKTYKMKFGHRGFNHAVR
                     EIATGRVDFTSQNHGYAVSREDLPEHLIITHEEINDKSVEGVRHRYQPAFSVQYHPDA
                     APGPHDASYLFDEFIEMMEVFKQSN"
     gene            20610..23786
                     /gene="carB"
                     /locus_tag="ACL3EZ_000489"
     CDS             20610..23786
                     /gene="carB"
                     /locus_tag="ACL3EZ_000489"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HGR0392115.1"
                     /translation="MPKRTDIQKIMVIGSGPIIIGQAAEFDYAGTQACLSLKEEGYEV
                     VLVNSNPATIMTDKEIADKVYIEPITLEFVTRILRKERPDALLPTLGGQTGLNMAMEL
                     SKNGILDELGVELLGTKLSAIDQAEDRDLFKQLMEELEQPIPESEIVNTVEEAVAFAA
                     TIGYPVIVRPAFTLGGTGGGMCANEKELREITENGLKLSPVTQCLIERSIAGFKEIEY
                     EVMRDSADNALVVCNMENFDPVGIHTGDSIVFAPAQTMSDYENQMLRDASLSIIRALK
                     IEGGCNVQLALDPNSFKYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEV
                     INPVTGSTYAMFEPALDYVVAKIPRFPFDKFEKGERRLGTQMKATGEVMAIGRNIEES
                     LLKACRSLEIGVHHNEIPELAAVSDDALIEKVVKAQDDRLFYVSEAIRRGYTPEEIAE
                     LTKIDIFYLDKLLHIFEIEQELGAHPQDLEVLKTAKLNGFSDRKIAELWGTTDDQVRQ
                     LRLENKIVPVYKMVDTCAAEFDSETPYFYSTYGWENESIRSDKESVLVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQAAGYEAIIMNSNPETVSTDFSVSDKLYFEPLTFEDVMNVIDL
                     EQPKGVIVQFGGQTAINLAEPLAKAGVTILGTQVADLDRAEDRDLFEQALKELDIPQP
                     PGQTATNEEEAALAARKIGFPVLVRPSYVLGGRAMEIVENEEDLRSYMRTAVKASPDH
                     PVLVDSYIVGQECEVDAISDGKDVLIPGIMEHIERAGVHSGDSMAVYPPQTLSQKVQE
                     TIADYTKRLAIGLHCLGMMNIQFVIKDEKVYVIEVNPRASRTVPFLSKVTNIPMAQVA
                     TKLILGQSLSELGYQNGLYPESTRVHIKAPVFSFTKLAKVDSLLGPEMKSTGEVMGSD
                     ATLEKALYKAFEASYLHLPTFGNVVFTIADDAKEEALNLARRFQNIGYGILATEGTAA
                     FFASHGLQAQPVGKIGDDDKDIPSFVRKGRIQAIINTVGTKRTADEDGEQIRRSAIEH
                     GVPLFTALDTANAMLKVLESRSFVTEAI"
     gene            complement(24061..24870)
                     /locus_tag="ACL3EZ_000490"
     CDS             complement(24061..24870)
                     /locus_tag="ACL3EZ_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HGR0392116.1"
                     /translation="MQYLEKKEIKEIQLALLDYIDETCKKHDIPYFLSYGTMLGAIRH
                     KGMIPWDDDIDISLYREDYERLLKIIEEENHPRYKVLSYDTSSWYFHNFASILDTSTV
                     IEDHVKYKRHDTSLFIDVFPIDRFTDLSIVDKSYKYVALRQLAYIKKSRAVHGDSKLK
                     DFLRLCSWYALRFVNPRYFYKKIDQLVKNAVTNIPQYEGGVGIGKEGMKEIFPVDTFK
                     ELILTEFEGRMLPVPKKYDQFLTQMYGDYMTPPSKEMQEWYSHSIKAYRKN"
     gene            complement(24872..25675)
                     /locus_tag="ACL3EZ_000491"
     CDS             complement(24872..25675)
                     /locus_tag="ACL3EZ_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HGR0392117.1"
                     /translation="MKQLTVEDAKQIELEILDYIDTLCKKHNINYIINYGTLIGAVRH
                     EGFIPWDDDIDLSMPREDYQRFINIFQKEKSKYELLSLETDKNYFNNFIKITDSTTKI
                     IDTRNTKTYESGIFIDIFPMDRFDDPKVIDTCYKLESFKLLSFSKHKNIVYKDSLLKD
                     WIRTAFWLLLRPVSPRYFANKIEKEIQKYSRENGQYMAFIPSKFKEKEVFPSGTFDKT
                     IDLPFENLSLPAPEKFDTILTQFYGDYMTLPPEEKRFYSHEFHAYKLED"
     gene            complement(25685..27172)
                     /gene="tacF"
                     /locus_tag="ACL3EZ_000492"
     CDS             complement(25685..27172)
                     /gene="tacF"
                     /locus_tag="ACL3EZ_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV teichoic acid flippase TacF"
                     /protein_id="HGR0392118.1"
                     /translation="MKSIKLNALSYMGIRVLNIIFPILTGTYVARVLDRTDYGYFNSV
                     DTILSFFLPFATYGVYNYGLRAISNVKDNKKDLNRTFSSLFYLCIACTILTTAVYILA
                     YPLFFTDNPIIKKVYLVMGIQLIAQIFSIEWVNEALENYSFLFYKTAFIRILMLVSIF
                     LFVKNEHDIVVYTLVMSLSTLINYLISYFWIKRDIKLVKIHLSDFKPLFLPLTAMLVF
                     ANANMLFTFLDRLFLVKTGIDVNVSYYTIAQRIVTVIAGVVTGAIGVSVPRLSYYLGK
                     GDKEAYVSLVNRGSRIFNFFIIPLSFGLMVLGPNAILLYGSEKYIGGGILTSLFAFRT
                     IILALDTILGSQILFTNGYEKRITVYTVFAGLLNLGLNSLLFFNRIVAPEYYLLTTML
                     SEASLLVFYIIFIHRKQLIHLGHIFSYTVRYSLFSLSFVAIYFLINFVYPVDMVINLP
                     FLINTGLIILLSAISYISLLVFTKDSIFYEFLNHVLALKNKFKKS"
     gene            27508..28215
                     /locus_tag="ACL3EZ_000493"
     CDS             27508..28215
                     /locus_tag="ACL3EZ_000493"
                     /EC_number="2.7.7.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050518 - 2-C-methyl-D-erythritol
                     4-phosphate cytidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0019288 - isopentenyl diphosphate
                     biosynthetic process, methylerythritol 4-phosphate pathway
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HGR0392119.1"
                     /translation="MIYAGILAGGTGTRMGISNLPKQFLELGDRPILIHTIEKFVLEP
                     SIEKIVVGVHGDWVSHAEDLVDKYLPLYKERIIITKGGADRNTSIKNIIEAIDAYRPL
                     TPEDIVVTHDSVRPFITLRMIQDNIQLAQNHDAVDTVVEAVDTIVESTNGQFITDIPN
                     RAHLYQGQTPQTFRCKDFMDLYGSLSDEEKEILTDACKIFVIKGKDVALAKGEYSNLK
                     ITTVTDLKIAKSMIEKD"
     gene            28220..29242
                     /locus_tag="ACL3EZ_000494"
     CDS             28220..29242
                     /locus_tag="ACL3EZ_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribitol-5-phosphate dehydrogenase"
                     /protein_id="HGR0392120.1"
                     /translation="MINQIYQLTKPKFINVKYQEEAIDQENHILIRPNYMAVCHADQR
                     YYQGKRDPKILNKKLPMAMIHESCGTVISDPTGTYEVGQKVVMIPNQSPMQSDEEFYE
                     NYMTGTHFLSSGFDGFMREFVSLPKDRVVAYDAIEDTVAAITEFVSVGMHAMNRLLTL
                     AHSKRERIAVIGDGSLAFVVANIINYTLPEAEIVVIGRHWEKLELFSFAKECYITDNI
                     PEDLAFDHAFECCGGDGTGPAINDLIRYIRPQGTILMMGVSEYKVNLNTRDALEKGLL
                     LVGSSRSGRIDFENAIQMMEVKKFANRLKNILYLEEPVREIKDIHRVFATDLNTAFKT
                     VFKWEV"
     gene            29259..30128
                     /gene="licA"
                     /locus_tag="ACL3EZ_000495"
     CDS             29259..30128
                     /gene="licA"
                     /locus_tag="ACL3EZ_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline kinase LicA"
                     /protein_id="HGR0392121.1"
                     /translation="MEKIIKEKISSLLSQEEEVLSVEQLGGMTNQNYLAKTTNKQYIV
                     KFFGKGTEKLINRQDEKYNLELLKDLGLDVKNYLFDIEAGIKVNEYIGSAITLDSTSI
                     KTKFDKIAPILQTIHTSAKELRGEFAPFEEIKKYESLIEEQIPYANYESVRNAVFSLE
                     KRLADLGVDRKSCHIDLVPENFIESPQGRLYLIDWEYSSMNDPMWDLAALFLESEFTS
                     QEEETFLSHYESEQTPVSHEKIAIYKILQDTIWSLWTVYKEEQGADFGDYGVNRYQRA
                     VKGLASYGGSDEK"
     gene            30118..30996
                     /locus_tag="ACL3EZ_000496"
     CDS             30118..30996
                     /locus_tag="ACL3EZ_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HGR0392122.1"
                     /translation="MKSKNGVPFGLLSGIFWGLGLTVSAYIFSIFTDLSPFVVAATHD
                     FLSIFILLAFLLVKEGKVRLSIFLNIRNVSVIIGALLAGPIGMQANLYAVKYIGSSLA
                     SSVSAIYPAISVLLAFFFLKHKISKNTVFGIVLIIGGIIAQTYKVEQVNSFYIGILCA
                     LVCAIAWGSESVLSSFAMESELSEIEALLIRQVTSFLSYLVIVLFSHQSFTAVANGQL
                     LGLMIVFAAFDMISYLAYYIAINRLQPAKATGLNVSYVVWTVLFAVVFLGAPLDMLTI
                     MTSLVVIAGVYIIIKE"
     gene            31008..31697
                     /locus_tag="ACL3EZ_000497"
     CDS             31008..31697
                     /locus_tag="ACL3EZ_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate nucleotidyltransferase"
                     /protein_id="HGR0392123.1"
                     /translation="MKAIILAAGLGTRLRPMTENTPKALVQVNQKPLIEYQIEFLKEK
                     GINDIIIIVGYLKEQFDYLKEKYGVRLVFNDKYADYNNFYSLYLVKEELANSYVIDAD
                     NYLFKNMFRNDLTRSTYFSVYREDCTNEWFLVYGDDYKVQDIIVDSKAGRILSGVSFW
                     DAPTAEKIVSFIDKAYVSGEFVDLYWDNMVKDNIKELDVYVEELEGNSIYEIDSVQDY
                     RKLEEILKNEN"
     gene            31793..32641
                     /gene="dprA"
                     /locus_tag="ACL3EZ_000498"
     CDS             31793..32641
                     /gene="dprA"
                     /locus_tag="ACL3EZ_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009294 - DNA-mediated transformation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-processing protein DprA"
                     /protein_id="HGR0392124.1"
                     /translation="MKITNYEIYKLKKSGLTNQQILKVLEYGENVDQELLLGDIADIS
                     GCRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDCYPWDLSEIYDAPVLLFYKGNLD
                     LLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
                     TIAVIGTGLDVFYPKANKRLQDYIGNDHLVLSEYGPGEQPLKFHFPARNRIIAGLCRG
                     VIVAEAKMRSGSLITCERAMEEGRDVFAIPGSILDGLSDGCHHLIQEGAKLVTSGQDV
                     LAEFEF"
     gene            33530..34573
                     /locus_tag="ACL3EZ_000499"
     CDS             33530..34573
                     /locus_tag="ACL3EZ_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00341 family protein"
                     /protein_id="HGR0392125.1"
                     /translation="MTNNKLYSLIEFRNKIYEELELSRSDLAILLCAMLIASIGLNMD
                     STPVIIGAMLISPLMTPILGVGLSLAIFDFKLLRKSFKILAIQILASLIASTLYFYLS
                     PISYASSEIVARTSPTIWDVLIAFVGGIAGIIGARKKETNNIVPGVAIATALMPPLCT
                     VGYAIASANLKFIIGSSYLFLINCSFIVIATYIGVRLMMVKKHYFKDNEEDSKMRRIL
                     LLVAVLLMIPSFISATTLVRETLKKESLKKFISEQFQEYNILKKTYSKKTHTLKLTIS
                     GNYLTEEELDMISSKRGDYGLSDVSVQVSQLSDSEQLSKEELVEYFFQYIKDKEAKEK
                     EKANKFDTESEEQ"
     gene            34740..36827
                     /gene="topA"
                     /locus_tag="ACL3EZ_000500"
     CDS             34740..36827
                     /gene="topA"
                     /locus_tag="ACL3EZ_000500"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HGR0392126.1"
                     /translation="MATATKKKKSTVKKNLVIVESPAKAKTIEKYLGRNYKVLASVGH
                     IRDLKKSSMSVDIENNYEPQYINIRGKGPLINDLKKEAKKANKVFLASDPDREGEAIS
                     WHLAHILNLDENDANRVVFNEITKDAVKNAFKEPRKIDMDLVDAQQARRILDRLVGYS
                     ISPILWKKVKKGLSAGRVQSIALKLIIDRENEINAFQPEEYWTVDAVFKKGTKQFHAS
                     FYGVDGKKMKLTSNNEVKEVLSRLTSKDFSVDQVDKKERKRNAPLPYTTSSMQMDAAN
                     KINFRTRKTMMVAQQLYEGINIGSGVQGLITYMRTDSTRISPVAQNEAASFITDRFGS
                     KYSKHGSKVKNASGAQDAHEAIRPSSVFNTPESIAKYLDKDQLKLYTLIWNRFVASQM
                     TAAVFDTMAVKLSQNGVQFAANGSQVKFDGYLAIYNDSDKNKMLPDMVVGDVVKQVNS
                     KPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTIETIQKRYYVRLAAKRFEPTEL
                     GEIVNKLIVEYFPDIVNVTFTAEMEGKLDDVEVGKEQWRRVIDAFYKPFSKEVAKAEE
                     EMEKIQIKDEPAGFDCEVCGSPMVIKLGRFGKFYACSNFPDCRHTQAIVKEIGVECPS
                     CHQGQIIERKTKRNRLFYGCNRYPECEFTSWDKPVGRDCPKCGNFLMEKKVRGGGKQV
                     VCSKGDYEEEKIK"
     gene            36933..37292
                     /locus_tag="ACL3EZ_000501"
     CDS             36933..37292
                     /locus_tag="ACL3EZ_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YbaN family protein"
                     /protein_id="HGR0392127.1"
                     /translation="MRLIYLIIGFLSLALAIVGVVLPLLPTTPFLLLSIACFSRSSKR
                     FEDWLYHTKLYQTYVADFRETKSITRERKKKIIVSIYILMGISIYFAPLLPVKIGLGA
                     LTIFITYYLFKVIPDKE"
     gene            37385..38017
                     /locus_tag="ACL3EZ_000502"
     CDS             37385..38017
                     /locus_tag="ACL3EZ_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005507 - copper ion binding [Evidence
                     IEA];
                     GO_process: GO:0055070 - copper ion homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HGR0392128.1"
                     /translation="MIYEFCAENVTLLEKAMQAGARRIELCDNLAVGGTTPSYGVTKA
                     AVELAANYDTTIMTMIRPRGGDFVYNDLEIAIMLEDICLTAQAGSQGVVFGALTADKK
                     LDKPNLEKLIAASKGMEIVFHMAFDELSDEDQPEAIDWLSQAGVTRILTRAGVSGDSL
                     EKRFVHYHRILEYAKGKIEILPGGGIDLDNRQTFIDQVGVTQLHGTKVVF"
     gene            38061..38717
                     /locus_tag="ACL3EZ_000503"
     CDS             38061..38717
                     /locus_tag="ACL3EZ_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HGR0392129.1"
                     /translation="MFEIFKSYQFNQEKAHDYGFIENSEVWTYSCQILQGDFVMTVSI
                     TADNVNFQVFDQETGDLYPHVHMESMRGSFVGNVREACLEILYQIRKACFDVQDFICH
                     QTKRIMTQVQEKYGNQLEYLWEKSPDTAVLRHEGNQKWYAVLMKISWNKLEKGREGQV
                     EAVNLKHDQVANLLSQKGIYPAFHMSKRYWISVSLDDTLSDEEVLELIEKSWNLTSKK
                     "
     gene            38787..39830
                     /locus_tag="ACL3EZ_000504"
                     /pseudo
     CDS             38787..39830
                     /locus_tag="ACL3EZ_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261078.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003852 - 2-isopropylmalate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009098 - L-leucine biosynthetic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-isopropylmalate synthase regulatory
                     domain-containing protein"
     gene            39842..40879
                     /gene="leuB"
                     /locus_tag="ACL3EZ_000505"
     CDS             39842..40879
                     /gene="leuB"
                     /locus_tag="ACL3EZ_000505"
                     /EC_number="1.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003862 - 3-isopropylmalate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0009098 - L-leucine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
                     /protein_id="HGR0392130.1"
                     /translation="MAKKIVALVGDGIGPEIMEAGLEVLEALAEKTGFDYEIDRRPFG
                     GADIDAAGPPLPDETLKASREADAILLAAIGSPQYDGAAVRPEQGLMALRKELNLYAN
                     IRPVKIFDSLKYLSPLKPERISGVDFVVVRELTGEIYFGDHILEERKARDINDYSYEE
                     VERIIRKAFEIARNRRKIVTSIDKQNVLATSKLWRKVAEEVAQDFPDVTLEHQLVDSA
                     AMLMITNPAKFDVIVTENLFGDILSDESSVLSGTLEVMPSASHSENGPSLYEPIHGSA
                     PDIAGQGIANPTSMILSVAMMLRDSFGRYEDAERIKHAVETSLAAGILTRDIGGQAST
                     KEMTEAIIARL"
     gene            40876..41145
                     /locus_tag="ACL3EZ_000506"
     CDS             40876..41145
                     /locus_tag="ACL3EZ_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HGR0392131.1"
                     /translation="MKLDEKITLVLLIWNVIIFLIYGIDKFKARRRTWRIQEKILLIL
                     ALTCGGFGAWLAGITFHHKTRKWYFKTVWFLGMVTTLVALYFIWR"
     gene            41149..41508
                     /gene="leuD"
                     /locus_tag="ACL3EZ_000507"
     CDS             41149..41508
                     /gene="leuD"
                     /locus_tag="ACL3EZ_000507"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009316 - 3-isopropylmalate dehydratase
                     complex [Evidence IEA];
                     GO_function: GO:0003861 - 3-isopropylmalate dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009098 - L-leucine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HGR0392132.1"
                     /translation="MAGSSREHAAWVLADYGFKVVIAGSFGDIHYNNELNNGLLPIVQ
                     PREVREKLAQLKPTDQVTVDLEQQKIISPVEEFTFEIDSEWKHKLLNSLDDIGITLQY
                     EELIAAYEKQRPAYWQD"
     gene            41670..42293
                     /locus_tag="ACL3EZ_000508"
                     /pseudo
     CDS             41670..42293
                     /locus_tag="ACL3EZ_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004899133.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003725 - double-stranded RNA binding
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Sua5/YciO/YrdC/YwlC family protein"
     gene            42459..44372
                     /locus_tag="ACL3EZ_000509"
     CDS             42459..44372
                     /locus_tag="ACL3EZ_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrB family protein"
                     /protein_id="HGR0392133.1"
                     /translation="MNKRKVSLEDFYKWYSLNKEELLNKATVGEKFNDKLKEEFLQEW
                     PLDRILTMSIDEYVIGKGQQNKSLCYALEKGKYKNLFLGISGGSASKFGIYWNKKTNK
                     YKDQANNEISELDQRFSKLKSDLYEIIKEGIRFNFENPIFDMKRSTNEFIGRSAMVTK
                     LLCIYTEGDPFFGVNINSQKEFWNHFVSQTNQGGPYLQNHKIIELVSKTYPELEPSKL
                     GTMLFEYSKLFMENKEDNSTMDSSNNFRHQLTQSLLKSPNLILRGAPGTGKTYLAKEI
                     AKELTDGNEDQIGFVQFHPSYDYTDFVEGLRPVSNGDGAIEFRLQDGIFKDFCQKAKE
                     TQLIGGQDNFDEAWDSYLEYINVAEEKEYITKTSYLSINSRQNLSVNYDSGVSGWSLP
                     SKYVYELYKDKNYNKQEYYKSGGKTVLETLRKRFGLKDYVSPTEIDTDKKFVFIIDEI
                     NRGEISKIFGELFFSIDPGYRGEKGSVSTQYANLHETDEKFYIPENVYIIGTMNDIDR
                     SVDTFDFAMRRRFRFVEVTAEGQVGMLDKELNIHAEEAKIRLRNLNAAIENVQELNSH
                     YHIGPSYFLKLKDVDFDYELLWSDYIKPLLEDYLRGSYDEVETLETLKKAFELTNNDQ
                     TGQQDTGDNDADY"
     gene            44359..45675
                     /locus_tag="ACL3EZ_000510"
     CDS             44359..45675
                     /locus_tag="ACL3EZ_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001223073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrC family protein"
                     /protein_id="HGR0392134.1"
                     /translation="MRITDNQYKIIKEKFVEEYPKLSNLLLDRTLESLSQDERIFIFP
                     NDLTHTPDLDKDQKIFETVNQKIKTGNVIGFLGYGQERLTISSRFSDESNDHFLHYLL
                     NKVLHINLTSLDVALSREERLYQLLMYLFPKYLQAAIRKGLYKEYQRFSHNDSHVKGV
                     IDVRNHLKKNLPFTGNIAYTTREFTYDNPLMQLVRHTIEYIKNQKSIGQGVLDNLSTS
                     RENVSEIVRVTPSYKLADRAKIIRGNQSKPIRHAYFHEYRNLQELCLMILNQEKHGLG
                     YQDQKIYGILFDVAWLWEEYVYTLLPKGFVHPRNKDKTDGISVFSVGKRKVYPDFYDR
                     ERKIVLDAKYKKLELTEKGINREDLFQLISYSYILKAEKAGLVFPSKDKVIDNEMGNL
                     AGYGALLKKWSIQIPQKSSSYSAFCKMMENSEENFKAIIDEEVGRK"
     gene            45850..46836
                     /locus_tag="ACL3EZ_000511"
     CDS             45850..46836
                     /locus_tag="ACL3EZ_000511"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902560 - GMP reductase complex [Evidence
                     IEA];
                     GO_function: GO:0003920 - GMP reductase activity [Evidence
                     IEA];
                     GO_process: GO:0006163 - purine nucleotide metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HGR0392135.1"
                     /translation="MLNEFPIFDYEDIQLIPNKCVIKSRAEADTSVTLGNHTFKLPVV
                     PANMQTILDENVAEQLAKGGYFYIMHRFDEAGRIPFIKRMHDQGLIASISVGVKDYEY
                     DFVRQLKTDAPEYITIDIAHGHADSVISMIQHIKKELPDTFVIAGNVGTPEAVRELEN
                     AGADATKVGIGPGKVCITKVKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIA
                     KSIRFGASMIMIGSLFAGHIESPGKTIEVDGEQFKEYYGSASQYQKGAYKNVEGKRIL
                     LPAKGHLQDTLTEMEQDLQSAISYAGGRQVADLKHVDYVIVKNSIWNGDASH"
     gene            46900..46971
                     /locus_tag="ACL3EZ_000512"
     tRNA            46900..46971
                     /locus_tag="ACL3EZ_000512"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:46933..46935,aa:Arg,seq:ccg)
     gene            47154..47852
                     /gene="rnc"
                     /locus_tag="ACL3EZ_000513"
     CDS             47154..47852
                     /gene="rnc"
                     /locus_tag="ACL3EZ_000513"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004525 - ribonuclease III activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HGR0392136.1"
                     /translation="MKELQTVLKNHFAIEFTDKNLLETAFTHTSYANEHRLLKISHNE
                     RLEFLGDAVLQLLISEYLYKKYPKKPEGDLSKLRAMIVREESLAGFARDCQFDQFIKL
                     GKGEEKSGGRNRDTILGDAFEAFLGALLLDKDVAKVKEFIYQVMIPKVEAGEFEMITD
                     YKTYLQELLQVNGDVAIRYQVISETGPAHDKVFDVEVLVEGKSIGQGQGRSKKLAEQE
                     AAKNAVEKGLDSCI"
     gene            47843..51382
                     /gene="smc"
                     /locus_tag="ACL3EZ_000514"
     CDS             47843..51382
                     /gene="smc"
                     /locus_tag="ACL3EZ_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA];
                     GO_process: GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HGR0392137.1"
                     /translation="MYLKEIEIQGFKSFADKTKVVFDQGVTAVVGPNGSGKSNITESL
                     RWALGESSVKSLRGGKMPDVIFAGTESRKPLNYASVVVTLDNHDGFIKDAGQEIRVER
                     HIYRSGDSEYKIDGKKVRLRDIHDLFLDTGLGRDSFSIISQGKVEEIFNSKSEERRAI
                     FEEAAGVLKYKTRRKETESKLQQTQDNLDRLEDIIYELDNQIKPLEKQAENARKFLDL
                     EGQRKAIYLDVLVAQIKENKAELESTEEELAQVQELLMSYYQKREKLEEENQTLKKQR
                     QDLQDEMAKDQGSLMDLTSLISDLERKLALSKLESEQVALNQQEAQARLAALEDKRNS
                     LSKEKYDKESSLALLEGNLVQNNQKLNRLEAELLAFSDDPDQMIELLRERFVALLQEE
                     ADVSNQLTRIENELENSRQLSQKQADQLEKLKEQLAIAKEKASQQKEELETAKEQVQK
                     LLADYQAIAKEQEEQKTSYQAQQSQLFDRLDNLKNKQARAQSLENILRNHSNFYAGVK
                     SVLQEKDRLGGIIGAVSEHLTFDVYYQTALEIALGASSQHIIVEDEESATKAIDFLKR
                     NRAGRATFLPLTTIKARTISSQNQDAIAVSPGFLGMADELVTFDTRLEAIFKNLLATT
                     AIFDTVEHARAAARQVRYQVRMVTLDGTELRTGGSYAGGANRQNNSIFIKPELEQLQK
                     EIAEEEASLRSDEVSLKNLQDELARLTERLEAIKSQGEQARIQEQGLSLAYQQTSQQV
                     EELETLWKLQEEEIDRLSEGDWQADKEKCQERLAAIASDKQNLEAEIEEIKSNKNAIQ
                     ERYQNLQEELAQARLLKTELQGQKRYEVADIERLGKELDNLDFEQEEIQRLLQEKVDN
                     LEKVDTELLSQQAEESKTQKTNLQQGLIRQQFELDDIEGQLDDIASHLDQARQQNEEW
                     IRKQTRAEAKKEKVSERLRHLQSQLTDQYQISYTEALEKAHELENLNLAEQEVKDLEK
                     AIRSLGPVNIEAIDQYEEVHNRLDFLNSQRDDILSAKNLLLETITEMNDEVKERFKST
                     FEAIRESFKVTFKQMFGGGQADLILTEGDLLTAGVEISVQPPGKKIQSLNLMSGGEKA
                     LSALALLFSIIRVKTIPFVILDEVEAALDEANVKRFGDYLNRFDKDSQFIVVTHRKGT
                     MAAADSIYGVTMQESGVSKIVSVKLKDLESIEG"
     gene            51379..52173
                     /locus_tag="ACL3EZ_000515"
     CDS             51379..52173
                     /locus_tag="ACL3EZ_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HGR0392138.1"
                     /translation="MTIKLVATDMDGTFLDGNGRFDMDRLKSLLASYKEKGIYFAVAS
                     GRGFLSLEKLFAGVRDDIIFIAENGSLVEYQGQDLYEATMSRDFYLATFEKLKTSPYV
                     DINKLLLTGKKGSYVLDTVDETYLKVSQHYNENIQKVASLEDITDDIFKFTTNFTEET
                     LEAGEAWVNDNVPGVKAMTTGFESIDIVLDYVDKGVAIVELAKKLGITMDQVMAFGDN
                     LNDLHMMQVVGHPVAPENARPEILELAKTVIGHHKERSVIAYMEGL"
     gene            52173..52991
                     /locus_tag="ACL3EZ_000516"
     CDS             52173..52991
                     /locus_tag="ACL3EZ_000516"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HGR0392139.1"
                     /translation="MADIKLIALDLDGTLLTTDKRLTDRTKETLKAARDRGIKVVLTT
                     GRPLKAMDFFLHELGTDGQEDEYTITFNGGLVQKNTGEILDKTVFSYDDVARLYEKTE
                     KLSLPLDAISEGTVYQIQSDQESLYAKFNPALTFVPVDFEDLSSQMTYNKCVTAFAQE
                     PLDAAIQKISPELFDQYEIFKSREMLLEWSPKNVHKATGLAKLISHLGINQSQVMACG
                     DEANDLSMIEWAGLGVAMQNAVPEVKAAANVVMPMTNDEEAVAWAIEEYVLKEN"
     gene            52995..54284
                     /gene="ftsY"
                     /locus_tag="ACL3EZ_000517"
     CDS             52995..54284
                     /gene="ftsY"
                     /locus_tag="ACL3EZ_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005047 - signal recognition particle
                     binding [Evidence IEA];
                     GO_process: GO:0006614 - SRP-dependent cotranslational
                     protein targeting to membrane [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HGR0392140.1"
                     /translation="MGLFDRLFGKKEEPKIEEVVKEALENLDLSEDVDPTFTEVEEVP
                     QEEAEVEIVEQAVFQEEEIQDTVEESQDSEPAVGVSQEEIEELPNSEELPEEEKLEHE
                     GTVEENNSEVLEPERPQTEETVQEKYDRSLKKTRTGFGARLNAFFANFRSVDEEFFEE
                     LEELLIMSDVGVQVASNLTEELRYEAKLENAKKPDALRRVIIEKLVELYEKDGSYDES
                     IHFQDNLTVMLFVGVNGVGKTTSIGKLAHRYKRTGKKVMLVAADTFRAGAVAQLAEWG
                     RRVDVPVVTGPEKADPASVVFDGMERAVAEGIDILMIDTAGRLQNKDNLMAELEKIGR
                     IIKRVVPEAPHETFLALDASTGQNALVQAKEFSKITPLTGIVLTKIDGTARGGVVLAI
                     REELNIPVKLIGFGEKIDDIGEFNSENFMKGLLEGLI"
     gene            complement(54328..55815)
                     /gene="zwf"
                     /locus_tag="ACL3EZ_000518"
     CDS             complement(54328..55815)
                     /gene="zwf"
                     /locus_tag="ACL3EZ_000518"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004345 - glucose-6-phosphate
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016614 - oxidoreductase activity, acting
                     on CH-OH group of donors [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HGR0392141.1"
                     /translation="MSSKVIVTIFGASGDLAKRKLYPSLFRLYKSGNLSKHFAVIGTA
                     RRPWSKEYFESVVVESILDLADSTEQAQEFASHFYYQSHDVNDSEHYIALRQLQAELN
                     EKYQAEHNKLFFLSMAPQFFGTIAKHLKSENIVDGKGFERLIVEKPFGTDYATASKLN
                     DELLATFDEEQIFRIDHYLGKEMIQSIFAVRFANLIFENVWNKDFIDNVQITFAERLG
                     VEERGGYYDQSGALRDMVQNHTLQLLSLLAMDKPASFTKDEIRAEKIKVFKNLYHPTD
                     EELKEHFIRGQYRSGKIDGMKYISYRSEPNVNPESTTETFTSGAFFVDSDRFRGVPFF
                     FRTGKRLTEKGTHVNIVFKQMDSIFGEPLAPNILTIYIQPTEGFSLSLNGKQVGEEFN
                     LAPNSLDYRTDATATGASPEPYEKLIYDVLNNNSTNFSHWDEVGASWKLIDRIEELWA
                     ENGAPLHDYKAGSMGPQASFDLLEKFDAKWTWQPDIAYRQDGRFE"
     gene            complement(55964..56704)
                     /locus_tag="ACL3EZ_000519"
     CDS             complement(55964..56704)
                     /locus_tag="ACL3EZ_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HGR0392142.1"
                     /translation="MAKLKIDVNDLHKHYGKNEVLKGITTKFYEGDVVCIIGPSGSGK
                     STFLRSLNLLEEVTSGHITVNGYDLTEKTTNVDHVRENIGMVFQHFNLFPHMSVLDNI
                     TFAPIEHKLMTKEEAEELGMELLEKVGLADKANANPDSLSGGQKQRVAIARGLAMNPD
                     IMLFDEPTSALDPEMVGDVLNVMKELAEQGMTMIIVTHEMGFARQVANRVIFTADGEF
                     LEDGTPDQIFDNPQHPRLKEFLDKVLNV"
     gene            complement(56704..58869)
                     /locus_tag="ACL3EZ_000520"
     CDS             complement(56704..58869)
                     /locus_tag="ACL3EZ_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HGR0392143.1"
                     /translation="MKKKFLAFLLILFPIFSLGIAKAETIKIVSDTAYAPFEFKDSDQ
                     TYKGIDVDIINKVAEIKGWNIQMSYPGFDAAVNAVQAGQADAIMAGMTKTKEREKVFT
                     MSDTYYDTKVVIATTKSHKISKYDQLTGKTVGVKNGTAAQRFLETIKDKYGFTIKTFD
                     TGDLMNNSLSAGAIDAMMDDKPVIEYAINQGQDLHIEMDGEAVGSFAFGVKKGSKYEH
                     LVTEFNQALSEMKKDGSLDKIIKKWTASSSSAVPTTTTLAGLKAIPVKAKYIIASDSS
                     FAPFVFQNSSNQYTGIDMELIKAIAKDQGFEIEITNPGFDAAISAVQAGQADGIIAGM
                     SVTDARKATFDFSESYYTANTILGVKESSNIASYEDLKGKTVGVKNGTASQTFLTENQ
                     SKYGYKIKTFADGSSMYDSLNTGAIDAVMDDEPVLKYSISQGQKLKTPISGTPIGETA
                     FAVKKGANPELIEMFNNGLANLKANGEFQKILDKYLASESSTASTSTVDETTLWGLLQ
                     NNYKQLLSGLGITLALALISFAIAIVIGIIFGMFSVSPYKSLRVISEIFVDVIRGIPL
                     MILAAFIFWGIPNFIESITGQQSPINDFVAGTIALSLNAAAYIAEIVRGGIQAVPVGQ
                     MEASRSLGISYGKTMRKIILPQATKLMLPNFVNQFVIALKDTTIVSAIGLVELFQTGK
                     IIIARNYQSFKMYAILAIFYLVIITLLTRLAKRLEKRIR"
     gene            59039..59992
                     /locus_tag="ACL3EZ_000521"
     CDS             59039..59992
                     /locus_tag="ACL3EZ_000521"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0071586 - CAAX-box protein processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane glutamic
                     endopeptidase"
                     /protein_id="HGR0392144.1"
                     /translation="MKNKRIFKDFQASKMSLNIYTSPLLAFVFVFIGEFVAFTLYGIG
                     LLALIGLARNFGEAGQNLASYLQTLHQSLTDKTSDFRLILGLLAFGFILNTVFRWTRK
                     VEKRPIRTLGFYRENFLSNLLKGFSLGLALFLLTLLGLVVLGQYRLESIHLNPYSLAF
                     VVFTIPFWILQGTAEEVVARAWLLPQLASRTNLKLAILISSLFFTLLHMGNSGLTPLS
                     LVNLFLFGVAMALYLLKTDTVWGVAGIHGAWNFAQGNLFGILVSGQPSGTSLMTFLPQ
                     GNQDWLSGGSFGIEGSIMTSLVLLLLIVYLANKLKKENERM"
     gene            60069..62057
                     /gene="uvrB"
                     /locus_tag="ACL3EZ_000522"
     CDS             60069..62057
                     /gene="uvrB"
                     /locus_tag="ACL3EZ_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009380 - excinuclease repair complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HGR0392145.1"
                     /translation="MINHITDNQFKLVSKYQPSGDQPQAIEQLVDNIEGGEKAQILMG
                     ATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYGEFKEFFPENAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYA
                     DSVVSLRPGLEISRDKLLNDLVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFR
                     VEFFGDEIDRIREVEALTGQVLGEVDHLAIFPATHFVTNDDHMEVAVAKIQAELEEQL
                     AVFEKEGKLLEAQRLKQRTEYDIEMLREMGYTNGVENYSRHMDGRSEGEPPYTLLDFF
                     PDDFLIMIDESHMTMGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVH
                     QIVYVSATPGDYENEQTETVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINARVEKN
                     ERTFITTLTKKMAEDLTDYFKEMGIKVKYMHSDIKTLERTEIIRDLRLGVFDVLVGIN
                     LLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADTVTQSMQ
                     RAIDETARRRKIQMAYNEEHGIVPQTIKKEIRDLIAVTKAVAKEEDKEVDINSLNKQE
                     RKELVKKLEKQMQEAVEVLDFELAAQIRDMMLEVKALD"
     gene            62068..62631
                     /locus_tag="ACL3EZ_000523"
     CDS             62068..62631
                     /locus_tag="ACL3EZ_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family protein"
                     /protein_id="HGR0392146.1"
                     /translation="MIYLRKLKKEDLMSLWEMAYSQLNPVWKQYDAPYYDDYQYFSNF
                     KEFELQKSESILSNSNRLGIFVDDKLVGTVSRYWVCKETRWMELGIGIYDKKFWNTGI
                     GKVAMLQWIDRTFQDYLELEHLVLTTWSGNLGMMKLAEKLRMKKEAHIPKVRYYQGKY
                     FDSIKYGILREDWEKINDGYYQINGNS"
     gene            62597..63085
                     /locus_tag="ACL3EZ_000524"
     CDS             62597..63085
                     /locus_tag="ACL3EZ_000524"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR0392147.1"
                     /translation="MTVIIKSMETPEEIEGKSLVHWQTWRESYDDLLPAEFQDTMTLE
                     RCRFFSQKYPENTLIAMDGVKVVGFISYGNFRDETIQAGEIIALYVLKDYYGKGIAQK
                     LMKAALTALNHFSEIFLWVLKDNKRAIAFYQKMGFTFDGQEKILELGKPIKEKRMVFY
                     SK"
     gene            63159..63626
                     /locus_tag="ACL3EZ_000525"
     CDS             63159..63626
                     /locus_tag="ACL3EZ_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HGR0392148.1"
                     /translation="MSRSQLTILTNICLIEDLETQRVVMQYRAPENNRWSGYAFPGGH
                     VENDEAFAESVIREIYEETGLTIQNPQLVGIKNWPLDTGGRYIVICYKATEFSGTLQS
                     SEEGEVSWVQKDQIPNLNLAYDMLPLMEMMEAPDKSEFFYPRRTEDDWEKKIF"
     gene            complement(63623..64138)
                     /locus_tag="ACL3EZ_000526"
     CDS             complement(63623..64138)
                     /locus_tag="ACL3EZ_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HGR0392149.1"
                     /translation="MTKDRKQALLQLLKEAPKALNGQSLAEHFHVTRQVIVQDIAILR
                     ADGAPILSTNRGYIYKQIDTNPYVHKLFKVKHEVEEIGQELLAIVDNGGHVQNTLIDH
                     PVYGEIETLLKLSCRRDVQHFLEQVEHSDFRPLSELTDGIHYHLVEAETQQDLHYIEE
                     ALDQLGYLVKD"
     gene            complement(64150..64677)
                     /locus_tag="ACL3EZ_000527"
     CDS             complement(64150..64677)
                     /locus_tag="ACL3EZ_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HGR0392150.1"
                     /translation="MNTRKKTQFMTMTALLTAIAILIPIVMPFKIVIPPASYTLGSHI
                     AIFIAMFLSPLMAVFVILASSFGFLMAGYPMVIVFRAFSHISFGALGALYLQKFPDTL
                     DKPKSSWVFNFVLAVVHALAEVLACVLFYATSGTNVENMFYVLFVLVGFGTIIHSMVD
                     YTLALAVYKVLRKRR"
     gene            complement(64959..65522)
                     /locus_tag="ACL3EZ_000528"
     CDS             complement(64959..65522)
                     /locus_tag="ACL3EZ_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HGR0392151.1"
                     /translation="MKKRSNIAPIAIFFATMLVIHFLSSLIFNLFPFPIKPTIVHIPV
                     IIASIIYGPRVGVTLGFLMGLLSLTVNTITILPTSYLFSPFVPNGNIYSAIIAIVPRI
                     LIGLTPYLVYKLMKNKTGLILAGALGSLTNTIFVLGGIFFLFGNVYNGNIQLLLATVI
                     STNSIAELVISAILTLAIVPRLQTLKK"
     gene            complement(65506..66057)
                     /gene="coaC"
                     /locus_tag="ACL3EZ_000529"
     CDS             complement(65506..66057)
                     /gene="coaC"
                     /locus_tag="ACL3EZ_000529"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004633 - phosphopantothenoylcysteine
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HGR0392152.1"
                     /translation="MANILLAVTGSIASYKSADLVSSLKKQGHQVTVLMTQAATEFIQ
                     PLTLQVLSQNPVHLDVMKEPYPDQVNHIELGKKADLFIVVPATANTIAKLAHGFADNM
                     VTSTALALPSHIPKLIAPAMNTKMYDHPVTQNNLKTLETYGYQLIAPKESLLACGDHG
                     RGALADLTIILERIKETIDEKTL"
     gene            complement(66069..66758)
                     /gene="coaB"
                     /locus_tag="ACL3EZ_000530"
     CDS             complement(66069..66758)
                     /gene="coaB"
                     /locus_tag="ACL3EZ_000530"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004632 - phosphopantothenate--cysteine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HGR0392153.1"
                     /translation="MKILVTSGGTSEAIDSVRSITNHSTGHLGKIITETLLSAGHEVC
                     LITTKRALKPEPHPNLSIREITNTKDLLIEMQERVQDYQVLIHSMAVSDYTPVYMTGL
                     EEVQASSNLKEFLSKQNHQAKISSTDEVQVLFLKKTPKIISLVKEWNPTIHLIGFKLL
                     VDVTEDHLVDIARKSLIKNQADLIIANDLTQISADQHRAIFVEKNQLQTVQTKEEIAE
                     LLLEKIQAYHS"
     gene            66988..68658
                     /locus_tag="ACL3EZ_000531"
     CDS             66988..68658
                     /locus_tag="ACL3EZ_000531"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004329 - formate-tetrahydrofolate ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HGR0392154.1"
                     /translation="MKTDIEIAQSIELKPIVDVVEKLGISYDDLELYGKYKAKLSFDK
                     IRAVESNPVGKLILVTAINPTPAGEGKSTLTIGLADALNKIGKKTMIAIREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALIDNHLHQGNELEIDQRR
                     ILWKRVVDLNDRALRHVTVGLGGPLNGIPREDGFDITVASEIMAILCLATDIEDLKRR
                     LANIVIGYRYDRTPVSVGDLQVEGALALILKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSVLATTTALHLADYTVTEAGFGADLGAEKFLDIKTPNLPTSPDAVVIVATLRAL
                     KMNGGVAKDALTEENVEAVRAGFANLKRHVENIRKFGIPAVVAINEFVSDTEAEIAVL
                     KELCASIDVPVELASVWADGAEGGVALAETVVKTIAENPANYKRLYDNALSVQEKIEK
                     IVTEIYRGSKVNFEKKAQTQIAQIVQNGWDKLPICMAKTQYSFSDNPNALGAPENFEI
                     TIRELVPKLGAGFIVALTGDVMTMPGLPKRPAALNMDVESDGTVLGLF"
     gene            68986..70161
                     /gene="mutY"
                     /locus_tag="ACL3EZ_000532"
     CDS             68986..70161
                     /gene="mutY"
                     /locus_tag="ACL3EZ_000532"
                     /EC_number="3.2.2.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0019104 - DNA N-glycosylase activity
                     [Evidence IEA];
                     GO_process: GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HGR0392155.1"
                     /translation="MLDLKEYGIVMWPEEKVISFREKLLAWYDENKRDLPWRRSKNPY
                     HIWVSEIMLQQTRVDTVIPYYERFLDWFPTVESLATAPEESLLKAWEGLGYYSRVRNM
                     QAAAQQIMTDFGGQFPNTYEGISSLKGIGPYTAGAISSIAFNLPEPAVDGNVMRVLAR
                     LFEVNHDIGIPSNRKIFQAMMEILINPDRPGDFNQALMDLGSDIESPVNPRPEESPVK
                     DFSAAYQNGTMDRYPIKSPKKKPVPIYLKALVVKNSQGQFLLEKNESEKLLAGFWHFP
                     FIEVDNFSQEEQFDLFHQVAEESVNFGPSPEESFQQDYDLDVDWLDVCFDTVQHVFSH
                     RKWHVQIVAGQVSDFHDFSDREVRWLSPEEFKNYPLAKPQQKIWQAYAQANLDSSQD"
     gene            70217..70921
                     /gene="yycF"
                     /locus_tag="ACL3EZ_000533"
     CDS             70217..70921
                     /gene="yycF"
                     /locus_tag="ACL3EZ_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000722069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator YycF"
                     /protein_id="HGR0392156.1"
                     /translation="MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFEAE
                     QPDIIILDLMLPEIDGLEVAKTIRKTSSVPILMLSAKDSEFDKVIGLELGADDYVTKP
                     FSNRELQARVKALLRRSQPMPVDGQEADSKPQPIQIGDLEIVPDAYVAKKYGEELDLT
                     HREFELLYHLASHTGQVITREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPE
                     YILTRRGVGYYMRNNA"
     gene            70914..72263
                     /gene="vicK"
                     /locus_tag="ACL3EZ_000534"
     CDS             70914..72263
                     /gene="vicK"
                     /locus_tag="ACL3EZ_000534"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     VicK"
                     /protein_id="HGR0392157.1"
                     /translation="MLDLLKQTIFTRDFIFILILLGFILVVTLLLLENRRDNIQLKQI
                     NQKVKDLIAGDYSKVLDMQGGSEITNITNNLNDLSEVIRLTQENLEQESKRLNSILFY
                     MTDGVLATNRRGQIIMINDTAKKQLGLVKEDVLNRSILELLKIEENYELRDLITQSPE
                     LLLDSQDINGEYLNLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSH
                     ELRTPLTSVKSYLEALDEGALCETVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATS
                     HLDVELINFTAFITFILNRFDKMKGQEKEKKYELVRDYPINSIWMEIDTDKMTQVVDN
                     ILNNAIKYSPDGGKITVRMKTTEDQMILSISDHGLGIPKQDLPRIFDRFYRVDRARSR
                     AQGGTGLGLSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAVKEEVWEDEVED"
     gene            72265..73074
                     /locus_tag="ACL3EZ_000535"
     CDS             72265..73074
                     /locus_tag="ACL3EZ_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HGR0392158.1"
                     /translation="MSEIGFKYSILASGSSGNSFYLETSKKKLLVDAGLSGKKITSLL
                     AEINRKPEDLDAILITHEHSDHIHGVGVLARKYGMDLYANEKTWQAMENSKYLGKVDS
                     SQKHIFEMGKTKTFGDIDIESFGVSHDAVAPQFYRFMKDDKSFVLLTDTGYVSDRMAG
                     IVENADGYLIEANHDVEILRSGSYAWRLKQRILSDLGHLSNEDGAEAMIRTLGNRTKK
                     IYLGHLSKENNIKELAHMTMVNQLAQADLGVGVDFKVYDTSPDTATPLTEI"
     gene            73165..73407
                     /gene="relB"
                     /locus_tag="ACL3EZ_000536"
     CDS             73165..73407
                     /gene="relB"
                     /locus_tag="ACL3EZ_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB family
                     antitoxin"
                     /protein_id="HGR0392159.1"
                     /translation="MTTITLKVSEADKTFMKAMAKFEGVSLSELIRTKTLEALEDEYD
                     ARVADLAYQEYLEDLEKGVEPITWEEMMHDLGLKDE"
     gene            73409..73663
                     /locus_tag="ACL3EZ_000537"
     CDS             73409..73663
                     /locus_tag="ACL3EZ_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA];
                     GO_function: GO:0042803 - protein homodimerization
                     activity [Evidence IEA];
                     GO_process: GO:0030541 - plasmid partitioning [Evidence
                     IEA];
                     GO_process: GO:0051290 - protein heterotetramerization
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HGR0392160.1"
                     /translation="MYKLVPTRRFIKQLKKLDRYTQKLITNYLQTNVLEDPRRHGKAL
                     VGNRVGQWRYRIGNYRVIVQIVDDELVVATLEVGHRRDIY"
     gene            73738..75609
                     /locus_tag="ACL3EZ_000538"
     CDS             73738..75609
                     /locus_tag="ACL3EZ_000538"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000150981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Eco57I restriction-modification methylase
                     domain-containing protein"
                     /protein_id="HGR0392161.1"
                     /translation="MTIDISEESLAKESADLLKILLKDRTTKKSIVWATHSYELLGKG
                     FAPSDRINPSKVTGNFANLIQPRSEKSKYEQKDRTKIRAEVFTPTWLVAKQNGYVESK
                     LGSLSLEEYVDLRWLEVTCGEAPYMVTRYDTVTGEEIPLSERVGFVDRKLQRISREVS
                     DEVTFYKLVKDAYHASYGYEYQGDSLLLARENLLATFEDYYLAKTGNQPTLEQKKEIA
                     TIISYNVFQMDGLKKSSPYSAKQKQSQQLSLFADELEVQEVEESKTHIKDWKKNRMIG
                     FERLSSEESEMKFDVVIGNPPYQETGEARDEPIYHYFIDEAYKIADKSILITPARFLF
                     KAGQTPKNWMEKMLEDKHLKVQFYELKSGKVFTGTDIKGGVAITYRDVDKDLGPIGVF
                     TIFETLNGIVKKIEKHPEFETFSDLVYPQGIYRFSNKLFSDYPNAEKLQGKGTKNKIV
                     SKSLTQLDFVFKNNEEKDHVALLGRIGSERVYRYINKKYLDLPETFENYNVFVPEANG
                     SGALGEVLSTPLIGEPLIGHTDTFLSIGNFKTKFEADACIKFIKTKFARVLLGVLKVT
                     QHNSRKTWYYVPLQDFTVNSDIDWTQSVADIDLQLDQKYDLSPEEIAFIENHVREMD"
     gene            75774..79028
                     /locus_tag="ACL3EZ_000539"
     CDS             75774..79028
                     /locus_tag="ACL3EZ_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001143847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HGR0392162.1"
                     /translation="MPVEIKTTKEIHPKIYAYTTPTVTSNEGWIKIGYTERDVTQRIK
                     EQTHTAHIATDVLWTGDAAYTEEPDKGKTFKDHDFHHFLSFHDVERRPKTEWFYFNGT
                     PEKSKNLFDKFVQHDLSGYQPGKGQDYTLRQEQEEAVAKTLAYFQEHAGGKFLWNAKP
                     RFGKTLSTYDLARRMEAVNVLIVTNRPAIANSWYDDFETFIAGQTTYKFVSESDSLKS
                     RPILSRQEFLGILADDVRQLAFISLQDLKGSVYLGGEHDKLKWVTDLHWDLLVIDEAH
                     EGVDTFKTDQAFNKIRRNFTLHLSGTSFKALAKGDFTEEQIYNWSYADEQAAKYSWSL
                     EQEEENPYESLPQLNLFTYQMSQMIGEKLEKGAQIDGENIDYVFDLSEFFATDDKGKF
                     IHEHDVRNWLDTLSSNEKYPFSTKELRNELKHTFWLLERVASAKALKALLEEHPIYEN
                     YEIVLAAGDGRMSEEDDKVKLKSLDLVRKAIAENDKTITLSVGQLTTGVTIPEWTGVL
                     MLSNLKSPALYMQAAFRAQNPYSWSDNKGNHFRKERAYVFDFAPERTLILFDEFANNL
                     SLVTAAGRGTSATREENIRELLNFFPIIAEDRAGKMVEIDAKAVLTTPRQIKAREVLK
                     RGFMSNLLFDNISGIFQASQTVLDILNELPVEKEGKVQDSSDLLDFSDVTVDDEGNAV
                     VDHEIVVNQQMRLFGEKVYGLGESVAELVTKDEERTQKQLVNDLSKTVSSVIVEELKA
                     DYSLKTRETEQIKKQITATLENEIRKNDIERKISEAHIKQELQQQLKEANDKAQKDKI
                     QEDLEKRLEENKLIHKEKLEQTLKKEVEKMPEKFIEQVEIKRVEQLKQSAQDEIRDHL
                     RGFARTIPSFIMAYGDQTLTLDNFDAFVPEHVFYEVTGITIDQFRYLRDGGQDFAGHL
                     FDKATFDEAIQEFLRKKKELADYFKDQKEDIFDYIPPQKTNQIFTPKRVVKRMVDDLE
                     KENPGIFDDPSKTFIDLYMKSGLYIAELVKRLYNSNGLKEAFPNPEERLKHILEKQVY
                     GFAPSEIIYNISTNFIFGNLSKDISRKNFVLADTIPAAKEGSIQKLVDSYFENN"
     gene            complement(79414..80400)
                     /locus_tag="ACL3EZ_000540"
     CDS             complement(79414..80400)
                     /locus_tag="ACL3EZ_000540"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019768616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004459 - L-lactate dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HGR0392163.1"
                     /translation="MTSTKQHKKVILVGDGAVGSSYAFALVNQGIAQELGIIEIPQLH
                     EKAVGDALDLSHALAFTSPKKIYAAQYSDCADADLVVITAGAPQKPGETRLDLVGKNL
                     AINKSIVTQVVESGFKGIFLVAANPVDVLTYSTWKFSGFPKERVIGSGTSLDSARFRQ
                     ALAEKLDVDARSVHAYIMGEHGDSEFAVWSHANIAGVNLEEFLKDTQNVQEAELIELF
                     EGVRDAAYTIINKKGATYYGIAVALARITKAILDDENAVLPLSVFQEGQYGVENVFIG
                     QPAVVGAHGIVRPVNIPLNDAETQKMQASAKELQAIIDEAWKNPEFQEASKN"
     gene            80594..83062
                     /gene="gyrA"
                     /locus_tag="ACL3EZ_000541"
     CDS             80594..83062
                     /gene="gyrA"
                     /locus_tag="ACL3EZ_000541"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001152996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006259 - DNA metabolic process [Evidence
                     IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HGR0392164.1"
                     /translation="MQDKNLVNVNLTKEMKASFIDYAMSVIVARALPDVRDGLKPVHR
                     RILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRYMLVD
                     GHGNFGSMDGDSAAAQRYTEARMSKIALEMLRDINKNTVDFVDNYDANEREPLVLPAR
                     FPNLLVNGATGIAVGMATNIPPHNLGETIDAVKLVMDNPEVTTKDLMEVLPGPDFPTG
                     ALVMGKSGIHKAYETGKGSIVLRSRTEIETTKTGRERIVVTEFPYMVNKTKVHEHIVR
                     LVQEKRIEGITAVRDESNREGVRFVIEVKRDASANVILNNLFKMTQMQTNFGFNMLAI
                     QNGIPKILSLRQILDAYIEHQKEVVVRRTRFDKEKAEARAHILEGLLIALDHIDEVIR
                     IIRASETDAEAQAELMSKFKLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIAD
                     LADILAKPERVSQIIKDELDEVKRKFSDKRRTELMVGQILSLEDEDLIEESDVLITLS
                     NRGYIKRLDQDEFTAQKRGGRGVQGTGVKDDDFVRELVSTSTHDHLLFFTNKGRVYRL
                     KGYEIPEYGRTAKGLPVVNLLKLDEDESIQTVINVESDRSDDAYLFFTTRHGIVKRTS
                     VKEFANIRQNGLKALNLKDEDELINVLLTEGDMDIIIGTKFGYAVRFNQSAVRGMSRI
                     ATGVKGVNLREGDTVVGASLITDQDEVLIITEKGYGKRTVATEYPTKGRGGKGMQTAK
                     ITEKNGLLAGLMTVQGDEDLMIITDTGVMIRTNLANISQTGRATMGVKVMRLDQDAQI
                     VTFTTVAGAEKEEVGTENETEGEA"
     gene            83062..83805
                     /gene="srtA"
                     /locus_tag="ACL3EZ_000542"
     CDS             83062..83805
                     /gene="srtA"
                     /locus_tag="ACL3EZ_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase SrtA"
                     /protein_id="HGR0392165.1"
                     /translation="MSQKNNKKKNKRKNLLTNILAGFLILLSLALIFNTQIRNIFIVW
                     NTNKYQVSQVSKEKLEENQDTEGNFDFDSVKAISSEAVLTSQWDAQKLPVIGGIAIPE
                     LEMNLPIFKGLDNVNLFYGAGTMKREQVMGEGNYSLASHHIFGVDNANKMLFSPLDNA
                     KNGMKIYLTDKNKVYTYEIREVKRVTPDRVDEVDDRDGVNEITLVTCEDLAATERIIV
                     KGDLKETKDYSQTSDEILTAFNQPYKQFY"
BASE COUNT        25672 a        15009 c        18429 g        24752 t
ORIGIN      
        1 gcagacgctc aaaccattgt cgcgtctaaa aataaaatct caattcaaga agacaagaaa
       61 gcgctttaaa accagtagac cttttcataa ggttcgcttg atgtaccaaa tagtacgccc
      121 atgcaaaaga atatctattt tgttgtcttg gacctgcata cgacggatag agataaaatt
      181 atccagctat tcaaggattg gacggattat agtgccaagt tggtcgaggg ggaattggtt
      241 aaaaaagatg gacagaatgc tctctttcct ccgagcgata ctggtgagac agttgggctc
      301 aatcctcatc gtttgacgct gacttttggt gtatctgcaa gtttcttgaa aaggatgaac
      361 ttggaaaaca agcgccctcg actgttcagg gatttacctc tatttcctaa ggagcaatta
      421 cgtgaaaaat atactggtgg agatattgtg attcatgctt gtgcagatga tgagcaaatt
      481 gcctttcacg ctattcgcaa tctcatccgt aaggggagaa atgcggtgcc ccttcgttgg
      541 agtcagtctg gatttgcagc tatcggggat cgaatggaga ctccgtggaa cctctttggt
      601 tttaaggatg gaacagcaaa tccaaccaag gagcaagact ttgaccgcgt tatctgggct
      661 gatagtaagg actggatgga aaatggttct tatatggcag ttcgtcggat tcagatgttt
      721 ttagagacct gggaccgcac tagtctcgaa gaacaagaaa atacctttgc tcgttacaag
      781 gaaagcggtg ccccctttgg taagaaaaat gagtttgatg aagtggattt gagtctctta
      841 cctgatgatt cgcatgtttg tttggccaaa gaagtggata agccactttt acgtcgttct
      901 tattcttact cagatggcat tgatgaaaag actggtcagt ttgatacggg attgctcttc
      961 atttctttcc agaaggatcc tgataacttt gttaaggttc aaactaacct aggtgctact
     1021 gataagatga atgaatacat cactcacata ggtagtggac tttttacttg ctttggtggt
     1081 gtggagaaag gaggctacat tggtcagaaa ttattggaag gctaaaagct ggttactagt
     1141 tttagctttg tcatttttaa ttctttcccc agcaggtgcc caagaaagct tgagtttttt
     1201 ctttgtgaaa atcacagatg catccaaaac ggttaaaaat ggtggtcaga ctgagaccca
     1261 gaaactcgtt acgaagatgg catcagactt cgaaagagta gaaaataagg attctgaggt
     1321 tggtaagatt gttaaggaaa agttagctct atctggagat attactgaag ccaaactcac
     1381 cgaaatttcc tcagctctat tagcttttga aaaagaacaa aatcctgttg acctagatgc
     1441 ggaaaaggaa aaattggtaa accgtctaag tcctcgtttt gaaaccttag aacaggccat
     1501 tgcctccaaa gatttggaaa aagtccgaga agcttttaag aaaatgaatt ccacttggac
     1561 catcaatgaa agtgtggttc gtgacaatag tacagctcat tatggacgtg ttgaaacagc
     1621 tatttccttc ctgcctagta gcatggaaac cgaacctaca gatgagtctg gaacatgaaa
     1681 acagcagttg atttcaagaa acaaaaaaga acagccgaaa ctgttctctt atcattattt
     1741 gagaccgtat tttttgttga aacgatccac gcgtccatct gcttgagtga acttttgacg
     1801 tccagtgtag aatgggtgtg agtctgatga aatttccaca cggatcaatg ggtaagtttc
     1861 gccttcgaac tcaactgttt cgttagagcg ttttgttgaa ccactaagga attggtaacc
     1921 agtagttgtg tccatgaaga caactgggcg atattctgga tggatatctt ttttcatttt
     1981 gcaatatttc ctttctgcca tggtctcttt gcgagccata gattgttacc atactagtct
     2041 atcagattct gaaaagtttg gcaagtattt tatcagtttt taagcaagtt ttttaacttt
     2101 tggtagatga tttcgttttc ctctaggcta taggaattag caccacttgc tagagggtgg
     2161 cctccaccat catgtttctt ggcaatttca ttgataggat ggattttact gcgtaagcga
     2221 actcggtagt ggccatcagc ctgttcgaca aaaattcccc agagactcac tctgtcaatg
     2281 cgtccaggtg caccgacaat ggctgcagtt tcagcatcgg ttacattgta ttgtttcaag
     2341 acttcttgac tcaggataac gcgagcagca ccattttcat ccacttccag atggtcgtag
     2401 atgtagcctt gcagtttagc aattttgtag ctcatagtgt ccattttgcg agtgagagcc
     2461 gcaaagtcaa agttatgttc tctcaaataa gcagccaggc gaagagtccg tgcagtggta
     2521 gaagggtaga ggaagcgacc tgtatcaccg acaattcctg caaagagcaa ctcagcatcg
     2581 cgatctgcca aggctagttg ggttgtttgg gcaaataggg taatcatctc gctagcgcta
     2641 cttgaactag tatcgaccca agacaggtca ccgtatacat catcatttgg atggtggtca
     2701 atcttaatga gaaaatcacc ttgactatag cgcttatcat cgatacgagc agtattagct
     2761 gtatcacaga cgatgacaag tgcgccttgg taggctctat cttcaacaag atccatctca
     2821 gccatccaag taagagttgg ttcatcaaaa ccgacggctt tgatggtttt ttctgggaaa
     2881 tgatgttcca gcaaggcttt caatcccacc tgacttccca aggcatcagg gtctggtttc
     2941 atatgacgat gaatgataat ggtgtcgtat tctttaattt tttctaaaat ttgttggcaa
     3001 atctccataa ataacctcaa ttctttctca tttcattgta gcacaagaat ttttattttt
     3061 aaaatgaaaa agatgtgata taatggagaa agataaattg aggaggacga tatggcatta
     3121 gcaaaaattg tatttgccag tatgaccggt aataccgaag aaattgcaga tattgtagca
     3181 gacaaattac gtgacttggg cttggatgtt gatgttgatg aatgtacaac tgttgacgct
     3241 tcagacttct tggaagcaga catcgctatc gttgcgacct atacttatgg tgatggtgaa
     3301 ttgccagatg agatgatgga cttctacgaa gatctagcag atctcaactt gaatggcaaa
     3361 atctacggag tggtcggctc aggagatacc ttctacgatg aattctgtaa ggctgttgat
     3421 gactttgacc gtgtctttgt ttcaacagga gcagaaaaag gttctgagtg tgtcaaagtt
     3481 gatctttctg ccgaggaaga agatattgaa cgcttggaac aattcgcaga agaattggtt
     3541 gctaaagtag gataagcata aaagtgcgct gatgtaatca atcagtgcat ttttcttatc
     3601 gagagttggg attttactag cctaattgat ggctttttga tacaataatt caaataaagg
     3661 aggagactgt atggatttag atattattcg tcaagaaatc gatcaaatcg acgaccaaat
     3721 tgtcaaactg ttagaagaac gaatgcattt agttgagggg gtggttgctt ataagaaagc
     3781 ttcaggtaaa ccgattttag atactaagag agaagaagtt atttttgaaa aggttgggag
     3841 tcgtgtagag gacaagcgct atcaggagac tattgtagcg actttttcgg acatactcaa
     3901 acgttcgcgt gattatcagg atcaaaatat caaatgaaaa aagaacaatt ttatccgcta
     3961 ggaatttttc tagctgctat gttgggcgga cttgtccgat atctagtttc cacctggtta
     4021 ccagccagtc cagactttcc ttggggcact ctctttgtca actatctggg aattttctgc
     4081 ttgatttttc ttgtcaaggg ctatctggtc tataagggga ctagtaaggg cttgatttta
     4141 gcactgggga cgggtttttg cggaggttta acaacttttt ccagcctaat gcttgatact
     4201 gtgaagctgc ttgatacagg gcgttatttt agtttagtcc tgtatttgct tttgagcatc
     4261 ggtggaggcc tactcttagc ttattttcta gggaggaaga aatggtaatc gtctatcttg
     4321 caattgcttg tggtttcgga gctttagtgc gctatttatt ttctcgctat aatcaagctt
     4381 ctaaattgcc actcggaacg ctcatagcta atcttttagg ttgtttttta attggagtat
     4441 tttacaatca tgtagagtct aaggaagtat atgctattct agcaacagga ttttgtggcg
     4501 gtttaacaac tttttcgacc ttgaatgacg aacttcaaag actgctaagt gataagaagg
     4561 tcttttattc ttacctgact ttgacttaca taggtggttt ggttgcgatt tttttaggaa
     4621 ttttgctata aatttcttta ctttttttta gaaatttggt aaactgtatc ttgtgtgtaa
     4681 tggacgcaca aaaatacagt ttatccgctg aggaagattc ctcaagattg acaaagatag
     4741 gagaataaaa tgaatccatt aatccaaagc ttgactgaag gtcaacttcg tacagatatc
     4801 ccatcattcc gtcctggtga cactgttcgt gtacacgcga aagttgtcga aggtaaccgt
     4861 gaacgtatcc agatttttga aggtgttgtt atcgcacgta aaggtgctgg aatctcagaa
     4921 aactacacag ttcgtaaaat ctctaacggt gtaggtgttg agcgtatctt cccaatccac
     4981 actccacgtg ttgaaaaaat cgaagttgtt cgttacggta aagtacgtcg tgcgaaattg
     5041 tactacttgc gtgctcttca aggtaaagca gctcgtatca aagaaatccg tcgttaattc
     5101 gactaaaaaa ctctgctttt cagcagagtt tttatctagc tcccttagtt caatggatat
     5161 aacaactccc tcctaaggag tagttgcagg ttcgattcct gcagggggca gtaattagac
     5221 atcaaaaacc gctcagctga gcggttttag tctattcttt ccttttacag tacccatgtt
     5281 cggatggcgt gggcaacgcc ggattcgtca tttgttttag tgatgtattt ggcgattttt
     5341 ttgatttctg gatttccatt ttccatgaca acggggtttc caacgacttc cagcatggca
     5401 cggtcatttt cttcgtcacc gattgccatg gtttcatctt tggtcaatcc gagtttttca
     5461 gccaagtgag taatggctga acccttgtct acattctttg taaggagttc gaggtagaaa
     5521 ggagcagatt tgttgatgga gtagcgctcg taaaattctg ctggaatttt ttcaatcgca
     5581 gcatcgagaa tttctggttc atcgataaac atacatttaa caatttcttt gccagccatt
     5641 tcttcagggg tacggtagaa gataggcatg ctgacgaggg ttgattcgtg tacagtgtat
     5701 gttccgatat tgcgatttgc agtatagata ccgtccttgg taatggcatg catgtggaca
     5761 ccgagcttgc gactgaggaa ttccatatcc agataatcct cataggtcaa ggattcgctg
     5821 ataatctcat ggccagtagc agtttcttgg acaagggcac cattgaaggt caccacatag
     5881 tcaccttggt ctctcaactg caagtcgtcc agaagtttgg caacacctgc gatggggcgg
     5941 ccagttgcaa tcacgacttt gacaccagct tctttggcat cttggatggc agaaaagact
     6001 tcaggagtaa tctccttttg actgttgact agggttccgt caatatcgac agcgattagt
     6061 ttaatactca taaaattcct cttctagttt ttatttgggg taaaatgatc gttctcaatc
     6121 aagtgtaaaa attgctgggt aatgcttgca aagatgctgt tttggtccaa catttctttt
     6181 ggaaaataaa agcgattatc tccgtggcga ctgccagcaa gggattggac gataggagac
     6241 aggctagaga gttcggccag ttctccattt ttttgtaaaa tctcaatctg tgtccgtgga
     6301 ttttgagatt cgggacgata gatatcataa gggaggtcaa agttcttatg aatggcagta
     6361 tagtagtcgg gatcaaagcc gatgtcctca accaattttc tcatgctagt aagttgatct
     6421 tggtcctctt gtgaaaaggt aatggattta aagaccttgc ggttgacaaa gcgttgagat
     6481 aaatctgcaa gaattttgtc aggactagtc atccaaagct ggaagtaggt attcatcacg
     6541 ccatcatcca gagccagata gtcagtcaag gtcacatttt tttcgaagaa aggcaggaga
     6601 tgtggggaag ttcgtgcaaa gaaattcttg tcctcagggt agagttcctt ggcgcgcttg
     6661 agaagattct gtaggagaac ttccatggcg cgtgttgctg ggtggaaata aacctgcatg
     6721 tacatctggt agcgactgag gacgtagtct tcgatggcgt gcatgccatt gcgctgaaag
     6781 gcgataccat tttcgacagg acgaatgact cggaggatgc gagtcaggtc aaattcccca
     6841 taggatgctc ctgtaaaata ggagtcgcgc aagagatagt ccatgcgatc tgcgtcaatc
     6901 tgactagaaa tgagctgcac gacctgctta ttaggatagg tatggtctat gacactggca
     6961 actttttctg gaaaatcggg cgctacttgt agcaagactt ggtgaatctc tgtctcagga
     7021 ttttgaataa tctcctgagt aatggcttca tggtctgtat caaagagatg ttcaaaagta
     7081 tgggagtagg cgccatgccc aaggtcatgt aggagagcag cggtcatggt caagagagac
     7141 tcggcaggat tccattcctc aggatatttt tcttcaaaaa tttctgtgat acgtcgtgca
     7201 atctcataga ctcctagaca gtgagagaag cgactgtgtt ctccaccgtg gaaggtataa
     7261 ctggaagttc ccagttgttt gatccggcgc aaacgctgaa attcttttgt gttaatcaag
     7321 tcatagatga tttgattatt gacatggatg tagttgtgaa ctggatcacg gaatactttt
     7381 tcgttcatat gaccattata gcaaaatcct gctctttttg gtaaaatagt aggacaagag
     7441 acaagaaaga ggacctgatg tgaagattcg gatgcgaaat acaattcagt ttgatgagca
     7501 gttggaagtg attgaccagc tttatgatgt ggaagtgcat gaaaaaggag attatagcta
     7561 cctgcttttc tataatgagg aaaaggaaaa agtagtgatt aaatttcatg gtcaagaact
     7621 tgtgatgagc cgattttcta atcccaagac cattatgcgc tttctaaagg atagcgatag
     7681 tttagcctat attcctacac ctatgggcat gcaggagttt atcatccaaa cgagccatta
     7741 tcaagttgat aggcaaaaga ttgaactaga ttatcaacta caaaatcaag agggacatcc
     7801 ctttgccagc tatcaattgg aaattacttg gggctaggct catgtctttt tcaaatttag
     7861 ctatctatct tcttggatcg gcttcctagt gtggtagatt aggctaattt ttggtataat
     7921 aaaagttatg gaaatcgaaa aaaccaatcg tatgaatgcg ctctttgaat tttatgcggc
     7981 gcttttgaca gataagcaaa tgaattatat cgagctctac tacgctgatg attacagcct
     8041 tgctgaaatt gccgaggagt tcggtgtcag tcgtcaggct gtctatgaca atatcaagcg
     8101 aacagaaaag attctggaag attatgagat gaaattgcac atgtactcgg actatattgt
     8161 ccgcagtcag atttttgatc agattttgga gcgctatccc aaggatgact ttctgcagga
     8221 gcagatagaa attttaacaa gcattgataa tagagaataa gaggaagaaa aatggcattt
     8281 gaaagtttaa cagaacgttt gcagaacgtc tttaaaaatc tacgtaaaaa aggaaaaatc
     8341 tctgaatctg atgtccaaga ggcaaccaaa gaaattcgct tggccttgct cgaggccgac
     8401 gttgccttgc ctgttgtaaa ggactttatc aagaaagttc gtgagcgtgc agtcgggcat
     8461 gaggtcattg atacacttaa tcctgcgcaa cagattatta aaatcgttga tgaggaactg
     8521 acagccgttt taggttctga tacggcagaa attatcaagt cacctaagat tccaaccatc
     8581 atcatgatgg ttggtttaca aggggctggt aaaacaacct ttgctggtaa attggccaac
     8641 aaactcaaga aagaagaaaa tgctcgtcct ttgatgattg cggcggatat ttatcgtcca
     8701 gctgccattg accagcttaa gaccttggga caacagattg atgtgcctgt ctttgcactt
     8761 ggaacagaag taccagctgt tgagattgta cgtcaaggtt tggagcaagc ccaaactaat
     8821 cataacgact atgtcttgat tgatactgcg ggtcgtttgc agattgatga gctcctcatg
     8881 aatgagcttc gtgatgtgaa agcattggct caaccaaatg aaatcttgct tgtcgttgat
     8941 gctatgattg gtcaggaagc agccaatgtt gcgcgtgagt ttaatgctca gttggaagtg
     9001 actggggtca tccttaccaa gattgatggc gatactcgtg gtggtgctgc tctgtctgtt
     9061 cgtcacatta ctggaaaacc aatcaagttc actggtacag gtgaaaagat tacggacatt
     9121 gaaaccttcc acccagaccg catgtctagc cgtatccttg gtatggggga tatgctcact
     9181 ttgattgaga aagcttctca ggaatacgat gaacaaaaag cccttgaaat ggctgagaag
     9241 atgcgcgaaa acacctttga ttttaatgat ttcatcgatc aattagatca ggtgcaaaat
     9301 atggggccga tggaagactt gctcaagatg attccaggta tggccaacaa tccagccctt
     9361 caaaacatga aggtggatga acgccagatt gctcgtaaac gtgcgattgt gtcttcgatg
     9421 acacctgaag aacgtgaaaa cccagatttg ttaaatccaa gccgtcgccg tcgtattgct
     9481 gctggttctg gaaatacatt cgtcgaagtc aataaattca tcaaggactt taaccaggct
     9541 aaacagctca tgcagggtgt tatgtctggg gatatgaata aaatgatgaa gcaaatgggg
     9601 attaatccaa ataaccttcc taaaaatatg ccaaatatgg gaggaatgga tatgtctgcc
     9661 cttgaaggaa tgatgggaca aggcggtatg cctgacttat cagctctcgg aggagcagga
     9721 atgccagata tgagccagat gtttggtggc ggtttgaaag gtaaaattgg tgaatttgcc
     9781 atgaaacagt ccatgaaacg tatggctaac aaaatgaaga aagcgaagaa gaaacgcaag
     9841 taagacaaga gattgatgca aatctcattt gatgagaaaa taaagtaaaa atttctatga
     9901 taaaacgtac agtatcaagg ttttagaata tctgatatta tacgtttttt gattttaata
     9961 attttgttaa gacactttta ttatggtata cgaaaaatcc actcagctgt ctgagtggat
    10021 taggtgtatt tagactctta gtctttattt tcgtatggca agatcaagtt caagatgatt
    10081 cctgtcatgg ctgaaagggc agtacctgaa agtgtaactg gaccaagttt aaggatagct
    10141 cctccaagtc caagaaccaa catagcactt gcgatgatga ggtttcgcat ttgagcgaaa
    10201 tcaacacgtt ctttaatcaa gactttcaaa ccattgctgg cgataacccc atagagaagg
    10261 attgacatac caccaagtac agcgtttgga atagttgaaa tcaaggcagt gaatttacca
    10321 aggaagctga gggcaatcgc gatgaaggca gcgttacgga taactgagac agaagcgata
    10381 cgagtcatac cgataacccc tgtattttct ccgtaagttg tattggctgg tccaccaagg
    10441 aaggcagaaa cagaagttgc gataccgtca ccaagaagag tacggtgaag acctggttct
    10501 tttaagaatt gacgaccaca gatttgaccc aaaacagtat ggtctccgat atgttcagaa
    10561 attgttacga tagcgattgg caagatagcg atggcttctg gaccaaagta aagattgtac
    10621 tctttaaagg caccacctgt gctaaatggc aagtagaaac caggaatttc gaaccagttg
    10681 gctttaagaa ctggtataaa gtcaaccaag ccaagagtta gtgcgaaaag gtaaccaccg
    10741 ataatggcaa agaggaatgg aatgattcgt aggaagcctt ttccttttgt attgataaag
    10801 gcagcaatta ggaaagtaac aacggctacc agagcatttt tccaatttcc gtctgctaca
    10861 agacctgcat tggtaacagc tgaacctgca agtccaagac cgataacgat gatcatagga
    10921 ccgataatga ttggtggcaa gagtttatca atccattttg ttcctacaaa tcggatgctg
    10981 gtagcaacaa ggacatagac caaaccagtc aagataaccc ctgtttgggc agcagataca
    11041 tcacccccca tttctttcat agccagtgac atagctgtga taaaggcaaa tgaagaacct
    11101 agataaactg gaactttaaa accagtagca atcatgtaga tgagtgttcc aacacctgaa
    11161 gcaaaaaggg caacagatac aggcattccc aaaatcaatg gtaccaagat ggtcgcacca
    11221 aacatggcga aaacgtgttg gaagctaagg agaattcctt ttccagccga aggacgttgg
    11281 tcaacgtcta ataacaaatc aacagttgat tcttgtttca tataaacctc acttttgggc
    11341 atcagaaaag agcccattat tttacagcaa taggccctca gagtaagact tctctaaaat
    11401 ctagacttta aagagtttca aatatttttg cgtcttcgtc acctcacggg atgacattaa
    11461 aaacctttgc ttaggatagt atagcagaaa aaaatgattt tgtaaatcat tttttcccga
    11521 gcctagaaat aaaagagcga ggctgatttt gtaaatcatt ttttcccgag cctagaaata
    11581 aaagagcgag gttgattttg taaatatttt tttacttaaa aatttaaagc gggcgtttat
    11641 ttggcatacc agccttacgt ggatatttat ttggtgtttc ttttttcttt tctaccactg
    11701 tgatgtaacg cggatctcta tttggtaggg cgtagctgag attgtcttcg accttactaa
    11761 aaaggagatt gagggcattc ttagcttcta acaactcctc aggcgcattg ctggccttga
    11821 gtgccaatag ttttccacca accttaaggt agggaatagt caattcagat aggacctgca
    11881 tacgggcaac cgcacgagct gttacaaaat catattgagc acggaagttc ttgtcttggg
    11941 caaaatcttc ggcacgtccg tggtagaaat gaactccgtt caaatccagt tcttgagcca
    12001 agagttgtag gaagttgatg cgcttattga gtgaatcaat aatggtcaca tctaactccg
    12061 gatagagaat tttcattggt agactaggaa atcctgcccc agccccgata tcaagaagtt
    12121 tgatagtttc attgggaatc aaaccttgaa gaatgggtgc aatcgaatcg taaaaatgtt
    12181 tgagataaac ttcttccttg tccgtaatcg ccgtcaaatt aatcttctca ttccactcga
    12241 ccaagagctc aaaataacgt tcaaattgtt ctttttgctg gtccgaaagt ggaagattct
    12301 gctcggcaag caagttgtaa aatgtttctg gtttcatagt tatttccttc tttagtatca
    12361 tcttatttta ccacaatcat taaaaatttg atatactggt actaatctaa aagtagaaag
    12421 gacttatatc atgacttgga ttattcttgg agttatcgct cttattgtta tttttgtgat
    12481 tgttagctat aacggtttgg ttaagaatcg tatgcaaacc aaggaggctt ggagtcagat
    12541 tgatgttcag ttgaaacgtc gaaatgacct cttgccaaac ttgattgaga ctgtaaaagg
    12601 ttatgccaaa tatgaaggtt ctacccttga aaaggtggca gaactacgta accaagtggc
    12661 ggcagcgact tcaccagcag aagctatgaa agccagtgat gccctcactc gtcaagtttc
    12721 aggtattttt gcagttgcag aaagctatcc agatttgaaa gctagtgcta actttgttaa
    12781 attgcaagag gagttgacaa acacagaaaa taaaatttct tactctcgtc aactctataa
    12841 cagtgttgtc agcaactaca atgtaaaatt agaaactttc ccgagcaata ttatcgctgg
    12901 aatgtttgga tttaaagcgg cagatttcct tcaaacacct gaagaggaaa agtcggttcc
    12961 taaagttgat tttagcggtt taggtgacta agatgttgtt tgatcaaatt gcaagcaata
    13021 aacgaaaaac ctggattttg ttgctggtat ttttcctact cttagctctt gttggttatg
    13081 cggttggtta tctctttata agatctggac ttggtggttt ggttatcgca ctgattatcg
    13141 gctttatcta cgctttgtct atgatttttc aatcgacaga gattgtcatg tccatgaatg
    13201 gagcgcgtga ggtggatgag caaacggcac cagacctcta ccatgtagtg gaagatatgg
    13261 ctctggtcgc tcagattcct atgccccgtg ttttcatcat tgatgatcca gccttaaatg
    13321 cctttgcgac aggttctaat cctcaaaatg cggctgttgc tgcgacttca ggtctactag
    13381 ctatcatgaa tcgtgaagaa ctagaagctg ttatgggaca tgaagtcagt catattcgta
    13441 attatgatat ccgtatttcg actattgcag ttgcccttgc tagtgctatc accatgcttt
    13501 ctagtatggc aggtcgtatg atgtggtggg gtggagcagg tcgcagacga agtgatgatg
    13561 accgagatgg aaatggtctt gaaatcatta tgctagtggt ttccctacta gctattgtac
    13621 tggcacctct cgctgcaacc ttggttcagc tcgctatttc tcgtcagagg gaatttctgg
    13681 cagatgcatc tagtgtcgag ctgactcgca atccccaggg aatgattaat gccctagata
    13741 agttggacaa tagcaaacct atgagtcgcc acgtcgatga tgctagcagt gccctttata
    13801 tcaatgatcc caagaaaggt ggggggttcc aaaaactctt ttatacccac ccacctatct
    13861 cagaacggat tgaacgttta aaacatatgt aaaatgaagg ctggaaaaaa gtctttaaaa
    13921 tctgaaaaac gcataatatc aggtgtgaaa acttgatatt atgcgtttta ctatgggaag
    13981 atttacttct ttttctccta aaattgtgtt tttgccccac ctatctgcta tgttgcaaat
    14041 ttataaatct tctaaattaa ctagcttcaa accgtgttct gtcatgcgat agatgatcga
    14101 gcagacttct tttaagaaac gacggtcatg cgaaacagtg atgagaccgc caggataagt
    14161 ggcaaagagt tttctgattt ggggttgaga agtgggagaa aagtttcgtg tgggttcatc
    14221 cagcaggaga aagtttggtt tgcgcaggac taaatccaaa agcaggagtt ttccctgttg
    14281 tccgccagat aaggagcgaa tttgatgctg catttctgga taactgaaat tgagactagc
    14341 taggtgagat tggattttct gtagttcctc tttttcccca gttttactga gataggctat
    14401 tggggataaa tccaattgca gttttttgtg gtaatcttgt ggcataaaac caagtgaaat
    14461 ctctctttta tcattcagaa gtctctgtaa cttggctaac agagttgatt tcccaacacc
    14521 atttggcccg ataataccga ttttttcttg gccacggaca gttagttgta gtttttgaac
    14581 caaaactcgg tcgtcaatgg acaaattttc tttttccagt tggactaaga ctttagaagc
    14641 tggtaatggt tggatgtctg aaaagaaaag ttggatttgt tcctcttcaa gtggtttttg
    14701 agtcatggac tgagctgcct tttcgtagcg tttttcttgt gagaggacag ttttcatctt
    14761 tttagccaat aggcgaccgg cagtactatc tttggtagct cgaagcgcag tttctacatt
    14821 ttgcttaact ctccgatgtt tttccatggt tttatcgtag gctctttggt tgttagcagc
    14881 ttgctgactt tgtttggcaa aattagcctt tctctgctca ctatagctat catagtctaa
    14941 atgctctact agcgtttccg cttctttacg gtgtttgacc agtcgcaagt gaacaatagt
    15001 gtctgccgtt tcagaaagaa agtcttcatc atgggaaatg aaaataacgg tttgcctggt
    15061 cttttgaatc tggcctttta gccaatcaac tgtctcaagg tctaggtcat ttgaaggttc
    15121 atctaaaaat agaatctcaa agggtttggc taactcatgg ataagctgaa ttttcaaagc
    15181 ttctccccct gatagattgc caatctcttg gtcacttgcg aaacgattgc tatcaaaatg
    15241 caattcctcc gccaaacgat agaggatact gtagtctaaa tcaatagaat ctaaaaagaa
    15301 gtagtcgtgt aaagttttct ttttcagctc ctcgggaagt ttttgaggaa tgtaggccag
    15361 tgactgatag tcagattgga tgtctccctt gatagtgaaa tcagacaaat cttcccccat
    15421 taaagtttta agtaaggttg atttaccatt tccttcttcg ccaataatag ctaccttttc
    15481 cccgtcttgt atggtcatgc ttaggtcaga gacaaggtct cgtaaatctt tgttttgtgt
    15541 gatggtcagg tgattgattt ttatcatact attgcccttt ctagaatgtc gatagtgcat
    15601 aacaaaaagc tctactttac ctagtagagc ccaaagtcta tgtcaaaaaa actctattaa
    15661 catgccagaa aaagagcata aaagagcaca caaaaagaga caaaaacaag atctactaaa
    15721 taaaggttct ttatttgata gacttagttg ttcatgtctc ccttacctcc gagtattagt
    15781 atctttatat tataccttta aggaaatttt gtcaacagaa aactggaaat tctatgctct
    15841 aaaatccaaa aacaggtcca tagagactta gtacgtgttt gacatactcg taatggattt
    15901 tatcatagtt tcgccaagca gtgcgtgctt gattgtttag ttttaggcta cccagtccaa
    15961 tcagaggact ggtgggttgg taaaatttct caagattaat taagatactg ttgttcaact
    16021 tttctgtttt ttgagctctt gcatagtagt gtttagcagc tcttgtagtc gaatatcatc
    16081 tgccgtaacc tgtttacagt tttggtagct tttatttaac ttggatagga gttgaatgag
    16141 tttcttgtct tccatgtgag catcctcctt gatctgatgt actctttccc tatagtatag
    16201 cactaaaaaa taaaactatc atagtaaata tgttaaaatt tgaattttaa ttacaaagtt
    16261 tggtgtgctg atttgtagcc ttttcatggt ataatcaaga gagtaaatct ttatggagga
    16321 agtatgaaat taaatattca agaaattcgt aagcagtctg aaggtttgaa ctttgaacaa
    16381 acgttagatt tagttgatga cctgcgtgca cgtaatcaag aaattttaga tgtaaaagat
    16441 atccttgcag ttgggaaagt acaatatgaa gaccgtatgt atttcttaga ttatcaacta
    16501 tcttatacca ttgttcttgc ttcgagtcgc agtatggagc cagttgagtt agttgaatct
    16561 tatccagtca cggaagtttt catggaaggc gcaactaacc agctagatca agaagtttta
    16621 gatgatgact tggtcttgcc catcgaaaat ggggcgcttg accttgctga gagtgtatca
    16681 gacaatatcc tgctaaacat tcctatcaag gtcttgacgg ctgaagaaga agctggtcaa
    16741 ggatttgtct caggaaatga ctggcaaatc atgacagagg aagaatacca agctcaacaa
    16801 gcagtaaaga aagaagaaaa cagtcctttt gctggcttac aaggactatt tgacggagat
    16861 gaataatggt cttgtcaaaa aaacgagcac gaaaggtgct agaagaaatc attgccctct
    16921 tcccagatgc caagcctagt cttgatttta ccaatcattt tgaactcctg gttgcggtca
    16981 tgttatcagc ccagacgaca gatgcagcgg taaataaggc cacaccaggt ctctttgttg
    17041 cctttccaac accccaagct atgtctgtag cgacagagag tgagattgct tcacatattt
    17101 ctcgcttggg attgtatcgg aataaagcta aattccttaa aaaatgtgcc caacagttac
    17161 tagacgattt tgatggtcaa gtccctcaga cacgtgaaga attggagagt ttggcaggtg
    17221 ttggtcgcaa gacagccaat gttgtcatga gtgtaggatt tgggattcca gcctttgcag
    17281 tggatactca tgtggagcgt atttgcaaac accacgatat tgtcaaaaaa tcagcgacgc
    17341 cacttgaggt ggaaaagcgg gtcatggata tcttgccgcc tgagcagtgg ttagctgccc
    17401 atcaggccat gatttatttt ggaagagcca tttgccatcc aaaaaatcca gagtgtgacc
    17461 agtacccaca attatatgat tttagcaatt tgtaagatgc tacattgaaa ctttttgctt
    17521 gattttaagc atgctttgtg ctatagtaaa tgataactaa atattccttt aaacctgtcc
    17581 cgtgaggcag gcaaggagcg cgataaagta gaagggtgaa gtctacactg tgtgcagtag
    17641 ggctcgcttg gctataaatt tcaagtctcc ttgtttaagg agacttttct ttttggaggt
    17701 ttgtcatgaa aacaaaagaa gttgtagacg aattgaccgt caaacgagcg attacgcgta
    17761 ttacttatga gattatcgaa cgcaacaaag atttgaataa gatcgtcttg gctggtatta
    17821 aaactcgtgg tgtctttatt gcccaccgaa tccaagaacg tttgaagcag ttagaaaatc
    17881 tttcagttcc tgttgtggaa ttggatacta aacctttccg tgatgatgtt aaaagtggag
    17941 aagatacttc tttggtttct gtcgatgtga cagaccgcga agttatcttg gtggatgatg
    18001 tgctctatac aggtcgtacc atccgtgctg ctattgataa tattgtcggt catggtcgtc
    18061 ctgcgcgtgt gagtttagca gttctagtcg atcgtggaca tagagaattg ccaatccgtc
    18121 cagattacgt tggaaaaaat atcccaacca gtcgttctga agaaatcatc gtagagatga
    18181 cagaacttga tgaccaagac agagttctga ttactgaaga agcttagaaa gttaaaggag
    18241 tagccatgtc agaaaatcaa caagcattga accatgtggt gtccatggaa gacctcactg
    18301 tcgatcaagt aatgaaattg atcaagcgag gaattgagtt taaaaatgga gcccagcttc
    18361 cctatgaaga ccatccgatt gtttccaatc tcttctttga ggattctaca cggacacata
    18421 agtcctttga agtcgcagag attaaacttg gattggaacg acttgacttt gatgtgaaga
    18481 ctagttcggt taataagggt gagacacttt atgacaccat tttgactctg tctgctttag
    18541 gagtggatgt ctgtgtgatt cgccatccag aggtcgacta ctatagagaa ttgattgcta
    18601 gtccaacgat tacgacttcc atcatcaatg gtggagatgg ttcgggccaa caccctagcc
    18661 agagcttgct tgatttgatg accatttatg aggaatttgg ccactttgag ggtcttaaag
    18721 ttgctattgc aggtgacttg gatcactcac gcgttgccaa atccaatatg cagattttga
    18781 aacgcttggg agctgaactc tttttcgctg gacctgagga atggagaagt caagagtttg
    18841 cagactatgg acagtttgta accattgatg aaatcattga tcaggttgat gtcatgatgt
    18901 ttctccgtgt gcaacacgaa cgccatgata gtggagctgt attttcaaaa gaagactacc
    18961 atgcccaaca tggcttgact caagaacgtt acgatcgttt gaaagaaaca gcaatcctca
    19021 tgcacccagc tccaatcaat cgtgatgtag aaatagcaga ccacttggtt gaagcaccaa
    19081 aatcacggat tgtccaacaa atgaccaatg gtgtctttgt tcgaatggca atcttagaat
    19141 ccgtactagc gagtagaaac gccaactaaa acacaagacg ttaaaagacg ccagtgagcg
    19201 tccacgagag gtgaaaatat gacaaaaaga attctagtat tagaagatgg cacagttttt
    19261 gaaggcaagg ccttcggagc agatattgat gtaacaggcg aaatcgtctt taatacaggg
    19321 atgaccggct accaagaatc cattacagac cagtcttata atggacaaat cttgaccttt
    19381 acttatcctt tggtaggaaa ttatggtatt aatcgtgatg attatgaatc cattattcca
    19441 acttgtaagg gagtcgttgt ttttgaagaa gcgcgtagag ctagcaactg gcgcaaccaa
    19501 atgaccttgg atgaattttt gaaagccaag aaaattccag ggatttcagg aattgatacg
    19561 cgtgctctta ccaagattat ccgtaagcat ggtactatgc gtgcaacctt gacccatgtt
    19621 ggggacagta tggaccatgt gacggaccag ctccaagcaa cagttttacc gacagacaat
    19681 atcaaacagg tttctactaa aacgtcttat ccagctccag gagttggttt gagcgtggtg
    19741 ctagtggact ttggtctcaa gcactcaatc ctacgtgaac tttctaaacg caactgtaac
    19801 gtgacagttg ttccttattc gacaacggct gaagaaattc tccatctcaa tcctgatgga
    19861 gttatgttgt caaatggtcc aggtaaccca gaagacgttc cacaagcact cgacatgatt
    19921 cgcggtgtac aaggaaaaat tccaatcttt ggtatttgta tgggacacca actctttgca
    19981 atggcaaacg gggctaagac ctataagatg aagtttggcc atcgtggatt caaccatgcg
    20041 gtacgtgaaa tcgcaacagg acgagtagac ttcaccagcc agaaccatgg ttatgcagtc
    20101 agccgcgagg atttgccaga gcacttgatt attacccacg aagaaatcaa tgacaagtca
    20161 gtggaaggtg tgcgccacag ataccaacct gctttctctg ttcaatacca cccagatgca
    20221 gctcctgggc cacacgacgc tagctaccta tttgacgagt ttatcgagat gatggaagtt
    20281 tttaaacaat caaactaaga acgagtaaaa gctcgtcgga gaatttatgt aactgaacac
    20341 ggacggaaag ctcagaattt agagaaacca acttggattg tcaatccttc cttgatttct
    20401 taaaattcaa tcgctttcta ttcgtccttt gtatcttatt taatgtcgcc ctgagaggcg
    20461 acgaatagaa aggagaagat acattgttcg cggaagtgaa cacgccctaa gaactgtgtg
    20521 aaaaagataa acatcgtctt gacgctgaag gcgtctgcgc cgagtttcct attttcactg
    20581 tgttctttac gggctttgta tcataaacta tgcctaaacg tactgatatt caaaaaatta
    20641 tggtgattgg ttctggtccg attattattg gtcaggctgc tgagtttgac tacgctggga
    20701 cccaggcttg cttgtcgttg aaagaggaag gttatgaggt tgttttggtt aactcaaatc
    20761 ctgcaaccat catgacggac aaggaaattg ctgacaaggt ttacattgaa ccgattacac
    20821 ttgagtttgt gacacgtatt cttcgtaagg aacgtccaga tgccttgcta ccaacactcg
    20881 gtggtcagac aggtctcaac atggccatgg aattatctaa aaatggtatc ctagacgagc
    20941 ttggcgttga acttctgggt accaaattat ctgccattga ccaagcggag gaccgtgacc
    21001 tctttaaaca attgatggaa gagcttgagc aacccattcc agaatctgaa attgttaaca
    21061 cagtagaaga agcagttgcc tttgcagcga caattggcta cccagtcatc gttcgtccag
    21121 cctttaccct tggtggtact ggtggtggta tgtgtgccaa cgaaaaagaa ttgcgtgaaa
    21181 tcactgaaaa tggtttgaaa ttgtcacctg ttacccaatg tttgattgag cgttcgattg
    21241 ccggttttaa ggaaattgaa tacgaagtga tgcgtgactc agctgacaat gccttggttg
    21301 tttgtaacat ggaaaacttt gacccagttg ggattcacac aggggattcc attgtatttg
    21361 cccctgcgca aaccatgtca gactatgaaa accaaatgct tcgtgatgcg agcttgagca
    21421 ttattcgcgc cctcaagatt gaaggtggat gtaatgttca gctagctctt gatcctaaca
    21481 gcttcaagta ttatgttatc gaagtaaacc ctcgtgtatc acgttcgtca gcccttgctt
    21541 ctaaagcgac aggatatccg attgctaagt tggctgccaa gattgcagta ggtttgacct
    21601 tggatgaggt tataaaccca gttacaggtt caacctatgc catgtttgaa ccagcccttg
    21661 actacgtagt tgctaagatt ccacgtttcc catttgacaa gtttgaaaag ggtgaacgcc
    21721 gtctcggtac acaaatgaag gcgactggag aagtcatggc aatcggtcgt aacatcgagg
    21781 aatctcttct caaggcctgc cgctcccttg aaattggggt gcaccacaat gaaatacctg
    21841 aacttgcagc agtttctgat gatgccttga ttgaaaaggt tgtcaaagcc caagatgacc
    21901 gtctcttcta cgtatcagaa gccattcgtc gtggctacac acctgaagaa attgcagagc
    21961 ttacaaaaat tgatatcttc tatcttgata aactcttgca tatctttgaa attgagcaag
    22021 aattgggtgc tcatccacaa gatctagaag ttttgaaaac agccaaactt aatggtttct
    22081 cagaccgtaa gattgctgaa ctctggggaa cgactgatga tcaagttcgc caacttcgct
    22141 tggaaaacaa gattgttcca gtttataaga tggtagatac ttgtgcggca gagttcgact
    22201 ctgaaacgcc atatttctat tcaacctatg gttgggaaaa tgaatctatc agatctgata
    22261 aagaatctgt acttgtccta ggttcaggtc caatccgtat cggtcaaggg gttgagtttg
    22321 actacgcaac cgttcactct gttaaggcta tccaggcagc tggttatgaa gctatcatca
    22381 tgaactcaaa cccagagacc gtttcaacag acttctctgt atcagataag ctttactttg
    22441 agccattgac attcgaagat gttatgaacg tcattgactt ggaacaacca aagggagtta
    22501 tcgttcagtt tggtggtcaa acagccatca accttgcgga gccattggca aaagcaggtg
    22561 tgaccatcct tggtacacag gttgctgacc tagaccgtgc cgaagaccgt gacctcttcg
    22621 agcaagctct caaagaattg gatattccac agccaccagg acaaacggct accaatgaag
    22681 aagaagcagc tcttgcagct cgtaagattg gcttcccagt tcttgtccgc ccatcttatg
    22741 tacttggtgg acgtgccatg gaaatcgttg aaaacgaaga agaccttcgt tcttacatgc
    22801 gaactgctgt taaggctagt ccagatcacc cagttcttgt cgactcttat atcgttgggc
    22861 aagagtgcga agttgatgcc atttcagatg gtaaagatgt gctcattcct ggtatcatgg
    22921 agcatatcga acgtgctggt gtccactcag gtgactcaat ggctgtttac ccaccacaaa
    22981 ccttgtcgca aaaggttcag gagaccatcg cagactacac caaacgctta gcaatcggtc
    23041 ttcactgcct tggaatgatg aacatccagt ttgttatcaa ggatgaaaaa gtctacgtta
    23101 ttgaggtcaa tccacgtgcc agccgtactg ttccattcct atctaaggta accaatattc
    23161 ctatggctca agtagcgacc aagctcattc ttggtcaaag tttatcagaa cttggctacc
    23221 aaaatggact ttaccctgaa agcacccgtg ttcatatcaa ggcacctgtc ttctccttta
    23281 ccaaactagc taaggtagac agcttgctcg gtcctgaaat gaagtcaaca ggtgaagtta
    23341 tgggttctga tgctactttg gaaaaagctc tctataaagc ctttgaagct tcttatctac
    23401 acttgccaac ttttggtaat gtcgtcttta ccatcgctga tgatgccaaa gaagaagcct
    23461 tgaacttggc tcgtcgtttc caaaacattg gttatggaat ccttgcgaca gaagggacag
    23521 cagccttctt tgctagtcat ggcttgcaag cccaacctgt tggtaagatt ggtgatgacg
    23581 ataaggatat cccaagtttt gtacgcaaag gaagaattca agctatcatt aacacagtag
    23641 gaacaaaacg aactgctgac gaagatggtg agcaaattcg tcgttcagcc attgaacacg
    23701 gggtgcccct cttcacagcg ctagatacag ctaatgccat gcttaaggta cttgaaagtc
    23761 gtagctttgt tacagaagcg atttaaatag aaaaataaga tatagcagac tgaatttaga
    23821 acagtacaca ggaatactaa aatatttcta taaattaatt tgaattttct aattgatttg
    23881 ttcgcatctt atttcaatct actatagaaa aaagtcttta aaattataaa acgcatcata
    23941 tcaaggtttt tcaaaaacct tgatatgatg cgttttattg tgggaatatg tatttcattt
    24001 tctactaaaa ttatgttttt gaataacctc tatcttagta gtttgtataa tccccctcaa
    24061 tcagtttttg cgataagctt taatgctatg actataccac tcttgcattt cttttgatgg
    24121 tggtgtcata taatcgccat acatctgggt taaaaattgg tcatattttt tgggaacagg
    24181 caacatacgg ccctcaaact cagttaaaat cagttcttta aaggtatcaa ctgggaagat
    24241 ttctttcatc ccttccttac cgatcccaac tcctccttca tattgaggaa tgttggttac
    24301 agcatttttg actagttgat caattttctt gtaaaagtag cgaggattga caaatcggag
    24361 agcgtaccag ctacataatc taagaaaatc ttttagtttg ctatcaccgt gaactgctcg
    24421 tgattttttg atataagcta gttgacgaag agccacatac ttatagctct tgtcgacaat
    24481 gctcaagtct gtaaatcgat caattgggaa gacatcgatg aaaaggctgg tatcatgacg
    24541 cttgtactta acatggtctt ctataacagt agaagtgtcc aaaatcgatg cgaaattatg
    24601 gaagtaccaa gaagatgtat cgtaggaaag aaccttgtag cgagggtgat tttcttcttc
    24661 aataatcttc agtaaacgct cataatcctc acgataaagg gaaatatcaa tatcatcatc
    24721 ccaaggaatc atacctttgt ggcggatggc tccaagcatg gttccataac tgagaaaata
    24781 aggaatatca tgtttcttac aagtctcatc aatatagtcc agcagggcta gttgaatttc
    24841 tttaatttct tttttttcta aatattgcat cctaatcctc caatttataa gcgtgaaatt
    24901 catgactgta gaagcgtttt tcttctggtg gtagggtcat ataatctcca taaaattgtg
    24961 tcaaaatagt atcaaatttt tcaggtgcag gaaggcttaa attctcaaag ggtaaatcga
    25021 ttgttttatc aaaggtacca cttgggaaga cttccttttc cttaaatttt gaagggataa
    25081 aagccatata ctgcccattt tcacgactat atttttgaat ttctttctcg attttatttg
    25141 caaaataacg aggagaaact ggtcgaagga gcaaccaaaa ggctgttcgt atccaatctt
    25201 ttaaaaggct atccttatag acaatatttt tatgtttact gaaagacagc agtttgaagc
    25261 tttccagttt ataacaagta tcaatgacct taggatcatc aaagcgatcc atagggaaaa
    25321 tatcgataaa gataccagac tcataggttt ttgtatttcg agtatcaata attttagtcg
    25381 tactgtcggt tatcttgata aagttgttaa agtagttctt atcagtttct aaggatagga
    25441 gttcatactt gcttttttcc ttttgaaaaa tgttaataaa tcgttggtag tcttctctag
    25501 gcatggataa atcaatatcg tcgtcccaag ggataaagcc ctcatgtcga accgccccaa
    25561 tcagagtacc gtagttaata atatagttga tattgtgctt tttacagaga gtatcaatat
    25621 aatccaaaat ttctaattca atttgtttgg catcttcaac ggttagttgt ttcattttaa
    25681 actcctatga ttttttaaat ttatttttta aggctagaac atggtttaaa aattcataga
    25741 aaatgctatc ttttgtgaag acaagtagac taatataaga gatagctgat agcaagataa
    25801 tcaaaccagt attaatcaaa aatggcaaat taatgaccat atccacagga tacacgaaat
    25861 taatcaggaa ataaattgct acaaaggaaa gtgaaaagag agagtatcga acagtatagc
    25921 taaagatatg tcccaagtgg atgagttgtt ttctatggat gaaaatgata tagaaaacaa
    25981 gtagagaagc ctctgataac atagttgtca gtaagtagta ttcgggagcc acgatacggt
    26041 tgaaaaagag gagactattc aagcccaaat tgagtagccc agcaaagact gtataaactg
    26101 tgatacgttt ttcatagcca ttggtaaaga gaatttggga accaagaatg gtatctaagg
    26161 ccaggataat cgtacgaaaa gcgaagagag aggtcaagat gccgcctccg atatattttt
    26221 cactaccgta aagtaggatg gcatttggtc ctaaaaccat gagtccaaaa ctcagtggaa
    26281 tgataaagaa gttaaagatt cgactacctc tattaaccag agaaacatag gcttctttgt
    26341 ctcctttccc cagatagtaa ctgagacgag gcacactcac tccaattgca cctgttacaa
    26401 ccccagctat aacggtcaca attcgctgag ctatggtata gtaactaacg ttgacatcaa
    26461 tccctgtttt aacgaggaag aggcgatcta aaaaagtgaa gagcatattg gcattggcaa
    26521 agactaacat ggctgtcaga gggagaaaga gtggtttaaa atcacttagg tgaatcttaa
    26581 caagtttgat gtctctttta atccaaaaat aactaatcag gtagttaatc agcgtcgata
    26641 aactcatcac aagtgtatag acaacaatat cgtgttcatt tttaacaaat aagaaaatag
    26701 agaccagcat caggatacgg atgaaggcag ttttgtaaaa gagaaaactg taattttcca
    26761 gagcttcatt gacccattcg attgaaaaaa tctgggcaat gagttgaatc cccataacaa
    26821 ggtagacctt tttgatgatt ggattatcag taaagaagag aggataggct aggatataga
    26881 cagcagtggt caaaatcgta caagcgatgc acaaataaaa aagactagaa aaggttctgt
    26941 taagatcttt tttgttatcc ttgacattac tgatagccct taaaccgtag ttatagacac
    27001 cataagttgc aaagggcaag aaaaatgaca aaatagtgtc gactgagttg aagtaaccat
    27061 agtcagttcg gtccaagaca cgcgcgacat aggttccagt taggatggga aaaataatat
    27121 tcaagacacg aattcccatg taagatagag catttaattt tatacttttc attcaattta
    27181 cctcgttttt cattatatca taaagttagc taataagaaa tgaagggcag taagtcaagt
    27241 aatcactttg aagtttcaaa tcttaagttt taagttttct ttaaggaaag tatattattc
    27301 tgaaggactc taaaatttcg cagccattta ttagtaattg ctacagaatt cctagtcatt
    27361 actagaaatg gactagtttc tttgaataat agaactgcat aattctccta ttctagaagg
    27421 ggaggaccag tatttctttt atgataggac tagattgtgg tataatagag agaataagtt
    27481 tttttagtaa gacaaaggag aaaatagatg atttatgcag gaattcttgc cggtggaact
    27541 ggcacacgca tggggatcag taacttgcca aaacaatttt tagagctagg tgatcgacct
    27601 attttgattc atacaattga aaaatttgtc ttggagccaa gtattgaaaa aattgtagtt
    27661 ggtgttcatg gagactgggt ttctcatgca gaagatcttg tagataaata tcttcctctt
    27721 tataaggaac gtatcatcat tacaaagggt ggtgctgacc gcaatacaag tattaagaac
    27781 atcattgaag ccattgatgc ttatcgtccg cttactccag aggatatcgt tgttacccac
    27841 gattctgttc gtccatttat tacacttcgc atgattcagg acaatatcca acttgcccaa
    27901 aatcatgacg cagtggacac agtggtagaa gcggttgata ctatcgttga aagtaccaat
    27961 ggtcaattta ttacagatat tccaaatcgt gctcaccttt atcaaggaca aacacctcaa
    28021 acattccgtt gcaaggactt catggacctt tatggatctc tttctgatga agagaaggaa
    28081 atcttgacag atgcatgtaa aatctttgtg atcaaaggaa aagatgtggc tttggccaaa
    28141 ggtgaatact caaatctgaa gattacaacc gtaacagatt tgaagattgc aaaaagtatg
    28201 attgagaaag actagtaaaa tgattaatca aatttatcaa ctaactaagc ctaagtttat
    28261 caatgtcaaa tatcaggaag aggctattga ccaagagaat catatcctta tccgtcccaa
    28321 ctacatggct gtctgtcatg cggatcagcg ttactatcag ggaaaacgtg atcccaagat
    28381 tttgaataaa aagcttccaa tggcaatgat tcacgagtca tgtggaaccg tcatttctga
    28441 cccgaccgga acctacgagg ttggtcaaaa agttgtcatg attcccaatc agtctcctat
    28501 gcagagtgat gaagaattct atgaaaacta catgacaggg acccatttct tgtctagtgg
    28561 atttgatggc tttatgagag agtttgtttc tctccctaaa gatcgtgtgg tggcttatga
    28621 tgctattgaa gatacggttg cagccattac agagtttgtc agtgtgggca tgcacgctat
    28681 gaatcgtcta ttgactcttg ctcatagcaa gcgggagcgg atcgccgtta ttggagatgg
    28741 aagtttagct tttgtggttg ccaatattat caactatact ttgccagaag cagagattgt
    28801 ggttattggt cgtcattggg aaaagttgga actcttctca tttgccaaag aatgctatat
    28861 tacggataat attcctgaag atttggcctt tgaccatgct tttgaatgtt gtggtggtga
    28921 tggtactgga ccagctatta atgacttgat tcgctacatt cgtcctcagg gaacgattct
    28981 catgatggga gttagcgaat ataaagtcaa tctcaatact cgcgatgcct tagaaaaggg
    29041 cttgctcttg gttgggtcat ctcgttctgg tcgcattgat tttgaaaatg ctatccaaat
    29101 gatggaagtc aagaaatttg ccaatcgtct taaaaatatc ctttatctag aagaacctgt
    29161 aagagaaatt aaagatattc atcgtgtctt tgcaaccgat ttaaacacag cctttaaaac
    29221 agtgtttaag tgggaagtat aagtactgga ggttaattgt ggagaaaatc attaaagaaa
    29281 aaatttcttc cttacttagt caagaagagg aagtcctcag tgttgaacaa ctgggtggaa
    29341 tgaccaatca aaactatttg gccaaaacaa caaataagca atacattgtt aaattctttg
    29401 gtaaagggac agaaaagctt atcaatcgac aagatgaaaa gtacaatctt gaactactaa
    29461 aggatttagg cttagatgta aaaaattatc tttttgatat tgaagctggt atcaaagtaa
    29521 atgagtatat cggatctgcg attacgcttg attcaacgtc aatcaagacc aagttcgaca
    29581 aaattgctcc aatattacaa actattcata cgtctgctaa ggaattaaga ggagaatttg
    29641 ctccttttga agaaatcaaa aaatacgaat ccttgattga agaacaaatt ccttatgcca
    29701 actatgaatc tgttagaaat gcagtcttct ccttagagaa aagactggct gacttaggtg
    29761 ttgacagaaa atcttgtcat atcgatttgg tgcctgaaaa ctttatcgaa tcacctcaag
    29821 gacgacttta tttgattgac tgggaatatt catcaatgaa tgatccaatg tgggatttgg
    29881 ctgccctctt tttagagtct gaattcactt cccaagagga agaaactttc ttatctcact
    29941 atgagagtga gcaaacaccg gtttctcatg aaaagattgc tatttataaa attttacaag
    30001 atactatttg gagtctatgg actgtatata aggaagagca aggtgcagat tttggtgact
    30061 atggtgtgaa tcgttaccaa agagctgtta aaggtttggc ttcttatgga ggatcagatg
    30121 aaaagtaaaa acggagttcc ttttggcctt ctctcaggta ttttctgggg cttgggtcta
    30181 acggttagtg cttatatctt ttcgattttt acagatttgt caccctttgt ggtggctgca
    30241 actcatgatt ttttgagcat ctttatctta ctagcttttc tcttggtaaa agaagggaaa
    30301 gttcgcctct caattttctt aaatattcgc aatgtcagtg ttatcatcgg agccttgcta
    30361 gcaggcccta tcggtatgca ggccaatctt tatgcagtta agtatatcgg aagttcttta
    30421 gcttcatctg tatcggctat ttaccctgcg atttcagttc tattggcttt cttctttttg
    30481 aagcacaaga tttcgaaaaa tactgtattt gggattgtct tgattattgg agggattatt
    30541 gctcagacct ataaggttga acaggttaat tctttctaca ttgggattct ttgtgctttg
    30601 gtttgtgcta ttgcatgggg aagtgagagt gttcttagct cttttgccat ggaaagtgaa
    30661 ttgagtgaaa tcgaagccct cttaatccgt caagtaactt cgttcttgtc ctatcttgtg
    30721 attgtgctct tctctcatca gtcatttact gcagtagcca atggacaatt gctaggtctc
    30781 atgattgttt ttgcagcctt tgatatgatt tcctacttgg cttattatat cgctatcaat
    30841 cgcttgcaac cagccaaggc tacaggcttg aacgtgagct atgtagtatg gacggtcttg
    30901 tttgcagttg ttttcttggg tgcaccgcta gatatgctga ccattatgac gtcacttgtc
    30961 gtcattgctg gagtttatat tattattaaa gaataaagga gattcgtgtg aaagccatta
    31021 tcttagcagc gggattggga actcgcttgc gtcctatgac tgaaaatacc cctaaagcct
    31081 tggttcaggt taatcaaaaa cctttgattg agtaccaaat tgagtttctc aaagaaaaag
    31141 gaatcaatga catcatcatc attgttggtt atcttaaaga acaattcgat tacttgaaag
    31201 agaaatacgg tgttcgtctc gttttcaatg ataaatacgc tgactacaat aacttttact
    31261 ctctctatct tgtaaaagaa gaattggcca acagctatgt tattgatgct gacaattatc
    31321 tctttaaaaa tatgttccgc aatgatttga cacgttcgac ttattttagt gtttatcgtg
    31381 aagattgtac caacgaatgg ttcttggttt atggagatga ctacaaggtt caagacatta
    31441 ttgttgatag caaggcaggt cgcatcctta gtggtgtatc cttctgggat gctccaactg
    31501 cagaaaagat tgtcagcttt atcgacaagg cttatgtaag tggtgaattt gttgatctct
    31561 attgggacaa tatggttaag gataatatca aagagctaga tgtctatgtt gaagaattag
    31621 aaggcaatag catttatgag atcgatagtg tccaagacta tcgtaaatta gaagaaattc
    31681 ttaaaaacga aaattaaaga ttccaacatc tgacaaaata gtcggatgtt ttttgatttt
    31741 ttacgaactt ttacgaatag atagatgagt agaaaaagaa atggagttat ttatgaaaat
    31801 cacaaactat gaaatctata agttaaaaaa atcaggtttg accaatcaac agattttgaa
    31861 agtgctagaa tacggtgaaa atgttgatca ggagcttttg ttgggtgata ttgcagatat
    31921 ctcaggttgc cgtaatccag ccgtttttat ggaacgttat tttcagatag acgatgcgca
    31981 tttgtcgaaa gagtttcaaa aatttccatc tttctctatt ttagatgact gttatccttg
    32041 ggatttgagt gaaatatatg atgcgcctgt acttttattt tacaagggaa atcttgacct
    32101 cctgaaattc ccgaaggtag cggtcgtggg cagtcgtgct tgtagcaaac agggagctaa
    32161 gtcagttgaa aaagtcattc aaggcttgga aaatgaactg gttattgtca gtggtctggc
    32221 caagggcatt gacacagcag ctcatatggc agctcttcag aatggcggaa aaaccattgc
    32281 agtgattgga acaggactgg atgtgtttta tcctaaagcc aataaacgct tgcaagacta
    32341 catcggcaat gaccatctgg ttctaagtga atatggacct ggtgaacaac ctctgaaatt
    32401 tcattttcct gcccgtaatc gcatcattgc tggactttgt cgtggtgtga ttgtagcaga
    32461 ggctaagatg cgttcaggta gtctcattac gtgtgagcga gcaatggaag aaggacgcga
    32521 tgtctttgct attcctggta gcattttaga tggactatca gacggttgcc atcatttgat
    32581 tcaagaagga gcaaaattag tcaccagtgg gcaagatgtt cttgcggaat ttgaatttta
    32641 aaaatgacct aagctagaat tctaagaaaa aatcaatttt aagagaaaat gaacccaaca
    32701 tttccataat aaaacgcata ttagcaagtt tttaacactt gataatatgc gttttttcta
    32761 agtggattag tagagtagag gatttttctc atataatact cttcgaaaat ctcttcaaac
    32821 tacgtcagct tccatctgca acctcaaaac agtattttga gctgacttcg tcagtcttat
    32881 ctacaacctc aaagcagtgc tttgagcaac ctgtggctag cttcctagtt tgcgctttga
    32941 ttttcattga gtataaggga aagtatagtg aattgaaata agatgtgaac aactctatca
    33001 ggaaagtcaa attgatttat agaaatattt tagcagccaa ggtgcactgt tatagattca
    33061 atacactata atttagtgta attgagaaag gagaaatgat tgtgattgat gttggctagg
    33121 ttatgttcaa tgattcctac cgtctcaaat cttgtcagta aggaaaaata aattcttcaa
    33181 aagtagagat tacaaggctt gtttaagaaa gaattcaaag accttgacaa ataaaaataa
    33241 aatggttatt ataaaaaatg gtctgaaata gatgatgata cttttcgaaa atctcttcaa
    33301 actacgtcag ctcagctttg ccttgctgtg ttttgagcaa gctacggtta gcttccgagt
    33361 ttgattttca tttactagaa atgaaactga tgagagatat cagtagacat ttgagtcagg
    33421 atattatgga aaatgataaa aagagctcgt gagattggca tatcagacta ctaaagtatt
    33481 gagtttgtta ggattttagc gactagttag ctgggaaagg aagatatttg tgacaaataa
    33541 taaactgtat tcgttgatag aatttagaaa taaaatatat gaagaattag aactttccag
    33601 aagtgattta gcgattttac tatgtgccat gcttatcgcc tctatcggat taaatatgga
    33661 ttcgactccc gtgattattg gagccatgtt aatctctcct ttgatgacac ctattctggg
    33721 agtggggctc tctctagcta tatttgattt taaattgtta agaaaatctt ttaaaatatt
    33781 agctattcaa attcttgcca gtctaatagc ttcaacactt tatttttatc tttctcccat
    33841 ttcgtatgct agttcggaga ttgttgctag aacctctccg actatttggg atgttctcat
    33901 tgcttttgta ggagggatag caggtattat tggtgctagg aaaaaagaga ccaataatat
    33961 tgttcctggt gttgctattg caaccgcctt gatgcctcct ctttgtacag taggttatgc
    34021 tattgcttct gctaatctaa aatttatcat aggctcctct tacctattcc tcatcaattg
    34081 tagctttatt gtcattgcga cttatatagg tgttaggttg atgatggtta agaaacatta
    34141 ttttaaagat aatgaagaag actctaaaat gcgtaggatt ttgcttctag ttgctgtttt
    34201 gctgatgatt ccgagtttca tctctgcaac gactttagtg agagaaacgt tgaaaaaaga
    34261 gtcccttaag aaatttatat cagagcagtt tcaggagtat aatattttga aaaaaaccta
    34321 ttctaaaaag actcataccc taaagctaac catttcagga aattatttga cagaagaaga
    34381 actcgatatg atttcaagta agagaggtga ctatggttta agtgatgttt ctgttcaagt
    34441 ttcacaattg tctgattcag aacaacttag taaggaagag ctggtggagt atttcttcca
    34501 gtatatcaag gataaggaag caaaagaaaa ggagaaagcc aataaatttg atacagagtc
    34561 tgaggagcaa taatttcttg agaatagctg gtttctctcg tgagtcttct atgtatatca
    34621 aaggaagact gaggttttaa gtataaaact tttcttctat tatagtagct aagtcttgac
    34681 agggttcaaa aaatggttta cactttataa agtttattac tttgaaaagg tgtgatactg
    34741 tggctacggc aacaaaaaag aaaaaatcaa cagttaaaaa aaatctagtc atcgtggagt
    34801 cgcctgctaa ggccaagacg attgaaaaat atctaggcag aaactacaag gttttagcca
    34861 gtgtcgggca tatccgtgat ttgaagaaat ccagtatgtc cgtcgatatt gaaaataatt
    34921 atgaaccgca atatattaat atccgaggaa aaggccctct tatcaatgac ttgaaaaaag
    34981 aagctaaaaa agctaataaa gtttttctcg cgagtgaccc ggaccgtgaa ggagaagcga
    35041 tttcttggca tttggcccat attctcaact tggatgaaaa tgatgccaac cgtgtggtct
    35101 tcaatgaaat caccaaggat gcagtcaaaa atgcttttaa agaacctcgt aagatcgata
    35161 tggacttggt cgatgcccaa caagctcgtc ggatcttgga tcgcttggta gggtattcga
    35221 tttcgcctat tttgtggaag aaggtcaaga agggcttgtc agcaggtcgc gttcagtcca
    35281 ttgcccttaa actcatcatt gaccgtgaaa atgaaatcaa tgccttccag ccagaagaat
    35341 actggacagt tgatgctgtc tttaaaaagg gaaccaaaca atttcatgct tccttctatg
    35401 gagtagatgg taaaaagatg aaactgacca gcaataacga agtcaaggaa gtcttgtctc
    35461 gtctgacgag taaagacttt tcagtagatc aggtggataa aaaagagcgc aagcgcaatg
    35521 ctcctttacc ctataccact tcatctatgc agatggatgc tgccaataaa atcaatttcc
    35581 gtactcgaaa aaccatgatg gttgcccaac agctctatga aggaattaat attggttctg
    35641 gtgttcaagg tttgattacc tatatgcgta ccgattcgac tcgtatcagt cctgtagcgc
    35701 aaaatgaggc ggcaagcttc attacggatc gttttggtag caagtattct aagcacggta
    35761 gcaaggtcaa aaacgcatca ggtgctcagg atgcccatga ggctattcgt ccgtcaagtg
    35821 tctttaatac accagaaagc atcgctaagt atctggacaa ggatcagctc aagctatata
    35881 cccttatctg gaatcgtttt gtggctagcc agatgacagc ggccgttttt gataccatgg
    35941 ctgttaaatt gtctcaaaat ggagttcaat ttgctgccaa tggtagtcag gttaagtttg
    36001 atggttatct tgccatttat aatgattctg acaagaataa gatgttaccg gacatggttg
    36061 ttggagatgt ggtcaaacag gtcaatagca aaccagagca acatttcacc caaccgcctg
    36121 cccgttattc tgaagcaaca ctgattaaaa ccttagagga aaatggggtt ggacgtccat
    36181 caacctatgc gccaaccatt gaaaccattc agaaacgtta ttatgttcgc ctggcagcca
    36241 aacgttttga accgacagag ttgggagaaa ttgtcaataa gctcatcgtt gaatatttcc
    36301 cagatatcgt aaacgtgacc ttcacagctg aaatggaagg taaactggat gatgtcgaag
    36361 ttggaaaaga gcagtggcga cgggtcattg atgcctttta caaaccattc tctaaagaag
    36421 ttgccaaggc tgaagaagaa atggaaaaaa tccagattaa ggatgaacca gctggatttg
    36481 actgtgaagt gtgtggcagt ccaatggtca ttaaacttgg tcgttttggt aaattctacg
    36541 cttgtagcaa tttcccagat tgccgtcata cccaagcaat cgtgaaagag attggtgttg
    36601 agtgtccaag ctgtcatcag ggacaaatta ttgagcgaaa aaccaagcgt aatcgcctct
    36661 tctatggttg caatcgctat ccagaatgtg aatttacctc ttgggacaag cctgttggtc
    36721 gtgactgtcc aaaatgtggc aacttcctca tggagaaaaa agtccgtggt ggtggcaagc
    36781 aggttgtttg tagcaaaggc gactacgagg aagaaaagat taaataagag gaggggcccg
    36841 aaagtaaatt tcaggctctt tttggttaga acttgacaaa atacatcatt ttatgcgaaa
    36901 ctagaagaag attattttaa ctaggagaag ttatgcgtct tatctatctg ataattggtt
    36961 ttttatcact ggccttggct attgttgggg ttgttttacc cttgttgcct acaacacctt
    37021 tccttttgtt gtctattgct tgtttctcca gaagttccaa gcgattcgaa gactggcttt
    37081 atcataccaa gctctatcaa acatatgtag ctgattttcg cgagactaag tctattacgc
    37141 gtgaacgaaa gaaaaaaatc atcgtatcca tttacatttt gatggggatt tctatttatt
    37201 ttgcccctct cttaccagtc aaaatcggtc tgggtgcttt gaccatcttt atcacttatt
    37261 atctcttcaa ggtcattcca gacaaagaat agttaaaaca gtagttattt accttgataa
    37321 aattgaaagc atattcataa caatatgata taataaattt gaagtaatat tcaaggagaa
    37381 tcaaatgatt tacgaatttt gtgctgaaaa tgtgacttta cttgaaaaag cgatgcaggc
    37441 tggagctcgt cggattgaac tctgtgataa tctagcagtt ggtgggacaa cacctagcta
    37501 tggagtgact aaggcagcgg ttgaactggc agctaactac gatacaacca tcatgaccat
    37561 gattcggcca cgtggtggtg actttgtcta taatgaccta gaaattgcta tcatgctaga
    37621 agacatttgt ttgactgctc aggctggaag tcaaggggtt gtatttggag ctttaactgc
    37681 tgataaaaag ttggataagc ctaatctgga aaagttaatt gctgcatcaa aaggaatgga
    37741 aattgtcttt cacatggcct ttgatgaact aagtgatgaa gatcaaccgg aagctattga
    37801 ctggctcagt caagccggtg tcactcgtat cctaactcgt gctggtgtgt ctggcgactc
    37861 cttagaaaaa cgttttgttc actatcacag aattttggag tacgctaaag gtaaaattga
    37921 aattctacca ggtgggggga ttgaccttga caaccgtcaa acctttattg accaggtggg
    37981 ggtaacacaa ttgcatggta ctaaggttgt tttttaaaaa atagaaagga actgctagcc
    38041 ttgggtagca gttttcactt atgtttgaaa tttttaaatc ctatcaattt aatcaagaaa
    38101 aggctcatga ttatggtttt atagaaaata gcgaagtctg gacatatagt tgccagattt
    38161 tgcaaggtga ctttgtcatg actgtgtcca tcactgctga taatgtgaac tttcaagtct
    38221 ttgaccaaga gactggtgac ctctatcctc acgttcatat ggaaagcatg aggggaagtt
    38281 ttgtcggaaa tgtccgtgag gcttgtctgg agattcttta ccagattcgg aaggcttgtt
    38341 ttgatgtgca agattttatc tgtcatcaga ctaagcgtat catgactcaa gttcaggaaa
    38401 agtatggaaa ccagttggag tatctgtggg aaaaatcgcc tgatacagct gtattgcgcc
    38461 atgaaggcaa tcaaaagtgg tatgccgtct tgatgaaaat ctcttggaat aagctggaaa
    38521 agggcagaga aggacaagtg gaagcagtca acctcaagca tgaccaagta gctaatttgc
    38581 tttcacaaaa ggggatttat ccagccttcc atatgagcaa gcgctactgg attagtgtgt
    38641 cccttgatga tactttatca gatgaagaag tactggaatt gatagaaaaa agttggaact
    38701 taacctctaa aaaatgaaat attttaataa ttttcatgaa ctttcaatta gctaaatatt
    38761 ctttactgaa gaaattttta gaaaatatag gatttaccac actagaggaa tatggtgcca
    38821 tcttcaaata cctgattgag aatgtcaaga cggatcgtca gatcatctgt tcgcctcact
    38881 gtcatgatga cctcggaatg gcagtggcaa atagccttgc tgctgtcaag aatggtgcag
    38941 gacgtgttga agggactatc aatggtatta gggagcgagc tgaaaatgct gctttggaag
    39001 aaattgcagt ggctctcaat attcgccaag attactacca agtagaaacc agtattgtcc
    39061 taaatgagac catcaatacg tcagaaatgg tttctcgctt ctctggtatt ccagttccta
    39121 aaaacaaagc cgtcgttggt ggcaatacct tctcccacga atctggtatt caccaagatg
    39181 gagtccttaa aaatcctctc acttatgaga tcatcacacc tgaattggtt ggtgttaaga
    39241 ttccgcttgg aaaattatct ggtcgccatg cttttgttga gaaactgaga gaattggccc
    39301 tagattttac agaagaggat atcaaaccac tctttgctaa gttcaaggca ctggccgata
    39361 agaagtaaga aatcacagat gcagatcctc gagctttggt agctggaacc atggttgaaa
    39421 atccagaagg cttccacttt gatgatttac aacttcaaac tcatgcagat aatgacattg
    39481 aagcgctcgt tagcctagcc aatatggatg gtgagaaagt cgaatttaat gcgacagggc
    39541 aaggttccgt tgaagcaatc tttaacgcta tcgataagtt ctttaaccaa tctgttcgtt
    39601 tggtgtccta cactatcaat gcggtaacag atggaatcga tgcccaggat cgggttttgg
    39661 tcactgttga aaacagagat acagaaacca tctttaatgc agcagggctt gattttgatg
    39721 tgttgaaggc ttctgctatt gcctatataa acgctaatac ctttgttcaa aaagagaatg
    39781 caggtgagat gggacgcagt gtttcttacc acgatatgcc tagtgtgtaa aggagaaggc
    39841 tatggcaaag aaaatagtag ctctagtagg agacggaatt ggcccagaaa tcatggaggc
    39901 tggtttagaa gttctggagg ctctagctga aaaaacaggt tttgactatg agattgacag
    39961 acgaccgttc ggaggtgcag atattgatgc agcaggacct cccttacctg atgaaaccct
    40021 taaggcaagt agggaagcag atgctatcct actagcagct atcggtagtc ctcagtatga
    40081 tggagcagcg gttcgccctg aacaaggcct gatggctctc cgtaaggaac tcaatcttta
    40141 cgctaatatt cgtcctgtaa aaatctttga cagtctcaag tatttgtcac cactcaaacc
    40201 ggaacgaatt tctggtgtag actttgtcgt ggtgcgtgaa ttgacaggcg agatttactt
    40261 tggagatcat attcttgaag agcgcaaagc gcgtgatatc aacgactata gctatgagga
    40321 agtggagcgg attattcgca aagcctttga aattgcaaga aatcgcagaa aaatcgttac
    40381 tagtatcgat aagcaaaatg ttctagcgac ctcaaaactc tggcggaaag tagctgagga
    40441 agtcgcacag gatttcccag atgtaacctt ggaacaccag ctggtagact cagctgctat
    40501 gcttatgatt accaatcctg ctaagtttga tgttattgta acggagaatc tttttggaga
    40561 tattttatct gatgaatcaa gcgtcttatc tggtacactt gaggttatgc catcagccag
    40621 tcattctgaa aatggaccaa gtctctatga acctattcac ggttcagcac ctgatattgc
    40681 aggtcaagga attgccaatc ctacttccat gattttatca gttgccatga tgttgagaga
    40741 tagtttcgga cgttatgagg atgcagagcg tatcaaacat gctgttgaga caagtctggc
    40801 ggcaggaatt ttaacgagag atataggagg tcaggcttca acaaaggaaa tgacggaagc
    40861 tattattgca aggttatgaa gttagacgaa aaaattactc tagtcctttt gatttggaat
    40921 gtcatcattt tcttgattta tggcattgac aaattcaagg caagaagaag aacttggcgc
    40981 atccaagaga aaatcttact cattttagcc cttacttgtg gtggttttgg ggcctggtta
    41041 gctggaatca cttttcacca caagactcga aaatggtact ttaaaacagt ttggtttctt
    41101 gggatggtga ccacactagt agccttatat tttatttgga ggtaatggat ggcagggtct
    41161 tcgagggaac acgctgcttg ggttctagcg gactatggtt ttaaggtcgt gattgcagga
    41221 tctttcggtg acattcatta caataatgaa ctcaataatg gcctgttgcc aatcgttcag
    41281 cctagagagg ttagagagaa actagcccag ctaaaaccaa ccgaccaggt aactgtggac
    41341 ttggaacaac aaaaaatcat ctcaccagtt gaagaattca ccttcgagat agatagcgag
    41401 tggaaacata aactcctaaa tagtttggat gatatcggta ttaccttgca gtatgaagag
    41461 ttgattgctg cttatgaaaa acaacgacca gcctactggc aggattagaa aaaatagaaa
    41521 aggaaatata gtaaactgaa ataagatgta aacaaatgaa ttagagctta acatccattt
    41581 ccagcaattt tttagaaact acagtggact attctggatt caacacatta taaaattatg
    41641 acaaaacaca ttcacaagaa ggctacgaca ttttaaaagg tgagggcgga tgtatcgttt
    41701 gccctactaa agttggttac attatcatga ccagcaacaa ggcaggactt gagcgtaagt
    41761 tcgcagccaa agaacgtaag cgtaacaaac caggtgttgt tctctgcggt agcatggatg
    41821 aacttcgcgc tttagcgcaa ctcaacccag aaattgaagc attctactaa aaacattgga
    41881 tgaagatatt cttcttggtt gtatccttcc ttggaaacca gaagcctttg aaaaactcaa
    41941 agcatacggg aatggccgtg aagaacttat gactgatgta cgtggtacta gctgttttgt
    42001 tatcaagttt ggaaaagcag gtgaacaatt ggctgccaag ctttgggaag aaggtaaaat
    42061 ggtctacgcc tcatatgctt caatgacaaa acgattgaaa ctcgctatga gagcaaggtg
    42121 taatggtgtc tatggtcgat aaggacggca aactcatccc agaacaagga ggagcacgtt
    42181 caacttcacc agcaccagtt gtgatccgta aagggcttga cattgataaa atcatgatgc
    42241 acctgtcaga tacttttaac tcatgggact accgtcaggt tgagtattat taagataaaa
    42301 aaagaagtct agtgttatga gatattaaag ctcctaacac tggacttttt gtttagaatt
    42361 tcttttcttt ttctatagga tatggtattc tatgtagaaa atatatgtta ataagtaatg
    42421 ccaatattta aacatcatta gtaaaaggag ttagattgat gaataaaaga aaagttagtt
    42481 tagaagattt ttataaatgg tatagtctaa ataaagaaga gttattaaat aaggcaactg
    42541 ttggtgaaaa gtttaatgat aaattaaaag aagagtttct ccaggaatgg cctttggata
    42601 ggattttaac aatgtcaatc gatgaatatg taataggaaa gggacagcaa aataagtctt
    42661 tatgctacgc tcttgagaag ggaaaataca aaaatctatt tcttggaatt tctggtggct
    42721 cagcttcaaa atttggtatt tattggaata aaaaaacaaa caaatataaa gatcaagcta
    42781 ataatgagat ttcagagttg gatcagcgat tttcaaaatt aaaatcagat ttgtatgaaa
    42841 ttatcaaaga aggtattcgt tttaactttg aaaatcctat ttttgatatg aaaagatcaa
    42901 caaatgaatt tattggtcgt tctgctatgg tgacaaaatt actttgtatc tatactgagg
    42961 gagatccttt ctttggtgta aatattaata gtcagaaaga attttggaac cactttgttt
    43021 ctcagacaaa tcaaggtgga ccttatctgc aaaatcataa aataattgaa ctagtgtcca
    43081 aaacttatcc tgagttggag ccatcgaaat taggaactat gctttttgag tattctaagc
    43141 tttttatgga aaataaggaa gacaatagta caatggattc atcaaacaat tttcgtcatc
    43201 aattaactca atctctatta aagtctccaa acctcatcct ccgtggtgct cctggcacag
    43261 gaaagactta tcttgctaaa gaaattgcca aagaattaac ggatggcaac gaagaccaaa
    43321 tcggatttgt acaatttcac ccatcctatg attatacgga ttttgtagaa ggtttaagac
    43381 cagtatcaaa tggggatgga gctattgagt ttaggctaca ggacggtatt tttaaagatt
    43441 tttgtcagaa agcaaaagaa acccaattga ttggaggaca agataatttt gatgaggctt
    43501 gggattctta cttagaatat ataaatgttg ctgaagaaaa agaatatata acaaaaacat
    43561 cttacttatc tattaatagt agacaaaatt tgtcagtaaa ttatgatagt ggtgtttcag
    43621 gatggtcact acctagcaaa tatgtttacg agttgtataa agataaaaat tataataagc
    43681 aagaatacta caaaagtggt ggaaaaactg tcctagaaac attgagaaag agatttggtt
    43741 tgaaagacta tgtttcccca acagaaattg atactgataa gaaattcgtc ttcatcatcg
    43801 atgaaatcaa tcgtggggag atttctaaga tttttggcga actctttttc tctatcgacc
    43861 ctggctatcg tggtgaaaaa ggaagtgttt ctacccaata tgcaaatcta cacgaaactg
    43921 atgaaaagtt ctatatcccc gaaaatgttt acatcatcgg aactatgaat gatattgatc
    43981 gttcagtgga tacctttgat tttgctatgc gtcgtcgttt tcgttttgtt gaagttactg
    44041 ccgagggtca agttggcatg ttggataaag agctgaatat ccatgcagaa gaagcaaaaa
    44101 ttcgtctaag aaacttgaac gctgctatcg aaaatgttca ggaattaaac agtcattatc
    44161 atattggacc aagttatttt cttaagttga aggatgtaga ttttgactat gaattactct
    44221 ggtctgatta tattaagcct ctcctagaag actacttgcg aggttcttat gatgaggttg
    44281 aaactttgga aactttgaaa aaagcatttg aactgacaaa taatgatcaa actggtcaac
    44341 aagatactgg tgataatgat gcggattact gataatcaat acaagattat taaagaaaaa
    44401 tttgttgaag aatatcctaa actaagcaat cttcttttag acagaacctt ggaaagtcta
    44461 tcccaagatg aacgtatttt catttttcca aatgatttga ctcatactcc tgatttggat
    44521 aaggaccaaa agatttttga aacagtcaat cagaaaatca agacagggaa cgtgattggt
    44581 tttcttggat atggtcagga aagattaacg atttcctcac gattttctga tgagagtaat
    44641 gaccattttt tgcattatct cttaaacaag gttcttcata tcaatctcac tagtttagat
    44701 gttgctttgt ctcgtgaaga gaggctttat caacttttga tgtatctctt ccccaagtat
    44761 ctacaagctg ctattcgaaa aggtctttat aaggaatacc agagattttc tcataacgac
    44821 agtcatgtta agggagtgat tgatgtaaga aaccatctca agaaaaatct tcctttcacg
    44881 ggaaatattg cctacacaac gagagagttc acctatgata atcccctcat gcagttggtc
    44941 cgtcacacta ttgaatacat taagaatcag aaaagcattg gtcaaggggt actagataat
    45001 ctctcaacta gtcgtgaaaa cgtatctgaa atcgtgcgtg taacgccctc ttataaacta
    45061 gctgatcgtg ctaagattat tcggggaaat caatctaaac ctatacgtca tgcatacttt
    45121 cacgagtaca gaaacttaca agaactttgt ctgatgatcc taaaccaaga aaagcacggt
    45181 ttagggtatc aagatcaaaa aatctatggt attctctttg atgttgcctg gctttgggaa
    45241 gagtatgttt acaccttgtt gccaaaaggt tttgtacatc ccagaaataa ggataagacg
    45301 gatggaattt cagtattttc tgttgggaaa cgaaaagtat atccagattt ttatgacaga
    45361 gaacgaaaga ttgttctaga tgcaaaatat aaaaaactgg aattgactga aaaaggaatc
    45421 aaccgtgagg acttattcca gctgatttcc tattcttata ttttaaaagc tgagaaggct
    45481 ggacttgttt ttccgagcaa ggacaaggtt attgataatg agatgggaaa cctagcaggt
    45541 tatggagctt tgttgaagaa atggtctatc caaattcctc agaagtcttc atcttatagt
    45601 gcattttgta aaatgatgga aaattcagaa gaaaatttta aagcgattat tgatgaagaa
    45661 gtggggagaa aataatttcc tctctttctt ttatttttaa cacaagtaaa acccgaacaa
    45721 tatatttcaa ttcataaaat aatttgacaa aaactgtact ttggtttata ataaattaag
    45781 gaaacgtcgg aaaagacgta gtgatgcgag agcataggta ggtcattaca aaagaaacga
    45841 gacatcgata tgttaaatga atttccaatt tttgattacg aagatattca attgattcca
    45901 aataaatgtg tcattaaaag ccgtgcagaa gcggatacaa gtgtcacttt aggaaatcac
    45961 acctttaaac tacctgttgt gccagcgaat atgcagacga ttttggatga aaatgtagca
    46021 gagcaactgg ctaaaggtgg ttacttctac attatgcacc gttttgatga ggcaggacgc
    46081 attcctttta ttaaacgaat gcacgatcaa gggctcattg cttctatctc tgtcggtgtt
    46141 aaggactatg agtatgattt cgttagacag ctcaagactg atgctcctga gtatatcact
    46201 attgatattg ctcatggtca tgcggatagc gtgatttcta tgattcaaca catcaagaaa
    46261 gaattgccag atacctttgt cattgctgga aatgtgggaa caccagaagc tgtgcgtgaa
    46321 ttggaaaatg ctggtgcgga tgctactaag gtcggaatcg gtcctggtaa ggtttgtatc
    46381 accaaggtta agactggttt tggtacaggt ggttggcagt tggctgctct acgctggtgt
    46441 gccaaggctg cgcgtaaacc gattatcgct gatggaggaa ttcgtactca cggtgatatt
    46501 gccaagtcta tccgcttcgg tgctagcatg atcatgattg gttccctctt tgcaggacac
    46561 attgaaagtc cagggaaaac gattgaagtc gatggtgaac agttcaaaga atattatggt
    46621 tcagcctcac aatatcagaa aggtgcttac aaaaatgtgg aaggcaaacg tatcttgctt
    46681 cctgctaaag gtcatctgca agacacttta actgagatgg aacaagacct tcaaagtgct
    46741 atttcttatg caggtggacg tcaggttgct gaccttaaac acgttgatta tgtgatcgtg
    46801 aaaaactcaa tctggaatgg ggatgcttcc cactaagacg gggtctttga ctaaaaaact
    46861 tgttattaga gcaaatttct gttataataa aacaagtttc cacccttagt gtaatggata
    46921 tcacgtaaga ttccggttct tgagatgggg gttcgattcc ctcagggtgg atgtaaacat
    46981 cctaaaaagc ctttaatagg gcttttttct ttacactgct ctaaatttgc cgctaaaact
    47041 gagaatctct gtctaaagaa ttcccaaatg ctttccagtc ccgttttaga gtgactcagg
    47101 gggctttttt tgatataata aaaaggactg ttatcagtta gaaagaggtt ggtatgaaag
    47161 aattacaaac tgtactaaag aaccattttg caatcgaatt tacagacaaa aatttactgg
    47221 aaactgcctt tactcatacg agttatgcca atgagcaccg cctcttaaaa atttcacaca
    47281 atgaacgctt ggaattttta ggagacgctg ttctacagtt attgatttca gaatatctgt
    47341 ataaaaaata tcctaaaaag cctgaaggtg acctatcaaa actccgtgct atgattgtcc
    47401 gtgaggagag tttagctggt tttgcgcgtg attgccagtt tgaccagttt atcaagttgg
    47461 gtaaagggga agaaaaatca ggtggtcgca atcgtgacac cattcttggt gatgcctttg
    47521 aagcctttct tggtgccctt cttttggata aggatgtggc caaggtcaag gaatttatct
    47581 atcaagtcat gattcctaag gttgaagcag gcgagtttga gatgattaca gactataaaa
    47641 cctatctcca agagttgctt caggtcaatg gtgatgtggc tattcgttat caggtgattt
    47701 ctgaaacagg gcctgctcac gataaggtct ttgatgtaga agttcttgtt gaaggtaaga
    47761 gcatcggtca aggccaaggt cgttctaaga aattagcaga gcaggaagct gccaaaaatg
    47821 ccgttgagaa ggggctggat tcatgtattt aaaggaaatc gaaattcagg ggttcaagtc
    47881 ttttgctgat aagaccaagg tcgtttttga ccaaggtgtg acggcagttg ttggacccaa
    47941 tggatctgga aagtccaata ttacagaaag tctgcgttgg gctttggggg agtctagtgt
    48001 caagagtctc cgtgggggca agatgccgga tgtcatcttt gctggaaccg aaagtcgcaa
    48061 accgctcaat tatgcttctg tagttgtgac tctggataat catgacggat ttatcaagga
    48121 tgcaggtcaa gaaatcaggg tggaacgcca tatctatcgt agtggagata gcgaatacaa
    48181 gattgacggc aagaaagtcc gtctgcgtga tattcatgac ctcttcttgg atactggatt
    48241 gggacgagat tccttctcta ttatttccca agggaaggtt gaggagattt ttaattccaa
    48301 gtctgaggaa cgacgagcta tttttgaaga agctgctgga gttttaaaat acaagactcg
    48361 cagaaaagaa accgagagta aactgcagca aactcaggat aatctggacc gcttagagga
    48421 cattatctac gagttggata atcaaatcaa gcctcttgag aagcaagctg agaatgcccg
    48481 taagttttta gacttggaag gacaacgtaa ggctatttat ttagacgttc tggttgctca
    48541 aatcaaggaa aataaggcag aactagagtc gacagaagaa gagctggctc aggttcaaga
    48601 actcttgatg agttattacc aaaagcgtga aaaattagaa gaagaaaatc aaactcttaa
    48661 aaagcaacgc caagatttac aggatgaaat ggccaaagac caaggcagtt tgatggactt
    48721 aactagtctg attagtgatt tagaaagaaa attagcccta tcgaaactgg agtccgagca
    48781 agtggccttg aatcaacagg aggcacaagc tcgtttggct gctttggagg ataagagaaa
    48841 ttcactcagc aaagaaaagt atgataaaga aagctcttta gctctgttag agggaaatct
    48901 agtccaaaat aatcaaaaac tcaatcgttt agaagctgaa ttgctggctt tctcagacga
    48961 tcctgatcag atgattgagc tcttacgtga acgctttgta gctcttttac aagaagaagc
    49021 ggatgtctca aaccagttga cccgtattga gaatgagttg gaaaatagtc gtcagctttc
    49081 tcaaaaacaa gcagatcaac tagaaaagct gaaagagcaa ttggctatag ctaaagagaa
    49141 ggctagtcag caaaaggaag agcttgaaac tgccaaggag caggttcaga aattattggc
    49201 tgactaccaa gctattgcca aggagcaaga ggagcagaaa acttcctatc aagctcaaca
    49261 aagccaactc tttgaccgtc tggataatct caaaaacaag caggccagag ctcaaagttt
    49321 ggaaaatatc ctgagaaatc atagtaactt ttatgcaggt gttaagagtg ttctccaaga
    49381 aaaagatcgc ctaggtggga ttattggtgc agtcagtgag catctgacct ttgatgttta
    49441 ttatcaaact gccctagaga ttgccttagg ggcaagtagc cagcatatca tcgtagaaga
    49501 tgaagagtcg gcaaccaagg ctattgactt ccttaaacgg aacagagccg gtcgtgcaac
    49561 ctttcttcct ttaaccacta tcaaggcgcg tacgatttct agtcagaacc aagatgctat
    49621 cgctgtaagc ccaggtttcc ttgggatggc agatgagttg gtgacttttg atactagact
    49681 ggaagccatt ttcaagaact tgctagctac gacggctatc tttgataccg tagaacatgc
    49741 gcgtgcagca gctcgccaag ttcgttatca ggttcgtatg gtgacattgg atgggacaga
    49801 attacgcacg ggtggttctt acgcaggtgg agccaatcgt cagaacaaca gtattttcat
    49861 caagccagaa ctggagcaat tacaaaaaga aattgctgaa gaagaagcaa gtttgcgttc
    49921 agatgaagtg agtttgaaga acttgcaaga tgagctagct agattgacag aaagattaga
    49981 agccatcaaa tctcagggag agcaggctcg tattcaggag caaggcttgt ccctcgccta
    50041 tcagcagacc agtcagcaag ttgaagaact ggaaactctt tggaaactcc aagaagagga
    50101 aatagatcgt ctttccgagg gagattggca agcggataag gaaaaatgcc aagagcgtct
    50161 tgctgcaatc gccagtgaca agcaaaatct ggaagctgag attgaagaga ttaagtctaa
    50221 caaaaatgcc atccaagaac gctatcaaaa cttgcaggaa gagctagcgc aagctcgttt
    50281 gcttaagaca gaactgcaag ggcaaaaacg ttatgaagtt gctgatattg aacgcttagg
    50341 caaggaattg gacaatcttg attttgaaca agaagaaatc cagcgccttc ttcaagaaaa
    50401 ggttgataat cttgagaagg ttgatacaga attgctcagt caacaggcgg aagaatccaa
    50461 aactcagaaa acaaatctcc aacaaggttt gattcgccag cagtttgagt tggatgatat
    50521 agaaggtcaa ctggatgata ttgccagtca tttggatcag gctcgccagc agaatgagga
    50581 gtggattcgc aagcaaacac gtgctgaagc caagaaagaa aaggtcagcg aacgcttgcg
    50641 ccatctacaa agtcaattaa cagaccagta ccagattagc tatactgaag ctctagaaaa
    50701 agcgcatgaa ttggaaaacc tcaatctggc agagcaagaa gttaaggatt tagagaaggc
    50761 tattcgctca ctgggtcctg tcaatataga agctattgac cagtacgaag aagttcacaa
    50821 ccgtctggac tttctaaata gtcagcgaga tgatattttg tcagcgaaaa atctgctcct
    50881 tgaaaccatt acagagatga atgatgaggt taaggaacgc tttaaatcaa cctttgaggc
    50941 cattcgtgag tcctttaaag tgaccttcaa gcagatgttt ggcggaggtc aggcagactt
    51001 gatattgact gagggcgacc ttttaacagc tggtgtggag atttctgttc aacctccagg
    51061 taagaaaatc cagtcgctta acctcatgag tggtggtgaa aaagctctat cggctcttgc
    51121 cttgctcttc tccattattc gtgtcaagac tatcccattt gtcatcttgg atgaggtaga
    51181 ggctgcgctg gacgaagcca atgttaaacg ttttggggat tacctcaacc gctttgacaa
    51241 ggacagccag ttcatcgtcg taacccatcg taagggaacc atggcagcgg ctgattctat
    51301 ctatggagtg accatgcaag aatcgggggt ctcaaaaatt gtttcggtta agttaaaaga
    51361 tttagaaagt attgaaggat gacaattaaa ctagtagcaa cggatatgga cggaaccttc
    51421 ctagatggga atgggcgctt tgatatggat cgcctcaagt ctctcttggc ttcctataag
    51481 gaaaaaggga tttactttgc ggtggcttcg ggtcggggat ttctgtctct ggaaaaatta
    51541 tttgctggtg ttcgtgatga cattattttc atcgcggaaa atggcagttt ggtagagtat
    51601 caaggtcagg acttgtatga agcgactatg tctcgtgact tttatctggc aacttttgaa
    51661 aagctgaaaa cgtcacctta tgtagatatc aataaactgc tcttgacggg taagaagggt
    51721 tcatatgttc tagatacggt tgatgagacc tatttgaaag tgagtcagca ttataatgaa
    51781 aatatccaaa aagtagcgag tttggaagat atcacagatg acattttcaa atttacaacc
    51841 aacttcacag aagaaacgct agaagctggt gaagcttggg tcaatgataa tgtccctggt
    51901 gtcaaggcta tgacaactgg ctttgaatct attgatattg ttctggacta tgtcgataag
    51961 ggtgtagcta ttgttgaatt agctaaaaaa cttggtatca caatggatca ggtcatggct
    52021 tttggagaca atcttaatga cttacatatg atgcaggttg tgggacatcc tgtagctcct
    52081 gaaaatgcac gacctgaaat tttagaatta gcaaagactg tgattggtca ccataaggaa
    52141 cggtcggtta tagcttatat ggagggctta taatggcaga tataaaattg attgcattgg
    52201 acttggacgg gaccttgctg actactgata aaaggctgac ggatcgtacc aaggaaacct
    52261 tgaaagctgc gcgtgatcgt ggtatcaagg tcgtattgac aactggtcgt cccttaaaag
    52321 ctatggattt ctttctccat gagctaggga ctgacggtca ggaagatgag tataccatta
    52381 cttttaatgg tggtttggtt cagaaaaata caggtgaaat ccttgataag acagtctttt
    52441 catatgatga tgtggcacgc ttgtatgaga aaacagagaa attatcactg ccacttgatg
    52501 ccatctcaga aggaacagtt tatcaaatcc aatcggacca agaaagtctt tatgccaaat
    52561 tcaatccagc tttgactttt gttccagttg actttgaaga cctgtctagt caaatgacct
    52621 acaacaaatg cgtgactgcc tttgctcaag aacccttgga tgcagccatt cagaagattt
    52681 ctccagaatt gtttgaccaa tatgaaatct ttaaatcacg tgaaatgttg ctagagtggt
    52741 caccaaagaa tgttcataaa gcaacaggtt tggcaaaact aatcagccat ctcggaatca
    52801 accaaagcca agttatggcc tgtggtgacg aggccaatga cctttctatg attgaatggg
    52861 caggtcttgg tgttgctatg caaaacgctg ttcctgaagt aaaggcagcc gcaaatgtag
    52921 taatgccgat gaccaacgat gaggaagctg tcgcctgggc tatcgaagaa tatgtgctaa
    52981 aggagaacta agatatggga ttgtttgacc gtctattcgg aaaaaaagaa gaacctaaaa
    53041 tcgaagaagt tgtaaaagaa gctctggaaa atcttgattt gtctgaagat gttgatccta
    53101 ccttcacaga agttgaggaa gttcctcagg aagaagcaga ggttgaaatt gttgaacaag
    53161 ctgtgttcca agaggaggaa atccaagaca cagttgaaga aagtcaggat tcagagccag
    53221 ctgtaggggt ttctcaagaa gaaatagaag aattaccaaa ctcagaagaa ttaccagagg
    53281 aagagaagct tgagcacgaa ggaactgtag aagaaaataa ttctgaagtt cttgaaccag
    53341 aaaggcctca aacagaagaa actgttcagg aaaaatatga ccgcagtctc aagaagactc
    53401 gtacgggctt cggtgctcgc ttgaacgcct tctttgctaa cttccgctct gttgacgaag
    53461 aatttttcga ggaactggaa gaactgctga ttatgagtga tgttggtgtc caagtcgctt
    53521 ctaacttaac ggaggaacta cgttacgaag ccaagcttga aaatgccaag aaacctgatg
    53581 cacttcgtcg tgtcatcatt gagaaattgg ttgagcttta tgaaaaggat ggtagctacg
    53641 atgaaagcat ccacttccaa gataacttga cagttatgct ctttgttggt gtgaatggtg
    53701 ttgggaaaac aacttctatt ggaaaactag cccaccgcta caaacgaact ggtaagaagg
    53761 tcatgctggt tgcagcagat accttccgtg cgggtgcagt agctcagcta gctgaatggg
    53821 gccgacgagt agatgttcca gtagtaactg gacctgaaaa agctgatcca gccagcgtgg
    53881 tctttgatgg tatggaacgt gccgtggctg aaggtatcga tattctcatg attgatactg
    53941 ctggtcgtct gcaaaataag gataacctta tggctgagtt ggaaaagatt ggtcgtatta
    54001 tcaaacgtgt tgtgccagaa gcaccacatg aaaccttctt ggcacttgat gcatcaacag
    54061 gtcaaaatgc cctagtacag gccaaagaat tttcgaaaat cacaccttta acgggaattg
    54121 ttttgactaa gattgatgga actgctcgag gaggtgtggt tctagccatt cgtgaagaac
    54181 tcaatattcc tgtaaaattg attggttttg gtgaaaaaat cgatgatatt ggagagttta
    54241 actcagaaaa ctttatgaaa ggtctcttgg aaggcttaat ctaatcagaa gcaaaaatcc
    54301 tgcaaggtac aaacttgcag gattttttta ttcgaaacga ccatcttgac gataggcgat
    54361 atctggttgc caagtccatt tggcatcgaa tttttcaagt aggtcaaagc tggcttgagg
    54421 tcccatgctt ccagctttat agtcatgaag tggggcacca ttttcggccc agagctcttc
    54481 aatacggtca atcaacttcc atgacgcacc aacctcatcc cagtggctaa agttagttga
    54541 gttgttattt aggacatcat aaatcaattt ctcgtatggt tctggagaag caccagttgc
    54601 agtcgcgtct gtacgataat caagtgagtt aggagccaag ttaaattctt ctcctacttg
    54661 cttcccattt aggctaagag agaagccttc tgttggttga atatagatgg tcaaaatatt
    54721 tggagcaagt ggttctccaa agatagaatc catttgttta aagacgatgt tgacatgagt
    54781 tcctttttca gtcagtcgtt tacctgtacg gaaaaagaaa ggaacaccac ggaatcgatc
    54841 gctgtctaca aagaaggcac cagatgtaaa ggtttcagtt gttgattctg gattcacatt
    54901 tggttcgcta cgataagaga tgtatttcat gccatcaatc ttaccagagc ggtattgtcc
    54961 acggataaag tgttctttga gttcttcatc agttggatga tagaggtttt taaagacctt
    55021 aatcttttca gcacgaatct cgtcttttgt gaagcttgct ggtttgtcca tggcgaggag
    55081 cgaaagaagt tgtagagtgt ggttttggac catgtcacgg agggcaccgg attggtcata
    55141 gtagccacca cgttcttcta cacccaagcg ctccgcaaag gtaatttgaa cattgtcgat
    55201 aaaatccttg ttccaaacgt tttcaaaaat caagtttgca aagcgaactg caaagatgct
    55261 ttggatcatt tccttgccaa gataatggtc gatacggaaa atttgttctt cgtcaaatgt
    55321 tgctaggagt tcgtcattca acttgcttgc agttgcgtaa tctgtaccaa atggtttttc
    55381 aacgatcaag cgctcaaaac ctttgccatc gacaatgttt tcagatttga ggtgtttggc
    55441 aatggttcca aagaactgag gtgccataga caagaagaag agcttattgt gttcagcttg
    55501 gtatttttca ttaagctcag cttgtaattg acgcaaagca atataatgtt ccgaatcatt
    55561 gacatcatgg ctttgatagt agaagtggct agcaaattct tgggcttgct cggtactatc
    55621 tgccaaatca aggatggact cgacaactac agattcaaaa tattccttac tccaaggtct
    55681 acgggcagtt ccaataacgg caaagtgctt ggaaagattg ccggatttat atagtctaaa
    55741 aagggaaggg tagagcttgc gtttagccag gtctccactc gcaccgaaaa ttgtaacaat
    55801 aaccttagat gacatctagc tacctaattt ctatttttat tcctagtctt gctaggtatg
    55861 aggaaacctc atttcataaa cttaattcta acataatttt ccgaaaaatc aaaaattcca
    55921 atacgaggta gaaaaactgc aaggaaatcc ttacagtttg agtttagacg tttaagacct
    55981 tatctaagaa ctctttcaga cgagggtgtt gtgggttatc aaagatttgg tcaggtgttc
    56041 cgtcttcaag gaactcgcca tctgcagtaa agataacgcg gttggcaacc tgacgagcaa
    56101 atcccatctc atgggttacg ataatcatgg tcatgccttg ctcagccaat tccttcataa
    56161 cgttaagtac gtctccaacc atctcagggt caagggcaga agttggttca tcgaagagca
    56221 tgatgtctgg attcattgct aggccacgag cgatggccac acgttgtttt tgaccacctg
    56281 ataggctatc tggattggca ttagctttat ctgctagtcc aaccttttca agcaactcca
    56341 ttcccaattc ctcagcttct tccttagtca tcaacttgtg ctcaatagga gcaaaggtga
    56401 tgttgtccaa tacagacata tgagggaaga ggttgaagtg ttggaatacc atgccgatat
    56461 tttcacggac gtggtcaaca ttggttgttt tttcagttaa atcatagccg ttcacagtga
    56521 tgtgaccgct agtgacttct tctaaaagat tgaggctacg gaggaaagtt gacttaccag
    56581 aacctgaagg accgatgata caaacaacat ctccttcata gaacttagtc gtaattcctt
    56641 ttaggacttc attttttcca tagtgcttgt gtaaatcatt tacatcaatt tttaattttg
    56701 ccattaacga atcctctttt ctaagcgttt cgctagtcta gtcaaaagtg tgataattac
    56761 aagatagaag atagcaagga ttgcatacat cttgaaactt tggtagttac gagcaatgat
    56821 aatcttacca gtttggaaga gttcaaccaa accgatagca gatacgatag ttgtatcttt
    56881 aagagcgata acgaattggt tgacaaagtt tggcaacatc aatttagttg cttgtggcaa
    56941 gataatctta cgcatggttt ttccataaga gatacccaag cttcggctgg cttccatttg
    57001 gccaactgga acggcctgaa taccaccacg aacgatttca gcgatataag cagccgcatt
    57061 gagtgagagg gcaattgttc cagctacaaa gtcgttaatt gggctttgtt ggcctgtgat
    57121 agactcgatg aagtttggaa ttccccagaa gatgaaggct gcaagaatca tcaatggaat
    57181 accacgaata acgtcaacga aaatctcaga gatgacgcga agagatttgt atgggctaac
    57241 gctaaacata ccgaagataa ttccgatgac aatggcaata gcaaatgaga taagagctag
    57301 agcaagagtg ataccaagac cgctaaggag ttgtttgtaa ttgttttgaa gcaagcccca
    57361 gagcgttgtt tcgtcaacag tacttgttga agcagttgaa gattcgctag ctaggtattt
    57421 gtcaagaatc ttttggaatt caccgtttgc tttaaggttt gcaagtccgt tgttgaacat
    57481 ttcaatcagt tctggatttg ctcctttttt aacggcaaag gctgtttcac cgattggagt
    57541 tccagagatt ggagttttca atttttgacc ttggctgata gaatatttga gaacaggttc
    57601 atcatccata acggcatcaa tggcaccagt atttaaactg tcatacattg aagaaccatc
    57661 agcaaaggtt ttgattttgt agccgtattt gctttgattt tctgttagga aggtttgaga
    57721 agcagttccg tttttaacac cgactgtctt tccttttaga tcttcataag aagcaatatt
    57781 gcttgattct ttgacaccaa gaatggtatt agcagtgtag tatgattctg agaagtcaaa
    57841 agttgcctta cgagcatctg tgacagacat accagcgatg ataccatcgg cttgaccagc
    57901 ttggacagca ctgatagcag catcaaaacc agggttggtg atttcaattt caaaaccttg
    57961 gtctttagcg attgccttaa tcaattccat atcaatacca gtgtattggt tgcttgaatt
    58021 ttggaaaaca aaaggtgcaa aagaagaatc gctggcaatg atatatttag ccttaacagg
    58081 aatggctttt aatcctgcga gagtagttgt agttggcact gctgaagatg atgaagcagt
    58141 ccatttcttg ataattttat caagactacc atcttttttc atttcagaca aggcttggtt
    58201 aaattcagta accaggtgct cgtatttact tccttttttc acaccgaaag caaaacttcc
    58261 tacagcttca ccatccattt caatatggag gtcttgacct tggttaatgg catattcgat
    58321 aacaggtttg tcatccatca tggcatcgat ggcaccagca ctcaagctgt tgttcattaa
    58381 atcaccagtg tcaaatgttt taatagtaaa gccgtattta tctttgattg tttcaaggaa
    58441 acgttgagcg gcagttccgt ttttaacacc aacggttttg ccagttaatt ggtcgtactt
    58501 gctaattttg tgtgactttg tagtagcaat gacaactttt gtatcatagt aagtatcaga
    58561 catggtgaag actttttcac gttctttagt ctttgtcatc cctgccatga tagcgtcggc
    58621 ttgcccagct tgaaccgcat tgactgctgc gtcaaatcca ggataggaca tctgaatgtt
    58681 ccagccttta atctcagcga ctttgttaat aatgtcaaca tcaattcctt tataagtttg
    58741 atctgaatct ttaaactcaa aaggtgcata ggcggtatca gaaacaatct taatcgtttc
    58801 tgctttggca atacctaatg agaaaattgg gaataaaatt agcaaaaatg ctagaaattt
    58861 tttcttcatt tttagtctcc ttttccgaat attctctcat tatatcagaa aaagtaaaaa
    58921 aaggcaaatt tttatatttt tcgtgtcaga aaatataaca tcgatttttt cctttccttg
    58981 aattgctatt aaaaagtgct ataataatag tatatataga agaaaagagg acggggatat
    59041 gaagaacaaa agaatattta aagacttcca agcttcaaaa atgagtttaa acatttacac
    59101 aagccccttg ttagcctttg tttttgtctt cataggagag tttgtggctt ttactttgta
    59161 tggtattggc ttgttagctc tcatcggact tgctagaaat tttggagagg ctggtcaaaa
    59221 tcttgcaagc tacttgcaga ccttgcatca gagcttgacg gataaaacaa gtgactttcg
    59281 tttaatttta ggattactgg cctttggttt tattcttaac actgtgttca gatggacaag
    59341 aaaagttgag aaaagaccta ttcgaacctt gggattttat agagagaatt tcctcagcaa
    59401 tcttctgaaa ggatttagtc taggtctggc actttttctt ctgaccttgt taggtttggt
    59461 ggtcttaggt caatatcgtt tggaatccat tcacttgaat ccttattctc ttgcctttgt
    59521 cgtctttact atcccatttt ggattttaca ggggacagca gaagaagtgg tggcccgtgc
    59581 ttggctactt cctcaattgg cctcaagaac caatctaaaa ctagctattc ttatatctag
    59641 cctgttcttt accctgcttc atatgggcaa ttctggcctc acccctctat ctctagtaaa
    59701 tctcttttta ttcggagttg ccatggctct ttaccttctc aaaactgata cagtttgggg
    59761 tgttgcaggt attcatggtg cttggaattt tgctcagggt aatctctttg ggattttagt
    59821 tagtggtcaa ccgtcaggaa cgtctctgat gaccttttta ccacaaggca atcaagattg
    59881 gctatcaggt ggttcttttg gcatagaagg ttccattatg acaagtctgg tattactact
    59941 gctgattgtc tatcttgcca ataaattaaa gaaagaaaat gaaaggatgt gacttcggtc
    60001 cgtccttttc ttcgtgaaaa tactataagt atgctaaaat aggaatagca catggagaga
    60061 ggattcttat gatcaatcac attacagata atcaatttaa actagtatca aaatatcaac
    60121 catcaggaga tcaaccccaa gctatcgagc agttggtgga taacattgag gggggagaaa
    60181 aagctcagat tctgatgggg gcgactggaa cagggaagac ctatactatg agtcaggtca
    60241 tttctaaagt caataaacca actctggtta ttgcccacaa taaaactctg gctggtcagc
    60301 tctatgggga gtttaaggaa tttttccctg aaaatgcagt tgagtatttc gtatcctact
    60361 atgattatta ccagccagag gcctatgtcc cttctagcga tacctatatt gagaaggata
    60421 gttctgtcaa tgacgagatt gacaagcttc gccactcagc tacctcagcc cttttggagc
    60481 gtaatgatgt tattgtcgtg gcctcagtct cttgtatcta tggtttgggt tcgcccaagg
    60541 aatacgctga tagtgtcgtt agtctccgtc ctggtctaga gatttctcgt gataaactct
    60601 tgaatgactt ggtcgatatt cagtttgaac gtaatgatat tgatttccaa cgcggaagat
    60661 ttcgcgttcg tggggatgtg gtagagattt tcccagcttc ccgagatgaa catgcctttc
    60721 gagtagaatt ttttggagac gaaattgacc gtatccgtga ggttgaggct ctgacaggtc
    60781 aggtattggg agaggtggat catttggcga ttttcccagc tactcacttt gtgaccaatg
    60841 acgaccatat ggaagttgcc gttgccaaga ttcaagcaga attagaagag cagttagctg
    60901 tctttgagaa ggaaggtaaa ttgcttgaag cccagcgctt gaaacaacgg acagagtacg
    60961 atatcgaaat gctgcgcgag atgggctata caaatggggt tgaaaattat tctcgccaca
    61021 tggatggacg gagcgaagga gagcctcctt atacgcttct cgactttttc ccagatgatt
    61081 ttttgattat gattgacgag agtcatatga ctatgggaca aataaaaggc atgtacaatg
    61141 gagaccgttc gcgtaaggaa atgctagtaa attatggttt ccgtttaccg tctgccttgg
    61201 acaatcgtcc tctccgtcgt gaggagtttg aaagccatgt gcatcagatt gtttacgtat
    61261 cagcgacacc tggtgactat gaaaatgaac agactgagac ggtgattgag caaatcattc
    61321 gaccgacagg gcttttggat cctgaggtgg aagtccgtcc gactatggga cagattgatg
    61381 atctcttagg tgaaatcaat gcccgtgttg aaaagaatga acgaaccttt atcaccacct
    61441 tgaccaagaa aatggcagag gacttgaccg actatttcaa ggaaatgggc atcaaggtca
    61501 agtacatgca ctcggatatc aagaccttgg aacggacgga gattatccgt gatctccgct
    61561 tgggtgtctt tgatgtcttg gttggaatca atctccttcg tgaagggatt gacgttcctg
    61621 aggttagctt ggttgccatt ctcgatgctg acaaggaagg tttccttcgt aacgagcgtg
    61681 gactcatcca gaccattggg cgtgccgccc gtaacagtga aggtcatgtc atcatgtatg
    61741 cagatacggt tacccagtct atgcaacgtg ctatcgatga aactgcccgc cgtcggaaaa
    61801 ttcagatggc ctataatgaa gagcatggta tcgtaccaca gacaatcaag aaagaaatcc
    61861 gtgacctgat tgccgtgacc aaggcagttg ctaaggaaga ggacaaggaa gtcgacatca
    61921 atagcctcaa caaacaagag cgcaaagaac tcgtcaagaa actagaaaaa caaatgcaag
    61981 aagccgtcga agtgcttgac tttgaactgg cggctcagat ccgtgatatg atgttggaag
    62041 tcaaggcctt ggattagggg aattagtatg atttatttaa gaaagttaaa gaaagaagat
    62101 ttgatgtctt tatgggaaat ggcttattca cagcttaatc cagtttggaa acagtatgat
    62161 gctccctatt atgatgatta tcagtatttt tcaaatttta aagaattcga actacaaaaa
    62221 tcagaatcca ttttaagcaa ctcaaatcgc cttggtattt ttgttgatga taaactagtt
    62281 gggactgttt cgcgttattg ggtatgtaaa gaaacaagat ggatggaatt gggaattggt
    62341 atttatgata aaaaattctg gaacactggt attgggaaag ttgctatgtt gcagtggata
    62401 gataggacgt ttcaggatta cttggagttg gagcatctgg ttttgacaac ttggtcagga
    62461 aatcttggta tgatgaaact tgctgaaaaa ttaagaatga aaaaagaagc tcatattcca
    62521 aaagttcgtt attatcaagg taaatatttt gatagtatta aatatggtat tttgagagaa
    62581 gactgggaga aaataaatga cggttattat caaatcaatg gaaactcctg aagagataga
    62641 aggcaaatcc ctcgttcact ggcaaacgtg gagagagtct tatgatgacc ttttgcctgc
    62701 ggaatttcag gatacaatga cattagaaag atgtcgattc tttagtcaaa agtatccaga
    62761 aaatacattg attgcgatgg atggcgtgaa ggtggttggt tttatcagtt atggcaattt
    62821 tcgtgatgag actattcaag ctggtgaaat tattgcttta tatgttttaa aagactatta
    62881 tggaaaaggt atcgcacaaa agttaatgaa agcagctttg actgctctta atcatttttc
    62941 tgaaattttc ttatgggtat tgaaagataa caagcgcgcc attgctttct atcaaaaaat
    63001 gggttttact tttgatggac aagaaaaaat acttgaactt ggaaagccta taaaggaaaa
    63061 acgaatggtg ttctattcta aataatttta aaaaagtaaa agataatatc tctggtagta
    63121 agtctgaaaa tttaataaat tagaaagcga gtaaatttat gtcccgttcc caattaacaa
    63181 ttttaacaaa tatctgtctg attgaagacc tcgaaactca gcgcgtggtg atgcagtatc
    63241 gcgcccctga aaacaatcgc tggtctggtt atgcctttcc tggaggtcat gtagaaaatg
    63301 atgaggcttt tgcggagtct gtcattcgtg aaatctacga agaaacaggg ttgactatcc
    63361 aaaatcctca acttgtcggc attaaaaatt ggccactaga tacaggtggg cgctatattg
    63421 tcatttgtta taaggcgact gagttctctg gtacccttca atcttcagaa gagggagaag
    63481 tttcttgggt gcaaaaagac cagattccaa acttaaatct ggcctatgat atgctaccat
    63541 tgatggaaat gatggaagct cccgacaagt cagagttttt ctatcctcgc cgtacagaag
    63601 acgattggga aaagaaaatc ttctagtctt ttactaaata acctagctga tccaaggcct
    63661 cctcgatata gtggaggtct tgttgtgttt cggcttcgac taggtggtaa tggatgccat
    63721 ctgtcaattc agatagaggt ctaaagtcag aatgctcgac ttgttctaga aaatgttgca
    63781 catctctgcg acaagacagt ttaagcaagg tttcaatttc tccataaacg ggatggtcaa
    63841 tcaaggtatt ctggacatgc ccaccattat cgacaatagc aaggagttcc tgaccgattt
    63901 cttcaacttc atgtttcact ttgaaaagtt tgtgaacata aggattggta tcaatttgct
    63961 tatagatgta gccacgattg gtggatagga taggagcgcc atcggctctc aaaattgcaa
    64021 tgtcctgcac aatgacctga cgtgtgacat gaaaatgttc cgccaaactt tggccattaa
    64081 gggctttagg agcttctttc aagagttgga gcagggcttg tttgcgatct tttgtcatag
    64141 cttttccttt taacggcgtt ttcgaagcac tttatagaca gctagtgcta atgtatagtc
    64201 taccatacta tggataattg tgccaaatcc aactagtaca aatagaacat agaacatatt
    64261 ttctacattg gtacccgaag ttgcgtaaaa aaggacacag gctaatactt cagcaagggc
    64321 atgaacaaca gccaaaacaa aattgaaaac ccaggaagat tttggtttat ctagggtatc
    64381 ggggaatttt tgtaggtaaa gagctcctaa agcaccaaaa gatatatggg aaaaagcccg
    64441 aaaaacgata accatgggat agccagccat caaaaatcca aaactagagg ctaggatgac
    64501 aaaaactgcc atcaagggcg acaagaacat ggctataaaa atagcgatgt ggctccccaa
    64561 agtataggaa gcaggtggaa tgacaatctt gaaaggcata acaattggaa tcaaaatcgc
    64621 aatagccgtt aaaagggctg tcattgtcat aaattgtgtc tttttccgtg tattcacaag
    64681 aatctccttt ttaactgcat atacactagt atggtacaat aaaccagaca ataaagcaag
    64741 aatttacttg ggtttataga tcatttttta gttaaaagtt atagtagatg gaaactagaa
    64801 tagtccacct ctacttctaa aacattgtta gaaatcgatt tgactgtcct gatcgatttg
    64861 tcctgttctt atttcgtttt actatagtaa agatttcatt aaaaagaaac tgtatagagc
    64921 aaaatctcca ccttcaggtt tgaaagcgga gattgttttt attttttcaa ggtttgtagt
    64981 cgtggaacaa tggctagggt tagaattgca gaaatgacca attcagcaat tgaatttgtt
    65041 gagataacgg ttgccagaag aagttggata tttccattat aaacatttcc aaataggaag
    65101 aagattcctc caaggacaaa gatagtattt gtcaaggaac cgagggctcc agctaaaatc
    65161 agaccagtct tgtttttcat cagtttatag actaagtaag gagttaaacc aatcaaaata
    65221 cgtgggacga tggcaatgat agctgagtag atgtttccgt ttggtacgaa gggagagaag
    65281 aggtagcttg tcggtagaat cgtaatcgtg ttaaccgtca agctaagtaa tcccatcaaa
    65341 aatccaagtg taaccccaac tcgtggacca taaataatgc tggcaataat gacaggaata
    65401 tgaacaatgg tcggtttgat tggaaatgga aaaaggttaa agataagtga gctcagaaag
    65461 tgtatcacga gcatggtagc aaaaaagata gcaatgggtg caatattaga gcgttttttc
    65521 atcgatagtt tcctttattc tttctaaaat aattgtgagg tcagctaaag ctcctcgtcc
    65581 gtggtctcca caagctagta gggattcctt aggagcaatc agctgatagc cgtaggtttc
    65641 taatgttttc agattattct gagttactgg atggtcatac atttttgtat tcatagcagg
    65701 agctattagt ttgggaatat gacttggtag ggctagagct gtactggtta ccatgttgtc
    65761 cgcaaatccg tgagctagtt ttgcaatagt gttagcagtt gcaggtacca cgataaataa
    65821 atctgctttt tttccaagtt cgatatgatt gacctgatca ggatagggtt ccttcatgac
    65881 atccaagtgg acaggattct gtgagagtac ctgtagtgtc aaaggttgga taaactctgt
    65941 agcagcctga gtcattaaga cagtgacttg atggccttgt ttttttagag aactgactaa
    66001 atctgccgac ttataagagg cgattgaacc cgttacagcc aagagaatgt ttgccatagt
    66061 tttcctttct aagaatgata ggcttgaatt ttttcaagga ggagttctgc aatttcttct
    66121 ttagtctgga ctgtttgaag ctgatttttc tcaacaaata tagctcggtg ctgatctgct
    66181 gaaatttgag tcaggtcatt cgcgatgatt aaatctgctt gattcttgat aagacttttt
    66241 cgtgcaatgt caaccagatg atcttcggta acatcaacca gcagtttgaa accaatcaga
    66301 tgaatagtgg gattccattc cttgactagg gatatgattt tgggtgtctt tttaaggaac
    66361 aaaacctgaa cctcatcagt tgaagaaatc ttggcctgat gattctgctt gcttaaaaat
    66421 tcttttagat tggagctagc ctgaacttcc tcaagccctg tcatataaac aggagtgtag
    66481 tcagaaacag ccattgagtg gatcaagacc tgataatcct gaacacgttc ttgcatttct
    66541 attagaaggt ccttggtatt ggtaatttct cgaatactta ggttaggatg aggctctggc
    66601 ttcagagctc gttttgtcgt aattaaacaa acttcatgcc ctgcagaaag caaagtctct
    66661 gtgataattt tccccaagtg acctgtagaa tggttagtga tagagcggac gctatcgata
    66721 gcttcactgg taccgcccga tgtaactaaa attttcatag cactattgta cacaaaaata
    66781 agcggtaagt aaaatgaaag tgataaattt ttggtaaaaa cgaagattta ctatagtttc
    66841 aaactataaa gccatataaa atttaagaaa ggactctaaa atccttaaaa acagagatat
    66901 ttacgaacgt ttagagagtt ttaggatgtt aaaaatcttg ttttgtgata taatgaatta
    66961 tcatataaga ggttagagga attttgaatg aaaacagata ttgaaatcgc acagagtatt
    67021 gagttgaagc caattgttga tgttgtagag aaacttggta tttcttatga cgatttggag
    67081 ttgtacggaa agtacaaggc taaactcagc tttgataaaa ttcgtgcagt tgagagcaat
    67141 ccagtcggta aattgatctt ggttactgcc atcaacccaa cacctgcagg tgaaggaaag
    67201 tcgacgctta ccattggtct tgcggatgcc ttgaacaaga ttggcaagaa aaccatgatt
    67261 gctatccgcg aaccgtctct tggtccagtc atggggatca agggtggtgc tgctggtggt
    67321 gggtatgcac aagttctgcc aatggaagac atcaacctcc actttactgg agatatgcat
    67381 gctattacaa ctgccaacaa tgccctttct gccttgattg acaaccactt gcaccaaggg
    67441 aatgagctgg aaattgatca acgtcgtatc ctctggaaac gcgttgtgga cttgaacgac
    67501 cgtgcgctcc gccatgtgac tgttggtctt ggtggtcctc taaacggtat tccacgtgag
    67561 gatggttttg atattacagt tgcttcagaa atcatggcaa ttctttgctt ggcaacggac
    67621 atcgaggact tgaaacgtcg tttggcgaat atcgttattg gttatcgcta tgaccgtacg
    67681 cctgtttctg taggtgattt gcaggttgag ggtgccttgg ctttgatttt gaaggatgct
    67741 attaagccaa acttggttca gacaatttac ggtacacctg cctttgtaca cggtggtcca
    67801 tttgccaata tcgctcatgg ctgtaactct gttttggcga cgacaacagc ccttcacttg
    67861 gctgattaca ctgttactga agctggtttt ggtgcggacc ttggtgctga gaaattcctt
    67921 gatatcaaga caccaaactt gccaacatct ccagatgcag ttgtcattgt cgcaaccctt
    67981 cgtgccctta agatgaatgg tggtgtggct aaagacgctc tgactgaaga aaatgtagag
    68041 gcagttcgtg caggttttgc taacttgaaa cgccacgttg aaaatatccg taagttcggt
    68101 attccagcag ttgtagctat taacgaattt gtatctgata cagaagctga aattgcagtc
    68161 ttaaaagaac tctgtgcctc aatcgatgta ccagttgaat tggctagtgt ctgggctgat
    68221 ggagcagaag gtggagtagc acttgccgaa acagttgtta agacaattgc tgaaaatcca
    68281 gctaactata aacgtttgta cgataatgcc ctttctgtcc aagaaaagat tgaaaaaatt
    68341 gtcactgaaa tctatcgtgg tagcaaagtg aactttgaga agaaagctca aacacaaatt
    68401 gctcaaatcg ttcaaaacgg ttgggacaaa ttgccaatct gtatggctaa aactcaatac
    68461 agtttctcag acaatccaaa tgcgcttgga gcaccagaaa actttgaaat taccattcgt
    68521 gaattggtac caaaattagg tgcaggcttc atcgttgcct taactggtga tgttatgacc
    68581 atgccaggtc ttccaaaacg tccagcagct ctcaacatgg atgttgaaag cgatggaact
    68641 gtactaggct tgttctagtg gattgaaatt gactttaagt gagtttggaa ataatatcca
    68701 agctcatttt ttctcagact gcaagcagtt catcaataag atttatactc ttcgaaaatc
    68761 tcttcaaact acgtcagctt caccttgccg taggtatatg atactgactc tgtcagttct
    68821 atccacaacc tcaaaacagt gttttgagca acctgcggct agcttcctag tttgctcttt
    68881 gattttcatt gagtataagt agatagaaaa gttatatact atctattgaa aatattataa
    68941 atcagataca aagacaggtg aaaccttctg tgttatacta gagatatgtt agatttgaaa
    69001 gaatacggta tcgtcatgtg gccggaggag aaagtcattt ctttccgtga gaaacttctc
    69061 gcttggtatg atgaaaacaa aagagatttg ccttggagga gaagtaaaaa tccttatcac
    69121 atctgggtat ctgaaatcat gcttcagcag accagggtgg atacagttat cccttactac
    69181 gaaagattcc tggactggtt tccaactgtc gaaagtctgg caactgcgcc tgaggagagt
    69241 ttactgaaag cttgggaggg cttgggctat tattctcgag ttcgcaatat gcaggctgca
    69301 gcccagcaga ttatgactga ctttggtggc caatttccaa atacctatga aggaatttcc
    69361 agcttgaaag ggattggacc ttacacagca ggagccattt ccagtattgc ttttaacttg
    69421 cctgagccag ctgtagatgg taatgtcatg cgggtcttgg cgcgtctgtt tgaagtcaac
    69481 cacgatattg ggattccaag taatcgaaaa atttttcagg caatgatgga gatcttgatt
    69541 aatccggatc gtccgggtga ttttaatcaa gcattgatgg acttagggtc tgatattgag
    69601 tctcctgtaa atcccagacc tgaagaaagc ccagtcaagg actttagtgc ggcatatcag
    69661 aatggaacca tggaccgtta tccaattaaa tctcctaaga aaaagccggt tcctatttat
    69721 cttaaagcct tagttgtgaa aaattctcaa ggacaatttt tacttgaaaa aaatgaaagc
    69781 gaaaagctct tggcaggttt ttggcatttc ccctttatag aagttgataa cttttcgcaa
    69841 gaagagcagt ttgacctctt tcatcaggtt gcggaagaaa gtgtgaactt tggtcccagt
    69901 ccagaagaga gtttccagca ggactatgac ctagatgttg attggcttga tgtttgtttt
    69961 gatacagtcc agcatgtttt tagtcatcga aaatggcatg tacagattgt agcaggtcag
    70021 gtgagtgact tccatgattt ttcagatagg gaagttcgtt ggctttcacc agaagaattc
    70081 aagaattacc cacttgccaa accccaacaa aaaatctggc aggcttatgc acaagccaac
    70141 ttagacagta gccaagacta gctattgtgt cttctgacta tttttttggt ataatagtag
    70201 agaaaaaggt gaacatatga aaaaaatact aattgtagat gatgagaaac caatctcgga
    70261 tattatcaag tttaatatga ccaaggaagg ttacgaagtt gtaactgctt ttaatggtcg
    70321 tgaagcgcta gagcaatttg aagcagagca accagatatt attattctgg atttgatgct
    70381 tccagaaatt gatggtttag aagttgctaa gaccattcgt aagacaagca gtgtgcccat
    70441 tcttatgctt tcagccaaag atagtgaatt tgataaggtt atcggtttgg aacttggggc
    70501 agatgactat gtaacgaaac ccttctccaa tcgtgagttg caggcgcgtg ttaaagctct
    70561 tctgcgtcgt tctcaaccta tgccagtaga tggtcaggaa gcagatagta aacctcaacc
    70621 tatccaaatt ggggatttag aaattgttcc agacgcctac gtggctaaaa aatatggcga
    70681 agaactagac ttaacccatc gtgaatttga gcttttgtat catttagcat cgcatacagg
    70741 tcaagtcatc acgcgcgaac acttgcttga gactgtctgg ggttatgact attttggtga
    70801 tgtccgtaca gttgatgtga ctgtacgacg tctgcgtgag aagattgaag atacgcccag
    70861 ccgaccagag tatatcttga cgcgccgtgg tgtagggtat tacatgagaa ataatgcttg
    70921 atttactgaa acaaaccatt tttaccagag attttatctt tatcctgatt ttgttaggtt
    70981 tcatccttgt tgtgaccctc ttattactgg aaaatagacg tgataatatt cagttgaagc
    71041 aaatcaatca aaaggttaaa gatttgattg caggagatta ttccaaggtt cttgatatgc
    71101 aaggtgggtc tgaaatcacc aatattacca ataatttgaa tgacttgtcg gaggttattc
    71161 gtctcactca ggaaaatcta gaacaagaga gtaagaggct aaatagtatt ctgttttata
    71221 tgacagatgg ggttcttgcg accaaccgtc ggggtcagat tatcatgatt aacgatacag
    71281 ccaagaagca actggggttg gttaaggaag atgttctgaa tagaagcatt ttggaattgc
    71341 tcaagataga agaaaactat gaattgcgtg atttgattac ccaaagtcca gaattgttgc
    71401 tagattccca agatatcaat ggtgaatatt tgaaccttcg agttcgcttt gccttgatac
    71461 gtcgagagtc tggctttatt tcaggtttgg tggctgtttt gcatgatacg acggagcagg
    71521 agaaggaaga acgcgaacga agactctttg tttccaatgt tagccatgag ttacggactc
    71581 ctctgactag cgtaaaatcc tatcttgaag ccttggatga gggggctttg tgtgaaactg
    71641 tagcaccaga ctttatcaag gtttctcttg atgagaccaa ccgtatgatg cgcatggtga
    71701 cggatctcct ccatctttca cgtattgata atgctaccag tcacctagat gtggaactga
    71761 ttaacttcac tgcttttatt acctttatcc tcaatcgttt tgacaagatg aaaggacagg
    71821 aaaaggagaa aaaatatgag ttggtgagag attatcccat caattctatc tggatggaaa
    71881 ttgatacaga taagatgacg caggttgtcg acaatatttt aaataatgct attaagtatt
    71941 cgccagatgg gggtaaaatc actgtcagaa tgaagacaac tgaagaccag atgattttat
    72001 ccatttctga ccacggtttg gggattccta agcaggattt accacgtatc tttgaccgtt
    72061 tctatcgtgt ggatcgtgct agaagtcgtg cacaaggtgg tacaggtcta ggactgtcta
    72121 tcgctaaaga aattattaaa caacataagg gctttatttg ggccaagagt gaatacggca
    72181 agggttcaac ctttaccatt gtgctccctt atgataagga tgcagtgaaa gaagaagtat
    72241 gggaggatga agtagaagac tagaatgagt gaaataggct ttaaatacag tattttagcg
    72301 tcgggttcca gtggaaattc tttttatctg gaaacctcaa aaaagaagct tttagtggat
    72361 gcaggcttgt ctggcaagaa aattaccagt ctgctagctg aaattaaccg caagccagaa
    72421 gacctggatg ccatcttgat tacccatgag cattcagatc atatccatgg agtaggcgtt
    72481 ttggctcgca agtatggtat ggatctttat gccaatgaaa agacctggca agctatggaa
    72541 aatagtaaat atcttggcaa ggtggattct tcgcaaaagc atatttttga aatgggtaaa
    72601 accaaaactt ttggagatat cgacatcgag agttttggtg taagccatga tgcagtcgca
    72661 ccgcagttct atcgctttat gaaggatgac aagagttttg tccttttgac agatacaggt
    72721 tatgtcagtg accgtatggc gggcattgtc gaaaatgcgg atggctatct tatcgaggcc
    72781 aaccatgatg tagagatttt gcgatcaggt tcttacgctt ggcgactcaa acaacgaatc
    72841 ctatctgacc ttggtcacct ttctaacgag gacggtgctg aagctatgat tcggacgcta
    72901 ggaaatcgca ctaagaagat ttaccttggg catttatcta aggaaaacaa tatcaaggaa
    72961 ctggctcata tgaccatggt caatcagctg gctcaagctg atctgggagt cggagtagac
    73021 tttaaggttt atgatacctc accagatacc gcaacaccat tgacagagat atagaaagaa
    73081 cgctgagaag gtgttctttt tatattgact gaacacctaa aaagtaatac aatggtgtta
    73141 ccattaaaaa agggagcaca aaagatgact actattacat taaaagtttc tgaagctgat
    73201 aaaacattta tgaaagcaat ggctaagttt gaaggagttt ccctttcgga acttattcgc
    73261 accaaaactc ttgaagccct agaagatgaa tacgatgctc gtgtggcaga tttagcctat
    73321 caagagtatt tagaagactt ggaaaaagga gttgaaccca ttacttggga agaaatgatg
    73381 catgatttag gcttgaagga tgaataattt gtataaatta gttccaacaa gacgttttat
    73441 caagcaattg aaaaaattgg accgttatac gcagaagcta attacaaact atttacaaac
    73501 caatgttttg gaagacccaa gacgacacgg aaaggctttg gttggtaatc gcgttggtca
    73561 atggcgctat agaattggta attatcgagt tatcgtacaa attgtagatg atgaattagt
    73621 cgttgctact ctagaagttg gtcatcggag agatatttat tgaattactt ttttcaagta
    73681 aattttcatt ctttaaaata tgatataata gggcttacaa tataagagag gttgctgatg
    73741 acaatagata ttagtgaaga aagtttggct aaagaatcgg ctgacttatt aaaaattctt
    73801 ttaaaagatc gaacgacaaa gaaatcaatt gtttgggcta cgcattctta tgaattgtta
    73861 ggaaagggat ttgctccaag tgatcgcatc aatccaagta aggttactgg aaactttgcc
    73921 aacttgattc agcccagatc tgaaaaatcc aaatatgaac aaaaagatcg gacaaaaata
    73981 agggcagaag tgtttacacc aacgtggttg gtcgcaaagc aaaatggata tgtagaatcg
    74041 aaattaggct cgttaagtct tgaggagtat gtggacttac gatggttaga ggtaacttgt
    74101 ggtgaagcac cttatatggt aacgagatat gataccgtaa ctggtgagga aattccatta
    74161 tctgagcgag ttggttttgt tgatagaaaa ctgcaacgga ttagtcgtga ggtttcagat
    74221 gaagtcacat tttataaact tgtaaaagat gcttatcatg cttcgtatgg ttatgagtat
    74281 caaggagatt ctctcctttt ggcgcgtgag aatcttttgg caacttttga ggactattat
    74341 ctagctaaga ctggaaatca accaacatta gagcaaaaga aagaaattgc gactattatc
    74401 tcttacaatg tctttcagat ggatggattg aaaaaaagta gtccttattc agctaaacaa
    74461 aagcaatctc aacaattgag tttgtttgcg gatgagctag aagtccaaga agtagaagaa
    74521 tctaaaaccc atatcaaaga ctggaaaaag aatagaatga taggttttga gcgcctatct
    74581 agcgaggaaa gtgaaatgaa atttgatgtc gtgataggaa atcctccgta tcaggaaaca
    74641 ggagaagcca gagatgagcc gatatatcac tattttattg atgaagctta taaaatcgca
    74701 gataaatcta tactaatcac cccagcaagg tttttattta aagctggtca aactcctaaa
    74761 aattggatgg aaaagatgct tgaagacaag catttaaaag ttcaattcta tgaacttaaa
    74821 agcggtaaag tatttacagg aacggatatt aagggtggag tagcaataac ttatcgtgat
    74881 gttgataaag atttgggacc aatcggagta tttactattt ttgaaacttt gaatggtatt
    74941 gtaaaaaaaa tcgaaaaaca tccagaattt gaaacttttt ctgatttagt ttatcctcaa
    75001 ggtatttata gattttcaaa taaacttttt tctgattatc caaatgctga aaagctgcaa
    75061 ggaaaaggga caaaaaataa aattgtttcg aaatcactaa ctcagttaga ttttgttttc
    75121 aaaaacaacg aagaaaaaga ccatgttgct ctacttggaa gaattggctc cgaacgtgtt
    75181 tatcgatata ttaataaaaa atatttagat ttaccggaaa cattcgaaaa ttataatgtt
    75241 tttgtaccag aagctaatgg aagtggtgcc ttaggtgaag tcttatcaac acccctaatc
    75301 ggggaacccc taatcgggca tacagatact tttttatcta ttggtaattt taaaacaaaa
    75361 tttgaagccg atgcttgtat taaatttatt aaaactaaat tcgctagagt attattaggt
    75421 gttttgaaag ttactcagca taattcacgc aaaacttggt attacgtccc cctccaagac
    75481 tttacggtca attcggacat tgattggaca caatcagtgg ctgatattga cctccagctt
    75541 gatcaaaaat atgacctttc ccctgaagaa attgccttta ttgagaatca tgtaagggag
    75601 atggattaga aaagtatttt tatttgacaa atagtgctca atgatctaaa atgactatat
    75661 aggattaggt caggaagcat acgatgccct gacccttttt gtacttatga gatgagaaag
    75721 tcatttgtta gataaattga cttcgttagc aaacgttcaa aaaaggaaaa cttatgccag
    75781 tagaaattaa aaccactaaa gagattcatc ctaaaatcta tgcctatacc acaccgacag
    75841 taaccagtaa tgaaggctgg attaagattg ggtatacaga acgtgatgtc acacaacgta
    75901 tcaaggagca aacgcataca gctcatatag ctacagatgt cttatggact ggtgatgcag
    75961 cttatacaga agagcctgat aaggggaaaa ctttcaagga ccatgatttc caccatttcc
    76021 tttctttcca tgatgtagaa cgtcgtccca agacggaatg gttctatttt aatggaactc
    76081 ctgaaaaatc aaaaaatctt tttgataagt ttgttcagca tgatttgtct ggttatcagc
    76141 ctggaaaagg acaggactat actctgcgac aagagcaaga agaagcagtt gctaagacat
    76201 tagcttattt ccaagaacat gctggaggca agtttctctg gaatgccaag ccacgctttg
    76261 gtaaaacctt gtctacctat gacctagctc gacggatgga agctgtcaat gtcctaattg
    76321 taacaaaccg ccctgccatt gctaactcat ggtatgatga ttttgaaaca ttcatagcag
    76381 gtcaaacgac ttacaagttt gtttctgaat cagatagcct taagagtcgt ccaatcttgt
    76441 cacgacaaga atttcttggt attttagctg acgatgtaag acaacttgct tttatcagtc
    76501 tccaagactt gaaaggatct gtttatttag gtggagagca cgataaactc aaatgggtaa
    76561 ctgatctgca ttgggacttg ttggttattg acgaggctca tgaaggagtt gataccttca
    76621 agactgacca agcctttaat aagattcgac ggaattttac tctgcatttg tcaggtacat
    76681 catttaaagc attggctaaa ggagatttta cagaggaaca aatctacaac tggtcttatg
    76741 ctgatgagca ggctgctaag tattcgtggt ctcttgagca agaagaggaa aatccttatg
    76801 aaagcttgcc tcagttgaat ctctttacct atcaaatgtc tcagatgatt ggcgaaaagt
    76861 tagaaaaagg cgctcagatc gatggtgaaa atattgacta tgtttttgac ttaagtgaat
    76921 ttttcgctac agatgataaa gggaaattta ttcatgagca tgatgtcaga aattggttag
    76981 atactctatc aagcaatgaa aaatatccat tttcaaccaa agaactccgt aatgaactca
    77041 agcatacttt ttggctttta gaacgtgtcg cttcggccaa agcattaaaa gccctactag
    77101 aagaacaccc aatctatgaa aactatgaga tcgttctagc tgctggtgac ggacgtatgt
    77161 ccgaagaaga cgataaagtc aaactcaaat ccttggactt ggttagaaaa gcgatagcag
    77221 agaatgacaa aaccattacc ctatccgttg gtcagctgac gacaggtgtc actatccctg
    77281 aatggacagg tgtattgatg ttatcaaatt tgaaatcacc agctctttat atgcaggccg
    77341 ccttccgtgc tcaaaatcct tactcatgga gcgataacaa aggaaatcac tttcgcaaag
    77401 aaagagccta tgtatttgac tttgcgccgg aaagaacctt gattctcttt gatgagtttg
    77461 ccaacaactt atcgcttgta actgcagctg gtagaggaac ttcagctaca cgcgaagaaa
    77521 atattagaga attattaaac ttctttccaa ttattgccga agaccgtgct ggtaagatgg
    77581 ttgaaattga tgcaaaggca gttctaacca ctcctcgcca gataaaagct agagaagttc
    77641 ttaaacgagg ttttatgtcc aatctcttat ttgataatat tagtggtatt ttccaagcaa
    77701 gtcaaacagt tttagatatt ttaaatgagc tgccagttga aaaggaaggg aaggtacaag
    77761 atagttctga tttattagat ttttcagatg ttacagtcga tgatgaggga aatgcagtag
    77821 tagaccatga aattgtagtt aatcagcaaa tgcgactttt tggtgaaaaa gtttatggac
    77881 ttggtgaatc tgttgctgag ttagtcacaa aagatgagga acgaactcaa aaacagctgg
    77941 tcaatgactt gagtaagacc gtttcttcag tgattgtaga ggaattgaaa gcagattatt
    78001 ctctaaaaac aagggaaact gagcaaatta agaaacaaat tacagcaaca cttgagaatg
    78061 aaattcgaaa aaatgatatc gaaagaaaaa tttctgaagc tcatatcaag caagagttgc
    78121 aacagcagct caaagaagca aatgataaag cgcaaaaaga taagattcaa gaagatttag
    78181 aaaaacgttt agaagaaaat aaactcattc ataaagaaaa actagaacaa acactcaaaa
    78241 aagaagtgga aaaaatgcct gagaaattta tcgaacaggt tgagataaaa cgtgtggaac
    78301 agttgaaaca atcagctcaa gatgaaattc gtgaccattt acgagggttt gcaagaacaa
    78361 ttccaagttt tattatggct tacggtgatc aaactctaac acttgataat tttgatgcct
    78421 ttgttcctga acatgttttt tatgaagtaa cagggattac gattgatcag tttagatatt
    78481 tgcgagatgg tgggcaggat tttgcagggc atctctttga taaagcaaca tttgacgaag
    78541 ctattcaaga atttcttcgc aagaaaaagg agttggcgga ttattttaaa gatcaaaaag
    78601 aagacatttt tgactatatt ccaccgcaga agaccaacca aattttcact cctaaacgag
    78661 tggtgaaaag gatggtagat gatttggaaa aggaaaatcc agggattttt gatgatccat
    78721 ctaagacttt tattgattta tatatgaagt caggcctcta tattgcagaa cttgtgaagc
    78781 ggttatataa tagcaatggc ttgaaagagg cctttccaaa tcctgaagaa cgcttaaaac
    78841 atattttgga aaagcaagtt tatggatttg ctccgtctga gattatctat aacatttcca
    78901 ctaattttat atttggtaat ctttctaaag atatcagtag gaagaatttt gttttagcag
    78961 ataccattcc agcggctaaa gaagggagca ttcaaaagtt ggttgattcc tattttgaaa
    79021 ataattaaaa agaaggccga gtcaaaattc tttgaaatca gaaaaaacgc ataatattga
    79081 gtgcttttgt actgccccca aaaagttaga cagaaaaaat ctaacttttg gggggcagtt
    79141 cagacaatcc ttggtattat gcgttttatt gtgggaagat gtataatgga ttgaaataag
    79201 atatgaacaa atcgattagg aaaggaaaat tgatttatag aaatgtttta gtagtcgatg
    79261 cgtactgtta tagattcaac gaactataaa atctgaagaa agcaatttta accagatctt
    79321 agaagcagtt gtgtactact ctaacttcaa tagactatat catatagata aaaaacaact
    79381 ccctgatgat tcaaggagtt gtctatagtt aaattagttt ttagaagctt cttggaattc
    79441 tggatttttc catgcttcgt caatgatagc ttgcaattct ttagcagatg cttgcatttt
    79501 ttgagtttct gcatcgttca atggaatgtt tactggacga acgataccat gtgcaccaac
    79561 aacagctggt tgaccgataa agacattctc aactccgtat tgaccttctt ggaatactga
    79621 aagtggaagt actgcgtttt catcgtcaag gattgcttta gtgatacgag caagggctac
    79681 tgcgataccg tagtatgttg cacctttttt gttgatgatt gtgtaggctg catcacgaac
    79741 accttcgaac aattcaatca attcagcttc ttgaacattt tgagtgtctt taaggaattc
    79801 ttcaaggttt acaccagcga tgttagcgtg tgaccaaaca gcgaactcag agtcaccgtg
    79861 ttcacccatg atgtaggcgt gcactgaacg agcatccaca tccaattttt cagcaagtgc
    79921 ttgacggaaa cgagctgagt caagtgaagt acctgaaccg ataacgcgtt ctttagggaa
    79981 accagagaat ttccaagttg agtaagtcaa aacgtcaact gggttagcag caacaaggaa
    80041 gatacctttg aaaccagatt caacaacttg agttacgatt gatttgttga tagcaaggtt
    80101 tttacctaca aggtcaagac gagtttcacc tggtttttga ggtgcacctg cagtgatcac
    80161 aacaaggtca gcgtctgcac agtcagagta ttgagctgca tagatttttt taggtgaagt
    80221 gaaggcaagg gcgtgactaa ggtcaagcgc atcaccaaca gctttttcat gcaattgtgg
    80281 aatttcgata attccaagct cttgtgcaat tccttggtta acaagtgcaa aagcgtaaga
    80341 tgaacctaca gcaccatcac cgacaaggat aacttttttg tgttgtttag ttgaagtcat
    80401 tgttttaaac atctccttaa ttttattagg ggattttccc tagacaactt cattctatca
    80461 cttttaaaaa actttgtcac gaatatgcct tatagttctc gatgtaaacg ttttagtggt
    80521 ttagaggctg aaatagatgg gaatttatgg tataatgttg ttacttacta attgtgaaat
    80581 gaggcattta ttaatgcagg ataaaaattt agtgaatgtc aatctgacaa aggagatgaa
    80641 ggcaagtttt atcgactacg ccatgagtgt tatcgtagcg cgagctcttc ctgatgttcg
    80701 agatggctta aaacctgttc accgtcgcat tctctacgga atgaatgaat tgggtgtgac
    80761 cccagacaaa ccccataaaa aatctgctcg tattacaggg gatgtcatgg gtaaatatca
    80821 cccacacggg gattcctcta tttatgaagc catggtccgt atggctcaat ggtggagcta
    80881 ccgttacatg cttgtagatg gtcatgggaa ttttggttcc atggatggag atagtgctgc
    80941 cgctcaacgt tataccgagg cacgtatgag caagattgct ctggaaatgc ttcgtgatat
    81001 caacaaaaat acagttgatt tcgttgataa ctatgatgcc aatgaacggg aacccttggt
    81061 cttgccagcg cgttttccaa accttttggt taatggagca actggtatcg cggttgggat
    81121 ggcaaccaat attccacctc ataatctggg tgaaaccatt gatgcagtga agttggtcat
    81181 ggataatcct gaagtgacta ccaaggactt gatggaagtc ttgcctggac cagattttcc
    81241 aactggtgct cttgtcatgg ggaaatcagg tatccataag gcttatgaaa caggtaaagg
    81301 ttcgattgtc ctacgttctc gtacagagat tgaaacgact aagactggtc gtgagcgtat
    81361 cgttgtaaca gaatttcctt acatggtcaa taaaaccaag gtgcatgagc atattgttcg
    81421 cttggttcag gaaaaacgca ttgagggtat cacagcagta cgtgatgagt caaaccgtga
    81481 aggtgttcga tttgttattg aagtcaagcg cgacgcctca gccaatgtta ttctcaataa
    81541 cctcttcaaa atgacccaaa tgcaaaccaa ttttggtttc aatatgctcg ctatccaaaa
    81601 tggtataccg aaaattttgt ctcttcgtca gattttggat gcttatatcg agcaccaaaa
    81661 agaagtggtt gttcgtcgta cacgttttga taaggaaaaa gcggaagcgc gcgctcatat
    81721 cttagaaggt ctcttgattg cgctagacca tatcgacgaa gtgattcgta tcatccgtgc
    81781 tagtgaaacg gatgcggaag ctcaagctga gttgatgagc aagtttaagc tttctgaacg
    81841 tcaaagtcaa gctatccttg atatgcgtct tcgtcgtttg acaggtttgg aacgcgataa
    81901 gattcaatct gagtatgatg acctcttggc tctgattgcg gatttagcag atattcttgc
    81961 taagcctgaa cgtgtttctc aaattatcaa agacgaattg gatgaagtta aacgtaaatt
    82021 ttctgataaa cgccgtacag agttgatggt tggacagatc ttgagtctcg aggatgagga
    82081 cttgattgaa gaatcggatg tcttgattac cctttctaac agaggctaca ttaagcgttt
    82141 ggatcaggac gagttcactg ctcaaaaacg tgggggtcgt ggtgtccaag gaacgggagt
    82201 gaaagatgat gactttgttc gtgagttagt gtcaactagc acccatgatc atctgctctt
    82261 cttcacaaac aagggacgtg tctatcgtct taaaggttat gaaattcctg agtatggtcg
    82321 gactgccaaa gggctaccag tagtcaatct cttgaaattg gatgaagatg aaagtattca
    82381 gacggttatc aatgttgagt ctgatcgcag tgatgatgct tatctcttct ttacaacccg
    82441 tcacggtatt gtgaagagaa ctagtgttaa ggagtttgcc aatattcgtc aaaatggtct
    82501 caaagcgctg aatttaaagg atgaagatga gttaatcaat gtcttgttga cagaaggaga
    82561 tatggatatt atcattggta ccaagtttgg ttatgcagtt cgctttaatc aatcagccgt
    82621 tcgtggtatg agccgtatcg ccactggtgt gaaaggtgtt aaccttcgtg aaggagacac
    82681 agttgttggt gccagcttga ttactgatca agatgaggtt cttattatca cagaaaaagg
    82741 atatggtaag cgtacagtcg ctactgaata cccaacaaaa ggtcgtggtg gtaagggaat
    82801 gcagacagct aaaattaccg aaaaaaatgg cttgctggcc ggtcttatga ctgttcaagg
    82861 tgatgaggat ttgatgatta tcactgatac aggtgtcatg attcgaacca atcttgccaa
    82921 tatttcacaa acaggacgtg caactatggg agttaaagta atgcgcctgg atcaagatgc
    82981 tcagatagtg actttcacaa cggttgcggg ggcagaaaaa gaagaagttg ggacagaaaa
    83041 cgaaacagaa ggtgaagcat aatgtctcaa aaaaataata aaaagaaaaa caagcgaaaa
    83101 aatctgctga caaatatcct agcaggattt ctgatattac tgtcactggc tttgattttt
    83161 aatactcaaa ttcgaaatat tttcatagtc tggaatacca ataagtatca agttagccag
    83221 gtatcaaaag aaaaattaga agaaaatcag gatacagaag gcaattttga ctttgattct
    83281 gtcaaagcta tctcttcgga agctgttcta acttctcaat gggatgctca aaaattacca
    83341 gttattgggg gaattgcaat tcctgaattg gaaatgaatt tgccgatttt taaaggactt
    83401 gataatgtta atctcttcta cggagctggt acaatgaaac gcgagcaagt aatgggagaa
    83461 ggaaattata gtctagctag tcaccatatc tttggtgttg ataatgctaa taaaatgtta
    83521 ttttctcctt tagataatgc taaaaatggc atgaagattt atctaaccga taaaaataaa
    83581 gtttatactt atgaaatacg tgaagtcaaa cgtgtgacac cggatcgtgt tgatgaagtt
    83641 gatgatagag atggggtcaa tgaaatcaca ttagtaacct gtgaagacct tgctgctaca
    83701 gaacgtatta ttgtcaaagg tgatttgaaa gaaacaaaag attattcaca aacatctgat
    83761 gaaatcctaa cagctttcaa tcaaccatat aaacaatttt attaatacaa atcagtgaaa
    83821 tcatggattt cactgatttt ttaagatttt cataaaaata ta
//
LOCUS       DBEJHE010000006        81529 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC4 isolate 671759
            SAMN38261586-rid24793303.denovo.06, whole genome shotgun sequence.
ACCESSION   DBEJHE010000006 DBEJHE010000000
VERSION     DBEJHE010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261586
            Sequence Read Archive: SRR26833752
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 81529)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 81529)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576136.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576136.1
            Genome Coverage       :: 109x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 19:48:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,067
            CDSs (total)                      :: 2,029
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 131
            CDSs (without protein)            :: 131
            Pseudo Genes (ambiguous residues) :: 0 of 131
            Pseudo Genes (frameshifted)       :: 64 of 131
            Pseudo Genes (incomplete)         :: 59 of 131
            Pseudo Genes (internal stop)      :: 46 of 131
            Pseudo Genes (multiple problems)  :: 32 of 131
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..81529
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261586-rid24793303.denovo.06"
                     /strain="GPSC4"
                     /isolate="671759"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            1..1014
                     /locus_tag="ACL3EZ_000543"
                     /pseudo
     CDS             1..1014
                     /locus_tag="ACL3EZ_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(1142..1390)
                     /locus_tag="ACL3EZ_000544"
     CDS             complement(1142..1390)
                     /locus_tag="ACL3EZ_000544"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000155489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR0392166.1"
                     /translation="MASTSLQAPAKICFILIKLYSPYAFLSKYLGAILLSFFCYYAKE
                     IGCNNLTLSVWNDNEGALRFYQRQGMKPQETTMEMIID"
     gene            complement(1338..2420)
                     /locus_tag="ACL3EZ_000545"
     CDS             complement(1338..2420)
                     /locus_tag="ACL3EZ_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M24 family metallopeptidase"
                     /protein_id="HGR0392167.1"
                     /translation="MSKLQQILTYLESEKLDVAVVSDPVTINYLTGFYSDPHERQMFL
                     FVLADQEPLLFVPALEVERASSTVSFPVVGYVDSENPWQKIKHALPQLDFKRVAVEFD
                     NLILTKYHGLKTVFETAEFDNLTPRIQRMRLIKSADEVQKMMVAGLYADKAVHVGFDN
                     ISLDKTETDIIAQIDFAMKREGYEMSFDTMVLTGDNAANPHGIPAANKVENDALLLFD
                     LGVLVNGYASDMTRTVAVGKPDQFKKDIYNLTLEAQQAALDFIKPGVTAHEVDRAARE
                     VIEKAGYGEYFNHRLGHGIGMDVHEFPSIMEGNDMVIEEGMCFSVEPGIYIPGKVGVR
                     IEDCGVVTKDGFDLFTSTSKDLLYFD"
     gene            complement(2546..3328)
                     /gene="gatD"
                     /locus_tag="ACL3EZ_000546"
     CDS             complement(2546..3328)
                     /gene="gatD"
                     /locus_tag="ACL3EZ_000546"
                     /EC_number="6.3.5.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004359 - glutaminase activity [Evidence
                     IEA];
                     GO_function: GO:0140282 - carbon-nitrogen ligase activity
                     on lipid II [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipid II isoglutaminyl synthase subunit GatD"
                     /protein_id="HGR0392168.1"
                     /translation="MVYTSLSSKDSNYPYQLNIAHLYGNLMNTYGDNGNILMLKYVAE
                     KLGAHVTVDIVSLHDDFDENHYDIAFFGGGQDFEQSIIADDLPAKKESIDNYIQNDGV
                     VLAICGGFQLLGQYYVEASGKRIEGLGVMGHYTLNQTNNRFIGDIKIHNEDFDETYYG
                     FENHQGRTFLSDDQKPLGQVVYGNGNNEEKVGEGVHYKNVFGSYFHGPILSRNANLAY
                     RLVTTALKKKYGQDIQLPAYEDILSQEIAEEYSDVKSKADFS"
     gene            complement(3328..4671)
                     /gene="murT"
                     /locus_tag="ACL3EZ_000547"
     CDS             complement(3328..4671)
                     /gene="murT"
                     /locus_tag="ACL3EZ_000547"
                     /EC_number="6.3.5.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016881 - acid-amino acid ligase activity
                     [Evidence IEA];
                     GO_function: GO:0140282 - carbon-nitrogen ligase activity
                     on lipid II [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipid II isoglutaminyl synthase subunit MurT"
                     /protein_id="HGR0392169.1"
                     /translation="MNLKTTLGLLAGRSSHFVLSRLGRGSTLPGKVALQFDKDILQSL
                     AKNYEIVVVTGTNGKTLTTALTVGILKEVYGQVLTNPSGANMITGIATTFLTAKSSKT
                     GKNIAVLEIDEASLSRICDYIQPSLFVITNIFRDQMDRFGEIYTTYNMILDAIRKVPT
                     ATVLLNGDSPLFYKPTIPNPIEYFGFDLEKGPAQLAHYNTEGILCPDCQGILKYEHNT
                     YANLGAYICEGCGCKRPDLDYRLTKLVELTNNRSRFVIDGQEYGIQIGGLYNIYNALA
                     AVAIARFLGADSQLIKQGFDKSRAVFGRQETFHIGDKECTLVLIKNPVGATQAIEMIK
                     LAPYPFSLSVLLNANYADGIDTSWIWDADFEQITDMDIPEINAGGVRHSEIARRLRVT
                     GYPAEKITETSNLEQVLKTIENQDCKHAYILATYTAMLEFRELLASRQIVRKEMN"
     gene            complement(4770..6086)
                     /locus_tag="ACL3EZ_000548"
     CDS             complement(4770..6086)
                     /locus_tag="ACL3EZ_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000958936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016668 - oxidoreductase activity, acting
                     on a sulfur group of donors, NAD(P) as acceptor [Evidence
                     IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HGR0392170.1"
                     /translation="MLTYDLIVIGFGKAGKTLAGKLASAGKKVALVERSKAMYGGTCI
                     NIGCIPTKTLLVAAEKDLSFEEVIATKNTITGRLNGKNYATVAGTGVDIFDAEAHFLS
                     NKVIEIQAGDEKKELTAETIVINTGAVSNVLPIPGLATSKNIFDSTGIQSLDKLPEKL
                     GILGGGNIGLEFAGLYNKLGSKVTVLDALDTFLPRAEPSIAALAKQYMEEDGIELLQN
                     IHTTEIKNDGDQVLVVTEDETYRFDALLYATGRKPNVEPLQLENTDIELTERGAIKVD
                     KHCQTNVPGVFAVGDVNGGLQFTYISLDDFRVVYSYLAGDGSYTLEDRLNVPNTMFIT
                     PALSQVGLTESQAADLKLPYAVKEIPVAAMPRGHVNGDLRGAFKAVVNTETKEILGAS
                     IFSEGSQEIINIITVAMDNKIPYTYFTKQIFTHPTLAENLNDLFAI"
     gene            6279..7505
                     /locus_tag="ACL3EZ_000549"
     CDS             6279..7505
                     /locus_tag="ACL3EZ_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="OFA family MFS transporter"
                     /protein_id="HGR0392171.1"
                     /translation="MKSNRYIIAFAGVILHLMLGSTYAWSVYRNPIIEKTGWDQASVA
                     FAFSLAIFCLGLSAAFMGRLVEKFGPKVMGSLSAFLYAGGNILTGFAIDRQELWLLYL
                     AYGILGGLGLGAGYITPVSTIIKWFPDKRGLATGLAIMGFGFASLLTSPIAQHLIAGV
                     GIVETFYILGASYFIIMLLASQFIKRPNEQELAILSSSGKEKTASLTQGMAANQALKS
                     NRFYMLWIIFFINIACGLGLISAASPMAQEMAGLSTSHAAVMVGVLGIFNGFGRLLWA
                     SLSDYIGRPLTFSILLLVNLFFSLSLWLFTDSVLFVVAMSILMTCYGAGFSLIPAYLS
                     DIFGTKELAALHGYILTAWAMAGLAGPILLAETYKMAHSYTQTLFVFLILYSIALALS
                     YYLGRSIKKESQKPLT"
     gene            7704..9278
                     /locus_tag="ACL3EZ_000550"
     CDS             7704..9278
                     /locus_tag="ACL3EZ_000550"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HGR0392172.1"
                     /translation="MKFNELNLSADLLAEIEKAGFVEASPIQEQTIPLALEGKDVIGQ
                     AQTGTGKTAAFGLPTLEKIRIEEATIQALVIAPTRELAVQSQEELFRFGRSKGVKVRS
                     VYGGSSIEKQIKALKSGAHIVVGTPGRLLDLIKRKALKLQDIETLILDEADEMLNMGF
                     LEDIEAIISRVPENRQTLLFSATMPDAIKRIGVQFMKAPEHVKIAAKELTTELVDQYY
                     IRVKEQEKFDTMTRLMDVAQPELAIVFGRTKRRVDELTRGLKIRGFRAEGIHGDLDQN
                     KRLRVLRDFKNGNLDVLVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KSGQSITFVAPNEMGYLQIIENLTKKRMKGLKPASVEESFQSKKQVALKKIERDFADE
                     TIRANFEKFGKDARKLAAEFTPEELAMYILSLTVQDPDSLPEVEIAREKPLPFKPSGN
                     GFGGKAKGGRGGRRGDDRRERDRRGNGRRDEFKKGSRGNDRFDKEKRYRKDNKKPRNT
                     LSEKQTGFVIRNKGDK"
     gene            9543..10331
                     /gene="codY"
                     /locus_tag="ACL3EZ_000551"
     CDS             9543..10331
                     /gene="codY"
                     /locus_tag="ACL3EZ_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HGR0392173.1"
                     /translation="MAHLLEKTRKITSILKRSEEQLQDELPYNAITRQLADIIHCNAC
                     IINSKGRLLGYFMRYKTNTDRVEQFFQTKIFPDDYVQGANMIYETEANLPVEHDMSIF
                     PVESRDDFPDGLTTIAPIHVSGIRLGSLIIWRNDKKFEDEDLVLVEIASTVVGIQLLN
                     FQREEDEKNIRRRTAVTMAVNTLSYSELRAVSAILGELNGNEGKLTASVIADRIGITR
                     SVIVNALRKLESAGIIESRSLGMKGTYLKVLISDIFEEVKKRDY"
     gene            10331..10906
                     /locus_tag="ACL3EZ_000552"
     CDS             10331..10906
                     /locus_tag="ACL3EZ_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase family protein"
                     /protein_id="HGR0392174.1"
                     /translation="MTKALISIDYTEDFVADSGKLTAGAPAQAISDAISKVTRLAFER
                     GDYIFFTIDAHEENDCFHPESKLFPPHNLIGTSGRNLYGDLGIFYQEHGSDSRVFWMD
                     KRHYSAFSGTDLDIRLRERRVSTVILTGVLTDICVLHTAIDAYNLGYDIEIVKPAVAS
                     IWPENHQFALGHFKNTLGAKLVDENLNELSE"
     gene            10988..11073
                     /locus_tag="ACL3EZ_000553"
     tRNA            10988..11073
                     /locus_tag="ACL3EZ_000553"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:11022..11024,aa:Leu,seq:aag)
     gene            11356..12486
                     /locus_tag="ACL3EZ_000554"
     CDS             11356..12486
                     /locus_tag="ACL3EZ_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0392175.1"
                     /translation="MVELNLKNIYKKYPNSEHYSVEDFNLNIKDKEFIVFVGPSGCGK
                     STTLRMIAGLEDITEGTASIDGVVVNDVAPKDRDIAMVFQNYALYPHMTVYDNMAFGL
                     KLRKYSKEDINKRVQEAAEILGLKEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMD
                     EPLSNLDAKLRVSMRAEIAKIHRRIGATTIYVTHDQTEAMTLADRIVIMSATKNPAGT
                     GTIGRVEQIGTPQEVYKNPVNKFVAGFIGSPAMNFINVKLVGSEIVSDGFRLKVPEGA
                     LKVLREKGYEGKELIFGIRPEDVNAEPAFLETFPDCVVKATISVSELLGSESHLYCQV
                     GKDEFVAKVDARDYLQTGATVELGFDLNKAHFFDVETEKTIY"
     gene            complement(12609..12779)
                     /locus_tag="ACL3EZ_000555"
     CDS             complement(12609..12779)
                     /locus_tag="ACL3EZ_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002668516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0392176.1"
                     /translation="MEIKEQTRKLAVSYSKYSFEVADKTDEVSNHTYGKATLTWFEEI
                     FEEYKEHHNIDV"
     gene            12972..13754
                     /locus_tag="ACL3EZ_000556"
     CDS             12972..13754
                     /locus_tag="ACL3EZ_000556"
                     /EC_number="2.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001848902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGR0392177.1"
                     /translation="MKKKQRCSNVRAGHKFLAKLGKKRLRPGGKRATDWLIAEGGFSK
                     EKRILEVACNRGTTAIELAQRFGCKITAVDMDAQALEVAKKSAGTAGVAHLISFERAN
                     AMKLPYQDASFDIVINEAMLTMQADQAKKKCVMEYLRVLKPGGLLLTHDVLLKEAKES
                     IRQELSQAIHVNVGPLTQDGWEQVMIESGYCDVKVLTGEMTLMKLSGMIYDEGWLGTL
                     KICVNACKKENRKQFLTMYKMFAKNKQKLGFIAMASYKSSKR"
     gene            13841..14353
                     /locus_tag="ACL3EZ_000557"
     CDS             13841..14353
                     /locus_tag="ACL3EZ_000557"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003999 - adenine
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0006168 - adenine salvage [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HGR0392178.1"
                     /translation="MNLKDYIATIENYPKEGITFRDISPLMADGNAYSYAVREIVQYA
                     TDKKVDMIVGPEARGFIVGCPVAFELGIGFAPVRKPGKLPREVISADYEKEYGVDTLT
                     MHADAIKPGQRVLIVDDLLATGGTVKATIEMIEKLGGVMAGCAFLVELDELNGREKIG
                     DYDYKVLMHY"
     gene            14535..15479
                     /gene="metA"
                     /locus_tag="ACL3EZ_000558"
     CDS             14535..15479
                     /gene="metA"
                     /locus_tag="ACL3EZ_000558"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008899 - homoserine O-succinyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0019281 - L-methionine biosynthetic process
                     from homoserine via O-succinyl-L-homoserine and
                     cystathionine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HGR0392179.1"
                     /translation="MPIRIDKKLPAVEILRTENIFVMDDQRAAHQDIRPLKILILNLM
                     PQKMVTETQLLRHLANTPLQLDIDFLYMESHRSKTTRSEHMETFYKTFPEVKDEYFDG
                     MIITGAPVEHLPFEEVDYWEEFRQMLEWSKTHVYSTLHICWGAQAGLYLRYGVEKYQM
                     DSKLSGIYPQDTLKEGHLLFRGFDDSYVSPHSRHTEISKEEVLNKTNLEILSEGPQVG
                     VSILASRDLREIYSFGHLEYDRDTLAKEYFRDRDAGFDPHIPENYFKDDDVNQVPCLC
                     WSSSAALFFSNWVNHAVYQETPFDWRKIEDDASAYRYL"
     gene            15488..16165
                     /locus_tag="ACL3EZ_000559"
     CDS             15488..16165
                     /locus_tag="ACL3EZ_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006269 - DNA replication, synthesis of
                     primer [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HGR0392180.1"
                     /translation="MTYLDAFKSGTLVLPSALLLHFKELFPSSDDFLVWQFFYLQNTT
                     GLEEISPSQIAERIGKEISDVNQSISNLTERGLLQYRTIELNGEIELLFDASLALERL
                     DDLFGAVHSSSDQLTPQNQLKDLVETFQQELGRLLTPFEIEDLTKTLKEDGTSADLIK
                     EALREAVLNGKPNWKYIQAILRNWRHEGIKSVAQIEAKRAEREASNPQLTQVSADFIN
                     AMDLWKD"
     gene            16263..17021
                     /gene="tpiA"
                     /locus_tag="ACL3EZ_000560"
     CDS             16263..17021
                     /gene="tpiA"
                     /locus_tag="ACL3EZ_000560"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004807 - triose-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HGR0392181.1"
                     /translation="MSRKPFIAGNWKMNKNPEEAKAFVEAVASKLPSSDLVEAGIAAP
                     ALDLTTVLAVAKGSNLKVAAQNCYFENAGAFTGETSPQVLKEIGTDYVVIGHSERRDY
                     FHETDEDINKKAKAIFANGMLPIICCGESLETYEAGKAAEFVGAQVSAALAGLTAEQV
                     AASVIAYEPIWAIGTGKSASQDDAQKMCKVVRDVVAADFGQEVADKVRVQYGGSVKPE
                     NVASYMACPDVDGALVGGASLEAESFLALLDFVK"
     gene            17059..18564
                     /gene="lytC"
                     /locus_tag="ACL3EZ_000561"
     CDS             17059..18564
                     /gene="lytC"
                     /locus_tag="ACL3EZ_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078138769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase LytC"
                     /protein_id="HGR0392182.1"
                     /translation="MSVTFFIGEERLKTKIGLASICLLGLATSHVAANETEVAKTSQD
                     TTTASSSSEQNQSSNKTQTSTEVQTNAAAHWYGDYYVKDDGSKAQSEWIFDNYYKAWF
                     YINSDGRYSQNEWHGNYYLKSGGYMAQNEWIYDSNYKSWFYLKSDGAYAHQEWQLIGN
                     KWYYFKKWGYMAKSQWQGSYFLNGQGAMMQNEWLYDPAYSAYFYLKSDGTYANQEWQK
                     VGGKWYYFKKWGYMARNEWQGNYYLTGSGAMATDEVIMDGARYIFAASGELKEKKDLN
                     VGWVHRDGKRYFFNNREEQVGTEHAKKIIDISEHNGRINDWKKVIDENEVDGVIVRLG
                     YSGKEDKELAHNIKELNRLGIPYGVYLYTYAENETDAENDAKQTIELIKKYNMNLSYP
                     IYYDVENWEYVNKSKRAPSDTDTWVKIINKYMDTMKQAGYQNVYVYSYRSLLQTRLKH
                     PDILKHVNWVAAYTNALEWENPYYSGEKGWQYTSSEYMKGIQGRVDVSVWY"
     gene            19060..19578
                     /locus_tag="ACL3EZ_000562"
     CDS             19060..19578
                     /locus_tag="ACL3EZ_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HGR0392183.1"
                     /translation="MVELKKEAVKDVTSLTKAAPVALAKTKEVLNQAVADLYVAHVAL
                     HQVHWYMHGRGFLVWHPKMDEYMEALDGQLDEISERLITLGGSPFSTLTEFLQNSEIE
                     EEAGEYRNVEESLERVLVIYRYLSELFQKGLDVTDEEGDDVTNGIFAGAKTETDKTIW
                     MLAAELGQAPGL"
     gene            19708..20214
                     /locus_tag="ACL3EZ_000563"
     CDS             19708..20214
                     /locus_tag="ACL3EZ_000563"
                     /EC_number="1.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004146 - dihydrofolate reductase activity
                     [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HGR0392184.1"
                     /translation="MTKKIVAIWAQDKEGVIGKENRLPWHLPAELQHFKETTLNHAIL
                     MGRVTFDGMGRRLLPKRETLILTRNPEEKIDGVATFQDVQSVLDWYQAQEKNLYIIGG
                     KQIFQAFEAYLDEVIVTHIHARVEGDTYFPGELDLSLFETVSSKFYAKDEKNPYDFTI
                     QYRKRKEV"
     gene            20214..20384
                     /locus_tag="ACL3EZ_000564"
     CDS             20214..20384
                     /locus_tag="ACL3EZ_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000442275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0392185.1"
                     /translation="MERSLFGLFTAFLCFICFLAGAQAFRKKRYGLSILLWLNAFTNL
                     VNSIHAFYMTLF"
     gene            20416..21648
                     /gene="clpX"
                     /locus_tag="ACL3EZ_000565"
     CDS             20416..21648
                     /gene="clpX"
                     /locus_tag="ACL3EZ_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002874765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HGR0392186.1"
                     /translation="MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQE
                     IIREELVEEVLADLSEVPKPIELLHILNHYVIGQDRAKRALAVAVYNHYKRINFHDTR
                     EESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
                     ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGT
                     VASVPPQGGRKHPQQEMIQVDTKNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAI
                     DENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVRILKEPRNALVKQYQ
                     TLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLV
                     RITKETVDGTDKPILETA"
     gene            21657..22244
                     /gene="yihA"
                     /locus_tag="ACL3EZ_000566"
     CDS             21657..22244
                     /gene="yihA"
                     /locus_tag="ACL3EZ_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002915299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTP-binding protein
                     YihA/YsxC"
                     /protein_id="HGR0392187.1"
                     /translation="MELNTHNAEILLSAANKSHYPQDELPEIALAGRSNVGKSSFINT
                     MLNRKNLARTSGKPGKTQLLNFFNIDDKMRFVDVPGYGYARVSKKEREKWGCMIEEYL
                     TTRENLRAVVSLVDLRHDPSADDVQMYEFLKYYEIPVIIVATKADKIPRGKWNKHESA
                     IKKKLNFDPSDDFILFSSVSKAGMDEAWDAILEKL"
     gene            22255..22635
                     /locus_tag="ACL3EZ_000567"
     CDS             22255..22635
                     /locus_tag="ACL3EZ_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HGR0392188.1"
                     /translation="MAKTIHTDKAPKAIGPYVQGKIVGNLLFASGQVPLSPETGEIVG
                     ENIQEQTEQVLKNIGAILAEAGTDFDHVVKTTCFLSDMNDFVPFNEVYQTAFKEEFPA
                     RSAVEVARLPRDVKVEIEVIAEIG"
     gene            22687..23577
                     /gene="rapZ"
                     /locus_tag="ACL3EZ_000568"
     CDS             22687..23577
                     /gene="rapZ"
                     /locus_tag="ACL3EZ_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HGR0392189.1"
                     /translation="MTKKQLHLVIVTGMSGAGKTVAIQSFEDLGYFTIDNMPPALLPK
                     FLQLVEIKEDNPKLALVVDMRSRSFFSEIQAVLDELENQDGLDFKILFLDAADKELVA
                     RYKETRRSHPLAADGRILDGIKLERELLAPLKNMSQNVVDTTELTPRELRKTLAEQFS
                     DQEQAQSFRIEVMSFGFKYGIPIDADLVFDVRFLPNPYYLPELRNQTGVDEPVYDYVM
                     NHPESEDFYQHLLALIEPILPSYQKEGKSVLTIAMGCTGGQHRSVAFAKCLAQDLSKN
                     WSVNEGHRDKDRRKETVNRS"
     gene            23574..24551
                     /locus_tag="ACL3EZ_000569"
     CDS             23574..24551
                     /locus_tag="ACL3EZ_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HGR0392190.1"
                     /translation="MRKPKITVIGGGTGIPVILKSLREKDVEIAAIVTVADDGGSSGE
                     LRKNMQQLTPPGDLRNVLVAMSDMPKFYEKVFQYRFSEDAGAFAGHPLGNLIIAGLSE
                     MQGSTYNAMQLLSKFFHTTGKIYPSSDHPLTLHAVFQDGTEVAGESHIVDHRGIIDNV
                     YVTNALNDDTPLASRRVVQTILESDMIVLGPGSLFTSILPNIVIKEIGRALLETKAEI
                     AYVCNIMTQRGETEHFTDSDHVEVLHRHLGRPFIDTVLVNIEKVPQEYMNSNRFDEYL
                     VQVEHDFVGLCKQVSRVISSNFLRLENGGAFHDGDLIVDELMRIIQVKK"
     gene            24548..25459
                     /gene="whiA"
                     /locus_tag="ACL3EZ_000570"
     CDS             24548..25459
                     /gene="whiA"
                     /locus_tag="ACL3EZ_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0043937 - regulation of sporulation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HGR0392191.1"
                     /translation="MSFTVAVKEEILGQHHLSRHELSAIIKMSGSIGLSTSGLTLSVV
                     TENAKLARHLYESFLHFYEIKSEIRHYQRSNLRKNRVYTVFTDEKVQDLLSDLHLADS
                     FFGLETGIDEAILSDEEAGRAYLCGAFLANGSIRDPESGKYQLEISSVYLDHAQGIAS
                     LLQQFLLDAKVLERKKGAVTYLQRAEDIMDFLIVIGAMQARDDFERVKILRETRNDLN
                     RANNAETANIARTVSASMKTINNISKIKDIMGLENLPVDLQEVAQLRIQHPDYSIQQL
                     ADSLSTPLTKSGVNHRLRKINKIADEL"
     gene            complement(25493..26458)
                     /locus_tag="ACL3EZ_000571"
     CDS             complement(25493..26458)
                     /locus_tag="ACL3EZ_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000081018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HGR0392192.1"
                     /translation="MSQLYDITIVGGGPVGLFAAFYAHLRQAKVQIIDSLPQLGGQPA
                     ILYPEKEILDVPGFPNLTGEELTNRLIEQLNGFDTPIHLNETVLEIDKQEEFAITTSK
                     GSHLTKTVIIAMGGGAFKPRPLELEGVEGYENIHYHVSNIQQYAGKKVTILGGGDSAV
                     DWALAFEKIAPTTLVHRRDNFRALEHSVQALQESSVTIKTPFAPSQLLGNGKTLDKLE
                     ITKVKSDETETIDLDHLFVNYGFKSSVGNLKNWGLDLNRHKIIVNSKQESSQAGIYAI
                     GDCCYYDGKIDLIATGLGEAPTAVNNAINYIDPEQKVQPKHSTSL"
     gene            26594..27451
                     /gene="cdaA"
                     /locus_tag="ACL3EZ_000572"
     CDS             26594..27451
                     /gene="cdaA"
                     /locus_tag="ACL3EZ_000572"
                     /EC_number="2.7.7.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001867651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004016 - adenylate cyclase activity
                     [Evidence IEA];
                     GO_process: GO:0006171 - cAMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diadenylate cyclase CdaA"
                     /protein_id="HGR0392193.1"
                     /translation="MNFQQLSNLQYWTSLFASPWTIAINLIDILIVAYILYHFTKAIA
                     GTKIMILVRGVLVFILAQILANMIGLTTISWLINQIITYGVIAAVVIFSPEIRTGLER
                     LGRATDFFSNAPISAEEQMIRAFVKSVEYMSPRKIGALVAIQRVRTLQEYISTGIPLD
                     AKISAELLINIFIPNTPLHDGAVIIKEERIAVTSAYLPLTKNTGISKEFGTRHRAAIG
                     LSEVSDALTFVVSEETGGISITYNGRFKHNLTLDEFETELREILLPKEEVGLSFKERL
                     LGGWKHEKK"
     gene            27438..28217
                     /locus_tag="ACL3EZ_000573"
     CDS             27438..28217
                     /locus_tag="ACL3EZ_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CdaR family protein"
                     /protein_id="HGR0392194.1"
                     /translation="MKKNSLYIISSLFFACVLFVYATATNFQNSTSARQVKTETYTNT
                     VTNVPIDIRYNSDKYFISGFASEVSVVLTGANRLSLASEMQESTRKFKVTADLTDAGV
                     GTIEVPLSIEDLPNGLTAVATPQKITVKIGKKAQKDKVKIVPEIDPSQIDSRVQIENV
                     MVSDKEVSITSDQETLDRIDKIIAVLPTSERITGNYSGSVPLQAIDRNGVVLPAVITP
                     FDTIMKVTTKPVAPSSSTSNSSTSSSSETSSSTKATSSKTN"
     gene            28241..29593
                     /gene="glmM"
                     /locus_tag="ACL3EZ_000574"
     CDS             28241..29593
                     /gene="glmM"
                     /locus_tag="ACL3EZ_000574"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008966 - phosphoglucosamine mutase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HGR0392195.1"
                     /translation="MGKYFGTDGVRGEANLELTPELAFKLGRFGGYVLSQHETEAPKV
                     FVGRDTRISGEMLESALVAGLLSVGIHVYKLGVLATPAVAYLVETEGASAGVMISASH
                     NPALDNGIKFFGGDGFKLDDEKEAEIEALLDAEEDTLPRPSAEGLGILVDYPEGLRKY
                     EGYLVSTGTPLDGMKVALDTANGAASTSARQIFADLGAQLTVIGETPDGLNINLNVGS
                     THPEALQEVVKESGSAIGLAFDGDSDRLIAVDENGDIVDGDKIMYIIGKYLSEKGQLA
                     QNTIVTTVMSNLGFHKALNREGINKAVTAVGDRYVVEEMRKSGYNLGGEQSGHVILMD
                     YNTTGDGQLSAVQLTKIMKETGKSLSELAAEVTIYPQKLVNIRVENVMKEKAMEVPAI
                     KAIIEKMEEEMAGNGRILVRPSGTEPLLRVMAEAPTTEEVDYYVDTITDVVRAEIGID
                     "
     gene            29667..30041
                     /locus_tag="ACL3EZ_000575"
     CDS             29667..30041
                     /locus_tag="ACL3EZ_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HGR0392196.1"
                     /translation="MNLKREQEFVSQYHFDARNFEWENENGAPETKVDVNFQLLQHDQ
                     ENQVTSLIVILSFMIVFDKFVISGTISQVNHIDGRIVNEPSELNQEEVETLARPCLNM
                     LNRLTYEVTEIALDLPGINLEF"
     gene            30043..30891
                     /locus_tag="ACL3EZ_000576"
     CDS             30043..30891
                     /locus_tag="ACL3EZ_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005504 - fatty acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HGR0392197.1"
                     /translation="MKLAVFTDSSAYLSEETLQREDLFVLDIPVNIDGEEYVEGINLS
                     AEEFYQKMAQASELPKTSQPSIAKLDEILTSLKEQGYTHALGLFLSSGISGFYQNIQY
                     MVDDYEGLTIAFPDTLITSAPLGIMVESVFNWRDQGDDFASIQDKLAIQISRTSAFIM
                     VDDLDHLVKGGRLSNGAAILGNLLSIKPILYFNDQGVIEVYEKVRTEKKATKRLIEII
                     KETTASGQYRVIVIHGNDPEKAEELRQHLLDFGLGSDVSLATFGSVIGTHLGAGSIAL
                     GYIPVI"
     gene            31157..31924
                     /gene="dapB"
                     /locus_tag="ACL3EZ_000577"
     CDS             31157..31924
                     /gene="dapB"
                     /locus_tag="ACL3EZ_000577"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008839 - 4-hydroxy-tetrahydrodipicolinate
                     reductase [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HGR0392198.1"
                     /translation="MSIRVIIAGFKGKMGQAACQMVLPDSDLDLVAVLDPFESESEWQ
                     GIPVFKDKADLAGFEADVWVDFTTPAVAYENTRFALENGFAPVVGTTGFTSEEIAELK
                     EFSRAQDLGGLIAPNFALGAVLLMQFATQAAKYFPNVEIIELHHDKKKDAPSGTAIKT
                     AELMAEVRESIQQGAADEEELIAGARGADFDGMRIHSVRLPGLVAHQEVIFGNQGEGL
                     TLRHDSYDRISFMTGVNLGIKEVVKRHELVYGLEHLL"
     gene            31921..33120
                     /locus_tag="ACL3EZ_000578"
     CDS             31921..33120
                     /locus_tag="ACL3EZ_000578"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0001680 - tRNA 3'-terminal CCA addition
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HGR0392199.1"
                     /translation="MRLTQMPSEFQKALPVLEKIKEAGFEAYFVGGSVRDALLHSPIH
                     DVDIATSSYPEETKQIFPRTADIGIEHGTVLVLDGDEEYEVTTFRTEDVYVDYRRPSA
                     VSFVRSLEEDLKRRDFTVNAFALDETGEIVDLFHGLEDLEKQVLRAVGVASERFNEDA
                     LRIMRGFRFQASLGFALEPETFKAMKTLTPLLENISVERTFVEFDKLLLAPFWRRGLA
                     SMIESQAYDYLPDMASSQNKLNRLFDLETDFTFESSEQAWAALLWALEIENAQSFLKS
                     WKTSRQFAKQVQDLLIILALRENGELSKRDCYRFDIDLLLQAENLRQARGKEVNPQAI
                     TEKYQSLTIHDKKEIQINGDILIKEYGYQPGPDLGEILTEIEFAIVDGELENNREAIH
                     AYLREKK"
     gene            33117..34987
                     /locus_tag="ACL3EZ_000579"
                     /pseudo
     CDS             33117..34987
                     /locus_tag="ACL3EZ_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001279112.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
     gene            complement(35130..36314)
                     /gene="mntE"
                     /locus_tag="ACL3EZ_000580"
     CDS             complement(35130..36314)
                     /gene="mntE"
                     /locus_tag="ACL3EZ_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDF family manganese efflux transporter MntE"
                     /protein_id="HGR0392200.1"
                     /translation="MKQSISNLKLAERGAIISISTYLILSAAKLAAGHLLHSSSLVAD
                     GFNNVSDIIGNVALLIGIRMARQPADRDHRFGHWKIEDLASLITSIIMFYVGFDILRD
                     TIQKILSREETVIDPLGATLGIISAAIMFVVYLYNTRLSKKSNSKALKAAAKDNLSDA
                     VTSLGTAIAILASSFNYPIVDKLVAIIITFFILKTAYDIFIESSFSLSDGFDDRLLED
                     YQKAIMEIPKISKVKSQRGRTYGSNIYLDITLEMNPDLSVFESHEIADQVESMLEERF
                     GVFDTDVHIEPAPIPEDEILDNVYKKLLMREQLIDQGNQLEELLTDDFVYIRQDGEQM
                     DKEAYKTKKELNSAIKDIQITSISQKTKLICYELDGIIHTSIWRRHETWQNIFHQETK
                     KE"
     gene            36618..39314
                     /locus_tag="ACL3EZ_000581"
     CDS             36618..39314
                     /locus_tag="ACL3EZ_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HGR0392201.1"
                     /translation="MSKEQKRQAFYTQSPEEVLQAVDATEQGLSSSEAEKRLAEFGHN
                     ELEEGEKRSILVKFIEQFKDLMIIILVAAAILSVVTSGGEDIADAIIILAVVIINAAF
                     GVYQEGKAEEAIEALKSMSSPVARVLRDGHMAEIDSKELVPGDIVALEAGDVVPADLR
                     LLEANSLKIEEAALTGESVPVEKDLSVELATDAGIGDRVNMAFQNSNVTYGRGMGVVV
                     NTGMYTEVGHIAGMLQDADETDTPLKQNLNNLSKVLTYAILVIALITFVVGVFIQGKN
                     PLGELLTSVALAVAAIPEGLPAIVTIVLSLGTQVLAKRHSIVRKLPAVETLGSTEIIA
                     SDKTGTLTMNKMTVEKVFYDAVLHDSADDIELGLEMPLLRSVVLANDTKIDVEGNLIG
                     DPTETAFIQYALDKGYDVKGFLEKYPRVAELPFDSDRKLMSTVHPLPDGRFLVAVKGA
                     PDQLLKRCLLRDKAGDIAPIDEKVTNLIHTNNSEMAHQALRVLAGAYKIIDSIPENLT
                     SEELENDLIFTGLIGMIDPERPEAAEAVRVAKEAGIRPIMITGDHQDTAEAIAKRLGI
                     IDANDTEGHVLTGAELNELSDEEFEKVVGQYSVYARVSPEHKVRIVKAWQKQGKVVAM
                     TGDGVNDAPALKTADIGIGMGITGTEVSKGASDMILADDNFATIIVAVEEGRKVFSNI
                     QKTIQYLLSANTAEVLTIFLSTLFGWDVLQPVHLLWINLVTDTFPAIALGVEPAEPGV
                     MNHKPRGRKASFFSGGVLSSIIYQGVLQAALVMSVYGLAIAYPVHVGDNHAIHADALT
                     MAFATLGLIQLFHAYNVKSVYQSILTVGPFKSKTFNWSILVSFILLMATIVVEPLEGI
                     FHVTKLDLSQWGIVMAGSFSMIIIVEIVKFIQRKLGFDKNAI"
     gene            39327..40118
                     /gene="yghU"
                     /locus_tag="ACL3EZ_000582"
     CDS             39327..40118
                     /gene="yghU"
                     /locus_tag="ACL3EZ_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0006749 - glutathione metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-dependent disulfide-bond
                     oxidoreductase"
                     /protein_id="HGR0392202.1"
                     /translation="MSAYQLPTVWQDEASNQGAFTGLNRPTAGARFEQNLPKGEQAFQ
                     LYSLGTPNGVKVTILLEELLEAGFKEAAYDLYKIAIMDGDQFGSDFVKLNPNSKIPAL
                     LDQSGTENVRVFESAHILLYLAEKFGAFLPSNPVEKVEVLNWLFWQAGAAPFLGGGFG
                     HFFNYAPEKLEYPINRFTMEVKRQLDLLDKELAQKPYIAGNDYTIADIAIWSWYGQLV
                     QGNLYQGSAKFLDASSYQNLVKWAEKIANRPAVKRGLEVTYTEIK"
     gene            40234..40644
                     /locus_tag="ACL3EZ_000583"
     CDS             40234..40644
                     /locus_tag="ACL3EZ_000583"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HGR0392203.1"
                     /translation="MEKKIVKDILFLSQVSQPASQEDLYLARDLQDTLLANRDTCVGL
                     AANMIGVQKRVIIFNLGLVPVVMFNPVLLSFEGSYEAEEGCLSLVGVRSTKRYETTRL
                     AYRDSKWQEQTITLTGFPAQICQHELDHLEGRII"
     gene            40656..42251
                     /locus_tag="ACL3EZ_000584"
     CDS             40656..42251
                     /locus_tag="ACL3EZ_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0392204.1"
                     /translation="MKRIVFELIFIATTWYIFLPPLNLTSWEFLFFLCGHLLVVAILF
                     GFGKGINLVKTVHVRHGKAEAALNLEGFKINRLGKILLASIGGILLLAALVSLVTSSM
                     FQAKNYANVVTVTEKDFTEFPRSDTSKVPILDRSTAEKIGDRYLGSLTDKVSQYVAAD
                     TYTQLTIDGKPYRVTPLEYADPIKWFNNQAKGIGEYIKVDMVTGNADLVDLKTPIKYS
                     DSEYFNRDVKRHLRLKYPTKIFKTPSFEVDDEGNPFYVATVYQKQFGLAVPRPASVII
                     LDATNGETKEYSLSDVPEWVDRIYPAEETIEQINYNGKYKDGFLNAMISKKNVTQTTN
                     GYNYLSIGNDIYLYTGVTSANADESNLGFILENMRTGEITKYSLASATEESARESAEG
                     AVQEKSYKATFPILINLNDKPLYIMGLKDNAGLVKEYALVDAVEYQNVIVATTVEEML
                     SKYANKNDLEIDNATTESIKGVVADLKSAVIKGDTVYFFKVDGKIYKVKASVSDDLPY
                     LENGKTFEGQVGKDNYLKTFKVQ"
     gene            42418..42582
                     /locus_tag="ACL3EZ_000585"
     CDS             42418..42582
                     /locus_tag="ACL3EZ_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000508323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YczI family protein"
                     /protein_id="HGR0392205.1"
                     /translation="MGFYLMVASMLLGLLALKIGFSQFKEKKDKFLSILTSLAGTALV
                     LVAVWLGWPK"
     gene            42661..43389
                     /gene="yaaA"
                     /locus_tag="ACL3EZ_000586"
     CDS             42661..43389
                     /gene="yaaA"
                     /locus_tag="ACL3EZ_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HGR0392206.1"
                     /translation="MKILIPTAKEMNTDLPSIEAIPLKPESQTVLDALALYSASQLES
                     FYKVSAEKAAEEFQNIQALKRQTAQHYPALKLFDGLMYRNIKRDKLTEAEQDYLENHV
                     FITSALYGVVPALSPMAPHRLDFLMKLKVAGKTLKSHWKAVYDEALKKEEVIFSLLSS
                     EFETVFSKEIRAKMVTFKFMEDRGGQLKIHSTISKKARGAFLTALIENQVQTVGEARR
                     LNFAGFVYREDLSQPQGLVFVKEV"
     gene            complement(43440..44924)
                     /locus_tag="ACL3EZ_000587"
     CDS             complement(43440..44924)
                     /locus_tag="ACL3EZ_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003096885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M protein trans-acting positive regulator PRD
                     domain-containing protein"
                     /protein_id="HGR0392207.1"
                     /translation="MRNLLSTKVQRQLRLMETLIQNRNWMKLHELAEKLGCTERILKS
                     DLNELRIAFPSINIQSSVNGIMIDLEVNTSVEDIYQYFLANSQSFQLLEYMFFNEGLP
                     IYRTIENLYFSSANLYRLGRNITKVLSSQFQIELSFTPSEIRGNEIDIRYFFAQYFSE
                     RYYFLDWPFPDLPEEDLTEFADFFYKITNYPMRFSIYRMYKLMIAISIHRVKNGHFID
                     LPNHFYKEYYPLLKSIPNFQETLAYFSKHFGLEMTPDTIAQIFISFLQNDIFLDPQEF
                     FNSLEDNSQARYSYQLLSQILERLSKQYKITFTNHDELIWHLHNTAFFERQEIFSTPI
                     LFEQKALTIKKFEVYFPDFMGSARQELAQYRQAIGQHDHPEQLEHLMYTILTHAENLS
                     TQLLENRPPIKVLIISNFDHAISLTFVDMLSYYCNNRFTFDIWDELKTSPEILNQTDY
                     DIIVSNFYIPGITKKFICRNHLSIMNLVNHLNTLSNEIHLSNTL"
     gene            45140..51892
                     /locus_tag="ACL3EZ_000588"
     CDS             45140..51892
                     /locus_tag="ACL3EZ_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HGR0392208.1"
                     /translation="MKHSHKKSFDWYSMQQRYSIRKYYFGAASVLLGTALVLGVAASV
                     QTVQAEENKQETTNSISVGRGEAATKPAEVSASNKEKTYAAPTVANPVETTPVKTEEV
                     TKPAEKVEEAKDKKEEVTHQDAVDKSKLLTALSRAKKLESKLYTEASAANLQTSIQAG
                     QSLLGKADATEAELSAAESSIQSFIIGLELRSNSNKETVSETPVAKKADAVESKEGAK
                     PAATTERSAVDSAILPTSTADKVETTSAPASINEILKLGLSLSDARQNPAIRKENVNR
                     GYSGFRAASNPANPIVSGSGNTVAFADISQGGRSYSFRGYGNSRGGNSIHYDVTTVRS
                     GNSVNFTISYSAPGDSREFVNNNFILDKGDGFGNPSNATITSSNPRVREQSKSISQGA
                     NYVSHSGYSMTSAISTNTEQTIRFSLPIINLNGDLSVRLKPVTFNVDQGGGGAATSND
                     PYSNSNYYYRANPLYLDANPYGGTNNKTVSEDIDFQTVYLPTSKLPEGQTRLVREGEK
                     GQRQITYKVHRFGNETLLGLPISNSVTKEAKPRIMQIGVAKDLIDTVKPRVDQNKVGD
                     TNNLTFYLDNDGNGVYTEGVDELVQKIAIKDGAKGEKGDQGERGLTGAKGEKGDRGER
                     GLTGAQGAKGEKGDRGERGLTGAQGAKGEKGAQGERGLTGAKGEKGDQGERGLTGAQG
                     EKGDRGERGLTGAKGEKGAQGQAGRDGVTPTVTVKDNKNDGTHTITINDGRGNVTSTV
                     VRDGFDGASPLVATQRNDADKTTTVIFYYDKNGNNELDASDKKLKEVVIADGAKGEKG
                     DKGEQGLQGRDGEQGPKGEDGKTPTVKVTDGQDGTHTITINDGKGGITTTVVRDGFDG
                     ASPLVSTHRNEADKTTTVIFYYDLNDNNQFDEGDTKLKEVVIADGKQGPKGDKGDNGK
                     DGFTPEVTVTDNNNGTHTITITQPDNRPSLTTIVKNGEDGKTPKVKAERDDAKKQTTL
                     TFYIDKDGDGSYTAGKDELVQTTVVKDGQDGAAGASGRDGKEVLNGKVDPTTEGKDGD
                     TFVNTQTGDVFVKKGNTWEPAGNIKGPKGDKGADGAKGEKGAQGERGLTGAQGVKGEK
                     GDQGERGLTGSKGEKGDQGERGLTGAQGAKGDKGEQGLQGRDGAQGPKGADGQRGPAG
                     PQGPKGEQGNPGTPGKDGKSLIAVKNGTETKVYVEDPARPGQPLNPNQPLATITDGRN
                     GTNGQSPTITATRSVQNGKNGVLVTITPVGGRPQTTFVEDGQKGADGKTPTVTITEGQ
                     NGTHTLTVHNPGSPDVTTTIRDGATGQAGRDGKDVLNGKVNPQPNQGKNGDKYINTET
                     GDVYVKNNGNWDKEGNIKGPKGDKGADGAKGEKGDQGERGLTGAQGAKGADGAVGRDG
                     RDGKDVLNGKANPEAHQGKDGDKYVNTETGDVFVKNNGNWDKEGNIKGPKGDKGERGE
                     DGKTPEVTVTPGKDGHSTDITFTVPGKDPVTVNVKDGENGLNGKTPKVDLLRVQGKNG
                     NPSHTIVTFYTDENNDGKYTPGTDELLGSEMIKDGAKGADGRDGKSLLTVKDGKETKV
                     YQEDPANPGQPLNPEKPLAVIRDGVDGKSPTVTAVRKDEAGHKGVEITVDNHDGSQPT
                     TVFVQDGAKGETGATGQDGQTPTITTQRGQDGQSTVVTITTSGKDPVTFTVKDGKNGK
                     DGRAPKIKVEDITSPSRIRRDTDAAATPTRNGIRVTVYDDVNDNGVYDEGVDKVLNSK
                     DIYNGIDGRDGSAPTITTKDNGDGTHTITVQNPDGSESTTVVKDGKDGKTANITTTEN
                     PDGSHTITVTNPDGSTKETVVKNGKDGKTPKVEVTDNNDGTHTVKVTDGDGNVTNAII
                     KDGKDGKAATATTTENPDGSHTVTITNPDGTKNEFVVKNGRDGVDGRTPTASVRDNGD
                     GSHTIVITNPEGVTTETTVRDGKSPKVTITDEQNGTHKISVLNGDGTTTTTTVRDGRE
                     PKLEVIDNNDGSHTIKVTGADGKGTTTTIFDGKSPKANIVDNGDGTHTLTIVDSDGRE
                     YKSIIKDGKDGKDSVSPTVTVKNNNDGTHVVTITNPDGSKTEMVIKDGKDGKSPKVSV
                     EDNGDGSHTITIINSDGTVTKTVIKDGRDGRDGRDGKDGKDGKDGKCGCQDKPVTPSN
                     DKPVPPTPNVPTPEVPVKPVPAQPTPNVPTPEVPVQPTPAVPTPEVPVKPVPAVPEQP
                     VVPTPAQPATPVNANPVAPTTGKENRGDKLPETGSQSDYISVLLGSGILLSLYVGRRK
                     EA"
     gene            complement(52129..52677)
                     /locus_tag="ACL3EZ_000589"
     CDS             complement(52129..52677)
                     /locus_tag="ACL3EZ_000589"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008752 - FMN reductase (NAD(P)H) activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0052873 - FMN reductase (NADPH) activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent FMN reductase"
                     /protein_id="HGR0392209.1"
                     /translation="MSKKVLFIVGSLRQGSFNHQMALEAEKALAGKAEVSYLDYSALP
                     LFSQDLEVPTHPAVAAAREAVLVADAIWIFSPVYNFSIPGTVKNLLDWLSRALDLSDT
                     RGVSALQDKFVTVSSVANAGHDQLFAIYKDLLPFIRTQGVGDFTAARVNDSAWADGKL
                     VLEETVLNSLEKQAQDLVEAIQ"
     gene            52998..53486
                     /locus_tag="ACL3EZ_000590"
     CDS             52998..53486
                     /locus_tag="ACL3EZ_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HGR0392210.1"
                     /translation="MKKRQNKAKNNLLWQYGLGMTILFVVISASFLYMVSLSMKPYQT
                     AKSEGEKLAQQYAGLEQADQVDLYNGLESYYSVLGRNKQQEALAVLIGKDDHKIYVYQ
                     LNQGVSQEKAETVSKEKGAGEIDKIIFGRYQDKPIWEVKSGSDFYLVDFETGALVNKE
                     GL"
     gene            53483..54670
                     /locus_tag="ACL3EZ_000591"
     CDS             53483..54670
                     /locus_tag="ACL3EZ_000591"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008483 - transaminase activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HGR0392211.1"
                     /translation="MKLSNRVLEMEESVTLAAGARAKALKAEGRDILSLTLGEPDFTT
                     PKNIQDAAIASIRDGRASFYTVTSGLPELKAAVNSYFERFYGYSVASNQVTVAAGAKY
                     SLYTFFMAVVNPGDEVIIPTPYWVSYGDQVKMAEGVPVFVSAKEDNHFKVTVEQLEAA
                     RTDKTKVLVLNSPSNPTGMIYTREELLAIGNWAVENDILILADDIYGRLVYNGHEFTP
                     ISSLSEAIRKQTVVINGVSKTYAMTGWRIGYAVGEADIIAAMSKIAGQTTSNPSAVAQ
                     YAAVEALSGEQDTVESMRQAFEERLNTIYPLLAEVPGFEVVKPQGAFYLFPNVKKAME
                     MKGYTDVTDFTTAILEEAEVALVTGAGFGAPENVRLSYATDLDTLKEAVERLKAFMGS
                     END"
     gene            54663..55028
                     /locus_tag="ACL3EZ_000592"
                     /pseudo
     CDS             54663..55028
                     /locus_tag="ACL3EZ_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863759.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
     gene            55044..56390
                     /gene="asnS"
                     /locus_tag="ACL3EZ_000593"
     CDS             55044..56390
                     /gene="asnS"
                     /locus_tag="ACL3EZ_000593"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004816 - asparagine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006421 - asparaginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HGR0392212.1"
                     /translation="MMTKRVTIIDVKDYVGQEVTIGAWVANKSGKGKIAFLQLRDGTA
                     FFQGVAFKPNFVEKFGEEVGLEKFDVIKRLSQETSVYVTGIVKEDERSKFGYELDITD
                     IEVIGESQDYPITPKEHGTDFLMDNRHLWLRSRKQVAVLQIRNAIIYATYEFFDKNGF
                     MKFDSPILSGNAAEDSTELFETDYFGTPAYLSQSGQLYLEAGAMALGRVFDFGPVFRA
                     EKSKTRRHLTEFWMMDAEYSYLTHDESLDLQEAYVKALLQGVLDRAPQALETLERDTE
                     LLKRYIAEPFKRITYDQAIDLLQEHENDEDADYEHLEHGDDFGSPHETWISNHFGVPT
                     FVMNYPVAIKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSMREEDYDALVAKMDEL
                     GMDRTEYEFYLDLRKYGTVPHGGFGIGIERMVTFAAGTKHIREAIPFPRMLHRIKP"
     gene            56543..56833
                     /gene="rpsF"
                     /locus_tag="ACL3EZ_000594"
     CDS             56543..56833
                     /gene="rpsF"
                     /locus_tag="ACL3EZ_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HGR0392213.1"
                     /translation="MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATVVESKTWE
                     KRRLAYEIQDFREGLYHIVNVEANDDAALKEFDRLSKINADILRHMIVKIDA"
     gene            56845..57315
                     /gene="ssbA"
                     /locus_tag="ACL3EZ_000595"
     CDS             56845..57315
                     /gene="ssbA"
                     /locus_tag="ACL3EZ_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein SsbA"
                     /protein_id="HGR0392214.1"
                     /translation="MINNVVLVGRMTRDAELRYTPSNVAVATFTLAVNRTFKSQNGER
                     EADFINVVMWRQQAENLANWAKKGSLIGVTGRIQTRSYDNQQGQRVYVTEVVAENFQM
                     LESRSVREGHTGGAYSAPTANYSAPTNSVLDFSRNENPFGATNPLDISDDDLPF"
     gene            57347..57586
                     /gene="rpsR"
                     /locus_tag="ACL3EZ_000596"
     CDS             57347..57586
                     /gene="rpsR"
                     /locus_tag="ACL3EZ_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HGR0392215.1"
                     /translation="MAQQRRGGFKRRKKVDYIAANKIEYVDYKDTELLSRFVSERGKI
                     LPRRVTGTSAKNQRKVTTAIKRARVMALMPFVNED"
     gene            57881..59281
                     /locus_tag="ACL3EZ_000597"
     CDS             57881..59281
                     /locus_tag="ACL3EZ_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional Cof-type HAD-IIB family
                     hydrolase/peptidylprolyl isomerase"
                     /protein_id="HGR0392216.1"
                     /translation="MDAKLRYKAKKIKIVFFDIDDTLRNSKTGFIPTTIPTVFKQLRE
                     KGILTGIASGRGIFGVVPEIRDLKPDFFVTLNGAYIEDKKGQVIYQHQIEKSDVEEYI
                     SWAKQEGIEYGLVGSHDAKLSTRTDMMSEAINPIYPDLDVDPDFHEKEDIYQMWTFED
                     KGDDLHLPDSLSDKLRMVRWHQHSSDIVPISGSKATGVEKVVEHLGLKPEKVMVFGDG
                     LNDLELFDYAGISVAMGISHDKIKEKADYITKTLEEDGIFDALEVFGMVEKELHFPQV
                     DIETVEGPLATIKTNHGDLRIKLFPEHAPKTVANFVSLSKDGYYDGVIFHRIIKDFMI
                     QGGNPTGTGMGGESIYGESFEDEFSEELYNIRGALSMANAGPNTNGSQFFIVQNQHLP
                     YSKKEITRGGWPEPIAEIYANQGGTPHLDRRHTVFGQLADEASYAVLDAIAAVETGAM
                     DKPVEDVVIETIEIED"
     gene            59283..59642
                     /locus_tag="ACL3EZ_000598"
     CDS             59283..59642
                     /locus_tag="ACL3EZ_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HGR0392217.1"
                     /translation="MKIGDKLKGRITGIQPYGAFVELETGDTGLIHISEIRTGFIENI
                     HETLKVDEEVQVQVVDLDEFTGKASLSIRTLEEEKYQFPRRRRFSSDRFNYGFAPFRR
                     MLPIWTGEALHHLKKKK"
     gene            59696..60445
                     /locus_tag="ACL3EZ_000599"
     CDS             59696..60445
                     /locus_tag="ACL3EZ_000599"
                     /EC_number="2.1.1.223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008170 - N-methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016430 - tRNA
                     (adenine-N6)-methyltransferase activity [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HGR0392218.1"
                     /translation="MEEEQLLKSGERINQLFSTDIKIIQNREVFSYSVDSVLLSRFPR
                     FPKKGLIVDFCAGNGAVGLFASTRTQAQILSVEIQERLADMAERSVRLNGLEEQMQVI
                     CDDLKNMPAHIQGSKVDMILCNPPYFKVDPYSNLNESEHYLLARHEITTNLEEICHSA
                     QSILKSNGRLAMVHRPDRLLDILDTLKRHNLAPKRLQFVYPKREKEANMLLIEAIKDG
                     STSGFKVLPPLIVHNDDGSYTPEIEEIYYGS"
     gene            60435..60734
                     /locus_tag="ACL3EZ_000600"
     CDS             60435..60734
                     /locus_tag="ACL3EZ_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HGR0392219.1"
                     /translation="MDHKAYMYVLECRDGSYYIGYTTDMRRRLAIHNSGKGAKYTRAR
                     LPVKLIYAQGFVSKEEAMSAEALLKRKKRPQKEEFLSENQDRNLLSYFEESWGVL"
     gene            60805..61740
                     /locus_tag="ACL3EZ_000601"
     CDS             60805..61740
                     /locus_tag="ACL3EZ_000601"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004427 - inorganic diphosphate
                     phosphatase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HGR0392220.1"
                     /translation="MSKILVFGHQNPDSDAIGSSVAFAYLAKEAYGLDTEAVALGTPN
                     EETAFVLNYFGVEAPRVITSAKAEGAEQVILTDHNEFQQSVSDIAEVEVYGVVDHHRV
                     ANFETASPLYMRLEPVGSASSIVYRMFKEHGVAVPKEIAGLMLSGLISDTLLLKSPTT
                     HPTDKIIAPELAELAGVNLEEYGLAMLKAGTNLASKSAEELIDIDAKTFELNGNNVRV
                     AQVNTVDIAEVLERQAEIEAAMQAANESNGYSDFVLMITDIVNSNSEILALGANMDKV
                     EAAFNFKLENNHAFLAGAVSRKKQVVPQLTESFNA"
     gene            61827..62339
                     /locus_tag="ACL3EZ_000602"
     CDS             61827..62339
                     /locus_tag="ACL3EZ_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000892254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YiiX/YebB-like N1pC/P60 family cysteine
                     hydrolase"
                     /protein_id="HGR0392221.1"
                     /translation="MLENGDLIFVRDGSDMGQAIQTSTGNYSHVAIYLDGMIYHASGQ
                     AGVVCQEPADFFESNHLYDLYVYPEMDIQSVKERACRHLGAPYNASFYPDAAGFYCSQ
                     YIAEILPIFETIPMKFGDEEQEISDFWREYYIELGLPVPLNQAGTNPSQLAASPLLQC
                     KERNLHDSDF"
     gene            62323..62972
                     /locus_tag="ACL3EZ_000603"
                     /pseudo
     CDS             62323..62972
                     /locus_tag="ACL3EZ_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000614493.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
     gene            63073..63255
                     /locus_tag="ACL3EZ_000604"
     CDS             63073..63255
                     /locus_tag="ACL3EZ_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HGR0392222.1"
                     /translation="MSLENKLEQATGAVKEGFGKVTGDSKTELEGAVEKTVAKAKDVV
                     EDAKGAVEGLKNVFTK"
     gene            complement(63301..64746)
                     /locus_tag="ACL3EZ_000605"
     CDS             complement(63301..64746)
                     /locus_tag="ACL3EZ_000605"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HGR0392223.1"
                     /translation="MIKIETVLDILKKDGLFREIIDQGHYHYNYSKVVFDSISYDSRK
                     VTEDTLFFAKGAAFKKEYLLSAITQGLAWYVAEKDYEVDIPVIIVNDIKKAMSLIAME
                     FYGNPQEKLKLLAFTGTKGKTTATYFAYNILSQGHRPAMLSTMNTTLDGETFFKSALT
                     TPESIDLFDMMNQAVQNDRTHLIMEVSSQSYLVKRVYGLTFDVGVFLNISPDHIGPIE
                     HPSFEDYFYHKRLLMENSRAVIINSDMDHFSVLKEQVEDQDHDFYGSQFDNQIENSKA
                     FSFSATGKLAGDYDIQLIGNFNQENAVAAGLACLRLGASLEDIKKGIAATRVPGRMEV
                     LTQKNGAKVFIDYAHNGDSLKKLINVVETHQTGKIALVLGSTGNKGESRRKDFGLLLN
                     QHPEIQVFLTADDPNYEDPMAIADEISSYINHPVEKIADRQEAIKAAMAITNHELDAV
                     IIAGKGVDCYQIIQGKKESYPGDTAVAENYL"
     gene            64852..66474
                     /locus_tag="ACL3EZ_000606"
     CDS             64852..66474
                     /locus_tag="ACL3EZ_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HGR0392224.1"
                     /translation="MSHENNHQQAQMLRGTAWLTASNFISRLLGAVYIIPWYIWMGAY
                     AAKANGLFTMGYNIYAWFLLVSTAGIPVAVAKQVAKYNTMREEEHSFALIRSFLGFMT
                     GLGLVFALVLYVFAPWLADLSGVGKDLIPIMQSLAWGVLIFPSMSVIRGFFQGMNNLK
                     PYAMSQIAEQVIRVIWMLLATFIIMKLGSGDYLAAVTQSTFAAFVGMVASFAVLIYFL
                     AQEGSLKRVFETGDKINSKRLLVDTIKEAIPFILTGSAIQLFQILDQLTFINSMSWFT
                     NYSNEDLVVMFSYFSANPNKITMILISVGVSIGSVGLPLLTENYVKGDLKAASRLVQD
                     SLTLLFMFLLPATVGVVMVGEPLYTVFYGKPDSLALGLFVFAVLQSIILGLYMVLSPM
                     LQAMFRNRKAVLYFIYGSIAKLVLQLPTIALFHSYGPLISTTIALIIPNVLMYRDICK
                     VTGVKRKVILKRTILISLLTLVMFLLIGTIQWLLGFFFQPSGRLWSFFYVALVGAMGG
                     GLYMVMSLRTYLLDKVIGKAQADRLRAKFKLS"
     gene            66677..68635
                     /locus_tag="ACL3EZ_000607"
     CDS             66677..68635
                     /locus_tag="ACL3EZ_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HGR0392225.1"
                     /translation="MKKSKSKYLTLAGLVLGTGVLLSACGNSSTASKTYNYVYSSDPS
                     SLNYLAENRAATSDIVANLVDGLLENDQYGNIIPSLAEDWTVSQDGLTYTYKLRKDAK
                     WFTSEGEEYAPVTAQDFVTGLQYAADKKSEALYLVQDSVAGLDDYITGKTSDFSTVGV
                     KALDDQTVQYTLVKPELYWNSKTLATILFPVNADFLKSKGDDFGKADPSSILYNGPFL
                     MKALVSKSAIEYKKNPNYWDAKNVFVDDVKLTYYDGSDQESLERNFTAGAYTTARLFP
                     NSSSYEGIKEKYKNNIIYSMQNSTSYFFNFNLDRKSYNYTSKTSDIEKKSTQEAVLNK
                     NFRQAINFAFDRTSYGAQSEGKEGATKILRNLVVPPNFVSIKGKDFGEVVASKMVNYG
                     KEWQGINFADGQDPYYNPEKAKAKFAEAKKELEAKGVQFPIHLDKTVEVTDKVGIQGV
                     SSIKQSIESVLGSDNVVIDIQQLTSDEFDSSGYFAQTAAQKDYDLYHGGWGPDYQDPS
                     TYLDIFNTNSGGVLQNLGLEPGEANDKAKEVGLDVYTQMLEEANKEQDPAKRYEKYAD
                     IQAWLIDSSLVLPSVSRGGTPSLRRTVPFAAAYGLTGTKGVESYKYLKVQDKIVTTDE
                     YAKAREKWLKEKEESNKKAQEELAKHVK"
     gene            68807..69040
                     /locus_tag="ACL3EZ_000608"
     CDS             68807..69040
                     /locus_tag="ACL3EZ_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter"
                     /protein_id="HGR0392226.1"
                     /translation="MKLKLLRVDTKVIMGSFFLVLSSLLALLLPLILKGLIDGSSIEN
                     IGSKVFQSFLIFIGQALFSSIGYYLFSQSGEKR"
     gene            69058..69579
                     /locus_tag="ACL3EZ_000609"
                     /pseudo
     CDS             69058..69579
                     /locus_tag="ACL3EZ_000609"
                     /inference="COORDINATES: protein motif:HMM:NF012869.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter transmembrane domain-containing
                     protein"
     gene            69766..70488
                     /locus_tag="ACL3EZ_000610"
     CDS             69766..70488
                     /locus_tag="ACL3EZ_000610"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0392227.1"
                     /translation="MNFNHVYFGYDENRPVLKDIICSIFKGQKIAFVGPSGSGKSTIV
                     RLLERFYKPLSGDILMEQSSIYDFNLKEWRSKIAWVSQNNAVLSGSIRDNLCLGLNRL
                     VTDDELMKVLDLVSLGDEIRSMKEGLDTEVGERGRLLSGGQSQRLQIARAYLKDAEIL
                     IFDEATANLDADSEYAIISSLYSVLKEKTVVIIAHRLSTVKDVDCIFFLEEGKITGSG
                     THKELLENHERYARFVQEQMIE"
     gene            70646..71740
                     /locus_tag="ACL3EZ_000611"
     CDS             70646..71740
                     /locus_tag="ACL3EZ_000611"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HGR0392228.1"
                     /translation="MSKELHINTILAQAGIKSDEATGALVTPLHFSTTYQHPEFGRST
                     GFDYTRTKNPTRSKAEEVLAAIESADYALATSSGMSAIVLAFSVFPVGSKVLAVRDLY
                     GGSFRWFNQVEQEGHFHFTYANTEEELIAELEKDVDVLYIETPTNPLMLEFDIEKLAK
                     LAHAKGSKVVVDNTFYSPIYQRPIEDGADIVLHSATKYLAGHNDVLAGVVVTNSLELY
                     EKLFYNLNTTGAVLSPFDSYQLLRGLKTLSLRMERSTANAQEVVAFLKDSPAVKEVLY
                     TGRGGMISFKVADETRIPHILNSLKVFSFAESLGGVESLITYPTTQTHADIPAEVRHS
                     YGLTDDLLRLSIGIEDARDLIADLRQALEG"
     gene            71748..72914
                     /locus_tag="ACL3EZ_000612"
     CDS             71748..72914
                     /locus_tag="ACL3EZ_000612"
                     /EC_number="4.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0047804 - cysteine-S-conjugate beta-lyase
                     activity [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MalY/PatB family protein"
                     /protein_id="HGR0392229.1"
                     /translation="MGKYDFTSLPNRLGHHTYKWKETETDSEVLPAWIADMDFVVLPE
                     IRQAVQTYADQLVYGYTYASEDLIKEVQKWEATQYGYNFDKEALVFIEGVVPAISTAI
                     QTFTKEGEAVLINTPVYPPFARSVKLNNRRLITNSLVEKDSLFEIDFDQLEKDLVEEE
                     VKLYVLCNPHNPGGRVWEKEVLEKIGQLCQKHGVLLVSDEIHQDLTLFGHKHQSFNTI
                     NPAFKNFAIVLSSATKTFNIAGTKNSYAVIENPKLRLAFQKRLLANNQHEISGLGYLA
                     TEAAYRYGKDWLEELKQVFEDHINYVVDLFGKETKIKVMKPQGTYLIWLDFSAYDLTD
                     ETLQELLRNEAKVILNRGLDFGEEGSLHARINIAMPKSLLQEVCQRIVATFAKC"
     gene            73007..76105
                     /locus_tag="ACL3EZ_000613"
     CDS             73007..76105
                     /locus_tag="ACL3EZ_000613"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HGR0392230.1"
                     /translation="MAKLIPGKIRIEGVALYETGKVDIIKEKNNRLYARVAEEELRYS
                     LEDDLVFCACDFFQKRGYCVHLAALEHFLKNDERGQEILWSLEEGHEEKEAVETKVTL
                     GGKFLDRILSPKSECAYELSAVGQVEAGTNHILWTLRIGQINSQKYYVIRDIPLFLRI
                     VEQRKSYMIGKIYEESLSWEAFDDASQELLTFLHGLTEEGLVPDLFFQNQGRHLFFPL
                     TFFEQGVNLLMALPHFQFDHQVDSYQTLLFQDMHADANLFAFTVTEYSDYFEMEISES
                     PRVNVFYQGAVLFHKGQVYFLTDQQMRLLKEIKALPVDRQGKKYLQFDSSDRDKLASC
                     LTLFIQMGTVSAPERLQIKTFAPSFYFDREEDNRIRLEIQFDYGNRQVSSRQELEELP
                     FSSDADLEERIFQVCLAAGFEADFQSWRQALKAESVYHFFHDIIPVFEKLGHVDLSDK
                     LEELYSLASPQVQIASKGGLLEIQFDFQDIAQEEIDQAIQALVANQDFYIDSSNQVYF
                     FDEETKKIRQNLQELGQFELKDGTLQARKSLAYSLAHLFEGRDRVSFSQEFQNLAQDL
                     THPEDFPLQATQVKTDLRDYQEKGIGWLQMLHHYGFGGILADDMGLGKTLQTIAFLTS
                     QVTKESRVLILAPSGLIYNWADEFQKFAPQLDVAVVHGLKASREEILADNHQIYVTSY
                     ATFRQDSELYQGMAFDFLFLDEAQVMKNAQTKIAQTLRQFVVPSVFALSGTPIENHLG
                     ELWSIFQIVMPGLLPSKKEFMKLPAERVAQFIKPFVMRRKKEEVLTELPDLIEVIYKN
                     ELEDQQKAIYLAQLQQMRDHLAQVSEQEFQRSRVEILSGLMRLRQICDTPALFMEDYQ
                     GASGKLDSLRDLLVQVADGGHRVLIFSQFKGMLEKIEQELPDLGLTSFKITGSTPAKE
                     RQDMTKAFNQGERDAFLISLKAGGVGLNLTGADTVILVDLWWNPAVEAQAIGRAHRMG
                     QEETVEVYRLVTKGTIEEKIQELQEQKKHLVSQVLDGTESRGSLTLAEIREILGISEA
                     ST"
     gene            76153..76770
                     /locus_tag="ACL3EZ_000614"
     CDS             76153..76770
                     /locus_tag="ACL3EZ_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HGR0392231.1"
                     /translation="MKQERFPLVSDDEVMLTEMPVMNLYDESDLISNIKGEYRDKNYL
                     EWAPIAEEKPVKPIEKQVGKPKKAPLGVKKEGKSYAEVAREEARADLKKKRSANYLTQ
                     DFSLARRHSQPSLVRQGNQPTTPFQKENPGEFVKYSQKLTQSHYILAEEVHSIPTKNE
                     EVSAPAPKKNNYDFLKKSQIYNKKSKQTEQERRVAQELNLTRMTE"
     gene            76781..78115
                     /gene="murC"
                     /locus_tag="ACL3EZ_000615"
     CDS             76781..78115
                     /gene="murC"
                     /locus_tag="ACL3EZ_000615"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008763 - UDP-N-acetylmuramate-L-alanine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HGR0392232.1"
                     /translation="MSKTYHFIGIKGSGMSALALMLYQMGHKVQGSDVEKYYFTQRGL
                     EQAGITILPFDEKNLDGDMEIIAGNAFRPDNNVEIAYADQNGISYKRYHEFLGSFMRD
                     FVSMGVAGAHGKTSTTGMLSHVLSHITDTSFLIGDGTGRGSANAKYFVFESDEYERHF
                     MPYHPEYSIITNIDFDHPDYFTSLEDVFNAFNDYAKQITKGLFVYGEDAELRKITSDA
                     PIYYYGFEAEGNDFVASDLLRSTTGSTFTVHFRGQNLGQFHIPTFGRHNIMNATAVIG
                     LLYTAGFDLNLVREHLKTFSGVKRRFTEKIVNDTVIIDDFAHHPTEIIATLDAARQKY
                     PSKEIVAVFQPHTFTRTIALLDDFAHALNQADAVYLAQIYGSAREVDHGDVKVEDLAN
                     KINKKHQVITVENVSPLLDHDNAVYVFMGAGDIQTYEYSFERLLSNLTSNVQ"
     gene            78125..78589
                     /locus_tag="ACL3EZ_000616"
     CDS             78125..78589
                     /locus_tag="ACL3EZ_000616"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR0392233.1"
                     /translation="MEIPIKIIQASKSDLPEIGALQTSSFPAEKQQLSHILEESIRKC
                     ADTFLLARDENQLLGYILSSPQSDNPQYLKVHSLVIESDHQRQGLGTLLLAALKEVAV
                     ELDYKGIRLESPDELLSYFEMNGFVDEEATLLYATSQGYSMIWFNPFYLEEQ"
     gene            78586..79080
                     /locus_tag="ACL3EZ_000617"
     CDS             78586..79080
                     /locus_tag="ACL3EZ_000617"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000702438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR0392234.1"
                     /translation="MKIRQARLEDLDRIVELEFENFSVEEAIPPSVFEAHLREIQTSF
                     LVAEKEGRIMGYIEGPVGLHRHLQDQSFTEEIKDYSHEPGGYISVTCLSIAKEAQGLG
                     LGQKLLTALKEVALEDERDGINLTCHDYLIAYYEKHGFVNEGQSQSTFAGETWYDMVW
                     EMKK"
     gene            79161..80816
                     /gene="mltG"
                     /locus_tag="ACL3EZ_000618"
     CDS             79161..80816
                     /gene="mltG"
                     /locus_tag="ACL3EZ_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008932 - lytic endotransglycosylase
                     activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HGR0392235.1"
                     /translation="MSEKSREEEKLSFKEQILRDLEKVKGYDEVLKEDEAVVRTPANE
                     PSTEELMADSLSTVEEIMRKAPTVPTHPSQGVPASPADEIQRETPGVPSHPSQDVPSS
                     PAEESGSRPGPGPVRPKKLEREYNETPTRVAVSYTTAEKKAEQAGPETPTPATETVDI
                     IRDTSRRSRREGAKPVKPKKEKKSHVKAFVISFLVFLALLSAGGYFGYQYVLDSLLPI
                     DANSKKYVTVGIPEGSNVQEIGTTLEKAGLVKHGLIFSFYAKYKNYTDLKAGYYNLQK
                     SMSTEDLLKELQKGGTDEPQEPVLATLTIPEGYTLDQIAQAVGQLQGDFKESLTAETF
                     LAKVQDETFISQAVAKYPTLLESLPVKDSGARYRLEGYLFPATYSIKESTTIESLIDE
                     MLAAMDKNLSPYYSTIKSKNLTVNELLTIASLVEKEGAKTEDRKLIAGVFYNRLNRDM
                     PLQSNIAILYAQGKLGQNISLAEDVAIDTNIDSPYNVYKNVGLMPGPVDSPSLDAIES
                     SINQTKSDNLYFVADVTEGKVYYANNQEDHDRNVAEHVNSKLN"
     gene            80887..81369
                     /gene="greA"
                     /locus_tag="ACL3EZ_000619"
     CDS             80887..81369
                     /gene="greA"
                     /locus_tag="ACL3EZ_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HGR0392236.1"
                     /translation="MAEKTYPMTLEEKEKLEKELEELKLVRRPEVVERIKIARSYGDL
                     SENSEYEAAKDEQAFVEGQISSLETKIRYAEIVNSDAVAQDEVAIGKTVTIQEIGEDE
                     EEVYIIVGSAGADAFAGKVSNESPIGQALIGKKTGDTATIETPVGSYDVKILKVEKTA
                     "
BASE COUNT        24826 a        15101 c        18425 g        23177 t
ORIGIN      
        1 caagagggag agtacctaaa atgggacgta agccaaaaaa gagacctgaa gagaggacag
       61 aattagaacg tcttcaagca gaaaatgagt acctgagagc ggagaatgcc atcctaaaaa
      121 agttaagaga actccgattg aaggaggaaa aagagaaaga cagaaattgt ttaagaatta
      181 atgactgagt tttcgttaga tcttcttcta aaagccatta aactagctcg ttcgacctac
      241 tactatcact tgaaacagct agacaaaaca gataaggacc aagagcttaa agctgaaatt
      301 caatccattt ttatcgaaca caagggaaat tatgcttatc gtcgaattca tttagaacta
      361 agaaatcgtg gttatctggt aaatcataaa agagttcaag gcttgatgaa agtactcaat
      421 ttacaagcta aaatgcgaca gaaacgaaaa tattcttctc ataaaggaga cgttggtaag
      481 aaagcagaga atctcattca aggccaattt gaaggctcta aaacaatgga acagtgctac
      541 acagatgtga ctgaatttgc cattccagca agtactcaaa agctttactt atcaccagtt
      601 ttagatggct ttaatagcga aattatcgcc tataatcttt caacttcacc caacttagaa
      661 caagtacaaa caatgttgga acaggcattc acagagaagc actacgagaa tacgattctc
      721 catagtgacc aaggctggca atatcaacac gattcttatc atcagtttct tgagggtaag
      781 ggaattcaag catccatgtc acgcaaggga aacagccaag acaacggtat gatggagtcc
      841 ttctttggga ttctgaaatc ggaaatgttt tacggttatg agaagtcgtt tcagtcgctt
      901 aagcaattgg aacaagctat tgtagactat attgattact acaacaataa acgaattaag
      961 gtaaaactaa aaggacttag tcctgtgcaa tacagaacta aatccttcgg ataaattatt
     1021 tgtctaactg tttgggggca gtacatttta acacttgata ctatgcgttt tattgtggga
     1081 agattttcct cattttctag tgaaattgaa ctttttctaa catcttttga tagatgactt
     1141 cttaatcaat tatcatttcc attgttgttt cttggggttt catcccttgt ctttgataaa
     1201 agcggagagc accctcgtta tcattccaga cacttagggt tagattattg cagccaattt
     1261 ctttagcata atagcagaaa aatgacaata aaatagcccc tagatatttt gaaaggaaag
     1321 cataggggct atatagttta atcaaaataa agcaaatctt tgctggtgct tgtaaagagg
     1381 tcgaagccat ccttggtaac aacaccgcag tcttcaatac gaacaccgac tttaccaggg
     1441 atatagatac ctggttcaac agagaagcac atgccttctt cgatgaccat gtcgtttcct
     1501 tccatgatag atgggaattc atggacatcc ataccgatac catgcccgag acggtggttg
     1561 aagtactcac cataaccagc tttttcgatg acctcacggg cagcgcggtc cacttcatga
     1621 gcagtcacac ctggcttgat aaagtcaaga gcagcttgtt gggcttcaag agtcaagttg
     1681 taaatatctt tcttgaattg gtctggtttg ccgacagcga ctgtacgagt catatctgac
     1741 gcatagccat tgaccagaac acccaggtca aagaggagaa gagcatcatt ttcaacctta
     1801 ttagctgctg gaatgccgtg tggattcgca gcattatcac cagtcaagac catggtatca
     1861 aagctcattt cataaccttc acgtttcatg gcaaagtcga tttgtgcgat gatatctgtc
     1921 tcagtcttat caagagaaat attgtcaaaa ccaacatgaa cagccttgtc agcataaaga
     1981 cctgcaacca tcattttttg cacttcatca gctgatttga tgaggcgcat gcgttggata
     2041 cgaggagtga ggttgtcaaa ctcagcagtc tcaaaaactg ttttcaaacc atggtatttg
     2101 gtcaagatga gattgtcaaa ctcaacagcg acacgtttga agtcaagttg tggaagagca
     2161 tgtttgattt tttgccatgg attttcagaa tcgacatagc ccactactgg gaaggaaacg
     2221 gtgctacttg cacgttctac ttcaagagct gggacaaaga ggagaggttc ctgatccgct
     2281 aggacaaaga ggaacatttg gcgttcatgg ggatcactgt aaaaaccagt gaggtaattg
     2341 attgtgacgg ggtcagatac gacagcgacg tctagttttt ctgattcaag atatgttagg
     2401 atttgttgta atttagacat atgctacctt ctttctaccc ctctattttg gcaaaaaatg
     2461 agagaaaatg caagggagaa gggtaaaaga aaagacaaaa aactccgaca agataacgga
     2521 gttctttgat atcattttcc tttgtttaag aaaagtcagc cttgcttttg acgtcactgt
     2581 actcttcagc gatttcttgg ctgagaatgt cctcataggc agggagttgg atgtcctgac
     2641 catatttctt cttgagggca gtagtaacta ggcgataagc cagattggca ttacgagaga
     2701 ggataggccc gtggaagtag gaaccaaaga cattcttata atgaacccct tcaccgacct
     2761 tttcttcgtt gtttccattt ccatagacaa cctgtcccag cggtttttgg tcatcagaga
     2821 ggaaggtacg accttggtga ttttcaaatc catagtaggt ttcatcgaaa tcttcattgt
     2881 gaatcttgat gtcaccgata aaacggttat tggtctggtt gagcgtgtag tgtcccatga
     2941 cccctagccc ttcgatacgt tttcctgaag cttcaacata atattgaccc aatagttgga
     3001 aaccaccgca gatagccaga actacaccgt cgttttggat gtagttgtca atgctctctt
     3061 ttttagcagg taggtcgtct gcaatgatac tttgttcaaa gtcttgacca ccaccgaaaa
     3121 aggcgatgtc gtagtgattt tcatcaaagt catcatggag agaaacgatg tcaacggtca
     3181 catgggctcc cagtttttca gccacatact tgagcatgag gatgtttcca ttgtccccgt
     3241 aggtattcat gagatttccg tagaggtggg caatgttgag ctgatagggg taattgctat
     3301 cttttgagga aagtgaagta taaaccatta gttcatctcc tttctaacaa tctgacgact
     3361 agccagcagt tcacgaaatt ccagcatggc agtataagtt gccagaatat aggcatgctt
     3421 gcagtcttga ttctcaatgg tcttgagaac ttgctccaga ttactcgttt cagtgatttt
     3481 ctcagctgga tagccagtca ctcggaggcg acgagcgatt tcagaatgac gaacaccgcc
     3541 agcgttgatt tcaggaatgt ccatgtcagt gatttgctca aagtctgcat cccagatcca
     3601 gctagtgtca attccatctg catagttggc attaaggagg acagataggc taaatggata
     3661 aggtgctagt ttgatcattt cgatagcttg ggttgcaccg actggatttt taatcaagac
     3721 aagggtacat tccttgtcac cgatatgaaa ggtttcttgg cgtccaaaga cagcacggct
     3781 cttgtcaaat ccctgtttga tgagttggga atctgcgccg aggaaacggg cgatggccac
     3841 agcagctagg gcgttataga tattatagag cccgccgatt tggataccgt attcttggcc
     3901 gtctatgaca aagcgagagc gattgttggt caactcaacc agttttgtca aacgatagtc
     3961 gagatcagga cgtttacatc cacaaccttc acagatatag gcacccaagt ttgcataggt
     4021 attatgctca tatttgagga tgccttggca gtcaggacag agaatccctt cggtattgta
     4081 gtgagcaagt tgggctggtc ctttttccaa gtcaaaacca aaatactcta tagggtttgg
     4141 aatagttggc ttgtagaaaa gtggactgtc tccgttaagg agaacagtag cagttggaac
     4201 ttttcgaatg gcatccaata tcatgttata ggtagtatag atttcaccga aacggtccat
     4261 ctggtcacgg aagatattag taatgacaaa aagactaggc tggatatagt cacagatacg
     4321 agatagactg gcttcgtcaa tttcgaggac ggcaatattt ttcccagttt ttgaagattt
     4381 ggctgttagg aaggttgttg caatccctgt aatcatgttg gcaccgcttg ggttggttag
     4441 aacttgacca taaacctctt ttaaaatgcc gacagtgagg gcagttgtca gggtttttcc
     4501 atttgttcca gtgacaacga caatctcgta gttcttagct aggctttgta aaatatcttt
     4561 atcaaattga agggcgactt tccctgggag cgtacttcca cgtccaagac ggcttaaaac
     4621 gaagtgggaa gaacgcccag caagaaggcc caaagtagtt tttaagttca tgtttctatt
     4681 atatcacaaa agagggaaaa gacagatttg gtgtttcgta gaagtaaaaa cagcccaaag
     4741 agggctgtca gttaagatga gatttcaact taaatcgcaa acaagtcatt caagttctca
     4801 gccaaggttg ggtgagtgaa gatttgtttt gtgaagtaag tgtaaggaat cttgttgtcc
     4861 atagcaacag taatgatgtt gatgatttct tgagaacctt ctgagaagat gcttgcacca
     4921 agaatttctt ttgtttcagt attaacaaca gctttgaaag ctccgcgaag gtctccattt
     4981 acgtgaccac gaggcatggc tgcaacaggg atttctttca ctgcgtatgg aagtttcaaa
     5041 tcagctgctt ggctttcagt caaaccaact tgtgaaagtg caggtgtgat gaacatagta
     5101 tttggcacat tgagacggtc ctcaagtgtg tagctgccat ctccagcaag gtagctgtaa
     5161 acaacacgga agtcatcaag tgaaatgtaa gtaaattgaa ggccaccgtt gacatctcca
     5221 actgcaaaga caccaggaac gtttgtttga cagtgtttgt ctactttaat agcaccacgt
     5281 tcagttagtt caatatctgt attttcaagt tgaagtggtt ctacatttgg tttgcgtcca
     5341 gttgcgtaga gaagggcgtc gaaacggtaa gtttcgtctt cagttacgac aagcacttgg
     5401 tcaccatcgt ttttgatttc agtagtatgg atattttgaa gcaattcaat gccatcttct
     5461 tccatgtatt gtttagcaag agctgcgatg gaaggttctg cacgaggtag gaatgtatcc
     5521 aaggcatcta ggactgtgac cttgcttcca agtttgttgt aaaggccggc aaattcaaga
     5581 ccgatatttc cgccaccaag gattccaagt ttttcaggta atttgtccaa gctttggata
     5641 cctgttgagt caaagatgtt tttgcttgta gcaagtccag gaattggcaa gacgtttgaa
     5701 acagcaccag tgttgatgac gattgtttca gcagtcagtt ctttcttttc atcaccagct
     5761 tggatttcga tgactttatt tgaaaggaag tgagcttccg catcaaagat atctacgcct
     5821 gtaccagcaa cagtcgcata gtttttaccg ttgaggcgac cagtgatcgt gtttttagta
     5881 gcaatcactt cttcaaaaga caagtccttt tcagcagcaa ctagcaaggt tttagttggg
     5941 atacaaccaa tgttgataca agttccaccg tacatagcct tgctgcgttc aacgagggca
     6001 acttttttgc cagctgaagc caatttacct gctagtgttt taccagcttt accaaatcca
     6061 ataacaatta aatcgtatgt taacatttat cttcctccta ttcgaatttc attctagcac
     6121 aagaaaaaaa cttttgcaca attctgctac ggaaaagaca gaaaaagata aaaacgcttt
     6181 ccagacaaaa aactagtaat tttttgacaa gcttgataaa ctaaaatcct atctattttt
     6241 atataagaaa gaataaatgt tcgaaaatag gaggttttat gaaatcgaat cgttatatta
     6301 ttgcctttgc tggggtcatt ttacacttaa tgctgggttc gacttatgct tggagtgttt
     6361 atcgtaaccc tattattgaa aaaacgggat gggatcaggc ttctgttgcc ttcgccttta
     6421 gtctagcaat cttttgtttg ggcttatcgg ctgcatttat ggggcgtttg gtagaaaaat
     6481 ttggtccgaa agtcatgggg agtctatctg cttttctata cgcaggtgga aatatcttaa
     6541 caggatttgc aatagaccgt caggaactgt ggttgttgta tctagcttat ggcattttag
     6601 gtgggcttgg tttgggagca ggctatatta cccctgtgtc aacgattata aaatggtttc
     6661 ctgataaacg tggtctcgca acaggtttag cgattatggg gtttggtttt gcttctttat
     6721 tgactagtcc catagcgcaa cacctcatcg caggggtagg gattgtagaa actttttata
     6781 ttttaggagc aagttacttt attatcatgc tcctagcttc acaattcatt aagcgtccaa
     6841 atgagcaaga gcttgcaatt ttatcttctt cagggaaaga aaaaacagcc tctttgacgc
     6901 aaggaatggc tgcaaatcag gctctaaaaa gcaatcggtt ttatatgctt tggattattt
     6961 tctttatcaa catagcttgt ggtttaggct taatttcagc ggcatcgcca atggcacagg
     7021 agatggctgg cttgtctaca agtcatgcag cagtaatggt gggtgttttg gggattttca
     7081 atggatttgg tcgcttgctc tgggcgagtt tgtctgacta tatcggtcgc cctctaacct
     7141 ttagtatatt actgcttgtc aatcttttct tttctctctc actttggctc tttacagatt
     7201 ccgttttatt tgtagttgct atgtctattt tgatgacttg ctatggagct ggtttttctt
     7261 tgattccagc ttatctcagt gatatttttg gaaccaagga attggccgct ctgcatggtt
     7321 atattttaac agcttgggca atggctggtt tagcgggacc tattttatta gcagagactt
     7381 ataaaatggc tcattcgtac acacaaacct tgttcgtttt tctcatttta tacagtatcg
     7441 ccttggcttt gtcttattat ctaggtcgtt caatcaaaaa agaaagtcaa aaaccgctta
     7501 catgattttc tgtagaaatg gggctatctt ttgctctggt cttgtgttat actagatagg
     7561 ttgcaaagaa aacagtactt ttcttttgtg gaaaagaagc aacacgattt tatatctagt
     7621 tatatgaaaa tacgtcataa aaagaaaagt ataaactaag ccctataggg tggcttcgca
     7681 ccacctttag aaagaagaat aacgtgaaat ttaatgaatt aaacttgtct gctgatttgc
     7741 tagcagaaat tgaaaaagct ggttttgtag aagctagtcc tatccaagaa caaactattc
     7801 ctttggccct tgaaggcaag gatgttatcg gtcaagctca gactggtaca ggaaaaactg
     7861 cagcctttgg cttgcctacc cttgaaaaaa tccgtataga agaagcgact attcaagcct
     7921 tggtcatcgc tccaactcgt gaactagctg tccaaagtca agaagaactc ttccgctttg
     7981 gtcgtagtaa gggagtcaaa gtccgttcag tatatggcgg atcaagcatt gaaaaacaaa
     8041 ttaaggctct taaatctggt gcccatatcg tggtgggaac tccaggtcgc ctcttggact
     8101 tgattaaacg caaggccttg aaattacaag acattgaaac ccttatcctt gacgaagcgg
     8161 atgaaatgct taacatgggc ttccttgaag acatcgaagc cattatttcc cgtgtacctg
     8221 agaaccgtca aactttgctt ttctcagcaa ctatgccaga tgccatcaaa cgtatcggtg
     8281 ttcagtttat gaaagcccct gaacatgtca agattgcggc taaggaattg acaacagaat
     8341 tggttgacca gtactatatc cgtgttaagg aacaagaaaa atttgacacc atgactcgtc
     8401 tcatggatgt ggcacaacca gaactcgcta ttgtatttgg tcgtaccaaa cgccgtgtgg
     8461 atgaattgac tcgtggtttg aaaattcgtg gcttccgtgc agaaggaatt catggcgacc
     8521 tagaccaaaa caaacgtctt cgtgtccttc gtgactttaa aaatggcaat cttgatgttt
     8581 tggttgcgac agacgttgca gcgcgtggtt tggatatttc aggtgtgacc catgtctaca
     8641 actacgatat tccacaagat cctgagagtt atgttcaccg tatcggtcgt acaggtcgtg
     8701 ctggtaagtc aggtcaatct attacttttg ttgctccaaa cgaaatgggt taccttcaaa
     8761 tcattgaaaa cttgactaag aaacgcatga aaggtctcaa acctgcaagt gtagaagaat
     8821 ccttccaatc aaaaaaacag gtagctctca agaaaatcga acgtgatttt gcagatgaaa
     8881 ccattcgtgc caactttgag aaatttggta aggatgctcg caaattggct gctgagttta
     8941 ctccagaaga attggcaatg tatatcttga gtctgacagt ccaagaccca gatagccttc
     9001 cagaagtgga gattgcacgt gaaaaaccac taccgtttaa accatcaggt aatggtttcg
     9061 gtggtaaagc taagggaggt cgtggaggcc gtcgtgggga cgaccgtcga gagcgtgatc
     9121 gtcgtggcaa tggtcgccgt gatgagttca aaaaaggaag tcgtggcaac gatcgttttg
     9181 ataaggaaaa acgttaccgt aaggataata aaaaaccacg caatacttta agcgaaaagc
     9241 aaacaggctt tgttattcgt aacaaaggtg ataaataaga aaaagcggtt caaaatgaat
     9301 cgctttttta tataaggaga ccgaatgtga aaaagacaaa taaaattatt atattatctt
     9361 ttataatatt atgatacaca aaaataggcg acttgtcaat agaaaaggaa caatttaatt
     9421 aaaaatattc tggtttttaa ttaaattgta agtcaatgca agtcaataag gaattttcag
     9481 ataattattg aaaaagagac gtttttatgt tataatgata gcgattaaat tcgaggtgaa
     9541 aaatggcaca tttattagaa aaaactagaa aaattacatc aattttgaaa cgctcagagg
     9601 agcagttgca ggatgagctc ccttacaacg ctattacgcg tcagttagcg gatattattc
     9661 attgcaatgc ctgcattatc aatagtaagg gacgtctgct tggctatttt atgcgttata
     9721 aaacaaatac agatcgcgta gagcaattct tccaaactaa gattttccca gatgactacg
     9781 ttcaaggggc taatatgatt tacgaaacag aagcaaactt gcctgttgag catgatatga
     9841 gtattttccc tgttgagagt agagatgatt ttccagatgg cttgacgact attgcaccga
     9901 ttcatgtatc ggggattcgc cttggttctt tgattatttg gcgtaatgat aaaaaattcg
     9961 aagatgagga cttggttctt gttgagattg ccagtaccgt tgttgggatt cagcttctta
    10021 acttccaacg tgaagaagat gagaaaaata ttcgtcgtcg tactgctgtc accatggcgg
    10081 tcaataccct ttcttactcc gaactccgtg ctgtttcagc aattttaggg gaattaaatg
    10141 gaaatgaagg gaagttgact gcgtcagtga ttgcagatcg tatcggaatc actcgctctg
    10201 tgattgtcaa tgctcttcgt aaacttgagt ctgcggggat tattgaaagt cgctcacttg
    10261 gaatgaaggg aacctatctt aaggtcttga tttcagatat ttttgaagaa gtgaagaaaa
    10321 gagattacta atgacaaagg ctttaatttc gattgattat acagaagatt ttgttgctga
    10381 tagtgggaag ctgacagcag gtgctccagc tcaggcgatt tcggatgcca tcagcaaggt
    10441 aactcgatta gcttttgaac gaggagatta tatcttcttt actattgatg ctcatgaaga
    10501 aaacgattgt ttccatccgg aaagtaagtt atttcctcct cataatctga ttgggacgag
    10561 tggacggaat ttatatggag atttggggat cttttatcaa gagcatggtt cagacagtcg
    10621 tgtcttttgg atggataaac gccattactc agctttttca gggactgacc tagatattcg
    10681 tttgagagag cgtagagtgt ctaccgttat cttaacaggt gtcttgacgg atatctgtgt
    10741 cctacataca gctatagatg cctataatct aggatatgac atcgagattg ttaaaccagc
    10801 tgttgcttcc atctggcctg aaaatcatca atttgcccta ggtcatttca aaaatacact
    10861 cggagctaag ttagtagatg aaaatctaaa tgaactttct gagtaacctg gttggtgaaa
    10921 atgaaaaaat ttgaaaaaaa gtgttgacaa gcatcccaaa agttgatata ctagtaaagt
    10981 aatcgatgcg gggatggcgg aattggcaga cgcgcaggac taaggatcct gtgaccgctt
    11041 taggtcgtga gggttcaagt ccctctctcc gcataggaaa agagttagct aaagctagct
    11101 cttttgtatt tctctaaaaa attagaatcc agtcaaatgt agtggagaat cagcgaaaat
    11161 atgggaaaac tgatccttgt ttctgctttt gtcatagaag aataataaag attatcttct
    11221 tcaaattctc cgatattctc taaagttttg tgcaagttgc acagaacttt tttatttttt
    11281 tggtcatctt gccatagaaa tataaagcgt tttcatctat aatataatta tcaaaagaca
    11341 aaaggagttc acctcatggt agaattgaat cttaaaaata tttacaaaaa atatccaaac
    11401 agcgaacact attcagttga agatttcaac ttgaacatca aagataaaga atttatcgtt
    11461 ttcgtaggac cttcaggatg tggtaaatca actacactcc gtatgattgc tggtcttgaa
    11521 gacatcacag aaggtactgc atctatcgat ggcgtggttg tcaacgacgt agctccaaaa
    11581 gaccgtgata tcgccatggt attccaaaac tacgctcttt acccacacat gactgtttat
    11641 gacaacatgg ctttcggttt gaaattgcgt aaatacagca aagaagacat taacaaacgt
    11701 gttcaagaag cagctgaaat acttggattg aaagaattct tggaacgtaa accggctgac
    11761 ctttcaggtg gtcaacgtca acgtgttgcc atggggcgtg cgattgtccg tgatgcgaaa
    11821 gtattcttga tggacgaacc tttgtcaaac ttggatgcca aacttcgtgt atcaatgcgt
    11881 gctgaaatcg ctaaaattca ccgtcgtatc ggagctacaa ctatctatgt aactcacgac
    11941 caaacagaag cgatgacact tgcagaccgt atcgttatta tgtcagctac taagaaccct
    12001 gctggtacag gtactatcgg acgtgtagaa caaatcggta ctcctcaaga agtttacaaa
    12061 aatccagtta acaaattcgt tgcaggattc atcggaagcc cagctatgaa cttcatcaac
    12121 gtgaaattgg ttggtagcga aattgtttct gacggtttcc gtttgaaagt gccagaagga
    12181 gcattgaaag ttcttcgtga aaaaggctac gaaggaaaag aattgatctt tggtatccgt
    12241 ccagaagacg tgaatgcaga acctgctttc cttgaaacat tcccagactg tgttgtaaaa
    12301 gcgactatct ctgtatcaga actgcttggt tcagaatctc acctttactg ccaagttggt
    12361 aaagacgagt ttgttgcaaa agttgatgct cgtgactact tgcaaacagg tgcaacagtt
    12421 gagcttggat ttgacttgaa caaagcacac ttcttcgatg tagaaactga aaaaacaatc
    12481 tactaagaat aaataaaatt caaagcacta caagaaaaga tatctcttta tcaattgtag
    12541 tggagagata tcagttaatc tagggagaga aacaaaatgc ttctctcctt tttgctaggg
    12601 aagtcatatt atacatctat attgtgatgc tctttatact cttcgaaaat ctcttcaaac
    12661 cacgtcaacg tcgccttgcc gtacgtatga ttactgactt cgtcagtttt atctgcaacc
    12721 tcaaagctgt actttgagta gcttacggct agtttcctag tttgctcttt gatttccatt
    12781 gagtattatt tgtgggtacc atctacaagt gaagctatat gcgtaaacta cgtgagcaat
    12841 tgaattcgaa ctagagaggt aataataaat ttatgctata gttatggtga cttgtatgct
    12901 tttgattcta gtttatcaaa taatagatta gaattgtcag ataatatcat tttgtgtcat
    12961 tttgtgttat aatgaagaaa aaacagaggt gttcaaatgt cagagcaggt cataagtttt
    13021 tagcaaaatt ggggaaaaaa cgcttacgtc caggtggaaa gcgtgccaca gattggttaa
    13081 ttgcagaagg aggattttca aaagaaaaga gaatactaga ggttgcgtgt aataggggaa
    13141 ctacagcaat tgagttggca cagcgttttg gttgcaagat aactgctgtt gatatggatg
    13201 ctcaagcttt agaagtggct aaaaaatctg ctggaacggc aggtgttgct catttaatca
    13261 gttttgaaag agcaaatgca atgaaacttc cttatcaaga tgctagtttt gatattgtta
    13321 taaatgaagc tatgctgact atgcaagccg atcaagctaa gaaaaaatgt gtaatggaat
    13381 atctaagggt attaaaacct ggaggtcttc tcttgacaca tgatgtgctt cttaaggaag
    13441 ctaaagagtc tatcagacag gaattatcac aagcaattca tgtaaatgta ggtcctttaa
    13501 ctcaagatgg ttgggaacag gtgatgatag aatcaggtta ttgtgatgtg aaagtattga
    13561 ctggtgaaat gacattaatg aaattatcgg gtatgattta tgacgaaggt tggctaggaa
    13621 ctttgaaaat ttgtgtaaat gcttgtaaaa aggagaatag aaagcagttt ttaactatgt
    13681 ataaaatgtt tgctaagaat aaacagaaat tgggctttat tgcgatggct agttataaat
    13741 cgtcaaaacg ttagataatt attgaagtta acttttcctt ttttctttct taaaaaatat
    13801 gctataatag agagtaaaaa actttgaaag aaagaaaaag atgaatttaa aagattacat
    13861 tgcaacaatt gaaaattatc caaaggaagg cattaccttc cgtgatatta gtcctttgat
    13921 ggctgatgga aatgcttata gctacgctgt tcgtgaaatc gttcagtatg ctactgacaa
    13981 gaaagtcgac atgatcgtgg gacctgaagc tcgtggattt atcgtgggtt gtccagttgc
    14041 ctttgagttg ggaattggtt ttgcgcctgt tcgtaagcca ggtaaattgc cacgcgaagt
    14101 tatttctgct gactatgaaa aagagtacgg tgtcgatacc ttgactatgc acgcggatgc
    14161 cattaagcca ggtcaacgtg ttcttattgt agatgacctt ttggcgacag gtggaactgt
    14221 taaggcaact atcgagatga ttgaaaaact tggtggtgtt atggcaggtt gtgccttcct
    14281 tgttgaattg gatgaattga acggccgtga aaaaattggt gactacgatt acaaagttct
    14341 tatgcattat taatgaaaac agtccctagg gctgttttct ctacactagg atataaaaat
    14401 agactataac tagttagaga aaaactataa ttgaaaacta tatcttctta cagtataata
    14461 aaaggactaa gtgtttgaga tttgtcttca aacatatgca attattcctg aaagagtaca
    14521 gttaggagag ggttatgccg attcgaattg ataaaaaatt gccagctgtt gagattttac
    14581 ggacagagaa tatctttgtc atggatgatc aacgtgctgc ccaccaagat atccgtcctt
    14641 tgaagatttt aattttaaat ctcatgccac agaaaatggt cacagagacc cagttgttgc
    14701 gccacttggc taatacaccc ctacaactgg atattgattt tctctatatg gagagccacc
    14761 gttctaaaac aactcgttca gagcacatgg agaccttcta taaaactttt cctgaagtca
    14821 aggatgagta ttttgatggg atgatcatca cgggtgctcc agttgagcat ttaccatttg
    14881 aggaagtgga ctattgggag gaatttagac agatgcttga gtggtctaag actcatgtct
    14941 attcgaccct tcatatctgt tggggggctc aggctgggct ttatctgcgc tatggtgtag
    15001 aaaaatacca gatggacagt aagctatcag gtatttatcc tcaggacacc ctaaaagagg
    15061 gtcaccttct atttagaggc tttgatgata gctatgtatc ccctcattca cggcacacgg
    15121 agatttctaa ggaagaggtc ttaaacaaga ccaatctcga gattttatca gaaggacctc
    15181 aggttggggt ttctattttg gccagtcgtg atttacgaga aatttatagt tttggtcatt
    15241 tggagtatga ccgtgatacc ttggcaaaag agtattttcg agatcgtgat gcaggtttcg
    15301 acccacatat tccagaaaat tactttaaag atgatgatgt taatcaggta ccttgtcttt
    15361 gttggtcttc atctgcagcc ctctttttca gtaattgggt aaaccatgcg gtctatcagg
    15421 agacgccttt tgactggaga aagatagaag atgatgcatc tgcatatagg tatttataag
    15481 aggaattatg acatatttag acgcttttaa atcaggtacc ttggttttac cgagtgccct
    15541 gctcttgcat tttaaggaac tctttccttc tagcgacgat tttctggttt ggcaattttt
    15601 ctatttgcaa aatacgacag gcttagaaga aatatcgcca agccagattg ctgaaaggat
    15661 tggcaaggaa atttcggatg tcaaccagtc catttctaat ctgacggaaa ggggactgct
    15721 ccagtatcgt actatcgaat taaatggcga aattgaattg ctctttgatg ctagtttggc
    15781 cttggaacgt ttggatgacc tgtttggagc agttcattca agttcagacc agctaacacc
    15841 acaaaaccag ctcaaggatt tggtggaaac cttccagcag gagttgggac gattgttgac
    15901 gccttttgag attgaggatt tgaccaagac actaaaggaa gatggaacca gtgctgactt
    15961 gattaaggag gctcttcgtg aagctgtttt gaacggaaaa ccaaactgga agtacattca
    16021 ggcgattttg agaaactggc gccatgaagg aatcaagagt gtggctcaaa ttgaggccaa
    16081 gagagcagaa agagaagcaa gcaatcctca gttgacacag gtatctgcag atttcataaa
    16141 tgccatggat ctctggaagg attaatccat gcaagtaggc ttgaaatccg agtaagattt
    16201 gcaagctgtg tataattgtg atagaataaa tagaaaataa attgaaaaaa gaggtatgtg
    16261 aaatgtcacg taaaccattt atcgctggta actggaaaat gaacaaaaat ccagaagaag
    16321 ctaaagcatt cgttgaagca gttgcatcaa aacttccttc atcagatctt gttgaagcag
    16381 gtatcgctgc tccagctctt gatttgacaa ctgttcttgc tgttgcaaaa ggctcaaacc
    16441 ttaaagttgc tgctcaaaac tgctactttg aaaatgcagg tgctttcact ggtgaaacta
    16501 gcccacaagt tttgaaagaa atcggtactg actacgttgt tatcggtcac tcagaacgcc
    16561 gtgactactt ccatgaaact gatgaagata tcaacaaaaa agcaaaagca atctttgcga
    16621 acggtatgct tccaatcatc tgttgtggcg aatcacttga aacttacgaa gctggtaaag
    16681 ctgctgaatt cgtaggtgct caagtatctg ctgcattggc tggattgact gctgaacaag
    16741 ttgctgcctc agttatcgct tatgagccaa tctgggctat cggtactggt aaatcagctt
    16801 cacaagatga tgcacaaaaa atgtgtaaag ttgttcgtga cgttgtagct gctgactttg
    16861 gtcaagaagt cgcagacaaa gttcgtgttc aatacggtgg ttctgttaaa cctgaaaatg
    16921 ttgcttcata catggcttgc ccagacgttg acggtgccct tgtaggtggt gcgtcacttg
    16981 aagctgaaag cttcttggct ttgcttgact ttgtaaaata atcagtaagt agcaaaagct
    17041 aggtggaaca gcattcagat gtctgttaca ttttttatag gagaggaaag attgaaaaca
    17101 aaaattggat tagcaagtat ctgtttacta ggcttggcaa ctagtcatgt cgctgcaaat
    17161 gaaactgaag tagcaaaaac ttcgcaggat acaacgacag cttcaagtag ttcagagcaa
    17221 aatcagtctt ctaataaaac gcaaacgagc acagaagtac agactaatgc tgctgcccac
    17281 tggtatgggg attattatgt aaaggatgat ggctctaaag ctcaaagtga atggattttt
    17341 gacaactact ataaggcctg gttttatatt aattcagatg gtcgctactc gcagaatgaa
    17401 tggcatggaa attactacct gaaatcaggt ggatatatgg cccaaaacga gtggatctat
    17461 gacagtaatt acaagagttg gttttatctc aagtcagatg gggcttatgc tcatcaagaa
    17521 tggcaattga ttggaaataa gtggtactac ttcaagaagt ggggttacat ggctaaaagc
    17581 caatggcaag gaagttattt cttgaatggt caaggagcta tgatgcaaaa tgaatggctc
    17641 tatgatccag cctattctgc ttatttttat ctaaaatccg atggaactta tgctaaccaa
    17701 gagtggcaaa aagtgggcgg caaatggtac tatttcaaga agtggggcta tatggctcgg
    17761 aatgagtggc aaggcaacta ctatttgact ggaagtggtg ctatggcgac tgacgaagtg
    17821 attatggatg gtgctcgcta tatctttgcg gcctctggtg agctcaaaga aaagaaagat
    17881 ttgaatgtcg gctgggttca cagagatggt aaacgctatt tctttaataa tagagaagaa
    17941 caagtgggaa ccgaacatgc taagaaaatc attgatatta gtgagcacaa tggtcgtatc
    18001 aatgattgga aaaaggttat tgatgagaac gaggtggatg gtgtcattgt tcgtctaggt
    18061 tatagcggta aagaagacaa ggaattggcg cataacatta aggagttaaa ccgtctggga
    18121 attccttatg gtgtctatct ctatacctat gctgaaaatg agaccgatgc tgagaatgac
    18181 gctaaacaga ccattgaact tataaagaaa tacaatatga acctgtctta ccctatctat
    18241 tatgatgttg agaactggga atatgtaaat aagagcaaga gagctccaag tgatacagac
    18301 acttgggtta aaatcatcaa caagtacatg gacacgatga agcaggcggg ttatcaaaat
    18361 gtgtatgtct atagctatcg tagtttatta cagacgcgtt taaaacaccc agatatttta
    18421 aaacatgtaa actgggtagc ggcctatacg aatgctttag aatgggaaaa cccttattat
    18481 tcaggagaaa aaggttggca atatacctct tctgaataca tgaaaggaat ccaagggcgc
    18541 gtagatgtca gcgtttggta ttaagcgatg atttgaaaga gggatgtgat agtagcaccc
    18601 tctttttctt tgttttatga tagttcatcc tcgagtaaat tcaagatctt gcttggaaat
    18661 gaagcttata tagtagattg aatatagaca aataccttgt gattggtaaa acattttaga
    18721 aattcattta cctttcctaa tcgacttggt ttcatcttat ttcaatctat tatagtattg
    18781 gggaatttct tcaaaccaca tcagcttggt cagttctacc tgcgacctca aaacttgtgc
    18841 tttggtcaaa ctgggtttag tttcctagtt tgctgatgga tttccattga ctataagcat
    18901 ccaaccctct ttttgtcttc taaagaattc ttaaattatc agtctattgc aacttttctc
    18961 atataagttc tttgtcttgc tattggtttt ccttagtagt atactaaggt agtaatcatt
    19021 aagaagtggt tacaaaaaat aatgaatgag gtaaagaaaa tggtagaatt gaaaaaagaa
    19081 gcagtaaaag acgtaacatc attgacaaaa gcagcgccag tagcattggc aaaaacaaag
    19141 gaagtcttga accaagctgt tgctgatttg tatgtagctc acgttgcttt gcaccaagtg
    19201 cactggtata tgcatggtcg tggtttcctt gtatggcatc caaaaatgga tgagtacatg
    19261 gaagctcttg acggtcaatt ggatgaaatc agtgaacgct tgattacact cggtggaagc
    19321 ccattctcta cattgacaga gttccttcaa aatagtgaaa tcgaagaaga agctggtgaa
    19381 taccgtaatg ttgaagaaag cttggaacgt gttcttgtta tctaccgtta cttgtcagaa
    19441 cttttccaaa aaggtttgga tgtcactgat gaagaaggtg acgatgtgac aaacggtatc
    19501 tttgcaggcg ctaaaactga aacagataaa acaatttgga tgcttgcagc cgaacttgga
    19561 caagcacctg gtttgtaaga aataaggaaa catagataaa tctgtaggaa atttcttaca
    19621 gattttttct attttgtaag ctattccaaa ccagtctttt tttgagtttt ttgataaaat
    19681 agtactatca gtgaaaagga tggaagcatg actaagaaaa tcgtagctat ttgggcccag
    19741 gataaagagg gtgtgattgg taaggaaaat cgtctgcctt ggcatttgcc agcagaattg
    19801 cagcacttta aagaaacaac tctgaatcat gctatcttga tggggcgtgt gacctttgat
    19861 gggatggggc gtcgcttgct tccaaaacgg gaaaccctga ttttgacgcg taatccggaa
    19921 gaaaagatag atggggttgc tacttttcag gacgtccagt ctgttcttga ttggtatcag
    19981 gctcaagaaa agaatctcta cattatcggt gggaagcaaa tttttcaggc ttttgaagct
    20041 taccttgatg aagtgattgt cactcacatt catgctcggg tggaaggaga tacctatttc
    20101 cctggagagc ttgacttgtc tctttttgag acagtttcaa gcaaatttta cgccaaagat
    20161 gagaagaatc cttatgattt taccatccaa taccgcaaga gaaaggaagt ctaatggaac
    20221 ggagtttatt tggtctattc acggcttttc tgtgtttcat ctgctttctg gcaggagcac
    20281 aagcttttcg taaaaagcgt tacgggcttt ctatcctcct ttggttaaat gcctttacca
    20341 atctggtcaa tagtattcat gctttttaca tgaccttatt ttagatagaa tgacagtata
    20401 gaatggaagg aaatcatgtc tacaaataga aaaaatgata tgatggttta ttgctcattt
    20461 tgtggcaaaa accaagaaga agtacaaaaa ataattgctg gcaacaatgc ttttatttgt
    20521 aatgaatgcg tggagttagc tcaggaaatc attcgagaag aattggttga ggaagtcttg
    20581 gcagacttgt ctgaggtgcc aaaaccaatt gaactcctcc atatcttgaa ccactatgta
    20641 attggtcaag atcgtgccaa gcgtgccttg gcagtggcgg tttataatca ctacaaacgc
    20701 atcaatttcc acgatacacg cgaagagtca gaagatgtgg atttgcagaa gtcaaacatt
    20761 ttgatgattg gcccaactgg ttcagggaaa actttccttg cccagacctt ggctaagagc
    20821 ttgaatgtgc cttttgctat tgcggatgcg acagctctga cggaggctgg ttatgtgggt
    20881 gaggatgtgg aaaatatcct cctcaaactc ttgcaggttg ctgactttaa catcgaacgt
    20941 gcagagcgtg gcattatcta tgtggatgaa attgacaaga ttgccaagaa gagtgagaat
    21001 gtgtctatca cacgtgatgt ttctggtgaa ggggtgcaac aagcccttct caagattatc
    21061 gagggaactg ttgctagcgt gccgcctcaa ggtggacgca aacatccaca acaagagatg
    21121 attcaagtgg atacaaaaaa tatcctcttc atcgtgggtg gtgcttttga tggtattgaa
    21181 gaaattgtca aacaacgtct gggtgaaaaa gtcatcggat ttggtcaaaa caataaggcg
    21241 attgacgaaa acagctcata catgcaagaa atcatcgctg aagacattca aaaatttggt
    21301 attatccctg agttgattgg acgcttgcct gtttttgcgg ctcttgagca attgaccgtt
    21361 gatgacttgg ttcgcatctt gaaagagcca agaaatgcct tggtgaaaca ataccaaacc
    21421 ttgctttctt atgatgatgt tgagttggaa tttgacgacg aagcccttca agagattgct
    21481 aataaagcaa tcgaacggaa gacaggggcg cgtggacttc gctccattat cgaagaaacc
    21541 atgctagatg ttatgtttga ggtgccgagt caggaaaatg tgaaattggt tcgcatcact
    21601 aaagaaactg ttgatggaac ggataaaccg atcctagaaa cagcctagag gtgactatgg
    21661 aacttaatac acacaatgct gaaatcttgc tcagtgcagc taataaatcc cactatccgc
    21721 aggatgaact gccagagatt gccctagcag ggcgttcaaa tgttggtaaa tccagcttta
    21781 tcaacactat gttgaaccgt aagaatctcg cccgtacatc aggaaaacct ggtaaaaccc
    21841 agctcctgaa cttttttaac attgatgaca agatgcgctt tgtggatgtg cctggttatg
    21901 gctatgctcg tgtttctaaa aaggaacgtg aaaagtgggg gtgcatgatt gaggagtact
    21961 taacgactcg ggaaaatctc cgtgcggttg tcagtctagt tgaccttcgt catgacccgt
    22021 cagcagatga tgtgcagatg tacgaatttc tcaagtatta tgagattcca gtcatcattg
    22081 tggcgaccaa ggcggacaag attcctcgtg gtaaatggaa caagcatgaa tcagcaatca
    22141 aaaagaaatt aaactttgac ccaagtgacg atttcatcct cttttcatct gtcagcaagg
    22201 cagggatgga tgaggcttgg gatgcaatct tagaaaaatt gtgaggaaaa gaaaatggca
    22261 aaaacaattc atacagataa ggccccaaag gctatcgggc cctatgttca aggaaaaatc
    22321 gttggcaacc ttttgtttgc tagcggtcaa gttcccctat cccctgaaac tggggaaatt
    22381 gtaggagaga atatccaaga acagacagag caagtcttga aaaacatcgg tgctattttg
    22441 gcagaagcag gaacagactt tgaccatgtt gtcaaaacaa cttgtttctt gagcgatatg
    22501 aacgactttg ttccttttaa tgaggtttac caaacggcct tcaaagagga attcccagct
    22561 cgttcagctg tggaggtagc tcgtcttcct cgtgatgtaa aagtcgaaat tgaagtcatc
    22621 gcagagattg gataagctag ttgaagtttg gtgttgccaa acttcttttg atataaggag
    22681 aaaaagatga caaagaaaca acttcacttg gtgattgtga cagggatgag tggcgcaggg
    22741 aaaactgtag ccattcagtc cttcgaggat ctaggttatt tcaccattga taatatgccg
    22801 ccagctctct tgcctaagtt tttgcagctg gttgaaatta aggaagacaa tcctaagttg
    22861 gccttggtag tggatatgcg tagccgttct ttcttttcag agattcaagc tgttttggat
    22921 gagttggaaa atcaagatgg tttggatttc aaaatcctct ttttggatgc ggctgataag
    22981 gaattggtcg ctcgttacaa ggaaaccaga cggagtcacc cactagcagc agacggtcgt
    23041 attttagatg gaatcaagtt ggaacgtgaa ctcttggcac ctttgaaaaa tatgagccaa
    23101 aatgtggtgg atacgactga actcactcca cgtgagctgc gcaaaaccct tgcagagcag
    23161 ttttcagacc aagaacaagc ccagtctttc cgtatcgaag tcatgtcttt cggatttaag
    23221 tatggaatcc cgattgatgc ggacttggtc tttgatgtcc gtttcttgcc aaatccctat
    23281 tatttaccag aactgagaaa ccaaacgggt gtggatgaac ctgtttatga ttatgtcatg
    23341 aaccatcctg agtcagaaga cttttatcaa catttattgg ccttgattga gccgattctg
    23401 ccaagttacc aaaaggaagg taagtccgtt ttgaccattg ccatgggatg tacgggtgga
    23461 caacaccgta gtgtggcatt tgctaaatgc ttggcgcagg acttatccaa gaattggtct
    23521 gttaatgaag ggcatcgcga caaagaccgc agaaaggaaa cggtaaaccg ttcatgagaa
    23581 aaccaaagat aacggtgatt ggtggaggga ctggaattcc cgtcattcta aaaagtctgc
    23641 gggaaaaaga tgtggaaatc gcagctatcg tgacggtggc agatgatggt ggttcttcag
    23701 gtgaactccg aaaaaatatg caacagttga caccgccagg tgatcttcgt aatgtccttg
    23761 tggccatgtc ggatatgcct aagttttatg agaaggtctt tcagtatcgg ttctctgagg
    23821 atgccggagc ctttgctggc catccattgg gaaatctcat cattgctggc ttgtcagaaa
    23881 tgcagggttc aacctataat gccatgcagt tattgagcaa atttttccat acaacaggga
    23941 aaatttatcc ttccagtgac catcctttga cccttcatgc agtctttcag gatgggacag
    24001 aagtggctgg agagagtcat attgtagacc atcgaggcat aattgacaat gtctatgtga
    24061 ccaatgccct aaacgatgat acgcctctgg ccagccgtcg agtagtgcag accatccttg
    24121 aaagtgacat gattgtccta gggccaggtt ccctctttac ctctattttg cccaatatcg
    24181 tgattaagga aattgggcgg gctcttttgg aaactaaggc agaaattgcc tatgtctgca
    24241 atatcatgac ccaacgtggg gagacggaac actttacaga tagcgaccac gtggaagtct
    24301 tgcatcgtca ccttggtcgc ccttttatcg acactgtctt ggtgaatatt gaaaaagtgc
    24361 ctcaggaata catgaattcc aaccgttttg atgaatactt agtgcaagtg gaacacgatt
    24421 ttgtaggtct ttgtaagcaa gtttcgcgcg tgatttcatc taacttcctt cgtctggaaa
    24481 atggcggtgc cttccacgat ggagatttga ttgtggacga gttgatgcgc attatacagg
    24541 tgaaaaaatg agtttcacag tagcagtaaa agaagaaatc ctgggccaac accacctgag
    24601 ccggcatgaa ttatctgcca ttatcaaaat gtctggtagc atcggtctct cgacttcggg
    24661 cttgactttg tcagttgtga cagaaaatgc caaactggcc cgtcacctct atgagtcctt
    24721 tctccatttc tatgaaatca aatctgaaat tcgtcactac caacggagca atcttcgcaa
    24781 gaatcgcgtc tataccgttt ttacagatga aaaggtgcag gatttgttaa gtgatttgca
    24841 cttggcagac tctttctttg gcctggaaac aggtattgat gaggcgattt tatcggacga
    24901 ggaagcaggt cgtgcctatc tctgtggcgc tttcttggca aatgggagca ttcgtgaccc
    24961 tgagtcaggc aagtaccagt tggaaatcag ttctgtttat ctggaccacg cgcaaggaat
    25021 tgcctccctt ctccaacagt ttttactgga tgccaaggtg cttgagcgca agaagggggc
    25081 tgtgacctat ctccagcgag cagaagacat tatggacttc ttgatagtaa tcggagccat
    25141 gcaggcacgt gatgattttg agcgggttaa gattttgcga gaaacccgta acgacctcaa
    25201 tcgggctaat aatgccgaga cagctaatat cgctcggaca gtttctgcca gcatgaagac
    25261 cattaacaat atcagtaaaa tcaaagatat catgggctta gaaaatttgc cagtagattt
    25321 gcaggaagtg gcgcaactga ggattcagca cccagactac tctatccagc agttagcaga
    25381 tagtctcagc acccctctga ccaaaagtgg tgtcaatcac agactcagaa aaatcaataa
    25441 gatagcggat gaattataaa accacgaatc ctatgtgact cgtggttctt ttttataaac
    25501 tagtagagtg ttttggttgt actttttgtt cagggtcaat gtagttgata gcgttgttga
    25561 cagcagttgg agcttctccg aggcctgtcg caatcagatc aatttttccg tcatagtagc
    25621 agcagtcacc gatagcatag atacctgctt ggctggattc ctgtttgctg ttgacgataa
    25681 tcttgtgacg gttgaggtcg agcccccagt ttttaaggtt accgacagaa gatttgaaac
    25741 catagttgac aaagaggtgg tctaggtcaa tggtttcagt ttcatcagat ttgacttttg
    25801 tgatttcaag tttatcaagt gtttttccat ttccaaggag ttggctaggg gcgaatggtg
    25861 tcttgatggt tacagatgat tcttgcaagg cttgaacact gtgttccaag gcacggaaat
    25921 tatctctgcg gtgaacaagg gtagttggtg cgattttttc aaaagccaaa gcccaatcca
    25981 cagccgagtc tcccccacca agaatcgtca ctttcttacc agcgtattgc tgaatgttag
    26041 aaacgtggta gtggatattt tcatagccct caaccccttc aagttccagc ggacgtggtt
    26101 tgaaggcacc gccacccata gcgatgataa ctgttttagt caggtgactt cctttagaag
    26161 ttgtgatggc aaattcttct tgtttgtcaa tctcaagaac cgtttcattg agatgaatag
    26221 gggtatcaaa tccatttagc tgttcaatca agcggttagt caactcttct ccagtcaggt
    26281 ttgggaagcc tggtacgtct aggatttcct tttcagggta gagaatagca ggttgtccac
    26341 ctagctgggg aagagagtcg atgatttgaa ccttggcttg gcgtaggtgg gcataaaagg
    26401 ctgcaaaaag cccgacagga ccaccaccca caatggtaat atcatagagt tgagacatag
    26461 tttctccttt gttttttcta gtcagtttat tttatcatat ttttgttcaa tgtaaaatgg
    26521 actaggatag ggaaaaaaat gccagaaaat ggtataatag gacgaaagtg ttttgatagg
    26581 gaggatatca gggatgaatt ttcaacaatt atccaatctg caatattgga ccagtttgtt
    26641 tgcaagtcca tggacgatag ctatcaatct gattgatatt ttgattgttg cttatatttt
    26701 ataccatttt acaaaagcta ttgcaggaac caagattatg attttggtac gtggagtttt
    26761 ggtgtttatt ttagctcaaa tccttgcaaa tatgattggt ttgactacga tttcttggtt
    26821 aatcaatcaa attattactt atggggttat tgcggcggtt gttatcttct ctccagagat
    26881 tcggactggt ttggaacgtt tgggaagagc gacagatttt ttttccaatg cccctattag
    26941 tgctgaggaa cagatgattc gtgcctttgt taagtctgtt gaatacatga gtcctcgtaa
    27001 aatcggggcc ttggttgcta ttcagcgtgt acgtaccttg caggagtata tttcgacagg
    27061 aattcccttg gatgctaaga tttctgcaga acttctcatt aacattttta ttcccaacac
    27121 tcccctacat gatggtgcgg tgattatcaa agaagaacgt atcgctgtga cgtctgccta
    27181 tctgcccttg acaaaaaaca cagggatttc caaggaattt gggaccagac accgggcggc
    27241 tatcggttta tcagaagtct cagatgcctt gacttttgtc gtatcagagg aaacgggagg
    27301 aatttcgata acctataatg gaaggtttaa gcacaaccta acacttgatg aatttgaaac
    27361 agaattacgt gaaatcttac ttccaaaaga ggaagtgggt cttagtttta aagaacgatt
    27421 gctaggagga tggaaacatg aaaaaaaata gtttatatat catatcctca ctcttttttg
    27481 cttgtgtctt atttgtctat gctacggcga cgaattttca aaacagtacc agtgctaggc
    27541 aggtaaaaac ggaaacctat actaatacag taacaaatgt ccctattgac atacgctata
    27601 atagtgataa gtattttatt agcggttttg cttcagaagt atcagtggtc ttgactgggg
    27661 caaatcgcct atcgctagct agtgaaatgc aagaaagtac acgtaaattc aaggttactg
    27721 ctgacctaac agatgccggt gttggaacga ttgaagttcc tttgagcatt gaagatttac
    27781 ccaatgggct gaccgctgta gcgactccgc aaaaaattac agtcaagatt ggtaagaagg
    27841 ctcagaagga taaggtaaag attgtaccag agattgaccc tagtcaaatt gatagtcggg
    27901 tacaaattga aaatgtcatg gtgtcagata aagaagtgtc tattacgagt gaccaagaga
    27961 cattggatag aattgataag attatcgctg tcttgccaac tagcgaacgc ataacaggta
    28021 attacagtgg ttcagtacct ttgcaggcaa tcgaccgcaa tggtgttgtc ttaccggcag
    28081 ttatcactcc gtttgataca ataatgaagg tgactacaaa accagtagca ccaagttcaa
    28141 gcacatcaaa ttcaagtaca agcagttcat cggagacatc ttcgtcaacg aaagcaacta
    28201 gttcaaaaac gaattaaaaa tagaaaagga ttttataaca atgggtaaat attttgggac
    28261 tgatggagtc cgtggagaag ctaacctaga actaacacca gaattagcct ttaaactagg
    28321 acgttttgga ggctatgttc ttagtcaaca tgaaacggaa gcgccgaaag tctttgtagg
    28381 acgtgacaca cgtatttcag gggaaatgct ggaatcggcc ttggtggcag gtctcctttc
    28441 agtagggatt cacgtataca aacttggtgt ccttgcaaca ccagcagtag cttacttggt
    28501 tgaaactgaa ggagcaagtg ccggtgtcat gatttctgct agccacaacc cagcccttga
    28561 taacggaatc aagttctttg gcggtgatgg cttcaaacta gatgatgaaa aagaagcaga
    28621 aattgaagcc ttgctagatg ctgaggaaga cactcttcct cgtccaagtg cagaaggctt
    28681 aggaattttg gtagattatc cagaaggctt gcgtaagtat gaaggatacc ttgtttcaac
    28741 tggaactcct cttgatggaa tgaaggttgc cttggataca gctaatggag cagcttctac
    28801 cagtgcccgt caaatctttg cagaccttgg tgcccaattg acggttatcg gggaaacacc
    28861 agacggtctt aacatcaacc ttaatgttgg ttcaacacat ccagaagccc ttcaagaagt
    28921 ggtcaaagaa agtgggtcag ctattggttt ggcctttgat ggagacagtg accgcttgat
    28981 tgctgttgat gagaatggtg acatcgtcga tggtgacaag attatgtaca tcatcggaaa
    29041 atacctttct gaaaaaggac aattggctca aaatacaatt gtgacaactg ttatgtctaa
    29101 ccttggtttc cacaaggcct tgaatcgcga aggtattaac aaggcagtta ctgcagttgg
    29161 tgaccgctac gttgttgaag aaatgagaaa atcaggctac aaccttggtg gtgaacagtc
    29221 tggtcacgtt atcttgatgg attacaatac cacaggtgat ggtcaattat cagcagttca
    29281 attgactaaa atcatgaagg aaactggtaa gagcttatca gagttggcgg cagaagtaac
    29341 gatttatcca caaaaattag ttaatatccg agtggaaaac gtcatgaagg aaaaggccat
    29401 ggaagtgcca gctatcaagg ccatcatcga gaagatggaa gaagaaatgg cggggaacgg
    29461 ccgtatcctt gttcgtccaa gtggaacaga gcccctcttg cgtgttatgg cagaagcgcc
    29521 tacaacagaa gaagtggact actatgttga taccatcaca gatgtagttc gtgctgaaat
    29581 tgggattgac taaatcctag aaaactagat gaaaataaaa aattatggta caatagctta
    29641 taatattgta gccgatggag aaagacatga atcttaaacg tgaacaagaa tttgttagtc
    29701 agtatcattt tgatgcgcgt aattttgaat gggaaaatga aaatggagct cctgaaacca
    29761 aggtggatgt gaatttccaa ttgctccaac atgaccaaga aaatcaagtg acttccttga
    29821 ttgtcatctt gagctttatg attgtatttg ataagtttgt cattagtgga acaatctcac
    29881 aagtaaacca tatcgatggc cgtattgtca atgaaccaag tgaattgaac caagaagagg
    29941 tggaaacctt ggctcgtcca tgtttgaaca tgctcaatcg tttgacttac gaagtgactg
    30001 aaattgcatt agacttacca ggaattaatt tggagttcta atatgaaatt agctgttttc
    30061 acagattcct ctgcttatct cagtgaagag accttgcaaa gagaagactt gtttgtcttg
    30121 gatattcctg tcaatattga tggtgaggaa tatgtcgaag gcatcaatct gtctgctgag
    30181 gaattttacc aaaaaatggc tcaggcttct gaattgccta agaccagtca accaagtatt
    30241 gccaagttag atgagatctt aacttcgctc aaagaacaag gctatacaca tgccttgggg
    30301 cttttcctat cttctggaat ttcaggtttt taccaaaata tccagtatat ggtcgatgac
    30361 tatgagggct taaccattgc tttcccagac actttgatta caagtgctcc cctaggcatc
    30421 atggttgaaa gcgtctttaa ttggcgtgat cagggcgatg attttgccag cattcaggat
    30481 aagctagcca ttcaaatcag ccgtacgtca gcctttatca tggtagatga cttggatcat
    30541 ttggtaaaag gtggacgcct ttcaaatggg gctgccattt tgggcaattt gcttagcatt
    30601 aagccaatcc tttattttaa cgatcaaggt gtgattgaag tttacgaaaa agttcgtact
    30661 gaaaagaagg ccaccaaacg cttaattgaa attatcaagg aaacaacggc ttcaggtcaa
    30721 taccgggtca ttgtcattca tgggaatgat cctgaaaagg ctgaagaatt gcgtcagcat
    30781 ttgcttgatt ttggcttggg ttcggatgtt tcacttgcta catttggtag tgtcattgga
    30841 acgcacctag gagcaggaag tattgctctg ggttatattc cagtgattta gtaggcactt
    30901 ctaggctagt taatcttagc aattgaacac ggactacctg cctcttgaaa aaagatgtct
    30961 gtcttgcctt tcgtggaaag tcagtgccat tccctatttt tcatgggtgg ctaagatcct
    31021 ttgtattttg ataattgaac acgcctggaa ccctgtgtga aaaagatagt tcttccaagg
    31081 agtagacact tcttgatcag aattcctatt ttcactttgt gttcttacag gctttgtatc
    31141 ttagacagga gtagagatga gtattcgagt aattattgcc ggttttaagg gaaagatggg
    31201 tcaagctgct tgccagatgg tcttgcctga ttcagatttg gacttggtag cagttttgga
    31261 tccttttgag tctgagtcag aatggcaggg tattcctgtt ttcaaggata aggctgattt
    31321 agctggtttt gaagcggatg tctgggtaga ctttactact ccagctgttg cctacgaaaa
    31381 tacacgtttt gctcttgaaa atggctttgc tccagtagtt ggaacgactg gtttcacgag
    31441 tgaagaaatt gcagagttaa aagaattttc tcgtgcccaa gacttgggtg gcctgattgc
    31501 ccctaacttt gccttgggtg ctgtcttact catgcaattt gcgacgcagg ctgccaaata
    31561 tttcccaaat gtggagatta ttgagctcca tcatgacaag aaaaaggatg ctccgagtgg
    31621 aacagccatt aaaacagctg agttgatggc agaggttcga gagtccattc agcaaggcgc
    31681 agcagatgag gaagagctga ttgctggtgc tcgtggtgct gactttgatg gtatgcgcat
    31741 ccactcagtt cgtttgccag gtttggtagc ccatcaggaa gtcatctttg gcaatcaagg
    31801 agaaggattg accctccgtc atgactccta tgatcgcatc tccttcatga caggagtcaa
    31861 tttgggaatt aaagaagttg tcaagcgtca tgagcttgtc tatggattag aacacttatt
    31921 atgagattaa cgcaaatgcc ttctgaattt cagaaggctt taccagtatt agaaaaaatt
    31981 aaagaagcag gctttgaggc ttattttgtt gggggctctg ttcgagatgc ccttctccat
    32041 agccctatcc acgatgtgga tattgcgacg tcttcttatc cagaagagac caagcagatt
    32101 tttccgcgaa cagccgatat cggaatcgag catggaaccg tcttggtctt agatggggat
    32161 gaggagtatg aggtaacaac ctttcggaca gaggatgtct atgtggacta tcgcagaccc
    32221 agtgcggttt cctttgtgcg ctcgctagaa gaagacctca aacgccgtga tttcacagtc
    32281 aacgcctttg ccttggatga gacaggagaa atcgttgact tgttccatgg tttagaagat
    32341 ttggaaaagc aagtcttgcg agcagttgga gtggctagtg agcgtttcaa cgaagatgct
    32401 ttacggatta tgcgtggttt ccgttttcag gctagtcttg gttttgcact tgagccagaa
    32461 acatttaaag ctatgaagac cttgacgccg cttttggaga acatttctgt agagcgtacc
    32521 ttcgtcgagt ttgataaact cttgctggct ccattttgga gaaggggctt ggcttccatg
    32581 attgagagtc aagcttatga ctatctccct gatatggcat ctagccagaa caagctcaac
    32641 agactgtttg atttggagac tgattttact tttgaatcct ctgaacaagc ctgggcggct
    32701 ttactatggg ctttggagat tgaaaatgcg cagtcatttt tgaaatcttg gaagacctca
    32761 cgccagtttg ccaagcaagt tcaggatttg ctgattattt tggctctgcg tgaaaatgga
    32821 gaattgagca agcgagattg ttatcgcttt gacatagatt tgcttttaca ggctgaaaat
    32881 cttcgtcaag ctcgaggaaa agaagtcaac ccacaagcca tcacagaaaa ataccaaagc
    32941 ttgactatcc atgacaagaa agagattcag attaatggcg atattttgat caaggaatat
    33001 ggctatcagc caggcccaga cttgggagag attttaacag agattgagtt tgccattgtc
    33061 gatggagaat tggagaataa tcgtgaagcc atccatgctt acctgaggga gaaaaaatga
    33121 gtgattttat cgttgaaaaa ctaagtaaat ccgttggtga caagaccgtt tttagggata
    33181 tttcctttat tatccatgac ttagacagaa ttggtttaat cggtgtcaat gggactggca
    33241 agaccaccct tttggacgtc ctttctggtg tttctggctt tgatggggat gtcagtcctt
    33301 tttcagctaa aaatgattac cagattggtt acttgactca ggatcctgat tttgatgata
    33361 gaaagacagt tttggatacg gttctatcta gtgaactcaa ggaaatccag ctcattcgtg
    33421 agtatgaatt gattatgctc gactatagtg aggacaagca ggcgcgtttg gaacgtgtca
    33481 tggcagagat ggactctctc caagcttggg aaatcgagag tcaggtcaag accgttctta
    33541 gcaaattggg cattcaagac ttatctactc ctgttgggga attgtcaggt ggtctgagaa
    33601 gacgggtaca gttggcacaa gtcttacttg gcaaccacga cctcttgctt ttggatgagc
    33661 cgaccaacca tctggatatt gcgattattg agtggctgac cctctttttg aaaaattcta
    33721 agaagaccgt cctttttatc actcacgatc gttatttctt agacgctttg tcaacacgga
    33781 ttttcgagtt ggagcgagca ggcttgacag aatatcaggg caattaccag gactatgttc
    33841 gccttaaggc agaacaggac gagcgcgatg caactctact tcataaaaaa gaacaactct
    33901 acaaacaaga actggcctgg atgcgcagac aaccgcaggc acgtgcgacc aagcaacaag
    33961 ctcgtatcaa tcgtttccat gatctgaaaa aggaagtttc aggcagtagt gctgagacag
    34021 acttgactat gaactttgaa accagtcgga ttgggaagaa agtcatcgag tttcaggatg
    34081 tttcctttgc ctatgaaaat aagcccattt tgcaagattt taatctcttg gtacaggtca
    34141 aagatcgtat cggaatcgtt ggggacaatg gtgttggaaa atcaacccta cttaacctga
    34201 ttgcaggaag tcttgagccg atagcaggac aagttgtgat tggggaaact gttcgcatcg
    34261 cctatttctc tcaacaaatt gagggtttgg atgaaagcaa gcgtgtgatc aattacctgc
    34321 aggaagtggc agaggaggtc aagaccagtg gtggttctac gacttccatc gctgagttgc
    34381 tggagcaatt cctcttccca cgttcgacgc atgggccttg attgagaaat tatctggtgg
    34441 agagaaaaaa cgtctttatc tcctcaaact gctcttggag aaaccaaatg ttcttctttt
    34501 agacgagcca accaatgact tggatattgc aactttgaca gtcttagaga atttcttgca
    34561 aggttttgca ggtcccgttt taacagtcag tcacgaccgc tatttcttgg ataaggtagc
    34621 gaccaagatt ctcgcttttg aggatggcaa gattcgtcct ttctttggtc attacaccga
    34681 ctatcttgat gaaaaagctt ttgaaacaga tatggccaat caagtgcaaa aggccgaaaa
    34741 ggaaaaagtg gtcaaggttc gagaagacaa gaaacgcatg acctaccaag aaaagcagga
    34801 gtgggcaagt attgaaggtg atattgaaac cttggaaaaa cgtatcgctg ctattgaaga
    34861 ggaaatgcag gctaacggct ctgactttgg taagctggct actctccaaa aagaattgga
    34921 tgagaaaaat gaagcactcc ttgaaaaata cgaacgctat gagtatctca gtgaatttga
    34981 tagttaagac tattcgaaaa tcaaagtgca aactatgtcg gcttcacatt gccgactcaa
    35041 gtacagcctg tgaccggctt cctaatttgc actttgattt ttattgagta taaaagaata
    35101 gaaaaatccc gtctcatgaa aggatttctc tattcttttt tggtttcttg atgaaagata
    35161 ttttgccagg tttcgtggcg acgccagata ctggtatgga tgataccatc taactcatag
    35221 cagatgagtt tggttttttg actgatggaa gtaatttgaa tgtccttgat agcagaattt
    35281 aactcttttt tggtcttata agcctcttta tccatctgct ctccatcttg gcgaatatag
    35341 acaaaatcat cagtcaagag ttcttctagt tggtttcctt ggtcaatcaa ttgttcacgc
    35401 ataagcaatt ttttatagac attgtctaaa atttcatcct cagggatagg tgctggttcg
    35461 atatggacat cggtatcaaa gacgccaaaa cgctcctcca gcatagactc gacctgatcc
    35521 gcgatttcat ggctttcaaa aacagacaag tcaggattca tctctagtgt aatatccagg
    35581 tagatgttgc taccgtaggt gcgacctctt tgcgatttga ccttgctgat tttgggaatt
    35641 tccatgatag ccttttggta gtcctcgagc aggcggtcgt caaagccatc tgaaagacta
    35701 aaggaagact cgatgaagat atcataggca gtcttcaaga taaagaaagt gatgatgata
    35761 gcaaccagtt tatccacaat cggataattg aaactactag ctaggatggc aatggcggtt
    35821 ccaagtgagg taacagcgtc agaaagattg tccttagcag ctgccttcag cgccttggag
    35881 ttggatttct tactgaggcg agtattgtag agatagacca caaacataat cgctgcagaa
    35941 atgattccta gagttgcacc aagaggatca atgaccgttt cttcccgact gagaatcttt
    36001 tgaatggtat ctcttagaat atcgaaaccg acatagaaca tgatgataga agtgatcaag
    36061 cttgccaaat cttcaatctt ccaatgacca aaacggtggt cacggtctgc aggctggcgc
    36121 gccatccgaa tcccgattaa gagggccaca tttccaatga tgtccgatac gttattaaaa
    36181 ccatcggcca ccaaactgga tgaatgaagg agatgaccag ctgctaattt agctgcagac
    36241 aagatcaaat aggtcgaaat actgataatg gctccacgct cagctaactt gagatttgag
    36301 atagattgct tcattcaact tcctttctag tcacatagca ttctaccatt atactggttt
    36361 tcaaggaaaa attcaaataa ggcagttttt actctttgaa aactccccaa aatttggtat
    36421 aatggtacta ctcaagggag tagctggcag aaacctgtga tagtgtcgtc attccgaatt
    36481 ttatgctgaa aagtatgctt tccggcccta tcttaaacag cgagacttgt tatgattaac
    36541 aggtctcttt ttgtttgtcg tgaaaagata tgacagaaag agagtctgtt ttgcacacaa
    36601 tgtcaaggag gagacacatg tcaaaagaac aaaaacgcca agcgttttat actcagagcc
    36661 ctgaagaggt cttgcaggct gtggatgcga ccgagcaagg tttgtcatca agtgaggcgg
    36721 aaaagcgcct tgccgaattt gggcacaatg aactcgaaga aggcgagaaa cgatcaatct
    36781 tggtcaaatt catcgagcaa tttaaggatt tgatgattat catcctagtt gcggcagcaa
    36841 tcttgtcagt cgtgacttct ggtggggaag atatcgcaga tgccattatc atcctagctg
    36901 tggttatcat caacgctgcc tttggtgttt accaagaagg aaaagctgaa gaagctatcg
    36961 aagccctcaa atccatgtct agtccagttg cccgcgttct tcgtgatgga cacatggcag
    37021 agattgactc taaagaattg gtaccaggcg atatcgttgc ccttgaagca ggtgacgtgg
    37081 taccagcgga cctacgtttg ctagaagcca actctcttaa aattgaagaa gcagccttga
    37141 cgggtgaatc tgtaccagtc gaaaaagact tgtcagtcga gcttgcgaca gatgctggta
    37201 ttggtgaccg tgtcaacatg gccttccaaa actcaaacgt aacctatggt cgtgggatgg
    37261 gtgttgttgt caatacaggt atgtacactg aagttggtca tattgctggt atgcttcaag
    37321 atgcggatga gactgataca ccactcaaac aaaacttgaa caacctttct aaggtcttga
    37381 cctatgctat cttggtcatt gcccttatta cttttgtagt gggtgtcttc attcaaggga
    37441 aaaatccact tggtgagttg ttgacttctg ttgcccttgc cgttgcagcc attccagaag
    37501 gacttcctgc tatcgttacc atcgttcttt ctcttggtac tcaagttttg gccaaacgac
    37561 attccatcgt tcgtaagttg ccagcagttg aaacacttgg ttcaactgaa atcatcgctt
    37621 ctgataagac tggtacgctg actatgaaca agatgacagt cgaaaaagtc ttctacgatg
    37681 cggttctaca tgactcagct gatgatattg aactaggtct tgaaatgcca ctacttcgtt
    37741 cagttgtctt ggccaatgat acgaaaatcg atgtggaagg taacttgatt ggtgacccaa
    37801 ccgaaacagc ctttatccaa tatgccttgg acaagggcta tgatgtcaaa ggtttcttag
    37861 agaaatatcc tcgtgtagct gaattgccat ttgactctga ccgtaagctc atgtcaacag
    37921 ttcacccatt gccagatggt cgtttccttg tagcagtcaa gggtgcgcca gaccaactct
    37981 taaaacgttg tcttcttcgt gataaggctg gggatattgc tccgattgat gagaaggtta
    38041 caaatctcat tcatacaaac aattctgaaa tggctcatca agccttgcgt gtccttgcag
    38101 gtgcttataa gattatcgat agtattccag aaaatctcac ttctgaagag cttgaaaatg
    38161 atttaatttt tactggtttg attgggatga ttgaccctga acgtcctgaa gccgctgagg
    38221 ctgttcgtgt ggctaaggaa gcgggaatcc gtccgattat gattacaggt gaccaccaag
    38281 acacagcgga agccattgcc aaacgtttgg gaatcattga cgcaaacgat acagaaggtc
    38341 acgttttaac tggtgctgaa ctcaatgaac tgtcagatga agaatttgaa aaagtcgttg
    38401 gtcaatactc tgtttatgcc cgtgtgtctc cagaacacaa ggttcgtatc gtcaaggctt
    38461 ggcaaaaaca aggtaaagtc gttgccatga caggtgacgg tgtcaatgac gcgccagctc
    38521 tgaaaacagc cgatatcggt atcggtatgg gaatcactgg tacagaggtt tctaaggggg
    38581 cttctgatat gattcttgca gatgataact ttgcgactat tatcgtcgca gtggaagaag
    38641 gacgtaaggt cttctcaaac attcaaaaga ctattcagta cctactttct gctaatactg
    38701 ctgaagtatt aaccatcttc ctatcaacct tgtttggttg ggatgtctta cagccggttc
    38761 atcttttgtg gatcaacttg gtaacggata ccttcccagc tatcgctctt ggtgttgaac
    38821 ctgcggaacc tggtgtcatg aatcataaac cacgtggacg caaggcaagc ttcttctcag
    38881 gtggtgtttt gagttctatc atttatcaag gtgtactcca agcagctctt gttatgagtg
    38941 tttatggcct tgcgattgct tacccagttc atgtgggtga caatcatgct attcatgcag
    39001 atgccctaac gatggccttt gcaacccttg gtttgattca gctcttccat gcctacaatg
    39061 tcaagtctgt ctaccaatcc atcttgacag ttggcccatt caagtctaag acctttaact
    39121 ggtccatctt ggtatccttt atccttctca tggcaacaat cgttgtagaa ccgcttgaag
    39181 gaatcttcca cgtaaccaaa ctagacttgt cacaatgggg aattgttatg gctggaagct
    39241 tctcaatgat tatcatcgtc gaaatcgtta agtttattca acgcaaactc ggttttgaca
    39301 agaatgcgat ttaagggagg tttcggatgt cagcatatca attaccgacc gtatggcagg
    39361 atgaagctag taatcaagga gcttttacgg ggctaaacag accaacagca ggtgcccgtt
    39421 tcgaacaaaa cttgccaaaa ggagaacaag cttttcagct ttattcactg ggaacaccaa
    39481 atggtgtgaa ggttactatc ttattggaag aattactaga agctggtttt aaggaagcgg
    39541 cttacgactt gtataagatt gctatcatgg atggggatca attcggctca gactttgtga
    39601 agctcaatcc aaattccaag attccagcct tattggacca gtcaggtact gaaaacgtaa
    39661 gagtctttga gtctgctcat attcttcttt accttgctga gaaatttgga gcctttttac
    39721 caagtaatcc tgtggaaaag gtagaagttt tgaattggct attctggcaa gcaggtgcag
    39781 caccttttct aggtggggga tttggacatt tcttcaatta tgctcctgaa aaattggaat
    39841 atcctattaa ccgttttacg atggaagtga aacgccagtt ggatttattg gataaggaat
    39901 tggctcagaa accttatatt gcaggcaatg actatacgat tgcagatatt gctatctggt
    39961 cttggtatgg acagttagtt caaggaaatc tttaccaagg ttctgcaaaa ttcttggatg
    40021 cctcaagtta tcaaaatcta gtaaaatggg cagaaaaaat tgccaatcgt ccagctgtta
    40081 agcgtggctt ggaagtaact tatacagaaa ttaaatagca aaaaagtcat cttcggatgg
    40141 ctttttgcta cagttgaggg aaagggtttg cagttatcgg cttttgtgct ataattgcta
    40201 taatatagta aaaagcaaga ggagtgtgag gaagtggaaa agaaaattgt gaaggatatc
    40261 ttatttttat ctcaagtgtc tcagccggca agtcaggagg acctttatct tgccagagat
    40321 ttgcaggata cactcttagc aaatcgtgat acctgtgttg gtctagctgc caatatgatt
    40381 ggggtgcaga agcgcgtgat tatctttaat cttggcttgg ttcccgtggt catgtttaac
    40441 ccagtgcttc tgtcctttga aggatcctat gaggcagaag aaggctgttt gtccttggta
    40501 ggtgtgagat caactaagcg ttatgaaacc acaaggcttg cctatcgtga cagcaagtgg
    40561 caggaacaga ccattacctt gacaggcttc ccagctcaga tttgccagca tgagctggat
    40621 cacttggaag gacgaatcat ttaggaggaa agcaaatgaa acgaatagtc tttgaactta
    40681 tttttatcgc aacgacctgg tatatctttt taccgcccct taacctgacc agctgggaat
    40741 ttctcttctt cctctgtggg catttgttag ttgtggcaat cttatttggc tttggcaagg
    40801 ggataaacct tgtcaaaacg gttcatgtgc gccacggtaa ggcggaagct gccttaaatc
    40861 ttgagggttt caaaatcaat cggttaggga aaattctgtt agcttcgatt ggaggaattc
    40921 ttctcttggc agctttggtt tccttggtaa cttccagcat gtttcaggct aaaaattatg
    40981 ccaatgtagt cacggttacg gaaaaagact ttactgaatt tcctaggagt gacaccagta
    41041 aggttcctat cctagataga agtactgctg aaaaaattgg agaccgctac ttgggttccc
    41101 taaccgataa ggtgtcgcaa tacgtagcgg cagataccta tacccaattg acaattgatg
    41161 ggaaacctta tcgggtcaca ccactagaat atgcagaccc tatcaaatgg tttaacaatc
    41221 aagccaaggg aatcggtgag tatatcaagg tggacatggt aactggaaat gcggatttgg
    41281 tggacttgaa gacaccaatc aagtattcag actcggagta ttttaaccgt gatgtcaaac
    41341 gtcacctgcg cttgaagtac ccgactaaaa tctttaaaac tccatctttt gaggtggacg
    41401 atgagggcaa tcctttctat gtagcaacgg tttaccaaaa gcaatttgga cttgcggttc
    41461 ctcgtcctgc ttcagtcatt atcttggatg ctacaaatgg agaaaccaag gaatacagct
    41521 tatcagatgt tccagaatgg gtggacagga tctatccagc agaggaaacc attgagcaaa
    41581 tcaactacaa cggcaagtac aaggacggtt tcttgaatgc catgatttcc aagaaaaacg
    41641 tgacccagac taccaatggc tataattact tgtctatcgg taatgacatc tatctctaca
    41701 caggtgtgac gtcggctaat gcggatgaga gtaatcttgg tttcatcctt gaaaatatgc
    41761 gaacaggaga aattactaag tatagcttgg cttctgcgac agaagaatca gcccgtgaat
    41821 cagcagaagg tgctgttcag gagaaatcct acaaagcaac cttcccaatc ctcatcaacc
    41881 tcaatgacaa gcctctctac atcatgggct taaaggacaa tgctggcttg gtcaaagagt
    41941 acgccctggt agacgcagtc gagtaccaaa atgttatcgt tgctactaca gtggaagaga
    42001 tgctcagcaa gtatgccaat aaaaacgacc ttgaaattga caatgcaacg acagaaagca
    42061 tcaagggagt agtagcagac ctcaaatcag ctgttatcaa gggagacact gtctacttct
    42121 ttaaagttga tggcaagata tacaaggtaa aggcttcagt atccgatgac cttccttacc
    42181 ttgaaaatgg taaaaccttc gaaggtcaag taggaaaaga caattatctc aagaccttta
    42241 aagtacaata atactcttcg aaaatctcta gctctatctg caacctcaaa acagtgtttt
    42301 gagcagcctg cggctagttt cctagtttgc tctttgattt tcattgagta taaaaaaggt
    42361 ttatttaata aatatatgtt ataatagagt aaattaagac taatggagga caaagaaatg
    42421 ggtttttatt tgatggttgc ttcaatgcta ctcggactgc tcgctttgaa gataggtttt
    42481 tctcagttca aggagaaaaa agataaattc ttatctatct taacaagttt agctggcaca
    42541 gcccttgttc tcgtggctgt ctggttagga tggcccaaat aaatagaaaa acctcggtca
    42601 aaccgaggtt tttcaaatga atttcttggt tgtggctaaa aaatatgcta cactatcaat
    42661 atgaaaattt taatcccaac agcaaaagaa atgaacacag acttgccaag tatcgaggca
    42721 attcctttaa aaccagaaag tcagaccgtg cttgatgcct tggctctcta ttctgccagt
    42781 caattggaga gtttctacaa ggtatcagct gagaaagcgg cggaagaatt tcaaaatatc
    42841 caagctttga aaaggcaaac tgctcaacac tatccagcct tgaaactttt tgatgggctt
    42901 atgtaccgca acattaagag agataagctg accgaggcgg aacaagatta tcttgaaaat
    42961 catgtcttca ttacctcggc tttgtacggt gttgttccag ccttgtcacc catggctcct
    43021 caccgtttgg attttttgat gaaattaaaa gtcgctggta agactttgaa gagccattgg
    43081 aaggcagtct atgatgaagc tctgaagaag gaagaagtga ttttctctct cttgtcatca
    43141 gagtttgaga ctgtattttc taaggaaatc agagcaaaga tggtgacctt caaattcatg
    43201 gaggatagag gcggtcagct gaagattcac tcaactatct ccaagaaagc gcgcggggcc
    43261 tttctaacag ctttaataga aaatcaagta caaactgtgg gggaagcacg tcgcttgaac
    43321 tttgctggat ttgtttaccg agaagatttg tcacaaccac agggattggt ttttgtaaag
    43381 gaagtataga aatcagataa gagaaaagtc agcacgatta tgctgacttt tttgataact
    43441 tataaagtat tggacaaatg aatctcattt gataaggtgt taagatgatt aaccaaattc
    43501 atgattgaca gatgatttcg gcaaataaac ttcttggtaa tccctggaat atagaaatta
    43561 gacacgatga tatcgtaatc tgtctgattt aaaatctcag gacttgtttt taattcatcc
    43621 caaatatcga aggtaaagcg gttattacag taataggaaa gcatatcaac aaaggtaagg
    43681 gatatagcat ggtcaaagtt actgataatc aaaaccttga taggtggtcg attttctaac
    43741 aactgagtag agaggttttc agcatgggtt aagatggtgt acatcaagtg ttccaactgt
    43801 tcaggatggt catgctgtcc aattgcctga cggtattgag ccagttcttg acgcgcactt
    43861 cccataaagt ctgggaagta aacttcaaat tttttaatcg tcaatgcttt ttgttcaaat
    43921 aagattgggg tagaaaagat ttcttgtctt tcaaagaaag cagtgttgtg taaatgccaa
    43981 atcagctcat cgtggttagt aaaagtaatc ttatattgtt ttgataggcg ttctaatatt
    44041 tgactaagta attggtaaga gtatcttgct tgactgttat cttctaaaga gttgaagaat
    44101 tcttgaggat ctaggaaaat atcattctga agaaaagaaa taaaaatttg agcgattgta
    44161 tctggagtca tttcaagccc aaaatgttta gagaaataag caagtgtctc ctggaaattt
    44221 ggaatgctct ttaaaagagg ataatattct ttgtaaaagt ggttggggag gtcaatgaag
    44281 tgaccatttt taaccctgtg gatactaata gctatcatca gtttgtacat tctataaatt
    44341 gaaaatcgca ttggataatt cgtgatttta tagaagaagt cagcaaactc tgttaaatct
    44401 tcctcaggaa ggtcaggaaa aggccaatct aggaaataat agcgctcaga aaagtattgg
    44461 gcaaaaaagt aacgaatatc gatctcattt ccacgtatct cggatggagt aaaagataat
    44521 tcaatttgaa actgagatga aagaaccttt gtaatatttc tgcccagtcg atagaggttg
    44581 gcactactaa agtaaagatt ttctattgtt cgataaatag gtagcccctc attgaagaac
    44641 atatactcta gtaattgaaa agattgagaa ttagcaagaa aatattgata aatatcttct
    44701 acactagtgt taacttctaa atctatcatg attccgttaa cagaagattg gatgttaata
    44761 gatggaaagg caatacgtaa ttcatttaaa tcacttttta agattcgttc tgtacatcct
    44821 aatttttcgg ctagttcatg taatttcatc caattacgat tctgaattag ggtttccatt
    44881 aagcgtaatt gtctttgaac ttttgtggat aaaaggtttc tcatacgggt atttcctcca
    44941 taattcatta tatctttttt tgtctaagta gtataaaaaa attagagcaa gaaaattgtc
    45001 gttagtaatc ggaaaaatta gaataatata agtggctttt aagtgcagaa acagagtata
    45061 ttaattgttc agaaaatatt gattaatgcc tcaaatagtt gtacattgta aactataaaa
    45121 tactatctag gagtttaaaa tgaaacattc acataaaaaa tcatttgact ggtatagcat
    45181 gcaacaacgt tattctattc gtaagtatta ctttggtgca gctagtgtct tgctcggtac
    45241 cgctttggta ttaggtgtag cagctagtgt ccaaacagta caagcggaag aaaacaaaca
    45301 agaaactacc aatagtattt ctgttggtag gggagaagca gctactaaac cagcagaggt
    45361 ttctgcgtct aataaagaga aaacctatgc agctccaact gtagctaatc cagtagaaac
    45421 gactccagtt aaaactgaag aagttactaa accagcagaa aaagttgaag aagcaaaaga
    45481 caaaaaagag gaagtaacgc atcaagatgc cgttgacaag tcaaaattat taacggctct
    45541 ttcgcgtgct aaaaaattag aaagcaagtt atatacagaa gcaagtgctg ctaacttgca
    45601 aacaagtatc caagctggtc aaagcttgct tggaaaagca gatgcaactg aagctgaatt
    45661 atcagcagca gagtcatcta ttcaatcatt tattattggt ctagaacttc gttctaactc
    45721 taataaagaa actgtatcag aaacgcctgt agcgaagaaa gctgatgcag ttgaatcaaa
    45781 agaaggggct aaaccagctg caacaactga acgttcagct gttgatagcg ctattttgcc
    45841 aactagcaca gctgacaaag tagaaacaac ttcagctcca gcatctatta atgaaatctt
    45901 gaaactaggt ttgagccttt ctgatgctcg ccaaaatcca gctatccgta aggaaaatgt
    45961 taatagaggg tatagtggtt ttagagcggc tagcaatcca gccaacccaa ttgtctcagg
    46021 ttctggaaat acagttgcat ttgcagatat tagccaaggt ggtcgtagct atagtttccg
    46081 tggctacggg aactcacgtg gtggaaattc tattcattac gatgtaacaa cagtacgtag
    46141 tggtaatagt gttaacttta caattagtta ttctgcgcca ggagattcta gagagtttgt
    46201 taataataat tttatcttgg ataaagggga tggatttgga aatccttcaa atgcaacgat
    46261 cacaagttca aatccaagag taagggagca atcaaaatct attagtcagg gtgccaacta
    46321 cgtatctcac tcaggataca gtatgacctc tgctatttca acaaatacgg aacaaactat
    46381 cagatttagt ttgcctatca ttaatctaaa tggtgatttg tctgttcgtt tgaaacctgt
    46441 tacttttaac gtggaccaag gtggtggtgg tgccgctact agcaatgacc catacagtaa
    46501 ctctaactat tattatagag caaacccact atacttggat gcaaaccctt atggtggtac
    46561 taataataag actgtttcag aagacattga cttccaaact gtctatcttc caactagtaa
    46621 gttaccagaa ggtcaaacta gattagttcg agaaggtgaa aaaggacaac gtcaaattac
    46681 ctataaagtt catcgatttg gtaacgaaac acttttagga ttgccgatta gtaatagtgt
    46741 tactaaagaa gctaagccac gtattatgca aattggtgtg gctaaagatc taatcgatac
    46801 agtaaaacca cgtgttgatc aaaataaagt cggtgataca aataacctca ctttctatct
    46861 tgataacgat ggaaacggtg tttatactga aggtgtagac gaacttgttc aaaaaattgc
    46921 tattaaagat ggagctaaag gtgaaaaagg agaccaaggt gaacgcggtc taactggagc
    46981 taaaggtgaa aaaggagacc gaggcgaacg cggtctaact ggagctcaag gagctaaagg
    47041 tgaaaaagga gaccgaggcg aacgcggtct aactggagct caaggagcta aaggtgaaaa
    47101 aggagcccaa ggtgaacgcg gtttaactgg agctaaaggt gaaaaagggg accaaggtga
    47161 acgcggtctc actggagccc aaggtgaaaa aggagaccga ggcgaacgtg gtttaactgg
    47221 agctaaaggt gaaaaaggag cccaaggtca ggcaggtcgt gacggtgtaa ctccaaccgt
    47281 aaccgttaaa gataataaaa atgacggcac tcatactatc actattaacg acggtagagg
    47341 taatgttaca agtactgttg taagagatgg tttcgatggc gcaagtccat tagttgcgac
    47401 tcaacgaaat gacgcagata agacaacaac tgttatcttc tattacgata aaaatggaaa
    47461 caatgaatta gatgcttctg ataagaaatt aaaagaagtt gtaattgcag atggtgctaa
    47521 aggtgaaaaa ggggacaaag gtgaacaagg tcttcaaggg cgtgatggtg aacaaggacc
    47581 aaaaggagaa gatgggaaaa ccccaacagt taaagtaact gatggtcaag atggaacgca
    47641 tacaattaca attaacgatg gtaaaggtgg tataactact acagtagtaa gagatggatt
    47701 tgatggtgca agccctcttg tttctactca tagaaatgaa gcagataaaa caacaactgt
    47761 tattttctat tatgatctaa atgataataa tcaatttgat gaaggagata caaaacttaa
    47821 agaagttgtt atcgcagatg gaaaacaagg accaaaaggt gacaaaggtg ataacggaaa
    47881 agatggattc acaccagaag taacagttac agataacaat aacggaacac acaccatcac
    47941 aatcacacaa ccagacaaca gaccatcatt aacaacaatc gttaaaaacg gtgaagatgg
    48001 aaaaacacca aaagtcaaag cagaacgaga tgatgcgaag aaacaaacaa cattaacatt
    48061 ctacattgac aaagatggag atggaagtta cacagcagga aaagacgagt tagttcaaac
    48121 aacagtagtt aaagacggac aagacggagc tgcaggagca tctggacgtg atggaaaaga
    48181 agtattaaac ggaaaagtag acccaacaac agaaggtaaa gatggagaca cattcgtaaa
    48241 tacacaaaca ggagatgtat tcgttaagaa aggtaacact tgggaaccag caggaaacat
    48301 caaaggaccg aaaggtgaca aaggtgcaga tggtgccaag ggtgaaaaag gagcccaagg
    48361 agaacgcggc ctgactggag cgcaaggtgt caagggtgaa aagggagatc agggtgaacg
    48421 cggtctaact ggatctaaag gtgaaaaagg agaccaaggt gaacgcggtt taactggagc
    48481 gcaaggtgcc aaaggtgaca aaggtgaaca aggtcttcaa ggtcgtgatg gagctcaagg
    48541 accaaaaggc gcagatggac aaagaggacc agcgggacca caaggaccaa aaggagaaca
    48601 aggtaatcca ggaactccag gtaaagatgg aaaatctcta attgctgtta aaaatggaac
    48661 tgaaacaaaa gtctatgtag aggatccggc tagaccagga caaccactta atccaaacca
    48721 accattagca actatcactg atggaagaaa cggtactaat ggacaatcac caacaattac
    48781 agcgacacga agtgtgcaaa atggcaaaaa tggtgtatta gtaacaatta caccagtagg
    48841 aggtcgtcca caaacaacat ttgtagagga tggacaaaag ggtgctgatg ggaaaacccc
    48901 aacagtaaca ataactgagg ggcaaaacgg cacacataca ttaacggttc ataatccagg
    48961 aagtccagat gtgacaacta cgatccgtga tggagctaca ggacaagcag gtcgtgatgg
    49021 taaagatgta ttaaacggaa aagtaaatcc acaaccaaac caaggtaaaa atggagataa
    49081 atatattaat accgaaaccg gtgatgtcta tgttaaaaac aatggaaact gggataaaga
    49141 aggcaacatc aaaggcccta aaggggacaa aggtgcagat ggtgctaaag gcgaaaaagg
    49201 agaccaaggc gaacgcggcc taactggagc gcaaggagct aaaggtgcgg atggcgcagt
    49261 aggtcgtgat ggacgtgacg gtaaagacgt gttgaacggc aaagctaacc cagaagcaca
    49321 tcaaggtaaa gacggcgata aatacgttaa tacagaaaca ggcgacgtct tcgttaagaa
    49381 taacggcaac tgggataaag agggcaacat caaaggccct aagggtgaca aaggtgaacg
    49441 cggagaagat ggtaagactc cagaagtaac tgtaactcca ggtaaagatg gccatagtac
    49501 tgacattaca ttcactgttc caggtaaaga tccagttaca gtaaatgtta aggacggaga
    49561 aaatggtctg aacggtaaaa ctccaaaagt tgatttactt cgtgtccaag gaaaaaacgg
    49621 aaatccatct catacaattg tgacattcta tacagatgaa aacaatgacg gcaaatatac
    49681 accaggaact gatgaacttc taggttcaga aatgattaaa gatggtgcta aaggcgcgga
    49741 cggacgagat ggtaaatcat tgcttactgt caaggatggt aaagaaacta aagtttacca
    49801 agaagatcca gctaacccag gacaaccatt aaatccagaa aaaccacttg cggtaattag
    49861 agatggagta gatggaaaat cacctacagt tacagctgtt cgtaaagatg aagcagggca
    49921 taaaggtgta gaaatcactg ttgataacca tgatggttca caaccaacta cagtctttgt
    49981 tcaagatggt gctaagggag aaactggtgc aaccggtcag gatggacaaa ctcctacaat
    50041 cactactcaa cgtggacaag atggccaaag cactgttgta actatcacaa catcaggtaa
    50101 agatccagta accttcactg taaaagatgg taagaatggt aaagatggcc gtgcaccgaa
    50161 aatcaaagta gaagatatta cttcaccttc aagaattaga cgcgatacag atgctgctgc
    50221 aactccaacg cgtaacggta tccgtgttac agtttatgat gatgttaatg acaatggggt
    50281 atacgacgaa ggtgtcgata aagtattaaa tagtaaagat atttataacg gtatagatgg
    50341 acgtgatggt tcagctccaa ctattactac aaaagataat ggagatggaa ctcacactat
    50401 cacagttcaa aacccagatg gttctgaatc aacaacagtt gttaaagatg gtaaagacgg
    50461 taaaactgcg aatatcacta caacagaaaa cccagatgga agccacacaa ttacggtgac
    50521 aaatccagat ggttcaacta aagaaactgt tgttaaaaac ggtaaagacg gtaagactcc
    50581 taaagttgaa gtaacggata acaacgatgg aactcatact gttaaagtta cagatggaga
    50641 cggcaatgtt accaacgcta tcatcaaaga tggtaaagac ggtaaagctg caacagcaac
    50701 aactactgaa aatccagatg gaagccacac agtaacaatc actaacccag acggaactaa
    50761 gaatgagttt gttgttaaga atggacgtga cggtgttgac ggacgtactc caaccgcatc
    50821 tgttcgtgat aatggagacg gaagtcatac aatcgttatt acaaatccag aaggtgtgac
    50881 aactgaaacc acagttcgtg atggtaaatc accaaaagtg actataactg atgaacaaaa
    50941 tggaactcat aagatctctg ttctaaatgg tgacggaaca actacaacaa ctacagttcg
    51001 tgatggtaga gaaccaaaac ttgaagttat tgataacaac gatggttcac acactattaa
    51061 agtgacaggt gctgatggta aaggaacgac aactacaatc tttgatggta aatcaccaaa
    51121 agcgaacatc gttgataacg gagatggaac tcatacatta acaatcgtag attctgatgg
    51181 tcgtgaatac aaatctatta tcaaagatgg taaagacggc aaagatagcg tttcaccaac
    51241 tgtaactgtt aaaaataata acgatggaac tcacgttgtt acaatcacta atccagatgg
    51301 aagtaagaca gaaatggtga ttaaagacgg taaagatggt aaatcaccaa aagtttctgt
    51361 tgaagataat ggtgatggta gtcatacaat cacaatcatc aattctgatg gaactgtgac
    51421 aaaaacagtt attaaagatg gtagagatgg acgtgatggt cgagacggca aagacggtaa
    51481 agacggtaaa gatggaaaat gtggatgcca agacaaacca gtaacaccat caaatgacaa
    51541 accagttcct ccaacaccaa atgtgccgac accagaagta ccggttaaac ctgtgccagc
    51601 gcaaccaaca ccaaatgtac cgacaccaga agtgccagta caaccaactc cagctgttcc
    51661 aacaccagaa gtaccggtta aaccagtacc agcggttcca gaacaaccag tagtaccaac
    51721 accggctcaa ccagcaactc cagtaaatgc taacccagta gcaccaacta caggtaaaga
    51781 aaaccgtggg gacaaattac ctgaaactgg aagccaatct gattatatct ctgttctttt
    51841 aggtagcggt attctattga gcctatatgt aggacgaaga aaagaagctt aatcagccaa
    51901 aagcagtcac taatttctcg aaagaagatg ataagtgata gatctcgaat gaaagaatat
    51961 tcttagaatg attttcctat gatggaaaag actgctaaaa accttgagtg gtaacgctca
    52021 aggttttttt ggatggctga tgtttgtctg aaaatcttga ttgagaaata aaaagccacc
    52081 ctattaggtg gctataattg atttagactt tctaaaattt tctatttttt actgaatcgc
    52141 ttcgaccaag tcttgagctt gtttttcaag tgagtttagg actgtttctt caagaaccaa
    52201 ttttccgtct gcccaggcag agtcattaac acgtgcagca gtgaaatcac caacgccttg
    52261 tgtacggata aatggcaaga ggtctttgta gatagcgaaa agttgatcgt gccctgcatt
    52321 ggctacagat gatacggtga caaacttgtc ttgaagggca gaaacgccac gcgtatcaga
    52381 caagtcaagg gcacgagata gccagtcaag caagtttttt actgtaccag ggatagagaa
    52441 gttgtagact ggagagaaaa tccagatagc atccgcaacg agaactgctt cacgagcagc
    52501 agctacagct ggatgtgttg gaacttccaa atcttggctg aagagaggaa gggctgaata
    52561 atcaaggtag ctaacttccg ctttaccagc aagtgctttc tcagcttcga gcgccatttg
    52621 gtggttgaaa gaaccttgac gtagtgatcc gacgataaat aatacttttt tagacatgat
    52681 gtgtctcctt tttcttcaaa ttttgagaac tctctcgttg ttataaaata cattacaaca
    52741 aaacaaaaga acttgcaaga aatttgctca gagtttattt gaaaattgta aaatttcgga
    52801 aactctagtc atttgtgact gaaaaagtaa gaactgtttc actttcaaaa tcggttttgt
    52861 ttgaagggag aaatagaatt ggttgctcaa agcacagctt tgaggttgca gataaagctg
    52921 acgtggtttg aagagatttt cgaagagtat tcttatattc acttgtaata aagcttaata
    52981 gatggtaaaa tagacgagtg aaaaaaagac aaaacaaagc aaaaaataat ctactgtggc
    53041 agtatggtct agggatgacg attttgtttg tggttatcag tgcttccttt ctgtatatgg
    53101 tttctcttag catgaaaccc tatcaaacag ctaaaagtga aggagaaaaa ttagctcagc
    53161 agtatgcagg attagagcag gccgatcagg ttgatttata caatggcttg gaatcttatt
    53221 acagcgttct tggtcgtaat aaacagcaag aagcacttgc tgttctgatt ggaaaagatg
    53281 atcataagat ttacgtttat cagctaaatc agggtgtttc acaagaaaaa gcagaaacgg
    53341 tttctaagga aaagggagct ggcgaaattg acaagattat ctttggtcgt tatcaagata
    53401 agccaatctg ggaagtcaag tcaggatctg atttttatct agtagatttt gaaacaggag
    53461 cattggtcaa caaggagggc ctatgaaatt atccaaccgt gttttagaaa tggaagaaag
    53521 tgtgactttg gctgctggag cccgtgccaa agcactgaag gctgagggta gagatatttt
    53581 gtctctaacc ttgggtgagc cagatttcac tactcccaaa aatatccaag atgccgccat
    53641 tgcatcgatt cgagatgggc gtgcttcttt ttatacagta acctcaggtc tgccagagct
    53701 taaggcggcg gtcaatagct actttgagcg cttttacggc tattctgtag cgtcaaatca
    53761 agtgacagtc gctgcgggag ccaaatattc tctctatacc ttctttatgg ctgtggtcaa
    53821 tccaggtgat gaagtcatca tcccaacccc atactgggtt agctatggag atcaggtcaa
    53881 gatggcagaa ggcgttcccg tctttgtttc tgctaaggaa gacaatcact ttaaggtgac
    53941 cgtagagcag ttagaagcag ctcgcactga caagaccaag gttttggtgc tgaattcgcc
    54001 atctaatccc acaggtatga tttacacccg tgaggaactc ttggcaattg gaaactgggc
    54061 tgtagaaaat gatattctca tcctagcaga cgatatctat ggccgcttgg tttataatgg
    54121 tcatgagttc acaccgattt ctagcctatc ggaagcgatt cgcaagcaaa cagtggtcat
    54181 caatggtgtg tctaaaacct atgccatgac tggttggcgg attggttatg ccgttggaga
    54241 agcagacatt atcgctgcca tgtccaagat tgcaggtcaa acaacttcga atccgtcagc
    54301 agtagcccaa tatgcagcag ttgaggctct atcaggtgag caagatactg tagaaagcat
    54361 gcgtcaggcc tttgaggaac gtcttaatac catctatccc ctccttgcag aggtgccagg
    54421 atttgaagtg gtcaaaccgc aaggggcctt ctatctcttc ccaaatgtca aaaaggccat
    54481 ggagatgaaa ggctacacgg atgtgacaga ctttacaact gctatcttag aagaagccga
    54541 agtggccttg gtaacaggag ctggatttgg agcaccagaa aatgtccgcc tcagctatgc
    54601 gacagaccta gacacgctta aagaagcagt cgaacgcttg aaagcattta tgggtagtga
    54661 gaatgattga tcattttgag attaaggtaa aggatttaca aatttcagaa ggattttata
    54721 ggagttttct cgctcctttg gactataaat tggcttttaa gactagttct ctaattagtt
    54781 ttctatcccc gaacagccct catcctggtg gtgatttttg gctgactcag ggaacacaag
    54841 atcctgttca ttttgctttt ttagcagaaa ataaggaaga agtttaggct tgttatgagg
    54901 ctggcttaga ggcaggtggg cgagataatg gggctcctgg ttatcgaagt gagcgtccga
    54961 tttactatgc tgcttttatg attgacctgg atgggaacaa tatagaggtg gtttgccata
    55021 aagaataaaa aagaaaagga aaaataatga caaaacgtgt aacgattatt gacgtaaaag
    55081 actatgttgg tcaggaagtg acgattggcg cttgggttgc caataaatca ggaaaaggga
    55141 aaatcgcttt cttacaattg cgtgatggaa cagccttctt tcaaggtgtg gcttttaaac
    55201 caaactttgt cgaaaaattt ggtgaagaag tgggacttga gaagtttgat gttatcaaac
    55261 gcttgagcca agaaacgtct gtttatgtga caggtattgt caaagaggac gaacgttcta
    55321 aatttggcta tgagttggac atcacagaca tcgaagtgat cggtgaatct caagactacc
    55381 caatcacacc aaaagaacac ggaacagact ttttgatgga taaccgtcac ttgtggctac
    55441 gctctcgtaa gcaagtagct gtgttgcaaa tccgtaacgc tattatctat gcaacttatg
    55501 agttctttga caagaacggt tttatgaagt ttgacagccc aattctttca ggaaatgcgg
    55561 cagaagattc tacagaactc tttgaaactg actacttcgg aacgccagcc tacttgagcc
    55621 aatcaggtca gctttaccta gaagcagggg ctatggctct tggtcgtgtc tttgactttg
    55681 gtccagtttt ccgtgctgaa aaatcaaaaa cacgccgtca cttgactgag ttctggatga
    55741 tggatgctga gtactcatac ttgacacatg atgagtcgct tgacttgcaa gaagcttatg
    55801 tgaaagctct tctacaaggt gttcttgacc gcgcgcctca agccttggaa accttggaac
    55861 gtgatacaga actcttgaaa cgctacattg cagagccatt caaacgtatc acttacgatc
    55921 aagccattga cctcttgcaa gagcatgaaa atgatgaaga tgctgactac gagcatcttg
    55981 agcatggtga tgactttggg tcaccacacg aaacttggat ttcaaaccac tttggtgtgc
    56041 caacatttgt catgaactat ccagtagcca tcaaggcctt ctacatgaaa ccagttcctg
    56101 gaaatccaga gcgcgtgctt tgtgcagact tgcttgctcc agaaggctat ggagaaatta
    56161 tcggtgggtc tatgcgtgag gaagattacg atgcccttgt cgctaagatg gatgaacttg
    56221 gcatggatcg tacagaatat gaattctacc ttgaccttcg taaatacggt acagttccac
    56281 acggaggatt tggtatcggt atcgaacgta tggtaacctt tgcagcagga acaaaacata
    56341 tccgtgaagc tattccattc ccacgtatgt tgcaccgtat caaaccataa gaacaggaaa
    56401 acgcccatgt ggcgtttttt cgaattctag tgtttttact tgcgtaaaaa aattttttct
    56461 agtataatag tttattgtga gcgaacctca cttacccctt gcaaagtctt ggggtcatta
    56521 gaccaaaagg aggaacatat caatggctaa atacgaaatt ctttatatca ttcgtccaaa
    56581 cattgaagaa gaagctaaaa acgctttggt agcacgtttt gactctattt tgactgacaa
    56641 cggtgcaact gttgttgaat caaaaacttg ggaaaaacgt cgtcttgcat acgaaatcca
    56701 agatttccgt gaaggacttt accacatcgt taacgttgaa gcaaatgacg atgcagctct
    56761 taaagagttt gaccgtcttt caaaaatcaa cgctgacatt cttcgtcaca tgatcgtcaa
    56821 aattgacgcg taagaaggta aactatgatt aacaatgttg tacttgtagg gcgtatgaca
    56881 cgtgacgctg agttgcgtta taccccatca aatgtagcag ttgcgacttt tactcttgca
    56941 gtaaaccgta catttaagag tcaaaatggt gaacgtgagg ctgattttat caatgtcgtt
    57001 atgtggcgcc aacaggctga aaatcttgct aactgggcta aaaaaggctc acttatcggg
    57061 gtgacaggtc gtatccagac tcgtagttac gataaccagc aaggacaacg tgtctacgtg
    57121 acagaggtcg tggctgagaa tttccaaatg ttggaaagcc gtagtgtgcg tgagggtcac
    57181 acaggtggag cttactctgc accaactgca aactattcag cacctacaaa ttcagtacta
    57241 gacttttcac gtaatgaaaa tccatttgga gcaacaaacc cattggatat ttcagatgat
    57301 gatttaccat tctaatggac aactaaactt ataaaggaga aaaaacatgg ctcaacaacg
    57361 tcgtggcgga ttcaaacgcc gtaaaaaagt tgattacatc gcagcaaaca aaattgaata
    57421 tgttgattac aaagatactg agcttcttag ccgtttcgtt tcagaacgtg ggaaaatcct
    57481 tcctcgtcgt gtaacaggaa cttcagctaa aaaccaacgt aaagtaacaa cagctatcaa
    57541 acgcgctcgc gtaatggctt tgatgccttt cgtaaacgaa gattaaagaa aagacccggt
    57601 tgggtctctt tttcatgagc ttgaaaacaa gaaagcgaat taagacccca atgggtcttt
    57661 tttcacaaac tttgaaatga gagagcgagt taggctcagt ggctcccttt ttacgagttt
    57721 gaaaacaaga gaacacatta aaagcacgat ggagcttttt cataaatatg tcttttttct
    57781 catccaagaa attaaaataa aaatgataaa ctttttgaaa ataggggatt tgcctacttt
    57841 atgatataat ggaaagagtt agattgaaag aggtagtgag atggacgcga aattaagata
    57901 caaggcaaag aagatcaaga ttgtcttttt tgatattgat gatacattgc ggaattcaaa
    57961 gacagggttt attccaacta caattcccac tgtttttaaa cagttgcgtg aaaaaggaat
    58021 tttaacagga atcgcctctg gacgtggcat ttttggtgtt gttccagaga ttcgtgatct
    58081 caagcctgac ttttttgtaa ctttgaatgg ggcttatatc gaagataaaa aaggtcaggt
    58141 catttatcag catcagattg aaaagtcaga tgttgaggag tatatctctt gggctaagca
    58201 agaaggaatt gagtatggct tggttgggag tcatgatgcc aagttgtcga ctcgcaccga
    58261 tatgatgagt gaagctatca atccaattta tcccgactta gatgtagatc ccgatttcca
    58321 tgaaaaagaa gatatctatc agatgtggac ttttgaagat aagggagatg acttgcactt
    58381 gcctgacagt ctctcagaca aacttcgcat ggttcgttgg catcaacatt cgtctgatat
    58441 tgtgccgatt tcaggctcca aagcgacggg ggtggaaaaa gttgtggaac accttggctt
    58501 gaaaccagag aaggtcatgg tttttggaga tggtctcaac gacttggaac tctttgatta
    58561 tgctggaatc agcgttgcca tgggaatttc tcatgataaa atcaaagaaa aagcagatta
    58621 tattacaaaa acattagaag aagatggcat ttttgatgcc ttagaagtat ttggtatggt
    58681 agaaaaagaa ttgcattttc cacaagtaga cattgaaaca gtagaaggtc ctcttgcgac
    58741 tattaagacc aatcacggag acttacgtat caagcttttc cctgaacatg ctcctaaaac
    58801 agtggctaac tttgtatctc tttcaaaaga tggctactat gatggtgtca ttttccaccg
    58861 tattatcaag gactttatga tccaaggtgg aaacccaact ggaactggta tgggtggcga
    58921 gtcaatctac ggcgaatctt ttgaggatga attctcagaa gagctttaca atatccgtgg
    58981 tgctctttcc atggcaaatg ctggtccaaa taccaacggc agccagttct ttatcgtgca
    59041 aaaccaacac ctaccttatt ctaagaaaga aattactcgt ggtggttggc cagaaccgat
    59101 tgcagaaatc tatgccaatc aaggtgggac acctcaccta gaccgtcgtc acacggtttt
    59161 tggtcagtta gctgatgaag catcttacgc tgtcttggat gccattgctg ctgttgagac
    59221 aggagctatg gacaagccag ttgaagatgt tgtaattgaa actattgaaa tcgaggacta
    59281 agatgaaaat cggtgataag ctaaaggggc gtattacagg gattcagccc tacggtgcct
    59341 ttgttgagtt agagacgggt gatacggggc tgattcacat ttcagaaatt cggacaggat
    59401 ttattgaaaa tattcatgaa accttgaaag tcgatgaaga ggttcaagtt caggtagtgg
    59461 atttagatga atttacgggg aaagccagtc tttctatccg cactttggag gaagaaaagt
    59521 accagtttcc tagacggaga cgcttttcaa gcgaccgctt taactacggt tttgctccct
    59581 ttcgacgaat gctaccaatc tggactggag aagccctgca ccatttaaaa aagaagaagt
    59641 agtttagagt tttatatttt ttgtaatgtt aatataaatt tgctataata ggaccatgga
    59701 agaagaacaa ttattaaaat caggagagcg cattaaccag ctcttttcga cagatatcaa
    59761 aatcattcaa aatagagagg tttttagcta ttcggtggat agtgttctct tatcacgatt
    59821 tccacgtttt cctaagaagg ggttgattgt ggatttctgt gctgggaatg gagcagtggg
    59881 gctttttgct agcactcgta ctcaagcaca gatattgtct gttgagattc aggagcgttt
    59941 ggcggatatg gctgaacgct ctgtccgttt gaatggatta gaggagcaaa tgcaggtcat
    60001 ctgcgatgat ttgaaaaata tgcctgctca cattcagggg agtaaggtgg atatgatttt
    60061 gtgtaatcca ccctatttca aggtggatcc ttattctaat ctgaacgaga gtgaacatta
    60121 tctcttggct cgacacgaaa tcacgactaa tttggaagaa atctgtcata gtgcccagag
    60181 tattctcaag tctaatgggc gtttggccat ggttcatcgt cctgatcgac ttctggatat
    60241 tttggatacg ttaaaacgac ataatctagc ccctaagcgc ctgcagtttg tttatccaaa
    60301 aagagaaaag gaagccaata tgcttttgat tgaggcgatc aaggatggct caacaagtgg
    60361 ctttaaggtc ttacctcctt tgattgtcca caatgatgat ggctcttata cgcccgaaat
    60421 cgaagagatt tattatggat cataaggctt atatgtacgt tctggagtgt cgtgatggat
    60481 cctactatat aggctatacg actgatatga gaagacgcct cgctatccac aatagtggga
    60541 agggagccaa atatacacga gcacgcttgc cagtcaaact tatctatgct caaggttttg
    60601 tcagtaagga agaagccatg tcggctgaag ctcttctcaa gcgtaagaag aggccacaga
    60661 aggaagaatt tttatctgaa aatcaagata gaaatttact cagttatttt gaagaatcgt
    60721 ggggagtcct ttgactcctc ttacctttgt caaaaagcga aaaaaatgct acaataaaga
    60781 aaataaacaa aatgaggtat tatcatgtcc aagattctag tatttggtca ccaaaatcca
    60841 gactcagatg ccatcggatc atctgtagct tttgcctacc ttgcaaaaga agcttacggt
    60901 ttggatacgg aagctgttgc ccttggaact ccaaatgaag aaacagcctt tgtcttgaac
    60961 tattttggtg tggaagcacc acgtgttatc acttctgcca aagcagaggg ggcagagcaa
    61021 gttatcttga ctgaccacaa tgaattccaa caatctgtat cagatatcgc tgaagtagaa
    61081 gtttacggtg ttgtagacca ccaccgtgtg gctaactttg aaactgcaag cccactttac
    61141 atgcgtttgg agccagttgg atcagcgtct tcaatcgttt accgtatgtt caaagaacat
    61201 ggtgtagctg tgcctaaaga gattgcaggt ttgatgcttt caggtttgat ttcagatacc
    61261 cttcttttga aatcaccaac aacacaccca acagataaaa tcattgctcc tgaattggct
    61321 gaattggctg gtgtgaactt ggaagaatat ggtttggcaa tgttgaaagc tggtaccaac
    61381 ttggctagca aatctgctga agaattgatt gacatcgatg ctaagacttt tgaactcaac
    61441 ggaaataatg tccgtgttgc ccaagtgaac acagttgaca tcgctgaagt tttggaacgc
    61501 caagcagaaa ttgaagctgc aatgcaagct gccaacgaat caaacggcta ctctgacttt
    61561 gtcttgatga ttacagatat cgtcaactca aactcagaaa tattggctct tggtgccaat
    61621 atggacaagg tcgaagcggc tttcaatttc aaacttgaaa acaatcatgc cttccttgct
    61681 ggtgccgttt cacgtaagaa acaagtggta cctcaattaa ctgaaagctt taatgcgtaa
    61741 gattttgggt gtcagctcaa aatcggaaag tctagtttgc cttatatcga aaggagtttc
    61801 ggctcctttt tttctaggag tgaagtatgt tagaaaatgg cgatttgatt tttgtgagag
    61861 atgggtcaga catgggacag gccatccaga cttccacagg taactatagc catgttgcca
    61921 tttatttgga tgggatgatt tatcatgcta gtggacaggc tggtgttgtc tgtcaagaac
    61981 cggcagactt ctttgagtcc aatcatttgt acgacctcta tgtttaccca gaaatggata
    62041 tccagtcggt gaaggaaaga gcttgcagac atcttggagc accctacaat gcttctttct
    62101 atccagatgc agctggtttc tactgctccc agtatatagc agaaatccta cctatttttg
    62161 aaactattcc tatgaaattt ggagatgagg aacaggagat tagtgatttt tggagggagt
    62221 attacataga actaggtctg cctgttcctc tgaaccaagc tgggaccaat cctagtcagt
    62281 tggcagcatc gcctctgtta caatgtaaag aaaggaatct tcatgattca gatttttaat
    62341 ccatctcgtt tgacgagaca gccatttttg gagaattgat ccgctatctg gaccagtatg
    62401 aggatgtgat tctacgggaa attaaggctc aatttccaga tgttgcagtt gataaactca
    62461 tggaagagta tataaaggca agcttgattc tacgtgaaaa taagcgctat taccttaatt
    62521 ttcctacgct tgaatcactt gatagtcttg aactggatca agagattttt gtcagagaag
    62581 ctagtccggt ctatcaagcc ttgttggagc agagttttga gacggaattg cgcaatcaaa
    62641 tcaatgcagc tattttagtt gaaaagacgg actttgcgcg cattaaaatg accctgtcca
    62701 attattttta caaggtcaaa cagcagtatc ctttgacaga aaaacagcag gagctctatg
    62761 acattttagg agatgttaat cctgagtatg ccctcaagta tatgacggct tttttgttga
    62821 aatttctcaa aaaagaccag cttatgcaga aatgccgtga tatctttgtg gacagtttgg
    62881 ttgtcttagg ctatattgtg caaaatgaag atggaaagta tgagttggct atcgattttg
    62941 ataaggagag attaactttc tacttagcgt gatttcttgt ttctgagtac attgtttgac
    63001 tttccttagt attcggtata aactatatgt aaccggtaac acatatcgga ataaactaaa
    63061 ggagacaatc atatgtcact tgaaaacaaa ttggaacaag caacaggcgc tgtcaaagaa
    63121 ggttttggta aagttactgg agacagcaag acagaacttg aaggagctgt tgaaaaaaca
    63181 gttgctaagg caaaagacgt tgtagaagac gcaaaaggtg ctgtagaagg tttgaaaaac
    63241 gtttttacta aataatagga aaaaatcaag ggtttcattt tcccttgatt ttttctattc
    63301 ttataaataa ttttctgcga cggctgtatc tcctgggtag gattctttct tgccctggat
    63361 gatttggtaa caatcgactc ccttacccgc aataataact gcatctaatt cgtgatttgt
    63421 gatagccatt gccgccttga tggcttcttg gcgatccgca atcttttcaa caggatgatt
    63481 gatgtagcta ctaatttcat ctgcaatggc cattgggtct tcatagttag ggtcatcagc
    63541 agtcagaaag acttgaatct cagggtgttg attgaggagg aggccaaagt ccttacgacg
    63601 actttctccc ttgtttcctg ttgatcccag aaccagagca atctttccgg tttgatgagt
    63661 ttccaccaca ttgatgagtt ttttcagact atccccattg tgggcatagt cgatgaagac
    63721 cttggctcca tttttctgag tgaggacttc catacgacca ggaacgcggg ttgcagcgat
    63781 gccttttttg atgtcctcaa gacttgctcc gagacggaga caagcaagtc cagcagcaac
    63841 tgcattttct tggttgaagt tgccaatgag ttggatatca taatctccag cgagtttacc
    63901 cgtagctgaa aagctaaagg ctttggaatt ctcgatttgg ttatcaaatt ggctaccata
    63961 gaaatcatgg tcttgatctt caacctgttc tttcaagact gagaagtggt ccatgtcact
    64021 gttaatgatg actgctcggc tattttccat caagagacgc ttgtggtaga aatagtcttc
    64081 aaagctaggg tgttcaatcg ggccgatatg gtctgggctg atattgagga aaactcccac
    64141 atcaaaggtt agaccataga cacgtttgac cagataggat tgactggaga cttccatgat
    64201 gaggtgggta cggtcatttt gcacagcctg attcatcatg tcaaagaggt caatactctc
    64261 aggggttgtc aacgctgact taaagaaagt ctcgccatca agagttgtgt tcatggtcga
    64321 caacatagca ggtctatgcc cttgagataa gatgttatag gcgaaatagg ttgctgttgt
    64381 cttaccctta gtaccagtaa aggcaaggag tttgagtttc tcttgtggat taccatagaa
    64441 ctccatggca atcaaactca tggctttctt tatatcgttc acaatgatga cagggatatc
    64501 gacttcgtag tccttttcag ctacatacca agctaaacct tgtgttatag cagaaagaag
    64561 gtattctttt ttaaaggcag cgccttttgc aaaaaaaaga gtgtcttctg ttacttttcg
    64621 gctgtcgtag ctgatgctat caaaaacaac tttgctgtag ttgtagtggt aatgaccttg
    64681 gtcaataatt tcgcgaaaaa ggccatcttt ctttaaaata tctaatacgg tttcaatctt
    64741 aatcatactt tctattgtaa accgaaagtc gcaaatttac aagtaacaag gaaaagttta
    64801 taatggaaga taaggagttt ttcctagtta tcaaaattga atgaggaatc tatgtcgcac
    64861 gaaaacaatc accagcaggc ccagatgtta cgggggactg cttggctaac ggctagtaac
    64921 tttatcagtc gcctactcgg ggctgtttac attatccctt ggtacatctg gatgggggct
    64981 tatgcagcta aggcaaatgg tctctttacc atgggttaca atatctatgc ttggttcttg
    65041 ttggtttcaa cagcggggat tccagttgcg gtggccaagc aagttgccaa gtataatacc
    65101 atgcgagaag aagagcatag ctttgccctg attcggagct tcttaggctt tatgacagga
    65161 ctaggcctgg tttttgcttt agtcttgtat gtctttgctc cttggctagc agacttgtct
    65221 ggcgtgggca aagacttgat cccaatcatg caaagcttgg cttggggagt cttgattttc
    65281 ccgtctatga gtgttatccg aggatttttc caagggatga ataacctcaa accctatgcc
    65341 atgagccaaa ttgctgagca ggtcattcgt gttatctgga tgctcctagc aacctttatc
    65401 attatgaagc tcggttcagg agattatcta gcagccgtta cccaatcaac ctttgctgcc
    65461 tttgtcggta tggtagccag ttttgcagtc ttgatttatt tccttgccca agaaggttca
    65521 ctcaaaagag tctttgaaac aggagataag attaacagta agcgtctctt ggttgatacc
    65581 attaaggaag ccattccttt tatcctgaca gggtctgcca tccagctctt ccagattttg
    65641 gatcagctga cctttatcaa tagtatgagc tggtttacca actacagcaa tgaggacttg
    65701 gttgtcatgt tttcttattt ctcagccaat cctaataaaa tcacgatgat tttgatttct
    65761 gtaggggttt cgattgggag tgttggtttg ccacttttga cggaaaacta tgtcaagggg
    65821 gacttgaaag cagcttctcg tctggttcag gacagtctca ccctactctt tatgttcttg
    65881 ctaccagcaa cggttggagt ggttatggta ggagaacctc tttatacggt cttctatggt
    65941 aagccagata gtttggctct gggcttattt gtctttgcag ttttgcagtc tattatttta
    66001 ggcttgtaca tggtcttgtc tccaatgctt caggccatgt tccgcaaccg caaggccgtt
    66061 ctctatttta tctatggttc tattgccaag ctagtcttgc aactacctac catcgccctc
    66121 ttccacagtt atggtccttt gatttcaaca accattgctc tcatcattcc taacgtcttg
    66181 atgtatcggg atatttgtaa agtaactggt gtcaagcgca aggtgatttt gaagcgaacc
    66241 attttaatca gtttgctgac cctagtcatg tttctgttaa taggaaccat ccagtggctg
    66301 ttaggatttt tcttccaacc aagtggacgt ttgtggagct tcttttatgt agctcttgtc
    66361 ggtgccatgg ggggtggact ttatatggtt atgagtctgc gtacctattt attagataag
    66421 gtaataggaa aagcccaagc agatcgcctg cgagcaaaat ttaagctttc gtaaggtagc
    66481 atttataaat aaaaggaata agttgaacaa tcttttagga gaacttgaaa cttattcctt
    66541 ttttagcgta aaaatagcta aaattatctt tcaaaaatag aaaatgaggt ttttttcgat
    66601 tttttggaaa aataattgac taaacaaacc aaacgttgta taataaaaca agtatttaaa
    66661 gcaggaggtt ctggaaatga aaaagtctaa gagcaaatat ctaaccttgg caggtcttgt
    66721 cctgggtaca ggagttttat tgagcgcgtg tggaaattct agcacggcgt caaaaaccta
    66781 caactatgtt tattcaagtg atccatctag cttgaactat ctagcagaaa accgcgcagc
    66841 aacatccgat attgttgcaa atttggtaga cgggttatta gaaaatgacc aatatgggaa
    66901 tattattcca tcattagcag aggattggac tgtttctcag gacggtttga cctataccta
    66961 caaacttcgt aaggatgcca agtggtttac ttctgaggga gaagaatatg cgcctgtaac
    67021 tgcccaggat tttgtgacag gtttgcaata tgcagctgat aaaaaatcag aagccttgta
    67081 tctagtgcag gactctgttg ctggtttgga tgactatatc actggtaaaa caagcgactt
    67141 ttcaactgtc ggtgtcaagg cacttgatga ccaaacggtt caatatactt tggttaaacc
    67201 agaactttac tggaattcaa aaacacttgc aacgatactt tttcctgtta atgcagattt
    67261 cctgaaatca aaaggggatg attttgggaa ggcggatcca tctagtattt tgtacaatgg
    67321 acctttcttg atgaaagcac ttgtctcaaa atctgctatt gaatataaga aaaaccctaa
    67381 ttactgggat gctaagaatg tctttgtaga cgatgtgaaa ttgacctact atgatggtag
    67441 cgatcaagaa tcactggaac gtaattttac agctggtgct tatactacgg ctcgtctttt
    67501 tcctaacagc tccagctatg aagggattaa agaaaaatac aaaaacaata tcatctatag
    67561 tatgcaaaat tcaacttcat atttctttaa ttttaaccta gataggaagt cttacaatta
    67621 tacttctaaa acaagtgaca ttgaaaagaa atcgactcag gaagcagttc tcaataaaaa
    67681 cttccgtcag gctatcaatt ttgcttttga cagaacatct tatggggctc agtctgaagg
    67741 gaaagaaggt gcaacaaaga ttttgcgtaa cctagtggtt cctccaaact ttgtcagtat
    67801 caagggaaaa gactttggtg aagttgtagc ctctaagatg gtcaactatg gtaaggaatg
    67861 gcaaggtatc aactttgcgg atggtcaaga cccttactac aatcctgaga aagccaaggc
    67921 taagtttgcg gaagctaaga aagaactcga agcaaagggt gttcaattcc caatccactt
    67981 ggataagact gtggaagtaa cagataaagt aggcatacaa ggagttagtt ctatcaaaca
    68041 atcaattgaa tctgttttag gttctgataa tgtagtgatt gacattcagc aattaacatc
    68101 agatgagttt gacagttcag gctactttgc tcaaacagct gctcagaaag actatgattt
    68161 atatcatggc ggttggggac ctgattatca agacccgtca acctatctcg atatttttaa
    68221 tactaatagt ggaggagttc tacaaaatct tggactagag cctggagaag ccaatgacaa
    68281 ggctaaggaa gttgggctgg atgtctatac tcaaatgttg gaagaagcta ataaagagca
    68341 agatccagcc aaacgttatg agaaatatgc tgatattcaa gcttggttga ttgatagttc
    68401 tttagttctt ccaagtgttt cgcgtggggg aacaccatca ttgagaagaa ccgtaccatt
    68461 tgctgctgcc tatggtttaa ccggtacaaa aggggttgaa tcatataaat acctcaaagt
    68521 acaagataag attgtcacaa cagacgaata tgcaaaagcc agagaaaaat ggttgaaaga
    68581 aaaagaagaa tccaataaaa aagcccaaga agaattggca aaacatgtca aataaaatct
    68641 aattgtagat aagtttgtgt aagaagtctt tgtgcttaaa aacgcataat atcaggtata
    68701 taaaatccta gatgttatgc gttttgttat aggaagattt attagatttt atcctcaaat
    68761 tgagttattc ccgactttat ccgttgaaat attataagga gtatttatga aattaaaatt
    68821 attaagagta gatactaagg tgattatggg gagtttcttc cttgttctgt ctagtctact
    68881 tgctttgttg cttcccctta tcttaaaagg tttaatagat gggagttcta ttgaaaatat
    68941 aggttccaaa gtatttcaat cgtttttgat ttttattggt caagccttgt tttcttctat
    69001 tggttactat ctgtttagtc aatcgggtga aaaaagatag caaaaatcag gaaaaaagtg
    69061 atagaggggt tgatttatgc agagaaatcc ttctttgata agagccaaag tggggagttg
    69121 acttctgcca ttgtcaatga cacgagtgtc attcgtgagt ttttaattac gactttccca
    69181 aatattattc tgagtttagt tatggtactt ggttccattg tagtcttatt tagtcttgat
    69241 tggaatcttt ctctactttt attcatcact cttccttgta tgatgtttat tatcttgccc
    69301 ctttccaata tcagtgaaaa gtatagtcgt cgtttacagg aggaaatcgg atttttaaca
    69361 gggcaattga ctgaaaagat tcaagaacat gaattaatta agactaacca agcagagaaa
    69421 agtgtacagg atgttttgga taattgtatt gaaagggtac aaaacaattc actgaaatca
    69481 gataggatta cttcttttga gaccccgttt gctctcttat ttatctttgc gactatagct
    69541 gtgatgctaa cctatggggg ttatcgggtc agcgcaggat atatatctgt gggaaccttg
    69601 gtttcgtttt tgatttacct ctttcaatta cttaatccta ttagtaatat agctaatttt
    69661 gtaactgttt attctaggag caagggatct tcagttgcac tggagaactt gcttgcagtt
    69721 cctaaagaaa aatttgaggg aggaaaatcg gtatcaggac gagggttgaa ttttaaccat
    69781 gtctattttg gttatgatga aaatcgacct gtcttaaagg atattatttg ttcaattttc
    69841 aaggggcaaa aaattgcttt tgttggacca tctggatcag gaaaatcaac gattgtgcgt
    69901 ttgttagagc ggttttataa accgctttca ggagatattc taatggagca atcaagtata
    69961 tatgatttta acttaaaaga atggagaagt aaaatcgctt gggtttcaca aaataatgca
    70021 gtcttatctg gcagtattcg tgacaatctt tgtctcggtt tgaatcgctt agtaactgat
    70081 gatgaattga tgaaagtgct agacttagta tcactaggtg atgagattcg ctccatgaaa
    70141 gagggactag atactgaagt tggtgaacgc ggacgactct tgtcaggggg gcaaagccaa
    70201 agacttcaaa tagctagagc ctacttaaaa gatgctgaaa ttcttatatt tgatgaagcc
    70261 actgctaatc ttgatgcgga ttctgagtat gcgattatca gtagcctcta ttctgtatta
    70321 aaggagaaga cggttgtgat tatagcgcat cgtttgtcaa cggtaaaaga tgtggattgt
    70381 attttcttct tagaggaggg gaaaatcact ggctcaggaa ctcataagga actactggaa
    70441 aatcatgagc gttatgctcg ttttgtgcag gagcaaatga tagagtgaag gtgtcttttg
    70501 agattcacca ttttatagtc tattaaaggg agcaggaaaa actccctttt tatatagttt
    70561 gaaactataa ctagctcttg aaaacaagaa aacgaaggat acaaaataag tggtacaata
    70621 gttactatag atttggagga attgtatgag caaggaatta cacattaaca caattttagc
    70681 acaagcaggg atcaagtctg atgaggcaac aggtgctttg gtgacaccac ttcatttttc
    70741 aacgacctat cagcatccag agtttggtcg atctactggg tttgactata cgcgcactaa
    70801 aaatccaact cgtagtaagg ctgaggaagt cttggcggct attgagtcag cagactatgc
    70861 cctagcgact agctcaggga tgtcagctat tgtactggcc tttagcgtct ttccagtagg
    70921 aagtaaggtc ttggcagtgc gtgatcttta cggtggttct tttcgctggt ttaaccaagt
    70981 ggagcaggaa ggtcatttcc attttaccta tgccaataca gaagaagagt tgattgccga
    71041 gttagaaaag gatgtggatg ttctctatat cgaaacccca accaatccct tgatgttgga
    71101 atttgatatc gaaaaactag caaaattggc tcatgctaag ggttccaaag tggtggtgga
    71161 caataccttc tatagcccta tttaccaacg tccgattgaa gatggagcag atatcgttct
    71221 ccattcagca accaagtatc tagcaggcca caatgatgtc ttggctggag tggttgtgac
    71281 caatagttta gaactatacg agaagctttt ttacaatctt aatacaacag gggcagtctt
    71341 gtctccattt gacagctacc agttgcttcg tggtctcaag accttgtctc ttcgtatgga
    71401 gcgctcaaca gctaacgccc aagaagtggt tgcctttttg aaggattctc cagcagttaa
    71461 ggaagttctc tacactggtc gtggaggcat gatttccttt aaagtagccg atgaaacacg
    71521 cattcctcat attttgaaca gtctcaaggt cttctctttt gcggaaagtt tgggcggagt
    71581 ggaaagtctt attacttatc caacgactca aactcatgct gatattccag cagaagtacg
    71641 ccattcttat ggtttgacag atgacctctt gcgtttgtct attgggattg aggatgctag
    71701 agatttgatt gcagatttgc gccaagcctt agaaggataa gacaaagatg ggaaaatatg
    71761 attttacaag cctgcccaac cgtttagggc accataccta taaatggaaa gaaacagaaa
    71821 cggatagtga agttctacca gcttggatag cggatatgga ctttgtggtc ttgcctgaaa
    71881 tccgccaagc cgtgcaaact tacgcagacc aactggttta tggttatacc tatgccagtg
    71941 aagacttaat taaggaagtt caaaagtggg aagctacaca atacggttac aactttgaca
    72001 aagaggctct tgtctttatc gagggtgtgg taccagccat ctcaacagct attcaaacct
    72061 ttacaaaaga aggcgaggcg gttttaatta acacgcctgt ctacccaccc tttgctcgca
    72121 gtgtcaagtt gaataatcgt agattgatta ctaattcctt agtggaaaag gatagtctgt
    72181 ttgagattga ctttgaccaa cttgaaaagg atttggtgga agaggaggtt aaactctatg
    72241 ttctttgcaa ccctcacaat cctggtggac gtgtttggga aaaagaagtg ttggagaaga
    72301 ttggccaact ctgccaaaaa cacggtgttt tgttagtttc ggatgagatt caccaagatt
    72361 tgaccctctt tggtcacaaa caccagtctt tcaataccat caatcctgcc ttcaaaaatt
    72421 ttgctatcgt cttgagcagt gccactaaaa catttaatat tgctggaaca aaaaattcct
    72481 atgcagtcat tgaaaatcct aagttgagac tggctttcca gaaacgcctg ttggccaata
    72541 atcagcatga aatttcaggc ttgggttatt tggcgacaga agctgcctat cgatacggta
    72601 aagattggct agaggaactc aagcaagtct ttgaagacca catcaattat gtggtggatc
    72661 tatttggaaa agagactaaa atcaaggtca tgaaaccgca aggtacctac ttgatttggc
    72721 ttgacttttc agcctatgac ctgactgatg aaacattgca agagttgttg agaaatgaag
    72781 ccaaggttat cctcaaccgt ggtttggatt ttggagagga aggaagtctc catgcccgca
    72841 tcaatatagc tatgcccaaa tctctgttgc aagaagtctg tcagcggatt gtggctactt
    72901 ttgccaaatg ttaaaaatcc agccttctag gagaaaagtc ttcctagaag gctattttca
    72961 taggcgaaaa tatggtataa taaaaagata aggtaaaggt gaaaatatgg ctaaattgat
    73021 tccggggaaa attcgtatcg aaggtgttgc cctttatgaa actggtaagg ttgatatcat
    73081 caaggaaaag aacaatcggc tctacgctcg cgttgcagaa gaagaactgc gctatagttt
    73141 agaggatgat ttggtttttt gtgcctgtga tttttttcaa aagaggggct actgtgtgca
    73201 tttggcagcg ctagagcatt ttctgaaaaa tgatgagcgt ggtcaggaaa tcttgtggag
    73261 tctggaagaa ggtcatgaag aaaaagaggc cgttgaaacc aaggtgacct tgggtggcaa
    73321 gtttttggat cgaattttat ctccaaaatc agaatgcgcc tatgagttat cagctgtggg
    73381 tcaggtggaa gcaggaacca atcatatctt gtggactctg agaatcggcc aaatcaatag
    73441 ccaaaaatac tatgtcattc gggatattcc acttttttta aggattgtcg agcagagaaa
    73501 gtcgtatatg attggcaaga tttatgagga gtctctttct tgggaagcct ttgatgatgc
    73561 cagccaagaa cttttgactt tcttgcacgg actaacggag gaagggctgg ttccagacct
    73621 ctttttccaa aaccaaggtc ggcacctctt tttccctctg accttttttg agcagggtgt
    73681 gaatttactg atggccttgc cccattttca atttgaccat caagtggata gctaccaaac
    73741 cctgcttttt caggatatgc atgctgatgc caatctattt gcctttacag taacagaata
    73801 ttcggactat tttgaaatgg aaatcagtga gagtcctagg gtcaatgtct tttatcaagg
    73861 agcagtactt ttccataaag gtcaggttta ttttttaaca gaccagcaga tgcgtcttct
    73921 caaggaaatt aaagcgttac ctgtggatcg acaaggaaag aaatacctgc aatttgatag
    73981 cagtgatcga gacaaattgg cctcctgtct gactcttttt atccagatgg gcaccgtttc
    74041 agctccagaa cgtctacaaa tcaaaacttt tgcgccctct ttttactttg acagggaaga
    74101 agataatcgg attcgtttag aaattcagtt tgattatgga aatagacagg tatctagccg
    74161 acaagagcta gaagaattac cattttcaag tgacgcggac ttagaagaaa gaattttcca
    74221 agtctgtttg gctgcgggct ttgaagccga ttttcaatct tggcgtcagg ccttaaaagc
    74281 ggagtctgtc tatcattttt ttcatgatat cattccagtc tttgaaaaac tcgggcatgt
    74341 tgacctatca gataaactag aagagcttta tagcctagcg agtcctcagg tgcagattgc
    74401 ctccaaggga ggtctcttgg aaatccagtt tgattttcaa gatattgccc aggaggaaat
    74461 cgaccaagcc atacaggcct tggttgccaa tcaggatttt tatattgatt cgtctaatca
    74521 agtttacttt ttcgatgaag aaaccaagaa aattcgccaa aatctacagg aactggggca
    74581 atttgaatta aaagatggga ccttgcaggc tcggaaatcc ttagcctaca gtttagctca
    74641 tctctttgaa gggcgagacc gtgtttcttt ttcacaagaa ttccagaatc tggcccagga
    74701 tttgacacat ccagaggact ttcctttgca agcaactcag gtcaagactg acttgcgaga
    74761 ttatcaggaa aagggaattg gctggttgca gatgctccat cattatggtt ttggtgggat
    74821 tttggctgat gatatgggac ttgggaaaac ccttcagacc attgcttttt tgactagtca
    74881 agtgacaaaa gaaagtcgag tcttgattct cgctccgtcg ggtttgattt acaactgggc
    74941 ggatgagttt cagaaatttg ctccacagtt ggatgtggct gttgttcatg gtttgaaagc
    75001 aagtcgtgag gagattcttg ccgataacca tcaaatctat gtgactagct atgccacctt
    75061 ccgtcaggac agtgagcttt atcaggggat ggcctttgac ttccttttct tagatgaagc
    75121 tcaggtcatg aaaaatgccc agaccaagat tgcccagacc ttgagacaat ttgtggtgcc
    75181 gtcggtcttt gccttgtcag gaactccgat tgaaaaccat ctgggtgagt tgtggtctat
    75241 tttccaaatc gtcatgcccg gacttttgcc aagcaagaaa gaatttatga aattgccagc
    75301 agagcgagtg gctcagttta tcaagccttt cgtgatgcga cgcaagaaag aagaagttct
    75361 gactgaattg ccagacttga ttgaggtgat ttataaaaat gaactggaag accagcaaaa
    75421 ggctatttac cttgcccagt tacaacagat gcgagaccat ctggctcaag tgtcagaaca
    75481 ggaatttcag cgaagtcgtg tggaaatttt atctggtttg atgcgcttgc gtcaaatatg
    75541 tgacactcct gccctgttta tggaagatta tcagggagcc agcggcaaac tagatagtct
    75601 ccgagaccta ctggtacagg tggcagacgg cggacaccgt gtcttgattt tctctcagtt
    75661 caagggaatg ttggaaaaaa ttgaacaaga actgccagac ttgggcctga cttcctttaa
    75721 aattacgggt tcaaccccag ccaaggaaag acaagacatg accaaggcct ttaaccaagg
    75781 agaaagagat gcctttctga tttccctcaa ggctggtggg gtcggtctga acctgacagg
    75841 tgcagataca gtgatcttgg ttgacctttg gtggaatcct gcggtggaag cgcaagccat
    75901 tggccgtgcc catcggatgg gtcaggaaga aacggttgag gtctatcgct tggtgaccaa
    75961 gggaaccatt gaagaaaaaa ttcaggaact ccaagaacaa aagaaacatc tggtgtcaca
    76021 agtattggac ggcacagagt cacgtggtag tctgacccta gcagaaatta gagaaatttt
    76081 gggaatttct gaagccagca cttgaaaaat caagacaata cgctataatg aagtgttgaa
    76141 aggaaataga aaatgaaaca agaacgattt ccattggtgt cagatgacga ggtcatgttg
    76201 actgaaatgc cagtcatgaa tctctatgat gagtctgatc tgatcagtaa tatcaagggt
    76261 gagtatcgag ataaaaatta tttagaatgg gctcctattg ctgaagaaaa accagtaaaa
    76321 ccgattgaaa agcaagtagg gaaacctaaa aaagctcctt taggggttaa aaaagaagga
    76381 aagagctatg cggaggtggc gcgtgaagaa gcgcgtgcag acttgaaaaa gaaacgctct
    76441 gctaactatc taactcagga tttcagcctt gcgagacgtc attctcagcc cagtctagtt
    76501 agacagggca atcaaccgac aactcctttc caaaaggaaa atcctggtga atttgtcaaa
    76561 tatagccaaa aattgaccca gtctcattat atcttggcgg aagaagttca ttctatccct
    76621 accaagaatg aagaagtgtc agcacctgct ccaaagaaaa acaattatga ttttctaaag
    76681 aagagccaaa tctacaataa aaaaagtaaa caaacagaac aagaacgtcg ggttgcccaa
    76741 gagttgaatc tgaccagaat gacagaatag gggagaaaac atgtcaaaga catatcattt
    76801 tatcggaatt aagggatcag ggatgagtgc cttggccttg atgttgtacc agatggggca
    76861 caaggttcag ggatcagatg ttgaaaagta ctactttacc caacgcggtc ttgagcaggc
    76921 aggaattacc attcttcctt ttgatgaaaa gaatctagac ggtgatatgg aaattatcgc
    76981 tggaaatgcc tttcgtccag ataacaacgt cgaaattgcc tatgcggacc aaaatggtat
    77041 cagctacaaa cgttaccatg agtttctagg tagctttatg cgtgactttg ttagcatggg
    77101 agtagcagga gcacatggaa aaacttcaac gacaggtatg ttgtctcatg tcttgtctca
    77161 cattacagat accagcttct tgattggaga tgggacaggt cgtggttcgg ccaatgccaa
    77221 atattttgtc tttgaatctg acgaatatga gcgtcacttc atgccttacc acccagaata
    77281 ctctattatc accaacattg actttgacca tccagattat ttcacaagtc tcgaggatgt
    77341 tttcaatgcc tttaacgact atgccaaaca aatcaccaag ggtctttttg tctatggtga
    77401 agatgctgaa ttgcgtaaga ttacgtctga tgcaccaatt tattattatg gttttgaagc
    77461 tgaaggcaat gactttgtag ctagtgatct tcttcgttca acaactggtt caaccttcac
    77521 cgttcatttc cgtggacaaa acttggggca attccacatt ccaacctttg gtcgtcacaa
    77581 tatcatgaat gcgacagccg ttattggtct tctttacaca gcaggatttg atttgaactt
    77641 ggtgcgtgag cacttgaaaa cattttccgg tgttaaacgt cgtttcactg agaaaattgt
    77701 caatgataca gtgattatcg atgactttgc ccatcatcca acagaaatta ttgcgacctt
    77761 ggatgcggct cgtcagaaat acccaagcaa ggaaattgta gcagtctttc aaccgcatac
    77821 ctttacaaga accattgcct tgttggacga ctttgcccat gctttaaacc aagcagatgc
    77881 tgtttatcta gcgcaaattt atggctcggc tcgtgaagta gatcatggtg acgttaaggt
    77941 agaagaccta gccaacaaaa tcaacaaaaa acaccaagtg attactgttg aaaatgtttc
    78001 tccactccta gaccatgaca atgctgttta cgtctttatg ggagcaggag acatccaaac
    78061 ctatgaatac tcatttgagc gtctcttgtc taacttgaca agcaatgttc aataggatgt
    78121 tcccatggaa attccaatta agatcattca ggcaagcaag tctgatttgc ctgagatagg
    78181 ggcacttcag acctcgtctt ttccagctga aaagcagcaa ctttcccata ttttagaaga
    78241 aagtatccgt aagtgtgcgg atacctttct tctagctagg gatgaaaatc aacttttagg
    78301 ctatatttta tcaagtcccc agtcagacaa tccgcaatat ctaaaagtac attctttagt
    78361 catcgagtct gaccatcaga gacagggctt gggaacactt cttcttgcag ccttgaaaga
    78421 ggtggcagtt gagctggatt acaaagggat tcgtttggag agtcctgatg agctgctttc
    78481 ctattttgaa atgaacggtt ttgttgatga agaagcaact ttgctctatg caactagcca
    78541 gggctatagt atgatttggt ttaatccctt ttatctggag gaacaatgaa aatcagacaa
    78601 gcaagattag aagatttgga tcggattgtt gaacttgaat ttgaaaattt ttcggtcgaa
    78661 gaagccattc ctccttctgt ctttgaagca catttgagag aaattcagac ctcttttctg
    78721 gttgctgaaa aagaaggaag aatcatgggt tatatcgaag gaccagttgg cctgcaccgc
    78781 catctgcaag accagtcttt tacagaagaa ataaaagact atagtcatga gcctggtggt
    78841 tatatctctg tgacctgtct gtctattgcc aaggaggcac agggactcgg actgggtcag
    78901 aaattgctga cagccttgaa agaagttgct cttgaagatg agagagatgg cattaatcta
    78961 acctgtcatg actatctcat cgcctactat gaaaaacatg gatttgtcaa cgaaggccag
    79021 tcccagtcaa cctttgcagg ggaaacatgg tatgatatgg tctgggaaat gaaaaaataa
    79081 gttaggaaaa gtatcataga ttgctttttt tggactttta agatataata ttatggatta
    79141 tcaacaagga ggaaaaactt ttgagtgaaa agtcaagaga agaagagaaa ttaagcttta
    79201 aagagcagat tctgagagat ttagaaaaag taaaaggcta tgatgaagtt ctgaaagaag
    79261 atgaggcagt agttcgcact cctgcaaatg aaccttcaac tgaagaactc atggctgatt
    79321 ccttgtcaac ggtagaggag attatgagaa aagctcctac cgtgcctact cacccaagtc
    79381 aaggtgtacc agcttctcca gcagatgaga ttcaaagaga aactcctggt gttccaagtc
    79441 atccaagtca agatgtacct tcttctccag cggaagaaag tggatcaaga ccaggtccag
    79501 gtcctgttag acctaagaaa cttgaaagag aatacaatga aaccccaaca agggtagctg
    79561 tttcctatac gacggcagag aaaaaagcag aacaagcagg tccagaaaca cctacgcctg
    79621 ctacagaaac agtggatatc atcagagata catcacgtcg tagccgtaga gaaggagcaa
    79681 aacccgttaa gcctaagaaa gagaagaagt cacatgtgaa agcttttgtg atttcattcc
    79741 ttgtattcct tgccttgctc tcagcaggtg gttactttgg ttaccagtac gtgctagatt
    79801 ccttattacc tatcgatgct aattctaaga aatatgtgac ggttggaatt ccagaaggtt
    79861 caaacgttca agaaatcggt acgacgcttg aaaaagctgg tttggtaaag catggtctga
    79921 tttttagttt ttatgccaag tataaaaatt ataccgactt gaaagcaggt tactacaatt
    79981 tgcaaaagag tatgagtaca gaagacttac tcaaagagtt gcaaaaaggt ggaacagatg
    80041 aaccgcaaga acctgtactt gcgactttga caattccaga aggttatacc ttggatcaga
    80101 ttgctcaagc tgtgggtcaa ttgcaaggtg acttcaaaga gtctttgaca gcggagactt
    80161 tcttggctaa agttcaagat gagacgttta tcagtcaagc agtagcgaaa tatcctactt
    80221 tactggaaag tttgcctgta aaagacagcg gtgcgcgtta tcgtttggaa ggataccttt
    80281 tcccagctac atactctatc aaggaaagca caactattga gagcttgatt gatgagatgt
    80341 tagctgctat ggataagaac ctatctcctt actatagtac tatcaaatct aaaaacttga
    80401 ctgtcaatga gttgttgacc attgcttcct tggtcgaaaa agaaggtgcc aagacagaag
    80461 atcgtaagct cattgcaggt gtattctaca atcgtttgaa tcgtgatatg ccacttcaaa
    80521 gtaatattgc aatcttgtat gcccaaggaa aactggggca aaatatcagt ctagctgagg
    80581 atgttgcgat tgataccaac attgattcac cttataatgt ttataaaaat gtaggtctca
    80641 tgcctggtcc agtcgatagt ccaagtctgg atgcgattga gtcaagcatc aatcaaacta
    80701 agagcgataa cctctacttt gtagcagatg tcacagaagg caaggtctac tatgctaaca
    80761 atcaagaaga ccacgaccgc aatgtcgctg aacatgtcaa cagcaaatta aactaaacaa
    80821 actaaaatta tgttatactt cacataattt tctttagaaa atattatcag aagaaagttg
    80881 agaaaaatgg cagaaaaaac atatcctatg acccttgagg aaaaggaaaa acttgaaaaa
    80941 gaattagaag aattgaaatt ggttcgtcga ccagaagtgg tagaacgcat taagattgcc
    81001 cgttcatacg gtgacctttc agaaaacagt gagtacgaag cagctaagga tgaacaagcc
    81061 tttgtcgaag gacaaatctc tagcttagaa acaaaaatcc gctatgctga aatcgtcaat
    81121 agcgacgcag ttgcccagga cgaagtagcg attggtaaaa cagtcaccat ccaagaaatt
    81181 ggtgaggacg aagaagaagt ttatattatc gtaggttcag ctggtgcgga tgcctttgca
    81241 ggtaaggttt caaatgaaag cccaattggg caggccttga ttggcaagaa aacaggtgat
    81301 acagcaacca ttgaaacgcc tgttggtagc tatgatgtaa aaatcttgaa ggttgaaaaa
    81361 acagcctaaa aacagaaaaa ggagtgggga ggcgatgtgc ttcactcact cctttttcca
    81421 ttttgctatt cttcgaaaat ctcttcaaac cacgtcagcg tcgccttgcc gtatgtatgg
    81481 ttactgactt cgtcagtttc atctacaacc tcaaaaccat gttttgagc
//
LOCUS       DBEJHE010000007        77038 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC4 isolate 671759
            SAMN38261586-rid24793303.denovo.07, whole genome shotgun sequence.
ACCESSION   DBEJHE010000007 DBEJHE010000000
VERSION     DBEJHE010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261586
            Sequence Read Archive: SRR26833752
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 77038)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 77038)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576136.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576136.1
            Genome Coverage       :: 109x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 19:48:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,067
            CDSs (total)                      :: 2,029
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 131
            CDSs (without protein)            :: 131
            Pseudo Genes (ambiguous residues) :: 0 of 131
            Pseudo Genes (frameshifted)       :: 64 of 131
            Pseudo Genes (incomplete)         :: 59 of 131
            Pseudo Genes (internal stop)      :: 46 of 131
            Pseudo Genes (multiple problems)  :: 32 of 131
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..77038
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261586-rid24793303.denovo.07"
                     /strain="GPSC4"
                     /isolate="671759"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(20..499)
                     /locus_tag="ACL3EZ_000620"
     CDS             complement(20..499)
                     /locus_tag="ACL3EZ_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HGR0392237.1"
                     /translation="MIKELYEEVQGTVYKCRNEYYLHLWELSDWDQEGMLCLHELISR
                     EEGLVDDIPRLRKYFKTKFRNRILDYIRKQESQKRRYDKEPYEEVGEISHRISEGGLW
                     LDDYYLFHETLRDYRNKQSKEKQEELERVLSNERFRGRQRVLRDLRIVFKEFTIRTH"
     gene            complement(621..2579)
                     /gene="ftsH"
                     /locus_tag="ACL3EZ_000621"
     CDS             complement(621..2579)
                     /gene="ftsH"
                     /locus_tag="ACL3EZ_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HGR0392238.1"
                     /translation="MKKQNNGLIKNPFLWLLFIFFLVTGFQYFYSGNNSGGSQQINYT
                     ELVQEITDGNVKELTYQPNGSVIEVSGVYKNPKTSKEGTGIQFFTPSVTKVEKFTSTI
                     LPADTTVSELQKLATDHKAEVTVKHESSSGIWINLLVSIVPFGILFFFLFSMMGNMGG
                     GNGRNPMSFGRSKAKAANKEDIKVRFSDVAGAEEEKQELVEVVEFLKDPKRFTKLGAR
                     IPAGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAK
                     KAAPAIIFIDEIDAVGRQRGVGLGGGNDEREQTLNQLLIEMDGFEGNEGIIVIAATNR
                     SDVLDPALLRPGRFDRKVLVGRPDVKGREAILKVHAKNKPLAEDVDLKLVAQQTPGFV
                     GADLENVLNEAALVAARRNKSIIDASDIDEAEDRVIAGPSKKDKTVSQKERELVAYHE
                     AGHTIVGLVLSNARVVHKVTIVPRGRAGGYMIALPKEDQMLLSKEDMKEQLAGLMGGR
                     VAEEIIFNVQTTGASNDFEQATQMARAMVTEYGMSEKLGPVQYEGNHAMFGAQNPQKS
                     ISEQTAYEIDEEVRSLLNEARNKAAEIIQSNRETHKLIAEALLKYETLDSTQIKALYE
                     TGKMPEAVEEESHALSYDEVKSKMNDEK"
     gene            complement(2595..3137)
                     /gene="hpt"
                     /locus_tag="ACL3EZ_000622"
     CDS             complement(2595..3137)
                     /gene="hpt"
                     /locus_tag="ACL3EZ_000622"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006166 - purine ribonucleoside salvage
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HGR0392239.1"
                     /translation="MLENDIKKVLVSHDEITEAAKKLGAQLTKDYAGKNPILVGILKG
                     SIPFMAELVKHIDTHIEMDFMMVSSYHGGTASSGVINIKQDVTQDIKGRHVLFVEDII
                     DTGQTLKNLRDMFKEREAASVKIATLLDKPEGRVVEIEADYTCFTIPNEFVVGYGLDY
                     KENYRNLPYIGVLKEEVYSN"
     gene            complement(3141..4418)
                     /gene="tilS"
                     /locus_tag="ACL3EZ_000623"
     CDS             complement(3141..4418)
                     /gene="tilS"
                     /locus_tag="ACL3EZ_000623"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016879 - ligase activity, forming
                     carbon-nitrogen bonds [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HGR0392240.1"
                     /translation="MREPDFLNHFLKKGYFKKHAKAVLALSGGLDSMFLFKVLSTYQK
                     ELEIELILAHVNHKQRIESDWEEKELRKLAAEAELPIYISNFSGEFSEARARNFRYDF
                     FQEVMKKTGATALVTAHHADDQVETILMRLIRGTRLRYLSGIKEKQVVGEIEIIRPFL
                     HFQKKDFPSIFHFEDTSNQENHYFRNRIRNSYLPELEKENPRFRDAILGIGNEILDYD
                     LAIAELSNNINVEDLQQLFSYSESTQRVLLQTYLNRFPDLNLTKAQFAEVQQILKSKS
                     QYRHPIKNGYELIKEYQQFQICKISPQADEKEDELVLHYQNQVAYQGYLFSFGLPLEG
                     ELIQQIPVSRETSIHIRHRKTGDVLIQNGHRKKLRRLFIDLKIPMEKRNSALIIEQFG
                     EIVSILGIATNNLSKKTKNDIINTVLYIEKIDR"
     gene            complement(4415..5683)
                     /locus_tag="ACL3EZ_000624"
     CDS             complement(4415..5683)
                     /locus_tag="ACL3EZ_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HGR0392241.1"
                     /translation="MRKFLIILLLPSFLTISKVVSTEKEVVYTSKEIYYLSQSDFSIY
                     FREKLSSPMVYGEVPVYANEDLVVESGKLTPKTSFQITEWRLNKQGIPVFKLSNHQFI
                     AADKRFLYDQSEVTPTIKKAWLESDFKLYNSPYDLKEVKSSLSAYSQVSIDKTMFVEG
                     REFLHIDQAGWVAKESTSEEDNRMSKVQEMLSEKYQKDSFSIYVKQLTTGKEAGINQD
                     EKMYAASVLKLSYLYYTQEKINEGLYQLDTTVKYVSAVNDFPGSYKPEGSGSLPKKED
                     NKEYSLKDLITKVSKESDNVAHNLLGYYISNQSDATFKSKMSAIMGDDWDPKEKLISS
                     KMAGKFMEAIYNQNGFVLESLTKTDFDSQRIAKGVSVKVAHKIGDADEFKHDTGVVYA
                     DSPFILSIFTKNSDYDTISKIAKDVYEVLK"
     gene            complement(5676..5798)
                     /locus_tag="ACL3EZ_000625"
     CDS             complement(5676..5798)
                     /locus_tag="ACL3EZ_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0009 family protein"
                     /protein_id="HGR0392242.1"
                     /translation="MENLLDVIEQFLSLSDEKLEELADKNQLLRLQEEKERKNA"
     gene            complement(5803..6171)
                     /locus_tag="ACL3EZ_000626"
     CDS             complement(5803..6171)
                     /locus_tag="ACL3EZ_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HGR0392243.1"
                     /translation="MSKNIVQLNNSFIQNEYQRRRYLMKERQKRNRFMGGVLILIMLL
                     FILPTFNLAQSYQQLLQRRQQLADLQTQYQTLSDEKDKETAFATKLKDEDYAAKYTRA
                     KYYYSKSREKVYTIPDLLQR"
     gene            complement(6164..6430)
                     /locus_tag="ACL3EZ_000627"
     CDS             complement(6164..6430)
                     /locus_tag="ACL3EZ_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HGR0392244.1"
                     /translation="MRLDKYLKVSRIIKRRTVAKEVADKGRIKVNGILAKSSTDLKVN
                     DQVEIRFGNKLLLVKVLEMKDSTKKEDAAGMYEIISETRVEENV"
     gene            complement(6488..9997)
                     /gene="mfd"
                     /locus_tag="ACL3EZ_000628"
     CDS             complement(6488..9997)
                     /gene="mfd"
                     /locus_tag="ACL3EZ_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000258090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HGR0392245.1"
                     /translation="MVTLLDLFSENDQIKKWHQNLTDKKRQLILGLSTSTKALAIASS
                     LEKEDRIVLLTSTYGEAEGLVSDLISILGEELVYPFLVDDAPMVEFLMSSQEKIISRV
                     EALRFLTDSSKKGILVCNIAASRLILPSPNAFKDSIVKISVGEEYDQHAFIHQLKENG
                     YRKVTQVQTQGEFSLRGDILDIFEISQLEPCRIEFFGDEIDGIRSFEVETQLSKENKT
                     ELTIFPASDMLLREKDYQRGQSALEKQISKTLSPILKSYLEEILSSFHQKQSHADSRK
                     FLSLCYDKTWTVFDYIEKDTPIFFDDYQKLMNQYEVFERDLAQYFTEELQNSKAFSDM
                     QYFSDIEQIYKKQSPVTFFSNLQKGLGNLKFDKIYQFNQYPMQEFFNQFSFLKEEIER
                     YKKMDYTIILQSSNSMGSKTLEDMLEEYQIKLDSRDKTSICKESVNLIEGNLRHGFHF
                     VDEKILLITEHEIFQKKLKRRFRRQHVSNAERLKDYNELEKGDYVVHHIHGIGQYLGI
                     ETIEIKGIHRDYVSVQYQNGDQISIPVEQIHLLSKYISSDGKAPKLNKLNDGHFKKAK
                     QKVKNQVEDIADDLIKLYSERSQLKGFAFSADDDDQDAFDDAFPYVETDDQLRSIEEI
                     KRDMQASQPMDRLLVGDVGFGKTEVAMRAAFKAVNDHKQVVILVPTTVLAQQHYTNFK
                     ERFQNFAVNVDVLSRFRSKKEQTATLEKLKNGQVDILIGTHRVLSKDVVFADLGLMII
                     DEEQRFGVKHKETLKELKKQVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPV
                     QTYVLEKNDSVIRDAVLREMERGGQVYYLYNKVDTIVQKVSELQELIPEASIGYVHGR
                     MSEVQLENTLLDFIEGQYDILVTTTIIETGVDIPNANTLFIENADHMGLSTLYQLRGR
                     VGRSNRIAYAYLMYRPEKSISEVSEKRLEAIKGFTELGSGFKIAMRDLSIRGAGNLLG
                     KSQSGFIDSVGFELYSQLLEEAIAKRNGNANANTRTKGNAELILQIDAYLPDTYISDQ
                     RHKIEIYKKIRQIDNRVNYEELQEELIDRFGEYPDVVAYLLEIGLVKSYLDKVFVQRV
                     ERKDNKITIQFEKVTQRLFLAQDYFKALSVTNLKAGIAENKGLMELVFDVQNKKDYEI
                     LEGLLIFGESLLEIKEFKEENSI"
     gene            complement(9998..10567)
                     /gene="pth"
                     /locus_tag="ACL3EZ_000629"
     CDS             complement(9998..10567)
                     /gene="pth"
                     /locus_tag="ACL3EZ_000629"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004045 - aminoacyl-tRNA hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HGR0392246.1"
                     /translation="MTKLLVGLGNPGDKYFETKHNVGFMLIDQLAKKQNVTFTHDKIF
                     QADLASFFLNGEKIYLVKPTTFMNESGKAVHALLTYYGLDIDDLLIIYDDLDMEVGKI
                     RLRAKGSAGGHNGIKSIIQHIGTQVFNRVKIGIGRPKNGMSVVHHVLSKFDRDDYIGI
                     LQSVDKVDDSVKYYLQEKNFEKTMQRYNG"
     gene            complement(10639..11754)
                     /gene="ychF"
                     /locus_tag="ACL3EZ_000630"
     CDS             complement(10639..11754)
                     /gene="ychF"
                     /locus_tag="ACL3EZ_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HGR0392247.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDERLQKLTEMITPKKTVPTTFEFTDIAGIVKGASKGEGLGNKFLANIREVDAIVH
                     VVRAFDDENVMREQGREDAFVDPLADIDTINLELILADLESVNKRYARVEKMARTQKD
                     KESVAEFNVLQKIKPVLEDGKSARTIEFTDEEQKVVKGLFLLTTKPVLYVANVDEDVV
                     SEPDSIDYVKQIREFAATENAEVVVISARAEEEISELDDEDKKEFLEAIGLTESGVDK
                     LTRAAYHLLGLGTYFTAGEKEVRAWTFKRGMKAPQAAGIIHSDFEKGFIRAVTMSYED
                     LVKYGSEKAVKEAGRLREEGKEYIVQDGDIMEFRFNV"
     gene            complement(11838..12032)
                     /locus_tag="ACL3EZ_000631"
     CDS             complement(11838..12032)
                     /locus_tag="ACL3EZ_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 family protein"
                     /protein_id="HGR0392248.1"
                     /translation="MYQVGNFVEMKKSHACTIKSTGKKANRWEITRVGADIKIKCSNC
                     EHVVMMGRYDFERKMNKIID"
     gene            complement(12097..13233)
                     /gene="dnaN"
                     /locus_tag="ACL3EZ_000632"
     CDS             complement(12097..13233)
                     /gene="dnaN"
                     /locus_tag="ACL3EZ_000632"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009360 - DNA polymerase III complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HGR0392249.1"
                     /translation="MIHFSINKNLFLQALNTTKRAISSKNAIPILSTVKIDVTNEGIT
                     LIGSNGQISIENFISQKNEDAGLLITSLGSILLEASFFINVVSSLPDVTLDFKEIEQN
                     QIVLTSGKSEITLKGKDSEQYPRIQEISASTPLILETKLLKKIINETAFAASTQESRP
                     ILTGVHFVLSQHKELKTVATDSHRLSQKKLTLEKNSDDFDVVIPSRSLREFSAVFTDD
                     IETVEIFFANNQILFRSENISFYTRLLEGNYPDTDRLIPTDFNTTITFNVVNLRQSME
                     RARLLSSATQNGTVKLEIKDGVVSAHVHSPEVGKVNEEIDTDQVTGEDLTISFNPTYL
                     IDSLKALNSEKVTISFISAVRPFTLVPADTDEDFMQLITPVRTN"
     gene            complement(13392..14753)
                     /gene="dnaA"
                     /locus_tag="ACL3EZ_000633"
     CDS             complement(13392..14753)
                     /gene="dnaA"
                     /locus_tag="ACL3EZ_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003688 - DNA replication origin binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA];
                     GO_process: GO:0006275 - regulation of DNA replication
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HGR0392250.1"
                     /translation="MKEKQFWNRILEFAQERLTRSMYDFYAIQAELIKVEENVATIFL
                     PRSEMEMVWEKQLKDIIVVAGFEIYDAEITPHYIFTKPQDTTSSQVEEATNLTLYDYS
                     PKLVSIPYSDTGLKEKYTFDNFIQGDGNVWAVSAALAVSEDLALTYNPLFIYGGPGLG
                     KTHLLNAIGNEILKNIPNARVKYIPAESFINDFLDHLRLGEMEKFKKTYRSLDLLLID
                     DIQSLSGKKVATQEEFFNTFNALHDKQKQIVLTSDRSPKHLEGLEERLVTRFSWGLTQ
                     TITPPDFETRIAILQSKTEHLGYNFQSDTLEYLAGQFDSNVRDLEGAINDITLIARVK
                     KIKDITIDIAAEAIRARKQDVSQMLVIPIDKIQTEVGNFYGVSIKEMKGSRRLQNIVL
                     ARQVAMYLSRELTDNSLPKIGKEFGGKDHTTVIHAHAKIKSLIDQDDNLRLEIESIKK
                     KIK"
     gene            complement(14966..15724)
                     /locus_tag="ACL3EZ_000634"
     CDS             complement(14966..15724)
                     /locus_tag="ACL3EZ_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HGR0392251.1"
                     /translation="MEKFEMISITDIQKNPYQPRKEFDREKLDELAQSIKENGVIQPI
                     IVRQSPVIGYEILAGERRYRASLLAGLRSIPAVVKQISDQEMMVQSIIENLQRENLNP
                     IEEARAYESLVEKGFTHAEIADKMGKSRPYISNSIRLLSLPEQILSEVENGKLSQAHA
                     RSLVGLNKEQQDYFFQRIIEEDISVRKLEALLTEKKQKKQQKTNHFIQNEEKQLRKLL
                     GLDVEIKLSKKDSGKIIISFSNQEEYSRIINSLK"
     gene            complement(15782..16963)
                     /locus_tag="ACL3EZ_000635"
     CDS             complement(15782..16963)
                     /locus_tag="ACL3EZ_000635"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S1C family serine protease"
                     /protein_id="HGR0392252.1"
                     /translation="MKHLKTFYKKWFQLLVVIVISFFSGALGSFSITQLTQKSSVNNS
                     NNNSTITQTAYKNENSTTQAVNKVKDAVVSVITYSANRQNSVFGNDDTDTDSQRISSE
                     GSGVIYKKNDKEAYIVTNNHVINGASKVDIRLSDGTKVPGEIVGADTFSDIAVVKISS
                     EKVTTVAEFGDSSKLTVGETAIAIGSPLGSEYANTVTQGIVSSLNRNVSLRSEDGQAI
                     STKAIQTDTAINPGNSGGPLINIQGQVIGITSSKIATNGGTSVEGLGFAIPANDAINI
                     IEQLEKNGKVTRPALGIQMVNLSNVSTSDIRRLNIPSNVTSGVVVRSVQSNMPANGHL
                     EKYDVITKVDDKEIASSTDLQSALYNHSIGDTIKITYYRNGKEETTSIKLNKSSGDLE
                     S"
     gene            17146..17625
                     /gene="rlmH"
                     /locus_tag="ACL3EZ_000636"
     CDS             17146..17625
                     /gene="rlmH"
                     /locus_tag="ACL3EZ_000636"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HGR0392253.1"
                     /translation="MKIKVVTVGKLKEKYLKDGIAEYSKRISRFAKFEMIELSDEKTP
                     DKASESENQKILEIEGQRILSKIADRDFVIVLAIEGKTFFSEEFSKQLEETSIKGFST
                     LTFIIGGSLGLSSSVKNRANLSVSFGRLTLPHQLMRLVLVEQIYRAFTIQQGFPYHK"
     gene            17669..17742
                     /locus_tag="ACL3EZ_000637"
     tRNA            17669..17742
                     /locus_tag="ACL3EZ_000637"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:17703..17705,aa:Arg,seq:tct)
     gene            17908..18033
                     /gene="comC"
                     /locus_tag="ACL3EZ_000638"
     CDS             17908..18033
                     /gene="comC"
                     /locus_tag="ACL3EZ_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence-stimulating peptide ComC"
                     /protein_id="HGR0392254.1"
                     /translation="MKNTVKLEQFVALKEKDLQKIKGGEMRLSKFFRDFILQRKK"
     gene            18054..19379
                     /gene="comD"
                     /locus_tag="ACL3EZ_000639"
     CDS             18054..19379
                     /gene="comD"
                     /locus_tag="ACL3EZ_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000362880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence system sensor histidine kinase ComD"
                     /protein_id="HGR0392255.1"
                     /translation="MDLFGFGTVIVHLLIISHNYHLICKGQINRKELFVFGAYTLLTE
                     IVFDFPLYILYLDGLGIAIFLFPLGLYSYFRWMKQYERDRGLFLSLLLSLLYESTHNF
                     LSVTFSSITGDNFVLQYHFPFFFVVTVLTYFVTLKIIYYFHLELAYFDKDYLYPFLKK
                     VFFALLLLHIVSFVSDMVSTIKHLNSFGSILSSIVFISLLLTFFAMNSHKVQMEKEIA
                     LKQKKFEQKHLQNYTDEIVGLYNEIRGFRHDYAGMLVSMQMAIDSGNLQEIDRIYNEV
                     LVKANHKLRSDKYTYFDLNNIEDSALRSLVAQSIVYARNNGVEFTLEVKDTITKLPIE
                     LLDLVRIMSVLLNNAVEGSADSYKKQMEVAVIKMETETVIVIQNSCKMTMTPSGDLFS
                     LGFSTKGRNRGVGLNNVKELLDKYNNIILETEMEGSTFRQIIRFKREFE"
     gene            19376..20128
                     /gene="comE"
                     /locus_tag="ACL3EZ_000640"
     CDS             19376..20128
                     /gene="comE"
                     /locus_tag="ACL3EZ_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000866065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence system response regulator
                     transcription factor ComE"
                     /protein_id="HGR0392256.1"
                     /translation="MKVLILEDVIEHQVRLERILDEISKESNIPISYKTTGKVREFEE
                     YIENDEVNQLYFLDIDIHGIEKKGFEVAQFIRHYNPYAIIVFITSRSEFATLTYKYQV
                     SALDFVDKDINDEMFKKRIEQNIFYTKSMLLENEDVVDYFDYNYKGNDLKIPYHDILY
                     IETTGVSHKLRIIGKNFAKEFYGTMTDIQEKDKHTQRFYSPHKSFLVNIGNIREIDRK
                     NLEIVFYEDHRCPISRLKIRKLKDILEKKSQK"
     gene            20180..20251
                     /locus_tag="ACL3EZ_000641"
     tRNA            20180..20251
                     /locus_tag="ACL3EZ_000641"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:20213..20215,aa:Glu,seq:ttc)
     gene            20257..20330
                     /locus_tag="ACL3EZ_000642"
     tRNA            20257..20330
                     /locus_tag="ACL3EZ_000642"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:20291..20293,aa:Asn,seq:gtt)
     gene            complement(20371..20913)
                     /locus_tag="ACL3EZ_000643"
     CDS             complement(20371..20913)
                     /locus_tag="ACL3EZ_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HGR0392257.1"
                     /translation="MQESNKRLKTKRTIENAMVQLLMEQPFDKISTVKLVEKAGISRS
                     SFYTHYKDKYDMIEHYQSKLFHTFEYIFQKHAHHKRDAILEVFEYLESEPLLAALLSE
                     NGTKEIQNFLRNKLHIMLSTDLQKRFMQLNLNTTELEYSSIYLTHALFGVCQTWIAHG
                     KKESSQEITDFLMKMLGDTN"
     gene            21092..22695
                     /locus_tag="ACL3EZ_000644"
                     /pseudo
     CDS             21092..22695
                     /locus_tag="ACL3EZ_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518194.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip family protein"
     gene            complement(22725..25277)
                     /locus_tag="ACL3EZ_000645"
     CDS             complement(22725..25277)
                     /locus_tag="ACL3EZ_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HGR0392258.1"
                     /translation="MKSFLKTYRTYFISFIIPVVIMSGVYLSQGIYWNSDNSPLLGDG
                     FHQYVIFDVALRNILHGNSNLFYTFTSGLGLNFYALSSYYLGSFLAPLVYFFDLTNMP
                     DAIYLTTLLKFGLIGLSTFFSLNKLFQSIPQILKLALSTSYALMSFTVSQLEIKTWLD
                     VFILIPLIITGLHLLITEKKLLLYFTSLSILFIQNYYFGYMTVLFLIFWYLCQISWDF
                     KTRKSSVLDFIVISFLAGMASLIMTLPTLFDLQTHGEKLTEVTKFQTESSWYLDLFAK
                     QFIGSFDTTKYGAIPMIFVGLLPFILTILFFTLKSIKFHVKLIYVIFFAFLIASFYIE
                     ALDLFWQGMHTPNMFLHRYAWIFSTLLIYTAAEVLNRLKELKVWNFLVSLFLVVAGFL
                     ATIYLKSHYSFLTDLNILLTLEFLVVYSLLLLAVIKKFISVNLFAILISLFILVEMSL
                     NASSQMDGIAKEWGFASRSAYSRDIPAMESFSTYIGNQFTRTEKLQTQTGNDSMKFNY
                     NGISQFSSVRNRSSSSTLDKLGFKSSGTNLNLRYANNSILADSLFGIQYNISDSPIDK
                     YGFKDIYQKDNLTLYENQYSLPIAVASQSVYNDVKFNEHTLDNQASFLNQLANVNFDY
                     FSPIPYEKTEKIENTNDLISVTSSSNEDAAIQYQIEVPENSQVYLSFINLHFSNDKQK
                     KVDILVNGEKKTFTTDNVFSFFNLGYTKEKKTFNINVSFPGNSQVSFESPTFYRLDTK
                     TFTEAIQKIKEQPVTVSTSKNKVFATYDVQQDTSIFFTIPYDKGWSAYQDGKKIEIKQ
                     AQTGFMKVDIPKGKGTITLSFIPNGFITGAICSFTSLLLFGIYNHRRKSSKA"
     gene            complement(25339..26961)
                     /locus_tag="ACL3EZ_000646"
     CDS             complement(25339..26961)
                     /locus_tag="ACL3EZ_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGR0392259.1"
                     /translation="MLTVSDVSLRFSDRKLFDDVNIKFTEGNTYGLIGANGAGKSTFL
                     KILAGDIEPTTGHISLGPDERLSVLRQNHFDYEDERAIDVVIMGNEKLYSIMKEKDAI
                     YMKEDFSDEDGVRAAELEGEFAELGGWEAESEASQLLQNLNIPEELHYQNMSELANGE
                     KVKVLLAKALFGKPDVLLLDEPTNGLDIQSITWLEDFLIDFDNTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWKESSELAAKLLADRNAKAEEKIKQLQEFVARFSANA
                     SKSRQATSRKKMLDKIELEEIVPSSRKYPFINFKAEREIGNDLLTVENLTVKIDGETI
                     LDNISFILRPDDKTALIGQNDIQTTALIRAIMGDIDYEGTVKWGVTTSQSYLPKDNSA
                     DFAGGESILDWLRQFASKEEDDNTFLRGFLGRMLFSGDEVNKPVNVLSGGEKVRVMLS
                     KLMLLKSNVLVLDDPTNHLDLESISSLNDGLKNFKESIIFASHDHEFIQTLANHIIVL
                     SKNGVIDRIDETYDEFLENAEVQAKVKELWKD"
     gene            27167..28192
                     /gene="trpS"
                     /locus_tag="ACL3EZ_000647"
     CDS             27167..28192
                     /gene="trpS"
                     /locus_tag="ACL3EZ_000647"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004830 - tryptophan-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006436 - tryptophanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HGR0392260.1"
                     /translation="MTKPIILTGDRPTGKLHIGHYVGSLKNRVLLQEEDKYDMFVFLA
                     DQQALTDHAKDPQTIVESIGNVALDYLAVGLDPNKSTIFIQSQIPELAELSMYYMNLV
                     SLARLERNPTVKTEISQKGFGESIPTGFLVYPIAQAADITAFKANYVPVGTDQKPMIE
                     QTREIVRSFNNAYNCDVLVEPEGIYPENERAGRLPGLDGNAKMSKSLNNGIYLADDAD
                     TLRKKVMSMYTDPDHIRVEDPGKIEGNMVFHYLDVFGRPEDAQEIADMKERYQRGGLG
                     DVKTKRYLLEILERELGPIRERRIEFAKDMGEVYNMIQKGSERAREVAGQTLSEVKGA
                     MGLHYFN"
     gene            28344..29822
                     /gene="guaB"
                     /locus_tag="ACL3EZ_000648"
     CDS             28344..29822
                     /gene="guaB"
                     /locus_tag="ACL3EZ_000648"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003938 - IMP dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HGR0392261.1"
                     /translation="MSNWDTKFLKKGFTFDDVLLIPAESHVLPNDADLTTKLADNLTL
                     NIPIITAAMDTVTESQMAIAIARAGGLGVIHKNMSIAQQADEVRKVKRSENGVIIDPF
                     FLTPEHTIAEADELMGRYRISGVPVVETLENRKLVGILTNRDLRFISDYNQPISNHMT
                     SENLVTAPVGTDLATAESILQEHRIEKLPLVDEEGSLSGLITIKDIEKVIEFPNAAKD
                     EFGRLLVAGAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPDR
                     TLIAGNIATAEGARALYEAGVDVVKVGIGPGSICTTRVIAGVGVPQVTAIYDAAAVAR
                     EYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIFQGRKFKTYRG
                     MGSIAAMKKGSSDRYFQGSVNEANKLVPEGIEGRVAYKGAAADIVFQMIGGIRSGMGY
                     CGAANLKELHDNAQFIEMSGAGLKESHPHDVQITNEAPNYSM"
     gene            complement(29873..30970)
                     /gene="recF"
                     /locus_tag="ACL3EZ_000649"
     CDS             complement(29873..30970)
                     /gene="recF"
                     /locus_tag="ACL3EZ_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HGR0392262.1"
                     /translation="MWLQHLSLKTFRNYKETKIDFNPKLNVFLGRNAQGKTNMLEAIY
                     FLALTRSHRTRTDKNLIHFDEEQLHLSGLVQKKTGSIPLEIELTQKGRVTKVNHLKQA
                     RLSDYVGHMNVVLFAPEDLQLIKGAPSIRRKFIDMELGQIKPIYLSDLTNYNHILKQR
                     NTYLKSAQKIDETFLSVLDDQLVDYGCRVMNHRLDFIKKLESFGRKKHFELSNQIEEL
                     SISYQSSVNITDKQNLSESFKIALEKSRSRDLFKKNTGVGPHRDDISFYINGMDASFG
                     SQGQHRSLVLSIKLAEIELMESITTESPILLLDDVMSELDNTRQLKLLETISQSIQTF
                     ITTTSLDHLQNLPENLSIFTIQDGKAAVNGN"
     gene            complement(30973..31341)
                     /gene="yaaA"
                     /locus_tag="ACL3EZ_000650"
     CDS             complement(30973..31341)
                     /gene="yaaA"
                     /locus_tag="ACL3EZ_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HGR0392263.1"
                     /translation="MEYKLFEEFITLQALLKELGITHSGGAIKSFLSEHSVYFNRELE
                     SRRGKKLRIGDKVDIPDMNIDILLTQPTSEEQDEYQADKVEKERIAKLVKKMNKGVKK
                     DKSKPASSPKSQQAPRFPGR"
     gene            31500..32750
                     /locus_tag="ACL3EZ_000651"
     CDS             31500..32750
                     /locus_tag="ACL3EZ_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M16 family metallopeptidase"
                     /protein_id="HGR0392264.1"
                     /translation="MELVHGISTHFIQSKKFKTNKITVRFTAPLSLDTIAGHMLSASM
                     LETANQMYPTSQDLRRHLASLYGTDMSTNCFRRGQSHIIELTFTYVRDEFLSRKNVLT
                     SQILELVKETLFSPVVVDNGFDPALFEIEKKQLLASLAADMDDSFYFAHKELDKLFFH
                     DERLQLEYSDLRNRILAETPQSSYSCFQEFLANDRIDFFFLGDFNEVEIQNVLESFGF
                     KGRKGDVKVQYCQPYSNILQEGMVRKNVGQSILELGYHYRSKYGDEQHLPMIVMNGLL
                     GGFAHSKLFTNVRENAGLAYTISSELDLFSGFLRMYAGINRENRNQARKMMNNQLLDL
                     KKGYFTEFELNQTKEMIRWSLLLSQDNQSSLIERAYQNALFGKSSADFKSWIAKLEQI
                     DKDAICRVANNVKLQAIYFMEGIE"
     gene            32747..34030
                     /locus_tag="ACL3EZ_000652"
     CDS             32747..34030
                     /locus_tag="ACL3EZ_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M16 family metallopeptidase"
                     /protein_id="HGR0392265.1"
                     /translation="MTKVVFEEKYYPAVKEMVYRTRLANGLTVALLPKKEFKEVYGSV
                     TVQFGSVDTFVTEVDGDVKQYPGGIAHFLEHKLFEREDSSDLMSAFTSLGADSNAFTS
                     FTKTNYLFSATDYFLENLDLLDELVTSAHFTEASILTEQDIIQQEREMYQDDPDSCLF
                     FSTLANLYPGTPLATDIVGSEESISQINLTNLQENFTKFYKPVNMSLFLVGNFDVERV
                     QDYFESKELKDSDFQEVAREKLFLQPVKPTDSMRMEVSSPKLAIGVRGKREVSEADCY
                     RHHILLKLLFAMMFGWTSDRFQKCYESGKIDASLSLEVEITSRFHFVMLTMDTKEPVA
                     LSHQFRKAIRNFTKDLDITEEHLDIIKREMFGEFFSSMNSLEFIATQYDAFENGETIF
                     DLPKILQEITLEDVLDAGHHLIDDGDIVDFTIFPS"
     gene            34072..34893
                     /gene="rodZ"
                     /locus_tag="ACL3EZ_000653"
     CDS             34072..34893
                     /gene="rodZ"
                     /locus_tag="ACL3EZ_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytoskeleton protein RodZ"
                     /protein_id="HGR0392266.1"
                     /translation="MRKKTIGEVLRLARINQGLSLDELQKKTEIQLDMLEAMEADDFD
                     QLPSPFYTRSFLKKYAWAVELDDQIVLDAYDSGSMITYEEVDVDEDELTGRRRSSKKK
                     KKKISFLPLFYFILFALSILIFVTYYVWNYIQTQPEEPSLSNYSVVQSTSSTSSVPHS
                     SSSSSSSIESAISVSGEGNHVEIAYKTSKETVKLQLAVSDVTSWVSVSESELEGGVTL
                     SPKKKSAEATVATKSPVTITLGVVKGVDLTVDNQTVDLSKLTAQTGQITVTFTKN"
     gene            34904..35449
                     /gene="pgsA"
                     /locus_tag="ACL3EZ_000654"
     CDS             34904..35449
                     /gene="pgsA"
                     /locus_tag="ACL3EZ_000654"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008444 -
                     CDP-diacylglycerol-glycerol-3-phosphate
                     3-phosphatidyltransferase activity [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HGR0392267.1"
                     /translation="MKKEQIPNLLTIGRILFIPIFIFILTIGNSIESHIVAAIIFAVA
                     SITDYLDGYLARKWNVVSNFGKFADPMADKLLVMSAFIMLIELGMAPAWIVAVIICRE
                     LAVTGLRLLLVETGGTILAAAMPGKIKTFSQMFAIIFLLLHWTLLGQVLLYVALFFTI
                     YSGYDYFKGSAYVFKGTFGSK"
     gene            35446..36273
                     /locus_tag="ACL3EZ_000655"
     CDS             35446..36273
                     /locus_tag="ACL3EZ_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HGR0392268.1"
                     /translation="MKSIIDVKNLSFRYKENQNYYDVKDITFHVKRGEWLSIVGHNGS
                     GKSTTVRLIDGLLEAESGEIVIDGQRLTEENVWNIRRQIGMVFQNPDNQFVGATVEDD
                     VAFGLENQGLSRQEMKKRVEEALALVGMLDFKKREPARLSGGQKQRVAIAGVVALRPA
                     ILILDEATSMLDPEGRRELIGTVKGIRKDYDMTVISITHDLEEVAMSDRVLVMKKGEI
                     ESTSSPRELFSRNDLDQIGLDDPFANQLKKSLSQNGYDLPENYLTESELEDKLWELL"
     gene            36258..37097
                     /locus_tag="ACL3EZ_000656"
     CDS             36258..37097
                     /locus_tag="ACL3EZ_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000510406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HGR0392269.1"
                     /translation="MGIALENVNFTYQEGTPLASAALSDVSLTIEDGSYTALIGHTGS
                     GKSTILQLLNGLLVPSQGSVRVFDTLITSTSKNKDIRQIRKQVGLVFQFAENQIFEET
                     VLKDVAFGPQNFGVSEEDAVKTAREKLALVGIDESLFDRSPFELSGGQMRRVAIAGIL
                     AMEPAILVLDEPTAGLDPLGRKELMTLFKKLHQSGMTIVLVTHLMDDVAEYANQVYVM
                     EKGRLVKGGKPSDVFQDVVFMEEVQLGVPKITAFCKRLADRGVSFKRLPIKIEEFKES
                     LNG"
     gene            37090..37884
                     /locus_tag="ACL3EZ_000657"
     CDS             37090..37884
                     /locus_tag="ACL3EZ_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HGR0392270.1"
                     /translation="MDSMILGRYIPGDSIVHRLDPRSKLLAMMLLILIVFWANNPLTN
                     LILFIATGIFIALSGVSLSFFIQGLKSMFFLIAFTTIFQLFFISNGNVLFEFSFVRIT
                     DYALQQAGIIFCRFVLIIFFSTLLTLTTMPLSLASAVEALLAPLKRVKVPVHEIGLML
                     SMSLRFVPTLMDDTTRIMNAQKARGVDFGEGSIVQKVKAMIPILIPLFATSLKRADSL
                     AIAMEARGYQGGKGRSQYRQLKWTLKDTLTILVILVLGCCLFFLKS"
     gene            37943..38761
                     /gene="mreC"
                     /locus_tag="ACL3EZ_000658"
     CDS             37943..38761
                     /gene="mreC"
                     /locus_tag="ACL3EZ_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HGR0392271.1"
                     /translation="MNRFKKSKYVIIVFVTVLLVSALLATTYSSTIVTKLGDGISLVD
                     RVVQKPFQWFDSVKSDLAHLTRTYNENESLKKQLYQLEVKSNEVESLKTENEQLRQLL
                     DMKSKLQATKTLAADVIMRSPVSWKQELTLDAGRSKGASENMLAIANGGLIGSVSKVE
                     ENSTIVNLLTNTENADKISVKIQHGSTTIYGIIIGYDKENDVLKISQLNSNSDISAGD
                     KVTTGGLGNFNVADIPVGEVVATTHSTDYLTREVTVKLSADTHNVDVIELVGNS"
     gene            38761..39255
                     /gene="mreD"
                     /locus_tag="ACL3EZ_000659"
     CDS             38761..39255
                     /gene="mreD"
                     /locus_tag="ACL3EZ_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HGR0392272.1"
                     /translation="MRQLKRVGVFLLLPFFVLIDAHISQLLGSFFPHVHLASHFLFLF
                     LLFETIEVSEYLYLVYCFVIGLVYDVYFFHLIGITTLLFILLGAFLHKLNSVILLNRW
                     TRMLAMIVLTFLFEMGSYLLAFMVGLTVDSMSIFIVYSLVPTMILNFLWITVFQFIFE
                     KYYL"
     gene            39349..40527
                     /gene="pcsB"
                     /locus_tag="ACL3EZ_000660"
     CDS             39349..40527
                     /gene="pcsB"
                     /locus_tag="ACL3EZ_000660"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan hydrolase PcsB"
                     /protein_id="HGR0392273.1"
                     /translation="MKKKILASLLLSTVMVSQVAVLTTAHAETTDDKIAAQDNKISNL
                     TAQQQEAQKQVDQIQEQVSAIQAEQSNLQAENDRLQAESKKLEGEITELSKNIVSRNQ
                     SLEKQARSAQTNGAVTSYINTIVNSKSITEAISRVAAMSEIVSANNKMLEQQKADKKA
                     ISEKQVANNDAINTVIANQQKLADDAQALTTKQAELKAAELSLAAEKATAEGEKASLL
                     EQKAAAEAEARAAAVAEAAYKEKRASQQQSVLASANTNLTAQVQAVSESAAAPVRAKV
                     RPTYSTNASSYPIGECTWGVKTLAPWAGDYWGNGAQWATSAAAAGFRTGSTPQVGAIA
                     CWNDGGYGHVAVVTAVESTTRIQVSESNYAGNRTIGNHRGWFNPTTTSEGFVTYIYAD
                     "
     gene            40751..41530
                     /gene="rpsB"
                     /locus_tag="ACL3EZ_000661"
     CDS             40751..41530
                     /gene="rpsB"
                     /locus_tag="ACL3EZ_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HGR0392274.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQ
                     QTVKYADQAYDFMRDAAANDAVVLFVGTKKQAADAVAEEAVRSGQYFINHRWLGGTLT
                     NWGTIQKRIARLKEIKRMEEDGTFEVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDV
                     MYVVDPHKEQIAVKEAKKLGIPVVAMVDTNTDPDDIDVIIPANDDAIRAVKLITAKLA
                     DAIIEGRQGEDAVAVEAEFAASETQADSIEEIVEVVEGDNA"
     gene            41609..42649
                     /gene="tsf"
                     /locus_tag="ACL3EZ_000662"
     CDS             41609..42649
                     /gene="tsf"
                     /locus_tag="ACL3EZ_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation elongation factor Ts"
                     /protein_id="HGR0392275.1"
                     /translation="MAEITAKLVKELREKSGAGVMDAKKALVETDGDIEKAIELLREK
                     GMAKAAKKADRVAAEGLTGVYVNGNVAAVIEVNAETDFVAKNAQFVELVNTTAKVIAE
                     GKPANNEEALALIMPSGETLEAAYVSATATIGEKISFRRFALIEKTDAQHFGAYQHNG
                     GRIGVISVVEGGDEALAKQLSMHIAAMKPTVLSYKELDEQFVKDELAQLNHVIDQDNE
                     SRAMVNKPALPHLKYGSKAQLTDDVIAQAEADIKAELAAEGKPEKIWDKIIPGKMDRF
                     MLDNTKVDQAYTLLAQVYIMDDSKTVEAYLESVNASVVEFARFEVGEGIEKAANDFEA
                     EVAATMAAALNN"
     gene            42896..43219
                     /gene="tnpB"
                     /locus_tag="ACL3EZ_000663"
     CDS             42896..43219
                     /gene="tnpB"
                     /locus_tag="ACL3EZ_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849103.1"
                     /note="TnpB, as the term is used for proteins encoded by
                     IS66 family insertion elements, is considered an accessory
                     protein, since TnpC, encoded by a neighboring gene, is a
                     DDE family transposase; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HGR0392276.1"
                     /translation="MIIQLSDLGQVHLVCSKIDMRQGIDSLAYVVKTHFELDPFSGQV
                     FLFCGGRKDRFKALYWDGQGFWLLYKRFENVRLTWPSTEKDVKALTPEQVDWLMKGFS
                     ITPKI"
     gene            complement(43374..43682)
                     /locus_tag="ACL3EZ_000664"
                     /pseudo
     CDS             complement(43374..43682)
                     /locus_tag="ACL3EZ_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            43664..44193
                     /locus_tag="ACL3EZ_000665"
                     /pseudo
     CDS             43664..44193
                     /locus_tag="ACL3EZ_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_050084071.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(44268..45188)
                     /gene="cysK"
                     /locus_tag="ACL3EZ_000666"
     CDS             complement(44268..45188)
                     /gene="cysK"
                     /locus_tag="ACL3EZ_000666"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004124 - cysteine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HGR0392277.1"
                     /translation="MSIYNNITELIGQTPIVKLNNIVPEGAADVYIKLEAFNPGSSVK
                     DRIALSMIEKAEQDGILKLGSTIVEATSGNTGIGLSWVGAAKGYKVVIVMPETMSVER
                     RKIIQAYGAELVLTPGSEGMKGAIAKAQEIAAERDGFLPLQFDNPANPEVHERTTGAE
                     ILAAFGKDGLDAFVAGVGTGGTISGVSHALKSENSNIQVFAVEADESAILSGEKPGPH
                     KIQGISAGFIPDTLDTKAYDGIVRVTSDDALALGREIGGKEGFLVGISSAAAIYGAIE
                     VAKKLGTGKKVLALAPDNGERYLSTALYEL"
     gene            complement(45473..46108)
                     /locus_tag="ACL3EZ_000667"
     CDS             complement(45473..46108)
                     /locus_tag="ACL3EZ_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HGR0392278.1"
                     /translation="MEFRTIKEDGQVQEEIKKSRFICHAKRVYSEEEARDFITAIKKE
                     HYKATHNCSAFIIGERSEIKRTSDDGEPSGTAGVPMLGVLENHNLTNVCVVVTRYFGG
                     IKLGAGGLIRAYAGSVALAVKEIGIIEIKEQAGIAIQMSYAQYQEYSNFLKEHDLMEL
                     DTNFTDQVDTMIYVDKEEKETIKAALVEFFNGKVTLTDQGLREVEVPVNLV"
     gene            46164..47462
                     /locus_tag="ACL3EZ_000668"
     CDS             46164..47462
                     /locus_tag="ACL3EZ_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HGR0392279.1"
                     /translation="MKVNLDYLGRLFTENELTEEERQLAEKLPAMRKEKGKLFCQRCN
                     STILAEWYLPIGAYYCRECLLMKRVRSDQTLYYFPQEDFPKQDVLKWRGQLTPFQEKV
                     SEGLLQAVDKQKPTLVHAVTGAGKTEMIYQVVAKVINAGGAVCLASPRIDVCLELYKR
                     LQQDFSCGIALLHGESEPYFRTPLVVATTHQLLKFYQAFDLLIVDEVDAFPYVDNPTL
                     YHAVKNSVKENGLRIFLTATSTNELDKKVRLGELKRLNLPRRFHGNPLIIPKPIWLSD
                     FNRYLDKNRLSPKLKSYIEKQRKTAYPLLIFASEIKKGEQLEEILQEQFPNEKIGFVS
                     SVTEDRLEQVQAFRDGELTILISTTILERGVTFPCVDVFVVEANHRLFTKSSLIQIGG
                     RVGRSMDRPTGDLLFFHDGLNASIKKAIKEIQMMNKEAGL"
     gene            47459..48121
                     /locus_tag="ACL3EZ_000669"
     CDS             47459..48121
                     /locus_tag="ACL3EZ_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HGR0392280.1"
                     /translation="MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEEN
                     CPNCMKTELSTKCQDCQLWCKEGVEVSHRAIFTYNQAMKDFFSRYKFDGDFLLRKVFA
                     SFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
                     KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSL
                     VR"
     gene            48201..48749
                     /gene="raiA"
                     /locus_tag="ACL3EZ_000670"
     CDS             48201..48749
                     /gene="raiA"
                     /locus_tag="ACL3EZ_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000599099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0045182 - translation regulator activity
                     [Evidence IEA];
                     GO_process: GO:0009386 - translational attenuation
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HGR0392281.1"
                     /translation="MIKYSIRGENLEVTEAIRDYVVSKLEKIEKYFQPEQELDARINL
                     KVYREKTAKVEVTIPLGSITLRAEDVSQDMYGSIDLVTDKIERQIRKNKTKIERKNKN
                     KVATGQLFTDALVEDSNIVQSKVVRSKQIDLKPMDLEEAILQMDLLGHDFFIYVDVED
                     QTTNVIYRREDGEIGLLEVKES"
     gene            48885..50858
                     /locus_tag="ACL3EZ_000671"
     CDS             48885..50858
                     /locus_tag="ACL3EZ_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HGR0392282.1"
                     /translation="MKKFYVSPIFPILVGLIAFGVLSTFIIFVNNNLLTVLILFLFVG
                     GYVFLFKKLRVHYTRSDVEQIQYVNHQAEESLTALLEQMPVGVMKLNLSSGEVEWFNP
                     YAELILTKEDGDFDLEAVQTIIKASVGNPSTYAKLGEKRYAVHMDASSGVLYFVDVSR
                     EQAITDELVTSRPVIGIVSVDNYDDLEDATSESDISQINSFVANFISEFSEKYMMFSR
                     RVSMDRFYLFTDYTVLEGLMNDKFSVIDAFREESKQRQLPLTLSMGFSYGDGNHDEIG
                     KVALLNLNLAEVRGGDQVVVKENDETKNPVYFGGGSAASIKRTRTRTRAMMTAISDKI
                     RSVDQVFVVGHKNLDMDALGSAVGMQLFASNVIENSYALYDEEQMSPDIERAVSFIEK
                     EGVTKLLSVKDAMGMVTNRSLLILVDHSKTALTLSKEFYDLFTQTIVIDHHRRDQDFP
                     DNAVITYIESGASSASELVTELIQFQNSKKNRLSRMQASVLMAGMMLDTKNFTSRVTS
                     RTFDVASYLRTRGSDSIAIQEIAATDFEEYREVNELILQGCKLGSDVLIAEAKDTKCY
                     DTVVISKAADAMLAMSGIEASFVLAKNTQGFISISARSRSKLNVQRIMEELGGGGHFN
                     LAAAQIKDVTLLEAGEKLTEIVLNEIKEKEKEE"
     gene            50855..51307
                     /gene="rplI"
                     /locus_tag="ACL3EZ_000672"
     CDS             50855..51307
                     /gene="rplI"
                     /locus_tag="ACL3EZ_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HGR0392283.1"
                     /translation="MKVIFLADVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEATAQAV
                     GELRGKQKSEEKAHAEMIAEGKAIKAQLEAEETVVEFVEKVGPDGRTFGSITNKKIAE
                     ELQKQFGIKIDKRHIQVQAPIRAVGLIDVPVKIYQDITSVINLRVKEG"
     gene            51351..52703
                     /gene="dnaB"
                     /locus_tag="ACL3EZ_000673"
     CDS             51351..52703
                     /gene="dnaB"
                     /locus_tag="ACL3EZ_000673"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HGR0392284.1"
                     /translation="MAEVEELRVQPQDILAEQSVLGAIFIDESKLVFVREYIESRDFF
                     KYAHRLIFQAMVDLSDRGDAIDATTVRTILDNQGDLQNIGGLSYLVEIVNSVPTSANA
                     EYYAKIVAEKAMLRRLIAKLTESVNQAYEASQPADEIIAQAEKGLIDVSENANRSGFK
                     NIRDVLNLNFGNLEARSQQTTDITGIATGYRDLDHMTTGLHEEELIILAARPAVGKTA
                     FALNIAQNIGTKLDKTVAIFSLEMGAESLVDRMLAAEGLVESHSIRTGQLTDEEWQKY
                     TIAQGNLANASIYIDDTPGIRITEIRSRSRKLAQETGNLGLILIDYLQLITGTGRENR
                     QQEVSEISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYERGGEEEEGIPNNKVEVIIEKNRSGARGTVELIFQKEYNKFSSISKREA
                     "
     gene            52705..52971
                     /locus_tag="ACL3EZ_000674"
     CDS             52705..52971
                     /locus_tag="ACL3EZ_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001278167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HGR0392285.1"
                     /translation="MSDAFTDVAKMKKIKEEIKAHEGQVVEMTLENGRKRQKNRLGKL
                     IEVYPSLFIVEFGDVEGDKQVNVYVESFTYSDILTEKNLIHYLD"
     gene            53060..54406
                     /gene="cbpD"
                     /locus_tag="ACL3EZ_000675"
     CDS             53060..54406
                     /gene="cbpD"
                     /locus_tag="ACL3EZ_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase CbpD"
                     /protein_id="HGR0392286.1"
                     /translation="MKILPFIARGTSYYLKMSVKKLVPFLVVGLMLAAGDSVYAYSRG
                     NGSIARGDDYPAYYKNGSQEIDQWRMYSRQCTSFVAFRLSNVNGFEIPAAYGNANEWG
                     HRARREGYRVDNTPTIGSITWSTAGTYGHVAWVSNVMGDQIEIEEYNYGYTESYNKRI
                     IKANTMTGFIHFKDLDGGSVGNSQSSTSTGGTHYFKTKSAIKTEPLVSATVIDYYYPG
                     EKVHYDQILEKDGYKWLSYTAYNGSYRYVQLEAVNKNPLGNSVLSSTGGTHYFKTKSA
                     IKTEPLVSATVIDYYYPGEKVHYDQILEKDGYKWLSYTAYNGSRRYIQLEGVTSSQNY
                     QNQSGNISSYGSNNSSTVGWKKINGSWYHFKSNGSKSTGWLKDGSSWYYLKLSGEMQT
                     GWLKENGSWYYLGSSGAMKTGWYQVSGKWYYSYSSGALAVNTTVDGYRVNSDGERV"
     regulatory      54489..54591
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            54662..54952
                     /locus_tag="ACL3EZ_000676"
     CDS             54662..54952
                     /locus_tag="ACL3EZ_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000647657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MTH1187 family thiamine-binding protein"
                     /protein_id="HGR0392287.1"
                     /translation="MKASIALQVLPLAQGIDRIAVIDQVIAYLQTQEVTMVVTPFETV
                     LEGEFDELMRILKEALEVAGQEADNVFANVKINVGEILSIDEKLEKYTETPH"
     gene            54915..55673
                     /locus_tag="ACL3EZ_000677"
     CDS             54915..55673
                     /locus_tag="ACL3EZ_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009013602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0392288.1"
                     /translation="MRNLRSILRRHISLLGFLGVLSIWQLAGFLKLLPKFILPTPLEI
                     LQPFVRDREFLWHHSWATLRVALLGLILGVLIACLMAVLMDSLTWLNDLIYPMMVVIQ
                     TIPTIAIAPILVLWLGYGILPKIVLIILTTTFPIIVSILDGFRHCDKDMLTLFSLMRA
                     KPWQILWHFKIPVSLPYFYAGLRVSVSYAFITTVVSEWLGGFEGLGVYMIQSKKLFQY
                     DTMFAIIILVSIISLLGMKLVDISEKYVIKWKRT"
     gene            55711..56718
                     /locus_tag="ACL3EZ_000678"
     CDS             55711..56718
                     /locus_tag="ACL3EZ_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGR0392289.1"
                     /translation="MKKTWKVFLTLVTALVAVVLVACGQGTASKDNKEAELKKVDFIL
                     DWTPNTNHTGLYVAKEKGYFKEAGVDVDLKLPPEESSSDLVINGKAPFAVYFQDYMAK
                     KLEKGAGITAVAAIVEHNTSGIISRKSDNVSSPKDLVGKKYGTWNDPTELAMLKTLVE
                     SQGGDFEKVEKVPNNDSNSITPIANGVFDTAWIYYGWDGILAKSQGVDANFMYLKDYV
                     KEFDYYSPVIIANNDYLKDNKEEARKVIQAIKKGYQYAMEHPEEAADILIKNAPELKE
                     KRDFVIESQKYLSKEYASDKEKWGQFDAARWNAFYKWDKENGILKEDLTDKGFTNEFV
                     K"
     gene            56718..57446
                     /locus_tag="ACL3EZ_000679"
     CDS             56718..57446
                     /locus_tag="ACL3EZ_000679"
                     /EC_number="7.6.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0392290.1"
                     /translation="MTEIRLEHVSYAYGQERILEDINLQVTSGEVVSILGPSGVGKTT
                     LFNLIAGILEVQSGRIVLDGEENPKGRVSYMLQKDLLLEHKTVLGNIILPLLIQKVDK
                     AEAISRADKILATFQLTAVRDKYPHELSGGMRQRVALLRTYLFGHKLFLLDEAFSALD
                     EMTKMELHAWYLEIHKQLQLTTLIITHSIEEALNLSDRIYILKNRPGQIVSEIKLDWS
                     EDEDKEVQKIAYKRQILAELGLDK"
     gene            57565..58023
                     /locus_tag="ACL3EZ_000680"
     CDS             57565..58023
                     /locus_tag="ACL3EZ_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HGR0392291.1"
                     /translation="MRFKNTSDHIEAYIKAILDQSGIVELQRSQLADTFQVVPSQINY
                     VIKTRFTESRGYLVESKRGGGGYIRIGRIEFSSHHEMLRDLLYSIGERVSQEIYEDIL
                     QLLVEQELMTKQEMNLLESVALDRVLGEEAPVVRANMLRQVIQEVDRKGK"
     gene            58025..60457
                     /locus_tag="ACL3EZ_000681"
     CDS             58025..60457
                     /locus_tag="ACL3EZ_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001109706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HGR0392292.1"
                     /translation="MNYSKALNECIESAYMVAGHFGARYLESWHLLIAMSNHSYSVAG
                     ATLNDYPYEMDRLEEVALELTETDYSQDETFTELPFSRRLQVLFDEAEYVASVVHAKV
                     LGTEHVLYAILHDGNALATRILERAGFSYEDKKDQVKIAALRRNLEERAGWTREDLKA
                     LRQRHRTVADKQNSMANMMGMPQTPSGGLEDYTHDLTEQARSGKLEPVIGRDKEISRM
                     IQILSRKTKNNPVLVGDAGVGKTALALGLAQRIASGDVPAEMAKMRVLELDLMNVVAG
                     TRFRGDFEERMNNIIKDIEEDGQVILFIDELHTIMGSGSGIDSTLDAANILKPALARG
                     TLRTVGATTQEEYQKHIEKDAALSRRFAKVTIEEPSVADSMTILQGLKATYEKHHRVQ
                     ITDEAVETAVKMAHRYLTSRHLPDSAIDLLDEAAATVQNKAKYVKADDSDLSPADKAL
                     MDGKWKQAAQLIAKEEEVPVYKDLVTESDILTTLSRLSGIPVQKLTQTDAKKYLNLEA
                     ELHKRVIGQDQAVSSISRAIRRNQSGIRSHKRPIGSFMFLGPTGVGKTELAKALAEVL
                     FDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVE
                     KAHPDIFNVLLQVLDDGVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDI
                     RFDQENMEKRMFEELKKAYRPEFINRIDEKVVFHSLSSDHMQEVVKIMVKPLVASLAE
                     KGIDLKLQASALKLLANQGYDPEMGARPLRRTLQTEVEDKLAELLLKGDLVAGSTLKI
                     GVKAGQLKFDIA"
     gene            60778..61431
                     /gene="rr06"
                     /locus_tag="ACL3EZ_000682"
     CDS             60778..61431
                     /gene="rr06"
                     /locus_tag="ACL3EZ_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001024075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RR06"
                     /protein_id="HGR0392293.1"
                     /translation="MNILVADDEEMIREGIAAFLTEEGYHVIMAKDGQEVLEKFQDLP
                     IHLMVLDLMMPRKSGFEVLKEINQKHDIPVIVLSALGDETTQSQVFDLYADDHVTKPF
                     SLVLLVKRIKALIRRYYVIEDIWRYQDVTVDFTSYKAHYKNEEIDLKPKELLVLKCLI
                     QHKNQVLSREQILEEISKDVADLPCDRVVDVYIRTLRKKLALDCIVTVKNVGYKISL"
     gene            61428..62759
                     /gene="hk06"
                     /locus_tag="ACL3EZ_000683"
     CDS             61428..62759
                     /gene="hk06"
                     /locus_tag="ACL3EZ_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     HK06"
                     /protein_id="HGR0392294.1"
                     /translation="MIKNPKLLTKSFLRSFAILGGVGLVIHIAIYLTFPFYYIQLEGE
                     KFNESARVFTEYLKTKTSDEIPSLLQSYSKSLTISAHLKRDIVDKRLPLVHDLDIKDG
                     KLSNYIVMLDMSVSTADGKQVTVQFVHGVDVYKEAKNILLLYLPYTFLVTIAFSFVFS
                     YFYTKRLLNPLFYISEVTSKMQDLDDNIRFDESRKDEVGEVGKQINGMYEHLLKVIHE
                     LESRNEQIVKLQNQKVSFVRGASHELKTPLASLRIILENMQHNIGDYKDHPKYIAKSI
                     NKIDQMSHLLEEVLESSKFQEWTECRETLTVKPVLVDILSRYQELAHSIGVTIENQLT
                     DATRVVMSLRALDKVLTNLISNAIKYSDKNGRVIISEQDGYLSIKNTCAPLSDQELEH
                     LFDIFYHSQIVTDKDESSGLGLYIVNNILESYQMDYSFLPYEHGMEFKISL"
     gene            62842..63369
                     /locus_tag="ACL3EZ_000684"
     CDS             62842..63369
                     /locus_tag="ACL3EZ_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HGR0392295.1"
                     /translation="MVLAIILVTFFIRLIFLKRSIENEKRILSNGGKEFGVENTKRLT
                     MAHIVFYLSCLVEAMVHKTIFDGMGMVGLVLLIFSMLMLMLVIHLLGDIWTVKLMLVN
                     NHKYVDHILFRTVKHPNYFLNILPELIGLTLLSHAYVTFVLVFPVYAVILYRRIAEEE
                     KLLHEVIIPNGSIKR"
     gene            63448..65631
                     /gene="pspC"
                     /locus_tag="ACL3EZ_000685"
     CDS             63448..65631
                     /gene="pspC"
                     /locus_tag="ACL3EZ_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal surface protein PspC,
                     choline-binding form"
                     /protein_id="HGR0392296.1"
                     /translation="MFASKSERKVHYSIRKFSVGVASVVVASLFLGGVVHAEGVRSGD
                     TPKVTSSGQDISKKYADEVKSHLEKILSEIQLDKRKHTQNLAFNKKLSRIQTEYFYLK
                     KKLKAELTSKTKEELTSKTEELTSKTKKELDAAFEQFKKDTLSTEPEKKVAEAQKKVA
                     EAKKKVAEAKKKAEDQKEEDRRNYPTNTYKTLELEIAEFDVKVKEAELELLKEKAKES
                     RDEEKIKQAEAEVESKQAEATRLENIKTDRKKAEEAKRKADAKLKEANVATSDQGKPK
                     GWAKRGVPGELATPDKKENDAKSSDSSVGEETLPSSSLKSGKKVAEAEKKVEEAEKKA
                     KDQKEEDRRNYPTNTYKTLELEIAESDVKVKEAELELVKEEAKEPRDEEKIKQAKAEV
                     ESKQAEATRLEKIKTDRKKAEEEAKRKAAEEDKVKEKPAEQPQPAPAPQPEKPAPKPE
                     KPAPAPKPENPAEQPKAEKPADQQAEEDYARRSEEEYNRLTQQQPPKTEKPAQPSTPK
                     TGWKQENGMWYFYNTDGSMATGWLQNNGSWYYLNSNGAMATGWLQNNGSWYYLNANGS
                     MATGWLQNNGSWYYLNANGSMATGWLQNNGSWYYLNANGDMATGWLQNNGSWYYLNAN
                     GDMATGWLQNNGSWYYLNSNGAMVTGWLQNNGSWYYLNANGDMATGWVKDGDTWYYLE
                     ASGAMKASQWFKVSDKWYYVNGSGALAVNTTVDGYGVNANGEWVN"
     gene            complement(65861..66841)
                     /gene="dusB"
                     /locus_tag="ACL3EZ_000686"
     CDS             complement(65861..66841)
                     /gene="dusB"
                     /locus_tag="ACL3EZ_000686"
                     /EC_number="1.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0017150 - tRNA dihydrouridine synthase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HGR0392297.1"
                     /translation="MTNLNTPFMIGNVEIPNRTVLAPMAGVTNSAFRTIAKELGAGLV
                     VMEMVSDKGIQYNNEKTLHMLHIDEGENPVSIQLFGSDEDSLARAAEFIQENTKTDIV
                     DINMGCPVNKIVKNEAGAMWLKDPDKIYSIINKVQSVLDIPLTVKMRTGWADPSLAVE
                     NALAAEAAGVSALAMHGRTREQMYTGHADLETLYKVAQALTKIPFIANGDIRTVQEAK
                     QRIEEVGADAVMIGRAAMGNPYLFNQINHYFETGEILPDLTFEDKMKIAYEHLKRLIN
                     LKGENVAVREFRGLAPHYLRGTSGAAKLRGAISQASTLAEIEALLQLEKA"
     gene            complement(66828..67700)
                     /gene="hslO"
                     /locus_tag="ACL3EZ_000687"
     CDS             complement(66828..67700)
                     /gene="hslO"
                     /locus_tag="ACL3EZ_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000357853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HGR0392298.1"
                     /translation="MDKIIKTISESGAFRAFVLDSTETVRTAQEKHQTQASSTVALGR
                     TLIASQILAANEKGNTKLTVKVLGSSSLGAIITVADTKGNVKGYVQNPGVDIKKTATG
                     EVLVGPFVGNGQFLVITDYGTGNPYNSITPLISGEIGEDLAFYLTESQQTPSAVGLNV
                     LLDEEDKVKVAGGFLVQVLPGAKKEEIARFEKRIQEMPAISTLLESDDHIEALLKAIY
                     GDEAYKRLSEEEIRFQCDCSHERFMNALASLPSSDLQEMKEEDHGAEITCQFCQTTYN
                     FDEKDLEELIRDKS"
     gene            67865..69292
                     /locus_tag="ACL3EZ_000688"
     CDS             67865..69292
                     /locus_tag="ACL3EZ_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGR0392299.1"
                     /translation="MYLGDLMEKAECGQFSILSFLLQESQTTVKAVMEETGFSKATLT
                     KYVTLLNDKALDSGLELAIHSEDENLRLSIGAATKGRDIRSLFLESAVKYQILVYLLY
                     HQQFLAHQLAQELVISEATLGRHLAGLNQILSEFDLSIQNGRWRGPEHQIRYFYFCLF
                     RKVWSSQEWEGHMQKPERKQEIANLEEICGASLSVGQKLDLVLWAHISQQRLRVNACQ
                     FQVIEEKMRGYFDNIFYLRLLRKVPSFFAGQHIPLGVEDGEMMIFFSFLLSHRILPLH
                     TMEYILGFGGQLADLLTQLIQEMKKEELLGDYTEDHVTYELSQLCAQVYLYKGYILQD
                     RYKYQLENRHPYLLMEHDFKETAEEIFHALPAFQQGTDLDKKILWEWLQLIEYMAENG
                     GQHMRIGLDLTSGFLVFSRMAAILKRYLEYNRFITIEAYDPSRHYDLLVTNNPIHKKE
                     QTPVYYLKNDLDMEDLAGIRQLLFT"
     gene            69451..70959
                     /gene="glpK"
                     /locus_tag="ACL3EZ_000689"
     CDS             69451..70959
                     /gene="glpK"
                     /locus_tag="ACL3EZ_000689"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004370 - glycerol kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006072 - glycerol-3-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HGR0392300.1"
                     /translation="MSQEKYIMAIDQGTTSSRAIIFNKKGEKVSSSQKEFTQIFPQAG
                     WVEHNANEIWNSVQSVIAGAFIESGVKPNQIEAIGITNQRETTVVWDKKTGLPIYNAI
                     VWQSRQTAPLAEQLKSQGYVEKFHEKTGLIIDAYFSATKVRWILDHVEGAQERAEKGE
                     LLFGTIDTWLVWKLTDGAAHVTDYSNAARTMLYNIKELKWDDEILEILNIPKAILPEV
                     RSNSEIYGKTAPFHFYGGEVPISGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNT
                     GEEMQLSENNLLTTIGYGINGKVYYALEGSIFIAGSAIQWLRDGLRMVENSPESEKYA
                     RDSHNNDEVYVVPAFTGLGAPYWNQNARGSVFGLTRGTSKEDFIKATLQSIAYQVRDI
                     IDTMQVDTQTAIQVLKVDGGAAMNNFLMQFQADILGIDIARAKNLETTALGAAFLAGL
                     SVGYWKDLDELKLLNETGELFEPSMNESRKEQLYKGWKKAVKATQVFAEVDD"
     gene            71001..72827
                     /gene="glpO"
                     /locus_tag="ACL3EZ_000690"
     CDS             71001..72827
                     /gene="glpO"
                     /locus_tag="ACL3EZ_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004368 - glycerol-3-phosphate
                     dehydrogenase (quinone) activity [Evidence IEA];
                     GO_process: GO:0006072 - glycerol-3-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HGR0392301.1"
                     /translation="MEFSKKTRELSIKKMQERTLDLLIIGGGITGAGVALQAAASGLE
                     TGLIEMQDFAEGTSSRSTKLVHGGLRYLKQFDVEVVSDTVSERAVVQQIAPHIPKPDP
                     MLLPVYDEDGATFSLFRLKVAMDLYDLLAGVSNTPTANKVLSKKEVLERQPNLKKEGL
                     VGGGVYLDFRNNDARLVIENIKRANQDGALIANHVKAEGFLFDESGKITGVVARDLLT
                     DQVFEIKARLVINTTGPWSDKVRNLSNKGTQFSQMRPTKGVHLVVDSSKIKVSQPVYF
                     DTGLGDGRMVFVLPRENKTYFGTTDTDYTGDLEHPKVTQEDVDYLLGIVNNRFPESNI
                     TIDDIESNWAGLRPLIAGNSASDYNGGNNGTISDESFDNLIATVESYLSKEKTREDVE
                     SAVSKLESSTSEKYLDPSAVSRGSSLDRDDNGLLTLAGGKITDYRKMAEGAMERVVDI
                     LKAEFDRSFKLINSKTYPVSGGELNPANVDSEIEAFAQLGVSRGLDSKEAHYLANLYG
                     SNAPKVFALAHSLEQAPGLSLADTLSLHYAMRNELTLSPVDFLLRRTNHMLFMRDSLD
                     SIVEPILDEMGRFYDWTEEEKATYRADVKAALAQNDLAELKN"
     gene            72895..73599
                     /locus_tag="ACL3EZ_000691"
     CDS             72895..73599
                     /locus_tag="ACL3EZ_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MIP/aquaporin family protein"
                     /protein_id="HGR0392302.1"
                     /translation="MMSELFGEFLGTLILILLGNGVVAGVVLPKTKSNSAGWIVITMG
                     WGIAVAVAVFVSGKLSPAHLNPAVTVGVALKGDLPWASVLPYILAQFAGAMLGQILVW
                     LQFKPHYEAEENAGNILATFSTGPAIKDTVSNLISEILGTFVLVLTIFALGLYDFQAG
                     IGTFAVGTLIVGIGLSLGGTTGYALNPARDLGPRIMHSILPIPNKGDGDWSYAWIPVV
                     GPVIGAALAVLVFSLF"
     gene            73896..74099
                     /locus_tag="ACL3EZ_000692"
     CDS             73896..74099
                     /locus_tag="ACL3EZ_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0392303.1"
                     /translation="MPKWSNPDYVNELDPKIVDMLVEFHKSQGTLETPEAQAEIAQKR
                     EEIEQRRAELEDKKQELLNRLNK"
     gene            complement(74186..74794)
                     /locus_tag="ACL3EZ_000693"
     CDS             complement(74186..74794)
                     /locus_tag="ACL3EZ_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0392304.1"
                     /translation="MSSISPSLVVFADDSLSANSKVVSGEAQFENGSSVRFGDTQVNI
                     LSDEVLEVVNPDGSVDTIERRADGVYINGAFYMAYQKNEIDLNISFRSYDPNVWNYVN
                     TIHGNKQANTFANFMTGAGISYMIGRIGALLGGPWGAIIGGAYFGIQAYQSYLDSQSP
                     YPYYITSTYIHVAQRKWKFITEYYRNSNYTGYVKTVTTYVNF"
     gene            74926..75123
                     /locus_tag="ACL3EZ_000694"
     CDS             74926..75123
                     /locus_tag="ACL3EZ_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000930586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0392305.1"
                     /translation="MLNAKIFYIFLCLIVIETTGLLLLKRGLEMGYLDTEAIILAVFS
                     FAFYNLCSFAWVCSTIKNNKK"
     gene            75828..>77038
                     /gene="ltrA"
                     /locus_tag="ACL3EZ_000695"
     CDS             75828..>77038
                     /gene="ltrA"
                     /locus_tag="ACL3EZ_000695"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003964 - RNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0000373 - Group II intron splicing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HGR0392306.1"
                     /translation="MSKLLDKILSRENMLEAYNQVKSNKGSAGIDGMTIEEMDNYLRQ
                     NWRLTKELIKQRKYKPQPVLKVEIPKPDGGIRQLGIPTVMDRMIQQAIVQVMSPICEP
                     HFSDTSYGFRPNRSCEKAIMKLLEYLNDGYEWIVDIDLEKFFDTVPQDRLMSLVHNII
                     EDGDTESLIRKYLHSGVIINGQRYKTLVGTPQGGNLSPLLSNIMLNELDKELEKRGLR
                     FVRYADDCVITVGSEAASKRVMYSVSRFIEKRLGLKVNMTKTKITRPRELKYLGFGFW
                     KSSDGWKSRPHQDSVRRFKFKLKKLTQRKWSIDLTRRIEQLNLSIRGWINYFSLGNMK
                     SIVASIDERLRTRLRVIIWKQWKKKSRRLWGLLKLGVPKWIADKVSGWGDHYQLVAQK
                     SVLKRAISKPVL"
BASE COUNT        23960 a        13455 c        15618 g        24005 t
ORIGIN      
        1 attttttttg catgacttac tagtgggtac ggatagtaaa ctccttaaac acaatgcgta
       61 agtctcttaa tactctttga cgccctcgaa atcgttcatt gcttaagacg cgttctagtt
      121 cttcttgttt ctctttactt tgtttgtttc tataatctct tagtgtttca tgaaagagat
      181 aataatcatc tagccagaga cccccctcac ttatacgatg actgatctca cccacttctt
      241 catagggttc tttatcgtat ctacgcttct gactttcctg cttacggata tagtctaaaa
      301 ttcgatttcg aaacttggtt ttgaaatatt tccttaaacg tggaatatcg tctaccagtc
      361 cttcttctct actaatcaat tcatgtaagc agagcatgcc ttcttggtcc caatccgaca
      421 attcccataa atgaaggtaa tattcatttc tacacttata cacagtccct tggacttctt
      481 catacaattc tttaatcata attttcccct ttctagatac agtctaacag attagaaaac
      541 acatttgttc cattttctcc attctgttcc ctttagctcc taaactgcac aaaaaagaga
      601 ggctccagcc tctctcaggg ttatttttcg tcattcattt ttgactttac ttcatcatag
      661 gatagtgcat gagattcctc ttctactgct tcaggcatct ttcctgtttc gtaaagagct
      721 ttaatttgtg tactatccaa tgtttcgtat ttcaataatg cttctgcaat taacttgtga
      781 gtttcacgat ttgactgaat aatttcagca gctttatttc gtgcctcatt taataatgaa
      841 cgaacctctt catcaatttc ataagctgtt tgttctgaaa ttgatttttg aggattctgt
      901 gcaccaaaca tagcatggtt tccttcatat tgtactgggc caagtttttc actcataccg
      961 tactctgtaa ccattgcacg tgccatttgt gtcgcttgtt caaagtcgtt tgaagctcct
     1021 gtagtttgga cattaaagat aatttcttca gctacacgtc cacccattaa gccagccaat
     1081 tgctctttca tatcttcttt agatagaagc atttgatcct ctttaggaag tgcaatcatg
     1141 tatccgcctg cacggccgcg tggtacaatt gtaaccttat ggacaacgcg agcattcgac
     1201 aagactagac caacaatggt atgtcctgcc tcatggtaag caaccaattc tcgttctttt
     1261 tgtgaaactg tcttatcttt cttagaaggt ccagcaataa ctctatcttc tgcttcatca
     1321 atatctgaag catcaattat cgatttattg cgacgagcag caactaaagc tgcttcattc
     1381 aagacattct ctaaatcagc accaacaaag cctggagttt gttgagccac taatttcaaa
     1441 tcaacatctt ctgctaaagg cttgttctta gcgtgaactt tcaagattgc ttcacgacct
     1501 ttaacatcag gacggccaac caatactttt ctatcaaaac gtcctggacg caaaagggca
     1561 ggatcaagta catctgaacg gtttgtcgca gcgatgacga taatcccttc atttccctca
     1621 aaaccatcca tctcaatcaa aagttggttc aaggtttgtt cacgttcgtc attacctccg
     1681 ccgagaccga ctccacgttg acgtccaaca gcatcaattt catcgataaa gatgatagct
     1741 ggtgctgctt ttttggcatc ctcaaaaaga gagcgaacac gactagctcc aactccgaca
     1801 aacatttcta caaagtcaga acctgagata ctaaagaatg gaacacctgc ttctccagcg
     1861 actgccttag caagcaaagt tttacctgtc cccggaggtc cctccaaaag aacacctgct
     1921 ggaatacggg ctccaagttt tgtgaatcgt tttggatctt ttaagaactc aacaacttca
     1981 actagttctt gtttttcttc ttcagctcca gcaacatctg aaaatcttac tttaatatct
     2041 tctttatttg ctgctttagc cttactacgt ccaaaactca ttggattacg gccattgcct
     2101 cctcccatat ttcccatcat agagaatagg aagaagaata gaattccaaa tggcacaatg
     2161 gatacgagta gattaatcca tataccactt gaactttcat gcttaacagt tacttctgct
     2221 ttatggtcag tagcaagttt ttgcaattct gatacggtag tatctgcagg aagaatagtg
     2281 ctggtaaatt tctctacctt agtaacagat ggcgtgaaaa actgaatacc tgttccttct
     2341 ttacttgttt taggattttt atagacacca gaaacttcga taacactacc atttggttgg
     2401 taagttaatt cttttacatt accatcggta atttcttgta ccaactcagt atagttgatt
     2461 tgctgacttc ctcctgagtt attcccagaa tagaaatact ggaatcctgt cacaaggaaa
     2521 aagataaata ataaccatag aaaaggattt ttaattaaac cattattttg ttttttcatt
     2581 aaagattatt ctttctaatt tgaatacact tcctctttca atactccaat ataaggaaga
     2641 ttacgataat tttctttgta gtctaaacca taacctacta caaactcatt tgggatagta
     2701 aagcaggtat agtctgcctc aatttctaca acacgtcctt ctggtttatc caacaaggtt
     2761 gcaattttaa cagaagctgc ttctctttct ttaaacatat ctcgcaaatt cttcaaagtt
     2821 tgacctgtat caatgatatc ttctacaaat agaacatgtc ttcctttgat atcttgagtc
     2881 acatcttgtt taatattgat aacaccacta cttgctgttc caccatggta gctagaaacc
     2941 atcatgaagt ccatttcaat atgtgtatca atatgtttga ccaattcagc cataaaagga
     3001 atagatcctt ttaaaatccc aactaagatt ggattttttc ctgcatagtc tttagttaat
     3061 tgagcaccta gttttttagc tgcttctgta atttcatcgt gtgaaacgag gactttttta
     3121 atatcgtttt ctaacatttt ttacctatct attttttcta tataaagtac agtgttaatt
     3181 atatcatttt tcgttttttt actcaaatta ttggtcgcaa ttcccaaaat tgagacaatt
     3241 tcaccaaatt gctcaataat aagagcagag tttctctttt ccatagggat tttcaaatca
     3301 ataaataaac gtctgagttt ttttctatgc ccattttgaa tcaaaacatc tcctgttttt
     3361 cgatgacgaa tgtgtatgga tgtttcacgt gaaacaggta tttgttgaat taattcacct
     3421 tctaatggaa gtccaaagga aaataaatat ccttgataag ctacctgatt ttgatagtgt
     3481 aacacaagtt catcttcctt ttcatcagcc tgcggactga ttttacaaat ctgaaactgt
     3541 tggtactctt ttatcaattc atagccattt ttaatcggat gacgatactg gcttttagat
     3601 tttaaaatct gctgaacttc agcaaactga gcttttgtaa gattcaaatc tggaaaacga
     3661 ttcagataag tttgaagtaa aactctttgt gtagactcag agtaagaaaa taactgctgt
     3721 aaatcttcca cattaatatt gttagataat tcagctattg ccaaatcata atctaaaatt
     3781 tcattgccaa tgcctaagat tgcatcccta aatcgaggat tttctttttc caattctggt
     3841 aagtaagagt ttcgaatacg atttcgaaaa taatgattct cctgatttga tgtatcttca
     3901 aagtgaaaaa ttgatggaaa gtcttttttc tgaaaatgca agaagggacg aatgatttct
     3961 atctctccga ctacttgctt ctccttaatt cctgatagat agcgcaagcg agttcctcga
     4021 atcaagcgca tcaaaatcgt ttccacctga tcatcagcat ggtgggcagt gactaaagct
     4081 gtcgcacctg tctttttcat aacctcttga aaaaaatcat aacgaaaatt tcgtgcacgc
     4141 gcttctgaaa attctcctga aaaattgctg atataaatag gaagctctgc ttcagcagcc
     4201 aacttcctta attccttttc ttcccaatct gattcaattc tctgcttatg attcacatga
     4261 gctagaatca attcaatctc taactctttt tgataagtag acaatacctt aaatagaaac
     4321 atggaatcta atccaccaga aagagctaga accgccttag catgcttttt gaaatatccc
     4381 ttcttgagaa aatgatttaa aaaatctggt tccctcattt tagaacctca taaacatcct
     4441 tggctatctt agaaatcgta tcataatcag aattcttagt gaaaatagaa agaataaatg
     4501 gagaatctgc atagacaaca cccgtatcat gcttaaattc atccgcatct ccaattttat
     4561 gagctacttt aacagaaaca cctttggcaa ttcgctgact atcaaaatct gttttagtca
     4621 aagactctag cacaaatcca ttttgattat aaatagcttc cataaacttc ccggccatct
     4681 tagaagaaat caatttttct tttggatccc aatcatctcc cataatggca gacatcttgg
     4741 atttgaatgt ggcatcagat tggtttgaaa tgtaatatcc caatagatta tgagctacat
     4801 tatcagattc ttttgatact ttcgtaatta aatcctttaa agaatattct ttattatctt
     4861 cttttttagg aagactacca cttccctctg gtttataaga acctggaaaa tcattgactg
     4921 cagatacgta ttttacagtc gtatctaact gataaagacc ctcatttatt ttttcttgcg
     4981 tataatagag ataggagagt ttcaaaacgc tggctgcata catcttttca tcttgattga
     5041 taccagcttc ttttccagta gtcagttgct taacataaat agagaaagaa tctttctgat
     5101 atttttcaga taacatttct tgaactttac tcatccgatt atcttcttca gaagttgatt
     5161 ctttagctac ccatccagcc tgatcaatat gtagaaattc tcttccttct acaaacatgg
     5221 tcttgtcgat tgatacttgc gaataagctg ataaggatga tttcacttct tttaaatcat
     5281 aaggactatt gtacagttta aagtcagatt ctaaccatgc tttttttatt gttggagtta
     5341 cctctgattg atcatataaa aatcgtttgt ccgcagctat aaattgatga tttgatagct
     5401 taaatactgg aattccttgt ttatttaagc gccactcggt tatttgaaaa cttgttttgg
     5461 gagtcaattt cccagattcc actactaaat cttcattcgc ataaacagga acctctccat
     5521 aaaccatggg agaacttaat ttttctctaa aataaatact aaagtcagat tgtgaaaggt
     5581 aataaatttc tttcgaagta tagacgactt ctttttctgt gctaacgact tttgaaatgg
     5641 tcaaaaaact tggtagcaac aaaataatta agaatttacg cattcttcct ttccttttct
     5701 tcttgtaaac gcaataattg atttttatca gccaattctt ccagcttttc atctgacaaa
     5761 ctcaaaaatt gctctattac gtctaataaa ttttccattt tatcaccttt gaagcaagtc
     5821 aggaatcgta taaacttttt ccctcgactt agaataatag tacttcgctc gtgtatattt
     5881 agcagcataa tcttcatctt tcaacttggt agcaaatgct gtctccttat ccttttcatc
     5941 actcaaagtt tgatactgag tttgcaagtc tgctaattgc tgacgtcttt ggagtaattg
     6001 ctgataactc tgcgctaaat taaaagttgg caagataaat aatagcataa tcaaaatcaa
     6061 tacccctccc ataaaacgat tccgtttttg tcgttctttc atcaggtagc gacgacgttg
     6121 gtattcattt tgaataaaag aattattcaa ttgtacaata tttttagaca ttttcttcta
     6181 cccgtgtttc actgataatt tcatacattc ctgctgcatc ttcttttttt gtactatctt
     6241 tcatctctag tacttttaca agcagcaact tattgccaaa gcgaatttca acttggtcat
     6301 taactttcaa gtccgttgaa cttttggcca agattccatt aaccttgatt ctacctttat
     6361 ctgctacttc ctttgcgact gtacgacgct tgataattcg cgatactttt aaatatttat
     6421 ctaatctcat ccttattacc tcaatttatt attgtaccat ttttatctat tttatagaag
     6481 aaaaatatca aatggaattt tcttccttaa actcttttat ctctaataaa ctttctccaa
     6541 aaatcagcag accttctaaa atttcataat ctttcttatt ttggacatca aatacaagct
     6601 ccattaatcc cttattctca gcgatgcctg cttttaagtt cgttacggat aaagctttaa
     6661 aataatcttg agctaaaaac agccgttgag tgactttttc aaattgaatt gtaattttat
     6721 tatcttttct ttccacacgt tgaacaaaga ccttgtccaa gtatgattta accaaaccaa
     6781 tctctaaaag ataggctact acatctgggt attctccaaa acggtctatc aactcctctt
     6841 gtaactcttc ataattgaca cggttgtcaa tttgacgaat tttcttgtaa atttcaatct
     6901 tatgtcgttg atcagaaata taagtatcag gaagataggc atcaatttgc aaaatcaact
     6961 cagcattccc tttggttctt gtgttagcgt tagcattacc gtttcgttta gcaatagctt
     7021 cctctaataa ctgcgaatac aattcaaaac caacagaatc aatgaaacca gactgggatt
     7081 ttcctaaaag atttcctgct ccacgaatcg aaagatctcg cattgcaatc ttaaagccag
     7141 agcccaattc tgtaaatcct ttaatcgctt ctaatctctt ttcagagact tcactgattg
     7201 atttttctgg acgatacatg agataagcat aagcaatacg attactacga ccgactcttc
     7261 ctcttaactg atataaggtt gacaagccca tatggtccgc attttcaata aataaagtat
     7321 tagcatttgg aatgtccacc cctgtctcaa taatagtagt cgtcaccaag atatcgtatt
     7381 gtccctcaat aaagtctaat agagtatttt ccaactggac ttcactcatt cgaccatgaa
     7441 catatccaat cgaagcctcc ggaatcaact cctgtaattc tgaaaccttc tgaacaattg
     7501 tgtcaacttt gttgtaaaga taataaactt gacctccacg ctccatttca cgcaagacag
     7561 catcacgaat gacactatca ttcttttcca aaacataggt ctgaacagga tagcgattag
     7621 tcggcggagt ttcaataaca gataaatctc tgattcccag catagacata tggagggtac
     7681 gagggattgg cgtagcggtc aaggttagga catccacttg tttcttcagt tctttcaaag
     7741 tttccttatg cttgacacca aatcgctgtt cctcatcaat aatcatcaag cccaaatcag
     7801 caaacacaac atcttttgac aaaacacgat gtgttccaat caaaatatcg acttgaccgt
     7861 ttttcaattt ttcaagtgtt gcagtctgct cttttttact tctaaagcga ctcaacacat
     7921 caacattaac tgcaaaattt tggaatcgtt ccttaaaatt cgtatagtgc tgttgcgcta
     7981 aaaccgtcgt cggaactaga atgacaacct gtttgtgatc attgactgct ttaaaggctg
     8041 cacgcatagc aacttcagtc tttccaaaac caacatcccc aactaaaagt cgatccattg
     8101 gctgagaagc ctgcatatcc ctcttgattt cctcaatact acgaagttga tcatccgttt
     8161 caacataagg gaaagcatca tcaaaggcat cttgatcatc atcatcagct gagaaagcaa
     8221 aacccttcaa ctgactacgt tcagagtaga gtttgattaa atcatcagct atatcctcta
     8281 cctggttctt aaccttttgc ttggcctttt taaaatgacc gtcatttaat ttattgagtt
     8341 ttggagcttt accatcactt gaaatatatt tggacagtag atgaatctgt tccacgggga
     8401 tagaaatttg atcaccattt tggtattgga cactgacata atcgcgatga attcccttga
     8461 tttcaatggt ttcaattcct agatattgac caatcccatg gatatgatgg acaacatagt
     8521 cccctttttc aagttcattg taatctttta atctctctgc atttgaaaca tgttgtcttc
     8581 gaaaacgacg ctttaatttc ttttgaaaaa tctcatgttc agttatcaat aaaatctttt
     8641 catctacaaa atgaaaacca tgtctgagat taccctctat taagtttaca gattctttac
     8701 agatacttgt cttatctcta gaatccaatt taatctgata ttcctctaac atatcctcca
     8761 atgttttact tcccattgaa ttgctagact gcagaataat ggtgtaatcc atttttttat
     8821 atcgttcaat ttcttctttt agaaaagaaa actgattgaa aaattcctgc ataggatatt
     8881 gattaaattg ataaattttg tcaaatttga gatttcctaa acccttttga agattagaga
     8941 aaaaggtcac tggactttgt tttttataga tttgttcaat atcagaaaaa tactgcatat
     9001 cagaaaatgc tttactattc tgtaattctt ctgtaaagta ctgcgctaag tctctttcaa
     9061 agacttcata ctgattcatc aatttttgat aatcatcaaa gaatattgga gtatcttttt
     9121 caatataatc aaagacagtc catgtcttat catagcacaa agataaaaac ttccgagagt
     9181 ctgcatgact ttgtttttgg tgaaaacttg aaagaatttc ttctaggtat gatttcaaaa
     9241 taggtgataa agtttttgaa atttgttttt ctaaagctga ctgtcctcgt tgataatcct
     9301 tttctctcaa aagcatatca ctagctggaa agatagtgag ttctgtctta ttttctttcg
     9361 ataattgtgt ttctacttca aatgacctga taccatcaat ttcatcacca aaaaactcaa
     9421 ttcgacaagg ttctaactgg gatatttcaa aaatatctaa aatatctcct cgaagactaa
     9481 attcgccctg agtttgtact tgagtaactt ttcgatagcc attttccttt aactgatgga
     9541 taaacgcgtg ttgatcatat tcttcaccaa ctgagatttt tacaatacta tctttgaatg
     9601 cattgggaga cggtaaaatc aatcgacttg ctgcgatatt acaaactaaa atccctttct
     9661 tagatgaatc agtcaaaaaa cgcaaggctt caacccgtga aataattttt tcctgtgaag
     9721 acatcaaaaa ctccaccata ggagcatcat ctaccaaaaa tggatagacg agttcctcac
     9781 ccaagataga aataagatca ctaacaagtc cttctgcttc tccataagtt gacgtcaata
     9841 acacaatcct atcttctttt tctaaactgc ttgcaattgc aagagcctta gtagatgttg
     9901 ataaaccaag tattagttgt cttttcttat ctgttaaatt ttgatgccat tttttaatct
     9961 gatcattttc tgagaataaa tctaataagg tcaccattta tccgttatac ctctgcattg
    10021 ttttctcaaa atttttctct tgtaaatagt attttacaga atcgtcaact ttgtcaacag
    10081 actgtaaaat accgatataa tcatccctgt caaacttact caaaacatga tgaacaactg
    10141 acataccatt tttaggtctt ccaattccaa tcttaacacg gttaaagacc tgagttccta
    10201 tatgttgaat aatagacttg ataccattat gaccacctgc tgagcctttt gctcttaaac
    10261 gaattttccc aacttccatg tcaagatcat cgtaaatgat aagtaaatcg tcaatatcca
    10321 aaccatagta agttaataaa gcatgaactg cttttccact ttcattcata aaggtcgttg
    10381 gtttaaccag ataaattttt tctccattta ggaaaaagga tgctaggtca gcttgaaata
    10441 tcttatcgtg tgtaaaagtg acattctgtt tcttcgctag ttgatcaatc aacataaaac
    10501 caacattgtg ttttgtttca aaatatttat cccctggatt tcccaagcct acaagtaatt
    10561 tggtcattta tttttccttt caaaagccaa aagggttgga attttttttc caacctaatt
    10621 gacaccattt attaattttt agacattaaa gcggaattcc atgatatcgc catcttgaac
    10681 gatatattct tttccttctt cacgcaagcg tccagcttct tttacggcct tttcagatcc
    10741 gtatttcact agatcttcat atgacatggt tactgcacga ataaagcctt tttcaaagtc
    10801 tgagtggata ataccagctg cttgaggagc cttcatacca cgtttgaaag tccaagcgcg
    10861 aacttctttt tcaccagctg tgaagtaagt tcccaatcca agcaagtggt aagctgcacg
    10921 cgtcaactta tctacacctg attctgtcaa accaatggct tcaagaaact cttttttatc
    10981 ttcatcatcc aattcagaaa tttcttcctc agcacgcgca gaaataacga ctacttcagc
    11041 attttctgtc gctgcaaatt cacgaatttg tttgacatag tcgatagagt caggttctga
    11101 aaccacatcc tcgtccacat tagctacata aagaactggt ttagtcgtca aaaggaaaag
    11161 acctttgaca accttttgtt cctcatctgt aaattcaatg gtacgagctg atttcccgtc
    11221 ttctaggact ggtttaatct tttgaagaac attgaattct gctactgatt ctttatcttt
    11281 ttgcgtacgt gccatctttt ctacacgcgc atatcgtttg ttcactgatt ctaagtcagc
    11341 aagaatcaat tccagattaa ttgtatcaat atctgcaagt ggatctacaa aggcgtcttc
    11401 acgtccttgc tcgcgcatca cattttcatc atcaaaagca cgaactacgt gaacaatcgc
    11461 atctacttca cgaatattgg ccaagaattt attccctagc ccttctcctt ttgaagctcc
    11521 ttttacaatc cctgcaatat ctgtaaattc aaatgttgtg ggaactgtct ttttaggagt
    11581 tatcatttca gttagttttt gtaggcgttc atctggaact tccaccattc caacatttgg
    11641 atcaatagtc gcaaatgggt agtttgctgc ctctgctcct gcttttgtaa ttgcattaaa
    11701 taatgttgat ttaccaacgt ttggcaaacc aacgatacct gctgtcaaag ccatatttct
    11761 cattctccgt tttcatttca atccctaata ttataacaca aaaagggata aagtgctaac
    11821 cctctaacta agggttctca gtcaataatt ttattcattt ttcgctcaaa atcatatcgc
    11881 cccatcatga caacatgctc acaattactg cattttattt tgatatctgc tcctacacgt
    11941 gtaatttccc aacgattagc ctttttacca gtcgacttga ttgtacaagc gtgtgatttt
    12001 ttcatctcaa caaaatttcc aacttgatac atactactct ccttttcttt ttcgattata
    12061 tcataaaaga ggcgagccag gctcaacctc tttcacttaa tttgtacgaa ctggtgtaat
    12121 gagctgcatg aagtcttcgt cagtatctgc tggcacaaga gtaaatggac gaacagctga
    12181 gataaagcta atggtcacct tttcgctatt taaagcttta agagaatcaa tcaagtaagt
    12241 tgggttgaaa ctaatggtca aatcttcacc agtaacctga tcagtatcga tttcttcgtt
    12301 tactttacca acttctggag agtgaacatg ggcgctaaca accccatcct taatttcaag
    12361 tttcacagta ccattttgag tcgcacttga taaaagacgg gcacgctcca ttgactggcg
    12421 taagtttacc acattaaaag taatagtagt gttaaagtct gttggaatca agcgatctgt
    12481 atcaggatag tttccttcta ggagacgagt atagaagcta atattttcgc ttctaaagag
    12541 gatttggtta ttggcaaaga aaatctctac agtttcgata tcatctgtaa ataccgctga
    12601 aaattcgcgt agagaacggc taggaattac gacatcaaaa tcatcactat ttttttcaag
    12661 agtcaatttt ttctggctta ggcgatgaga gtctgttgca actgttttta actctttgtg
    12721 ttgactcaat acgaagtgga cacctgttaa aatcggacga ctctcttgtg tacttgcagc
    12781 aaaggctgtt tcattaataa ttttcttgag taattttgtt tcaagtatta aaggagtgct
    12841 tgctgaaatt tcttggattc gtggatattg ttcgctatct tttcctttta gggtaatttc
    12901 tgatttgcca ctggttaaaa caatttgatt ttgttcaatt tctttaaaat caagagtcac
    12961 atcaggtaaa ctagatacta cattgataaa gaaagaagct tcaagaagga tcgaacctaa
    13021 agaagtaatt aacaaaccag catcttcatt tttttgagaa ataaaatttt caattgaaat
    13081 ttgaccattt gaaccaatta aagtaatacc ttcattggtc acgtcaattt ttactgttga
    13141 taaaatagga atggcatttt tagaactaat agctctctta gtagtattta atgcttgtag
    13201 aaataaattt ttattaattg aaaaatgaat catggattct cctttattta tttttagtat
    13261 tagaaagata atagtaataa tagagtctgt gaaatctgtg gaaaacagcc tttaaacaag
    13321 tcatatcaag ttttttagct tgtttaaaaa atgtggataa aaaagataaa aaactaaaag
    13381 ttatccacaa attatttgat tttctttttg attgattcaa tttctaaacg taaattatcg
    13441 tcttgatcaa tcaaagattt tattttggca tgggcatgaa tgactgtggt atgatctttt
    13501 cccccaaatt ccttcccaat ttttggaaga ctattatctg ttagttctct agataaatac
    13561 atggctactt gacgggccaa aacaatattt tgaaggcgtc tacttccctt catttctttg
    13621 atactaacac cataaaagtt accaacttca gtttggattt tatcaattgg gatgacgagc
    13681 atttggctaa catcttgttt gcgggctcta atggcttctg cagcaatatc aatagtgata
    13741 tccttgattt tttttactct ggcaattaaa gtgatgtcgt tgatggctcc ctcaagatct
    13801 cgaacatttg aatcaaattg cccagctagg tattctagag tatcactttg gaaattgtag
    13861 cctaaatgtt ccgttttact ttgtaaaatg gcaatacgtg tttcaaagtc agggggtgtg
    13921 atagtttgtg tcaatcccca actaaaacgc gtgacaagcc tctcctcgag cccttctaga
    13981 tgttttggac tacgatcact cgttaggaca atctgttttt gcttgtcatg aagggcgtta
    14041 aaggtattga aaaattcttc ctgagttgcg actttttttc cgctgagtga ctgtatatca
    14101 tcgattaaca aaagatcaag actacgatag gtctttttaa acttttccat ttccccaagt
    14161 cttaggtgat caagaaagtc attaataaag ctttcggcag ggatatattt aacacgcgca
    14221 ttaggaatat tttttagaat ttcatttcca atagcgttta ataagtgagt cttaccaagg
    14281 cctggtcctc catagataaa aagagggtta taggtcagag ccaaatcttc agagacagct
    14341 aaagcggctg atacagccca aacatttcca tccccttgaa taaagttatc aaaggtatac
    14401 ttttctttta atcccgtatc tgaataagga atagatacta actttggact atagtcataa
    14461 agagttaaat ttgtagcttc ttcaacttgt gagctagtcg tatcttgagg tttggtgaaa
    14521 atatagtggg gagttatttc agcgtcataa atttcaaaac cagctactac aataatatct
    14581 tttagttgtt tttcccagac catttccatt tcagagcgag gtagaaatat agtggcaaca
    14641 ttttcctcta ccttgatgag ttcagcttga atagcataga aatcatacat ggatcgagtc
    14701 agtctttctt gtgcaaattc taatatacga ttccaaaatt gtttttcttt caatcctttc
    14761 tcctccttta ctatttaaaa gtttaatact agagatattt taccatagat agcaagaatt
    14821 ttccacaagc tgtgaaaaat aatccacaat gttactaaac tttatccaca ggttggggat
    14881 aaaagaagaa attattgatt tattaagctt tttatcgaaa aacatagtgg ataaccttgt
    14941 gagataaaaa aataaaagaa cagccttatt tcaggctgtt gataattcta ctatattctt
    15001 cttgatttga aaaagaaata atgatttttc cactgtcttt tttagatagt ttaatttcta
    15061 catctaatcc gagtagtttt cttaactgtt tttcttcatt ttgtatgaaa tgattagttt
    15121 tttgctgttt cttttgtttt ttctctgtca gaagagcttc taacttcctt acagaaatat
    15181 cttcttctat aatccgttga aagaaatagt cttgttgttc cttatttaac ccaactaggg
    15241 aacgcgcatg ggcttgtgat agtttgccat tttctacttc tgagagaatc tgttctggca
    15301 aggaaagtaa acgaatggag ttgctgatat atggacgaga cttgcccatc ttatctgcaa
    15361 tttcagcatg ggtgaatcct ttctctacga gagattcata ggcgcgtgct tcttctattg
    15421 ggtttaaatt ttctctctgt aaattttcaa taatggactg gaccatcatc tcttggtctg
    15481 aaatctgttt aacaacagct gggatagacc gtagaccagc taaaagtgaa gcccgatagc
    15541 gtctctctcc tgcaaggatt tcataaccaa taacaggaga ttgacgaaca ataatcggtt
    15601 gaatgacccc attttctttg atagactgtg ctagttcatc tagtttttct ctatcaaatt
    15661 cttttcgggg ttgataggga tttttttgta tatctgtgat agaaatcatt tcaaattttt
    15721 ccatgattct acactaacac atcttttctc ttatgtaaag ctttctttac atagatgtca
    15781 attaagattc taaatcacct gaactcttgt taagtttgat agaggtagtt tcttctttcc
    15841 cgttacgata gtaggttatc ttaatggtgt ctccgataga atggttgtaa agagcacttt
    15901 gtaaatctgt tgatgaagca atctctttgt catctacttt tgtaattaca tcgtattttt
    15961 caaggtgacc attggcaggc atattacttt gtaccgaacg aacaactaca ccagatgtaa
    16021 cattacttgg aatattgagt cttctgatgt cgcttgtact cacattagat aaattaacca
    16081 tctggattcc caaagctgga cgagtcactt ttccgttttt ttctaactgt tcaataatat
    16141 tgatagcatc atttgcagga attgcgaaac caagaccttc tacagatgtt cctccatttg
    16201 tagcaatttt acttgaggta attccgataa cctgcccttg aatattgatc agtgggccgc
    16261 cagagttacc tgggttaata gcagtatcag tttggatggc ttttgtagaa atagcttgtc
    16321 catcttccga tcttaaggat acatttctat tgagactgga tacgatacct tgagtgacag
    16381 tatttgcata ttcagaacct aacgggctac cgatggcaat agcagtttct cctacagtta
    16441 acttactaga atcaccaaac tcagctactg ttgtcacttt ttctgaagag attttgacga
    16501 cagcaatatc agagaaagtg tcagctccga caatttctcc aggtacttta gtcccatctg
    16561 acaatcgaat atctactttg ctggcgccat ttataacgtg attgttggtg acgatgtaag
    16621 cttctttatc attcttttta taaataactc cagatccttc actagagatt cgctgagaat
    16681 ctgtgtcagt atcatcattg ccaaatacgc tattttgtct gtttgccgaa taagtaataa
    16741 cagaaacaac agcatctttt actttgttaa cagcctgtgt tgttgaattt tcgttcttat
    16801 aggcagtttg tgtaatagta ctattgttgt tagagttgtt tacactactt ttttgagtta
    16861 gttgagttat tgaaaaacta cccaaggctc cactaaaaaa gctaatgacg ataacgacta
    16921 ataattgaaa ccattttttg taaaatgttt ttagatgttt catatttgcc tccatatgtt
    16981 tgaattactg aaagtataaa ctgactagct taattataac ttaaacacaa aagttttaca
    17041 caaactgtgg ataactcttt tgaaactgtg attttcttaa ttgaaatcta ttttttattt
    17101 tgtgaataag atgtgaaaaa atagagaata tgttagaata gagtcatgaa aattaaagtt
    17161 gtaacagttg ggaaactgaa agaaaagtat ttaaaagatg gtatcgcaga gtattcaaaa
    17221 cgaatttcta gatttgctaa gtttgaaatg attgagttat cagatgaaaa aacaccagat
    17281 aaggccagtg aatcagaaaa tcaaaagatt ttagaaatag aaggtcagag aattttatca
    17341 aaaattgctg accgtgattt cgttattgtg ttagccattg aagggaaaac tttcttctca
    17401 gaagaattta gtaagcagtt agaagaaact tctataaaag gattttctac tcttactttt
    17461 attattgggg gaagtttagg attgtcatca tctgtaaaaa atagagccaa tctttctgtc
    17521 agttttggtc gcctaacctt acctcatcag ttaatgagac tagttcttgt tgaacaaatc
    17581 tatcgcgctt ttacgattca gcagggattc ccctaccata aatagaaaat tgacttttaa
    17641 ttgaattttt ggtagaataa ttgtgttagg tctcatagct cagctggata gagcattcgc
    17701 cttctaagcg aacggtcgca ggttcgaatc ctgctgggat caatataata gcaaagctgg
    17761 gaattttccc ggcttttttc ttaaaaaagt acactttggg agaaaaaaat gacagttgag
    17821 agaattttat ctaaaacgaa attccatttt gtataatggt ttttgtaagt tagcttacaa
    17881 gaaaaaaaca ttttaggaga ttttattatg aaaaacacag ttaaattgga acagtttgta
    17941 gctttgaagg aaaaagactt acaaaagatt aaaggtgggg agatgaggct gtcaaaattc
    18001 ttccgtgatt ttattttaca aagaaaaaag taatgaaata aggggaaaga gtaatggatt
    18061 tatttggatt tgggacagtt attgttcatc ttttaattat tagtcacaac taccatttaa
    18121 tttgtaaagg tcaaataaat agaaaagaat tattcgtttt tggtgcttat acattactaa
    18181 cagaaatagt atttgatttt cccttatata ttctatattt agatgggtta gggattgcaa
    18241 tatttttatt tcctttgggc ttatattcct attttcgatg gatgaaacag tatgagaggg
    18301 atagaggact attcctaagt ttactactat ctcttttata tgagagcact cataactttc
    18361 tgtccgtaac tttctcctct ataacaggag ataattttgt tttacaatat catttcccat
    18421 tctttttcgt tgtgacggtg ttaacctatt ttgttacatt aaaaatcatt tattatttcc
    18481 atttggaact agcctatttt gacaaggact acctttatcc tttcttgaaa aaagtatttt
    18541 ttgctttact attgctacat attgtatctt tcgtttcaga tatggtaagt acgattaaac
    18601 atttgaatag ttttggaagt attttgtcat ctattgtctt tatctctctc cttttgacct
    18661 tctttgcaat gaattctcat aaagttcaaa tggagaaaga gattgctttg aagcagaaga
    18721 aatttgaaca gaaacattta cagaattaca cagatgaaat tgtcggtctg tataatgaaa
    18781 tccgtggttt tcgacatgat tatgctggga tgcttgtcag catgcagatg gcaattgaca
    18841 gtggtaattt acaggaaatt gacagaattt acaatgaagt tttagtcaaa gcaaatcata
    18901 aattgcgttc agataagtac acttactttg atttgaacaa catagaagac tcagctttac
    18961 gaagtttggt tgctcagtca attgtctatg ctcgaaataa tggtgtagag tttacactgg
    19021 aagtaaaaga tacgattacc aagcttccaa ttgaactatt ggatttggtt cgtatcatga
    19081 gcgttttatt gaataatgct gtcgaaggat cggctgatag ctataaaaag cagatggaag
    19141 tagcagttat taagatggaa actgaaacag ttattgtgat tcagaattca tgtaaaatga
    19201 cgatgactcc ttcaggagat ctattttcct taggattctc cactaaggga agaaatcgcg
    19261 gagtcggatt aaataatgtg aaagaactac tagataagta caacaatatt attttagaaa
    19321 cagagatgga aggcagtaca tttagacaaa tcattagatt taagagggaa tttgaatgaa
    19381 agttttaatt ttagaagatg ttattgaaca tcaagtgaga ctagagagaa tattggatga
    19441 aatttcgaaa gaatcgaata ttccaatatc atacaagaca acgggaaaag tccgtgaatt
    19501 tgaagaatac attgaaaatg atgaagtaaa tcagctttat ttcctagata tcgatattca
    19561 tggaattgag aaaaagggat ttgaagtggc tcagttcatt cgtcattaca atccttacgc
    19621 tattatcgtc tttatcacta gtcgatcaga gtttgcgact ctaacctata aataccaggt
    19681 atcagcccta gattttgttg ataaggatat caatgatgag atgtttaaga agagaattga
    19741 gcaaaatatc ttctacacga agagtatgtt acttgaaaat gaagatgttg tagattattt
    19801 cgactacaat tacaagggaa atgatttaaa aattccttac catgatattt tgtatattga
    19861 aacaacaggg gtatctcata aattgcgcat tattggtaag aattttgcaa aagagtttta
    19921 tggtaccatg acagatattc aggaaaagga caaacatact cagcgatttt attctcctca
    19981 caagtcattt ttggtaaata taggcaatat cagagaaatt gatcgaaaaa acttagaaat
    20041 tgttttctat gaagaccatc gttgtcctat ttcaagatta aaaattagaa aattaaaaga
    20101 tattttagag aaaaaatctc aaaagtgatt gacaattagc aagaaattga tataatggtt
    20161 atatctgcta cagatagaag gtccgttggt caaggggtta agacaccgcc ttttcacggc
    20221 ggtaacacgg gttcgaatcc cgtacggact attttatccg ccatagctca gttggtagta
    20281 gcgcatgact gttaatcatg atgtcgtagg ttcgagtcct actggcggag tatagataaa
    20341 agggaacaca gctgtgttcc tctttttgta tcaatttgta tcaccaagca ttttcataag
    20401 gaagtctgtt atttcttgag aactttcttt ttttccatgt gcaatccaag tttggcagac
    20461 accaaaaagt gcatgagtta gatagatgct actatattct aattcagtgg tatttagatt
    20521 cagttgcata aatcgctttt gtaaatctgt actgagcatg atatgaagtt tatttcgtaa
    20581 gaaattttgg atttctttag tcccattttc agaaagaagg gcagccagaa gtggttctga
    20641 ctctagatat tcaaaaactt ctaaaatagc gtctcttttg tgatgagcat gtttttgaaa
    20701 aatatattca aatgtatgga atagcttgct ttgatagtgc tcaatcatat catacttatc
    20761 cttatagtga gtatagaagc tggaacgact aattccggct ttttctacta atttgacagt
    20821 agaaatttta tcaaatggct gttccatcag taattgtacc atagcgtttt caatagttcg
    20881 ctttgttttt aagcgtttgt tactttcttg catatttcct ccttgtaaac aaattagact
    20941 atatgtctaa aaatagattt tttatcttgt aatttagatt ttttaatgta taatctatta
    21001 tatcaaaatt ttagacaata tgtttaaaaa aggagaaact atgtttaaag aatggaaagc
    21061 aatttaaaaa aaaacaacct ttattattgt catgatcggg atttctctta ttccagctct
    21121 gtacaatatc atatttttgt catcaatgtg ggagccatat gggcaattgt ctgacttacc
    21181 tgtggcagtt gtaaataatg ataaagaggc ttcctataat ggtaatacta tggcaatagg
    21241 aaaagacatg gtgtccaatt taaaagaaaa taaaaccttg gattttcatt ttgtagatga
    21301 agaggaagga aagaagggat tggaagatgg cgattactat atggtagtga ctttaccaag
    21361 tgatttatct gaaaaaacaa ctacattatc caatattcaa tcgacagcag cttatcaatc
    21421 attgacaagt gagcaacaaa ctgagataag tgattctgta tctcaaaatt caactgatag
    21481 tattcaatcg gctcagtcaa ttgtagcttt agtacaaggt ttacagggaa gtttagaaaa
    21541 cttacaaaat caatcttcta atctttcgac tttaaaaaat caagctaatc aagtattacc
    21601 tattacttct acttctttga taggattgtc aagtggatta acagagatac aaggagatgt
    21661 tactagcaaa ttagttcctg ccagtcagtc gattgcatca ggtgtaaacg catatactac
    21721 aggtgttgat aaagtttctc agggcgcaag tcaactaagt gaaaaaaatg ccaccttgac
    21781 aggtagtttg gataaactag tttcaggctc aaacaccttg acacaaaaat cttctagatt
    21841 gacagcagga gttggttaat tacaatcagg atctgggcaa ttagcagaca aatccagtca
    21901 gttactttca ggtgcttctc cattagagaa tagagctaat aaattggcag atggatctag
    21961 gaaactagca gaaggtggaa caaagttaac ttctggattg gaagatttac agacaggact
    22021 tgcttcttta ggacaaggac taggtaatgc tagtgatcaa ctcaaatcag tatcaacaga
    22081 atctaaaaat gcagagattt tgtcaaatcc actcaatctt tcaaaaacag acaatgatca
    22141 agttcctgta aatggaatcg caatagctcc ttatatgata tcagttgctc ttttttttgc
    22201 agcaatatca acaaatatga tatttgcgaa attgccttca ggacgtcatc cagagagccg
    22261 ttgggcttgg ttgaaatctt gagctgaaat aaatggtatt atagctgttt tggcaggaat
    22321 tttggtatat ggaggagttc agcttattgg tttaactgct aatcatgaga tgagaatatt
    22381 tattctcatc atcctaacaa gtttagtatt catgtctatg gtgaccactt tagcaacgtg
    22441 gaatagccgt ataggagctt ttttctcact tattttgctt ttactacagt tagcatcaag
    22501 tgcaggtact tatccacttg ctttgacaaa tgatttcttt agatctatta atccctggtt
    22561 accaatgagc tattcagttt cgggattacg acaaacaatc tctatcaaca agtcattttc
    22621 ctagctgtca tactagctct atttactggt ttaggtatgc tagcctatca acataagaaa
    22681 atggaagaag attaaaaaaa tcgaccgatt aactggtcga ttttttatgc cttagatgac
    22741 tttcgtctgt gattatagat tccaaatagt aagagagaag taaaggaaca gattgctcca
    22801 gtaataaaac cattgggaat gaaggaaagt gtaatagttc ctttcccctt gggaatgtca
    22861 actttcataa atccagtttg agcttgttta atttctattt tcttaccatc ttggtaggca
    22921 gaccaacctt tgtcataagg aatggtgaag aaaatagatg tatcttgttg gacatcatat
    22981 gtagcaaaaa ccttgttttt agaagttgat actgtgacag gttgttcttt aattttttga
    23041 attgcctcgg tgaaagtttt ggtatctaaa cgatagaagg taggagattc aaatgatact
    23101 tgtgaatttc cagggaaact aacattgata ttgaaagttt ttttctcttt agtatatcct
    23161 agattaaaga aggagaagac attatcagtt gtaaaagtct ttttttcacc atttacaagg
    23221 atgtcaacct tcttttgttt atcgttagaa aagtgaaggt ttatgaaaga gagataaact
    23281 tggctgtttt ctggaacttc aatttgatac tggattgctg catcttcatt tgaagaactt
    23341 gtgacactaa tcaaatcatt agtattttct attttttctg ttttttcata aggtattgga
    23401 gaaaaataat caaaattgac gttagcaagt tgatttaaaa atgaggcctg attatccaag
    23461 gtatgttcat tgaacttgac atcattgtaa acagattgac tagcaactgc aatcggaaga
    23521 gagtattgat tttcatatag ggtaagatta tctttttgat agatatcttt aaagccatac
    23581 ttatcaatag gactgtctga gatattgtac tggataccaa ataaactatc agccaaaata
    23641 ctattatttg catatcggag attgagatta gtcccagagg atttaaaacc aagtttatct
    23701 aaagtagagc ttgatgaacg atttcgaaca gatgaaaatt gagagattcc attgtagttg
    23761 aatttcatac tgtcatttcc tgtctgagtt tgtagttttt cagtacgagt aaattgattt
    23821 ccaatatatg ttgagaaaga ttccatagct gggatatctc gactataagc acttcgagaa
    23881 gcaaatcccc attccttagc aattccgtcc atttgagatg aagcatttaa actcatttca
    23941 accagtataa ataaagagat tagaatggca aatagattca cagatataaa ctttttgata
    24001 actgcaagga gtaaaagaga atagacaacc aaaaattcaa gagtaagcag aatattcaaa
    24061 tctgttaaaa aagaataatg cgattttaga tagatggtag ctaaaaatcc tgctactaca
    24121 agaaaaagcg aaactaaaaa attccagact ttaagttctt tcagacgatt taagacttct
    24181 gctgctgtgt aaattaacaa ggtagagaaa atccaagcat agcgatgtaa aaacatgttt
    24241 ggagtatgca tgccttgcca aaataagtca agagcttcta tgtaaaagct tgcaattaga
    24301 aatgcaaaga atattacata tatgagtttc acgtgaaact taatagattt cagcgtaaaa
    24361 aataaaatgg tcaaaataaa gggaagtagt ccaacaaaaa tcattgggat ggccccatac
    24421 tttgttgtgt caaaggaacc aatgaattgc ttagcaaaga gatcaagata ccagctactt
    24481 tcagtttgaa actttgtaac ttcagtcaat ttttccccat gtgtctgtaa atcaaacaga
    24541 gtgggaagag tcataatcaa actagccata ccagctaaaa aggagataac tatgaaatca
    24601 agaacagatg attttcgagt cttaaagtcc cacgaaattt gacagagata ccagaaaata
    24661 agaaacaata ctgtcatata tccaaaataa taattttgaa taaataagat tgacagactt
    24721 gtaaagtaca ataggagttt cttttcagtt atcagtagat gtaaaccagt tataattaaa
    24781 ggaatcaaga taaaaacatc tagccaggtt tttatctcta attgactgac agtgaaactc
    24841 atcagagcat aggaagtaga taaggctagt tttaaaatct gagggataga ttgaaacaat
    24901 ttattcaaac taaaaaaggt tgacagacca atcaatccaa attttaagag agttgtcaga
    24961 tagatagcat ctggcatatt cgttagatca aaaaagtaaa ccagaggcgc gagaaaacta
    25021 cccaagtaat aactagatag ggcatagaag tttagcccta gaccacttgt aaaggtgtaa
    25081 aacagattac tatttccatg taggatattt cgtaaggcta catcaaaaat aacgtattga
    25141 tgaaagccat ctcctaatag aggagagttg tcgctattcc agtagatacc ttgagataga
    25201 tatactccag acataatcac tacaggaatg atgaaagaaa taaaataggt tcgatatgtt
    25261 tttaaaaatg atttcatgtt acctcgtaga atgatagaaa actcagttgg ttaacccaac
    25321 tgagttttga agttttattt agtctttcca aagttcttta acttttgctt gtacttctgc
    25381 attttctagg aattcatcgt aggtttcatc gatacggtca atgacgccat ttttagataa
    25441 gacaatgata tggttagcca aagtttgaat aaattcgtgg tcatggctgg caaagatgat
    25501 tgattcttta aagtttttca atccatcatt caagcttgag atagattcca agtccaagtg
    25561 atttgttgga tcatcaagta caaggacatt tgattttaag agcatgagtt ttgaaagcat
    25621 gacacgaact ttttctcccc ctgacaagac atttacaggt ttgttaactt catctccaga
    25681 gaagagcata cggccgagga agccacgtag gaaagtattg tcatcttctt ctttacttgc
    25741 gaattgacgc aaccagtcaa gaattgattc tcctcctgca aaatcagctg agttatcttt
    25801 tggtaggtaa gattgactag ttgtaactcc ccacttgaca gttccttcat agtcaatatc
    25861 tcccatgatt gcacgaatta atgcagtcgt ttgaatatca ttttgtccaa taagtgctgt
    25921 cttatcatct ggacgcaaga tgaaactaat attatccaag atagtttcac catcaatctt
    25981 tacagttaaa ttttctactg tcaagagatc attaccaatc tcacgttccg ctttaaagtt
    26041 gataaatgga tatttacgac tagatggcac aatctcttct agctcaatct tatcaagcat
    26101 tttcttacgt gatgttgcct gccttgactt agaagcattg gcagagaaac gagcaacaaa
    26161 ttcttgcaat tgtttaattt tttcttctgc tttagcatta cggtctgcta gcaatttagc
    26221 agcaagctca gaagattcct tccagaagtc gtagtttccg acatagagtt tgatttttcc
    26281 aaagtcaagg tcggccatgt gagtacaaac tttgtttaag aagtgacggt cgtgggatac
    26341 tacgataact gtgttatcaa agtcaatcaa gaagtcttct aaccaagtaa tcgattggat
    26401 atccaaaccg ttagtaggct cgtccaagag aagaacatct ggtttaccaa aaagtgcttt
    26461 ggcgaggaga acctttactt tttcaccgtt ggccaattcg ctcatgtttt ggtagtgtaa
    26521 ttcttctgga atgtttaggt tttgaagtag ttgagaggct tcactctctg cttcccaacc
    26581 tccaagttcg gcaaactctc cttcgagttc ggcagcacga accccgtcct cgtctgagaa
    26641 atcttccttc atgtagatag catctttctc tttcatgatg ctataaagtt tttcatttcc
    26701 catgataacg acatcaatgg cacgttcatc ttcgtagtca aagtgatttt gacgaagaac
    26761 agagagacgt tcatctggac caagagagat gtgaccagta gtaggttcga tatctccagc
    26821 taaaattttt aaaaaggttg attttccggc accattagca ccgattaatc cgtaagtatt
    26881 tccttctgta aatttgatat tgacatcatc aaaaagtttg cgatcactaa aacgtagtga
    26941 aacatcagat actgtaagca atgtttttct cctatatgtg taatatattt attctactag
    27001 aaaatacaga aatattcaaa tttttatttg tcaattttgt gtaaattata tttacagtat
    27061 cctttacaca aatctgtaaa aagcaaggct gatttatttt gataaattac ggttatttca
    27121 ttaaaaaaat gctataattg aaaggactat atcgaaggag aacaaaatga ctaaacccat
    27181 tattttaaca ggagaccgtc caacaggaaa attgcatatt ggacattatg ttggaagtct
    27241 caaaaatcga gtattattac aggaagagga taagtatgat atgtttgtgt tcttggctga
    27301 ccaacaagcc ttgacagatc atgccaaaga tcctcaaacc attgtagagt ctatcggaaa
    27361 tgtggctttg gattatcttg cagttggatt ggatccaaat aagtcaacta tttttattca
    27421 aagccagatt ccagagttgg ctgagttgtc tatgtattat atgaatctag tttcgttagc
    27481 acgtttggag cgaaatccaa cagtcaagac agagatttct cagaaaggat ttggagaaag
    27541 cattccgaca ggattcttgg tctatccaat cgctcaagca gctgatatca cagctttcaa
    27601 ggctaattat gttcctgttg ggacagatca gaaaccaatg attgagcaaa ctcgtgaaat
    27661 tgttcgttct tttaacaatg catataactg tgatgtcttg gtagagccgg aaggtattta
    27721 tccagaaaat gagagagcag ggcgtttgcc tggtttagat ggaaatgcta aaatgtctaa
    27781 atcactaaat aatggtattt atttagctga tgatgcggat actttgcgta aaaaagtaat
    27841 gagtatgtat acagatccag atcatatccg cgttgaggat ccaggtaaga ttgagggaaa
    27901 tatggttttc cattatctag atgtttttgg tcgtccagaa gatgctcaag aaattgctga
    27961 tatgaaagaa cgttatcaac gaggtggtct tggtgatgtg aagaccaagc gttatctact
    28021 tgaaatatta gaacgtgaac tgggtcctat tcgtgagcgc cgtattgaat ttgctaagga
    28081 tatgggagaa gtttataata tgattcaaaa aggtagtgaa agagcgcgtg aagttgcggg
    28141 tcaaacccta tctgaggtaa aaggggcaat gggacttcat tactttaact aagtttattt
    28201 tacaagaaac tatcttttct atctcgaaga aaagatagtt ttttatttac ccctgtaaca
    28261 tttgacaaat ttttatagaa tggtatgata gatacaatat aaaaagagtc aagctcaaaa
    28321 agaaagaaaa gaggaaactt cgaatgtcta attgggacac taaatttttg aaaaaaggtt
    28381 ttacctttga tgatgtattg cttattccag ctgaaagtca tgtgttgcct aacgatgcag
    28441 atttaacaac taaattggca gataatttga ctttaaatat cccaattatt accgctgcca
    28501 tggacacagt tacagagagt caaatggcca ttgctattgc tcgtgcaggc ggtctcggag
    28561 ttatccataa aaacatgtca attgctcaac aagcagacga ggttcgtaag gtaaaacgtt
    28621 ctgaaaatgg agttattatt gatccgttct tcttgacgcc tgaacataca attgctgaag
    28681 cagatgagct tatgggtcgt taccgcatca gtggtgttcc agttgttgaa acacttgaaa
    28741 atcgtaaatt ggttggtatt ttgacaaacc gagatcttcg ttttatttca gattataatc
    28801 aaccaatttc aaaccatatg actagtgaaa atcttgttac tgctcctgtg ggtacggatc
    28861 ttgcaacggc tgagagtatt cttcaagagc atcgtattga aaaacttccg ttggtcgatg
    28921 aagaaggcag tctttctggt ttgatcacta tcaaagatat tgaaaaagtt attgagtttc
    28981 caaatgcagc taaagatgag tttggtcgtc ttctagttgc aggtgcagta ggtgttactt
    29041 cagatacatt tgaacgtgca gaggctcttt ttgaggcagg agcggatgcg attgttattg
    29101 atactgcaca tggtcattct gcaggtgtct tgcgtaaaat tgccgagatt cgtgctcatt
    29161 tcccagatcg gactttgatt gctggaaata ttgctactgc tgaaggtgca cgtgcccttt
    29221 atgaagcggg tgtagacgtt gttaaggttg gtattggacc aggttctatc tgtactactc
    29281 gtgtgattgc tggtgttggt gttccgcaag taacagctat ctacgatgct gcagctgttg
    29341 cgcgcgaata tggtaaaacg attattgctg acggtgggat caagtattct ggagatattg
    29401 taaaagcact tgctgcaggt ggaaatgctg ttatgcttgg atctatgttt gctggaactg
    29461 atgaagctcc aggcgaaact gaaatcttcc aaggacgtaa attcaagact taccgtggta
    29521 tgggatcaat tgctgctatg aagaaaggtt caagcgaccg ttatttccaa ggttctgtca
    29581 atgaagcaaa caagcttgtt ccagaaggaa ttgaaggtcg tgttgcttat aaaggagcgg
    29641 cagctgatat tgttttccaa atgattggtg gtattcgctc tggtatgggt tactgtggtg
    29701 cagctaacct taaagaacta cacgataatg ctcaatttat tgaaatgtct ggtgctggtt
    29761 tgaaagaaag ccatcctcat gatgtgcaaa ttactaatga ggcaccaaat tattctatgt
    29821 aaaaaacaat gaaaagaact ccagtgaaaa caggagttct tttacaatgt tgtcaatttc
    29881 catttacagc agctttacca tcctgaatag tgaagatact tagattttct ggcagatttt
    29941 gaagatggtc taagcttgtt gttgtgataa aggtttggat tgattgagaa atcgtttcta
    30001 ataattttaa ctgtctagtg ttgtcaagtt cactcatcac atcgtcaagc agtaatatag
    30061 gagattctgt ggtaatgctt tccattaatt cgatttctgc taattttatc gagaggacga
    30121 gactacgatg ttgaccttgg cttccgaaac tagcatccat cccatttata taaaaagaaa
    30181 tgtcatctcg atgaggaccg acaccagtat tctttttaaa taaatctctg gatctacttt
    30241 tttctaaagc aattttgaaa gattcggata agttttgttt gtcagttata ttgacagaag
    30301 attgatagga tattgacaac tcttcgatct gattagagag ttcaaaatgt ttcttacgcc
    30361 caaatgattc tagttttttt atgaaatcta agcggtgatt cattacacga catccataat
    30421 caactagctg atcatctaac acagaaagga atgtttcatc tattttttga gctgatttta
    30481 ggtaagtgtt tctttgcttt aggatgtggt tataattggt taagtcagat aaatagattg
    30541 gcttaatttg cccaagttcc atatcaatga attttcgtcg aatcgaaggt gctcctttaa
    30601 ttagttgtaa atcttcagga gcaaataaga caacattcat gtgtcctaca taatctgaaa
    30661 ggcgtgcctg ttttaagtga ttaacttttg ttacacgacc tttttgtgtt agttcgattt
    30721 ctaggggaat ggatccagtt tttttctgaa cgagacctga aagatgaagt tgttcctcat
    30781 caaaatgaat gagattttta tctgttcgag ttcgatgact acgcgttaag gctaaaaaat
    30841 agatagcctc taacatgttt gtttttcctt gtgcattacg tcccaaaaag acattcaatt
    30901 taggattaaa gtctattttc gtttctttgt aattacgaaa agtcttgaga gatagatgtt
    30961 gtagccacat gattatctac cagggaatcg tggagcttgt tggcttttag gtgatgaagc
    31021 aggtttcgat ttgtcttttt taactccctt attcatcttt ttgacaagtt tagcgatccg
    31081 ttctttttca actttatcag cttggtattc atcttgttct tcagaagtag gttgtgtcaa
    31141 caagatgtca atgttcatgt cagggatgtc aactttatcg ccaatacgaa gtttttttcc
    31201 acgacggctc tctaattccc tattaaagta aacagaatgt tcagagagaa atgatttaat
    31261 agctcctccg ctatgtgtaa ttccaagttc tttgagtagt gcttggaggg taataaattc
    31321 ttcaaataat ttgtattcca taattcacct caatctttgg tattatacca tattttccta
    31381 aaaatagtga gagagacagc gagaaatgta agcgattttt atttcaaaag tgttacaggg
    31441 aacaagaaaa tttcaggttt tcgtgatata atagaagtct gtatataagg aggtaaatca
    31501 tggagttagt gcatggaatt tcaacacatt ttatccaatc aaaaaagttt aaaacaaaca
    31561 aaattaccgt gcgttttacc gctccattat cccttgatac gattgcaggt cacatgttga
    31621 gtgcaagtat gctagagact gctaatcaga tgtaccccac ttctcaagat ttgaggagac
    31681 acttggccag tctatacggt acagatatgt caaccaattg tttcagaaga gggcaaagcc
    31741 acattataga attgacattt acctatgttc gtgatgagtt tttaagtagg aaaaacgtgc
    31801 taacctctca gattttggaa cttgtaaaag aaactctttt ttcacccgta gtagttgata
    31861 atgggtttga tccggcctta tttgaaattg agaaaaaaca attgctagca agtttagcag
    31921 ctgatatgga tgattctttt tattttgcac ataaagaatt ggataaattg ttttttcatg
    31981 atgaacgtct tcaattggaa tatagtgatt tacgaaatcg tattttagct gaaactccac
    32041 aaagttctta ttcttgtttc caagaatttt tagccaatga tcgaatagat ttctttttcc
    32101 taggtgattt taatgaggtt gaaattcaaa atgtattaga atcatttggc tttaaaggtc
    32161 gaaaaggaga tgtgaaggtt cagtattgtc aaccttattc taatatcctt caggaaggta
    32221 tggttcggaa aaatgtggga caatccattt tggaattagg ttatcattac cgttctaaat
    32281 atggtgatga acaacattta cccatgattg taatgaatgg tttacttggt ggatttgctc
    32341 actctaagct ctttacaaat gtccgtgaaa atgctggatt agcttatacc atttcaagtg
    32401 agcttgattt atttagtgga ttcttgagga tgtatgctgg tatcaatcga gaaaatcgta
    32461 accaggctcg taaaatgatg aataatcaac tgcttgattt aaaaaaaggt tattttacag
    32521 agtttgagtt aaatcagacc aaggaaatga ttcgttggtc gttgttactt tctcaagata
    32581 atcaatcttc attgattgaa cgtgcttatc aaaatgcctt atttggaaaa tcttcagcag
    32641 actttaaaag ttggattgca aagcttgaac aaattgacaa agatgctatt tgtagagtag
    32701 ctaataatgt gaaactacaa gcgatttact ttatggaagg aatagaatga caaaggttgt
    32761 ttttgaagaa aaatactatc cagctgtaaa agaaatggtt tatcgaactc gtttggccaa
    32821 cggattgaca gttgctcttt tgcctaaaaa ggaatttaaa gaggtttacg ggagtgtcac
    32881 tgtacagttt ggttcggtag atacgtttgt cacagaagtt gacggagatg taaaacaata
    32941 tcctggagga attgctcatt ttcttgaaca taaattattt gagagagaag attctagtga
    33001 tttgatgtcg gcttttacga gtctaggtgc agatagtaat gcctttacaa gctttacaaa
    33061 aacaaactat cttttttcag caacggatta ttttttagaa aatttagatt tacttgatga
    33121 attggtaaca tcagcacact ttactgaagc ttccattctg acagagcagg atattattca
    33181 gcaagaacga gaaatgtacc aagatgatcc agattcgtgt ttattctttt caactttagc
    33241 gaatttgtat cctggtacac ctttagcaac tgatatagtt ggaagtgagg agtccatttc
    33301 ccaaatcaat ctaactaatt tgcaagaaaa ttttacaaag ttttacaaac ctgtaaacat
    33361 gtctctgttt ttagttggta attttgatgt ggagcgagta caggactatt ttgaaagcaa
    33421 agaactgaaa gattcagatt ttcaggaagt agcaagagaa aagttgtttt tacagcctgt
    33481 aaagccaaca gatagtatga gaatggaagt atcttctccc aaactagcga ttggagttag
    33541 aggtaagcga gaagtttctg aagcggattg ctatcgacat catattttat taaaattatt
    33601 gtttgcaatg atgtttggtt ggacttcgga tcgttttcaa aaatgttatg aatcaggtaa
    33661 aattgatgcg tccttatctc tggaagttga aataacaagt cgctttcatt ttgtcatgtt
    33721 gacaatggat acgaaagagc cagttgcttt gtctcatcaa tttaggaagg ctattcgtaa
    33781 ttttacaaag gatttagata ttacagagga acatttagat attatcaaaa gagagatgtt
    33841 tggcgaattt ttcagtagca tgaactctct tgaatttatt gcaacgcaat atgatgcttt
    33901 tgaaaatggt gagacaattt ttgatttgcc gaaaatttta caggaaatta ctttagagga
    33961 tgtccttgat gctggacatc atttaataga tgatggtgac atagttgatt ttacaatatt
    34021 cccatcgtag taacctatta taatagacac tagaaagaag ggatgacaag tatgagaaaa
    34081 aaaacaattg gagaggtttt acgattagct agaatcaatc agggattgag tttagatgaa
    34141 ttgcagaaaa agacagaaat ccagttagat atgttggaag caatggaagc agacgatttc
    34201 gatcaacttc caagtccttt ttacacgcgt tctttcttga aaaaatatgc atgggctgtt
    34261 gagttagatg accaaattgt tttggatgct tatgattctg ggagtatgat tacttatgag
    34321 gaagtagatg ttgatgaaga tgagttgaca ggtcgtagac gttcaagtaa gaaaaagaag
    34381 aaaaaaatat catttttacc tttattttat tttatccttt ttgctttatc gattttaatt
    34441 tttgtgactt attatgtttg gaactatatt caaactcaac cagaggagcc ttctctttct
    34501 aattacagtg tggttcaatc aacaagttca actagctctg ttccccactc ctcaagtagt
    34561 agttcttcta gtatagaatc agctataagt gtatcaggcg aaggaaatca tgtagaaatc
    34621 gcttataaga caagtaagga aacagttaaa ttgcaattgg cagtttcaga tgttacaagt
    34681 tgggtcagtg tttcagaaag cgaacttgag ggcggtgtaa ccttatcgcc aaagaagaaa
    34741 agtgcagaag caacagttgc aactaaaagt cctgtaacaa ttacgttagg tgttgtaaaa
    34801 ggtgttgatt tgacagtaga taatcagact gttgatttat cgaaattaac agctcagact
    34861 ggacaaatca ctgtaacctt tactaaaaat taaggaaaaa cgaatgaaaa aagaacaaat
    34921 tcccaatctc ttaacaatag gtcgaattct ctttatacct atttttatct ttattttaac
    34981 gataggaaat tcgatagaga gtcatatagt tgcagctatt atctttgctg ttgccagtat
    35041 taccgactat ttagatggat atttagctcg taaatggaat gtggtcagta attttggtaa
    35101 atttgcagat cctatggcgg ataagttact agttatgtcg gcttttatta tgttgattga
    35161 gttaggtatg gctccggctt ggattgttgc agtgattatc tgtcgtgagt tagctgtgac
    35221 aggtttaagg cttttattgg ttgaaactgg tggaacaatt ttagcagcag caatgcctgg
    35281 aaaaattaaa acttttagtc agatgtttgc cattattttc ttgctattac attggacttt
    35341 gcttggtcaa gttctacttt atgtagcctt atttttcact atctactctg gctatgacta
    35401 tttcaagggt agtgcctatg tatttaaagg gacatttggt tcgaaatgaa atcaataatt
    35461 gatgtaaaaa atctttcttt tcgctataaa gaaaatcaga actactacga tgtgaaggat
    35521 attacgtttc acgtgaaacg tggagaatgg ctttcgattg tagggcataa tggtagtggt
    35581 aaatcaacga cggttcgatt aattgatggc ttactggaag cagaatccgg agagattgta
    35641 attgatggcc aacgtttgac tgaggaaaat gtttggaata tacgtcgtca aatcggtatg
    35701 gtttttcaaa atccagacaa tcaatttgtt ggagcgactg ttgaagatga tgttgctttt
    35761 ggtttggaaa atcagggact ttctcgtcaa gaaatgaaaa agagagtgga agaagctctg
    35821 gctttagttg gcatgttgga ctttaaaaag agagagccag cgcgtctatc aggtggccaa
    35881 aagcaacgtg tggccattgc aggtgttgta gccctaagac cagctatttt aatcttagat
    35941 gaagcaacga gtatgttgga tcctgagggg cgtagagaac ttattgggac agtaaaagga
    36001 attcgaaaag actatgatat gacggtcatt tctattaccc atgatttgga agaagtcgcc
    36061 atgagtgatc gcgtattggt catgaaaaaa ggggaaattg aatcaactag tagtccaagg
    36121 gagcttttct ctcgaaatga tttagatcaa attggattag acgatccttt tgctaatcaa
    36181 ttaaaaaaat ctttgagcca gaatggctat gatttacctg aaaattattt gacagaaagt
    36241 gagctagagg ataagctatg ggaattgctc tagaaaatgt gaattttaca tatcaagaag
    36301 gtactccctt agcttcagca gctttgtcgg atgtttcttt gacgattgaa gatggctctt
    36361 atacagcttt aattgggcac acaggtagtg gtaaatcaac tattttacaa ctcttaaatg
    36421 gtttattggt gccaagtcaa gggagtgtga gggtttttga taccttaatc acctcgactt
    36481 ctaaaaataa agatattcgt caaattagaa aacaggttgg cttggtattt cagtttgctg
    36541 aaaatcagat ttttgaagaa acggttttga aggacgttgc ttttggaccg caaaattttg
    36601 gagtttctga agaagatgct gtgaagactg cgcgtgagaa actggctctg gttggaattg
    36661 atgaatcact ttttgatcgt agtccgtttg agctgtcagg gggacaaatg agacgtgttg
    36721 ccattgcagg catacttgcc atggagccag ctatattagt cttagatgag ccaacagctg
    36781 gtctagatcc tctagggaga aaagagttga tgaccctgtt caaaaaactc caccagtcag
    36841 ggatgaccat cgtcttggta acgcatttga tggatgatgt tgctgaatat gcgaatcaag
    36901 tctatgtaat ggaaaaggga cgtttagtaa aggggggcaa accaagtgat gtctttcaag
    36961 acgttgtttt tatggaagaa gttcagttgg gagtacctaa aattacggcc ttttgtaaac
    37021 gattggctga tagaggcgtg tcatttaaac gattaccgat taagatagag gagttcaagg
    37081 agtcgctaaa tggatagtat gattttaggg cgttatatcc caggggattc gattgttcac
    37141 cgattggatc cacgtagcaa attgcttgct atgatgctac tgattttgat tgtgttttgg
    37201 gctaataacc ccttgacgaa tctgattctt tttatagcga cagggatatt tattgccttg
    37261 tcaggagtat ctctttcatt ttttattcag ggcttgaagt ctatgttttt cttgattgcc
    37321 ttcacaacta tttttcaact atttttcatt tctaatggga atgttttatt tgagttttcg
    37381 tttgtgagaa tcacggatta tgctttgcaa caagctggga ttattttttg tcgctttgta
    37441 ttgattattt tcttttcaac tttgttaacc ttaacaacca tgcctttaag tttggcatca
    37501 gctgtcgaag ctttattagc acctttaaag cgtgtgaaag ttccagttca tgaaattgga
    37561 ttgatgctgt ctatgagttt gcgttttgtc ccaaccttga tggatgatac gactcggatt
    37621 atgaatgcac agaaagctcg tggagtggat tttggagaag gaagcatcgt tcaaaaagta
    37681 aaggcgatga ttcccatttt gattcctctt tttgcgacaa gtttaaaacg tgcagattcc
    37741 ttggctatcg ctatggaagc gcgtggctat cagggtggaa aaggcagaag tcaataccga
    37801 caattgaaat ggactctgaa ggatacgctg accattcttg ttattctcgt acttggttgt
    37861 tgtttatttt tcttaaaatc ttagtagctt tcaggaattg ataaaaagtt actgtaacag
    37921 tttttgatat aaaggtagga atatgaaccg ttttaaaaaa tcaaaatatg tcattattgt
    37981 ttttgtcact gttctgcttg tgtcagctct cttagcgacg acttattcaa gtacaattgt
    38041 gacaaaatta ggagatggaa tctcattggt tgatagagtt gtacaaaaac cttttcagtg
    38101 gtttgattct gtcaaatcag atttggctca tttgacacga acatataatg aaaatgaaag
    38161 tttgaagaaa cagctttacc aattagaagt taaatcaaat gaggtggaaa gtttaaagac
    38221 agaaaatgaa caactgcgcc aattgcttga tatgaagtct aaattgcaag ccacaaagac
    38281 tttagcagca gatgttatta tgcgttctcc ggtatcttgg aagcaggagt tgaccttaga
    38341 tgcaggtaga tcaaaaggtg cttctgagaa catgttagct attgcaaatg gtggcttgat
    38401 tgggagtgtt tcaaaagtag aggagaactc tactatagtc aaccttctga caaatacgga
    38461 aaatgctgat aagatttctg ttaaaattca acatggctct actacaattt atggaattat
    38521 tattggctat gacaaggaaa atgacgttct taaaattagc caattaaata gtaatagcga
    38581 tattagtgcg ggagataagg tgactactgg tggattagga aactttaacg ttgctgatat
    38641 tcctgttggt gaagtggttg ccacaacgca tagtacagac tatttgacac gagaagtaac
    38701 tgttaaattg agtgcagata ctcataatgt agatgtgata gaattagtgg ggaattcata
    38761 atgagacagt tgaagcgagt tggagtattt ttattgcttc ctttctttgt tctaattgac
    38821 gcccatatta gccagcttct gggctcattt ttcccccatg tacatttggc tagtcatttt
    38881 ctttttctat ttctcttatt tgagacgata gaagtatcag agtatctcta cctagtctat
    38941 tgttttgtta taggcttggt ttatgatgtt tactttttcc atctaatagg gattacaact
    39001 ctcttattta tcttattggg agccttcctt cataaattga atagtgttat tttgttgaat
    39061 cgttggacaa gaatgctagc tatgattgtg ctgacattcc tgtttgaaat gggtagttat
    39121 cttttggctt ttatggtagg gttgacagta gatagcatgt cgatttttat agtctatagc
    39181 ttggtaccga cgatgatttt aaatttttta tggattactg tttttcaatt tatttttgaa
    39241 aaatattatc tataagaacg acatataaat gtaacaaagg cgtaatattt attaggcctt
    39301 tttttggtat actagtattg tctttaaaag aaggagtatc tacgtaatat gaagaaaaaa
    39361 atcttagcgt cacttttatt aagtacagta atggtttctc aagtagctgt tttaacaact
    39421 gcgcatgcag aaacgactga tgacaaaatt gctgctcaag ataataaaat tagtaactta
    39481 acagcacaac aacaagaagc ccaaaaacaa gttgaccaaa ttcaggagca agtatcagct
    39541 attcaagctg agcagtctaa cttgcaagct gaaaatgata gattacaagc agaatctaag
    39601 aaactcgagg gtgagattac agaactttct aaaaacattg tttctcgtaa ccaatcgttg
    39661 gaaaaacaag ctcgtagtgc tcaaacaaat ggagccgtaa ctagctatat caataccatt
    39721 gtaaactcaa aatcaattac agaagctatt tcacgtgttg ctgcaatgag tgaaatcgta
    39781 tctgcaaaca acaaaatgtt agaacaacaa aaggcagata aaaaagctat ttctgaaaaa
    39841 caagtagcaa ataatgatgc tatcaatact gtaattgcta atcaacaaaa attggctgat
    39901 gatgctcaag cgttgactac gaaacaggca gaactaaaag ctgctgaatt aagtcttgct
    39961 gctgagaaag cgacagctga aggggaaaaa gcaagtctat tagagcaaaa agcagcagct
    40021 gaggcagagg ctcgtgcagc tgcggtagca gaagcagctt ataaagaaaa acgagctagc
    40081 caacaacaat cagtacttgc ttcagcaaac actaacttaa cagctcaagt gcaagcagta
    40141 tctgaatctg cagcagcacc tgtccgtgca aaagttcgtc caacatacag tacaaacgct
    40201 tcaagttatc caattggaga atgtacatgg ggagtaaaaa cattggcacc ttgggctgga
    40261 gactactggg gtaatggagc acagtgggct acaagtgcag cagcagcagg tttccgtaca
    40321 ggttcaacac ctcaagttgg agcaattgca tgttggaatg atggtggata tggtcacgta
    40381 gcggttgtta cagctgttga atcaacaaca cgtatccaag tatcagaatc aaattatgca
    40441 ggtaatcgta caattggaaa tcaccgtgga tggttcaatc caacaacaac ttctgaaggt
    40501 tttgttacat atatttatgc agattaattt acagagggac tcgaatagag ccctcttttc
    40561 aggttttacc gtgacaatcc ctattaaaaa ttatatcaaa atagcttgaa aatattggaa
    40621 aagtatggta aaatgaaaat tgtcgtgtga acgataatac tcattcttga tgaattgtga
    40681 agcagttgcc cttgggtcgt tttgcgagtt gaagtcaaga agaggaaaaa aacaaaaagg
    40741 agaaatactc atggcagtaa tttcaatgaa acaacttctt gaggctggtg tacactttgg
    40801 tcaccaaact cgtcgctgga atcctaagat ggctaagtac atctttactg aacgtaacgg
    40861 aatccacgtt atcgacttgc aacaaactgt aaaatacgct gaccaagcat acgacttcat
    40921 gcgtgatgca gcagctaacg atgcagttgt attgttcgtt ggtactaaga aacaagcagc
    40981 tgatgcagtt gctgaagaag cagtacgttc aggtcaatac ttcatcaacc accgttggtt
    41041 gggtggaact cttacaaact ggggaacaat ccaaaaacgt atcgctcgtt tgaaagaaat
    41101 taaacgtatg gaagaagatg gaactttcga agttcttcct aagaaagaag ttgcacttct
    41161 taacaaacaa cgtgcgcgtc ttgaaaaatt cttgggcggt atcgaagata tgcctcgtat
    41221 cccagatgtg atgtacgtag ttgacccaca taaagagcaa atcgctgtta aagaagctaa
    41281 aaaattggga atcccagttg tagcgatggt tgacaccaat actgatccag atgatatcga
    41341 tgtaatcatc ccagctaacg atgacgctat ccgtgctgtt aaattgatca cagctaaatt
    41401 ggctgacgct attatcgaag gacgtcaagg tgaggatgca gtagcagttg aagcagaatt
    41461 tgcagcttca gaaactcaag cagattcaat tgaagaaatc gttgaagttg tagaaggtga
    41521 caacgcttaa tttatacaaa tagtaattac ctaggagggc ggggcttagc ccggctctcc
    41581 tattttcaaa aaatatagga gaattaaaat ggcagaaatt acagctaaac ttgtaaaaga
    41641 gttgcgtgaa aaatctggtg ccggtgttat ggacgctaaa aaagcgcttg tagaaacaga
    41701 cggtgacatc gaaaaagcga ttgaattgct tcgtgaaaaa ggtatggcta aggcagctaa
    41761 gaaagctgac cgtgttgctg cagaaggttt gactggtgtt tatgttaacg gtaatgttgc
    41821 agcagttatt gaagtaaacg ctgaaactga cttcgttgca aaaaacgctc aattcgttga
    41881 attggtaaat actacagcta aagtcattgc tgaaggaaaa cctgctaaca atgaagaagc
    41941 tcttgctttg ataatgcctt caggtgaaac tcttgaagct gcatacgtat ctgcaacagc
    42001 aactatcgga gagaaaatct cattccgtcg ctttgcattg attgaaaaaa cagacgcaca
    42061 acactttgga gcataccaac ataacggtgg acgtatcggt gttatttcag ttgttgaagg
    42121 tggagacgaa gcacttgcta aacaattgtc aatgcacatc gcagcgatga aaccaacagt
    42181 tctttcttac aaagaattgg atgagcaatt cgttaaagat gagttggcac aattgaatca
    42241 cgttatcgac caagacaacg aaagccgtgc aatggttaat aaaccagctc ttccacactt
    42301 gaagtatgga tcaaaagctc aattaactga tgatgttatt gctcaagctg aagctgacat
    42361 caaagctgaa ttggctgcag aaggcaaacc agaaaaaatc tgggacaaaa ttattccagg
    42421 taaaatggat cgcttcatgc ttgataacac taaagttgac caagcttaca cacttcttgc
    42481 acaagtttac atcatggatg acagcaagac agttgaagca taccttgaat cagttaacgc
    42541 ttcggtagtt gagtttgctc gctttgaagt tggtgaaggt atcgagaaag ctgcaaacga
    42601 cttcgaagct gaagttgcag ctacaatggc agcagccttg aataactaat aatagaaagg
    42661 aagcaaattg cttccttttt tgtatagggc ttagattttt cctgaaattg ttttttcccc
    42721 agtctcactc gattagaata attaaaacaa aaagccctat aataagggct aagggcattt
    42781 aggagactat acttcaaatt catagtaagc gcgttcataa caaggtatct atcctaattc
    42841 cccaacttcc agtatactag ataaaaaata attatcggag gaaaggtatt gtactatgat
    42901 aattcaacta agtgatttag gtcaagttca ccttgtttgt agcaagatag atatgaggca
    42961 gggaatagac tcattagcct atgtagttaa aacccacttt gaattggatc ctttctccgg
    43021 tcaagtcttt ctcttttgtg gtggacgtaa agaccgcttt aaagcccttt actgggatgg
    43081 tcaaggattt tggctactat ataaacgctt tgagaacgtc agactgactt ggcccagtac
    43141 agaaaaggat gtcaaagctc tcacacctga acaagtagac tggcttatga agggcttttc
    43201 tatcactcca aaaatatagt agattgaaac tagaatagta cacctctgct tctaaaacat
    43261 tgttagaaat cgatttgact gtcctgatcg atttgtcctg ttcttatttc attttactat
    43321 aaatccatca gaaagtcgtg atttctattg aaatgaggac tttcttttta tactcatctg
    43381 ttttcaaaaa gcattctagt ccatctccga ttaacgatgg actttatcac ctccttctcc
    43441 agtccttgta taacatcttg gagttgattc atgacatctt ccaaagtttg aaaggtttta
    43501 ttcttaaatc cacgtttacg aatctctttc cacacttgtt caatggggtt catctctggt
    43561 gtgtatggag gaataaatgc aaagccaata ttagtcggaa tctttaaggt acttgattta
    43621 tgccatatag cattgtccat aacgagtaaa agataatcat ctggataagc ttgtgaaatc
    43681 tcctattcct aaagcccctt tagcgcataa ctttggctca gcttctatta tcgctcacac
    43741 catccatcag aagtttaatc tgaaggtacc caattatcgc caagaagaag attgggctag
    43801 gatgggttta ccaatcacac gtaaggaaat ctctaatcgg catatcaaga cgagtcaata
    43861 ctatttggag cccctttata acctcttgcg agagagacta ttgactcagc ccttacttca
    43921 tgcggatgaa acttcttata gggtgctaga gagtgatagt cagctgactt actattggac
    43981 ttttttgtct gggaaagctg agaaacaagg gattacgctt taccatcatg tcctaatcga
    44041 tttgttcata tcttatttca atccattata aatagtgaga aatatctatc ctatcttcta
    44101 gaatgtcttc caaacgtgga aactctcgta aacaaagagg ttttagaggc ctatttacca
    44161 tggactaaag ttgtacaaga aaagtgcaaa taagaaatct ccagattagg aactatccgt
    44221 gagttctcta gtctggagat ttttcaatag acttcgttat tggacggtta caattcataa
    44281 agtgctgtag agagataacg ttcaccgtta tctggtgcta gggcaaggac ttttttacct
    44341 gtacctaatt ttttggcaac ctcgatggct ccgtagatag ctgcagctga ggaaatccct
    44401 acaaggaagc cttcttttcc accaatttca cgtccgagtg caagagcgtc atctgatgtt
    44461 acacgaacga taccatcata ggctttagta tcaagtgtat caggaataaa tccagctgag
    44521 ataccttgaa ttttgtgagg accaggtttt tcaccagata gaatagcaga ttcatctgct
    44581 tctactgcaa aaacttgaat gttagaattt tctgatttga gtgcatgaga aacaccagaa
    44641 atcgttccac cagtacctac tccagcaaca aaggcatcta atccatcttt accgaaagca
    44701 gctagtatct cagctcctgt tgttctttcg tgtacttctg gattagctgg attgtcaaat
    44761 tgaagaggaa ggaaaccatc acgttcagca gcgatttctt gagccttagc aatagcacct
    44821 ttcattccct cgctaccagg agttaggacg agttcagcac cataagcttg gataatttta
    44881 cgtcgttcta cactcatagt ttcaggcata acgatgacga ctttataccc tttagcagca
    44941 cctacccatg aaagtccaat accggtgttt ccacttgttg cttcaacaat agtagaacca
    45001 agtttcagaa taccatcttg ttcagctttt tcaatcatgc taagggcaat acggtctttt
    45061 acagatgaac caggattaaa tgcttcaagc tttatataga cgtctgcagc accttctggc
    45121 acgatgttgt taagtttaac aatcggtgtt tgaccgatta attcagtaat gttgttataa
    45181 atagacatat gaatacctct ttgtataaga tatctttagt ataacgctat ccataccatt
    45241 tgtaaaatat agaaatccta tcgaagcgat aggatttcta tatatcatag atcaaagtca
    45301 ttaattttca agtgattgcg ttcagttaat tctagtaaat aggtgtgaag gaaaacgata
    45361 tcaggtttcg tttgaattgc ttcattttct agtatatttt ggtacgcatc tttttatttt
    45421 gctcgctaaa gtagttgtga gaatgtcaac gaaacgctgt attattcatt gtttacacta
    45481 agtttacagg aacttcaacc tctcgtaaac cttggtcagt taaagtgact tttccattaa
    45541 aaaactccac aagtgcagct ttaatagttt ctttttcttc tttatcaaca taaatcatcg
    45601 tatcgacttg atctgtaaag tttgtatcca gctccatgag atcatgttct ttaaggaagt
    45661 tactgtactc ttggtactga gcataagaca tttgaatagc aatgccagcc tgttctttta
    45721 tttcaataat accaatttct ttgacagcta aggcgacact gccggcgtaa gcacgaatta
    45781 gtcctccagc gcctagttta ataccaccaa agtagcgtgt cacgaccaca cagacattgg
    45841 tgagattgtg attttctagt accccaagca tgggaacacc agcagtacca ctaggctcac
    45901 catcatcact tgtacgttta atttcactac gttctccaat aataaaggca gagcagttat
    45961 gtgtcgcttt gtagtgttct tttttgatgg cagtaatgaa gtcacgagcc tcttcttcgc
    46021 tataaacacg cttggcatgg cagataaagc gagatttttt gatttcttct tggacttggc
    46081 cgtcctcttt aattgtccta aattccatga tttaattgta ctaaaaaatc atctaaagtg
    46141 ctagttttta cgaataaaga agtatgaaag taaatttaga ttatctcggt cgtttattta
    46201 ctgagaatga attaacagaa gaagaacgtc agttggcgga gaaacttcca gcaatgagaa
    46261 aggagaaggg gaaacttttc tgtcaacgtt gtaatagcac tattctagca gaatggtatt
    46321 tgcccatcgg tgcttactat tgtcgagagt gcttgctgat gaagcgagtc agaagtgatc
    46381 aaactttata ctattttccg caggaggatt ttccgaagca agatgttctc aaatggcgcg
    46441 gccaattaac tccttttcaa gagaaggtgt cagagggact gcttcaagca gtagacaagc
    46501 aaaagccaac cttagttcat gcggtaacag gagctggaaa gacagaaatg atttatcaag
    46561 tagtggctaa agtgatcaat gcgggtggtg cagtgtgttt ggctagtcct cgcatagatg
    46621 tttgtttgga gctgtacaag cgcctgcaac aggatttttc ttgcgggata gctttgctac
    46681 atggagaatc ggaaccttat tttcgaacac cactagttgt tgcaacaacc catcagttat
    46741 tgaagtttta tcaagctttt gatttgctga tagtggatga agtagatgct tttccttatg
    46801 ttgataatcc cacgctttac catgctgtca agaatagtgt aaaggagaat ggattgagaa
    46861 tctttttaac agcgacttcg accaatgagt tagataaaaa ggtccgttta ggagaactaa
    46921 aaagactgaa tttaccgaga cggtttcatg gaaatccgtt gattattcca aaaccaattt
    46981 ggttatcgga ttttaatcgc tacttagaca agaatcgttt gtcaccaaag ttaaagtcct
    47041 atattgagaa gcagagaaag acagcttatc cgttactcat ttttgcttca gaaattaaga
    47101 aaggggagca gttagaagaa atcttacagg agcaatttcc aaatgagaaa attggctttg
    47161 tatcttctgt aacagaggat cgattagagc aagtacaagc ttttcgagat ggagaactga
    47221 caatacttat cagtacgaca atcttggagc gtggagttac cttcccttgt gtggatgttt
    47281 tcgtagtaga ggccaatcat cgtttgttta ccaagtctag tttgattcag attggtggac
    47341 gagttggacg aagcatggat agaccgacag gagatttgct tttcttccat gatgggttaa
    47401 atgcttcaat caagaaggcg attaaggaaa ttcagatgat gaataaggag gctggtctat
    47461 gaagtgcttg ttatgtgggc agactatgaa gactgtttta acttttagta gtctcttact
    47521 tctgaggaat gatgactctt gtctttgttc agactgtgat tctacttttg aaagaattgg
    47581 ggaagagaac tgtccaaatt gtatgaaaac agagttgtca acaaagtgtc aagattgtca
    47641 actttggtgt aaagaaggag ttgaagtcag tcatagagcg atttttactt acaatcaagc
    47701 tatgaaggat tttttcagtc ggtataagtt tgatggagac ttcctgttaa gaaaagtttt
    47761 cgcttcattt ttaagtgagg agttgaaaaa gtacaaagag tatcaatttg ttgtaattcc
    47821 cctaagtcct gatagatatg ctaatagagg atttaatcag gttgagggct tggtagaggc
    47881 agcaggcttt gagtatctgg atttattaga gaaaagagaa gagagagcca gttcttctaa
    47941 aaatcgttca gagcgcttgg ggacagaact tcctttcttt attaaaagtg gagtcactat
    48001 tcctaaaaaa atcctactta tagatgatat ctatactaca ggagcaacta taaatcgtgt
    48061 taagaaactg ttggaagaag ctggtgctaa ggatgtaaaa acattttccc ttgtaagatg
    48121 aggaaaaaat ttgcaaaaat agaatgaaag cgttataata aaatcataaa aacaaaaatg
    48181 tttagaaaga aggtactcat atgattaaat atagtatccg tggtgaaaac ctagaagtaa
    48241 cagaagcaat tcgtgattat gtagtttcta aactcgaaaa gatcgaaaag tacttccaac
    48301 cagaacaaga gttggatgcc cgaattaact taaaagttta tcgtgaaaaa acggctaaag
    48361 tggaagtaac gattccgctt ggatctatta ctctccgcgc agaagatgta tctcaagata
    48421 tgtatggttc aattgacctt gtaactgata aaattgaacg tcagattcgt aaaaataaaa
    48481 caaaaatcga gcgtaaaaat aaaaataagg tagcaactgg tcaattattt acagatgctt
    48541 tggtggaaga ttcaaatatt gtccagtcta aagttgttcg ttcaaaacaa attgatttaa
    48601 aaccaatgga tttggaagaa gcaattctac aaatggattt attggggcat gatttcttta
    48661 tctatgtgga tgttgaagat cagacaacca atgtgattta tcgtcgtgag gatggcgaaa
    48721 ttggtttgtt agaggttaaa gaatcttaat ttcaatatgt gtaaaggtag gtttactgaa
    48781 ttgtaaacta cctttttctt ataattgata gaattactga ttacactttt aaaaagtcgc
    48841 tttttgaggg gtattatggt ataatgggtg ccaagaggtt ttgaatgaaa aaattttatg
    48901 taagtccaat ttttcctatt ctagtaggat tgattgcgtt tggagtctta tccactttca
    48961 ttatttttgt taataataat ctgttgacgg ttttaatttt gtttcttttt gtaggaggct
    49021 atgttttttt atttaagaaa ctgagagtgc attatacaag gagtgatgta gaacagatac
    49081 agtatgtaaa ccaccaagcg gaagaaagtt tgacagctct attggaacag atgcctgtag
    49141 gtgttatgaa attgaattta tcttctggag aggttgagtg gtttaatccc tatgctgaat
    49201 tgattttgac caaggaagat ggtgattttg atttagaagc tgttcaaacg attatcaagg
    49261 cttcagtagg aaatccgtct acttatgcca agcttggtga gaagcgttat gctgttcata
    49321 tggatgcttc ttccggtgtt ttgtattttg tagatgtatc cagggaacaa gccataacag
    49381 atgaattggt aacaagtaga ccagtgattg ggattgtctc tgtggataat tatgatgatt
    49441 tggaggatgc aacttctgag tcagatatta gtcaaatcaa tagttttgta gctaatttta
    49501 tatcagagtt ttcagaaaaa tacatgatgt tttctcgtcg ggtaagtatg gatcgatttt
    49561 atctatttac tgactacacg gtgcttgagg gcttgatgaa tgataaattt tctgttattg
    49621 atgctttcag agaagagtcg aaacagagac agttgccctt gaccttaagt atgggatttt
    49681 cttatggcga tggaaatcat gatgagatag ggaaagttgc tttgctcaat ttgaacttgg
    49741 ctgaagtacg tggtggcgac caggtggttg ttaaggaaaa cgacgaaacg aaaaatccag
    49801 tttattttgg tggtgggtct gctgcttcaa tcaagcgtac acggactcgt acgcgcgcta
    49861 tgatgacagc tatttcagat aagattcgga gtgtagatca ggtttttgta gtcggtcaca
    49921 aaaatttaga catggatgct ttgggctctg ctgtaggtat gcagttgttc gccagcaatg
    49981 tgattgaaaa tagctatgct ctttatgatg aagaacaaat gtctccagat attgaacgag
    50041 ctgtttcatt catagaaaaa gaaggagtta cgaagttgtt gtctgttaag gatgcaatgg
    50101 ggatggtgac caatcgttct ttgttgattc ttgtagacca ttcaaagaca gccttaacat
    50161 tatcaaaaga attttatgat ttatttaccc aaaccattgt tattgaccac catagaaggg
    50221 atcaggattt tccagataat gcggttatta cttatatcga aagtggtgca agtagtgcca
    50281 gtgagttggt aacggaattg attcagttcc agaattctaa gaaaaatcgt ttgagtcgta
    50341 tgcaagcaag tgttttgatg gctggtatga tgttggatac taaaaatttc acctcgcgag
    50401 taactagtcg gacatttgat gttgctagct atctcagaac gcgcggaagt gatagtattg
    50461 ctatccagga aatcgctgcg acagattttg aagaatatcg tgaggtcaat gaacttattt
    50521 tacaggggtg taaattaggt tcagatgtac taatagcaga ggctaaggac acgaaatgct
    50581 atgatacagt tgttattagt aaggcagcag atgccatgtt agccatgtca ggtattgaag
    50641 cgagttttgt tcttgcgaag aatacacaag gatttatctc tatctcagct cgaagtcgta
    50701 gtaaactgaa tgtacaacgg attatggaag agttaggcgg tggaggccac tttaatttgg
    50761 cagcagctca aattaaagat gtaaccttgt tagaagcagg tgaaaaactg acagaaattg
    50821 tattaaatga aataaaggaa aaggagaaag aagaatgaaa gtaatctttt tagcagatgt
    50881 taaaggaaaa ggtaaaaaag gcgaaattaa ggaagtacca acagggtatg cgcaaaactt
    50941 tcttatcaaa aagaatctag ccaaagaagc gactgctcaa gctgtaggtg aacttcgtgg
    51001 taaacaaaaa tcggaagaaa aagctcacgc tgagatgatt gcagaaggaa aagcaattaa
    51061 agcacaactt gaagcagaag aaactgttgt agaatttgtt gaaaaagttg gtccagatgg
    51121 tcgtaccttt ggttctatta ccaataagaa gattgcagaa gaattgcaaa agcaatttgg
    51181 aattaagatt gataaacgtc atattcaagt acaagctccg attcgagcgg ttggtttgat
    51241 tgatgtgcca gtgaaaatct atcaagatat cacaagtgta atcaatcttc gtgtgaaaga
    51301 aggataagtt tacaccttct tgacaagatt gtaaaaggaa gggaagtctg atggcagaag
    51361 tagaagagtt acgagtacaa cctcaagata tcttagctga gcaatccgtt ttaggggcta
    51421 tctttattga tgagagtaaa cttgtttttg tgcgagaata cattgagtct cgggactttt
    51481 ttaagtatgc ccatcgtttg attttccaag ccatggtcga tttatccgat cgtggtgatg
    51541 ccatagatgc aacaacggtt cgtactatcc ttgataatca aggtgattta cagaatattg
    51601 gtggcttgtc ttacttggtt gagattgtca attctgtgcc aacttctgct aatgcggagt
    51661 attatgctaa gattgttgca gaaaaagcaa tgctacgtcg tttaattgcc aagttgacag
    51721 agtctgtcaa ccaagcttac gaagcgtcac aaccagctga tgaaattatt gctcaggcag
    51781 aaaaagggct gattgatgtc agtgaaaatg caaatcgaag cgggtttaag aacattcgag
    51841 atgtgttgaa tctcaacttt ggaaatctgg aagctcgctc gcaacaaacg accgatatta
    51901 caggtattgc gacaggttat cgtgatttgg atcatatgac aacaggactt catgaggagg
    51961 agttgattat cttagcagct cgtccagcag ttggtaagac agcatttgcc ttgaatatcg
    52021 ctcagaatat tgggactaag ttggacaaaa cggttgctat tttttcactc gaaatgggtg
    52081 cggaaagctt ggtagaccgt atgttagctg cagaaggctt ggtggagtca cattctatcc
    52141 gtacagggca attgacagat gaggagtggc aaaaatatac tattgctcag ggtaatctag
    52201 ctaacgccag tatctatatc gatgatacgc caggtattcg gattacagag attcgttctc
    52261 gttctcgtaa attggctcaa gaaactggaa atcttggttt gattttgata gactatttgc
    52321 aacttatcac gggaactggt cgagaaaatc gtcaacaaga agtttctgaa atttctcgtc
    52381 agttgaaaat actagccaag gaattgaagg ttccagtaat cgctctgagt cagctttctc
    52441 gtggtgtaga acaacgtcag gacaagagac cggtcttgtc tgatattcgt gaatctgggt
    52501 ctattgagca ggacgctgat atcgtagctt ttctctatcg cgatgactac tatgaacgtg
    52561 gtggtgaaga agaggagggt atcccaaata ataaggtgga agttattatc gagaaaaacc
    52621 gtagtggagc tcgtggaaca gtggaattga ttttccaaaa agaatacaat aaattttcaa
    52681 gtatctcaaa gagggaggca taagatgtca gatgcattta cagatgtagc caagatgaaa
    52741 aaaatcaaag aagaaatcaa ggcacatgag ggacaagtcg tagaaatgac tttggagaat
    52801 ggtcgtaagc gccaaaaaaa tagattgggt aagctaattg aagtttatcc atccctattt
    52861 attgtggagt ttggggatgt ggaaggagat aaacaagtta atgtttacgt tgaatccttt
    52921 acttactcag atattcttac agaaaagaat ttgattcatt atcttgacta aagtgagaaa
    52981 ttttctcact ttttcttttt tctccgaata atttaggtga aggcaatcat cgctttatat
    53041 tattttttaa ggaggaagaa tgaaaatttt accgtttata gcaagaggaa caagttatta
    53101 cttgaagatg tcagttaaaa agcttgttcc ttttttagta gtaggattga tgctagcagc
    53161 tggtgatagt gtctatgcct attccagagg aaatggatcg attgcgcgtg gggatgatta
    53221 tcctgcttat tataaaaatg ggagccagga gattgatcag tggcgcatgt attctcgtca
    53281 gtgtacttct tttgtagcct ttcgtttgag taatgtcaat ggttttgaaa ttccggcagc
    53341 ttatggaaat gcgaatgaat ggggacatcg tgctcgtcgg gaaggttatc gtgtagataa
    53401 tacaccgacg attggttcca ttacttggtc tactgcagga acttatggtc atgttgcctg
    53461 ggtgtcaaat gtaatgggag atcagattga gattgaggaa tataactatg gttatacaga
    53521 atcctataat aaacgaatta taaaagcaaa cacgatgaca ggatttattc attttaaaga
    53581 tttggatggt ggcagtgttg ggaatagtca atcctcaact tcaacaggcg gaactcatta
    53641 ttttaagacc aagtctgcta ttaaaactga acccctagtt agtgcaactg tgattgatta
    53701 ctattatcct ggagagaagg ttcattatga tcaaattctc gaaaaagacg gctacaagtg
    53761 gttgagttat actgcctata atggaagcta tcgttatgtt caattggagg ctgtgaataa
    53821 aaatcctcta ggtaattctg ttctttcttc aacaggtgga actcattatt ttaagaccaa
    53881 gtctgctatc aaaactgaac ccctagttag tgcaactgtg attgattact attatcctgg
    53941 ggagaaggtt cattatgatc agatacttga aaaagacggc tacaagtggt tgagttatac
    54001 ggcttataac ggaagtcgtc gctatataca gctagaggga gtgacttctt cacaaaatta
    54061 tcagaatcaa tcaggaaata tctctagcta tggatccaat aatagttcaa ctgtcggttg
    54121 gaagaaaata aatggtagtt ggtatcattt caaatcaaat ggttctaaat caacaggatg
    54181 gctgaaagat ggttctagct ggtattattt gaaattatct ggtgaaatgc agacaggatg
    54241 gttaaaggag aatggctcgt ggtattatct gggtagttca ggggcaatga aaacaggctg
    54301 gtaccaggtc tctggtaagt ggtattattc ttactcttca ggcgccttag ctgttaatac
    54361 gacggtggat ggctacagag taaacagtga tggagaacga gtatagaaaa ttggagtagg
    54421 agaaatttcc tgctcttttc tgtaagcagt ttccttgaca tttttcttat tttgcgctat
    54481 catatataca tataatatat gggagtctgt gtacagtctg agaggaagtg ttaaacttcg
    54541 accgcacctg atctgggtaa tgccagcgga gggaacgata cttagtctaa ttttgcacct
    54601 tttccatgta tggtaaaggt ttttcttttt ttaaaaagga aaacgagaag aggaggttct
    54661 tatgaaagca agcattgcct tgcaagtttt acccctagca caggggattg atcggatagc
    54721 tgttattgat caggtcattg cttatctgca aactcaagaa gtgacgatgg tagtgacacc
    54781 atttgaaacg gtcttggaag gggagtttga tgagcttatg cgcattctaa aagaagcgct
    54841 ggaagtggca gggcaggagg cagacaatgt ctttgccaat gtcaaaataa atgtaggaga
    54901 gattttaagt attgatgaga aacttgagaa gtatactgag acgccacatt agtctattgg
    54961 gctttctcgg agtcttgtca atctggcagt tagcaggttt tcttaaactt ctccccaagt
    55021 ttatcctgcc gacacctctt gaaattctcc agccctttgt tcgtgacaga gaatttctct
    55081 ggcaccatag ctgggcgacc ttgagagtgg ctttactggg gctgattttg ggagttttga
    55141 ttgcctgtct tatggctgtg ctcatggata gtttgacttg gctcaatgac ctgatttacc
    55201 ctatgatggt ggttattcag accattccga ccattgccat agctcctatc ctggtcttgt
    55261 ggctaggtta tgggattttg cccaagattg tcttgattat cttaacgaca acttttccca
    55321 tcatcgtcag cattttggac ggttttaggc attgcgacaa ggatatgctg accttgttta
    55381 gtctgatgcg ggccaagcct tggcaaatcc tgtggcattt taaaattcca gtcagcctgc
    55441 cctactttta tgctggtctg agggtcagtg tctcctacgc ttttatcaca acagtggtat
    55501 ctgagtggtt gggaggtttt gaaggtcttg gtgtttatat gattcagtct aaaaaactgt
    55561 ttcagtatga taccatgttt gccattatta ttctggtgtc gattatcagt cttttgggta
    55621 tgaagctggt cgatatcagt gaaaaatatg tgattaaatg gaaacgtact taaaatagag
    55681 cgtttttgaa aaagaaaaga ggaaatcaaa atgaagaaaa catggaaagt gtttttaacg
    55741 cttgtaacag ctcttgtagc tgttgtgctt gtggcctgtg gtcaaggaac tgcttctaaa
    55801 gacaacaaag aggcagaact taagaaggtt gactttatcc tagactggac accaaatacc
    55861 aaccacacag ggctttatgt tgccaaggaa aaaggttatt tcaaagaagc tggagtggat
    55921 gttgatttga aattgccacc agaagaaagt tcttctgact tggttatcaa cggaaaggca
    55981 ccatttgcag tgtatttcca agactacatg gctaagaaat tggaaaaagg agcaggaatc
    56041 actgccgttg cagctattgt tgaacacaat acatcaggaa tcatctctcg taaatctgat
    56101 aatgtaagca gtccaaaaga cttggttggt aagaaatatg ggacatggaa tgacccaact
    56161 gaacttgcta tgttgaaaac cttggtagaa tctcaaggtg gagactttga gaaggttgaa
    56221 aaagtaccaa ataacgactc aaactcaatc acaccgattg ccaatggcgt ctttgatact
    56281 gcttggattt actacggttg ggatggtatc cttgctaaat ctcaaggtgt agatgctaac
    56341 ttcatgtact tgaaagacta tgtcaaggag tttgactact attcaccagt tatcatcgca
    56401 aacaacgact atctgaaaga taacaaagaa gaagctcgca aagtcatcca agccatcaaa
    56461 aaaggctacc aatatgccat ggaacatcca gaagaagctg cagatattct catcaagaat
    56521 gcacctgaac tcaaggaaaa acgtgacttt gtcatcgaat ctcaaaaata cttgtcaaaa
    56581 gaatacgcaa gcgacaagga aaaatggggt caatttgacg cagctcgctg gaatgctttc
    56641 tataaatggg ataaagaaaa tggtatcctt aaagaagact tgacagacaa aggcttcacc
    56701 aacgaatttg tgaaataatg acagaaatta gactagagca cgtcagttat gcctatggtc
    56761 aggagaggat tttagaggat atcaacctac aggtgacttc aggcgaagtg gtttccatcc
    56821 taggcccaag tggtgttgga aagaccaccc tctttaatct aatcgctggg attttagaag
    56881 ttcagtcagg gagaattgtc cttgatggtg aagaaaatcc caaggggcgc gtgagttata
    56941 tgttgcaaaa ggatctgctc ttggagcaca agacggtgct tggaaatatc attctgcccc
    57001 tcttgattca aaaggtggat aaggcagaag ctatttcccg agcggataaa attcttgcga
    57061 ccttccagct gacagctgta agagacaagt atcctcatga acttagcggt gggatgcgcc
    57121 agcgtgtagc cttactccgg acctaccttt ttgggcacaa gctctttctc ttagatgagg
    57181 cctttagcgc cttggatgag atgacaaaga tggaactcca cgcttggtat cttgagattc
    57241 acaaacagtt gcagctaaca actctgatca tcacgcatag tattgaggag gccctcaatc
    57301 tcagcgaccg catctatatc ttgaaaaatc gccctgggca gattgtttca gaaattaaac
    57361 tagattggtc tgaagatgag gacaaggaag tccaaaagat tgcctacaaa cgtcaaatct
    57421 tggcagaatt aggcttagat aagtagaaaa atagggagtt ggtgaagatt atcctttacc
    57481 agcgcccttt ttcttttaaa aatgagaaaa tttcggtata atagtcaaac aaggtcaagg
    57541 tttaaagaga gaggtgggtt tgttatgaga tttaaaaata catcggatca tattgaggcc
    57601 tacatcaagg cgattttaga tcaatctggt atcgtggagt tgcaacggag tcagttggca
    57661 gatacctttc aggttgttcc tagtcagatt aactacgtga tcaagacacg ctttacggaa
    57721 agtagaggct acttggttga aagtaagcgt ggtggcggag gctacattcg tataggacgg
    57781 attgagtttt ctagtcatca tgaaatgctc cgggatctgc tttactcgat tggtgagcga
    57841 gtcagtcaag aaatttatga ggatattctc cagcttttgg ttgagcagga attgatgacc
    57901 aagcaggaga tgaatttgct agaatcagta gctttggatc gcgttttagg agaagaagct
    57961 ccagttgttc gagcaaacat gctacgtcag gtcatacaag aggtagatag aaaagggaag
    58021 taagatgaac tattcaaaag cattgaatga atgtatcgaa agtgcctaca tggttgctgg
    58081 acattttgga gctcgttatc tagagtcgtg gcacttgttg attgccatgt ctaatcacag
    58141 ttatagtgta gcaggggcaa ctttaaatga ttatccgtat gagatggacc gtttagaaga
    58201 ggtggctttg gaactgactg aaacggacta tagccaggat gaaaccttta cggaattgcc
    58261 gttctcccgt cgtttgcagg ttctttttga tgaagcagag tatgtagcgt cagtggtcca
    58321 tgctaaggta ctagggacag agcacgtcct ctatgcgatt ttgcatgatg gcaatgcctt
    58381 ggcgactcgt atcttggaga gggctggttt ttcttatgaa gacaagaaag atcaggtcaa
    58441 gattgctgcc cttcgtcgaa atttagaaga acgtgcaggc tggactcgtg aagatctcaa
    58501 ggctttacgc caacgccatc gtacagtagc tgacaagcaa aattctatgg ccaatatgat
    58561 gggcatgccg cagactccta gtggtggtct cgaggactat acgcatgatt tgacagagca
    58621 agcgcgttct ggcaagttag aaccagtcat cggtcgggac aaggaaatct cgcgtatgat
    58681 tcaaatattg agccgtaaga ctaagaacaa ccctgtcttg gttggggatg ctggtgtcgg
    58741 gaaaacagct ctggcccttg gtcttgccca gcgtattgct agtggtgacg tgcctgcgga
    58801 aatggctaag atgcgcgtgt tagaacttga tttgatgaat gtcgttgcag ggacacgctt
    58861 ccgtggtgac tttgaagaac gcatgaataa tatcatcaag gatattgaag aagatggcca
    58921 agtcatcctc tttatcgatg aactccacac catcatgggt tctggtagcg ggattgattc
    58981 gactctggat gcggccaata tcttgaaacc agccttggcg cgtggaactt tgagaacggt
    59041 tggtgccacc actcaggaag aatatcaaaa acatatcgaa aaagatgcgg ctctttctcg
    59101 tcgtttcgct aaagtgacga ttgaagaacc aagtgtggca gatagtatga ctattttaca
    59161 aggtttgaag gcgacttatg agaaacatca ccgtgtacaa atcacagatg aagcggttga
    59221 aacagcggtt aagatggctc atcgttattt aaccagtcgt cacttgccag actctgctat
    59281 cgacctcttg gacgaagcag cagcaacagt gcaaaataag gcaaagtatg taaaagcaga
    59341 cgattcagat ttgagtccag ctgacaaggc cctgatggat ggcaagtgga aacaggcagc
    59401 ccagctaatc gcaaaagaag aggaagtacc tgtctacaaa gacttggtga cagagtctga
    59461 tattttgacc accttgagtc gcttgtcagg aatcccagtt caaaaactga ctcagactga
    59521 cgctaagaaa tatctaaatc ttgaagcaga actccataaa cgggttatcg gtcaagatca
    59581 agctgtttca agtattagtc gtgcgattcg ccgtaatcag tcaggaattc gcagtcacaa
    59641 gcgtccgatc ggttccttta tgttcctagg acccacaggt gtcggtaaga ccgagttggc
    59701 caaggctttg gcagaagttc tctttgatga cgaatcagcc cttatccgct ttgatatgag
    59761 tgagtatatg gagaaattcg cagccagccg tctaaatgga gctcctccag gctatgtggg
    59821 ttacgaagaa ggtggggagt tgacagagaa ggttcgcaat aaaccctatt ccgttctcct
    59881 ctttgatgag gtagagaagg ctcacccaga tatctttaat gttctcttgc aggttctgga
    59941 tgacggtgtc ttgacagata gcaagggacg caaggtcgat ttttcaaata ccattatcat
    60001 tatgacatcg aacctaggtg cgactgccct tcgtgatgat aagactgttg gttttggggc
    60061 taaggatatt cgttttgacc aggaaaatat ggaaaaacgc atgtttgaag aactgaaaaa
    60121 agcttataga ccggaattca tcaaccgtat tgatgagaag gtggtcttcc atagcctatc
    60181 tagtgaccat atgcaggaag tggtgaagat tatggtcaag cctttagtgg caagtttggc
    60241 tgaaaaaggc attgacttga aattacaagc ttcagctctg aaattgttag caaatcaagg
    60301 atatgaccca gagatgggag ctcgcccact tcgcagaacc ctgcaaacag aagtggagga
    60361 caagttggca gaacttcttc tcaagggaga tttagtggca ggcagcacac ttaagattgg
    60421 tgtcaaagca ggccagttaa aatttgatat tgcataaaag aataaaagta tcagcatctg
    60481 accataagtc acagtggagt gaaactcaat gaaaatcaaa gaacaaacta ggcagctagc
    60541 cgcaggttgc tcaaaacact gttttgaggt tgtagataga gctgacgtgg tttggagaga
    60601 ttttcgaaga gtataagctg caagatgaat gattttcttg tattgacgtt gttgttgaca
    60661 aaaagtagcg gataaatgaa atccattcca ttatcataga tgataggctg gtaggaaatt
    60721 ttcaaatagc atacaggaaa tagatgtatg gagttctggt agtagaaagg gagagagatg
    60781 aacattttag ttgcagatga cgaggaaatg attagagaag gaattgcagc atttctgaca
    60841 gaagagggtt atcatgtcat tatggctaag gatggacaag aggtcttgga aaaatttcaa
    60901 gatctcccta tccatctcat ggtattggat ttaatgatgc ctaggaagag tggttttgaa
    60961 gtgttaaaag aaatcaatca aaagcacgat attcctgtca tcgtcttgag tgctctggga
    61021 gatgaaacta ctcagtcaca ggtatttgat ctctatgctg atgatcatgt gacaaaacct
    61081 ttttctttgg tactgcttgt caagcgtatt aaggcgctta tcagacgtta ctacgtcata
    61141 gaggatattt ggcgatatca ggatgtaaca gtggatttta cctcttacaa agcacattat
    61201 aaaaatgaag aaattgatct caaaccaaag gaattactgg tactaaagtg tttgattcag
    61261 cataaaaatc aagttttaag tagagagcag atattggaag aaatttcaaa agatgtagct
    61321 gatttacctt gtgatagggt cgttgatgtc tatattcgta ctcttcgcaa aaaattagct
    61381 ttagattgta tcgtgactgt gaaaaatgtt gggtataaga ttagcttatg ataaaaaatc
    61441 ctaaattatt aaccaagtct tttttaagaa gttttgcaat tctaggtggt gttggtctag
    61501 tcattcatat agctatttat ttgacctttc ctttttatta tattcaactg gagggggaaa
    61561 agtttaatga gagcgcaaga gtgtttacgg agtatttaaa gactaagaca tctgatgaaa
    61621 ttccaagctt actccagtct tattcaaagt ccttgaccat atctgctcac cttaaaagag
    61681 atattgtaga taagcggctc cctcttgtgc atgacttgga tattaaagat ggaaagctat
    61741 caaattatat cgtgatgtta gatatgtctg ttagtacagc agatggtaaa caggtaacag
    61801 tgcaatttgt tcacggggtg gatgtctaca aagaagcaaa gaatattttg cttttgtatc
    61861 tcccatatac atttttggtt acaattgctt tttcctttgt tttttcttat ttttatacta
    61921 aacgcttgct caatcctctt ttttacattt cagaagtgac tagtaaaatg caagatttgg
    61981 atgacaatat tcgttttgat gaaagtagga aagatgaagt tggtgaagtt ggaaaacaga
    62041 ttaatggtat gtatgagcac ttgttgaagg ttattcatga gttggaaagt cgtaatgagc
    62101 aaattgtaaa attgcaaaat caaaaggttt cctttgtccg cggagcatca catgagttga
    62161 aaaccccttt agccagtctt agaattatcc tagagaatat gcagcataat attggagatt
    62221 acaaagatca tccaaaatat attgcaaaga gtataaataa gattgaccag atgagccact
    62281 tattggaaga agtactggag tcttctaaat tccaagagtg gacagagtgt cgtgagacct
    62341 tgactgttaa gccagtttta gtagatattt tatcacgtta tcaagaatta gctcattcaa
    62401 taggtgttac aattgaaaat caattgacag atgctaccag ggtcgtcatg agtcttaggg
    62461 cattggataa ggttttgaca aacctgatta gtaatgcaat taaatattca gataaaaatg
    62521 ggcgcgtaat catatccgag caagatggct atctctctat caagaataca tgtgcgcctc
    62581 taagtgacca agaactagaa catttatttg atatattcta tcattctcaa atcgtgacag
    62641 ataaggatga aagttccggt ttgggtcttt acattgtgaa taatatttta gaaagctatc
    62701 aaatggatta tagttttctc ccttatgaac acggtatgga atttaagatt agcttgtaga
    62761 cagattagtt ttttattaaa gttcatatag ggttaacata agtgtgttat tctttgtgta
    62821 gataaaagaa aggatactaa tatggtatta gcgattattt tagtaacatt ctttattcga
    62881 ttgatttttt taaagcgttc gatagagaat gagaaacgaa tccttagcaa tggcgggaaa
    62941 gaatttggag ttgagaatac aaaacgatta actatggctc atattgtttt ttatctctct
    63001 tgcttggttg aggcaatggt gcacaagaca atttttgatg gcatgggcat ggttggttta
    63061 gtcttgctta ttttttctat gctgatgttg atgttggtga ttcacttgtt gggagatatt
    63121 tggacagtga agcttatgct tgtcaataat cacaaatatg tagatcatat cttgtttagg
    63181 acagtaaaac atcctaatta ctttttaaat attcttcctg agttgattgg cttgaccttg
    63241 ttgagtcatg cttatgtgac ttttgtttta gtttttccag tttatgcagt tattttgtat
    63301 cgacgaatag ctgaagagga aaagctatta catgaagtta taatcccaaa tggaagcata
    63361 aagagataaa tacaaaattc gatttatata cagttcatat tgaagtgata tagtaaggtt
    63421 aaagaaaaaa tatagaagga aataattatg tttgcatcaa aaagcgaaag aaaagtacat
    63481 tattcaattc gtaaatttag tgttggagta gctagtgtag tagttgctag cttgttctta
    63541 ggaggagtag tccatgcaga aggggttaga agtggggata cccccaaggt tacatctagt
    63601 gggcaagata tatcgaagaa gtatgctgat gaagtcaagt cgcatctaga aaaaatattg
    63661 agtgagatcc aattagataa aagaaaacat acccaaaatc tcgccttcaa caaaaagttg
    63721 agcagaattc aaacggagta tttctattta aaaaagaagt tgaaagctga gttgacgtca
    63781 aaaacaaaag aagagttaac gtcaaaaaca gaagagttga cgtcaaaaac aaaaaaagag
    63841 ttagacgcag cttttgagca gtttaaaaaa gatacattat caacagaacc agaaaaaaag
    63901 gttgcagaag ctcagaagaa ggtagcagaa gctaagaaga aggtagcaga agctaagaaa
    63961 aaagccgagg atcaaaaaga agaagatcgt cgtaactacc caaccaatac ttacaaaacg
    64021 cttgaacttg aaattgctga gttcgatgtg aaagttaaag aagcggagct tgaactatta
    64081 aaagagaaag ctaaggaatc tcgagacgag gaaaaaatta agcaagcaga agcggaagtt
    64141 gagagtaaac aagctgaggc tacaaggtta gaaaacatca agacagatcg taaaaaagca
    64201 gaagaagcta aacgaaaagc agatgctaag ttgaaggaag ctaatgtagc gacttcagat
    64261 caaggtaaac caaaggggtg ggcaaaacga ggagttcctg gagagctagc aacacctgat
    64321 aaaaaagaaa atgatgcgaa gtcttcagat tctagcgtag gtgaagaaac tcttccaagc
    64381 tcatccctga aatcaggaaa aaaggtagca gaagctgaga agaaggttga agaagctgag
    64441 aaaaaagcca aggatcaaaa agaagaagat cgccgtaact acccaaccaa tacttacaaa
    64501 acgcttgaac ttgaaattgc tgagtccgat gtgaaagtta aagaagcgga gcttgaacta
    64561 gtaaaagagg aagctaagga acctcgagac gaggaaaaaa ttaagcaagc aaaagcggaa
    64621 gttgagagta aacaagctga ggctacaagg ttagaaaaaa tcaagacaga tcgtaaaaaa
    64681 gcagaagaag aagctaaacg aaaagcagca gaagaagata aagttaaaga aaaaccagct
    64741 gaacaaccac aaccagcgcc ggctcctcaa ccagaaaaac cagctccaaa accagaaaaa
    64801 ccagctccag ctccaaaacc agagaatcca gctgaacaac caaaagcaga aaaaccagct
    64861 gatcaacaag ctgaagaaga ctatgctcgt agatcagaag aagaatataa tcgcttgact
    64921 caacagcaac cgccaaaaac tgaaaaacca gcacaaccat ctactccaaa aacaggctgg
    64981 aaacaagaaa acggtatgtg gtacttctac aatactgatg gttcaatggc gacaggatgg
    65041 ctccaaaaca atggctcatg gtactacctc aacagcaatg gcgctatggc gacaggatgg
    65101 ctccaaaaca atggttcatg gtactatcta aacgctaatg gttcaatggc aacaggatgg
    65161 ctccaaaaca atggttcatg gtactacctc aacgctaatg gttcaatggc gacaggatgg
    65221 ctccaaaaca atggttcatg gtactacctc aacgctaatg gtgatatggc gacaggatgg
    65281 ctccaaaaca atggctcatg gtactaccta aacgctaatg gtgatatggc gacaggatgg
    65341 ctccaaaaca acggttcatg gtactaccta aacagcaatg gtgctatggt aacaggatgg
    65401 ctccaaaaca atggctcatg gtattacctc aacgctaatg gtgatatggc gacaggttgg
    65461 gtgaaagatg gagacacctg gtactatctt gaagcatcag gtgctatgaa agcaagccaa
    65521 tggttcaaag tatcagataa atggtactat gtcaatggct caggtgccct tgcagtcaac
    65581 acaactgtag atggctatgg agtcaatgcc aatggtgaat gggtaaacta aacctaatat
    65641 aactatttaa tactgacttc ctgtaagaac tttttaaagt attccctaca aataccatat
    65701 cctttcagta gataatatac ccttgtagga agtttagatt aaaaaataac tctgtaatct
    65761 ctagccggat ttatagcgct agagactacg gagttttttt gatgaggaaa gaatggcggc
    65821 attcaagaga ctctttaaga gagttacggg ttttaaacta ttaagccttc tccaattgca
    65881 agagggcttc aatctctgct agggtgctag cttgcgaaat ggctccacgg agtttggcag
    65941 cgccagatgt tccacggaga tagtgaggag cgaggccgcg gaattcacga actgcgacgt
    66001 tttctccttt gaggttaatc aatcgtttca agtgttcgta ggcgatcttc atcttgtctt
    66061 caaaggtcaa atcaggtagg atttctcctg tttcaaagta atggttgatt tggttgaaga
    66121 ggtaaggatt tcccatggca gctcggccaa tcatgactgc gtcagcacca acttcttcga
    66181 tgcgttgctt ggcttcttgg acagtacgga tatcaccgtt ggcgatgaat ggaatcttgg
    66241 ttagagcttg ggcaaccttg taaagggtct caaggtctgc gtggccagta tacatttgtt
    66301 cacgggtacg gccatgcatg gcgagggcag aaacacctgc agcttcagca gcgagggcat
    66361 tttctactgc cagagatgga tccgcccagc cggtacgcat tttgacagta agtgggatat
    66421 caaggacaga ctggaccttg ttgatgatgg agtaaatctt gtctggatcc ttgagccaca
    66481 tagcaccagc ttcgttcttc acgattttgt tgacagggca gcccatgttg atatcgacga
    66541 tatcggtctt ggtgttttct tggatgaatt ctgctgcgcg tgctaggctg tcttcatcgc
    66601 taccaaaaag ttggatagag acagggtttt cgccctcatc gatatgaagc atgtgcaggg
    66661 ttttttcgtt gttgtattgg attcccttgt cagagaccat ttccattaca acgagtccag
    66721 ctccgagctc ttttgcgatg gtacgaaagg ctgagttggt cacgccagcc ataggcgcta
    66781 aaacggtacg attgggaatc tcaacattgc caatcataaa aggtgtatta agatttgtca
    66841 cgaatgagtt cctccaggtc cttttcatca aagttgtaag tagtttggca gaattgacaa
    66901 gtgatttctg ccccgtggtc ttcttctttc atttcctgta agtctgagct tggaaggctg
    66961 gcaagagcgt tcataaagcg ttcatggcta cagtcacatt ggaaacggat ttcttcttca
    67021 gaaagacgct tgtaggcttc gtccccgtag atagccttga ggagggcttc gatatggtcg
    67081 tcgctttcga gaagagtaga gatagctggc atttcttgga tgcgtttttc aaagcgagca
    67141 atctcttctt tcttggctcc tggcaagact tgaactagga aaccacctgc aaccttgacc
    67201 ttgtcttcct cgtccaaaag gacattgagg ccgaccgctg aaggcgtttg ttggctttca
    67261 gtaaggtaaa aggcaaggtc ttcaccgatt tctccagaga tgaggggagt tatagagttg
    67321 taaggatttc cagtaccgta gtctgtgata acgaggaatt gaccatttcc aacaaaaggt
    67381 ccgactagga cttcaccagt cgcagtcttt ttgatgtcaa caccaggatt ttgaacgtag
    67441 cctttgacgt tccccttggt atcagcgacg gtgataatag cacctagaga gctagatccc
    67501 aacaccttaa ctgtaagttt ggtatttcct ttttcattgg ctgcgagaat ctggctggcg
    67561 ataagagttc gaccaagcgc tacagttgag ctagcttggg tttgatgttt ttcttgagca
    67621 gtgcggacgg tttcagtgct atcaaggaca aaagcacgaa aggctccgct ttctgatata
    67681 gttttaataa ttttatccat agctactatt ttagcataaa aatgcccaaa gggggagccg
    67741 tgtgtttact gattttcagg ataatggacc aggaaatcag catgaaaata aaaagagaaa
    67801 cagattattt tagcatttgt aagatttatg ctatgcttaa ggtagaaaat gaaaggggta
    67861 acaaatgtat ttaggagatt tgatggagaa agccgagtgt ggtcaatttt caatcctttc
    67921 ctttctatta caagagtctc agacgaccgt caaggctgta atggaagaaa caggattttc
    67981 aaaagcaacc ctaaccaaat atgtcaccct gctcaatgac aaggctttgg atagtggctt
    68041 agagctggct attcactcag aagatgaaaa tctgcgtctg tctatcggtg cagctaccaa
    68101 ggggagagat attcggagct tgtttttgga gagtgctgtt aaataccaga ttttggttta
    68161 tcttctctac caccaacagt ttttagccca tcagctggct caagaattgg tgattagcga
    68221 ggctacgctt ggtcgtcact tggctggttt aaatcagatt ttgtcagaat ttgatttatc
    68281 catccaaaat ggacgttggc gaggtccaga gcatcagatt cgctatttct atttctgtct
    68341 tttccgaaag gtctggtcga gtcaggaatg ggaaggtcac atgcagaaac cagagagaaa
    68401 acaggagatt gccaatttag aggaaatctg cggtgcaagt ttgtctgtgg ggcagaaatt
    68461 ggacttggtt ctctgggctc acatcagtca acaacgtctt cgggtcaatg cttgtcagtt
    68521 tcaagtcata gaagagaaaa tgcgagggta ttttgacaat atcttctatc ttcgtttgct
    68581 gagaaaggtt ccgtcctttt ttgctgggca acatattcca ctaggagttg aggatggtga
    68641 gatgatgata ttcttctctt ttctcctatc tcatcgcatt cttcctcttc atactatgga
    68701 atatattctt ggttttggag ggcagttggc agatttactg acgcaattga ttcaagaaat
    68761 gaagaaggag gaactattgg gggattatac agaggaccat gtcacctatg aactcagtca
    68821 gctttgtgct caagtctatc tctataaggg ctatatttta caggatcgct acaagtacca
    68881 gttagagaat cgtcatccat atttactgat ggaacatgat tttaaagaga cagcagagga
    68941 gatttttcat gctctacctg cttttcaaca ggggacagat ttagataaga agattctctg
    69001 ggaatggctc cagttaatcg aatatatggc tgaaaacggt ggccagcata tgcggattgg
    69061 tctggatttg acatctggtt ttcttgtctt ttcaaggatg gcagccattt tgaaacggta
    69121 tttggaatac aatcgtttta ttaccattga agcttatgac cctagtcggc attatgattt
    69181 gctggttacc aataacccga ttcataagaa ggaacagacc ccagtctatt atttaaaaaa
    69241 tgacttggat atggaagatt tggcagggat tcgtcagtta ttattcactt aaaaggcttg
    69301 gttaatccag gtcttttttg tgaaattcac acaatctcct cacatttttt taaaaattaa
    69361 aaaaagttga taaacaagaa agcgctttat tttgtatact agtaagtgta aagaggaaac
    69421 acctcaagat ctttatcagg aggacagtac atgtcacaag aaaaatacat catggccatt
    69481 gaccagggaa ctacaagttc tcgtgccatc attttcaaca aaaaagggga aaaggttagc
    69541 tcgagtcaaa aagagtttac ccagattttc cctcaggcag gttgggttga gcacaatgcc
    69601 aatgaaattt ggaactctgt tcagtcagtt attgcgggtg ctttcatcga aagtggtgtc
    69661 aagccaaatc aaatcgaggc aatcgggatt accaaccaac gtgaaacaac ggttgtctgg
    69721 gataagaaaa caggacttcc tatctacaat gctatcgttt ggcagtcacg ccagacagca
    69781 cctttggctg agcaactaaa aagccaaggt tatgtggaaa aattccatga aaagactggt
    69841 ttgattattg atgcttactt ctctgctacc aaggttcgtt ggattttgga tcatgtagaa
    69901 ggcgctcaag agcgagcaga aaaaggggaa ttgctctttg gtactatcga tacttggttg
    69961 gtttggaaat tgactgacgg tgcggctcac gtgactgact actcaaatgc agctcgtacc
    70021 atgctttata acattaaaga actcaaatgg gatgatgaga ttttggaaat ccttaacatt
    70081 ccgaaggcta tacttccaga agttcgttct aactccgaaa tctacggcaa gacagctcca
    70141 ttccatttct acggtggaga ggtgccaatc tcaggtatgg ctggggacca acaagcagcc
    70201 ctctttggac agttggcttt tgagccaggt atggttaaga atacttatgg aacaggctct
    70261 ttcatcatca tgaatactgg ggaagagatg cagttgtctg aaaacaacct cttgacaacc
    70321 attggttacg gaatcaacgg taaggtttat tatgccttgg aaggttctat cttcatcgca
    70381 ggaagtgcta ttcagtggct tcgtgacggt cttcgcatgg ttgaaaattc accagaatct
    70441 gaaaaatacg ctcgtgattc tcacaacaac gatgaagttt atgtcgttcc agcctttaca
    70501 ggtctaggcg ctccatactg gaaccaaaat gctcgtggtt ccgtctttgg tttgactcgt
    70561 ggaacaagca aagaagactt tatcaaggcg actttgcaat ctattgctta tcaagtgcgt
    70621 gacatcatcg acaccatgca agtggatact cagactgcca ttcaagtatt gaaggtggat
    70681 ggtggtgcag ccatgaacaa cttcctcatg cagttccagg cggatatttt aggcattgat
    70741 attgcacgtg ctaaaaactt ggaaacaaca gctctaggag cggccttcct agcaggttta
    70801 tcagtagggt actggaaaga cttggacgag ttgaaactct tgaacgagac aggagaactc
    70861 tttgagccat ctatgaatga atctcgcaag gaacaactct acaagggctg gaagaaggct
    70921 gtgaaagcaa ctcaagtctt tgcggaagta gacgactaat actggcagaa taaagcgatt
    70981 tatttagaaa gtgtgtaaat atggaatttt caaagaaaac acgtgaattg tcaattaaaa
    71041 aaatgcagga acgcaccctg gacctcttga ttatcggtgg aggaatcaca ggagctggtg
    71101 tagccttgca ggcggcagct agcggtcttg agactggttt gattgaaatg caagactttg
    71161 cagaaggaac atctagtcgt tcaacaaaat tggttcacgg aggtcttcgc tacctcaaac
    71221 aattcgacgt agaagtggtc tcagatacgg tttctgaacg tgcagtggtt caacaaatcg
    71281 ctccacacat tccaaaacca gatccaatgc tcttaccagt ttacgatgaa gatggagcaa
    71341 cctttagcct cttccgtctt aaagtagcca tggacttgta cgacctcttg gcaggtgtta
    71401 gcaacacacc aactgcgaac aaggttttga gcaagaaaga agtcttggaa cgccagccaa
    71461 acttgaagaa ggaaggcttg gtaggaggtg gagtgtatct tgacttccgt aacaacgatg
    71521 cgcgtctcgt gattgaaaac atcaaacgtg ccaaccaaga cggtgccctc attgccaacc
    71581 acgtgaaggc agaaggcttc ctctttgacg aaagtggcaa gattacaggt gttgtagctc
    71641 gtgatctctt gacagaccaa gtatttgaaa tcaaggcccg tctggttatt aatacaacag
    71701 gtccttggag tgataaagta cgtaatttgt ctaataaggg aacgcaattc tcacaaatgc
    71761 gcccaactaa gggagttcac ttggtagtgg attcaagcaa aatcaaggtt tcacagccag
    71821 tttacttcga cacaggtttg ggtgacggtc gtatggtctt tgttctccca cgtgaaaaca
    71881 agacttactt tggtacaact gatacagact acacaggtga tttggagcat ccaaaagtaa
    71941 ctcaagaaga tgtagattat ctacttggca ttgtcaacaa ccgctttcca gaatccaaca
    72001 tcaccattga tgatatcgaa agcaactggg caggtcttcg tccattgatt gcagggaaca
    72061 gtgcctctga ctataatggt ggaaataacg gtaccatcag tgatgaaagc tttgacaact
    72121 tgattgcgac tgttgaatct tatctctcca aagaaaaaac acgtgaagat gttgagtctg
    72181 ctgtcagcaa gcttgaaagt agcacatctg agaaatattt ggatccatct gcagtttctc
    72241 gtgggtctag cttggaccgt gatgacaatg gtcttttgac tcttgctggc ggtaaaatca
    72301 cagactaccg taagatggct gaaggagcta tggagcgcgt ggttgacatc ctcaaagcag
    72361 aatttgaccg tagctttaaa ttgatcaatt ctaaaactta ccctgtttca ggtggagaat
    72421 tgaacccagc aaatgtggat tcagaaatcg aagcctttgc gcaacttgga gtatcacgtg
    72481 gtttggatag caaggaagct cactatctgg caaatcttta cggttcaaat gcaccgaaag
    72541 tctttgcact tgctcacagc ttggaacaag cgccaggtct tagcttggca gacaccttgt
    72601 cccttcacta tgcaatgcgc aatgagttga ctcttagccc agttgacttc cttcttcgtc
    72661 gtaccaatca catgctcttt atgcgtgata gcttggatag tatcgttgag ccaattttgg
    72721 atgaaatggg acgattctat gactggacag aagaagaaaa agcaacttac cgtgctgatg
    72781 taaaagcagc tcttgctcaa aacgacttag cagaattaaa aaattaagaa aaaataaaag
    72841 aggtggaggg tagcaatcct tgtcgcccgc ccctttttta atggagacag aaaaatgatg
    72901 agtgaattat ttggagaatt tttagggact ttaatcctga ttcttctagg aaatggtgtt
    72961 gttgcaggtg tggttcttcc aaaaaccaag agcaacagtg caggttggat tgtgattact
    73021 atgggttggg ggattgcagt tgcggttgca gtatttgtat ctggaaaact cagcccagct
    73081 catttaaatc cagctgtgac agttggtgta gctttaaaag gtgacttgcc ttgggcttcc
    73141 gttttgcctt atatcttagc ccagttcgca ggggctatgc tgggtcagat tttggtttgg
    73201 ttgcaattca aacctcacta tgaggcagaa gaaaatgcag gcaatatcct ggcaaccttc
    73261 agtactggac cagccatcaa ggatactgta tcaaacttga ttagcgaaat ccttggaacc
    73321 tttgttttgg tgttgacaat ctttgctttg ggtctttacg attttcaggc aggtatcgga
    73381 acctttgcag tgggaacttt gattgtcggt atcggtctat cactaggtgg gacaacaggt
    73441 tatgccttga acccagctcg tgaccttgga cctcgtatca tgcacagcat cttgccaatt
    73501 ccaaacaagg gagacggaga ctggtcttac gcttggattc ctgttgtagg ccctgttatc
    73561 ggagcagcct tggcagtgct tgtattctca cttttctagt ttatactctt cgaaaatcaa
    73621 attcaaacca cgtcagcgtc gccttaccgt actcaagtac agcttgcggc tagcttccta
    73681 gtttgctctt tgattttcat tgagtattag aaaacaatta tgttgataga gcttgggcaa
    73741 gagcccaatt tcagcaaaaa atgaagtaaa tcttctcata ataaaacgca tcatatcaag
    73801 cacgaaaatt ccacgaggtc aactacagtc agaaagctga acaacaagcc aaaacgccca
    73861 aaaaaggcgg caaaaagcaa gcacctgcaa gcaacgtgcc gaaatggtca aatcctgatt
    73921 atgtcaacga attagaccca aaaatcgttg atatgctagt agaatttcac aagtcacaag
    73981 gcactttgga aactcccgag gcgcaagcag aaatcgccca aaaacgtgaa gaaatcgagc
    74041 aaaggagagc tgagcttgag gataaaaaac aagagctttt gaaccgcttg aacaaataga
    74101 gtttcgcaag tattatgctt acaaattact tgagcaatta actaaaatat aaaccctgcc
    74161 tttatatcta ggcagggttt atattttaga aattcacgta ggttgttacg gtttttacat
    74221 acccagtata gtttgagttt ctatagtatt cagtgataaa cttccatttt ctttgagcaa
    74281 catggatata agtacttgtt atgtagtatg gatatgggct ttgtgaatcc aagtaagact
    74341 gataagcttg tataccaaaa tatgctccac caattattgc accccatgga ccccccaata
    74401 aagcacctat cctaccaatc atataactga ttccagcacc agtcatgaag ttagcgaatg
    74461 tgttagcttg tttattccca tgtattgtgt tgacgtaatt ccaaacatta ggatcgtatg
    74521 atctaaaaga tatatttagg tcgatttcat tcttttgata agccatataa aatgccccat
    74581 tgatatagac gccgtcagca cgtcgttcaa tagtgtctac acttccatct ggattgacaa
    74641 cctcaagaac ttcatcgctt aaaatattta cttgcgtatc tccgaaccgc actgatgagc
    74701 cattctcaaa ctgagcctca ccagatacaa ctttagagtt tgccgataag ctatcatcag
    74761 caaaaacaac aagcgacggg gaaatgctag acatacagaa aacagacata actagcaaac
    74821 acatgcattt aaacatctta gacataacgg aaactccttt gtatttttga tttttttcaa
    74881 cttttattat acaataaaac caaataaaaa gaaagcggta acaatatgct taatgcgaaa
    74941 attttttata tatttttatg tttgatcgtt atcgaaacta caggcttgtt gttgttgaaa
    75001 agaggtctcg aaatgggtta tttagacaca gaagctatta tcctcgcagt tttttcattt
    75061 gctttttaca acctatgttc attcgcttgg gtctgctcta caataaaaaa caataaaaaa
    75121 taaatagacg tattttcaaa aaaaaaaaat gcatatttat cttagcaaaa cgacgattta
    75181 aatcgtcgtt tttttgtagt acgacgggca tgtcgtatat ctgaggtgta agtcctcggt
    75241 gggcacctgc taccggtgaa cccaatagcg attcccaagc ctgactatcg tgaggtagca
    75301 gggagaggaa gggatagcga aatcgtggct ctacgaacag gaacgtgata gtaaggcgta
    75361 tatagcggat aaggaggctt caaactctaa agtccaaaaa ggtagtcgta acctatatgt
    75421 gtaaatcacg agagtaattg aattcggact aaggtttgtg tgaaaaagat aaatctttct
    75481 agagtctaaa gactctgcgt cagatttcct attttcactg taacctttta acgtcctcat
    75541 atcttgtata aacgaggaaa gatgtacgac ttatcccgtg aggtttcatg agcgctgaaa
    75601 gcgtagtaac aacgaatcat gagaagtcag ccgagcccat agtagtgagg aaacttccgt
    75661 aatggaagtg gagcgaaggg gtgaacaact aatcgaagta atcctacttc acttgtgtct
    75721 gtaaaatgag tggtctgata gaactggact ttgacacgta atgactagat gaaggttcac
    75781 caatataaga tgtccctcag gcaccaaaac aagaaaggaa tacgcacatg tcaaaactgc
    75841 tagataagat attatcacgc gaaaatatgc tggaagccta caatcaagta aaatccaata
    75901 aaggctcagc tgggattgat ggaatgacta tcgaagagat ggataattat ctcagacaaa
    75961 actggcgctt gactaaggaa ctgataaaac agagaaaata taagcctcaa ccagttctta
    76021 aagttgagat acctaaacca gacggaggca tccgtcaact aggaattcca acagttatgg
    76081 atagaatgat tcaacaggcc attgtccaag tcatgagccc catttgtgaa ccccatttct
    76141 cagatacgag ttatggtttc agaccaaata ggtcatgtga aaaagccatc atgaagctct
    76201 tagaatactt aaatgacggc tatgagtgga tagtggatat agacctagag aaatttttcg
    76261 atacagttcc tcaagataga ttgatgtcct tagtacataa cattatcgaa gacggagata
    76321 cggaatcctt gattcgtaag tatcttcatt caggtgttat cattaatggt caacgttata
    76381 aaacactagt tggtacacca cagggaggaa atttatctcc tctcttatcc aatatcatgc
    76441 ttaatgaatt ggacaaggaa ttagaaaaga ggggacttcg atttgtgcgc tacgcagatg
    76501 attgtgtgat tacggtcgga agcgaggcag cctctaagcg tgtgatgtat tcagtcagtc
    76561 gttttattga gaaacggcta ggtttgaaag taaacatgac caagactaag attaccagac
    76621 caagagagtt gaaatatcta ggttttgggt tctggaaatc atcagatggt tggaaaagcc
    76681 gtccacatca agatagtgtt cggagattta agtttaaatt gaagaaacta acacagagga
    76741 aatggagtat agacctaaca agacgtattg agcaactgaa tttgtctatt cgaggatgga
    76801 taaactattt ctcattggga aatatgaaaa gtatagtcgc cagcatagat gagcgcttgc
    76861 gtactcgcct acgagtgatt atctggaagc aatggaagaa gaaatcgaga cgattatggg
    76921 gattgcttaa gttaggagtt cctaaatgga tagcagataa ggtatctggc tggggcgacc
    76981 attatcaatt agtagctcag aagtcggtac ttaaacgtgc tatatcaaaa ccagtcct
//
LOCUS       DBEJHE010000008        73814 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC4 isolate 671759
            SAMN38261586-rid24793303.denovo.08, whole genome shotgun sequence.
ACCESSION   DBEJHE010000008 DBEJHE010000000
VERSION     DBEJHE010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261586
            Sequence Read Archive: SRR26833752
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 73814)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 73814)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576136.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576136.1
            Genome Coverage       :: 109x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 19:48:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,067
            CDSs (total)                      :: 2,029
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 131
            CDSs (without protein)            :: 131
            Pseudo Genes (ambiguous residues) :: 0 of 131
            Pseudo Genes (frameshifted)       :: 64 of 131
            Pseudo Genes (incomplete)         :: 59 of 131
            Pseudo Genes (internal stop)      :: 46 of 131
            Pseudo Genes (multiple problems)  :: 32 of 131
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..73814
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261586-rid24793303.denovo.08"
                     /strain="GPSC4"
                     /isolate="671759"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            1..401
                     /locus_tag="ACL3EZ_000696"
                     /pseudo
     CDS             1..401
                     /locus_tag="ACL3EZ_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
     gene            complement(394..561)
                     /locus_tag="ACL3EZ_000697"
     CDS             complement(394..561)
                     /locus_tag="ACL3EZ_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001022221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteinase"
                     /protein_id="HGR0392307.1"
                     /translation="MKKRILSAGLTFTSALLLAACDQSGSDTKTYSSTFSGNPTTFNY
                     LLDYYADNIVN"
     gene            complement(726..2333)
                     /locus_tag="ACL3EZ_000698"
     CDS             complement(726..2333)
                     /locus_tag="ACL3EZ_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HGR0392308.1"
                     /translation="MQEKWWHNAVVYQVYPKSFMDSNGDGVGDLPGITSKLDYLAKLG
                     ITAIWLSPVYDSPMDDNGYDIADYQAIATIFGTMEDMDQLIAEAKKRDIRIIMDLVVN
                     HTSDEHAWFVEACENTDSPERDYYIWRDEPNDLDSIFSGSAWEYDEKSGQYYLHFFSK
                     KQPDLNWENEKLRQKIYEMMNFWIDKGIGGFRMDVIDMIGKIPDEKVVNNGPMLHPYL
                     KEMNQATFGAKDLLTVGETWGATPEIAKLYSDPKGQELSMVFQFEHIGLQYQEGQPKW
                     HYQKELNIAKLKEIFNKWQTELGVEDGWNSLFWNNHDLPRIVSIWGNDQEYREKSAKA
                     FAILLHLMRGTPYIYQGEEIGMTNYPFETLDQVEDIESLNYAREALEKSVPIEEIMDS
                     IRVIGRDNARTPMQWDESKNAGFSTGQPWLAVNPNYEMINVQEALANPDSIFYTYQKL
                     VQIRKENSWLIRADFELLDTADKVFAYIRKDGDRRFLVVANLSNEEQDLTVEGKVKSV
                     LIENTLAQEVFEKQILVPWDAFCVELL"
     gene            2486..3970
                     /locus_tag="ACL3EZ_000699"
     CDS             2486..3970
                     /locus_tag="ACL3EZ_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HGR0392309.1"
                     /translation="MKKQAFSSEQYLNLQRDHILERINQFDGKLYLEFGGKMLEDFHA
                     ARVLPGYEPDNKIKLLQELKEQVEVVIAINASNIEHSKARGDLGISYDQEVLRLIDKF
                     NELGIFVGSVVITQYAGQPAADAFLNQLEKNGIDSYLHYPIKGYPTDMDHIISPEGMG
                     KNDYIKTSRNLIVVTAPGPGSGKLATCMSNMYHDQINGIKSGYAKFETFPVWNLPLHH
                     PVNLAYEAATADLDDINMIDPFHLQTYGETTVNYNRDIEIFPVLKRMLERILGKSPYA
                     SPTDMGVNMVGFAITDDEAAVEASKQEIIRRYYQTVLDFKAEKVGEAAVKKIELLMND
                     LGITPADRKVAVVARQKAEETGGPALAFELPNGEIITGKNSELFGPTAAALINAIKKS
                     ADIAKEVKLIEPEVVKPIQGLKIDHLGSRNPRLHSNEILIALAITATENPDAARAMEE
                     LGNLKGSEAHSTIILTDEDKNVLRKLGINVTFDPYYQYDRLYRK"
     gene            4065..4547
                     /locus_tag="ACL3EZ_000700"
     CDS             4065..4547
                     /locus_tag="ACL3EZ_000700"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HGR0392310.1"
                     /translation="MSKEVIVESFELDHTIVKAPYVRLIGEETGPKGDIISNYDIRLV
                     QPNEDSIPTAGLHTIEHLLAKLIRTRIDGMIDCSPFGCRTGFHMIMWGRHTSAKIAAV
                     IKDSLKEIAETTTWEDVPGTTIESCGNYKDHSLFSAKEWAKLILEQGISDDAFERHVI
                     "
     gene            complement(4843..6948)
                     /locus_tag="ACL3EZ_000701"
     CDS             complement(4843..6948)
                     /locus_tag="ACL3EZ_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001063457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HGR0392311.1"
                     /translation="MNNNFNNFNNMDDLFNQLMGGMRGYSSENRRYLINGREVTPEEF
                     AHYRATGQLPGNAETDVQMPQQASGMKQDGVLAKLGRNLTAEAREGKLDPVIGRNKEI
                     QETSEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGL
                     EAGTQYRGSFEENVQNLVNEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADILKP
                     ALSRGELTVIGATTQDEYRNTILKNAALARRFNEVKVNAPSAENTFKILQGIRDLYQQ
                     HHNVILPDEVLKAAVDYSVQYIPQRSLPDKAIDLVDVTAAHLAAQHPVTDVHAVEREI
                     ETEKDKQEKAVEAEDFEAALNYKTRIAELERKIENHTEDMKVTASVNDVAESVERMTG
                     IPVSQMGASDIERLKDMAHRLQDKVIGQDKAVEAVARAIRRNRAGFDEGNRPIGSFLF
                     VGSTGVGKTELAKQLALDMFGTQDAIIRLDMSEYSDRTAVSKLIGTTAGYVGYDDNSN
                     TLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVIIATS
                     NAGFGYEANLTEDADKPELMDRLKPFFRPELLNRFNAVIEFSHLTKEDLSKIVDLMLA
                     EVNQTLAKKDIDLVVSQAAKDYITEEGYDEVMGVRPLRRVVEQEIRDKVTDFHLDHLD
                     AKHLEADMEDGVLVIREKA"
     gene            complement(7557..8537)
                     /gene="mraY"
                     /locus_tag="ACL3EZ_000702"
     CDS             complement(7557..8537)
                     /gene="mraY"
                     /locus_tag="ACL3EZ_000702"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008963 -
                     phospho-N-acetylmuramoyl-pentapeptide-transferase activity
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HGR0392312.1"
                     /translation="MFISISAGIVTFLLTLVGIPAFIQFYRKAQITGQQMHEDVKQHQ
                     AKAGTPTMGGLVFLITSVLVAFFFALFSSQFSNNMGMILFILVLYGLVGFLDDFLKVF
                     RKINEGLNPKQKLALQLLGGVIFYLFYERGGDMLSVFGYQVHLGIFYIVFALFWLVGF
                     SNAVNLTDGVDGLASISVVISLSAYGVIAYVQGQMDILLVILAMIGGLLSFFIFNHKP
                     AKVFMGDVGSLALGGMLAAISMALHQEWTLLIIGIVYVFETTSVMMQVSYFKLTGGKR
                     IFRMTPVHHHFELGGLSGKGNPWSEWKVDFFFWGVGLLASLLTLAILYLM"
     gene            complement(8539..10791)
                     /gene="pbp2X"
                     /locus_tag="ACL3EZ_000703"
                     /gene_synonym="pbpX"
     CDS             complement(8539..10791)
                     /gene="pbp2X"
                     /locus_tag="ACL3EZ_000703"
                     /gene_synonym="pbpX"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2X"
                     /protein_id="HGR0392313.1"
                     /translation="MKWTKRVIRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNF
                     AVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDE
                     NYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITY
                     ANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENEDGSKSLLGTSG
                     MESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMDGKDVYTTISSPLQSFMETQ
                     MDSFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGITEDFVWRDILYQSNYE
                     PGSTMKVMMLAAAIDNNTFPGGEVFNSSELKIADATIRDWDVNEGLTGGRMMTFSQGF
                     AHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSF
                     GQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQKEIVGNPVSKDAA
                     SLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGGYLVGLT
                     DYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQTTA
                     KALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGKNLAP
                     NQQVLILSDKVEEVPDMYGWTKETAETLAKWLNIELEFQGSGSTVQKQDVRANTAIKD
                     IKKITLTLGD"
     gene            complement(10795..11112)
                     /gene="ftsL"
                     /locus_tag="ACL3EZ_000704"
     CDS             complement(10795..11112)
                     /gene="ftsL"
                     /locus_tag="ACL3EZ_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HGR0392314.1"
                     /translation="MAEKMEKTGQILQMQLKRFSRVEKAFYFSIAVTTLIVAISIIFM
                     QTKLLQVQNDLTKINAQIEEKKTELDDAKQEVNELLRAERLKEIANSHDLQLNNENIR
                     IAE"
     gene            complement(11124..12074)
                     /gene="rsmH"
                     /locus_tag="ACL3EZ_000705"
     CDS             complement(11124..12074)
                     /gene="rsmH"
                     /locus_tag="ACL3EZ_000705"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016434 - rRNA (cytosine)
                     methyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HGR0392315.1"
                     /translation="MTKEFHHVTVLLHETIDMLDVKPDGIYVDATLGGAGHSEYLLSK
                     LSEKGHLYAFDQDQNAIDNAQKRLAPYIEKGMVTFIKDNFRHLQARLREAGVQEIDGI
                     CYDLGVSSPQLDQRERGFSYKKDAPLDMRMNQDASLTAYEVVNNYDYHDLVRIFFKYG
                     EDKFSKQIARKIEQAREVKPIETTTELAEIIKLVKPAKELKKKGHPAKQIFQAIRIEV
                     NDELGAADESIQQAMDMLALDGRISVITFHSLEDRLTKQLFKEASTVEVPKGLPFIPD
                     DLKPKMELVSRKPILPSAEELEANNRSHSAKLRVARKIHK"
     gene            12240..12434
                     /locus_tag="ACL3EZ_000706"
     CDS             12240..12434
                     /locus_tag="ACL3EZ_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGR0392316.1"
                     /translation="MNRVKEFRKELGISQLELAKDIGVSRQTINMIENDKYNPTLELC
                     LNLARSLQTDLNSLFWKEDF"
     gene            12450..12992
                     /locus_tag="ACL3EZ_000707"
     CDS             12450..12992
                     /locus_tag="ACL3EZ_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3278 domain-containing protein"
                     /protein_id="HGR0392317.1"
                     /translation="MKKETFTEKLIKRTYGISGPLDEYKRREADSIGNQVFIVLFYLM
                     IFGNLIPLLLAYKYPQEVALIYPPLILVIALIASGYVTYQMKKTGITVIEPDMLNEKE
                     SKQLHYPGLKAGLFFGLWMFFITPLLRILIGEGQDYFHSLLTIRNGVSSILGSIFFGA
                     SIQFLISRRIAKTKKNQDED"
     gene            13003..13245
                     /locus_tag="ACL3EZ_000708"
     CDS             13003..13245
                     /locus_tag="ACL3EZ_000708"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0392318.1"
                     /translation="MKKEKRQLRYPGLKAGSIYGTVIFFIIPLIDTLTSENPNFISSL
                     LNTKHIFKTILGAFFFGVMIHIVDSLRIARAKKDQD"
     gene            13256..13591
                     /locus_tag="ACL3EZ_000709"
     CDS             13256..13591
                     /locus_tag="ACL3EZ_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0392319.1"
                     /translation="MKSLARLLIIHVFISIFLFFALISGAVSHTVLLLLLLFLPALNK
                     GLEKIQSKRIPVLNAALFFLLISFPQLLTNPVQWKFSIFLVVTIISSLAYFYNFYQVV
                     KEVDQKQLI"
     gene            complement(13701..14702)
                     /locus_tag="ACL3EZ_000710"
     CDS             complement(13701..14702)
                     /locus_tag="ACL3EZ_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGR0392320.1"
                     /translation="MEKKLTIKDIAEMAQTSKTTVSFYLNGKYEKMSQETREKIEKVI
                     HETNYKPSIVARSLNSKRTKLIGVLIGDITNSFSNQIVKGIEDIASQNGYQVMIGNSN
                     YSQESEDRYIESMLLLGVDGFIIQPTSNFRKYSRIIDEKKKKMVFFDSQLYEHRTSWV
                     KTNNYDAVYDMTQSCIEKGYEHFLLITADTSRLSTRIERASGFVDALTDANMRHASLT
                     IEDKHTNLEQIKEFLQKEIDPDEKTLVFIPNCWALPLVFTVIKELNYNLPQVGLIGFD
                     NTEWTCFSSPSVSTLVQPSFEEGQQATKILIDQIEGRNQEERQQVLDCSVNWKESTF"
     gene            complement(14762..16663)
                     /locus_tag="ACL3EZ_000711"
     CDS             complement(14762..16663)
                     /locus_tag="ACL3EZ_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alginate lyase family protein"
                     /protein_id="HGR0392321.1"
                     /translation="MKEERRQFFERIDGNQCRDYILSHCSKDYEKVKSSLERLMDNRF
                     MFDSPWDMEPCSKIHQIQPMVWDQVFEDDPEWAYMLNRQEYLLQFMIGYMVEGDKDYI
                     QKCKFFLFDWIEQVREFSPQSLMTRTLDTGIRSFTWLKLLLLLLKFDLLEEKELEKIL
                     VSLEKQIDFMKSHYRAKYTLSNWGILQTIPMLAIYYFFSDKMDLEEAYHFASEELKQQ
                     IETQILGDGSQFEQSILYHVEVYKALLDLCLLLPDLQDSYRELLEKMATYIQMMTGLD
                     GRTLAFGDSDSTETTEMLSLSAVVLNKEDLLNGLDVKVDLLSLLFLGREKVKRLQEFE
                     KRAWQPKSMIFEDSGHVCIKDEHRYLFFKNGPLGSAHSHSDENSFCLQYQSQPIFIDA
                     GRYSYREIYERYLLKSAWSHSTCIVDGKAPERITGSWEYEYYPHSLFCHHKEREGVHY
                     IEGAYWSAEPDLPYLHKRKILMLVEDVWLLVDDIRCQGQHEALTQFILDKDVTYQDGK
                     INQLRLWSEVDFDLEDTIISPKYNELERSSKLTKRQFFENQMLDYTIIAHESFEIIRH
                     SVYQTDDREVENALAFEVKNDETDKLILLLSEDIGVGEKLCLVDGTKMRGKCLVYDKI
                     NERMIRLQC"
     gene            complement(16685..16978)
                     /gene="yajC"
                     /locus_tag="ACL3EZ_000712"
     CDS             complement(16685..16978)
                     /gene="yajC"
                     /locus_tag="ACL3EZ_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000381741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HGR0392322.1"
                     /translation="MDTTLFYGIVIVLAVSPLLLSSFHSIRQQKLLRKQMEQRQEYLA
                     SLTSGDEVLLLSGIHGKIISIQDDLVSLQIAKGVVLHVEKESVMGKTKELLFK"
     gene            complement(16978..17796)
                     /locus_tag="ACL3EZ_000713"
     CDS             complement(16978..17796)
                     /locus_tag="ACL3EZ_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HGR0392323.1"
                     /translation="MTGSNKLTKRDYLKTSLRAFFCQNGFNYSNYQGLGYANVMYPAL
                     KKHYGEDQEGFYQALEENCEFYNTNPHFLPFITSLHLVMLENGRPTKETRSIKMALMG
                     PLAGIGDSLSQFCLAPLFSTIAASFAQEGLVVGPILFFLAMNTILTAIKLSTGLYGYK
                     LGTTVIDKLSEQMATISRIANIIGVTVIAGLAATSVKIMVPITFAAGEVKADAKQSIV
                     SIQGMLDKVAPALLPALFTLLVYYLIKEKKWTTYKLVILTVIIGIIGSWLKIIA"
     gene            complement(17783..18562)
                     /locus_tag="ACL3EZ_000714"
     CDS             complement(17783..18562)
                     /locus_tag="ACL3EZ_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HGR0392324.1"
                     /translation="MSINVFQAILIGLWTAFCFSGMLLGIYTNRCIVLSFGVGIILGD
                     LPTALAMGAIGELAYMGFGVGAGGTVPPNPIGPGIFGTLMAITSAGKVSPEAALALST
                     PIAVAIQFLQTFAYTVRAGAPETAMKHLKNHNLKKFKFTLNATIWLFAFIGFTLGCLG
                     ALSMDTLLKLVDYIPPVLLTGLTVAGKMLPAIGFAMILSVMAKKELIPFVLLGYVCAA
                     YLNIPTIGIAIVGTIFALIEFYNKPKTADHVVEEEAHDDWI"
     gene            complement(18577..19068)
                     /locus_tag="ACL3EZ_000715"
     CDS             complement(18577..19068)
                     /locus_tag="ACL3EZ_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000178618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGR0392325.1"
                     /translation="MTMPNIIMTRIDERLIHGQGQLWVKYLGCNTVIVANDEVSTDKM
                     QQTLMKTVVPDSVAMRFFPLQKVIAIIHKANPAQTIFIVVKDVKDALTLVEGGVPIKE
                     INIGNIHNATGKEQVTRSIFLGEEDKAALKELSQTHQVTFNTKTTPTGNDGAVQVNIM
                     DYI"
     gene            complement(19079..20269)
                     /locus_tag="ACL3EZ_000716"
     CDS             complement(19079..20269)
                     /locus_tag="ACL3EZ_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003074342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HGR0392326.1"
                     /translation="MIKKVTIEKIKSPERFLEVPLLTKEEVGQAIDKVIRQLELNLDY
                     FKEDFPTPATFDNVYPIMDNTEWTNGFWTGELWLAYEYSQQDAFKNIAHKNVLSFLDR
                     VNKRVELDHHDLGFLYTPSCMAEYKINGDGEAREATLKAADKLIERYQEKGGFIQAWG
                     DLGKKEHYRLIIDCLLNIQLLFFAYQETGDQKYYDIAESHFYASANNVIRDDASSFHT
                     FYFDPETGQPFKGVTRQGYSDDSCWARGQSWGVYGIPLTYRHLKDESCFDLFKGVTNY
                     FLNRLPKDHVSYWDLIFNDGSDQSRDSSATAIAVCGIHEMLKHLPEVDADKDIYKHAM
                     HAMLRSLIEHYANDQFTPGGTSLLHGVYSWHSGKGVDEGNIWGDYYYLEALIRFYKDW
                     NLYW"
     gene            complement(20281..20715)
                     /locus_tag="ACL3EZ_000717"
     CDS             complement(20281..20715)
                     /locus_tag="ACL3EZ_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGR0392327.1"
                     /translation="MKIVLVGHGHFATGIYSSLQLIAGNQENVEAIDFVEGMSADELK
                     QKILLAISNEEEVLILSDLLGGSPFKVSSTIMGENPAKTMNVLSGLNLAMLMEAVFAR
                     MAHSFDEVVNKSVVAAQGGVVNGKELFSTDAEEEEEDFESGI"
     gene            20988..21803
                     /locus_tag="ACL3EZ_000718"
     CDS             20988..21803
                     /locus_tag="ACL3EZ_000718"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HGR0392328.1"
                     /translation="MTNTSFSIEQFSLKGKIALITGASYGIGFAIAKSYAEAGATIVF
                     NDINQDLVNKGIEAYREVGIEAHGYVCDVTDEDGIQAMVKQIEQEVGVIDILVNNAGI
                     IRRVPMCEMSAADFRKVIDIDLNAPFIVSKAVIPSMIKKGHGKIINICSMMSELGRET
                     VSAYAAAKGGLKMLTRNIASEYGGANIQCNGIGPGYIATPQTAPLRELQEDGSRHPFD
                     QFIIAKTPAARWGNPEDLMGPAVFLASDASNFVNGHILYVDGGILAYIGKQPE"
     gene            21822..22463
                     /locus_tag="ACL3EZ_000719"
     CDS             21822..22463
                     /locus_tag="ACL3EZ_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HGR0392329.1"
                     /translation="MKIALINENSQASKNHIIYDSLKEATDKKGYQLFNYGMRGEEGE
                     SQLTYVQNGLMAAILLNTKAVDFVVTGCGTGVGAMLALNSFPGVVCGLAVDPTDAYLY
                     SQINGGNALSIPYAKGFGWGAELTLKLMFERLFAEEMGGGYPRERVIPEQRNARILNE
                     VKQITHNDLMIILKTIDQDFLKDTISGKYFQEYFFENCQDDEVAAYLKEVLAK"
     gene            22494..23495
                     /locus_tag="ACL3EZ_000720"
     CDS             22494..23495
                     /locus_tag="ACL3EZ_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0019200 - carbohydrate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HGR0392330.1"
                     /translation="MTKILLFGEPLIRISPLDATSIGDHVASSTYFGGSEINIACNLQ
                     ALGISTKVFTALPANEIGDRFLTFLKQHQIDTSSICRLGDRIGLYYLENGFGCRQSEV
                     FYDRKHTSISQIRPNMLDMDSLFQGISHFHFSGITVAIGQEVRAILLLLLEEAKRRGI
                     VVSMDLNLRTKMISVLEAKYEFSKFARFTDYCFGIDPLMIDDQNLEMFPRDSASLEEV
                     ENRMRLLKEAYGFKAIFHTLRSSDEQDKNVYQAYALEERFEESVQLKTAVYQRIGSGD
                     AFISGALYQLLHHSSLKTTIDFAVASATLKCTLPGDHLSTSATSIENLLANAQDIIR"
     gene            23505..24134
                     /locus_tag="ACL3EZ_000721"
     CDS             23505..24134
                     /locus_tag="ACL3EZ_000721"
                     /EC_number="4.1.2.14"
                     /EC_number="4.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016829 - lyase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 2-keto-4-hydroxyglutarate
                     aldolase/2-keto-3-deoxy-6-phosphogluconate aldolase"
                     /protein_id="HGR0392331.1"
                     /translation="MTKSDTIIELKKQKIVAVIRGNTKEEGLQASIACIKGGIKAIEI
                     AYTNQYAGQIIKELVDLYQDDQSVCIGAGTVLDAVTARDAILAGANYVVSPSFHAETA
                     KMCNLYSTPYIPGCITLTEITTALEAGSEIIKLFPGSTLSPAYISAVKAPIPQVSVMV
                     TGGVGLNNIPQWFAAGADAVGIGGELNKLASQGNFDRISEIAQQYITLR"
     gene            complement(24278..24340)
                     /locus_tag="ACL3EZ_000722"
                     /pseudo
     CDS             complement(24278..24340)
                     /locus_tag="ACL3EZ_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596946.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(24545..24920)
                     /gene="tnpA"
                     /locus_tag="ACL3EZ_000723"
                     /pseudo
     CDS             complement(24545..24920)
                     /gene="tnpA"
                     /locus_tag="ACL3EZ_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002458050.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(25301..28504)
                     /locus_tag="ACL3EZ_000724"
     CDS             complement(25301..28504)
                     /locus_tag="ACL3EZ_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored hyaluronate lyase"
                     /protein_id="HGR0392332.1"
                     /translation="MQTKTKKLIVSLSSLVLSGFLLNHYMTVGAEETTTNTIQQSQKE
                     VQYQQRDTKNLVENGDFGQTEDGSSSWTGSKAQGWSAWVDQKNSSADASTRVIEAKDG
                     AITISSHEKLRAALHRMVPIEVKKKYKLRFKIKTDNKIGIAKVRIIEESGKDKRLWNS
                     ATTSGTKDWQTIEADYSPTLDVDKIKLELFYETGTGTVSFKDIELVEVAAQLSEDSQT
                     DKQLEEKIDLPIGKKHVFSLADYTYKVENPDLASVKNGILEPLKGGTTNVIVSKDGKE
                     VKKIPLKILASVKDTYTDRLDDWNGIIAGNQHYDSKNEQMAKLNQELEGKVADSLSSI
                     SSQADRTYLWEKFSNYKMSANLTATYRKLEEMAKQVTNPSSRYYQDETVVRTVRDSME
                     WMHKHVYNSEKSIVGNWWDYEIGTPRAINNTLSLMKEYFSDEEIKKYTDVIEKFVPDP
                     EHFRKTTDNPFKALGGNLVDMGRVKVIAGLLRKDDQEISSTIRSIEQVFKLVDQGEGF
                     YQDGSYIDHTNVAYTGAYGNVLIDGLSQLLPVIQKTKNPIDKDKMQTMYHWIDKSFAP
                     LLVNGELMDMSRGRSISRANSEGHVAAVEVLRGIHRIADMSEGETKQRLQSLVKTIVQ
                     SDSYYDVFKNLKTYKDISLMQSLLSDAGVASVPRPSYLSAFNKMDKTAMYNAEKGFGF
                     GLSLFSSRTLNYEHMNKENKRGWYTSDGMFYLYNGDLSHYSDGYWPTVNPYKMPGTTE
                     TDAKRADSDTGKVLPSAFVGTVKLDDANATATMDFTNWNQTLTAHKSWFMLKDKIAFL
                     GSNIQNTSTDTAATTIDQRKLESSNPYKVYVNDKEASLTEQEKDYPETQSVFLESSDS
                     KKNIGYFFFKKSSISMSKALQKGAWKDINEGQSDKEVENEFLTISQAHKQNGDSYGYM
                     LIPNVDRATFNQMIKELESSFIENNETLQSVYDAKQGVWGIVKYDDSVSTISNQFQVL
                     KRGVYTIRKEGNEYKIAYYNPETQESAPDQEVFKKLEQAAQPQVQNSKEKEKSEEEKN
                     HSDQKNLPQTGEGQSILASLGFLLLGAFYLFRRGKNN"
     gene            28727..29203
                     /locus_tag="ACL3EZ_000725"
     CDS             28727..29203
                     /locus_tag="ACL3EZ_000725"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004602 - glutathione peroxidase activity
                     [Evidence IEA];
                     GO_function: GO:0043295 - glutathione binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HGR0392333.1"
                     /translation="MTSLYDFSVLNQNNQATPLDSYRGKVLLIVNTATGCGLTPQYQG
                     LQELYERYQDQGFEILDFPCNQFMGQAPGSAEEINAFCNLHFQTTFPRFAKIKVNGKE
                     ADPLYVWLKDQKSGPLGKRVEWNFAKFLIGRDGQVFERFSSKTDPKQIEEAIQTLL"
     gene            complement(29425..31638)
                     /locus_tag="ACL3EZ_000726"
                     /pseudo
     CDS             complement(29425..31638)
                     /locus_tag="ACL3EZ_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000688702.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TIM-barrel domain-containing protein"
     gene            complement(32040..32216)
                     /locus_tag="ACL3EZ_000727"
     CDS             complement(32040..32216)
                     /locus_tag="ACL3EZ_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0392334.1"
                     /translation="MSLDIDKEKMTIMGIAFENRSVFKSVWYALSTNMIEGWRPTVSD
                     VEKLRDEALALGMT"
     gene            32363..32785
                     /locus_tag="ACL3EZ_000728"
     CDS             32363..32785
                     /locus_tag="ACL3EZ_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGR0392335.1"
                     /translation="MRFIVETFPIFSISNDLLQLLTSWKKQQKYELAKFGIISNPEQF
                     IFTYIDTKGNINKPLHSDYLNNKMKTIRKRHPELTHATPHKLRHTGATLAKQAGMSLE
                     AISEALIHSDTGTTQIYVNTSNVVPMAVGEFALQSLKQ"
     gene            complement(33047..33439)
                     /gene="rpsI"
                     /locus_tag="ACL3EZ_000729"
     CDS             complement(33047..33439)
                     /gene="rpsI"
                     /locus_tag="ACL3EZ_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HGR0392336.1"
                     /translation="MSQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     RLVINQPFAVTSTVGSYDVFVNVVGGGYAGQSGAIRHGIARALLQVDPDFRDSLKRAG
                     LLTRDSRKVERKKPGLKKARKASQFSKR"
     gene            complement(33459..33905)
                     /gene="rplM"
                     /locus_tag="ACL3EZ_000730"
     CDS             complement(33459..33905)
                     /gene="rplM"
                     /locus_tag="ACL3EZ_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HGR0392337.1"
                     /translation="MNKTTFMAKPGQVERKWYVVDATDVPLGRLSAVVASVLRGKNKP
                     TFTPHTDTGDFVIVINAEKVKLTGKKATDKIYYTHSNHPGGLKQISAGELRSKNAVRL
                     IEKSVKGMLPHNTLGRAQGMKLKVFVGAEHTHAAQQPEVLDISGLI"
     gene            34262..34579
                     /locus_tag="ACL3EZ_000731"
     CDS             34262..34579
                     /locus_tag="ACL3EZ_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HGR0392338.1"
                     /translation="MAFTNTHMRSASFGIVTSLPDDIIDSFWYIIDHFLKNVFELEEE
                     LEFQLLNNQGKITFHFSSQHLPTAIDFDFNHPFDPRYPPRVLVLDMDGRETILLPEEN
                     DLF"
     gene            complement(34624..35436)
                     /gene="folK"
                     /locus_tag="ACL3EZ_000732"
     CDS             complement(34624..35436)
                     /gene="folK"
                     /locus_tag="ACL3EZ_000732"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003848 -
                     2-amino-4-hydroxy-6-hydroxymethyldihydropteridine
                     diphosphokinase activity [Evidence IEA];
                     GO_process: GO:0009396 - folic acid-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HGR0392339.1"
                     /translation="MDQLQIKDLEMFAYHGLFPSEKELGQKFVVSAILSYDMTKAATD
                     LDLTASVHYGELCQQWTTWFQETSEDLIETVAYKLVERTFESYPLVQEMKLELKKPWA
                     PVHLSLDTCSVTIHRRKQRAFIALGSNMGDKQANLKQAIDKLRARGIYILKESSVLAT
                     EPWGGVEQDSFANQVVEVETWLPAQDLLETLLAIESELGRVREVHWGPRLIDLDLLFV
                     EDQILYTDDLILPHPYIAERLFVLESLQEIAPHFIHPILKQPIRNLYDALKK"
     gene            complement(35479..36033)
                     /gene="folE"
                     /locus_tag="ACL3EZ_000733"
     CDS             complement(35479..36033)
                     /gene="folE"
                     /locus_tag="ACL3EZ_000733"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003934 - GTP cyclohydrolase I activity
                     [Evidence IEA];
                     GO_process: GO:0046654 - tetrahydrofolate biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HGR0392340.1"
                     /translation="MDTQKIEAAVKMIIEAVGENANREGLQETPARVARMYQEIFSGL
                     GQTAEEHLSKSFEIIDDNMVVEKDIFFHTMCEHHFLPFYGRAHIAYIPDGRVAGLSKL
                     ARTVEVYSKKPQIQERLNIEVADALMDYLGAKGAFVVIEAEHMCMSMRGVRKPGTATL
                     TTVARGLFETDKDLRDQAYRLMGL"
     gene            complement(36014..37336)
                     /locus_tag="ACL3EZ_000734"
     CDS             complement(36014..37336)
                     /locus_tag="ACL3EZ_000734"
                     /EC_number="6.3.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004326 - tetrahydrofolylpolyglutamate
                     synthase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008841 - dihydrofolate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="folylpolyglutamate synthase/dihydrofolate
                     synthase family protein"
                     /protein_id="HGR0392341.1"
                     /translation="MKEIENNQWIANYRTDQPHFGLERMVELLALRGNPHLKLKVLHI
                     GGTNGKGSTIAFLKKMLEKLGLRVGVFSSPYLIHYTDQISINGESISEARLEALMADY
                     QSLLEGEAVANLQGTTEFEIITALAYDYFASEQVDVAIMEVGMGGLLDSTNVCQPILT
                     GITTIGLDHVALLGDTLEAIAEQKAGIIKQGMPLVTGRIAPEALTVIDRIAEGKDAPR
                     LAYGTDYQVRHQESVVTGEVFDYTSAVRQGRFQTSLLGLYQIENAGMAIALLDTFCQE
                     DGRELASNDFLGQALEETSWPGRLEIVSRDPLMILDGAHNPHAIKALLVTLQERFADY
                     HKEILFTCIKTKALGDMLDLLGAMPDTELTLTHFADSRATDESVLKEAAKSRNLSYQD
                     WHDFLEQNLTDKKEEKQTVRIVTGSLYFLSQVRAYLMERKNENGYTKD"
     gene            complement(37338..38312)
                     /gene="folP"
                     /locus_tag="ACL3EZ_000735"
     CDS             complement(37338..38312)
                     /gene="folP"
                     /locus_tag="ACL3EZ_000735"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004156 - dihydropteroate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009396 - folic acid-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HGR0392342.1"
                     /translation="MMKILEGVTDMSSKANHAKTVICGIINVTPDSFSDGGQFFALEQ
                     ALQQARKLIAEGASMLDIGGESTRPGSSYVEIEEEIQRVVPVIKAIRKESDVLISIDT
                     WKSQVAEAALAAGADLVNDITGLMGDEKMAHVVAKAGAKVVIMFNPVMARPQHPSSLI
                     FPHFGFGQTFTEKELADFETLPIEDLMVAFFERALARAAEAGIAPENILLDPGIGFGL
                     TKKENLLLLRDLDKLHQKGYPIFLGVSRKRFVINILEESGFEVNPETELGFRNRDTAS
                     AHVTSIAARQGVEVVRVHDVASHRMAVEIASAIRLADEAENLDLKQYK"
     gene            complement(38407..39114)
                     /locus_tag="ACL3EZ_000736"
     CDS             complement(38407..39114)
                     /locus_tag="ACL3EZ_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysostaphin resistance A-like protein"
                     /protein_id="HGR0392343.1"
                     /translation="MKEKNMWKELLNRAGWILVFLLAVLLYQVPLVVTSILTLKEVAL
                     LQSGLIVTGISIVVLVLFIIGARKTQLASFNFSFFRTKDLARLGLSYLVIICSNILGS
                     ILLQLSNETTTANQSQINDMVQNSSLISSFFLLALLAPICEEILCRGLVPKKIFRGKE
                     NLGFVVGTIVFALLHQPSNLPSLLIYGGMSTVLSWTAYKTQRLEMSILLHMIVNGIAF
                     CLLALVVIMSRTLGISV"
     gene            complement(39167..40585)
                     /locus_tag="ACL3EZ_000737"
     CDS             complement(39167..40585)
                     /locus_tag="ACL3EZ_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HGR0392344.1"
                     /translation="MDKLFKLKENGTDVRTEVLAGLTTFFAMSYILFVNPQILSQTGM
                     PAQGVFLATIIGAVAGTLMMAFYANLPYAQAPGMGLNAFFTFTVVFGLGYSWQEALAM
                     VFICGIISLIITLTNVRKMIIESIPNALRSAISAGIGVFLAYVGIKNAGLLKFTIDPG
                     NYTVVGEGADKAQATIAANSSAVPGLVSFNNPAVLVALAGLAITIFFVIKGIKGGIIL
                     SILTTTVLAIAVGLVDLSSIDFANNHVGAAFEDLKTIFGAALGSEGLGALVSDTARLP
                     ETLMAILAFSLTDIFDTIGTLIGTGEKVGIVATNGENHQSAKLDKALYSDLIGTTVGA
                     IAGTSNVTTYVESAAGIGAGGRTGLTALVVAICFAISSFFSPLLAIVPTAATAPILII
                     VGIMMLGSLKNIYWDDMSEAVPAFFTSIFMGFSYSITQGIAVGFLTYTLTKLVKGQVK
                     DVHAMIWILDALFILNYISMAL"
     gene            40775..41587
                     /locus_tag="ACL3EZ_000738"
     CDS             40775..41587
                     /locus_tag="ACL3EZ_000738"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HGR0392345.1"
                     /translation="MTKKIIAVDLDGTLLNSDSQISDFTKKTIKKVAEKGHQVIITTG
                     RPYRMSKDFYRELGLDTPMINFNGSLTHLPDQVWDFEKCLTVDKKYLLDMVQRSEDIQ
                     ADFIAGEYRKKFYITNPNEEIANPKLFGVEAFQPEDQFQPELVTKDPNCILLQTRASD
                     KYALAKDMNAFYQHQLSINTWGGPLNILECTPKGVNKAFALDYLLKIMNRDKKDLIAF
                     GDEHNDTEMLAFAGKGYAMKNANPELLPYADEQISLTNDQDGVAKTLQDLFL"
     gene            41926..42945
                     /gene="adhP"
                     /locus_tag="ACL3EZ_000739"
     CDS             41926..42945
                     /gene="adhP"
                     /locus_tag="ACL3EZ_000739"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HGR0392346.1"
                     /translation="MKAVVVNPESTGVAIEEKVLRPLETGEALVEVEYCGVCHTDLHV
                     AHGDFGQVPGRVLGHEGIGIVKEIAPDVKSLKVGDRVSVAWFFEGCGTCEYCTTGRET
                     LCRTVKNAGYSVDGGMAEQCIVTADYAVKVPDGLDPAQASSITCAGVTTYKAIKEAKV
                     EPGQWVVLYGAGGLGNLAVQYAKKVFNAHVIAVDINNDKLTLAKEVGADIVINGLEVE
                     DVAGLIKEKTDGGAHSAVVTAVSKVAFNQAVDSIRAGGRVVAVGLPSEMMELSIVKTV
                     LDGIQVIGSLVGTRKDLEEAFQFGAEGLVVPVVQKRPVEDAVAIFDEMEKGQIQGRMV
                     LDFTH"
     gene            43178..44167
                     /locus_tag="ACL3EZ_000740"
     CDS             43178..44167
                     /locus_tag="ACL3EZ_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGR0392347.1"
                     /translation="MSIGIIITSHGEFAAGIHQSGSMIFGEQEKVQVVTFMPNEGPDD
                     LYAKFNNAVAAFDAEDEVLVLADLWSGSPFNQASRVMGENPERKFAIITGLNLPMLIQ
                     AYTERLMDAAAGVEKVAANIIKEAKDGIKALPEELNPVEEVASAAAAPVAQTAIPEGT
                     VIGDGKLKINLARLDTRLLHGQVATAWTPDSKANRIIVASDNVAKDDLRKELIKQAAP
                     GNVKANVVPIQKLIEISKDPRFGETHALILFETPQDALRAIEGGVPIKTLNVGSMAHS
                     TGKTLVNTVLSMDKEDVATFEKMRDLGVEFDVRKVPNDSKKDLFDLINKANVK"
     gene            44195..44998
                     /locus_tag="ACL3EZ_000741"
     CDS             44195..44998
                     /locus_tag="ACL3EZ_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0034219 - carbohydrate transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HGR0392348.1"
                     /translation="MSIISMVLVVVVAFFAGLEGILDQFQFHQPLVACTLIGLVTGHL
                     EAGIILGGSLQMIALGWSNIGAAIAPDAALASVAAAIIMVLGGDFTKTGIGVAQAVAI
                     PLAVAGLFLTMIVRTISVGLVHTADAAAKKGDFGAVERAHFIALLFQGLRIALPAALL
                     LMVPTETVQSILSAMPDWLKDGMAIGGGMVVAVGYAMVINMMATREVWPFFALGFVLA
                     AVSDITLIGFGAIGVAIALIYLHLSKTGGNGGGGAATSNDPIGDILEDY"
     gene            45022..45933
                     /locus_tag="ACL3EZ_000742"
     CDS             45022..45933
                     /locus_tag="ACL3EZ_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HGR0392349.1"
                     /translation="MTEKLQLTKSDRKKVWWRSTFLQGSWNFERMQNLGWAYTLIPAI
                     KKLYTKKEDQIAALERHLEFFNTHPYVAAPVMGVTLALEEERANGVEIDDAAIQGVKI
                     GMMGPLAGIGDPVFWFTVRPILGSLGASLALTGNILGPLLFFVAWNLIRMSFLWYVQE
                     IGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVNIKFAFDVSKVQLDEKA
                     YIHWDKLPEGSKGIQEAFAQVGQGLSQTPEKVTTFQQNLDMLIPGLSGLLLTLLCMYL
                     LKKKVSPITIILALFAVGIVAHVLHIM"
     gene            complement(45989..47323)
                     /gene="pepC"
                     /locus_tag="ACL3EZ_000743"
     CDS             complement(45989..47323)
                     /gene="pepC"
                     /locus_tag="ACL3EZ_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000991632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase C"
                     /protein_id="HGR0392350.1"
                     /translation="MNAIQESFTDKLFANYEANVKYQAIENAASHNGIFAALERRQSH
                     VDNTPVFSLDLTKDKVTNQKASGRCWMFAALNTFRHKLISQYKLENFELSQAHTFFWD
                     KYEKSNWFLEQVIATSDQELTSRKVSFLLQTPQQDGGQWDMVVSLFEKYGVVPKSVYP
                     ESVSSSSSRELNAILNKLLRQDAQILRDLLVSGADQVTVQAKKEDLLQEIFNFLAMSL
                     GLPPRKFDFAYRDKDNNYKSEKGITPQEFYKKYVNLPLEDYVSVINAPTADKPYGKSY
                     TVEMLGNVVGSRAVRYINVPMERLKELAIAQMQAGETVWFGSDVGQLSNRKAGILATD
                     VYDFESSMDIKLTQDKAGRLDYSESLMTHAMVLTGVDLDENGKSTKWKVENSWGDKVG
                     TDGYFVASDAWMDEYTYQIVVRKELLTAEEQAAYGAEPIVLAPWDPMGALAK"
     gene            complement(47501..47734)
                     /gene="blpZ"
                     /locus_tag="ACL3EZ_000744"
     CDS             complement(47501..47734)
                     /gene="blpZ"
                     /locus_tag="ACL3EZ_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000276505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein BlpZ"
                     /protein_id="HGR0392351.1"
                     /translation="MYKHLFFLDSKTLDRLTPYILVLASDTIAFNVFVLTFVSAVVFN
                     FLNSMLALMAIFIGAGYVVGFWLLILNENQRAN"
     gene            complement(47776..48465)
                     /locus_tag="ACL3EZ_000745"
     CDS             complement(47776..48465)
                     /locus_tag="ACL3EZ_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysostaphin resistance A-like protein"
                     /protein_id="HGR0392352.1"
                     /translation="MKKYQLLFKISAVFSYLFFVFGLSQMTLIIQNYWQFSSQIGNFV
                     WIQNFLSLLFSGVMIWILVKTGHGYLFHIPRKKWLWYSILTVLVVVLQISFNVQTAKH
                     VQSTAEGWAVLIGYSGTNFAELGIYITLFFLTPLMEELIYRGLLQHAFFKHSRFGLDL
                     LLPSILFALPHFSSLPSLLDIFIFATSGIIFASLTRYTKSIYPSYAVHVINNIFATLP
                     FLLTFLHRVLG"
     gene            complement(48517..48900)
                     /locus_tag="ACL3EZ_000746"
     CDS             complement(48517..48900)
                     /locus_tag="ACL3EZ_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
                     /protein_id="HGR0392353.1"
                     /translation="MKYRLFFVIFLSSVLDILLGTFLQISIVSIGWLVLYSGLFEAGV
                     FLLANKGVAVKIKEVDIRNRFKFIFGKTLWFQILLLIFLIIKLYLGLDARLILFYGHI
                     FIVFNALMYLLSSSQVSLKKNKLSS"
     gene            complement(49529..49848)
                     /locus_tag="ACL3EZ_000747"
                     /pseudo
     CDS             complement(49529..49848)
                     /locus_tag="ACL3EZ_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001826248.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
     gene            complement(50368..50487)
                     /locus_tag="ACL3EZ_000748"
     CDS             complement(50368..50487)
                     /locus_tag="ACL3EZ_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000346296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PncF family bacteriocin immunity protein"
                     /protein_id="HGR0392354.1"
                     /translation="MDFKSFIIGLVVGIFGPYMDDLIRKIFSKSSKKDTDSTL"
     gene            complement(50591..50740)
                     /gene="blpO"
                     /locus_tag="ACL3EZ_000749"
     CDS             complement(50591..50740)
                     /gene="blpO"
                     /locus_tag="ACL3EZ_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpO"
                     /protein_id="HGR0392355.1"
                     /translation="MNTKMMSQFSVMDNEMLACVEGGDIDWGRKISCAAGVAYGAIDG
                     CATTV"
     gene            complement(50984..51232)
                     /gene="blpK"
                     /locus_tag="ACL3EZ_000750"
     CDS             complement(50984..51232)
                     /gene="blpK"
                     /locus_tag="ACL3EZ_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpK"
                     /protein_id="HGR0392356.1"
                     /translation="MDTKMISQFSVMDNEMLACVEGGGCNWGDFAKAGVGGAAVVAAL
                     GCAAGGVKYGKILGPWGAAIGGIGGAVVCGYLAYTATS"
     gene            complement(51301..51570)
                     /gene="blpJ"
                     /locus_tag="ACL3EZ_000751"
     CDS             complement(51301..51570)
                     /gene="blpJ"
                     /locus_tag="ACL3EZ_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpJ"
                     /protein_id="HGR0392357.1"
                     /translation="MNTKMLSQLEVMDTEMLAKVEGGYSSTDCQNALITGVTTGIITG
                     GTGAGLATLGVAGLAGAFVGAHIGAIGGGLTCLGGMVGDKLGLSW"
     gene            complement(52037..52234)
                     /gene="blpI"
                     /locus_tag="ACL3EZ_000752"
     CDS             complement(52037..52234)
                     /gene="blpI"
                     /locus_tag="ACL3EZ_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpI"
                     /protein_id="HGR0392358.1"
                     /translation="MNTKMMEQFSVMDNEELEIVSGGRGNLGSAIGGCIGAVLLAAAT
                     GPITGGAATLICVGSGIMSSL"
     gene            52516..53103
                     /locus_tag="ACL3EZ_000753"
     CDS             52516..53103
                     /locus_tag="ACL3EZ_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine peptidase family C39 domain-containing
                     protein"
                     /protein_id="HGR0392359.1"
                     /translation="MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKT
                     NKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDVPYPFIVHVNKEGKLQHYYVVYQ
                     TKKDYLIIGDPDPSVKITKMSKERFFYEWTGVAIFLATKPSYQPHKDKKNGLLSKLPS
                     SDFQTKISHCLHCSLKLIGHYYQYRWFLLSPRNLG"
     gene            53030..54673
                     /locus_tag="ACL3EZ_000754"
     CDS             53030..54673
                     /locus_tag="ACL3EZ_000754"
                     /inference="COORDINATES: protein motif:HMM:TIGR01193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0043214 - ABC-type bacteriocin transporter
                     activity [Evidence IEA];
                     GO_process: GO:0043213 - bacteriocin transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HGR0392360.1"
                     /translation="MVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVI
                     TYILQQVMSFSRDYLLTVLSQRLSIDVILSYIRHIFELPMSFFATRRTGEIISRFTDA
                     NSIIDALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLISIPIYMFIIFSFMKPFE
                     KMNHDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYS
                     ILQTSLKQGTKLVLNILILWFGAQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQT
                     KLQSAKVANNRLNEVYLVESEFQVQENPVHSHFLMGDIEFDDLSYKYGFGRDTLTDIN
                     LTIKQGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINHQDIKNIDKKVLRRHINY
                     LPQQAYIFNGSILENLTLGGNHMISQEDILRACELAEIRQDIERMPMGYQTQLSDGAG
                     LSGGQKQRIALARALLTKAPVLILDEATSGLDVLTEKKVIDNLMSLTDKTILFVAHRL
                     SIAERTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK"
     gene            54684..56045
                     /locus_tag="ACL3EZ_000755"
     CDS             54684..56045
                     /locus_tag="ACL3EZ_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
                     /protein_id="HGR0392361.1"
                     /translation="MNPNLFRSVEFYQRRYHNYATVFIIPLSLLFTFILIFSLVATKE
                     ITVTSQGEIAPTSVIASIQSTSDNPILANHLVANQVVEKGDLLIKYSETMEESQKTAL
                     ATQLQRLEKQKEGLGILKQSLEKATDLFSGEDEFGYHNTFMNFTKQSHDIELGITKTN
                     TEVSNQANLSNSSSSAIEQEITKVQQQIGEYQELRDAIINNRARLPTGNPHQSILNRY
                     LVASQGQTQGTAEEPFLSQINQSIAGLESSIASLKIQQAGIGSVATYDNSLATKIEVL
                     RTQFLQTASQQQLTVENQLTELKVQLDQATQRLENNTLTSPSKGIVHLNSEFEGKNRI
                     PTGTEIAQIFPVITDTREVLITYYVSSDYLPLLDKGQTVRLKLEKIGNHGTTIIGQLQ
                     TIDQTPTRTEQGNLFKLTALAKLSNEDSKLIQYGLQGRVTSVTTKKTYFDYFKDKILT
                     HSD"
     gene            56102..56230
                     /gene="blpC"
                     /locus_tag="ACL3EZ_000756"
     CDS             56102..56230
                     /gene="blpC"
                     /locus_tag="ACL3EZ_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system pheromone BlpC"
                     /protein_id="HGR0392362.1"
                     /translation="MDKKQNLTSFQELTTTELNQITGGGLWEDLLYNINRYAHYIT"
     gene            complement(56301..57641)
                     /locus_tag="ACL3EZ_000757"
     CDS             complement(56301..57641)
                     /locus_tag="ACL3EZ_000757"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HGR0392363.1"
                     /translation="MNIAWILLYTLVTNGLEIVIFFKVDGIDLTFERIFKAFLFKILL
                     AFVFVMISYIVGNVYLSYFMEPLYGIGLSFLLLRGLPKKLLFFYGLFPMILVNLFYRG
                     VSYFVLPFLGQGQVYDGYSFTGLCIIIFNFFISLAFLKWLDYDFTSLRKEILDKAFQK
                     SLTQINWIMGGYYLVMESLSFFEYEQSIQSKTVRHLILVFYLLFFMGVIKKLDTYLKE
                     KLYERLEQEQALRYRDMERYSRHIEELYKEVRSFRHDYTNLLTSLRLGIEEEDMEQIK
                     EVYGSVLKDSSQKLQNNKYDLGRLVNIRDKALKSLLAGKFLKARDKNIVFNVEVPEEI
                     QVEGMSLLDFLTIVSILCDNAIEASVEASQPHVSIAFLKNGAQETFIIENSIKEEGID
                     ISEIFSFGASSKGEERGVGLYTVMKIVESHPNTSLNTTCQNQVFRQVLTVIHTE"
     gene            complement(57655..58347)
                     /locus_tag="ACL3EZ_000758"
     CDS             complement(57655..58347)
                     /locus_tag="ACL3EZ_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001219140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGR0392364.1"
                     /translation="METTIEKLLKAHHIIPSSFEVFGKPDQLLAEVHEKGAHQLFFLD
                     IEIRNEEMKGLEVARKIRDRDPYALIVFVTTHSEFMPLSFRYQVSALDYIDKALSAEE
                     FESRIETALLYANSQDSKSLAEDCFYFKSKFAQFQYPFKEVYYLETSPRAHRVILYTK
                     TDRLEFTASLEEVFKQEPRLLQCHRSFLINPANVVHLDKKEKLLFFPNGGSCLIARYK
                     VREVSEAINKLH"
     gene            complement(58397..58735)
                     /locus_tag="ACL3EZ_000759"
     CDS             complement(58397..58735)
                     /locus_tag="ACL3EZ_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family DNA-binding domain-containing
                     protein"
                     /protein_id="HGR0392365.1"
                     /translation="MKYMIIQTQKTVYKVNIDDIYYIQTHPTKAHTVQIVTEEASFNM
                     LQNLSNLENQCGETLMRCHRNCLVNLDKLKSIDFQERILFLGEEGQYAVKYARRRYRE
                     IRQKWLKEGE"
     gene            59011..59340
                     /locus_tag="ACL3EZ_000760"
     CDS             59011..59340
                     /locus_tag="ACL3EZ_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HGR0392366.1"
                     /translation="MTDTDPIKRAHTLITDLNKAYQACKQASADDVRFQEQLNSILGF
                     LAKAETVDNRFLIELEKFYQTSSLLMGLSALDPDAPTRAAWRAYDRFHFDQVKTKLIL
                     NENQRAN"
     gene            complement(59508..60557)
                     /locus_tag="ACL3EZ_000761"
     CDS             complement(59508..60557)
                     /locus_tag="ACL3EZ_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0392367.1"
                     /translation="MKDLFLKRKQAFRKECLGYLRYVLNDHFVLFLLVLLGFLAYQYS
                     QLLQHFPENHWPILLFVGITSVLLLLWGGIATYMEAPDKLFLLVGEEEIKLHLKRQTG
                     ISLVFWLFVQTLFLLLFAPLFLAMGYGLPVFLLYVLLLGVGKYFHFRQKASKFFTETG
                     LDWDYVISQESKRKQVLLRFFALFTQVKGISNSVKRRAYLDFILKAVQKVPGKIWQNL
                     YLRSYLRNGDLFALSLRLLLLSVLAQVFIEQAWIATAVVVLFNYLLLFQLLALYHAFD
                     YQYLTQLFPLDKGQKEKGLQEVVRGLTSFVLLVELVVGLITFQEKLALLALLGAGLVL
                     LVLYLPYQVKRQMQD"
     gene            complement(60554..61285)
                     /locus_tag="ACL3EZ_000762"
     CDS             complement(60554..61285)
                     /locus_tag="ACL3EZ_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0392368.1"
                     /translation="MLEIKNLTGGYVHVPVLKDVSFTVESGQLVGLIGLNGAGKSTTI
                     NEIIGLLAPYSGSININGLTLQGDATSYRKQIGYIPETPSLYEELTLREHIETVAMAY
                     GIEQKVAFERVEPLLKMFRLEQKLDWFPVHFSKGMKQKVMIICAFVADPSLFIVDEPF
                     LGLDPLAISDLIQLLEVEKQKGKSILMSTHVLDSAEKMCDAFVILHKGEVRAKGNLLQ
                     LREAFDMPEASLNDIYLALTKEEDL"
     gene            61353..61763
                     /locus_tag="ACL3EZ_000763"
     CDS             61353..61763
                     /locus_tag="ACL3EZ_000763"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HGR0392369.1"
                     /translation="MSDCIFCKIIAGEIPASKVYEDEQVLAFLDISQVTLGHTLVVPK
                     EHYRNLLEMDATSASQLFAQVPKVAQKVMKVTKAAGMNIISNCEEVAGQTVFHTHVHL
                     VPRYSADDDLKIDFIAHEPDFDKLAQVAETIKNA"
     gene            61773..62060
                     /locus_tag="ACL3EZ_000764"
     CDS             61773..62060
                     /locus_tag="ACL3EZ_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0392370.1"
                     /translation="MKLSNLLLFAGAAAGSYLVTKNRQTITDEVLNTTDRVQAIKDDV
                     DIIQNSLQIIDQQKELIKEYQEDLTYKFKVLEKDIQTRLAVIKEMQGTEDK"
     gene            complement(62750..63886)
                     /gene="dnaJ"
                     /locus_tag="ACL3EZ_000765"
     CDS             complement(62750..63886)
                     /gene="dnaJ"
                     /locus_tag="ACL3EZ_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HGR0392371.1"
                     /translation="MNNTEFYDRLGVSKNASADEIKKAYRKLSKKYHPDINKEPGAED
                     KYKEVQEAYETLSDDQKRAAYDQYGAAGANGGFGGAGGFGGFNGAGGFGGFEDIFSSF
                     FGGGGSSRNPNAPRQGDDLQYRVNLTFEEAIFGTEKEVKYHREAGCRTCNGSGAKPGT
                     SPVTCGRCHGAGVINVDTQTPLGMMRRQVTCDVCHGRGKEIKYPCTTCHGTGHEKQAH
                     SVHVKIPAGVETGQQIRLAGQGEAGFNGGPYGDLYVVVSVEASDKFEREGTTIFYNLN
                     LNFVQAALGDTVDIPTVHGDVELVIPEGTQTGKKFRLRSKGAPSLRGGAVGDQYVTVN
                     VVTPTGLNDRQKVALKEFAAAGDLKVNPKKKGFFDHIKDAFDGE"
     gene            complement(64288..64644)
                     /locus_tag="ACL3EZ_000766"
     CDS             complement(64288..64644)
                     /locus_tag="ACL3EZ_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanine-N7)-methyltransferase"
                     /protein_id="HGR0392372.1"
                     /translation="MSVLDDEYLKNTRKVYNDFCNQADNYEAAKGFIDNIPVECLTIY
                     REIILAEHDSCVKNDEAVRNFVTSVLLSAFVSAMVSAMISLEIQTYKFVIPFIIGMIW
                     TVVVFLMINWNYIGKY"
     gene            complement(64646..66469)
                     /gene="dnaK"
                     /locus_tag="ACL3EZ_000767"
     CDS             complement(64646..66469)
                     /gene="dnaK"
                     /locus_tag="ACL3EZ_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HGR0392373.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKN
                     GEIIVGDAAKRQAVTNPDTVISIKSKMGTSEKVSANGKEYTPQEISAMILQYLKGYAE
                     DYLGEKVTKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTDK
                     EEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNKLGGDDFDQKIIDHLVAEFKKEN
                     GIDLSTDKMAMQRLKDAAEKAKKDLSGVTSTQISLPFITAGEAGPLHLEMTLTRAKFD
                     DLTRDLVERTKVPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKS
                     VNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSK
                     SQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDK
                     NGIVSVKAKDLGTQKEQTIVIQSNSGLTDEEIDRMMKDAEANAEADKKRKEEVDLRNE
                     VDQAIFATEKTIKETEGKGFDAERDAAQAALDDLKKAQEDNNLDDMKAKLEALNEKAQ
                     GLAVKLYEQAAAAQQAQEGAEGAQATGNAGDDVVDGEFTEK"
     gene            complement(66949..67473)
                     /gene="grpE"
                     /locus_tag="ACL3EZ_000768"
     CDS             complement(66949..67473)
                     /gene="grpE"
                     /locus_tag="ACL3EZ_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000046028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HGR0392374.1"
                     /translation="MAQDIKNEEVEEVQEEEVVETAEETTPEKSELDLANERADEFEN
                     KYLRAHAEMQNIQRRANEERQNLQRYRSQDLAKAILPSLDNLERALAVEGLTDDVKKG
                     LAMVQESLIHALKEEGIEEIAADGEFDHNYHMAIQTLPADDEHPVDTIAQVFQKGYKL
                     HDRILRPAMVVVYN"
     gene            complement(67500..68534)
                     /gene="hrcA"
                     /locus_tag="ACL3EZ_000769"
     CDS             complement(67500..68534)
                     /gene="hrcA"
                     /locus_tag="ACL3EZ_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HGR0392375.1"
                     /translation="MVTERQQDILNLIIDIFTKTHEPVGSKTLQESINSSSATIRNDM
                     AELEKQGLLEKAHTSSGRMPSVAGFQYYVKHSLDFDRLAENEVYEIVKAFDQEFFKLE
                     DILQEAANLLTDLSGCTVVALDVEPSRQRLTAFDIVVLGQHTALAVFTLDESRTVTSQ
                     FLIPRNFLQEDLLKLKSIIQERFLGHTVLDIHYKIRTEIPQIIQRYFTTTDNVIDLFE
                     HIFKEMFNENIVMAGKVHLLNFANLAAYQFFDQPQKVALEIREGLREDQMQNVRVADG
                     QESCLADLAVISSKFLIPYRGVGILAIIGPVNLDYQQLINQVNVVNRVLTMKLTDFYR
                     YLSSNHYEVH"
     gene            complement(68698..69208)
                     /locus_tag="ACL3EZ_000770"
                     /pseudo
     CDS             complement(68698..69208)
                     /locus_tag="ACL3EZ_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001088691.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
     gene            69816..72149
                     /gene="hsdR"
                     /locus_tag="ACL3EZ_000771"
     CDS             69816..72149
                     /gene="hsdR"
                     /locus_tag="ACL3EZ_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0015666 - restriction
                     endodeoxyribonuclease activity [Evidence IEA];
                     GO_process: GO:0009307 - DNA restriction-modification
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="EcoAI/FtnUII family type I restriction enzme
                     subunit R"
                     /protein_id="HGR0392376.1"
                     /translation="MVEFIKSKKEMSEEDIKANFITPAIVSKGWKNGEHIAYEEYFTD
                     GRIEVRGDKARRKEGKKSDYSLYYQFGTRIAIVEAKDNKHSVRAGLQQAIEYGEILDV
                     PFVYSSNGDGFIEHDRITREERELELDEFPTREELFSRMTKEKGLTYEITEAISTPYY
                     TDAFSMKTPRYYQQIAINRTIETVARGQKRVMFVMATGTGKTFMAFQIIHRLRKAGLA
                     KRVLFLADRNILVDQTMAEDFRPFEKVMTKITPKLLTAPEKLNSFEIYLGLYQQLTGE
                     DGTETHYQKFDKDFFDLIVIDEAHRGSAKENSNWRKVIDYFSSATQIGMTATPKETKN
                     ASNTEYFGEPIYTYSLKQGIEDGFLAPYRVMRVNLDVDVDGYRPETGKVDANGQLIED
                     RYYGRKDFDKTIVIDDRTQRVAKFVSDYMKQNNARFDKTIVFCVDIDHAERMRAALVK
                     ENLALVQEDYRYVMQVTGDNAEGKAQLDNFMDVNSNFPAIVTTSKLLTTGVNAKTCRL
                     IVLDSNIQSMTEFKQIIGRGTRLYPQKGKEFFTIIDFRNVTNLFADPDFDGDPVKVLE
                     TGAKTVSGSTPGFVDEEGDPVEKYIVTDKQVTILNSTVQVLDENGKLITESLTDYTRK
                     NILGSYATLNDFITVWHTADKKKLILDELYKKGVYLDAIRESEGISEQEIDDFDLLLK
                     LAYGQKELTKTERINKLKQSGYLYKYSEEARAVLEILLNKYMDKGIGELESIETLKLP
                     EFQIYGGTFKIINTYFGDKKRYLQAIKELEQELFTVA"
     gene            72162..73625
                     /locus_tag="ACL3EZ_000772"
     CDS             72162..73625
                     /locus_tag="ACL3EZ_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008170 - N-methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-6 DNA methylase"
                     /protein_id="HGR0392377.1"
                     /translation="MSITSFVKRIQDITRNDAGVNGDAQRIEQMSWLLFLKIYDSREM
                     VWELEEDEYESIIPEELKWRNWAHAQNGERVLTGDELLDFVNNKLFKELKELEITSIM
                     PIRKTIVKSAFEDANNYMKNGVLLRQVINVIDEVDFNSPEDRHSFNDIYEKILKDIQN
                     AGNSGEFYTPRAATDFIAEVLNPKLGESMADLACGTGGFLTSTLNRLSSQRKTSEDTK
                     KYNTAVFGIEKKAFPHLLAVTNLFLHEIDDPKIVHGNTLEKNVREYTDDEKFDIIMMN
                     PPFGGSELETIKNNFPAELRSSETADLFMAVIMYRLKENGRVGVILPDGFLFGEGVKT
                     RLKQKLVDEFNLHTIIRLPHSVFAPYTGIHTNILFFDKTKKTEETWFYRLDMPDGYKN
                     FSKTKPMKSEHFNPVRDWWENREEILEGKFYKSKSFTPSELAELNYNLDQCGFPKEEE
                     EILNPFELIQNYQAERATLNHKIDNVLADILQLLEDK"
     gene            73625..>73814
                     /locus_tag="ACL3EZ_000773"
     CDS             73625..>73814
                     /locus_tag="ACL3EZ_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease"
                     /protein_id="HGR0392378.1"
                     /translation="MTPEQLKASILQRAMEGKLVPQNPNDEPASELLKRIKAEKEKLI
                     SEGKIKRDKKETEIFRGDD"
BASE COUNT        22497 a        15861 c        13357 g        22099 t
ORIGIN      
        1 attaaaaggt cagttaataa gaggtaaagt atctggaaga agatatcaga ggatttcttt
       61 gattgcaggt ctaacaaatg aatggtgagt taatcgctcc aatgacttac gaagagacga
      121 tgacgagcga cttttttgaa gcttggtttc agaaatttct cttaccaaca ttaaccacac
      181 catcggttat tattatggat aatgcaagat tccatagaat ggggaagcta gaacttttat
      241 gcgaagagtt tgggcataaa cttttacctc ttcctcccta ctcacctgag tacaatccta
      301 ttgagaaaac atgggctcat atcaaaaagc acctcaaaaa ggtattacca agttgcaata
      361 ccttttatga ggctcttttg tcttgttctt gtttcaattg actatattat cagcgtaata
      421 gtctaataga tagttaaatg tagttggatt tccactaaag gttgatgagt aagtttttgt
      481 atctgaacct gattggtcgc aagcagctaa aagcaaagca gatgtaaaag tcaggcctgc
      541 actaaggata cgcttcttta tgttcgtctt ctttctcctt aatagtggga atttgtaaag
      601 ttaattgaat ttcgagaatg aaggtttata aaccttggtt ataaaaaaca aaggatttct
      661 gccttttata cagtcctccc ttgtttttat acgatttcaa ttttaaattt ttctgcaaaa
      721 aatatttata gtaattccac acagaaagca tcccatggaa ctaagatttg tttttcaaag
      781 acttcttgag ctagggtgtt ttcaatcaag acagatttga cttttccttc tactgtcaag
      841 tcttgctctt cattggacaa gttagccaca actaggaagc gacggtcgcc atccttacgt
      901 atataagcaa agaccttatc agccgtatca agcaattcaa agtcagctcg aattagccag
      961 ctattctcct tgcgaatttg gaccagtttc tgataggtat agaaaataga atctggattt
     1021 gccagcgctt cttggacatt gatcatctcg taatttggat taaccgccaa ccaaggttga
     1081 cctgttgaga aaccagcgtt tttgctctcg tcccattgca taggggtacg ggcattgtca
     1141 cgtccaataa cacggatact gtccatgatt tcttcaatcg gaacactttt ttcaagagcc
     1201 tcacgcgcat agttgaggga ttcaatatct tctacttgat ccagtgtttc aaacggatag
     1261 ttggtcatcc caatctcctc accttggtag atataaggag ttcctctcat gagatgaagt
     1321 aagattgcaa aggctttggc agatttttcg cggtattctt ggtcatttcc ccagattgag
     1381 acaatacgag ggaggtcatg gttgttccag aagagggaat tccagccgtc ctcaactcct
     1441 aactctgtct gccatttgtt gaagatttct tttaacttag cgatattcag ctctttttga
     1501 tagtgccatt taggttgacc ttcctgatac tgaagaccga tatgttcaaa ctggaagacc
     1561 atagacaatt cttgcccctt tggatcagag tagagcttgg caatctctgg cgttgctccc
     1621 caagtctccc ctactgtcaa gagatcctta gctccaaagg tcgcctgatt catttccttg
     1681 agatagggat ggagcatagg accattattg actaccttct cgtcaggaat tttgccaatc
     1741 atgtcaataa catccatacg gaaaccacca atacctttat caatccagaa gttcatcatc
     1801 tcataaattt tctggcgaag tttttcattt tcccagttga gatccggctg tttcttgctg
     1861 aaaaagtgga gatagtattg acctgacttt tcatcgtatt cccaagcaga cccactaaag
     1921 atagaatcta ggtcattggg ttcatcgcgc cagatatagt agtctcgctc agggctatca
     1981 gtattttcac aggcttcgac aaaccaagca tgttcatctg aggtatgatt aaccaccaag
     2041 tccatgatga tacgaatgtc acgcttctta gcttccgcaa tcagttgatc catatcctcc
     2101 atggttccaa aaatcgttgc aatcgcttga taatcagcaa tatcgtagcc attatcatcc
     2161 atagggctgt cataaacggg agaaagccaa atcgctgtga ttcctaactt agctagatag
     2221 tccaacttac tggtaatacc tggcaaatca ccaactccat ctccattact atccataaaa
     2281 ctctttggat agacttgata gactacggca ttatgccacc atttttcttg catctgttta
     2341 cctcattatt ttcataatct atagtatatg ataacacttt ttaaaatttt gtgcaagcgt
     2401 ttgcttaatc tttttaattt cttttttagc tccgtagttt cctaacttcc aattttttat
     2461 tataatagag gtcagaggta aaaaaatgaa aaaacaagct tttagttctg aacaatattt
     2521 gaatttacaa cgcgaccata ttttggaacg cattaaccaa tttgacggca agctctactt
     2581 agagtttggc ggtaaaatgt tagaagattt ccacgctgct cgtgtccttc ctggttatga
     2641 acctgacaac aaaatcaagc tcttgcaaga attgaaagag caggttgagg ttgtgattgc
     2701 cattaatgct agcaacattg aacattccaa agcacgtggc gacttgggca tttcttatga
     2761 ccaagaagtt cttcgtttga ttgacaaatt caatgaatta gggatttttg ttggttccgt
     2821 tgtcattaca caatacgctg gccaacccgc tgcagatgcc ttcctcaacc aacttgagaa
     2881 aaacggaatt gattcttatc ttcattatcc aatcaaagga tatccgacgg atatggatca
     2941 catcatttcc ccagaaggca tgggcaaaaa cgactacatc aaaaccagtc gcaacttgat
     3001 tgtcgtaacc gctcctggac ctggttctgg aaaattggca acgtgtatgt ccaatatgta
     3061 ccacgaccaa atcaatggca tcaagtctgg ctacgctaaa tttgaaacct tccctgtttg
     3121 gaatcttccc cttcatcatc cagttaactt ggcttatgaa gctgccacag ctgaccttga
     3181 tgatatcaac atgattgacc ccttccatct tcaaacctat ggagaaacca ctgtcaacta
     3241 caaccgtgat atcgaaatct tcccagtgct caagcgcatg ttggaacgta ttctcggaaa
     3301 atcaccatac gcttcaccga cagatatggg tgtcaacatg gttggtttcg ctattacaga
     3361 tgacgaggct gctgtcgaag cttctaaaca agaaatcatc cgccgttact atcaaacagt
     3421 tcttgacttc aaagctgaaa aagttggcga agctgccgtc aagaaaattg agttgctcat
     3481 gaacgacctc ggtatcacac ctgcagaccg taaggttgct gtcgttgcgc gccaaaaagc
     3541 agaagaaact ggtggaccag ccctagcctt tgaattgcca aatggggaaa tcatcactgg
     3601 taagaactca gaactctttg ggcctacagc cgctgccttg atcaacgcca tcaaaaaatc
     3661 agctgacatc gctaaagaag taaaactaat cgagcctgaa gttgttaagc caatccaagg
     3721 tcttaaaatc gatcatctcg gtagccgcaa tccacgcctt cattcaaatg aaatcctgat
     3781 tgcacttgct atcacagcta cagaaaatcc tgatgctgcc cgcgctatgg aagaactcgg
     3841 caacctcaaa ggaagcgaag cccactcaac catcatcttg actgatgaag acaaaaatgt
     3901 ccttcgtaaa ctgggtatca acgtaacctt tgacccatac taccaatacg accgcttata
     3961 tcgtaagtaa agatttcaac ctctccagcc tcggagaggt tttctctctg tctcaggagc
     4021 aacctttatg atataatgag agaagaaaac tgaaaggatt taccatgtca aaagaagtta
     4081 ttgtcgaaag ttttgaactt gaccacacca ttgtcaaagc accctatgtt cgcttgattg
     4141 gggaagaaac aggaccaaaa ggagacatca tctccaatta tgatattcgc ttggtgcaac
     4201 caaacgaaga ctccatccct accgccggcc ttcacactat cgagcacctc ttagccaaac
     4261 tcatccgtac ccgcattgac ggcatgattg actgttcacc atttggttgc cgcacaggct
     4321 tccacatgat tatgtgggga cgtcacacca gtgctaaaat cgcagctgtt atcaaggatt
     4381 cgctcaagga aatcgctgaa actactactt gggaagatgt cccagggaca accatcgaat
     4441 cttgcggaaa ctacaaggac cacagcctct tctctgctaa agaatgggca aaactcatct
     4501 tggaacaagg gatttcagat gatgcctttg aacgtcatgt gatttaaaat cgagtagggg
     4561 ataatctcta gcccctctca caccaccgta cgtgccgttc ggcatacggc ggttcaacta
     4621 acttttaaag catttcgttc taagtagtaa tccaagcatg aaaccagtcc tcgtttgatg
     4681 aggattggtt ttgatatagc tcgtttgaga actgacttct gagctactat agtggattga
     4741 aactagaata gttcacttct actacacgac atgcccgtcg tacctcaaaa ggaaccagtt
     4801 tttttcagct ggctccttct tttttatcct caaaattcta tcttaggctt tctcacgaat
     4861 aaccaaaacg ccatcttcca tatctgcttc cagatgttta gcatctaaat gatccaagtg
     4921 gaagtctgtc accttatcac gaatttcttg ttcaaccact cgacggagag gacgaacccc
     4981 catgacttcg tcgtaacctt cttctgtgat ataatcttta gccgcttgac tgactaccaa
     5041 gtcaatgtct ttcttagcca aggtttggtt aacttcagcc aacatcaaat ctacaatctt
     5101 agaaaggtct tccttagtca agtgtgagaa ctcgatgact gcattaaagc ggttgaggag
     5161 ttctggacgg aagaagggtt tcaaacggtc catcaattct ggtttatccg catcttctgt
     5221 caagttggct tcatagccaa atccagcatt tgaggtcgca ataatgacag tgttcttgaa
     5281 atttactgta tttccttgac catctgtcaa acgaccatca tctagaactt ggaggagaag
     5341 ggtaataact tgaggatcag ccttttcaat ttcatccaag agaatgatag agtatggatt
     5401 gcgacgaaca cgttctgtta aggtattgct attgtcatca taacccacat agcctgctgt
     5461 tgtaccaatt agcttagaaa cagctgtgcg gtcactgtat tcagacatat ccaaacggat
     5521 aatcgcatcc tgggttccaa acatatcgag tgccaattgc ttagcaagct ccgtcttacc
     5581 aaccccagta gaccctacaa agaggaagct gccgattggg cgatttcctt catcaaaacc
     5641 agcacggtta cgacggatag cacgagctac agcttctacg gccttatctt gaccaatcac
     5701 cttgtcttgc aagcgatgag ccatatcttt caaacgttcg atatctgaag ctcccatttg
     5761 cgatactggg atacctgtca ttcgttccac agattcagcc acatcgttga cacttgcagt
     5821 cactttcata tcttctgtgt ggttttcgat tttcctttcc aattctgcaa tgcgtgtttt
     5881 atagtttaga gctgcttcaa aatcttctgc ttcaactgct ttttcttgct tgtctttttc
     5941 cgtttcgatt tctcgttcaa cagcatgcac atctgttact ggatgttgag ccgccaagtg
     6001 agcagccgtt acatcgacaa ggtcaatagc cttatctggc aagctacgtt gaggaatgta
     6061 ttgaacagaa taatccaccg ctgctttcaa gacttcgtct ggcaagatga cattgtggtg
     6121 ttgttgatag agatcacgaa tgccttgaag aattttaaaa gtattctctg ctgaaggagc
     6181 attgaccttc acttcgttga aacgacgagc aagagcagca ttcttcaaga tggtgttacg
     6241 gtattcgtct tgagttgttg ccccaatcac tgtcaattct ccacgagaga gagctggctt
     6301 gagaatatcc gcaagtcctt tagaaccact gtctccacca gtgctaccag caccaagaat
     6361 ttggtgaatt tcatcaaaga agaggataat attccctgct tctttcactt cattgactaa
     6421 gttttggaca ttttcttcaa agctaccacg gtattgagta ccagcctcaa gacctgagat
     6481 atcaatagaa ataatttcct tgttcttgat agcagcagga acatctccgt tcacaatggc
     6541 ttgcgctaga ccttcgacaa ctgctgtctt accaacacct gcatctccga ccaaaacagg
     6601 attgttcttg gtgcggcgtg agaggatttc agatgtttct tgaatttcct tgtttcgtcc
     6661 gataacagga tccaacttgc cctcacgcgc ttctgctgtc aagtttcgac ctagttttgc
     6721 aaggacaccg tcttgtttca tacctgatgc ctgttgtggc atttgcacat cagtttctgc
     6781 atttcctggt aattgaccag tcgcacgata gtgagcaaat tcctcaggtg tgacttcgcg
     6841 tccattaatt aagtaacggc gattttcaga actatatcct cgcataccac ccatcaattg
     6901 gttaaataaa tcatccatgt tattaaaatt attaaagttg ttattcatat tctttacctc
     6961 tttttgttta cttagttatg attactgata ttgactatct ttgaccattg ttttaaaaaa
     7021 tttagactag ctagatcgct accctacgta ctatttctgg tttttctttt tcaagcagga
     7081 gtagactatc tttacctctg aagattgcta gatgaaacat agactcacct ctttctattt
     7141 tactttaaat aagtgttcta gtaaggcttt catttacctt acgttcataa tatactacat
     7201 tggtcagaaa aggtcaagag ttttgacttt aactgaccaa tattttttta cactcttcga
     7261 aaacctcttc aaaccacatc agcttcgcct tgtctacaac ctcaaaacag tgttttgagc
     7321 tgacttcgtc agttctatca accatctcaa aactgtatag taaaatgaaa taagaacagg
     7381 ataaatcgtt caggacagtc aaatcgattt ctaaaaatgt tttagaagta gaggtgtact
     7441 attctagttt taatctacta tattttgagc agcctaaagt tagctttcta gtttgttctt
     7501 tgattttcat tgtgtattta aacacaaaaa caccctgaaa catcagggtg ccattcttac
     7561 atcaaatata aaattgcaag ggtcaggaga cttgctagaa gcccaactcc ccaaaagaag
     7621 aagtcaacct tccactcgct ccaaggattt cctttaccag acaatccccc aagctcaaaa
     7681 tggtgatgta caggcgtcat acggaaaata cgtttaccac ctgtcagttt gaaataactg
     7741 acttgcatca taacagaagt tgtttcaaaa acatatacaa ttccgataat caagagagtc
     7801 cattcttggt ggagagccat agagatagct gccagcatcc cacctagggc caaacttccc
     7861 acatcaccca taaagacctt agcaggctta tggttaaaga tgaaaaaact gagcaaacca
     7921 ccaatcatgg caagaatcac tagaagaata tccatctgac cttgcacata ggcaataact
     7981 ccataggcag acaaactaat cacaacggaa atactagcta aaccgtcaac accgtctgtc
     8041 aagtttactg cgtttgaaaa accgactagc cagaaaagag cgaagacaat atagaaaatc
     8101 cctagatgca cttgataacc aaagacagaa agcatatcgc caccgcgctc atagaaaaga
     8161 tagaagataa ctccacctag aagctgaaga gctaattttt gcttaggatt aagcccctca
     8221 ttgattttac gaaagacctt gagaaagtca tctaaaaatc cgaccaagcc atacaagacc
     8281 aagatgaaca aaatcattcc catattattg ctgaattggc tactaaatag ggcgaaaaag
     8341 aaagcaacca aaacagaagt aatcaagaaa accaaacctc ccattgtagg agtcccagct
     8401 tttgcctgat gctgtttgac atcctcatgc atctgctggc ctgtaatttg cgcctttcta
     8461 taaaattgga taaaggccgg aattcctact aaagttagta aaaatgtcac aattccagca
     8521 ctgatggaaa taaacatatt agtctcctaa agttaatgta atttttttaa tgtccttaat
     8581 agctgtgtta gcacgaacat cttgcttctg cacagtagag cccgaacctt gaaattcaag
     8641 ttctatattg agccacttag caagggtctc agcagtctcc tttgtccaac catacatatc
     8701 tggaacttcc tctactttat cagataagat aaggacttgc tgattcgggg caagattctt
     8761 cccttcttca gcagaactgt ttttaatctt cgttcctgtt cccacaacga tgggttgtac
     8821 aagattgcga cgcaattctt ctgctaaatc accaggtgaa atatccttga cactaggcat
     8881 aggataagga ctttgttgac ttacttgctc caaagcttta gctgttgttt gaagattgag
     8941 agagtctttc atagctgaag cccgctccaa gataggattg gcaaattctc ccaactgaat
     9001 acctgaataa tgttcaggtt gttggaccgt cacatacaag ataaaatcag gattttcagc
     9061 cggactcatc gatacagccg agaaaatata gtcggttaac ccgactagat aaccaccatt
     9121 tttctcgtca gcaatctgag ccgtaccaga cttgagggct acattttgcc caggaacagt
     9181 tacagttggc ttgcctgtgc tgtggttata catggttcca taaaccggat ccgtccctac
     9241 caaaaccatg ttagtccgag ttagactagc tgcatcttta gaaacaggat ttcccacaat
     9301 ttctttttga gatttccgag cagtttgatc atttggatca taaatggcac taataaattt
     9361 aggctccagc atgacaccgt cattagcaat agctgtaaag gcacgaatca tttgcgtctg
     9421 ggtcactgaa atcccttgtc caaatgagct ttgcgcaatg ttgacaatat tatccgcagg
     9481 aagctgacca gcatactcat ccgtcaaacc gaaacgggtc ggaactccaa acttaaaacg
     9541 attaagataa tcaagccagg tagcatctcc catcttttgc tcaaggaggg tcatcccaac
     9601 gttacttgag tgtgcaaaac cttgagaaaa agtcatcatt ctgccaccag tcaatccttc
     9661 attaacgtcc caatctcgaa tcgtggcatc tgcaattttt aactcactac tattaaagac
     9721 ttctcctcct ggaaaggtat tattatcaat agcagcagct aacatcatca ctttcatagt
     9781 ggaacctggc tcatagttac tttggtaaag gatatcacgc caaacaaagt cctctgtaat
     9841 gccttctttt gtatctgcat caaaggtcgg tcgttgcgtt gttgccagaa tttcccctgt
     9901 tttagcactg accaaagtcg ctgtcatgta ctttcctttt accttctctt gaaaagaatc
     9961 catctgggtt tccataaagg actggagggg gctggaaatg gttgtataaa catccttacc
    10021 atccatcgtt cgttgggaaa cttgttctgt tccgggtaca atattaccca gacgatcctt
    10081 ttcataggta ataatgccgt ctgtccctgc aagaatactg ttcaaggaac tctccattcc
    10141 agaggttccc agcaagctct tgcttccatc ttcattttca tggagttgag ctaggccgat
    10201 aaaactagaa gcaaattgtc cgtttgggta actacgattg ggactggttg taaaatcaat
    10261 ccccttgacc tctgcagctt ccaattcttt tttgatagac atcatattgg cataggtaat
    10321 cccatttccc tttgctccaa aggaaacttg cttgagatta ggttgcgaga gttgctctct
    10381 tacataggat tcttccatgt ccagatactt atgaaagacc tctgcaacct tgttaaattg
    10441 tgttttttct acgtaaagaa tcttacccgt tgctgactta tagttctcat caatgaccgc
    10501 atagacatta taggaggttg catcctcagc aatcgggact ccatttcggt cataaatagt
    10561 cccacgtttg gcaggaactg tacgggtggt ttgatgaacc ttcttagctt ccttcgctaa
    10621 atctgttcca aagcgagtgc ctgtcccaat aatgaccgca aaattgacta aaaaaatggc
    10681 aaaaacaaag acagataata aactcagact ttttccaact ctgcgtctgt tttcagccgg
    10741 cgatttccga tttttggtcg cataacggat tactcttttt gtccacttca tatcttactc
    10801 cgctattcta atattttcat tgtttaattg caaatcgtgt gaattggcaa tttctttcaa
    10861 acgttctgca cgtaatagtt cattgacctc ttgcttggca tcgtccaatt cggttttctt
    10921 ttcctctatc tgcgcattga tttttgtcaa atcattctgc acttgcaaga gcttggtctg
    10981 cataaaaata atactaatgg ctacaataag agtggttaca gcaatggaaa agtaaaaagc
    11041 tttttccaca cgcgaaaacc gtttaagttg catctgtagt atttgacctg ttttttccat
    11101 tttttctgcc atctttttcc ctcttacttg tgaatttttc tggccacgcg caacttggct
    11161 gagtgcgagc ggttattggc ttctaactct tccgcacttg gcaagattgg cttacgggac
    11221 accaattcca tcttgggctt gagatcatct gggatgaaag gcaagccttt tggaacttca
    11281 actgttgaag cttccttgaa caattgcttg gtcaagcggt cttctaagga atgaaaggta
    11341 atcactgaaa ttctaccatc cagagccaac atatccatag cctgctggat ggactcatct
    11401 gccgccccca gttcatcatt gacttcaatt cgaatagcct ggaaaatctg cttagcagga
    11461 tgccccttct tcttgagttc cttggcaggt ttgaccaact tgataatctc tgctaactca
    11521 gtcgttgtct caatcggctt cacttcacgc gcttgctcaa tcttacgcgc aatctgttta
    11581 gagaatttgt cctctccata cttgaagaaa atacgaacca agtcatgata gtcataattg
    11641 ttcaccactt cataggctgt cagactagca tcctgattca tccgcatgtc cagtggcgca
    11701 tcctttttat aagaaaaacc acgctcacgc tggtctaatt gaggactaga cactcccaag
    11761 tcataacaaa ttccatcaat ttcctgaaca ccagcttcgc gcaaacgtgc ctgtaaatga
    11821 cggaagttgt ccttgataaa ggtcaccatt cccttctcaa tgtaaggtgc caagcgtttt
    11881 tgcgcattgt caatggcatt ctgatcctgg tcaaaggcat agagatggcc tttttcactt
    11941 aatttactta ataaatactc gctatggcct gctccaccca aagtcgcatc aacgtagata
    12001 ccgtcaggtt ttacgtcaag catatcaatc gtttcgtgga gtaagaccgt tacatgatga
    12061 aattcttttg tcatatctta tctattttac cacaaatccg accagcttgc acttgtcaga
    12121 caaatagaac aaggagacta ctatttcttc aaaaaatatg tcaaaaatac ttgacacttt
    12181 atgtttaaaa gactataaca aagtcaaata tatacgacat aaatcagaaa ggagaccaga
    12241 tgaatcgtgt gaaagaattt cgcaaggaac tgggcatttc ccagctcgag ctcgccaagg
    12301 atatcggtgt ctcgagacag accatcaata tgattgaaaa cgacaagtac aatccaactc
    12361 tggaactctg tctcaatctc gcccgcagcc tccaaactga cctcaacagt ctcttttgga
    12421 aggaagattt ttaaaaaagg agcaaactca tgaaaaaaga aaccttcact gaaaaactga
    12481 tcaaacgcac atacggtatt tctggtcccc ttgacgaata caaacggcgt gaggccgata
    12541 gtattgggaa ccaagtcttt atcgtcctct tttatctgat gattttcgga aatcttattc
    12601 cactccttct ggcctataaa taccctcaag aagtggctct aatctatcct cctctgattt
    12661 tagtgattgc cctcatcgct tctggctatg tcacctacca aatgaaaaaa acaggcatca
    12721 cagtcattga accagatatg ctgaatgaga aagaaagcaa gcaactacac tacccaggtc
    12781 tgaaagcagg tttgttcttt ggtctatgga tgttttttat aactcctctt ctcaggatac
    12841 tcataggtga aggtcaggac tattttcatt ctcttctcac tataagaaat ggtgtatcaa
    12901 gcattctcgg ttctattttc ttcggagcga gcatacagtt cctcatctcc cgtcgcattg
    12961 caaaaactaa gaaaaatcaa gatgaggatt aggaggtgcc ctatgaaaaa agaaaagaga
    13021 cagttacgtt atcctggtct gaaagcaggt tcgatttatg gaacagtgat attttttata
    13081 attccactca ttgataccct aacaagtgaa aatccaaatt ttatcagttc tcttctaaat
    13141 acaaaacata tttttaaaac tatactggga gctttctttt tcggagtgat gatacatatt
    13201 gtcgactcac ttcgtattgc aagagctaaa aaagaccagg attaggaggt gccttatgaa
    13261 atcactagct agactactga tcattcatgt ttttatcagt attttccttt tcttcgccct
    13321 tatttcagga gctgtttctc atacagtttt actactccta ctcctctttc ttcctgcgct
    13381 caataaagga cttgagaaaa tacaatcaaa acggatacct gtcctaaacg cagccctctt
    13441 ctttctcctc atatcctttc cacaactttt aaccaaccct gtccaatgga aattttcaat
    13501 attcctagtc gtaaccatca tttcaagttt ggcctacttc tataactttt atcaagtagt
    13561 taaagaagta gatcaaaaac agttgattta ggagcttgct cccataattt ctcatttcat
    13621 aggcaaataa tcccacctag cttgttctag gtgggattat tttatttctt aacagagatt
    13681 gcaagtcatt ttcctttatt ttagaaagtc gactctttcc aattcacact acaatccaaa
    13741 acttgttgcc tttcttcttg attgcggcct tcaatctggt caatcaaaat ctttgtagcc
    13801 tgttgtcctt cctcaaagga gggctgaacc agcgtcgaaa cacttggaga agaaaagcaa
    13861 gtccactccg tattgtcaaa accaatcaac ccaacttgcg gcaagttata attcaactcc
    13921 ttgataacgg taaagactag aggtagggcc caacagttag ggataaatac cagagttttt
    13981 tcatcgggat cgatttcttt ttgtaaaaat tctttaattt gttccaaatt cgtatgctta
    14041 tcttcaatgg ttagactggc gtgacgcata ttagcatctg ttaaagcatc cacaaaacca
    14101 cttgcccgct caatccgagt actcaaacga ctcgtatccg ctgtaatcaa gagaaaatgc
    14161 tcataacctt tttcgataca ggactgggtc atgtcataaa cggcatcata gttattggtt
    14221 ttaacccagc tagtccggtg ttcatagagc tgactatcaa aaaagaccat tttcttcttt
    14281 ttctcatcga tgatacgaga atattttcgg aaattagagg tcggctgaat aataaagccg
    14341 tctactccca agagaagcat gctttcaata taccggtcct cactctcttg gctgtaatta
    14401 ctatttccta tcattacctg gtagccattc tggctggcga tatcctcaat tcccttaaca
    14461 atttggtttg agaaactgtt ggtaatatca ccgatcaaaa caccgattaa ttttgttcgt
    14521 ttggagttta agctacgcgc aacaatgctc ggtttgtaat ttgtttcatg aataactttt
    14581 tcaatctttt cacgtgtctc ttgggacatt ttttcatatt tcccgtttag gtaaaatgac
    14641 acggttgttt tcgaggtctg agccatttcc gcaatgtctt ttatggtcag tttcttctcc
    14701 aatctaaaac acctcctact aatacttatt ataacatatt cactattcaa aatgcctatt
    14761 tctagcactg caagcgaatc attctctcat ttattttatc atatactaga cattttccac
    14821 gcatttttgt tccgtcaacg aggcacaatt tttcacctac accaatatcc tcgcttaata
    14881 acagaatcag cttgtctgtt tcgtcatttt tcacttcaaa agccagagca ttttccactt
    14941 cacgatcatc tgtctggtag acagaatgac ggatgatttc aaaactctca tgcgcaatga
    15001 tggtataatc cagcatctga ttctcaaaga attggcgctt ggtgagtttg ctacttcttt
    15061 caagctcatt gtatttagga gaaatgatgg tatcttccaa atcaaaatca acttcactcc
    15121 atagtctcaa ctgattgatt ttcccatctt gataggtcac atccttgtca aggataaact
    15181 gagtcaacgc ctcatgctga ccttgacacc tgatgtcatc taccaagagc cagacatcct
    15241 ctaccaacat gaggattttt ctcttgtgaa gataaggcaa atcaggttct gctgaccaat
    15301 aagccccctc aatataatgc actccctccc tttctttatg gtgacaaaac agggagtgag
    15361 gatagtattc atattcccag gatcccgtga ttctttccgg agctttccca tctacaatgc
    15421 aggtcgaatg actccaagca ctctttaaga gataacgttc atatatctcc cgataagaat
    15481 aacgcccagc atctatgaaa ataggttggc tttgatactg taagcaaaaa ctattctcgt
    15541 cactatggct atgggcactt cctagcggac catttttgaa aaatagataa cgatgttcat
    15601 ccttaatgca gacatgtcca gagtcttcaa agatcatgga cttaggctgc caagctctct
    15661 tttcaaattc ctgcagtcgc ttgacctttt ctcgccccag gaacaagagg ctaagcaaat
    15721 caactttaac atccagaccg ttaagaaggt cttccttgtt caaaaccaca gcagacaggc
    15781 tcaacatttc tgtcgtttct gtagaatcgc tatcaccaaa agccaaagtt cgtccatcta
    15841 agcctgtcat catttgaata taggtcgcca tcttttccag caactctcgg taactatctt
    15901 gcaagtctgg aagcaagaga cacaaatcca gtaaggcttt ataaacctct acatgataga
    15961 gaatcgactg ttcaaactgg cttccatctc ctaaaatctg tgtctcaatt tgctgtttca
    16021 actcctctga agcaaaatgg taagcttctt ctaggtccat cttatctgaa aagaaataat
    16081 agatagcaag catcggaatt gtttgtaaaa tcccccagtt actaagggtg tacttggcgc
    16141 gatagtggct tttcataaag tcaatctgct tttctagact gaccaaaatt ttctctagtt
    16201 ctttctcctc tagcaagtca aatttcaaga ggagcaagag tagtttcaac caagtaaagg
    16261 aacgaatacc cgtatccaag gttctagtca tcaaggattg aggagaaaat tctctcacct
    16321 gctcaatcca atcaaataga aagaacttgc acttttgaat atagtcctta tctccttcta
    16381 ccatataccc tatcataaac tgcaagagat attcttgtcg attgagcata taagcccatt
    16441 ctggatcatc ttcaaatact tgatcccata ccatcggttg gatttgatgg atttttgaac
    16501 aaggctccat atcccaagga ctatcaaaca taaaacgatt gtccatcaag cgttcaaggg
    16561 aactcttgac tttctcatag tcttttgaac agtgggacaa gatataatca cgacattggt
    16621 ttccatcgat tctttcaaaa aattgtcttc tttcttcttt cattatctat taccagaaaa
    16681 agaactactt aaaaagcagt tcttttgtct ttcccattac actttccttt tctacatgga
    16741 ggaccacacc ttttgcaatc tgcaaggaga ccaagtcatc ttggatagaa atgatttttc
    16801 catgaattcc agacaataac aacacttcat caccagatgt taaagaagct aaatactctt
    16861 gtcgttgctc catctgtttg cgaagcaact tttgctgacg aatagaatga aagcttgaca
    16921 gtaaaagggg actcactgcc aagacaatca ctattccata aaacaatgtt gtatccatta
    16981 agctataatc ttaagccagc ttccgataat tccgatgata actgttaaaa taacgagttt
    17041 atatgttgtc catttctttt ctttgatcaa gtagtaaact aaaagtgtaa atagggctgg
    17101 tagaagagct ggagcaacct tatcaagcat tccctgaata cttacgatac tttgtttagc
    17161 gtctgcttta acttcccctg cagcaaaggt aatcggcacc ataatcttaa cagatgtcgc
    17221 tgccaaacca gcaattacgg ttacaccgat aatattggca atacgagaaa tcgttgccat
    17281 ctgttcgctt agtttatcaa tcacagttgt tcctagtttg tatccataca gaccagttga
    17341 caatttaatc gctgttaaaa tcgtattcat cgcaaggaag aacaagattg gaccgacaac
    17401 caagccttct tgagcaaacg aagctgcgat ggttgagaac aatggagcta aacagaattg
    17461 agagagagaa tccccaatac ctgccaatgg tcccatcaag gccatcttga tgctacgtgt
    17521 ttcttttgtt ggtcggccat tttccaacat tacaaggtgc aagctggtaa taaaaggcag
    17581 gaagtgtgga ttggtattat agaattcaca gttttcttcc aaggcttggt agaaaccttc
    17641 ctgatcctct ccatagtgtt ttttcaaagc aggatacatc acattggcat atcccaaccc
    17701 ttgatagtta ctatagttaa atccattttg acaaaagaat gcccgcaaag acgttttaag
    17761 ataatcacgt tttgttaatt tgttagatcc agtcatcgtg tgcttcctcc tctaccacat
    17821 gatccgctgt ttttggcttg ttataaaatt caatcaaagc aaagatagta cctacaattg
    17881 caataccaat tgttgggatg tttagataag ctgcacaaac atatcccaac aagacaaagg
    17941 gaatcaactc tttcttagcc atcactgaca agatcatcgc aaaaccgata gctgggagca
    18001 ttttaccagc aactgtcaaa cctgtaagca ataccggtgg aatgtagtct acgagtttca
    18061 acaaggtatc cattgaaagg gcacccaagc aacccaaggt aaatccaata aaggcaaaca
    18121 accaaattgt tgcatttaga gtgaacttaa atttcttcaa attatggttt ttcaagtgct
    18181 tcatcgccgt ttcaggcgca ccagcacgta cagtgtaggc gaaagtttgt aagaattgaa
    18241 tcgccacagc aatcggagta gagagggcaa gagccgcttc tggactgact ttaccagcac
    18301 tagtgatagc catcaaggta ccaaagatac caggtccgat tgggtttggt ggaacagtac
    18361 ctccagcacc aacaccgaat cccatataag ccaattcacc aatagctccc attgcaagag
    18421 cagtaggcag atcacctaga ataattccga caccaaatga cagaacaatg catctattgg
    18481 tgtaaattcc taacagcatt ccactaaaac agaaagctgt ccataatcca attaaaatcg
    18541 cttgaaatac attaatcgac ataacgatct cctcttttaa atatagtcca taatgttgac
    18601 ttgaacagct ccatcatttc ctgttggagt tgttttcgta ttaaatgtta cttgatgagt
    18661 ttggctcaat tccttgaggg ctgccttgtc ctcttcaccc aggaagatgg agcgtgtcac
    18721 ttgctcttta ccagtagcat tgtgaatgtt cccaatattg atttctttga tagggacacc
    18781 accttctacc aaggttaaag cgtcctttac atcctttaca acgataaaga tcgtttgagc
    18841 aggattagcc ttgtgaatga tagcaatcac cttttgcaaa gggaagaaac gcatggcaac
    18901 tgagtctggc acaactgttt tcatcagagt ttgttgcatc ttgtccgtgc ttacttcatc
    18961 attggcaaca atgaccgtat tacaacctag gtattttacc caaagttgtc cttgtccatg
    19021 aatcaaccgt tcatcgatac gggtcataat aatatttggc attgtcatat ttctcctcct
    19081 accaatatag gttccagtct ttgtagaaac ggataagggc ttctaggtaa tagtagtcac
    19141 cccagatatt gccttcatcc actcctttac ctgaatgcca tgagtacaca ccgtggagga
    19201 gacttgtccc accaggggta aattgatcat ttgcataatg ttcgatcaag gaacgaagca
    19261 tggcatgcat agcatgttta taaatatctt tgtcagcatc cacctctggg agatgtttta
    19321 gcatttcatg aatcccacag acggcgatag ctgttgctga agaatctcgt gattgatcac
    19381 taccatcatt aaaaatcaaa tcccaatagg acacatgatc ttttggcaga cgattcaaga
    19441 aataattggt cacaccctta aacaagtcaa agcaggactc gtcttttaag tgacgataag
    19501 tcaaaggaat accatagact ccccatgatt gaccacgtgc ccagcatgaa tcatcactat
    19561 acccttgtct cgttacacct ttaaagggtt gacctgtctc aggatcaaaa tagaaggtgt
    19621 ggaaggacga agcgtcatca cggattacat tattagctga agcatagaaa tggctttctg
    19681 caatatcgta gtatttttga tcgcctgttt cttgataagc aaagaataag agttggatat
    19741 tgagcaagca gtcgataatc aaacggtaat gctctttctt gcccaagtct ccccaagctt
    19801 gaataaaacc acctttttct tgatagcgtt caatcaactt atctgcagct ttcaaggttg
    19861 cttctctagc ctctccatct ccatttatct tatattcagc catacaagac ggtgtgtaca
    19921 agaagccgag atcatgatga tccaattcta ctctcttatt gacacgatcc aggaaagaaa
    19981 gaacattttt atgagcgatg tttttaaatg catcctgttg actgtattca taagccaacc
    20041 acagttctcc tgtccagaaa ccattggtcc attccgtgtt atccatgatt ggatagacat
    20101 tatcaaaggt agctggcgtc gggaaatctt ccttgaaata gtcaaggttg agttctaact
    20161 gccgaataac cttatcgatt gcctggccga cttcttcttt cgtcagaagt ggtacttcta
    20221 agaagcgctc aggcgacttt attttttcaa tcgtaacctt ttttatcatt ctttcaccct
    20281 ttaaataccc gattcgaaat cttcttcctc ttcctctgca tccgttgaaa acaattcttt
    20341 accatttacg actccgccct gggccgccac tactgattta ttaacaacct catcaaagct
    20401 atgagccatt ctagcaaaga ctgcttccat taacatggct aagttcaaac ccgagagaac
    20461 attcattgtt ttggctggat tttctcccat tatggtagaa gaaaccttga atggcgatcc
    20521 tcccaagaga tcacttagga ttaaaacttc ttcttcattt gaaattgcaa gtaagatttt
    20581 ttgcttgagt tcatctgctg acattccttc cacaaagtca atcgcctcca cattttcttg
    20641 attgcctgca atcaattgta aagaactata aatccctgta gcaaaatgtc catgccctac
    20701 aagtacaatt ttcatctttt ctcctttctt gtttaggttt accggtttac tttatattcc
    20761 ccattgtaat cctttatttt tatcttgtca atagtttttt taaaaaaaaa tattagcgct
    20821 ttcattatct ttttaatcat tttaatagac agaaatttca aaatattcca tttttaagga
    20881 aaataaatct ttttataaat aaaaatattt atttattgac aaaaccggtt tactagaata
    20941 taatttgatt atagagaagt cttaacaaat ttgaaaggaa gtatcaaatg acaaatacat
    21001 cattctcaat tgagcagttt tctttaaaag gaaaaattgc tctcatcacc ggcgcttctt
    21061 atggaattgg atttgctatt gccaaatcct acgctgaagc cggcgctact attgtcttta
    21121 acgatatcaa tcaagatctg gtcaataaag ggattgaagc ttatcgtgaa gttggcatcg
    21181 aagcccatgg atatgtctgt gacgtgacag acgaggacgg tatccaagcc atggtcaagc
    21241 aaatcgaaca agaggttggt gtcattgaca tcctcgttaa taacgctggt attatccgcc
    21301 gagttccaat gtgcgaaatg agcgccgctg atttccgtaa ggtcatcgat attgacttaa
    21361 acgcaccatt tatcgtttca aaggcagtta ttccttctat gataaagaaa gggcatggaa
    21421 agattatcaa tatttgttcg atgatgagcg aactgggacg tgaaacagtt agcgcttatg
    21481 ctgctgctaa agggggcttg aaaatgttga cccgcaacat tgcgtctgaa tatggtggag
    21541 ccaatatcca atgtaacgga attggaccgg gttatattgc cactcctcaa acagcacctc
    21601 ttcgtgagtt gcaagaagat ggttctcgcc acccatttga ccagttcatc attgcaaaaa
    21661 cacctgctgc acgttgggga aatcctgaag atttgatggg ccctgctgtc tttctcgcta
    21721 gtgatgccag caattttgtc aatggccaca tcctatatgt agatggcggt atcttagcct
    21781 acatcggaaa acaacctgag taaaaataga aagaagatct tatgaaaatc gcattaatca
    21841 atgaaaatag tcaagctagc aagaatcaca ttatttacga tagtctaaaa gaagcgacag
    21901 ataaaaaggg ctaccaatta tttaactatg gtatgcgtgg agaagaagga gaaagtcaat
    21961 taacttatgt gcagaacgga ctaatggctg ccatcctttt aaatacaaag gcagttgact
    22021 ttgttgttac tggctgtggt acgggtgtag gggctatgct tgctttaaac agcttccctg
    22081 gtgttgtctg tggtctagca gtggacccaa ctgacgctta cctttattct caaatcaatg
    22141 gtggtaacgc cttgtctatc ccttatgcca aagggtttgg ctggggggca gaactgaccc
    22201 tcaaattgat gtttgaacgc ttatttgctg aagaaatggg cggtggctac ccaagagaac
    22261 gtgtaatccc tgaacaacgc aacgctcgta tcttaaacga ggtgaaacaa atcacccaca
    22321 atgatttgat gatcatcctt aaaacaatcg accaagactt cctcaaagac accatctctg
    22381 gcaaatattt ccaagaatac ttctttgaaa actgccaaga tgatgaagtc gctgcttatt
    22441 tgaaagaagt attagccaag taaagctatt ctaaaccaga aaggaactaa tggatgacga
    22501 aaatattact gtttggcgaa ccattaattc gaatttcacc attagatgcc accagtatcg
    22561 gcgatcatgt tgccagttcg acttattttg gcggatcaga aattaacatc gcttgtaatt
    22621 tgcaagccct gggtatctca acgaaagtct ttaccgcact ccctgccaac gagattggag
    22681 atcgttttct cacattcttg aaacagcacc aaatcgatac cagttcaatc tgtcggcttg
    22741 gcgatcgaat cggcctctac tatttggaga acggctttgg ttgtcgtcaa agtgaagttt
    22801 tctacgatcg taagcatacg agtatcagcc agattcggcc aaacatgcta gatatggatt
    22861 ctctctttca ggggattagc cattttcatt ttagtggaat caccgtagct atcggtcaag
    22921 aggtccgtgc gatccttctc ctactcttgg aagaagccaa gcgccgagga attgtcgttt
    22981 caatggatct caatctgaga acaaagatga tttcagtcct agaagccaag tatgaatttt
    23041 ctaagtttgc acgttttact gactattgct tcggtattga tcctctcatg attgatgacc
    23101 aaaatctaga gatgtttcca agagacagtg ctagcctaga agaggtggaa aatcgcatgc
    23161 gacttttaaa agaagcctat ggtttcaagg ccattttcca taccctccgc tctagtgatg
    23221 agcaagacaa aaatgtctat caagcctatg ctctggaaga acgatttgaa gagtctgtcc
    23281 aactaaaaac tgcagtctat caacgaattg gtagcgggga tgcctttata tccggtgccc
    23341 tttaccaact actccatcat tcctccctaa aaactaccat tgactttgca gttgcgagcg
    23401 caactctcaa atgcactctt ccaggagacc atctctccac ttccgcaact agtattgaaa
    23461 atttactggc aaatgcacaa gatatcattc gttaggagaa ttacatgacc aaatcagata
    23521 cgattattga actaaaaaaa cagaaaattg tcgctgtcat tcgaggaaat acaaaggaag
    23581 aaggactaca agcctcgatt gcttgtatca agggcggtat caaagctatt gaaatcgcct
    23641 ataccaatca gtatgcagga caaatcatca aggaacttgt agacttgtat caggacgatc
    23701 agagtgtttg tatcggtgca ggtactgtgc ttgatgccgt aactgctaga gatgccattc
    23761 tagctggagc aaattacgtt gtttctccat ctttccatgc tgaaactgcg aaaatgtgca
    23821 atctctacag cacaccgtac attccaggct gtattaccct cacagagatc acgactgcac
    23881 ttgaagccgg tagtgaaatc atcaaactct tcccaggtag tactctcagt ccagcatata
    23941 tctctgcagt caaggcaccg atcccacaag tttccgtaat ggtaaccgga ggagtcggcc
    24001 taaacaacat ccctcaatgg ttcgctgctg gtgcagatgc cgttggaatt ggtggcgaac
    24061 tcaataaact cgcttcccaa ggcaactttg accgcatcag cgagattgcc caacagtata
    24121 ttacactcag ataaaatcat aactacccgt ctaacgggtg gtttatctca gagctataag
    24181 cccaaatcat cagccagcgc ctaaagacgc tggctttcac gttgttcaag ccttattgct
    24241 cttgactcgt cacttgcctc tttaagagac tttggtatta cttaccacta tccctaaagg
    24301 gatcctcata ttcttttaca ctcaatttat ctagtgctat agtagattga aactggaata
    24361 gtacacctct gcttctaaaa cattgttaga aatcgatttg actgtcctga tcgattttgt
    24421 cctgttctta tttcatttta ctatatatca tgctttactc gttctcaata tcatgcttta
    24481 ctcgttctca aattttcata ctcgtgaaga aatcatccac tggataattt ctttaatctt
    24541 gactatattt cttaattgtg gctttattaa gccctactgt acttacaaaa taaccttccg
    24601 cccagaaatg ccgattccca aacttgtact tgagattggc gtgtttgtca aacatcatga
    24661 gtgcactttt gccttttaaa tacccataaa acttgaaaca cttagcctta gtggaatact
    24721 gactaacatg tgtacatggt ctggcattaa gtgaccctcg atcatttcaa cacctttata
    24781 actacacaag cgatgaaata tttcgcccaa actacttcta tattgattat agatgacttt
    24841 tcgtctatac ttaggggtga acacaatatg atagaacaca tccactttgt gtatgataaa
    24901 ctatgagtct tttgtgccat attttttctc ccttcgcttt acaagtggag tgaacacctt
    24961 tattgtatcg tgtttggagt ttttttggta taaccttcga cgcgcacccg catagcgggt
    25021 ggttgttttg tctcgcacct cacggagcga gacggactaa tatagtggag tgaaatagga
    25081 tacgaacaaa ttgattagga aaatcaaatg aatttataga aatcttttag cagttatgac
    25141 gtcctattct agtttcaaaa cgctatagtc acataatgaa gtaaaaaagg ataagtatca
    25201 acttatcctt ttttaaaaga aaaatccgaa gatatttggc cttcttcgga ttttttctat
    25261 tttccacagt ttcatgtaat tcatctagat gatgaacaaa ttagttgttc tttcctctac
    25321 ggaataaata aaacgcccca agtagcaaga accctagact tgccaagatt gactgacctt
    25381 ctcctgtctg agggagattc ttttgatccg aatgattctt ttcctcttca gatttttcct
    25441 tttcttttga attctgtact tgcggctgag ctgcttgctc tagcttttta aagacttcct
    25501 gatctggagc tgattcctgg gtttcaggat tatagtaggc aatcttatat tcattccctt
    25561 cttttcgaat ggtatagact ccacgtttca aaacttggaa ttggttggaa atagtagaga
    25621 cagaatcatc atatttcaca atgccccaaa ctccttgttt ggcatcataa acagactgaa
    25681 gggtttcgtt attttcgatg aagctacttt ctaactcttt tatcatttga ttgaaggtgg
    25741 cacgatccac attagggatg agcatatagc cataagaatc tccattttgc ttatgagcct
    25801 gactaatcgt aagaaattca ttttcaactt ccttgtctga ctgtccttca ttgatatcct
    25861 tccaggctcc cttttgcaaa gccttactca tactgattga actcttctta aagaaaaagt
    25921 aaccaatatt ctttttcgaa tcggacgatt ctaaaaagac actttgggtt tcaggataat
    25981 ccttttcttg ttctgtaagg gaggcttctt tatcattgac atagacttta tatggattac
    26041 ttgattccag ttttctctgg tcaattgtag ttgcagcagt atctgttgaa gtgttttgga
    26101 tattgcttcc taaaaaggcg atcttatcct tcaacataaa ccagctctta tgagcagtca
    26161 atgtttgatt ccagttggtg aaatccatgg ttgctgtcgc attggcatca tctagtttga
    26221 ccgttccaac gaaagcagac ggtagaactt tacctgtatc gctatccgct ctcttagcat
    26281 ccgtctctgt tgtaccaggc atcttatatg gattgactgt tggccagtag ccatcgctat
    26341 agtgactcaa atcgccattg taaagataga acatcccatc actcgtatac caaccacgtt
    26401 tattttcctt gttcatatgt tcgtaattca aggtacgact ggaaaagagt gacaagccaa
    26461 atccaaaccc tttctctgca ttgtacatgg ctgttttatc catcttgtta aaggcagata
    26521 ggtaacttgg tcttggaaca cttgcgactc ctgcatcact taacaaggat tgcatcaaac
    26581 tgatatcctt ataagtcttc aaattcttaa agacatcata ataactatcc gattgaacaa
    26641 tggtcttcac aagactctgc aaacgttgtt tggtttctcc ttcagacata tccgctattc
    26701 ggtgaatccc tcttagtact tctactgcgg ccacgtgccc ctcgctattt gcacgactga
    26761 tcgagcgtcc acgactcata tccatcagct ctccattcac cagcaaagga gcaaacgatt
    26821 tatcaatcca gtggtacatg gtttgcattt tatctttatc gattggattc ttggtctttt
    26881 gaatgactgg caacagttga gacaggccat caatcaaaac attcccataa gcacccgtat
    26941 aggcaacatt ggtgtggtcg atataggatc catcttgata aaaaccttca ccttggtcta
    27001 ccaacttgaa cacttgctca atcgagcgaa tggtagaaga aatttcttga tcatccttac
    27061 gcagtaaacc agctattact tttacccttc ccatatcaac taagtttcca cctagagcct
    27121 tgaatgggtt atcagtcgtc tttcggaaat gttcgggatc tggtacaaat ttttcaatca
    27181 catctgtata ttttttaatt tcctcatcag agaagtattc tttcatcaga gacaaggtat
    27241 tgttgatggc acgaggtgta ccgatttcat aatcccacca gttcccaaca atgctctttt
    27301 cactattgta gacatgttta tgcatccatt ccatggaatc cctgactgtt cgaacgacag
    27361 tttcatcttg ataataacga gaagaaggat tggtcacttg cttggccatc tcctccaatt
    27421 tccgataagt ggcagtcaga tttgcagaca ttttataatt tgaaaatttt tcccacaaat
    27481 aggtgcggtc cgcctgactt gaaatactag ataggctatc agctaccttt ccttccaatt
    27541 cctggtttaa tttggccatc tgttcatttt tagaatcata atgttgattc ccagcgatga
    27601 tgccattcca gtcatccaaa cggtctgtgt atgtatcctt aacagaggct agaatcttca
    27661 aaggaatctt tttcacttcc ttgccatctt tactgacaat gacattggtt gtccctccct
    27721 taagaggttc taaaattcca tttttgactg aagcaaggtc aggattttct accttataag
    27781 tatagtccgc aagagaaaaa acatgttttt ttccaattgg taaatcaatc ttttcctcaa
    27841 gctgtttatc tgtttgagaa tcctcagaaa gctgggctgc tacctctacc agctcaatat
    27901 ccttaaagga aacagtccca gttcctgttt catagaataa ctccagcttg attttatcaa
    27961 catctaaagt cgggctatag tctgcttcaa tggtctgcca gtcctttgtt cctgacgtcg
    28021 ttgcagaatt ccacaatcgc ttgtccttac cactttcctc aatgatacga actttggcaa
    28081 tcccgatttt attatctgtt ttaatcttga aacgcagttt atactttttc ttaacttcaa
    28141 taggaaccat acggtgaagc gctgccctta atttctcatg gcttgagata gtgatagccc
    28201 catccttagc ctcaatgact cgagttgagg catctgcaga actattcttc tggtctaccc
    28261 aagctgacca cccctgagct ttgcttcctg tccacgaact gcttccgtcc tccgtctgac
    28321 caaaatcacc attttcaact aaattttttg tatccctttg ctgatactga acttccttct
    28381 ggctttgctg aatggtattc gtagtcgttt cttccgctcc aactgtcata taatggttta
    28441 ataaaaatcc tgataaaaca agtgaagaca aactcacaat gagcttcttt gtttttgttt
    28501 gcatgtatac actccaataa acatattgta aaatcaatag gaactaaatc tcaaattaga
    28561 gatttatagc aactaagtaa accggtttag ttaaatcata ccatttttaa agttatttgt
    28621 aaacgatttc tatcatattg agggcttatt cttcaacaat atcttccatc cgactcgacg
    28681 aaaaaagtaa aaactgttac aatgtagaaa aagaaaagag gccttcatga cttcacttta
    28741 tgatttttcc gttttgaacc aaaacaacca agcaactccc ttggatagct atcgtggcaa
    28801 agttctcttg attgtcaaca ctgctactgg atgtggttta acgccccagt accagggact
    28861 tcaagaactc tatgaacgct atcaagatca gggcttcgaa atattggatt tcccttgcaa
    28921 tcagtttatg ggacaagcac ccggcagcgc agaggaaatc aacgccttct gtaacctaca
    28981 ttttcaaacc accttcccac gttttgccaa gattaaggtc aacggtaagg aagcagaccc
    29041 tctctatgtc tggttaaaag accagaaatc tggcccacta ggaaaacgag tcgaatggaa
    29101 tttcgctaag tttctcatcg gtcgagatgg gcaagtcttt gaacgctttt cttcaaaaac
    29161 agacccaaaa caaattgaag aggcgataca aactctacta taattcacaa tctcactatg
    29221 attaggtttc ctttaacctg atgaatagtg agattttttg atgggctttg acttaaatag
    29281 aaaaacaccc catgatatga aacatgaagt gttgtaaagt ctatgttgta ggtgcttatt
    29341 tcacaatttc aatgtgacca gtgataacga ataccataca gaatcttcat atacactaaa
    29401 caaatgactt tctaattatt tcaattagtt ttggctagta aatatcattt ccaacaaacg
    29461 ccctctcaat tccttatcct gatgatgcaa gatattcatt aagtcatgag agtttttggc
    29521 attgatgaat tgatttaaca atctatcttt taattcatat ggaagagaag ctgtctttag
    29581 tagtctaaaa acttcgtcat ttaaagatgt ccttttatta tctttccatt caaatttagc
    29641 tgtatcattc ttatttggca attcaattat agacacattc gttcctttaa aatgaattct
    29701 atgttttcta ttgcttggaa cgatactaga atctccttgt aatgctaact ctaccattcc
    29761 catttcccaa tcgattgata atcttgtttt atatctttga ccattttgat cttcaagcat
    29821 ttcaaaagaa tgttgtttcc ctgggaatac ataccaatct acaacctcag gtaaatcaac
    29881 acccatacct atctcagaac caaccaaggg aatgattgca ccactttttg caaacacagg
    29941 cgtagtcgag atgtccctat aaacacttaa cttcacacca cctgtgtatt ttttctctga
    30001 aaagaagtca taccattcac cttcagggaa ccatacatct acttttccag attggaatgt
    30061 caaatccatc ttttctacaa tgggagccac catcagttct gttccaaaaa agtattggtt
    30121 tggaacatta tagctctcat cattctctgg atagaaataa tagattggac tgattaatgg
    30181 ggcaccttcc tcatgtgtct ttacattcat ggtatataga tagggaatca tctgatgtct
    30241 caaacgaagg tatttcttca taatcttaga tgttgtttct gaaaagaacc aaggttcttt
    30301 actattaaaa ggacttctag aactatgtaa tcgagtaatc ggactaaaaa caccaaactg
    30361 tagccatcta gtttgtagct cttcgtcata atcccccaac atatgtccac cgatatcatg
    30421 actccaccaa ctataaccga tattagatgc tgtcgctgta aaatagggtt aaaatcttaa
    30481 ggaattccaa ctaataatag tatcccctga aaaaccaaca gggtagcggt gactaccagg
    30541 acctgcatat cttgataaaa tcaaaccacc ttctgcattt ttacaactat cctgatagtg
    30601 ataatggttt aaaagccaaa gtggatctag cataccttgt gtcccttgtt gccagtcaat
    30661 ccaccaaaaa tctactccct gcttttctag ctcataatga acatctttaa agtaggcttc
    30721 cctaaaagag ggattaaaaa aatcaaaaat agcaggttct tctagttcta catttaaccc
    30781 caaccgtttt gcgatttgag gataagcttc ttcataagcc cgtatcccat cagcaggatg
    30841 gacatttaag gagagtttta actttctatc atgaagttgt tgcaataact gttctggatt
    30901 tggtattaag tttctattcc aactatatcc tgtccagcca cttccaaaac gagctggaat
    30961 gtcagttata tgccaatcca tatctaacac accgatagat aatggaattt tctctgtttc
    31021 aaatctgtct attaaatcca agtattcatc cgacgtataa ggccaatatc tactccacca
    31081 attgcctaaa gcatatcttg gcaacaaggg tgttgaacca gtcaaatggt aaaagtctct
    31141 gattgctcct ctataatcat gcccataggc aaagaaatac aggtcaattt gattttctct
    31201 ctcaatataa ccagattgtt catcccaaat aaatccttga gaatcatcca ataaggctat
    31261 accatttcgg ctaataattc catcttctaa cgagattgct ccatctgcct tatccagagt
    31321 ccgagctgtt ccttttaacg tttcaataga ttcaccaaaa taccagcgac taccatatac
    31381 ggcaaaattt ccttttaatt ctataaataa attttcggcg ttaaattctc ctttattaaa
    31441 gtgcagatga aaatagtccg tcataatatc tagtacattt gatgtctcga tataatctaa
    31501 cgaaacttgg ccaaaatctc tattatagat aagttgtgtc gttctatcct caaaatttcc
    31561 agttcgagag tattctaacc ttactagctt gtctgttaat acagagattc gataaaactc
    31621 tcccttaaaa attttcaatt tgttttcctc cttttatggt agcataaaaa cagaacgcac
    31681 catttttgat gcgtttttca ttattctgaa tgcaatgttc tatctgttat atctatgaca
    31741 aataatagtc aattgaaaaa aatgtagtgg acaaaatatc ttttaacaaa ccaagagttt
    31801 attaaagagt tatcactttt caacttttct aagcttatgc agttgtgaaa caaactactt
    31861 ttaaactatt aactaagata ggattgataa ataatttcaa actcttacta gcaatcatac
    31921 gatattcaag ctcgcgtgct tttttccttc ctgcttattt cttagaactg aagaacccgg
    31981 atcggtatat aaattatccg gatcaacata gtcataagac tcataacagt tgcgcttcat
    32041 taagtcatcc ccagagcaag agcttcatct cgtaattttt caacatcact aaccgtaggt
    32101 cgccatcctt caatcatatt tgtacttaaa gcataccaaa cactcttaaa aacggatcgg
    32161 ttttcaaaag ctattcccat gattgtcatc ttttctttat ctatatctaa ggacatatgc
    32221 tacctccttt agatacatta taccatgttt ctctgtagct tttaaaaatt ttattttgtt
    32281 tgtcatatct aagttttcag tacgcttatc ctattttata agcctcaaac ccaaatataa
    32341 aacgcattaa ccatctgata atatgcgttt tattgtggaa acatttccca ttttctctat
    32401 ttctaatgac ttacttcaac ttctgacttc atggaaaaaa caacaaaaat atgaactggc
    32461 aaagtttggt atcatcagta atccagaaca attcatcttt acttacatag ataccaaagg
    32521 caatatcaat aaacctttac attctgacta tctcaataat aagatgaaaa ctatcagaaa
    32581 acgacaccca gagcttacac acgctacgcc acacaaacta cgtcataccg gagcaacgct
    32641 cgctaaacaa gcaggaatga gcttagaagc catttctgaa gctctaatac atagcgacac
    32701 aggtacaaca cagatttatg tcaatacttc taatgtagtc cctatggccg tcggtgaatt
    32761 tgccttacag tctctaaaac aataaggtga aaataaggta aactttgagg tgaacttttt
    32821 caaaaaacat aaaaaaagca cccatgaggt aaactcttga gtgctttgaa acgttgatat
    32881 aattgtattg attaacgttt tgaggcaact gaccttgtca ggttgcagcc acatttgtaa
    32941 gcgactaaag tcgcaacaac tgtgtcaatt gcaccaattt agtaagaaag tataaaaaaa
    33001 gaacaccccg aaaggtgctc tgtataagta tagtaattct ttcgaattaa cgtttactaa
    33061 attgtgatgc tttacgagct ttcttaagac ctggtttctt acgttcaact ttacgtgagt
    33121 cacgtgtaag aagtcctgcg cgtttcaatg aatcgcggaa gtctgggtct acttgaagaa
    33181 gggcacgagc gataccgtga cggatagctc ctgattgacc agcgtatcca ccacctacaa
    33241 cgttaacgaa aacgtcgtat gaacctacag ttgaagtaac tgcgaatggt tggttgatga
    33301 caagacgaag gtcagcgtgt gggatgtact cttcaacatc ttttttgtta acagtgattt
    33361 taccagttcc tggaacaagg cgaacgcgtg caacagcgtt tttacgacgt ccagtacctg
    33421 catattgtgc ttgtgacata ctttatttgt tcctttcctt agataagtcc tgaaatgtca
    33481 agaacttctg gttgttgtgc agcatgagtg tgctcagctc caacaaatac tttcaacttc
    33541 ataccttgag cgcgtccaag tgtattgtgt ggaagcatac ctttaactga tttctcaatc
    33601 aaacgtactg catttttaga acgaagttca cctgcagaga tttgtttcaa tccacctggg
    33661 tggtttgagt gagtgtagta gattttatca gttgcttttt taccagtcaa tttaactttt
    33721 tcagcattga taacaatcac gaagtcacct gtatcagtgt gtggtgtaaa tgttggtttg
    33781 ttttttccgc gaagtacgct agcaactact gcagaaagac gtccaagtgg tacatcagtt
    33841 gcgtcaacta cgtaccattt acgttcaact tggcctggtt tagccataaa tgttgttttg
    33901 ttcatgattt ctcctatata tagttcgatt tttgtttacg gtgatgggtg ttccttccca
    33961 tcgaaaagta tttggaaggt tccggggcct ttcaaatggg gtaaacaata ccgcctacta
    34021 tcataccaaa tttcacccct aaaagtcaat agatatgaaa aatatttttc ggtaacttct
    34081 caaagtaact gaaagttata taatcaagtt aatttgggaa tttacctatt aacttcggta
    34141 gatttttggg aatttttttc cttctttttc cctgtagtta aaatcctttt caaaaaatca
    34201 ccttttcttg atttttaatc ctatttgctg tatgataagg gaaaagaaag gagacagaga
    34261 tatggctttt accaataccc acatgcggtc tgctagtttt ggcattgtta ccagcttgcc
    34321 tgatgacatc attgactctt tttggtatat tatcgaccat ttcttaaaaa atgtctttga
    34381 attggaagaa gaactcgagt ttcaattgct taataaccaa ggaaagatta ccttccactt
    34441 ttcaagtcaa cacctcccta cagccattga ttttgacttt aaccatcctt tcgaccctcg
    34501 ttatccccca agagtactgg ttttagacat ggacggtaga gaaactatcc tcctcccaga
    34561 agaaaatgac ctattttaaa aactctagcc ttcagttgca agtaactgaa aactagagtt
    34621 tttctatttt ttcaaagcat catacaagtt acggatcggt tgttttaata tcggatggat
    34681 aaaatgaggc gcaatttcct gtaaggactc aaggacaaaa aggcgttccg ctatgtaagg
    34741 atgaggcaat atgaggtcgt ctgtataaag gatctggtcc tccacaaaga gcaagtccaa
    34801 atcaatcaaa cgaggtcccc aatgcacttc tctcacccgt cccagctctg actcaatggc
    34861 taacaaggtt tctaacaagt cttgtgctgg tagccaggtt tccacctcaa ccacttgatt
    34921 ggcaaagcta tcctgctcca ctccacccca aggctccgtc gctaagacac tggactcttt
    34981 gagaatatag atgccacgag ctcgcagttt gtcaatggct tgcttcaagt ttgcttgttt
    35041 atctcccata ttgcttccta gggcgataaa ggctcgttgc ttgcggcgat gaatggttac
    35101 cgagcaagta tctagtgaca aatgcaccgg tgcccaaggt tttttcagtt ccaacttcat
    35161 ttcttggaca agaggataag actcaaaggt acgttccacc agtttatagg ctaccgtttc
    35221 aatcaaatct tcactcgttt cctgaaacca agtcgtccac tgctgacaca attctccgta
    35281 atggacagag gctgttaaat ccaagtctgt agctgccttg gtcatatcat aggataggat
    35341 ggctgaaacg acaaatttct gccccaattc tttctcacta ggaaaaagac catgataggc
    35401 aaacatttcc aaatccttaa tctgcagttg atccataatg attcctttct agaaaaatcc
    35461 gcttgaaacg gattcttttt atagccccat taaacgataa gcttggtcgc ggaggtcctt
    35521 atctgtttca aatagaccac gagctactgt cgtcaaggtt gcagtgcctg gttttctaac
    35581 accacgcata ctcatacaca tatgttccgc ctcaatgaca acaaaggctc ctttagcacc
    35641 tagatagtcc atcaaggcat cggccacttc gatattcaaa cgttcttgaa tttgtggttt
    35701 tttcgaataa acttcaaccg tacgggctag cttagacaag cctgccacac gaccatctgg
    35761 aatgtaggca atgtgcgctc taccataaaa tggcaagaag tggtgttcac acatggtatg
    35821 gaaaaagata tccttttcta ccaccatatt atcgtcaata atttcaaagg attttgacaa
    35881 atgttcctct gctgtttgac caagacctga aaaaatctct tgatacatac gggctacacg
    35941 agcaggtgtt tcctgcaagc cctcgcgatt agcgttctct cctacagcct cgataatcat
    36001 ttttacagct gcttcaatct tttgtgtatc cattctcgtt cttcctctcc atcagatagg
    36061 ccctcacttg gctcaagaaa tacaaggaac ctgtgacaat cctaactgtt tgtttctctt
    36121 cttttttatc tgtcaaattc tgctctagaa aatcatgcca atcttggtag ctgagatttc
    36181 tagacttagc tgcctctttc agcacgcttt catccgtcgc ccgactatcc gcaaaatgtg
    36241 ttagagtaag ctcggtatct ggcatagctc ccagcaagtc caacatatcc cccaaggctt
    36301 tggttttgat acaagtgaag aggatttcct tatgataatc cgcaaaacgt tcttgcaagg
    36361 ttaccaacaa ggccttgata gcatggggat tatgggctcc atccaaaatc atcaagggat
    36421 ctcttgacac gatttccaaa cgccctggcc aacttgtttc ttccaaggct tgaccaagaa
    36481 agtcattgct tgctagctct cgaccatctt cttgacaaaa agtatcaagt aaagctatgg
    36541 ccatcccagc attctctatt tggtacaaac caagcaggct agtctggaag cgaccttgtc
    36601 tgacagcact tgtatagtca aagacttccc ctgtcaccac actttcttga tgacgaacct
    36661 gataatctgt cccgtaggca agtctcggcg catctttccc ttccgcaatg cggtcaatca
    36721 cagtcaaggc ttctggagca atacgccctg ttaccaaggg catcccttgt ttgataatac
    36781 ctgccttctg ctctgctatg gcctccaagg tgtcaccaag tagggccaca tgatccaagc
    36841 caatagttgt aattcctgtc aaaatgggct gacagacatt ggtactatcc aaaagtccac
    36901 ccatgccaac ttccatgata gccacatcta cttgctctga ggcaaagtag tcataggcta
    36961 gggctgtgat aatctcaaac tcggttgtgc cctgtaaatt ggcgaccgct tctccctcca
    37021 gcaaagactg atagtctgcc atgagagctt ctagcctcgc ttctgagatc gattccccat
    37081 tgatgctaat ctggtctgtg taatgaatga gatagggcga actaaacacg ccaactctca
    37141 gccctagctt ttctagcatc tttttcaaaa aagcaatagt cgagcccttg ccgttagtcc
    37201 ctccgatatg gagaaccttg agtttaagat ggggattgcc acgcaaagct aacagttcca
    37261 ccattcgttc caagccaaaa tgcggttgat ccgtccggta gttagcaatc cactgattgt
    37321 tttcaatttc tttcatctta tttatattgt tttaaatcta aattttccgc ttcatcagcc
    37381 agacgaatgg cagaggcaat ttcaactgcc atcctgtgac tagctacgtc atgcacgcgc
    37441 accacttcta caccctgtct cgcagcgata ctagttacat gagccgaagc cgtgtcccga
    37501 tttcggaaac caagctctgt ctcaggattg acttcaaacc cactttcttc aaggatattg
    37561 atgacaaatc gcttgcgcga cactccgaga aagattggat agcccttctg atgtagttta
    37621 tccaggtccc gtaaaaggag aagattttct ttcttggtca gaccaaagcc aattcctgga
    37681 tccaacagga tattttctgg tgcaatacca gcttctgccg ctctcgctag tgctcgttca
    37741 aagaaagcca ccatcaagtc ttcgattggc aatgtttcaa agtcagctaa ctctttttct
    37801 gtaaaggttt gaccaaagcc aaaatgaggg aagataagcg aactaggatg ctgaggtcga
    37861 gccataactg ggttaaacat gatgaccact ttcgctccag ctttagcaac cacatgggcc
    37921 attttttcat cacccatgag accagtgata tcattgacta gatcggcacc agcagccaaa
    37981 gcagcctctg ctacttgact cttccaagta tcaatagaga tgaggacatc actttccttg
    38041 cgaatcgctt tgatcactgg aacaacacgc tggatttcct cttctatctc aacatagcta
    38101 cttcccggcc gagtcgattc tccgccgata tcgagcatac tggctccttc tgctatcaat
    38161 ttacgagcct gctggagtgc ctgctcaaga gcaaaaaatt gaccaccgtc cgaaaaggag
    38221 tctggggtta cattgataat tccgcaaata actgtctttg catgattggc tttacttgac
    38281 atatcggtca ctccctcaag gattttcatc atattatttt tctattttac cataaaaaga
    38341 aaaagatgga cacgattgca ttcatctttc cctagtagaa agaggtcggt tcctacataa
    38401 aaacttttaa acagaaattc ctaatgtccg actcataatc accacaagag ccaacaaaca
    38461 gaaagcaatc ccattaacaa tcatgtgaag caagatcgac atttccaaac gttgggtctt
    38521 gtaggccgtc caagatagaa ctgtcgacat acctccataa atcaataaag aaggtaaatt
    38581 acttggttga tgcaataaag caaacacaat cgtaccgact acaaatccca agttctcctt
    38641 gcctcggaaa atctttttag gaacaagccc acggcacaag atttcctcac aaattggagc
    38701 aagcaaggct agcaagaaga agctagaaat cagagaacta ttctgaacca tatcgttaat
    38761 ctgagactgg ttagctgttg tcgtctcatt tgacagttgc aacaagatag aaccaagtat
    38821 atttgaacag ataatgacta aataactcaa gcccaaacgt gccaaatcct tagttctaaa
    38881 aaaagaaaaa ttaaaacttg ccaattgcgt tttacgagct ccaataataa atagcaccag
    38941 aaccacaata gaaataccag taactatcag ccctgactgt agcagggcta cttcttttaa
    39001 agtcaaaata gaggtaacca ctaggggaac ctgatataaa aggacggcaa gtaaaaagac
    39061 caaaatccag cctgcacgat tcaacaattc tttccacata tttttctctt tcatcaccta
    39121 tctcctttgt attaaaaaag ggggaaaatc cccctgggtc attctattat aaggccatgc
    39181 tgatgtagtt aaggataaac aaggcatcca aaatccaaat catggcatga acatctttaa
    39241 cttgaccttt gacaagctta gtcaaagtgt aagtcaagaa accaactgca atcccttgag
    39301 tgatagagta gctgaatccc ataaagatag atgtgaagaa ggcaggaact gcttcagaca
    39361 tatcatccca atagatattt ttcaagctac caagcatcat aatcccaacg ataatcaaga
    39421 ttggagctgt agccgctgtt ggtacgatcg ctagaagtgg gctaaagaag cttgaaatcg
    39481 caaaacagat agctacaacc aaggctgtca aaccagtacg tccacctgca ccgataccag
    39541 cagcagactc aacataagtc gttacgtttg aagtacctgc aatggcaccg actgtcgttc
    39601 caatcaaatc agagtaaaga gccttatcca atttggctga ttggtgattt tcaccatttg
    39661 tcgctacaat accaactttt tcacctgtac cgatcaaggt accaattgtg tcaaaaatat
    39721 ctgtcaatga gaaggcaaga atggccatca gagtttcagg caagcgagct gtatctgaaa
    39781 ccaaagctcc caaaccttct gaaccaagag ctgcaccaaa gattgtcttc aaatcttcaa
    39841 aagctgcacc aacatggtta ttagcaaaat cgatactaga caaatcaacc aaaccaactg
    39901 caatagcaag aacagttgtt gtcaagatag agagaataat tcccccttta atccctttga
    39961 tgacaaagaa gatagtaatg gcaagtcctg caagagccac taaaacagct ggattattaa
    40021 agctgaccaa tcctggaact gctgaagagt ttgctgcaat cgttgcttga gctttgtcag
    40081 ccccttctcc tacaacagta tagttgcctg gatcaatcgt gaatttcaaa agtccagcat
    40141 tcttaatccc tacataggca aggaagacac cgataccagc tgaaatagct gagcgaagag
    40201 cattgggaat cgattcaatg atcattttac gaacatttgt caaggtaata atcaatgaaa
    40261 taatcccaca gatgaagacc atagctaggg cttcttgcca agaataacca agcccgaata
    40321 caactgtaaa ggtaaagaag gcattgagtc ccatacctgg cgcttgggca taaggtaagt
    40381 tagcataaaa agccatcatc aaggtacccg ctactgcacc aataatcgtc gctaggaaga
    40441 cgccctgagc aggcattcct gtttgtgaaa gtatttgtgg gtttacaaag agaatatagc
    40501 tcattgcaaa gaaagttgtt aaaccagcga gaacctctgt acgaacgtct gtaccgttct
    40561 cttttagttt aaataatttg tccatcatca atctcctttt aatttttacg aacaataata
    40621 gaattatatc atttatcatt cactttttca atgtctttgt ttgatttgtt taagaaatta
    40681 atccaacttc attttttgtt tggaatctgc ttttctgcct gctttctgtt ataatagaag
    40741 acatcttatc tgaaaacaca ctagaaaggt ccatatgacg aaaaaaatta ttgcagttga
    40801 cctggatgga accctgctca actcagacag tcaaatttct gactttacca aaaaaaccat
    40861 caaaaaagtt gctgaaaaag gccatcaggt tattattacg acaggtcgcc cttaccgtat
    40921 gtcaaaagat ttttaccgtg aactgggctt agacactcct atgattaact tcaacggatc
    40981 ccttactcat ttaccagacc aagtttggga ttttgaaaag tgtttgactg tagacaaaaa
    41041 atatctgcta gatatggttc aacgttcaga ggacattcaa gccgatttta tcgctggaga
    41101 atatcgtaaa aaattctaca ttacaaatcc caatgaagag attgccaatc ccaaactatt
    41161 tggtgtagaa gctttccagc ctgaagatca attccagcct gaattggtga ccaaggaccc
    41221 taactgtatc ctcttgcaga ccagagccag tgacaaatat gccttggcaa aagacatgaa
    41281 cgccttctac cagcatcaac tttctatcaa tacctgggga ggtccgctca atatccttga
    41341 atgtacccca aaaggtgtca acaaggcctt tgctttggac tacttgctca agataatgaa
    41401 tcgtgacaaa aaagatttga ttgcctttgg agatgaacac aatgataccg aaatgctcgc
    41461 ttttgctggg aaaggttatg ccatgaaaaa tgccaatcca gagctactcc cttatgcaga
    41521 tgagcaaatt tcccttacca acgaccaaga tggggttgcc aaaaccctac aagacttatt
    41581 cttatagcct acactgatac tcaatgagaa tcaaagagca aactaggaag ctagccgtag
    41641 gttgctcaaa gcactgcttt gaggttgtag atgaagctga cgtggtttga agagattttc
    41701 gaagagtatg accagcttgc aagctggtct ttgtgctctt ttcacagtct catcaaccag
    41761 ttaatcgatt gttctacttt ttgtctccaa aaccttggaa aaggctttct tttgtgatat
    41821 acttcacata taaatacaag agagctcgtc acactcgact ctgttgacaa aaaatcaatc
    41881 cagtcccgtt gtccctgttc tcggtcaata tcaaggagga tagctatgaa agctgttgtt
    41941 gtaaatccag aaagcactgg tgttgctatt gaagaaaaag tactccgtcc acttgaaact
    42001 ggggaagcac ttgtagaagt tgaatactgt ggcgtttgcc acaccgacct ccacgttgct
    42061 catggtgact ttggtcaagt cccaggacgt gttcttgggc acgaaggtat cggtatcgtt
    42121 aaagagattg ctccagatgt gaaaagcctt aaagtcggtg accgcgtcag cgttgcttgg
    42181 ttctttgaag gatgtggcac ttgcgaatac tgtacaactg gtcgcgaaac cctttgccgt
    42241 acagtgaaaa atgctggcta ctcagtagac ggtggtatgg ctgaacaatg tatcgtaact
    42301 gctgactatg ctgtcaaagt tcctgacgga cttgatccag cccaagcttc ttctatcaca
    42361 tgtgctggag taacaaccta taaagctatc aaagaagcaa aagttgaacc aggccaatgg
    42421 gttgttcttt acggtgctgg tggacttggt aacctcgctg ttcaatacgc taaaaaagta
    42481 ttcaatgctc atgttatcgc agtcgatatc aacaatgaca aacttaccct tgcaaaagaa
    42541 gtaggcgctg acattgtgat taacggcctc gaagttgaag atgtagctgg actcattaaa
    42601 gaaaaaactg atggaggagc tcattcagct gtcgtaactg ctgtgtctaa agttgccttc
    42661 aaccaggctg ttgactccat tcgtgctggt ggtcgcgtcg tcgctgttgg tcttccttct
    42721 gaaatgatgg aactcagcat cgttaaaaca gtcctcgatg gaatccaagt catcggttct
    42781 cttgtcggaa ctcgtaaaga cttagaagaa gccttccaat ttggtgcaga aggtctggta
    42841 gtcccagttg ttcaaaaacg tccagtagaa gatgctgttg ccattttcga cgaaatggaa
    42901 aaaggccaaa tccaaggacg tatggtactc gacttcaccc actaatttaa tagaaaccta
    42961 ttttaaaagt tggaagcttc ttccaacttt tttatattaa attttaaata agaattcaag
    43021 attactcctc aaaaactcaa catatcaaca tacaaaaata aaaatttttt aattttttat
    43081 gataaatagt tgcttttttt atgaaaacgg tttatactta aacagtctta aagttttctt
    43141 aaatgaaaac taaaacaaaa aaggaggaat gacaataatg agtatcggaa tcattattac
    43201 gagccacggc gaatttgctg cgggtattca tcagtcagga tctatgatct ttggtgaaca
    43261 agaaaaggtt caagttgtga cctttatgcc aaatgaaggt cctgatgatc tatacgctaa
    43321 gtttaataac gctgttgctg catttgacgc agaagatgag gttctagttt tggctgacct
    43381 ttggagtggt tctccattta accaagctag tcgcgtgatg ggagaaaatc ctgagcgtaa
    43441 gtttgccatc atcacaggac ttaacttacc gatgttgatt caagcctaca cagagcgcct
    43501 catggacgct gctgcaggtg tagaaaaagt cgctgctaat atcattaaag aagccaaaga
    43561 tggcatcaaa gctcttccag aagagctaaa tccagttgaa gaagttgcaa gcgctgcagc
    43621 tgctccagtt gcccaaactg ctatcccaga aggaactgtt atcggagacg gtaaattgaa
    43681 aatcaatctt gcccgtcttg acacacgtct acttcacggt caggttgcaa ctgcttggac
    43741 tccagattca aaagcaaatc gtatcatcgt tgcttcagat aacgtggcta aagacgacct
    43801 tcgtaaagaa ttgattaaac aagcagctcc aggtaatgtc aaggctaacg tggttccaat
    43861 tcaaaaactg attgagattt caaaagaccc acgttttgga gaaacacatg cccttatctt
    43921 gtttgaaaca cctcaagatg cccttcgtgc catcgaaggc ggcgtgccaa tcaagactct
    43981 taacgttggt tctatggctc actcaacagg taaaacattg gtcaataccg ttttgtctat
    44041 ggacaaagaa gatgttgcta catttgaaaa aatgcgtgac ttgggtgttg aatttgatgt
    44101 ccgtaaagta ccaaatgatt ctaaaaaaga tttgtttgac ttgattaaca aagccaatgt
    44161 caaataagcc attatttatg aaaggatttt aaacatgtct attatttcta tggttttagt
    44221 agtcgttgta gccttctttg caggtcttga aggcatcctc gaccagttcc aatttcacca
    44281 accacttgta gcctgtaccc ttattgggct tgtaacaggt cacttggaag cagggattat
    44341 cctcggtgga tcgcttcaaa tgattgccct tggttggtca aatatcggtg ctgctatcgc
    44401 tcctgatgct gcacttgctt ctgtcgctgc tgccattatc atggttcttg gtggtgactt
    44461 taccaagact ggtatcggtg ttgcccaagc ggttgctatc cctcttgccg tagctggact
    44521 tttcttgaca atgattgttc gtacaatttc agttggtttg gttcatactg cagatgctgc
    44581 cgctaaaaaa ggtgacttcg gcgctgtgga gcgtgcgcat ttcattgcgc tactcttcca
    44641 aggacttcgt atcgcgcttc ctgcagctct tctccttatg gtaccaactg aaactgtaca
    44701 aagtatcctt agtgccatgc cagactggct caaagatggt atggctatcg gtggtggtat
    44761 ggtcgttgcc gttggttacg ccatggttat caacatgatg gcaactcgtg aagtatggcc
    44821 attcttcgct cttggtttcg ttctcgctgc tgtgtcagat attactctaa tcggattcgg
    44881 tgctatcggt gttgctatcg ctcttatcta ccttcacctt tctaaaactg gtggaaatgg
    44941 tggcggagga gccgcaactt ctaacgaccc aatcggcgat atcctagaag actactaaga
    45001 taagaaagga ctgaaaacat catgactgaa aaacttcaat taactaaatc agatcgtaaa
    45061 aaagtttggt ggcgttcaac cttcttacaa gggtcttgga actttgaacg gatgcaaaac
    45121 ttgggctggg cttatacact cattccagct atcaaaaaac tctatactaa aaaagaagat
    45181 caaatcgctg ctcttgagcg tcaccttgag ttcttcaaca ctcatccata cgtagctgct
    45241 ccagtcatgg gggttactct tgcgcttgaa gaagaacgtg ctaacggtgt ggaaatcgat
    45301 gacgctgcta tccaaggggt taaaatcggt atgatgggac ctcttgctgg tatcggtgac
    45361 ccagtattct ggtttacagt acgcccaatc cttggatctc tcggtgcttc acttgccctt
    45421 actggcaata tcttggggcc actcctcttc tttgttgcat ggaacttgat tcgtatgtca
    45481 ttcttgtggt atgttcaaga gattggatac aaggctggat cagaaatcac taaagatatg
    45541 tctggtggta tccttcaaga tatcactaaa ggagcttcta tccttgggat gttcattctt
    45601 gctgtccttg ttcaacgctg ggtaaatatt aaatttgctt tcgatgtttc taaagttcaa
    45661 ctagatgaaa aggcttatat ccattgggat aaattgccag aagggtctaa aggtatccaa
    45721 gaagcattcg cacaagtagg acaaggattg tctcaaactc ctgaaaaagt tactactttc
    45781 caacaaaact tggatatgtt gattcctgga ttatcaggac tactccttac tttactttgc
    45841 atgtacttac ttaagaaaaa agtatctcca atcactatta tccttgccct cttcgcagtg
    45901 ggtattgtgg cacatgttct tcacatcatg taatcaagca actaaaaagg aaccaggttc
    45961 taaaatctga ttcctttttt ctatgctttt atttagccaa ggctcccatt ggatcccatg
    46021 gtgcaagtac aattggttct gctccatagg cagcttgttc ttctgctgtc agcaattcct
    46081 tacgaacaac gatttggtat gtgtattcgt ccatccaagc gtctgaggca acaaagtaac
    46141 catctgtacc gaccttgtct ccccatgagt tttcaacctt ccacttggtt gatttaccat
    46201 tttcgtccaa gtcaacacct gtcaagacca tggcgtgggt catcaagctt tcgctatagt
    46261 ccaaacgtcc agccttgtct tgagtaagtt taatgtccat gcttgattca aagtcataaa
    46321 catctgtcgc aaggattcca gccttacggt tactgagctg gccgacatca gaaccaaacc
    46381 aaacagtctc acctgcttgc atttgggcaa tcgccaattc tttcaagcgc tccattggaa
    46441 cgttgatgta acgaactgca cggctaccaa ccacattccc caacatctca actgtgtaag
    46501 attttccgta aggtttatca gcagttggag cattgataac agaaacgtag tcttctaaag
    46561 gaagattgac atatttcttg tagaactctt gtggtgtgat tcctttttca cttttgtagt
    46621 tgttatcttt atcgcgataa gcaaagtcaa acttgcgtgg tggaagtcct aatgacatag
    46681 caagaaagtt aaagatttct tgcaagaggt cttctttctt agcttgaaca gtcacttgat
    46741 ctgcaccaga aacaagcaaa tcacgcaaga tttgagcatc ttgacgaagc aatttattaa
    46801 ggatcgcatt tagctcacga ctgctgctag atgaaacaga ctcaggataa actgacttag
    46861 gcacgacacc gtatttttca aagagggaaa cgaccatatc ccattgacca ccatcttgtt
    46921 gaggtgtttg gagtaagaag ctaaccttgc ggctagtcaa ttcttggtct gaagtcgcaa
    46981 tgacttgctc caagaaccag tttgatttct catacttatc ccagaagaaa gtgtgggctt
    47041 gtgacaactc aaagttctcc aatttgtatt gcgagatgag tttgtggcgg aaggtgttga
    47101 gagccgcaaa catccagcaa cgaccagacg ctttctggtt agtgaccttg tccttggtta
    47161 aatccaatga gaaaacaggt gtgttgtcta catggctttg gcgacgttcc agagctgcaa
    47221 aaattccgtt gtggctggca gcattttcaa tcgcttggta ttttacattt gcttcatagt
    47281 tggcaaatag tttatcagta aatgattctt gaatcgcgtt catagattcc tccttttatt
    47341 ctacagtcta ttataactct tttcacaaag gaagcaacta aaaaacataa aaggtaagga
    47401 cattctccct cacctttttc gaatttatac tcttcgaaaa tctcttcaaa ccacgtcaac
    47461 gtcgccttgc cgtactcaag tacagcctgc ggctagtttc ctagtttgct ctttgatttt
    47521 cattgagtat tagtaaccaa aatccgacca catagccagc ccctatgaat atagccatta
    47581 aagctagcat ggaatttagg aaattaaaaa ccaccgcaga tacaaaggtt agcacaaaaa
    47641 cattaaaagc aatggtgtca gaagccaaga ctagaatata gggtgtcaac cgatctaaag
    47701 ttttggaatc taggaaaaat aagtgtttat acatgataat ctcctctatg gctgaaaagc
    47761 aagccttttg tttttttacc ccaagaccct atgtaaaaaa gtcagcaaaa atggtaatgt
    47821 tgcgaaaata ttattgatca catgcaccgc ataggaagga taaatgctct tggtatagcg
    47881 ggtcaaacta gcaaagatga tgccagatgt tgcaaagatg aagatatcta acaaactagg
    47941 caggcttgaa aaatgaggaa gagcaaataa aattgacgga agaagcaaat caaggccaaa
    48001 tctcgaatgc ttaaaaaagg cgtgttgcag taatcctcta tagattagct cttccataag
    48061 tggagtcaga aagaacaaag ttatatagat acctagctca gcaaagttgg tcccactata
    48121 accgatcaat acagcccaac cttcagcagt tgactgaaca tgtttagctg tctgaacgtt
    48181 aaaagagatc tggagcacta ccactaatac tgtcaaaatc gaataccaaa gccatttttt
    48241 tcttggaatg tgaaagagat aaccatgacc tgtcttaacc agaatccaaa tcatgactcc
    48301 gctaaatagc aaactcaaga aattttgaat ccagacgaaa ttgccaatct gggaagaaaa
    48361 ttgccaataa ttttgaataa taagcgtcat ctgagaaaga ccaaatacga aaaataagta
    48421 agagaaaact gcacttattt tgaatagaag ttgatacttt ttcatagaaa tcctccctac
    48481 tatgacctca ccttgtcagg ctctactgct gtaagattaa gaagacagtt tgtttttttt
    48541 aaggctaacc tgactactag ataatagata cattaaggca ttaaagacaa tgaaaatatg
    48601 tccatagaat aaaatcaacc tcgcatccaa accaagataa agtttgatta tcaaaaagat
    48661 gagcaaaaga atttgaaacc ataaggtttt tccaaaaata aatttaaagc gatttcgaat
    48721 atctacttcc ttgattttta ccgccacccc tttattagca agaaggaaaa ctcctgcttc
    48781 aaacaaacca ctgtaaagaa caagccaccc aatagatacg atagagattt gtaaaaatgt
    48841 ccctaaaaga atatccaaca cactactcaa gaaaataaca aaaaataatc tgtatttcat
    48901 attaaatacc tccattcatt tatttcacta acaatttaat agagccttct actcaaatat
    48961 cctgtcagaa aaggatagaa agctactttt tataatactt caagccccac atgagcagaa
    49021 gcgtgataaa caagcagaga atacacctat ataagcgatt agttgttgat agaattctgt
    49081 ttctgaaata cctctataca aacaaatgac aaacataaaa tctgccaagc cgataaacat
    49141 aagttgattg gttctaggac taaccaaatc atcatttact tatatttaag agtatctctt
    49201 ttatgttaat gtatgttagc actgaaaagc aagacaggcc aataatattt aaaatgaaca
    49261 gtaacggggt taagtctcta aaaaaattat ctactgacac tacaagaaat actatacata
    49321 ttatagtcga aactatcttt ttcttatcca taattattta ctcctttcct aacaaatcca
    49381 acttatcaat caagagcgat ttttaacata atgtagcagc acccgttgca actttgacaa
    49441 gtttagtata tcattgtttt ttaaaatttt tcatccaaat cttgaattgt catcgaaacc
    49501 tcctaaattg caaaaacttc attagcccct actttttata atacttcaaa ccccaaatga
    49561 gtagaagcat gatgatcaag caaagaatag caccaatata agcgattagt tgttgataag
    49621 attctcctgc tgtgatacct ctatacaaac aaataataga cataaagcct gtcaagccga
    49681 taaacatgag ttgattggtt ctaggactaa ccaaatcatc atcttcaaac tctcttaatc
    49741 tcatttccct agtaagataa acagtaacca aaatagaagt caagttaata actactaaaa
    49801 gaaattggaa aactgacgaa atagaaatag ataagtagaa acaagcaaag gcaactgacc
    49861 caggaacaat ctcacaaaga atatgattct ttttaatcaa gaaaatcttt catttctttt
    49921 ctttcttttt aattaaagaa aaatagatca taaccgcaat catataggct atggtataaa
    49981 atagattata ccaaatactc tccctaagcg gataaagaaa gatggacatg atcagataca
    50041 gaacgaaaat aatcagtatt tttttcttca taagttttcc tcctaaatgt gcgatttatc
    50101 ttagttgagc aagaacattt acactgctag tatagcactt attttgacct tggatcactc
    50161 aaatcataaa tggtcatcaa aacctcttga attgtaaaaa ttaaaaaagc aagcatgaaa
    50221 aacatacttt cctctttata ttgtattgat accaacttgt ttgtagactt ttcatcctgc
    50281 tatcacatat cattttgaca ggcgaaacaa tattaaagaa actcccctgt aaattaagct
    50341 agcaaataca ggggagaaat ttatttttta gagagtacta tccgtatcct ttttggaaga
    50401 ttttgaaaat atttttctaa ttaagtcatc catataagga ccaaatatac caactactaa
    50461 accaataata aaacttttaa aatccataat taccaccaac atgttgctgc ataggctaca
    50521 cctccaagta tagctccacc tgcagcacca gttacaccta ttcctatagc aaatggtccc
    50581 aatagaaatg tcaaaccgtt gttgcacacc catcaattgc gccatatgca acccctgctg
    50641 cacaactaat ttttcttccc caatcaatat ctccaccttc aacgcaagca agcatttcat
    50701 tatccataac agaaaattgt gacatcattt ttgtattcat atagtatgtc acttttcagt
    50761 tacggaacaa gtttaatata aaaattatca aaaaaacata ggcaataaag agaaaaatta
    50821 atttatcata gattagaaat aatatgacaa aacaattcaa tgatgttaat tcaatagtct
    50881 tttgtttttt atcagagata cttatggata gataaataag ataggtttga aaagcgaaga
    50941 gaataataaa gaatatagcc ttcataaaat ttagctttca tttttatgat gtagcggtat
    51001 aggctaaata tccacaaacc actgctcctc caattcctcc tattgcagcg ccccatggtc
    51061 ctagaatttt cccatatttc actccacccg ctgcacaacc taaagcagca actacagctg
    51121 ctcctccaac acctgctttg gcaaaatctc cccaattgca tccgccacct tcaacgcaag
    51181 caagcatttc attatccata acagaaaatt gtgatatcat ttttgtatcc atgacaaata
    51241 ctcctttttt aaaaaactaa aataaatcag aatagaatcc tcataatttt actataagtc
    51301 ttaccaactt agtcccaatt tatcaccaac catacctcct aagcatgtta atccaccccc
    51361 aattgcacca atgtgtgctc caacaaatgc accagcaagt ccagctactc ctaaagtggc
    51421 caaacctgct ccagttccac cagttataat tcccgtagtg actcctgtaa tcagtgcatt
    51481 ttgacaatca gtggagctat accccccttc aactttcgca agcatttcag tatccataac
    51541 ctctaactgt gacaacattt ttgtattcat gatgaatacc tcctttttat tttcaatttg
    51601 ttaccaaagt cttaaattca ataaacaaat agattttttt tagtatcttt ttgattttct
    51661 taaaaaagta tatacgtcta ctatcttctt aaaggtagca gtacctattt tttagtctaa
    51721 gatttcaata atcttgagta tctaaaatat cttaatttcg ttattctcct tgcaataaaa
    51781 agttttacta tactatttat taacttgcag aaagcaaaaa atattagtaa ataatagttt
    51841 atagttaagt tttttattcc taccaatcca tcaactaagt aaagcatcaa cgattacata
    51901 aacgattgat aatataatta aaattttgct aactatctta ttctcatgat tcttagataa
    51961 ctttgatatt ttgtaagtaa gtaaataaga cagtaaatta atagcgataa taatactata
    52021 tttaagaatc ataatcttac aaagaggaca taattcctga acctacacaa ataagtgttg
    52081 ctgctccccc agttatcgga ccagtcgcag cagctaatag tactgctcca atacaaccac
    52141 cgattgcaga tcctaaattg cctcttcctc cactaactat ttcgagttct tcattatcca
    52201 taacagaaaa ttgttccatc atttttgtat tcatgacaaa tactcctttt ttcttttttt
    52261 atttttgtct tgttgtaact ttgataagtt tagtatatca tcgtttttta aaatttttca
    52321 tccagatctt gaattgtcat cgaaacgtct tgaattaggt tttttatttc aagccacctc
    52381 taaatgttta aaaaaaataa tttctaatca cttttttacc attcaggaag ttttaatgac
    52441 tattcaagat ttcataaaat atgaacttag ttttatgaca taatagacct atccactata
    52501 tgaaaggaat tgccaatgac ttcttataaa cgtacatttg ttcctcaaat agatgcgaga
    52561 gactgtggtg tcgctgcctt agcctcgatt gctaaattct atggttcaga tttttctcta
    52621 gctcacttga gagaacttgc aaagaccaat aaagaaggga cgactgctct tggcattgta
    52681 aaagccgctg atgaaatggg ctttgaaaca agacctgttc aagcagataa aacgctcttt
    52741 gacatgagtg atgtccccta tccatttatc gttcacgtta acaaagaagg aaaactccaa
    52801 cattactatg ttgtctatca aacaaagaaa gactatctga ttattggtga tcctgaccct
    52861 tctgtaaaaa tcactaaaat gtcaaaagaa cgctttttct atgaatggac tggagtagct
    52921 atttttctag ctaccaaacc cagctatcaa ccccataaag ataaaaagaa tggtctacta
    52981 agcaagcttc cttcctctga ttttcaaaca aaaatctctc attgcttaca ttgttctctc
    53041 aagcttattg gtcactatta tcaatatagg tggttcttac tatctccaag gaatcttgga
    53101 tgaatacatt ccaaatcaga tgaaatcaac tttaggaatc atctcagttg gtctggttat
    53161 cacctatatc ctccaacaag tcatgagctt ctccagagat tatctcctaa ccgttctgag
    53221 tcagagatta agtattgatg tgattttatc ctatattcgc catatttttg aacttcccat
    53281 gtctttcttt gcgacacgtc gtacaggaga aatcatttca cgattcacag atgctaactc
    53341 tattatagat gccttggctt ctaccattct ttctcttttt ctggatgttt ctattctgat
    53401 tcttgtagga ggcgtcttac tggcacaaaa ccctaatctc ttccttcttt ctcttatttc
    53461 cattcctata tacatgttca tcatcttttc ttttatgaaa cctttcgaaa aaatgaacca
    53521 tgatgtcatg caaagtaatt ctatggttag ctctgccatt atcgaagata tcaacgggat
    53581 tgaaactata aagtcgctca cgagtgaaga aaatcgctat caaaatatag acagcgaatt
    53641 tgtagattat ttggaaaaat cctttaagct cagtaaatat tctattttac aaacgagttt
    53701 aaagcaggga acaaaattag ttctgaatat ccttatccta tggtttggcg ctcaattagt
    53761 catgtcgagt aaaatttcta tcggtcagct gattaccttt aacacacttt tttcttactt
    53821 tacaactcct atggaaaata ttatcaacct ccaaaccaaa ctccaatctg cgaaggtcgc
    53881 taataaccgt ttgaacgaag tctatctagt cgaatctgaa tttcaagttc aagaaaaccc
    53941 tgtccattca cattttttga tgggcgatat tgaatttgat gacctttctt ataagtatgg
    54001 ttttggacga gataccttaa cagatattaa tctcacgatt aaacaaggag ataaggttag
    54061 cctagttgga gttagtggtt ctggtaaaac aactttagcc aaaatgattg tcaatttctt
    54121 tgaaccctac aaaggacata tttctatcaa tcatcaggat attaaaaaca ttgataaaaa
    54181 agtcttgcgc cgtcatatta attacctacc acaacaagcc tatatcttta atggctctat
    54241 cttggaaaac ttaactttgg gcggtaatca tatgattagc caagaagata ttctaagagc
    54301 ttgtgaatta gctgaaattc gtcaagacat tgaaagaatg cctatgggct atcaaactca
    54361 gctctctgat ggagctggtc tatcaggagg acaaaagcaa cgaatagccc tcgctcgtgc
    54421 tcttttaact aaagctcctg ttttaatact agacgaagct actagcggtc ttgatgtctt
    54481 gactgagaaa aaggttatag ataatcttat gtctctaact gataaaacca ttctctttgt
    54541 agcccatcgt ctcagtatag ccgaacgaac caaccgtgtc attgttcttg accaggggaa
    54601 aatcattgaa gttggtagtc accaagagtt aatgcaggcg caaggtttct accatcatct
    54661 attcaataaa taaggagaat gtcatgaatc ctaatctttt tagaagcgtc gagttttatc
    54721 agagacgtta ccataactat gcgacagtgt tcattatacc tctttcatta ctatttactt
    54781 tcatcttgat tttctccctt gttgccacaa aagaaattac tgttacttcc caaggagaaa
    54841 tcgcccctac aagtgtcatt gcctccattc agtcaaccag tgataatcct atcctagcta
    54901 atcatttagt ggcaaatcaa gtagttgaaa aaggggactt actcatcaaa tactctgaaa
    54961 caatggaaga aagtcagaaa actgccttag caactcaatt acaaagactt gagaagcaaa
    55021 aagaaggact tggaattttg aaacaaagct tagaaaaagc gactgatctt ttttctggcg
    55081 aggatgaatt tggctaccat aataccttta tgaattttac taaacaatcc catgatattg
    55141 aactgggtat cacaaagact aacaccgaag tttcaaatca agctaatctt tccaatagca
    55201 gttcatcagc tattgaacaa gaaattacaa aagttcaaca acaaattgga gaatatcaag
    55261 agttgagaga tgctatcata aataacagag cacgcttacc aactggcaat ccgcaccagt
    55321 caattttgaa tcgttatctt gtagcctcac aaggacaaac acaaggaact gcagaggagc
    55381 catttttatc tcaaattaat caaagtattg caggtcttga atcatctatc gcaagcctca
    55441 aaattcagca agctggtatc ggaagtgtag caacttatga taacagttta gcaaccaaaa
    55501 ttgaagtact ccgcactcag tttttacaga cagcctcaca gcaacaacta actgtggaga
    55561 atcaattaac agaattaaaa gtacaactag atcaagccac acagcgtttg gaaaacaata
    55621 ccttaacctc cccaagtaaa ggtatcgttc atctgaacag cgaatttgaa ggtaaaaata
    55681 gaattccaac tggtacagaa attgctcaaa tattccctgt catcacagat acaagagaag
    55741 tactaatcac ttactacgta tcttctgact atctacctct actagataaa ggacaaactg
    55801 taagattaaa actggagaag attggaaatc acggcaccac catcatcggc caacttcaga
    55861 caattgatca aactcctacc agaacagagc aaggaaatct ctttaaatta accgctcttg
    55921 caaaactatc taacgaggat agtaaactca tccaatatgg cttacaaggt cgcgtcacta
    55981 gtgtaactac aaagaaaaca tattttgatt atttcaaaga taaaatttta acccattctg
    56041 attaattttc agataacact ctataactat ttattatctt atcaaaaagg agaatcataa
    56101 catggataag aaacaaaacc taacttcatt tcaagaacta acaactaccg aactcaacca
    56161 aattacaggt ggaggattgt gggaagattt attatataac attaatagat atgctcatta
    56221 catcacataa gaacttcatc atccaataca actataaaaa aataagaccg agaaacaagt
    56281 actctcggtc ttatttttca tcattctgta tgtatcacag taagtacctg acgaaagact
    56341 tgattttgac aggtggtatt tagactggta ttaggatggc tttccacaat cttcatgacg
    56401 gtatagagac caactcctct ctcctcccct ttagaactgg ctccaaagga gaagatttca
    56461 gaaatatcga tgccctcttc tttgatggag ttttcgatga taaaggtctc ctgtgctcca
    56521 ttttttaaaa aggcgattga aacatgaggt tgactagctt ccacactggc ttcaatagca
    56581 ttgtcacaaa ggatagacac aatggttaga aaatcaagta gactcatccc ctcgacctga
    56641 atctcctcag gaacttcgac attaaagaca atgttcttat ctctggcttt taaaaatttc
    56701 cctgctagaa gacttttgag ggctttatca cgaatattta ccaatctgcc caggtcatat
    56761 ttattgttct gcaatttctg actggaatcc tttaagacgg agccatagac ctcttttatc
    56821 tgctccatat cctcctcttc aatgcccaga cgtaagctag tcaagaggtt ggtataatca
    56881 tgacgaaagc tccgtacttc cttgtaaagc tcctctatat gccgactata gcgttccata
    56941 tctctatagc gcagggcctg ctcttgttcc aatctctcat agagtttttc cttcaaatag
    57001 gtatccaatt tcttgataac ccccataaaa aagagtaggt aaaagactag gatgagatgg
    57061 cgaacagtct ttgattgaat actttgttca tattcaaaaa aagacagact ttccatgact
    57121 agatagtagc cacccattat ccagttaatc tgagtcaggg acttttgaaa ggctttatcg
    57181 agaatctcct ttctcaagct agtaaaatcg tagtccaacc atttcaaaaa agctagagaa
    57241 atgaagaaat tgaaaattat tatacataac ccagtaaatg agtagccatc atatacttgc
    57301 ccttgtccca aaaatggaag cacaaaatag gagactcctc tataaaagag attcaccaat
    57361 atcattggaa agagaccata aaagaaaagg agttttttag gaagccctct caataataag
    57421 aaagataagc ctatgccgta caagggttcc ataaaataag ataggtaaac atttcctact
    57481 atatagctaa tcatcacaaa aacaaaggcc aacagtatct taaaaagaaa ggccttaaaa
    57541 atcctctcga aagtaagatc aattccatcc accttaaaga agatgacaat ttctagtcca
    57601 ttagtaacaa gtgtatacaa caatatccaa gcaatgttca taaattctcc tagctcagtg
    57661 taatttattg atggcctcag acacttccct gaccttataa cgggcgatta gacaacttcc
    57721 accattggga aagaaaagca gtttttcttt cttatccaaa tgcaccacat ttgcaggatt
    57781 gatgagaaaa gagcggtggc actgcaagag acggggctcc tgcttgaaaa cctcctctaa
    57841 actcgctgta aattccagcc tgtctgtctt ggtatagaga ataacacgat gggctctggg
    57901 cgacgtttcg agatagtaaa cctctttaaa aggatactga aattgggcaa attttgattt
    57961 aaagtaaaag caatcttccg ccagactttt actatcttga ctattggcat agaggagggc
    58021 tgtctcgatc cgagattcaa actcctctgc tgacaaggcc ttatcaatgt agtccaaagc
    58081 agacacttgg tagcgaaaag acaggggcat aaactccgag tgagtcgtca caaagacaat
    58141 cagggcataa ggatcccgat cccgaatctt tctagccact tccagtccct tcatctcttc
    58201 atttcgaatc tcaatatcca aaaagaatag ctgatgggcc cccttctcat gcacttcagc
    58261 cagcagttgg tccggcttgc caaatacctc aaaagagcta ggaatgatat gatgtgcttt
    58321 caaaagtttc tcaatcgtcg tttcaattct agtctattgg gaaaaatcat cctctaaaac
    58381 aaatattctc atcttcttac tctccctctt tcaaccattt ttgacgaatt tctctatagc
    58441 gacgtctggc atacttgaca gcgtattgac cttcttctcc gagaaaaagg attctttctt
    58501 gaaaatcaat cgattttaat ttatcaagat taaccaaaca atttcgatga catctcatca
    58561 aggtttcccc acattggttc tcaagattac ttaaattttg aagcatatta aaactagctt
    58621 cttctgtaac aatctgtacg gtatgggctt tagttggatg tgtttggata tagtagatat
    58681 cgtcgatgtt tactttatag actgttttct gcgtctgaat aatcatatat ttcattggat
    58741 tctcctccta agaaaagaat aacagaaaag gtctagccca agcacaccca atcctaaaca
    58801 gtctttgaaa actcctaaaa ggattatttt ctacaacatc atgatgagct tacaactatt
    58861 ttatcataaa attcactcag cgcaattcaa gacatttcaa tgacaattaa agatttgaat
    58921 aaaaaaaaag aattaaaagt gataaactaa cagtatcaaa acacagttgc cagaagtaag
    58981 actggcaccc agattaaagg aggcattccc atgacagata cagaccccat caaaagagct
    59041 catactttga ttactgactt aaacaaagcc taccaagcat gcaaacaggc aagcgctgac
    59101 gacgtccgct ttcaggagca attaaactct attcttggtt ttctagccaa ggctgaaaca
    59161 gtggataatc gattcttgat tgaactagaa aaattttacc agacttccag tcttctcatg
    59221 ggactcagcg ctcttgatcc agatgctcca actcgcgccg cttggcgggc ctatgaccgc
    59281 ttccactttg accaagtcaa gaccaagtta atactcaatg aaaatcaaag agcaaactag
    59341 gaagctagcc gcaagctgta cttgagtacg gtaagacgac gctgacgtgg tttgaagaga
    59401 ttttcgaaga gtataagtct ctacggacca accattatcc tgtagtaaca aaaaagaagt
    59461 tgagacagac tgaactcaac ttctttttta gtgtcgtatc agcaatgtta gtcctgcatc
    59521 tgacgtttta cctgataagg caaatacaag actagtaaaa ccaaaccagc tcctagtaag
    59581 gctagaaggg ctagtttttc ttggaaggta atcaacccaa caactaattc cacaagtaaa
    59641 acaaaactgg tcaatcctcg aactacctcc tgtaagcctt tttccttttg ccccttgtcc
    59701 agcggaaaga gttgggtcaa atactggtag tcaaaggcat gatagagggc cagcaactgg
    59761 aagagcaaga ggtagttaaa gagaactacc actgctgtcg caatccaagc ttgctcgata
    59821 aaaacctgcg ccagtacgga aagtaagaga agacgaagac tgagagcaaa gaggtcgcca
    59881 tttcgcagat aagaacgcag atagagattt tgccaaatct tcccaggcac cttctgaaca
    59941 gcctttaaga taaagtccag ataggcacga cgcttaacgc tgtttgaaat tcccttgacc
    60001 tgcgtaaaga gggcaaagaa acgaagcaag acttgcttac gcttgctttc ttgggaaatg
    60061 acatagtccc aatccagtcc agtttcagtg aaaaatttgc tggccttttg acgaaagtgg
    60121 aaatattttc ctacccccaa taaaagcaca tagagcagaa aaactggcaa gccataaccc
    60181 attgctaaaa ataaaggcgc aaataacagc aagaaaaggg tctgtacaaa gagccaaaag
    60241 actagggaaa tgccagtttg acgcttgaga tggagcttga tttcctcttc tccaactaag
    60301 agaaagagct tgtctggagc ctccatatag gtggcaattc ctccccaaag taaaagtaaa
    60361 acagacgtaa ttcctacaaa caaaaggata ggccaatgat tttcaggaaa atgttgtaag
    60421 agttgactgt actggtaggc tagaaagccc aacaggacaa gcaggaacaa gacaaagtgg
    60481 tcattgagca catagcgcag ataaccaaga cactccttac gaaaggcctg ctttctcttt
    60541 aaaaacaagt ctttcatagg tcctcctctt ttgtcagagc caagtaaata tcattcaaac
    60601 tagcctcagg catatcaaag gcttcgcgta gttgcaggag attgcctttg gcacgcacct
    60661 ctcccttgtg aagaatgaca aaggcatcac acatcttctc cgccgaatcc agcacgtggg
    60721 tactcatgag aatagacttg cccttttgct tctccacttc caaaagctga atcaaatcag
    60781 aaatagccag cggatcaaga ccaaggaaag gctcatccac gatgaaaaga cttggatccg
    60841 ccacaaaagc acagataatc atgaccttct gcttcatccc ttttgaaaaa tgaacaggga
    60901 accagtctaa tttctgttcc aaacggaaca tttttaacaa gggctctact cgttcgaaag
    60961 ccactttttg ctcaataccg taagccatag caaccgtttc gatatgctct ctgagggtca
    61021 attcctcata cagactaggc gtctcaggaa tgtagccaat ctgcttgcgg tagctagtcg
    61081 catctccttg cagagtcagg ccattgatat tgatggagcc actataaggt gccaacagac
    61141 cgataatctc attgatcgtc gttgatttcc cagcaccatt gagaccaatc aaaccgacca
    61201 actgcccact ttcaacagta aaggacacat ctttcaaaac aggaacatga acatagccac
    61261 ctgtcaggtt tttaatttct aacatatttt ctccaaatct ggtataatgt agctatatta
    61321 tatcaaaatt cagtacagta gaggtagatt ttatgtcaga ttgcattttt tgtaaaatca
    61381 tcgcagggga aattcctgct tcaaaagtat atgaagatga gcaggtcctt gcctttcttg
    61441 atatctctca agtaacacta ggacacacct tggtcgtgcc aaaagaacac tatcgcaatc
    61501 ttttggagat ggatgctacg agcgccagcc aactctttgc ccaagtacca aaagtagctc
    61561 aaaaagtcat gaaagtcact aaggctgctg gtatgaatat catttccaac tgtgaagaag
    61621 tcgctggtca aacagttttt catactcacg ttcaccttgt acctcgctac agtgctgacg
    61681 atgacctcaa gattgatttt atcgcccacg aaccagactt tgacaaactt gctcaagtcg
    61741 ctgaaaccat caaaaacgct taaggagttg ctatgaaatt atccaaccta ctgctatttg
    61801 caggagctgc agccggaagt tatctggtca caaaaaatcg ccaaaccatc acagatgaag
    61861 tcttgaatac cactgaccgc gttcaagcta tcaaggacga tgtggatatt atccaaaaca
    61921 gcctgcaaat cattgaccag caaaaagaac ttatcaagga ataccaagaa gacttgactt
    61981 acaagtttaa ggtcttggaa aaggatatcc agactagact agctgtgata aaagaaatgc
    62041 agggaactga agataagtaa aaagagcccg acggctcttt tttaaaacgt aaacaagtta
    62101 tagtgaattg aatttagaat agcacatcat agtttctaaa gcattgttag agattacttt
    62161 aaaatcctct tatcaatttg ttcatattct atttcaatct actatatata tcccatcaac
    62221 tatgcatcat aatttaggta actcatactc aataaaaatc aaaaagcaaa ctagaaagct
    62281 aggcacagac tgctcaaaac accgttttaa ggttgtggat agaactgacg aagtcagtaa
    62341 ccatacccat gacaagccga cgctgacgtg gtttgaagaa atttttgaag agtatcattc
    62401 accatttcac aactaaatcg aagactttct gccgtaatga aaacacctga aacagcttgg
    62461 tttcggctat ccggaaactt taagacttag gttcaaagtt taggtatgga acttcgaagg
    62521 aggtcgctac cgtccgtcat tacttaggaa agtcttaaaa aatctataaa gtaaaaagag
    62581 cccgacagct ctttttgttt atactcaatg aaaatcaaaa agcaaactag gaaactagcc
    62641 acgggctgct caaaacactg ttttgaggtt gtagatacga ctgacgaagt cagtcacata
    62701 tatacggcaa ggcaacgctg acgtggtttg aagagatttt cgaagagtat tattctccat
    62761 caaaggcatc tttaatatgg tcaaagaagc cttttttctt tggatttact ttcaagtcac
    62821 cagcagccgc gaattctttc aaggctactt tttggcggtc gttcaagcct gtcggtgtta
    62881 cgacattaac agtaacgtat tggtcaccaa ctgcaccgcc acgaaggctc ggtgccccct
    62941 tactacgtag gcggaacttc ttaccagtct gagttccctc tggaataacc aattcaacat
    63001 caccgtgaac agttggaata tctactgtat caccaagagc cgcttggaca aagttgaggt
    63061 tgagattgta gaagatagtc gttccttcac gttcaaactt gtcgctagct tccacagaaa
    63121 ctactacata caagtcacca taaggtccac cgttaaagcc tgcttcacct tgaccagcga
    63181 ggcgaatttg ttgacctgtt tccacaccag cagggatttt cacatgtacg ctatgagctt
    63241 gtttctcatg acctgttcca tgacaggttg tacatggata tttgatttct tttcctcgac
    63301 cgtgacagac atcacaggtt acttggcgac gcatcatacc aagaggagtc tgcgtatcga
    63361 cgttaatgac accagcgcca tgacagcgtc cacaagtgac tggacttgtc cctggcttag
    63421 caccagatcc attacatgta cgacagccag cttcacgatg atacttaact tccttctcag
    63481 ttccgaagat agcttcttca aaggtcaaat tgacacgata ctggagatca tctccttggc
    63541 gaggagcgtt tggattgcgc gaagaaccgc ctccgccgaa gaaacttgag aaaatatcct
    63601 caaaaccacc gaagccacct gccccattga aaccgccgaa accaccagct ccaccaaaac
    63661 caccattggc gcctgcagca ccatactggt cataggcagc acgtttttgg tcgtcactca
    63721 aagtctcata ggcttcttga acttccttgt acttgtcctc agcaccaggc tccttgttga
    63781 tatctgggtg atattttttg gaaagcttac gataagcctt tttgatttcg tctgccgaag
    63841 cgtttttgga tacccccaga cgatcataaa attcagtatt gttcataatt caagatacaa
    63901 agggcgtcaa acggacacag ccatctagga gttttgacga cggacgctta cgtcctagaa
    63961 aaaactatct ttttggcaca gtccatagcc cgtgttcagt tacgaacacc cttattcctt
    64021 tctattgatg ttctgaatcg aaccaccatt taggtcgggt tcaattcctt tcttttatat
    64081 ttagtaagaa attctgaaac ccgtgttcag ttacgaacac tctttgttcc tttctattga
    64141 tgagacaaaa cccaaacaaa tgagattccg tcccttttta tcgaaaaaca gaggctgggt
    64201 tgcaacctct gcaaataagt aaattaactt tattttgatt ttaaatatcc tataagtaca
    64261 gaaatattta tatatttttg tctcttctta gtatttgcct atataattcc aattgatcat
    64321 aagaaataca actactgtcc aaatcatacc aattatgaac ggtattacaa atttatatgt
    64381 ttgtatttct aatgatatca tagctgatac catcgctgat acaaatgcag acaacaatac
    64441 tgaagtaaca aaattcctta ccgcttcatc atttttgaca caactatcat gctcagctaa
    64501 tataatttct ctatatatag tcaaacattc tactggaata ttatctataa aaccttttgc
    64561 tgcttcatag ttgtcagctt gattacaaaa atcattataa acttttcgtg tattttttag
    64621 atactcatca tccaatacac tcatcttatt tttccgtaaa ctctccgtct acgacgtcat
    64681 cgcctgcgtt tcctgttgct tgtgcgcctt ctgctccttc ttgagcttgt tgcgctgctg
    64741 cggcttgttc gtagagtttc acagcaaggc cttgagcttt ttcgttcaac gcttcaagtt
    64801 tcgctttcat gtcgtccaag ttgttgtctt cttgagcttt cttaaggtca tcaagggcag
    64861 cttgggcagc gtcacgttct gcgtcgaagc ctttaccttc agtttccttg attgtctttt
    64921 cagtcgcaaa gattgcttgg tctacttcat tacgaaggtc tacttcttct ttacgtttct
    64981 tatcggcttc agcgtttgct tctgcatctt tcatcatgcg gtcgatttct tcgtcagtca
    65041 aacctgagtt cgattggatg acaatagttt gttctttttg agttccaagg tctttggcct
    65101 taacagacac gataccgttc ttgtcgatgt caaatgttac ttcgatttga ggaattccac
    65161 gaggtgcagc tgggatatca gtcaattgga agcgtccaag agtcttgtta tctgctgcca
    65221 ttgggcgttc accttgaaga acgtggatat caacggctgg ttggttgtct gctgctgttg
    65281 agaagacttg tgatttagat gttgggattg tagtgttgcg atcgataagt tttgtaaata
    65341 ctccacccat tgtttcgata ccaagtgaca atggcgttac atcaagaagg acaacgtcct
    65401 tgacatcacc agtaatcaca ccaccttgga tagccgcacc catagcaact acttcatcag
    65461 ggtttactga tttgtttggt tctttaccag tttcagcttt aacagcttca acaacggcag
    65521 ggatacgagt tgaaccacca acaaggataa cttcgtcaat ttctgacaag ctcaaacctg
    65581 catctgaaag ggcttgacga actggaactt ttgtacgttc aacaaggtca cgagtcaaat
    65641 cgtcaaattt cgcacgagtc aaagtcattt ccaagtgaag aggtccagcc tcacctgcag
    65701 tgataaatgg caagctgatt tgtgttgaag ttacaccaga aaggtctttc ttcgcttttt
    65761 cagccgcatc tttcaaacgt tgcattgcca tcttgtcagt agacaagtcg ataccgtttt
    65821 ctttcttgaa ttctgctacc aagtggtcaa tgattttttg gtcaaagtcg tcaccaccaa
    65881 gtttgttgtc ccctgcagtt gacaatacgt cgaagacacc gtcacccaat tcaaggatag
    65941 agacgtcgaa tgtaccacca ccaaggtcaa ataccaagat tttttcttct ttgtcagtct
    66001 tgtccaaacc ataagcaaga gctgctgcag ttggttcgtt aacaatacgt tctacttcaa
    66061 gaccagcaat tttaccagcg tcttttgttg cttgacgttg agcgtcgttg aagtaagccg
    66121 gaactgtgat aacagctttg gttactttct caccaaggta gtcttcagcg tagcctttca
    66181 agtattgaag gatcatagct gagatttctt gtggagtgta ttcttttcca tttgcagaaa
    66241 ctttttcaga agttcccatc ttagatttga tagagataac tgtatctggg tttgtgactg
    66301 cttgacgttt tgcagcatca ccaacgatga tttctccgtt tttgaatgag actacagatg
    66361 gagttgtgcg gttcccttct gggtttgcga tgattttgct ttcagttcct tcaagaactg
    66421 caactgctga gtttgttgta cctaagtcaa taccgataat tttagacatg tgtttttctc
    66481 cttgttagtt aattttctat ttttcttttt gatactcttc ttaagtggcg acgccgtcag
    66541 agcttgactt cgtcaatctc tttgactaaa ctttgagcct aaggtctcaa aatttgcgca
    66601 aatagcacca cggcgaagag tatcgtcttt ggttcgcttc gctcactatt acaaagccaa
    66661 acatatttta tctttcttca tagtttattg tcgtttcgga caagttttct attatgtaaa
    66721 ttgcgacacg aggagtcgaa atcgatttta tttcgacgac gagttagtaa ggaagctagg
    66781 caaacgtcat agcgattgcc gttttctgac gagttgcttt agctaccgtc agaattgccg
    66841 aatcgaacac gccctaagct ctgagtaaaa aagatagatt ttcttgtgtt catcgaacac
    66901 ttcgtcaatc tcctattttt actgcgagct ttttacgagc tttgtatctt agttatacac
    66961 cactaccatt gctgggcgta ggatgcggtc atggagtttg tagccttttt gaaagacttg
    67021 ggcgatggta tctactgggt gttcatcgtc tgctgggaga gtttggatgg ccatatggta
    67081 gttatggtca aattcgccat ctgctgcgat ttcttcaatt ccttcttctt tcaaagcgtg
    67141 aatcaagctt tcttgcacca tcgccaagcc cttcttcaca tcatctgtca aaccttcaac
    67201 tgcaagtgca cgctcaaggt tgtcaagaga tggtaagatt gcttttgcca agtcctggct
    67261 acgataacgt tgcaagtttt gacgttcttc attggcacgg cgttggatat tttgcatttc
    67321 tgcatgagcg cgaagatatt tgttttcgaa ctcatctgca cgttcatttg ccaagtccaa
    67381 ctcagacttt tcaggagttg tttcttcagc tgtttccaca acttcctctt cttgaacttc
    67441 ttctacttct tcatttttta tatcttgggc catgttcgcc tcctttaatg atttcaatct
    67501 taatgtactt cgtaatgatt actgctgagg tagcggtaaa aatctgtcaa cttcatggtc
    67561 aaaacacggt tgaccacatt gacttgattg attagctgtt ggtaatccag attaactgga
    67621 ccgataatgg ctagaattcc aactccccga taaggaatga ggaacttact actaatcacc
    67681 gctaggtcag ctaaacagga ctcttgaccg tctgcaacac gaacattttg catctgatcc
    67741 tcacgcaacc cctcacgaat ctccaaggcc accttttgcg gttggtcaaa gaactgatag
    67801 gctgctagat tggcaaaatt caagagatgg accttgcccg ccatcacaat gttttcgttg
    67861 aacatttcct taaagatgtg ttcaaagaga tcgatgacat tatccgttgt tgtaaagtaa
    67921 cgctggataa tctgcggaat ctccgtccga atcttgtagt gaatatctaa aacggtgtga
    67981 ccgaggaaac gttcctgaat gatgctcttc agtttcagca aatcctcctg caagaagttc
    68041 cttggaatca gaaactgact agtaaccgtt cgcgactcgt ctagggtaaa taccgccaag
    68101 gctgtatgtt gccccaaaac aacgatatca aaggctgtca aacgttgcct gctcggctca
    68161 acatccagtg ccactaccgt acagccactc aggtctgtta gcaagttagc agcctcttgc
    68221 agaatatcct ccaatttgaa gaattcctga tcaaaggctt tgacaatctc atatacctca
    68281 ttttcagcca gtcggtcaaa atccagtgag tgtttcacat agtactgaaa accagcaaca
    68341 cttggcatcc gaccgcttga agtatgagcc ttctcaagca acccttgttt ttctagttcc
    68401 gccatgtcat tacgaatggt tgcactgcta gagttaatag actcttgcaa ggtttttgat
    68461 ccgacaggtt cgtgcgtttt ggtaaagatg tcaataatca gatttaaaat atcctgctga
    68521 cgctctgtaa ccatctcatc actcctctct gtctgatcaa ttagcactca atgcatccaa
    68581 gtgctaactc atgattctat tatacaccct tagaagagaa tgtcaagaca aaaactcaaa
    68641 aaattagcac tcttttatca agagtgctaa aaatcaatct gaagacctag aaccttgcta
    68701 ttcatctact cggtatttcc tttttagtct gaaataacca tgaattagat aagaaatcag
    68761 aaaagcatat aaaacaaaaa ataagaaaga aagacataga aagatcctct ctaaacaaac
    68821 tcatacaaac aacaagacca cctaagaaag tagctgtaca ggaacgaagt ctagatcgca
    68881 taacttccca tttgagcccc ttactcatat agacttgatc ctctggaagt aaatcagaag
    68941 acgatttacg aagaatcgaa caagaacctg ctcctatcaa ttcccaacct ctatctctaa
    69001 aatcttgcag ttcacgctta tgctctttaa gaaatctaga atcatagata cgatagataa
    69061 catcgtccgg ttgaccttgc tcaaaataga acaaaccaaa acgactcgtt ctatacctcc
    69121 aacctttcaa atgcatctca tgtaaatatt cttctttctt gtccaaatca acaatggtga
    69181 aaatccgaaa ttctactctg ctattcattg tcttacccca aaattagaaa acatgcctgg
    69241 cgttatttat tagataattc tttccacttt tgactcaatc tccaaaaaat ataagaaatc
    69301 tgaatcgcaa aaactatcaa taaaacccaa tctattatga aaatcaaaaa cactttccaa
    69361 ctgaaagaac tacctccagt aacaaacttt gagaaaaacg gtagtagagc taaaaagaga
    69421 agtaaaatag gaagcatccg cattgttaaa atccgtttgg cataaaaaaa tctttattta
    69481 aactaaaata ttatagcaaa atttacgcca gtttttgaac ggctgatgta gatattttat
    69541 actttcaaaa tgtttaaatg tgattattta tttttgaaaa atagctcacc agcccgactg
    69601 aaagtgctta tagaatgata ataagtcgcc tgccgaaaac agcggaaaat agcggtgtta
    69661 tgcggagata atctgacgcg atgcgaaagt atattgcata cttattttca acaatttagc
    69721 agagtatttt tataagtgtg atataataga agtataattt gttctgatag tttattttat
    69781 ggagaagtag atttttagaa tgcggagggt tcaatatggt tgagtttata aagtctaaga
    69841 aagaaatgag tgaggaggat attaaagcaa atttcatcac tcctgctatt gtatccaaag
    69901 gatggaaaaa tggtgagcat atcgcttacg aagaatactt cactgatggt cgaattgaag
    69961 ttagaggaga taaggctcgt cgtaaagaag gaaaaaaatc agactattca ctgtattacc
    70021 aatttggaac tcgaattgca attgttgagg caaaggataa taaacacagc gttcgagcag
    70081 gattacaaca agctattgaa tatggagaga ttttagatgt tccatttgtt tattcttcga
    70141 atggtgatgg ctttattgaa cacgaccgta tcacgagaga agaacgtgag ctggagttag
    70201 acgaattccc tactcgtgaa gaattatttt ctcgtatgac gaaggaaaaa ggattgacgt
    70261 acgaaattac agaagctatc tcaactccat actatacaga cgccttctca atgaaaacgc
    70321 cacgctatta tcagcaaata gctatcaacc gtactattga aacagttgcc agaggacaaa
    70381 aacgagtaat gtttgtgatg gcaacaggaa cggggaaaac gttcatggct tttcaaatta
    70441 ttcatcgcct tcgaaaagct ggtttggcta aacgagtttt attcttagca gatagaaaca
    70501 tcttagtaga ccaaacgatg gctgaagact ttaggccatt cgaaaaggta atgacgaaaa
    70561 ttacaccaaa acttttgact gctcctgaaa aattaaattc ttttgaaatt tatctagggc
    70621 tttatcagca actaactggt gaagatggaa ctgaaacaca ttatcaaaaa tttgacaaag
    70681 acttctttga tttaatcgta attgatgaag cacaccgtgg ttcagctaag gaaaacagta
    70741 actggcgtaa ggtaattgat tatttcagtt ctgcgacaca gattgggatg accgctactc
    70801 ctaaagaaac caagaatgct tccaatacgg aatactttgg tgagccaatc tatacttata
    70861 gtttaaaaca gggaatcgag gatggttttt tggctccata tcgtgttatg agggttaatt
    70921 tagatgtgga tgtggatggt tatcgtccag aaactggaaa agttgatgct aacggacaat
    70981 taatagaaga taggtactac ggcaggaaag attttgataa aaccattgtc attgatgata
    71041 gaacgcaaag agttgccaag tttgtttctg attatatgaa gcaaaacaat gcacgatttg
    71101 ataaaacaat tgttttttgt gttgatattg accatgccga gcgaatgcgt gctgcacttg
    71161 taaaagagaa tctagcctta gtccaagaag actatcgtta tgtcatgcaa gtaactggtg
    71221 acaacgctga aggaaaagct caactggata actttatgga tgtcaattct aattttcccg
    71281 ctattgtaac aacgtctaaa ttattaacga caggagttaa tgctaaaaca tgtcgtttga
    71341 ttgttttaga ctctaatatc caatccatga ctgaatttaa acaaattatt ggtcgtggca
    71401 cacgtcttta tcctcaaaag gggaaagaat tttttacgat tattgatttt cgaaatgtta
    71461 ccaatttgtt tgctgaccct gattttgatg gtgatccagt gaaggtgctg gaaacaggtg
    71521 cgaaaacagt cagtggttct acgcccggtt tcgtagatga ggaaggtgac ccagtagaaa
    71581 aatatatcgt tacagacaag caggttacca ttcttaattc tactgttcaa gtattggatg
    71641 aaaacgggaa actgattacc gaaagcctga ccgactacac tcgaaagaat atcttaggta
    71701 gctacgccac tttgaacgat tttatcacag tttggcatac ggcagataaa aagaagctta
    71761 tcttagacga actttataaa aaaggagttt atctagatgc tattcgagag tcggagggaa
    71821 tatcagaaca agaaatcgat gattttgatt tactcctaaa acttgcctat ggtcaaaaag
    71881 aattaaccaa aacggaacgt atcaataaac tcaaacaaag cggatattta tataaatata
    71941 gtgaggaagc gcgtgctgtt ttggaaattt tactgaacaa atacatggat aaaggtattg
    72001 gagaactcga aagcattgaa acattaaaac ttccagaatt tcagatatat ggtggaacct
    72061 tcaaaatcat caatacttat tttggagata aaaaacgata tttacaagca attaaagaat
    72121 tggagcaaga gctatttaca gtagcttaat gaaaggaaag tatgtcaatt acatcatttg
    72181 taaaaagaat tcaagatatc actcgaaacg atgctggtgt taatggtgat gctcaacgta
    72241 ttgagcaaat gtcttggtta ttattcttaa aaatttatga tagccgtgaa atggtttggg
    72301 aattagaaga agacgagtat gagtcaatta tcccagagga attaaaatgg cgaaattggg
    72361 ctcatgctca aaatggggaa cgggtattga caggcgatga attacttgat tttgtcaata
    72421 acaagttatt caaagagttg aaagagcttg aaataacttc aattatgcct attcgaaaaa
    72481 cgattgttaa atcagctttt gaagatgcga acaactatat gaaaaatggc gtcttgttac
    72541 gccaagtcat caatgttatt gatgaagttg atttcaatag ccctgaagat cgtcattcgt
    72601 ttaatgatat ttacgaaaaa attcttaaag atattcaaaa tgctgggaac tcaggagaat
    72661 tttatacgcc acgtgcagcg actgatttta ttgccgaagt tcttaaccca aaacttggag
    72721 aatcaatggc agaccttgct tgcggaacag gaggcttctt gacttcgact ctgaaccgtt
    72781 taagtagtca acgtaaaact agtgaagata ccaaaaaata taatacagct gtttttggta
    72841 ttgaaaagaa agcatttcct catcttttag cagttacaaa tctgtttctt cacgaaattg
    72901 atgaccctaa aattgttcat ggaaatactt tggagaaaaa tgttcgtgaa tatacggatg
    72961 atgaaaaatt tgacattatt atgatgaatc caccttttgg agggtcagaa ttagaaacaa
    73021 taaaaaataa ctttccagca gaattacgga gttctgaaac agctgattta tttatggctg
    73081 tcattatgta tcgtttgaaa gaaaatggtc gtgttggagt tattttacct gatggttttc
    73141 tatttggtga aggtgtaaaa actcgcttga aacaaaaact ggtagatgag ttcaacttgc
    73201 atacgattat taggttgcct catagtgtct ttgcaccgta tacaggaatc catacgaaca
    73261 ttcttttctt tgataaaaca aagaaaacag aagaaacttg gttttatcgt ttagatatgc
    73321 cagatggtta taaaaatttc tcgaaaacta agccgatgaa gtcagaacac ttcaatcctg
    73381 ttcgtgactg gtgggaaaat cgtgaagaga ttctggaagg taagttctac aaatctaaat
    73441 catttacacc tagtgaattg gctgagttga attataattt agaccagtgt ggttttccaa
    73501 aagaggaaga ggaaatctta aatccctttg agttgattca gaattatcaa gcggaaagag
    73561 caactttaaa tcataagatt gataatgtat tagctgatat tttgcagttg ttggaggaca
    73621 aataatgaca ccagaacaac ttaaagcaag tattctccaa agagcgatgg aagggaaatt
    73681 agtgccgcaa aatcccaatg acgaacctgc aagtgaatta ttaaagagaa ttaaagctga
    73741 aaaagaaaaa cttatcagtg aaggaaaaat caaacgagat aaaaaggaaa ctgagatatt
    73801 tcgtggtgat gatg
//
LOCUS       DBEJHE010000009        70075 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC4 isolate 671759
            SAMN38261586-rid24793303.denovo.09, whole genome shotgun sequence.
ACCESSION   DBEJHE010000009 DBEJHE010000000
VERSION     DBEJHE010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261586
            Sequence Read Archive: SRR26833752
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 70075)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 70075)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576136.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576136.1
            Genome Coverage       :: 109x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 19:48:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,067
            CDSs (total)                      :: 2,029
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 131
            CDSs (without protein)            :: 131
            Pseudo Genes (ambiguous residues) :: 0 of 131
            Pseudo Genes (frameshifted)       :: 64 of 131
            Pseudo Genes (incomplete)         :: 59 of 131
            Pseudo Genes (internal stop)      :: 46 of 131
            Pseudo Genes (multiple problems)  :: 32 of 131
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..70075
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261586-rid24793303.denovo.09"
                     /strain="GPSC4"
                     /isolate="671759"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            1..175
                     /locus_tag="ACL3EZ_000774"
                     /pseudo
     CDS             1..175
                     /locus_tag="ACL3EZ_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019770457.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            complement(557..2446)
                     /locus_tag="ACL3EZ_000775"
     CDS             complement(557..2446)
                     /locus_tag="ACL3EZ_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2207 domain-containing protein"
                     /protein_id="HGR0392379.1"
                     /translation="MKKTFFLLVLGLFCLLPLSVFAIDFKINSYQGDLYIHADNTAEF
                     RQKIVYQFEEDFKGQIVGLGRAGKMPSGFDIDPHPKVQAAKNGAELADVTSEVTEEAD
                     GYTVRVYNPGQEGDIVEVDLVWNLKNLLFLYDDIAELNWQPLTDSSESIEKFEFHVRG
                     DKGAEKLFFHTGKLFREGTIEKSNLDYTIRLDNLPAKRGVELHAYWPRTDFASARDQG
                     LKGNRLEEFNKIEDSIVREKDQSKQLVTWVLPSILSISLLLSVCFYFIYRRKTTPSVK
                     YAKNHRLYEPPMELEPMVLSEAVYSTSLEEVSPLVKGAGKFTFDQLIQATLLDVMDRG
                     NVSIISEGDAVGLRLVKEDGLSRFERDCLNLAFSGKKEATLSNLFADYKVSDSLYRGA
                     KAADEKRIQARGIQLKSSFEEVLNQMQEGVRKRVVFWGLPDYYRPLTGLEKALQVGMG
                     VLTILPLFIGFGLFLYSLDVHGYLYLPLPILGFLGLVLSVFYYWKLRLDNRDGVLNEA
                     GAEVYYLWTSFENMLREIARLDKAELESIVVWNRLLVYATLFGYADKVSHLMKVHQIQ
                     VENPDINLYVAYGWHSMFYHSSAQMSHYASVANTASTYSVSSGSGSSGGGFSGGGGGG
                     SIGAF"
     gene            2584..4149
                     /locus_tag="ACL3EZ_000776"
     CDS             2584..4149
                     /locus_tag="ACL3EZ_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HGR0392380.1"
                     /translation="MRKIYLSIFTSLLLMLGLVNVTQADEYLRIGMEAAYAPFNWTQD
                     DDSNGAVKIDGTNQYANGYDVQIAKKIAKDLGKEPLVVKTKWEGLVPALTSGKIDMII
                     AGMSPTAERKQEIAFSSSYYTSEPVLLVKKDSAYASAKSLDDFNGAKITSQQGVYLYD
                     LIAQIPGAKKETAMGDFAQMRQALEAGVIDAYVSERPEALTAEAANSKFKMIQVEPGF
                     KTGEEDTAIAIGLRKNDNRISQINASIETISKDDQVALMDRMIKEQPAEATTTEETSS
                     SFFSQVAKILSENWQQLLRGAGITLLISIVGTIIGLIIGLAIGVFRTAPLSENKAIYG
                     LQKLVGWVLNVYIEIFRGTPMIVQSMVIYYGTAQAFGINLDRTLAAIFIVSINTGAYM
                     TEIVRGGILAVDKGQFEAATALGMTHNQTMRKIVLPQVVRNILPATGNEFVINIKDTS
                     VLNVISVVELYFSGNTVATQTYQYFQTFTIIAVIYFVLTFTVTRILRFIERRMDMDTY
                     TTGANQMQTEDLK"
     gene            4149..4889
                     /locus_tag="ACL3EZ_000777"
     CDS             4149..4889
                     /locus_tag="ACL3EZ_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HGR0392381.1"
                     /translation="MTQAILEIKHLKKSYGQNEVLKDISLTVHKGEVISIIGSSGSGK
                     STFLRSINLLETPTDGQILYHGQNVLEKGYDLTQYREKLGMVFQSFNLFENLNVLENT
                     IVAQTTVLKRERTEAEKIAKENLEKVGMGERYWQAKPKQLSGGQKQRVAIARALSMNP
                     DAILFDEPTSALDPEMVGEVLKIMQDLAQEGLTMIVVTHEMEFARDVSHRVIFMDKGV
                     IAEEGKPEDLFTNPKEDRTKEFLQRYLK"
     gene            complement(4998..5213)
                     /locus_tag="ACL3EZ_000778"
     CDS             complement(4998..5213)
                     /locus_tag="ACL3EZ_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0392382.1"
                     /translation="MAKSNFEKVESVVGWVRDKKITGYRISKETNAREMSIIALAQGR
                     AKVKNISFETALGLIDFYEKNYEKFED"
     gene            complement(6084..7334)
                     /gene="ilvA"
                     /locus_tag="ACL3EZ_000779"
     CDS             complement(6084..7334)
                     /gene="ilvA"
                     /locus_tag="ACL3EZ_000779"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004794 - threonine deaminase activity
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase IlvA"
                     /protein_id="HGR0392383.1"
                     /translation="MLSSKDIIKAHKVLNGVVVNTPLDYDHYLSEKYGAKIYLKKENA
                     QRVRSFKIRGAYYAISQLSKEERERGVVCASAGNHAQGVAYTCNEMKIPATIFMPITT
                     PQQKIGQVRFFGGDFVTIKLVGDTFDASAKAAQEFTVSENRTFIDPFDDAHVQAGQGT
                     VAYEILEEARKESIDFDAVLVPVGGGGLIAGVSTYIKETSPEIEVIGVEANGARSMKA
                     AFEAGGPVKLKEIDKFADGIAVQKVGQLTYEATRQHIQTLVGVDEGLISETLIDLYSK
                     QGIVAEPAGAASIASLEVLAEYIKGKTICCIISGGNNDINRMPEMEERALIYDGIKHY
                     FVVNFPQRPGALREFVNDILGPNDDITRFEYIKRASKGTGPVLIGIALADKHDYAGLI
                     RRMEGFDPAYINLNGNETLYNMLV"
     gene            complement(7384..7740)
                     /locus_tag="ACL3EZ_000780"
     CDS             complement(7384..7740)
                     /locus_tag="ACL3EZ_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001027901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HGR0392384.1"
                     /translation="MNITNLFSIKTGCDETDRQLQKLFFQLDLQLGELTDQLRKLDSN
                     FVPRSQFVDTLDLNDVEYKEILNYFIFHRNDSEESLVEWLYDWISTNRYELPKEFSIR
                     MAHKYHESVTEIFGDE"
     gene            complement(7978..8214)
                     /locus_tag="ACL3EZ_000781"
     CDS             complement(7978..8214)
                     /locus_tag="ACL3EZ_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0392385.1"
                     /translation="MLADQNKADWSYDENAVINIYDDANFEDGRLHMTFEQFFKLAQI
                     AREEGLEIHSPFERAGATKSARYIAKWILRNKKY"
     gene            complement(8321..9343)
                     /gene="ilvC"
                     /locus_tag="ACL3EZ_000782"
     CDS             complement(8321..9343)
                     /gene="ilvC"
                     /locus_tag="ACL3EZ_000782"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HGR0392386.1"
                     /translation="MTVQMEYEKDVKVAALDGKKIAVIGYGSQGHAHAQNLRDSGRDV
                     IIGVRPGKSFDKAKEDGFDTYTVAEATKLADVIMILAPDEIQQELYEAEIAPNLEAGN
                     AVGFAHGFNIHFEFIKVPADVDVFMCAPKGPGHLVRRTYEEGFGVPALYAVYQDATGN
                     AKNIAMDWCKGVGAARVGLLETTYKEETEEDLFGEQAVLCGGLTALIEAGFEVLTEAG
                     YAPELAYFEVLHEMKLIVDLIYEGGFKKMRQSISNTAEYGDYVSGPRVITEQVKENMK
                     AVLADIQNGKFANDFVNDYKAGRPKLTAYREQAANLEIEKVGAELRKAMPFVGKNDDD
                     AFKIYN"
     gene            complement(9409..9885)
                     /gene="ilvN"
                     /locus_tag="ACL3EZ_000783"
     CDS             complement(9409..9885)
                     /gene="ilvN"
                     /locus_tag="ACL3EZ_000783"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002927678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1990610 - acetolactate synthase regulator
                     activity [Evidence IEA];
                     GO_process: GO:0009082 - branched-chain amino acid
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HGR0392387.1"
                     /translation="MRRMLTAKLQNRSGVLNRFTGVLSRRQVNIESISVGATEDPNVS
                     RITIIIDVASHDEVEQIIKQLNRQIDVIRIRDITDKPHLEREVILVKMSAPAEKRAEI
                     LAIIQPFRATVVDVAPSSITIQMTGNAEKSEALLRVIRPYGIRNIARTGATGFTRD"
     gene            complement(9878..11578)
                     /locus_tag="ACL3EZ_000784"
     CDS             complement(9878..11578)
                     /locus_tag="ACL3EZ_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase large subunit"
                     /protein_id="HGR0392388.1"
                     /translation="MEKISLESPKTGSDLVLETLRDLGVDTIFGYPGGAVLPFYDAIY
                     NFKGIRHILGRHEQGCLHEAEGYAKSTGKLGVAVVTSGPGATNAITGIADAMSDSVPL
                     LVFTGQVARAGIGKDAFQEADIVGITMPITKYNYQVRETADIPRIITEAVHIATTGRP
                     GPVVIDLPKDISALETDFIYSPEVNLPSYQPTLEPNDMQIKKILKQLSKAKKPVLLAG
                     GGISYAEAATELNEFAERYQIPVVTSLLGQGTIATSHPLFLGMGGMHGSFAANIAMTE
                     ADFMISIGSRFDDRLTGNPKTFAKNAKVAHIDIDPAEIGKIISADIPVVGDAKKALQM
                     LLAEPTVHNNTEKWIEKVTKDKNRVRSYDKKERVVQPQAVIERIGELTNGDAIVVTDV
                     GQHQMWTAQYYPYQNERQLVTSGGLGTMGFGIPAAIGAKIANPDKEVVLFVGDGGFQM
                     TNQELAILNIYKVPIKVVMLNNHSLGMVRQWQESFYEGRTSESVFDTLPDFQLMAQAY
                     GIKNYKFDNPETLAQDLEVITEDVPMLIEVDISRKEQVLPMVPAGKSNHEMLGVQFHA
                     "
     gene            complement(11778..13445)
                     /locus_tag="ACL3EZ_000785"
     CDS             complement(11778..13445)
                     /locus_tag="ACL3EZ_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HGR0392389.1"
                     /translation="MSKITTSLFQEMVQAASTRLNKQAEYVNSLNVFPVPDGDTGTNM
                     GMTIENGAKEVADKPASTVGEVASILAKGLLMGARGNSGVITSQLFRGFSQAIKDKDE
                     LTGQDLALAFQSGVEVAYKAVMKPVEGTILTVSRGAAIGAKKKAEQTDDTVEVMSAAL
                     EGAKTALAKTPDMLPVLKEVGVVDSGGQGLVFIYEGFLSALTGEYIASEDFVATPANM
                     SEMINVEHHKSVAGHVATEDITFGYCTEIMVALKQGPTYAKDFDYDEFRNYLDELGDS
                     LLVVNDDEIVKVHVHTEDPGLVMQEGLKYGSLVKVKVDNMRNQHEAQVEKEATQVIKS
                     AEEKEYALIAVVAGKGLADIFCSQGVDYVIEGGQTMNPSTEDFIKAVEQVNARNIIFL
                     PNNKNIFMAAQSAAEVLEQPAVVVEARTLPQGMTSLLAFDPSKSIEENQERMTAALSD
                     VVSGSVTTAVRDTTIDGLEIHENDNLGMVDGKILVSNPDMHQTLTETLKHMLDEDSEI
                     VTFYVGEDGSEELANEIAQEIVEEFEDVEVEIHQGQQPVYPYLFSVE"
     gene            complement(13448..13813)
                     /locus_tag="ACL3EZ_000786"
     CDS             complement(13448..13813)
                     /locus_tag="ACL3EZ_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HGR0392390.1"
                     /translation="MTVKINTKDGQIELTDEVIATVVGGAATEIFGVVGMASKNALKD
                     NFQALLGKENYSKGVVVKAAEDGSIAVDVYTVLSYGTKISEVSKNIQERVAFSLENQL
                     GITAQTVNVYIQNIKVVGE"
     gene            complement(13970..14158)
                     /gene="rpmB"
                     /locus_tag="ACL3EZ_000787"
     CDS             complement(13970..14158)
                     /gene="rpmB"
                     /locus_tag="ACL3EZ_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HGR0392391.1"
                     /translation="MAKVCYFTGRKTVSGNNRSHAMNQTKRAVKPNLQKVTVLIDGKP
                     KKVWASARALKSGKVERV"
     gene            complement(14277..14759)
                     /locus_tag="ACL3EZ_000788"
                     /pseudo
     CDS             complement(14277..14759)
                     /locus_tag="ACL3EZ_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001204109.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
     gene            complement(15201..16745)
                     /locus_tag="ACL3EZ_000789"
     CDS             complement(15201..16745)
                     /locus_tag="ACL3EZ_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HGR0392392.1"
                     /translation="MNIQEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVK
                     GKKTGTFAKSDWMDIEKQRGISVTSSVMQFDYDGKRVNILDTPGHEDFSEDTYRTLMA
                     VDAAVMVVDSAKGIEAQTKKLFEVVKHRGIPVFTFMNKLDRDGREPLDLLQELEEILG
                     IASYPMNWPIGMGKAFEGLYDLYNQRLELYKGDERFASLEDGDKLFGSNPFYEQVKDD
                     IELLNEAGNEFSEEAILAGELTPVFFGSALTNFGVQTFLETFLKFAPEPHGHKKTDGE
                     IVDPYDKDFSGFVFKIQANMDPRHRDRIAFVRIVSGEFERGMSVNLPRTGKGAKLSNV
                     TQFMAESRENVINAVAGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPEIFMKVS
                     AKNVMKQKSFHKGIEQLVQEGAVQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAE
                     VVMNPMGKKTVRWIKPEDLDERMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDV
                     ELEEKM"
     gene            16958..17260
                     /gene="gatC"
                     /locus_tag="ACL3EZ_000790"
     CDS             16958..17260
                     /gene="gatC"
                     /locus_tag="ACL3EZ_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030956 - glutamyl-tRNA(Gln)
                     amidotransferase complex [Evidence IEA];
                     GO_function: GO:0050567 - glutaminyl-tRNA synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA];
                     GO_process: GO:0006450 - regulation of translational
                     fidelity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HGR0392393.1"
                     /translation="MKITQEEVTHVANLSKLRFSEKETAAFATTLSKIVDMVELLGEV
                     DTTGVAPTTTMADRKTVLRPDVAEEGTDRDRLFKNVPEKDNYYIKVPAILDDGGDA"
     gene            17260..18726
                     /gene="gatA"
                     /locus_tag="ACL3EZ_000791"
     CDS             17260..18726
                     /gene="gatA"
                     /locus_tag="ACL3EZ_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030956 - glutamyl-tRNA(Gln)
                     amidotransferase complex [Evidence IEA];
                     GO_function: GO:0050567 - glutaminyl-tRNA synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HGR0392394.1"
                     /translation="MTFNNKTIEELHNLLVSKEISATELTQATLENIKSREEALNSFV
                     TIAEEQALVQAKAIDEAGIDADNVLSGIPLAVKDNISTDGILTTAASKMLYNYEPIFD
                     ATAVANAKTKGMIVVGKTNMDEFAMGGSGETSHYGATKNAWDHSKVPGGSSSGSAAAV
                     ASGQVRLSLGSDTGGSIRQPAAFNGIVGLKPTYGTVSRFGLIAFGSSLDQIGPFAPTV
                     KENALLLNAIASEDAKDSTSAPVRIADFTSKIGQDIKGMKIALPKEYLGEGINPEVKE
                     TILNAAKHFEKLGAIVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRAEDA
                     TNLDEIYVNSRSQGFGEEVKRRIMLGTFSLSSGYYDAYYKKAGQVRTLIIQDFEKVFA
                     DYDLILGPTAPSVAYDLDSLNHDPVAMYLADLLTIPVNLAGLPGISIPAGFSQGLPVG
                     LQLIGPKYSEETIYQAAAAFEATTDYHKQQPVIFGGDN"
     gene            18726..20168
                     /gene="gatB"
                     /locus_tag="ACL3EZ_000792"
     CDS             18726..20168
                     /gene="gatB"
                     /locus_tag="ACL3EZ_000792"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016884 - carbon-nitrogen ligase activity,
                     with glutamine as amido-N-donor [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HGR0392395.1"
                     /translation="MNFETVIGLEVHVELNTNSKIFSPTSAHFGNDQNANTNVIDWSF
                     PGVLPVLNKGVVDAGIKAALALNMDIHKKMHFDRKNYFYPDNPKAYQISQFDEPIGYN
                     GWIEVKLEDGTTKKIGIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMR
                     SPEEAYAYLTALKEVIQYAGISDVKMEEGSMRVDANISLRPYGQEKFGTKTELKNLNS
                     FSNVRKGLEYEVQRQAEILRSGGQIRQETRRYDEANKATILMRVKEGAADYRYFPEPD
                     LPLFEISDEWIEEMRTELPEFPKERRARYVSDLGLSDYDASQLTANKVTSDFFEKAVA
                     LGGDAKQVSNWLQGEVAQFLNAEGKTLEQIELTPENLVEMITIIEDGTISSKIAKKVF
                     VHLAKNGGGAREYVEKAGMVQISDPAILIPIIHQVFADNEAAVADFKSGKRNADKAFT
                     GFLMKATKGQANPQVALKLLAQELAKLKEN"
     gene            20297..20857
                     /gene="efp"
                     /locus_tag="ACL3EZ_000793"
     CDS             20297..20857
                     /gene="efp"
                     /locus_tag="ACL3EZ_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HGR0392396.1"
                     /translation="MIEASKLKAGMTFETADGKLIRVLEASHHKPGKGNTIMRMKLRD
                     VRTGSTFDTSYRPEEKFEQAIIETVPAQYLYKMDDTAYFMNTETYDQYEIPVVNVENE
                     LLYILENSDVKIQFYGTEVIGVTVPTTVELTVAETQPSIKGATVTGSGKPATMETGLV
                     VNVPDFIEAGQKLVINTAEGTYVSRA"
     gene            20879..21268
                     /locus_tag="ACL3EZ_000794"
     CDS             20879..21268
                     /locus_tag="ACL3EZ_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HGR0392397.1"
                     /translation="MGIEEQLGEIVIAPRVLEKIIAIATAKVEGVHSFSNRSVSDTLS
                     KLSLGRGVYLKNVDEELTADIYLYLEYGVKVPKVAVAIQKAVKDAVRNMADVELAAIN
                     IHVAGIVPDKTPKPELKDLFDEDFLND"
     gene            21261..21683
                     /gene="nusB"
                     /locus_tag="ACL3EZ_000795"
     CDS             21261..21683
                     /gene="nusB"
                     /locus_tag="ACL3EZ_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000203663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HGR0392398.1"
                     /translation="MTSPLLESRRQLRKCAFQALMSLEFGTDVETACRFAYTHDREDT
                     DVQLPAFLIDLVSGVQAKKEELDKQITQHLKAGWTIERLTLVERNLLRLGVFEITSFD
                     TPQLVAVNEAIELAKDFSDQKSARFINGLLSQFVTEEQ"
     gene            complement(21802..21927)
                     /locus_tag="ACL3EZ_000796"
     CDS             complement(21802..21927)
                     /locus_tag="ACL3EZ_000796"
                     /EC_number="3.4.26.-"
                     /inference="COORDINATES: protein motif:HMM:NF014566.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family glutamic-type intramembrane
                     protease"
                     /protein_id="HGR0392399.1"
                     /translation="MILSHRDPISLLYYSLIGFFFALVYRFTDNLRLTILCHSFF"
     gene            complement(21982..22431)
                     /locus_tag="ACL3EZ_000797"
     CDS             complement(21982..22431)
                     /locus_tag="ACL3EZ_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0392400.1"
                     /translation="MRNTKKLRQFGIFLLIILLSTYLPQTIELYVTIILGLGADVYSL
                     ILTMVLVGSFLLLIWRLKKKKSWNWSFVFSLFATYVVYQILGNFWARYAHLINHRNIH
                     DEYFTVVLSNGQPTFLSTILSFVLPVIIGPVFEETLDRGYFMNTFFP"
     gene            complement(22449..22633)
                     /gene="briC"
                     /locus_tag="ACL3EZ_000798"
                     /pseudo
     CDS             complement(22449..22633)
                     /gene="briC"
                     /locus_tag="ACL3EZ_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148168.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm-regulating peptide BriC"
     gene            complement(22791..23558)
                     /locus_tag="ACL3EZ_000799"
     CDS             complement(22791..23558)
                     /locus_tag="ACL3EZ_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HGR0392401.1"
                     /translation="MNIAKIVREAREQSRLTTLDFATGIFDEFIQLHGDRSFRDDGAV
                     VGGIGWLGDQAVTVVGIQKGKSLQDNLKRNFGQPHPEGYRKALRLMKQAEKFGRPVVT
                     FINTAGAYPGVGAEERGQGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADRV
                     WMLENSIYAILSPEGFASILWKDGTRAMEAAELMKITSHELLEMDVVDKVISEVGLSS
                     KELIKSVKKELQTELARLSQKSLEELLEERYQRFRKY"
     gene            complement(23555..24421)
                     /gene="accD"
                     /locus_tag="ACL3EZ_000800"
     CDS             complement(23555..24421)
                     /gene="accD"
                     /locus_tag="ACL3EZ_000800"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001173351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase, carboxyltransferase
                     subunit beta"
                     /protein_id="HGR0392402.1"
                     /translation="MALFSKKDKYIRINPNRSVREKPQAKPEVPDELFSQCPGCKHTI
                     YQKDLGSERICPHCSYTFRISAQERLALTIDMGTFKELFTGIESKDPLHFPGYQKKLA
                     SMREKTGLHEAVVTGTALIKGQTVALGIMDSNFIMASMGTVVGEKITRLFEYATVEKL
                     PVVLFTASGGARMQEGIMSLMQMAKISAAVKRHSNAGLFYLTILTDPTTGGVTASFAM
                     EGDIILAEPQSLVGFAGRRVIENTVRESLPEDFQKAEFLLEHGFVDAIVKRRDLPDTI
                     ASLVRLHGGSPR"
     gene            complement(24458..25825)
                     /gene="accC"
                     /locus_tag="ACL3EZ_000801"
     CDS             complement(24458..25825)
                     /gene="accC"
                     /locus_tag="ACL3EZ_000801"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000488661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0004075 - biotin carboxylase activity
                     [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HGR0392403.1"
                     /translation="MFRKILIANRGEIAVRIIRAARELGIATVAVYSTADKEALHTLL
                     ADEAVCIGPGKATESYLNINAVLSAAVLTEAEAIHPGFGFLSENSKFATMCEEVGIKF
                     IGPSGHVMDMMGDKINARAQMIKAGVPVIPGSDGEVHNSEEALIVAEKIGYPVMLKAS
                     AGGGGKGIRKVEKPDDLVSAFETASSEAKANYGNGAMYIERVIYPARHIEVQILGDEH
                     GHVIHLGERDCSLQRNNQKVLEESPSIAIGKTLRHEIGAAAVRAAEFVGYENAGTIEF
                     LLDEASSNFYFMEMNTRVQVEHPVTEFVSGVDIVKEQICIAAGQPLSVKQEDIVLRGH
                     AIECRINAENPAFNFAPSPGKITNLYLPSGGVGLRVDSAVYPGYTIPPYYDSMIAKII
                     VHGENRFDALMKMQRALYELEIEGVQTNADFQLDLISDRNVIAGDYDTSFLMETFLPK
                     YQEKE"
     gene            complement(25837..26259)
                     /gene="fabZ"
                     /locus_tag="ACL3EZ_000802"
     CDS             complement(25837..26259)
                     /gene="fabZ"
                     /locus_tag="ACL3EZ_000802"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016836 - hydro-lyase activity [Evidence
                     IEA];
                     GO_function: GO:0019171 -
                     (3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HGR0392404.1"
                     /translation="MIDIQGIKEALPHRYPMLLVDRVLEVSEDTIVAIKNVTINEPFF
                     NGHFPQYPVMPGVLIMEALAQTAGVLELSKPENKGKLVFYAGMDKVKFKKQVVPGDQL
                     VMTATFVKRRGTIAVVEAKAEVDGKLAASGTLTFAIGN"
     gene            complement(26256..26741)
                     /gene="accB"
                     /locus_tag="ACL3EZ_000803"
     CDS             complement(26256..26741)
                     /gene="accB"
                     /locus_tag="ACL3EZ_000803"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001052236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HGR0392405.1"
                     /translation="MNLNDIKDLMTQFDQSSLREFSYKNGTDELQFSKNEARPVPEVA
                     TQVAPAPVLATPSPVAPTSAPAETVAEEVPAPAEASVATEGNLVESPLVGVVYLAAGP
                     DKPAFVTVGDSVKKGQTLVIIEAMKVMNEIPAPKDGVVTEILVSNEEMVEFGKGLVRI
                     K"
     gene            complement(26744..27979)
                     /gene="fabF"
                     /locus_tag="ACL3EZ_000804"
     CDS             complement(26744..27979)
                     /gene="fabF"
                     /locus_tag="ACL3EZ_000804"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HGR0392406.1"
                     /translation="MKLNRVVVTGYGVTSPIGNTPEEFWNSLATGKIGIGGITKFDHS
                     DFDVHNAAEIQDFPFDKYFVKKDTNRFDNYSLYALYAAQEAVNHANLDVEALNRDRFG
                     VIVASGIGGIKEIEDQVLRLHEKGPKRVKPMTLPKALPNMASGNVAMRFGANGVCKSI
                     NTACSSSNDAIGDAFRSIKFGFQDVMLVGGTEASITPFAIAGFQALTALSTTEDPTRA
                     SIPFDKDRNGFVMGEGSGMLVLESLEHAEKRGATILAEVVGYGNTCDAYHMTSPHPEG
                     QGAIKAIKLALEEAEISPEQVAYVNAHGTSTPANEKGESGAIVAVLGKEVPVSSTKSF
                     TGHLLGAAGAVEAIVTIEAMRHNFVPMTAGTSEVSDYIEANVVYGQGLEKEIPYAISN
                     TFGFGGHNAVLAFKRWENR"
     gene            complement(28001..28732)
                     /gene="fabG"
                     /locus_tag="ACL3EZ_000805"
     CDS             complement(28001..28732)
                     /gene="fabG"
                     /locus_tag="ACL3EZ_000805"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004316 - 3-oxoacyl-[acyl-carrier-protein]
                     reductase (NADPH) activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HGR0392407.1"
                     /translation="MKLEHKNIFITGSSRGIGLAIAHKFAQAGANIVLNSRGAISEEL
                     LAEFSNYGIKVVPISGDVSDFADAKRMIDQAIAELGSVDVLVNNAGITQDTLMLKMTE
                     ADFEKVLKVNLTGTFNMTQSVLKPMMKAREGAIINMSSVVGLMGNIGQANYAASKAGL
                     IGFTKSVAREVASRNIRVNVIAPGMIESDMTAILSDKIKEATLAQIPMKEFGQAEQVA
                     DLTVFLAGQDYLTGQVIAIDGGLSM"
     gene            complement(28766..29686)
                     /gene="fabD"
                     /locus_tag="ACL3EZ_000806"
     CDS             complement(28766..29686)
                     /gene="fabD"
                     /locus_tag="ACL3EZ_000806"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004314 - [acyl-carrier-protein]
                     S-malonyltransferase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HGR0392408.1"
                     /translation="MTKTAFLFAGQGAQYLGMGRDFYDQYPIVKETIDRASQVLGYDL
                     RYLIDTEEDKLNQTRYTQPAILATSVAIYRLLQEKGYQPDMVAGLSLGEYSALVASGA
                     LDFEDAVALVAKRGAYMEEATPADSGKMVAVLNTPVEVIEEACQKASELGVVTPANYN
                     TPAQIVIAGEVVAVDRAVELLQEAGAKRLIPLKVSGPFHTALLEPASQKLAETLAQVS
                     FSDFTCPLVGNTEAAVMQKEDIAQLLTRQVKEPVRFYESIGVMQEAGISNFIEIGPGK
                     VLSGFVKKIDQTAHLAHVEDQASLVALLEK"
     gene            complement(29679..30653)
                     /gene="fabK"
                     /locus_tag="ACL3EZ_000807"
     CDS             complement(29679..30653)
                     /gene="fabK"
                     /locus_tag="ACL3EZ_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0018580 - nitronate monooxygenase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HGR0392409.1"
                     /translation="MKTRITELLKIDYPIFQGGMAWVADGDLAGAVSKAGGLGIIGGG
                     NAPKEVVKANIDKIKSLTDKPFGVNIMLLSPFVEDIVDLVIEEGVKVVTTGAGNPSKY
                     MERFHEAGIIVIPVVPSVALAKRMEKIGADAVIAEGMEAGGHIGKLTTMTLVRQVATA
                     VSIPVIAAGGIADGEGAAAGFMLGAEAVQVGTRFVVAKESNAHPNYKEKILKARDIDT
                     TISAQHFGHAVRAIKNQLTRDFELAEKDAFKQEDPDLEIFEQMGAGALAKAVVHGDVE
                     GGSVMAGQIAGLVSKEETAEEILKDLYYGAAKKIQEEASRWTGVVRND"
     gene            complement(30772..30996)
                     /locus_tag="ACL3EZ_000808"
     CDS             complement(30772..30996)
                     /locus_tag="ACL3EZ_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000035 - acyl binding [Evidence IEA];
                     GO_function: GO:0000036 - acyl carrier activity [Evidence
                     IEA];
                     GO_process: GO:0009245 - lipid A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HGR0392410.1"
                     /translation="MAVFEKVQEIIVEELGKDASEVTLESTFDDLDADSLDLFQVISE
                     IEDAFDIQIEAENDLKTVGDLVAYVEEQAK"
     gene            complement(31057..32031)
                     /locus_tag="ACL3EZ_000809"
     CDS             complement(31057..32031)
                     /locus_tag="ACL3EZ_000809"
                     /EC_number="2.3.1.180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0033818 -
                     beta-ketoacyl-acyl-carrier-protein synthase III activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase III"
                     /protein_id="HGR0392411.1"
                     /translation="MAFAKISQVAHYVPEQVVTNHDLAQIMDTNDEWISSRTGIRQRH
                     ISRTESTSDLATEVAKKLMAKAGITGEELDFIILATITPDSMMPSTAARVQANIGANK
                     AFAFDLTAACSGFVFALSTAEKFIASGRFQKGLVIGSETLSKAVDWSDRSTAVLFGDG
                     AGGVLLEASEQEHFLAESLNSDGSRSECLTYGHSGLHSPFSDQESADSFLKMDGRTVF
                     DFAIRDVAKSIKQTIDESPIEVTDLDYLLLHQANDRILDKMARKIGVDRAKLPANMME
                     YGNTSAASIPILLSECVEQGLIPLDGSQTVLLSGFGGGLTWGTLILTI"
     gene            complement(32031..32465)
                     /locus_tag="ACL3EZ_000810"
     CDS             complement(32031..32465)
                     /locus_tag="ACL3EZ_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HGR0392412.1"
                     /translation="MDYQRINEYLTSIFNNVLVIEEVNLRGSRFKDISIKEMHTIDVI
                     GKAPDVTPSQVSKELMVTLGTVTTSLNNLERKGYIERVRSEQDRRVVHLHLTKKGRLI
                     HRLHKRFHKAMVEKIIDGMSEEEIAVMGKGLTNLYQFLEDLK"
     gene            complement(32559..33344)
                     /locus_tag="ACL3EZ_000811"
     CDS             complement(32559..33344)
                     /locus_tag="ACL3EZ_000811"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HGR0392413.1"
                     /translation="MEHIIYQLEEDLAILTLNRPEVANGFHIPMCEEILEALTLAEEN
                     PAVHFILINANGKVFSVGGDLVEMKRAVDEDDIPSLTKIAELVNTISYKIKQIAKPVL
                     MEVDGAVAGAAANMAVAADFCLATDKAKFIQAFVGVGLAPDAGGIHLLSRSIGVTRAA
                     QLAMTGEALTAEKALEWGLVYRVSEAEKLEKTREQLLKKLRRASSNSYAAIKKLVWES
                     QFKDWQGYATLELNLQKSLAQTEDFKEGVRAHSERRRPKFTGK"
     gene            33669..35033
                     /locus_tag="ACL3EZ_000812"
     CDS             33669..35033
                     /locus_tag="ACL3EZ_000812"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004072 - aspartate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HGR0392414.1"
                     /translation="MKVVKFGGSSLASASQLEKVLNIVKSDSERRFVVVSAPGKRNAE
                     DTKVTDALIKYYRDYVAGNDISKSQSWIIDRYAAMVSELGLKPAVLEKISKSIHALAT
                     LPIEENEFLYDTFLAAGENNNAKLTAAYFNQNGIDARYMHPREAGIVVTSEPGHARII
                     PSSYDKIEELTNTNEVLVIPGFFGVTKENQICTFSRGGSDITGSIIAAGVKADLYENF
                     TDVDGIFAAHPGIIHQPHSIPELTYREMRELAYAGFSVLHDEALLPAYRGKIPLVIKN
                     TNNPDHPGTRIVLKHSNDEFPVVGIAGDSGFVSINMSKYLMNREVGFGRKVLQILEEL
                     NIGWEHMPTGIDDLSIILRSRQLTPIKEEEILRQLVQKAKVDHAEIEHDLSIIMIVGE
                     KMKSHIGVTATATRALSENKINIQMMSQGSSEVSIMFVVNKDQEKAAIKALYNAFFGE
                     SKED"
     gene            35036..35407
                     /locus_tag="ACL3EZ_000813"
     CDS             35036..35407
                     /locus_tag="ACL3EZ_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HGR0392415.1"
                     /translation="MAQSLNKTVLLSTTGTSYLSIAGKVGKFLVGDQALEFYPDVNVE
                     QFIQIPWSHINQIGANVTGRKISRHFEVFTDKGKFLFASKDSGAILKIAREKLGNDKV
                     VKLPTLIQTISQKFKNLFAKK"
     gene            35621..36895
                     /gene="serS"
                     /locus_tag="ACL3EZ_000814"
     CDS             35621..36895
                     /gene="serS"
                     /locus_tag="ACL3EZ_000814"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004828 - serine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006434 - seryl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HGR0392416.1"
                     /translation="MLDIKRIRTDFEAVAEKLATRGVDAAVLNEMKEIDAKRRNILVK
                     VETLKAERNTVSAEIAQAKRNKENTDDKIAAMQNLSAEVKALDAELAEIDAKLTEFTT
                     TLPNIPADSVPVGADEDDNVEVRRWGTPREFDFEPKAHWDLGEDLGILDWERGGKVTG
                     ARFLFYKGLGARLERAIYNFMLDEHGKEGYTEVITPYIVNHDSMFGTGQYPKFKEDTF
                     ELSDTNFVLIPTAEVPLTNYYRDEILDGKDLPIYFTAMSPSFRSEAGSAGRDTRGLIR
                     LHQFHKVEMVKFAKPEESYEELEKMTANAENILQKLNLPYRVVALSTGDMGFSAAKTY
                     DLEVWIPAQNNYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTIPEALRPYMGGAEVIKP"
     gene            complement(36920..37819)
                     /locus_tag="ACL3EZ_000815"
     CDS             complement(36920..37819)
                     /locus_tag="ACL3EZ_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000735961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HGR0392417.1"
                     /translation="MKKLPLVFSGCLLGLAGAGNLILDTLPVLSHLFSLTGLVLWIYF
                     LILHLFNWKETKQELTKPPLLSGMATFPMAGMILSTYVFRVFSYLPLVAQGIWWFSFL
                     LDLTLIAGFTIKFACPGRRVHATPSWTVLYVGIAVAALTYPLVGIIEMAYATLSFGFL
                     LTFYLYPLIYSDLKKHPLPLALLGQEGIYCAPFSLLLASLVRVGGTSLPTWVLIVMIL
                     ASQSFFFFVLTRLPNILKQGFQPAFSALTFPTIITATSLKMAQGILKLPFLDYLVLAE
                     TIICLTILFFVLGAYLIWLRKKV"
     gene            complement(37929..38477)
                     /locus_tag="ACL3EZ_000816"
     CDS             complement(37929..38477)
                     /locus_tag="ACL3EZ_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000206764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HGR0392418.1"
                     /translation="MTTFTIHTVESAPAEVKEILETVEKDNNGYIPNLIGLLANAPTV
                     LEAYQIVSSIHRRNSLTPVEREVVQITAAVTNGCAFCVAGHTAFSIKQIQMNDDLIQA
                     LRNRTPIETDPKLDTLAKFTLAVINTKGRVGDEALSEFLEAGYTQQNALDVVFGVSLA
                     ILCNYANNLANTPINPELQPYA"
     gene            complement(38695..40017)
                     /locus_tag="ACL3EZ_000817"
     CDS             complement(38695..40017)
                     /locus_tag="ACL3EZ_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005283 - amino acid:sodium symporter
                     activity [Evidence IEA];
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine/glycine:cation symporter family protein"
                     /protein_id="HGR0392419.1"
                     /translation="MLELLKSIDAFAWGPPLLILLVGTGIYLTMRLGLLQVLRLPKAF
                     QLIFIQDKGHGDVSSFAALCTALASTVGTGNIIGVATAIKVGGPGALFWMWMAAFFGM
                     ATKYAEGLLAIKYRTKDDHGAVAGGPMHYILLGMGEKWRPLAVLFAVAGVLVVLLGIG
                     TFTQVNSIAESIQNTTTISPAITALVLSVFVAIAVFGGLKSISKVSTTVVPFMALIYI
                     LGTLTVIFFNIGKIPGTIALVFTSAFSPLAAVGGFAGASVRMAIQNGVARGVFSNESG
                     LGSAPIAAAAAKTNEPVEQGLISMTGTFIDTLIICTLTGLTILVTGVWSGDLNGVALT
                     QSAFSTVFSHFGPALLTIFLVLFAFTTILGWNYYGERCFEFLFGVRFIWLYRVVFVLM
                     VLLGGFIELDMVWIIADIVNALMALPNLIALLVLSPVVIAETKKYFDK"
     regulatory      complement(40108..40196)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            complement(40400..41962)
                     /locus_tag="ACL3EZ_000818"
     CDS             complement(40400..41962)
                     /locus_tag="ACL3EZ_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6287 domain-containing protein"
                     /protein_id="HGR0392420.1"
                     /translation="MKKFLLATTLLLTLVLGGCQYLPWNKSAETPSDSTSETSVATPE
                     IDYSSYNKVLDDYEKVAKGTLPTGMDVNPLASQVKSSQGFYTDVVYHKTDLNNDGVDE
                     LLLALEMKSGEKSLLDIRTLKDEKVIRLTNQENRLDQIGERMTVGILPDNSLLYRGAG
                     TATSHIYAHYQFSEDGQSLVKDKEAQELADLGVGSPISLETLSWKSVSDKLPGGSSAD
                     KGKPSVDYSPYNSILKDYEFILDYKSEVKDNINPTANIYAGMAERSQAFTYAMVDMDK
                     NGIDELIVSSKNGSEILDIFTLKDQKVIRLTNAENKMQMLGTRFKAYLLENGNLYTQW
                     NPFAGDPQTIHTIWKLNSSGDKLEKVKEAKTEDEVSPGTRMNLSSLTWKSVTEKFAAT
                     ASSTSKTASGKMDINAIKNGDFSSIEGRWSNGHGGEDLVFSKDGLIAPEKFKVDLTES
                     EFVNGFLRARYSAPDFGIFIQFVPAGVRIPDGTSRGELVTDASDISKDRIIFHAAFPL
                     HGDPRQFLYRVE"
     gene            complement(42103..43119)
                     /locus_tag="ACL3EZ_000819"
     CDS             complement(42103..43119)
                     /locus_tag="ACL3EZ_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase"
                     /protein_id="HGR0392421.1"
                     /translation="MNKKKLLVCAVALSTVGVVSTIDTAGVLPFSAQTVHAEITRTEN
                     HEVKSKITPGSENGSIYVDMTVENVPVHYHVYIYADIVNAKTGQIPRKDTFNERFDRS
                     SVPITKQGWTNFANVPDGEYYLQFHGEDDYRSVLYKFIGKSATFTVKDQKYVNPLDSS
                     TPKETEKPTATETSKPATNSSSGQTGWSGSSYYKAGVKVVNQWIFDVQYNSYFYLNAS
                     GNFVQNAWSGSYYLKSGGYMAKSEWIYDNNYQSYYYLTAEGSYARNAWSGSYYLKSDG
                     KMAKSEWIYDSSYQSYYYLTSEGSYARNTWVGDYYLKSDGKMAVNERTPDGYKVDGSG
                     KWVR"
     gene            complement(43178..44566)
                     /locus_tag="ACL3EZ_000820"
     CDS             complement(43178..44566)
                     /locus_tag="ACL3EZ_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HGR0392422.1"
                     /translation="MKSKTVLVTSLAAVTFGLVSLVDTAGALPFSAKTVQADTQTLTT
                     AAKYYILVPKDSEVFKNWRGTANRPIIWATKTTPELSYFQESARNYIANENKSGANYI
                     EWKGTVEEFKEAIKNLTDKKLTPNPAPIPQSDKKPTPDPTPNPQSTVPSGWSGSSYYQ
                     NGTKVTSKWIFDKNYNSYFYLDASGNYVQNAWEGDYYLKSGGYMAKKEWIYDKNYGAY
                     YYLTPDGYYARNTWVGNYYLKSNGKMAKSEWIYDKNYSSYYYLTSEGSYARNTWVGDY
                     YLKSNGKMAKGEWIYDNNYSSYYYLTSEGSYARNTWVGDYYLKSNGKMAVSERTPDGY
                     QVDGSGKWISSEGTHTASSSQATSLGISLYNVNDAMTYIDIALPSTPSSSYQVAYDFA
                     LVDANTGSVSTQTQFTVTYNPSLRVFQTRHFFSATPDGSYRFVIKGKGQDGKVYDGQS
                     VVFRVKNHRFVG"
     gene            complement(44742..45518)
                     /locus_tag="ACL3EZ_000821"
     CDS             complement(44742..45518)
                     /locus_tag="ACL3EZ_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001260022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0392423.1"
                     /translation="MRTNILKLSQFLNIFYLKIALLIFSCLYFIAPWFIVLKDFETYK
                     VQYPAVIGIAEFIVLTSFLVFVYISPIFFVIFLYKIIVGSINVRRCLIKIKNYKFYMI
                     VLNRIPLHTFMVYFSSVLLWIMYLTKPVDVSNALPLPIILPLEKINPFYMILGYWLLN
                     KRCEYQLHQYLYPVMRGSSHDGRIYALPEELFIWNRNRSQKIGKWKRDRRYNTTTDLV
                     EAQIGYSKFPFFLLATKWSVDPYDQNWTIGEKAYLTSRWK"
     gene            complement(45789..46610)
                     /locus_tag="ACL3EZ_000822"
     CDS             complement(45789..46610)
                     /locus_tag="ACL3EZ_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nuclease-related domain-containing protein"
                     /protein_id="HGR0392424.1"
                     /translation="MEKLLRFFKHRRNILYFILGFLWGRRQNAKVSPEPPTPSTPKHS
                     ELPSISKATHNGKMTGFEPQKLKTYQLYQHELMFGEPGKGLNKSGFDESAVNLGQEGE
                     INFAKALQKKGLLEKLVTFWSVHNLNLEDERVDADIDCVIVSGSTIWLVDLKFYASGN
                     VIYREADGLLYTIDSATGAQIGRPKKMSPNMSYAEESFSHKFASLLKYYRLETRVVLM
                     PTYKGAGRLDNVFWPGHIKAVSLEEMLDELSREDKFRDTIGGQMIRQTFNLLLKR"
     gene            complement(46626..47084)
                     /locus_tag="ACL3EZ_000823"
     CDS             complement(46626..47084)
                     /locus_tag="ACL3EZ_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000774 - adenyl-nucleotide exchange
                     factor activity [Evidence IEA];
                     GO_function: GO:0042803 - protein homodimerization
                     activity [Evidence IEA];
                     GO_function: GO:0051087 - protein-folding chaperone
                     binding [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HGR0392425.1"
                     /translation="MSEEVLHEKVSYIVDKVEDIESLITRRLLEDKAKNSLIEELKQY
                     LIYRQDLDKGEKFAPFMKQILQVIDRIESSEEKSDLLTSIAEELLQILSLNGLQVIDN
                     SGMIDPSMHEVVNTVAVTDEQSENNIVEVLQKGYLLNNRVLRPSKVTIAK"
     gene            complement(47092..48459)
                     /locus_tag="ACL3EZ_000824"
     CDS             complement(47092..48459)
                     /locus_tag="ACL3EZ_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000111449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HGR0392426.1"
                     /translation="MSVINYYEELGISETSSLDDVKKSIKSNRRRYRQLTGSPNIDQR
                     SMAERKMEVIAQAEKVFESEETRQKYDRELENSKQSSEGVPDSTPTNHSNSSYLDSAR
                     QAFYSGKKSLAYSYIEEALKINRNDADVWYFKAMISLEDRKLSDAELAISEANRLRPK
                     NADILSLLGDVYCEQNQQKFAIQYYQEAFELSNNSFYLLKKGRSLFLFDQYKQAVKDV
                     RYLYDHYLEENKNNEEYIYYLLSCSYREIGDNEEAYNFARKLVDVSDSLEHKLHYAGI
                     LFLKSEDECENYLDTLNERYGNNKDFQQVYFKLLLDITIERMKKAPDTDVEAFFRKYI
                     DRTKYENEAVLDNKARVRIAEAYLAKAQSLGIENKIIDNDFYNEFIENKNYINYATTR
                     HSQGMGCLMFILVFAANWFLSGFFDKFVHSFWISNALSLALLSNIVLYYNYPKGWQIN
                     RRKKG"
     gene            complement(48472..50010)
                     /locus_tag="ACL3EZ_000825"
     CDS             complement(48472..50010)
                     /locus_tag="ACL3EZ_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_function: GO:0140662 - ATP-dependent protein folding
                     chaperone [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp70 family protein"
                     /protein_id="HGR0392427.1"
                     /translation="MSKAIGIDLGTTYSAVSVLSETGQPQILLNQDGENLTPSVVFFQ
                     DFDGKDEPLVGIQAKNLAASRPEAVVQYVKRQMGNPNWKFDSPSDTVYTAEEISAIIL
                     KRLKEGAENALGDKVEDVVITVPAYFDDARRTATKHAGEIAGLNVLRVLNEPTAAALA
                     YGISAEKNETVLVYDLGGGTFDVTLMKIKDGEFDVIATDGDRNLGGFDFDNALSMIIA
                     EKMEEQGAEDIYTDEHFTALLREKSENTKRGLTTVEKTNVFLDYKGKSYKIPITRVEF
                     EEATKSLMNRTEELLDDVVEESGMSWDEIDQVLLIGGSTRMPMVQRKLEEKIGKKIVY
                     SINPDEAVAQGAAIQAALEIANKSESADVSETVRGLAEKLVVSDVTSQALGTLALSNG
                     VKRNTIIIPKNSKVPNKYSEYFSTVVDNQQNVLVEVTQGDDEDPQFVTVIGESTIKLP
                     GDWPAGTVLKVTYHYDVDQTVFVEVHDSDNHLLGTFEVERQANLDKSAVEVASRKIKD
                     LTID"
     gene            complement(50020..50547)
                     /locus_tag="ACL3EZ_000826"
     CDS             complement(50020..50547)
                     /locus_tag="ACL3EZ_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000598973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0392428.1"
                     /translation="MIKYKELKSYIDEWRYYSDENNPRLDLEYCKTKIVEKAKEFDLP
                     CQIDEEQIKLGGLFNKEIEECLVISHPNHQKDYVKFCFRLKNQGSVQLLTIDTLGESK
                     QLKKYYISEDNKRFREAIRESDLSLGQKLGAQLSNLTVSGLRTLGKNQSKIDAELQYC
                     EFLTEVLTQFRSNND"
     gene            50755..51684
                     /locus_tag="ACL3EZ_000827"
     CDS             50755..51684
                     /locus_tag="ACL3EZ_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001150386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGR0392429.1"
                     /translation="MQDESIYGLVYKTIREERGFTQKEAAGTTVTPHFLRQFEQGKSR
                     ITIQKFEEILSNIGIDKETFDSLKTQMFPTEFHKLQAQVADLAYKREFKKIISLINQP
                     MENPGIAEHYVIANRVVNKFAIANIIGDSFLTPKDYQELEYIKNYLSELDDWNKIEVN
                     IFSSILPHFSIEFLDYRLYHLLDTLKKQTEYHSIRTADYYIACLRTAIKHYSVNGYYD
                     KAESLAVKTLEVINTFPLLSTKMTEMISLSMERANNFLRKDDVRGLELAKHIFASLDN
                     FEKVYPNQLLTRMREDFFVTVTQLNHTGQPLDV"
     gene            complement(51734..54070)
                     /locus_tag="ACL3EZ_000828"
     CDS             complement(51734..54070)
                     /locus_tag="ACL3EZ_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HGR0392430.1"
                     /translation="MNKKILETLEFDKVKALFEPHLLTEQGLEQLRQLGPTAKADKIK
                     QAFAEMKEMQALFVEQPHFTILSTKEIAGVCKRLEMGAALNIEEFLLLKRVLLASREL
                     QSFYANLENVSLEELALWFEKLHDFPQLQGNLQAFNDAGFIENFASEELARIRRKIHD
                     SESRVRDVLQDLLKQKAQMLTEGIVASRNGRQVLPVKNTYRNKIAGVVHDISASGNTV
                     YIEPREVVKLSEEIASLRADERYEMLRILQEISERVRPHAAEIANDAWIIGHLDLIRA
                     KVRFIQERQAVVPQLSENQEIQLLHVCHPLVKNAVANDVHFGQDLTAIVITGPNTGGK
                     TIMLKTLGLTQVMAQSGLPILADKGSRVGIFEEIFADIGDEQSIEQSLSTFSSHMTNI
                     VDILGKVNQHSLLLLDELGAGTDPQEGAALAMAILEDLRLRQIKTMATTHYPELKAYG
                     IETAFVQNASMEFDTATLRPTYRFMQGVPGRSNAFEIAKRLGLSEVIVGDASQQVDQD
                     NDVNRIIEQLEEQTLESHKRLDNIREVEQENLKMNRALKKLYNELNREKETELNKARE
                     QAAEIVDMALSESDQILKNLHSKSQLKPHEIIEAKAKLKKLAPEKVDLSKNKILQKAK
                     KKRAPKVGDDIVVLSYGQRGTLTSQLKDGRWEAQVGLIKMTLEEKEFDLVQVQQEKPV
                     KKKQVNVVKRTSGRGPQARLDLRGKRYEEAMNELDAFIDQALLNNMAQVDIIHGIGTG
                     VIREGVTKYLQRNKHVKSFGYAPQNAGGSGATIVTFKG"
     gene            complement(54188..54736)
                     /locus_tag="ACL3EZ_000829"
     CDS             complement(54188..54736)
                     /locus_tag="ACL3EZ_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009403 - toxin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HGR0392431.1"
                     /translation="MISFLLLLVLVWGFYIGYRRGLLLQVYYLISAMASAFMAGQFYK
                     GLGEQFHLLLPYANSQEGQGTFFFPSDQLFQLDKVFYAGIGYLLVFGIVYSIGRLLGL
                     LLHLIPSKKLGGKLFQVSAGILSMLVTLFVLQMALTILATIPMAVIQNPLEKSIVAKH
                     IIQSIPITTSWLKQIWVTNLIG"
     gene            complement(54733..55035)
                     /gene="zapA"
                     /locus_tag="ACL3EZ_000830"
     CDS             complement(54733..55035)
                     /gene="zapA"
                     /locus_tag="ACL3EZ_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HGR0392432.1"
                     /translation="MANLNRFKFTFGKKSLTLTSEHDNLFMEEIAKVATEKYQAIKEQ
                     MPSADDETIALLLAVNCLSTQLSREIEFDDKEQELEELRHKLVTCKQEQSKIEDSL"
     gene            55122..56003
                     /gene="rnhC"
                     /locus_tag="ACL3EZ_000831"
     CDS             55122..56003
                     /gene="rnhC"
                     /locus_tag="ACL3EZ_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA];
                     GO_process: GO:0006401 - RNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HGR0392433.1"
                     /translation="MASITLTPSEKDIQAFLEHYQTSLAPSKNPYIRYFLKLPQATVS
                     IYTSGKILLQGEGAEKYASFFGYQAVEQTSGQNLPLIGTDEVGNGSYFGGLAVVAAFV
                     TPDQHDFLRKLGVGDSKTLTDQKIRQIAPILKEKIQHQALLLSPSKYNEVIGDRYNAV
                     SVKVALHNQAIYLLLQKGVQPEKIVIDAFTSAKNYDKYLAQEANRFSNPISLEEKAEG
                     KYLAVAVSSVITRDLFLENLENLGRELGYQLPSGAGTASDKVASQILQAYGMQGLSFC
                     AKLHFKNTEKAKKRLER"
     gene            56007..56621
                     /gene="lepB"
                     /locus_tag="ACL3EZ_000832"
     CDS             56007..56621
                     /gene="lepB"
                     /locus_tag="ACL3EZ_000832"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HGR0392434.1"
                     /translation="MNSFKNFLKEWGLFLLILSLLALSRIFFWSNVRVEGHSMDPTLA
                     DGEILFVVKHLPIDRFDIVVAHEEDGNKDIVKRVIGMPGDTIRYENDKLYINDKETDE
                     PYLADYIKRFKDDKLQSTYSGKGFEGNKGTFFRSIAQKAQAFTVDVNYNTNFSFTVPE
                     GEYLLLGDDRLVSSDSRHVGTFKAKDITGEAKFRLWPITRIGTF"
     gene            56749..59115
                     /locus_tag="ACL3EZ_000833"
     CDS             56749..59115
                     /locus_tag="ACL3EZ_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0043139 - 5'-3' DNA helicase activity
                     [Evidence IEA];
                     GO_process: GO:0032508 - DNA duplex unwinding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HGR0392435.1"
                     /translation="MEVYFSGTIERIIFENPSNFYRILLLEIDDTDAEDFDDFEIIVT
                     GTMADVIEGEDYTFWGQIVQHSKYGEQLQISRYDRAKPTSKGLVKYFSSSHFKGIGLK
                     TAQKIVDTYGENTIDEILQHPEKLEGIAGLSAKNREAFVSTLRLNYGTEMVLAKLANY
                     GIPNKLAFQIQDFYKEETLDVVENYPYQLVEDIKGLGFTIADQLAEELGIESQAPERF
                     RAGLVHSLFQACMETGDTYVEARDLLEQTLTLLESSRPVELDPSQVAQELSYLIEEDK
                     VQQIDTKIFDNSLFFAEEGIRSHLVRILEKGKQKSHDLKTIQKHITTIEQELGIEYDN
                     IQKQAICDAIQNKVFILTGGPGTGKTTVINGIIAVYALLEGLDFRKKSNLPILLAAPT
                     GRAARRMNELTGLPSATIHRHLGMTGDDDTSHLEDYLDADFIIVDEFSMVDTWLANQL
                     FSNISSNSKILIVGDSDQLPSVSPGQVLADLLHIPLIPQTRLEKIYRQSEESTIVTLA
                     SQIRQGILPADFTQKKADRSYFEIASGHIPATIEKILGAALRNGIPARDIQVLAPMYR
                     GTAGIDAINQLMQDLLNPPQKDQLSFEAPQCHYRKGDKVIHLVNDAEINVFNGDLGAI
                     TDLIPGKYTESKQDEIVIDFDGNEVSYPRNEWYKIRLAYAMSIHKSQGSEFPVVILPI
                     TSASRRMLERNLIYTAITRAKSKLILLGELQAFDYATQHIGTARKTYLIERFSDLLEN
                     VEEKQQAVSETVTSSASEQSYILTEENWDSIPAMIGITDTDLKEIFGK"
     gene            complement(59163..60446)
                     /gene="tig"
                     /locus_tag="ACL3EZ_000834"
     CDS             complement(59163..60446)
                     /gene="tig"
                     /locus_tag="ACL3EZ_000834"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005854 - nascent polypeptide-associated
                     complex [Evidence IEA];
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA];
                     GO_process: GO:0051083 - 'de novo' cotranslational protein
                     folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HGR0392436.1"
                     /translation="MSVSFENKETNRGVLTFTISQDQIKPELDRVFKSVKKSLNVPGF
                     RKGHLPRPIFDKKFGEESLYQDVMNALLPNAYEAAVKEAGLEVVAQPKIDVTSMEKGQ
                     DWVIAAEVVTKPEVKLGDYKNLEVSVDVEKEVTDADVEERIERERNNLAELVIKEAAA
                     ENGDTVVIDFVGSIDGVEFDGGKGENFSLGLGSGQFIPGFEDQLVGHSAGETVDVIVT
                     FPEDYQAEDLAGKEAKFVTTIHEVKAKEVPALDDELAKDIDEEVETLADLKEKYRKEL
                     AAAKEEAYKDAVEGAAIDTAVENAEIVELPEEMIHEEVHRSVNEFLGNLQRQGINPDM
                     YFQITGTTQEDLHNQYQAEAESRTKTNLVIEAVAKAEGFDASEEEIQKEVEQLAADYN
                     MEVAQVQNLLSADMLKHDITIKKAVELITSTATVK"
     gene            complement(60640..60999)
                     /locus_tag="ACL3EZ_000835"
     CDS             complement(60640..60999)
                     /locus_tag="ACL3EZ_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000378120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGR0392437.1"
                     /translation="MDSPKSLASYRVIGISDRVLEILKEYLLLEEGDYIFTNNGSPLM
                     ITCFNYFLKNRFRKSEIKKDDFVLTAHVFRYSHISLLAELEVPIIAIMDRVDYTNETK
                     ILSVYTHVTEKMKSNIT"
     gene            complement(61301..61891)
                     /gene="cbpG"
                     /locus_tag="ACL3EZ_000836"
                     /pseudo
     CDS             complement(61301..61891)
                     /gene="cbpG"
                     /locus_tag="ACL3EZ_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001100143.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpG"
     gene            complement(61972..62211)
                     /locus_tag="ACL3EZ_000837"
     CDS             complement(61972..62211)
                     /locus_tag="ACL3EZ_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0392438.1"
                     /translation="MKKTVYKKLGISIIASTLLASQLSTVSALSVISSTGEEYEVSET
                     LEKGPESNDSSLSEISPTYGSYYQKQSEVLSVMMI"
     gene            complement(62361..62906)
                     /locus_tag="ACL3EZ_000838"
                     /pseudo
     CDS             complement(62361..62906)
                     /locus_tag="ACL3EZ_000838"
                     /inference="COORDINATES: protein motif:HMM:NF020296.4"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            complement(62888..63129)
                     /locus_tag="ACL3EZ_000839"
                     /pseudo
     CDS             complement(62888..63129)
                     /locus_tag="ACL3EZ_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812384.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            complement(63130..63762)
                     /locus_tag="ACL3EZ_000840"
     CDS             complement(63130..63762)
                     /locus_tag="ACL3EZ_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HGR0392439.1"
                     /translation="MKILLVDDHEMVRLGLKSYFDLQADVEVVGEASNGSQGIDLALE
                     LRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIVTSYLDNEKIMPVLDAGAKGYML
                     KTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
                     ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGHEEF"
     gene            complement(63776..64771)
                     /locus_tag="ACL3EZ_000841"
     CDS             complement(63776..64771)
                     /locus_tag="ACL3EZ_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HGR0392440.1"
                     /translation="MKKQAYVIIALTSFLFVFFFSHSLLEILDFDWSIFLHDVEKTEK
                     FVFLLLVFSMSMTCLLALFWRGIEELSLRKMQANLKRLLAGQEVVQVADPDLDASFKS
                     LSGKLNLLTEALQKAENHSLAQEEEIIEKERKRIARDLHDTVSQELFAAHMILSGISQ
                     QALKLDREKMQIQLQSVTAILETAQKDLRVLLLHLRPVELEQKSLIEGIQILLKELED
                     KSDLRVSLKQNMTKLPKKIEEHIFRILQELISNTLRHAQASCLDVYLYQTDVELQLKV
                     VDNGIGFQLGSLDDLSYGLRNIKERVEDMAGTVQLLTAPKQGLAVDIRIPLLDKE"
     gene            complement(64768..65466)
                     /gene="liaF"
                     /locus_tag="ACL3EZ_000842"
     CDS             complement(64768..65466)
                     /gene="liaF"
                     /locus_tag="ACL3EZ_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein
                     LiaF"
                     /protein_id="HGR0392441.1"
                     /translation="MRKFKIFLFIEACLLTGALILMVSEHFSRFLLILFLFLLLIRYY
                     TGKEGNNLLLVAVTILFFFIVMLNPFVILAIFVAVIYSLFLLYPMMNQEKEQTNLVFE
                     EVVTVKKEKNRWFGNLHHFSSYQTCQFDDINLFRFMGKDTIHLERVILTNHDNVIILR
                     KMVGTTKIIVPVDVEVSLSVNCLYGDLTFFNQPKRALRNEHYHQETKDYLKSNKSVKI
                     FLTTMIGDVEVVRG"
     gene            complement(65543..66553)
                     /gene="fni"
                     /locus_tag="ACL3EZ_000843"
     CDS             complement(65543..66553)
                     /gene="fni"
                     /locus_tag="ACL3EZ_000843"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004452 - isopentenyl-diphosphate
                     delta-isomerase activity [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HGR0392442.1"
                     /translation="MTTNRKDEHILYALEQKSSYNSFDEVELIHSSLPLYNLDEIDLS
                     TEFAGRKWDFPFYINAMTGGSNKGREINQKLAQVAESCGILFVTGSYSAALKNPTDDS
                     FSVKSSHPNLLLGTNIGLDKPVELGLQTVEEMNPVLLQVHVNVMQELLMPEGERKFRS
                     WQSHLADYSKQIPVPIVLKEVGFGMDAKTIERAYEFGVRTVDLSGRGGTSFAYIENRR
                     SGQRDYLNQWGQSTMQALLNAQEWKDKVELLVSGGVRNPLDMIKCLVFGAKAVGLSRT
                     VLELVETYTVEEVIGIVQGWKADLRLIMCSLNCATIADLQKVDYLLYGKLKEAKDQMK
                     KA"
     gene            complement(66537..67544)
                     /locus_tag="ACL3EZ_000844"
     CDS             complement(66537..67544)
                     /locus_tag="ACL3EZ_000844"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000562378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004631 - phosphomevalonate kinase
                     activity [Evidence IEA];
                     GO_process: GO:0016126 - sterol biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HGR0392443.1"
                     /translation="MIAVKTCGKLYWAGEYAILEPGQLALIKDIPIYMRAEIAFSDSY
                     RIYSDMFDFAVDLRPNSDYSLIQETIALMGDFLAVRGQNLRPFSLEICGKMEREGKKF
                     GLGSSGSVVVLVVKALLALYDVSVDQELLFKLTSAVLLKRGDNGSMGDLACIVAEDLV
                     LYQSFDRQKVAAWLEEENLATVLERDWGFSISQVKPTLECDFLVGWTKEVAVSSHMVQ
                     QIKQNINQNFLSSSKETVVSLVEALEQGKSEKIIEQVEVASKLLEGLSTDIYTPLLRQ
                     LKEASQDLQAVAKSSGAGGGDCGIALSFDAQSTKTLKNRWADLGIELLYQERIGHDDK
                     S"
     gene            complement(67531..68484)
                     /gene="mvaD"
                     /locus_tag="ACL3EZ_000845"
     CDS             complement(67531..68484)
                     /gene="mvaD"
                     /locus_tag="ACL3EZ_000845"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0004163 - diphosphomevalonate
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HGR0392444.1"
                     /translation="MDREPVTVRSYANIAIIKYWGKKKEKEMVPATSSISLTLENMYT
                     ETTLSPLPANVTADEFYINGQLQNEVEHAKMSKIIDRYRPAGEGFVRIDTQNNMPTAA
                     GLSSSSSGLSALVKACNAYFKLGLDRSQLAQEAKFASGSSSRSFYGPLGAWDKDSGEI
                     YPVETDLKLAMIMLVLEDKKKPISSRDGMKLCVETSTTFDDWVRQSEKDYQDMLIYLK
                     ENDFAKIGELTEKNALAMHATTKTASPAFSYLTDASYEAMDFVRQLREKGEACYFTMD
                     AGPNVKVFCQEKDLEHLSEIFGHRYRLIVSKTKDLSQDDCC"
     gene            complement(68466..69344)
                     /gene="mvk"
                     /locus_tag="ACL3EZ_000846"
     CDS             complement(68466..69344)
                     /gene="mvk"
                     /locus_tag="ACL3EZ_000846"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004496 - mevalonate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0016126 - sterol biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HGR0392445.1"
                     /translation="MTKKVGVGQAHSKIILIGEHAVVYGYPAISLPLLEVEVTCKVVP
                     AESPWRLYEEDTLSMAVYASLEYLDITEACIRCEIDSAIPEKRGMGSSAAISIAAIRA
                     VFDYYQADLPHDVLEILVNRAEMIAHMNPSGLDAKTCLSDQPIRFIKNVGFTELEMDL
                     SAYLVIADTGVYGHTREAIQVVQNKGKDALPFLHALGELTQQAEVAISQKDAEGLGQI
                     LSQAHLHLKEIGVSSPEADFLVETTLSHGALGAKMSGGGLGGCIIALVTNLTHAQELA
                     ERLEEKGAVQTWIESL"
     gene            complement(69466..69795)
                     /locus_tag="ACL3EZ_000847"
     CDS             complement(69466..69795)
                     /locus_tag="ACL3EZ_000847"
                     /inference="COORDINATES: protein motif:HMM:NF024736.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGR0392446.1"
                     /translation="MIRKAYDTDLNDQEWAKIEPYFSKHRTYKWPKRVLVNDTLYVTK
                     TGCQWRMLPHDFPLYLMVWSFFRRSMTTGWFQVNGRWYYAYSSGALAVNTTVDGYSVN
                     YNGEWVQ"
BASE COUNT        20652 a        15764 c        12658 g        21001 t
ORIGIN      
        1 tactgggatt gggggtcgtt taggggcggt cattttagcc gagattcgaa atattcatgc
       61 ctttgataat cctgctcaat tacaagcttt cgctggactg gattcttcta tttatcagtc
      121 aggtcagatt gatttagcag gaagaatggt caaacggggt tcccctcatc tgcggtaggt
      181 actcatacaa gctgccaaag catgccctcg cttttcacct gcttttaagg cctatcttaa
      241 gactaagtta gaacaaggaa aacattacaa tgtagccatc atccaccttg caaaaaaact
      301 tatccgaacc ctgttttata tcctaaaaaa gagctgccat ttgacgaaca aaaagtgatg
      361 taatttctga aattaacaca ggattacctt tgaaaaaatg gactttttca agggcttttt
      421 gccgtgctct aaaatcatcg ccaaatcatc aaattgaaat aagaagtagt ttagataaaa
      481 ctattgactt ttcttatagt ttgtctttct tctatcttcc attatatcat actttttcag
      541 tctatggtag ctctctttaa aaggctccga tactgccgcc acctccgcct ccagagaagc
      601 caccgccaga acttccactt ccagaagata cggagtaggt acttgctgta tttgcgacac
      661 tagcataatg gctcatttgc gcgcttgaat gataaaacat actgtgccag ccataagcta
      721 catagagatt gatatctgga ttttcaactt gaatctgatg aaccttcatc aaatgactaa
      781 ccttgtccgc atagccaaat aaggttgcat agaccaagag acgattccaa acaacaatac
      841 tttccaattc agccttatcc agtcgtgcaa tctcacgtaa catattttca aaactggtcc
      901 agagatagta gacctcagct cccgcttcat ttagaacacc atcacgatta tctagtcgaa
      961 gcttccaata atagaaaaca gacaaaacta accctagaaa accaagtatt ggcaaaggga
     1021 ggtaaagata gccatgaacg tctaaactgt acaagaacaa accaaatccg ataaataggg
     1081 gcaagatagt caagacaccc atacccactt gcaaagcctt ttccaaacca gttaaaggac
     1141 gatagtaatc tgggagtccc cagaagacaa ctcgctttct cactccttct tgcatctggt
     1201 tcaatacctc ttcaaaagaa gatttgagct gaatccctct tgcttgaatc cgtttctcat
     1261 cagcagcttt agctccgcga taaaggctgt cagatacctt gtaatccgca aacaaattgg
     1321 aaagagtggc ttcttttttg cctgaaaagg ctagatttag acagtctctc tcaaatcttg
     1381 acaaaccatc ttctttcacc aatctcaagc caactgcatc tccttctgaa ataatagaaa
     1441 cattcccacg gtccatcaca tctagcaagg tagcttgaat aagttggtca aaagtgaatt
     1501 tgccagcccc cttgactaag ggactcactt cctccaagga ggtcgagtag acagcctctg
     1561 ataaaaccat aggctctaat tccattggtg gttcatagag acgatgattt ttggcatatt
     1621 tgactgaagg agtggtcttt cttctataaa taaaatagaa gcagacactc aataacaagg
     1681 agatagaaag gatcgaaggg aggacccaag taacaagttg tttactctga tctttttctc
     1741 taacaatcga gtcttctatc ttattaaact cttctaaacg attccctttc aatccctgat
     1801 ccctagcgct agcaaaatcg gtccgaggcc agtaggcatg caactcaact ccacgcttag
     1861 ccggaagatt gtctaaacgg atagtataat caaggttact cttttcaatc gttccctctc
     1921 taaaaagttt ccctgtatgg aaaaagagtt tttcagcccc cttgtctccc cttacatgaa
     1981 attcaaactt ttcaatagac tctgaactat ctgtcagagg ttgccaattt aattcagcaa
     2041 tatcatcata aaggaaaagt aaatttttta agttccagac gaggtcaact tcaactatgt
     2101 cgccctcctg acctggatta tagactctca cagtataacc atccgcttct tctgttactt
     2161 cgctagtcac atctgctagt tctgcaccgt ttttcgcggc ctgaaccttt ggatgagggt
     2221 caatgtcaaa cccgctaggc atcttaccag cacgtccaag tcccacgatt tgtcccttaa
     2281 agtcctcctc aaactggtaa actatcttct gtctaaactc tgccgtatta tctgcatgaa
     2341 tatacaaatc cccttgataa gagtttatct tgaaatcaat ggcaaaaaca gagagtggaa
     2401 gaaggcaaaa caagcctaac accagtaaga aaaaagtttt tttcatcaac taagccccct
     2461 ttttatcttt cttatcatta tagcattttt tcgtaagtaa aggcttactt atgttgaaaa
     2521 attacgcatt tttcgataaa ataggagaca gttatttttt aatagatcag aataggagaa
     2581 atcatgagaa aaatatactt atctattttc acaagtctct tgctgatgct aggacttgtc
     2641 aatgttactc aagccgatga atatttacgc atcgggatgg aagcagcata tgctcccttt
     2701 aactggaccc aggatgatga tagcaacgga gctgtcaaaa tcgatgggac caatcagtat
     2761 gccaacggat acgatgttca aatcgccaag aaaatcgcta aggacttagg taaagaacct
     2821 ttggttgtta aaaccaagtg ggaaggtcta gtccctgccc ttacttctgg taagattgac
     2881 atgattatcg caggtatgag tccaactgca gaacgcaaac aagaaattgc cttttcgagc
     2941 agttactaca ctagcgaacc agttttgctt gtcaaaaaag attctgccta cgcaagtgct
     3001 aaatctttgg atgactttaa tggtgcgaaa atcacttctc aacaaggtgt ctacctctac
     3061 gacttgattg cacaaatccc aggtgctaaa aaagaaacag ccatgggaga cttcgctcaa
     3121 atgcgccaag ctcttgaggc tggtgtcatt gatgcttatg tttctgaacg tccagaagca
     3181 ctgactgctg aagctgcgaa ctctaagttc aagatgattc aagtagaacc tggtttcaaa
     3241 actggggaag aagatacagc tatcgctatc gggcttcgta aaaatgacaa tcgtattagc
     3301 caaatcaatg ccagcattga aaccatttca aaagatgacc aagttgcctt gatggatcgt
     3361 atgatcaagg aacaacctgc cgaagctaca acaactgaag agactagcag tagtttcttt
     3421 agccaagtcg ctaaaattct ttctgaaaac tggcaacaac tcttgcgtgg tgctggtatc
     3481 actcttttaa tctctatcgt cggaaccatc ataggtctca ttattggact tgccattggt
     3541 gtcttccgta ctgctcctct ctctgaaaac aaagccattt atggccttca aaaactagtc
     3601 ggctgggttc tcaatgtcta cattgaaatt ttccgtggta cgccaatgat tgttcaatcg
     3661 atggttatct actatggaac tgcccaagct ttcgggatca accttgaccg tacactggct
     3721 gctatcttca tcgtttcaat caataccggt gcctacatga ctgaaatcgt ccgtggtggt
     3781 atcctagcag ttgacaaggg acaatttgaa gctgcgactg ctcttggtat gacccataac
     3841 cagaccatgc gtaagattgt cctacctcag gtagtccgta acatcctacc tgcaactggt
     3901 aatgaatttg tcatcaatat caaagataca tctgtattga acgttatctc tgttgtcgaa
     3961 ctttatttct caggaaatac cgtggcaaca caaacctatc aatacttcca gacatttaca
     4021 atcatcgccg tgatttactt tgtcctcacc ttcaccgtaa cacgtatcct acgatttatc
     4081 gagcgccgaa tggacatgga tacctatact acaggtgcta accaaatgca aacggaggat
     4141 ttgaaataat gacacaagca atccttgaaa ttaaacacct caaaaaatcc tatggacaaa
     4201 acgaagtgct aaaagacatt tcactcactg tccacaaggg agaggtcatc tctatcatcg
     4261 gaagctctgg aagcggaaaa tcgaccttcc tacgctccat taacctactt gaaacaccaa
     4321 ctgatggaca aatcctttat catggacaaa acgtcctcga aaaaggctat gacctcacgc
     4381 aataccgtga aaagttgggg atggttttcc aatcctttaa cctctttgaa aatctcaatg
     4441 ttcttgaaaa cacaatcgtc gctcagacaa ctgtcctaaa acgcgaacgc acagaagctg
     4501 aaaagattgc caaagaaaac ctggaaaagg tcggcatggg agaacgctac tggcaagcca
     4561 aaccaaaaca actctcaggt ggtcaaaaac aacgtgtggc catcgctcgt gccctctcca
     4621 tgaatccgga cgctattctc tttgatgaac caacatcagc tctcgatcca gaaatggttg
     4681 gagaagtcct caaaatcatg caggacctgg ctcaggaagg cttgaccatg attgtcgtaa
     4741 cccatgaaat ggaatttgcc cgtgatgtct ctcaccgtgt tatctttatg gataagggcg
     4801 tgatcgctga agaaggtaaa ccagaagacc tcttcaccaa tcctaaagaa gaccgaacaa
     4861 aagagttcct tcaacgctat ctcaaataaa aagaaaaggc tgcatcaacc gtgcagtctt
     4921 tttgctgtcc tcaaaatgaa aaggcagatt ctctatctct actacttgaa ggtcaagaat
     4981 ccgccgttat ccaaagatta atcttcaaat ttttcataat ttttttcata gaaatcaatt
     5041 aagcctaggg ctgtttcaaa tgaaatattt tttacttttg cacgaccctg cgccagagca
     5101 atgatagaca tttcacgcgc attcgtttct ttagagatac ggtagcctgt gattttctta
     5161 tcacgaaccc agccaacaac tgattctact ttttcaaagt ttgacttagc catgtttttc
     5221 tcctattttc ttctttataa tatttaattg tatacgtttt tactactttt gtcaataaaa
     5281 aaaacatata ttcaacgaaa ataattagtt cagaattttc ttacttcctt tttaaatccg
     5341 ataatatata ggttttgcta gcctctacac cataaatatt tgctaataaa actactgtat
     5401 tattaccctc ttaaggtgcg aaattattca agttcttaaa aaatgcttct ctatttccgt
     5461 aagatagctt atttcttcga tttaagaact gaagatgata gttctaacct ttagaaatcc
     5521 aagccttcac tagctcaaaa actcctatct ttcttcctca ataaatcatc tgagagatag
     5581 gtatttctta tatccttcaa attcatcact cctttggata ttgaggtgct agcctagaag
     5641 cagacacccg attatctaaa ccatccttaa tagagatgac aagacagata agctcagtta
     5701 attacttata tatcttttta atatggtata tttgtcaaca aaaagaaatc aaatcatacc
     5761 ttatactcaa tgaaaatcaa agagcaaact aggaagctag ccgcaagttg ctcaaaacac
     5821 tgttttgagg ttgcagatag agctaacgtg gtttgaagag attttcgaag agtattaaag
     5881 acagtgtgac tatgcttgtc aatagatagg aaatcaaaat gaaggatgga aatctgagcc
     5941 aaacatcata agtgctataa tgaacagaag taagaattgc acgataagtt ttctaaaacc
     6001 ataggaatcg tcccctttct tcatcttcat tatagcatat atacatcagt tgtacaaata
     6061 atatgatatt tttttattag tcctcagaca agcatattat aaagcgtttc attaccattt
     6121 aagttaatat aagctggatc aaaaccttcc attctacgaa tcaaacctgc ataatcatgc
     6181 ttatctgcta aagcgatccc aatcaatact gggcctgttc ccttgctagc tcgtttgata
     6241 tactcaaaac gtgtgatatc atcatttggc cccaggatat catttacaaa ctcacgcaaa
     6301 gctcctggac gttgtgggaa attgaccaca aaataatgtt tgataccatc ataaatcaag
     6361 gcacgctctt ccatttctgg catacggttg atatcattat ttcctccaga aatgatacaa
     6421 caaatggttt tccccttaat atattcagct aaaacctcta aagaggcgat actagctgct
     6481 ccagcaggtt ctgcgactat cccttgctta gagtaaaggt caatcaaggt ttcagaaatc
     6541 aatccctcat cgacacctac caaagtttga atatgttgac gagttgcttc ataggtcaac
     6601 tgacctacct tttgcacagc aatcccatcc gcaaatttat caatttcctt gagtttgact
     6661 ggacctccag cctcaaaggc agctttcatg gaacgcgctc cattcgcctc tactccgata
     6721 acctcaatct ctggacttgt ttccttgata taggtagaaa ccccggcaat gagaccgcca
     6781 ccaccaacag gaaccaagac agcatcaaaa tcaatcgatt cttttcgagc ttcttctaaa
     6841 atctcataag caactgttcc ttgacctgct tgaacatgag catcatcaaa aggatcaata
     6901 aaggtacgat tttcagagac tgtaaattct tgagctgctt tggctgaggc atcaaaggta
     6961 tctccaacta gtttaatagt tacaaaatcc ccaccaaaaa agcgaacctg accaatcttt
     7021 tgttgtggcg tagtaatggg cataaagata gtagcaggaa ttttcatttc attacaagta
     7081 taggctactc cctgcgcatg atttcccgca gaagcgcaaa ctaccccacg ttcacgttct
     7141 tccttgctga gctgggaaat ggcataatag gcaccacgaa ttttaaagga gcgaacacgc
     7201 tgggcatttt cttttttcaa ataaatctta gcaccatact tctccgataa ataatgatcg
     7261 taatccagtg gagtattcac aaccacaccg ttcaagacct tgtgagcctt gattatatct
     7321 tttgaactta acatataaaa cctctttttc tataaaaaac agtcactaat gactgttttt
     7381 tagttattca tctccgaaaa tttcagtaac actttcatgg tatttatgag ccatacgaat
     7441 cgaaaactct ttaggaagtt cataacgatt tgtggaaatc caatcatata accattctac
     7501 caaactttct tcactatcat tacgatggaa gataaaatag tttaaaattt ctttatattc
     7561 tacatcattc aaatccaacg tgtctacaaa ttgactacga ggaacaaaat tagaatctaa
     7621 ttttcttagt tgatctgtca attctcccaa ttgtaaatcc aactgaaaaa atagtttttg
     7681 cagttgccta tcagtttcat cacatcctgt cttgatagaa aacaaattgg taatattcat
     7741 atgatttcaa cccctaaata agtacatcta atatcccacg aatagctgaa gctaaagttt
     7801 tcgcagtcca gtcatttaaa cccgattctt tcaatccaga tgcaataatt tgctctattt
     7861 gatataaacc gccatctatc gtctcattta ttctgcgaag aggaccttca atataggata
     7921 aagcttctcc gaatctaaca gctgatttag gtcctaatga tttaccaact atatttgtta
     7981 atatttttta tttctcaaaa tccatttcgc tatataacga gcagatttag tcgcaccagc
     8041 tctctcaaac ggagaatgaa tttcaagacc ttcttctcta gctatttgtg ccaatttgaa
     8101 gaattgttca aaggtcatat gcaacctacc atcttcaaaa ttagcatcat cataaatgtt
     8161 aattacagca ttttcatcat acgaccaatc tgctttattt tggtctgcta gcactattac
     8221 cgacggtgta attacattat acaactagaa ccaataataa cgatgcaatt tttctcataa
     8281 tctttttcat aaaatcatct ccagcgctat atatttctaa ttagttatag attttgaatg
     8341 catcatcgtc gtttttacca acgaatggca ttgctttacg caattctgca ccaacttttt
     8401 caatttcaag gttagctgct tgttcacggt aagcagtcaa ttttggacgt ccagctttat
     8461 agtcatttac aaagtcattt gcaaatttac cattttggat gtctgccaag acagccttca
     8521 tattttcttt aacttgttca gtgattacac gtggacctga tacatagtca ccgtattcag
     8581 cagtgtttga aatagattga cgcattttct tgaatccacc ttcgtagatc aagtcaacga
     8641 tcaatttcat ttcgtgaaga acttcaaagt aagccaattc tggagcgtaa cctgcttctg
     8701 tcaagacttc gaaacctgct tcgataaggg cagtcaaacc accacaaagt acagcttgtt
     8761 caccaaacaa atcttcttca gtttcttctt tgtaagttgt ttcaagaaga cctacacgag
     8821 ccgctccaac acctttacac cagtccatag caatgttttt agcatttcct gttgcatctt
     8881 ggtatactgc ataaagagct ggaacaccaa atccttcttc gtaagtacga cgtaccaagt
     8941 gtcctggtcc tttaggagca cacatgaaga catctacatc cgcaggaact ttgataaatt
     9001 caaagtggat gttgaaacca tgggcaaatc caactgcgtt tccagcttcc aagtttggag
     9061 cgatttctgc ttcgtacaat tcttgttgaa tttcgtctgg cgccaagatc atgataacat
     9121 cagccaactt agtagcttct gctactgtgt aagtatcaaa tccatcttct tttgctttat
     9181 caaaagattt acctggacgt acaccgataa taacgtcacg acctgaatca cgcaagtttt
     9241 gagcatgcgc atgcccttgt gaaccataac cgataacggc gattttttta ccgtcaagtg
     9301 ctgctacttt aacatctttt tcatattcca tttgaactgt catagctttt ctctcttttc
     9361 tattatttat tgccttttaa gctggtttaa caaatttaag ttggattttt aatcgcgggt
     9421 aaatccagtt gcacccgttc gagcaatatt gcgaataccg tatgggcgaa tgactcgcaa
     9481 tagggcttcg ctcttttctg catttcccgt catctgaatg gtaatcgagc ttggcgctac
     9541 gtctaccact gttgcacgga aaggttgaat aatcgctaaa atctcagctc tcttctcagc
     9601 tggcgctgac atcttaacca aaatcacctc gcgctccaaa tgaggcttgt ctgtaatatc
     9661 tcgaatgcga atcacatcaa tctgacgatt gagctgtttg atgatttgct ccacttcatc
     9721 atgagaagca acatcaataa taatagtgat acgcgataca ttcggatctt ctgttgctcc
     9781 aacagagatg ctttcaatat taacctgacg acgagatagg acacctgtaa agcgattgag
     9841 gactcctgaa cgattttgta gttttgctgt taacattcta cgcatggaac tgcaccccca
     9901 acatctcatg attactctta ccagccggta ccattggtaa cacctgttcc ttacgagaaa
     9961 tatctacctc aattagcata ggaacatcct cagtgatgac ttcaaggtct tgagccaagg
    10021 tctcaggatt gtcaaactta tagtttttaa taccataagc ctgcgccatc aattggaaat
    10081 caggaagggt atcaaagacc gactctgatg ttctgccttc atagaaggat tcctgccact
    10141 ggcgaaccat tccgagtgaa tgattgttca gcataaccac cttgattggc accttgtaaa
    10201 tattcaaaat agccaactcc tggttggtca tttggaaacc accatcccca acaaacaaga
    10261 ctacttcctt atctgggtta gcaattttag caccgattgc tgctggaatt ccaaagccca
    10321 ttgttcccaa accacctgaa gtcactaact gacgttcatt ttggtaggga taatactgag
    10381 ctgtccacat ttggtgttga ccaacgtctg ttaccacaat ggcatctcca ttcgtcaatt
    10441 caccaattcg ttcaataact gcttgcggtt gaaccacacg ctctttcttg tcatacgaac
    10501 gaacacgatt cttgtcttta gtgactttct caatccactt ttcagtattg ttgtgaactg
    10561 ttggttctgc tagcaacatt tgcaaggcct tcttagcatc tccaactaca ggaatgtctg
    10621 cactgataat cttgccaatc tcagctgggt caatatcaat gtgggcaacc ttagcattct
    10681 tagcgaaagt cttaggattc cccgtcaaac ggtcatcgaa acgagaacca atactaatca
    10741 taaagtccgc ttccgtcatg gcaatatttg ctgcgaatga cccgtgcatg cctcccattc
    10801 caagaaagag tgggtgactc gttgcaatcg ttccttgtcc caaaagactg gttaccactg
    10861 gaatttgata gcgttctgca aattcattta gttccgtagc agcctcagca taactaattc
    10921 caccaccagc taacaagact ggctttttag ccttggacaa ttgcttcaag attttcttga
    10981 tttgcatatc attcggctca agagtcggct gataacttgg taaattcact tctggtgaat
    11041 aaatgaagtc tgtttctaaa gcagatatgt cttttggtag gtcaattaca actggccctg
    11101 gacggcctgt agttgcgata tggacagctt ccgtaatgat acgcggaata tcagctgtct
    11161 cacgaacttg gtaattgtac ttagtgattg gcatggtaat tcctacgatg tctgcctcct
    11221 gaaaggcatc cttcccaatc cctgctcgcg ccacctgacc tgtaaagacc aaaaggggaa
    11281 cgctatcgct catagcatcc gcaatccctg taatggcatt tgttgctcct ggtccactag
    11341 tgacgacggc aacacccaac tttccagttg atttggcata gccttcagct tcatgcaaac
    11401 aaccttgctc atggcgccct agaatgtggc gaatgccttt aaaattatat atcgcatcat
    11461 aaaaaggcaa aaccgcacca ccaggataac caaagatggt atcaactcct aaatcacgaa
    11521 gtgtttccaa aactaggtcc gaccccgtct taggagattc taaactgatt ttctccatta
    11581 ttcccctttc tttcctctta aaaataactt gttactatca taccattttt tcaaaatttt
    11641 tcaagataaa agaagaaatt ttctgaattt tctattttaa cgtttattta tgaatgttat
    11701 ttttgttttt attaaaaaga taccgatttc atttactaaa aagaaaaaag aactgatttc
    11761 tcagtccttc attaatctta ttccacacta aataggtatg ggtaaacagg ttgttgacct
    11821 tggtgaatct cgacttcaac gtcttcgaat tcttctacga tttcttgagc gatttcattg
    11881 gcaagttctt cgcttccgtc ttcaccgaca tagaaggtta cgatttcact gtcttcatcc
    11941 aacatatgtt tcaaggtttc agtcaatgtt tggtgcatat cagggtttga cacaagaatt
    12001 tttccatcca ccatacctaa attatcgttt tcatggattt ctaagccatc gatcgttgta
    12061 tcacgcacgg ctgttgtgac gcttccgcta acgacatcgc taagagcagc tgtcatacgc
    12121 tcttggtttt cttcaatgga cttgcttgga tcaaaggcaa gaagacttgt cataccttga
    12181 ggaagagtgc gagcctctac cactaccgct ggttgctcca aaacttctgc cgcagattga
    12241 gctgccatga agatgttctt gttgtttggc aagaagatga tgttacgggc attaacctgt
    12301 tcaacagcct tgataaagtc ttctgttgaa gggttcatgg tttgaccgcc ttcgataaca
    12361 taatccacgc cttgagaaca gaagatatct gctagacctt taccagccac cacagcaatc
    12421 aaagcatact ctttttcttc agccgacttg ataacttgag tagcttcttt ctcaacctgt
    12481 gcttcgtgtt ggttacgcat attgtcaact tttaccttga ccaagctacc atatttgaga
    12541 ccttcttgca taacaagtcc tggatcttct gtatgaacat ggactttgac aatttcatca
    12601 tcgttaacaa cgaggagaga atctccaagc tcatccaagt agttacggaa ttcatcgtag
    12661 tcaaaatctt tagcataggt tggaccttgc ttaagagcta ccatgatttc agtacagtaa
    12721 ccaaacgtga tgtcctcagt cgctacgtga ccagctacag acttatgatg ctctacattg
    12781 atcatctcac tcatgttggc aggagtcgct acaaagtcct cagatgcaat atattcgcca
    12841 gtaagggctg aaaggaaacc ttcgtagatg aagaccaatc cttgaccacc tgagtccaca
    12901 acgccaactt ctttcaatac tggaagcatg tctggtgttt tagctagagc tgttttagca
    12961 ccttccaagg ctgcgctcat gacttcaaca gtgtcatctg tttgctcagc ttttttctta
    13021 gcaccgatag cagctccacg agaaactgtc aaaatcgttc cttcaacagg tttcatcact
    13081 gccttatagg caacttccac acctgattgg aaggccagag ccaagtcttg acctgttaac
    13141 tcgtctttat ccttgatagc ttgggaaaat ccacggaaaa gctgagacgt aatcactcct
    13201 gagttcccac gcgcacccat caaaagccct ttggcaagaa tgctcgctac ttctccaact
    13261 gtagaagctg gcttgtctgc aacttcttta gcaccatttt caatggtcat tcccatattt
    13321 gtcccagtat ctccatctgg aactggaaag acgtttaatg aattgacata ttcagcttgc
    13381 ttattcaagc gagttgatgc agcctgcacc atttcttgaa ataagctagt agtaattttt
    13441 gacacggtta ttctcctaca actttgatat tttgaatgta gacatttaca gtctgagcag
    13501 taattccaag ctggttttcc aagctaaagg caacacgctc ttgaatgttt tttgacactt
    13561 cactaatctt tgttccgtag cttaacacag tatatacatc aactgcaata ctgccatctt
    13621 cggctgcctt tacgacgaca cctttagaat aattttcttt acctagcagg gcttggaaat
    13681 tatctttgag ggcattttta ctagccatac cgaccacacc aaaaatctca gttgctgctc
    13741 cacctacgac ggttgcaatc acttcatctg ttagttcgat ttgaccatct tttgtattaa
    13801 tttttacagt catccttttt acctcaacta gttgatactc tattttatca tatttcagcc
    13861 caagtgtaaa agcagaataa tgtatcagcg gatatttact ctatttttca aacgatgtta
    13921 tacccacaat aaaagaaaaa agaccctaag gtctcctttg cttttattat taaacgcgtt
    13981 caactttacc tgatttcaaa gcacgagctg aagcccaaac ttttttaggt ttaccatcga
    14041 taagaacagt aactttttga aggtttggtt ttacggcacg ttttgtttgg ttcatcgcgt
    14101 gtgaacggtt gtttcctgat acagtcttac gacctgtaaa gtaacatact ttagccattg
    14161 tgttttcctc ctattagatc taatatagcg gatgtgctag caccacatac cgtactatgt
    14221 tatcacactt tcttgttttt tgcaagggaa ttggaagatt ttttatttgt gtcttaaatc
    14281 aggtcttgcg tgatattttc tgctctccac atgccattgt tgattaacag aacaccagaa
    14341 ttaaaattat gtgtataaaa atcatctcta actgcagcta agggtatagc cgtcaagtcc
    14401 aaatcccaca gctcatctat cgattttctt acaacaatat ctgaatccaa atacagtaca
    14461 cgagactcgc ttacatactt tggaataaaa tacctaaaaa aagccgcata tgaaagtccc
    14521 tcaaagggga gacgataacc tttcagaata ctactgtcaa tctgaacatt cacaatctca
    14581 ctattcaaag tctctagtct tttttccatc aattggaacc attctcgcgg aaggtcatca
    14641 ttaaaaacat aaaacttaag attataatga tgaacacaaa gagattttat tgttgtttca
    14701 actttatcca tataagcatt atctgcacct aagacaatcg cttttttctc ttctttcact
    14761 ctttatctta tttcttttta ttcccatcat attattccca tcatatgttt ctacgtaacc
    14821 attattttcg cctattcgtt cgtaaaacca taccagtgga gattttagat gaagtcccat
    14881 tacggtttac aatttttaca ttacgacacg gagttttaca aatcgatttc atttgccaaa
    14941 cgtagttagt aaggcagtta gctaggctac ctactttctg ctacgacgga aaaatccaca
    15001 aatcaatacc attcgtggat ttttcctagt gaagcgttta ggtaagccgc catagcggtt
    15061 accgattatt atattacgac acggagtttg gcaaatcgat tctatttgcc aaacgtagtt
    15121 agtgaggcag ttagctagtt cgccaaatag cgactagcgt ccaacaattt ggaactttag
    15181 ttccaattgt tggtactgag tcacatcttc tcctctaact ctacgtctgg atacttgtcc
    15241 gcaaaccagc ggagggcaaa gtcattttca aagagaaaga ctggttggtc aaaacggtct
    15301 ttggctaaga tattgcgact tgacgacatc cgttcatcca agtcctcagg cttgatccaa
    15361 cgaacggtct ttttacccat tgggttcata actacttctg cattgtactc gccttccatg
    15421 cggtgtttaa agacttcaaa ctggagttga cctacagcgc ctagcatgta ctcacctgtt
    15481 tggtaattct tataaagctg aacggctcct tcttgcacca attgctcaat ccccttgtgg
    15541 aaggattttt gcttcataac attcttagca gaaactttca tgaaaatttc aggagtaaag
    15601 gttggcagtg gttcaaattc aaacttgttt ttaccaactg tcaaggtatc cccaacttga
    15661 taagtaccgg tatcgtaaac cccgataata tcacctgcca cggcattgat cacattctca
    15721 cgactttccg ccataaactg agtaacatta gacagtttag cccccttacc agtacgaggg
    15781 agattgacac tcatgccgcg ctcaaattcg ccagatacga tacggacaaa ggcaatacgg
    15841 tcacggtgac gagggtccat gttggcttgg attttaaaga caaatcctga gaaatccttg
    15901 tcataaggat ccacaatttc accgtctgtt ttcttgtgac catgtggttc tggagcaaac
    15961 ttgaggaagg tttcaaggaa ggtctgcaca ccaaagtttg tcagggctga accgaaaaag
    16021 acaggcgtca attctccagc cagaatagct tcctctgaaa actcattccc ggcttcattt
    16081 aaaagctcaa tgtcatcctt gacttgctcg tagaaaggat tgctaccaaa gagtttgtcc
    16141 ccgtcttcta gactggcaaa acgctcatcc cctttgtaaa gctctaaacg ttggttatag
    16201 aggtcataca agccctcaaa ggctttcccc atcccgatag gccagttcat agggtagcta
    16261 gcaatgccca agatttcttc caattcttgc aagagatcca aaggctcacg accgtcacgg
    16321 tccagcttgt tcataaaggt aaagactgga atgccacgat gtttcacaac ctcaaacaat
    16381 ttcttggttt gagcctcgat ccccttggca gagtccacga ccatgaccgc agcatccacc
    16441 gccatcaagg tacgataggt atcttctgag aagtcctcgt gccctggcgt gtctaagata
    16501 ttcacgcgct tgccgtcgta gtcaaattgc ataacagatg aagtaacaga aatcccacgt
    16561 tgcttctcga tatccatcca gtcagattta gcaaaagtcc ctgttttctt cccttttacc
    16621 gtaccagcct cacgaatctc acccccaaag tagagtaact gctcagtgat ggttgttttc
    16681 cccgcgtccg ggtgggagat aatggcaaag gtacgacgtt tcttaatttc ttcttgaata
    16741 ttcataagtt ctctttcttt gattctctat ttttcttgtt tcaatagctg agaatgattt
    16801 ttacattgga ttttaccatt cctttcaaca ctccattata tcggatttta gcattttttt
    16861 caatttctat ttcttttcac ttccccctcc cttatttata ggaaaatatg gtaaaataga
    16921 acagactaaa aatcatcatt tcacgaaagg atgcaagatg aaaattacgc aagaagaggt
    16981 aacacacgtt gccaatcttt caaaattaag attctctgaa aaagaaactg ctgcctttgc
    17041 gaccaccttg tctaagattg ttgacatggt tgaattgctg ggcgaagttg acacaactgg
    17101 tgtcgcacct actacgacta tggctgaccg caagactgta ctccgccctg atgtggccga
    17161 agaaggaaca gaccgtgatc gcttgtttaa aaacgtacct gaaaaagaca actactatat
    17221 caaggtgcca gctatcctag acgatggagg agatgcctaa tgacttttaa caataaaact
    17281 attgaagagt tgcacaatct ccttgtctct aaggaaattt ctgcaacaga attgacccaa
    17341 gcaacacttg aaaatatcaa gtctcgtgag gaagccctca attcatttgt caccatcgct
    17401 gaggagcaag cccttgttca agctaaagcc attgatgaag ctggaattga tgctgacaat
    17461 gtcctttcag gaattccact tgctgttaag gataacatct ctacagacgg tattctcaca
    17521 actgctgcct caaaaatgct ctacaactat gagccaatct ttgatgcgac agctgttgcc
    17581 aatgcaaaaa ccaagggcat gattgtcgtt ggaaagacca acatggacga atttgctatg
    17641 ggtggttcag gtgaaacttc acactacgga gcaactaaaa acgcttggga ccacagcaag
    17701 gttcctggtg ggtcatcaag tggttctgcc gcagctgtag cctcaggaca agttcgcttg
    17761 tcacttggtt ctgatactgg tggttccatc cgccaacctg ctgccttcaa cggaatcgtt
    17821 ggtctcaaac caacctacgg aacagtttca cgtttcggtc tcattgcctt tggtagctca
    17881 ttagaccaga ttggaccttt tgctcctact gttaaggaaa atgccctctt gctcaacgct
    17941 attgccagcg aagatgctaa agactctact tctgctcctg tccgcatcgc cgactttact
    18001 tcaaaaatcg gccaagacat caagggtatg aaaatcgctt tgcctaagga atacctcggt
    18061 gaaggaatta acccagaggt taaggaaacc attctaaatg ccgctaaaca ctttgaaaaa
    18121 ttgggtgcta ttgtcgaaga agtcagcctt cctcactcta aatacggagt tgccgtatac
    18181 tacatcatcg cttcatcaga agcttcatca aacttgcaac gctttgacgg tatccgttac
    18241 ggctatcgcg cagaagatgc aaccaacctt gatgaaatct atgtaaacag ccgaagccaa
    18301 ggttttggtg aagaagtgaa gcgccgtatc atgctgggta ctttcagtct ttcatcaggt
    18361 tactacgatg cctactataa gaaggctgga caggtccgta cacttatcat tcaagatttc
    18421 gaaaaagtct tcgcggatta cgatttgatt ttgggtccaa ctgctccaag tgttgcctat
    18481 gacttggatt ctctcaacca tgacccagtt gccatgtact tagccgacct attgaccata
    18541 cctgtaaact tggcaggact gcctggaatt tcgattcctg ctggattctc tcaaggtcta
    18601 cctgtcggac tccaattgat tggtcccaag tactctgagg aaaccattta ccaagctgct
    18661 gctgcttttg aagcaacaac agactaccac aaacaacaac ccgtgatttt tggaggtgac
    18721 aactaatgaa ctttgaaaca gtcatcggac ttgaagtcca cgtagagctc aacaccaatt
    18781 caaaaatctt ctcacctact tctgcccact ttggaaatga ccaaaatgcc aacactaacg
    18841 tgattgactg gtctttccca ggagttctac cagttctcaa taaaggggtt gttgatgccg
    18901 gtatcaaggc tgctcttgcc ctcaacatgg acatccacaa aaagatgcac tttgaccgca
    18961 agaactactt ctatcctgat aaccccaaag cctaccaaat ttctcaattt gatgaaccaa
    19021 tcggatataa tggctggatt gaagtcaaac tagaagacgg tacgaccaag aaaatcggta
    19081 tcgaacgtgc ccacctagag gaagacgctg gtaaaaacac ccatggtaca gatggctact
    19141 cttatgttga cctcaaccgc caaggggttc ccttgattga gattgtatct gaggcagata
    19201 tgcgttcgcc agaggaggcc tatgcttatc tgacagccct caaggaagtt atccagtacg
    19261 ctggcatttc tgacgttaag atggaagaag gttctatgcg tgtggatgcc aacatctccc
    19321 ttcgccctta tggtcaagaa aaattcggta ccaagactga attgaagaac ctcaactcct
    19381 tctcaaacgt tcgtaaaggt cttgaatacg aagtccaacg ccaggctgaa attcttcgct
    19441 caggtggtca aatccgccaa gaaacacgcc gttacgatga agcgaataaa gcaaccattc
    19501 tcatgcgtgt caaggaaggg gctgcagact accgctactt cccagaacca gacctacccc
    19561 tctttgaaat ttctgacgag tggattgagg aaatgcggac tgagttgcca gagtttccaa
    19621 aagaacgtcg tgcgcgttat gtatctgacc ttggtttatc agactacgat gctagtcagt
    19681 tgactgctaa taaagtcact tctgacttct ttgaaaaagc tgttgcccta ggtggtgatg
    19741 ccaaacaagt ctctaactgg ctccaagggg aagtcgctca gttcttgaat gctgaaggta
    19801 aaacactgga acaaatcgaa ttgacaccag aaaacttggt tgaaatgatt accatcatcg
    19861 aagacggtac tatttcatct aagattgcca agaaagtctt tgtccatcta gctaaaaatg
    19921 gcggtggcgc gcgtgaatac gtggaaaaag caggtatggt tcaaatttca gatccagcta
    19981 tcttgatccc aatcatccac caagtctttg ccgataacga agctgctgtt gccgacttca
    20041 agtcaggcaa acgtaacgcc gacaaagcct ttacaggatt ccttatgaag gcaaccaaag
    20101 gccaagccaa cccacaagtt gcccttaaac tacttgcaca ggaattggcg aagttgaaag
    20161 aaaactagac agaacaaaac cagccctaag gttggttttt tcttctctac caactcccaa
    20221 taactatttt ggctttattt ccagagtatt ttatggtaaa atgaagagta ataatattta
    20281 ttaaagaggt aaaaacatga ttgaagcaag taaattaaaa gctggtatga cctttgaaac
    20341 agctgacggc aaattgattc gcgttttgga agctagtcac cacaaaccag gtaaaggaaa
    20401 cacgatcatg cgtatgaaat tgcgtgatgt ccgtactggt tctacatttg acacaagcta
    20461 ccgtccagag gaaaaatttg aacaagctat tatcgagact gtcccagctc aatacttgta
    20521 caaaatggat gacacagcat acttcatgaa tacagaaact tacgaccagt acgaaatccc
    20581 tgtagtcaat gttgaaaacg aattgcttta catccttgaa aactctgatg tgaaaatcca
    20641 attctacgga actgaagtga tcggtgtcac cgttcctact actgttgagt tgacagttgc
    20701 tgaaactcaa ccatctatca aaggtgctac tgttacaggt tctggtaaac cagcaacgat
    20761 ggaaactgga cttgtcgtaa acgttccaga cttcatcgaa gcaggacaaa aactcgttat
    20821 caacactgca gaaggaactt acgtttctcg tgcctaatct ctagaaagag gtcattctat
    20881 gggaattgaa gaacaacttg gcgaaatcgt tatcgcccca cgtgtacttg aaaaaatcat
    20941 tgctatcgct actgcaaagg tagagggtgt tcactctttt tcaaacagat cagtgtctga
    21001 taccctttca aaactttcac tcggccgtgg cgtttatctt aaaaacgtgg acgaagaact
    21061 cacagcagat atctatctct accttgagta cggagtaaaa gttcctaagg tagcggttgc
    21121 tatccagaaa gctgtcaaag atgccgtccg taatatggct gatgtagaac tcgctgctat
    21181 caatattcac gttgcaggta tcgtcccaga taaaacacca aaaccagaat tgaaagatct
    21241 atttgacgag gacttcctca atgactagtc cactattaga atctagacgc caactccgta
    21301 aatgcgcttt tcaagctctc atgagccttg agttcggtac ggatgtcgaa actgcttgtc
    21361 gtttcgccta tactcatgat cgtgaagata cggatgtaca acttccagcc tttttgatag
    21421 acctcgtttc tggtgttcaa gctaaaaagg aagaactaga taagcaaatc actcagcatc
    21481 taaaagcagg ttggaccatt gaacgcttaa cgctcgtgga gagaaacctc cttcgcttgg
    21541 gagtctttga aatcacttca tttgacactc ctcagctggt tgctgttaat gaagctatcg
    21601 agcttgcaaa ggacttctcc gatcaaaaat ctgcccgttt tatcaatgga ctgctcagcc
    21661 agtttgtaac agaagaacaa taaaaagaaa aagtgtttga tagatatcaa acactttttc
    21721 tttgcctccc actatctaaa aaaatgataa tagatataat tgtaaacaaa aatccagata
    21781 ggttttgcat gattgagaaa gttaaaaaaa actatggcag agaatcgtta atctcagatt
    21841 gtcggtaaaa cgataaacaa gggcaaaaaa gaaaccaatc agactataat ataataaact
    21901 aattggatct ctgtgagata gtatcaaatg actaagccca aagataaggc ctgataagat
    21961 gacatctaaa taatacttgg actagggaaa gaaggtattc ataaaatacc ctctatcaag
    22021 agtctcctca aaaacaggac cgatgattac aggcaggaca aaagataaga tagtcgataa
    22081 aaaggttggt tgtccatttg aaagaaccac ggtaaaatac tcatcatgaa tattcctatg
    22141 attaatcaaa tgagcatagc gtgcccaaaa attaccgaga atctgataaa ccacataagt
    22201 tgcaaataag gagaagacaa atgaccagtt ccagctcttt ttctttttta acctccaaat
    22261 taatagaagg aaacttccca ctaataccat tgttaaaata agagaataga catcagctcc
    22321 taaccctaaa atgatcgtca catacaattc aattgtttgt ggtaaatagg tagatagtaa
    22381 aataataagc aaaaatattc caaattgtct tagtttcttt gtgtttctca tcgtactttt
    22441 ttgaaagatt accctgttcg gaagccgtac ttccaagcat ctatataaga attaagtgcc
    22501 cttgcctcat atagggagca aattctctat aatataacca tctactatat ccatcttccc
    22561 aaacagcaag accacctgaa gtttgctcca agtcctcagt tgaaataact gtaaatgttt
    22621 ctgtacctgt cattgcaagt accttcttaa aatagattgt tgtaggctca catttatagt
    22681 atatttcttt tttgtctatt ttatagccca tctcctcaac tatcaatttt tcaacctgaa
    22741 ttgcattttt ccataaaaaa tgagaccttt ctagtctcat ttagtcattc ttagtatttt
    22801 ctaaatcgtt gatagcgttc ttccagcaac tcttctagcg atttttgtga aagtctagcc
    22861 agctccgttt ggagttcttt tttgacactc ttaatcagtt ctttactaga aagtcctact
    22921 tcagaaatca ccttatccac cacgtccatt tctaacagtt catgcgaagt gattttcatc
    22981 agttctgctg cttccatggc gcgagtaccg tccttccata aaatggaagc aaagccttct
    23041 ggactgagaa tggcatagat agaattttcc agcatccaga cacggtccgc gacagctaga
    23101 gccagagccc cgcctgaacc accttcaccg ataataatgg cgataatagg aactttcagg
    23161 tcactcattt ccatgagatt gcgagcgata gcttcccctt gaccacgttc ttctgctccg
    23221 acaccaggat aagcacctgc tgtattaata aaggtcacaa ctggacggcc aaatttctca
    23281 gcctgtttca tcaaccgcag tgcctttcgg tagccttctg gatgtggttg gccaaaattc
    23341 cgtttgaggt tgtcttgcaa actcttgcct ttttggatac caaccactgt tacagcttgg
    23401 tctccaagcc aaccaatacc accaacaact gcaccatcat cacgaaaaga acggtcacca
    23461 tgtaattgga taaattcatc aaaaatgcct gtcgcaaagt ccaaggttgt caagcgactc
    23521 tgctcacgcg cttctctgac tatttttgca atattcatct aggactccct ccatgcaatc
    23581 tgactaggct agcaatcgta tctggtaagt ctcttctttt gacaatagca tccacaaagc
    23641 catgttctaa taggaattct gccttttgga aatcctcagg caagctttca cgaaccgtat
    23701 tttcaatcac acgacgccca gcaaaaccaa ccaagctctg tggttcagcc agaatgatat
    23761 cgccttccat agcgaaagaa gctgtcacac caccagtcgt tggatctgtc aaaatggtca
    23821 ggtaaaagag accagcattt gaatgacgtt taaccgccgc agagatctta gccatctgca
    23881 tgagactcat gattccttcc tgcatacggg ctccaccaga ggctgtgaat aggacaactg
    23941 gcaatttttc gacagtcgca tactcaaaca aacgagtgat tttttcacct acaaccgtac
    24001 ccatagaagc catgataaag ttagaatcca taatcccaag agccacagtc tgacctttaa
    24061 taagagcagt tcctgtcaca acggcttcat gcagacctgt tttttcacgc atagatgcca
    24121 gtttcttttg gtaaccaggg aaatgcaagg gatccttgct ttcaatccct gtaaacaatt
    24181 ctttgaaggt tcccatatca atcgtcaaag ccaagcgttc ttgggcagaa atacgaaagg
    24241 tatagctaca gtgcggacag atacgttcac ttcccagatc cttctgatag atggtatgct
    24301 tacagcctgg acactgggaa aataattcat ctggaacctc tggcttagct tgaggttttt
    24361 ccctaaccga acgattggga ttgattcgaa tatacttatc ttttttacta aatagagcca
    24421 ttgattcccc ttttcggttt aaactcttaa agtcatttta ttctttttct tgatatttag
    24481 gtaagaaggt ttccatcaag aaggaagtat cataatcccc agcaatgaca ttgcgatctg
    24541 aaatgaggtc aagctggaaa tctgcattgg tctgcactcc ttcaatctct aattcataga
    24601 gggcacgttg cattttcatc aaggcgtcaa aacgattttc gccgtgtact atgattttgg
    24661 caatcatact atcataataa ggcggaatgg tataacctgg ataaactgct gaatccacgc
    24721 gcaagccaac tccaccactt ggcagataga ggttagtaat cttacctgga cttggagcaa
    24781 agttaaaggc tgggttttct gcattgatac gacactcgat ggcatgaccg cgtaggacaa
    24841 tatcttcttg cttaacagac aaaggctgac ctgccgcaat gcaaatctgt tccttaacga
    24901 tatcaacacc tgaaacaaac tctgttactg gatgttctac ctgaacacga gtattcatct
    24961 ccatgaaata gaaattgcta cttgcttcat caagaagaaa ttcaatggtt cctgcattct
    25021 catagccaac aaactctgcc gctcgaacag cagcagcacc tatttcatga cgcagcgttt
    25081 ttccgattgc aatcgaggga ctttcttcca aaaccttttg gttattcctt tgaagagaac
    25141 aatcccgttc acccaagtga atcacatgtc catgctcatc acctaggatt tgaacctcaa
    25201 tgtgccgagc tggatagata acccgttcta tgtacatggc accattgcca taattggcct
    25261 tggcctcact agaggcagtt tcaaaggcag aaacgaggtc atctggtttt tcaaccttac
    25321 gaatcccttt accacctcca cctgctgaag ccttgagcat aacaggatag ccaatttttt
    25381 cagcaacaat caaagcttct tcagagttat gcacttctcc atctgaacct ggtataacag
    25441 gcacacctgc tttaatcatc tgagcacgcg cattgatctt atcccccatc atatccataa
    25501 catgaccaga tggaccgata aacttgatac ctacttcttc acacatggtc gcaaatttgg
    25561 aattttcact gagaaatcca aaaccagggt gaatagcttc tgcctcagtc aagactgcag
    25621 ctgatagaac tgcattaata ttgagataag actctgttgc cttgccagga ccaatacaaa
    25681 ctgcttcatc tgccaacagc gtatgaagag cttccttatc agcagttgaa taaaccgcta
    25741 ccgtcgcaat ccccaattca cgtgccgcac ggataatacg aaccgcaatt tcaccacgat
    25801 tggcaattaa aatttttcga aacatggaga acctccttag ttcccaattg caaaagtaag
    25861 ggtaccactg gctgcaagct tgccatccac ttcagccttt gcttcaacca cagctatggt
    25921 gccacgacgt tttacaaaag tcgctgtcat aaccaattgg tcgcctggta caacttgctt
    25981 cttgaactta accttgtcca taccagcgta aaagaccagt tttcctttat tttcaggttt
    26041 tgataactcc aacacaccag cagtttgcgc caaggcttcc ataatcagaa cacctggcat
    26101 aactgggtat tgaggaaagt ggccgttaaa gaaaggttcg ttaatggtca catttttgat
    26161 agcaacaatg gtatcctcgc tcacttccaa gacacggtcc actagaagca taggataacg
    26221 gtggggaaga gcttctttga ttccttgaat atcgatcatt tgatacgtac caatccttta
    26281 ccaaactcaa ccatttcttc gttagagacg agaatttccg ttaccacacc atccttagga
    26341 gctgggattt cattcatgac tttcatggct tcgataatta ccaatgtttg accttttttg
    26401 acactatcac caactgtaac aaaggcaggt ttatctggtc cagcagccaa gtaaaccact
    26461 ccaacaagtg gactctctac aagatttccc tcagtagcca cacttgcttc agctggagct
    26521 ggaacttctt ctgctacagt ctctgctgga gcagatgtag gagctactgg actcggtgtt
    26581 gctagaacgg gtgctggagc gacttgagtt gcaacttcag gcacaggtct tgcttcattc
    26641 ttgctaaact gcaactcatc cgtcccattt ttataagaaa attctctcaa acttgactgg
    26701 tcaaattgag tcatcaagtc tttaatatcg tttaaattca tacttatcta ttctcccaac
    26761 gtttgaaagc aagaactgca ttgtggcctc caaaaccaaa agtatttgaa atagcgtatg
    26821 gaatttcttt ctccaagcct tgtccataaa cgacattagc ttcgatataa tctgatactt
    26881 cacttgtccc agctgtcatt ggtacaaagt tatggcgcat agcttcgatg gtgacgatag
    26941 cttctactgc acccgcagcc cccagcaaat gtcctgtaaa agacttggtt gatgatacag
    27001 gtacttcctt accaagaaca gctacgatag ctccactttc tcctttttca ttggcaggag
    27061 ttgacgttcc gtgagcattg acataggcta cttgctctgg agaaatctca gcttcttcca
    27121 aggctagttt gatggccttg atagctccct gaccttctgg atgtggagaa gtcatgtggt
    27181 aggcatcaca agtatttccg taaccaacca cttcagccag gatagtagct ccacgttttt
    27241 cagcgtgttc aagactttct aaaaccaaca tccctgaacc ttcacccata acaaacccat
    27301 tgcgatcctt atcaaatggg atcgaagcac gagttggatc ctctgtagta gagagagctg
    27361 ttaaggcttg gaaaccagcg atggcaaaag gtgtgataga agcttctgtt cctcccacca
    27421 acatcacatc ttggaaacca aacttaatgg agcggaaggc atccccaatc gcatcatttg
    27481 atgaagagca ggcagtattg atagatttac aaacaccgtt tgcaccaaaa cgcatggcta
    27541 cattcccaga agccatattt ggtaaagctt ttggaagagt cattggtttg acacgtttgg
    27601 gtcctttttc atgaaggcga agtacctgat cttcaatttc cttgattcca ccaataccag
    27661 atgcaacgat aacaccaaaa cgatccctat taagagcctc tacatcaaga ttggcatgat
    27721 ttacagcctc ttgggctgca tacaaggcat ataaagaata gttatcaaaa cggttggtat
    27781 ctttttttac aaagtattta tcgaacggaa aatcttggat ttctgccgca ttatgcacat
    27841 caaagtcact atgatcaaat tttgtaatgc caccaatgcc gattttccca gttgctaaac
    27901 tattccaaaa ttcttctggt gtatttccga ttggagatgt tactccataa cctgttacca
    27961 ctactcgatt tagtttcatt cttttcacct ctagctttcg ctacatactt aagccaccat
    28021 caatggcaat cacttgacca gttagataat cttggcctgc taaaaatact gtcaaatctg
    28081 caacctgctc tgcctgccca aattctttca tcggaatctg agctagtgta gcttccttaa
    28141 tcttatctga taagatagca gtcatatcag actcaatcat tcctggagca atcacattga
    28201 ctcgtatatt ccgactagcg acctcgcgtg ccacagactt ggtaaagcca atcaagccag
    28261 ccttagaagc agcatagtta gcttgaccaa tattccccat caaaccaaca acactagaca
    28321 tattaatgat agcaccttct ctggctttca tcatcggttt caagactgat tgtgtcatat
    28381 taaaggtacc agtcagattg accttgagca ctttttcaaa atctgcttct gtcatcttga
    28441 gcataagagt atcttgggta atccctgcat tgttgaccaa aacatctact gaacccagtt
    28501 ctgcaatagc ttgatcaatc atacgcttag cgtctgcaaa atctgataca tctcctgaaa
    28561 tgggaaccac cttgatacca tagtttgaaa actcagcgag caattcttct gagattgccc
    28621 cacgactgtt taagacaatg ttggctcctg cttgagcaaa cttgtgggcg atggcaagac
    28681 caattccacg actcgaacct gtaataaaga tatttttatg ttctagtttc atttttttcc
    28741 tttcaaaact tctacttatt ttagtctatt tttctaaaag tgctactaaa ctcgcttgat
    28801 cttccacatg agctaagtga gcagtttgat caattttttt aacaaaacct gacaagactt
    28861 tccccggtcc aatctcgata aagttgctta tgcctgcttc ttgcatgacc ccaatacttt
    28921 catagaaacg aacgggttcc ttgacctgac gcgtcaagag ctgagcaatg tcctcttttt
    28981 gcatcacagc agcttctgta ttgccgacta ggggacaagt aaaatctgaa aaacttacct
    29041 gagctagagt ttcagctagt ttctggctag ctggctcaag gagagcggtg tgaaagggac
    29101 ctgacacctt aagaggaatc aagcgtttgg cacctgcttc ttgcaaaagt tcaaccgctc
    29161 gatcaactgc aaccacttct ccagcaatga cgatttgtgc aggtgtgtta tagttggctg
    29221 gagtaaccac tccaagttca gaagcttttt gacaggcttc ttcaatgacc tctactggcg
    29281 tattgagaac tgctaccatc ttgccagagt cagcaggagt cgcttcttcc atataggctc
    29341 cacgcttagc taccaaggca accgcatctt caaaatccaa ggcgccgctt gccaccaagg
    29401 cagagtattc tccaagagac aaaccagcaa ccatatcagg ctgatagccc ttttcttgca
    29461 ataaacggta gatagcaacc gaagtcgcta gaatggctgg ttgcgtatag cgggtctgat
    29521 tgagtttgtc ctcttccgta tcgatgagat aacgcaaatc ataaccgagc acctgactcg
    29581 ctcgatcaat cgtttcttta acaatcggat actgatcata gaaatcccgt cccatcccta
    29641 gatactgggc accttgacca gcaaataaaa aggctgtttt agtcatttct tacaactcct
    29701 gtccagcgag aggcttcttc ttgaattttc ttagcggctc cgtaatacaa atcttttagg
    29761 atttcttcag ctgtttcttc tttagaaaca agccctgcga tttgacctgc catgacagag
    29821 ccaccctcca catcaccgtg aacaactgct ttggctaggg cacctgctcc catttgttca
    29881 aagatttcta aatcaggatc ttcctgctta aaggcatctt tttcagccag ttcaaaatct
    29941 ctagtcaact gatttttaat agcacgaaca gcatgaccaa agtgctgagc tgaaatcgta
    30001 gtgtcaatat cccttgcttt taaaattttc tccttgtagt ttggatgggc attcgactct
    30061 tttgcaacta caaaccgtgt ccccacctgt acagcctctg cacctagcat aaagccagcc
    30121 gcagcacctt caccatccgc aattcctcct gcagcaataa caggaataga tacagctgtg
    30181 gctacctgtc gcaccaaggt catggttgtt aatttaccga tatgcccccc agcttccatt
    30241 ccttctgcaa taacagcgtc tgcaccgatt ttttccatgc gtttagctaa agcgacacta
    30301 ggaacgacag gaataacgat tatcccagct tcatggaaac gttccatata cttgcttgga
    30361 tttcctgctc ctgttgtgac aactttaaca ccttcttcaa taacgagatc cacgatatct
    30421 tccacaaagg gagataagag catgatgttg accccaaagg gtttatcagt caatgatttg
    30481 attttatcaa tattggcctt gacaacttct ttcggggcat ttcccccacc gataattcct
    30541 aatcctccag ccttggaaac agcccctgcc aaatcaccat cagcaaccca ggccatccct
    30601 ccttggaaaa taggatagtc aatcttcaat aattctgtaa tacgcgtttt catagtgcct
    30661 ccaaccttcc ttgcttacgt aatagttcga tttcaccata atttgacagt caaactatta
    30721 cctaaacaag agggagtggg tttctcccta ctccttctac taatattctg cttattttgc
    30781 ttgctcttca acgtaagcaa ccaagtcacc aactgttttc aagtcatttt ctgcttcgat
    30841 ttggatatca aaagcatctt cgatttctga gattacttgg aacaagtcca atgaatctgc
    30901 gtccaaatca tcaaaagttg attcaagtgt tacttctgat gcgtcttttc caagttcttc
    30961 aacgataatt tcttgtactt tttcaaatac tgccatgata ggactccttt aaaataaata
    31021 gtttttttta taacaatgtg ttcaccacat gattacctaa attgtaagaa tgagcgtgcc
    31081 ccaggtcaag cctccaccga agcctgatag aagaacagtc tggctaccat ctaaagggat
    31141 gagaccttgt tctacacact ctgaaagtaa aatcgggata ctggctgcac tggtattgcc
    31201 atattccatc atattggctg gaagtttggc tcggtcaaca ccaatttttc tagccatctt
    31261 atccaaaata cggtcattgg cttgatgaag tagcagataa tccaagtctg tcacctctat
    31321 aggagattca tcaatagtct gcttgataga cttggctaca tctcgaatgg caaaatcaaa
    31381 gactgtgcgt ccatccatct tcaaaaacga atctgcactt tcttgatctg aaaatggaga
    31441 atgcaaacct gaatgcccat aagttaaaca ctcgctgcga cttccatcgc tattgagact
    31501 ctcagctaag aaatgctctt gctcgctagc ttctaacaag acaccaccag caccatctcc
    31561 aaacaacaca gctgttgatc gatccgacca atcgactgcc ttagagaggg tttcactacc
    31621 aatcaccaag cctttttgaa agcgaccaga agcgataaac ttttcagcag ttgaaagagc
    31681 aaatacaaat ccactgcaag ccgcggttaa gtcaaaagca aaggctttat tagcaccaat
    31741 attagcttga acacgagcag ctgtagaggg catcatcgaa tctggagtaa tggtagctag
    31801 gatgataaaa tccagttctt ctcctgttat tccagctttt gccatcagtt tcttagcaac
    31861 ctctgtagcc aaatcactgg tagattctgt tcttgaaata tgcctttgtc gtattcccgt
    31921 tcgacttgaa atccactcat cattggtatc cataatctga gccaagtcgt gatttgtaac
    31981 cacttgctct ggcacataat gagcaacctg acttattttt gcaaaagcca ttatttcaaa
    32041 tcctccaaaa attggtaaag attagtcaaa cctttaccca tgacagcaat ttcttcctcg
    32101 ctcatgccat caataatttt ttctaccatg gccttgtgga agcgtttatg cagcctatga
    32161 atcaagcgac ccttctttgt caaatgcaga tgcaccacac gacgatcctg ttctgaccga
    32221 actcgctcaa tgtagccctt acgctctaaa ttgttcaaac ttgtcgtaac agttccaaga
    32281 gttaccatca actcttttga cacttgactt ggagtcacgt ctggagcctt accgatgaca
    32341 tcaatcgtat gcatttcttt gatggagata tccttaaaac gactacctct caagttcact
    32401 tcctcaatta caaggacatt gttaaatata gatgttaaat attcattgat tcgttggtag
    32461 tccatttttc atatccctcc ttcttcaaaa aacttttaca atcaaaacat ttgacagaaa
    32521 gaattatatc aaaattcaaa gaatgatgca agtatttttt attttcctgt aaatttaggt
    32581 cttcttctct ccgaatgagc tcgcactcct tctttgaaat cctctgtttg agctaaggat
    32641 ttctgtaggt tcagttctaa agtagcgtaa ccctgccagt ctttaaactg gctctcccaa
    32701 accaacttct taatggcagc ataggaatta cttgaagcac gtcttaattt tttaagaagc
    32761 tgttctctcg tcttttcaag tttttcagct tcagaaacgc ggtaaaccaa cccccattct
    32821 agggcttttt ctgccgttaa agcctctcct gtcatagcta attgagcagc acgcgtcaca
    32881 ccgatactgc ggctcaagag atgaattccc cctgcatctg gagccaaacc aacaccaaca
    32941 aaggcttgga taaacttagc cttatccgtc gccaaacaga aatctgccgc aacagccata
    33001 ttcgctgcgg cacctgcaac agcaccgtca acttccatta aaacaggttt ggctatttgc
    33061 ttgattttat aagaaatcgt attgaccaac tctgcgattt ttgtcaatga tggaatatca
    33121 tcctcatcca ctgcccgctt catctctacc aaatctcccc caactgagaa gacctttcca
    33181 ttggcattga ttaagataaa atgcacagct ggattttctt ctgccaaagt cagagcttct
    33241 aaaatctcct cacacatggg aatatgaaaa ccatttgcga cctcaggacg gttcaaggta
    33301 aggattgcca agtcctcttc aagctgataa ataatgtgtt ccatcagggc tcctttttat
    33361 tttataagca gtttatactc ttcgaaaatc tctttaaacc gcgtcagctt ccatctgcaa
    33421 cctcaaaaca gtattttgag ctgacttcgt ctagcttctt agtttgctct ttgattttca
    33481 ttgagtgtta aattatttca ctgtcaaagt atatcttttt taggagcaga aagcaagaaa
    33541 aaatcgactg aaagtgtctc agccgataag aaaggctcgc tttaggctag aaagcatctt
    33601 attttcttca ttgaaaaaag cctttctttc tgctataatc gtataaaata cttactttag
    33661 gagttcttat gaaagttgtt aaatttggag gtagttctct tgcctctgct agtcaattag
    33721 aaaaagtttt aaacatcgtc aaaagcgatt cagagcgtcg ttttgtagtc gtttctgcgc
    33781 ctggtaaacg caatgctgaa gatactaagg ttacggatgc cctgattaaa tactaccgcg
    33841 actatgttgc gggtaacgat attagcaaga gccaaagctg gattatcgac cgctatgctg
    33901 ctatggttag tgaattggga ctaaaaccag ctgtgctaga aaaaatttct aaaagcattc
    33961 acgccttggc cactcttcct attgaagaaa atgaatttct ctacgatact ttcctagcag
    34021 ccggtgaaaa taacaatgcc aaattgactg ctgcctactt taaccaaaat ggtatcgatg
    34081 cacgctatat gcaccctaga gaagctggga ttgtggtcac aagtgaacct ggtcacgctc
    34141 gcatcattcc atcaagttat gacaagattg aagaattgac aaacaccaat gaagtccttg
    34201 tcattcctgg tttctttggt gtcactaagg aaaatcaaat ctgtactttc tcacgtggag
    34261 gttctgatat tacaggttct atcattgctg ctggtgtcaa agccgacctc tatgaaaact
    34321 ttacggacgt tgatggtatc tttgcagccc accctggtat tatccaccaa ccacactcga
    34381 ttcctgagtt gacctaccgt gaaatgcgcg agttggccta tgcaggcttc tcagtccttc
    34441 atgacgaggc tcttcttcct gcctaccgtg gaaaaattcc tctggttatc aagaatacca
    34501 acaaccctga ccatccaggt actcgtatcg ttctaaaaca cagtaatgat gaatttccag
    34561 ttgtgggaat tgctggtgac tcaggctttg tcagcattaa catgtcgaaa tacctcatga
    34621 accgtgaggt tggatttggc cgcaaggttc tgcaaatcct ggaagaactt aacatcggtt
    34681 gggaacatat gccaacaggt atcgacgatc tttctatcat tctccgttct cgccaactaa
    34741 ctcccatcaa ggaagaagaa atcctgcgtc agttggttca aaaggctaaa gtagatcatg
    34801 cagaaatcga acacgacctt tctatcatta tgattgttgg tgaaaaaatg aagagccaca
    34861 tcggagtgac tgctactgcg acacgcgctc tatctgaaaa caaaatcaac atccagatga
    34921 tgtctcaagg ttctagtgaa gtttctatta tgtttgttgt caataaagac caagagaaag
    34981 cagcaattaa agccctctac aatgcctttt ttggagaaag taaggaagac taagcatggc
    35041 ccaatcactt aacaaaacag tactcctcag tacgacaggc acttcctacc tctctatcgc
    35101 tgggaaagtt gggaaattcc ttgtcggaga tcaggctttg gaattttacc cagatgtcaa
    35161 tgtcgaacaa tttatccaga ttccttggag ccatatcaat cagattggag ccaatgtcac
    35221 tggacgcaaa atcagccgcc acttcgaagt ctttacagac aaaggaaaat tcctctttgc
    35281 ttcaaaagac tcaggtgcca ttctcaaaat tgcacgcgaa aaactaggca atgacaaggt
    35341 cgtcaaactt ccgaccctga ttcagacaat tagccaaaaa tttaaaaatc tatttgcaaa
    35401 aaagtagaaa ctttagtata atcatagcaa cggataagta ggttatcttc ttctttcaga
    35461 aagtctgcgg gtactgcgag cagataggag ggataggtga aattctaccg ttagtaacaa
    35521 ttacatacac aatcaagtgc acacctgtga agttggatgg aaccgtggcc ctgccactcc
    35581 aacgttttgt caggcgtgct tttttcataa aggagttctt atgttagata tcaaacgtat
    35641 tcgtacagat tttgaagctg tcgcagaaaa attagctaca cgtggtgtag atgctgctgt
    35701 cttgaatgaa atgaaagaaa tcgatgctaa acgtcgtaac atcttggtca aggttgaaac
    35761 tctcaaagca gaacgtaaca cagtttctgc tgagattgcc caagctaagc gcaacaagga
    35821 aaatacagat gacaagattg ctgccatgca aaatctatct gctgaggtta aagccttgga
    35881 tgctgaattg gcagaaatcg atgctaaatt gacagaattt acaacgactc ttccaaatat
    35941 cccagctgac agcgttcctg ttggggctga cgaagacgac aatgtggaag ttcgccgttg
    36001 gggtactcca cgcgagtttg acttcgaacc taaagctcac tgggatctcg gtgaagacct
    36061 tggtattctt gactgggaac gcggtggtaa ggtaacaggc gctcgcttcc tcttctataa
    36121 aggcctcggt gctcgtttgg aacgtgctat ctacaacttt atgttggatg aacatggaaa
    36181 agaaggctat actgaagtca tcacacctta catagtcaac catgattcta tgtttggtac
    36241 tggtcagtat ccaaaattta aggaagatac ttttgaactc agcgatacca actttgtctt
    36301 gattccaact gctgaagttc ctctgacaaa ctactaccgt gatgaaatct tagacggcaa
    36361 agatcttcca atctacttca ctgccatgag tccgtcattc cgttctgagg ctggttctgc
    36421 cggtcgtgat acgcgtggct tgatccgttt gcaccaattc cacaaggttg aaatggtcaa
    36481 atttgccaaa ccagaagaat cttacgaaga attggaaaaa atgacagcca acgctgaaaa
    36541 cattcttcaa aaactcaacc ttccataccg tgtcgttgct ctctctactg gagatatggg
    36601 cttctcagct gcgaagactt acgacttgga agtgtggatt ccagcacaaa acaattaccg
    36661 tgaaatctca agctgttcaa acacagaaga tttccaagcc cgtcgtgccc aaatccgtta
    36721 ccgtgatgaa gcagatggca aggtgaaact ccttcatacc ttgaacggtt ctggacttgc
    36781 agttggacgt acagtggctg caattcttga aaattaccaa aatgaagatg gttctgtgac
    36841 catcccagaa gcacttcgtc catacatggg tggagctgaa gtcatcaaac cataaaaaat
    36901 aaggtttagc tatttctagc tagacctttt ttcgtaacca aatcagataa gcacctagta
    36961 caaagaataa aatagttagg catataatgg tttcagccaa taccaggtaa tccagaaatg
    37021 gaagtttcaa aattccctga gccatcttga gcgaggtcgc tgtgataatg gttgggaagg
    37081 tgagggctga gaaggctggt tgaaaacctt gttttaaaat gttgggcaga cgagttaaaa
    37141 caaagaaaaa gaaggattga gaagccaaaa tcatgacaat caagacccaa gtcggcaggc
    37201 tggttcctcc tactcgaact agagaagcca agagtagaga gaaaggagca cagtagattc
    37261 cttcttgtcc aagcaaggct aatgggagtg gatgtttctt taaatcgcta taaataaggg
    37321 gatagagata gaaggtcaag agaaaaccaa aactcagggt cgcataggcc atttcgataa
    37381 tacctaccag aggataggtc aaggcagcca ctgctatccc cacatagaga accgtccaac
    37441 ttggagtggc atgaaccctc cgccctggac aagcaaactt gatggtaaaa ccagcaatca
    37501 aggtcaaatc caagagaaat gaaaaccacc aaatcccttg tgctaccaaa ggaagataag
    37561 agaatacgcg aaagacatag gtcgataaaa tcatcccagc cataggaaag gttgccattc
    37621 ctgacaaaag agggggcttg gtcaattctt gcttggtttc tttccaatta aagagatgca
    37681 gaattagaaa gtaaatccat aaaaccaaac cagtcagact aaaaagatgg gatagaactg
    37741 gcaacgtatc taaaataaga tttccagctc ctgccaaacc tagcaaacaa cctgaaaata
    37801 ctaaggggag ttttttcatc ctaacctcca ataatcatgt tagtttcagt ataacataaa
    37861 agcgcttaaa tgaggattta aaaaaacgaa gtccgattat ttcagacttc attttactca
    37921 gatatgaatt aggcataagg ttgcaattct ggattaattg gtgtattagc taagttgttg
    37981 gcatagttac agaggattgc taggctgaca ccaaaaacca catccaaggc attttgttga
    38041 gtgtagccag cttctaaaaa ctcagacaag gcttcatctc ctacacgacc cttggtattg
    38101 ataactgcca aggtaaactt agctagggta tccaatttag gatctgtttc aattggagta
    38161 cgattgcgaa gagcttgaat caagtcatca ttcatctgga tttgtttgat ggaaaaggct
    38221 gtgtgacctg cgacacagaa ggcacaacca ttggtcacgg ctgccgtgat ttgcaccact
    38281 tcacgctcaa cgggtgtcag gctgttgcga cggtggatag atgagacaat ttggtaggct
    38341 tctaaaacag tcggggcatt ggccaagaga ccgattaggt tgggaatata gccattgttg
    38401 tctttttcta ctgtttcaag aatttctttc acttctgctg gtgctgactc tactgtatgg
    38461 atagtaaatg ttgtcataag atacctcttt tcttattgtt gacactaata ttattggaaa
    38521 atcttataaa atcctgattc ctaagtttat ctaagataaa gctttattct ctcataagat
    38581 tttcgttgtt atattagttt atcacacttc caatcacttg cataatatat attatatatc
    38641 aggctgataa aaattattta taggcaaaaa aatcacacga gctgtgtgat tccattattt
    38701 gtcaaaatac tttttagttt cagcaataac gactggcgac aagaccaaga gggcaatcaa
    38761 gtttggcaga gccatcaagg cgttaacgat atctgcgata atccagacca tatccaactc
    38821 gataaatcct cctaacaaga ccatgagcac aaaaaccaca cggtagagcc agataaagcg
    38881 aaccccaaag aggaactcaa aacagcgttc tccgtaatag ttccaaccta gaatcgttgt
    38941 aaaggcaaaa agtacaagga agatggtcaa gagagcaggc ccaaagtgtg aaaagactgt
    39001 tgagaaagct gactgagtca aggcaacccc attcaagtca ccgctccaaa ctccagttac
    39061 caagatggtc aaaccagtta gagtacaaat gatgagggta tcaataaagg ttcctgtcat
    39121 ggaaatcaaa ccttgctcta ctggttcatt tgtcttggca gctgcagctg caataggagc
    39181 agaacccaga cccgattcgt ttgagaacac accacgcgcc acaccatttt gaatagccat
    39241 ccgaacgcta gcaccagcaa atccacctac cgcagcaagg ggactaaaag ctgaggtaaa
    39301 gactaaagcg attgtgccag ggatttttcc gatattaaag aaaataactg taagagttcc
    39361 taagatataa atgagggcca taaaaggaac aacagtagtt gaaaccttag aaatagactt
    39421 gagtccacca aagactgcaa tcgctacaaa gacagacaag acgagagctg tgatggctgg
    39481 cgaaatcgtc gttgtatttt ggatagattc tgcaatcgag ttgacttggg tgaaggttcc
    39541 gattcccaag agaacaacca atactcctgc tactgcaaac aaaacagcaa gtggtcgcca
    39601 cttttctccc atccctagaa ggatatagtg catgggacct cccgctactg caccatggtc
    39661 gtccttggtg cggtatttga tggccaagag tccttccgca tacttggtag ccattccaaa
    39721 gaaagccgcc atccacatcc aaaatagagc tcctggtcca ccaaccttga tagccgtcgc
    39781 aactcctatg atatttcctg ttccaacagt tgatgccaag gctgtacaca gagctgcaaa
    39841 actggataca tcaccatgtc ccttatcctg gataaaaata agctgaaagg ccttgggcag
    39901 acgcaaaacc tgcaagagtc ctagccgcat ggttaggtaa atccctgttc cgaccaataa
    39961 aatcaagagg ggcggtcccc aagcaaaagc atcgattgat ttaagcaatt ctaacatttc
    40021 cttctcctat cgtttcaacc ccaaaagaaa gagcacatgc aagatacatg tactctggaa
    40081 tgcttagata aatgctaaaa agcggtctat cctagctctg tccttttacc tgagagtttg
    40141 agcagttgcc tgccttgccc cttcggtgcc tttacggtct ctccagagtt ccgtccattt
    40201 acagtcatgg aaaatcaaac gattccccac ttctattaaa cttcattcgg tgttggtatt
    40261 taattgattc ttattttaca aaaaatgttg gcttttgtca atgtgttttg gaaaaatctt
    40321 atttgactct gtagaagaag gattgagcat tcccatgtgc gtggggtgct attagttatt
    40381 aaatcaagct gtttcactct tattccacac gatataagaa ttgtcttgga tcaccatgta
    40441 gcggaaatgc agcatggaag atgattcgat ctttactaat atccgaagca tccgtgacca
    40501 actcacccct agatgtccca tccggtattc taacacctgc tggtacgaac tgaataaaga
    40561 ttccaaagtc tggtgctgaa taacgagctc gtaaaaaacc atttacaaat tctgattctg
    40621 taaggtcaac tttaaatttc tctggtgcta tcaagccatc tttactaaag actaagtctt
    40681 ctcctccatg accattactc catcttccct caatactaga aaaatctcca tttttgatgg
    40741 cgtttatatc cattttccct gaagctgttt tgctagttga agatgctgtt gcagcaaatt
    40801 tttctgttac agatttccag gtcagactag atagattcat tcgagtacct ggactgactt
    40861 catcctctgt cttagcttct ttaaccttct ctagtttgtc cccactacta ttcaatttcc
    40921 aaatggtatg aatggtctgt ggatctcctg cgaacggatt ccactgggta tagagattac
    40981 cattttctaa tagataggcc ttgaaacgag ttccaagcat ctgcatttta ttttcagcat
    41041 tggtgaggcg aataactttc tgatctttga gtgtaaaaat atctaaaatc tcactaccat
    41101 ttttcgaaga gacaatcaat tcatcaatgc catttttgtc catatcaacc attgcatagg
    41161 taaaggcttg actgcgttct gccattcctg catagatatt agcagttgga ttgatgttat
    41221 ccttaacctc tgacttatag tctaaaataa attcataatc cttcaaaatg ctattataag
    41281 gactgtaatc tacacttggt ttccccttat ctgcactgct tcctcctgga agtttatctg
    41341 aaactgactt ccagcttaag gtctctagag aaatgggcga accgacccca agatctgcta
    41401 gttcttgagc ttccttatcc tttaccaaag actgcccatc ttcactaaat tggtagtgag
    41461 catagatgtg actcgttgct gtaccagctc cacgatagag cagagaattg tctggaagga
    41521 taccgaccgt cattctctca ccaatctggt ctaaacgatt ttcttgattg gtcaaacgaa
    41581 tcaccttttc gtctttcagc gtacgaatat caagtaaact cttttcgcca ctcttcattt
    41641 caagagcaag taaaagttca tcgactccat cattattcaa atccgtcttg tggtaaacca
    41701 catctgtata aaagccttga gaagacttca cttgactagc cagaggattg acatccatac
    41761 ctgtcggcaa ggtgcctttc gctacttttt catagtcatc caaaacttta ttataggaac
    41821 tgtagtctat ctctggagtc gctacagatg tttctgatgt tgaatcagat ggtgtttctg
    41881 cgcttttgtt ccaaggtaaa tactgacagc ctcctagaac tagtgtcagt aaaagtgttg
    41941 tggctaataa aaactttttc atattactcc tttatctaag agaaaggaac cagcctgtgc
    42001 caattccttt cgctattttt attgtatcaa aatgttgcct ataaacaaat tattttccgt
    42061 ttctatttat ttgttataag ccatttctca caagctatca ttctagcgaa cccacttacc
    42121 tgagccgtct actttgtagc catctggggt acgttcgttg actgccatct taccatctga
    42181 tttgaggtag tagtcaccta cccatgtatt acgggcgtaa cttccttctg atgttaggta
    42241 atagtaagat tggtagctac tatcatagat ccactcactc ttagccattt taccatctga
    42301 tttgaggtag tagcttccag accaagcatt acgtgcatag ctaccctctg ctgtcaagta
    42361 atagtatgat tgatagttat tgtcataaat ccattcgctc ttagccatgt agccacctga
    42421 cttgaggtag taacttccag accaagcatt ttgaacaaag ttacctgaag cattgaggta
    42481 gaagtatgaa ttgtactgaa catcaaaaat ccattgattg actactttca caccagcttt
    42541 gtagtaagaa gaacctgacc agccagtctg acctgagcta gagttagtag ctggttttga
    42601 agtttcagta gctgttggtt tttccgtttc tttaggagtt gaagagtcta gaggattgac
    42661 atatttttga tctttaacag tgaatgtcgc tgatttgcca ataaatttat acaaaacact
    42721 tctgtaatcg tcttctccat gaaattgtaa gtaatattca ccgtctggaa catttgcaaa
    42781 attagtccaa ccttgctttg taatcggaac agatgatcta tcgaaccttt cattgaaagt
    42841 atcttttcta ggaatttgcc ctgtttttgc atttacaata tctgcatata tatatacatg
    42901 atagtgtaca ggtacatttt caacagtcat atccacatag atacttccat tttctgatcc
    42961 tggtgtaatc ttagatttta cctcatgatt ctcggtacga gtaatttccg catgcactgt
    43021 ttgtgctgaa aaagggagaa ctcctgctgt gtcgattgtt gatactactc cgactgttga
    43081 aagtgccaca gcacatacta ataatttctt tttgttcatg ttattcattt cctttatttt
    43141 atttttaata tttatttgtt taaaacctat cactcatcta tccgacaaaa cgatgattct
    43201 ttacacgaaa gacaactgat tggccatcgt ataccttgcc atcttgtcct tttcctttga
    43261 taacaaagcg ataactacca tctggagtgg cactaaagaa gtgacgagtt tgaaagacac
    43321 gtaagcttgg attgtaggtc acagtaaact gggtttgtgt agaaactgaa cctgtatttg
    43381 catcaactaa ggcaaaatca taggctactt gataagatga ggatggagtg ctaggtagag
    43441 cgatatcaat ataggtcata gcatcattga cattgtaaag gcttattcct aatgatgttg
    43501 cttgtgaact gcttgctgta tgagttccct cagaactaat ccacttgcct gatccatcca
    43561 cttggtagcc atctggtgta cgttcgctaa ctgccatctt tccatttgac ttgagataat
    43621 aatcacctac ccatgtatta cgagcataac ttccttccga tgttaagtaa tagtaagagc
    43681 tgtagttatt gtcataaatc cactcacctt tagccatctt tccatttgac ttgagataat
    43741 aatcacctac ccaagtatta cgggcgtaac ttccttccga cgttaggtag taatatgaac
    43801 tgtagttctt atcatagatc cactcgcttt tagccatctt accgtttgac ttgagataat
    43861 agttgcccac ccaagtattg cgagcatagt agccatctgg agttaagtaa taataagctc
    43921 catagttctt atcatagatc cactccttct tagccatgta gccacctgac ttaagatagt
    43981 aatcaccctc ccatgcattt tgaacataat tacctgaagc atctaggtag aagtaggaat
    44041 tatagttctt atcgaaaatc cacttactag tgactttagt accattttgg tagtaagatg
    44101 atcctgacca accagacgga actgtagatt gtggatttgg agttggatct ggggttggtt
    44161 ttttatccga ttgtgggatt ggagctggat ttggagttag ttttttatcc gtcagattct
    44221 taatcgcctc tttaaactct tctacagttc ccttccactc tatgtaattg gcaccagact
    44281 tattctcatt agcaatatag ttgcgagcag attcttggaa ataagataat tctggagtgg
    44341 tttttgtggc ccaaataatg ggacgattag cagtacctct ccaattttta aatacttctg
    44401 aatccttcgg aacaagaata taatattttg cagctgtagt cagcgtttgt gtgtcagctt
    44461 gtaccgtttt tgctgaaaaa ggtagagctc ctgctgtatc tacaagagac acaagaccaa
    44521 atgttacagc ggctaggctg gttactaaaa ctgtttttga cttcattatc aaaacctcct
    44581 ttaaattttt attatttagg cttacagtaa gggatggact ctactatatt tatgaaaaga
    44641 gtatctgtgt ttatacttta tttgattagc aaatgaaatt tttatgaaaa aagtatactt
    44701 aatctttttc ctagttatta gactaaagac tttctatttt atcatttcca cctacttgtc
    44761 aaatatgcct tttctcctat tgtccaattt tgatcataag gatccactga ccattttgtt
    44821 gctagcaaaa aaaacggaaa cttactataa ccaatttgag cttcgactag atcggtggtc
    44881 gtattgtacc ttctatctcg tttccactta ccaatttttt gacttctatt cctattccag
    44941 ataaaaagtt cctctggtag tgcataaatt ctaccgtcat gagaactccc tctcattaca
    45001 ggataaaggt actgatgcaa ctgatattca catcgcttat ttaagagcca atatcctaga
    45061 atcatataga agggatttat cttttcaaga ggtaagataa ttggcaaagg taaagcatta
    45121 ctcacatcca ctggttttgt aagatacatt atccataaca atactgatga aaaataaacc
    45181 ataaatgtat gtagtggtat tctattcaaa acaatcatat agaatttgta attctttatc
    45241 tttatcaaac agcgtcttac attaatactg cccacaatta ttttatatag aaaaatcaca
    45301 aagaagattg gtgaaatata tacaaaaact aaaaaagatg ttaaaacgat aaactcagct
    45361 attccaataa cagctggata ttgaacttta tatgtttcaa aatcctttaa tacaatgaac
    45421 catggagcga taaaatacaa gcacgagaat attagtaaag caatttttaa atagaaaata
    45481 ttcaagaatt gacttaattt taaaatgttt gttctcatat aacttcctgc tctcctatcc
    45541 atccaattta tcatttctta aaaccatgat aatcttcaag cagaattccc cctatatttg
    45601 tttaataatt tgtagataaa tattaatcta aacttattaa aataatttag aatacttact
    45661 tctacttcct tagaaatatt tttctggatt gtataagttc gagtaaattc aattcggctc
    45721 atattattct taaaatataa ctcatataaa aaatctacaa catcaattct ttactatttt
    45781 tacataattt aacgtttcaa aagtaaatta aatgtctgcc gaatcatctg cccaccaatt
    45841 gtatccctaa acttatcttc cctagataac tcatctaaca tctcttctag actaacagcc
    45901 ttaatatgac ctggccaaaa gacattatcc aatctacctg cacccttata ggtaggcatt
    45961 aagacaacac gtgtttccaa gcgataatat tttaataaac tcgcaaattt atgggaaaag
    46021 ctttcttctg cataagacat gttaggggac atttttttag gtctgcctat ttgagcacct
    46081 gtagcactat ctatagtgta caataaacca tccgcttctc tataaatcac atttcctgaa
    46141 gcataaaatt ttaaatctac taaccaaatt gtagatccag aaacaataac acaatcaata
    46201 tccgcatcta ccctttcatc ttctaaattg agattatgaa cagaccaaaa ggtaactagt
    46261 ttttctaaaa gccctttttt ttgtaatgct ttagcaaaat tgatttcacc ctcttgacca
    46321 agattaacag cagattcatc gaatcctgat ttattcaatc cttttccagg ttctccaaac
    46381 atcaattcat gctggtaaag ttgataagtc ttaagttttt gtggttcaaa tcccgtcatt
    46441 ttaccattat gagttgcctt ggaaatactg ggaagttcac tatgtttagg tgtggaagga
    46501 gtaggtggtt ctggagaaac cttagcattt tgtcttctgc cccaaagaaa tcctaatata
    46561 aaatatagta tgtttctgcg atgcttaaaa aagcgcaaca atttctccac ctcctaaaaa
    46621 atatcttatt tagcaatagt cactttactt ggtctaagaa ccctgttatt taacaaatat
    46681 cctttttgca atacttcaac aatattattt tcactttgtt catcagtaac tgctactgta
    46741 ttaacaacct catgcatact tgggtcaatc attccactat tatcaataac ttgtaatcca
    46801 ttcaatgaaa gaatttgcag aagctcttca gcaattgaag taagcaaatc tgatttttct
    46861 tcagatgatt caatacgatc aataacttga agaatctgtt tcataaatgg agcaaatttc
    46921 tcacccttat ctaaatcctg tctatagatt aaatactgct tcaattcttc aatcagacta
    46981 tttttggctt tatcttccaa taaacggcgt gtaattaaag attcgatatc ttcaacttta
    47041 tctacgatat acgaaacttt ttcatgcaat acttcttcac tcataaaaac tttatccttt
    47101 ctttcttcta tttatttgcc atcctttagg gtaattgtaa tacaagacaa tatttgataa
    47161 caatgccaaa cttaatgcgt tactaatcca aaagctatgt acaaacttat caaagaaacc
    47221 actcaaaaac caattggctg caaaaactaa gatgaacatg agacatccca taccttgtga
    47281 atggcgtgtt gtggcataat tgatataatt tttattttca ataaattcat tgtaaaaatc
    47341 attatctata attttatttt caatccctaa actttgtgcc ttggccaagt aagcttctgc
    47401 aatgcgaaca cgcgccttat tatctagaac tgcttcattc tcatattttg ttcgatcaat
    47461 atattttcta aagaaagcct caacgtctgt atcaggtgct tttttcatac gctctatcgt
    47521 gatatctaat agtaacttaa aatacacttg ctggaaatct ttattgttac catagcgttc
    47581 gtttaaggta tctaaataat tctcacactc atcttcagat ttcaaaaata gaatacctgc
    47641 ataatgtagt ttatgctcta gtgaatctga aacatctact aattttcttg caaaattata
    47701 ggcttcttca ttatctccaa tttctctata agagcatgat aaaaggtaat aaatatattc
    47761 ttcattattt ttattttctt ctaaataatg atcatacaga tatcgcacat cttttactgc
    47821 ctgtttatac tgatcaaata aaaatagtga tcttcccttt ttcaaaagat aaaaggaatt
    47881 attagatagt tcaaaagctt cctgataata ctgaattgca aacttttgct gattctgttc
    47941 acaataaaca tcacctagca aagataagat atccgcattt ttaggtctca atctattagc
    48001 ttcactaata gctaattctg catctgataa ctttctatct tcaaggctaa tcatagcctt
    48061 gaaataccaa acatctgcat catttcgatt tatttttaag gcttcttcaa tgtaggaata
    48121 agctaatgat ttctttcctg aataaaaggc ctgtctagct gaatcaagat agcttgaatt
    48181 tgaatgatta gttggagtcg aatcagggac tccttcagaa ctttgtttag aattttctaa
    48241 ttccctatca tatttttgtc tggtttcttc actttcaaat actttttctg cctgtgcaat
    48301 gacttccatc tttctctcag ccattgatct ttgatcaata tttggtgaac ctgtcaactg
    48361 gcgatagcgt cttctatttg acttgatact tttcttaaca tcatctaatg aacttgtttc
    48421 tgaaatccct aactcttcat aatagtttat gaccgacatt gtgttcctcc cctaatcaat
    48481 agttaaatct tttattttac gactagctac ttctacagca cttttatcga gatttgcttg
    48541 tctctctact tcaaaagtcc ctaataagtg attatccgaa tcatgtacct ctacaaaaac
    48601 tgtttgatcg acatcataat gataagttac cttcaaaacc gttcctgcag gccagtcacc
    48661 tggtaattta atggtactct ctcctataac cgtaacaaat tgcggatcct cgtcatcccc
    48721 ttgagtaacc tctactaaca cattttgttg attatctaca actgttgaaa aatactcaga
    48781 gtacttgttt ggtaccttgg aatttttagg aataataatt gtatttcttt tcacaccatt
    48841 cgaaagagcc agagttccca aggcttgaga agtgacatcc gaaacaacta acttttctgc
    48901 taatccacga actgtttcac taacatctgc actttctgat ttattagcga tttccaatgc
    48961 tgcttgaata gctgctcctt gtgctacagc ttcatctgga ttaatagaat atacaatctt
    49021 cttcccaatt ttctcttcca attttctttg taccattggc attcgagttg aaccacctat
    49081 taatagtact tggtcaattt catcccatga cattccagac tcttcaacaa catcatctaa
    49141 cagctcctct gtacgattca ttagactttt tgttgcttct tcaaattcta cacgtgttat
    49201 cggaatttta taactttttc ctttatagtc gagaaagaca tttgtttttt ctacagttgt
    49261 tagtcctctc tttgtattct ctgatttttc acgaagtaag gcagtaaaat gttcatccgt
    49321 ataaatatct tctgctccct gttcttccat cttttcagca ataatcattg ataaggcgtt
    49381 atcaaaatca aaccctccta gattccgatc tccatcggtg gcaataacat caaactcgcc
    49441 atcttttatt ttcattaatg tgacgtcaaa agttccacca cctaaatcat ataccaatac
    49501 tgtctcattt ttttctgctg atataccgta tgcaagtgca gcggctgtcg gttcatttaa
    49561 aactcgtaaa acattaagtc cagcaatttc tccagcatgt ttcgttgctg ttctacgggc
    49621 atcatcaaaa taagctggaa cagttattac aacatcctct actttgtcac caagggcatt
    49681 ttctgctcct tcttttaatc tttttaaaat gattgctgaa atttcctctg ctgtataaac
    49741 agtatcacta ggagaatcaa acttccaatt tggatttccc atttgtcttt tgacatactg
    49801 tacaactgct tcaggtctac ttgctgccaa atttttagct tgaataccaa caagtggttc
    49861 atctttccca tcaaaatcct gaaagaatac aacagatgga gttaaatttt caccatcttg
    49921 attcaataaa atttgtggtt gtccagtctc tgataataca gatactgctg aataagtcgt
    49981 tcctaaatca attccaattg ctttgctcat atttcactcc taatcattat ttgatctaaa
    50041 ctgtgttagt acctctgtta aaaactcaca gtattgtaat tctgcatcaa tcttgctctg
    50101 atttttcccc aaagttctaa gaccgctaac tgttaagtta ctaagttgag ctcctaattt
    50161 ctgacccaat gacaagtccg attctctaat tgcttctctg aatcttttat tatcttctga
    50221 tatatagtat ttttttaatt gtttactctc acctaaagta tctatagtca gaagttgtac
    50281 tgatccttga ttttttaaac gaaaacaaaa ctttacatag tctttctgat gatttgggtg
    50341 cgaaataact agacattctt caatctcttt attgaacaaa ccgccgagtt ttatttgttc
    50401 ttcgtcaatt tgacaaggaa gatcaaactc ttttgctttc tcaacaattt tcgtcttgca
    50461 atattctaaa tccaatcttg gattgttctc atcggaataa tatctccact catctatata
    50521 acttttcaat tctttgtatt taatcatcaa caatctcctt ttatatctta ttgtttacgg
    50581 ttacagtata gcatagcctt cgctcgattt acgaaaagcg tatttatatt tacctttatt
    50641 aaacaattac cccccccccg aaaaagcgta actataatta cttttttcta aaaattccct
    50701 taaaaactgg tagaattatg atagaataga aaaaaggatt cgaggagatt taggatgcaa
    50761 gatgaaagta tttatggatt agtctataag accatccgtg aggaaagagg gtttacacag
    50821 aaggaagctg ctgggactac agtgactcct cattttttac gtcagtttga gcaagggaaa
    50881 tctcgaataa ccattcaaaa atttgaagag attctttcta atattggaat tgataaagag
    50941 acctttgata gtctcaaaac acagatgttt ccaacggaat ttcataaatt acaggctcaa
    51001 gttgctgatt tggcctataa gcgtgaattt aaaaagatca ttagtttgat taatcaaccc
    51061 atggaaaatc ctgggatcgc tgaacactat gtgattgcca atcgtgtagt caataaattt
    51121 gctatcgcaa acatcatcgg cgattctttt ctgactccaa aagattacca agaactagaa
    51181 tatatcaaaa actatctgag tgaattagac gactggaaca aaattgaggt caatatcttt
    51241 tcatctatcc tgcctcactt ttcaatcgaa tttttagatt ataggctcta ccacttatta
    51301 gatactctaa aaaaacagac tgaataccat tcaatccgta ctgctgacta ctatattgcc
    51361 tgcttaagaa ctgctatcaa gcattactct gttaatggct actatgataa agctgagagc
    51421 ttagctgtga aaaccttgga agtgattaat actttccctc tactgagcac caagatgaca
    51481 gagatgatta gtctttccat ggaacgggct aataattttc tcagaaaaga tgatgtcaga
    51541 ggtctagagc ttgctaaaca tatctttgcc agtcttgata actttgaaaa ggtctatcca
    51601 aatcaacttc tgactcgaat gagagaggat ttctttgtta ctgtcacaca actcaatcac
    51661 actggacaac ctttagatgt ctaacctaga aaataaaaaa gcttgaggaa ccacatattt
    51721 cctcaggctt ttcttatcct ttaaaagtga caatagtcgc gccactgcct ccagcatttt
    51781 gtggggcata gccaaaactc ttgacatgtt tgtttctttg taggtatttg gtgactcctt
    51841 cacggatgac acctgttccg ataccatgaa tgatatcaac ttgagccata ttgttaagca
    51901 gggcttggtc gataaaggca tctagctcat tcatggcctc ttcatagcgt ttgcctcgaa
    51961 ggtccagtct ggcttgtgga cctcggccag atgtccgttt aacaacattg acttgtttct
    52021 tcttaactgg cttttcttgc tgaacttgaa caaggtcaaa ctctttctct tccagggtca
    52081 tcttaatcaa gccaacttgg gcttcccagc ggccgtcctt gagttgactg gtcagggtac
    52141 cacgctggcc ataactgaga accacgatat catctcccac ctttggagct cgttttttct
    52201 tggccttttg aaggatcttg tttttagaca aatctacttt ttcaggagcc aattttttca
    52261 gcttggcctt ggcttcaatg atttcgtggg gcttgagttg agatttactg tggagatttt
    52321 tgagaatctg gtcactctca ctgagggcca tgtccacaat ctcagcagcc tgttcacgcg
    52381 ccttattaag ctcggtttcc ttttcacgat tgagttcgtt gtaaagtttt ttgagagcac
    52441 ggttcatctt gagattttct tgctccacct cacggatatt gtccaagcgt ttatgacttt
    52501 caagcgtctg ctcttccaat tgttcaataa tccgattgac atcattgtcc tgatcgacct
    52561 gctggctggc atcccctacg ataacttcag ataggcctag acgtttggca atttcaaagg
    52621 cattacttcg gccaggaaca ccctgcataa agcgataagt cgggcgaaga gttgcagtat
    52681 caaactccat actagcattt tgcacaaagg ctgtctcaat accgtaagcc tttagttccg
    52741 gatagtgggt agtcgccatg gtcttgattt gacgcaggcg aaggtcctcc agaatagcca
    52801 tggcaagagc agctccttct tgagggtctg taccagcccc caactcatcc aagagtaaga
    52861 gtgaatgttg attgaccttg ccaagaatat ccacgatatt ggtcatgtgg ctagagaagg
    52921 tagacaagct ctgctcaata gactgctcat ctccaatatc ggcaaagatt tcttcaaaga
    52981 taccaacacg acttccctta tctgctaaaa tcggcaaacc ggactgagcc atgacctgtg
    53041 tcaagccgag agttttaagc atgatggtct taccacctgt attgggacct gtaatgacaa
    53101 tagctgttaa atcttgacca aaatggacat catttgcgac agcatttttg accaaaggat
    53161 ggcagacatg gagcagttga atctcttgat tttctgacag ctgaggtacg actgcttgcc
    53221 tttcttggat aaagcggacc ttggcacgaa tcaagtctag atgaccgata atccaggcgt
    53281 cattggcaat ctcagccgca tgagggcgga cacgctcaga aatttcttgg agaatgcgaa
    53341 gcatttcata gcgctcatct gctcgcagac tagcaatttc ttcgctcagt ttgactacct
    53401 cacgtggttc gatatagacg gtgtttccac tagcagaaat atcatgaacg acacctgcaa
    53461 tcttattgcg gtaggtgttt ttgactggta aaacctgacg gccatttctg ctagcaacaa
    53521 ttccttctgt caacatctgc gctttttgct tgagcaagtc ttgtaaaaca tcgcgtaccc
    53581 gactctcgct atcatgtatt tttcgacgga ttcgcgccaa ttcttcactg gcaaaatttt
    53641 caatgaaacc cgcatcatta aaggcctgaa gatttccttg taattgcgga aaatcatgta
    53701 atttctcaaa ccaaagggct aattcttcca agctgacatt ttccagattg gcgtaaaaac
    53761 tttgaagttc tcggctggca agaagcacgc gtttcaagag taggaactcc tcgatattga
    53821 gagccgctcc catctccaac ctcttgcaga ctcctgcaat ttccttagtt gagagaatag
    53881 taaaatgcgg ttgctcgacg aaaagagcct gcatttcctt catctcagca aaagcctgtt
    53941 tgattttatc tgctttggca gtcggaccca gctgtctcaa ttgctccaag ccctgctcgg
    54001 tcaacaaatg aggctcaaac aaggccttga ccttatcgaa ctctaatgtt tctaatattt
    54061 tcttattcat ctttatttcc ttgtctttat ttccttgtct ttgaatgtct aggtgtggta
    54121 gctttttaca ttctgataga ttcgagtcaa atctgtaaac aaagggctag gaaaactcct
    54181 gcccttttta tccgattaaa tttgtcaccc agatttgttt gagccaactg gttgttatcg
    54241 gtatgctctg gatgatgtgt tttgcgacga tactcttttc aagaggattt tgtataactg
    54301 ccatggggat ggtcgccaag attgtcaagg ccatttgcaa gacaaataag gtcaccaaca
    54361 tggacaagat acctgctgaa acttggaaca acttaccacc cagttttttg ctaggaatca
    54421 agtgtaagag aagaccaagc aaacgaccaa tgctatagac aatcccaaat acaagcaagt
    54481 agccgatgcc tgcataaaag accttatcca gctgaaagag ttgatccgat gggaaaaaga
    54541 aagtcccctg accttcctgc gaatttgcat aagggagcaa taaatggaat tgctctccaa
    54601 gccccttata aaactggcca gccataaaag ccgatgccat ggctgaaatc aggtaataaa
    54661 cctgtaagag caggcctctc cgatagccga tataaaatcc ccaaaccaag accaatagaa
    54721 gaaggaatga aatcataagg aatcctcaat cttgctctgt tcttgcttac aagtcacaag
    54781 cttgtgacgg agttcttcta gctcttgctc cttatcgtca aattcaatct cacggctgag
    54841 ctgagttgat aaacagttga ctgccaacaa aagagcgatt gtttcatcat ctgcgctagg
    54901 catttgttct ttaattgctt ggtatttttc tgtcgcaacc ttagcgattt cctccataaa
    54961 aaggttatca tgttcgcttg tcaaggttaa cgattttttc ccgaatgtaa atttgaatcg
    55021 atttagattt gccataaaat tcacctcacg atattatacc aaaattcgct aattttgtca
    55081 gtttttacaa attttactgc ttttgtggta caatagaaac tatggcaagt atcacactca
    55141 caccaagcga aaaggatatt caggcttttc ttgaacacta tcaaaccagt ctggctccta
    55201 gcaagaatcc ctatatccgc tactttttga aactacctca agcaacggtt tctatctata
    55261 cttctggaaa aatcttgctt cagggtgaag gggctgaaaa atacgccagt ttctttggct
    55321 atcaagctgt agagcaaacc agcggacaaa atcttccttt aattgggaca gatgaggtgg
    55381 gaaatggttc ctactttggt gggcttgcag ttgtggctgc ctttgtcaca cctgaccagc
    55441 acgacttttt acgaaaactc ggtgtggggg attctaagac tctgaccgac caaaagatcc
    55501 gtcagattgc tcctattctc aaggaaaaaa tccagcacca ggcactcctt ctctcaccca
    55561 gcaagtacaa cgaggtcatc ggagaccgct acaatgctgt ttcggttaag gttgccctcc
    55621 ataatcaggc tatctatctc ctccttcaaa aaggtgttca gcctgagaaa attgtgattg
    55681 atgcctttac cagtgctaaa aattatgaca agtacttggc acaagaggcc aatcgtttca
    55741 gcaatcctat cagcttagaa gaaaaggctg agggcaaata cttggctgtc gcagtttctt
    55801 ctgtcattac gcgtgatctc tttctggaaa atcttgaaaa tttgggacga gaactgggtt
    55861 atcagcttcc aagtggagct ggaacggctt ctgacaaggt ggctagccag attttgcaag
    55921 cctatggtat gcagggactc agcttctgcg ccaaattgca ctttaaaaac actgaaaaag
    55981 cgaaaaaacg cttagaaagg taagttatga attcatttaa aaatttctta aaagagtggg
    56041 gattgttcct cctaattctg tcattactag ctttaagtcg tatctttttt tggagcaatg
    56101 ttcgcgtaga aggacattcc atggatccga ccctagcgga tggcgaaatt ctcttcgttg
    56161 taaaacacct tcctattgac cgttttgata tcgtggtggc ccatgaggaa gatgggaata
    56221 aggacatcgt caagcgcgtg attggaatgc ctggcgacac cattcgttac gaaaatgata
    56281 aactctacat caatgacaaa gaaacggacg agccttatct agcagactat atcaaacgct
    56341 tcaaggatga caaactccaa agcacttact caggcaaggg ctttgaagga aataaaggaa
    56401 ctttctttag aagtatcgct caaaaagctc aagccttcac agttgatgtc aactacaaca
    56461 ccaactttag ctttactgtt ccagaaggag aataccttct cctcggagat gaccgcttgg
    56521 tttcgagcga cagccgccac gtaggtacct tcaaagcaaa agatatcaca ggggaagcta
    56581 aattccgctt atggccaatc acccgtatcg gaacatttta agaaacctaa gaggccgaga
    56641 atcaccaatc tcagcctctt cttctatcgt gagaaaatga ttggtaacta tctaaactta
    56701 ccagaacaga aacacctcaa ctctcaccta ttcatgcaaa ggaattttat ggaagtttat
    56761 ttttcaggaa ccattgaacg gattattttt gaaaatccca gcaattttta tcgcatcctc
    56821 ctcctagaaa tcgacgatac ggacgcagag gattttgatg actttgaaat cattgtcaca
    56881 ggaaccatgg ctgatgtaat tgagggcgaa gactatactt tttgggggca aattgtccag
    56941 cactccaagt atggagaaca actgcaaatc agtcgttatg atcgcgcaaa accaactagt
    57001 aagggcttgg tcaagtactt ttcaagtagc catttcaagg ggattggtct caagacagct
    57061 cagaaaatcg tggataccta tggcgaaaat accattgacg aaattttgca acacccagaa
    57121 aagttagaag gcatcgcagg actctctgcc aaaaatcgcg aggctttcgt ctccactctc
    57181 cgtctcaact acggaacgga gatggttttg gccaaactag ccaactacgg cattcccaac
    57241 aaactagcct ttcagattca agacttttac aaggaagaaa cccttgatgt ggttgaaaat
    57301 tatccctacc agctggttga ggatatcaag ggtttgggct ttaccattgc tgaccaacta
    57361 gctgaggaac taggcatcga aagtcaggct cctgaacgct tccgcgccgg tctagttcac
    57421 agtctttttc aggcctgtat ggaaacaggg gacacctatg ttgaagcacg ggatttgctg
    57481 gaacaaaccc ttactctcct tgagtcttcc cgtcccgtgg aactagaccc cagccaagtt
    57541 gcccaagagc tctcctacct gatcgaagaa gacaaggttc agcagattga taccaagatc
    57601 tttgacaaca gcctcttttt cgctgaggaa ggcatccgca gtcacttggt tcgtatcctt
    57661 gaaaaaggaa aacagaagag tcatgattta aaaaccattc aaaaacatat cactactatc
    57721 gagcaagagc ttggaattga gtatgataac attcaaaaac aggctatctg tgatgctatc
    57781 cagaataagg tctttatcct gacaggtgga cctggtactg gtaagacaac tgttatcaat
    57841 gggatcatcg ctgtttacgc cctgttagag ggacttgact tcaggaagaa aagcaacctg
    57901 cccattcttc ttgctgctcc aactggtcga gctgctcgtc gcatgaatga attgacaggt
    57961 ttgcctagcg cgaccataca ccgccacttg ggaatgacag gtgacgatga taccagtcat
    58021 ctggaagatt acctagatgc tgactttatc atcgtggatg aattctctat ggtggatact
    58081 tggctggcca atcaactctt ctccaatatc tcttctaaca gtaagatcct catcgtaggt
    58141 gacagtgatc agctaccttc tgtcagtcct ggacaggttc tagcggatct gcttcatatt
    58201 cctttgattc ctcagactcg cttggaaaaa atttatcgac aaagcgaaga atcaaccatc
    58261 gtcaccctag ctagtcagat tcgacagggc atcttgccag ctgatttcac ccaaaaaaaa
    58321 gctgaccgtt cctactttga aattgctagt ggccatattc ctgccaccat tgaaaaaatc
    58381 ttaggtgccg ccctcagaaa tggtattcct gcccgtgata tccaagttct ggctcctatg
    58441 taccgaggga cggcagggat tgatgctatc aatcagctca tgcaagacct gctcaatccc
    58501 ccacaaaaag atcaactcag ttttgaagct cctcagtgcc actatcgtaa gggagacaag
    58561 gtcattcatt tggttaacga tgctgaaatc aatgtcttta atggggattt aggagctatc
    58621 acagacctga ttcctggtaa atacaccgaa tcgaaacaag acgagattgt cattgatttt
    58681 gatggtaatg aagtctctta cccccgtaac gaatggtaca agattcgctt ggcctatgcc
    58741 atgagtattc ataagtctca gggaagtgag ttcccagttg tcatcctacc gattactagt
    58801 gctagccgac gtatgctgga gcgaaatctc atctacacag ccattacacg tgccaaaagc
    58861 aaactcatct tactaggcga attacaagcc ttcgactatg ctacccaaca catcggaact
    58921 gcccgaaaaa cctatctgat tgaacgcttc agtgatctac tggagaatgt tgaagaaaag
    58981 caacaagctg tctctgaaac agtcacatca agtgcctctg aacaatccta catcctaacc
    59041 gaagaaaact gggacagcat tccagccatg attgggatta cagacacaga cctcaaagag
    59101 atttttggaa aatagtacat cagaaaaccc accaattcag gtgggttttc tgtttattaa
    59161 gattatttta ctgttgctgt gcttgtgatc aattcaacag cttttttgat agtgatatca
    59221 tgtttcaaca tgtcagctga aagcaagttt tgaacttgtg caacttccat gttgtagtct
    59281 gctgccaatt gctcaacttc tttttggatt tcttcttctg aagcatcaaa tccttcagct
    59341 ttggcaactg cttcgataac aaggttagtc ttagtacgtg actcagcttc tgcttggtat
    59401 tggttgtgaa ggtcttcttg agtagttcca gtgatttgga agtacatgtc agggttgatc
    59461 ccttgacgtt gcaagttccc aaggaattca tttactgaac ggtgaacttc ttcatggatc
    59521 atttcttctg gaagttctac gatttcagcg ttttctacag ctgtatcaat tgctgcacct
    59581 tcaactgcat ctttgtaagc ttcttcttta gcagcagcca attctttgcg gtatttttct
    59641 ttcaagtcag caagtgtttc aacttcttca tcaatgtctt ttgcaagttc atcgtcaaga
    59701 gctggaactt ctttagcttt tacttcgtgg atagttgtca cgaatttagc ttctttacct
    59761 gcaaggtctt ctgcttggta gtcttctggg aatgttacga taacatcaac ggtttcgcca
    59821 gctgagtgac ctaccaattg gtcttcgaaa ccagggatga attgacctga accaagtcca
    59881 agtgagaagt tttcaccttt tccaccgtca aattcaacac cgtcgataga accaacgaag
    59941 tcgatcacaa cagtgtcgcc gttttcagca gcagcttcct tgataaccaa ttcagccaga
    60001 ttgttgcgtt cgcgttcgat acgctcttca acatcagcgt cagttacttc tttttctaca
    60061 tcaactgata cttcaaggtt tttgtagtca cccaatttta cttcaggttt tgtaacgact
    60121 tcagcagcga taacccagtc ttgacctttt tccattgaag ttacgtcaat ttttggttgg
    60181 gcaaccactt caagaccagc ttcttttaca gctgcttcat aagcgtttgg caaaagagcg
    60241 ttcataacgt cttggtaaag tgattcttca ccaaattttt tatcgaagat aggacgtgga
    60301 aggtgacctt tacggaaacc tggaacatta agagatttct tcactgactt gaagacacgg
    60361 tccaattctg gtttgatttg gtcttgagag atagtgaaag tcaagacacc acggtttgtt
    60421 tctttgtttt caaatgatac agacattctg tcatttctcc ttaaaatttt ttaaatacag
    60481 tctattataa cattttctat aaataaaatc tagactaatg cagacaatta tagacaacaa
    60541 gcctttttcc taactaaaac actcataaag tatagacaat tttagactac tttggatatc
    60601 ttttggttag tcattttcca aaactaattt atctaatttt taagttatat ttgacttcat
    60661 cttctcagta acatgagtat aaacacttaa aatctttgtt tcattagtat aatctacacg
    60721 atccattatc gctattatag gtacttccaa ttcagcaagc aaacttatat gcgaatatct
    60781 aaaaacatga gcagtcaata caaaatcatc tttcttaatt tcacttttcc taaacctgtt
    60841 tttcaaaaag taattgaaac aagttatcat taagggagaa ccattatttg taaatatata
    60901 atcaccttct tctaaaagaa gatattcttt taaaatttct aacactctat cactaatacc
    60961 aattactcta tatgaagcta aacttttcgg actatccaaa aacacttcgt tattggacga
    61021 ttacattata gtaaaacgaa ataagaacag gacaaatcga tcaggacagt caaatcaatt
    61081 tctaacaatg ttttagaagt agaggtgtac tattatagtt tcaatctact atacaagacg
    61141 aaattgaaga aatctttcca ttataaaacg catattatca aggtttttaa acacctaata
    61201 atatgcgttt tttcctattt taaagacttt tatccaccta ttatacaaag ttaagtatcc
    61261 atcacagttt acaattagcc ttcattacct aacccattca ccatccttca agagagtaac
    61321 ctttaagaac cgaataaata aatggcaaat ttcgttcatt taatttaact gcactgttaa
    61381 tttgattagc tccatctcct aaagtatgca ctcctactac gcggtgacta gcatcataaa
    61441 ctgcagatcc actagacccc tctaaagtat caacttggta atccaagaac atgccatcat
    61501 cacttaaaac ttgtttttta tctgtataca tttgatgaat tttaaaatta tatgatagat
    61561 agcctgtgat agtcacagtt attcctgtca aatttttttg actagtagga agacccaaag
    61621 tccctaattt tgcaccaatg ggctcttcta gaattaataa agccaagtca tattcccttg
    61681 cattcttaga atttaaattt ctaaattcct tcaaataacg aacttccttt actttgatct
    61741 ttccaaatag ttcttgactt ggactaacag ccggaagaac ataaatatca tccgcttctt
    61801 tcccatagtc atgtctgtag tagttgtgag ccgctgtaat taacacatta tctttaataa
    61861 aattcgcact tcccctccct tctacattca ttccatcggc tactccataa tacttagata
    61921 aaaccatagc tgaagtcgaa tacggatact gtaaagtatt atcaatttta atcaaatcat
    61981 cattaccgat aatacttctg attgcttttg gtagtatgaa ccatacgttg gtgaaatctc
    62041 agataatgaa gaatcattag actctggacc tttttctagt gtctcactta cctcatattc
    62101 ttcacctgta ctagaaataa cactcaaagc agatactgtc gataactggc tagccaataa
    62161 agtactcgca ataattgaaa tacccaattt tttataaaca gttttcttca ttattgtatc
    62221 ctcctaatgt aattatagcg tactattcta aatttcttaa tctactatag aatcaagaaa
    62281 tctaccacct tctttaaata ccctccatta tcacataaac aggtaaactt ttcaattaat
    62341 gactgcgctt ttcaatcacg ctagaggtac ttacttgctt ctttgatact aagttcagcc
    62401 attctttcct tgtttttctc aataaagcat gttacccaag tgggattcgt tttggagtag
    62461 tctcgcagag tccagccaat ggctttattg ataaaaaatt ctgtttggtt caagttatga
    62521 agtagaatct tttccattaa ttgagtattg gtcttctctt ttattaacaa ctggtggtca
    62581 atagcgacac gtctcagcca gatattatct gataggctcc attttatact caatgaaaat
    62641 caaagagcaa actaggaagc tagctgcagg ttgctcaaaa cactgttttg aggttgcaga
    62701 tagagctgac gtggtttgaa gagattttcg aagagtatta agattatttc ttctagttca
    62761 gggtgttcat acaccaaact ccctactact cgatctagga tatctaccgt gtcccaccag
    62821 gattttgtca cgactaactg ctctagctta ggcaaatcgg tttcctttag ataagactgc
    62881 attgctttca aatagttagc agccacatat tggtattttc taggctcctt ttcccagcaa
    62941 gtgtctgcaa aatcccaatc gataatcttt gtttttttcg cttctggtaa atatttttat
    63001 agagtttatt tctttcaggc accgcaatac ctagaaaaga aaattgatgg cgcatatagg
    63061 cttccatggg ccttgctttt tagagtcttt tgctgcttct agctcctaaa gtaaatctgc
    63121 taaactcatc taaaactcct catgccccac caaatggtgc tgaaaggcgt agacagccgc
    63181 ctgggtacga tcgctgactt caagtttggc aagaatgttg gacacgtggg tcttgaccgt
    63241 cttgagagag ataaagaggt catctgcgat gcgctgattt tcgtagccct tggcgatgag
    63301 ttggagaaca tctcgctcac gcgcagtcaa ttcttcatga agttccatat gattgcggtg
    63361 gtattcaacc ttcttgctaa cctcttgctc aatggccagc tcgccagcag ctaccttact
    63421 gacggcatga agcaattcat ctgcactaga agtcttgagc atatagcctt tggcaccagc
    63481 atctaagact ggcatgattt tttcattgtc caaataagag gtcacaatca aaatcttggc
    63541 ttcaggccat tctttgagga tagccaaggt cgcatcaatc ccattcatct caggcatgac
    63601 aatatccata acaataacat ccggacgcag ttccaaggcc aagtcaatcc cttgagaccc
    63661 gttggacgcc tcacccacaa cttctacatc ggcttggagg tcaaagtagc ttttcaagcc
    63721 caatcggacc atttcatggt catctactag taaaattttc atctttactc ctttatcatt
    63781 ccttatctaa caggggaata cggatatcaa ctgccagccc ttgcttggga gctgttaata
    63841 actgaaccgt ccctgccata tcttcaaccc gctccttgat atttcgcagt ccataactca
    63901 agtcgtctaa gctccctaac tggaaaccaa tcccattgtc caccaccttc agttgcaatt
    63961 caacatctgt ctgatagagg tagacatcta ggcaagatgc ctgggcatgg cggagggtat
    64021 tgctaatcaa ctcttgcagg atacggaaga tatgctcctc gattttctta ggcaatttcg
    64081 tcatattctg cttgagacta accctaagat cactcttgtc ctcaagctct tttaagagaa
    64141 tctgaatccc ttctatcaag ctcttctgct ccagttcaac tggtcgcaaa tgcaagagca
    64201 aaacccgcaa atccttctgg gcagtttcta aaatagctgt gacactctgc aactggatct
    64261 gcatcttttc tctatccaat ttcaaagcct gctgactgat acccgataaa atcatgtggg
    64321 ccgcaaacaa ctcctgactg actgtatcgt gcaaatcccg agcaattcgc ttccgttcct
    64381 tctcgatgat ttcctcttcc tgagcaaggc tatgattttc agctttttga agagcctctg
    64441 tcaaaaggtt aagtttacct gataaggact tgaaactggc atccaaatct ggatctgcaa
    64501 cctgaaccac ttcttgccct gctaataaac gcttgagatt agcctgcatt tttcttagag
    64561 aaagctcttc gatccctcgc caaaacaggg ctaagagaca ggtcatggac atgctgaaaa
    64621 ccaacaataa aaagacaaat ttttctgttt tttcgacatc gtgcaaaaag atagaccagt
    64681 caaaatcaag tatttccagc aagctgtggg agaaaaaaaa gacaaatagg aaggaggtga
    64741 gagcaataat gacataggct tgttttttca tcctctaacc acctccacat caccaatcat
    64801 agtggtcaag aaaatcttga cactcttgtt actcttgaga tagtcttttg tttcttgatg
    64861 atagtgttca ttgcggaggg ctcgcttggg ctggttgaaa aaagtcaaat ccccatagag
    64921 acagttaacg ctgagactga cttccacatc tacaggtacg atgattttgg tcgttcctac
    64981 catctttctg aggataatga cattgtcatg attggttaag atgaccctct ccagatgaat
    65041 agtgtccttg cccatgaagc gaaagagatt gatatcatcg aattggcaag tctggtagct
    65101 tgaaaaatga tgaagatttc caaaccaacg atttttctcc ttcttaaccg tcacgacctc
    65161 ttcaaaaacc aaattggtct gctctttttc ctggttcatc atcgggtaaa gaagaaagag
    65221 gctatagata accgcaacaa aaatagctag aatcacaaaa ggattgagca taacgatgaa
    65281 aaagaagaga atggttaccg ctactaaaag aagattattt ccctctttac cagtgtagta
    65341 gcgaatcaaa agcaaaaaga ggaatagtat cagcagaaaa cgcgaaaaat gctctgatac
    65401 catcaaaatc agagctcctg tcagaagaca ggcttcgata aataaaaaga ttttaaattt
    65461 tctcataggt tcatcctctc ccttctattt tatcacaatt caaaaaagtc acctcagtct
    65521 gaggatggaa aaaaggcgct ggttacgcct ttttcatctg atcctttgct tcttttaatt
    65581 ttccataaag aagatagtct actttttgta gatctgctat ggtggcacag ttaagggaac
    65641 acataatcaa gcgtaggtct gctttccagc cttggacaat gccaatcact tcttcaactg
    65701 tgtaggtttc aaccaattcc agaacggttc gtgacaatcc cacagcctta gcaccaaaaa
    65761 ccaagcactt aatcatatcc agcggattcc gaacccctcc actaaccaag agttcgacct
    65821 tatctttcca ttcttgggca ttgagaaggg cctgcatggt agactgaccc cattgattga
    65881 ggtaatcacg ctggccacta cgacggtttt cgatataggc aaagctggtg ccaccacgac
    65941 ccgataggtc cactgtacga acaccgaatt cataggctct ttcgattgtc ttggcatcca
    66001 ttccaaagcc cacttccttg aggacaatag gaacgggaat ttgcttgcta taatctgcta
    66061 gatgcgattg ccagcttcta aacttccttt ctccctcggg catgagtaat tcctgcatga
    66121 cattgacatg cacttgcaat agaacaggat tcatctcttc tacagtctga agtcctaact
    66181 cgacaggctt gtccaatcca atattggttc caaggaggag attgggatga ctagacttga
    66241 cagaaaaaga atcatccgtt ggatttttga gggctgcgct ataagaaccc gttacaaata
    66301 aaataccaca ggattccgcc acctgagcca gcttttgatt gatttctctt cccttattac
    66361 ttccaccagt catggcattg atataaaaag gaaagtccca ctttcgacca gcaaactctg
    66421 tcgaaagatc gatttcatcc agattgtaaa gaggcaagga agaatgaatc agctccacct
    66481 catcaaagct attataggaa cttttctgct caagggcata gaggatatgc tcgtccttac
    66541 gatttgtcgt catgtcctat cctttcttga tataagagct caatccccag atcggcccaa
    66601 cgatttttta aggttttggt tgattgcgca tcaaaactca gggcgatgcc acagtcacca
    66661 ccaccagcac cactactctt ggcaacggcc tgcaaatctt gactggcttc tttcaactgt
    66721 ctaagcaaag gcgtgtaaat atctgtactc aagccttcta aaagcttgct ggctacttct
    66781 acttgctcga taatcttttc tgatttcccc tgttccaagg cttcgaccaa agaaaccacc
    66841 gtttcttttg aggaacttaa aaaattttga ttgatatttt gcttgatttg ctggaccatg
    66901 tgactcgata cagccacttc cttggtccat cccactaaga aatcacattc taaagttggt
    66961 ttcacttgtg aaattgaaaa gccccaatca cgctccagaa ctgtcgccaa gttttcttct
    67021 tctaaccaag cagccacctt ctggcgatca aatgactggt agagaaccaa atcctctgcc
    67081 acaatacagg caaggtcgcc catggaacca ttgtctcctc gcttgagcaa gacagcgcta
    67141 gtcagcttga acaagagctc ctgatcaaca gaaacatcat acagagccag taaagccttg
    67201 acaaccaaga caacgacgct gccactagaa cctagaccaa actttttccc ttctcgttcc
    67261 attttgccac agatttctag agaaaaaggt cttaaattct gaccacgaac agcgaggaag
    67321 tctcccatca aagcaatcgt ttcttgaatc aagctgtagt cagaattagg ccttaagtcc
    67381 actgcgaaat caaacatatc tgaatagata cggtagctgt cagaaaaagc aatctcagcc
    67441 ctcatataga tgggaatatc ctttatcaaa gctaactgcc ctggctctaa aatagcatat
    67501 tcacctgccc aatagagttt tccgcaagtt ttaacagcaa tcatcttgac tcaaatcctt
    67561 tgtttttgac acaatcaagc gataacgatg accgaaaatt tctgataaat gctccaagtc
    67621 tttctcctga cagaagacct taacattggg accagcatcc atggtaaagt agcaggcctc
    67681 tcctttctca cgaagctggc gaacaaagtc catagcctca taagaggcat ccgtcagata
    67741 agaaaaggct ggactagcag tctttgtcgt agcatgcata gccagggcat ttttctccgt
    67801 taattctcca atcttggcaa aatcattttc cttgagataa atcagcatat cctgatagtc
    67861 cttctcagac tgacgaaccc agtcgtcaaa agtcgtcgag gtttccacac aaagtttcat
    67921 cccgtcacgg ctagagattg gttttttctt gtcctctagc accaacataa tcatagctag
    67981 tttcaagtct gtctctacag ggtaaatttc tccactatcc ttatcccagg ctcctagtgg
    68041 tccataaaaa ctccgagaag aagagcctga ggcaaatttg gcttcctgtg ccaactgact
    68101 tctatccaat ccaagcttga aataagcatt acaagccttg accagggcgg acaaaccact
    68161 agaacttgag gacaggcccg ctgcagtagg catattgttt tgagtatcga tacggacaaa
    68221 gccctcacca gctggacgat aacggtcaat aatcttactc atcttggcat gctcgacctc
    68281 attttgtagc tgaccattga tgtaaaattc gtcagctgtt acattggctg gtaaaggcga
    68341 caaggtcgtc tctgtataca tattttccaa agttagagaa atactgctag tagcaggcac
    68401 catctctttt tcttttttct ttccccaata tttgataata gcaatatttg cgtaggaacg
    68461 tactgttaca ggctctctat ccatgtctga acagctcctt tctcttctaa tctttctgct
    68521 agttcttgtg cgtgtgtcaa attggttacc aaggctatga tacaacctcc tagcccacca
    68581 ccgctcatct tggcacccag agcaccatgg ctaagagtcg tttcaaccaa aaagtctgcc
    68641 tcagggctac tgactccaat ttcttttaaa tgtaaatgcg cttgactgag gatttgtccc
    68701 agtccttcag catctttttg tgaaatcgca acttctgctt gctgggttaa ttctcccaag
    68761 gcatgcaaaa acggtagggc atccttgccc ttattttgaa ccacttggat ggcttcacga
    68821 gtatgaccat aaacacccgt atcggcaatc accaaatagg cggataaatc catctcaagt
    68881 tctgtaaatc ctacgttctt gataaagcga ataggttggt cactgagaca ggtcttagca
    68941 tccaaaccac taggattcat atgggcaatc atttcagctc gattgaccaa gatttctagt
    69001 acatcatgag gcagatcagc ctgatagtag tcaaataccg cacgaatggc cgctatgctg
    69061 atagccgctg acgaacccat cccccgtttc tcagggatag ccgagtcaat ctcacaacga
    69121 atgcaggctt ctgtgatatc caaatactcc agtgaggcat aaaccgccat ggacaaggta
    69181 tcctcctcat aaaggcgcca aggactctct gcaggaacta ccttacaggt cacctccacc
    69241 tccaaaagag gcagggaaat ggcaggataa ccgtaaacga ccgcatgttc ccctattaaa
    69301 attatcttac tatgtgcctg accgacacca actttttttg tcattttttc cttttactag
    69361 acgaaaaaac gtcttatttt tcatacaaat attaattctt tcctatctat tttattatat
    69421 tttcacaaaa aaagcgattg tttccattca caatcgcttc tttcattatt gaacccattc
    69481 gccattatag ttgacagaat agccatctac ggtcgtattc actgccaagg cacctgagct
    69541 ataagcgtag taccatctgc cattgacctg gaaccaacct gtcgtcatag aacgacgaaa
    69601 gaaactccat accattaagt aaagaggaaa gtcgtgaggg agcatgcgcc attgacaacc
    69661 tgttttagtg acgtacaaag tatcattaac aagtactcgt ttcggccatt tataggtgcg
    69721 gtgtttggag aaatagggtt caatcttcgc ccattcttga tcgtttaaat cagtatcata
    69781 tgctttacgt atcataactc tagtttaaca tttttttgtg aatacaggtt ctaaataatc
    69841 gaccacgaaa atttcttaag tggaaaacgc cttatgaagt atgctacggg aaacttatgc
    69901 acttaatttg acaattcaag atgtaaaaat atatactata gtagattgaa actagaatag
    69961 tacacctcta cttctaaaac atttttagaa atcgatttga ctgtcctgat cgatttgtcc
    70021 tgttattatt tcattttact ataatatttg ataagttatc ctaaaagtgt tatta
//
LOCUS       DBEJHE010000010        64529 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC4 isolate 671759
            SAMN38261586-rid24793303.denovo.10, whole genome shotgun sequence.
ACCESSION   DBEJHE010000010 DBEJHE010000000
VERSION     DBEJHE010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261586
            Sequence Read Archive: SRR26833752
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 64529)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 64529)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576136.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576136.1
            Genome Coverage       :: 109x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 19:48:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,067
            CDSs (total)                      :: 2,029
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 131
            CDSs (without protein)            :: 131
            Pseudo Genes (ambiguous residues) :: 0 of 131
            Pseudo Genes (frameshifted)       :: 64 of 131
            Pseudo Genes (incomplete)         :: 59 of 131
            Pseudo Genes (internal stop)      :: 46 of 131
            Pseudo Genes (multiple problems)  :: 32 of 131
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..64529
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261586-rid24793303.denovo.10"
                     /strain="GPSC4"
                     /isolate="671759"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(184..1806)
                     /gene="groL"
                     /locus_tag="ACL3EZ_000848"
     CDS             complement(184..1806)
                     /gene="groL"
                     /locus_tag="ACL3EZ_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166362.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0140662 - ATP-dependent protein folding
                     chaperone [Evidence IEA];
                     GO_process: GO:0042026 - protein refolding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HGR0392447.1"
                     /translation="MSKEIKFSSDARSAMVRGVDILADTVKVTLGPKGRNVVLEKSFG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     IKNVTAGANPIGIRRGIETAVAAAVEALKNNAIPVANKEAIAQVAAVSSRSEKVGEYI
                     SEAMEKVGKDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDSEKMVADLENPYI
                     LITDKKISNIQEILPLLESILQSNRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITEDLGLELKDATIEALGQAARVTVDKDSTVIVEGA
                     GNPEAISNRVAVIKSQIETTTSEFDREKLQERLAKLSGGVAVIKVGAATETELKEMKL
                     RIEDALNATRAAVEEGIVAGGGTALANVIPAVATLELTGDEATGRNIVLRALEEPVRQ
                     IAHNAGFEGSIVIDRLKNAELGIGFNAATGEWVNMIDQGIIDPVKVSRSALQNAASVA
                     SLILTTEAVVANKPEPVAPAPAMDPSMMGGMM"
     gene            complement(1822..2106)
                     /gene="groES"
                     /locus_tag="ACL3EZ_000849"
     CDS             complement(1822..2106)
                     /gene="groES"
                     /locus_tag="ACL3EZ_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HGR0392448.1"
                     /translation="MLKPLGDRVVLKVEEKEQTVGGFVLAGSAQEKTKTAQVVATGQG
                     VRTLNGDLVAPSVKTGDRVLVEAHAGLDVKDGDEKYIIVGEANILAIIEE"
     gene            complement(2279..2674)
                     /locus_tag="ACL3EZ_000850"
     CDS             complement(2279..2674)
                     /locus_tag="ACL3EZ_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HGR0392449.1"
                     /translation="MYNKVILIGRLTSTPELHKTNNDKSVARATIAVNRRYKDQNGER
                     EADFVNMVLWGRLAETLASYATKGSLISVDGELRTRRFEKNGQMNYVTEVLVTGFQLL
                     ESRAQRAMRENNAGQDLADLVLEEEELPF"
     gene            complement(2752..3513)
                     /locus_tag="ACL3EZ_000851"
     CDS             complement(2752..3513)
                     /locus_tag="ACL3EZ_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HGR0392450.1"
                     /translation="MAKNVVITGATSGIGEAIARAYLEQGEDVVLTGRRIDRLEILKS
                     EFAVSFPNQTVWTFPLDVTDMVMVKTVCSDILETIGRIDILVNNAGLALDLAPYQDYE
                     ELDMLTMLDTNVKGLMAVTRCFLPAMIKVNQGHIINMGSTAGIYAYAGAAVYSATKAA
                     VKTFSDGLRIDTIATDIKVTTIQPGIVETDFSTVRFHGDKERAASVYQGIEALQAQDI
                     ADTVVYVTSQPRRVQITDMTIMANQQATGFMVHKK"
     gene            complement(3546..4175)
                     /gene="ytpR"
                     /locus_tag="ACL3EZ_000852"
     CDS             complement(3546..4175)
                     /gene="ytpR"
                     /locus_tag="ACL3EZ_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtpR family tRNA-binding protein"
                     /protein_id="HGR0392451.1"
                     /translation="MIFTYNKEHVGDVLMVIVKNSGDAKLNVERKGKVARVFLKKENG
                     ETVAWNIFEVSSLFEIAERGQVFLSDEQVARLNQELQAEGFTEEIVNDKEPKFVVGEI
                     VEMVAHPDSDHLNICQVAVASDKIVQIVAGAPNARVGLKTIVALPGAMMPKGNFIFPG
                     ELRGEKSFGMMCSPRELHLPNAPQKRGVLELSEDQVVGTPFDPAKHWTA"
     gene            complement(4191..4508)
                     /locus_tag="ACL3EZ_000853"
     CDS             complement(4191..4508)
                     /locus_tag="ACL3EZ_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000615765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HGR0392452.1"
                     /translation="MIQPASLEELASLVEKAGKKVFLFVADWCGDCRYIYPALPEIEE
                     TNPEFTFIRMDRDQYMDLAKLWDVYGIPSLVVLEKDKEIGRFVNRDRKSKEQINDFLA
                     GLK"
     gene            complement(4505..4804)
                     /locus_tag="ACL3EZ_000854"
     CDS             complement(4505..4804)
                     /locus_tag="ACL3EZ_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4651 domain-containing protein"
                     /protein_id="HGR0392453.1"
                     /translation="MNGMKAKKMWMAGLALLGIGSLALATKKVADDRKLMKTQEELTE
                     IVRDHFSDMGEIATLYVQVYESSLESLVGGVIFEDGRHYTFVYENEDLVYEEEVL"
     gene            complement(5002..5082)
                     /locus_tag="ACL3EZ_000855"
     CDS             complement(5002..5082)
                     /locus_tag="ACL3EZ_000855"
                     /inference="COORDINATES: protein motif:HMM:NF039231.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0392454.1"
                     /translation="MASSGKMFRNTYTPDGYYVGNLGAWQ"
     gene            complement(5089..5280)
                     /locus_tag="ACL3EZ_000856"
     CDS             complement(5089..5280)
                     /locus_tag="ACL3EZ_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein"
                     /protein_id="HGR0392455.1"
                     /translation="MYYSVDDVVSNAFKKRMILDSFFAFNCSGTMKVSTWVYDKGEWY
                     YVSSSGSMIANDWVKDNGK"
     gene            complement(5441..6115)
                     /locus_tag="ACL3EZ_000857"
     CDS             complement(5441..6115)
                     /locus_tag="ACL3EZ_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0392456.1"
                     /translation="MKKKAFGIVLLVLAAWILLQGNFGIPSLDGKIWPLLGIVFFAYK
                     SIESILRRHLTSAVFTGLLALIIANYAYDLLPVTNHSLIWASILVVLGVGYLTHSSKF
                     WNEKKWWYNGKKTVVTAKEVAFGSGTFYKQDQDLVDDQVEVAFGDAKIYYDNAEMLGD
                     FATLNIEVAFGNATVYVPQHWRVDLKVETSFGAAKADAPVAPTSKTLTIRGDVAFGKL
                     EIVYVK"
     gene            complement(6121..6567)
                     /locus_tag="ACL3EZ_000858"
     CDS             complement(6121..6567)
                     /locus_tag="ACL3EZ_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family DNA-binding domain-containing
                     protein"
                     /protein_id="HGR0392457.1"
                     /translation="MKLRIEIDGNLEETEIVIKTPTLTDEIADLQRLLQESKAPRLTF
                     YKGTGEYYLDLSEILFFETEGSKIYAHNQKEAYEVRLKLYELESILPRYFNRVSKSTI
                     ANIRQIYSVDKSFSGTGTISFYQTHKEVHVSRHYQSLLKENLRNMR"
     gene            complement(6681..7184)
                     /locus_tag="ACL3EZ_000859"
     CDS             complement(6681..7184)
                     /locus_tag="ACL3EZ_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HGR0392458.1"
                     /translation="MKNYQEWYRNISSRLTSRPILLFLLRSFNRLMTVAMPLVYLILL
                     VTTYLQLGLGQQVGVYVLIPASGFVALSLFRKKINHPRPYETWDICPLLDKDSSGRSM
                     PSRHVFSATIISVACLHASLPIGLVCLIFSALLGLVRVLGGVHYPKDVLVGYACGLVW
                     GFLFFLF"
     gene            complement(7181..7543)
                     /locus_tag="ACL3EZ_000860"
     CDS             complement(7181..7543)
                     /locus_tag="ACL3EZ_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HGR0392459.1"
                     /translation="MSQKLYNMKFAAVYLALIAKVERKGGKAESVHQVTSWLTGYEVS
                     DVLACLDRDVTYGDFFRQAPYYVPERIAITGKICGVRIEEIDDPLMQEIRRLDKLVDW
                     LAKGKTSQQVLEKYEKHK"
     gene            complement(7609..8640)
                     /locus_tag="ACL3EZ_000861"
     CDS             complement(7609..8640)
                     /locus_tag="ACL3EZ_000861"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0392460.1"
                     /translation="MGFLLMGALFIVLPRTMVSAKRINQVLYLHSSIQNPVQVQLTDE
                     NFKGQVEFKDVTFRYAANSEAVIEHVSFKAETGQTVAFIGSTGSGKSTLVNLIPRFYD
                     VSAGEILVDGVNVQDYDFSATAHAGQKVAIVGPTGTGKTTIVNLLMKFYEIDKGSIHI
                     DGVDTKAMTRSEVHDAFSMVLQDTWLFEGTIRDNLIYNQIGISDERMMEASKAVGIHH
                     FIMTLPDGYDTILDDTVTLSVGQKQLLTIARALLKDAPLLILDEATSSVDTRTEELIQ
                     KAMDRLMEGRTFFVIAHRLSTIRNADLILVMKDGNIIEQGNYEELMAQGGFYADLYNS
                     QFTEDEAEE"
     gene            complement(8647..9468)
                     /locus_tag="ACL3EZ_000862"
     CDS             complement(8647..9468)
                     /locus_tag="ACL3EZ_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0392461.1"
                     /translation="MILLAILFTCFSVYLELEVPTYISKITDLLGSQGTNLDELWQPA
                     SMMMGMLFLAFLSVVAVGFFASRVAASYTSRLRSDIFNRVLDYSQTEIKKFSIPSLLT
                     RTTNDITQVQMLITMGLQVVTCGPIMAIWAIGKILGHSEYWLWAVLVAVIVNVLMTTV
                     LMTLAFPKQSLIQGLTDKLNSITRESLTGIRVVRAYNAEDYQNEKFAAVNDELTRLNL
                     FVNRLMAILNPIMMGISSGLSVAIYWIGAYVINDAAPIARLPLFSDMIVFMSYAM"
     gene            complement(9484..9954)
                     /locus_tag="ACL3EZ_000863"
     CDS             complement(9484..9954)
                     /locus_tag="ACL3EZ_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HGR0392462.1"
                     /translation="MGKPMLVFKRFGHQIHLMVQKEAKRCGIEFMGGPQGQVVRFLDN
                     REKNQDLVLIKDIEQELNITKSVASNLVKRIVQNGLVELEASPVDKRAKFVRLTDKAR
                     SQMQQVKAFFERIDKQLMEDIDEDELLIFEKVLGQLQANIKGIGGENKEISQKN"
     gene            complement(10078..10794)
                     /locus_tag="ACL3EZ_000864"
     CDS             complement(10078..10794)
                     /locus_tag="ACL3EZ_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGR0392463.1"
                     /translation="MGRKWANIVAKKTAKDGANSKVYAKFGVEIYVAAKKGDPDPESN
                     SALKFVIDRAKQAQVPKHIIDKAIDKAKGNTDETFTEGRYEGFGPNGSMLIVDTLTSN
                     VNRTAANVRAAFGKNGGNMGASGSVSYLFDNKGVIVFGGEDADAVFEQLLEADVDVDD
                     VEAQEGTITVYTAPTDLHKAIVALRESGIEEFQVTELEMIPQSEVELSGEDLETFEKL
                     YSVLEDDEDVQKIYTNVDGF"
     gene            complement(11677..13092)
                     /gene="ply"
                     /locus_tag="ACL3EZ_000865"
     CDS             complement(11677..13092)
                     /gene="ply"
                     /locus_tag="ACL3EZ_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cholesterol-dependent cytolysin pneumolysin"
                     /protein_id="HGR0392464.1"
                     /translation="MANKAVNDFILAMNYDKKKLLTHQGESIENRFIKEGNQLPDEFV
                     VIERKKRSLSTNTSDISVTATNDSRLYPGALLVVDETLLENNPTLLAVDRAPMTYSID
                     LPGLASSDSFLQVEDPSNSSVRGAVNDLLAKWHQDYGQVNNVPARMQYEKITAHSMEQ
                     LKVKFGSDFEKTGNSLDIDFNSVHSGEKQIQIVNFKQIYYTVSVDAVKNPGDVFQDTV
                     TVEDLKQRGISAERPLVYISSVAYGRQVYLKLETTSKSDEVEAAFEALIKGVKVAPQT
                     EWKQILDNTEVKAVILGGDPSSGARVVTGKVDMVEDLIQEGSRFTADHPGLPISYTTS
                     FLRDNVVATFQNSTDYVETKVTAYRNGDLLLDHSGAYVAQYYITWNELSYDHQGKEVL
                     TPKAWDRNGQDLTAHFTTSIPLKGNVRNLSVKIRECTGLAWEWWRTVYEKTDLPLVRK
                     RTISIWGTTLYPQVEDKVEND"
     gene            complement(13103..13513)
                     /locus_tag="ACL3EZ_000866"
     CDS             complement(13103..13513)
                     /locus_tag="ACL3EZ_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0392465.1"
                     /translation="MIKRGDVVALYLPFPTISSDLAVKNHMYICIDNSMTKNKELVKN
                     QTFKPALLTRRLVKNFMIEEPDLARNPFTRPTLIDLDKVFMLDNTVIPTSYLARRRRN
                     VSEELYEEILDYLVQPRLISLNKSEFMQLNPGTY"
     gene            complement(13506..14114)
                     /locus_tag="ACL3EZ_000867"
     CDS             complement(13506..14114)
                     /locus_tag="ACL3EZ_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0392466.1"
                     /translation="MSQSSYLSPLLWLKKEADKEKMSATQCQIFFFYYQMFELLFARE
                     SDMKDLCLGTKGFYFSQLEKNLLSGVSRFLKNLEGKVTLKANQEVSARKALFLALTTS
                     QSDWQELAPVFDFYQTIGRLENPSLLSSQDRQHLMWIYQSALEKDYIVKVIGDKHFVL
                     KRQDATKLTARQTQTLEILSQSEDLVNPVYVTLGEKGVLLLD"
     gene            complement(14127..14585)
                     /locus_tag="ACL3EZ_000868"
     CDS             complement(14127..14585)
                     /locus_tag="ACL3EZ_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000186958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HGR0392467.1"
                     /translation="MTPEEMYLTERLDVQIAHFLKKSVQHRRRYKVLKITEIVAGFLI
                     AVFCAIPMPGDRYRLISVALSSLGLLCEGIINLYNAKENWISYQKTAQLLEKEKFLYQ
                     CQTEKYAGKTKAFALFVKTCEGLISEEINQWESIQSKEVAASADAPVKKE"
     gene            14710..15163
                     /locus_tag="ACL3EZ_000869"
                     /pseudo
     CDS             14710..15163
                     /locus_tag="ACL3EZ_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            complement(15840..16100)
                     /locus_tag="ACL3EZ_000870"
     CDS             complement(15840..16100)
                     /locus_tag="ACL3EZ_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0392468.1"
                     /translation="MRERSATGAQGLSKSIKKHLNDITRLTASLLGDEKLSAITSSSA
                     VKADIHRFVIELEPVKSTILQNDDISLDQNEIFEILKNFLDG"
     gene            complement(16159..16710)
                     /locus_tag="ACL3EZ_000871"
     CDS             complement(16159..16710)
                     /locus_tag="ACL3EZ_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001111259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0392469.1"
                     /translation="MPANTKVIFQEMFADFQNYYVLIGGTATSIVLDSQGFKSRTTKD
                     YDMVIIYEVKNKEFYTTLNHFLELGEYQGSQKDEKAQLFRFTTTNPEFPSMIELFSIL
                     PEYPLKKDGREIPLHFDQDASLSALLLDEDYYNILVHEKETIQGYSVLSNCGLYSSKI
                     SSNHVSFHLQPQNSVLSSLQLAS"
     gene            complement(16700..17695)
                     /locus_tag="ACL3EZ_000872"
     CDS             complement(16700..17695)
                     /locus_tag="ACL3EZ_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0392470.1"
                     /translation="MNVKKIMSIFQSFYVDVSIEELTLTLPISFVKRFEYTQMTFHKE
                     SFLLIKEKRRGSLSSFVTQARTMGEKANMDVVLVFSKLSDSEKKQLLQARVPFVDFKG
                     NLFFPPLGLVLNANDTEVPKELTPSEQLTWIAFLLTKGQKVVDVDLLSQVTGLPNSTI
                     YRCLRTFKALYWLNKQNKLYTYTVSKKELFLKSVSCLFNPIKKRILLPDGDIKQIKSV
                     SNLLYGGAYALSHSTFLAETDENTSYVIWQRKFNQLSLPLSQHVLKGKMLEIWKYRPF
                     VSEFWNDFKNNHDKQFVDPISLYLTLKDDDDPRIEEESEALENMILQYLGEDDAS"
     gene            complement(18103..18528)
                     /locus_tag="ACL3EZ_000873"
     CDS             complement(18103..18528)
                     /locus_tag="ACL3EZ_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000204059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0392471.1"
                     /translation="MTSRVFIDADCISVFLWVGTEHLLEKLYSGKIVIPQEVYDEINI
                     PTIPHLKSRIDQLVTKGSAEIVSIDIGTEEYALYRDLTRNHDSNKIIGKGEVASISLA
                     KKHNGILGSNNLRDVKPYVEEFSLEHMTTGDILIEAFKA"
     gene            complement(18672..19016)
                     /locus_tag="ACL3EZ_000874"
     CDS             complement(18672..19016)
                     /locus_tag="ACL3EZ_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HGR0392472.1"
                     /translation="MKKSSVSLILIGEGDETERKADQFASYFLIFPSSLYRMVEEIRE
                     NANRTHLEVEDIIKLGQFYGISHKVMLYRLRNDGYLDAEEIKNMDISVIETASRLGYD
                     TSLYRPLSESKK"
     gene            complement(19062..19268)
                     /locus_tag="ACL3EZ_000875"
     CDS             complement(19062..19268)
                     /locus_tag="ACL3EZ_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0392473.1"
                     /translation="MDLSNKASNLRKKLGADGESPIDIFKLVQKIENLTLVFYGLGKN
                     ISGVCYKGTQFSLIAVNSDMSLGR"
     gene            complement(19255..19416)
                     /locus_tag="ACL3EZ_000876"
     CDS             complement(19255..19416)
                     /locus_tag="ACL3EZ_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGR0392474.1"
                     /translation="MYVINVCDVGKRIKELRISSNLTQDKIAEYLSLNHSMIAKMEKG
                     ERNITNGFK"
     gene            complement(19774..20730)
                     /gene="lytA"
                     /locus_tag="ACL3EZ_000877"
     CDS             complement(19774..20730)
                     /gene="lytA"
                     /locus_tag="ACL3EZ_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase LytA"
                     /protein_id="HGR0392475.1"
                     /translation="MEINVSKLRTDLPQVGVQPYRQVHAHSTGNPHSTVQNEADYHWR
                     KDPELGFFSHIVGNGCIMQVGPVDNGAWDVGGGWNAETYAAVELIESHSTKEEFMTDY
                     RLYIELLRNLADEAGLPKTLDTGSLAGIKTHEYCTNNQPNNHSDHVDPYPYLAKWGIS
                     REQFKHDIENGLTIETGWQKNDTGYWYVHSDGSYPKDKFEKINGTWYYFDSSGYMLAD
                     RWRKHTDGNWYWFDNSGEMATGWKKIADKWYYFNEEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADKPEFTVEPDGLITVK"
     gene            complement(21106..22476)
                     /locus_tag="ACL3EZ_000878"
     CDS             complement(21106..22476)
                     /locus_tag="ACL3EZ_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009013566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HGR0392476.1"
                     /translation="MNKKRTVDLIHGPILLSLLSFAFPILLSNIFQQLYNTADVLIVG
                     RFLGQESLAAVGATTAIFDLIVGFTLGVGNGMGIVIARYYGARNFTKIKEAVAATWIL
                     GALLSILVMLLGFLGLYPLLQYLDTPAEILPQSYQYISMIVTCVGVSFAYNLFAGLLR
                     SIGDSLAALGFLIFSALVNVVLDLYFITQLHLGVQSAGLATIISQGLSAVLCFYYIRK
                     SVPELLPQFKHFKWDKSLYADLLEQGLAMGLMSSIVSIGSVILQSSVNTFGAVIISAQ
                     TAARRIMTFALLPMTAISASMTTFASQNLGAKRPDRIVQGLRIGSRLSISWAVFVCIF
                     LFFASPALVSFLASSTDGYLIENGSLYLQISSAFYPILSLLLIYRNCLQGLGQKILPL
                     VSSFIELIGKIVFVVLIIPWAGYKGVILCEPLIWVAMTVQLYFSLFRHPLIKEGKAIL
                     ATKVQF"
     gene            complement(22783..23949)
                     /gene="recA"
                     /locus_tag="ACL3EZ_000879"
     CDS             complement(22783..23949)
                     /gene="recA"
                     /locus_tag="ACL3EZ_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008094 - ATP-dependent activity, acting
                     on DNA [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HGR0392477.1"
                     /translation="MAKKPKKLEEISKKFGAEREKALNDALKLIEKDFGKGSIMRLGE
                     RAEQKVQVMSSGSLALDIALGSGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGI
                     AAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
                     ALVPRAEIDGDIGDSHVGLQARMMSQAMRKLGASINKTKTIAIFINQLREKVGVMFGN
                     PETTPGGRALKFYASVRLDVRGNTQIKGTGDQKETNVGKETKIKVVKNKVAPPFKEAV
                     VEIMYGEGISKTGELLKIASDLDIIKKAGAWYSYKDEKIGQGSENAKKYLAEHPEIFD
                     EIDKQVRSKFGLIDGEEVSEQDTENKKDEPKKEEAVNEEVTLDLGDELEIEIEE"
     gene            complement(24004..25260)
                     /locus_tag="ACL3EZ_000880"
     CDS             complement(24004..25260)
                     /locus_tag="ACL3EZ_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HGR0392478.1"
                     /translation="MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGD
                     NEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQTLAKFLGKALVFDPQAQEKLDIF
                     FTLRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPM
                     VLNQLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIDNQIDPTLAPYAKTGEVTLR
                     LSTKASSQEEANQALDILENQILDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQG
                     KTIAAAESLTAGLFQATVANFSGVSSIFEGGFVTYSLEEKSRMLDIPAKNLEEHGVVS
                     EFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGHPVGTVFIGLAQDQGTEVIKVNIG
                     GRSRADVRHIAVMHAFNLVRKALLSD"
     gene            complement(25344..26360)
                     /locus_tag="ACL3EZ_000881"
     CDS             complement(25344..26360)
                     /locus_tag="ACL3EZ_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0070726 - cell wall assembly [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HGR0392479.1"
                     /translation="MVKKIIGMVLALLSVTVVGVGVFAYTIYQQGTETLAKTYKKIGE
                     ETKVIEATEPLTILLMGVDTGNAERTETWVGRSDSMILMTVNPKTKKTTMMSLERDIL
                     TRIESGNGQAHEAKLNSAYADGGAELAIETIQKMMNIHIDRYVMVNMRGLQKLVDAVG
                     GITVNNILGFPISISDQEEFNTISIGVGEQHIGGEEALVYARMRYQDPEGDYGRQKRQ
                     REVIQKVMEKALSLNSVGHYQEILKALSDNMQTNIDLSAKSIPNLLGYKDSFKTIETQ
                     QLQGEGEILQGVSYQIVSRAHMLEMQNILRRSLGQEEVTQLETNAVLFEDLFGRAPVG
                     DEDN"
     gene            complement(26368..26886)
                     /locus_tag="ACL3EZ_000882"
     CDS             complement(26368..26886)
                     /locus_tag="ACL3EZ_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase family protein"
                     /protein_id="HGR0392480.1"
                     /translation="MEYELLIREAEPKDAAELVAFLNRVSLETDFTSLDGDGILLTSE
                     EMEIFLNKQASSDNQITLLAFLNGKIAGIVNITADQRKRVRHIGDLFIVIGKRYWNNG
                     LGSLLLEEATEWAQASGILRRLQLTVQTRNQAAVHLYQKHGFVIEGSQERGAYIEEGK
                     FIDVYLMGKLIG"
     gene            complement(26876..27319)
                     /gene="tsaE"
                     /locus_tag="ACL3EZ_000883"
     CDS             complement(26876..27319)
                     /gene="tsaE"
                     /locus_tag="ACL3EZ_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HGR0392481.1"
                     /translation="MYTKNEEELQALGERLGHLLAKNDVVILTGELGAGKTTFTKGLA
                     KGLQISQMIKSPTYTIVREYEGRLPLYHLDVYRIEGDADSIDLDEFIFGGGVTVIEWG
                     NLLGDALPDAYLELEILKEADGRRLNFQAKGLRAEKLLEELQYGV"
     gene            complement(27405..28025)
                     /locus_tag="ACL3EZ_000884"
     CDS             complement(27405..28025)
                     /locus_tag="ACL3EZ_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000839915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0392482.1"
                     /translation="MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFV
                     SGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLLINLLGAVLVLSDNLFIKNTLQQ
                     ELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
                     VSLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF"
     gene            complement(28408..29271)
                     /locus_tag="ACL3EZ_000885"
     CDS             complement(28408..29271)
                     /locus_tag="ACL3EZ_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGR0392483.1"
                     /translation="MSTLAEKFRLKRKELRLSQQTLAEGICEQSQISKIERGHFIPSA
                     DLLFKLSQRLEVPLDYFFNEQIEIKSNLSNFKQLSARLLDDRNYDDLEYIYRIEIERS
                     TFLTLEDRTYLEWIQAIIDFYQYDSKCEAISSLENILLKVSSNTLIYLKALNTLSNFY
                     SLVGREQEYEANYSHLIELYQTKNLDHQEFLFGYIRVRYNYAHYLVSKEKYNEAIQEA
                     LETIELCKQRQTSYQLAPLLILVGNAGAKFLDREQVKNYYIEARELCKIYNNPLMLMK
                     IENYLKELDTV"
     gene            29617..31632
                     /locus_tag="ACL3EZ_000886"
     CDS             29617..31632
                     /locus_tag="ACL3EZ_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HGR0392484.1"
                     /translation="MKKLFILISNLLASLFFVWVFTIWTDTYVSHYYPNVVVRDSSPE
                     TTFQHVATRLEKLAEETDSFIAIQHQDSNSEGTTVFSYTTFGDGKLPDGLQEKKLEDA
                     QSSSVETNYFVFDGHLDIHLLREELSQLGLTNMNLTIPSKLSTLMAIFSNGFQLISLL
                     IFILTFVALTLISQISQLRSSGIRLISGEKRWSIFLRPVGEDLKGIAVGFSLAGVLAI
                     LMQKILSLPTQSLMTIGAGLLSYNLILLSISLFFAQLFAVGIKKIHLMQIIKGQVPVR
                     GIISLILIGQLLAIIIITLGIGSSLKYSQAWQQHRIGQEAWSQERQLITLSISREGTS
                     PGFDEQAQRKLRTWYQLMDLAVSEQKAFLSRHQLIDRTLQNGMASSKNLITSTEWHDY
                     NPNGNVLIVTPQYLERQNIPVDTTIEQKMNHLNVGEFVLLLPEHLRSEEEHYKSVFED
                     DLTSRMSSQDERQQMTATVGYLESGQDRFVYNTTPISYQQFLKDPIIIVITPQSTGPQ
                     SILFWIDAVQNYVLFNQLSDAQELIQRQGIENWVSEMQTGYHNYITLLDNIQRERWVM
                     LAGAVLGIATSILLFNTMNRLYFEEFRRAIFIKRIAGLRFLEIHRTYLFAQLGVFLLG
                     FVASVFLQVEIGVAFLVLLLFTGLSLLQLHVQMQKENKMSILVLKGG"
     gene            31634..32266
                     /locus_tag="ACL3EZ_000887"
     CDS             31634..32266
                     /locus_tag="ACL3EZ_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0392485.1"
                     /translation="MIELKQVSKSFGERELFSNLSMTFEAGKVYALIGSSGSGKTTLM
                     NMIGKLEPYDGTIFYRGKDLANYKSSDFFRHELGYLFQNFGLIENQSIEENLKLGLIG
                     QKLSRSEQRLRQKQALEQVGLAYLDLDKRIFELSGGESQRVALAKIILKNPPFILADE
                     PTASIDPATSQLIMEILLSLRDDNRLIIIATHNPAIWEMADEVFTMDHLK"
     gene            complement(33195..33608)
                     /gene="ndk"
                     /locus_tag="ACL3EZ_000888"
     CDS             complement(33195..33608)
                     /gene="ndk"
                     /locus_tag="ACL3EZ_000888"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004550 - nucleoside diphosphate kinase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HGR0392486.1"
                     /translation="MEQTFFIIKPDGVKRGLVGEVLKRIEQRGFTIEKLEFRSQVSEE
                     LIDQHYQDLVGQSFYPPIREFMTSGPVLVGVISGPKVIETWRTMMGATRPEEALPGTI
                     RGDFAKAAGENEIIQNVVHGSDSEESAKREIALWF"
     gene            complement(33719..37396)
                     /gene="rpoC"
                     /locus_tag="ACL3EZ_000889"
     CDS             complement(33719..37396)
                     /gene="rpoC"
                     /locus_tag="ACL3EZ_000889"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HGR0392487.1"
                     /translation="MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPERE
                     GLFDEVIFGPTKDWECACGKYKRIRYRGIVCDRCGVEVTRTKVRRERMGHIELKAPVS
                     HIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEHKSIMTEREYRERLR
                     EYGYGSFVAKMGAEAIQDLLKQVDLEKEIAELKEELKTATGQKRVKAIRRLDVLDAFY
                     KSGNKPEWMILNILPVIPPDLRPMLQLDGGRFASSDLNDLYRRVINRNNRLARLLELN
                     APGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLG
                     KRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVARDIVQNVKAAKRLVE
                     RGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
                     FDGDQMAIHVPLSEEAQAEARILMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEEA
                     GREGEGMVFKDRDEAVMAYRNGYVHLHSRVGIATDSLNKPWTEEQRHKVLLTTVGKIL
                     FNDIMPEGLPYLQEPNNANLTEGVPAKYFLPLGGDIKEAISNLELNPPFKKKNLGNII
                     AEIFKRFRTTETSALLDRMKNLGYHHSTLAGLTVGIADIPVVDDKAEIIEESHKRVEQ
                     ITKQFRRGMITDDERYNAVTAEWRAAREKLEKRLIANQDPKNPIVMMMDSGARGNISN
                     FSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREDDCGTDRGLLIRSIAEGKEMIESLEERLNGRYTKKTVKHPE
                     TGAVIIGPNELITEDKAREIVNAGVEEVTIRSVFTCNTRHGVCRHCYGINLATGDAVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRVQEIFEARNPKGEAVI
                     TEVKGQVTAIEEDASTRTKKVFVKGETGEGEYVVPFTARMRVEVGGQVARGAALTEGS
                     IQPKRLLAVRDVLSVETYLLGEVQKVYRSQGVEIGDKHIEVMVRQMIRKVRVMDPGDT
                     DLLMGTLMDINDFTDANKDVLIAGGVPATGRPVLMGITKASLETNSFLSAASFQETTR
                     VLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNLEPHAVNEEEYLNPPVEEEG
                     NEETTEVVVDTAVETVEETVE"
     gene            complement(37429..41040)
                     /gene="rpoB"
                     /locus_tag="ACL3EZ_000890"
     CDS             complement(37429..41040)
                     /gene="rpoB"
                     /locus_tag="ACL3EZ_000890"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HGR0392488.1"
                     /translation="MAGHDVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFKAFLDHG
                     LKEVFEDVLPISNFTDTMELEFVGYEIKEPKYTLEEARIHDASYSAPIFVTFRLINKE
                     TGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
                     TVIPNRGAWLELESDSKDITYTRIDRTRKIPFTTLVRALGFSGDDEIFDIFGDSELVR
                     NTVEKDIHKNPMDSRTDEALKEIYERLRPGEPKTAESSRSLLVARFFDPRRYDLAAVG
                     RYKINKKLNVKTRLLNQTIAEPLVDPETGEILVEAGTIMTRSVIESIESHLDGDLNKI
                     VYIPNDAAVVTEPVVLQKFKVIAPTDPDRVVTIIGNANPDDKVRTVTPADILAEMSYF
                     LNLAEGLGRVDDIDHLGNRRIRAVGELLANQVRLGLSRMERNVRERMSVQDNEVLTPQ
                     QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVR
                     DVHYTHYGRMCPIETPEGPNIGLINNLSSYGHLNKYGFVQTPYRKVDRETGVVTNEIV
                     WLTADEEDEYTVAQANSRLNEDGTFAEKIVMGRHQGVNQEYPANIVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPYVGTGMEYQAAHDSGAAVIAQY
                     DGKVTYADADKVEVRREDGSLDVYHIQKFRRSNSGTAYNQRTLVKVGDVVEKGDFIAD
                     GPSMENGEMALGQNPIVAYMTWEGYNFEDAVIMSERLVKDDVYTSVHLEEYESETRDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERL
                     LHAIFGDKSREVRDTSLRVPHGADGVVRDVKIFTRVNGDELQSGVNMLVRVYIAQKRK
                     IKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHL
                     GMAARTLGIHIATPVFDGASSEDLWSTVKEAGMDSDAKTILYDGRTGEPFDNRVSVGV
                     MYMIKLHHMVDDKLHARSVGPYSTVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVL
                     QEILTYKSDDINGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDQ
                     EVELRDLDEGMDEDVIHVDDLEKAREKAAQEAKAAFEAEEAEKATKAEATEEAAEQE"
     gene            41456..41526
                     /locus_tag="ACL3EZ_000891"
     tRNA            41456..41526
                     /locus_tag="ACL3EZ_000891"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:41488..41490,aa:Cys,seq:gca)
     gene            complement(41724..43055)
                     /locus_tag="ACL3EZ_000892"
     CDS             complement(41724..43055)
                     /locus_tag="ACL3EZ_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin family protein"
                     /protein_id="HGR0392489.1"
                     /translation="MEDPSSQNLLLQFVLLFILTVLNAFFSATEMAMVSLNRARVEQK
                     AEEGDRRYIRLLKVLENPNHFLSTIQVGITLITILSGASLTDTLGRVIASWLGNGETA
                     QAVATFLSLAFLTYISIVFGELYPKRIALNLKDALAIRTAPIIIGIGKLVSPFVWLLA
                     ASTNFLSHLTPMSFDDADEKMTRDEIAYMLTNSEETLDADEIEMLQGVFSLDELMARE
                     VMVPRTDAFMVDIQDDSQAIIQSILKQNYSRIPVYDGDKDNVIGIIHTKSLLKAGFVD
                     GFDNIVWKRILQDPLFVPETIFVDDLLKELRNTQRQMAILLDEYGGMAGLVTLEDLLE
                     EIVGEIDDETDKAAIDVHQIGEDTYIVQGTMTLNDFNNYFDVELESDDVDTIAGYYLT
                     GVGTIPTTEKLSYELVSQNKQFILTNDKVKNGRVTKVKVQITEVEIEEETE"
     gene            complement(43346..44170)
                     /gene="endA"
                     /locus_tag="ACL3EZ_000893"
     CDS             complement(43346..44170)
                     /gene="endA"
                     /locus_tag="ACL3EZ_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-entry nuclease EndA"
                     /protein_id="HGR0392490.1"
                     /translation="MNKKTRQTLIGLLVLLFLSTGSYYIKQMQSAPNSPKTNLSQKKQ
                     ASEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIVNGNKTNLDAKVSSKPYADNKTK
                     TVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
                     LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRV
                     RYRVTLYYASNEDLVPSASQIEAKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ"
     gene            complement(44209..44397)
                     /locus_tag="ACL3EZ_000894"
     CDS             complement(44209..44397)
                     /locus_tag="ACL3EZ_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HGR0392491.1"
                     /translation="MNKKSSYVINRLLLVIIVLILGTLALGIGLMVGYGILGKGQDPW
                     AILSPAKWQELIHKFTGN"
     gene            complement(44390..45673)
                     /gene="murA"
                     /locus_tag="ACL3EZ_000895"
     CDS             complement(44390..45673)
                     /gene="murA"
                     /locus_tag="ACL3EZ_000895"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008760 - UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0019277 - UDP-N-acetylgalactosamine
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HGR0392492.1"
                     /translation="MDKIVVQGGDNRLVGSVTIEGAKNAVLPLLAATILASEGKTVLQ
                     NVPILSDVFIMNQVVGGLNAKVDFDEEAHLVKVDATGDITEEAPYKYVSKMRASIVVL
                     GPILARVGHAKVSMPGGCTIGSRPIDLHLKGLEAMGVKISQTAGYIEAKAERLHGAHI
                     YMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAILLNEMGAKVKGAGTETIT
                     ITGVEKLHGTTHNVVQDRIEAGTFMVAAAMTGGDVLIRDAVWEHNRPLIAKLLEMGVE
                     VIEEDEGIRVRSQLENLKAVHVKTLPHPGFPTDMQAQFTALMTVAKGESTMVETVFEN
                     RFQHLEEMRRMGLHSEIIRDTARIVGGQPLQGAEVLSTDLRASAALILTGLVAQGETV
                     VGKLVHLDRGYYGFHEKLAQLGAKIQRIEASDEDE"
     gene            complement(45697..45927)
                     /locus_tag="ACL3EZ_000896"
     CDS             complement(45697..45927)
                     /locus_tag="ACL3EZ_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014017351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 family protein"
                     /protein_id="HGR0392493.1"
                     /translation="MVQLLFTLSSHMLFIYVSFYLLKDLVRWEKVLKVTDDNTRKVRL
                     LVAFFSIVIGYILSSFFISLYHLWQEALRGLL"
     gene            complement(45985..47022)
                     /locus_tag="ACL3EZ_000897"
     CDS             complement(45985..47022)
                     /locus_tag="ACL3EZ_000897"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SepM family pheromone-processing serine
                     protease"
                     /protein_id="HGR0392494.1"
                     /translation="MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLK
                     VNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFTDIRSAQETTGGSSDVEFMRINQ
                     FYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
                     DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVIS
                     NVPISFSTAGIGGPSAGLMFSLAIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGID
                     KKVVASARAGAAIFFAPDNPVSEEEQKAHLDAKNNYQTALEAAKTIKTDMKIVPVKTL
                     QDAIDYLKNNP"
     gene            complement(47006..47494)
                     /gene="coaD"
                     /locus_tag="ACL3EZ_000898"
     CDS             complement(47006..47494)
                     /gene="coaD"
                     /locus_tag="ACL3EZ_000898"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004595 - pantetheine-phosphate
                     adenylyltransferase activity [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HGR0392495.1"
                     /translation="MSDKIGLFTGSFDPMTNGHLDIIERASRLFDKLYVGIFFNPHKQ
                     GFLPLENRKRGLEKALGHLENVEVVASHDELVVDVAKRLGATFLVRGLRNAADLQYEA
                     SFDYYNHQLSSDIETIYLHSRPEHLYISSSGVRELLKFGQDIACHVPESILEEIRNEK
                     KD"
     gene            complement(47484..48023)
                     /gene="rsmD"
                     /locus_tag="ACL3EZ_000899"
     CDS             complement(47484..48023)
                     /gene="rsmD"
                     /locus_tag="ACL3EZ_000899"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052913 - 16S rRNA
                     (guanine(966)-N(2))-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0031167 - rRNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HGR0392496.1"
                     /translation="MKIVSGIYGGRPLKTLEGKTTRPTSDKVRGAIFNMIGPYFEGGR
                     VLDLYAGSGGLSIEAVSRGMSSAVLVERDRKAQTIVAENIQMTKEVGKFQLLKMDAER
                     ALEQVSGEFDLVFLDPPYAKEQIVADIEKMAKRELFSEDVMVVCETDKAVELPEEIAC
                     LGIWKEKIYGISKVTVYVR"
     gene            complement(48088..49080)
                     /gene="asnA"
                     /locus_tag="ACL3EZ_000900"
     CDS             complement(48088..49080)
                     /gene="asnA"
                     /locus_tag="ACL3EZ_000900"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004071 - aspartate-ammonia ligase
                     activity [Evidence IEA];
                     GO_process: GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HGR0392497.1"
                     /translation="MKKSFIHQQEEISFVKNTFTQYLKDKLEVVEVQGPILSKVGDGM
                     QDNLSGVENPVSVKVLQIPDATYEVVHSLAKWKRHTLARFGFGEGEGLFVHMKALRPD
                     EDSLDATHSVYVDQWDWEKVIPNGKRNIVYLKETVEKIYKAIRLTELAVEARYDIESI
                     LPKQITFIHTEELVERYPDLTPKERENAICKEFGAVFLIGIGGELPDGKPHDGRAPDY
                     DDWTSESENGYKGLNGDILVWNESLGGAFELSSMGIRVYEETLRRQVEITGDEDRLEL
                     EWHKSLLNGLFPLTIGGGIGQSRMAMFLLRKRHIGEVQTSVWPQEVRDTYENIL"
     gene            complement(49192..49875)
                     /locus_tag="ACL3EZ_000901"
     CDS             complement(49192..49875)
                     /locus_tag="ACL3EZ_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1 family protein"
                     /protein_id="HGR0392498.1"
                     /translation="MNHTIIHDRAGLNQFYAKVYAFVGLGIGLSALVSGLMLTVFQSQ
                     LVYFLMQGRLWLTIATFAELALVFVASSMASRNSPAALPVFLLYSVLNGFTLSFVVAF
                     YTPGTVLSAFVSSALLFFVMAAVGIFTKKDLSGIGRAMMAALIGLLIAMVVNIFLASG
                     FFDYMISVAMVLVFSGLIAWDNQKIRLAYEQSQGRVATGWVVSMALSIYLDFINLFLS
                     ILRIFGRND"
     gene            complement(49931..50671)
                     /locus_tag="ACL3EZ_000902"
     CDS             complement(49931..50671)
                     /locus_tag="ACL3EZ_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0001510 - RNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrmH family RNA methyltransferase"
                     /protein_id="HGR0392499.1"
                     /translation="MTIITSKANSVVKNAKKLRQKKYRKSAYLIEGWHLFEEAVQAGV
                     TIEKIFALENYRDQLATFSQTVWVSEDILLDLADSQTPQGIVAVVQKEEVGQADLSQG
                     KFLFLEDVQDPGNVGTIIRTADAAGFTGVIVSDKSADIYSLKTLRSMQGSHFHLPIYR
                     MTSQALLDETKKVAIPVLATTLSKDSVDYRELPSIENFVLVMGNEGQGISPLMAESAD
                     QLVHISMKGQAESLNVAVAAGILIFHLS"
     gene            50705..50983
                     /locus_tag="ACL3EZ_000903"
     CDS             50705..50983
                     /locus_tag="ACL3EZ_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HGR0392500.1"
                     /translation="MQKVRMIAQGRVQGVGFRWGVYSLALEIGGITGRVWNNDDGTVE
                     ILAQADSSAIMAKFIQEIRKGPTPFSKVSYLDVKLSNFPPYSDFKIAN"
     gene            51061..51987
                     /gene="yidC"
                     /locus_tag="ACL3EZ_000904"
     CDS             51061..51987
                     /gene="yidC"
                     /locus_tag="ACL3EZ_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HGR0392501.1"
                     /translation="MKSIKRFALSAMGAAMLLVLTGCVNVDKTTGQPTGFIWNTIGAP
                     MAEAIKYFATDKGLGFGVAIIIVTIIVRLIILPLGIYQSWKATLHSEKMNALKHVLEP
                     HQTRLKEATTQEEKLEAQQALFAAQKEHGISMFGGVGCFPILLQMPFFSAIYFAAQHT
                     EGVAQASYLGIPLGSPSMILVACAGVLYYLQSLLSLHGVEDEMQREQIKKMIYMSPLM
                     IVVFSLFSPASVTLYWVVGGFMMILQQFIVNYIVRPKLRKKVREELAKNPPKASAFSK
                     PSGRKDVTPEQPTAITSKKKHKNRNAGKQRSR"
     gene            complement(52062..52856)
                     /gene="pflA"
                     /locus_tag="ACL3EZ_000905"
     CDS             complement(52062..52856)
                     /gene="pflA"
                     /locus_tag="ACL3EZ_000905"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043365 -
                     [formate-C-acetyltransferase]-activating enzyme activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate-lyase-activating protein"
                     /protein_id="HGR0392502.1"
                     /translation="MSEETIDYGQVTGMVHSTESFGSVDGPGIRFIVFLQGCHMRCQY
                     CHNPDTWAMESNKSRERTVDDVLTEALRYRGFWGNKGGITVSGGEALLQIDFLIALFT
                     KAKEQGIHCTLDTCALPFRNKPRYLEKFDKLMAVTDLVLLDIKEINEEQHKIVTRQTN
                     KNILACAQYLSDIGKPVWIRHVLVPGLTDRDDDLIELGKFVKTLKNVDKFEILPYHTM
                     GEFKWRELGIPYSLEGVKPPTADRVKNAKKLMDTESYQDYMKRVHG"
     gene            complement(52982..54232)
                     /locus_tag="ACL3EZ_000906"
     CDS             complement(52982..54232)
                     /locus_tag="ACL3EZ_000906"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000856498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008836 - diaminopimelate decarboxylase
                     activity [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HGR0392503.1"
                     /translation="MKTPFINREELEAIVAEFPTPFHLYDEKGIREKARAVNQAFSWN
                     KGFKEYFAVKATPTPAILKILQEEGCGVDCSSYVELLMSHKLDFLGSEIMFSSNNTPD
                     KEYAYARELGATINLDAFEDIEHLERVAGIPEIISCRYNPGGVFELGTDIMDNPGEAK
                     FGMTKDQLFEAFAILKEKGAKTFGIHSFLASNTVTHLYYPELARQLFELAVEIKEKLG
                     IWLDFINLSGGIGVNYRPDQEPNDIALIGEGVRKVYEEVLTSAGLGQVKIFTELGRFM
                     LAPHGALVTRVTHKKETYRTYLGVDASAVNLMRPAMYGAYHHISNVTHPDGPAEAVDV
                     VGSLCENNDKFAVNRELPHTEIGDLLVIHDTGAHGFSMGYQYNAKLRSAEILYTEEGK
                     ARQIRRAERPEDYFATLYGFDFEE"
     gene            complement(54299..55126)
                     /gene="purR"
                     /locus_tag="ACL3EZ_000907"
     CDS             complement(54299..55126)
                     /gene="purR"
                     /locus_tag="ACL3EZ_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004242125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA];
                     GO_process: GO:0045982 - negative regulation of purine
                     nucleobase metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HGR0392504.1"
                     /translation="MKLRRSDRMVVISNYLINNPYKLTSLNTFAEKYESAKSSISEDI
                     VIIKRAFEEIEIGHIQTVTGAGGGVIFTPSISSQDAKEMVEDLRTKLSESDRILPGGY
                     IYLSDLLSTPAILKNIGRIIAKSFMDQKIDAVMTVATKGVPLANAVANVLNVSFVIVR
                     RDLKITEGSTVSVNYVSGSSGDRIEKMFLSKRSLKAGSRVLIVDDFLKGGGTVNGMIS
                     LLREFDSELAGVAVFADNAQEEREKQFDYKSLLKVTNIDVKNQAIDVEVGNIFDEDK"
     gene            complement(55393..56334)
                     /locus_tag="ACL3EZ_000908"
     CDS             complement(55393..56334)
                     /locus_tag="ACL3EZ_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM family protein"
                     /protein_id="HGR0392505.1"
                     /translation="MKISHMKKDELFEGFYLIKSADLRQTRAGKNYLAFTFQDDSGEI
                     DGKLWDAQPHNIEAFTAGKVVHMKGRREVYNNTPQVNQITLRLPQAGEPNDPADFKVK
                     SPVDVKEIRDYMSQMIFKIENPVWQRIVRNLYTKYDKEFYSYPAAKTNHHAFETGLAY
                     HTATMVRLADAISEVYPQLNKSLLYAGIMLHDLAKVIELTGPDQTEYTVRGNLLGHIA
                     LIDSEITKTVMELGIDDTKEEVVLLRHVILSHHGLLEYGSPVRPRIMEAEIIHMIDNL
                     DASMMMMSTALALVDKGEMTNKIFAMDNRSFYKPDLD"
     gene            complement(56324..57580)
                     /gene="rmuC"
                     /locus_tag="ACL3EZ_000909"
     CDS             complement(56324..57580)
                     /gene="rmuC"
                     /locus_tag="ACL3EZ_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HGR0392506.1"
                     /translation="MESLLILLLIANLAGLFLIWQRQDRQEKHLSKSLEDQADHLSDQ
                     LDYRFDQARQASQLDQKDLEVVVSDRLQEVRIELHQGLTQVRQEMTDNLLQTRDKTDQ
                     RLQALQESNEQRLEQMRQTVEEKLEKTLQTRLQASFETVSKQLESVNRGLGEMQTVAR
                     DVGALNKVLSGTKTRGILGELQLGQIIEDIMTPAQYEREYATVENSSERVEYAIKLPG
                     QGDQEYVYLPIDSKFPLADYYRLEEAYETGDKDEIERCRKSLLASVKRFAKDIKSKYI
                     APPRTTNFGVLFVPTEGLYSEIVRNPVFFDDLRREEQIIVAGPSTLSALLNSLSVGFK
                     TLNIQKSADHISKTLASVKTEFGKFGGILVKAQKHLQHASGNIDELLNRRTIAIERTL
                     RHIELSEGEPALDLLHFQENEEEYED"
     gene            complement(57582..58244)
                     /locus_tag="ACL3EZ_000910"
     CDS             complement(57582..58244)
                     /locus_tag="ACL3EZ_000910"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000006147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004788 - thiamine diphosphokinase
                     activity [Evidence IEA];
                     GO_process: GO:0006772 - thiamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HGR0392507.1"
                     /translation="MSEYKLSENNWTRVAVFAGGDRGHYRTDFDAFVGVDRGSLWVLE
                     EDLLLALAVGDFDSVTEEERQVIQKRAQHFVQARPEKDDTDLELALLTIFEKNPQAQV
                     TIFGALGGRIDHMLANVFLPSNPKLAPYMHQIEIEDGQNLITYCPEGTSQLEPRSDYD
                     YLAFMPVRDSQLTILGAKYELTEENFFFKKVYASNEYIDREVSVTCPDGYVVVLHSKD
                     RR"
     gene            complement(58207..58863)
                     /gene="rpe"
                     /locus_tag="ACL3EZ_000911"
     CDS             complement(58207..58863)
                     /gene="rpe"
                     /locus_tag="ACL3EZ_000911"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004750 - D-ribulose-phosphate 3-epimerase
                     activity [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HGR0392508.1"
                     /translation="MSQYKIAPSILAADYANFEREIKRLEATGAEYAHIDIMDSHFVP
                     QISFGAGVVESLRPHSKMVFDCHLMVSNPEHHLEDFARAGADIISIHVEATPHIHGAL
                     QKIRSLGVKPSVVINPGTSVEAIKHVLHLVDQVLVMTVNPGFGGQAFLPETMDKVREL
                     VALREEKGLNFEIEVDGGIDDQTIAQAKEAGATVFVAGSYVFKGDVNERVQTLRKQLD
                     "
     gene            complement(58874..59752)
                     /gene="rsgA"
                     /locus_tag="ACL3EZ_000912"
     CDS             complement(58874..59752)
                     /gene="rsgA"
                     /locus_tag="ACL3EZ_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HGR0392509.1"
                     /translation="MQGQIIKALAGFYYVESDGQVYQTRARGNFRKKGHTPYVGDWVD
                     FSAEENSEGYILKIHERKNSLVRPPIVNIDQAVVIMSVKEPDFNSNLLDRFLVLLEHK
                     GIHPIVYISKMDLLEDRGELDFYQQTYGDIGYDFVTSKEELLSLLTGKVTVFMGQTGV
                     GKSTLLNKIAPDLNLETGEISDSLGRGRHTTRAVSFYNLNGGKIADTPGFSSLDYEVS
                     RAEDLNQAFPEIATVSRDCKFRTCTHTHEPSCAVKPAVEEGVIATFRFDNYLQFLSEI
                     ENRRETYKKVSKKIPK"
     gene            complement(59754..60626)
                     /gene="rsmA"
                     /locus_tag="ACL3EZ_000913"
     CDS             complement(59754..60626)
                     /gene="rsmA"
                     /locus_tag="ACL3EZ_000913"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000179 - rRNA
                     (adenine-N6,N6-)-dimethyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HGR0392510.1"
                     /translation="MRIADYSVTKAVLERHGFTFKKSFGQNFLTDTNILQKIVDTAEI
                     DDQVNVIEIGPGIGALTEFLAERAAQVMAFEIDHRLMPILADTLRDFDNVTVVNEDIL
                     KVDLAQHIQNFKNPNLPIKVVANLPYYITTPILMHLIESGIPFCEFVVMMQKEVADRI
                     SAQPNTKAYGSLSIAVQYYMTAKVAFIVPRTVFVPAPNVDSAILKMVRRPEPAVAVED
                     ENFFFKVSKASFTHRRKTLWNNLTGYFGKTEEVKDKLTKALDQAGLSPSVRGEALSLA
                     EFAGLADALKGQGL"
     gene            complement(60877..61170)
                     /locus_tag="ACL3EZ_000914"
     CDS             complement(60877..61170)
                     /locus_tag="ACL3EZ_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0392511.1"
                     /translation="MCEKIRIRRVSDYPSARGGLEDILIMENMTNHLLLVQIRVHGYL
                     LDFASIEGQRQKHYRLKNLPQTVELTVDDVEEDVDLTLPENRSYQEADFFDTQ"
     gene            complement(61163..61804)
                     /locus_tag="ACL3EZ_000915"
     CDS             complement(61163..61804)
                     /locus_tag="ACL3EZ_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0392512.1"
                     /translation="MIDIQGLEKKFNDRAIFSGLNLKLEKGKVYALIGKSGSGKTTLL
                     NILGKLEKIDGGRVLYQGKDLKTIPTREYFRDQMGYLFQNFGLLENQSIKENLDLGFV
                     GQKISKVERLERQVGALEKVNLGYLDLEQKIYTLSGGEAQRVALAKTILKNPPLILAD
                     EPTAALDPENSEEVMNLLVDLKDENRIIIIATHNPLVWNKADEIIDMRKLAHV"
     gene            complement(61806..63836)
                     /locus_tag="ACL3EZ_000916"
     CDS             complement(61806..63836)
                     /locus_tag="ACL3EZ_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000825281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HGR0392513.1"
                     /translation="MKRLFILISMVLVSLYMVITSVDHREEILFGNYPSVDVTGMMIN
                     QPVASREEVTEALSHLAVEHNSLIARRIVEPNEAGETLFTYATYGEGELPEGLTISSK
                     ESAETSDLLGSYLIVSGSLDGVSLQTTLKELGYQGFVSNGEDPFSIVLLLAATPMVLL
                     SLAIFLLTFMSLTLIYRIKSLRQAGIRLIAGESLFGVALRPVLEDVRQLICSVLVSSL
                     LGLGILWYQGALFMATVQLVIIALLLYGLTLAGISTLLSVVYLLGLQENSLVDLLKGK
                     LPLKRMMTLMMVGQLLAVLVVGSSATALLPHYREMQEMERASNKWSQSSDRYRLSFGW
                     SSAFADEEGTRKDNREWQTFTEERLANTDSFYIMSNVDNFSDGAEVDLDGNRLSDYTP
                     LGNVIYVSPRYLIEEKITVSSEFMDKMQNLSEGEFGLILPESLREQSAYYQGLFTDYL
                     QNFSSESVEVTSQKHYLPQVRLAFTETGQERFLYNDGYKTTRQYLKDPIIVVLTPQAT
                     GTRPVAGMLWGTTANSALKLDRYGDSITALKEQGLYHKVSYLVKSQLFFAKVLNDKRV
                     EFYSLLIGTILTLSTAILLFDSMNLLYFEQFRRELMIKRLAGMTIYELHGKYLLAQGG
                     VLLLGLVLSSILTRDGLISALVVALFTLNALLILVRQDKKEEAGSMAVLKGK"
     gene            complement(63913..64209)
                     /locus_tag="ACL3EZ_000917"
     CDS             complement(63913..64209)
                     /locus_tag="ACL3EZ_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000815395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HGR0392514.1"
                     /translation="MKQTVKKLALVASIAATLGGGVSVASAAVQYPEGGVWTYGSGNG
                     GAYSNYYHPSKYHSSTVVSRKTGSSDKGYAGAGGTSRAWIRTSWGEKVAFYYNV"
BASE COUNT        18831 a        14572 c        11899 g        19227 t
ORIGIN      
        1 aactttgaaa acttcaaaaa acggattttc atcgctctga atatcaaaaa agaaaggaca
       61 aaatttgtcc tttctcgagc ttagcttttc ttcaacccac tacagttgac aaagagccta
      121 taaaaagaag ggttagtcat tccctccttt tgtgtttttt ataagttgtt ttctatagaa
      181 agcttacatc atcccgccca tcatacttgg atccattgct ggagctgggg ctactggttc
      241 tggtttattg gctacgactg cttctgttgt caaaatcaag ctggctacag atgctgcatt
      301 ttgtagggct gaacgactca ctttaactgg atcaatgata ccttgatcaa tcatgttaac
      361 ccactcgcca gttgctgcgt tgaatcctat accaagctca gcatttttca aacgatcgat
      421 aacgatagat ccttcaaatc ctgcattgtg agcaatttga cgaacgggtt cttccaaagc
      481 acggagaaca atattacgtc ctgttgcttc atctcctgtc aattccaagg tagcaacagc
      541 tggaatcaca ttggcaagag ctgttccacc acctgcaaca ataccttctt caacagctgc
      601 acgagtagcg ttgagggcat cttcaatgcg gagtttcatt tctttcaact cagtttcagt
      661 tgcggctccg accttaataa ccgctacacc acctgacaat ttggccaagc gttcttgcaa
      721 tttttcacgg tcaaattcag aagttgtagt ttcgatttga gacttgataa ccgcaacacg
      781 gttagaaatc gcttcaggat ttcctgcacc ttctacaata accgtgctat ctttgtccac
      841 ggtcactctc gctgcttgac caagagcttc aattgtcgca tctttcaact caagaccaag
      901 gtcttctgtg ataactgttc cgcctgttaa gatggcgata tcttcaagca tggctttgcg
      961 acggtcacca aaaccaggtg ccttgactgc tactacgttg aaggttccac gaatcttgtt
     1021 caaaacaaga gttggaagag cctcgccatc cacatcatcc gcaataatca agagtggacg
     1081 attgctttgg agaatgcttt ccaaaagtgg caagatttct tggatattgg aaattttctt
     1141 gtctgtaatc aaaatgtacg gattttcaag gtcagccacc attttttcgc tatcagtcac
     1201 catgtactgt gaaaggtaac cacggtcaaa ctgcattcct tctacgactt caagctctgt
     1261 ttccatacca cgtgactctt cgatggtgat gacaccgtct ttgccaactt tttccattgc
     1321 ttcagagatg tactcaccaa ctttttcaga acgagaagat acggctgcaa cttgagcgat
     1381 agcttcttta ttggcaacag ggatggcgtt gtttttcaaa gcttcaactg ctgcggcaac
     1441 tgctgtttca atcccacgac gaataccgat tggatttgca cctgctgtga cgtttttgat
     1501 tccttcacgg acgatagctt gggtcaagac tgttgcagtc gtagtcccgt cacctgcgat
     1561 atcattggtt ttagaagcta cttctgatac taacttagca cccatatttt caaaatggtc
     1621 ttccaattcg atttctttgg caatggtcac accgtcattg gtaatcaagg gtgaaccgaa
     1681 tgacttttca agaacgacat tgcgaccttt tggtcccaag gttactttaa cagtgtctgc
     1741 aaggatatcg acaccacgaa ccatggctga acgggcatct gatgaaaatt taatttcttt
     1801 tgacatactt actttctcct tctattcctc aatgattgcc aaaatgttag cttcgcctac
     1861 gatgatgtac ttttcatcgc catctttgac atcaagacct gcgtgggctt caactaagac
     1921 acgatctcca gttttaacac ttggagcaac caagtcaccg ttcaaggtac gaacaccttg
     1981 tccagtagcc acaacttggg ctgttttggt tttttcttgg gctgaacctg cgagaacaaa
     2041 gcctccaaca gtttgttctt tttcttctac ttttaagacc acacggtccc ctaatggttt
     2101 caacatctga tttcctccat aatctgattt cctccataat gagatagata ttattagcac
     2161 tctttatacc tgagtgctaa ttcatagttc tattgtatca cttagtcaga aataatcaag
     2221 aaaaaagtct gactttctca agataaaaag cctgagacca actcagactt tttaattctt
     2281 aaaatggcaa ttcttcctct tccaagacca aatctgccaa atcttggcct gcattatttt
     2341 cacgcatagc acgttgggca cgactttcca agagttggaa tcctgtcaca aggacttcgg
     2401 ttacataatt catctgacca tttttctcaa agcgacgggt acgcaattct ccatcaacgg
     2461 aaatgagact acctttggtt gcgtagcttg ccaaagtttc tgctagtctg ccccatagaa
     2521 ccatattgac aaaatcagct tcacgttcac cgttttggtc tttgtaacga cggttgacag
     2581 cgatagttgc tcgcgctact gacttgtcat tgttggtttt gtgcaattct ggtgtagacg
     2641 ttaaacgtcc aatcaagata actttattat acatattttc ttcctcctac ttatctattc
     2701 gtaggaaatc aaaaaaagtt acagaaattt gtaacttttc gagaaaattt tttatttttt
     2761 atgaaccatg aaacctgtcg cctgttgatt ggccataatg gtcatatctg taatctgaac
     2821 acgacgaggt tgactagtca catagactac tgtatctgca atatcctgag cttgcaaagc
     2881 ttctattcct tggtaaacgg acgcagctcg ttctttatca ccatgaaaac gcactgtaga
     2941 aaaatctgtt tcgacaattc caggctgaat ggtcgtcacc ttgatatccg ttgcgatggt
     3001 atcaattcgc agtccatccg aaaaggtctt aaccgctgcc ttggtagctg agtaaacagc
     3061 ggcaccagca taggcgtaga ttcctgcggt tgaccccata tttataatat gaccttgatt
     3121 gacttttatc attgctggca agaaacagcg agtaaccgcc atcagacctt taacattggt
     3181 atccaacatg gtcaacatat ccaactcctc atagtcttga tagggagcca agtcaagagc
     3241 cagtccggcg ttgttgacca agatatcaat cctccctatc gtttctagaa tatcagagca
     3301 aacagtcttc accatgacca tatccgtcac atctagtgga aaagtccaga cggtttgatt
     3361 tggaaagctt actgcaaact ccgacttgag gatttctaat ctgtctatcc gtcgtcctgt
     3421 tagaacgaca tcctcaccct gctccaaata agcacgcgca atcgcttcac cgattcctga
     3481 ggttgctccc gtaatcacta cattttttgc catcttattt ccttctatca gatgctgaca
     3541 agttcctagg cagtccagtg tttcgctggg tcgaacggtg ttccgacaac ttggtcttct
     3601 gataattcaa gcaccccacg tttttgcgga gcatttggca aatgcaattc acgaggacta
     3661 cacatcatcc caaaactctt ttcaccacga agttcgcctg ggaaaatgaa attccctttt
     3721 ggcatcatgg caccaggaag agccacaatg gttttcaacc caacacgcgc attaggtgct
     3781 cctgcaacga tttgcactat cttgtcactt gcgactgcaa cttggcagat gttgaggtgg
     3841 tcactgtctg gatgagctac catctcgaca atttcaccaa caacaaactt aggttcctta
     3901 tcattaacaa tttcttctgt aaaaccttcc gcctgtaatt cttggttcaa acgagcgact
     3961 tgctcatctg ataaaaagac ttgaccgcgc tctgcaattt caaacaagct cgaaacctca
     4021 aaaatgttcc aagctactgt ttccccattt tcttttttga ggaaaacacg ggctaccttg
     4081 cctttgcgtt ccacattcag tttggcatct ccgctatttt tcacgatgac cataaggaca
     4141 tcaccgacat gttctttgtt atacgtaaaa atcattgttt cctttttctc ctatttcaat
     4201 cctgctaaaa aatcgttaat ttgctcctta cttttacggt cgcgattgac aaaacgaccg
     4261 atttccttgt ccttttctag aacaacaagg ctaggaattc cgtaaacatc ccagagtttg
     4321 gccaaatcca tatactgatc tcggtccatt cgaataaagg tgaactctgg attggtctcc
     4381 tcaatctctg gtaaggcagg ataaatataa cgacaatcgc cacaccagtc tgccacaaaa
     4441 aggaagacct tcttgcccgc tttttccact aaagatgcta attcttctaa acttgctggc
     4501 tgtatcataa gacttcctcc tcatagacta ggtcttcatt ttcatagaca aaggtataat
     4561 gacggccatc ctcaaaaatg acgccaccaa ccaagctctc cagactgctt tcgtaaactt
     4621 gaacatagag ggtcgcaatt tcccccatgt cggaaaaatg gtctcgcaca atctctgtca
     4681 actcttcctg agtcttcatg agcttacggt catctgcaac ttttttcgtg gcaagagcaa
     4741 ggcttccgat acctagcaga gccaagcctg ccatccacat ttttttagct ttcataccat
     4801 tcattttaac acaaaaaagg cttcaggaca aatgaggaag cagcagaaaa gcaagtaaaa
     4861 agcctcttcc tttaaggaaa aggacttctt atactaagac caaactagaa agctagccgc
     4921 aggctgctca aaacacggtt ttgaggttgt agataaggcg acgctgacgt ggtttgaaga
     4981 gattttcaaa gagtattatt cttattgcca ggcacctaag ttgccaacgt agtaaccatc
     5041 aggtgtgtag gtattgcgaa acatcttacc tgatgaagcc agataatact acttgccatt
     5101 gtctttgacc caatcattcg caatcatgga accagaagaa cttacataat accattctcc
     5161 cttgtcataa acccaagtac tgactttcat ggttcctgag caattaaagg caaaaaaact
     5221 gtccaatatc attcgttttt taaaagcatt tgacactaca tcatctacgc tgtagtacat
     5281 agatacatca aacgtaaaag ccaaaatatc gaaaaatata caatttttaa aggcagcatt
     5341 tcatttttta aagtctaaca accatagaac tgaaatcaga gcaaggcatc aatttcctac
     5401 tcttagtacg tctattttga tggttgaagt gaagattttt ttatttaacg tagacaattt
     5461 ccaacttccc aaaagccaca tctccacgga tagtcaaggt tttgctggtt ggggctacag
     5521 gagcgtcagc cttagctgca ccaaaggagg tttctacttt caaatctaca cgccagtgtt
     5581 gtggaacata gacggttgca tttccgaagg ccacttcaat atttaaagtt gcaaaatcac
     5641 ctagcatctc tgcattatca tagtagattt tagcatcccc aaaagcgact tccacttggt
     5701 catctacgag atcttgatct tgcttataga aggtcccgct accaaaagcg acttccttag
     5761 ccgtgacgac tgtttttttc ccattgtacc accatttttt ttcattccag aacttacttg
     5821 aatgcgtcag ataaccaaca ccaagtacca ccaagatgct agcccaaata agagaatgat
     5881 tggtaactgg taacaagtca taagcgtaat ttgcaatgat gagcgccagt aaacctgtaa
     5941 aaactgccga agtgagatga cgtctaagga tggactcaat ggacttataa gcaaaaaaaa
     6001 caatacctag taaaggccat attttaccat ccaaagaagg aattccaaaa ttcccttgca
     6061 gcaagatcca agctgctaaa accaataaaa caataccaaa tgctttcttt ttcatgtttt
     6121 ttacctcatg tttcttagat tttcttttag gagggattgg taatgccgtg agacatgaac
     6181 ctccttgtgc gtctgataaa aggaaatggt gcccgttcct gaaaaggact tgtccactga
     6241 gtaaatctga cggatgtttg cgatcgttga cttggaaact cgattaaaat agcgaggcaa
     6301 gatagactcc aactcataga gcttgaggcg aacctcataa gcttccttct ggttatgagc
     6361 gtagatcttg ctcccttctg tttcaaagaa gagaatttct gacaggtcta gataatattc
     6421 acctgtcccc ttgtaaaaag tcaacctcgg agcctttgac tcttgcaaga gccgttgcaa
     6481 gtctgcaatt tcatctgtca aagtgggggt cttgatgaca atttcagtct cctctaaatt
     6541 gccgtcaatc tcaattcgta acttcatcac atctcctttc tgactctact atatcaaagc
     6601 taagttagga atacaagggc aaaaaagcaa gtggtcaatt tgaagcagta agtggttgta
     6661 ggactagctt aacttacatg tcagaatagg aagaaaagga atccccacac caaaccacaa
     6721 gcatagccaa ccaagacatc cttgggataa tgaacacccc ctaaaaccct caccaacccc
     6781 agcaaagctg aaaagatcaa gcatactaag ccaataggta gactagcatg cagacaggcc
     6841 acggagatga tagttgccga aaagacatgg cgactgggca tcgaccgtcc cgaactatcc
     6901 ttatcaagaa ggggacagat atcccaagtt tcataaggtc tcgggtgatt gattttctta
     6961 cgaaacaggg acaaggccac aaaacctgat gcaggaataa gcacataaac cccaacttgc
     7021 tgaccaagtc ctagttgcag gtaagtggtg actagcaaga tcagatagac caggggcatg
     7081 gcgactgtca tcaaacgatt gaaactgcgt aataggaata aaagaattgg acgactagtt
     7141 agtctggagc tgatatttcg ataccattct tgataatttt tcatttatgc ttctcatact
     7201 tttctagaac ttgttgagat gttttcccct tggcaagcca atccactagc ttgtccaagc
     7261 gacgtatttc ctgcatcaga ggatcatcaa tttcctcaat acggacaccg caaatcttcc
     7321 ctgtaattgc aattcgttca gggacataat atggtgcttg tctaaaaaaa tctccgtaag
     7381 taacatccct atccagacaa gcaagaacat cactcacttc ataccctgtc aaccaactgg
     7441 tcacttgatg aactgactct gcctttccac cctttcgctc aacttttgca atcaaggcta
     7501 agtagacagc agcaaatttc atattgtata atttctgact catacttctc tctttctatg
     7561 tgtactagta taaataagaa aaagaaggcc gtcaagcctt cttttgattt attcttctgc
     7621 ttcatcttct gtaaattgac tattgtacaa gtcagcgtag aagccacctt gcgccatcag
     7681 ttcctcatag ttgccttgct cgatgatatt tccatctttc atgaccaaga tcaagtctgc
     7741 atttcggatg gttgacaagc ggtgggcaat gacaaagaat gtgcgtcctt ccatcaaacg
     7801 gtccatggct ttttggatca attcctctgt ccgtgtgtca acagaagaag tcgcctcatc
     7861 caaaatcaaa agcggtgcat ccttaagaag ggcacgagca atagtcaata gttgtttttg
     7921 tcctacagac aaggtcacgg tgtcatccaa gatggtatca tagccatctg gcaaggtcat
     7981 aataaagtgg tgaattccca cagccttact agcttccatc attcgttcat cactaatccc
     8041 tatttgatta tagatgagat tgtctcgaat agttccttca aagagccagg tatcctgcaa
     8101 gaccattgaa aaggcatcat gcacttctga acgcgtcata gccttggtat ccacaccatc
     8161 aatgtgaata cttcccttat caatctcata gaatttcatc aaaagattga caatggttgt
     8221 cttaccagtc ccagtcggcc caacaatggc aaccttttga ccagcatgag ctgtcgcaga
     8281 gaagtcatag tcttgaacat tgacaccgtc caccagaatt tctcctgctg acacgtcgta
     8341 gaaacgtgga atcagattga ccagagttga tttaccagaa cctgttgacc caataaaggc
     8401 cactgtttga ccagtttctg ctttaaagct aacatgttca ataactgcct ccgaatttgc
     8461 cgcatagcgg aaggtcacat ccttaaactc gacctgacct ttgaagtttt catcagtcag
     8521 ctgcacttga acagggtttt ggatagaaga atgcaaatat aaaacttgat taatccgctt
     8581 agcagagacc atagttcggg gaagaacgat gaagagtgct cccatgagaa ggaagcccat
     8641 gacaacctac atggcataag acatgaaaac aatcatgtca ctaaagagag gcagacgcgc
     8701 tatcggagca gcgtcgttaa tcacataggc cccaatccag taaatcgcca cactcaaacc
     8761 acttgaaatc cccatcatga taggattcaa aatagccata agacggttga caaacaaatt
     8821 caaacgggtc aattcatcat ttactgctgc aaatttttca ttttgataat cctctgcatt
     8881 gtaggcacga acgacacgaa tacctgttaa actctcacga gtgatactgt tcagtttatc
     8941 tgtcagcccc tgaatcaagg actgttttgg aaaggctagc gtcatcaaaa cggtcgtcat
     9001 caggacgttg acaatcactg ccacaagtac ggcccagagc cagtattctg aatgacctaa
     9061 aatcttccca atagcccaga tagccataat tggaccacac gttaccactt gcaagcccat
     9121 agtaatcaac atttgaactt gagtaatgtc attggtagta cgcgtcaaga ggctaggaat
     9181 tgaaaatttc ttaatctctg tctgcgagta atccaaaact cggttaaaaa tatcacttct
     9241 cagcctacta gtataagaag ccgccactcg ggatgcaaaa aatccaactg caactacgga
     9301 caagaaggca agaaagagca ttcccatcat catgcttgcc ggctgccaca actcatctaa
     9361 attagttcct tgactaccta gcaaatccgt aattttcgag atataggtcg gcacttccaa
     9421 ctctagatag accgaaaagc aagtaaagag aatggctagt aaaatcatcc ccattctttt
     9481 ctactaattc ttttggctaa tttctttatt ctctcctcct attcccttga tatttgcctg
     9541 tagttgaccg agaactttct caaaaatcag taattcatct tcatcaatgt cttccatcaa
     9601 ctgcttgtct atgcgttcaa aaaaagcctt aacctgttgc atctgagaac gtgctttgtc
     9661 cgtcagacga acaaacttag cccgcttatc aacaggactc gcctccaatt ccaccaaacc
     9721 attttgcact atacgcttaa ccagattact agcaacagac ttggtaatat tgagttcctg
     9781 ctcgatatct ttaatcaaga ccaagtcttg gtttttctcg cgattatcca aaaaacgcac
     9841 aacctgacct tgcggcccac ccataaattc aatgccgcaa cgtttggctt ccttttgcac
     9901 catcaggtga atttgatgac caaaacgctt aaagactaac atcggtttac ccataatctc
     9961 ccccttctaa ataaaaatag ttctctggag aataattaaa tttctatgag aactattttc
    10021 ttgattaaaa aaatcccaag tgattttctc acttaggatc atgttctata ggttaaatta
    10081 aaacccatct acgttcgtat aaatcttttg gacgtcttcg tcgtcttcaa gaacgctgta
    10141 aagtttttca aaggtttcaa ggtcttcgcc tgacaattcc acttctgact gaggaatcat
    10201 ttccaattca gtcacttgga attcttcaat accagactca cggagggcaa cgatagcctt
    10261 gtgaaggtca gttggcgctg tgtaaactgt gattgtacct tcttgtgctt ctacgtcatc
    10321 cacatccaca tccgcttcga gcaattgctc aaagactgcg tccgcatctt cacctccaaa
    10381 tacaataaca cctttgttgt caaagaggta agaaacagaa cctgaagcgc ccatgtttcc
    10441 gccgttttta ccaaaggctg cacggacatt ggctgctgta cggttgacgt tagaagtcaa
    10501 agtatccaca attagcatag agccatttgg cccaaaacct tcgtaacgtc cttctgtaaa
    10561 ggtttcgtct gtgtttcctt tggctttatc aatcgcttta tcgataatgt gttttggcac
    10621 ttgggcttgt ttagcacggt cgataacgaa tttcaaagct gagtttgatt ctggatctgg
    10681 atcacctttt ttagctgcta catagatttc tacaccaaat tttgcatata ctttagagtt
    10741 ggctccatct ttagccgttt tcttggctac gatattggcc catttacgtc ccattaggaa
    10801 tctccttttt tcacatttta atctttctta ttataacaca agtttttttg attttcacta
    10861 gaggaaatgg attttattag caaatcaagc taggatagca ctttacctgc taagatggtc
    10921 ttgcctttct atctttttat caacagacac tcatccacat tcaaaaaaca aactagacca
    10981 ttatctgcaa atagaaagtt tcagccaagt ttgacaaagt cagctcaaat tactgtttga
    11041 agtttgtaga tataagcgac aaaaacaatc atactgcacc ttttgttgac agtctactcc
    11101 agacatatca tagttcaagt aaatactttg aaatccaaca gttcttatag gcgctattgt
    11161 attctaagaa atcaatagaa gagtttctaa gcaaatctct aatactcaat aaaaatcaaa
    11221 gagcaaacta gaaagctagc ctcaggttgc tcaaaacact gttttgaggt tgcggatagg
    11281 gctgacatgg tttgaagaga ttttcgaaga gtataattta cgtgttccca agatggagaa
    11341 gttagactag tacactggca cttctaaacc attgctagca attgatttgt tcatatttaa
    11401 tttcattttt tccataaatg ggtattagat ataaacagca aaatatttcc gatacgtgtc
    11461 gttcttgaat ttccaatcat ctaaaacaag taaaggataa tcaatcccct gtatatcaag
    11521 gaattggcta ccctttttac ttttttacac attctgtttg atagattcat tttaacatca
    11581 cgagcatact ccaatggaaa tcgctaggca agagataaac tttcagatat ccgcagagag
    11641 atcatcgcct ctttttgtcg caagcattct cctctcctag tcattttcta ccttatcttc
    11701 tacctgcgga tagagagttg ttccccaaat agaaatcgtc cgcttacgca ctagtggcaa
    11761 atcggttttt tcataaaccg tacgccacca ttcccaagca agcccggtac actctctaat
    11821 tttgacagag agattacgaa cattcccttt taaaggaata ctagtggtaa agtgagccgt
    11881 taaatcctgc ccatttctgt cccaagcctt aggagtcaag acttccttac cttgatgatc
    11941 ataggataat tcattccaag taatataata ttgggcaaca taggcaccac tatgatccag
    12001 cagtaaatct ccgtttctgt aagctgtaac cttagtctca acatagtctg tactattttg
    12061 aaaggtcgca actacattgt cacgtaaaaa agaagttgta taggaaatcg gcaagcctgg
    12121 atgatctgct gtaaagcgac tgccttcttg aatcaagtcc tctaccatat ccaccttgcc
    12181 tgttacaact cgggcacccg aacttgggtc gccccctaaa ataaccgcct tcacttctgt
    12241 attgtccaaa atctgcttcc actctgtctg aggagctacc ttgactcctt ttatcaaagc
    12301 ttcaaaagca gcctctactt catcactctt actcgtggtt tccaacttga gatagacttg
    12361 gcgcccataa gcaacactcg aaatatagac caaaggacgc tctgcagaaa ttcctctctg
    12421 ttttaaatcc tctaccgtta cagtatcttg aaacacatct cctggatttt taacagcgtc
    12481 tacgctgact gtataataaa tctgcttaaa attaacaatc tgaatctgct tttcgcctga
    12541 atggacagag ttaaaatcaa tatcaagaga attccctgtc ttttcaaagt cagaaccaaa
    12601 cttgaccttg agttgttcca tgctgtgagc cgtgattttt tcatactgca ttctagctgg
    12661 gacattattg acctgaccat aatcttgatg ccacttagcc aacaaatcgt ttaccgctcc
    12721 gcgaacactt gaattgctgg ggtcttccac ttggagaaag ctatcgctac ttgccaaacc
    12781 aggcaaatca atactataag tcatcggagc acgatcgacc gcaagaagag tgggattatt
    12841 ctctaacaag gtctcatcca ctacgagaag tgctccagga tagaggcgac tgtcgttggt
    12901 agctgttaca gaaatatcac ttgtatttgt cgacaagctc cgcttctttc tttcgataac
    12961 aacaaactca tcgggtagct gattaccctc tttgatgaaa cgattttcaa tactttctcc
    13021 ctgatgggtc aagagtttct ttttatcgta attcatagct agtataaagt catttactgc
    13081 tttatttgcc atcttctacc tcctaataag ttcctggatt gagttgcata aactcagact
    13141 tgttcagcga aatcagccgt ggttggacta agtaatccaa aatttcctcg tacaattctt
    13201 ctgagacatt gcgtcgccgt ctggctagat aagaagtcgg aataaccgta ttatccaaca
    13261 taaatacctt atctaagtca atcaaggttg gtcttgtaaa aggattacga gctagatccg
    13321 gctcttctat cataaagttc ttgaccaaac gtctggtcaa gagagctggt ttgaaggtct
    13381 gatttttaac caactctttg tttttagtca tgctgttgtc aatacagata tacatatgat
    13441 tcttcacagc caaatcgcta ctaatagtcg gaaaaggcaa ataaagagct acaacatctc
    13501 ctctcttaat caagcaagag cacccccttt tctcctaatg taacatagac aggattgacc
    13561 aagtcttctg attgactcag aatttccaaa gtttgagttt ggcgcgctgt caatttagta
    13621 gcatcttgtc tcttcaatac aaaatgcttg tcgccaataa ccttgacaat ataatccttc
    13681 tccaaagctg actggtaaat ccacatcaga tgttgtctgt cctgagaact caagagagaa
    13741 ggattttcaa gcctcccgat agtctgataa aaatcaaaaa caggagctaa ctcctgccaa
    13801 tctgattggc tagttgtcaa ggctagaaaa agggctttgc gagctgatac ttcttggtta
    13861 gccttgagag ttactttccc ctccaagttt tttagaaatc gggaaactcc agaaagcaaa
    13921 tttttctcta actgcgagaa ataaaaacct ttcgttccca gacataagtc tttcatgtcg
    13981 ctttctctag caaataagag ctcaaacatt tgatagtaaa agaaaaatat ctggcactgg
    14041 gtcgcgctca tcttttcctt atcggcttct ttttttaacc agagcaaggg cgacaggtag
    14101 ctggattgag acatttcctc tacctcctac tcttttttaa ctggagcatc tgcactagct
    14161 gccacttctt ttgactggat actttcccac tggttaatct cctctgagat aagaccttcg
    14221 catgtcttga caaatagggc aaaagccttg gtctttcctg catatttctc cgtttggcat
    14281 tgatagagga atttttcttt ctccaggagt tgcgcagttt tttggtaaga aatccaattt
    14341 tcctttgcat tatacaaatt gataatcccc tcacacagca agccgagact ggataaggca
    14401 accgaaatca aacggtagcg atcacctggc ataggaatag cacaaaagac agctatgagg
    14461 aaacctgcca cgatttctgt tatttttaat accttatagc gcctacgatg ttgaacgctt
    14521 ttctttaaaa aatgagctat ctgtacgtct aatcgctctg tcaggtacat ttcttctggc
    14581 gtcatattcg taactccttt catttacttt gataatcata gtataacata tttgaatatc
    14641 aaagtatagt aaaaactgga ctataactta ttagacttcc tacgaaacaa aatatggtat
    14701 agtagttcta tgaatgatga agcaagtaaa caactaactg atgcacgatt taagctcctt
    14761 gttggtgttc agcgtaccac ttttgaagag atgttagctg tattaaaaac agcttatcaa
    14821 aaaagtcgga caagctggta aaatcttggc tgacagtggt tatcaagggc ccatgaagat
    14881 atatcctcaa gcacaaactc cacgtaaatc cagcaaactc aagtcgctaa tagctgaaga
    14941 taaagcctat aaccatgcgc tatctaagga gagaagcaag gttgagaaca tctttgccaa
    15001 agtagaaacg tttaaaatgt tttcaacaac ctatcgaaat catcgtaaac gcttcggatt
    15061 acgaatgaat ttgattgctg gtattatcaa tcatgaacta ggattttggt ttcgcaggaa
    15121 gtctattata tatgcacaga catatgaaat ctttttgaga tagcagttat gatatattta
    15181 tccattcaca acatcttctg tactaatact acaatattgg tacattttga ttacacaatc
    15241 gtttcaaaaa atatgatgga agcctgagta ttttatagta attcccttcc tatcaactag
    15301 atcaaccagt tgagtgttga atgttgaaac accctagcct cagcaaagga ctatgatcag
    15361 catttcctag ccaataggac gctccaaatc acctattcta agtccatcac tagcttggtc
    15421 agtaagatac agactgcaag gcgagactga cgtggttgat gagattttgg aagagtatta
    15481 caatcataga ttcaccagta gacttgaccg cagatttaac tatagtatat tgaaactaga
    15541 atagtacacc tctacttcta aaacattgtt agaaatcgat ttgactgtcc tgatcaattt
    15601 gtcctgttct tttttcattt cactatacta aaaaaccacc tgaaacaaat caagtgacta
    15661 gaggataaaa acaaagactg ggcaaaaagt tttgaaaagc aaaaaacgca taatatcagg
    15721 tcttgaaaaa ccttgacgtt tgattgtggg aagattgact tcattttctc ctgaaattga
    15781 agttttttct agtttccaga tatagacgaa ttcaatatag ccatctcgct acaattattt
    15841 taaccatcga gaaaattttt cagaatttca aaaatttcat tttgatccaa tgaaatgtca
    15901 tcattttgaa gaatagttga cttcacaggc tctaattcta tcacaaagcg gtgtatgtct
    15961 gcttttaccg cactacttga tgttatagcc gataactttt catctcctag caaggaagct
    16021 gtcaaacggg taatgtcatt caaatgcttt ttaatggact tacttaaacc ttgagcacct
    16081 gtagcagagc gttccctcat atccagccaa gctttagcct taaaaataat taatactcaa
    16141 tgaaaatcaa agagcaaact aggaagctag ctgcaggctg ctcaaaacac tgttttgagg
    16201 ttgtagatgg aagctgacgt ggtttgaaga gattttcgaa gagtataaac cacaattact
    16261 caataccgaa tacccctgaa tggtttcttt ttcatgcacc aatatattat aataatcttc
    16321 atccaataat aaggctgata aactagcatc ttggtcaaaa tgtaagggaa tttctcgacc
    16381 gtccttcttt aatggatatt ctggtaagat actaaatagt tcaatcatag aaggaaactc
    16441 aggattagtt gttgtaaatc gaaaaagctg cgctttctca tctttctgac ttccttgata
    16501 ctctcccaat tctaaaaaat gattcaaggt agtataaaat tccttatttt ttacttcata
    16561 aatgatgacc atatcataat cttttgttgt gcgactttta aatccttgcg aatccaatac
    16621 gatagaggta gcagttcccc caatcagaac ataatagttc tgaaaatccg caaacatttc
    16681 ttgaaaaata actttcgtat tagctggcat catcttctcc cagatactgt aatatcatat
    16741 tttctagtgc ttcactctct tcctctatac gtgggtcatc atcatctttt aaggtcaaat
    16801 aaagagaaat cggatctaca aattgtttat catgattatt tttaaaatca ttccaaaact
    16861 cagatacaaa aggacgatat ttccatatct ctagcatctt tccttttaaa acatgctgag
    16921 aaagtggcaa ggataactga ttgaattttc tctgccatat gacatagcta gtattttcat
    16981 ccgtttcagc taaaaaagtt gaatgcgaca aagcataagc accaccatat agaaggttag
    17041 aaacagattt tatctgcttt atatcgccat ctggcaataa aatccgtttt ttgatgggat
    17101 taaataaaca tgacacggat tttaagaata attctttctt tgacaccgta tatgtgtaaa
    17161 gcttattttg cttgtttaac caatataaag ctttaaaagt cctcaaacac ctataaattg
    17221 ttgagtttgg aagtccagtg acttgtgaaa gcaaatcaac atctactact ttttgacctt
    17281 ttgtcaataa aaaggcaatc cacgttaatt gttcgctagg tgttaattcc ttagggactt
    17341 cagtatcatt cgcattcagt actagtccca atggagggaa gaagaggttt cccttaaagt
    17401 ctacaaacgg aactctagct tgaagtaatt gctttttttc actgtctgat aacttcgaaa
    17461 acaccaaaac aacatccata ttggcttttt cacccatagt gcgagcctga gtaacaaatg
    17521 aactcaaact cccccttctc ttttctttaa tcaataaaaa tgattcctta tgaaaagtca
    17581 tttgagtata ctcaaacctt tttacaaaac tgattggtaa agtcaaagtc agttcctcaa
    17641 tactgacatc aacataaaag gattgaaaaa ttgacattat ctttttgaca ttcatgtttt
    17701 ttccttattc tatcattttt attatatttt atcattcggt ataataaaat ataagttttt
    17761 tgataaaata accaaaaact actcgctatc ccctctcaca ttaccctaca tatcgtttga
    17821 catgcgactg atagttcagg aaaacttcaa ggagaacttt tctctcatcc actatgcagg
    17881 acttactatt tcacttctac tcctataggc tcaatttgac acttttcttt ttcgaattgc
    17941 tcatatgcct cctgaatagt gagttcgatt tatccaaatt tatttttgtc tattttgatg
    18001 aatacttcca cgaagatagt ctgaaaatga atttgcacca attttccttc tctttttaag
    18061 catattattc cagatatgat tgccctcttg ttcagtaata aattacgctt taaacgcttc
    18121 aatcagtata tctcctgttg tcatatgttc taaagaaaat tcttctacat atggtttaac
    18181 atctcttagg ttattacttc ctaatatccc attatgcttt ttcgctaagg aaatagaagc
    18241 cacttctccc ttaccaataa tcttgttact atcatgattt cttgttaaat ctctatataa
    18301 tgcgtattct tcagttccaa tgtctatgct cacaatctca gctgaaccct tagttaccaa
    18361 ctggtctatc ctagatttta aatggggaat tgtaggtata ttgatttcat catacacctc
    18421 ttgtggaata acaattttac ccgaatagag cttttctaaa agatgttcag taccaaccca
    18481 taaaaatact gaaatacaat ctgcatcaat aaatacacga ctagtcaaac gacaactccc
    18541 ccctcttcat ctagcccata tacaatatca tatctgaaag catctagtaa cagttcctca
    18601 tacttccctt gcgaaattct gttattttct aaaagttgtt cagttgaatt aacatattat
    18661 cctaatatca tttacttttt actttctgac aaaggacgat ataaacttgt atcatagcct
    18721 aatcttgaag ctgtctctat aacactaata tccatatttt taatttcttc tgcatcaagg
    18781 tatccatcat tcctcaatct atataacata actttatgac tgataccata aaactgaccc
    18841 aattttataa tatcttctac ttcaagatga gttctattgg cattttctct aatttcctca
    18901 accatcctat acagtgaaga tgggaaaatt aaaaaataag aagcaaactg atccgctttt
    18961 ctttcagttt catctccttc accaatcaag ataagactga ctgaactctt cttcacctca
    19021 tcataataaa gatgatacag ttcatgtgct aaagaaaatc tttaccttcc taatgacatg
    19081 tctgaattga ctgcaatgag actgaactga gttcctttat aacagactcc gctaatattc
    19141 tttccgagtc cataaaatac cagcgtcaaa ttttctatct tttgtaccaa tttaaaaata
    19201 tctatcggcg attcaccatc agctcccaac ttttttctaa gatttgaagc tttattactt
    19261 aaatccattc gtgatattcc tttcaccttt ttccattttg gcaatcatgc tgtgattcaa
    19321 agacaaatac tcagcaatct tatcttgagt aagatttgaa gatattctaa gttcttttat
    19381 tctttttcca acatcacata catttatcac atacatttat catattcata cacctctcat
    19441 aaaaagaata gcacactctt gtcataattt tttaaataaa aaaattatga caaaacaagg
    19501 aagcaattta ttgatgctgc ttaaaaatct aaaattgatg agttcctatc aaaaatcgta
    19561 tcttcaacct caaaacagta cttaaagcta tccgactcgg tttacattgt caaatttaga
    19621 ttttatttga gcataacttt ctagtttgct ttttgatttt tgtttaatat agtagcaaaa
    19681 ttgaaggaaa tatctccaca agaaagcgca tactattaag ctttttcaag acctaataat
    19741 atgcgctgtt ctgatttgaa agacattcca ttattatttt actgtaatca agccatctgg
    19801 ctctactgtg aattctggct tgtctgccag tgttccgtct ggtttgaggt agtaccagcc
    19861 tgttccgtcc gctgactgga taaaggcatt tgataccatg gcgccttctt tagcgtctaa
    19921 gtagtaccaa gtgtccttgt acttgaccca gcctgtcttc atggcacctt cttcgttgaa
    19981 atagtaccac ttatcagcga ttttcttcca gcctgtagcc atttcgcctg agttgtcgaa
    20041 ccagtaccag ttgccgtctg tgtgcttcct ccagcggtct gcaagcatat agcctgaact
    20101 gtcaaagtag taccaagtgc cattgatttt ctcaaacttg tcttttggat aagagccgtc
    20161 tgaatgtacg taccagtagc cagtgtcatt cttctgccag cctgtttcaa tcgtcaagcc
    20221 gttctcaata tcatgcttaa actgctcacg gctaatgccc catttagcaa gatatggata
    20281 agggtcaacg tggtctgagt ggttgtttgg ttggttattc gtgcaatact cgtgcgtttt
    20341 aattccagct aaactccctg tatcaagcgt tttcggcaaa cctgcttcat ctgctagatt
    20401 gcgtaagagt tcgatataaa ggcggtagtc cgtcatgaac tcttctttgg ttgaatggct
    20461 ttcaatcagt tcaaccgctg cataggtctc agcattccaa ccgcccccaa cgtcccaggc
    20521 accattatca acaggtccta cctgcatgat gcaaccgttc ccaacaatgt gcgagaaaaa
    20581 acctaattct gggtctttcc gccagtgata atccgcttca ttctgtacgg ttgaatgcgg
    20641 attcccagtt gagtgtgcgt gtacttgcct atatggttgc acgccgactt gaggcaaatc
    20701 tgttcttaat ttactcacat taatttccat attctactcc ttatcaatta aaacaactca
    20761 ttttttacaa tccagaacca gaaactcctt tatttctacc ttacaaagaa gacaatctta
    20821 gtcacgatta ggcttgtaga tagaacttca aaacgcacta ttttgacact gtaaatagga
    20881 ctgacaaggt ctgcattcta tctacaataa caccccagac taaaaagctt ttcaaaagta
    20941 tatttttaca gtctctatat gtccttttca taaatactat actttattat atcatataaa
    21001 agaagtcaaa agtctgttaa actattttca acaccaaact aaagaagaga acacaagttt
    21061 tttcgatttt cactagagga aatggatttt attcagtaaa tccaactaga attgcacttt
    21121 ggttgccaaa attgcctttc cttcttttat caagggatga cggaatagtg agaagtacag
    21181 ttgaactgtc atggcaaccc agataagagg ttcacaaagg ataacaccct tatatcctgc
    21241 ccaaggaata atcaaaacca caaaaacgat ttttccgatt agttcaataa agctagaaac
    21301 tagaggaagg atcttctgcc ccaagccctg caagcaattg cgataaatca acaagaggct
    21361 caaaatggga taaaaggctg aactgatttg cagatagaga cttccatttt ctatcaagta
    21421 accatctgtc gaactagcca agaaggaaac caaggctgga ctggcaaaaa agaggaaaat
    21481 acaaacaaaa actgcccagg atatacttaa acgactgccg attcgaagac cttgaacaat
    21541 gcggtcaggt cgcttagctc ctagattctg agaagcaaag gtcgtcattg atgcagaaat
    21601 agcggtcata ggaagaaggg caaaggtcat aatgcgtcga gctgccgtct gggcactaat
    21661 aatcactgca ccaaatgtat taacagaaga ctgtaaaatc acactgccga tagatacaat
    21721 tgaactcatc aagcccatag ccaaaccctg ctccaagaga tccgcgtaca agcttttgtc
    21781 ccatttgaaa tgtttaaact gtggcaagag ttctggcaca cttttacgaa tataataaaa
    21841 gcagagaacc gctgataaac cttgcgaaat aatggtagca agtcctgcgg attgaactcc
    21901 cagatgcaat tgcgtaataa aatagagatc cagaaccaca ttaaccaagg cagagaaaat
    21961 cagaaatccc agggctgcta gactgtcacc aatagaccgc aacaagcctg caaaaagatt
    22021 ataagcaaag ctgacaccta cacaggtcac aatcatagaa atatattgat aagattgagg
    22081 aagaatttct gcaggagtat ctaagtattg caagagagga tacaagccaa gaaagcccag
    22141 caacataact agaatgctca aaagagcacc taaaatccag gtggctgcta ctgcttcctt
    22201 gattttagtg aaattccgag ccccataata acgagcaatg acaatcccca tgccattgcc
    22261 aacaccaagt gtaaaaccta caatcaggtc aaaaatcgct gtcgtcgctc ctactgcagc
    22321 caaggattct tgaccaagaa atcgtccaac aatcaagaca tcagcagtgt tatagagctg
    22381 ttgaaaaata tttgatagca agattgggaa ggcgaagctt aagagcgaga gaagaatcgg
    22441 accatgtatc aggtccactg ttcgtttttt attcataaag ctattatatc agctttccag
    22501 aggagcgaca agaaacagca aacttatata tagcggaatg aaataaggac agtcaaatcg
    22561 atttttaaca atgttttaga agtagatgtg tactattcta gtttcgatct attatagttg
    22621 gttgagtttg gaatagtacg ctgtagctgc taaaacattt ctagaaatta atttgacttt
    22681 cctaataaag ttgttcatat cttatttcaa gctactatat ataatctaaa aacttgaatc
    22741 aaaaatcgaa aaagtagcgg atttctccac tgctttaaca gcttattctt caatttcgat
    22801 ttcaagttca tcgcctaagt caagcgtaac ttcttcattc actgcttctt ctttctttgg
    22861 ctcatctttt ttgttttcag tatcttgttc tgaaacttct tctccatcaa tcaagccaaa
    22921 tttagaacgg acttgcttat caatttcatc aaagatttct gggtgctctg ccaagtattt
    22981 cttagcattc tcagaacctt gcccaatttt ttcatctttg taagaatacc aagcccctgc
    23041 ttttttgata atatccaaat cgcttgcaat cttcaaaagc tcaccagtct tagaaattcc
    23101 ttctccgtac ataatttcaa ctacggcttc cttaaacggt ggagctacct tattttttac
    23161 aaccttaatc ttagtttctt taccgacatt ggtttctttt tgatcaccag ttcccttaat
    23221 ttgtgtatta ccacgaacat ccaagcggac tgaagcatag aatttcaaag cacgtccgcc
    23281 cggtgttgtt tctggatttc caaacatcac tccaactttt tcacgcaatt ggttgataaa
    23341 aatggcaatt gttttggttt tattgataga ggcgccaagt ttacgcatgg cctggctcat
    23401 catacgagcc tgcaaaccaa catggctatc tccgatatct ccatcaattt ccgcacgagg
    23461 aacaagggca gcaactgagt cgactacgac aagatcaact gcacctgagt caatcaattt
    23521 tcccgcaatt tcaagacctt gctctcctga gtctggttga gacaagagca attcgtcaat
    23581 attgacacca agggccgcag cataagctgg atcaagggca tgttccgcat cgataaaggc
    23641 agcaatccca ccttcttttt gcgcttgtgc aactgcatga agggcaaccg ttgtcttacc
    23701 agatgactct gggccataga tttcgatgat acgtccctta ggataaccac ctgagccaag
    23761 ggcaatgtca agagctaaag aacctgagct catcacttgc accttttgct ccgcacgttc
    23821 acccaaacgc atgattgatc ctttaccaaa gtctttctca atcaatttaa gagcgtcatt
    23881 caaggccttt tcacgttctg ccccaaattt ttttgaaatt tcttctaatt tttttggttt
    23941 tttcgccatt ctattctcct acattctaat gatcctcaga cctatctact attatatcaa
    24001 aagttagtca cttaataaag ccttgcgaac taggttaaag gcatgcataa ccgcaatgtg
    24061 acgtacatct gctcggcttc tgcctccaat attaaccttg ataacctcag ttccttgatc
    24121 ttgcgccaag cctatgaaga ctgtcccaac tgggtgtcct tctaggctat ctggtcctgc
    24181 cactccagtc aaactaattc caaaatcaga ctgggtcttg cttcgtgcct gctcagccat
    24241 cttctgagct gtaaattcag acaccacacc atgttcttcc aaattcttgg caggaatatc
    24301 caacatcctt gatttttcct ccaagctata ggtcacaaaa ccaccctcaa atatacttga
    24361 aactccagaa aaattcgcca cggtagcttg gaaaagacct gccgtcaaac tctctgcagc
    24421 cgcgatggtt ttcccttgcc ttttcagttc ttctaccaca atgctggcta aactagtttc
    24481 ttccccataa ccatagcaaa agtctcgtaa agaaattcct tcgaaagtct ggcagtccaa
    24541 gatttgattt tccaagatat ccagcgcttg attcgcctct tcttgactgc tagcctttgt
    24601 tgacagacgt agagtgactt ctcctgtctt ggcataaggg gccaaggtag gatcgatctg
    24661 attatcaatt aaatcagcca aaatcgtaac caactggctc tcgccaatcc caaagaaacg
    24721 aagaactcgg gaatacagct tgctccctgt catcaacttg ggtagaagtt ggtttaagac
    24781 catgggtttc aattcacttg gcggacctgg aaggacgaca taggtcactc cgtctacttc
    24841 taattttcct ccaacagcca gtcctgtttc gtttggcagt ggaatcgctc cttctacaat
    24901 ttgagcttgt ctttcgttat ttggtgttcg ggcatagtct ggtcgcaggg taaaaaagat
    24961 atccaacttc tcctgagcct gaggatcaaa gactaatgct ttccctaaaa atttagctag
    25021 ggtttgtttg gttaggtcgt cctcagttgg ccccaaaccg cctgtcaaaa tcaccagact
    25081 gctacgttga ctggcaatct caagcaaaga caagagacga acttcattgt ctcctacagc
    25141 cgtctgaaaa tatacatcta ccccaatctc agctagtttt tccgacaaaa actgggcatt
    25201 ggtgttgaca atctgtcctg tcaaaatctc tgttccaaca gcaatgattt ctgctttcat
    25261 gtttcctcct acctatctat tcgtattttt ttgaaaaaat cgcaggaatt ttcctacgat
    25321 tgatttttta tttgtatcaa aagttaatta tcttcatcac caacaggtgc tctgccaaat
    25381 aaatcttcaa ataaaaccgc attggtttca agctgagtaa cttcttcttg tcccaaagaa
    25441 cgtcggagta tattttgcat ttccaacata tgtgctctcg aaacaatctg gtaagaaaca
    25501 ccttgaagta tctctccttc accctgcaac tgctgagttt caatggtttt aaatgaatct
    25561 ttatagccta gcaagttagg gatacttttt gcagacaaat caatattggt ctgcatattg
    25621 tcactcaaag cttttagaat ctcttgataa tgaccaacgc tatttaaact gagagctttt
    25681 tccatgactt tttgaataac ttcacgttga cgtttttgac gaccataatc cccctcagga
    25741 tcttggtaac gcattcgtgc atagactagg gcttcttctc ccccaatatg ttgctcccca
    25801 acaccgatag aaatagtatt aaattcttct tggtcactga tagaaattgg gaaacctagg
    25861 atattattga ctgtaatacc tcctactgca tccactagtt tttgcaaccc tctcatattg
    25921 accatcacat agcgatcaat atggatattc atcatttttt gaatggtttc tatagcaagc
    25981 tctgctccac catctgcata tgctgagttc agtttcgctt catgagcctg accattccct
    26041 gattcaatgc gcgtcagaat atcccgctct aaactcatca ttgttgtttt tttcgtttta
    26101 ggattcactg tcatcaagat catgctatca cttctaccga cccaagtttc agttcgttca
    26161 gcatttccgg tgtccactcc cattaacaga atggttagag gttcagtcgc ttcaataacc
    26221 ttggtttctt cgccgatttt tttataggtt ttagctaagg tttctgtccc ttgttgataa
    26281 atagtataag caaaaacacc tactcctact acagttacag aaagtaaagc tagcaccatt
    26341 ccaataattt ttttaaccat atttctacta acctatcagt ttacccatca agtaaacatc
    26401 gataaatttc ccttcttcta tatatgcccc acgctcttgg ctaccttcaa tgacaaagcc
    26461 atgcttttga taaagatgga ctgctgcttg attacgagtt tggacagtca gttggagacg
    26521 acgcagaatg ccacttgctt gtgcccactc tgtcgcttct tctagcaaca aacttcccaa
    26581 gccattattc caatatcttt ttccaatcac aatgaagaga tctccaatat gacggactct
    26641 cttacgctga tcagctgtaa tatttacaat accagcaatt ttgccattta agaatgcaag
    26701 taaggttatc tgattgtccg aactagcttg cttgttgagg aatatttcca tctcctcact
    26761 agtcaagaga ataccatctc cgtctaggct ggtaaagtct gtctccaaac tcacacgatt
    26821 taaaaaggcc actaattcag ctgcatcttt gggctctgct tccctaatga gcaattcata
    26881 ctccatattg aagctcctct aacaatttct cagcacgcaa accctttgcc tgaaaattta
    26941 aacggcgtcc atctgcttct tttagaattt ccaattctaa ataagcatct ggcaaggcat
    27001 ctcctaagag atttccccac tcaataacag tcacgccgcc accaaagata aactcatcca
    27061 agtcgataga atcagcatct ccttcaatac gataaacatc taggtgataa agtggaagtc
    27121 gaccttcata ctctctcacg atagtatagg tgggactttt aatcatttga gaaatctgta
    27181 atccttttgc aagtccttta gtaaaggtcg ttttacctgc acccagttct ccagttaaga
    27241 ttacaacatc attctttgct aatagatggc ccaaacgctc ccctaaggct tgcaactctt
    27301 cttcattttt tgtgtacata ctcttattat accaaaaact tttcttttgt gtctattttc
    27361 ctactaaact tatcatcata acatccataa aaaacagact ttctctaaaa gaaaatgagc
    27421 gtaacaatga ccaatacaag atctcggaaa atatgaccat aaaaggaaac ttccttctta
    27481 accgaatttg ggacaagata ggctgcaaaa aacaagccca gtccaatata aatcagaagt
    27541 gagacaatgg tcattggatt tcttaagaaa agaagtgttg ctaaaatagt caccaacact
    27601 gtcttttttc tgtctagcat agcaagaaaa tcgcgcacgt attttttcaa gggtaaaaaa
    27661 atcagcaaat ctagcccaaa taggaaaaag aaggatggca ataaaaagtc aactaattct
    27721 tgctgcagcg tatttttgat gaacaagtta tctgacaaaa caagaacagc tcctaacaaa
    27781 ttaattaaga gtaacatact gtaaaaaagc ttcaccgact tcttactggc taggacacta
    27841 tggacttctt gcttacgggt ataaagataa tttactccag cacagattcc tgaaacgaaa
    27901 accatgcttc cgatgaaaaa agctgtactt tgtttaaagg acaagatgca ttccttccat
    27961 aagaaacagc tactcaaact gatttgaatt aaagctaaca aaaataagat tctcattgat
    28021 ttcatcttct ctctcccttc ctaccaatca ttatactagg agaaaagaga gaactgtttc
    28081 taatcttctc aaatgtctct ttaagacgct aaacaaacac tagagactaa tactcaatga
    28141 aaatcaaaga tcaaactagg tagctagcca caggttgctc aaaacactgt tttgagattg
    28201 cagatagagc tgacgtgatt tgaagagatt ttcgaagaat ataaatttga aatcatgaaa
    28261 atccgtcaaa cgggtggttg ttttgtctcg cacctcacgg agcgagacgg actcagagtc
    28321 acataattat aaggctgata gtattaatct aactatcagc cttacaggtt atttaacgtt
    28381 tcagaaaaac tataatgtca agattaacta aacagtatct agttccttca aataattttc
    28441 tatcttcatc aacattaaag gattgttata aatcttacat aactctcttg cttctatata
    28501 ataatttttg acttgttctc tgtctagaaa tttggctcca gcatttccta caagaataag
    28561 tagaggagcc aattggtagc ttgtctgtct ttgtttacag agttcaatcg tttcaagagc
    28621 ttcttggatg gcttcattat atttttcctt tgatactagg tagtgagcgt agttgtaacg
    28681 aactctgatg tagccaaata aaaactcttg atggtccaaa ttttttgtct gatacaactc
    28741 tattaaatga gagtagtttg cctcatattc ttgttcacga cccactaagg aatagaaatt
    28801 agatagagta ttcaacgcct ttaaataaat cagagtattt gaagagactt ttaataatat
    28861 attttccaat gaagaaattg cctcacactt actgtcatat tgatagaagt caataatagc
    28921 ttgaatccat tcaaggtaag ttcggtcttc tagtgttaga aaagtacttc gttcaatctc
    28981 tattctataa atatattcca aatcgtcata atttctatcg tctaatagtc gagcagacaa
    29041 ttgcttgaaa ttagagaggt tagatttaat ttcaatttgt tcattaaaaa aataatctaa
    29101 tggtacttca agtcgttgag agagtttgaa caaaaggtct gcggagggaa tgaaatgccc
    29161 tctctcaatt ttactaatct ggctttgttc acaaattcct tctgcaagag tttgttggga
    29221 gagtctcaac tcttttcttt tcaatctgaa tttctctgcg agtgtactca ttaaagataa
    29281 taaaccttcc tatttgctta attgcattat aaaattttta gttcaaaata gcaagttaaa
    29341 gaaataaata attctttatg gtaataaact aaaaaaagtc aaaaattaca taaaaatgct
    29401 tgaccgaata atatatatat attaaaataa aaacaaggaa aaagaaaggg gtttcattgc
    29461 atgagaaaaa aacgtggaat taaaaaatta gttacatttg atgcgggatg gtaaagaata
    29521 attgaagaag attcttttat caatagttta gtaagcttgt tagtttatag agggcagggg
    29581 tatttctgcc ctctgtttta gaataaggaa tgcactatga aaaaattatt tatactcata
    29641 tccaacctgc ttgctagttt gttctttgtt tgggtattta ccatttggac tgatacatat
    29701 gtctcccatt attaccccaa cgttgttgta cgtgattctt cccctgaaac aacttttcag
    29761 catgttgcta cacgcttgga aaaactagca gaagaaacag atagctttat tgcgattcaa
    29821 caccaagatt ctaactcaga aggtactaca gttttttctt atacgacctt tggggacgga
    29881 aagttgcctg atgggcttca ggaaaaaaaa ctagaagatg ctcaaagtag tagtgttgaa
    29941 acaaactatt ttgtattcga tggacaccta gatattcact tgctaaggga ggagctaagt
    30001 caacttggct tgactaacat gaacctgaca attccatcta aactatctac gttaatggct
    30061 atctttagta acggatttca gttaatcagt ctattgattt tcatcttaac ctttgtagca
    30121 ctgactttaa ttagtcaaat tagccaatta cggtcgtcgg gcattcgcct catttcagga
    30181 gagaaacggt ggtccatttt ccttagacca gttggtgagg atttgaaagg gatagctgtt
    30241 ggtttcagtt tagctggcgt gctcgccatt cttatgcaaa aaattctgtc gcttccaacg
    30301 caatccctaa tgaccatagg agcaggcttg ctcagttata atctcatctt gttgtcgatc
    30361 tccctgtttt tcgctcaact cttcgcagtt gggataaaaa agatacacct gatgcagatt
    30421 ataaaagggc aagtgcctgt cagaggaatc attagtttga ttttaatcgg tcaactatta
    30481 gcgattatta ttataacgct gggaataggg agtagcttaa agtattccca agcctggcaa
    30541 cagcatcgga ttggacaaga ggcttggagt caggaaaggc aactgattac cctatcaatc
    30601 agccgtgaag gaacgagtcc tggttttgat gaacaagctc aaaggaaact cagaacttgg
    30661 tatcaattga tggatctggc tgtttcagaa caaaaggctt tcttatctag acaccagtta
    30721 attgaccgta ctttgcaaaa tggcatggct tcctccaaaa acttgataac ctctacagaa
    30781 tggcacgatt acaacccgaa tggcaatgtc cttatcgtca caccgcaata cttggagcgt
    30841 caaaacattc ctgtagatac aactattgag caaaagatga atcaccttaa tgtaggggag
    30901 tttgtcttat tgctgcctga acacctccgt tcagaggaag aacattataa atctgttttt
    30961 gaagacgact taaccagtcg catgtctagt caagatgaac gacagcaaat gactgctacg
    31021 gtaggttatt tagaatcagg tcaggatcgt tttgtgtata atacgacccc tatttcttac
    31081 cagcagtttt tgaaagatcc aatcatcatt gttataacac cccaatcaac tggtccacag
    31141 tccattttgt tttggataga cgcagtacag aactacgttc tctttaatca attgtctgat
    31201 gcccaggagc ttatccagag acaaggcatt gaaaattggg tctcagaaat gcaaacaggt
    31261 taccacaact acatcacatt attggataat atccagaggg aacgttgggt aatgctagca
    31321 ggagctgtgc ttgggattgc aacttcaatc ttgttgttta acactatgaa taggctctac
    31381 tttgaagaat ttagacgtgc catttttatc aaacgcattg caggtctcag gttcttagaa
    31441 atccatcgca cttatctctt tgctcaactg ggtgtgtttt tactgggatt tgttgcgagt
    31501 gtatttcttc aggtagagat aggagttgct ttcttagtct tgttactctt tactggtcta
    31561 tctcttttac agttacatgt ccaaatgcag aaagaaaaca agatgtccat tcttgttttg
    31621 aagggaggtt aatatgattg aacttaaaca ggtgagtaaa tcttttggag aacgagagtt
    31681 attttcgaat ctttcaatga catttgaggc tggaaaagtc tatgccttaa ttggttcaag
    31741 tggtagcgga aaaacaacct tgatgaacat gattgggaaa ttagaacctt atgatgggac
    31801 gattttttac cgaggtaaag acttggccaa ttataaatcg agtgattttt tccgtcacga
    31861 attgggctac ctcttccaga actttggctt aattgaaaac caaagtattg aagaaaacct
    31921 taagctaggt ctcattggtc aaaagttgag tcggtcggaa cagcggttga ggcagaagca
    31981 ggctttagaa caggtcggcc tggcttatct tgacctagat aagcgcatct ttgagttatc
    32041 gggcggagaa tcgcaacggg ttgccttggc aaaaattatc ttaaagaatc caccctttat
    32101 tctggcagat gagccaacag cttcaataga cccagcaacc tctcagttga ttatggagat
    32161 tttgctatct cttcgagatg ataataggct aatcattatc gcaacacata atccggcaat
    32221 ttgggagatg gctgatgaag tgttcacgat ggatcatctg aaataaaaat ccttgttttt
    32281 aattgcacga tgagttactg aaatattatc atgaatcaag aattggagtt aatttagaat
    32341 tgtactttat taatattgag gtaacttttt cttgataaag gaagaaataa tggagaggaa
    32401 gttagaatga aaaaattcga caattatatt attgagaagc cttgcgattc taattcagat
    32461 aaactgcaaa aaatcttaat aattgaaagt ttggtagatg atattttgca attttctctc
    32521 agaatcaata atagtgtagg agagattttc ctcctacaac cgttttaaaa gaaaactatc
    32581 tttattccat gttattttga ggaagatatt gtgaaagtca aagatgatga taaagttgag
    32641 tggaatttgt tagaatttca aaaatttaga gcatttttgg cttagtaatc tgtgttgaag
    32701 gctcaaaacc tatggtaaaa aagtagcttt gaaaacgtat tgcctccaaa gatttagtta
    32761 aataatgatt taacacaaaa agaaattatt gaagttctgg aaagatgttg tttcagtatt
    32821 gagaaaaggt gggaaaaact tgcgattttc acagagaaag gaagaaaaag tatagaaata
    32881 tagtcaattg aaacaagaac aggataaaag aaccttttgt gccatatttt tctcctttcg
    32941 ctttacaatt ggattgaaca cctttattgt atcgcgtttg gagttttttt ggtataacct
    33001 tcgacgcgca cccgcatagc gggtgttttt tttgtctcgc acctaacgga gcgagacaaa
    33061 ctaatagtca cttaatcaaa aaacgcacca tatcaaaaac taaaaagttt gatatcatgc
    33121 gtcatgtctt aaactaattg actatacttt ctattcaaat gagcttttaa ccaattgatt
    33181 gagccaatcc actcttaaaa ccaaagagca atttctcgct tagctgactc ttctgaatct
    33241 gaaccatgta caacattttg gataatctca ttttctccag cagcttttgc aaaatcacct
    33301 cgaatagtgc ctggtaaagc ttcttctgga cgagttgcac ccatcatggt ccgccaagtt
    33361 tcgattactt tgggaccaga aatgacaccc acaagaactg gacctgaagt catgaattca
    33421 cgaatcggtg ggtaaaaact ctgaccaacc aagtcctgat agtgctggtc aatcaactct
    33481 tctgaaacct gtgaacgaaa ctccaatttt tcgattgtaa atccacgttg ttcgatgcgc
    33541 tttaacactt cacccactag ccctcttttt acaccatctg gtttgatgat aaagaatgtt
    33601 tgttccatac ccgtctcctt tgtcagcttc tttcttttat tttaccacat ttcgtggaaa
    33661 aatggagaaa gttttcagaa gagagaatga gagaacccga gggttctctc attctctctt
    33721 attctactgt ttcttccaca gtttcaacgg cagtatccac aactacttct gttgtttctt
    33781 catttccttc ttcctctact ggaggattaa ggtattcttc ttcgttgaca gcatgtggtt
    33841 caaggttacg gtaacgggcc ataccagtac cagctgggat gatcttaccg atgataacat
    33901 tttctttaag tccaaggaga tggtctttct taccacggat agctgcgtca gtaaggacac
    33961 gagttgtttc ctggaaggaa gccgctgaca agaaactgtt tgtttcaagt gaggctttgg
    34021 taattcccat aaggactggg cgacctgtcg ctggaactcc acctgcgata aggacatctt
    34081 tgttggcatc tgtaaagtca ttgatatcca tgagggtacc catgagaaga tctgtatcac
    34141 ctggatccat gacacggact ttacggatca tttgacgaac cattacctcg atgtgtttgt
    34201 caccgatttc taccccttgg ctacggtaaa ctttttgtac ttcaccgaga aggtacgttt
    34261 caactgacaa gacatcacga actgcaagga gacgttttgg ttggatagaa ccttctgtca
    34321 gagcagcacc acgcgctact tggcccccaa cttcgacacg catacgagct gtaaatggaa
    34381 cgacatattc accttcgcca gtttcaccct taacaaagac tttcttggta cgagttgatg
    34441 catcctcttc gatagcagta acttgtcctt taacctctgt gataaccgct tcccctttag
    34501 gattgcgggc ttcaaagatt tcttggacac gaggaagacc ctgagtgata tcggtatttg
    34561 aggcaacccc acctgtgtgg aaggtacgca ttgtaagctg tgtaccaggt tccccgatag
    34621 attgggcagc gattgtacca actgcttcac caacttcaac cgcatcacca gtcgccaagt
    34681 tgataccgta acagtgacgg cagacaccgt gacgagtgtt acatgtaaat acagaacgga
    34741 tagtcacttc ttccacacca gcattgacaa tttcacgcgc cttgtcttct gtaatcaatt
    34801 catttggacc aataatcact gcaccagttt ctggatgttt aacagttttc ttagtgtaac
    34861 gaccgttgag acgctcttcg agagactcga tcatctcttt tccttctgcg atagaacgga
    34921 tcaagagacc acggtcagtt ccacagtcgt cctcacggat gataacgtct tgggcaacgt
    34981 cgaccaaacg acgagtcaag taacctgagt cggctgtctt aagggccgta tcggtcatac
    35041 ctttacgagc accgtgagtt gagaagaaca tttccaatac cgacaaacct tcgcggaagt
    35101 ttgaaaggat tggcaattcc atgatacgtc cattcggagc agccatcaga ccacgcatac
    35161 cggcaagctg tgagaagttt gagatgttac cacgggctcc agagtccatc atcataacga
    35221 ttgggttctt aggatcttga ttagcaatca agcgtttctc aagtttttca cgggcagcac
    35281 gccattcagc tgtaacagca ttgtaacgct cgtcgtctgt gatcatacca cgacggaatt
    35341 gtttggtgat ttgttcgaca cgtttgtgtg attcttcaat gatttcagcc ttgtcatcaa
    35401 cgactgggat atcggcaata cccactgtca atcctgcaag agttgagtgg tggtaaccga
    35461 ggttcttcat gcggtcaagt agggcagaag tttctgtcgt acggaaacgt ttgaagattt
    35521 cagcgatgat atttccgagg tttttcttct tgaatggagg gttgagctca agattgctga
    35581 tagcttcctt gatatctcca ccaagtggca agaagtattt agctggaaca ccttctgtca
    35641 agttggcatt gtttggttct tgcaagtatg gtagcccctc tggcatgata tcgttgaaga
    35701 gaattttacc aactgttgta agcaagacct tatgtctttg ctcttctgtc caaggcttgt
    35761 tgaggctgtc tgttgcgata ccaacacgtg agtggaggtg aacataacca ttgcggtaag
    35821 ccataaccgc ttcgtcacgg tctttgaaga ccattccttc accttcgcga ccagcttctt
    35881 ccatggtcaa gtagtagtta cccaaaacca tgtcctgaga tggagtaact accggtttcc
    35941 catctttcgg gttcaagatg tgctcagcag ctagcatgag gatacgagct tctgcttgtg
    36001 cttcttctga aagtggtacg tggatggcca tttggtcccc gtcaaagtca gcattgtagg
    36061 cttcacagac aagtgggtgc aagcgaagag ccttaccatc aatcaagact ggctcgaagg
    36121 cttggatacc caaacggtga agggtcggtg cgcggttcaa aagcactggg tgttctttaa
    36181 tcacttcttc aaggatatcc cagatacgct catctccgcg ttccaccaag cgtttagctg
    36241 ctttgacgtt ttgcacgata tcacgggcaa cgatttcacg catgacaaat ggtttaaaga
    36301 gttcaatcgc catttcacgt ggcacaccac attggtacat cttaagagtt ggaccaacgg
    36361 cgataactga acgtcctgag aagtcaacac gtttaccgag caagttttga cggaaacgtc
    36421 cttgtttacc tttaagcatg tggctcaatg atttcaatgg acggctacct ggtcctgtga
    36481 ttggacgacc acgacgacca ttgtcaatca aagcgtcaac tgcttcttga agcatacgtt
    36541 tctcattttg aacgatgata cctggtgcat ttaactcaag caaacgagcc aaacggttgt
    36601 tacgattgat aacacggcgg taaaggtcat tcaagtcaga tgaggcaaaa cggccaccat
    36661 ccaactgcaa cattggacga agatctggtg ggataaccgg aaggatgtta agaatcatcc
    36721 attcaggttt gtttccagac ttgtaaaagg catccaaaac atccaaacga cggatggctt
    36781 tgacacgttt ttgtccagta gctgttttca attcttcttt gagttcagca atttcttttt
    36841 caagatctac ttgcttcaaa aggtcttgga tggcttccgc acccatcttg gcaacaaatg
    36901 aaccataacc atattcgcgc aagcgctctc ggtattcgcg ctctgtcatg atagacttgt
    36961 gctcaagtgg tgtatcctta ggatcaatca ccacataagc cgcaaagtag ataacttcct
    37021 cgagggcacg agggctcata tcaagggtca agcccatacg gcttggaatc cccttgaagt
    37081 accagatgtg agatacagga gctttcaatt cgatatgtcc catacgctca cgacgaactt
    37141 tcgtacgcgt tacttcaacc ccacagcggt cacaaacaat tcctctgtaa cgaatgcgtt
    37201 tgtacttacc acaagcacat tcccagtctt ttgtaggacc aaagatcact tcatcaaaga
    37261 gtccttcacg ttctggtttc aaggtacgat aattgattgt ttcaggtttt ttgacttctc
    37321 cataagacca tgaacggact ttacttggag aagctagggt gatttgcata cttttaaaac
    37381 gatttacatc aaccactatt tcttcccttt ctattctaag tgaactgctt attcttgttc
    37441 agcagcttct tctgttgctt ccgcttttgt tgctttctca gcttcttcag cttcaaaggc
    37501 tgctttagcc tcttgggctg ctttttcgcg ggctttttca aggtcatcta cgtggatgac
    37561 atcttcgtcc attccttcat ccaagtcgcg aagttccact tcttggtcat cttcgtctag
    37621 gacacgcatg tcaagaccaa gagattgcaa ttctttaaca agaactcgga aggattctgg
    37681 aacacctggt tttggaattg gtttgccttt tgtaatagct tcataggctt tcaaacgtcc
    37741 gttgatatcg tcagacttgt aagtcaagat ttcttgaagg acatttgacg caccgtaggc
    37801 ttcaagagcc caaacctcca tctcaccgaa acgttgtcca ccaaactgag ctttacctcc
    37861 gagtggttgt tgggtaacag ttgagtaagg tccgactgaa cgcgcgtgca atttatcgtc
    37921 aaccatgtgg tggagtttga tcatgtacat gactccaaca gaaacacggt tatcaaatgg
    37981 ttcaccagta cgtccatcgt aaaggatcgt tttggcatcg ctatccatac ctgcttcttt
    38041 aacagttgac caaagatctt cagaacttgc tccatcaaag actggtgtcg caatgtgaat
    38101 accaagagta cgagctgcca taccaaggtg aagctccata acctgaccga tattcatacg
    38161 tgatggcacc ccaagtgggt tcaacatgat gtcgactgga gttccgtctg gaaggtaagg
    38221 catgtcttct acaggaacga tacgagagac aacccctttg tttccgtgac gtccggccat
    38281 tttatctccg accttaatct tacgtttttg agcgatgtaa acacgaacca acatgttaac
    38341 acctgattgc aactcatctc catttacacg tgtaaagatc ttaacatcac gaacgacacc
    38401 atcggcaccg tgtggtacac gaagagaagt atcacgcact tcacgagact tgtctccaaa
    38461 gatagcgtgc aagagacgtt cttcagctga aagatctttc tcacccttag gtgttacttt
    38521 ccctacaaga atatcacctt ctttaacctc agcaccaata cggataatcc ccatttcgtc
    38581 aaggtctttg agggcatctt caccaacgtt tggaatttcg cgagtgattt cttcaggccc
    38641 aagctttgta tcgcgcgttt ctgattcgta ttcttcaagg tgaacagatg tgtagacatc
    38701 gtccttcacc aagcgttcgc tcatgataac ggcatcctcg aagttgtagc cttcccaagt
    38761 catgtaggca acgattgggt tttgtccaag cgccatttct ccattttcca tagaaggtcc
    38821 gtcagcgatg aaatcgcctt tttcaacgac atcaccaact tttacgagag tgcgttggtt
    38881 gtaagcagta cctgagtttg aacgacggaa tttttggatg tggtaaacat ccaatgaacc
    38941 atcttcacga cgaacttcta ccttgtcagc atctgcgtaa gtaactttac catcatactg
    39001 agcaatcaca gccgcaccag aatcgtgggc tgcttggtat tccataccag taccaacgta
    39061 aggtgcctga ggattaatca atggcacagc ctgacgttgc atattggctc ccatgagggc
    39121 acggttggag tcatcgtttt ccaagaaagg aatacatgct gtcgcaacgg caactacctg
    39181 ttttggtgaa acgtccatgt agtcaacaat attagctgga tactcttggt tgaccccttg
    39241 gtgacgtccc atgacaatct tctcagcaaa ggttccatct tcattcagac gagagttagc
    39301 ctgagctaca gtatattcat cttcttcatc agctgtcaac caaacaattt cgttcgtgac
    39361 aacacctgtt tcacggtcaa ccttacggta tggtgtttga acaaaaccat atttgttcaa
    39421 gtgtccgtaa gatgacaagt tattgatcaa accgatgtta ggtccttcag gtgtctcgat
    39481 tggacacata cgaccatagt gagtgtagtg cacgtcacgc acttcatatc cggcacggtc
    39541 acgagtcaaa ccaccaggtc ctaaggctga caaacggcgt ttgtgagaca actcagaaag
    39601 cgggttgtgt tggtccatga actgtgacaa ctgtgatgaa ccaaagaatt ctttaactgc
    39661 agctgttaca ggacgaatat tgataatttg ttgtggtgtc aagacttcat tgtcctgaac
    39721 agacatacgt tcacggacat tacgttccat acgagaaagt cccaaacgta cttggttggc
    39781 aagcaattca ccaaccgcac ggatacgacg atttccaagg tggtcgatat catctacacg
    39841 gccaagtcct tcagccaagt tgaggaagta gctcatctca gcaaggatat ctgcaggagt
    39901 caccgtacga accttgtcat ctgggttagc attaccaatg atcgttacga cgcgatctgg
    39961 atcagttgga gcaataacct tgaatttttg aagaacaaca ggctcagtca caacggctgc
    40021 atcgtttggg atgtagacaa tcttgttcaa gtcgccatcc aaatggcttt caatgctttc
    40081 aatcacgcta cgagtcataa tcgtaccagc ttctaccaag atttctccag tttcagggtc
    40141 taccaatggc tctgcaatgg tttggttgag caaacgtgtt ttaacattga gttttttatt
    40201 gattttgtaa cgaccaactg ctgccaagtc ataacgacgt gggtcaaaga agcgagctac
    40261 aagcaagcta cgtgagcttt cagccgtctt aggctcacct ggacgaaggc gttcgtaaat
    40321 ttctttcaag gcttcgtctg tacgagagtc cattggattc ttgtggatat ctttttcaac
    40381 agtgttgcga accaattcgc tgtcaccaaa gatatcaaag atttcatcat cacctgagaa
    40441 accaagagca cgaaccaagg ttgtaaatgg aatcttacga gtacggtcga tacgagtgta
    40501 ggtgatatct tttgagtcgc tttcaagttc caaccaagct ccacggttag ggataacagt
    40561 tgaaccatag cccaccttac catttttgtc tactttgtcg ttaaagtaaa cacctggtga
    40621 gcggaccaac tgagaaacga taatacgttc accaccattg atgatgaaag tacccatttc
    40681 tgtcatgatt gggaaatcac caaagaaaac ttcttgggtc ttgatttcgc ctgtttcttt
    40741 attgatcaaa cggaaggtta caaaaattgg tgctgagtag ctagcatcgt ggatacgagc
    40801 ttcttctagc gtgtattttg gttccttgat ttcatatcca acaaattcca actccattgt
    40861 gtctgtgaag tttgaaattg gcaatacatc ttcaaacact tccttaagac cgtggtctag
    40921 gaaagctttg aatgagtcag tttgaatttc aatcaaattt ggtaagtcaa gaacttcttt
    40981 gattcttgaa aaactacgac gggtacgatg tttcccgtat tgaacgtcat gtcctgccaa
    41041 gatgattctc ctttgtaaat aagttccaag ccttgtcaat caggcttttc taatcgtcat
    41101 atggttgtaa accccttatc accgtgtcct cttgacgaat tttcagaatc tttaagcctc
    41161 tgttacaaat gctcataatc ttgaaaaaaa gcacaaaaag agcagctaaa tctgactttt
    41221 tcagaagatt taactgctgt gagccttgtc tggacaatat ttcagacaaa acctacgaca
    41281 aatgattacc catattatac cctatttagc tagatttttc aaggggtttc agtaggtttt
    41341 tggtaaattt tttcccatag aaaacttggc atcacattcg aatcacgcta tggtacaaaa
    41401 aactgaaaaa actattgact ggaaatcatt ttcaaggtat aataataaac gttaaggcgg
    41461 tatagccaag tggtaaggca cggctctgca aaagcttgat cgtcggttca aatccgtcta
    41521 ccgccttcta taacttgatt tatcaggttt caaatgaaca gaaagcccaa tttgaagggc
    41581 ttttcttatt ttccctcgaa taaatacgta taactttaaa aacttttgga gcgagtttgt
    41641 ggcagagttc tttccatggc ataattccct tttgaaatca attgaaaaaa gcttcgtcac
    41701 gcctggtgac aaaagcctct agtttattct gtttcttctt ctatttcgac ttctgtgatt
    41761 tggactttta ccttggtaac acgtccattc ttcactttat cattggttaa gataaactgt
    41821 ttgttttggc tgaccaattc atagctgagt ttctcagtcg ttggaatagt tcccactcct
    41881 gtcaaataat aaccagcgat ggtatcaacg tcatcacttt ccagttcaac atcaaagtaa
    41941 ttattgaaat cattgagggt catagttcct tgaacaatgt aggtatcctc gccaatctga
    42001 tgaacatcta ttgctgcttt gtccgtttca tcatcaattt caccaacaat ttcctctaag
    42061 aggtcttcca aagtcaccaa accagccata ccaccgtatt catccagcaa gattgccatt
    42121 tgtctttggg tatttcgcag ttcttttagc aagtcatcca caaaaatagt ttcaggtaca
    42181 aaaagtggat cttgtaaaat tctcttccaa acaatattgt caaaaccgtc cacaaagcct
    42241 gccttaagga gactcttggt gtgaatgatt ccaattacat tgtccttatc cccatcataa
    42301 accgggatac gagaataatt ttgttttaaa atactttgga taatggcttg actatcatcc
    42361 tgaatatcca ccataaaggc atccgttcga ggcaccataa cctctcgtgc catcagttca
    42421 tcgagcgaaa agacaccttg tagcatctca atctcatcag catccaatgt ttcttcacta
    42481 tttgtcagca tataggcaat ttcatcacgg gtcatctttt catccgcatc atcgaatgac
    42541 ataggagtca aatggctcaa gaaattggtc gaagcagcta aaagccaaac aaaaggactg
    42601 actagttttc cgatcccaat gataatcggc gctgtacgaa ttgccaaggc atcctttaga
    42661 ttaagagcga ttctcttagg atataattcc ccaaaaacga tggaaatata ggtcaaaaat
    42721 gccaaggata gaaaagttgc cacggcttgt gctgtttcgc cattcccaag ccaagaggca
    42781 atcacacgtc ctagagtatc agttaaactc gcccctgata agattgtaat cagggtgatt
    42841 cctacctgaa tggttgataa aaagtggtta ggattttcta gtaccttcag caggcggatg
    42901 tagcgtctgt ctccttcttc cgccttttgt tcaactcggg cacgattaag agaaaccatg
    42961 gccatttctg tggctgagaa aaaggcattt aataccgtca agataaacaa taaaacaaat
    43021 tgtagcaaca aattctgact acttgggtct tccatagttc ttctcctaaa atagtatctt
    43081 atcctttatt atatcacaaa atttaatcca atacatatta tttttttctt agcgtaactt
    43141 ccatctctct cccaaaactg gaagttagtc taagacggat ttccactgat ttcacgcgtt
    43201 tttctcatac taaaagctag gttgtgggaa actggaagtt agttttagaa gttactattt
    43261 tttcttagca cctattctag ccctgcttaa actagtaaaa agaactccta catccataag
    43321 tgacatagga gtttaggctt atcttttact gagttacagt tacttctcca gttcggtaat
    43381 ccagttgaag tcccttttga acattgggaa ctagaacatt gaattccaat tctccatccg
    43441 aagacttggc ttcaatctgt gaagctgagg gaactaaatc ctcgtttgaa gcgtagtaaa
    43501 gggttacacg gtaacggaca cgcttgtttt ggtccaaggc tttacgcacc ttgctttcat
    43561 agtagttttg accagtcgaa tactcggctt gtgcctgatt tgcccaggct gtctgaacag
    43621 caatgttttt aggattgctt gttgaggcat caaaaccatc caaaccaccg attaaggcat
    43681 agcctaacaa atgacctcta tcgactgcat gggtataaga gccctttaga ttcttgacct
    43741 gatgccaacc tggaggagtc caagaagttg aaccattccc agtttcttta cgattcttgt
    43801 actgacgagt ggccttagac aagagggcat tagctacggt tggaacagtt tccttgccca
    43861 ctgtctttgt tttattgtca gcgtagggct tacttgaaac cttggcatct agatttgttt
    43921 tattaccatt gacgataaaa gcacctgagc cattccactc cagactcccc tttatttgac
    43981 tcttgactgc gtctgttaag acactctctg ccaatgcttg actaggagct tcagacgctt
    44041 gttttttctg actaagattg gttttgggac tattaggtgc cgactgcatc tgcttgatat
    44101 aatagctccc tgtagacaaa aacaataaca ctagcagtcc gattagtgtc tgtcttgttt
    44161 ttttgttcat atttctcctt atctttagaa aaaggctggt tctccagcct aatttcctgt
    44221 aaatttatga atcaattcct gccattttgc tggagacagg atagcccatg gatcttgacc
    44281 cttgcccaag attccataac ctaccattag accgattcct agagccagag tacctaaaat
    44341 cagtactatg atgactaaaa gtaaacgatt gattacgtag cttgatttct tattcatctt
    44401 catcgcttgc ctcaatccgc tgaatcttag cacctagctg cgccaacttc tcatggaaac
    44461 cgtagtaacc tctatccaag tgaaccaatt taccgaccac agtttctccc tgtgctacca
    44521 aacctgtcaa aatcaaggct gcactggcac gaaggtcagt tgaaagaact tctgctccct
    44581 gcaaaggctg tccaccaaca atacgagctg tatcacggat aatctcagaa tgcaagccca
    44641 tgcggcgcat ctcttctagg tgttggaaac gattttcgaa aactgtctcc accatggttg
    44701 attcgccttt tgcaactgtc atcaaggctg taaattgagc ctgcatatct gttggaaatc
    44761 ctgggtgggg caaggttttc acatgaacag cttttagatt ttctagttga gaacgaacac
    44821 gaattccttc gtcttcttca attacttcaa cacccatttc aagtaacttg gcaatcaagg
    44881 gacggttgtg ctcccagaca gcgtctcgaa tcaagacatc accaccagtc atggcagcag
    44941 ctaccataaa ggttcctgct tcgatacggt cttggactac attgtgagtc gtaccatgaa
    45001 gtttctcaac accagtaatg gttatagtct ctgtaccagc acctttgacc ttggctccca
    45061 tttcattaag gagaatggct aagtcaacaa tctcaggctc acgcgcagca ttctcaatca
    45121 ctgtcacccc atcagccaga gtcgctgcca tcatcaagtt ctgcgttgca ccaacacttg
    45181 gaaagtccat atagatatga gcgccatgca agcgttctgc cttggcttcg atgtaaccag
    45241 ctgtctgact aatcttaacc cccatagctt ccagaccttt caaatgaaga tcaataggac
    45301 ggctaccaat cgtacaacca cctggcatgg ataccttggc atgacccaca cgggcaagga
    45361 ttggccctaa tacaacgatg gaggcgcgca tcttgctgac atacttgtaa ggggcttcct
    45421 cagtgatgtc gccagtagca tccaccttga caagatgagc ttcctcatca aagtcaacct
    45481 tggcattcaa accaccaact acctgattca taataaagac atccgacaaa atcggaacat
    45541 tctgcaagac ggtctttcct tcacttgcta gaatagtcgc tgccaacaag ggtaagactg
    45601 cattttttgc tccctcgatc gtcacgcttc ctaccagacg attatcgcca ccttgaacca
    45661 caattttatc catactcgtt tcctttactc ttgattttat aataatcctc taagcgcttc
    45721 ttgccacaaa tgatacaggc taataaagaa agaactcagg atgtagccta tgacaatgct
    45781 aaaaaaggct actaataaac gaacttttct tgtattatca tctgtcactt ttaaaacctt
    45841 ctcccatcta acaagatcct ttaaaaggta aaaactcaca taaataaaga gcatatgact
    45901 acttagagtg aataataatt gaaccatttg actattatac catcttctct gtttgtgcgc
    45961 tagtttggaa acttcactca aaaattaggg attgtttttc aagtaatcaa tcgcatcttg
    46021 tagggtttta acgggcacga ttttcatatc cgtcttgatt gttttagccg cttctagggc
    46081 tgtttggtag ttgtttttcg cgtccagatg cgccttttgt tcttcttcgc taacagggtt
    46141 atcaggagca aagaaaatag cagcacctgc cctagccgaa gctacaacct tcttatcaat
    46201 acctccaatg tctcccacat taccatcgcg gtcaatggta cctgtaccgg caacaatacg
    46261 accattacga agatctgggt gagctatttg agtatagata gctagactaa acatgagacc
    46321 agcacttggg ccgccaatac cagctgttga aaagctaatt gggacattgc tgattacctc
    46381 tgtacggtca atcaagccga ttccaattcc atttttgcca ttttccaagg tgataatctt
    46441 tccttctgca gacttggttt gcccatcctc ttcataggtg accttgacgg aatcccctaa
    46501 tttttgagaa ctgacgtaat caatcaagtc tttggaacta tcaaaggtct gatcattgac
    46561 tgctgtgact gtatcagaga tattgagaat ccctttaaag gttgaattat ccgtcacatt
    46621 caaaacataa actccaaagt acttgagttc gatatcctta ccagctgttt ttagtccttg
    46681 atacttggcc atattttgcg atgtttgcat gtagaattga ttgattcgca taaattcaac
    46741 atcggaagaa ccacctgtag tctcctgagc actacgaata tctgtaaaag gtgtcaacca
    46801 agcataaatc atatgagcta aagtggcatg ttgaacacca accgtaacga attgataggc
    46861 accagcttcc ttatcttctg tgtcatttac tttaaggact tggcgaatat cttccgaacc
    46921 acctggaacc tctatataat aaggcaaggg cactacaaat gccaagaaag tcacaatcaa
    46981 ggccgcaatg acgtataagg gccatctaat cttttttttc atttcttatt tcctccaaaa
    47041 tactctcggg aacatggcag gcaatatcct gaccaaactt caaaagctct cgaacacctg
    47101 atgaactgat atagagatgt tcaggccggc tatgtaaata aatagtctct atatcagaag
    47161 acagctgatg attgtagtaa tcaaaactag cttcatattg caaatccgcc gcattcctca
    47221 acccccgtac taggaaagta gcccccagtc tttttgcaac atcgaccacc aattcatcat
    47281 gagaagccac gacttcaaca ttttccaaat gtcccaaagc cttttctagc ccccgtttac
    47341 gattttcaag agggagaaat ccttgtttgt ggggattaaa aaaaataccc acataaagct
    47401 tatcaaaaag tctgctcgcc cgttcaatga tatccagatg cccatttgtc atcggatcaa
    47461 atgagcctgt gaataagcca atcttatctg acatagactg tcaccttact aattccataa
    47521 atcttttcct tccagatacc cagacaggca atctcttctg gaagttcaac ggccttatcc
    47581 gtctcgcaca caaccataac atcttcagaa aaaagctctc tcttagccat tttttcaata
    47641 tctgctacga tttgttcctt ggcataggga gggtctaaga aaacgaggtc aaattcccca
    47701 gatacctgtt ccaatgccct ctctgcatcc atcttgagga gttgaaattt tccaacttcc
    47761 ttggtcatct ggatattttc agccacgatg gtctgagcct tacggtctcg ctccaccaaa
    47821 acagcactgg acatgccacg cgatactgct tcgatagata aaccaccact acctgcataa
    47881 aggtccaaga ctcgtccccc ttcaaagtag ggaccaatca tgttaaaaat ggctccccta
    47941 accttatccg aagtaggtct tgttgtcttg ccttctagtg tcttgagggg acgtccccca
    48001 tagattcctg atacgatttt catactgttt attataccaa attatagaca aaaagagaaa
    48061 gaaaaccgaa ccttgcggtt cgattctcta caaaatattt tcgtaagtat cgcggacttc
    48121 ttgaggccaa acacttgttt gcacttctcc gatgtgtctc ttgcgaagta ggaacatggc
    48181 catacgagat tgtccaattc ctccaccgat tgtcaatggg aataggccat tcaacaaaga
    48241 cttgtgccat tccaattcca agcggtcttc atcacctgta atttccacct gacgtctaag
    48301 agtttcttca tatacacgaa ttcccataga agacaactca aaggctccac ctaaagactc
    48361 attccagaca agaatatcac catttagacc cttgtagcca ttctcagact cgcttgtcca
    48421 gtcatcatag tctggtgcac gtccatcgtg cggtttacca tctggcaact cgccaccgat
    48481 accaatcaaa aagacggctc caaattcttt acaaatcgca ttttcacgtt ctttaggtgt
    48541 caagtctggg tagcgttcta ccaattcttc tgtatggata aaggtgattt gttttggcaa
    48601 gatagactcg atgtcatagc gggcttcaac agctagctca gtcaggcgaa tagccttata
    48661 aatcttctca actgtttctt ttagataaac gatgttacgc ttaccatttg ggataacctt
    48721 ctcccagtcc cactggtcaa cataaacaga gtgggttgca tccaaggaat cctcatctgg
    48781 acgaagggct ttcatgtgga caaagagacc ctctccttca ccaaagccaa aacgagccaa
    48841 ggtgtggcgt ttccatttag caagtgagtg caccacttca taagtagcat cagggatttg
    48901 gagaaccttg accgatactg gattttccac accagacagg ttgtcctgca ttccgtcacc
    48961 gaccttactc aagataggac cttgaacttc gacaacttct agcttatctt tcaaatactg
    49021 ggtaaaagtg tttttgacaa aggaaatttc ttcttgttga tggataaaac ttttcttcat
    49081 agacaactcc tcaaaaattt aataaacgta ttatacacct atttccaaga aaagaaaaga
    49141 gaaaatttaa aaaaaatcag tgtcactcaa aacactgatt tcatagacct tttagtcatt
    49201 gcgaccaaag atacgtagaa tacttaggaa aagattgata aaatcaagat agatgctgag
    49261 agccattgac accacccagc ctgtcgctac acgaccttgt gattgttcat aggcgaggcg
    49321 aatcttttgg ttatcccaag caatcaaccc tgaaaaaacc aaaaccatgg ctacgctaat
    49381 catataatca aagaagccac tagccaagaa aatattgact accatagcaa tcagtaaacc
    49441 aatgagagct gccatcattg ctcgaccaat cccactcaag tctttcttgg taaaaatacc
    49501 aactgccgcc atgacaaaga agagaagggc gctcgataca aaggcagata aaactgtacc
    49561 cggagtatag aaagccacca caaaactaag ggtaaagccg tttaaaacgg agtaaagtaa
    49621 aaatactgga agagcagctg gactatttct tgaagccatg ctactggcaa cgaaaaccaa
    49681 agccaactcc gcaaaagtag caatggtcaa ccagagacgc ccctgcatca aaaagtaaac
    49741 caactgagac tgaaagaccg tcaacataag gcctgatacc aaagcagata gtccgattcc
    49801 cagaccaaca aaggcataaa ccttagcgta aaattgattg agacctgcac ggtcatgtat
    49861 aatagtgtga ttcatccatt tctccttttc tgtgaacatc tttccttgat tataacaaaa
    49921 aaagttaaaa ttagcttaaa tggaagatta aaataccggc tgcaaccgca acattcaaac
    49981 tctcggcctg ccccttcatg ctaatatgga ccaactggtc tgcactttca gccataaggg
    50041 gactaattcc ttgaccctca tttcccataa ctagtacaaa attttctata gaaggcagtt
    50101 ctctgtaatc aacagaatct ttagataggg ttgttgctag cactgggata gctacctttt
    50161 tagtttcgtc aagaagcgct tgactagtca tccggtaaat gggcagatgg aaatgactac
    50221 cttgcatgga acgtagggtt ttgagactgt agatgtctgc cgacttatct gaaacaatca
    50281 ctcctgtaaa acctgctgca tccgcagttc gaatgatagt tcctacatta ccaggatctt
    50341 gcacatcttc caaaaacaag aacttgccct gactcaaatc agcttgtcct acttcttctt
    50401 tttgaaccac ggcaacaatt ccctgtggag tctgagaatc cgccaaatct agcaaaatat
    50461 cctctgacac ccagacagtt tgcgaaaaag tagctaactg atctcgataa ttttctaggg
    50521 caaagatttt ctcaatcgtc actccagctt ggacagcttc ttcaaacaag tgccagcctt
    50581 caatcaagta ggcagacttg cggtattttt tttggcgtaa tttcttggca ttttttacca
    50641 cagaattggc ttttgaggtt ataatagtca tagaaatatt ataacacaat caaaggggtt
    50701 tggtatgcaa aaggttagaa tgattgccca aggtagggta cagggagtcg gctttcgttg
    50761 gggtgtttac agcttggcac ttgaaattgg tggcatcaca ggtcgagtat ggaataacga
    50821 cgatggcaca gtggaaatct tagcccaagc agactcatct gctatcatgg caaaatttat
    50881 ccaagaaatc cgaaaaggac cgacaccttt ttcaaaagta agctacttag atgtcaaact
    50941 aagcaacttt cctccctact ctgactttaa aatcgcaaat taggtctcca gaactattgt
    51001 atattttgta aaaaaacagt agaatagaaa ggtataattt ttaaagaagg aataaaaaca
    51061 gtgaaatcta ttaaacgttt tgcactctca gctatgggag cggctatgtt gcttgtcttg
    51121 actggttgtg tcaatgtcga taaaaccaca ggtcagccaa caggatttat ttggaatacc
    51181 atcggagccc ctatggctga agctatcaag tacttcgcta ctgataaagg tctaggcttt
    51241 ggtgtcgcta tcatcatcgt aaccattatc gtgcgcttga ttatcttgcc acttggtatc
    51301 taccaatcat ggaaggcaac gcttcactct gaaaagatga acgccctcaa gcacgtcctt
    51361 gagccacacc aaacgcgtct caaagaagcg actactcaag aagaaaaact cgaagcccaa
    51421 caagctctct ttgctgctca aaaagagcac ggtatcagca tgtttggcgg tgtaggatgt
    51481 ttccctatcc tccttcaaat gcctttcttc tctgctatct actttgctgc ccaacatact
    51541 gaaggggttg ctcaagcaag ctacctaggc attcctctag gttctccaag tatgattttg
    51601 gttgcctgtg ctggtgtcct ttactatctt caatcgctcc tttcacttca cggagtagaa
    51661 gatgaaatgc aaagagaaca aatcaagaaa atgatttaca tgagcccact catgatcgtc
    51721 gtcttctccc tcttctcacc agctagtgtc acactttact gggttgtcgg tggtttcatg
    51781 atgattctcc aacagtttat cgtcaactat atcgttcgtc caaaacttcg caaaaaagtc
    51841 cgtgaagaac tagccaagaa cccaccaaaa gcaagtgctt tctctaaacc aagtggacga
    51901 aaagacgtta cccctgaaca accaactgct atcacaagca agaaaaaaca caaaaatcgc
    51961 aacgctggaa aacaacgttc gagataagaa gaaaaaggct tagctgattt gctaagtctt
    52021 tttgcaaatc aaaagcccga tgtttccatc aggcttcttt tctatccatg tacacgtttc
    52081 atataatctt gataactttc ggtatccatg agttttttag cgttcttgac gcgatctgct
    52141 gttggtggtt tgactccttc gagggaatat ggaattccaa gttcacgcca cttgaactca
    52201 cccatggtgt gataaggtag aatttcaaac ttatcaacat ttttgagggt cttgacgaac
    52261 ttaccaagtt caatcaagtc atcatctctg tctgtcaatc ctggaactag cacgtggcga
    52321 atccagacag gttttccaat atctgataga tactgggcac aagccaagat atttttattg
    52381 gtttgtctag tgacaatctt gtgctgttct tcgttgattt ccttgatatc caaaagaacc
    52441 aagtcagtga cagccatgag tttgtcaaac ttctcaaggt aacgtggttt attacggaaa
    52501 ggaagagcac aggtatccaa ggtacagtgg attccttgtt ccttagcctt ggtgaagaga
    52561 gcaatcagga aatcaatctg caagagagct tctcctccac tgactgtaat cccaccctta
    52621 tttccccaga aaccacggta gcgcaaggcc tctgtcaaga catcatctac cgtccgttca
    52681 cgtgacttat tggactccat agcccaagtg tctgggttgt ggcaatactg gcaacgcatg
    52741 tgacagccct gcaaaaagac aataaagcga ataccaggcc catctactga cccaaagctt
    52801 tctgtcgaat gcaccattcc tgtcacttgt ccataatcaa ttgtttcttc agacatatcg
    52861 ttaccttcct tgaaaacgtt ttatagtttt attatatcac gacttgaagg aaaaacaaga
    52921 tttttgccta ttttttagaa agcaatctgt ttttcaattt cattttcaat ctattatcag
    52981 attattcttc aaaatcgaag ccatataagg ttgcaaaata gtcctcaggg cgctctgcac
    53041 ggcggatttg acgggcttta ccttcttcgg tatagaggat ttccgcagaa cgtaatttgg
    53101 cattatactg gtagcccatt gaaaatccgt gggcacctgt atcatgaatt accagcaaat
    53161 caccgatttc tgtatgaggc agttcgcgat tgactgcaaa tttatcattg ttttcacaga
    53221 gtgaaccaac cacatctacc gcttcagctg gtccatctgg atgggtcacg ttgctaatat
    53281 gatggtaagc tccgtacata gctggacgca tgaggttgac tgctgaggca tccacaccta
    53341 gataggtacg gtaggtttcc ttcttatgag tcactcttgt gactagagca ccgtgaggtg
    53401 ccagcataaa acgacccaat tcggtgaaaa tcttgacctg accaagacct gctgacgtaa
    53461 gaacttcttc atacacctta cgaactccct caccaatcaa ggcgatatcg ttcggctcct
    53521 ggtctggacg ataattaaca ccaataccgc cagaaagatt gataaagtct agccaaatgc
    53581 ccaacttttc cttgatttca acagccagtt caaagagctg acgagccaac tctggataat
    53641 agagatgggt cacggtattg gacgctagga aggagtgaat cccaaaagtc ttggctcctt
    53701 tttccttcaa gatagcaaag gcttcaaaga gctggtcctt ggtcatgcca aacttagcct
    53761 ccccaggatt gtccataatg tctgtcccca gttcaaaaac gcctccagga ttataacgac
    53821 aagagatgat ttctggaatg cctgctactc tctccagatg ttcaatatct tcaaaggcat
    53881 ccaagttaat ggtcgcaccc aattcacgtg cataggcgta ttccttgtct ggcgtgttgt
    53941 tggaagagaa cataatctca gaacccagaa agtccagttt atggctcatc aaaagctcta
    54001 cataactaga gcagtccaca ccacaacctt cttcttggag aattttcaaa atagctggag
    54061 ttggagtagc cttaactgca aaatattcct taaagccctt gttccacgaa aaagcttggt
    54121 tgacggctct tgccttctca cgaatcccct tctcatcata caagtgaaag ggagtcggga
    54181 actcggcaac aatcgcttct aactcttctc tattgataaa tggtgttttc ataagcttcc
    54241 ttctattctg tttgcaaaga aaggctggga caatcgttcc aacctttagt tctatctctt
    54301 atttatcttc gtcaaagata ttgccaacct caacatcgat ggcttggttc ttgacatcaa
    54361 tattagttac cttcaagagt gacttgtagt caaactgctt ttcacgttct tcttgggcat
    54421 tgtccgcaaa gaccgctaca cctgccagtt ctgagtcgaa ctcgcgcaag agactaatca
    54481 taccgttgac cgttccgcca cctttcaaga agtcatccac aatcaagaca cggctacctg
    54541 ccttaagact acgttttgaa aggaacattt tctcgatacg gtcaccactt gaacctgaaa
    54601 catagttgac gctaacagtt gaaccttcgg taattttcag gtcacggcgc acaatgacaa
    54661 aagagacatt gaggacattg gcaactgcat ttgcaagtgg cacaccctta gttgctacgg
    54721 tcataaccgc gtcaattttt tggtccataa agcttttggc aataatacga ccaatatttt
    54781 tcaagatggc tggtgtgcta agcaaatcag acagatagat ataaccacct ggcaagatac
    54841 ggtcactttc tgacaacttg gtacgcaagt cttcaaccat ttccttagca tcctgactcg
    54901 aaatagacgg tgtgaagatg acacctccgc cagccccagt cactgtctgg atatgaccga
    54961 tttcaatttc ctcaaaggcg cgtttgataa tgacgatatc ttctgagatg gatgatttag
    55021 cagactcata cttttcagca aaagtattga gactagttag tttataagga ttattaatca
    55081 aatagttgga aatgacaacc atccgatcac ttcttcttaa tttcatttct atttcctatt
    55141 ccatttttat tcaaaaaatc aaaaagcaaa ctagaaagct ggtcgctggt ggttcaaaac
    55201 actgttttga gattgtcaat agaactgaca aaccctgtaa tatacctgca tatatacata
    55261 cgacaaggcg atactaccct agtttgaaga gattttcgaa gagtattcat ttttgtcttt
    55321 tacttattat accatattca cataaaaaaa cgaacattct tatcctaaaa aatgctcatt
    55381 tttcttaaat tattaatcta aatctggttt atagaaggaa cgattatcca tagcgaagat
    55441 tttattggtc atctctcctt tatccaccaa agcaagagct gttgacatca tcatcatgct
    55501 tgcatccaga ttgtcaatca tatggataat ctctgcttcc ataatgcgtg gacggactgg
    55561 gcttccatac tcaagcaagc cgtggtgact gaggatgaca tgacgaagca aaacgacttc
    55621 ttccttggta tcatcgatgc cgagttccat aactgtcttg gtaatttcgc tatcaatgag
    55681 agcgatatgt ccaagaagat tacctcgcac tgtgtactct gtctggtctg gccccgtcaa
    55741 ctcgatgacc ttagctaagt catgcaacat aatccccgca tagagcaggc tcttattgag
    55801 ctgaggataa acttcgctaa tagcgtctgc caaacgcacc atggtcgccg tatgataggc
    55861 caagcccgtt tcaaaggcat ggtggttggt cttggcagct ggataggagt agaattcctt
    55921 atcatacttg gtgtagagat ttcggacaat ccgttgccag acaggatttt caattttgaa
    55981 aatcatttgc gacatgtagt cacgaatttc cttgacatca actggtgact tgaccttgaa
    56041 atcggctggg tcattgggtt caccagcttg aggcaggcgg agagtaattt gattgacttg
    56101 aggggtattg ttataaactt ctcggcgtcc tttcatgtgg acaaccttac ctgcggtaaa
    56161 ggcctcaatg ttatgaggtt gggcatccca gagcttccca tcaatctcgc cactatcatc
    56221 ttggaaggta aaggctaggt agtttttccc agctcgagtt tgcctcaggt cagctgattt
    56281 gattaggtaa aagccttcaa atagctcatc ttttttcatg tgactaatct tcatattctt
    56341 cctcattttc ttgaaaatgg agtagatcaa gcgcaggctc gccttctgac aactcaatgt
    56401 gacggagcgt ccgctcgata gctatggtac gacggtttaa taattcatca atattgccag
    56461 aggcatgttg gagatgtttt tgtgccttga ccagaatacc accaaacttg ccaaactcgg
    56521 tcttgacact ggcaagagtc ttgctgatat ggtcggcact cttttggata ttaagggtct
    56581 tgaaaccaac tgatagggag ttaagaaggg ctgatagggt acttggtcct gcaacgataa
    56641 tctgttcttc ccgtctcaaa tcatcaaaga agaccggatt gcgcacaatc tctgaataaa
    56701 gaccttctgt cggaacaaac aaaactccaa aattggtcgt ccgaggcggt gctatgtact
    56761 tgctcttgat atccttggca aagcgcttga cgcttgctag gagtgactta cgacagcgtt
    56821 caatctcatc cttgtcacct gtctcatagg cttcttccaa gcggtaataa tctgccagtg
    56881 gaaacttaga gtcaattggc agatagacgt attcttggtc gccttgtccg ggtaacttga
    56941 tggcatactc cactcgttca ctagagtttt caaccgttgc gtattctcgt tcgtactggg
    57001 caggtgtcat gatgtcttca ataatttgcc ccagttgcaa ttctcccaga atccctcgcg
    57061 tcttggttcc agagagaacc ttgttaagag ctccgacatc acgggcaact gtctgcattt
    57121 ctccaaggcc acgattgaca gactccagtt gtttagaaac tgtctcaaag gaagcctgta
    57181 agcgtgtctg caaggtcttt tctagttttt cctcgaccgt ctggcgcatt tgttccaaac
    57241 gttgctcatt tgattcctgc aaggcttgga gacgttggtc tgtcttgtct ctagtttgga
    57301 ggagattatc tgtcatttct tgacggactt gggtcagacc ttggtgcaat tcaatccgca
    57361 cttcttgcaa acggtcgctg acaaccactt ccaaatcttt ttggtctaac tggctggctt
    57421 gtctggcttg gtcaaagcgg taatccaact ggtctgacaa atgatctgcc tgatcctcca
    57481 agctcttact taagtgtttc tcctgcctat cctgcctttg ccaaatcaga aagagaccag
    57541 ctaggttggc aattaataat agaataagta aactttccat cctacctcct gtccttgcta
    57601 tgcagtacga ccacataacc atctgggcaa gttaccgaca cttccctatc tatatattcg
    57661 ttagaagcgt acactttttt aaagaaaaaa ttttcctctg tcaactcata cttggctcca
    57721 agaatagtca gctggctatc ccgaactggc ataaaggcta gatagtcgta gtctgaacga
    57781 ggttctagct gactggtccc ttctggacaa taagtaatca agttttgccc atcctcaatt
    57841 tctatttgat gcatataggg tgccaactta ggattgctag gcagaaagac attggccaac
    57901 atatggtcaa tacggccacc caaggcaccg aaaatagtaa cctgagcctg aggatttttc
    57961 tcaaagatgg ttaagagagc caattccaaa tcggtatcat ctttttctgg tcgggcttgg
    58021 acaaaatgct gggcacgttt ttgaatcacc tgtcgctctt cttcggtcac agaatcaaaa
    58081 tccccaactg ctagagcaag aagcaagtct tcttccaaga cccagagcga gcctcgatcc
    58141 accccaacaa aagcatcaaa atctgtccga taatgaccgc ggtctccgcc tgcaaaaacg
    58201 gcaaccctag tccagttgtt ttctgagagt ttgtactcgc tcattgacat ctcccttaaa
    58261 gacataggaa cctgctacaa aaacggtcgc accagcttct ttggcttggg caatagtttg
    58321 gtcatcaatc ccaccatcca cttcgatttc aaagttcaaa cctttttcct cacgaagagc
    58381 aaccaactca cgaaccttat ccatggtttc tggcagaaag gcttgcccac caaaacctgg
    58441 attaaccgtc atgactaaaa cttggtcaac tagatgaagg acgtgcttga tggcttcaac
    58501 tgatgtgcca ggattgataa cgactgaagg cttaactccg agtgaacgaa ttttttggag
    58561 ggcgccatga atatgaggcg ttgcttctac atggatactg atgatgtctg cacctgcacg
    58621 cgcaaaatct tccagatgat gctcagggtt tgacaccatc aagtggcaat cgaaaaccat
    58681 cttactatga ggacgaaggc tctcgaccac acctgcacca aaactgattt gcggtacaaa
    58741 atgactgtcc atgatatcga tatgggcata ttctgcccca gttgcttcta gacgtttgat
    58801 ttcacgttca aagttggcat aatctgctgc cagaattgac ggagcaatct tgtattgaga
    58861 cataggtttc tccttatttt ggaatttttt tgctgacttt tttataggtt tctctacgat
    58921 tttcaatttc actaaggaat tgcaggtaat tgtcaaaacg gaaggttgca ataacaccct
    58981 cttcaacagc tggtttgacg gcacaagacg gctcatgggt atgggtacaa gtacggaact
    59041 tacaatctcg gctaacagta gcaatctctg gaaaggcctg attgaggtct tcagcccttg
    59101 atacttcata gtccagagat gaaaagcctg gtgtatctgc gattttaccc ccgttgagat
    59161 tgtaaaaact aacagctcga gtggtatggc gaccgcgacc tagactgtct gaaatttctc
    59221 ccgtttcaag attgaggtct ggtgcgattt tattgagaag agttgacttc ccaacacctg
    59281 tctgccccat aaagaccgta accttgcctg ttaacaaaga caggagttcc tctttactgg
    59341 tcacaaagtc atagccgatg tcaccatagg tctgctggta aaaatccagt tctcccctat
    59401 cttccaacaa atccattttg gaaatataga caatgggatg gatgcccttg tgctccaaaa
    59461 gaaccaagaa acgatccagc aaattgctgt taaaatcagg ttccttgacg gacatgatta
    59521 ctacagcttg atcgatattg acaataggcg gacgaaccag actgtttttc cgttcgtgaa
    59581 ttttgaggat atagccttct gaattttcct cggcagagaa atctacccag tccccaacat
    59641 aaggggtatg gcctttttta cggaaattcc cacgcgcgcg tgtttgataa acctggccat
    59701 cactctccac atagtagaaa cctgccaagg ctttaatgat ttgtccctgc atcttagagt
    59761 ccttgccctt taagtgcgtc tgctagaccg gcaaattctg ccaagctgag agcttcccca
    59821 cgcacacttg gtgacaagcc tgcctggtcc aaagccttgg tcagcttgtc cttgacctct
    59881 tcagtcttac caaagtaacc tgtcaagtta ttccacaagg tcttgcggcg atgggtaaaa
    59941 ctagccttgg aaaccttaaa gaaaaagttc tcatcttcta ctgctacggc tggctctgga
    60001 cgacgcacca ttttcaagat ggctgaatcc acatttggcg ctggcacaaa gaccgtacga
    60061 ggcacgataa aggcaacctt ggctgtcatg taatactgca cggcgataga caagctaccg
    60121 taagccttgg tgttaggctg ggctgaaatg cggtccgcta cttctttctg catcatgacc
    60181 acaaactcac aaaaaggaat gccactctca atcaagtgca tgagaatagg cgtcgtgatg
    60241 tagtaaggca aattagccac taccttgatt ggcaggttag gatttttaaa attttggata
    60301 tgttgcgcca aatcaacctt gagaatatct tcgttaacta cggtcacatt atcaaaatca
    60361 cgcagagtat ctgccaaaat tggcatcaaa cggtggtcaa tctcaaaagc catgacttgg
    60421 gctgcacgct cagccaaaaa ttctgtcaag gcaccaatac ctggcccgat ttcgatgaca
    60481 ttgacctgat catcaatttc agccgtatcc acaatttttt gaaggatatt ggtatccgtc
    60541 aagaaatttt gcccaaagga ctttttaaag gtaaaaccgt gacgctccaa cactgccttg
    60601 gtcacgctat aatctgcaat tctcatctat tctcttttct attatctgtt actactattg
    60661 taacacattc cccttgtatt ttgggaatga aaatcatacc aaaaaactat ctttcctcat
    60721 gaagaaagat agtcttggaa atctttaaag agggacttag tgcttctctc gaaacatacg
    60781 ttcatactct tcgaaaatct cttcaaacca cgtcagcttc accttgccgt actcaagtac
    60841 agcctgcggc tagcttccta gtttgctctt tgattttcat tgagtatcaa aaaaatcagc
    60901 ttcttgataa cttcgatttt cgggtagggt caaatccaca tcctcctcca catcatccac
    60961 tgtcagttca accgtctgag gtaaattttt caaacgataa tgcttttgcc tttgcccttc
    61021 aatactagca aaatcaagca aatagccatg cactcggatt tgaaccaaaa ggagatgatt
    61081 ggtcatattt tccatgatga ggatatcttc taaaccacct ctggcactag gataatcaga
    61141 taccctgcga atacggattt tttcacacat gagcaagttt cctcatatca atgatttcat
    61201 cagccttatt ccagactagg ggattatggg tcgcaatgat gataattcga ttttcatctt
    61261 tcaaatccac caagagattc ataacctcct ctgaattttc aggatcaaga gctgctgttg
    61321 gttcatctgc caaaatcaag ggtggatttt tcaaaatagt cttagcaagg gcaactcgtt
    61381 gggcctctcc cccagataaa gtataaattt tttgttctaa atccaaatac cctagattaa
    61441 ctttttctaa agcccccact tgcctttcca aacgttctac ttttgagatt ttctgaccaa
    61501 caaaacccaa atccaaattt tctttgattg attggttttc taagaggccg aaattttgaa
    61561 agagatagcc catctggtct cgaaaatact cacgagtagg aatggttttt aaatctttcc
    61621 cctgatagag aacccttcca ccatctatct tttctagctt tcccaagata ttcagcagcg
    61681 tcgtctttcc gcttccactc tttccgatta aggcataaac cttgcccttc tccagcttga
    61741 gattcaaacc agagaaaatc gcgcggtcat taaatttctt ttccaatcct tgaatatcaa
    61801 tcatcttatt ttcctttcaa tactgccatg ctaccagctt cttctttttt atcctgcctt
    61861 actaaaatca agagggcgtt aagcgtaaac aaagctacaa ctagagcgct aatcaaacca
    61921 tctcttgtca aaatactaga taggactagg ccaagcaaga gaactcctcc ttgcgccagt
    61981 aaatacttgc catgaagctc atagattgtc ataccagcaa gacgtttaat cataagttcc
    62041 cgtctgaact gctcaaaata gagaagattc atggaatcaa ataacaagat agccgtagac
    62101 agggtcaaaa tcgtcccaat aaggagagag taaaactcca cccgtttgtc atttagtacc
    62161 ttggcaaaaa atagctggct ttttaccaag taagaaacct tgtgatacag accttgctct
    62221 tttagagctg tgatgctgtc tccatatcga tctagtttca aggcactatt agccgtagtt
    62281 ccccacaaca tccctgcaac aggtcttgtt ccagtcgctt gcggcgttag aactacaata
    62341 atcggatctt ttaggtactg gcgtgttgtc ttgtacccat cattatagag gaaacgttcc
    62401 tgtcctgttt ctgtaaaagc tagccttacc tgtgggaggt agtgtttctg actcgtcact
    62461 tctacacttt cagatgaaaa gttttgcagg taatctgtaa acaatccttg gtagtaggca
    62521 gactgctctc gcaagctctc aggcaagatc agcccaaact ctccctcaga caagttttgc
    62581 atcttgtcca taaactctga agaaacggta atcttttctt ctatcagata gcgcggcgag
    62641 acatagataa cattccctaa cggtgtgtag tcactgagac gattgccatc taggtccact
    62701 tctgctccat ctgagaaatt gtcaacattg ctcataatat aaaaagagtc tgtattggct
    62761 aaccgttctt cagtaaatgt ctgccactca cgattatcct tacgcgttcc ttcttcatcg
    62821 gcaaatgcac tagaccaacc aaaggataga cggtaacggt ctgaggactg gctccattta
    62881 ttgctagctc tctccatttc ctgcatttca cggtagtggg gtaggagagc tgtcgcactc
    62941 gatccgacca ccaatacagc taagagttgc cccaccatca tcaatgtcat catacgtttg
    63001 agagggagtt tccctttcaa tagatccacc agactatttt cctgtaaacc aagtagatag
    63061 acgacactta gtaaggtaga aatccctgcc aaggtcaatc cataaagtag aagagcaatg
    63121 atgaccagtt gtaccgttgc cataaacaag gcaccttgat accagagaat ccccaatccc
    63181 aaaagactgg ataccagcac tgagcagata agctgtctca catcttctaa cactggtctg
    63241 agagcaactc caaacaagct ctcaccagct attaagcgaa tccctgcctg acgaagggat
    63301 ttgatccgat aaatcagggt cagactcata aaggtcagca gaaaaatagc taaactcagt
    63361 agcaccatag gggtggccgc caatagtaag actatcgaaa atggatcttc tccattcgaa
    63421 acaaagcctt gataaccaag ctctttcaag gtggtctgta agctcactcc atccaaactt
    63481 cctgacacaa tcaagtaaga ccctaataaa tcactcgttt ctgcactctc cttggaggaa
    63541 atggtcagac cttctggaag ctctccctca ccataagtgg cataggtaaa gagtgtttct
    63601 ccagcttcat ttggctcaac gattcgacgg gcgatgagac tattatgctc taccgccaag
    63661 tgactcaaag cctctgtcac ctcttcgcga ctagctactg gttgatttat catcattcct
    63721 gtcacatcaa cagaaggata gttaccaaat aaaatctctt ctcgatggtc aacggaagtt
    63781 atcaccatat aaagcgatac caataccatt gaaatcaaaa taaataaacg tttcatcatt
    63841 tcctccaaaa agttacttgg tcacttagtg agaaggtgac caagtaaagc taaacaatag
    63901 ggctatacca ttctaaacat tatagtagaa tgcaactttc tctccccaag aagtacgaat
    63961 ccatgcacga gaagtccctc cagcaccagc atatcccttg tcagatgaac cagtttttct
    64021 gctaacaact gttgaactat ggtattttga agggtgatag tagtttgagt aagcaccacc
    64081 gttacctgaa ccataagtcc aaacaccacc ttctgggtat tgaacggctg cagaggcaac
    64141 tgatacacct ccacctaatg ttgctgcaat gctcgctaca agagctaact ttttaactgt
    64201 ttgtttcata ttgatactcc tctatttttg attacaagat tgttgagtta cttgctcctc
    64261 tttccattat caacgttgat actattatat taccaaatga tattctaaaa ttatttgttt
    64321 ttctctaaat tgtcaaaata gcaccctgaa atgaactttt atagtcatta tactccatct
    64381 ttatcacact atcaaggaca tcaatgtcct taaaatctaa ctatttcata ttatttttag
    64441 cttatatcta aaaaaacagt tctaaagacg aactttagaa ctgttttgat acgaggacaa
    64501 ggacattttt gtcactgatt cactatgtt
//
LOCUS       DBEJHE010000011        57127 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC4 isolate 671759
            SAMN38261586-rid24793303.denovo.11, whole genome shotgun sequence.
ACCESSION   DBEJHE010000011 DBEJHE010000000
VERSION     DBEJHE010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261586
            Sequence Read Archive: SRR26833752
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 57127)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 57127)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576136.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576136.1
            Genome Coverage       :: 109x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 19:48:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,067
            CDSs (total)                      :: 2,029
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 131
            CDSs (without protein)            :: 131
            Pseudo Genes (ambiguous residues) :: 0 of 131
            Pseudo Genes (frameshifted)       :: 64 of 131
            Pseudo Genes (incomplete)         :: 59 of 131
            Pseudo Genes (internal stop)      :: 46 of 131
            Pseudo Genes (multiple problems)  :: 32 of 131
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..57127
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261586-rid24793303.denovo.11"
                     /strain="GPSC4"
                     /isolate="671759"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(32..997)
                     /locus_tag="ACL3EZ_000918"
     CDS             complement(32..997)
                     /locus_tag="ACL3EZ_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HGR0392515.1"
                     /translation="MKTSLKLYFTALVASFLLLLGACSTNSSTSQTETSSSAPTEVTI
                     KSSLAEVKLSKVPEKIVTFDLGAADTIRALGFEKNIVGMPTKTVPTYLKDLVGTVKNV
                     GSMKEPDLEAIAALEPDLIIASPRTQKFVDKFKEIAPTVLFQASKDDYWTSTKANIES
                     LASAFGETGTQKAKEELAKLDKSIQEVATKNESSDKKALAILLNEGKMAAFGAKSRFS
                     FLYQTLKFKPTDTKFEDSRHGQEVSFESVKEINPDILFVINRTLAIGGDNSSNDGVLE
                     NALIAETPAAKNGKIIQLTPDLWYLSGGGLESTKLMIEDIQKALK"
     gene            complement(1093..1845)
                     /locus_tag="ACL3EZ_000919"
     CDS             complement(1093..1845)
                     /locus_tag="ACL3EZ_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000764290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0392516.1"
                     /translation="MKLENIDKSIQKQDILQGISLEVSPQKLTAFIGPNGAGKSTLLS
                     IMSRLTKKDQGVLSIKGREIESWNSQELAQELTILKQKINYQAKLTVEELVSFGRFPY
                     SRGRLRSEDWEKIRETLNYLELTNLKDRYINSLSGGQLQRVFIAMVLAQDTDFILLDE
                     PLNNLDIKQSVSMMQILRRLVEELGKTIIIVLHDINIASQYADEIVAFKDGQVFSKGR
                     TDQIMQADLLSQLYEIPITLADINDKKICIYS"
     gene            complement(1842..2798)
                     /locus_tag="ACL3EZ_000920"
     CDS             complement(1842..2798)
                     /locus_tag="ACL3EZ_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HGR0392517.1"
                     /translation="MQTKSKHTKLFWILIILAIGACLLYFWPITHLSAFAWKLRSQKI
                     IVYLLVAIATGISTISFQTLTENRFLTPSILGIESFYVLLQTLLLVFESKFLQLGKSP
                     ILEFLVLLLVQSLFFLALQGYLKTLMKQDLVFILLICLALRSLFRNISTFLQVLMDPN
                     EYDKLQNSLFASFQHLNTSILAIGSLIILALTIFFFRKAVVLDVLHLQRETAQILGLD
                     VEKEQKELLWGIVLLTSTATSLVGPMAFFGFMLANLTYLIVKDYQHKLLFIVAILVGF
                     ISLTLGQALIERVFALEIRISMIIESVGGFLFFILLYRRARQ"
     gene            complement(2788..3747)
                     /locus_tag="ACL3EZ_000921"
     CDS             complement(2788..3747)
                     /locus_tag="ACL3EZ_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0392518.1"
                     /translation="MKLSHYLIGLLLLLVFLSISIGTSDFSWGKLFDFDQQTWLLFQE
                     SRLPRTISILLTASSMSMAGLLMQTITQNQFAAPSTVGTTEAAKLGMVLSLFVFPSAS
                     LTQKMLFAFVSSIVFTLFFLAFMTIFTVKERWMLPLIGIIYSGIIGSVTEVIAYRFNL
                     VQSMTAWTQGSFSMIQTHQYEWLFLGLIILITVWKLSQTFTIMNLGKETSESLGISYS
                     LLEKLALFLVALTTSVTMITVGGLPFLGVIVPNLVRKRYGDNLSQTKLMVALVGANLV
                     LACDILSRVLIRPYELSVSLLLGIIGSLVFILLLWRGGRKDAD"
     gene            complement(4044..4154)
                     /locus_tag="ACL3EZ_000922"
     CDS             complement(4044..4154)
                     /locus_tag="ACL3EZ_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase"
                     /protein_id="HGR0392519.1"
                     /translation="MNYLFQEDSSSQIFNLGTKKGYTIKEIFKTAEELLN"
     gene            complement(4170..4871)
                     /gene="galE"
                     /locus_tag="ACL3EZ_000923"
     CDS             complement(4170..4871)
                     /gene="galE"
                     /locus_tag="ACL3EZ_000923"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HGR0392520.1"
                     /translation="MTKTILVTGGTSYIGSHTVKALLNAGYKVHVLDNLSTGNRAAVD
                     SRASFKELDVYDASALKAYLEENQIDAVLHCAGEIVVSESIENPSKYFTANVAGMNQV
                     LKVLSEVGIQKIMFSSTASLYGNNCIDKPVTEDTLLDPVNPYAETKLMGERMIYWMAN
                     RYDWKYVIFRYFNVAGAEMDASNGLRVKNPTHIIPNINKTALGQNDSLKIFGDDYDTR
                     DGSCIRDYIYVLDLA"
     gene            5272..6336
                     /gene="pepA"
                     /locus_tag="ACL3EZ_000924"
     CDS             5272..6336
                     /gene="pepA"
                     /locus_tag="ACL3EZ_000924"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HGR0392521.1"
                     /translation="MTTLFSKIKEVTELAAVSGHEAPVRAYLREKLTPHVDEVVTDGL
                     GGIFGIKHSEAVDAPRVLVASHMDEVGFMVSEIKPDGTFRVVEIGGWNPMVVSSQRFK
                     LLTRDGHEIPVISGSVPPHLTRGKGGPTMPAIADIVFDGGFADKAEAESFGIRPGDTI
                     VPDSSAILTANEKNIISKAWDNRYGVLMVSELAEALSGQKLGNELYLGSNVQEEVGLR
                     GAHTSTTKFDPEVFLAVDCSPAGDVYGGQGKIGDGTLIRFYDPGHLLLPGMKDFLLTT
                     AEEAGIKYQYYCGKGGTDAGAAHLKNGGVPSTTIGVCARYIHSHQTLYAMDDFLEAQA
                     FLQALVKKLDRSTVDLIKHY"
     gene            6358..6654
                     /locus_tag="ACL3EZ_000925"
     CDS             6358..6654
                     /locus_tag="ACL3EZ_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HGR0392522.1"
                     /translation="MVEPNLESLIKDLYNHARHDLSEDLVAALLETTKKLPTTNEQLQ
                     AVRLSSLVNRELLLNPKHPAPELLNLARFVKREEAKYRGTATSALMYEELFKML"
     gene            7336..7779
                     /locus_tag="ACL3EZ_000926"
     CDS             7336..7779
                     /locus_tag="ACL3EZ_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HGR0392523.1"
                     /translation="MKDSHLLAHHIRLLNGRIFQKLLSQDPEALYRGEQGKILAVLWN
                     SETGCATATDIALATGLANNTLTTMIKKLEEQKLVIVSPCGKDKRKKYLVLTELGKFQ
                     KEVGHRVSQKLDTIFYKGFSEEEIHQFEGFQERILANLKEKENEV"
     gene            7783..8547
                     /locus_tag="ACL3EZ_000927"
     CDS             7783..8547
                     /locus_tag="ACL3EZ_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HGR0392524.1"
                     /translation="MSQQVKNAHNLYIHAIQDGRVAEAQAQSVGDTYIQHSTGVPDGK
                     EGFAAFFADFFERHPERQIKIVRTIEDGNLVFVHVHQYLNGGEAQWVTTDTFRADENG
                     CIVEHWDVIDYYRTPENDQLDQIFGDFEIKDLDKKAENKKLVRRFLTEIFQNGELEQW
                     SDYVADDLIQHNHEIGQGSAAYKNYVAEYSVTFDFVFQLLGQGNYVVSYGQTQIDGVA
                     YAQYDIFRLENGKIVEHWDNKEVMPKVEDLTNRGKF"
     gene            8562..9290
                     /locus_tag="ACL3EZ_000928"
     CDS             8562..9290
                     /locus_tag="ACL3EZ_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGR0392525.1"
                     /translation="MIEYKNVALRYTEKDVLRDVNLQIEDGEFMVLVGPSGSGKTTML
                     KMINRLLEPTDGNIYMDGKRIKDYDERELRLSTGYVLQAIALFPNLTVAENIALIPEM
                     KGWSKEEITKKTEELLAKVGLPVAEYGHRLPSELSGGEQQRVGIVRAMIGQPKIFLMD
                     EPFSALDAISRKQLQVLTKELHKEFGMTTIFVTHDTDEALKLADRIAVLQDGEIRQVA
                     NPETILKVPATDFVADLFGGSVHD"
     gene            9283..10803
                     /locus_tag="ACL3EZ_000929"
     CDS             9283..10803
                     /locus_tag="ACL3EZ_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HGR0392526.1"
                     /translation="MTNLIATFQDRFSDWLTALSQHLQLSLLTLLLAILLAIPLAVFL
                     RYHEKLADWVLQIAGIFQTIPSLALLGLFIPLMGIGTLPALTALVIYAIFPILQNTIT
                     GLKGIDPNLQEAGIAFGMTRWERLKKFEIPLAMPVIMSGIRTAAVLIIGTATLAALIG
                     AGGLGSFILLGIDRNNASLILIGALSSAVLAIAFNFLLKVMEKAKLRTIFSGFALVAL
                     LLGLSYSPALLVQKEKENLVIAGKIGPEPEILANMYKLLIEENTSMTATVKPNFGKTS
                     FLYEALKKGDIDIYPEFTGTVTESLLQPSPKVSHEPEQVYQVARDGIAKQDHLAYLKP
                     MSYQNTYAVAVSKKIAQEYGLKTISDLKKVEGQLKAGFTLEFNDREDGNKGLQSMYGL
                     NLNVATMEPALRYQAIQSGDIQITDAYSTDAELERYDLQVLEDDKQLFPPYQGAPLMK
                     EALLKKHPELERVLNTLAGKITESQMSQLNYQVGVEGKSAKQVAKEFLQEQGLLKK"
     gene            11148..11954
                     /gene="pnuC"
                     /locus_tag="ACL3EZ_000930"
     CDS             11148..11954
                     /gene="pnuC"
                     /locus_tag="ACL3EZ_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015663 - nicotinamide mononucleotide
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015890 - nicotinamide mononucleotide
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HGR0392527.1"
                     /translation="MHTYLQKKIENIKTTLGEMSGGYRRMVAAMADLGFSGTMKAIWD
                     DLFAHRSFAQWIYLLVLGSFPLWLELVYEHRIVDWIGMICSLTGIICVIFVSEGRASN
                     YLFGLINSVIYLILALQKGFYGEVLTTLYFTVMQPIGLLVWIYQAQFKKEKQEFVARK
                     LDGKGWTKYLSISVLWWLAFGFIYQSIGANRPYRDSITDATNGVGQILMTAVYREQWI
                     FWAATNVFSIYLWWGESLQIQGKYLIYLINSLVGWYQWSKAAKQNTDLLN"
     gene            complement(12121..12657)
                     /locus_tag="ACL3EZ_000931"
     CDS             complement(12121..12657)
                     /locus_tag="ACL3EZ_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HGR0392528.1"
                     /translation="MTNIDRRISKTKKAIYQAFIQLLNAKDYETTTVQDIIDLADVGR
                     STFYCHYESKELLLDQLCRYLFHHLFEREQAISTEDYLAHLFLHFQKNQDHIASLLFS
                     KNDYFLRQLQRELEHHVYPMLAADLKQTHPSLPTSYLQHFVVTNFIETLTWWLKKGQD
                     FTDQEVVQFYLDLLIPKN"
     gene            12790..13680
                     /gene="czcD"
                     /locus_tag="ACL3EZ_000932"
     CDS             12790..13680
                     /gene="czcD"
                     /locus_tag="ACL3EZ_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter
                     CzcD"
                     /protein_id="HGR0392529.1"
                     /translation="MKAKYAVWVAFFLNLTYAIVEFIAGGVFGSSAVLADSVHDLGDV
                     IAIGISAFLETISNREEDNQYTLGYKRFSLLGAVVTAVILVTGSVLVILENVTKILHP
                     QPVNDEGILWLGIIAITINLLASLVVGKGKTKNESILSLHFLEDTLGWVAVILMAIVL
                     RFTDWYILDPLLSLVISFFILSKALPRFWSTLKIFLDAVPEGLDIKQVKSDLERLDNV
                     ASLNQLNLWTMDALEKNAIVHVCLKEMEHMETCKESIRIFLKDCGFQNITIEIDADLE
                     THQTHKRKVCDLERSYEHQH"
     gene            13924..14277
                     /gene="nmlR"
                     /locus_tag="ACL3EZ_000933"
     CDS             13924..14277
                     /gene="nmlR"
                     /locus_tag="ACL3EZ_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="stress response transcriptional regulator NmlR"
                     /protein_id="HGR0392530.1"
                     /translation="MNIKSASDLLGISADTIRYYERVGLVPPITRTATGIRDFQDQDI
                     EALEFIKCFRSAGVSVDSLVDYMSLYQKGDETREERLGILEEEKQKLEERLSQLQTAL
                     NRLNLKIKLYKEGKF"
     gene            14278..15304
                     /locus_tag="ACL3EZ_000934"
                     /pseudo
     CDS             14278..15304
                     /locus_tag="ACL3EZ_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833740.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding dehydrogenase"
     gene            complement(15350..16357)
                     /gene="galR"
                     /locus_tag="ACL3EZ_000935"
     CDS             complement(15350..16357)
                     /gene="galR"
                     /locus_tag="ACL3EZ_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator GalR"
                     /protein_id="HGR0392531.1"
                     /translation="MATLKDIAQLASVSIATVSRVLNRDQSLSVTEETRHRILTVAEE
                     LGYTKHLKTGESHKPKQKIAIIQWVSEQGELDDLYYYQIRLGIEKRAQELDYDILRYF
                     NDHPFTLSEEVIGILCIGKFSRAQISAFEEYQKPLVFLDSDTLSLGHTCIITDFYTAM
                     KQVVDYFLSQGMDRIGILTGLEETTDQEEIIEDKRLENFRNYSQAKGIYHDELIFQGN
                     FTAQSGYDLMKEAIQNLGDQLPPAFFAASDSLAIGALRALQEAGISLPDRVSLISFND
                     TSLTKQVYPPLSSITVYTEEMGRAGMDILNKEVLHGRKIPSLTMLGTRLTLRESTLNQ
                     E"
     gene            16521..17699
                     /locus_tag="ACL3EZ_000936"
     CDS             16521..17699
                     /locus_tag="ACL3EZ_000936"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004335 - galactokinase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA];
                     GO_process: GO:0046835 - carbohydrate phosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HGR0392532.1"
                     /translation="MAQHLTTEVLRKDFLAVFGQEADQTFFSPGRINLIGEHTDYNGG
                     HVFPAAISLGTYGAARKRDDQVLRFYSANFEDKGIIEVPLADLKFEKEHNWTNYPKGV
                     LHFLQEAGHVIDKGFDFYVYGNIPNGAGLSSSASLELLTGVVAEHLFDLKLERLDLVK
                     IGKQTENNFIGVNSGIMDQFAIGMGADQRAIYLDTNTLEYDLVPLDLKDNVVVIMNTN
                     KRRELADSKYNERRAECEKAVEELQVALDIQTLGELDEWAVDQYSYLIKDENRLKRAR
                     HAVLENQRTLKAQAALQAGDLETFGRLMNASHVSLEHDYEVTGLELDTLVHTAWAQEG
                     VLGARMTGAGFGGCAIALVQKDTVEAFKEAVGKHYEEVVGYAPSFYIAEVAGGTRVLD
                     "
     gene            17718..19199
                     /locus_tag="ACL3EZ_000937"
     CDS             17718..19199
                     /locus_tag="ACL3EZ_000937"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HGR0392533.1"
                     /translation="MTLVDKFVTHVISESSFEEMDRIYLTNRVLARVGEGVLEVETNL
                     DKLIDLKDQLVEEAVRLETIEDSQTAREILGTELMDLVTPCPSQVNRDFWEAYAYSPE
                     QAIEDFYQLSQKNDYIKLKAIAKNIAYRVPSDYGELEITINLSKPEKDPKEIAVAKLV
                     QASNYPQCQLCLENEGYHGRVNHPARSNHRIIRFEMVGQEWGFQYSPYAYFNEHCIFL
                     DGQHRPMAISRQSFERLLAIVEQFPGYFAGSNADLPIVGGSILTHDHYQGGRHVFPME
                     LAPLQKTFRFAGFEQVKAGIIKWPMSVLRLTSDSKEDLINLADKIFQEWRQYSDSSVQ
                     ILAETDGTPHHTITPIARKRDGQFELDLVLRDNQTSAEHPDGIYHPHKDVQHIKKENI
                     GLIEVMGLAILPPRLKEEVEQVASYLVGEAVTVADYHQEWADQLKSQHPDLTDKEKAL
                     AIVKDSVGAIFVRVLEDAGVYKQTEQGQTAFMRFVEQVGISLD"
     gene            19269..19673
                     /locus_tag="ACL3EZ_000938"
     CDS             19269..19673
                     /locus_tag="ACL3EZ_000938"
                     /EC_number="3.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016790 - thiolester hydrolase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HGR0392534.1"
                     /translation="MKDFHFDAISAFENYEIEKMRDGHVVVTTKVVNSSLNYYGNAHG
                     GYLFTLCDQISGLVVISLGLDGVTLQSSINYLKAGKLDDVLTIKGECVHQGRTTCVMD
                     VDITNQEGRNVCKATFTMFVTGQRSEERRVRI"
     gene            19854..20618
                     /locus_tag="ACL3EZ_000939"
     CDS             19854..20618
                     /locus_tag="ACL3EZ_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type-2 restriction enzyme DpnI"
                     /protein_id="HGR0392535.1"
                     /translation="MELHFNLELVETYKSNSQKARILTEDWVYRQSYCPNCGNNPLNH
                     FENNRPVADFYCNHCSEEFELKSKKGNFSSTINDGAYATMMKRVQADNNPNFFFLTYT
                     KNFEVNNFLVLPKQFVTPKSIIQRKPLAPTARRAGWIGCNIDLSQVPSKGRIFLVQDG
                     QVRDPEKVTKEFKQGLFLRKSSLSSRGWTIEILNCIDKIEGSEFTLEDMYRFESDLKN
                     IFVKNNHIKEKIRQQLQILRDKEIIEFKGRGKYRKL"
     gene            20615..21076
                     /locus_tag="ACL3EZ_000940"
     CDS             20615..21076
                     /locus_tag="ACL3EZ_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DpnD/PcfM family protein"
                     /protein_id="HGR0392536.1"
                     /translation="MKTKQLVASEEVYDFLKVIWPDYETESRYDNLSLIVCTLSDPDC
                     VRWLSENMKFGDEKQLALMKEKYGWEVGDKLPEWLHSSYHRLLLIGELLESNLKLKKY
                     TVEITETLSRLVSIEAENPDEAERLVREKYKSCEIVLDADDFQDYDTSIYE"
     gene            complement(21127..22389)
                     /locus_tag="ACL3EZ_000941"
     CDS             complement(21127..22389)
                     /locus_tag="ACL3EZ_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001194492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleobase:cation symporter-2 family protein"
                     /protein_id="HGR0392537.1"
                     /translation="MQTQEKHSQAAVLGLQHLLAMYSGSILVPIMIATALGYSAEQLT
                     YLISTDIFMCGVATFLQLQLNKYFGIGLPVVLGVAFQSVAPLIMIGQSHGSGAMFGAL
                     IASGIYVVLVSGIFSKVANLFPSIVTGSVITTIGLTLIPVAIGNMGNNVPEPTGQSLL
                     LSAITVLIILLINIFTKGFIKSISILIGLVVGTAIAATMGLVDFSPVAVAPLVHVPTP
                     LYFGMPTFEISSIVMMCIIATVSMVESTGVYLALSDITKDPIDSTRLRNGYRAEGLAV
                     LLGGIFNTFPYTGFSQNVGLVKLSGIKKRLPIYYAAGFLVLLGLLPKFGALAQIIPSS
                     VLGGAMLVMFGFVSIQGMQILARVDFANNEHNFLIAAVSIAAGVGLNNSNLFVSMPTA
                     FQMFFSNGIVVASLLAIVLNAVLNHKKK"
     gene            complement(22389..22970)
                     /locus_tag="ACL3EZ_000942"
     CDS             complement(22389..22970)
                     /locus_tag="ACL3EZ_000942"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016763 - pentosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0043101 - purine-containing compound
                     salvage [Evidence IEA];
                     GO_process: GO:0046110 - xanthine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HGR0392538.1"
                     /translation="MKLLEERILKDGHILGDNILKVDSFLTHQVDFSLMREIGKVFAE
                     KFAAAGITKVVTIEASGIAPAVFTAEALNVPMIFAKKAKNITMNEGILTAQVYSFTKQ
                     VTSTVSIAGKFLSPEDKVLIIDDFLANGQAAKGLIQIIEQAGATVQAIGIVIEKSFQD
                     GRDLLEKAGYPVLSLARLDRFENGQVVFKEADL"
     regulatory      complement(23370..23465)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            complement(23848..23976)
                     /locus_tag="ACL3EZ_000943"
     CDS             complement(23848..23976)
                     /locus_tag="ACL3EZ_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000646799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-1-phosphate uridylyltransferase"
                     /protein_id="HGR0392539.1"
                     /translation="MKANYPIYRPLTKRKFRVSDPYIYPHEFAVLDPNGYFLRFSE"
     gene            complement(24087..24230)
                     /locus_tag="ACL3EZ_000944"
     CDS             complement(24087..24230)
                     /locus_tag="ACL3EZ_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HGR0392540.1"
                     /translation="MDYNAVIPELLVSNIEQSRSFYCGLLGFRIEYQRPEENFLFLLK
                     SVN"
     gene            complement(24242..25069)
                     /locus_tag="ACL3EZ_000945"
     CDS             complement(24242..25069)
                     /locus_tag="ACL3EZ_000945"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HGR0392541.1"
                     /translation="MKLISWNIDSLNAALTSDSARAKLSQEVLQTLVAENADIIAIQE
                     TKLSAKGPTKKHVEILEELFPGYENTWRSSQEPARKGYAGTMFLYKKELTPTISFPEI
                     GAPSTMDLEGRIITLEFDAFFVTQVYTPNAGDGLKRLEERQVWDAKYAEYLAKLDKEK
                     PVLATGDYNVAHNEIDLANPASNRRSPGFTDEERAGFTNLLATGFTDTFRHVHGDVPE
                     RYTWWAQRSKTSKINNTGWRIDYWLTSNRIADKVTKSDMIDSGARQDHTPIVLEIDL"
     gene            25203..25658
                     /locus_tag="ACL3EZ_000946"
                     /pseudo
     CDS             25203..25658
                     /locus_tag="ACL3EZ_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730499.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3290 family protein"
     gene            25655..25792
                     /locus_tag="ACL3EZ_000947"
     CDS             25655..25792
                     /locus_tag="ACL3EZ_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000174438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0392542.1"
                     /translation="MTLNYIEILIKLVLTLKWLNNNVHFVKRLIDGKPTLLIKNGNIA
                     P"
     gene            25811..26107
                     /locus_tag="ACL3EZ_000948"
     CDS             25811..26107
                     /locus_tag="ACL3EZ_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001276342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HGR0392543.1"
                     /translation="MSASDVALKLRSQGIFQMKQVKRAVQEQNGQLIVVQMGDENPKY
                     PVVTDGVIQVDVLESIGRSEEWLLDNLSKQGHDNVANIFIAEYDKGAVTVVTYE"
     gene            26313..28058
                     /locus_tag="ACL3EZ_000949"
     CDS             26313..28058
                     /locus_tag="ACL3EZ_000949"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0392544.1"
                     /translation="MSIIQKLWWFFKLEKRRYLVGIVALVLVSVLNLIPPMVMGRVID
                     AITSGQLTQQDLLLSLFYLLLAAFGMYYLRYVWRMYILGTSYCLGQIMRSRLFKHFTK
                     MSSAFYQTYRTGDLMAHATNDINALTRLAGGGVMSAVDASITALVTLLTMLFSISWQM
                     TLVAILPLPFMAYATSRLGRKTHKAFGESQTAFSELNNKVQESVSGIKVTKSFGYQAD
                     ELKSFQAVNELTFQKNLQTMKYDSLFDPMVLLFVGSSYVLTLLVGSLMVQEGQITVGN
                     LVTFISYLDMLVWPLLAIGFLFNTTQRGKVSYQRIENLLSQESPVQDPEFPLDGIENG
                     RLEYAIDSFAFENEETLTDIHFSLAKGQTLGLVGQTGSGKTSLIKLLLREYDVDKGAI
                     YLNGHDIRDYRLTDLRSLMGYVPQDQFLFATSILDNIRFGNPNLPLSAVEEATKLARV
                     YQDIVDMPQGFDTLIGEKGVSLSGGQKQRLAMSRAMILDPDILILDDSLSAVDAKTEY
                     AIIDNLKETRKDKTTIITAHRLSAVVHADLILVLQNGQIIERGRHEDLLALDGWYAQT
                     YQSQQLEMKGEEDAE"
     gene            28048..29799
                     /locus_tag="ACL3EZ_000950"
     CDS             28048..29799
                     /locus_tag="ACL3EZ_000950"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0392545.1"
                     /translation="MQNKQEQWTVLKRLMSYLKPYRLLTFLALSFLLATTVIKSVIPL
                     VASHFIDQYLSNLNQLAVTVLLVYYGLYILQTVVQYVGNLLFARVSYSIVRDIRRDAF
                     ANMEKLGMSYFDKTPAGSIVSRLTNDTETISDMFSGILSSFISAVFIFLTTLYTMLVL
                     DFRLTALVLLFLPLIFLLVNLYRKKSVKIIEKTRSLLSDINSKLAENIEGIRIIQAFN
                     QEKRLQAEFDEINQEHLVYANRSVALDALFLRPAMSLLKLLGYAVLMAYFGYRGFSIG
                     ITVGTMYAFIQYINRLFDPLIEVTQNFSTLQTAMVSAGRVFALIDERTYEPLQENGQA
                     KVQEGNIRFEHVCFSYDGKHPILDDISFSVNKGETIAFVGHTGSGKSSIINVLMRFYE
                     FQSGRVLLDDVDIRDFSQEELRKNIGLVLQEPFLYHGTIKSNIAMYQEISDEQVQAAA
                     AFVDADSFIQELPQGYDSPVSERGSSFSTGQRQLLAFARTVASQPKILILDEATANID
                     SETESLVQASLAKMRQGRTTIAIAHRLSTIQDANCIYVLDKGRIIESGTHEELLALGG
                     TYHKMYSLQAGAMADTL"
     gene            29972..30664
                     /locus_tag="ACL3EZ_000951"
     CDS             29972..30664
                     /locus_tag="ACL3EZ_000951"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000922225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0006486 - protein glycosylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HGR0392546.1"
                     /translation="MLKWEDLPVEMKSSEVESYYQLVSKRKGSLIFKRCLDWVLALVL
                     LVLTSPIFLILSIWIKLDSKGPVIYKQERVTQYNRRFKIWKFRTMVTDADKKGSLVTS
                     ANDSRITKVGNFIRRVRLDELPQLVNVLKGEMSFVGTRPEVPRYTEQYSPEMMATLLL
                     QAGITSPASINYKDEDTIISQMTEKGLSVDQAYVEHVLPEKMRYNLAYLREFSFFGDI
                     KIMFQTVFEVLK"
     gene            30707..31933
                     /locus_tag="ACL3EZ_000952"
     CDS             30707..31933
                     /locus_tag="ACL3EZ_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001134527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS family aminotransferase"
                     /protein_id="HGR0392547.1"
                     /translation="MPNYNIPFSPPDITEAEIAEVADTLRSGWITTGPKTKELERRLS
                     LYTQTPKTVCLNSATAALELILRVLEVGPGDEVIVPAMTYTASCSVITHVGATPVMVD
                     IQADTFEMDYDLLEQAITEKTKVIIPVELAGIVCDYDRLFQVVEKKRDFFTASSKWQK
                     AFNRIVIVSDSAHALGSTYKGQPSGSIADFTSFSFHAVKNFTTAEGGSATWKANPVID
                     DEEMYKEFQILSLHGQTKDALAKMQLGSWEYDIVTPAYKCNMTDIMASLGLVQLDRYP
                     SLLQRRKDIVDRYDSGFAGSRIHPLAHKTETVESSRHLYITRVEGASLEERNLIIQEL
                     AKAGIASNVHYKPLPLLTAYKNLGFDMTNYPKAYAFFENEITLPLHTKLSDEEVDYII
                     ETFKTVSEKVLTLSKK"
     gene            33063..35222
                     /gene="pfbA"
                     /locus_tag="ACL3EZ_000953"
     CDS             33063..35222
                     /gene="pfbA"
                     /locus_tag="ACL3EZ_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multi-ligand-binding adhesin PfbA"
                     /protein_id="HGR0392548.1"
                     /translation="MLKIVKKLEVLMKYFVPNEVFSIRKLKVGTCSVLLAISILGSQG
                     ILSDEVVTSSSPMATKESSNAITNDLDNSPTVNQNRSAEMIASNSTTNGLDNSLSVNS
                     ISSNGTIRSNSQLDNRTVESTVTSTNENKSYKEDVISDRIIKKEFEDTALSVKDYGAV
                     GDGIHDDRQAIQDAIDAAAQGLGGGNVYFPEGTYLVKEIVFLKSHTHLELNEKATILN
                     GINIKNHPSIVFMTGLFTDDGAQVEWGPTEDISYSGGTIDMNGALNEEGTKAKNLPLI
                     NSSGAFAIGNSNNVTIKNVTFKDSYQGHAIQIAGSKNVLVDNSRFLGQALPKTMKDGQ
                     IISKESIQIEPLTRKGFPYALNDDGKKSENVTIQNSYFGKSDKSGELVTAIGTHYQTL
                     STQNPSNIKILNNHFDNMMYAGVRFTGFTDVLIKGNRFDKKVKGESVHYRESGAALVN
                     AYSYKNTKDLLDLNKQVVIAENIFNIADPKTKAIRVAKDSAEYLGKVSDITVTKNVIN
                     NNSKETEQPNIELLRVSDNLVVSENSIFGGKEGIVIEDSKGKITVLNNQFYNLSGKYI
                     SFIKSNANGKEPVIRDSDGNFNIVTENGLYKIVTNNLSDKNEKEKNKEEKQSNSNNVI
                     DSNQKNGEFNSSKDNRQMNDKIDNKQDNKTEEVNYKIVGDGRETENHINKSKEIVDVK
                     QKLPKTGSNKIMELFLTVTGIGLLLTLKGLKYYGKDK"
     gene            35206..35502
                     /locus_tag="ACL3EZ_000954"
     CDS             35206..35502
                     /locus_tag="ACL3EZ_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0392549.1"
                     /translation="MVKINKICSIQGSSVENEDIVGSQNQYFWIIGGATDLYNSKEEI
                     GYSVSEVVHILSESLSVNCKESKTLKQIFETALLEVKDEIGLNSYELTEYNKMK"
     gene            35674..36057
                     /locus_tag="ACL3EZ_000955"
     CDS             35674..36057
                     /locus_tag="ACL3EZ_000955"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0392550.1"
                     /translation="MLVNEMEITDHRVDNLFEKGKNEIKDSIGTNSVLNKKIILQKIR
                     KLSNQPSGYWIGSLDERFLDHAIINQIDVTSEQIVLMSDGFYEFYQNNQNKTFEELIK
                     MRFNSSAIDPIYGKKDDASILVIDV"
     gene            36115..36756
                     /locus_tag="ACL3EZ_000956"
     CDS             36115..36756
                     /locus_tag="ACL3EZ_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000945326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate uptake regulator PhoU"
                     /protein_id="HGR0392551.1"
                     /translation="MLRLYLENEIIELSNNLETIWVSVLDKYEKLFEYLSNEERIELI
                     KEDLIINESVLNIDKKGYELICLQYPVSYDLRRIISVIKISTDIERIGDRIVEILKNL
                     QILQNNEILKKIISEIKILHEVIGLHMNRAISCYREEQSGCLDMVVIQKQNEIEELSI
                     NMEKKIMNYIFEDDGNVSEVISALDIIHHLDKIAHTTQAIYKWIMYRKYGNIN"
     gene            36769..38244
                     /gene="galT"
                     /locus_tag="ACL3EZ_000957"
     CDS             36769..38244
                     /gene="galT"
                     /locus_tag="ACL3EZ_000957"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0017103 - UTP:galactose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0019388 - galactose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HGR0392552.1"
                     /translation="MKTIIDNFVDRVIEYGMYNEIDKIYVKNRVLALIGEEGIDRISD
                     ENDLKQIKDYLVEIALKNGKIKDLIEEKECLGAELMNFIVPLPSRLNDIFWSSYDISP
                     QEAVEEFYKLSKDSDYIKTSAIAKNIEFRASTKYGELEITINLSKPEKDPKTIAAEKL
                     VKATNYPKCLLCMENEGYQGRINYPARSNHRIIRLKLGDEVWGFQYSPYSYFNEHAIF
                     LNSQHVPMAITSKTFEQLLEIVDILPGYFAGSNSDLPISGGSILSHNHYQGGKHIFPM
                     EKAKFESEFCFKDFEDVNAGIVKWPMSVIRLQSENKNRLLDLATKILNKWREYSDLEV
                     DIIAMTEDVPHHTVTPIARKVDGRYELDIVLRDNHTTEQYPDGVFHPHQDVQHIKKEN
                     IGLIEVMGLAILPPRLKPELEEVGKYLLGEENAIADYHLEWADQLKEKYPRINKEEVN
                     NVVQHEAGQVFARVLEDAGVYKNTPSGHEAFMRFVKSVGIN"
     gene            38257..39267
                     /gene="galE"
                     /locus_tag="ACL3EZ_000958"
     CDS             38257..39267
                     /gene="galE"
                     /locus_tag="ACL3EZ_000958"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000996568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HGR0392553.1"
                     /translation="MAILVTGGAGYIGSHTVVELLNLGKEVIIVDNLSNSSILVLDRI
                     EAITGIRPVFYELDVCDKQALRKVFEQESIDAAIHFAGYKAVGESVQKPVMYYKNNIM
                     STLALVEVMSEFNVKKIVFSSSATVYGINNQSPLIETMQTSATNPYGYTKVMLEQILK
                     DVHVADSEWSIALLRYFNPIGAHESGLIGEDPSGIPNNLMPYIAQVAVGKLSELSVFG
                     NDYDTLDGTGVRDYIHVVDLAIGHIKALEKVSEKTDVYIYNLGSGEGTSVLQLVNTFE
                     SVNKIPIPYKIVPRRSGDVATCYANADKAYKELNWRTTKSIEDMCRDTWNWQSKNPNG
                     YN"
     gene            39447..40106
                     /locus_tag="ACL3EZ_000959"
     CDS             39447..40106
                     /locus_tag="ACL3EZ_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000793810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1868 domain-containing protein"
                     /protein_id="HGR0392554.1"
                     /translation="MKNLTKIKFKENGEFNHFPGNTVVANLYTKQDLMEVVDIIQSRY
                     RELPFIDKFTLTPRNSIHMTVIELLCHENRETEFWSSNLPLDTPLQEIHDYFAKQLEI
                     FPLLDEEIHMRITEMGKQNILVEPADEASAKRLEEIRTYVSEKAGVCFPNHDRYQFHI
                     SIGYLRIPLTEEEEEEFTKVRAELTEILLEKIPTITVNRIDYTVFEDMRQFVPYHEKF
                     K"
     gene            40131..41198
                     /locus_tag="ACL3EZ_000960"
     CDS             40131..41198
                     /locus_tag="ACL3EZ_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HGR0392555.1"
                     /translation="MKKMKVWSTVLATGVALTTLAACSGGSNSTTASSSEEKADKSQE
                     LVIYSNSVSNGRGDWLTAKAKEAGFNIKMVDIAGAQLADRVIAEKNNAVADMVFGIGA
                     VDSNKIRDQKLLVQYKPKWLDKIDQSLSDKDNYYNPVIVQPLVLIGAPDVKEMLKDWT
                     ELGSKYKGKYSIYGLQGGTGRAILASILVRYLDEKGDLGVSEKGWEVAKEYFANAYTL
                     QKGESSVVKALDKESPIQYGMIWGSGALIGQKEQNVEFKVMTPEIGVPFVTEQTMVLS
                     TSKKQALAKEFIDWFGQSEIQVEYSKKFGSIPANKDALKELPEDTKKFVDQVKPQNID
                     WEAVGKHLDEWVEKAELEYVK"
     gene            41302..42312
                     /locus_tag="ACL3EZ_000961"
     CDS             41302..42312
                     /locus_tag="ACL3EZ_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0392556.1"
                     /translation="MIKFDNIQIKYGDFVAIDNLNLDIHEGEFFTFLGPSGCGKSTTL
                     RALVGFLDPSSGSIEVNGTDVTHLEPEKRGIGIVFQSYALFPTMTVFDNIAFGLKVKK
                     VAPDVIKAKVSAVAAKIKISDQQLQRNVSELSGGQQQRVALARALVLEPKILCLDEPL
                     SNLDAKLRVDLRKELKRLQKELGITTLYVTHDQEEALTLSDRIAVFNNGYIEQVGTPV
                     EIYHNSQTEFVCDFIGDINVLTDETVHEVLLKNTSVFLEDKKGYIRLEKVRFNRETEQ
                     DFILKGTIIDVEFSGVTIHYTIKVSESQILNVTSIDSQAAIRSVGESVELFITPSDVL
                     QF"
     gene            42324..44015
                     /locus_tag="ACL3EZ_000962"
     CDS             42324..44015
                     /locus_tag="ACL3EZ_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0392557.1"
                     /translation="MRHKLNLKDWLIRLGLIWFLVTFIIYPNFDLVVNVFVKGGEFSL
                     DAVHRVLKSQRALQSIMNSFKLAFSLIITVNVVGILCVLFTEYFDIKGAKILKLGYMT
                     SLIYGGVVLATGYKFVYGPYGLITKFLQNVIPSLDSNWFIGYGAVLFIMTFSGTANHT
                     LFLTNTIRSVDYHTIEAARNMGAKPFTVFRKVVLPTLIPTLFALTIMVFLSGLSAVAA
                     PMIVGGKEFQTINPMIITFAGMGNSRDLAALLAIILGIATTILLTIMNKIEKGGNYIS
                     ISKTKAPLKKQKIASKPWNIIAHIVAYGLFTVFMLPLIFIVLYSFTDPVAIQTGNLTL
                     SNFTLENYRLFFSNSAAFSPFLVSFIYSIIAATTATILAVVFARVVRKHKSRFDFLFE
                     YGALLPWLLPSTLLAVSLLFTFNQPQFLVLNQILVGSLVILLIAYIVVKIPFSYRMVR
                     AILFSVDDEMEDAARSMGASPFYTMMKVIIPFILPVVLSVIALNFNSLLTDFDLSVFL
                     YHPLAQPLGITIRSAGDETATSNAQALVFVYTIVLMIISGTVLYFTQRPGRKVRK"
     gene            44018..44728
                     /locus_tag="ACL3EZ_000963"
     CDS             44018..44728
                     /locus_tag="ACL3EZ_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000127555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HGR0392558.1"
                     /translation="MTATSLGLSNIEIVVRIVLSVVIGSIIGLERGSKSQPAGIRTYS
                     IVCLAACLIMMTNEYVSYKFGTGDPTRLGAQVISGVGFLGAGTILITDKKKITGLTTA
                     AGIWASAGIGLAIGVGFYEGALLVAISVWGVISMFQPLKKYLQNRSKMIELYIVVKST
                     EAYNRVLVYCAENGIRMTDSRTAFGDVNSDRIEYFDVPDKKIASFITLELSGRFEHLR
                     LMEEIANIVGVIYVEEIS"
     gene            44824..45192
                     /locus_tag="ACL3EZ_000964"
     CDS             44824..45192
                     /locus_tag="ACL3EZ_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0392559.1"
                     /translation="MKDYKINFDLGKIEYFDNNCLIQVYKFISFYDICEMVFAFHLPP
                     DELITNVIFKEKINSMLKCYIDRLLYVFINPTHFTEKVNLQFYGSFFSYEFICREVGN
                     ILKNKGVKCNLNFFEGEEYL"
     gene            45300..46301
                     /locus_tag="ACL3EZ_000965"
     CDS             45300..46301
                     /locus_tag="ACL3EZ_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000789954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGR0392560.1"
                     /translation="MKNINGKKVTIYDIARLSGFSPKTVSRVINGGVNVKEETYQAIQ
                     KVIEELSYIPNAYAKNLTKKEAINILISVKKIDSFPLIWFHTLLDKVLRTCKEFGVNA
                     IVEYFGEEDTISNSIISSTGSLVDGVIVFYESVDDIRIQYLKKNHMPFLVFGESQTSG
                     VVYVSNNNFQATYDMMKAVTEEKFKNMWLLMGGESHVNKDRERGVRSFLNDKNYFMDL
                     KVIYGLSTIDSVYSYAMQHLTTQNYPDIIFVSGDEKVQGLIRACYEKGILIPDDISII
                     GFDNIPISQYYTPALSTIAPNYVKLAKEMIEGVLAIIKGESVTSVEVSPKFVRRQSF"
     gene            46909..47070
                     /locus_tag="ACL3EZ_000966"
     CDS             46909..47070
                     /locus_tag="ACL3EZ_000966"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0392561.1"
                     /translation="MKIKEQTRKLAAGCSKHCFEVVDRTDEVSNHTYGKATLTRFEEI
                     FEEYKGVPR"
     gene            47442..48803
                     /gene="trpE"
                     /locus_tag="ACL3EZ_000967"
     CDS             47442..48803
                     /gene="trpE"
                     /locus_tag="ACL3EZ_000967"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004049 - anthranilate synthase activity
                     [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate synthase component I"
                     /protein_id="HGR0392562.1"
                     /translation="MERIIHGDVLSPILAYMRLKGQHKVILESIPRDKETARFSILAY
                     NPVFEIKFENGVLYQNGQVIDRDPLDFLYEVIHKSQHHSELPFGGGAIGFVGYDMISL
                     YEEIGQIPEDTIGTPDMHFFVYESYMVFDHKKEKIHVIEDALYSERSQEALEKSLNQV
                     LEELRIPAPNEFEDLDLSPLDFKPHIAPHKFEGMVETARDLIRNGDMFQCVLSQRFSA
                     EVTGNPFDFYRNLRVTNPSNYLYFYDFGDYQIIGASPESLVSVKNGIVTTNPIAGTRP
                     RGAMDEEDKTLATDLLSDEKETAEHRMLVDLGRNDIGRISETASVQVTKYMKVELFRY
                     VMHLTSVVKGRLLPELTAMDALKATLPAGTVSGAPKIRAMRRIYELETEKRGVYAGAI
                     GYLSATGDMDLAIAIRTMILKNQRAYVQAGAGIVYDSIAQNEYQETINKAKSMTRIGE
                     LRP"
     gene            48800..49366
                     /locus_tag="ACL3EZ_000968"
     CDS             48800..49366
                     /locus_tag="ACL3EZ_000968"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004049 - anthranilate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0046820 - 4-amino-4-deoxychorismate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HGR0392563.1"
                     /translation="MILLIDNYDSFTYNLAQYIGNFAEVQVLRNDDSKLYEEAEKADG
                     LVFSPGPGWPVDAGKMEDMIRDFAGKKPILGICLGHQAIAEVFGGKLGLAPKVMHGKQ
                     SNINFEAPSVLYQGIEEGRAVMRYHSILIEEMPEDFEVTARSTDDQAIMGIQHKNLPI
                     YGFQYHPESIGTPDGLSSIRNFIEKVVK"
     gene            49377..50381
                     /gene="trpD"
                     /locus_tag="ACL3EZ_000969"
     CDS             49377..50381
                     /gene="trpD"
                     /locus_tag="ACL3EZ_000969"
                     /EC_number="2.4.2.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004048 - anthranilate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate phosphoribosyltransferase"
                     /protein_id="HGR0392564.1"
                     /translation="MKEIIEKLAKFENLSGVEMTDVIERIVTGRVTEAQIASLLLALK
                     MKGETPEERTAIAQVMRGHAQHIPTEIHDAMDNCGTGGDKSFSFNISTTAAFVLAGGG
                     IHMAKHGNRSISSKSGSADVLEALGINLDLKPAELGKVFDKTGIVFLFAKNMHPAMKY
                     IMPARLELGIPTIMNLTGPLIHPMALETQLLGISRPELLESTAQVLKNMGRKRAIVVA
                     GPEGLDEAGLNGTTKIALLENGEISLSSFTPEDLGMEGYAMEDIRGGNAQENAEILLS
                     VLKNEASPFLETTVLNAGLGFYANGKIDSIKEGVALARQVIARGKALEKLRLLQEYQK
                     "
     gene            50378..51145
                     /gene="trpC"
                     /locus_tag="ACL3EZ_000970"
     CDS             50378..51145
                     /gene="trpC"
                     /locus_tag="ACL3EZ_000970"
                     /EC_number="4.1.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011227478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004425 - indole-3-glycerol-phosphate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0006568 - tryptophan metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="indole-3-glycerol phosphate synthase TrpC"
                     /protein_id="HGR0392565.1"
                     /translation="MSQEFLARILEQKAREVEQMKLEQIQPLRQTYRLAEFLKNHQDR
                     LQVIAEVKKASPSLGDINLDVDIVQQAQTYEENGAVMISVLTDEVFFKGHLDYLREIS
                     SQVEIPTLNKDFIIDEKQIIRARNAGATVILLIVAALSEERLKELYDYATELGLEVLV
                     ETHNLAELEVAHRLGAEIIGVNNRNLTTFEVDLQTSVDLAPYFEEGRYYISESAIFTG
                     QDAERLAPYFNGILVGTALMQAENVAQRIKELQIDKG"
     gene            51132..51731
                     /locus_tag="ACL3EZ_000971"
     CDS             51132..51731
                     /locus_tag="ACL3EZ_000971"
                     /EC_number="5.3.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylanthranilate isomerase"
                     /protein_id="HGR0392566.1"
                     /translation="MTKVKICGLSTKEAVETAVSAGADYIGFVFAPSKRQVTLEEAAE
                     LAKLIPADVKKVGVFVSPSRVELLEAIDKVGLDLVQVHGQVADDLFENLPCASIQAVQ
                     VDGEGHVPNSQADYLLFDAPVAGSGQPFDWGQLDTTGLPQSFFIAGGLNEDNVVKAIQ
                     HFTPYAVDVSSGVETDGQKDHEKIRRFIERVKNGISRTK"
     gene            51709..52932
                     /gene="trpB"
                     /locus_tag="ACL3EZ_000972"
     CDS             51709..52932
                     /gene="trpB"
                     /locus_tag="ACL3EZ_000972"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004834 - tryptophan synthase activity
                     [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HGR0392567.1"
                     /translation="MAYQEPNKDGFYGKFGGRFVPETLMTAVLELEKAYRESQADPSF
                     QEELNQLLRQYVGRETPLYYAKNLTQHIGGAKIYLKREDLNHTGAHKINNALGQVWLA
                     KRMGKKKIIAETGAGQHGVATATAAALFNMECTIYMGEEDVKRQALNVFRMELLGAKV
                     EAVTDGSRVLKDAVNAALRSWVANIDDTHYILGSALGPHPFPEIVRDFQSVIGREAKQ
                     QYRDLTGQNLPDALVACVGGGSNAIGLFHPFVEDESVAMYGAEAAGLGVDTEHHAATL
                     TKGRPGVLHGSLMDVLQDAHGQILEAFSISAGLDYPGIGPEHSHYHDIKRASYVPVTD
                     EEALEGFQLLSRVEGIIPALESSHAIAFAVKLAKELGPEKSMIVCLSGRGDKDVVQVK
                     DRLEADAAKKGEAHA"
     gene            52925..53701
                     /gene="trpA"
                     /locus_tag="ACL3EZ_000973"
     CDS             52925..53701
                     /gene="trpA"
                     /locus_tag="ACL3EZ_000973"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004834 - tryptophan synthase activity
                     [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="HGR0392568.1"
                     /translation="MPKTLTEKLNAIKAAGKGIFVPYIMAGDHEKGLDGLAETIHFLE
                     DLGVSAIEVGIPFSDPVADGPVIEEAGLRSLAHGTSTQALVETLKTIETEIPLVIMTY
                     FNPLFQYGVENFVKDLADTAVKGLIIPDLPHEHANFVEPFLANTDIALIPLVSLTTGI
                     ERQKELIAGAEGFVYAVAINGVTGKSGNYRADLDKHLAQLHQVADIPVLTGFGVSSQA
                     DLERFNAVSDGVIVGSKIVKALHQGEPIQDFIRQAVAYQK"
     gene            complement(53673..53774)
                     /locus_tag="ACL3EZ_000974"
                     /pseudo
     CDS             complement(53673..53774)
                     /locus_tag="ACL3EZ_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234126.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
     gene            54003..54734
                     /locus_tag="ACL3EZ_000975"
     CDS             54003..54734
                     /locus_tag="ACL3EZ_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000934015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0392569.1"
                     /translation="MLNQDLFDSLEAQKIVDTLMKGQKDYVDERLEKRETMIVSNGYA
                     WTRPNHIDTAFASADLFEYKLQLAGQTWGYLEFETNTEKYGKVLLIIKGKKRLTNQFP
                     LVQKNKSGYLFEYAQMNTLYLNQHSSYKNDEDSHSFPIQMELVSDEMIQEIEQATKNS
                     NIEKFMILTYEADSENNIISVDVVMPDARTGQLHLIQDLSEYIQSSSYHFEEAKYQDI
                     PNFSELSETEDFEIIPRIEKQEGQK"
     gene            54749..55900
                     /locus_tag="ACL3EZ_000976"
     CDS             54749..55900
                     /locus_tag="ACL3EZ_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGR0392570.1"
                     /translation="MFNGRVLKELRLLNGLSRAELAQRINLTEQAIWQFESNETKPKL
                     STKMHLANQFHVDLTYFEQEEESIRFDSSVIAFRNADLATRKTIDIQTMYLHKVDSLI
                     DYFESFVIIPNIIIHDLSNVVSESYHKGESIEELALYAREKLGISKDNHDLLYKLERS
                     GIYIVERLINGQADAYSAWSKLGRPYIVLGTNKSSVRRNFDLAHELGHILLHKYKDMN
                     EDGDRLEQEANYFASCFLLPKEEFLVKFEERVGKRASNPDSYILLKSDLNVSIQALEY
                     RAFKLGLLTPKQHSYFYRQIAQKGYKMIEPLDDQIFVKKPSKVKSILDVVLSNHLVSL
                     ATIMSKQSICLQFISEIFSVEMKFFDQYQEDRRTDRFDNIIPLYKRNNL"
     gene            complement(55952..56611)
                     /locus_tag="ACL3EZ_000977"
     CDS             complement(55952..56611)
                     /locus_tag="ACL3EZ_000977"
                     /EC_number="3.4.23.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="A24 family peptidase"
                     /protein_id="HGR0392571.1"
                     /translation="MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTRLR
                     PLDLIPILSQVFNRFRCRYCKVRYPVWYALFELVLGLLFLLYSWELLSLGQVVLITAG
                     LTLGIYDFHHQEYPLLVWMTFHLILIASSGWNLVMVSFLALGILAHFIDIRMGAGDFL
                     FLASCALVFSVTELLILIQFASATGILAFILQKKKERLPFVPFLLLATCLIIFGKLLL
                     V"
     gene            56681..57127
                     /locus_tag="ACL3EZ_000978"
     CDS             56681..57127
                     /locus_tag="ACL3EZ_000978"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000155432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR0392572.1"
                     /translation="MTIRFEEKVSIENAQFVCQWSNSLGKSFQEQWMGPRIPFLLTLQ
                     ALEGVFSIFDEQEFVGLIQKIRLEDSNLHIGRFFINPQKQEQDLGSQALRKFVSLAFE
                     NEDIDSISLNVFEANQRAQNLYQKEGFEIVQMVEAPVRKYSRLKLE"
BASE COUNT        17653 a         9854 c        12639 g        16981 t
ORIGIN      
        1 tcattgagta ttaaattgag tttgaagtgg cttatttcaa agctttttgt atgtcttcaa
       61 tcatgagttt tgttgattca agtccgcctc cgcttagata ccagaggtct ggtgttagtt
      121 ggataatctt accattttta gcagcaggtg tttcagcgat aagggcattt tctaggacac
      181 cgtcgttgct agagttgtcc ccaccgatgg caagggtacg gttgatgaca aagaggatgt
      241 cagggttgat ttctttgaca ctttcaaagc tgacttcttg tccgtggcgt gagtcttcaa
      301 attttgtatc agttggtttg aatttcaagg tttggtacaa gaaagagaaa cgagatttgg
      361 caccaaaggc tgccattttt ccttcattaa ggaggatcgc aagggctttt ttgtcagagc
      421 tttcattttt agtagcgact tcttggatgc tcttgtctag cttggccaat tcttccttgg
      481 ctttctgtgt accagtttcg ccgaaggcac ttgctaagga ttcgatatta gccttggtag
      541 aagtccagta gtcgtccttg cttgcttgga agagaacggt tggggcgatt tctttgaatt
      601 tgtctacgaa tttttgtgta cgtggtgaag cgataatcaa atcaggctca agggcggcga
      661 tagcttctaa atcaggttct ttcatagaac caacattttt gacagttccc actaggtctt
      721 ttagataagt cggaacagtt tttgtaggca ttccgacgat atttttttca aatcctaaag
      781 cgcgaatagt atccgcagcg ccgaggtcaa aggtcacaat cttttcagga actttggaaa
      841 gtttgacctc ggccagtgaa cttttaatgg ttacctctgt tggagcagag ctactggtct
      901 ctgtctgact agtgcttgag tttgtactac atgcaccaag taggagcaag aagctggcca
      961 ctagggcagt gaaataaagt ttaagggatg ttttcataat ttctcctctt taaaatgtga
     1021 taacgattta gggagtctct tgatcttatt gactaagaga ctgaaggttc tctaacttga
     1081 gcttttatgt tactagctat agatacagat ctttttgtca ttgatatcag ctagcgtgat
     1141 gggaatctca taaagttgac tgagcaggtc agcctgcatg atttgatcgg ttcttccctt
     1201 gctaaagacc tggccgtcct tgaaggcgac aatttcatct gcatactgac tggctatgtt
     1261 gatatcgtgg aggacgatga taatggtctt gccgagttcc tccaccagtc gtcgaagaat
     1321 ctgcatcatg ctgacgcttt gcttgatatc gagattgttg agtggttcgt ccagcaagat
     1381 aaagtccgta tcctgggcca gtaccatagc gataaagacg cgctggagtt gcccccctga
     1441 caggctattg atgtagcggt cttttaagtt ggtcagttcc aaatagttca gagtttctcg
     1501 gattttttcc cagtcttctg atctaagtcg acctcggctg tagggaaaac gtccaaaact
     1561 gaccagttct tcaacagtca atttggcttg gtaattgatt ttctgtttta ggatggttag
     1621 ttcttgggcc agttcttgcg aattccagct ctcgatttca cgtcctttga tactgagaac
     1681 tccctgatct ttcttggtta gtctgctcat gatggagagg agagtcgatt ttccagcacc
     1741 atttggacca ataaaggctg tcagtttttg aggactgact tcaagcgaaa tgccttgcaa
     1801 aatatcctgt ttttgaatgg atttgtcaat gttttccagt ttcactgacg agccctccta
     1861 tatagtaaga taaagaataa gaagccaccc acactctcaa tgatcatact gatacgaatt
     1921 tccagtgcaa agactcgttc aatcaaggct tgccccaagg ttaagctaat aaatccaacc
     1981 agaatggcca ctataaagag taacttgtgc tgatagtctt tgacaatcag gtaggtgagg
     2041 ttggccagca taaagccgaa gaaggccata ggtcctacca aggaagtggc cgttgaggtc
     2101 aaaagcacga ttccccagag gagctctttc tgttcttttt caacatcgag tcccaatatc
     2161 tgagccgttt ctctttgcag gtgcaagaca tctagaacga ctgcttttcg aaagaaaaag
     2221 attgtcaaag cgaggatgat cagagaaccg atggctagga tggaagtgtt gagatgttga
     2281 aaggaggcaa aaagactatt ttgcagttta tcgtattcgt ttggatccat taggacttga
     2341 aggaaggtgc tgatatttcg aaagagactt ctgagcgcta gacagatcag caggatgaag
     2401 accaggtctt gcttcatcag tgtcttcaag taaccttgta aggcgagaaa gaagagggac
     2461 tggacaagaa gtaagactag gaattctaag ataggggatt tgccaagttg aagaaacttg
     2521 ctttcaaaaa ccagtagtag ggtttgtagt aggacgtaga aggattcaat tcccaaaata
     2581 ctaggcgtca ggaagcgatt ttccgtcagg gtttgaaaac taatggtcga aatcccagtc
     2641 gcgatggcta ccaagagata aacgatgatc ttttgggaac gcaacttcca agcaaaggct
     2701 gacaagtgag tgatgggcca aaagtagaga agacaagctc cgatggcaag aataatgaga
     2761 atccagaaga gcttggtatg tttgctttta gtctgcatct tttcgtcccc ctctccagag
     2821 aagtaggata aagacgagac taccgatgat tcctagcaag agactgacag acaactcata
     2881 gggcctaatc agaactcggg ataggatatc gcaagccaga actagattgg caccaaccag
     2941 tgcgaccatg agtttggttt gacttagatt atctccatag cgcttgcgaa caagattggg
     3001 aacgataact ccgagaaatg gtaggccacc cacggtaatc atggtgacgc ttgtcgttag
     3061 cgccaccaga aagagggcca gtttttcaag tagggagtag gaaatcccca aactctcgct
     3121 ggtttctttc cctagattca tgatggtgaa ggtttgggat aatttccaaa cggttatcag
     3181 gatgatgagg cctaagaaga gccactcata ctgatgggtc tgaatcatgg agaaggagcc
     3241 ctgggtccag gcagtcatac tctgaaccag attgaaacga taggcgataa cttctgtgac
     3301 tgagccgata atcccgctat agatgatccc aatcagaggc aacatccacc tttcctttac
     3361 agtaaaaatg gtcataaagg ctaggaagaa gagggtgaat acgatggatg aaacaaaagc
     3421 gaagagcatc ttttgggtca gactagccga tggaaagaca aaaaggctca gcaccattcc
     3481 cagtttggcg gcttcagtcg ttccaactgt actcggtgca gcaaactgat tttgggtaat
     3541 agtctgcatg agaaggcctg ccatactcat actagaggca gtcaggagaa tactgatagt
     3601 tcttgggaga cgggactctt gaaagaggag ccaggtctgc tggtcgaaat caaatagctt
     3661 tccccatgaa aaatcactgg tcccaatgct aatagagaga aagactagga gtagaagtaa
     3721 gccaattaaa taatgagaaa gtttcatacc ccgtcctttc atgtagattt ggtatcgaaa
     3781 gatatctgcg gatataaatg taacattatt tttctaatct gtcaataaaa tttctgacaa
     3841 tttaataaat acaacaagga gagagcaaca agactttctc ctttgttatc ctattctaaa
     3901 atgtttttac cttaatctga taaaataata tcttcgaggg agtagctagc cgtccaatca
     3961 agatattgtt tagcttttga agcatctgct aggacactgg ctgggtcact agcacgtcga
     4021 gcaacaatct cgtgtgggat tttttaattt agtaattctt cagcagtttt aaagatttct
     4081 ttgatagtat agcctttttt agttcctaag ttaaagattt gagaagaact gtcttcttga
     4141 aataggtagt tcattccttt aacatgagcc tatgcaaggt ccaagacata aatgtaatct
     4201 cgaatacatg aaccgtcacg tgtatcgtag tcatctccaa atatttttaa gctatcattt
     4261 tgtcccaatg cggtcttgtt gatatttgga atgatgtgag ttggattttt cacacgcaga
     4321 ccgtttgaag catccatttc agccccagca acattaaagt aacggaaaat aacatatttc
     4381 cagtcgtagc gattggccat ccagtaaatc attcgttcgc ccatcagttt tgtctctgca
     4441 taagggttga cagggtcgag cagggtatct tcagtcaccg gcttgtcaat acagttattt
     4501 ccatagagag aagcagtcga agagaacatg attttttgaa tgccaacttc agataagact
     4561 ttgagaactt ggttcatacc agcaacgttg gcagtgaagt atttacttgg attttcaata
     4621 ctttcgctca caacaatttc acctgcacaa tggaggacag catcaatctg attttcttct
     4681 aagtaagcct ttaaggcgct agcatcataa acatccagtt ctttaaagct agcacgacta
     4741 tccacagccg ctcgatttcc tgtggagaga ttatcgagga catgcacctt atagccagca
     4801 tttaaaagag ctttaacggt atgggagcca atgtagctag tcccacctgt aacaagaatt
     4861 gttttggtca tgattttttc cttttctagt tttgtactat agtaaattga aataagatat
     4921 gaacaactct attaggaaag tcaaattaat ttctagaaat gtttcagcag ctacagcgta
     4981 ctattccaaa ctcaaccaac tatatattta aagaaagaag aaagggaagt caactatttt
     5041 ctgtaaattt catgaaaaat ccaaacaact ttgatggtgt attgtttttt tgtttggaaa
     5101 taaatattcg agttaatttt ggaatgttta ctagattttg cactacatgc aagagaatac
     5161 tatccttttc taagatagag caggactaag atactaactt agaaatccac cttcccacta
     5221 tccttctcct ataaaaagtg gtaaaatgga tgaaagaaag aaggaactga aatgacaaca
     5281 ttattttcaa aaattaaaga agtaacagaa cttgctgcag tctcaggtca tgaagcgcct
     5341 gtccgtgctt atcttcgtga aaagttgaca ccgcatgtgg atgaagtggt gacagatggc
     5401 ttgggtggta tttttggtat caaacattca gaagctgtgg atgcaccgcg cgtcttggtc
     5461 gcttctcata tggacgaagt tggttttatg gtcagcgaaa tcaagccaga tggtaccttc
     5521 cgtgtcgtag aaatcggtgg ctggaacccc atggtggtta gcagccaacg tttcaaactc
     5581 ttgactcgtg atggtcatga aattcctgtg atttcaggtt ctgttcctcc gcatttgact
     5641 cgtggaaagg ggggaccaac catgccagcc attgccgata tcgtttttga tggtggtttt
     5701 gcggacaagg ctgaggcaga aagttttggc atccgtcctg gtgataccat cgtaccagat
     5761 agttctgcaa ttttgacagc caatgaaaaa aatatcatct caaaagcttg ggataaccgc
     5821 tacggtgtcc tcatggtaag cgagctagct gaagctttat caggtcaaaa actcggcaat
     5881 gaactctatc tgggttctaa cgtccaagaa gaagttggtc tgcgtggcgc tcatacctct
     5941 acaaccaagt ttgacccaga agtcttcctc gcagttgatt gctcaccagc aggtgatgtc
     6001 tacggtggtc aaggcaagat tggagatgga accttgattc gtttctatga tccaggtcac
     6061 ttgcttctcc cagggatgaa ggatttcctt ttgacaacgg ctgaagaagc tggtatcaag
     6121 taccaatact actgtggtaa aggcggaaca gatgcaggtg cagctcatct gaaaaatggt
     6181 ggtgtcccat caacaactat cggtgtctgc gctcgttata tccattctca ccaaaccctc
     6241 tatgcaatgg atgacttcct agaagcgcaa gctttcttac aagccttggt gaagaaattg
     6301 gatcgttcaa cggttgattt gattaaacat tattaaacca taagggaggt ggtagggatg
     6361 gtagaaccaa acctagaaag ccttataaaa gatctttaca atcatgctcg acatgatttg
     6421 agtgaagatt tagttgctgc tctcctagag actactaaaa aactgcctac tacaaatgag
     6481 caattgcagg cagttcgtct ctcaagcctg gtcaatcgtg aattgctcct aaatcccaaa
     6541 catccagcac ctgagttgct caacttggct cgctttgtca aaagagaaga agccaagtac
     6601 agaggaactg cgacttctgc gcttatgtat gaggaacttt ttaaaatgct ttgattccat
     6661 tgtggatcaa agcatttttt ataagaccta tctcgtgagc gttcaaatag tagtaacaag
     6721 gaatcatgag aagtcagccg agaccatagt agtgaagaaa cttctgtaat ggaagtggag
     6781 tgaagtgagg aatcgtcaaa cggtagggga taggctgttt gaagggtgct acgaaaaaga
     6841 tagggtaagg tgaaattata gcggaatgaa ataagatatg aacaaattga ttagggaaat
     6901 caaatgaatt tatagaaatc ttttagcagt catggcgtcc tattctagtt tcaaaatgct
     6961 ataaatacga acaaattgat tgggaaattc aaatcgcttt ctatcaatgt tttagaagat
     7021 acagtgccct agtccaactt caatatacta taaaagaaca gatggaagca attatgattt
     7081 acttctatct ttaaaataaa tgatctgata ggaaaaatgt gtcccctcat aaaaaatagg
     7141 atagtacgga tggaaggctt ttgtagactg gaggacgaag gaatttagaa actctcgtta
     7201 aaagttagtt gagccggagt atggtggtgt gaataattat caaaaattat ttccaaatcg
     7261 aaatagttga cagttagaac gatgagtgtt acaattattt tattcatttc gatatcgaaa
     7321 taaattggag gtgttatgaa agatagtcat ttgctagccc atcatattcg tttgttgaat
     7381 gggcggattt ttcaaaagtt actgagtcaa gatcctgagg ctctttatag gggtgaacag
     7441 ggcaagattt tagcggtttt atggaatagt gaaactggct gcgcaactgc gacagatatc
     7501 gcgcttgcga ctgggcttgc gaataatacg ctgacgacta tgataaaaaa gctagaggaa
     7561 caaaagcttg taattgttag tccgtgtgga aaagacaagc gtaagaagta tttagtttta
     7621 acggagttag gcaagttcca gaaagaagtg gggcatcgtg tcagtcagaa attggatact
     7681 atcttttaca aaggattttc agaggaagaa attcaccaat ttgaaggttt tcaagaaaga
     7741 attttggcaa atctgaaaga gaaggaaaat gaggtttaga atatgtcaca acaagtgaaa
     7801 aatgctcaca acctatacat ccatgccatt caagacggac gagttgctga ggctcaagcc
     7861 cagtctgtag gggataccta tatccaacat tcgacaggtg ttcctgacgg gaaagaagga
     7921 tttgcagcct tctttgcaga tttctttgag cgtcatccag agcgtcagat taagattgtc
     7981 cgcaccattg aggatggcaa tctggtcttt gttcatgttc atcaatatct gaatggtgga
     8041 gaagctcaat gggtgacgac ggatactttc cgtgcggatg agaatggttg tattgttgag
     8101 cattgggatg tcattgacta ctatcgaaca cctgaaaatg atcaactaga tcaaattttt
     8161 ggagattttg aaatcaagga tttggataag aaagcagaaa ataaaaagct ggttcgccgt
     8221 ttcttgacag aaattttcca aaatggggag ctagagcagt ggagtgatta tgtggcagac
     8281 gatttgattc agcataatca tgagattgga caaggaagtg ctgcttataa aaactatgtg
     8341 gctgaatata gtgtcacttt tgactttgtt ttccaactct taggacaagg aaactatgtg
     8401 gttagctatg gtcagactca gattgatggc gttgcttatg cccagtacga tatcttccgt
     8461 ttagagaacg ggaaaattgt ggagcattgg gataataagg aagtcatgcc taaggtagaa
     8521 gacttgacca atcgagggaa gttttaaatt gaggacaaag aatgattgaa tacaaaaatg
     8581 tagcactgcg ctacacagaa aaggatgtct tgagagatgt caacttacag attgaggatg
     8641 gggaatttat ggttttagta gggccttctg gatcaggtaa gacgaccatg ctcaagatga
     8701 ttaaccgtct tttggaacca actgatggaa atatttatat ggatgggaag cgcatcaaag
     8761 actatgatga gcgtgaactt cgtctttcta ctggttatgt tttacaggct attgctcttt
     8821 ttccaaatct aacagttgcg gaaaatattg ctctcattcc tgaaatgaag gggtggagca
     8881 aggaagaaat tacgaagaaa acagaagagc ttttggctaa ggttggttta ccagtagccg
     8941 agtatgggca tcgcttacct agtgaattat ctggtggaga acagcaacgg gtcggtattg
     9001 tccgagctat gattggtcag cccaagattt tcctcatgga tgaacccttt tcggccttgg
     9061 atgctatttc gagaaaacag ttgcaggttc tgacaaaaga attgcataaa gagtttggga
     9121 tgacaacgat ttttgtaacc catgatacgg atgaagcctt gaagttggcg gaccgtattg
     9181 ctgtcttgca ggatggagaa attcgccagg tagcgaatcc cgagacaatt ttaaaagtgc
     9241 ctgcaacaga ctttgtagca gacttgtttg gaggtagtgt tcatgactaa tttaattgca
     9301 acttttcagg atcgttttag tgattggttg acagctctat ctcaacattt gcagttgtca
     9361 cttttgacct tgttactagc tattttgctt gcgattccct tggctgtttt tcttcgctat
     9421 catgagaagc tggccgactg ggtcttgcag attgccggta ttttccagac catcccgtct
     9481 ctggccttgt tggggctctt tatccctttg atgggaattg ggaccttgcc ggctttgaca
     9541 gctctagtga tttatgcgat tttccctatt ttgcaaaata ctatcactgg gctgaaggga
     9601 attgatccga acctgcaaga ggctgggatt gcctttggga tgaccagatg ggaacgtctc
     9661 aagaaatttg aaattccact cgccatgcct gttatcatgt ctgggattcg gacggcagct
     9721 gttttgatta tcggtacggc aaccttggcg gccttgattg gagcaggggg actgggttcc
     9781 tttatcctgt tgggaattga ccgtaataat gccagtttga ttttgattgg ggcactttct
     9841 tctgcagtgc ttgctatcgc ctttaacttc ctactaaaag taatggaaaa agcaaaatta
     9901 cggacgattt tctcaggttt tgccttggtg gctttattac tgggtctgtc ttatagtcca
     9961 gctcttttgg ttcaaaaaga gaaggaaaac ttggttattg ctgggaaaat aggtccagaa
    10021 ccagaaattt tggccaatat gtataagttg ctgattgaag aaaataccag catgactgcg
    10081 actgttaaac cgaattttgg gaagacaagc ttcctttatg aagctctgaa aaaaggcgat
    10141 attgacatct atcctgaatt tactggtacg gtgactgaaa gtttgcttca accatcaccc
    10201 aaggtgagtc atgaaccaga acaggtttat caggtggcgc gtgatggcat tgctaagcag
    10261 gatcatctag cctatctcaa acccatgtct tatcaaaaca cctatgctgt agctgtttcg
    10321 aaaaagattg ctcaagaata tggcttgaag accatttcag acttgaaaaa agtggaaggg
    10381 cagttgaagg caggttttac actcgagttt aacgaccgtg aagatggaaa taagggcttg
    10441 caatcaatgt atggtctcaa tcttaatgta gcgaccatgg agccagccct tcgctatcag
    10501 gctattcagt caggtgatat tcaaattacg gacgcctatt cgactgatgc ggaattggag
    10561 cgttatgatt tacaggtctt ggaagatgac aagcaactct tcccacctta tcaaggggct
    10621 ccactcatga aagaagctct tctcaagaaa cacccagagt tggaaagagt tcttaataca
    10681 ttggctggta agattacaga aagccagatg agccagctca actaccaagt cggtgttgaa
    10741 ggcaagtcag caaagcaagt agccaaggag tttctccaag aacaaggttt gttgaagaaa
    10801 tgatgggaca gagactttaa acatactgaa ctcaacttcc ttaaacgact agataaaaga
    10861 atgctcagac aatttcgtct gggctttttt gatgtgagaa tgactgaatg tcacttaaaa
    10921 tggaaagaaa gagaaaattt tcatgatttt ctaaaatttt actgtaaaga cagttgacta
    10981 ttcataaaat aggtgtataa tattttgtga actacttaac aaataagggg tttcagctca
    11041 tgtcgactaa ggttagaaat cttgtgtata ggcagttcat tatctaatag agcgttgcgt
    11101 ccgaaagtct atccagacac ggctctttaa aaacaaaagg agaaatgatg catacttatt
    11161 tgcaaaagaa aattgaaaat atcaaaacaa ccctaggtga aatgtcaggt ggttaccgtc
    11221 gtatggttgc ggctatggct gatttaggat tttcaggaac tatgaaggct atctgggatg
    11281 acctctttgc ccatcgtagt tttgcccagt ggatttattt gctggtttta ggaagttttc
    11341 ctctctggct ggagttggtt tacgaacatc gtattgttga ctggattggg atgatttgta
    11401 gcttgacagg gattatctgt gtaatctttg tatcggaagg tcgagcaagt aattatcttt
    11461 ttggcttgat taactctgtt atttacctta ttttggccct acagaaaggc ttttatggtg
    11521 aggtgctgac gacactttac ttcacagtca tgcagccaat tggacttcta gtttggattt
    11581 atcaggcaca gtttaagaag gaaaagcagg agtttgtcgc gcgtaaactg gacggcaagg
    11641 gctggacaaa gtatctttcc attagtgtgc tttggtggtt ggcctttggc ttcatttatc
    11701 agtctattgg tgccaatcgt ccctatcgtg attcaatcac agatgcaacc aatggggtag
    11761 ggcaaatcct catgacagct gtttaccgtg aacagtggat attctgggcg gctaccaatg
    11821 tcttttcaat ctatctctgg tggggagaaa gcctgcaaat tcaagggaaa tatctaattt
    11881 atctcattaa cagtctagtt ggttggtatc aatggagcaa ggcagctaag cagaatactg
    11941 atttacttaa ctaggaaaag atgtttgaaa gtgctgtttt gagatttcga ttaaaacaga
    12001 tatagttgat aatcaaggat ttatagtatg aaaaagagga tcggcgggtc ctcttttgtt
    12061 gttgaaaaga taaaaaactc agtaacctag aaataagaca actgaagctt tactctatat
    12121 tcaattttta ggaatgagaa ggtctagata aaattggaca acttcctggt ctgtgaaatc
    12181 ttgacctttt ttgagccacc aggtcaatgt ttcgataaag ttagttacga caaaatgttg
    12241 gaggtaagaa gtaggtagac ttgggtgagt ttgcttcaaa tcagcagcca gcatgggata
    12301 gacgtggtgc tcaagctctc tctgtagttg acggaggaaa tagtcatttt tggaaaatag
    12361 cagactggcg atatggtctt ggtttttctg aaaatggaga aagaggtggg cgaggtagtc
    12421 ctcggttgaa atggcttgct ctctttcaaa aagatgatgg aagaggtagc ggcagagctg
    12481 atccagaaga agctctttac tctcatagtg acagtaaaag gtggatcgtc ccacatctgc
    12541 gagatcaatg atatcctgaa cagtagtggt ctcgtagtcc ttagcattca aaagttgtat
    12601 aaaagcttga tagatggctt ttttggtttt gctgatacgg cggtcaatgt tagtcatatg
    12661 gacacttgag gcaaattgtt cagaactgaa taaagctgac gttttgcttc tatcctttct
    12721 ttgagtttta gtggataatg ataatgaaca aggtgttcat aaatctatta taacaaagga
    12781 atgagaaata tgaaggcaaa atatgctgtt tgggtggctt ttttcttaaa tttgacttat
    12841 gccattgttg agtttattgc aggtggagta tttggttcta gcgctgttct tgctgactct
    12901 gtgcatgact tgggagatgt gattgcaatt ggaatatcag cttttctaga aacaatctcc
    12961 aatcgtgaag aagacaatca gtacaccttg ggctataagc ggtttagcct gctaggagcc
    13021 gtggtaacag ctgtgattct cgtaacaggc tctgttctag tcattttgga aaatgtcacg
    13081 aagattttgc atccgcaacc agtcaatgat gaggggattc tctggttagg aattattgcg
    13141 attactatca atctgttagc gagtctggtg gttggtaagg gaaagacaaa gaatgagtct
    13201 attctgagtc tgcattttct ggaagatacg ctagggtggg tagctgttat cctgatggcg
    13261 attgttcttc gatttacgga ctggtatatc ctagatcctc ttttgtccct tgtcatttct
    13321 ttctttattc tttcaaaagc ccttccacgt ttttggtcta cactcaagat tttcttggat
    13381 gctgtgccag aaggtcttga tatcaagcaa gtaaagagtg acctggagcg attggacaat
    13441 gtggccagcc ttaatcagct taatctctgg actatggatg ctttggaaaa aaatgccatt
    13501 gtccatgttt gtctaaaaga aatggaacat atggaaactt gtaaagagtc tattcgaatt
    13561 ttcctaaaag attgtggttt tcaaaatatt accattgaaa ttgatgctga cctagaaact
    13621 caccaaaccc ataagcgaaa ggtgtgtgac ttggaacgga gttatgagca tcaacattag
    13681 aaaaaagtga aaaatacttg ggtactatct tatttggaat agagtaattt ctttattatt
    13741 taaatatttc aaaaattggt aagagaagag cattgtataa actccagata tatgattgtt
    13801 aatgataaaa atttttcgat tagatacaaa atgcttgact tggagtcaac tcaaagttat
    13861 ataataagat aagtgagtta gaatagcgtg aattcagtga atgaaatgag aggaggttag
    13921 cgtgtgaata ttaaatctgc cagtgatttg ttgggaattt cagcggatac gattcggtat
    13981 tatgaacggg ttggtcttgt gccaccgatt actcgtactg ctactgggat tcgtgatttt
    14041 caagatcagg atatcgaagc gctggaattt attaagtgtt ttcgttcggc gggtgtctct
    14101 gtagatagtt tagttgacta tatgtcgctc taccaaaagg gagatgaaac gagagaggag
    14161 aggcttggta ttttagaaga ggaaaagcaa aaattagagg agcgcttgtc tcagctacag
    14221 acagctttaa atcgtttaaa tctcaaaatt aaactttata aggaaggaaa attttaaatg
    14281 aaatcagcag tatatacaaa ggcaggtcag gttggacttg cgtccgcaaa taatagaagc
    14341 ggatgatgtg attattcgtg tggttcgtgc gtgcgtttgt ggttcagatt tatggaggta
    14401 ccgtaatcca gaaacgaaag ctggacacaa aaatagtgga cacgaagcga ttgggattgt
    14461 tgaagaagct ggggaagcca ttacgacggt gaaaccaggt gattttgtga ttgtcccttt
    14521 tacacatgga tgtggtgagt gtgatgcctg tcttgctgga tttgacggtt cttgcgacaa
    14581 tcatattggc aataatttgg ggggtgattt tcaggcagaa tatattcgct tccactatgc
    14641 aaactgggcg ctggttaaaa tccctggtca accttctgac tatacagaag ggatgctcaa
    14701 gtcccttttg actcttgcag atgtcatgcc gacaggctat catgcggcgc gtgttgcaaa
    14761 tgttcaaaaa ggggacaagg ttgttgttat cggtgatggg gctgttggtc aatgtgctgt
    14821 catcgcggct aagatgcgtg gagcatcaca aattatcctt atgagccgtc atgaagaccg
    14881 tcaaaagatg gctatggagt caggtgcgac agctgttgtt gcagaacgtg gtcaagaagg
    14941 aattaccaag gtgcgtgaaa tcctcggtgg aggagcagat gcagcacttg aatgtgttgg
    15001 tacggaggct gctatagaac aggcgctagg tgttcttcat aatggagggc gtatgggctt
    15061 tgtaggagtc ccacactata ataatcgtgc tcttggttcg acatttatgc aaaatatctc
    15121 tgtagcaggt ggggcagctt ctgctacaac atacgataag caatttttac taaaagccgt
    15181 ccttgatggt gatatcaatc caggtcgcgt ctttacttca agttataaac tggaagatat
    15241 cgaccaagcc tataaagata tggatgaacg taagacaatt aagtctatga ttgtaatcga
    15301 ataaaaaacg aataggagtt ttagaactct attcgttttt tatgttatcc tattcttgat
    15361 ttagggtact ttctcttaat gtcagtctgg ttcccagcat ggtcaggcta gggattttcc
    15421 gaccgtggag gacttccttg ttaagaatat ccatacctgc tcgccccatt tcttcagtat
    15481 aaactgtgat gctggagagg ggaggataaa cctgcttggt caggctggtg tcgttaaagg
    15541 aaatgaggct gacacggtct ggtaggctga ttccagcttc ttggagcgca cgaagggcac
    15601 cgatggctaa actatcgctg gctgcgaaaa atgctggtgg gagttggtct cccaagttct
    15661 gaatggcttc cttcatcaag tcatagccag actgggcagt aaagtttcct tgaaagatca
    15721 gttcatcatg atagattcct tttgcttgac tgtagtttct gaaattttcc agccgcttat
    15781 cctcaatgat ttcttcttgg tcagttgttt cttcaaggcc tgttagaatc ccgatacggt
    15841 ccattccttg gctgaggaaa taatcgacaa cctgtttcat agcagtgtaa aaatccgtga
    15901 taatacaggt atgtcccagg gaaagtgtat cgctgtctag aaatacaaga ggcttttggt
    15961 attcttcaaa ggcagaaatc tgagctcggc taaattttcc gatgcagaga atcccaatca
    16021 cttcctcgct tagggtaaaa ggatggtcat taaaatagcg caagatatcg tagtccaact
    16081 cttgggctct tttttctatt cctaggcgaa tctggtagta gtagaggtcg tctagctccc
    16141 cttgttcgct gacccattga ataatggcaa tcttttgctt gggtttatgg gactcgcctg
    16201 tcttgaggtg cttggtgtag cccagctctt cagcaacggt taaaatacgg tgtctggttt
    16261 cttctgtaac agataggctc tggtcgcggt tgaggacacg ggatacggtc gcgatagaga
    16321 cagaggctag ctgtgcaatg tcttttaagg tagccataaa tcctccttga ttaggttagt
    16381 atatcatatt tttcttcttt ttactgatag tttactaaaa ttttagtaaa aaggattgac
    16441 cttgggaaat tccttggata caatagaaga aaacgattac acgttaagat ggcttaacgg
    16501 acagtcaaag gagaattcat atggcacaac atcttactac tgaagtcctt cgcaaagact
    16561 ttcttgctgt ttttggtcaa gaagcagacc aaaccttctt ttcaccaggt cgtattaatt
    16621 tgattggtga acacacagac tacaacggtg ggcacgtttt tcctgctgct atttccttgg
    16681 gaacttacgg tgcagctcgt aagcgtgacg accaagtctt gcgtttctac tcagctaact
    16741 ttgaggacaa gggcattatc gaagtgcctc tcgctgacct caagtttgaa aaagagcaca
    16801 actggaccaa ttatccaaaa ggggttcttc atttcttgca agaagctggg cacgtgattg
    16861 acaaaggttt tgatttttat gtttatggga atatcccaaa tggtgctggc ttgtcttctt
    16921 cagcatcctt ggagctcttg acaggagtcg tggcagagca tctctttgat ttaaaattag
    16981 agcgtctcga tttggttaaa atcggcaaac aaacagaaaa caactttatc ggagtcaact
    17041 ctggtatcat ggaccagttt gctattggta tgggggctga tcaacgtgct atttaccttg
    17101 ataccaacac cttagagtat gatttggtgc cacttgattt gaaggacaat gtcgttgtta
    17161 tcatgaacac caacaaacgc cgtgaattgg cggactctaa atacaatgaa cgtcgtgctg
    17221 agtgtgaaaa agcagtggaa gaattgcaag ttgccttgga tattcagacc ctgggtgaat
    17281 tggacgagtg ggccgttgac caatatagct atctaattaa agatgaaaat cgtttgaaac
    17341 gtgctcgcca tgctgtgctt gaaaaccaac gtacccttaa agctcaagca gcccttcaag
    17401 caggtgattt ggaaacattt ggtcgtttga tgaatgcgtc acacgtttct ctggagcatg
    17461 attatgaagt aactggtttg gaattagata cccttgttca cacagcttgg gcacaagaag
    17521 gagttctcgg tgctcgtatg acaggggctg gttttggtgg ctgtgccatt gccttggttc
    17581 aaaaagatac tgttgaggcc tttaaggaag ctgtaggcaa acactacgag gaagtagttg
    17641 gatacgctcc aagcttctat atcgctgaag ttgcaggtgg cactcgcgtc cttgactagt
    17701 caaaaggagg ctctatagtg accttagtag ataaatttgt aacacatgtc atttctgaaa
    17761 gttcatttga ggaaatggat cgaatctacc tgaccaatcg tgttttggca cgagtgggag
    17821 aaggtgtttt ggaagttgag accaatctgg ataaattgat tgacctcaag gaccagctag
    17881 ttgaggaagc cgttcgatta gagacgattg aggatagtca gactgcgcgt gaaatccttg
    17941 gtactgaact gatggacttg gtgactcctt gtccgagtca ggtcaatcgt gacttctggg
    18001 aagcctatgc ctactctcct gagcaagcga tagaggattt ttatcaactc agtcagaaaa
    18061 atgactacat caaactcaag gccattgcta aaaatatcgc ttatcgtgtt ccatctgatt
    18121 atggagaact tgaaattacc atcaatctct ctaagcctga aaaggatccg aaagagattg
    18181 cggtagccaa gttggtgcaa gctagtaatt atcctcagtg tcaactttgt ttagagaatg
    18241 agggttacca tggtcgggtc aaccacccag ctcgcagcaa ccaccggatt atccgttttg
    18301 aaatggttgg tcaggaatgg gggttccagt attcgcccta tgcttacttt aatgagcatt
    18361 gtatcttttt agatggccag catcgtccca tggccattag tcgtcagagt tttgaacgtc
    18421 tgttggctat cgtagagcag tttccaggat attttgctgg atctaatgcc gacctgccga
    18481 ttgtgggggg ctctattcta actcacgatc attatcaggg aggccgtcac gtatttccta
    18541 tggaattggc tcccttgcaa aagaccttcc gatttgctgg ttttgagcag gtcaaggctg
    18601 gaattatcaa gtggccaatg tctgtcctac gcttgacttc ggattccaaa gaggatttga
    18661 ttaacttagc tgataagatt ttccaggaat ggcgtcagta ttcagattct agtgtgcaga
    18721 ttttagcaga gacagacggg acaccgcatc acaccatcac accaatagcg cgtaagcgtg
    18781 atggacagtt tgagttggac ttggtcttgc gagacaatca gacttcagca gagcatcctg
    18841 atggcatcta tcatccccac aaggatgtcc aacatatcaa gaaggaaaat atcggcttga
    18901 ttgaggtcat gggcttggca atcttgccac cacgtctgaa agaagaagtg gagcaagtcg
    18961 ctagctatct tgtaggagaa gctgttacag ttgccgatta tcatcaggag tgggcagacc
    19021 aactcaaatc ccaacatcca gacctaacgg ataaagaaaa agcccttgca atcgtcaagg
    19081 actctgtggg tgctatcttt gtgcgtgtac ttgaggatgc aggagtctac aagcagacag
    19141 aacaagggca gacagccttt atgcgctttg tggaacaggt cggaatttca ctagactagg
    19201 agctttctcc ttgcacagtc ctataaaaag tagtatcata gtgtcgtttg aaatatcagg
    19261 aggaaacgat gaaagacttt cattttgacg ctatatctgc ctttgaaaat tacgaaattg
    19321 aaaaaatgag agatggtcac gttgtggtga cgaccaaagt agtgaactcg tcgctcaact
    19381 actatggcaa tgcccatggt ggctatctat tcacgctatg tgaccaaatc agtggtttgg
    19441 tggttatctc gctgggactt gatggggtga cactccaatc ctctatcaac taccttaagg
    19501 caggaaaact cgacgatgta ttgaccatta aaggagaatg tgtccatcaa ggtcgtacaa
    19561 cctgtgtgat ggatgtggat atcaccaatc aagagggcag aaatgtctgt aaagcaacct
    19621 ttaccatgtt tgtcacaggc caaaggtctg aggaaagacg ggtaaggata taaagaaagg
    19681 tgagtgggat aaatttatct cactcatttt taatttatga gatatgttag aaggaaatat
    19741 aaaagagagt ggtgaaatac aaatgtaata ggtacatata tgtggtatac tagttatagt
    19801 agattttaat tgcttatatc gagtgagttc tcatattagt gaggaatttt taaatggaat
    19861 tacactttaa tttagaatta gtagaaacct ataaaagtaa tagccaaaag gcacgtatct
    19921 taacggagga ttgggtttat cgtcagtctt attgccctaa ttgtgggaac aatcccttaa
    19981 atcattttga aaataatcgg cctgtagcag atttttactg taatcattgt agtgaggagt
    20041 ttgaactaaa gagcaaaaaa ggaaattttt catcaacaat caatgatggt gcttatgcaa
    20101 cgatgatgaa gcgtgtgcag gcagataata atcctaattt ctttttttta acttacacaa
    20161 aaaattttga ggtaaataac tttcttgtcc ttccgaagca atttgttaca ccgaaatcga
    20221 ttattcaaag aaaaccactt gcaccaactg ctagacgagc aggttggatt ggttgtaaca
    20281 ttgatttatc acaagtacct tctaaaggaa ggatatttct tgtgcaagat ggacaagtta
    20341 gagatccaga aaaagttaca aaagaattta agcaaggttt atttttaagg aagagctctc
    20401 tgtcatcaag aggttggaca atagaaattc taaattgtat agataagata gagggttcag
    20461 aatttaccct tgaagatatg tatcgttttg aaagtgacct aaaaaatatc tttgttaaga
    20521 acaatcatat caaagaaaag attaggcaac agcttcaaat attaagagac aaagaaataa
    20581 tagaatttaa aggtagagga aagtatcgga aattatgaaa acgaaacaac ttgttgcatc
    20641 agaagaggtg tatgatttct taaaagtcat ctggcctgat tatgaaactg aaagccgtta
    20701 cgataaccta agtttaatcg tctgtacctt atcagatccc gattgtgtga gatggttatc
    20761 tgaaaatatg aaatttggtg acgaaaaaca actagctttg atgaaggaaa aatatgggtg
    20821 ggaagtagga gataaattgc cagagtggct acatagctcc tatcatagat tattgttaat
    20881 aggtgaatta ttggaaagca atctaaaact gaaaaagtat acagtagaaa ttacagaaac
    20941 tttatcacgt ttagtaagta tagaggctga aaatccagat gaagccgaac gacttgtaag
    21001 agaaaagtat aagagttgtg aaattgttct tgatgcagat gattttcagg actatgacac
    21061 tagcatatat gaataggtag atgtttttat tttgtcacac aaaaaagagg ctcgcacctc
    21121 tttttcttat ttctttttat gatttaatac ggcattgagg acaatagcga gtaggctggc
    21181 tacgacgatt ccgtttgaga agaacatttg gaaggctgtc ggcatgctga caaagagatt
    21241 actgttgttg agaccgacac ctgcagcgat tgaaacagct gcgataagga agttgtgttc
    21301 attgttagca aagtcaactc gggcgaggat ttgcatccct tgaatagata caaaaccaaa
    21361 catcaccagc atggcaccgc cgaggacgga gcttggaatg atttgggcaa gggcaccaaa
    21421 cttaggaagc agtccaagga gaaccaggaa accagctgcg tagtagattg gcaggcgttt
    21481 tttgatgcct gacaatttaa ccaaaccaac gttttgtgaa aatccggtgt aagggaaggt
    21541 gttaaagatt cctccgagaa gtaccgccaa accttctgcg cggtaaccgt tgcgaaggcg
    21601 cgtgctgtcg attggatctt ttgtgatatc agacaaggct agataaacac cagttgactc
    21661 aaccatagac accgttgcga tgatacacat catgacaata gatgagattt caaaggttgg
    21721 catcccaaag tagagtggag ttgggacatg gacaagtgga gctaccgcaa caggagagaa
    21781 gtccaccaag cccatagtag cagcaatggc agttccaaca accagaccaa tcaaaataga
    21841 gatagacttg ataaatcctt tggtaaagat gttgatcaag aggataatca gaacagtaat
    21901 agctgaaagc aagagacttt gaccagttgg ctctggaacg ttatttccca tatttccaat
    21961 agcgacaggg atcaaggtta aaccaatcgt ggtaataaca gatcctgtta cgatagaggg
    22021 gaagagattg gccacttttg agaagatgcc tgaaacaaga accacgtaaa tcccagatgc
    22081 gataagggca ccaaacatag cgccactacc atggctttgc ccaatcataa tcaagggagc
    22141 gaccgactgg aatgcaactc caagaacgac tgggagtcca atcccaaagt atttgttgag
    22201 ttggagttgg aggaaggttg ccaccccaca catgaagata tctgtagaaa tcaggtaggt
    22261 caactgctca gctgaatagc caagggctgt cgcaatcatg atgggaacca ggatagatcc
    22321 tgagtacatg gctagtaagt gctgcaagcc aagaacggct gcttgcgagt gtttttcttg
    22381 agtttgcatt agagatctgc ctccttaaat acgacctgac cattttcaaa acgatccaaa
    22441 cgagcaagtg ataggacagg gtagcctgct ttttcaagca aatcacggcc atcttggaag
    22501 gatttctcaa tcacgatacc gatagcttgg actgtggcac cggcctgttc gatgatttga
    22561 atcaagcctt tagcagcttg gccattagca aggaaatcgt cgataatcaa aaccttgtcc
    22621 tctggtgaga ggaattttcc agcgatagaa acggtgctgg tcacctgctt ggtaaaggag
    22681 tagacttgag cagttaagat gccttcgttc atggtgatgt tcttagcttt tttggcgaaa
    22741 atcatgggaa cgtttaaggc ttcagctgta aaaacggctg gggcaatacc cgacgcttca
    22801 atggttacga ccttggtaat gccggcagca gcaaattttt ccgcaaaaac cttaccaatc
    22861 tctcgcatca agctaaagtc aacttggtgg gttaaaaagg aatctacctt gaggatgtta
    22921 tcacccaaga tatgcccatc cttgaggatg cgctcttcta ataatttcat aagacctcct
    22981 aaagtctaaa agctaattta cttgttgttt aaatgtttct atagtgatcc cttttgctaa
    23041 tactatatat ttgataaaac tattacgagc gaagcgagtc ttatcaaata tttcccgttg
    23101 tagtggtatc atagacaata atcttgttat tgtctatgac gggatttttg agagtaaaat
    23161 agttcgggga actattttag cctaagccta gaaatgaaag agctaggggc tcaaaaatta
    23221 gggatgaaat tccctggatt cctgaaatta ttcacaggat aatttcacct cccgtccgca
    23281 ctaattaagg gaaatattaa aaatattcaa aaaagaccta cttaatctct aagtaagtcc
    23341 cctaaataga catggcaaaa acggccatat ctcactgctg acttacttat tgttaggtgt
    23401 tccggcacct tgtagaaacg tcgtgccaat tcacgacata aacaagtaaa acgatattca
    23461 attttaaata ggcttgagcc aatgttttta ttttacacta aataacttta taaatcaact
    23521 attttgttag tgttttggtt taaaaaacga acaaacagaa gagggggtga acaaaaactc
    23581 cgttgtaagc taacatttat actaaatgaa aatcaaagag caaactagga agctatccac
    23641 aacctcaaat cactgttttg aggttgtgga tagaattgac agagtcagta tcatatacct
    23701 acggtaaggc gacgttgatg tggcttgaag agattttcga atagtattag aagatttttc
    23761 catcataaaa ggcatactat caagttttta gacacctgac aatatgcctt tttctaactt
    23821 taaagacttt tcccaatttt tattattcta ctcgctaaat cttaaaaaat agccatttgg
    23881 atccaaaact gcaaattcat gaggatagat atagggatca ctgacacgaa actttctctt
    23941 ggtcaaggga cgataaatag gatagtttgc cttcatcact ctttaataga gttttgaaac
    24001 atcctttatg ccaaaggaga gattgactcc acgaccaaag ggataggtca gttcagctag
    24061 ttgatccttt gttccctcct ctaacattag ttgacactct tcaagagaaa gagaaagttt
    24121 tcttctggac gttggtattc aatcctaaaa cccagtaaac cacagtagaa ggaccgggac
    24181 tgttcgatat tcgatacaag caactcggga atgaccgcat tgtagtccat atagaaaatc
    24241 cttacaagtc aatttccaag acaatcggtg tatggtcttg gcgagcacct gagtcaatca
    24301 tatcagattt agtgaccttg tcagcgatac ggttacttgt gagccagtag tcgattctcc
    24361 agcctgtatt gttgatttta gaagttttgc tgcgttgtgc ccaccaagtg tagcgttcag
    24421 gaacatcgcc atgaacatgg cggaaggtgt ctgtaaatcc agttgccaaa aggttggtaa
    24481 atccagcacg ttcctcgtca gtaaatccag gtgaacggcg gttgctagca ggatttgcaa
    24541 ggtcgatttc attgtgggct acgttgtagt caccggtcgc aaggactggt ttttctttgt
    24601 ctagtttagc caaatactca gcatatttgg catcccagac ttggcgttct tccaagcgtt
    24661 tgagaccgtc accagcgttt ggagtgtaaa cttgggttac gaaaaatgca tcaaattcta
    24721 gagtgatgat acgaccttcc aagtccatgg tagaaggggc accgatttct gggaagctga
    24781 tagtaggtgt aagttctttc ttataaagga acatggttcc agcatagcct ttacgggcag
    24841 gctcttggga agaacgccac gtgttttcgt agcctgggaa gagttcttct aaaatttcca
    24901 cgtgtttctt tgtaggtcct ttggcagaaa gcttggtttc ttggatagca atgatatcag
    24961 cattttcagc gaccaaggtt tgtaggactt cttgggacaa tttggcacga gctgagtcac
    25021 tagttagggc agcgtttagg gaatcaatat tccatgagat aagtttcata aagttacctt
    25081 tttcattcag attatagatt ttattatacc aaaaaaagat ctatttcccc aacgtatagt
    25141 ttgaaaaatt actctctttc gtttataatt aagaatgatt ttatgaaagg gagtgaaaat
    25201 acatgaaatt ctactcttat gactatgtac tcagccaaat cggtcagcaa aatggtatca
    25261 tggttggctt tgggattgtt ctattagctg tgacagtttt tttgctttta aggcatacca
    25321 tgataaaaag ggaaccgaat ttcgtgagtt ggtcatgatt tcagctctgg ccttatttag
    25381 ctctgctttt ggtcagcatc acgacttatc aaaacaatca agtttctaac aataaatttc
    25441 aaacttcact tcatttcatc gaggttgttt ccaaagattt gggagtagac aagtcagaag
    25501 tctatgttaa tacttccaca aacacagatg gcgcacttat caaggtggga gatcgctatt
    25561 atcgtgccct aaacggaagt gagccagaca agtacctgtt agagaaagtc gaattgtata
    25621 agacagacgc aattgaactg gtggatgtga ataaatgaca cttaattata tcgaaatttt
    25681 aatcaaactg gtcttgactc tcaaatggct caacaacaat gttcactttg tgaaacgttt
    25741 gattgatggt aagccaactc tccttatcaa aaatgggaat attgccccat aaacctgtcg
    25801 ttcagttggt ttgtctgcat cggatgtagc cctcaaactt cgtagccaag ggattttcca
    25861 gatgaagcaa gtcaaacgag ctgtgcaaga gcaaaatggg caactcatcg ttgtgcaaat
    25921 gggagatgaa aatcctaagt atccagttgt gactgacggt gtgattcaag tagatgtctt
    25981 ggaatcgatt ggtcgtagcg aagagtggtt gcttgataac ctcagtaaac aagggcatga
    26041 caatgtagcc aatatcttta ttgctgaata tgacaagggt gctgttacag tcgtaactta
    26101 tgaataagaa aaacctgggg tcttgtactc ttcgaaaatc tcttcaaacc gcgtcaacgt
    26161 cgccttgccg tatgtaggtt actgacttcg tcagttctat ctacaacctc aaagcagtgc
    26221 tttgagcagc ctgcggctag tttcctagtt tgctctttga ttttcattga gtattggcct
    26281 caggtttcca tttgcaatca gaaagggatt ttatgtccat tattcaaaaa ctttggtggt
    26341 ttttcaagtt agaaaaacgc cgttatctag tcggaattgt ggccctggtc ttggtttccg
    26401 tcctcaatct cattcctcct atggttatgg ggcgggttat tgatgccatc acatcggggc
    26461 aattaaccca gcaggacctc cttcttagcc tattttactt gctacttgca gcctttggta
    26521 tgtactattt gcgctatgtg tggcgtatgt atatccttgg gacctcttat tgcttgggac
    26581 agatcatgcg gtctcgcttg tttaagcatt tcacaaaaat gtcgtcagcc ttttatcaaa
    26641 cctatcggac gggtgatctg atggcacacg caaccaatga tatcaatgcc ttgactcgtt
    26701 tagcaggtgg cggtgtcatg tctgcggtgg atgcctctat cacggctctg gtgactttgt
    26761 tgaccatgct ctttagcatc tcatggcaga tgactcttgt tgccattctc cccctacctt
    26821 tcatggccta tgcgactagt cgcctaggga gaaagactca taaggccttt ggcgaatccc
    26881 aaactgcttt ttctgaactc aataacaagg tacaggagtc cgtatcaggt atcaaagtga
    26941 ccaagtcttt cggttatcag gcagacgagt tgaagtcttt tcaggcagtc aatgaattaa
    27001 ccttccaaaa gaacctgcaa accatgaaat atgatagtct ctttgaccct atggttctct
    27061 tgtttgttgg ttcgtcctat gttttaacgc ttttggttgg ctccttgatg gttcaggaag
    27121 ggcagattac agttgggaat ctagtcacct ttatcagcta tttggatatg ctggtctggc
    27181 ctcttctggc catcggtttc ctctttaata ctactcagcg agggaaggtt tcttaccagc
    27241 ggattgaaaa tcttttgtct caggaatctc ctgtacaaga ccctgagttt cctctggatg
    27301 gtattgaaaa tgggcgtttg gagtatgcca ttgacagctt tgcttttgaa aatgaggaaa
    27361 cactgacgga tattcacttt agtttggcaa aagggcaaac cctgggcttg gttgggcaga
    27421 caggctctgg gaaaacgtcc ttaatcaagc tcctcttgcg tgaatacgat gtggataagg
    27481 gtgccattta tctaaacggt cacgatattc gggactatcg tctgacagac cttcgcagtc
    27541 tcatgggcta tgttcctcag gaccagtttc tctttgcgac ttcaatccta gacaatatcc
    27601 gctttggcaa tcctaacttg cccctttcag cggtcgagga agctactaag ctagcccgag
    27661 tttaccaaga tattgtagac atgcctcaag gatttgatac gctgattggt gaaaaaggag
    27721 tcagtctttc tggtggtcaa aagcaacggt tggctatgag tcgggctatg attttagacc
    27781 ctgatatctt gattttggat gattccttat ccgccgtaga tgccaagaca gagtatgcga
    27841 ttatcgacaa cctcaaggag acgcgaaagg acaagacaac cattatcact gcccatcgcc
    27901 tgagtgcagt tgtccatgca gatttgattt tagtcctgca aaatggtcaa attatcgaac
    27961 gaggcaggca cgaagacttg ctagctttgg atggctggta tgcccaaacc taccagtctc
    28021 agcagctgga aatgaaggga gaagaagatg cagaataaac aagaacaatg gactgtattg
    28081 aagcgcttga tgtcctatct caagccttat agactcctga cctttttggc actcagcttt
    28141 ctcctagcga cgacggtcat taaaagtgtc atacccctcg tggcttccca ctttatcgac
    28201 cagtatctca gcaatcttaa ccaactagcc gttaccgttt tgctggtcta ctatggtctc
    28261 tacatcctac aaactgtagt tcagtatgtc ggcaatcttc tctttgcgcg cgtgtcttac
    28321 agtattgtta gggatattcg tcgggatgcc tttgccaata tggaaaagtt gggcatgtct
    28381 tattttgaca agacgccagc aggttctatc gtttctcgtt tgaccaacga taccgagacg
    28441 attagtgata tgttttctgg gattttatcc agctttatct cagcagtttt tatctttctg
    28501 acaacccttt ataccatgtt ggtgctggat tttcgtttga cggctttagt cttgctcttt
    28561 cttcctttga ttttcctttt ggtcaatctc tatcgaaaaa agtcagtgaa aatcatcgag
    28621 aaaaccagaa gtctcttgtc agatatcaat agtaagctgg cagagaatat cgagggaatc
    28681 aggattattc aggcctttaa tcaagagaag cgcctgcagg cagaatttga tgaaatcaac
    28741 caagaacact tggtctacgc caaccgttct gtagccttgg atgccctctt tttgagacct
    28801 gccatgagtt tgctgaaact tctaggctat gcagtcttga tggcctactt tggctaccgt
    28861 ggtttttcta tcgggataac ggtcgggacc atgtatgcct ttatccagta catcaaccgc
    28921 ctttttgacc ccttgattga ggtgacgcaa aacttttcaa ctctgcaaac ggctatggtt
    28981 tctgcaggtc gtgtctttgc cctgatagac gagaggacct atgaacctct tcaagaaaat
    29041 gggcaagcca aagtccaaga aggcaatatc cgttttgaac atgtgtgttt ctcatatgac
    29101 ggtaaacatc cgattctgga tgacatttct ttctctgtta ataagggtga aaccattgcc
    29161 tttgtaggtc atacaggttc agggaaatcg tctattatca atgtcctcat gcgcttttat
    29221 gaattccagt cagggagagt tctcttggat gatgtggata tcagggattt cagtcaagaa
    29281 gagctgagaa aaaacatcgg tttggtcttg caggaaccct tcctctatca tggaactatt
    29341 aagtccaata tcgccatgta ccaagaaatc agtgatgagc aggttcaggc tgcggcagcc
    29401 tttgtggatg cagattcctt tattcaagaa cttcctcagg ggtacgactc ccctgtttcc
    29461 gagcgtggtt cgagcttctc tactgggcag cgccagcttc ttgcctttgc tagaacagtc
    29521 gccagccagc ctaaaatcct gattttggat gaagcgacag ccaatattga ctctgaaaca
    29581 gaaagtttgg ttcaagcttc tctggcgaag atgagacagg gccgaacaac tattgctatc
    29641 gctcaccgcc tttctactat tcaagacgcc aactgcatct atgtcttgga taagggacgc
    29701 attatcgaga gtggaaccca tgaggaactc ttggctctgg gaggaactta tcacaagatg
    29761 tatagtttgc aggcaggggc catggccgat actctttgaa aatctcttta aaccatgtca
    29821 gctttatctg caatctcaaa gctgtacttt gattttcatt gagtactaga aggaaatcct
    29881 tcaaattaca gatttctttc accgcctttt ccattttgtg gtataatgaa aaatgttgac
    29941 aaatagtata ataaaaacaa aggagaacag catgctgaaa tgggaagact tgcctgtgga
    30001 aatgaaatca agcgaggttg agtcttacta ccagcttgtc tctaaaagga agggttcgct
    30061 gattttcaag cgttgcttgg actgggtttt ggccttggtc ttactggttc taacctctcc
    30121 catctttctc atcttgagca tttggatcaa gttggatagc aaggggccag tgatttacaa
    30181 gcaagagcgt gtgacccagt acaaccgtcg gttcaagatt tggaagttcc gtaccatggt
    30241 gacggatgcg gataaaaaag gaagtctggt gacttctgct aacgatagcc gtattaccaa
    30301 ggttggaaat ttcatccgac gtgtccgttt ggacgaactg cctcagttgg tcaatgtcct
    30361 taaaggtgag atgtcctttg tcggtacacg acctgaagtg ccacgttata cagagcagta
    30421 tagccctgaa atgatggcaa ccttgctctt gcaagcagga attacctctc cagccagcat
    30481 caactacaag gatgaggaca ccatcatcag tcaaatgacg gagaaaggtc tgtcagttga
    30541 tcaggcctat gtggagcatg ttcttcctga aaagatgcgc tataacctcg cctatctccg
    30601 agagtttagt ttctttgggg acatcaaaat catgtttcaa accgtgtttg aggtactaaa
    30661 ataaagtagt cataagaaaa tgagtacaga taaaaggagc aaatcaatgc caaattacaa
    30721 tattccattt tcaccgcctg atatcacaga agcagaaatt gctgaagtag cggataccct
    30781 gcgttctggt tggatcacaa caggtcctaa aacaaaagaa ctggagcgcc gcttgtctct
    30841 ttacacacag acacctaaga ctgtttgtct caactctgcg acagccgctc tggagttgat
    30901 tttacgcgtt ttggaagtgg gacctggtga tgaagtcatc gttccagcca tgacctatac
    30961 ggcttcatgt agtgtcatta cgcacgtggg agcaacccct gtcatggtgg atatccaagc
    31021 agatacgttt gagatggact atgacctgct tgagcaagct atcactgaga aaactaaggt
    31081 gattatccca gtagagctcg cagggattgt ttgcgattat gaccgtttgt tccaagtcgt
    31141 ggagaaaaaa cgtgacttct ttaccgcttc aagcaagtgg caaaaggcct ttaaccgtat
    31201 tgtcattgtc tctgatagtg cccacgcttt gggatctact tataaaggac aaccttctgg
    31261 ttctatcgct gactttactt ccttctcatt ccatgccgtt aagaacttta caacggcaga
    31321 aggtggaagt gcgacttgga aagccaatcc agtgattgat gacgaagaga tgtacaagga
    31381 attccaaatc ctttcccttc acgggcaaac taaggatgct cttgccaaga tgcaactggg
    31441 gtcatgggaa tacgatatcg ttacaccagc ctataagtgc aacatgaccg atatcatggc
    31501 ttcacttggt ttggtacaat tggaccgcta tccaagtttg ttgcaacgcc gtaaggacat
    31561 tgtggaccgc tatgatagtg gttttgcagg ttctcgcatc catcctttgg cacacaagac
    31621 tgaaactgtc gaatcttcac gccacctcta catcacccgt gtagaaggag caagcctaga
    31681 agaacgcaac ctcatcatcc aagaattggc taaagcagga attgcaagta atgttcacta
    31741 caaaccgctt cctctcttga cagcctataa gaatcttgga tttgatatga cgaactatcc
    31801 taaggcctat gccttctttg agaatgaaat taccctccct cttcatacta aattaagcga
    31861 tgaagaagta gactatatca ttgagacttt caaaacagtt tctgaaaaag tgctaacttt
    31921 atcaaaaaaa tgacaaacta cagtcaagcg aaagtgatcc tgtccttaaa aaatctaatt
    31981 gagtgtaaaa actgttgttt tcaattgata atagtttaca cctgtagttg aggctccttt
    32041 ctcctcagag agagaatttt tataggattt tcctttcttg tgggagtccc gtggtttgaa
    32101 ataagatgtg agcaatttgg tgtagcattt agaatcctta ctagacatca tttagaaaat
    32161 ctagtgtctt gttctagttt tcaattcacc ctattttttg aaagacgtga gtttccatga
    32221 gtgagattgt ggaaactcgc gtcttttttt gttttcagaa tattgttcaa agttttgtgc
    32281 ctgtctttca tgttctagtc attcttttgc atgatagaat ttatagcata ttgatattat
    32341 aataatacaa atattctata cgtttagtga tgcttgctat acatcattag atctcccgcg
    32401 agacaatcta taaaacactt gtctacgatt acctatatgc cctattccag tattttagaa
    32461 gcactgcatc tatttttatc gaggttaaat ctagctttta tagaaggtct atttaagaaa
    32521 tatattgtag tgttttagtt tcaatccgcc atatgagcga tattcaggta aatatcccta
    32581 gcgaatgctt gtatgacaag atatttgttc tttcatttat aatttacaac atatcaacaa
    32641 atttaaatat agtaaatggg atattttata ttcaagctaa gaaagatagc atcacttttg
    32701 aatggaaggc taaagagcaa actaggaagt tggccataga tagctcaaaa ccctgctttg
    32761 aggttgtaga tataataaaa tgaaataaga ataggacaaa tcgatcggga cagtcaaatc
    32821 gatttctaac aatgttttag aagtagaggt gtactattat agtttcagtc tactatagaa
    32881 ctgaccaagt cagtaaccta gacttagggc aaggcggcac tgacctagtt tgaagagatt
    32941 tccgaagagt ataaatttta atattttctt gtgttattcc ttgacaattc aatttggaaa
    33001 atatatgata aagataatga cagcggtgtc attctatcta ttttaagaaa agtaataatc
    33061 aattgttaaa aatagtaaaa aaattggagg ttctgatgaa atattttgtt cctaatgagg
    33121 tattcagtat tcgtaaatta aaggtgggga cttgctcggt actattggca atttcaattt
    33181 tgggaagcca aggtatttta tcggatgaag ttgttactag ttcttcaccg atggctacaa
    33241 aagagtcttc taatgcaatt actaatgatt tagataattc accaactgtt aatcagaatc
    33301 gttctgctga aatgattgcc tctaattcaa ccactaatgg tttagataat tcgttaagtg
    33361 ttaatagtat cagctctaat ggtactattc gttccaattc acaattagac aacagaacag
    33421 ttgaatctac agtaacatct actaatgaaa ataagagtta taaggaagat gttataagtg
    33481 acagaattat caaaaaagaa tttgaagata ctgctttaag tgtaaaagat tatggtgcag
    33541 taggtgatgg gattcatgat gatcgacaag caattcaaga tgcaatagat gctgcagctc
    33601 aagggctagg tggaggaaat gtatattttc ctgaaggaac ttatttagta aaagaaattg
    33661 tttttttaaa aagtcataca cacttagaat tgaatgagaa agctacaatt ctaaatggta
    33721 taaatattaa gaatcaccct tccattgttt ttatgacagg tttatttacg gatgatggtg
    33781 cgcaagtaga atggggccca acagaagata ttagttattc tggtggtacg attgatatga
    33841 acggtgcttt gaatgaagaa ggaactaaag caaaaaatct accacttata aattcttcag
    33901 gtgcatttgc tattgggaat tcaaataacg taactataaa aaatgtaaca ttcaaggata
    33961 gttatcaagg gcatgctatt caaattgcag gttcgaaaaa tgtattagtt gataattctc
    34021 gttttcttgg gcaagcctta cccaaaacga tgaaggatgg gcaaatcata agtaaggaga
    34081 gcattcagat tgaaccatta actagaaaag gttttcctta tgccttgaat gatgatggga
    34141 aaaaatctga aaatgtgact attcaaaatt cctattttgg caaaagtgat aaatctgggg
    34201 aattagtaac agcaattggc acacactatc aaacattgtc gacacagaac ccctctaata
    34261 ttaaaatttt aaataatcat tttgataaca tgatgtatgc aggtgtacgt tttacaggat
    34321 tcactgatgt attaatcaaa ggaaatcgct ttgataagaa agttaaagga gagagtgtac
    34381 attatcgaga aagcggagca gctttagtaa atgcttatag ctataaaaac actaaagacc
    34441 tattagattt aaataaacag gtggttatcg ccgaaaatat atttaatatt gccgatccta
    34501 aaacaaaagc gatacgagtt gcaaaagata gtgcagaata tttaggaaaa gtatcagata
    34561 ttactgtaac aaaaaatgta attaataata attctaagga aacagaacaa ccaaatattg
    34621 aattattacg agttagtgat aatttagtag tgtcagagaa tagtatattc ggtggtaaag
    34681 aaggaattgt tattgaggat tcaaagggta aaataaccgt tttaaataac caattttata
    34741 atttatccgg taagtatata tcattcatca aatctaatgc aaatgggaaa gaacctgtta
    34801 tacgtgatag cgatggtaat ttcaatattg taacggagaa tgggctttac aaaattgtaa
    34861 caaataattt aagtgataaa aacgaaaaag aaaaaaacaa agaggaaaaa caatctaatt
    34921 caaataatgt aattgatagt aaccagaaga acggagagtt taactcaagt aaagataata
    34981 gacaaatgaa tgacaagatc gacaataaac aagataataa gacagaagaa gtaaactata
    35041 aaatagttgg agatggcaga gaaactgaaa atcatattaa taaatctaaa gaaatagtag
    35101 atgtaaaaca aaaattacca aagactggtt cgaacaagat tatggaacta ttcttaacag
    35161 tgacaggaat tggtttactt ttgacactaa aagggttgaa gtattatggt aaagataaat
    35221 aaaatttgtt cgatacaagg aagttccgta gaaaatgagg atattgtagg ttcacaaaat
    35281 cagtattttt ggattattgg tggagctaca gatttatata attctaaaga ggagataggt
    35341 tattcagtct cagaagttgt acatatttta tcagaaagtt tgtcggttaa ttgtaaagaa
    35401 tcaaaaactc ttaaacaaat atttgaaact gctttactcg aggttaaaga tgaaatcggt
    35461 ttaaactcat atgaattaac agagtataat aaaatgaaat aataatagga caaatcaatc
    35521 aggacagtca aatcgatttc taacaatgtt ttagaagtag aggtgtacta ttctagtttc
    35581 aatatactat attatcgctt accaacattt gcttttatat ttgctaaact ttcagaaaaa
    35641 aagttggagt atatgatgct aggtgactgc gtcatgttag taaacgaaat ggaaataacg
    35701 gatcatagag tagataactt atttgaaaaa gggaaaaatg agataaaaga ttcaattggt
    35761 acaaatagtg ttttaaataa aaaaattatt ttacaaaaaa tcagaaaatt atctaatcaa
    35821 ccgagtgggt actggatagg ttcgttggat gagagatttt tagaccatgc tattattaat
    35881 caaatagatg ttactagtga acaaattgtt ttaatgagcg atggctttta tgaattctat
    35941 caaaataatc aaaataaaac ttttgaagag ttaattaaga tgagatttaa ttcttctgct
    36001 attgatccaa tctatggaaa gaaggatgat gcaagtattc tagtcattga tgtttgatat
    36061 attgtttaaa atattaattg ttactattga actttgttaa gaagaggtac ctaaatgcta
    36121 aggttatatt tagaaaatga aattatagaa ttatcaaata atttagagac catttgggta
    36181 tctgtgcttg ataaatatga gaagttattt gaatatttat caaatgaaga acgaatagaa
    36241 ttgattaaag aagatttaat cataaatgag tcagttctaa atattgataa aaaaggatat
    36301 gagttaattt gtttacaata tcctgtttca tatgacttaa gaagaattat tagtgtaata
    36361 aaaatatcaa ctgacattga acgtattggg gatagaattg ttgaaatttt aaaaaatcta
    36421 cagattcttc aaaataatga aattttgaag aaaattattt cagaaataaa aatacttcat
    36481 gaagttatcg gactgcatat gaatagggct atatcttgtt atagagagga acaatctgga
    36541 tgtttagata tggttgttat acaaaaacag aatgagatag aagagcttag tataaatatg
    36601 gaaaagaaaa taatgaatta catatttgaa gatgatggga acgtttctga agtaattagt
    36661 gctttagata ttattcatca ccttgataaa attgctcata ctacgcaagc aatttataaa
    36721 tggataatgt atagaaaata tgggaacata aattagaaag aaaaatatat gaaaacaatt
    36781 attgataatt ttgttgatag agtaattgaa tacggaatgt ataatgaaat tgacaaaata
    36841 tatgtgaaaa atagagtact agcgttaata ggtgaggagg gaattgatcg catttccgat
    36901 gaaaatgacc tgaaacaaat aaaagattac ttagtggaaa tcgccttaaa aaacggtaaa
    36961 attaaagatt taatcgagga aaaggaatgt ttaggagcag agttaatgaa tttcatagtt
    37021 cctttaccta gtcgattaaa tgatattttt tggagttcat atgatatatc acctcaagaa
    37081 gcagttgaag agttttataa gttaagtaaa gatagtgatt atattaaaac ttctgctatt
    37141 gctaagaata ttgagtttcg agcatcaact aaatacggag agctagagat tacgataaat
    37201 ttgtcaaaac ccgaaaaaga tccaaaaaca attgctgctg aaaaattagt aaaagcaact
    37261 aattatccca aatgtttact atgtatggaa aatgaaggat atcaggggcg aataaattat
    37321 ccagcacgtt cgaatcatag aattattcgg ttgaaacttg gtgacgaagt atggggattc
    37381 cagtattctc cctactcata ctttaatgag catgcgatat ttttgaatag tcaacatgta
    37441 ccaatggcta ttacctctaa aacatttgaa caattattgg agattgttga tattttgcca
    37501 ggatattttg ctggttcaaa ttctgatctt cctatctcag gaggctccat tcttagtcat
    37561 aaccactacc agggagggaa acatattttc ccaatggaaa aagcaaaatt tgagagtgaa
    37621 ttttgtttta aagactttga ggatgttaat gctggtattg taaaatggcc aatgtcagta
    37681 attaggttac aaagtgaaaa taaaaatcgc ttgttagatt tagctactaa aattctaaat
    37741 aagtggagag aatattcaga tttagaagta gacatcattg ctatgactga agatgtccca
    37801 caccatacgg tgactcctat tgctcgtaaa gtggacggga gatatgaatt agatattgtt
    37861 ctaagagata atcatactac tgaacagtac ccagatggtg ttttccatcc tcatcaagat
    37921 gtacaacata ttaaaaagga aaatatcggg ttaatcgaag tgatgggact tgcgatatta
    37981 ccacctcgtt tgaaaccaga gttagaagaa gtgggaaaat atcttttagg agaggaaaac
    38041 gcaattgcgg attatcattt agaatgggcc gaccaattga aagaaaaata tcctcgcatt
    38101 aataaagaag aggttaataa cgtagttcaa cacgaagcag gacaagtgtt tgcgagagtt
    38161 ctggaagatg caggagttta taagaataca ccgtctgggc atgaagcgtt tatgagattt
    38221 gttaagtcgg ttggaattaa ttaggaggaa acccaaatgg caatattggt aacaggcgga
    38281 gctggttata ttggtagcca taccgtagta gaattactaa atttaggaaa ggaagtcatc
    38341 attgtcgaca acctttcgaa ctctagcatc ttggtgctag accgtattga agcaattaca
    38401 ggaatacgtc ccgtgtttta cgaattagat gtttgtgata aacaagcatt gagaaaggta
    38461 tttgaacaag aatcgattga tgctgcaatt cattttgcag gttataaagc tgtcggagaa
    38521 tccgtgcaaa agcctgtgat gtactacaaa aataatatta tgagtacatt ggcacttgtt
    38581 gaagtgatgt cagaatttaa tgttaaaaag attgtctttt cttcaagtgc gactgtatat
    38641 ggaattaaca atcagtcacc tctaattgag acgatgcaaa caagtgcgac aaatccttat
    38701 gggtatacga aagtgatgct tgagcaaatt ttaaaagatg ttcatgtggc agattcagaa
    38761 tggagtattg cgttgcttcg ttatttcaat ccaattggtg ctcatgagtc tggtttgatt
    38821 ggggaagatc cctcaggaat tcctaacaac ttgatgcctt atattgcaca agtagcggta
    38881 ggtaagctat cagagctaag tgtgttcgga aatgattatg atacgcttga tggtactggt
    38941 gtgcgtgatt atatccatgt agtagattta gcaataggac atataaaagc tttagaaaaa
    39001 gtatctgaaa aaacagatgt ttatatctat aacctaggct cgggagaagg cactagtgta
    39061 ttacaacttg taaatacatt tgaaagtgtt aataagatcc ctattcctta taaaatagtt
    39121 ccaagacgtt caggagacgt tgcaacttgt tatgcaaatg cagacaaagc atataaggaa
    39181 ttaaattgga ggacaacaaa atcgattgaa gacatgtgta gagatacatg gaattggcaa
    39241 tcaaaaaatc ccaatggcta taattgatga tactgtctat atgagtgctg tattttgaaa
    39301 aaattactta accttttaat gaaatgcata tttaatgaaa gataaattta aaaaaatgtt
    39361 tgcaagtgct tgacaaagga aacggtttca ttgtataatg taaacatgat gacaccgatg
    39421 tcaaatataa aaaagaaggt ctttatatga aaaacttaac aaaaattaag ttcaaagaga
    39481 atggggaatt taatcatttc cctgggaata cagttgtagc aaatctttat actaaacaag
    39541 atttgatgga agttgttgat attattcaat cacgttatag agaattacca tttatcgata
    39601 agtttacttt aactccaagg aattctattc acatgactgt aattgaattg ttgtgccatg
    39661 aaaatcgtga aacggagttt tggagcagta atcttcctct agatacacct ttacaggaaa
    39721 tacatgatta ctttgctaaa caacttgaaa tttttccatt gttggatgaa gaaattcata
    39781 tgcgtataac tgaaatggga aaacaaaaca tactagttga acctgcagat gaagcttctg
    39841 caaagagatt agaagaaatt cgtacttatg tctcagaaaa agcaggtgtt tgtttcccta
    39901 atcatgatag atatcaattc catatttcaa ttgggtatct tcggattcct ctaaccgaag
    39961 aggaggaaga agagtttact aaagtcagag cagaattaac tgaaatttta ttagagaaga
    40021 ttccaactat tactgtaaac cgtattgact atactgtatt tgaagatatg agacaatttg
    40081 ttccatatca cgaaaaattt aaataaaata ataaaaaagg agaacttatc atgaaaaaaa
    40141 tgaaagtttg gtctactgta cttgcaacgg gagttgctct tactacactt gctgcttgct
    40201 ctggaggttc aaattctacg actgcttctt catctgaaga aaaagctgat aaaagtcaag
    40261 aattagttat ctattcgaac tcagtctcaa atggtcgtgg tgattggtta actgctaaag
    40321 caaaagaagc tggttttaat ataaaaatgg ttgatatcgc tggcgctcaa ttagcagacc
    40381 gtgttattgc tgagaagaat aatgcagttg cagatatggt atttggaatt ggtgctgttg
    40441 attcaaataa aattagagat caaaaattac tagtacagta caagcctaaa tggttagata
    40501 aaattgatca atctttatca gataaagata attattataa tcctgtgatt gttcaaccat
    40561 tagttttaat tggggcgcct gatgtaaaag aaatgcttaa agattggact gaattaggta
    40621 gtaagtataa aggtaaatat tcaatttatg gtcttcaagg tggtacagga cgggcaattc
    40681 tagcaagtat cttagttcgt taccttgatg aaaaaggaga tttaggcgta tcagaaaaag
    40741 gatgggaagt tgcaaaagaa tactttgcaa atgcctatac tcttcaaaaa ggtgaaagct
    40801 cagttgttaa agcgttagat aaagaaagcc caattcaata cggtatgatc tggggttctg
    40861 gagcgttaat tggacaaaaa gaacaaaatg ttgaattcaa agttatgact cctgagattg
    40921 gtgtaccatt tgtaactgaa caaactatgg ttttaagcac tagtaaaaaa caagcgttag
    40981 ctaaagaatt tattgattgg tttggtcaat cagaaattca agtagaatat agtaaaaaat
    41041 ttggatctat tcctgccaat aaagatgccc taaaagagtt acctgaagat acgaaaaaat
    41101 ttgttgatca agtgaaacca caaaatattg actgggaagc tgttggaaag catttggatg
    41161 aatgggtaga aaaagctgaa ttagaatacg taaaataaga aataagagtt attttttatg
    41221 tccaagtctc tctattattt ctaaatttaa ggaagaaata aagagaggct tttggtttta
    41281 gtaatagagg gagttagtga gatgattaaa tttgataata ttcaaattaa atatggtgat
    41341 tttgttgcaa ttgataatct gaatttagat atacatgaag gggaattctt tacatttctt
    41401 gggccttcag gatgtggtaa atcaactact ttgagagcat tggtaggttt tttagatcca
    41461 tcatcaggaa gtattgaagt taatggaaca gatgtcactc atttggaacc tgaaaagcgt
    41521 ggaattggta ttgtatttca atcttatgcg ctatttccaa ctatgactgt ttttgataat
    41581 attgcatttg gtttaaaagt taagaaggta gctccagatg ttattaaagc taaagtatca
    41641 gcagtggcag caaaaattaa gatctctgat caacagttac agcgtaatgt atcagaatta
    41701 tctgggggtc aacaacaaag ggtagcattg gctcgtgctc tggttcttga acctaaaatt
    41761 ctttgtctag atgaaccatt gtcaaacctt gacgcaaaat tacgtgtaga tttgagaaaa
    41821 gagttgaaaa gacttcaaaa agagttaggt attactactt tatatgttac tcatgatcaa
    41881 gaggaagcct tgactttatc tgatagaatt gcagtcttta acaatggata catcgaacag
    41941 gtcggtacac cagtagagat ttatcataat tctcaaactg aatttgtatg tgatttcatt
    42001 ggagatatta atgttttgac cgatgaaaca gtccacgaag tattattgaa aaatacaagc
    42061 gttttcttag aggataaaaa aggatacatt cgattagaga aagttcgatt caatcgtgaa
    42121 actgaacaag attttattct aaaagggaca attattgatg ttgagttttc tggagttaca
    42181 attcactata caataaaagt ttctgaaagt cagattctta atgtaacaag tattgatagt
    42241 caggctgcta ttagatctgt cggagaaagt gtggaattat ttatcacacc atcagacgtt
    42301 ctgcaatttt aaggaggtgc agtatgcgtc ataaattaaa tttaaaagat tggcttattc
    42361 gtttagggtt aatctggttc ttagtaacat ttattattta tccaaacttt gatctagtag
    42421 tgaatgtatt tgtaaaagga ggagaatttt cccttgatgc tgtacatcgt gttctaaaat
    42481 ctcagagggc acttcagagt attatgaaca gttttaagtt agcattttca ctcattatta
    42541 cagttaatgt cgtaggtatt ctttgtgttc tatttacaga gtactttgat attaaaggtg
    42601 ctaaaatttt aaaattaggt tatatgacct ctttaattta tggaggagtg gttttagcga
    42661 ctggatataa atttgtctat ggtccttatg gattgattac aaaattttta caaaatgtta
    42721 tcccttcttt agactctaac tggtttattg ggtatggtgc agtcttattc attatgacat
    42781 tttcaggaac tgctaatcat acattgtttt taacaaatac aattcgaagc gttgactatc
    42841 acactattga ggctgctcga aatatgggag caaaaccatt tactgttttc cgaaaagtag
    42901 tgttaccaac cttaattcca actctatttg cacttactat tatggttttt cttagtggtt
    42961 tatctgcagt agcagcaccc atgattgttg gtggtaaaga atttcaaact ataaatccaa
    43021 tgattattac atttgcaggg atggggaatt ctcgtgattt agctgcctta cttgcaatta
    43081 ttttaggtat tgcaactaca attttgctta ctatcatgaa taagatagaa aaaggtggaa
    43141 attatatttc tatctctaag actaaagcgc ctcttaaaaa acaaaaaatt gcgtctaagc
    43201 cttggaatat cattgctcac attgtagcat atggattgtt cacagttttc atgcttccac
    43261 taatttttat agtattatac tcatttacag atccagttgc aattcaaaca ggtaacttaa
    43321 cattatcaaa ctttacttta gaaaattatc gcttattctt tagtaatagt gcggcattct
    43381 ctccattctt ggtcagcttt atttattcta ttattgctgc gacaacagca acaattctcg
    43441 cagttgtatt tgctcgtgtt gtcagaaaac ataaatctcg ttttgatttc ttatttgaat
    43501 atggtgctct acttccttgg ttactaccaa gtacactttt agcagtaagt ttattattta
    43561 cttttaatca gccacaattt cttgtcttga atcagatttt ggtaggtagt ttggtaattc
    43621 tacttattgc atatatagtt gtaaaaatcc cattttctta tagaatggta cgtgctattt
    43681 tatttagtgt tgatgatgag atggaagatg cagcaagaag tatgggtgct tcaccttttt
    43741 atactatgat gaaggttatc attccattta ttttaccggt tgttctctct gttattgctt
    43801 taaactttaa ctctttatta actgacttcg acttatctgt attcctttac catcccctag
    43861 ctcaaccatt aggtattacg attcgatctg caggtgatga aacagcaaca tctaatgcac
    43921 aagctctggt atttgtttat acaattgttc tgatgattat ttctggaacg gtattatact
    43981 tcacacaaag accggggcgt aaagtaagga aataatcatg acagccacta gtcttgggtt
    44041 atcaaatatt gaaatagttg tcaggattgt tttatcagta gtcattggta gtataattgg
    44101 tttagagaga gggagcaaat cccagcctgc aggcatccga acttatagta ttgtttgtct
    44161 agctgcatgt ttgattatga tgacgaatga atacgtatct tataaatttg ggacaggaga
    44221 tcctacacga ttaggagctc aagttatatc aggtgtgggt tttctaggcg ctggaacgat
    44281 tcttattaca gataaaaaga aaattacagg tctgacaact gcagcaggca tttgggcttc
    44341 ggcaggaatt ggattagcta ttggagtagg tttttatgag ggagctcttt tagtagccat
    44401 ttctgtttgg ggtgtgatat ccatgttcca accactaaaa aaatatctgc aaaatcgttc
    44461 taaaatgatt gaattgtata tagtggttaa atctacagaa gcctataatc gtgtattggt
    44521 ttattgtgca gaaaatggta tcagaatgac cgattcaaga acagcgtttg gagatgttaa
    44581 ttctgacaga attgaatact ttgatgttcc ggacaaaaaa atagcgtcat ttattactct
    44641 ggaattatca ggtagatttg aacatcttcg actgatggaa gaaattgcta atattgtagg
    44701 tgttatttat gtcgaagaaa ttagctgaaa tttagtaaac aaagggacag atgtttttgt
    44761 ccttttgctt tttagatgtt ttaatcatct aatttttgag tagatttttg ctcagaggtt
    44821 tttatgaaag attataaaat caattttgat ttaggtaaaa tagaatattt tgataataat
    44881 tgtttgatac aagtatacaa atttatttct ttttatgata tttgtgaaat ggtgtttgcc
    44941 tttcatttac ctcctgatga gttgataaca aatgttatct ttaaagaaaa aattaactct
    45001 atgttaaaat gttacattga caggctatta tatgttttta taaatcctac acattttact
    45061 gaaaaagtta atctacaatt ttatggcagt tttttctcat atgaatttat ttgtcgtgaa
    45121 gttggaaaca ttcttaaaaa taaaggtgtg aaatgcaatt taaacttttt tgaaggggaa
    45181 gaatatttgt aaaattaatt ttgtgaattt gtggatctta aataatttac taaattctct
    45241 tgttaaaaaa aattaaatat tgtatagtaa tattagaatg tttgtaatag aggactgaaa
    45301 tgaaaaatat aaatgggaaa aaggtaacta tttatgatat tgcacgttta tcaggttttt
    45361 ctccaaaaac agtttcacga gttattaatg gtggagtaaa tgttaaagaa gaaacttatc
    45421 aagcgattca aaaagttata gaggaattgt cgtatattcc aaatgcgtat gcaaaaaatt
    45481 taactaaaaa agaagctata aatatattga tttctgtaaa aaaaatcgac tcttttcctt
    45541 taatttggtt tcatacgctg ttagataaag tgttacggac gtgtaaagaa tttggtgtta
    45601 atgctatagt tgagtacttt ggagaggagg atacaattag taattcaatt atatcaagca
    45661 caggtagcct agtagatggt gttattgttt tttatgaaag tgtagatgat atcagaattc
    45721 agtatttaaa gaagaaccat atgccttttc ttgttttcgg tgaatctcaa acgtctggag
    45781 tagtctatgt atctaataat aattttcaag ctacttatga tatgatgaaa gctgtaactg
    45841 aagaaaaatt taaaaatatg tggttgctta tgggaggaga atctcatgtt aataaggatc
    45901 gtgaaagagg tgtgcgttct tttctgaatg ataaaaatta ctttatggat ttaaaagtca
    45961 tttatggctt atctacaatt gattcagttt attcttatgc aatgcagcac ttgactaccc
    46021 aaaattatcc ggacattatt tttgtttcag gagatgaaaa ggttcagggc ttgattcgtg
    46081 cgtgctatga gaaaggaatt cttattccag atgatatttc tattattgga tttgataata
    46141 ttcctatttc tcagtattat actccagctt tgtctacaat tgctcccaat tatgttaaat
    46201 tggctaaaga aatgatagaa ggtgttttag caattattaa aggggaaagt gtcacatctg
    46261 ttgaagtttc tcctaaattt gttaggagac agagtttcta gtattgttta attcttgaaa
    46321 atcctagtgg aaaagatgga gtgttctaaa ataagttctg tttagcctcc attcagtttc
    46381 tattgagttg gatccaattt ctaacaagtg ggacatgttc atgttcgatc taaggaagac
    46441 atggtcatat tcgaatgata ttttcaaaaa aatcgtaaaa aagtcttgac aaagaaaaaa
    46501 caaagtatta aaataagttc aacaaatcag aaaagtaact atttttgatc ttcagggagc
    46561 ctgtggtgat tgtgaatagg tggttggaag tagtgaaagt gggctgattt tgaaaatgaa
    46621 tttgaaacaa tgaaaattcg gtgcgcacac cttacagtgc agcttgttgt taaacaaggc
    46681 agagatgtaa agggatagtc cctttataat tgaggtggca ccgcgttacc aacgccctca
    46741 cacggaagta tattctgtgt gtgggctttt ttctatccgt cgtttggttt atcttttatt
    46801 agggccttaa gtcgctttga tgaacttgag ttctatctac agctccatgc ctactactaa
    46861 aagcaaacaa aaaggctgga ctaatacgaa aaaagctagt aatactcaat gaaaatcaaa
    46921 gagcaaacta ggaaactagc cgcaggctgc tcaaaacact gttttgaggt tgtggataga
    46981 actgacgaag tcagtaacca tacctacggc aaggcgacgt tgacgcggtt tgaagagatt
    47041 ttcgaagagt ataaaggtgt accgagatga acatctcttc atcaatgtct ctggtcgtgg
    47101 aggcaaggac ctagctgcga ttgcagatta ctagaagcta aaaaataata gatggaaaaa
    47161 ttacagttct ttctctcaca gagagcttgt ggttgctgaa aacaagcaga gaaagctgta
    47221 aagttgggtt catctgaaac gagagaagaa aacatcattc tcaagggagt gccctttatc
    47281 gcacagcctg ttacaggaga tatctgagac aggaatgaga gataggagaa atcctataat
    47341 tgaggtggca ccgcgaattt cgtcctcacg caagttattt tgcgtgggga tttttcatac
    47401 agtcaccacg gactagaagt agaactgaaa gggaaattac aatggaacga atcattcatg
    47461 gagatgtctt atcaccaatc ttggcttata tgcgcttaaa ggggcaacat aaggttattt
    47521 tagagagtat tccgagagac aaggaaacag ctcgtttttc tatcctagcc tataatccag
    47581 tttttgagat taagtttgaa aatggggttc tctatcaaaa tggtcaagtg attgatcggg
    47641 atcccttgga tttcctttat gaagtgattc ataagagtca gcaccactca gagctacctt
    47701 ttggtggtgg agccattggt tttgtgggtt acgatatgat ttcgctttat gaagaaattg
    47761 gtcaaatccc tgaggataca attgggacgc cagacatgca tttctttgtc tatgagagct
    47821 atatggtctt tgaccacaag aaggagaaga tacatgtcat agaggatgca ctttatagtg
    47881 agcgcagtca agaggccttg gaaaaatcct tgaaccaagt gcttgaggaa ttacgcattc
    47941 ctgctccaaa tgaatttgaa gatttggatc tatctccgtt agacttcaaa ccgcatatcg
    48001 ctccacataa gtttgaggga atggtagaaa cagctcgtga cttgattcgt aacggagata
    48061 tgttccaatg tgtactcagc cagcgttttt cagcagaagt tactggaaat ccatttgact
    48121 tctacagaaa tctccgcgtg actaatcctt ctaattacct ttatttctat gattttgggg
    48181 attatcaaat catcggagct agtccagaaa gtttagtttc tgtcaaaaat ggcatcgtga
    48241 caaccaatcc gattgcaggg acgcgaccaa gaggggctat ggatgaagaa gacaagacct
    48301 tggcgactga cctcctctct gatgagaagg aaacagcaga acatcgaatg ttggtagact
    48361 tggggcgtaa cgatattggc cgcatctctg aaacggccag tgtccaagtt actaagtata
    48421 tgaaggtgga gctcttccgc tacgtcatgc atttgaccag cgtggtcaag gggcgtttgc
    48481 ttccagaact cacggccatg gatgccttga aagctacact tcctgctgga accgtttctg
    48541 gagcaccaaa gattcgggcg atgagacgca tctatgaact ggaaacggaa aaacggggcg
    48601 tatatgcagg agcaatcggc tacttgtctg cgacgggtga tatggatttg gccattgcca
    48661 tccgaaccat gattctcaaa aatcaaagag cctatgtgca ggctggggca gggattgtct
    48721 acgactctat cgcccaaaac gaataccaag aaaccattaa caaagcaaaa tctatgacta
    48781 gaattggaga actaagacca tgattttatt gattgacaac tatgattctt ttacctataa
    48841 cttggcccaa tacattggga attttgcaga agttcaggtt ctgagaaatg atgattccaa
    48901 gctgtatgaa gaagctgaaa aagcagatgg tctggtcttt tctcctggtc ctggttggcc
    48961 agttgatgct ggaaagatgg aagacatgat tcgtgatttt gcaggcaaga agccgattct
    49021 tgggatttgt ttgggccacc aagccattgc agaagtcttt ggtggtaagc taggtttggc
    49081 tccaaaagtc atgcatggga aacagagcaa tatcaacttt gaagcgccat ctgttttgta
    49141 tcaaggtatt gaggaaggac gtgcggtcat gcgttatcac agtattttga ttgaggaaat
    49201 gccagaagac tttgaagtga cagctcgttc gactgatgac caagccatca tggggattca
    49261 acataaaaac ctaccgattt atggcttcca gtaccatcca gagagcattg gaacgccaga
    49321 cggcttgtct tctattcgga attttatcga gaaggttgta aagtgaggaa actaggatga
    49381 aagagattat tgaaaaacta gcaaaatttg aaaatttatc aggtgtggaa atgacggatg
    49441 tcattgagcg tatcgtaact gggcgtgtaa ctgaagcgca gattgcttct ctcctcttag
    49501 ctcttaagat gaagggggaa acacctgaag aacgcacagc cattgcccaa gtcatgagag
    49561 gacatgccca gcatattcca actgagattc atgatgccat ggacaactgt ggtacaggtg
    49621 gggacaagtc tttcagtttt aatatttcca caactgcagc ctttgtcttg gctggtggcg
    49681 gtattcacat ggccaagcat ggtaaccgct cgatttcttc taaatctggt tccgcagatg
    49741 tcctcgaagc cttgggaatc aatcttgacc tcaaaccagc tgaactaggt aaggtctttg
    49801 ataaaactgg aatcgtcttt ctcttcgcta aaaatatgca cccagctatg aaatacatca
    49861 tgccagctcg tttggaattg ggaattccaa cgattatgaa cttgactggt ccactgattc
    49921 atccaatggc tttagaaaca cagcttcttg gaattagtcg tccagaactc ctagaaagta
    49981 cagctcaggt tttgaaaaat atgggtcgca aacgtgccat cgtggttgct ggaccagaag
    50041 ggttggatga agctggcttg aacggaacaa ccaagattgc acttcttgaa aatggcgaaa
    50101 tcagcttgtc aagctttact ccagaggatt tgggaatgga aggctatgct atggaagata
    50161 ttcgtggtgg gaatgctcag gaaaatgcag aaattttgct tagcgttctg aaaaacgaag
    50221 caagtccatt cttggaaacg acagtcttga atgctggtct tggtttctat gctaatggta
    50281 agattgatag catcaaggaa ggagttgcct tggctcgtca agtgattgct agaggcaagg
    50341 cccttgaaaa actcagactg ttacaggagt accaaaaatg agtcaggaat ttttagcacg
    50401 aatcttagag cagaaggcgc gtgaggtgga gcagatgaag ctggagcaaa tccagcctct
    50461 gcgccagacc tatcgcttgg cagaattttt gaagaatcat caggaccgct tgcaggtaat
    50521 cgctgaggtc aagaaagcta gccctagttt gggagatatc aatctcgatg tggatattgt
    50581 gcaacaggcc cagacttatg aagaaaacgg agcagtgatg atttcggtgt tgacagatga
    50641 ggttttcttt aaagggcatt tggattatct acgggaaatt tccagtcagg tagagattcc
    50701 gacgctcaac aaagacttta tcatagatga aaagcaaatc atccgcgctc gcaatgcagg
    50761 tgcgacagtt atcttgctca ttgtggcagc cttgtccgaa gaacgcctca aggaactgta
    50821 tgactacgcg acagagcttg gtctggaagt cttagtggag actcacaatc tagctgaact
    50881 agaggtagcc cacagacttg gtgctgagat tatcggggtc aacaaccgca acttgactac
    50941 ctttgaggtc gacttgcaga ccagtgtaga tttagcccct tactttgagg aaggtcgcta
    51001 ttacatttct gaatctgcca ttttcacagg gcaggatgcg gaacgactag ccccatactt
    51061 taacggaatt ttggtaggga cagctcttat gcaggcagaa aatgtggccc agagaatcaa
    51121 ggagttgcag attgacaaag gttaaaattt gtggactatc gaccaaagaa gcggtggaaa
    51181 cagccgtttc agcaggagcc gactatatcg gttttgtctt tgcacctagt aaaagacagg
    51241 tgactttaga agaggcagct gagttggcaa agcttattcc tgcagatgtg aaaaaggttg
    51301 gagtatttgt ttcaccaagt cgggtagaac tgctggaagc gattgacaaa gttggcttgg
    51361 acttggttca agttcacggt caggtggcag atgatttatt tgagaatttg ccttgtgcta
    51421 gcattcaggc tgtgcaggta gatggagagg gtcatgtgcc caattctcag gcagactatc
    51481 tactctttga tgcccctgtg gctgggagtg gccagccctt tgattggggt caactggata
    51541 cgactggatt acctcagtct ttctttatcg caggtgggct taatgaagac aatgtagtaa
    51601 aagcaattca acactttact ccctatgcag tagatgtatc aagcggagtg gagacagatg
    51661 gacaaaaaga tcatgaaaag attagaagat ttatagagag ggtaaagaat ggcatatcaa
    51721 gaaccaaata aagatggatt ttacggaaaa ttcggcggac gttttgtccc agaaacattg
    51781 atgacagcag ttttggagtt ggagaaggcc taccgtgaaa gtcaggcaga cccaagtttc
    51841 caagaggaat taaaccaact tttgcgccag tatgtgggac gtgaaactcc cctttactac
    51901 gcaaaaaact tgacccagca tatcggcgga gccaagattt atctcaaacg ggaagacctt
    51961 aaccatacag gagcccacaa gattaacaat gccttaggac aagtttggct tgccaaacgc
    52021 atgggtaaaa agaaaattat cgcagaaact ggtgctggtc agcacggtgt ggcaactgca
    52081 actgctgcgg ccctctttaa catggaatgt accatctaca tgggtgagga agatgtcaaa
    52141 cgccaagccc tcaatgtctt ccgtatggag cttttgggag ctaaggtcga ggccgtgaca
    52201 gatggttcgc gcgtgctcaa ggatgcggtc aatgcagctc ttcgttcatg ggtggctaat
    52261 atagatgata cccactatat ccttggttct gccttggggc ctcatccatt tccagaaatt
    52321 gttcgtgact tccaaagtgt cattggtcga gaggctaaac aacagtaccg tgacttgaca
    52381 ggacaaaatc tgccagatgc cctagtagcc tgtgttggtg gtgggtcgaa tgccatcggt
    52441 ctcttccatc cctttgtaga agatgagtca gtagccatgt atggagctga agcggctgga
    52501 cttggtgtgg atacggagca ccacgcagct accttgacca agggtcgtcc aggtgtcctt
    52561 cacggttccc tcatggatgt gctccaagat gcccatggtc aaattcttga agccttctct
    52621 atctcagcag gtttggacta tcctggtatc ggtccagagc attctcacta ccacgatatt
    52681 aaacgtgcca gctatgtccc tgtgacagac gaagaagcct tggaaggatt ccaactcttg
    52741 tctcgtgtgg aagggattat cccagccttg gaatctagcc atgctatcgc ctttgcggtg
    52801 aaattggcca aagaacttgg accagaaaag tctatgattg tctgcctatc aggtcgtggg
    52861 gacaaggatg tggttcaagt caaggaccgc ttggaagcag atgcagcaaa gaagggagaa
    52921 gctcatgcct aagacactaa cagaaaaatt aaatgctatt aaagcagctg gaaaaggaat
    52981 ttttgttccc tatatcatgg ctggtgacca cgagaaaggt ttggacggtc ttgctgaaac
    53041 aattcacttt ttagaagatt tgggtgtctc tgcaattgaa gtgggtattc ccttttcaga
    53101 ccctgttgca gatggacctg ttatcgaaga agctggcttg cgcagtttag cccacgggac
    53161 ctctacccag gctttagttg aaaccttgaa aaccattgaa acagagattc cactggtcat
    53221 catgacctac ttcaaccccc tctttcagta cggtgtggag aactttgtca aagatctggc
    53281 tgatacagct gtgaagggct tgattatccc agacctgcct catgaacatg ccaactttgt
    53341 agaaccattt ttggcaaata cagatatcgc cttgattcct ttagtaagct tgaccacagg
    53401 aattgagcgc cagaaagagt tgattgcagg ggcggaggga ttcgtctatg ccgttgccat
    53461 caatggggtg acagggaaat caggcaatta ccgtgcagat ttggacaagc acttggcgca
    53521 acttcatcaa gtggccgaca tcccagtctt gacaggtttt ggtgtatcta gtcaagccga
    53581 tctggaacgc ttcaatgcgg tgtcagatgg tgttatcgtc ggttcaaaaa tagtaaaagc
    53641 tctccaccaa ggagagccga ttcaggattt tatcagacaa gcagtagctt accaaaaata
    53701 atcaaacaag tagcaagtaa gaggaaaggc acgaaaggaa gtctttcctt tttcttttgc
    53761 aggagaaagg tcagttttat agtgaattga atctggaata ttacactacg gttcctaaaa
    53821 tattttcaga aagcgatttg aatttcccaa taaatttgtt cagtttttaa ttgattttac
    53881 tatagaagat ataattttct aaattactct gacacagaac tttaagaaaa agataattat
    53941 tgtagtaatt tctttaagaa aatgatataa ttcattaaaa agtatttgga ggaggaagaa
    54001 ttatgttgaa tcaggatctc tttgattcgc ttgaggcaca aaaaattgta gatactttga
    54061 tgaaagggca aaaagattat gtagatgaac gtctagaaaa aagagagaca atgatagtgt
    54121 cgaatggtta tgcatggacg cgacctaatc atattgatac tgcatttgca tcagcagatt
    54181 tgtttgagta taaattacaa ttagcaggac agacttgggg atatttagaa tttgaaacaa
    54241 atacagaaaa atatgggaaa gtattgttaa ttataaaggg taagaagcga cttacgaacc
    54301 aatttccttt ggtacaaaaa aataagagtg gctacttatt tgaatacgct cagatgaata
    54361 cactttatct taatcaacat tcttcctaca aaaatgatga agatagtcat tcctttccaa
    54421 ttcagatgga gttagtttct gatgaaatga ttcaagaaat tgaacaagct actaaaaatt
    54481 cgaatatcga aaaatttatg attttaactt atgaggcgga ctcagaaaac aatattatat
    54541 ctgtagatgt tgttatgcct gatgcacgaa ctggtcagct acacttgatt caagatttgt
    54601 ctgagtatat tcaatcaagt tcgtaccatt tcgaagaagc taaatatcaa gatattccta
    54661 atttttcaga attatcggaa acagaagatt ttgaaattat tccaagaata gaaaaacaag
    54721 aaggtcaaaa gtagtaagga gtatataaat gtttaatggt cgggtattga aagaattacg
    54781 gctgttaaat ggtttaagta gagcagaatt agctcagaga attaatttaa cggaacaagc
    54841 catttggcag tttgagtcca acgaaacgaa acctaaatta tcaaccaaaa tgcatttggc
    54901 caaccaattt catgttgatt taacttattt tgaacaggaa gaagagagca ttcgatttga
    54961 ttcttctgta attgccttta gaaatgcaga cctagcaaca cggaaaacaa tagatattca
    55021 aactatgtat ttacataagg tagatagttt gattgattat tttgaaagtt ttgtaattat
    55081 acctaatatt ataattcatg acctaagtaa tgtagtgagt gaatcttatc ataagggaga
    55141 atccattgag gaattggctc tttatgccag ggaaaaatta ggtatttcaa aagataatca
    55201 tgatttgctt tataaattag aacgttcagg tatctatatc gtggaacgat taattaatgg
    55261 ccaagctgat gcttatagcg catggtcaaa attgggaaga ccttatattg tgttgggaac
    55321 gaataaatca tctgtacgtc gaaattttga cttagctcat gagctaggac atattctttt
    55381 acataaatat aaggatatga atgaagatgg cgatcgtttg gagcaagaag caaattattt
    55441 tgcatcatgt tttttattgc caaaagaaga gtttttagtc aaatttgaag agagggttgg
    55501 caagcgtgcc agcaatcctg atagttatat tttattgaag tcggatttga atgtttcgat
    55561 acaggcttta gagtatcgag cttttaagtt aggattattg actccaaagc aacattctta
    55621 cttttatcgt caaattgcgc aaaaaggtta caaaatgatt gaacctttgg atgatcaaat
    55681 ttttgttaaa aaaccaagca aagtaaagag tattctggac gtcgttttga gtaatcatct
    55741 agtcagtcta gcgactataa tgtctaaaca aagtatttgt ttacagttta taagcgaaat
    55801 attttcagtc gaaatgaaat tttttgatca gtatcaagaa gatagaagaa cagatcgatt
    55861 tgataacatc atccctttgt acaaaagaaa taatttataa tttaactgtg aaataatttc
    55921 atgaaggaca tatggcagaa attggatttt atcagacaag cagtagctta ccaaaaataa
    55981 tcaaacaagt agcaagtaag aggaaaggca cgaaaggaag tctttccttt ttcttttgca
    56041 ggataaaggc caggataccc gtcgcagaag caaactgaat caagatcagt aactccgtta
    56101 cgctaaagac gagagcacaa gaagctaaaa agaggaaatc tcctgcgccc atgcggatat
    56161 cgataaaatg agccaaaatt ccaagagcaa ggaaggagac catgaccaga ttccagccag
    56221 aggaagctat taggattagg tggaaagtca tccagaccag taagggatat tcctgatggt
    56281 gaaagtcgta gatacccaag gtcaaaccag cggtgattag gacgacttgc cccaaggaaa
    56341 gcaattccca agagtaaagc agaaagagga gtcctaagac taattcaaag agggcatacc
    56401 agacaggata gcgaactttg cagtagcgac agcgaaagcg attgaagacc tgtgagagaa
    56461 tcggaatcaa atctaaggga cgcaagcgag tctgacagga atcgcagtga ctggctgaac
    56521 tgataatgga ttgctctgga aaacggtcaa tgaccaaacc aagaaaggaa gcgagaatgc
    56581 tcccgacgag aaaaaaataa aaatcaatca tacttatcta ttcgtaaaaa atgggagaaa
    56641 tagtataatg gagaaacata gataagatgg tgaggaaaag atgacaattc gttttgaaga
    56701 aaaggtgagt atagaaaacg ctcaatttgt atgccagtgg tccaactccc taggcaaatc
    56761 ctttcaagaa caatggatgg gaccaaggat tccttttcta ctgacccttc aagccttgga
    56821 aggagtcttt tcaatctttg atgaacaaga gtttgtggga cttatccaga aaatcaggct
    56881 agaagacagc aatcttcata tcgggagatt ttttatcaac ccccagaaac aggagcaaga
    56941 cttaggtagc caggctttaa ggaaatttgt tagtttggcc tttgaaaatg aagatataga
    57001 tagtatttct ctaaatgtct tcgaggcaaa tcaaagagct cagaatcttt accaaaaaga
    57061 aggatttgaa atcgttcaaa tggttgaagc acctgtacga aaatatagta gattgaaact
    57121 agaatag
//
LOCUS       DBEJHE010000012        48481 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC4 isolate 671759
            SAMN38261586-rid24793303.denovo.12, whole genome shotgun sequence.
ACCESSION   DBEJHE010000012 DBEJHE010000000
VERSION     DBEJHE010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261586
            Sequence Read Archive: SRR26833752
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 48481)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48481)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576136.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576136.1
            Genome Coverage       :: 109x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 19:48:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,067
            CDSs (total)                      :: 2,029
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 131
            CDSs (without protein)            :: 131
            Pseudo Genes (ambiguous residues) :: 0 of 131
            Pseudo Genes (frameshifted)       :: 64 of 131
            Pseudo Genes (incomplete)         :: 59 of 131
            Pseudo Genes (internal stop)      :: 46 of 131
            Pseudo Genes (multiple problems)  :: 32 of 131
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48481
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261586-rid24793303.denovo.12"
                     /strain="GPSC4"
                     /isolate="671759"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(155..1141)
                     /locus_tag="ACL3EZ_000979"
     CDS             complement(155..1141)
                     /locus_tag="ACL3EZ_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGR0392573.1"
                     /translation="MPVTIKDVAKAAGVSPSTVTRVIQNKSTISDETKKRVRKAMKEL
                     NYHPNLNARSLVSSYTQVIGLVLPDDSDAFYQNPFFPSVLRGISQVASENHYAIQIAT
                     GKDEKERLNAISQMVYGKRVDGLIFLYAQEEDPLVKLVAEEQFPFLILGKSLSPFIPL
                     VDNDNVQAGFDATEYFIKKGCKRIAFIGGSKKLFVTKDRLTGYEQALKHYKLTTDNNR
                     IYFADEFLEEKGYKFSKRLFKHDPQIDAIITTDSLLAEGVCNYIAKHQLDVPVLSFDS
                     VNPKLNLAAYVDINSLELGRVSLETILQIINDNKNNKQICYRQLIAHKIIEK"
     gene            complement(1151..1951)
                     /locus_tag="ACL3EZ_000980"
     CDS             complement(1151..1951)
                     /locus_tag="ACL3EZ_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000938258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HGR0392574.1"
                     /translation="MLPYPFSYFSSIWGFRKPLSKRFELNWFQLLFTSIFLISLSMVP
                     IAIQNSSQETYPLETFIDNVYEPLTNEVVQDLSEHATIVDGTLTYTGTASQAPSVVIG
                     PGQIKELPKDLQLHFDTNELVISKESKELTRISYRAIQTESFKSKDSLTQAISKDWYQ
                     QNRVYISLFLVLGASFLFGLNFFIVSLGASLLLYITKKSRLFSFRTFKECYHFILNCL
                     GLPTLITLILGLFGQNMTTLITVQNILFVLYLVTIFYKTHFRDPNYHK"
     gene            complement(2212..3054)
                     /locus_tag="ACL3EZ_000981"
     CDS             complement(2212..3054)
                     /locus_tag="ACL3EZ_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001065636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HGR0392575.1"
                     /translation="MNNSIKLKRRLTQSLTYLYLIGLSIVIIYPLLITIMSAFKAGNV
                     SAFKLDTNIDLNFDNFKGLFTETLYGTWYLNTLIIALITMAVQTSIIVLAGYAYSRYN
                     FLARKQSLVFFLIIQMVPTMAALTAFFVMALMLNALNHNWFLIFLYVGGGIPMNAWLM
                     KGYFDTVPMSLDESAKLDGAGHFRRFWQIVLPLVRPMVAVQALWAFMGPFGDYILSSF
                     LLREKEYFTVAVGLQTFVNNAKNLKIAYFSAGAILIALPICILFFFLQKNFVSGLTSG
                     GDKG"
     gene            complement(3056..4348)
                     /locus_tag="ACL3EZ_000982"
     CDS             complement(3056..4348)
                     /locus_tag="ACL3EZ_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000414940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HGR0392576.1"
                     /translation="MEKQQPSKAALLSIIPGLGQIYNKQKAKGFIFLGVTIVFVLYFL
                     ALATPELSNLITLGDKPGRDNSLFMLIRGAFHLIFVIVYVLFYFSNIKDAHTIAKRIN
                     NGIPVPRTLKDMIKGIYENGFPYLLIIPSYVAMTFAIIFPVIVTLMIAFTNYDFQHLP
                     PNKLLDWVGLTNFTNIWSLSTFRSAFGSVLSWTIIWALAASTLQIVIGIFTAIIANQP
                     FIKGKRIFGVIFLLPWAVPAFITILTFSNMFNDSVGAINTQVLPILAKFLPFLDGALI
                     PWKTDPTWTKIALIMMQGWLGFPYIYVLTLGILQSIPNDLYEAAYIDGANAWQKFRNI
                     TFPMILAVAAPTLISQYTFNFNNFSIMYLFNGGGPGSVGGGAGSTDILISWIYRLTTG
                     TSPQYSMAAAVTLIISIIVISISMIAFKKLHAFDMEDV"
     gene            complement(4459..5730)
                     /locus_tag="ACL3EZ_000983"
     CDS             complement(4459..5730)
                     /locus_tag="ACL3EZ_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000095461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HGR0392577.1"
                     /translation="MSSKFMKSTAVLGTATLASLLLVACGSKTADKPADSGSSEVKEL
                     TVYVDEGYKSYIEEVAKAYEKEAGVKVTLKTGDALGGLDKLSLDNQSGNVPDVMMAPY
                     DRVGSLGSDGQLSEVKLSDGAKTDDTTKSLVTAANGKVYGAPAVIESLVMYYNKDLVK
                     DAPKTFADLENLAKDSKYAFAGEDGKTTAFLADWTNFYYTYGLLAGNGAYVFGQNGKD
                     AKDIGLANDGSIAGINYAKSWYEKWPKGMQDTEGAGNLIQTQFQEGKTAAIIDGPWKA
                     QAFKDAKVNYGVATIPTLPNGKEYAAFGGGKAWVIPQAVKNLEASQKFVDFLVATEQQ
                     KVLYDKTNEIPANTEARSYAEGKNDELTTAVIKQFKNTQPLPNISQMSAVWDPAKNML
                     FDAVSGQKDAKTAANDAVTLIKETIKQKFGE"
     gene            6265..7797
                     /gene="malQ"
                     /locus_tag="ACL3EZ_000984"
                     /pseudo
     CDS             6265..7797
                     /gene="malQ"
                     /locus_tag="ACL3EZ_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847831.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004134 - 4-alpha-glucanotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0005980 - glycogen catabolic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
     gene            7823..10081
                     /gene="glgP"
                     /locus_tag="ACL3EZ_000985"
     CDS             7823..10081
                     /gene="glgP"
                     /locus_tag="ACL3EZ_000985"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000950172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004645 - 1,4-alpha-oligoglucan
                     phosphorylase activity [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan family
                     phosphorylase"
                     /protein_id="HGR0392578.1"
                     /translation="MLSLQEFVQNRYNKTIAECSNEELYLALLNYSKLASSQKPVNTG
                     KKKVYYISAEFLIGKLLSNNLINLGLYDDVKKELAAAGKDLIEVEEVELEPSLGNGGL
                     GRLAACFIDSIATLGLNGDGVGLNYHFGLFQQVLKNNQQETIPNAWLTEQNWLVRSSR
                     SYQVPFADFTLTSTLYDIDVTGYETATKNRLRLFDLDSVDSSIIKDGINFDKTDIARN
                     LTLFLYPDDSDRQGELLRIFQQYFMVSNGAQLIIDEAIEKGSNLHDLADYAVVQINDT
                     HPSMVIPELIRLLTARGIELDEAISIVRSMTAYTNHTILAEALEKWPLEFLQEVVPHL
                     VPIIEELDRRVKAEYKDPAVQIIDESGRVHMAHMDIHYGYSVNGVAALHTEILKNSEL
                     KAFYDLYPEKFNNKTNGITFRRWLMHANPRLSHYLDEILGDGWHHEADELEKLLSYED
                     KAAVKEKLESIKAHNKRKLARHLKEHQGVEINPNSIFDIQIKRLHEYKRQQMNALYVI
                     HKYLDIKAGNIPARPITIFFGGKAAPAYTIAQDIIHLILCMSEVIANDPAVAPHLQVV
                     MVENYNVTAASFLIPACDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIAE
                     LVGEENIYIFGEDSETVIDLYAKAAYKSSEFYAREAIKPLVDFIVSDAVLAAGNKERL
                     ERLYNELINKDWFMTLLDLEDYIKVKEQMLADYEDRDAWLDKVIVNISKAGFFSSDRT
                     IAQYNEDIWHLN"
     gene            complement(11126..11698)
                     /locus_tag="ACL3EZ_000986"
     CDS             complement(11126..11698)
                     /locus_tag="ACL3EZ_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0392579.1"
                     /translation="MNKLMKFISVFLTSIVLIVSAIPSVSAVYASEQVSQIETNMELQ
                     PVTSLTEEQINTLANEIQSFHPDVSQQWIKEVINRQLQGDYTIPPTYSPFRAAWQGIT
                     VNQMGALLDTTIALALGGTTAGLANLIKVKGKHAAKSAIRSAISRYLGSWFVNDVALE
                     SAMNLLSPGTYLAQLWDKNDAIPNNGRINF"
     gene            11776..11982
                     /locus_tag="ACL3EZ_000987"
     CDS             11776..11982
                     /locus_tag="ACL3EZ_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0392580.1"
                     /translation="MLKKYFSKYKWTDLFWILFVILTCLYIGNHDLFTLNHQEFSFRG
                     SFWGLVLALYHLLFIDKFVISNRK"
     gene            complement(12321..13169)
                     /locus_tag="ACL3EZ_000988"
     CDS             complement(12321..13169)
                     /locus_tag="ACL3EZ_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative RNA methyltransferase"
                     /protein_id="HGR0392581.1"
                     /translation="MNTNLKPKLQRFASATAFACPICQENLTLLETNFKCCNRHSFDL
                     AKFGYVNLAPQIKQSANYDKENFQNRQQILEAGFYQAILDAVSDLLASSKTTTTILDI
                     GCGEGFYSRKLQESHSEKTFYAFDISKDSVQIAAKSEPNWAVNWFVGDLARLPIKDAN
                     MDILLDIFSPANYGEFRRVLSKDGILIKVIPTENHLKEIRQRVQDQLTNKEYSNQDIK
                     EHFQEHFTILSSQTASLTKTITAEQLQALLSMTPLLFHVDQSKIDWSQLTEITIEAEI
                     LVGKAF"
     gene            13321..13599
                     /locus_tag="ACL3EZ_000989"
     CDS             13321..13599
                     /locus_tag="ACL3EZ_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003075836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6110 family protein"
                     /protein_id="HGR0392582.1"
                     /translation="MLKEVLTVAKVAKKSSLFLGGVAFGTLGLKILASKEAKKGYSKA
                     LAKAYKLKDELDASVSVVKQHGDDVLQDAKYLYEQEKKEEQLDSLIGE"
     gene            13601..15664
                     /locus_tag="ACL3EZ_000990"
     CDS             13601..15664
                     /locus_tag="ACL3EZ_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HGR0392583.1"
                     /translation="MSFKVLHRGYQHIRLSSSFSLTLDIQDYLRSLARDEKGIESIQF
                     YMDQQHFTLRIKEGFSVLDNAEAFLKRIDKGKVSELMTLPIRREESAYSIVSGAAVKR
                     VLFRSFVPYPIRYIWTCYQALGYIREAYQTLARKELTMEVLDCSAILLSLFMNQSKTA
                     SNIMFMLDLGNHLDQWSLKKTATDLEQSLLAKESDVFLVQGDTVVSIKSSDVQIGDVL
                     ILSQGNEILFDGQVVSGLGMVNESSLTGESFPVEKRESDLVCANTVLETGELRIRVTD
                     NQMNSRILQLIKLMKKSEENKKTKQRYFIKMADKVVKYNFLGAGLTYLLTGSFSKAIS
                     FLLVDFSCALKISTPVAYLTVIKEGLNREMVIKDGDVLEKYLEVDTFLFDKTGTITTS
                     YPIVEKVLPFGDYSEEDILRISACLEEHIYHPIANAIVKQAEIEGIEHEEMHGKLQYI
                     ASKGIKSHIDGQPVLIGNYVLMQDEQIHISSEQNALIEEYKSHYNLLFLAYQNELIGM
                     FCIHTPLRKEAKTALDKLKAQGKKLILATGDTLIRTEELVKDLPFDQVYTDLKPDGKF
                     ELVEKLQKAGHTILMVGDGLNDSAALTLSDIGVVMNESADISKQMSDILLLDNRLDFF
                     QELDSLSSSLQTLIKKNIQDTVVVNSSLIGFGLFNWLSPSNLSILHNLTTLRIVLRSL
                     SIKNR"
     gene            complement(15742..16998)
                     /gene="tyrS"
                     /locus_tag="ACL3EZ_000991"
     CDS             complement(15742..16998)
                     /gene="tyrS"
                     /locus_tag="ACL3EZ_000991"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004831 - tyrosine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006437 - tyrosyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HGR0392584.1"
                     /translation="MHIFDELKERGLIFQTTDEEALRKALEEGQVSYYTGYDPTADSL
                     HLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERSLQTKDTVDGWVKSIQ
                     GQLSRFLDFENGENKAVMVNNYDWFGSISFIDFLRDIGKYFTVNYMMSKESVKKRIET
                     GISYTEFAYQIMQGYDFFVLNQDHNVTLQIGGSDQWGNMTAGTELLRRKADKTGHVIT
                     VPLITDATGKKFGKSEGNAVWLNPEKTSPYEMYQFWMNVMDADAVRFLKIFTFLSLDE
                     IEDIRKQFEAAPHERLAQKVLAREVVTLVHGEESYKEALNITEQLFAGNIKNLSVKEL
                     KQGLRGVPNYQVQADEHNNIVELLVSSGIVNSKRQAREDVQNGAIYVNGDRIQDLDYV
                     LSDADKLENELTVIRRGKKKYFVLTY"
     gene            17140..19605
                     /gene="pbp1b"
                     /locus_tag="ACL3EZ_000992"
     CDS             17140..19605
                     /gene="pbp1b"
                     /locus_tag="ACL3EZ_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein PBP1B"
                     /protein_id="HGR0392585.1"
                     /translation="MQNQLNELKRKMLEFFQQKQKNKKSARPGKKGSSTKKSKTLDKS
                     AIFPAILLSIKALFNLLFVLGFLGGMLGAGIALGYGVALFDKVRVPQTEELVNQVKDI
                     SSISEITYSDGTVIASIESDLLRTSISSEQISENLKKAIIATEDEHFKEHKGVVPKAV
                     IRATLGKFVGLASSSGGSTLTQQLIKQQVVGDAPTLARKAAEIVDALALERAMNKDEI
                     LTTYLNVAPFGRNNKGQNIAGARQAAEGIFGVDASQLTVPQAAFLAGLPQSPITYSPY
                     ENTGELKSDEDLEIGLRRAKAVLYSMYRTGALSKDEYSQYKDYDLKQDFLPSGTVTGI
                     SRDYLYFTTLAEAQERMYDYLAQRDNVSAKELKNEATQKFYRDLAAKEIENGGYKITT
                     TIDQKIHSAMQSAVADYGYLLDDGTGRVEVGNVLMDNQTGAILGFVGGRNYQENQNNH
                     AFDTKRSPASTTKPLLAYGIAIDQGLMGSETILSNYPTNFANGNPIMYANSKGTGMMT
                     LGEALNYSWNIPAYWTYRMLRENGVDVKGYMEKMGYEIPEYGIESLPMGGGIEVTVAQ
                     HTNGYQTLANNGVYHQKHVISKIEAADGRVVYEYQDKPVQVYSKATATIMQGLLREVL
                     SSRVTTTFKSNLTSLNPTLANADWIGKTGTTNQDENMWLMLSTPRLTLGGWIGHDDNH
                     SLSRRAGYSNNSNYMAHLVNAIQQASPSIWGNERFALDPSVVKSEVLKSTGQKPGKVS
                     VEGKEVEVTGSTVTSYWANKAGATATSYRFAIGGSDADYQNAWSSIVGSLPTPSSSSS
                     SSSSSSDSSNSSTTRPSSSRARR"
     gene            19670..20581
                     /locus_tag="ACL3EZ_000993"
     CDS             19670..20581
                     /locus_tag="ACL3EZ_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HGR0392586.1"
                     /translation="MNQYQKKIVNGKIYSLLSGLIWGICGILGEYFFTHYQVSSGWIT
                     SMRLTLAGSLVLIWSAIQLKSQVLDIWRDKKNYLPFLAYAILGIFSVQYFFYLCVEYS
                     NATTATILQFISPVFILFYNRLVYQKRASKSAVFYVLVAMLGVCLMATKGDLSQLSMT
                     PLALITGLLSAMGVMFNVILPQPFAKRYGFVPTVGWGMILAGLFSNVLSPVYQLSFTL
                     DIWSILICLIIAFFGTAFAFFISMKAVSLVSPLVVSVISASEPLSSALLSVLFLGLVV
                     DWSLLLAIALIILPMIFLSIEEAKESR"
     gene            20811..21509
                     /gene="dapD"
                     /locus_tag="ACL3EZ_000994"
     CDS             20811..21509
                     /gene="dapD"
                     /locus_tag="ACL3EZ_000994"
                     /EC_number="2.3.1.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047200 - tetrahydrodipicolinate
                     N-acetyltransferase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HGR0392587.1"
                     /translation="MTATKMNAQEIIQFIANAEKKTSVKVTFEGQLATAVPSSVVKLG
                     NVLFGDWKDVAPLLEGLVENQDYVVEQDARNSAVPLLDKRAINARIEPGAIIRDQVEI
                     GDNAVIMMGAVINIGAEIGAGTMIDMGAILGGRAIVGKNSHVGAGAVLAGVIEPASAE
                     PVRVGDNVLIGANAVVIEGVQIGSGSVVAAGAIVTQDVSENVVVAGVPARIIKEIDAQ
                     TQQKTALEDALRTL"
     gene            21577..22707
                     /locus_tag="ACL3EZ_000995"
     CDS             21577..22707
                     /locus_tag="ACL3EZ_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyldiaminopimelate deacetylase"
                     /protein_id="HGR0392588.1"
                     /translation="MLDLIQTRRALHQIPEIGLEEFKTQAYLLDVIEKLTTGKDFVQI
                     RTWRTGILVYLQGSQPERTIGWRTDIDGLPIVEQTGLPFASQHQGRMHACGHDFHMTI
                     ALGCLERALEEQPKNNLLFLFQPAEENEAGGMLMYEDGAFGDWLPNQFYGLHVRPDLK
                     VGQIATNTHTLFAGTCEVKIHFKGKDGHAAFPHEANDALVAASYFVTQVQSVVSRNVN
                     PIEGAVVTFGIFQAGTTNNVITDTAFLHGTIRALTQDMSLLVQKRVKTVAEGVAAAFD
                     MEVEVELKQGGYLPVENNPALARELMDFFDEKDGIELIDIEPAMTGEDFGYLLSKVDG
                     VMFWLGIDSPYALHHSQMSPKEEVLAIGVAAVSSFLKKKAAE"
     gene            22719..23258
                     /locus_tag="ACL3EZ_000996"
     CDS             22719..23258
                     /locus_tag="ACL3EZ_000996"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030272 - 5-formyltetrahydrofolate
                     cyclo-ligase activity [Evidence IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HGR0392589.1"
                     /translation="MKSELRKQVLHEMKALSQEQKQAIDQALTERILQHPFYQEAKVI
                     ATYLSFSHEFQTRELIEQALKDGKKVLIPKTYPKGRMDFVVYDPQQLVKTAFALLEPQ
                     GDLEVVDASQIDLIHVPGLAFTTDGYRIGYGGGYYDRYLEHFSGHTLSTVHPCQIQDF
                     IPENHDIPVQEVLIDEGNL"
     gene            23242..23919
                     /locus_tag="ACL3EZ_000997"
     CDS             23242..23919
                     /locus_tag="ACL3EZ_000997"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HGR0392590.1"
                     /translation="MKEIFDRRYPVTSFFLLVTALVFLLMLVTAGGNFDRADTLFRFG
                     AMYGPAIRLFPEQVWRLLSAIFVHIGWEHFIVNMLSLYYLGRQVEEIFGSKQFFFLYL
                     LSGMMGNLFVFVFSPKSLAAGASTSLYGLFAAIIVLRYATRNPYIQQLGQSYLTLFVV
                     NIIGSVLIPGISLAGHIGGAVGGAFLAVIFPVRGEKRMYNTSQRLGAVVLFVGLAILL
                     FYKGMGM"
     gene            complement(23991..24890)
                     /gene="galU"
                     /locus_tag="ACL3EZ_000998"
     CDS             complement(23991..24890)
                     /gene="galU"
                     /locus_tag="ACL3EZ_000998"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003983 - UTP:glucose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0006011 - UDP-glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HGR0392591.1"
                     /translation="MTSKVRKAVIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVE
                     EALKSGIEDILVVTGKSKRSIEDHFDSNFELEYNLKEKGKTDLLKLVDKTTDMRLHFI
                     RQTHPRGLGDAVLQAKAFVGNEPFVVMLGDDLMDITDEKAVPLTKQLMDDYERTHAST
                     IAVMPVPHDEVSAYGVIAPQGEGKDGLYSVETFVEKPAPEDAPSDLAIIGRYLLTPEI
                     FQILENQAPGAGNEIQLTDAIDTLNKTQRVFAREFNGARYDVGDKFGFMKTSIDYALK
                     HPQVKDDLKNYLIQLGKELTEKE"
     gene            complement(24912..25928)
                     /locus_tag="ACL3EZ_000999"
     CDS             complement(24912..25928)
                     /locus_tag="ACL3EZ_000999"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009331 - glycerol-3-phosphate
                     dehydrogenase (FAD) complex [Evidence IEA];
                     GO_function: GO:0047952 - glycerol-3-phosphate
                     dehydrogenase [NAD(P)+] activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0046168 - glycerol-3-phosphate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HGR0392592.1"
                     /translation="MEKQTVAVLGPGSWGTALSQVLNDNGHEVRIWGNLPEQINEINT
                     HHTNKHYFKDVVLDENIIAYTDLAETLKNVDAILFVVPTKVTRLVAQQVAQTLDHKVI
                     IMHASKGLEPDSHKRLSTILEEEIPEHLRSDIVVVSGPSHAEETIVRDLTLITAASKD
                     LQTAQYVQELFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAII
                     ARGLAEITRLGVALGASPLTYSGLSGVGDLIVTGTSIHSRNWRAGDALGRGESLADIE
                     ANMGMVIEGISTTRAAYELAQELGVYMPITQAIYQVIYHGTNIKDAIYDIMNNEFKAE
                     NEWS"
     gene            26086..26580
                     /locus_tag="ACL3EZ_001000"
     CDS             26086..26580
                     /locus_tag="ACL3EZ_001000"
                     /inference="COORDINATES: protein motif:HMM:NF013540.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGR0392593.1"
                     /translation="MIQYMLIIEVNNSGSSCRLREFGEKIKRLRLAKKISRSEFCGDE
                     SELSIRQLIRIENGESRPTLTKLKYIAERLEVEDYKLMPSYIELDKEYLELKYFLMRT
                     PTYEDETIAQKKESVFDKIFEEYYDRLPEEERFIIPNYSYLALANYTVQKLPEKLVEI
                     LSFW"
     gene            complement(26703..27125)
                     /locus_tag="ACL3EZ_001001"
                     /pseudo
     CDS             complement(26703..27125)
                     /locus_tag="ACL3EZ_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(27187..27837)
                     /gene="phoU"
                     /locus_tag="ACL3EZ_001002"
     CDS             complement(27187..27837)
                     /gene="phoU"
                     /locus_tag="ACL3EZ_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA];
                     GO_process: GO:0030643 - intracellular phosphate ion
                     homeostasis [Evidence IEA];
                     GO_process: GO:0045936 - negative regulation of phosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HGR0392594.1"
                     /translation="MRNQFDLELHELEQSFLGLGQLVLETASKALLALASKDKEMAEL
                     IINKDHAINQGQSAIELTCARLLALQQPQVSDLRFVISIMSSCSDLERMGDHMAGIAK
                     AVLQLKENQLAPDEEQLHQMGKLSLSMLADLLVAFPLHQASKAISIAQKDEQIDQYYY
                     ALSKEIIGLMKDQETSIPNGTQYLYIIGHLERFADYIANICERLVYLETGELVDLN"
     gene            complement(27852..28604)
                     /gene="pstB"
                     /locus_tag="ACL3EZ_001003"
     CDS             complement(27852..28604)
                     /gene="pstB"
                     /locus_tag="ACL3EZ_001003"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HGR0392595.1"
                     /translation="MGTFSVRHLDLFYGDFQALKNISIQLPERQITALIGPSGCGKST
                     FLKTLNRMNDLVPSCHIEGQVLLDEQDIYSSKFNLNQLRKRVGMVFQQPNPFAMSIYD
                     NVAYGPRTHGIRDKKQLDALVEKSLKGAAIWEEVKDDLKKSAMSLSGGQQQRLCIARA
                     LAVEPDILLMDEPTSALDPISTLKIEDLIQQLKKDYTIIIVTHNMQQASRISDKTAFF
                     LTGEICEFGDTVDVFTNPKDQRTEDYISGRFG"
     gene            complement(28606..29421)
                     /gene="pstA"
                     /locus_tag="ACL3EZ_001004"
     CDS             complement(28606..29421)
                     /gene="pstA"
                     /locus_tag="ACL3EZ_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HGR0392596.1"
                     /translation="MSKYLLKLLVYCFSALTFGSLFLIIGFILIKGLPHLSLSLFSWT
                     YTSENISLMPAIISTVILVFGALLLALPIGIFAGFYLVEYTKKDSLCVKIMRLASDTL
                     SGIPSIVFGLFGMLFFVVFLGFQYSLLSGILTSVIMVLPVIIRSTEEALLSVSDSMRQ
                     ASYGLGAGKLRTVFRIVLPVAMPGILAGVILAIGRIVGETAALMYTLGTSTNTPSSLM
                     SSGRSLALHMYMLSSEGLHVNEAYATGVILIITVLMINTLSSLLSRKLVKGAS"
     gene            complement(29414..30277)
                     /gene="pstC"
                     /locus_tag="ACL3EZ_001005"
     CDS             complement(29414..30277)
                     /gene="pstC"
                     /locus_tag="ACL3EZ_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HGR0392597.1"
                     /translation="MIKQAFKEAVFRAIFFMSATVAVVAILLICFFIFSNGLPFMANY
                     GFARFLLGSDWSPTNIPASYGILPMIVGSLLITLGAIVIGVPTGILTSVFMVYYCPKP
                     VYGFLKSAINLMAAIPSIVYGFFGLQLLVPWIRSFLGNGMSVLTASLLLGIMILPTII
                     SLSESAIRTVPKTYYSGSLALGASHERSIFSVILPAARSGILSAVILGIGRAVGETMA
                     VILVAGNQPIIPSGLFSGTRTLTTNIVLEMAYASGQHREALIATSAVLFFLILLINAY
                     FAYLKGKSSYE"
     gene            complement(30395..31270)
                     /locus_tag="ACL3EZ_001006"
     CDS             complement(30395..31270)
                     /locus_tag="ACL3EZ_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HGR0392598.1"
                     /translation="MKFKKMLTLAAIGLSGFGLVACGNQSAASKQSASGTIEVISREN
                     GSGTRGAFTEITGILKKDGDKKIDNTAKTAVIQNSTEGVLSAVQGNANAIGYISLGSL
                     TKSVKALEIDGVKASRDTVLDGEYPLQRPFNIVWSSNLSKLGQDFISFIHSKQGQQVV
                     TDNKFIEAKTETTEYTSQHLSGKLSVVGSTSVSSLMEKLAEAYKKENPEVTIDITSNG
                     SSAGITAVKEKTADIGMVSRELTPEEGKSLTHDAIALDGIAVVVNNDNKASQVSMAEL
                     ADVFSGKLTTWDKIK"
     gene            complement(31437..32768)
                     /gene="pnpS"
                     /locus_tag="ACL3EZ_001007"
     CDS             complement(31437..32768)
                     /gene="pnpS"
                     /locus_tag="ACL3EZ_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system histidine kinase PnpS"
                     /protein_id="HGR0392599.1"
                     /translation="MKRYLQFWLVNLSVSLILIAGMALTWISKGIGLFLLALSLGQGG
                     YWLFCLWKWEVAFETLHQPLLTSSEYFLEKGQEDLKSLAQYVSGLKTKVSQQDQQYKD
                     LAETMEVLLSHLTMGTFLVSAQGQMLLSSRSLPHYFPDVDGDISSLDDLKRMDIRNLV
                     HQAFDQKTRLKQEVSGFHEGDLILEVTAVPVFSPTQSVEAVLVLLYDLTTIRTYEKLN
                     LAFVSNASHELRTPVTSIKGFAETIKGMSAEEEALKDDFLDIIYKESLRLEHIVEHLL
                     TLSKAQQMPIQWTTLSLAEFVQDLTQSLQPQLKKKDLQLKVQVPDDVTLVSDSQLLSQ
                     ILLNLLSNAIRYTEQGGKIEVKTQKVNEGIKISVSDTGIGISQLEQDRIFERFYRVNK
                     GRSRQTGGTGLGLAIVKELSQLLGGQVTVTSQLGRGSCFTIFLPNQSFAQD"
     gene            complement(32769..33476)
                     /locus_tag="ACL3EZ_001008"
     CDS             complement(32769..33476)
                     /locus_tag="ACL3EZ_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGR0392600.1"
                     /translation="MTKQVLLVDDEEHILKLLDYHLSKEGFSTQLVTNGRKALALAET
                     EPFDFILLDIMLPQLDGMEVCKRLRAKGVKTPIMMVSAKSDEFDKVLALELGADDYLT
                     KPFSPRELLARVKAVLRRTKGEQEGDDSDNIADDSWLFGTLKVYPERHEVYKANKLLS
                     LTPKEFELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKA
                     PQFIRTIRGYGYKFKEL"
     gene            complement(33560..34036)
                     /locus_tag="ACL3EZ_001009"
     CDS             complement(33560..34036)
                     /locus_tag="ACL3EZ_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000356607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HGR0392601.1"
                     /translation="MDKEDLIRTLELAPHVEGGYFRQTKKASDTINLAGKGRALYTSI
                     YFLLEETNPSHFHRLTADEIWYFHAGSPLTVHMITADGHYEAVTLGLDISKGQQLHYC
                     VPKGTIWGSTVDKDYALVSCLVAPGFEFEDFELFERVDLLATYPEHKEMIERLTRY"
     gene            34043..34570
                     /locus_tag="ACL3EZ_001010"
                     /pseudo
     CDS             34043..34570
                     /locus_tag="ACL3EZ_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            complement(34761..36452)
                     /gene="argS"
                     /locus_tag="ACL3EZ_001011"
     CDS             complement(34761..36452)
                     /gene="argS"
                     /locus_tag="ACL3EZ_001011"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015632348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004814 - arginine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006420 - arginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HGR0392602.1"
                     /translation="MNTKELIASELSSIIDSLDQEAILKLLETPKNSEMGDIAFPAFS
                     LAKVERKAPQMIAAELAEKMNSQAFEKVVATGPYVNFFLDKSAISAQVLQAVTTEKEH
                     YADQNIGKQENVVIDMSSPNIAKPFSIGHLRSTVIGDSLSHIFQKIGYQTVKVNHLGD
                     WGKQFGMLIVAYKKWGDEEAVKAHPIDELLKLYVRINAEAENDPSLDEEAREWFRKLE
                     NGDEEALALWQWFRDESLVEFNRLYNELKVEFDSYNGEAFYNDKMDAVVDILSEKGLL
                     LESEGAQVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKNEYQFAKSIYVVGQE
                     QSAHFKQLKAVLQEMGYDWSDDITHVPFGLVTKEGKKLSTRKGNVILLEPTVAEAVSR
                     AKVQIEAKNPELENKDQVAHAVGVGAIKFYDLKTDRTNGYDFDLEAMVSFEGETGPYV
                     QYAYARIQSILRKADFKPETAGNYSLNDTESWEIIKLIQDFPRIINRAADNFEPSIIA
                     KFAISLAQSFNKYYAHTRILDESPERDSRLALSYATAVVLKEALRLLGVEAPEKM"
     gene            36588..37034
                     /gene="argR"
                     /locus_tag="ACL3EZ_001012"
     CDS             36588..37034
                     /gene="argR"
                     /locus_tag="ACL3EZ_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0006525 - arginine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HGR0392603.1"
                     /translation="MRKRDRHQLIKKMITEEKLSTQKEIQDRLEAHNVCVTQTTLSRD
                     LREIGLTKVKKNDMVYYVLVNETEKIDLVEFLSHHLEGVARAEFTLVLHTKLGEASVL
                     ANIVDVNKDEWILGTVAGANTLLVICRDQHVAKLMEDRLLDLMKDK"
     gene            37085..39619
                     /gene="mutS"
                     /locus_tag="ACL3EZ_001013"
     CDS             37085..39619
                     /gene="mutS"
                     /locus_tag="ACL3EZ_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0030983 - mismatched DNA binding [Evidence
                     IEA];
                     GO_process: GO:0006298 - mismatch repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HGR0392604.1"
                     /translation="MAIEKLSPGMQQYVDIKKQYPDAFLLFRMGDFYELFYEDAVNAA
                     QILEISLTSRNKNADNPIPMAGVPYHSAQQYIDVLIEQGYKVAIAEQMEDPKQAVGVV
                     KREVVQVITPGTVVDSSKPDSQNNFLVSIDREGNQFGLAYMDLVTGDFYVTGLLDFTL
                     VCGEIRNLKAREVVLGYDLSEEEEQILSRQMNLVLSYEKESFEDLHLLDLRLATVEQT
                     ASSKLLQYVHRTQMRELNHLKPVIRYEIKDFLQMDYATKASLDLVENARSGKKQGSLF
                     WLLDETKTAMGMRLLRSWIHRPLIDKERIVQRQEVVQVFLDHFFERSDLTDSLKGVYD
                     IERLASRVSFGKTNPKDLLQLATTLSSVPRIRAILEGMEQPTLAYLIAQLDAIPELES
                     LISAAIAPEAPHVITDGGIIRTGFDETLDKYRCVLREGTSWIAEIEAKERENSGISTL
                     KIDYNKKDGYYFHVTNSQLGNVPAHFFRKATLKNSERFGTEELARIEGDMLEAREKSA
                     NLEYEIFMRIREEVGKYIQRLQALAQGIATVDVLQSLAVVAETQHLIRPEFGDDSQID
                     IRKGRHAVVEKVMGAQTYIPNTIQMAEDTSIQLVTGPNMSGKSTYMRQLAMTAVMAQL
                     GSYVPAESAHLPIFDAIFTRIGAADDLVSGQSTFMVEMMEANNAISHATKNSLILFDE
                     LGRGTATYDGMALAQSIIEYIHEHIGAKTLFATHYHELTSLESSLQHLVNVHVATLEQ
                     DGQVTFLHKIEPGPADKSYGIHVAKIAGLPADLLARADKILTQLENQGTESPPPMRQT
                     SAVTEQISLFDRAEEHPILAELAKLDVYNMTPMQVMNVLVELKQKL"
     gene            39766..41460
                     /gene="patA"
                     /locus_tag="ACL3EZ_001014"
     CDS             39766..41460
                     /gene="patA"
                     /locus_tag="ACL3EZ_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatA"
                     /protein_id="HGR0392605.1"
                     /translation="MLIQKIKTYKWQALASLLMTGLMVASSLLQPRYLQEVLGALLAG
                     KYEAIYSIGAWLIGVAVVGLVAGGLNVVLAAYIAQGVSSDLREDAFRKIQTFSYADIE
                     QFNAGNLVVRMTNDINQIQNVVMMTFQILFRLPLLFIGSFILAVQTLPSLWWVIVLMV
                     VLIFGLTAVMMGMMGPRFAKFQTLLERINAIAKENLRGVRVVKSFVQEKEQFAKFTEV
                     SDELLGQNLYIGYAFSVVEPFMMLVGYGAVFLSIWLVAGMVQSDPSVVGSIASFVNYL
                     SQIIFTIVMVGFLGNSVSRAMISMRRIREILDAEPAMTFKDIPDEELVGSLSFENVTF
                     TYPMDKEPMLKDVSFTIEPGQMVGVVGATGAGKSTLAQLIPRLFDPQEGAIKIGGKDI
                     REVSEGTLRKTVSIVLQRAILFSGTIADNLRQGKGNATLFEMERAANIAQASEFIHRM
                     EKTFESPVEERGTNFSGGQKQRMSIARGIVSNPRILIFDDSTSALDAKSERLVQEALN
                     KDLKGTTTIIIAQKISSVVHADKILVLNQGRLIGQGTHADLVANNAVYREIYETQK"
     gene            complement(41610..42053)
                     /locus_tag="ACL3EZ_001015"
                     /pseudo
     CDS             complement(41610..42053)
                     /locus_tag="ACL3EZ_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844241.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            42251..44017
                     /gene="patB"
                     /locus_tag="ACL3EZ_001016"
     CDS             42251..44017
                     /gene="patB"
                     /locus_tag="ACL3EZ_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatB"
                     /protein_id="HGR0392606.1"
                     /translation="MKTVQFFWHYFKVYKFSFVVVILMIVLATFAQALFPVFSGQAVT
                     QLANLVQAYQNGNPELVWQSLSGIMVNLGLLVLVLFISSVIYMCLMTRVIAESTNEMR
                     KGLFGKLAQLTVSFFDRRQDGDILSHFTSDLDNILQAFNESLIQVMSNIVLYIGLILV
                     MFSRNVTLALITIASTPLAFLMLIFIVKMARKYTNLQQKEVGKLNAYMDESISGQKAV
                     IVQGIQEDMMAGFLEQNERVRKATFKGRMFSGILFPVMNGMSLINTAIVIFAGSAVLL
                     NDKSIETSTALGLIVMFAQFSQQYYQPIIQVAASWGSLQLAFTGAERIQEMFDAEEEI
                     RPEKAPTFTKLQESVEISHIDFSYLPDKPILKDVSISAPKGQMTAVVGPTGSGKTTIM
                     NLINRFYDVDAGGIYFDGKDIRGYDLDSLRSKVGIVLQDSVLFSGTIRDNIRFGVPDA
                     NQEMVEVAAKATHIHDYIESLPDKYDTLIDDDQSIFSTGQKQLISIARTLMTDPEVLI
                     LDEATSNVDTVTESKIQHAMEVVVAGRTSFVIAHRLKTILNADQIIVLKDGEVIERGN
                     HHELLKLGGFYSELYHNQFVFE"
     gene            44156..44845
                     /locus_tag="ACL3EZ_001017"
     CDS             44156..44845
                     /locus_tag="ACL3EZ_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HGR0392607.1"
                     /translation="MARTVVGVAANLCPVDAEGKIIHSSVSCRFAEIIRQVGGLPLVI
                     PVGDESVVRDYVEMIDKLILTGGQNVHPQFYGEKKTVESDDYNLVRDEFELALLKEAL
                     RQNKPIMAICRGVQLVNVAFGGTLNQEIEGHWQGLPFGTSHSIETVEGSVVAKLFGKE
                     SQVNSVHRQSIKDLAPNFRVTAIDSRDQTIEAIESIDEHRIIGLQWHPEFLVNEEDGN
                     LELFEYLLNEL"
     gene            44849..45028
                     /locus_tag="ACL3EZ_001018"
     CDS             44849..45028
                     /locus_tag="ACL3EZ_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0392608.1"
                     /translation="MEHLVVLSFIFSKFLECGILRKRLNSDKNWRNSTKKLEKNEGKR
                     YDRKEEILEEEHVTY"
     gene            45015..46364
                     /locus_tag="ACL3EZ_001019"
     CDS             45015..46364
                     /locus_tag="ACL3EZ_001019"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004347 - glucose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HGR0392609.1"
                     /translation="MSHIKFDYSKVLDKFVAPHEVEYMQSQVTAADELIRKGTGAGSD
                     FLGWLDLPEKYDREEFDRILKAAEQIKSDSDVLVVIGIGGSYLGAKAAIDFLNHHFAN
                     LQTKEERKAPQILYAGNSISSTYLADLVEYVADKDFSVNVISKSGTTTEPAIAFRVFK
                     ELLVKKYGQEEANKRIYATTDRQKGAVKVEADANGWGTFVVPDDIGGRFSVLTAVGLL
                     PIAASGADIKALMEGANAARKDYTSDKISENEAYQYAVVRNILYRKGYATEILVNYEP
                     SLQYFSEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGTRIMFETVVRVDK
                     PRKNVLIPTLEEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGDVPNMYVTLPEQDAF
                     TLGYTIYFFELAIALSGYLNAINPFDQPGVEAYKRNMFALLGKPGFEELSKELNARL"
     gene            46488..47948
                     /gene="gltX"
                     /locus_tag="ACL3EZ_001020"
     CDS             46488..47948
                     /gene="gltX"
                     /locus_tag="ACL3EZ_001020"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004818 - glutamate-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HGR0392610.1"
                     /translation="MSKDIRVRYAPSPTGLLHIGNARTALFNYLYARHHGGTFLIRIE
                     DTDRKRHVEDGERSQLENLRWLGMDWDESPESHENYRQSERLDLYQKYIDQLLAEGKA
                     YKSYVTEEELAAERERQEVAGETPRYINEYLGMSEEEKAAYIAEREAAGIIPTVRLAV
                     NESGIYKWHDMVKGDIEFEGGNIGGDWVIQKKDGYPTYNFAVVIDDHDMQISHVIRGD
                     DHIANTPKQLMVYEALGWEAPEFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYL
                     PEAVFNFIALLGWNPGGEDEIFSREELIKLFDENRLSKSPAAFDQKKLDWMSNDYIKN
                     ADLETIFEMAKPFLEEAGRLTDKAEKLVELYKPQMKSVDEIIPLTDLFFSDFPELTEA
                     EREVMTGETVPTVLEAFKAKLEAMTDDEFVTENIFPQIKAVQKETGIKGKNLFMPIRI
                     AVSGEMHGPELPDTIFLLGREKSIQHIENILKEISK"
     gene            47962..48393
                     /locus_tag="ACL3EZ_001021"
     CDS             47962..48393
                     /locus_tag="ACL3EZ_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000355927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HGR0392611.1"
                     /translation="MDIWEKMYEEAQKLYNPHEVSDFVYANHVVAAVEAGDGQIFTGF
                     CMEGTCGVFHLCAERATLFNMYQFSGQTKVKKVLAFRDKPPYGGSSAMPCGACREFLL
                     ELNAENKDAEFMMDYNIRKTVKVAELIPYWWGEERASKFNE"
BASE COUNT        14281 a         9206 c        10536 g        14458 t
ORIGIN      
        1 ctttgatttt cattgagtat aaaaagatct tgggaaaaga ctcaatttca gtagaaaagg
       61 aagtaaatct tcccacaata aaacgcatag tatcaagttt tttcaatacc tgatagtatg
      121 cgtttttgct tttaacgact ctttgcccag tctcttattt ttcgataatt ttgtgggcga
      181 tcaattgacg gtaacaaatt tgtttattgt ttttattatc attaataatc tggagaatag
      241 tttcaaggga aacacgacca agctctaaac tattgatatc gacataggct gccaagttga
      301 gcttgggatt aaccgagtca aagctgagaa cagggacatc cagctggtgt ttggcaatat
      361 agttacaaac accttcagct aggaggctat cggttgtgat gatagcatca atttgtggat
      421 cgtgcttgaa taatcgcttg ctaaatttat agcccttttc ttccagaaac tcgtcggcaa
      481 agtagatgcg attgttgtca gtggtaagtt tgtaatgttt aagcgcctgt tcatagcccg
      541 ttaaacggtc tttggtcacg aagagctttt tacttcctcc gataaaggca atgcgtttgc
      601 agcctttttt gatgaaatat tcagtcgcat caaaaccagc ttgaacattg tcgttgtcga
      661 caagtgggat gaaaggagat agagatttac ctaagataag gaaggggaac tgttcttctg
      721 cgacgagttt tacgagaggg tcttcttctt gggcatagag aaagattagc ccatctacac
      781 gcttgccgta gaccatttgt gaaatagcgt tgagacgctc cttctcatct ttccctgttg
      841 ctatttgaat ggcatagtgg ttttcagatg cgacttgaga gatgccacgt agaaccgatg
      901 gaaagaaagg attctggtag aaggcgtctg agtcatcagg aagaactaat ccgataacct
      961 gagtatagct gcttaccaag ctacgagcgt taaggtttgg gtggtagttg agttccttca
     1021 tagctttgcg aacgcgtttt tttgtttcgt cgctaatggt tgatttattt tgaataacac
     1081 gggttacggt tgaaggcgaa acaccagcag ccttggccac gtctttaatc gtaacgggca
     1141 taaaaatctc ctatttatgg taatttggat cacggaaatg tgttttataa aagatagtga
     1201 ccagatacag aacaaaaaga atattttgta cagtaatcag ggttgtcata ttttggccaa
     1261 ataatcccaa aataagtgta atcagagtcg gcaatcctaa acagttcaag ataaagtgat
     1321 agcactcttt aaaggttcta aatgaaaaga ggcgtgattt cttagtgata taaaggagaa
     1381 gactagctcc tagagagacg ataaagaaat tcaaaccaaa gaggaagctc gcaccgagaa
     1441 ctaggaagag gctgatatag acacgatttt gttggtacca gtctttagaa attgcttggg
     1501 tcaagctgtc tttgcttttg aaactctcag tctgaatggc tcggtaagag atgcgggtca
     1561 gttccttgct ttccttgctg atgactagtt catttgtatc gaaatgcagt tgcaagtcct
     1621 taggtaattc cttgatttga cctggaccaa tcacaacaga aggggcttga ctagctgttc
     1681 cagtataagt taatgtgcca tcgacaattg tagcatgttc agagagatcc tggacaacct
     1741 catttgtcag aggttcatag acattatcga taaaagtttc tagcggatag gtctcttggg
     1801 agctgttttg gatagcaatg ggtaccatag acaagctgat aaggaagata ctggtaaaga
     1861 gaagttgaaa ccagttgagc tcgaaacgtt tggacagggg cttacgaaac ccccaaatac
     1921 ttgaaaaata ggaaaatgga tatggaagca taggtatctt tctaaaaggt gttttctata
     1981 tgagtattat tatatagaga aatgcgcttt atttcaagtc tagggggtaa attgcttgct
     2041 acaaggatat tatttacagt gacaatcgct aatagtcaat gaaaatcaaa gtgcaaacca
     2101 ggaagctagc tgcaggttgc tcaaagcaca actttgaggt tggagataaa gctgacgtgg
     2161 cttgaagaga ttttcgaaga gtataaaatg aaaaagggtg gcggggataa attatccctt
     2221 gtcgccacca cttgtaagtc ctgaaacaaa gttcttttgt aggaagaaga agagaataca
     2281 gattggaagg gcgatgagga tagcacctgc tgagaagtag gcaatcttca agtttttcgc
     2341 attgttaacg aaggtttgga gacctacggc aacagtaaag tattctttct cacgaagcaa
     2401 gaaactagag aggatgtagt ccccgaaagg tcccatgaag gcccagagag cttgtacggc
     2461 aaccattggg cgaacaagtg gtagaacaat ttgccagaag cggcggaagt gtcctgcacc
     2521 gtctagtttt gcagattcgt ctaaagacat tggcactgta tcgaagtagc ctttcatgag
     2581 ccaagcattc atcgggatac caccaccaac gtagaggaag atgaggaacc agttgtggtt
     2641 aagggcgttc aacataagcg ccataacgaa gaaggctgtc aaagcggcca tagttggcac
     2701 catttggatg atcaagaaga agaccaaact ttgtttacga gccaagaagt tgtaacggct
     2761 gtaagcataa ccagcaagta cgatgatact tgtttgaaca gccatggtaa ttaaggcgat
     2821 aatcaaagtg ttgaggtacc aagtaccgta caaggtttca gtgaagaggc ctttaaagtt
     2881 atcaaaattg aggtcgatat tagtatctag tttaaaggct gagacgttac ctgctttaaa
     2941 ggctgacatg atggtaatca acagtggata gataattaca attgatagac caatcaggta
     3001 aaggtaagta aggctttgag tcagtctacg tttgagttta attgagttat tcatcttaga
     3061 cgtcctccat atcaaatgcg tgtagtttct tgaatgcgat catagagatt gagatgacaa
     3121 tgatagagat aatcaaggta acagctgccg ccattgagta ttgaggagat gtacctgttg
     3181 tcaaacggta gatccatgag atcaagatat cggttgaacc agctccacct ccgacactac
     3241 caggtcctcc accattgaag aggtacatga tagagaagtt gttaaagttg aaggtgtatt
     3301 ggctaatcaa agtaggtgcc gcaacagcca aaatcattgg gaaagtgatg ttgcggaatt
     3361 tttgccaagc gttggcaccg tcaatataag ctgcttcgta aaggtcgtta ggaatagatt
     3421 gcaagatacc caaagtcaaa acgtagatgt atgggaatcc gagccaacct tgcatcataa
     3481 tcaaggcaat cttagtccaa gttgggtctg ttttccaagg aataagagct ccatcaagga
     3541 aaggaaggaa tttagccaag attggcaata cttgagtgtt gatagcaccg acactatcgt
     3601 taaacatgtt tgagaatgtc aagatagtga tgaaggctgg gacagcccaa ggaagaagga
     3661 aaataacacc aaagatacgt tttcctttga taaatggttg gttggcaatg atagctgtga
     3721 agataccaat tacgatttgt aaagtagaag ctgccaaagc ccaaatgata gtccaagaaa
     3781 gaacagaacc aaaggcagaa cggaaggtac tcaagctcca aatgtttgta aagttggtca
     3841 aaccaaccca gtccaacaac ttgtttggtg gcaagtgttg gaagtcgtag ttggtaaagg
     3901 cgatcatcaa ggttacgata actgggaaga taatcgcgaa ggtcatggca acataagatg
     3961 gaatgatcaa gaggtaaggg aagccatttt cataaatccc tttgatcatg tctttgagtg
     4021 tgcgtggaac tggaattcca ttgttaatgc gttttgcaat cgtatgtgca tctttgatat
     4081 ttgagaaata aaagagtaca taaacgatta caaagattag atggaaggca ccacgaatca
     4141 gcataaagag ggaattatca cgacctggtt tgtcaccaag agtgatgagg ttgctcaatt
     4201 caggggttgc aagtgctagg aagtaaagga caaatacgat ggttacacca aggaagataa
     4261 aacctttggc tttttgttta ttgtaaatct gtcctaaccc aggaatgata gacagcaggg
     4321 ctgctttact aggttgttgc ttttccatat taactccttt cataggatac tactttttta
     4381 taagaaagct aaattatttg tgtctctatt gataaattca aagggggatt tgatttccac
     4441 cccccttgaa caaatttttt attcaccaaa tttttgtttg attgtttctt tgatcaatgt
     4501 tacagcatcg ttagcagctg ttttagcatc tttttgacca cttacagcat caaagagcat
     4561 atttttcgct ggatcccaaa ctgcagacat ttgagagatg tttggcagtg gttgagtgtt
     4621 cttgaactgt ttgataacag ctgttgtcaa ctcatcgttt ttaccttcag cgtatgaacg
     4681 agcctcagta ttagctggga tttcgttagt cttatcatat aatacttttt gttgttcagt
     4741 tgcaacaagg aagtctacaa atttttgaga agcttcaagg ttcttaacgg cttgaggaat
     4801 gacccaagct ttaccaccac cgaatgcagc atattctttt ccatttggaa gagttgggat
     4861 agttgcaact ccgtagttta ctttagcatc tttaaaggct tgagctttcc aaggtccgtc
     4921 gatgatagca gctgttttac cttcttgaaa ttgagtttgg attaagtttc cagcaccttc
     4981 tgtatcttgc atacctttag gccatttttc gtaccaagat ttagcgtagt tgatacctgc
     5041 gatagaaccg tcgtttgcaa gaccgatgtc tttagcgtct ttaccgtttt ggccaaagac
     5101 gtaagcaccg ttaccggcaa gaagtccata tgtatagtag aagtttgtcc agtcagctag
     5161 gaaggcagta gttttaccat cttcaccagc gaatgcgtat ttgctatctt tagcaaggtt
     5221 ttccaagtca gcaaatgttt ttggagcatc tttcaccaag tctttgttgt agtacataac
     5281 aagtgactcg ataacggcag gagcaccgta aactttacca ttagcagctg ttacaagaga
     5341 tttagttgtg tcgtctgttt tagcaccatc gctcaatttc acttctgaaa gttgtccgtc
     5401 agaaccaagg ctacctacac ggtcgtatgg agccatcata acatcaggga cattaccaga
     5461 ttggttgtca agagaaagtt tatcaagacc tcctagagca tcaccagttt taagagtgac
     5521 ttttactcca gcttcttttt cataagcttt agcaacctct tcaatatagc tcttatatcc
     5581 ctcgtctaca tatacagtga gttctttgac ttcagatgaa ccagaatcag caggcttatc
     5641 agcagttttg cttccgcaag ctaccaaaag caagctagca agtgtagcag ttccaagcac
     5701 cgcagtgctc ttcataaatt tagatgacat agtgtattcc tcccaaagaa tagcaagttt
     5761 tattgataag gaaacgcaaa cgttttcctt tatgagctta gtatagcaca aatagaaaac
     5821 ggttgcaagt attttttgta aaaattttaa aaaattttta agcttgattt gatagcataa
     5881 ttttgcattt taatagaaga aaagtatgaa atagataaga atacagtatt tttaataaaa
     5941 atatatggaa tctgtctaaa gagggaaatc aggaggggct acctccctgt ttctaatccc
     6001 tatctatttt ctatagacgt ttgtgctttg ttgcatataa attcaagctc cctaaggagg
     6061 ttttgtactt tgtagactgt ctcgtgagag tcaaacttta ggattagata gttttaagtt
     6121 atctttgcta aaatgagtta gtctccttaa aaataatcaa aaaagttttt taaaaacgct
     6181 tgcaattatg cttgaaaagg agtatactta taagtaacgc aaacgtttgc gtctgcaaaa
     6241 tacgcaacgt tccattattt taacacacga ggtgctatta tgaaaaaacg tcaaagtggt
     6301 gtgttgatgc acatctcttc tcttccagga gcttacggaa tcggatcatt tggtcaaagt
     6361 gcttacgact tcgttgattt cttggtccgt acaaaacaac gttactggca aatccttcca
     6421 ttaggagcaa ctagttacgg ggattctcct taccaatctt tctcagcctt cgcaggaaac
     6481 actcatttta tcgatttaga tatcttggtg gagcaaggtt tgttggaagc aagtgacctt
     6541 gaaggagttg actttggtag cgatgcgtct gaagttgact atgctaaaat ctactatgca
     6601 cgtcgtcctc ttttagaaaa agcggtgaaa cgtttctttg aagtcggaga tgttaaagat
     6661 tttgagaaat ttgctcaaga caaccaatca tggcttgagc tctttgctga gtatatggct
     6721 atcaaagagt attttgacaa tcttgcttgg actgaatggc cagatgcaga tgctcgtgct
     6781 cgtaaagctt cagcacttga aagctatcgt gagcaattgg cagacaagtt ggtttaccac
     6841 cgtgtgactc aatacttctt cttccaacaa tggttgaaat tgaaagctta cgctaacgac
     6901 aaccacatcg aaatcgttgg ggacatgcca atctacgtag cggaagattc aagtgatatg
     6961 tgggcaaatc cacatctctt caaaacagat gtcaatggta aggctacttg tatcgcagga
     7021 tgcccaccag atgagttttc tgtaactggt cagctttggg gtaatccaat ctatgactgg
     7081 gaagcaatgg acaaagacgg ctacaaatgg tggattgaac gcttgcgtga aagcttcaaa
     7141 atctacgata tcgttcgtat cgaccacttc cgtggcttcg aatcttactg ggaaatccct
     7201 gctggttccg atacagcagc acctggtgag tgggtgaaag gtccaggcta caagcttttt
     7261 gcagccgtta aggaagaact tggtgagcta aacatcatcg cagaagacct tggcttcatg
     7321 acagatgaag tgatcgaatt gcgtgaacgt actggcttcc caggaatgaa gattcttcaa
     7381 tttgccttca acccagaaga cgaaagcatt gatagcccac acttggcacc tgctaactca
     7441 gttatgtaca caggaacaca cgataacaat acggttcttg gttggtaccg taatgagatt
     7501 gatgatgcga ctcgtgagta catggctcgt tacacgaacc gtaaagaata cgaaacagtg
     7561 gtacacgcta tgcttcgtac agtattttca tcagttagct ttatggcaat tgcaactatg
     7621 caagatttac tagaattgga tgaggcagct cgtatgaact tcccatctac ccttggtgga
     7681 aactggtctt ggcgtatgac tgaagatcaa ttgacaccag ctgtcgagga aggtttgctt
     7741 gacttgacaa caatttatcg ccgaattaat gaaaatttgg tagatttaaa gaaataagac
     7801 aataatcagg agacaactaa acatgttatc actacaagaa tttgtacaaa atcgttacaa
     7861 taaaaccatt gcagaatgta gcaatgaaga gctttacctt gctcttctta actacagcaa
     7921 gcttgcaagc agccaaaaac cagtcaacac tggtaagaaa aaagtttact acatctcagc
     7981 tgagttcttg attggtaaac tcttgtcaaa caacttgatt aaccttggtc tttacgacga
     8041 tgttaaaaaa gaacttgcag ctgcaggtaa agacttgatc gaagttgaag aagttgaatt
     8101 ggaaccatct cttggtaatg gtggtttggg acgtttggct gcctgcttta tcgactcaat
     8161 tgctactctt ggtttgaatg gtgacggtgt tggtcttaac taccactttg gtcttttcca
     8221 acaagttctt aaaaacaacc aacaagaaac aattccaaat gcatggttga cagagcaaaa
     8281 ctggttggtt cgctcaagcc gtagctacca agtaccattt gcagacttta ctttgacatc
     8341 aactctttac gatattgatg ttactggtta tgaaacagcg actaaaaacc gcttgcgttt
     8401 gtttgacttg gattcagttg attcttctat tattaaagat ggtatcaact ttgacaagac
     8461 agatatcgct cgcaacttaa ctctcttcct ttacccagat gatagtgacc gtcaaggtga
     8521 attgctccgt atcttccaac aatacttcat ggtttcaaac ggtgcgcaat tgatcatcga
     8581 cgaagcaatc gaaaaaggaa gcaacttgca tgaccttgct gactacgcag ttgtccaaat
     8641 caacgatact cacccatcaa tggtgattcc tgaattgatt cgtcttttga ctgcacgtgg
     8701 tatcgagctt gacgaagcaa tctcaattgt tcgtagcatg actgcctaca ctaaccacac
     8761 aatccttgct gaggcgcttg aaaaatggcc tcttgaattc ttgcaagaag tggttcctca
     8821 cttggtacca atcatcgaag aattggaccg tcgtgtgaag gcagagtaca aagatccagc
     8881 tgttcaaatc atcgatgaga gcggacgtgt tcacatggct cacatggata tccactacgg
     8941 atacagtgtt aacggggttg cagcacttca tactgaaatc ttgaaaaatt ctgagttgaa
     9001 agccttctac gacctttacc cagaaaagtt caacaacaaa acaaacggta tcactttccg
     9061 tcgttggctt atgcatgcta acccaagatt gtctcactac ttggatgaga ttcttggaga
     9121 tggttggcac catgaagcag atgagcttga aaaacttttg tcttatgaag acaaagcagc
     9181 tgtcaaagaa aaattggaaa gcatcaaggc tcacaacaaa cgtaaattgg ctcgtcactt
     9241 gaaagaacac caaggtgtgg aaatcaatcc aaattctatc tttgatatcc aaatcaaacg
     9301 tcttcacgag tacaaacgcc aacaaatgaa cgctttgtac gtgatccaca aataccttga
     9361 catcaaagct ggtaacatcc ctgctcgtcc aatcacaatc ttctttggtg gtaaagcagc
     9421 tccagcctac acaatcgctc aagacattat ccatttaatc ctttgcatgt cagaagttat
     9481 tgctaacgat ccagcagtag ctccacactt gcaagtagtt atggttgaaa actacaacgt
     9541 tactgcagca agtttcctta tcccagcatg tgatatctca gaacaaatct cacttgcttc
     9601 taaagaagct tcaggtactg gtaacatgaa attcatgttg aacggagctt tgacacttgg
     9661 tactatggac ggtgctaacg tggaaatcgc tgagttggtt ggagaagaaa acatctacat
     9721 cttcggtgaa gattcagaaa ctgttatcga cctttacgca aaagcagctt acaaatcaag
     9781 cgaattctac gctcgtgaag ctatcaaacc attggttgac ttcatcgtta gtgatgcagt
     9841 tcttgcagct ggaaacaaag agcgcttgga acgtctttac aatgaattga tcaacaaaga
     9901 ctggttcatg actcttcttg acttggaaga ctacatcaaa gtcaaagagc aaatgcttgc
     9961 tgactacgaa gaccgtgacg catggttgga taaagtcatc gttaacattt ctaaagcagg
    10021 attcttctca tctgaccgta caatcgctca gtataacgaa gacatctggc acttgaacta
    10081 atactcttcg aaaatctctt caaaccacgt cagctttatc tgcaacctca aagcggtgct
    10141 ttgagcaacc tgcggctagc ttcctagttt actctttggt tttcattgag tataagatac
    10201 aaatttatac taatacattt tgtaaaaaag cgagtttcga ttgaaattcg cttttttaaa
    10261 tgctgtagat ttgggtcaat cttgtctaaa aatagggaaa tcctagatac agtgaagact
    10321 ttaaatgctg gtttttactg tcctcagcct tatatttttt cgtagttgat tacctcacac
    10381 ctcttgtatt cgcttacata aagtattata atataattgt aggaaagaag gtgtttttat
    10441 gatatacaca cttaaattgg tgttgtttat tacctttctt gtaataagct tgttacctga
    10501 taagattttt ggaaaaaata aaaaaatttg gaaaatagtt tttgcaatat tgacggcagt
    10561 ggcagcattg tcatttatgt actaagttat tttaagaatg tagggaaata aaccctacat
    10621 tctttttagt tttttctgtt ttctaaattc tatttatcca agcgcttcaa catttcttgc
    10681 ttcttcgctt caagttctgc acgcttttct tcgatttcgg catgtttttt ctcgagttca
    10741 gaacaacttg caccattgct aaattctttt cgccatcagg agatagggtg agtcgacatg
    10801 tctattactc acccaaagca gtcctacaaa gcaggaattt tctgttactt ttttggaaat
    10861 agtaacgttt atacagcttt gacacttcgt atcaaagcgc caaacacact ccgagggatt
    10921 tacagaaagc agaaaaggaa tgatctggta taagatcatt ccttttctct ctttttcttt
    10981 aagtaattat atacaatgta cgacgaagtc gtcattgcaa tgctgatcca ccacctaaag
    11041 ggaactttaa acaacattga taagataaag aatataaaca acgaaaatac gttataccca
    11101 attaatttta ttgtatatct catgattaaa agttaatcct tccgttgtta ggaatggcat
    11161 catttttatc ccataattgt gctaaataag tccccggtga taataaattc atagcggatt
    11221 ctaaagcaac atcatttaca aaccaactac ctagatatct agaaattgct gaacgaatag
    11281 cactttttgc tgcatgtttt ccttttactt taattagatt tgcaaggcct gcagtagttc
    11341 ctcctaatgc taaagctatt gtagtatcta atagagcacc catttgatta actgtaatac
    11401 cttgccaagc tgctctaaat ggagagtatg taggtgggat tgtataatcg ccttgtaatt
    11461 gtcggttaat tacttctttg atccattgtt gtgagacgtc tggatgaaaa gattggattt
    11521 cgtttgcaag tgtattgatt tgttcttctg ttagagaagt gacaggttga agttccatat
    11581 ttgtttcaat ttgcgatact tgttcagaag cgtatacagc tgaaacactt ggaatcgctg
    11641 atacaattaa cacaattgac gtcaaaaaaa ccgaaataaa tttcattaat ttgttcatga
    11701 gcttttctcc tttttatttg tatctgctta cattttatta tatactgtta ttatagtcaa
    11761 gaaaaatatg ctattatgtt aaaaaaatat ttttcaaaat ataaatggac ggatttattt
    11821 tggattttat ttgttatttt gacctgcctc tatattggta accatgattt gtttactctc
    11881 aatcatcaag aattctcttt tcgtggtagc ttttggggtt tggtactggc cttatatcac
    11941 ttattgttca ttgataagtt tgtaatttcg aatcgaaaat aaagattaga actatgattg
    12001 actggctact tttaatattg attttggagg aagattttgt ctctattatt tattatttta
    12061 aatttatcta ttttgtacaa tatctattct ttgagacggg agaaatcgaa atacttgatt
    12121 tatacggcct atatcatatt tggggtaaat gtagtatatg gtattcaatg gttattaaga
    12181 gaactgattt caactatttc cccttaatgt gtatggaaac tataacaaag cgcataagat
    12241 taaggtttgt gtacctgttc ttatgcgttt ttgtaatatt gaagattttc ggtaagtttt
    12301 atacctttgg gaagtctagt ttagaatgct ttcccaacca gaatctctgc ttcgatggta
    12361 atctctgtca gttggctcca gtcaatcttg ctctggtcaa catgaaagag gagaggagtc
    12421 atactgagta gggcttggag ttgttctgct gtgatagtct tagtcagaga ggcagtttga
    12481 ctagatagga tggtaaagtg ttcctggaaa tgctccttga tatcttggtt agaatactcc
    12541 ttgtttgtca gctggtcctg tactctttga cggatttctt tgaggtgatt ttcagttggg
    12601 ataaccttta tcaagatacc gtctttggat aaaacgcgac gaaattctcc atagttggca
    12661 ggtgagaaga tatcaagcag aatatccatg ttagcgtctt ttataggaag tcgtgccaag
    12721 tcgccaacga accaattgac tgcccagttg ggttcacttt tagcagcgat ttggactgaa
    12781 tctttggaga tgtcaaaggc atagaaagtt ttttcagagt gactttcttg tagtttgcga
    12841 gaatagaatc cttcaccaca accgatatcc aaaattgttg tggtagtttt tgagcttgca
    12901 agcaagtcag atacagcatc taagatagct tggtaaaagc cggcttctag gatttgttga
    12961 cggttttgaa aattttcctt gtcatagtta gcagattgct tgatttgagg tgctagattg
    13021 acatagccaa atttcgccaa gtcaaaagaa tgacggttgc agcacttgaa attagtctct
    13081 aacagagtca gattttcttg acagatagga caggcaaagg cagtcgcaga agcaaaacgc
    13141 tgaagtttgg gcttgagatt tgtattcata gtttaagtgt atcaaaagag gcaaatgaaa
    13201 gcaactttag gaataagtag atgggagatt cagtagaaat aaaactaatt ctccaattta
    13261 tagaatgaaa ttgcttttat atctaaattg ctatataata atgataagga ggaaataagt
    13321 atgttaaaag aagtattaac cgttgcaaaa gttgcgaaaa aatcttcatt atttttgggt
    13381 ggtgtcgcat ttggtaccct tggtttgaaa atcttagcaa gtaaggaagc taaaaaaggt
    13441 tattctaaag ctttggctaa ggcttacaag ttgaaagacg agctagatgc atctgtttct
    13501 gttgtgaagc aacatggaga cgatgtcttg caagatgcca aatatttgta cgagcaagag
    13561 aaaaaagaag agcaattaga tagccttata ggtgaataat atgtctttta aagtgctaca
    13621 tagaggatac caacatatcc gactatcatc ttctttttca cttaccttgg atattcaaga
    13681 ctatcttcgt tccttggcga gagatgaaaa ggggattgag tctatccagt tttacatgga
    13741 tcaacagcac tttactctac gcataaaaga aggcttttct gtattagata atgcagaagc
    13801 ctttttaaaa agaattgata aagggaaagt ttctgagttg atgactcttc ccattcgtag
    13861 agaagagagt gcttattcta ttgtttcagg tgcagcggtt aagcgtgtac tttttcgtag
    13921 ttttgtgccg tatcctattc gctatatatg gacttgttat caggctttgg gttatattag
    13981 agaagcctat caaacactag cgcgtaagga actaacgatg gaagtcttgg actgttcggc
    14041 tattttattg tctttgttta tgaaccaatc caagacagct agcaatatca tgtttatgct
    14101 tgatttgggg aatcatttag atcagtggtc cttgaaaaaa actgcaacag atttagaaca
    14161 gagtcttctt gcaaaagaga gcgatgtatt cctagtacag ggcgatacgg ttgttagtat
    14221 caagagttcc gatgttcaaa taggagatgt cttgatctta tctcaaggaa atgaaattct
    14281 gtttgatgga caagtagttt caggtttagg tatggtcaac gaaagttcct tgacaggaga
    14341 gagttttcca gttgaaaaaa gagagtctga tttggtttgt gcaaatacag tattagaaac
    14401 tggagagtta cgcattcgtg taacagataa tcagatgaac agccgtattt tacagctgat
    14461 taagttgatg aagaaatctg aagaaaacaa gaaaacgaaa caacgctatt tcatcaagat
    14521 ggcggataaa gtcgttaaat ataatttctt gggggctggg ctgacttacc tattgacagg
    14581 ttctttttct aaggctattt ctttcctatt ggtcgatttc tcctgcgctt tgaaaatctc
    14641 tactcctgta gcttatttga cagttatcaa ggaagggttg aaccgtgaaa tggtgattaa
    14701 ggatggagat gttctggaga aatatctgga agttgatact ttcttgtttg ataagacagg
    14761 aacaatcaca actagttatc ctatagttga aaaggtgtta ccttttggag actatagtga
    14821 ggaagatatt ctcagaatca gtgcctgtct tgaggaacac atttatcatc ctattgctaa
    14881 tgccatcgtc aagcaagctg agatagaggg aattgaacat gaggaaatgc atgggaaact
    14941 ccaatatatc gcaagcaagg ggatcaaatc tcatatagat ggccaaccag ttcttattgg
    15001 gaattatgtc ttgatgcagg atgagcagat tcatatcagt tcagaacaaa atgctttaat
    15061 tgaagagtac aagagtcact acaatctctt attcttggct tatcaaaatg aattgattgg
    15121 aatgttctgc attcatactc ctttgagaaa agaagcaaaa acagccttgg ataaacttaa
    15181 ggcacagggg aaaaaattga ttctggcaac aggagacacc ttgattagga cagaggaatt
    15241 agtcaaagat ttgccctttg atcaggtcta tacagacttg aaacctgatg ggaaatttga
    15301 gttagtagag aaactgcaga aagcaggtca cactattttg atggttggag atggattgaa
    15361 tgactcagcg gctttaactc tatcagatat cggtgtggtg atgaatgaga gtgcagatat
    15421 ttctaagcag atgagtgata tcttattgtt agataatcgt ttggatttct tccaagagtt
    15481 ggattcgtta tcatcatctt tgcaaacact catcaagaaa aatattcaag ataccgttgt
    15541 cgtaaatagt agtttgattg gctttggctt atttaattgg ctcagtcctt caaatctctc
    15601 tatcttacat aatctaacaa ccttgcgcat tgtcctgcgt agcctgtcta ttaaaaatag
    15661 atagatgaga gttattaaca gcaaaaagga gttacctttc tcgaggttaa ctcctttgtt
    15721 tatagataaa tgttgaatag tttagtaagt caatacaaag tattttttct tcccacgacg
    15781 gataacagtc agttcatttt ctaacttatc agcgtcactc aagacatagt caaggtcttg
    15841 gatgcggtcg ccgtttacgt agatggctcc gttttggacg tcttcacggg cttggcgttt
    15901 tgagttaact ataccagatg agacgagcag ttccacgata ttgttgtgtt cgtctgcctg
    15961 tacttggtag tttggcacac cacgaagtcc ttgtttgagc tctttgacag aaaggttttt
    16021 gatgtttcct gcaaagagtt gctcagtgat gttaagtgct tctttgtagg attcttctcc
    16081 gtgaacaagt gtaacaactt cacgagccaa gactttttga gccaagcgtt cgtgtggcgc
    16141 tgcttcaaat tgtttgcgaa tatcttcaat ctcatcaagt gacaagaaag taaagatttt
    16201 caagaagcga acagcgtcag cgtccatcac gttcatccag aattggtaca tttcgtatgg
    16261 agaagtcttt tcgggattga gccagacggc atttccttct gatttaccaa atttcttacc
    16321 agttgcatct gtgattagtg gaacagtgat aacgtgacca gtcttgtccg ccttacgacg
    16381 aagcaattcg gtaccagctg tcatatttcc ccactggtca gaaccaccga tttgaagagt
    16441 gacattatgg tcttggttaa ggacgaagaa gtcataccct tgcatgattt ggtaagcgaa
    16501 ctcagtgtaa gaaattcctg tttcgatccg ttttttaaca gattccttac tcatcatgta
    16561 gttgaccgtg aagtattttc caatatcacg gaggaagtca atgaagctga tgctgccaaa
    16621 ccagtcgtag ttgttgacca tgacagcctt gttttcgcca ttttcaaagt caagaaaacg
    16681 agaaagttgt ccttggatag acttgaccca gccatctact gtgtcttttg tttggagact
    16741 acgttcagca tctttgaagg acggatctcc gatgagacct gtagcaccgc caacgagcgc
    16801 ataaggtttg tgacctgcta gttgcaagcg acgacttgtc aagattgcga caaggtggcc
    16861 taggtgaagg ctgtcagcag ttggatcgta gccagtatag taagaaactt gaccttcttc
    16921 tagggcttta cgcaaagctt cttcatcagt cgtttgaaat atcaaaccac gctcttttag
    16981 ctcatcaaaa atgtgcatgt gtcttttctc ctttttaaaa ttattgtttc tacctattgt
    17041 atcacaaact tgggcaatag cctagcagaa tagggaagaa agtggctatt ttattgaaaa
    17101 tttccctttt gtggtataat agatagagtg aggaaatcca tgcaaaatca attaaatgaa
    17161 ttaaaacgaa aaatgctgga atttttccag caaaaacaaa aaaataaaaa atcagctaga
    17221 cctggcaaga aaggttcaag taccaaaaaa tctaaaacct tagataagtc agccattttc
    17281 ccagctattt tactgagtat aaaagcctta tttaacttac tctttgtact cggttttcta
    17341 ggaggaatgt tgggagctgg gattgctttg gggtacggag tggccttatt tgacaaggtt
    17401 cgggtgcctc agacagaaga attggtgaat caggtcaagg acatctcttc tatttcagag
    17461 attacctatt cggacgggac ggtgattgct tccatagaga gtgatttgtt gcgcacttct
    17521 atctcatctg agcaaatttc ggaaaatctg aagaaggcta tcattgcgac agaagatgaa
    17581 cactttaaag aacataaggg tgtagtaccc aaggcggtga ttcgtgcgac cttggggaaa
    17641 tttgtaggtt tggcttcctc tagtgggggt tcaaccttga cccagcaact aattaaacag
    17701 caggtggttg gggatgcgcc gaccttggct cgtaaggcgg cagagattgt ggatgctctt
    17761 gccttggaac gcgccatgaa taaagatgag attttaacga cctatctcaa tgtggctccc
    17821 tttggccgaa ataataaggg acagaatatt gcaggggctc ggcaagcagc tgagggaatt
    17881 ttcggtgtag atgccagtca gttgactgtt cctcaagcag catttttagc aggacttcca
    17941 cagagtccca ttacttactc tccttatgaa aatactgggg agttgaagag tgatgaagac
    18001 ctagaaattg gcttaagacg ggctaaggca gttctttaca gtatgtatcg tacaggtgca
    18061 ttaagcaaag acgagtattc tcagtacaag gattatgacc ttaaacagga ctttttacca
    18121 tcgggcacgg ttacaggaat ttcacgagac tatttatact ttacaacttt ggcagaagct
    18181 caagaacgta tgtatgacta tctagctcag agagacaatg tctccgctaa ggagttgaaa
    18241 aatgaggcaa ctcagaagtt ttatcgagat ttggcagcca aggaaattga aaatggtggt
    18301 tataagatta ctactaccat agatcagaaa attcattctg ccatgcaaag tgcggttgct
    18361 gattatggct atcttttaga cgatggaaca ggtcgtgtag aagtagggaa tgtcttgatg
    18421 gacaaccaaa caggtgctat tctaggcttt gtaggtggtc gtaattatca agaaaatcaa
    18481 aataatcatg cttttgatac caaacgttcg ccagcttcta ctaccaagcc cttgctggcc
    18541 tacggtattg ctattgacca gggcttgatg ggaagtgaaa cgattctatc taactatcca
    18601 acaaactttg ctaatggcaa tccgattatg tatgctaata gcaagggaac aggaatgatg
    18661 accttgggag aagctctgaa ctattcatgg aatatccctg cttactggac ctatcgtatg
    18721 ctccgtgaaa atggtgttga tgtcaagggt tatatggaaa agatgggtta cgagattcct
    18781 gagtacggta ttgagagctt gccaatgggt ggtggtattg aagtcacagt tgcccagcat
    18841 accaatggct atcagacctt agctaataat ggagtttatc atcagaagca tgtgatttca
    18901 aagattgaag cagcagatgg tagagtggtg tatgagtatc aggataaacc ggttcaagtc
    18961 tattcaaaag ctactgcgac gattatgcag ggattgctac gagaagttct atcctctcgt
    19021 gtgacaacaa ccttcaagtc taacctgact tctttaaatc ctactctggc taatgcagat
    19081 tggattggga agactggtac aaccaaccaa gacgaaaata tgtggctcat gctttcgaca
    19141 cctagattaa ccctaggtgg ctggattggg catgatgata atcattcatt gtcacgtaga
    19201 gcaggttatt ctaataactc taattacatg gctcatctgg taaatgcgat tcagcaagct
    19261 tccccaagca tttgggggaa cgagcgcttt gctttagatc ctagtgtagt gaaatcggaa
    19321 gtcttgaaat caacaggtca aaaaccaggg aaggtttctg ttgaaggaaa agaagtagag
    19381 gtcacaggtt cgactgttac cagctattgg gctaataagg caggagcgac agcgacaagt
    19441 tatcgctttg ctattggtgg aagtgatgcg gattatcaga atgcttggtc tagtattgtg
    19501 gggagtctac caactccatc cagctccagc agttcaagta gtagttctag cgatagcagt
    19561 aactcaagta ctacacgacc ttcttcttca agggcgagac gataattctc taaatgaagt
    19621 ggccaatcaa tggattgcca cttttttctt ttcgtgttac aataagggta tgaatcagta
    19681 tcagaaaaag attgttaacg gaaaaattta ttcgctccta tccggcttaa tatggggaat
    19741 ctgtggaatt ttaggagagt acttctttac tcattatcag gtgtcttcgg gctggattac
    19801 ctctatgcgt ttgacactgg cagggagtct tgtactcatt tggtctgcaa tacaattaaa
    19861 atcgcaagtg ctagatattt ggcgagacaa gaaaaattac ctgccctttt tagcctatgc
    19921 tattttgggg attttttcag ttcagtattt tttctatctc tgtgtagaat actcaaatgc
    19981 tacgacagca actattttac agtttattag ccctgtcttt atcctctttt acaatcgctt
    20041 ggtttatcaa aaacgagcgt caaaaagcgc tgttttctat gttttggttg ccatgctggg
    20101 tgtttgcttg atggcgacaa agggagacct ctctcagtta tccatgacgc cgctagctct
    20161 tataacaggt ttgctgagtg ccatgggtgt tatgtttaat gttatcttgc cccaaccttt
    20221 tgctaagcgt tatggttttg ttcctacggt tgggtggggg atgattttgg caggtttgtt
    20281 tagcaatgtc ctctcgccgg tttatcagct ttcctttact cttgatattt ggagtatctt
    20341 gatttgcctc attatcgctt tctttggaac ggcttttgct tttttcattt ccatgaaggc
    20401 tgtgtccttg gtttctcctt tggtggtttc cgttatcagt gccagtgaac ctctctcttc
    20461 tgctctcttg agtgttttgt tcttaggatt agtagtggat tggtccctcc ttctagctat
    20521 agccttgatt attttaccca tgatattttt gtctatagaa gaagcgaaag aaagtagata
    20581 aaaagtcttt tcttaattct aaaagtgtgc tatactagaa tagtcaataa aacacgggga
    20641 gatagttgtg aagagtgttt ttaggttgta tcggtagggg cttgctttta ccgacagcac
    20701 gttttatctc acatccctaa aaaatcatac ctaaaaacag acaaaaaggt ttcaaatttg
    20761 aggccttttt tggtagaata ggtatcatta taacgaacca ggaggcacct atgactgcta
    20821 caaaaatgaa cgctcaagaa attatccaat ttatcgccaa tgctgaaaag aaaaccagtg
    20881 tcaaagtaac ctttgagggg caactcgcaa ctgctgtgcc tagctctgtt gtcaaactag
    20941 gaaatgtcct attcggagac tggaaggacg tggctccgct tcttgaaggt ttggtagaaa
    21001 atcaagatta tgttgtcgag caagatgctc gtaattctgc agttcctttg ctagataagc
    21061 gtgctatcaa cgctcgtatc gagccaggtg ctattatccg tgaccaggtg gaaattggtg
    21121 acaatgctgt tatcatgatg ggagctgtta tcaatatcgg tgctgaaatc ggtgctggaa
    21181 ccatgattga catgggtgcc atccttggtg gccgtgccat cgttggaaaa aatagccacg
    21241 ttggtgcagg tgcagttttg gcaggtgtga ttgagccagc tagtgctgaa ccagtccgtg
    21301 tcggagacaa tgttcttatc ggagctaatg cagtggttat cgaaggagtc caaatcggta
    21361 gtggttcagt tgtcgctgca ggagctatcg ttacccaaga tgtctcagaa aacgtggtag
    21421 tagcaggtgt tccagctcgt atcatcaaag aaattgatgc ccaaacccaa caaaaaacag
    21481 cgctagagga tgcgcttcgt accttgtaat tgtaaaagta aaaaagaggc ggaacccttt
    21541 ttccggcctc tttctgctat atcggaggac agatagatgt tagatttgat tcagactaga
    21601 cgagctttac accagattcc agagattggc ttggaggagt tcaagactca ggcttatttg
    21661 ctggatgtga ttgagaaatt gactacgggc aaggattttg ttcaaattcg tacttggcgg
    21721 acagggattt tggtctacct gcagggaagt cagccggagc gaaccattgg ttggcggaca
    21781 gatattgatg gcctgcctat cgtcgaacaa acaggtctac cttttgcttc tcaacaccaa
    21841 ggtcgcatgc atgcctgtgg ccatgatttt catatgacca ttgccttagg ctgtcttgag
    21901 cgcgcccttg aggagcaacc caagaataat ctgctctttc tatttcagcc tgctgaagaa
    21961 aatgaagctg gtggtatgct catgtatgag gacggtgctt ttggagattg gttgccaaac
    22021 caattctatg gtctccatgt tcgtccagat ttgaaagtcg gccagattgc gactaatact
    22081 catacactct ttgcaggaac ttgcgaggtg aagatccatt tcaaaggcaa agatggccac
    22141 gcagcttttc ctcatgaagc caatgacgcc ttggtggcgg ctagttactt tgtgacccaa
    22201 gtgcagtcag ttgttagccg caatgtcaac ccaatcgagg gagcagtggt gaccttcggc
    22261 atttttcaag ctggaaccac caacaatgtc atcacagaca cagctttttt acatggaact
    22321 attcgtgcct tgacacagga catgagtctt ttggtgcaaa agagggtaaa aacagttgca
    22381 gaaggggttg cagctgcctt tgatatggaa gtcgaagtgg aactcaaaca aggtggatac
    22441 ctacctgttg agaacaatcc agccttggcg cgtgaactga tggacttctt tgacgaaaaa
    22501 gacggaatcg agttgattga tatcgaacct gctatgacag gcgaggactt tggttatctc
    22561 ctttcaaagg ttgatggcgt gatgttttgg ctaggtatcg atagtcccta cgctcttcat
    22621 cactctcaaa tgagtcctaa ggaagaagtc ttagctattg gggtggctgc ggtgtctagt
    22681 ttcctgaaaa agaaggcagc agaatagagg gcttgtctat gaaatcggaa ttacgcaagc
    22741 aagtcttgca tgaaatgaag gctttatctc aagaacaaaa acaggctata gaccaagctt
    22801 taaccgagcg aattttacaa cacccctttt atcaagaagc caaggtcatc gcaacctacc
    22861 tctctttttc tcatgagttt caaacgcggg aactgattga gcaggcgctg aaggacggca
    22921 agaaggtttt aatacccaaa acttatccca aggggcgcat ggactttgta gtctatgatc
    22981 cgcagcagtt ggtaaaaact gcctttgcct tactggagcc acagggagat ttggaagtgg
    23041 tggatgcatc tcagattgat ttgattcatg ttcctggcct ggcttttacg acggatggat
    23101 atcggattgg atatggtgga ggttattatg accgctatct ggaacatttt tctggtcata
    23161 ctttgagtac ggttcatcct tgtcaaattc aggactttat acctgaaaac catgatattc
    23221 ctgttcagga ggtattaatt gatgaaggaa atctttgata gacgttaccc tgtgacgagt
    23281 ttcttcctct tagtgacggc cttggtattt ttactaatgt tggtcactgc aggcggaaac
    23341 tttgacaggg cagatacatt atttcgattt ggagccatgt atgggccagc tattcgcctc
    23401 tttcccgagc aggtttggcg tctcttgtct gccatttttg ttcatattgg gtgggaacat
    23461 ttcattgtta atatgctttc actttattat cttggaaggc aggtagagga gattttcggt
    23521 tctaagcagt ttttctttct ctatctttta tcaggaatga tgggcaatct ctttgttttt
    23581 gtatttagtc ctaaatcctt agcagcaggc gcctctacct ctctttatgg gctatttgcc
    23641 gcgattattg ttcttcgcta tgcaactcgc aatccttata tccaacagct agggcaatcc
    23701 tatctgacac tttttgtggt taacattatt ggaagtgttc tgattccagg aatcagccta
    23761 gcaggccata tcggtggtgc agttggtggc gcatttctag cagttatctt tccagttaga
    23821 ggagaaaaac ggatgtataa caccagccag agattaggag cggtagtctt gttcgtagga
    23881 ctcgccattt tgcttttcta caagggaatg ggaatgtgac gaagttgaaa gaaaatttgt
    23941 gtaatgaaaa aagataaggc attttttgaa ccttatcttt ttattttatt ttattccttc
    24001 tcagtcaatt cttttccaag ttggatgagg taattcttca aatcatcttt gacttgtggg
    24061 tgtttgaggg cgtagtcgat ggatgttttc atgaagccaa acttgtctcc gacatcgtaa
    24121 cgagccccat tgaactcacg agcaaataca cgttgtgttt tattgagggt gtcgattgca
    24181 tctgtcagct gaatttcatt tcctgcacct ggagcttggt tttcgaggat ttggaaaatt
    24241 tcaggcgtga ggaggtagcg tccgataata gcaaggtcgc taggagcgtc ctctggagct
    24301 ggtttttcaa caaaggtttc aacactgtaa agaccatctt ttccttcgcc ttgcggagca
    24361 ataaccccgt aagcagatac ttcgtcatga gggactggca tgacagcgat agtagacgcg
    24421 tgggtacgct cgtagtcatc catgagttgt ttggtaagtg gaacagcctt ttcgtctgtg
    24481 atatccatca agtcatcacc aagcataacg acaaaaggtt catttccgac gaaagccttg
    24541 gcttgcaaaa cagcatctcc gagaccgcgt ggatgagttt ggcggataaa atgcagccgc
    24601 atgtcagttg ttttatcaac tagcttcaaa agatctgttt tccctttttc tttgaggtta
    24661 tattccaatt cgaagtttga atcgaagtgg tcctcaatag aacgttttga tttaccagtg
    24721 acaactagaa tatcttcaat acctgatttg agagcctctt ccacgataaa ctggatagtt
    24781 ggtttgtcta cgattggcaa catttctttg gcaagggcct tggttgctgg taaaaatcga
    24841 gttcctagtc cagcagcagg gataactgcc tttctaactt ttgatgtcat aaaaatcctt
    24901 tctatagagg gttaagacca ctcattttct gctttaaatt cattgttcat gatgtcataa
    24961 atggcatctt tgatattggt tccgtgataa ataacttggt aaatagcctg tgtaatgggc
    25021 atatagactc caagttcttg ggctagttca taggctgctc gagtcgttga aattccttcg
    25081 attaccatgc ccatattagc ttctatatca gctagggatt ctcctcgtcc gagagcatct
    25141 ccagctctcc agttacgaga gtggatggaa gttcccgtta cgatcaaatc tcccacacca
    25201 gataagccgc tataggtcaa tggactggcc ccgagtgcta cccctaggcg ggtgatttct
    25261 gctaaacctc gagcgatgat ggctgcctta gcattatcac caaatccaag accatgtaaa
    25321 gctccagcac cgacagcaat aatattttta agagcaccag cagtttcaac cccgataaca
    25381 tccgtattgg tataaagtcg gaagtagtga ttactaaata gctcctgaac gtattgagct
    25441 gtttgtaaat ctttagaagc agcagttatt aaagttaggt cacgcacaat ggtctcttct
    25501 gcatgactag gccctgaaac aacgacgata tcactacgga gatgttcagg aatttcttct
    25561 tcaagaatgg ttgataatcg tttatggcta tcaggttcta atccctttga tgcgtgcatg
    25621 atgataacct tatggtccaa ggtttgtgca acttgctggg caacaagtcg tgtcactttt
    25681 gttgggacaa caaacaaaat cgcatccaca tttttcaatg tttctgctaa gtcggtgtag
    25741 gcaatgatat tttcgtctag aacgacatct ttaaagtagt gcttattagt atggtgtgta
    25801 ttaatttcat tgatttgctc gggaagattt ccccaaatac gtacctcgtg tccattgtca
    25861 tttaagactt gtgaaagggc ggttccccaa gaaccaggcc ccaagacggc gacggtttgt
    25921 ttttccatga tttcctcctt gatagatttc tttctcttat tctatcatat tctaggggat
    25981 tttgcacttg cattactggg gtatggtgga aaaatacaca aagaccgaga tgaagggata
    26041 aactcttagt ctttagttaa agtgagaaga aatctgatag atagtttgat tcagtatatg
    26101 cttataatag aggtaaacaa ctcaggaagt tcttgtaggt tgcgagagtt tggcgaaaaa
    26161 attaaaagat tacgtttggc taaaaaaatc agtcgttcag aattttgtgg tgatgagtct
    26221 gaattaagta tccgtcaatt aattagaatt gaaaatggag aatccagacc aacactaaca
    26281 aagttaaaat atattgctga acgtttggag gttgaagatt acaagttgat gccaagttat
    26341 atagagttgg ataaggaata cctagaattg aagtatttct tgatgaggac tcctacatac
    26401 gaagatgaaa ctatcgccca aaagaaagag agtgtttttg ataagatttt tgaagagtat
    26461 tatgataggc tacctgagga agaaagattt atcatcccaa attattcata tctagcacta
    26521 gcgaactaca cagttcaaaa attaccagaa aagctagttg aaatactgtc cttctggtga
    26581 ttttgcttaa tttctgatgt tcgagacatg attgaggaga tttgtcttga ttttttccta
    26641 aaaaagggca gactcctccc ttggtttgat gctcgatttt taaaataagg tgacttattc
    26701 tgttaggcag ttttcccctg ccctctagct ctatatggaa cagggagtat cagatttatc
    26761 tggcagattg tatcaaataa ggcttgaaac tgttttgaat aggcgtatag acttgagaat
    26821 ttgagaatat gtcgtctagc agtagagaca tattttccgg caatatgaag gaagagacgt
    26881 cgaaaacgct tgatagtcaa ggcctttact tcatcaccag ctagctgctt taaaaagagg
    26941 tagagattat aagccagaca gcccatcatc atacgtactt cattcttaat catggtcgaa
    27001 ctatctgtct tatccccaaa gaatcctgct ttcctttctt tgataaagtt ttcagcattc
    27061 cctcgttcac gatagaattg aaacagctcc tcactatcta cactgcttaa attggtcaaa
    27121 tgaacttttt tacaaccata aaaaagagca cttaatcgta ctcttctctt ttaaggatta
    27181 gttgaattaa ttcaaatcca ctagttctcc tgtttctagg tagactaggc gttcacaaat
    27241 gttagcaatg taatcagcga agcgttccag atgccctatg atataaaggt attgagttcc
    27301 attgggaatt gaggtttctt ggtctttcat aagtccaatg atttcctttg ataaggcata
    27361 ataatattgg tcaatctgtt catctttttg agcaatacta atagcttttg aggcttggtg
    27421 caaaggaaag gcaaccaata aatcggctag catgctgagg gataatttac ccatttggtg
    27481 taactgttct tcgtcagggg ctagttgatt ttcttttagt tgcaaaacag ctttggcaat
    27541 gcctgccata tggtctccca tacgttcaag gtctgaacaa gaagacatga tgctaatcac
    27601 aaatcgaagg tcagacactt gtggctgctg caaggccaac aaacgggcac aggtcaattc
    27661 gatagcgctt tgaccttggt ttatagcatg atccttattg ataattagct ctgccatctc
    27721 cttgtctttg gaggctaagg ccagtaaggc ttttgaagct gtttcaagga caagttgccc
    27781 tagtcctaaa aaggattgtt ctaattcatg caattctaag tcaaattgat ttctcatagg
    27841 tttttccttc cttatccgaa ccgtcctgaa atatagtctt ctgtgcgctg atcttttgga
    27901 ttggtaaaca cgtcaacggt atctccaaat tcgcaaattt ctcctgttaa gaaaaaagca
    27961 gttttatctg aaatacgtga agcttgttgc atgttatggg taacaatgat aatcgtataa
    28021 tcctttttta gttgctgaat gaggtcttca atttttaaag tggagatagg gtctaaggct
    28081 gaagtcggct catccattaa cagaatatca ggttctactg ctaaagctcg cgcaatgcaa
    28141 aggcgttgct gctgaccgcc agataaggac atggcactct ttttaagatc atctttgact
    28201 tcttcccaaa tggctgcccc ttttaaagat ttctccacta aggcatctaa ttgttttttg
    28261 tctcgaatac catgtgtcct tgggccataa gccacgttat catagataga catggcaaag
    28321 ggattaggct gttgaaaaac catccctaca cgcttacgta gctgattaag gttgaatttg
    28381 ctactataaa tatcttgctc atctaagagg acttggcctt caatatggca agaaggaacc
    28441 aaatcgttca tccggttaag ggtttttaga aaagttgatt tgccacaacc agatgggcct
    28501 atcaaggcag taatctgtct ttctggtaat tgaatcgaaa tattttttaa ggcttgaaaa
    28561 tccccgtaaa ataagtctag gtgtctgact gaaaatgttc ccatactagg aagctccttt
    28621 cacaagtttt cgagataata agcttgatag agtatttatc attaaaacag taataatcaa
    28681 aatcacaccg gtagcatagg cttcattgac atgtagcccc tcacttgaca gcatatacat
    28741 atgcagggct agagaacgac ctgaagacat gagactactt ggcgtattgg tagaggtacc
    28801 taatgtatac atgagggcag ctgtctcacc aacgatacgg ccaatagcta gtatcactcc
    28861 agctaaaata cctggcatgg caactggtag aacaattcta aaaacagtcc gtaacttacc
    28921 tgccccaagt ccataacttg cttgacgcat gctatcacta acagataaaa gggcttcttc
    28981 tgttgagcga ataatgactg gcaacaccat gatgactgag gttaagattc ctgataacag
    29041 agagtattga aaacctaaga agactacaaa gaagagcatg ccaaacagac caaaaacaat
    29101 ggaaggaatc ccagacaagg tatctgaggc caatcgcatg attttaacac aaagggaatc
    29161 tttttttgta tattccacaa gataaaaacc agcaaaaatc cctatgggca aggctaaaag
    29221 aagagcacca aagaccagaa taacggtgga aataatcgct ggcataaggg aaatgttctc
    29281 agaagtataa gtccaagaaa agagggatag acttagatga ggtaaacctt tgatgaggat
    29341 aaaaccaatg attaaaaaga gagagccaaa ggttaaagct gaaaaacaat aaacgagaag
    29401 ttttagcagg tatttactca taagatgatt ttcctttcaa gtaggcaaag taggcattaa
    29461 tcaagagaat aaggaaaaag agaactgctg aggttgcaat aagggcttcc ctatgctgac
    29521 ctgatgcgta agccatttcc agaacaatat tggttgttaa ggttctggtt cctgaaaaga
    29581 gtccacttgg aataatcggc tggttgcctg ccaccaaaat aactgccatg gtttcaccta
    29641 ctgcgcgacc gatgcctaaa ataactgctg ataaaatacc agatctcgca gctggcaaga
    29701 tgacactaaa aatactccgt tcatgactag ctcctagagc caagctacca gaataatacg
    29761 ttttgggaac tgttcggata gcagattctg acaaactgat aatggttggc aaaatcatta
    29821 ttcctaatag taacgaagcg gttaggacac tcatgccatt tcctaaaaag cttctaatcc
    29881 aaggcaccaa taattgtagg ccgaaaaaac cataaacaat agatggaatg gccgccatca
    29941 agttgatagc tgattttaag aagccataga cgggctttgg acaataataa accataaaca
    30001 ccgatgtcaa gatgcctgtt ggcaccccaa tcacaatcgc tcctaaggta attaataagg
    30061 aaccaacgat cattggtaaa ataccatagc ttgccggaat gttcgttggc gaccaatcac
    30121 tgcctaataa aaaacgggca aagccgtagt tagccatgaa aggtaagcca ttactaaaaa
    30181 taaagaaaca gattagcaaa atagctacaa cagctactgt tgcactcatg aaaaaaattg
    30241 ccctaaaaac tgcttctttg aaggcttgtt ttatcacatc ttgtcctttc tagtgaagaa
    30301 agtaagggag atacgacacc tccctacttg ccttctttat cttattgtac gatgaaacgt
    30361 ctgcatctct ttagagattt atggagcaaa cattttattt aatcttgtcc caggtggtta
    30421 atttgccact aaaaacgtct gcaagttcag ccatactgac ttggcttgcc ttattgtcat
    30481 tattgaccac aacagcaata ccgtctaaag caatagcatc atgggtgaga ctcttacctt
    30541 cttcaggagt taattcccta gaaaccatac caatatcagc ggttttctcc ttaacagcgg
    30601 taatacctgc tgaagaccca ttagaggtaa tatcaatcgt aacttctgga ttttcttttt
    30661 tataagcttc tgctaatttt tccattaaag aagatactga agtggaacct acaacagaca
    30721 acttgcctga taagtgttgg cttgtatatt ctgtggtttc agttttagct tcaataaatt
    30781 tattatctgt gaccacttgt tgaccttgtt tggagtggat aaagctgata aaatcttgac
    30841 ctagcttgga aagattagaa gaccaaacaa tgttgaaggg acgttgaaga gggtattcac
    30901 catctaaaac tgtgtctcga ctagccttga caccatcaat ctctaaagcc ttgacagatt
    30961 tcgttaaaga tcccaaggag atgtagccga tagcattagc attcccttga actgctgaga
    31021 gaacaccttc tgtactattt tgaatcacag ctgttttggc agtgttgtca atttttttat
    31081 caccgtcttt tttgagaatc cctgtgattt ctgtgaaggc accccgtgtt ccagagccat
    31141 tttctcgtga aatcacctca atcgttcctg aagctgactg tttggaagca gctgactgat
    31201 tgccacaggc aacaagccca aatcctgata agccaatggc tgcaagagta agcatttttt
    31261 tgaatttcat aataatcacc tttatctcta tgtatttttc ttgtgtaggc ttactacatt
    31321 tatagtctaa caagtctttg taaaggttta tccctgattc atgtaaagat tgtgtaaaga
    31381 atcaaaaaaa gccacttttg aaaaatggct gctcctaaaa atagctttaa aaattattag
    31441 tcctgtgcga aagattggtt aggaagaaaa atcgtgaagc aactgcctct gccaagctga
    31501 ctcgtcaccg tgacttggcc acctaataat tgactgagtt ctttgacaat ggcaaggcca
    31561 agaccagtgc caccagtttg tctgcttcga cctttattaa ctcggtaaaa acgttcaaaa
    31621 atacgatcct gctctaattg actaatacca atccctgtat ctgatacaga aatcttaatg
    31681 ccttcgttca ccttttgggt cttgacctca atttttcccc cttgttcagt gtaacggatg
    31741 gcattggata aaagattgag taagatttgg gaaagtaatt gactatctga tacgagggtg
    31801 acatcatctg gcacctgcac ctttagctgt aaatccttct tcttgagctg aggttgcaag
    31861 ctttgagtca aatcctgtac aaattcagcc aaagaaaggg tcgtccattg tataggcatt
    31921 tgttgagcct tagataaggt aagaagatgc tcaacaatat gctcaagacg caaactttct
    31981 ttgtaaataa tgtctagaaa gtcatccttg agcgcttctt cttcagctga catcccctta
    32041 atggtttcag caaagccctt aattgaagta actggtgtcc tcaattcatg ggaggcattt
    32101 gagacaaagg ctaaatttaa cttttcataa gttctaatcg ttgttaaatc atatagcaag
    32161 acgagcacag cttccacaga ttgggtgggg ctaaaaacgg gaactgctgt cacttctaaa
    32221 atcaagtcac cctcatgaaa cccacttact tcttgtttta accttgtttt ttgatcaaag
    32281 gcttggtgaa ctaaattccg aatatccatc cgtttgaggt catcaagtga acttatgtcg
    32341 ccgtccacat cgggaaaata atgaggcaga gagcgactgg ataataacat ctgaccttga
    32401 gcggaaacta aaaacgtccc catggttagg tgcgacagaa gaacctccat tgtttcggct
    32461 aggtccttgt attgctgatc ctgttgggag actttggttt ttaggccaga cacatactga
    32521 gccaaagact ttaagtcttc ttgccctttt tctaaaaagt attcactact ggtcaagaga
    32581 ggttggtgca aggtctcaaa agcaacttcc catttccaaa ggcaaaagag ccagtagcca
    32641 ccttgtccca aagaaagggc tagaagaaag agaccgatgc ctttactgat ccaagttaat
    32701 gccatccctg caatcagaat gaggctaaca cttagattga ctagccaaaa ttgaaggtag
    32761 cgtttcatct ataactcctt gaacttataa ccataacccc gaatggttcg aataaattga
    32821 ggggctttag gattgtcttc aattttttcc ctcaacttac caatatgaac gtccaccaaa
    32881 cgtgtttcct gcccaaagtc atacccccag atacgttcca aaagacgctc tctagtcagt
    32941 gtcatgttgg gatgtttcat aagatagagc aagagttcaa attcttttgg ggtcaaactc
    33001 agtaacttat tcgccttgta gacttcatga cgctcagggt atactttcaa ggtcccaaat
    33061 agccaagaat cgtcagcgat attatctgaa tcatctcctt cttgttctcc tttagttcgc
    33121 ctgaggacag ccttgacacg cgccagcaat tctctagggc taaaaggctt ggtcaggtag
    33181 tcatcagccc ctaattccaa ggccaaaacc ttatcaaatt catcactttt cgcagaaacc
    33241 atcataattg gagttttgac gcctttggct ctcagccgct tacaaacttc catgccatct
    33301 aattgtggta acatgatatc aagcaagata aaatcaaagg gttctgtttc tgccaaagct
    33361 aaggccttcc gtccatttgt taccaattga gtagaaaagc cttccttact taaatggtag
    33421 tcaagcaatt tcagaatgtg ttcttcatca tccactaata agacttgttt tgtcatctat
    33481 tatctcctat tggtaacatt ataacacaat tatcagaaat cctaacattg ctaaatcaga
    33541 ttaaatttgc ttatcaagac tagtatctgg tcaaacgctc aatcatctcc ttgtgctctg
    33601 gataggtcgc cagtagatct accctttcaa ataattcaaa atcctcaaat tcaaaaccag
    33661 gagcaacaag acaagaaacc agagcataat ccttatcaac tgttgatccc caaatagtgc
    33721 ccttaggaac acagtagtga agttgttgcc ctttggatat gtccaggcct aaagtgactg
    33781 cttcgtagtg accatctgct gtaatcatgt gaacagtaag tggggatcct gcatgaaaat
    33841 accagatttc atctgctgtc aatcggtgaa aatgtgaagg attcgtttct tctaataaga
    33901 aataaatact ggtataaagc gcccttccct taccagcaag gtttatagtg tctgaagctt
    33961 tttttgtttg tctaaaatag ccaccttcaa catggggagc taactctaga gttcttatca
    34021 agtcttcttt atccatcggg gccaatgggt tgaagtaact cttgttcaaa gtggttttac
    34081 gatttcaaga actcctctca gttctgagga cacggtaatg attgatgcga cggaagtaca
    34141 aatcaatcgc cctaaaaaaa gaattagcga atgattctgg taaaaagaaa tttcacgcta
    34201 tgaaggctca agcgattgtc acaagtcaag ggagaattgt ttctattgcc atgatatgaa
    34261 gttgttcaaa atgagttgca gaaatatcgg acaagctggt aaaatcttgg ctgacagtga
    34321 ttatcaaggg ctcatgaaga tatatcctca agcacaaact ccacgtaaat ccagcaaact
    34381 caagccgcta acagctgaag ataaagccta taaccatgcg ctatctaagg aaagaagcaa
    34441 ggttgagaac atctttgcca aagtaaaaac gtttaaaata ttttcaacaa cctatcgaaa
    34501 tcatcgtaaa cgcttcggat tacgaatgaa tttgattgct ggtattatca atcatgaact
    34561 aggattctag ttttgcagga agtctattat ttggttaggt gaattagtga agtgtttagg
    34621 caagtgtctc tggttacgac gtcatggcct ctaaatcgat tatatttagg ggtcatgact
    34681 agtgaagcgc ctagccaaag tccgaatagg atttggcgtt agttacttag attgctttgc
    34741 aatcaagtaa ctttggcgat ttacatcttc tctggcgctt ctactccaag caagcgaagg
    34801 gcttctttga gaacgactgc ggttgcgtag ctgagggcta gacggctgtc gcgttctggg
    34861 ctttcatcca agatacgtgt atgtgcatag tatttgttaa aggattgagc caggctaatt
    34921 gcaaatttag caatgataga aggttcaaag ttatctgccg cacggttgat aatacgtggg
    34981 aagtcttgaa tgagtttaat gatttcccag ctttcagtat cattcaagct atagttgcca
    35041 gctgtttctg gtttgaaatc ggctttgcgt aagatagatt ggatacgagc gtaggcatat
    35101 tgaacgtaag gtccagtttc accctcgaag gataccatag cttctaggtc gaagtcgtat
    35161 ccatttgtac ggtcagtttt gaggtcatag aatttaatgg ctccaacccc aacagcatgt
    35221 gctacttggt ctttgttttc tagttcagga tttttagcct cgatttggac cttggcacgg
    35281 ctaacagcct ctgcaacagt aggctctagc aagatgacat tccctttacg agtagagagc
    35341 ttcttccctt cttttgtaac cagaccaaaa ggaacgtggg taatgtcgtc actccaatcg
    35401 tagcccatct cttgcaagac agctttgagt tgtttaaagt gggcagattg ctcttgacca
    35461 acgacgtaga tagatttagc aaattggtat tcatttttac ggtagagggc tgcagccaag
    35521 tcacgtgtga tatagagagt tgcaccatca gacttcttga tgagggctgg atgttcaatt
    35581 ccatatttct caagattcac aacttgggca ccttctgatt caagaagtag tcctttttca
    35641 gaaagaatgt ctacaactgc atccatctta tcattgtaga aggcttctcc gttatagctg
    35701 tcaaattcaa ccttcaattc attgtaaagg cggttaaatt ccactaaact ttcatcgcgg
    35761 aaccattgcc aaagagcgag agcttcctca tctccatttt caagtttacg gaaccattcg
    35821 cgcgcttctt catccaagct agggtcattt tcagcttcag cgttgatgcg gacatagagt
    35881 ttaaggagtt catcgattgg atgagctttt acagcttctt cgtcgcccca ttttttgtag
    35941 gcaacaatca acatcccaaa ttgtttaccc cagtctccca aatggttgac cttgaccgtt
    36001 tgataaccga ttttttggaa aatatgtgac aagctatctc cgataacagt tgaacgcagg
    36061 tggccaatag aaaatggttt agcgatattc ggactagaca tgtcgataac aacattttct
    36121 tgtttgccaa tattttggtc agcatagtgt tctttttcag tggtaacagc ttgcaatact
    36181 tgagcagaaa tggcagattt atcaaggaaa aagttaacgt aaggtcctgt tgcgacaact
    36241 ttttcaaagg cttggctgtt cattttttca gccagttcag ccgcaatcat ttgtggtgct
    36301 ttacgttcga ctttggcaag agaaaaagca gggaaagcaa tgtctcccat ttctgagttt
    36361 ttaggggttt ccagtaactt taaaatagcc tcttggtcca ggctatcaat gatgctagat
    36421 aattcgctag caatcaattc ttttgtattc attaagagct cctttttgga cttttctact
    36481 attttatcac aattttaaag aaagaagaaa aaatttttga aatctcctgt ttttttggta
    36541 taatatggtt ataaatatag ttataaatat gcacgcaaga ggattttatg agaaaaagag
    36601 atcgtcatca gttaataaaa aaaatgatta ctgaggagaa attaagtaca caaaaagaaa
    36661 ttcaagatcg gttggaggcg cacaatgttt gtgtgacgca gacaaccttg tctcgtgatt
    36721 tgcgcgaaat cggcttgacc aaggtcaaga aaaatgatat ggtgtattat gtactagtaa
    36781 atgagacaga aaagattgat ttggtggaat ttttgtctca tcatttagaa ggtgttgcaa
    36841 gagcagagtt taccttggtg cttcatacca aattgggaga agcctctgtt ttggcaaata
    36901 ttgtagatgt aaacaaggat gaatggattt taggaacagt tgctggtgcc aataccttat
    36961 tggttatttg tcgagatcag cacgttgcca aactcatgga agatcgtttg ctagatttga
    37021 tgaaagataa gtaaggtctt gggagttgct ctcaagactt atttttgaaa aggagagaca
    37081 gaaaatggcg atagaaaagc tatcacccgg catgcaacag tatgtggata ttaaaaagca
    37141 atatccagat gcttttttgc tctttcggat gggtgatttt tatgaattat tttatgagga
    37201 tgcggtcaat gctgcgcaga ttctggaaat ttccttaacg agtcgcaaca agaatgccga
    37261 caatccgatc cctatggcgg gtgttcccta tcattctgcc caacagtata tcgatgtctt
    37321 gattgagcag ggttataagg tggctatcgc agagcagatg gaagatccta aacaagcagt
    37381 tggggttgtt aaacgagagg ttgttcaggt cattacgcca gggacagtgg tcgatagcag
    37441 taagccggac agtcagaata attttttggt ttccatagac cgcgaaggca atcaatttgg
    37501 cctagcttat atggatttgg tgacgggtga cttttatgtg acaggtcttt tggatttcac
    37561 gctggtttgt ggggaaatcc gtaacctcaa ggctcgagaa gtggtgttgg gttatgactt
    37621 gtctgaggaa gaagaacaaa tcctcagccg ccagatgaat ctggtactct cttatgaaaa
    37681 agaaagcttt gaagaccttc atttattgga tttgcgattg gcaacggtgg agcaaacggc
    37741 atctagtaag ctgctccagt atgttcatcg gactcagatg agggaattga accacctcaa
    37801 acctgttatc cgctacgaaa ttaaggattt cttgcagatg gattatgcga ccaaggctag
    37861 tctggatttg gttgagaatg ctcgctcagg taagaaacaa ggcagtcttt tctggctttt
    37921 ggatgaaacc aaaacggcta tggggatgcg tctcttgcgt tcttggattc atcgcccctt
    37981 gattgataag gaacgaatcg tccaacgtca agaagtagtg caggtctttc tcgaccattt
    38041 ctttgagcgt agtgacttga cagacagtct caagggtgtt tatgacattg agcgcttggc
    38101 tagtcgtgtt tcttttggta aaaccaatcc aaaggatctc ttgcagttgg cgactacctt
    38161 gtctagtgtg ccacggattc gtgcgatttt agaagggatg gagcaaccta ctctagccta
    38221 tctcatcgca caactggatg caatccctga gttggagagt ttgattagcg cagcgattgc
    38281 tcctgaagct cctcatgtga ttacagatgg gggaattatc cggactggat ttgatgagac
    38341 tttagacaag tatcgttgcg ttctcagaga agggactagc tggattgctg agattgaggc
    38401 taaggagcga gaaaactctg gtatcagcac gctcaagatt gactacaata aaaaggatgg
    38461 ctactatttt catgtgacca attcgcaact gggaaatgtg ccagcccact ttttccgcaa
    38521 ggcgacgctg aaaaactcag aacgctttgg aaccgaagaa ttagcccgta tcgagggaga
    38581 tatgcttgag gcgcgtgaga agtcagccaa cctcgaatac gaaatattta tgcgcattcg
    38641 tgaagaggtc ggcaagtaca tccagcgttt acaagctcta gcccaaggaa ttgcgacggt
    38701 tgatgtctta cagagtctgg cggttgtggc tgaaacccag catttgattc gacctgagtt
    38761 tggtgacgat tcacaaattg atatccggaa agggcgccat gctgtcgttg aaaaggttat
    38821 gggggctcag acctatattc caaatacgat tcagatggca gaagatacca gtattcaact
    38881 ggttacaggg ccaaacatga gtgggaagtc tacctatatg cgtcagttag ccatgacggc
    38941 ggttatggcc cagctgggtt cctatgttcc tgctgaaagc gcccatttac cgatttttga
    39001 tgcgattttt acccgtatcg gagcagcaga tgacttggtt tcgggtcagt caacctttat
    39061 ggtggagatg atggaggcca ataatgccat ttcgcatgcg accaagaact ctctcattct
    39121 ctttgatgaa ttgggacgtg gaactgcaac ttatgacggg atggctcttg ctcagtccat
    39181 catcgaatat atccatgagc acatcggagc taagaccctc tttgcgaccc actaccatga
    39241 gttgactagt ctggagtcta gtttacaaca cttggtcaat gtccacgtgg caactttgga
    39301 gcaggatggg caggtcacct tccttcacaa gattgaaccg ggaccagctg ataaatccta
    39361 cggtatccat gttgccaaga ttgctggctt gccagcagac cttttagcaa gggcggataa
    39421 gattttgact cagctagaga atcaaggaac agagagtcct cctcccatga gacaaactag
    39481 tgctgtcact gaacagattt cactctttga tagggcagaa gagcatccta tcctagcaga
    39541 attagctaaa ctggatgtgt ataatatgac acctatgcag gttatgaatg tcttagtaga
    39601 gttaaaacag aaactataaa accaagactc actagttaat ctagctgtat caaggagact
    39661 tctttgacaa ttctccactt ttttgctaga ataacatcac acaaacagaa tgaaaaggag
    39721 ctgacgcatt gtcgctccct tttgtctatt ttttaaggag aaagtatgct gattcagaaa
    39781 ataaaaacct acaagtggca ggccctggct tcgctcctga tgacaggctt gatggttgct
    39841 agttcacttc tgcaaccgcg ttatctgcag gaagtcttag gcgccctcct tgctgggaaa
    39901 tatgaagcta tttatagtat cggggcttgg ttgattggtg tggccgtagt cggtctagtt
    39961 gctggtggac tcaatgttgt cctcgcagcc tatattgccc aaggagtttc atccgacctt
    40021 cgggaggatg ccttccgtaa aattcaaacc ttttcttatg ctgatattga acaatttaat
    40081 gcgggaaatc tagtcgttcg aatgacaaat gatatcaacc agattcagaa cgttgtcatg
    40141 atgaccttcc agattctttt cagacttccc ctcttgttca tcggttcgtt tatcctagcg
    40201 gttcaaacct taccttctct gtggtgggtg attgttctca tggtagtctt gatttttggt
    40261 ttgactgctg tcatgatggg aatgatgggg cctcgttttg ccaagtttca aacccttctt
    40321 gagcgcatca atgccattgc caaggaaaat ttacgtggcg ttcgtgtggt caagtccttt
    40381 gtccaagaaa aagagcaatt tgctaagttt acagaggtct cagacgagct tcttggtcaa
    40441 aacctttaca ttggttatgc cttttcagta gtggaaccct ttatgatgtt ggttggttac
    40501 ggggcggtct tcctctctat ttggctggtc gcgggaatgg ttcagtcgga tccgtctgtt
    40561 gttggttcca tcgcttcttt tgttaattac ctaagccaga ttatctttac cattgttatg
    40621 gttggatttt tgggaaattc tgtcagccgt gccatgattt ccatgcgtcg tattcgagaa
    40681 attcttgacg cagagccagc tatgaccttc aaggatatcc cagatgaaga gttggttgga
    40741 agccttagct ttgaaaatgt gacctttacc tatccaatgg acaaggaacc gatgctgaaa
    40801 gatgtgagct ttactattga acctggtcaa atggttggtg tagttggagc gactggtgca
    40861 ggaaagtcaa ccttggctca attgattcca cgtctctttg atccacagga aggggctatc
    40921 aaaatcggag gtaaggatat tcgagaagtg agtgaaggaa ccctgcgtaa aacagtttcc
    40981 atcgttctcc aacgtgccat tctttttagt ggaacgattg cagataactt gagacagggg
    41041 aagggaaatg ctactctatt tgaaatggag cgcgcagcca atattgccca ggctagtgaa
    41101 ttcattcatc gtatggagaa aacctttgaa agtccagttg aagaacgggg aaccaatttc
    41161 tctggtggac aaaaacaaag gatgtcgatt gcgcgtggga ttgtcagcaa tccacgtatt
    41221 ctgatttttg atgattcgac ctcagccttg gatgccaaat cagagcgctt ggtgcaagaa
    41281 gctttgaata aggacttgaa ggggacgaca accattatta ttgctcaaaa aattagctcg
    41341 gttgtccatg cagacaagat cttggttcta aatcaaggac gattgattgg tcaaggcacg
    41401 catgcagact tggttgccaa caatgccgtt taccgtgaaa tctatgaaac acagaaatga
    41461 aagacaaact ataagaaaag tcaatagttt tatctaaact atttcttatt tcaatttgat
    41521 gatttggcga tgattttaga gcacggcaaa aagctattga aaaagtccat tttttcaaag
    41581 gtaatcctgt gttaatttca gaaattacat cactttttgt tcgtcaaatg gcagctcttt
    41641 tttaggatat aaaacagggt tcggataagt ttttttgcaa ggtggatgat ggctacattg
    41701 taatgttttc cttgttctaa cttagtctta agataggcct taaaagcagg tgaaaagcga
    41761 gggcatgctt tggcagcttg tatgagtacc taccgcagat gaggggaacc ccgtttgacc
    41821 attcttcctg ctaaatcaat ctgacctgac tgataaatag aagaatccag tccagcgaaa
    41881 gcttgtaatt gagcaggatt atcaaaggca tgaatatttc gaatctcggc taaaatgacc
    41941 gcccctaaac gattctcaat cccagtaacc gtcgtgatga ccgagttgaa ctcagccatc
    42001 aagtcattga cacatttttt cgccttgtca atgagcctct tgtaatgttt gatgttttca
    42061 ttacaagaga taaaacgttt atgcgttatc aaactcatta ccaattgaaa caaaaagctg
    42121 tggttagatc ctttcggaaa ttgtcaagcg attggaggaa atgaactaat ccacagcggc
    42181 ttattccaag tataccactt gggctttggc agtagctaac tgcgctaaat ataatataag
    42241 gaggagtaaa atgaagacag ttcaattttt ttggcattat tttaaggtct acaagttctc
    42301 atttgtagtt gtcatcctga tgattgttct ggcgactttt gcccaagccc tctttccagt
    42361 cttttctgga caagcggtga cgcagctagc caatttagtt caagcttatc aaaatggcaa
    42421 tccagaactt gtatggcaaa gcctatcagg aatcatggtc aatcttggcc tgctggtttt
    42481 ggttctattt atctctagtg taatatacat gtgtctcatg acgcgcgtga ttgcagaatc
    42541 gaccaacgag atgcgcaaag gcctctttgg taagcttgct cagttgacgg tttctttctt
    42601 tgaccgtcga caagatggcg atatcctgtc tcattttacc agtgatttgg ataatatcct
    42661 ccaagccttt aacgaaagct tgattcaggt catgagcaat attgttttat acattggtct
    42721 gattcttgtc atgttttcga gaaatgtgac gctggctctc atcaccattg ccagcacccc
    42781 attggctttc cttatgctga ttttcatcgt gaaaatggca cgtaaataca ccaacctcca
    42841 gcagaaagag gtagggaagc tcaacgccta tatggatgag agcatctcag gccaaaaagc
    42901 cgtgattgtg caaggaattc aagaggatat gatggcagga tttcttgaac aaaatgagcg
    42961 cgtgcgcaag gcaaccttta aaggaagaat gttctcagga attcttttcc ctgtcatgaa
    43021 tgggatgagc ctgattaata cagccatcgt catctttgct ggttcggctg tacttttgaa
    43081 tgataagtct attgaaacaa gtacagccct aggtttgatt gttatgtttg cacaattttc
    43141 acagcagtac taccagccta ttatccaagt tgcagcgagt tggggaagcc ttcagttggc
    43201 ctttactgga gctgaacgaa ttcaggaaat gtttgatgca gaggaggaaa tccgacctga
    43261 aaaggctcca accttcacta agttgcaaga aagtgttgaa atcagtcata tcgatttttc
    43321 atacttgcct gataaaccta ttttgaaaga tgtcagcatt tctgccccta aaggccagat
    43381 gacagcagtt gttgggccta caggttcagg aaaaacgact attatgaacc tcatcaatcg
    43441 cttttatgat gttgatgctg gtggtattta ttttgatggt aaagacattc gtggctatga
    43501 cttagatagt cttagaagca aggtgggaat tgtattgcaa gattcggtct tgtttagcgg
    43561 aacgattcga gacaatatcc gatttggtgt gccagatgct aatcaggaaa tggttgaggt
    43621 agcagcaaaa gcaacccaca ttcacgacta tatcgaaagt ttgcctgata agtacgatac
    43681 tcttattgat gatgaccaga gcatcttttc aacagggcag aagcaattga tttcaatcgc
    43741 tcgaaccctg atgacagatc cagaagttct cattctcgat gaagcaactt caaacgtaga
    43801 tacggtgacg gaaagcaaga ttcagcatgc catggaggtg gttgtagcag gtagaactag
    43861 tttcgtcatt gcccaccgct tgaaaaccat tctcaatgca gatcagatta ttgtccttaa
    43921 agatggagaa gtcattgaac gtggtaacca ccatgaactt ttgaagctag gtggctttta
    43981 ttcagaactc tatcacaatc aatttgtttt cgaataagaa agaagttgtc ctatgtgggc
    44041 agctttttct tgtccataaa aaatgtttat cacagcctta aaaaaaacat attagacgaa
    44101 agtcattttg agtgatatga taggactatc gttagtattc gaaaggagag gcatcatggc
    44161 tagaacggtt gtaggagttg ctgcaaatct atgtcccgta gacgcagaag gcaaaatcat
    44221 tcattcatct gtatcttgta gattcgcaga gatcattcgt caagtcggtg gtctcccttt
    44281 agtcattcct gttggtgatg agtcagttgt acgtgattat gtggaaatga ttgacaaact
    44341 cattttgaca ggaggccaaa atgttcatcc tcagttttat ggagagaaaa agaccgtcga
    44401 aagcgatgat tacaatctgg tccgtgacga atttgaattg gcactcttga aggaagcgct
    44461 tcgtcagaat aaaccaatta tggcaatctg tcgcggtgtc caacttgtca atgttgcctt
    44521 tggtggaacc ctcaatcaag aaatcgaagg tcactggcaa ggactacctt tcgggacatc
    44581 tcactctatt gagacagtag aaggaagcgt ggtggctaag ctatttggga aagaaagtca
    44641 ggtcaactca gtccatcgtc aaagcattaa agatttggca cctaatttcc gtgtaactgc
    44701 tattgattca agagaccaaa ctattgaagc gattgagtct atcgacgagc accgcattat
    44761 cggtttacag tggcatccag agtttctggt taatgaagaa gatggcaatt tagaattatt
    44821 tgagtattta ttgaatgaac tgtaacgatt ggaacatctg gtcgttcttt cttttatttt
    44881 ttcaaaattt ttagaatgtg gcattttacg caaacgtttg aattctgata aaaattggag
    44941 aaattcgaca aaaaaacttg aaaaaaacga aggtaagcgt tatgatagaa aagaagaaat
    45001 attggaggaa gaacatgtca catattaaat ttgattattc aaaagtttta gacaaatttg
    45061 ttgcaccaca tgaagtggaa tacatgcaat cacaagtaac agcagcagat gaattgatcc
    45121 gtaaaggaac tggtgctggt agcgacttct tgggatggtt ggaccttcct gaaaaatacg
    45181 accgcgaaga atttgaccgc atcttgaaag ctgctgagca aatcaagtca gacagcgatg
    45241 ttttggttgt gatcggtatt ggtggatctt accttggtgc aaaagcagca atcgacttct
    45301 tgaatcacca ttttgctaac ttgcaaacaa aagaagaacg caaagctcca caaatccttt
    45361 acgcaggaaa ctcaatctca tctacttacc ttgctgactt ggtagagtat gttgcagaca
    45421 aagacttctc agtaaacgta atttctaaat caggtacaac aactgaacca gcgattgctt
    45481 tccgtgtctt taaagaactc ttggttaaga aatacggtca agaagaagct aacaaacgta
    45541 tctatgcaac aactgaccgc caaaagggtg ctgttaaggt tgaagcagac gctaacggtt
    45601 ggggaacatt tgttgttcca gatgatatcg gtggacgctt ctcagtattg acagccgttg
    45661 gtttgcttcc aatcgcagca tcaggagctg acatcaaagc tcttatggaa ggtgcgaatg
    45721 cagctcgcaa agactacact tcagacaaaa tctctgaaaa cgaagcttac caatacgcag
    45781 tcgttcgtaa catcctttat cgtaaaggct atgcaactga gatcttggta aactatgagc
    45841 catcacttca atacttctca gaatggtgga aacaattggc tggtgaatca gaaggaaaag
    45901 accaaaaagg tatctaccca acttcagcca acttctcaac tgacttgcac tcacttggtc
    45961 aatttatcca agaaggaact cgtatcatgt ttgaaacagt tgtccgtgtt gacaaacctc
    46021 gtaaaaacgt gcttattcct actttggaag aagaccttga cggacttggt taccttcaag
    46081 gaaaagacgt tgactttgta aacaaaaaag caactgacgg tgttcttctt gcccacacag
    46141 atggtgatgt accaaacatg tatgtgactc ttccagagca agacgctttc actcttggtt
    46201 acactatcta cttcttcgaa ttggcaattg ccctttcagg ttacttgaat gctatcaacc
    46261 catttgacca accaggtgtt gaagcttata aacgtaacat gtttgccctt cttggaaaac
    46321 caggatttga agaattgagc aaagaactta acgcacgtct ataatagaag aaaagagtgg
    46381 tttgcccact ctttttactc tctttatcca tagaaattgg actcagccaa gacttgtgat
    46441 ataatataga aagcaaaaag gcagacgcct agataatagg agaaactatg tcaaaagata
    46501 tccgcgtacg ttacgcacca agtccaacag gactactaca catcggaaat gcccgtacag
    46561 cattgtttaa ctacttgtat gcgcgccatc atggtggaac atttctcatc cgtatcgaag
    46621 atactgaccg taaacgccat gtcgaggatg gtgaacgttc acaacttgaa aaccttcgct
    46681 ggttaggcat ggattgggat gaaagtccag aatcacatga gaattatcgc cagtctgagc
    46741 gtttggactt gtatcaaaaa tacattgacc aactattagc tgaaggaaaa gcctataaat
    46801 cttacgttac agaagaagag ttggcagctg aacgtgaacg tcaagaagta gctggcgaaa
    46861 caccacgcta catcaatgaa taccttggta tgagtgaaga agaaaaagcg gcttatatcg
    46921 cagaacgtga agcagctggt atcataccaa cagttcgttt ggctgtcaat gagtcaggta
    46981 tctacaagtg gcatgatatg gtcaaaggtg atatcgaatt tgaaggtggc aatatcggcg
    47041 gtgactgggt tatccaaaag aaagacggtt acccaactta caactttgcc gttgttatcg
    47101 atgaccacga tatgcaaatc tctcatgtta tccgtggaga tgaccatatt gctaatacac
    47161 caaaacagct tatggtctat gaagctcttg gttgggaagc tccagagttt ggtcacatga
    47221 ccttgattat caactctgag actggtaaga agttatctaa acgtgatact aatacacttc
    47281 aatttatcga agattaccga aagaaaggtt accttccaga agcagtcttt aactttattg
    47341 ctcttcttgg ttggaaccca ggtggtgaag atgagatttt ctctcgtgaa gaactcatta
    47401 aactttttga tgaaaaccgc ctcagcaagt caccagcagc ctttgatcag aaaaaattag
    47461 actggatgag caatgattat atcaagaatg cagaccttga aaccatcttt gaaatggcaa
    47521 aaccattctt agaggaagca ggccgtttga ctgacaaggc tgaaaaatta gttgagctct
    47581 ataaaccaca aatgaaatca gtagatgaga ttatcccatt gacagatctt ttcttctcag
    47641 atttcccaga attgacagaa gcagagcgcg aagtcatgac gggtgaaaca gttccaacag
    47701 ttcttgaagc attcaaagca aaacttgaag cgatgacaga tgatgaattt gtgacagaaa
    47761 atatcttccc acaaattaaa gcagtccaaa aagaaacagg tattaaaggg aaaaatcttt
    47821 tcatgcctat tcgtatcgca gtttcaggcg aaatgcatgg gccagaatta ccagatacaa
    47881 ttttcttgct tggacgtgaa aaatcaattc agcatatcga aaacattcta aaagaaatct
    47941 ctaaataaag aggatacaat aatggacatc tgggaaaaga tgtacgaaga agcacagaaa
    48001 ctatacaatc cacatgaagt atcagacttt gtttatgcca atcatgttgt agctgcagta
    48061 gaagcaggag atggacaaat atttacagga ttctgtatgg agggaacctg tggtgttttc
    48121 catctctgcg cagaacgggc gaccctcttc aatatgtacc aattttcagg acaaactaag
    48181 gttaagaaag tattagcctt tcgagacaaa ccaccttatg gtggaagttc agccatgcct
    48241 tgcggtgctt gtagagaatt ccttttagag cttaatgctg aaaataaaga tgcagaattc
    48301 atgatggact ataatataag aaaaacagtt aaagtcgcag aactaatccc ttattggtgg
    48361 ggagaagaac gtgcttctaa gtttaatgag tgatagaaga gtcagtataa ttctggctct
    48421 ttttactata agttgaaaaa ataaaaaaaa ttagaaaaag tagttgacaa aatttgaaaa
    48481 g
//
LOCUS       DBEJHE010000013        48258 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC4 isolate 671759
            SAMN38261586-rid24793303.denovo.13, whole genome shotgun sequence.
ACCESSION   DBEJHE010000013 DBEJHE010000000
VERSION     DBEJHE010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261586
            Sequence Read Archive: SRR26833752
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 48258)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48258)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576136.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576136.1
            Genome Coverage       :: 109x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 19:48:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,067
            CDSs (total)                      :: 2,029
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 131
            CDSs (without protein)            :: 131
            Pseudo Genes (ambiguous residues) :: 0 of 131
            Pseudo Genes (frameshifted)       :: 64 of 131
            Pseudo Genes (incomplete)         :: 59 of 131
            Pseudo Genes (internal stop)      :: 46 of 131
            Pseudo Genes (multiple problems)  :: 32 of 131
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48258
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261586-rid24793303.denovo.13"
                     /strain="GPSC4"
                     /isolate="671759"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            9..89
                     /locus_tag="ACL3EZ_001022"
     tRNA            9..89
                     /locus_tag="ACL3EZ_001022"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:43..45,aa:Tyr,seq:gta)
     gene            94..164
                     /locus_tag="ACL3EZ_001023"
     tRNA            94..164
                     /locus_tag="ACL3EZ_001023"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:126..128,aa:Trp,seq:cca)
     gene            179..251
                     /locus_tag="ACL3EZ_001024"
     tRNA            179..251
                     /locus_tag="ACL3EZ_001024"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:212..214,aa:His,seq:gtg)
     gene            265..336
                     /locus_tag="ACL3EZ_001025"
     tRNA            265..336
                     /locus_tag="ACL3EZ_001025"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:297..299,aa:Gln,seq:ttg)
     gene            346..429
                     /locus_tag="ACL3EZ_001026"
     tRNA            346..429
                     /locus_tag="ACL3EZ_001026"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:380..382,aa:Leu,seq:caa)
     gene            536..1813
                     /locus_tag="ACL3EZ_001027"
     CDS             536..1813
                     /locus_tag="ACL3EZ_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamylcysteine synthetase"
                     /protein_id="HGR0392612.1"
                     /translation="MSCSIDLLKHRYLKNIKENPELFVGIELEYPVASLEGDATDVEV
                     MKDLFHYLVSTLDLTVAKVDDFGNLIQLVDPISQDAILFEVSYTTIEFAFGKAETIQE
                     VENRFNNYMNVIQRKLAESNHAIVGCGIHPNWDKNENCPVAYPRYQMLMDYLNLSRNI
                     IKSDLHHFPEYGTFICGSQVQLDISKTNYLRVINAFTQIEAAKAYLFANSEFSGADWD
                     TKISRDIFWEESMHGIYPENVGVNARLLNDEADFFDYLNHSAIFTAERDGQTYYFYPI
                     QAGDYLATSEIQAFALNGDEVIIYPQEKDFETHRSYQYQDLTTRGTVEFRSVCTQPLD
                     RTFASAAFHLGLLVNLDKLEAYLETAPFFKVFGYDYKSLRRQFSKKNLTDEEETTIIE
                     FSKDLLLLAEEGLVVRNKEEMTYLQPLREELSL"
     gene            1889..3373
                     /gene="thrC"
                     /locus_tag="ACL3EZ_001028"
     CDS             1889..3373
                     /gene="thrC"
                     /locus_tag="ACL3EZ_001028"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004795 - threonine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0009088 - threonine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HGR0392613.1"
                     /translation="MTLVYQSTRDANNTVTASQAILQGLATDGGLFTPDTYPKVDLNF
                     DKLKDASYQEVAKLVLSAFLDDFTVEELDYCINNAYDSKFDTPAIAPLVKLDGQYNLE
                     LFHGSTIAFKDMALSILPYFMTTAAKKHGLENKIVILTATSGDTGKAAMAGFANVPGT
                     EIIVFYPKDGVSKIQELQMTTQTGDNTHVIAIDGNFDDAQTNVKHMFNDVALREKLTT
                     NKLQFSSANSMNIGRLVPQIVYYVYAYAQLVKTGEIVAGEKVNFTVPTGNFGNILAAF
                     YAKQIGLPVGKLICASNDNNVLTDFFKTRVYDKKREFKVTTSPSMDILVSSNLERLIF
                     HLLGNNAEKTTELMNALNTQGQYKLTDFDAEILDLFAAEYATEEETAAEIKRVCELDS
                     YIEDPHTAVASAVYKKYQSATGDVTKTVIASTASPYKFPVVAVEAVTGKAGLTDFEAL
                     AQLHEISGVAVPPAVDGLEIAPIRHKTTVAAADMQAAVEAYLGL"
     gene            3434..4714
                     /locus_tag="ACL3EZ_001029"
     CDS             3434..4714
                     /locus_tag="ACL3EZ_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HGR0392614.1"
                     /translation="MFKKNKDILNIALPAMGENFLQMLMGMVDSYLVAHLGLIAISGV
                     SVAGNIITIYQAIFIALGAAISSVISKSIGQKDQSKLAYHVTEALKITLLLSFLLGFL
                     SIFAGKEMIGLLGTERDVAESGGLYLSLVGGSIVLLGLMTSLGALIRATHNPRLPLYV
                     SFLSNALNILFSSLAIFVLDMGIAGVAWGTIVSRLVGLVILWSQLKLPYGKPTFGLDK
                     ELLTLALPAAGERLMMRAGDVVIIALVVSFGTEAVAGNAIGEVLTQFNYMPAFGVATA
                     TVMLLARAVGEDDWKRVASLSKQTFWLSLFLMLPLSFSIYVLGVPLTHLYTTDSLAVE
                     ASVLVTLFSLLGTPMTTGTVIYTAVWQGLGNARLPFYATSIGMWCIRIGTGYLMGIVL
                     GWGLPGIWAGSLLDNGFRWLFLRYRYQRYMSLKG"
     gene            4718..5338
                     /locus_tag="ACL3EZ_001030"
     CDS             4718..5338
                     /locus_tag="ACL3EZ_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001172828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HGR0392615.1"
                     /translation="MQKTAFIWDLDGTLLDSYEAILSGIEETFAQFSIPYDKEKVREF
                     IFKYSVQDLLVRVAEDRNLDVEVLNQVRAQSLAEKNAQVVLMPGAREVLAWADESGIQ
                     QFIYTHKGNNAFTILKDLGVESYFTEILTSQSGFVRKPSPEAATYLLDKYQLNSDNTY
                     YIGDRTLDVEFAQNSGIQSINFLESTYEGNHRIQALADISRIFETK"
     gene            5504..6616
                     /locus_tag="ACL3EZ_001031"
     CDS             5504..6616
                     /locus_tag="ACL3EZ_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HGR0392616.1"
                     /translation="MKKRMLLASTVALSFAPVLATQAEEVLWTARSVEQIQNDLTKTD
                     NKTSYTVQYGDTLSTIAEALGVDVTVLANLNKITNMDLIFPETVLTTTVNEAEEVTEV
                     EIQTPQADSSEEVTTATADLTTNQVTVDDQTVQVADLSQPIAEVTKTVIASEEVAPST
                     GTSVPEEQTTETTRPVEEATPQETTPAEKQETQASPQAASAVEVTTTSSEAKEVASSN
                     GATAAVSTYQPEETKIISTTYEAPAAPDYAGLAVAKSENAGLQPQTAAFKEEIANLFG
                     ITSFSGYRPGDSGDHGKGLAIDFMVPERSELGDKIAEYAIQNMASRGISYIIWKQRFY
                     APFDSKYGPANTWNPMPDRGSVTENHYDHVHVSMNG"
     gene            6939..7364
                     /locus_tag="ACL3EZ_001032"
     CDS             6939..7364
                     /locus_tag="ACL3EZ_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000890080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HGR0392617.1"
                     /translation="MLEIQDLLYQLRLSEQASTQLFEKRLGISLTRYQILLFLLEHSP
                     CNQMAVQERLKIDQAALTRHFKILETEGLVERHRNPENQREVLVEAAKYAKEQLVVNP
                     PLQHIRVKEEIESILTEFERTELSRLLNKLVLGIENIEI"
     gene            7375..7734
                     /locus_tag="ACL3EZ_001033"
     CDS             7375..7734
                     /locus_tag="ACL3EZ_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 domain-containing protein"
                     /protein_id="HGR0392618.1"
                     /translation="MSIILTTIVALEHFYIFYLESIATQSDATSRVFNMEKEELAHPS
                     VSSLFKNQGIYKALLGVFLLYVIYFSQNLEIVTIFVLFVIGAATYGSLTADKKIILKQ
                     GGSAILALISILLFKYT"
     gene            7841..8485
                     /gene="pcp"
                     /locus_tag="ACL3EZ_001034"
     CDS             7841..8485
                     /gene="pcp"
                     /locus_tag="ACL3EZ_001034"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016920 - pyroglutamyl-peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HGR0392619.1"
                     /translation="MKVLVTGFEPFGGEKGNPALEAIKGLPAEIHGAEVRWLEVPTVF
                     HKSAQVLEEEMNRYQPDFVLCIGQAGGRTSLTPERVTINQDDACISDNEDNQPIDRPI
                     RPDGASAYFSSLPIKAMVQAIKKEGLPASVSNTAGTFVCSHLMYQALYLVEKKSPYVK
                     AGFMHIPYMMEQVVNRPTTPAMSLVDIRRGIEAAIGAIIEHGDQELKLVGGETH"
     gene            complement(8513..9370)
                     /locus_tag="ACL3EZ_001035"
     CDS             complement(8513..9370)
                     /locus_tag="ACL3EZ_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HGR0392620.1"
                     /translation="MNYPKIDLKTIRQESKHFQADTPRLFLLYILPSMLVILSGFLNP
                     LSRIHGTVLEQPFFSILGQILQTYLFPLLVSFIGTILLTSSVYATLTLMKDSKTEPSV
                     KNSLALFDEERFSQTFLTLLLKRFYLFLWSIPNLLGIYLLFYSSFLAKKFVTLHPEFP
                     NLDLSSVETERFLMVFGLYFLASLILIIVGNILYIPQYYAYSQVEFLLCYSLDLGQVP
                     PRRILKTSRSFMKGYKFQHFVLDLQLLPWYFLNWITFGIASFSLLPYIQCTKIMFYRA
                     VLARKRPKA"
     gene            9500..10642
                     /gene="tgt"
                     /locus_tag="ACL3EZ_001036"
     CDS             9500..10642
                     /gene="tgt"
                     /locus_tag="ACL3EZ_001036"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008479 - tRNA-guanosine(34) queuine
                     transglycosylase activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HGR0392621.1"
                     /translation="MSDSPIKYRLIKKEKHTGARLGEIITPHGTFPTPMFMPVGTQAT
                     VKTQSPEELKEMGSGIILSNTYHLWLRPGDELIARAGGLHKFMNWDQPILTDSGGFQV
                     YSLADSRNITEEGVTFKNHLNGSKMFLSPEKAISIQNNLGSDIMMSFDECPQFYQPYD
                     YVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAHDLVSMDFSGYSI
                     GGLAVGETHEEMNAVLDFTTQLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAQFAEDFTPLDPECDCYTCNNYTRAYLRHLLKADETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREYFVEKYGYNKSGRNF"
     gene            10740..12557
                     /locus_tag="ACL3EZ_001037"
     CDS             10740..12557
                     /locus_tag="ACL3EZ_001037"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HGR0392622.1"
                     /translation="MRIKWFSLIRIIGLLLVLLYHFFQTIFPGGFFGVDVFFTFSGFL
                     ITALLIEEFSKNNEIDLIGFFRRRFYRIVPPVVLMVLVTMPFTFLVRQDYVAGIGGQI
                     AGVLGFMTNFYELLTGGSYESQFIPHLFVHNWSLAVEVHYYILWGLAVWFLSKQAKSN
                     GQLKGMVFLLSAAAFLISFFSMFIGSFLVTSYSSVYFSSLTHVYPFFLGSMLATIVGV
                     RQTTSLVKQLDKIWDLRKTLVVFGGGFGFLVLLTFFVKFTYLFAYLIGFLLASLAALA
                     MILAARVLHEKTHHIQEPKIISFLADTSYAVYLFHWPFYIIFSQLTSNLLAVLLTLIC
                     SYGFASLSFYVLEPWIAGKNTPILQTLRPLPYIHAILVAGTGILTIIVCTVTLLAPQV
                     GAFETDLTVNGLKQAATNIGQTKVMAERADANSLGIADGTMLIGDSVALRANTALQTA
                     LPGAQINAQVSVTTKTANEIMLNNSQNKFLPKTVVIATGVNNPENYKDDWDSIVKNLP
                     KGHHMILVTPYEGDKTKETYAIVEKAAAYMRELAEKTPYITIADWNQVAKEHPEIWAG
                     TDQVHFGSESSTIEAGAKLYADTIATALQTAQDKPVKSK"
     gene            12710..13861
                     /gene="nagA"
                     /locus_tag="ACL3EZ_001038"
     CDS             12710..13861
                     /gene="nagA"
                     /locus_tag="ACL3EZ_001038"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008448 - N-acetylglucosamine-6-phosphate
                     deacetylase activity [Evidence IEA];
                     GO_process: GO:0006044 - N-acetylglucosamine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HGR0392623.1"
                     /translation="MPNYIKADQFFYPHGVRRGGYLELVDGKFGKHVEQIPEGAEVID
                     YTGYSIAPGLVDTHIHGYAGVDVMDNNIEGTLHTMSEGLLSTGVTSFLPTTLTATYEQ
                     LLAVTENLGNHYKEATGAKIRGIYYEGPYFTETFKGAQNPTYMRDPGVEEFHSWQKAA
                     NGLLNKIALAPERDGVEDFVRTVTGEGVTVALGHSNATFDEAKKAVDAGASVWVHAYN
                     GMRGLTHRELGMVGAMYQLPHTYAELICDGHHVDPKACEILIKQKGTENIALITDCMT
                     AGGLEDGDYMLGEFPVVVANGTARLKSTGNLAGSILKLKDGLKNVVEWGIANPHEAVM
                     MASFNPAKSVHIDDVCGQIREGYDADFIVLDKDLELVATYLDGVKRYQA"
     gene            14024..15082
                     /locus_tag="ACL3EZ_001039"
     CDS             14024..15082
                     /locus_tag="ACL3EZ_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
                     /protein_id="HGR0392624.1"
                     /translation="MKAYTYVKPGLASFVDVDKPVIRKPTDAIVRIVKTTICGTDLHI
                     IKGDVPTCQSGTILGHEGIGIVEEVGEGVSNFKKGDKVLISCVCACGKCYYCKKGIYA
                     HCEDEGGWIFGHLIDGMQAEYLRVPHADNTLYHTPEDLSDEALVMLSDILPTGYEIGV
                     LKGKVEPGCSVAIIGSGPVGLAALLTAQFYSPAKLIMVDLDDNRLETALSFGATHKVN
                     SSDPKKAIKEIYDLTDGRGVDVAIEAVGIPETFDFCQKIIGVDGTVANCGVHGKPVEF
                     DLDKLWIRNINVTTGLVSTNTTPQLLKALESHKIEPEKLVTHYFKLSEIEKAYEVFSK
                     AADHHAIKVIIENDISEA"
     gene            15233..15598
                     /locus_tag="ACL3EZ_001040"
     CDS             15233..15598
                     /locus_tag="ACL3EZ_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HGR0392625.1"
                     /translation="MYRVIEMYGDFEPWWFLEGWEEDIVASRKFDQYYDALKYYKTCW
                     FRLEQESPLYKSRSDLMTIFWDPEDQRWCDECDEYLQQYHSLALLQDEQVIPDEKLRS
                     GYEKQTSQERNRSCRMKLK"
     gene            15673..16614
                     /gene="comGA"
                     /locus_tag="ACL3EZ_001041"
     CDS             15673..16614
                     /gene="comGA"
                     /locus_tag="ACL3EZ_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000249584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus ATPase ComGA"
                     /protein_id="HGR0392626.1"
                     /translation="MVQEIAQEIIRSARKKGAQDIYFVPKLDAYELHMRVGDERCKIG
                     SYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYAYDQKMASLRLSTVGDYRGHESL
                     VIRLLHDEEQDLHFWFQDIEELGKQYRQRGLYLFAGPVGSGKTTLMHELSKSLFKGQQ
                     VMSIEDPVEIKQDDMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDSETARAVV
                     RASLTGATVFSTIHAKSIRGVYERLLELGVSEEELAVVLQGVCYQRLIGGGGIVDFAS
                     RDYQEHQAAKWNEQIDQLLKDGHITSLQAETEKISYS"
     gene            16562..17578
                     /gene="comGB"
                     /locus_tag="ACL3EZ_001042"
     CDS             16562..17578
                     /gene="comGB"
                     /locus_tag="ACL3EZ_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000355375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus assembly protein ComGB"
                     /protein_id="HGR0392627.1"
                     /translation="MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETISFLD
                     RSALLDKQCVTQMRAGLSQGKSFSEMMESLGCSSAIVTQLSLAEVHGNLHLSLGKIEE
                     YLDNLAKVKKKLIEVATYPLILLFFLLLIMLGLRNYLLPQLDSSNIATRIIGNLPQIF
                     LGMVGLVSVLALLALTFYKRSSKMSVFSILARLPFIGIFVQTYLTAYYAREWGNMISQ
                     GMELTQIFQMMQEQGSQLFKEIGQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGE
                     VKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIVLLYAAMLMPMYQNM
                     EVNF"
     gene            17580..17906
                     /gene="comGC"
                     /locus_tag="ACL3EZ_001043"
     CDS             17580..17906
                     /gene="comGC"
                     /locus_tag="ACL3EZ_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="comG operon protein ComGC"
                     /protein_id="HGR0392628.1"
                     /translation="MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKE
                     AVNDKGKAAVVKVVESQAELYSLEKNEDASLSKLQADGRITEEQAKAYKEYHDKNGVA
                     NRKVND"
     gene            17899..18303
                     /gene="comGD"
                     /locus_tag="ACL3EZ_001044"
     CDS             17899..18303
                     /gene="comGD"
                     /locus_tag="ACL3EZ_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGD"
                     /protein_id="HGR0392629.1"
                     /translation="MIKAFTMLESLLALSLVSILALGLSGSVQSTFAAVEEQIFFMEF
                     EELYRETQKRSVASQQKTSLNLDGQTLSNGSQKLPVPKGIQAPSGQSITFDRAGGNSS
                     LAKVEFQTSKGAIRYQLYLGNGKIKRIKETKN"
     gene            18266..18568
                     /gene="comGE"
                     /locus_tag="ACL3EZ_001045"
     CDS             18266..18568
                     /gene="comGE"
                     /locus_tag="ACL3EZ_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGE"
                     /protein_id="HGR0392630.1"
                     /translation="MEKLNALRKQKIRAVILLEAVVALAIFASIATLLLGQIQKNRQE
                     EAKILQKEEVLRVAKMALQTGQNQVSINGVEIQVFSSEKGLEVYHGSEQLLAIKEP"
     gene            18531..18992
                     /gene="comGF"
                     /locus_tag="ACL3EZ_001046"
     CDS             18531..18992
                     /gene="comGF"
                     /locus_tag="ACL3EZ_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000250539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGF"
                     /protein_id="HGR0392631.1"
                     /translation="MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQAMSQLLI
                     SEVRYQQQSEQKEWLLFVDQLEVELDRSQFEKVEGNRFYMKQDGKDIAIGKSKSDDFR
                     KTDASGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEES"
     gene            18970..19383
                     /gene="comGG"
                     /locus_tag="ACL3EZ_001047"
     CDS             18970..19383
                     /gene="comGG"
                     /locus_tag="ACL3EZ_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGG"
                     /protein_id="HGR0392632.1"
                     /translation="MWKKKKVKAGVLLYAVTMAAIFSLLLQFYLNRQVAHYQDYALNK
                     EKLVAFAMAKRTKDKAEQESGEQVFNLGQVSYQNKKTSLVTTVRTDKSQYEFLFPSVK
                     IKEEKRDKKEEVATDSSEKAEKKKSEEKPEKKENS"
     gene            19520..20113
                     /locus_tag="ACL3EZ_001048"
                     /pseudo
     CDS             19520..20113
                     /locus_tag="ACL3EZ_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679792.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
     gene            20174..21127
                     /locus_tag="ACL3EZ_001049"
     CDS             20174..21127
                     /locus_tag="ACL3EZ_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGR0392633.1"
                     /translation="MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGET
                     ELNQVKDNNQALKRLALRKEEWLKTYQFLLMKAGETEPLQANHQFTPDAIALLLVFIV
                     EELFKEEEITILEMGSGMGILGATFLTSLDKKVDYLGMEVDDLLIDLAASMADVIGLQ
                     AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGF
                     KYLKSDGYAIFLAPSDLLTSPQSDLLKVWLKEEASLVAMISLPENLFANAKQSKTIFI
                     LQKKNEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI"
     gene            21178..22368
                     /locus_tag="ACL3EZ_001050"
     CDS             21178..22368
                     /locus_tag="ACL3EZ_001050"
                     /EC_number="2.7.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008776 - acetate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006085 - acetyl-CoA biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HGR0392634.1"
                     /translation="MTKTIAINAGSSSLKWQLYLMPEEKVLAKGLIERIGLKDSISTV
                     KFDGRSEQQILDIENHTQAVKILLDDLIRFDIIKAYDEITGVGHRVVAGGEYFKESTV
                     VEGDVLEKVEELSLLAPLHNPANAAGVRAFKELLPDITSVVVFDTSFHTSMPEKAYRY
                     PLPTKYYTENKVRKYGAHGTSHQFVAGEAAKLLGRPLEDLKLITCHIGNGGSITAVKA
                     GKSVDTSMGFTPLGGIMMGTRTGDIDPAIIPYLMQYTEDFNTPEDISRVLNRESGLLG
                     VSANSSDMRDIEAAVAEGNHEASLAYEMYVDRIQKHIGQYLAVLNGADAIVFTAGVGE
                     NAESFRRDVISGISWFGCDVDDEKNVFGVTGDISTEAAKIRVLVIPTDEELVIARDVE
                     RLKK"
     gene            22369..22500
                     /locus_tag="ACL3EZ_001051"
     CDS             22369..22500
                     /locus_tag="ACL3EZ_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0392635.1"
                     /translation="MKLKKYSIQGVGKVIFPASFSDEIVQNLAMIGFFEKYGIIVVI"
     gene            22517..22888
                     /gene="rnpA"
                     /locus_tag="ACL3EZ_001052"
     CDS             22517..22888
                     /gene="rnpA"
                     /locus_tag="ACL3EZ_001052"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0004526 - ribonuclease P activity
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HGR0392636.1"
                     /translation="MKKNFRVKREKDFKAIFKEGTSFANRKFVVYQLENQKNHFRVGL
                     SVSKKLGNAVTRNQIKRRIRHIIQNAKGSLVEDVDFVVIARKGVETLGYAEMEKNLLH
                     VLKLSKIYREGNGSEKETKVD"
     gene            22863..23687
                     /locus_tag="ACL3EZ_001053"
     CDS             22863..23687
                     /locus_tag="ACL3EZ_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HGR0392637.1"
                     /translation="MKKKLKLTSLLGLSLLIMTACATNGVTSDITAESADFWSKLVYF
                     FAEIIRFLSFDISIGVGIILFTVLIRTVLLPVFQVQMVASRKMQEAQPRIKALREQYP
                     GRDMESRTKLEQEMRKVFKEMGVRQSDSLWPILIQMPVILALFQALSRVDFLKTGHFL
                     WINLGSVDTTLVLPILAAVFTFLSTWLSNKALSERNGATTAMMYGIPVLIFIFAVYAP
                     GGVALYWTVSNAYQVLQTYFLNNPFKIIAEREAVVQAQKDLENRKRKAKKKAQKTK"
     gene            23706..24692
                     /gene="jag"
                     /locus_tag="ACL3EZ_001054"
     CDS             23706..24692
                     /gene="jag"
                     /locus_tag="ACL3EZ_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000260012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding cell elongation regulator Jag/EloR"
                     /protein_id="HGR0392638.1"
                     /translation="MVVFTGSTVEEAIQKGLKELDIPRMKAHIKVISREKKGFLGLFG
                     KKPAQVDIEAISETTVVKANQQVVKGVPKKINDLNEPVKTVSEETVDLGHVVNAIKKI
                     EEEGQGISDEVKAEILKHERHASTILEETGHIEILNELQIEEAMREEAGADDLETEQD
                     QTENQDLKEMGLKVEQSYDIAQVATDVTAYVQAIVDDMDVEATLSNDYNRRSINLQID
                     TNEPGRIIGYHGKVLKALQLLAQNYLYNRYSKTFYVTINVNDYVEHRAEVLQTYAQKL
                     ANRVLEEGRSHKTDPMSNSERKIIHRIISRMDGVTSYSEGDEPNRYVVVDTE"
     gene            24743..25366
                     /locus_tag="ACL3EZ_001055"
     CDS             24743..25366
                     /locus_tag="ACL3EZ_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HI_0552 family protein"
                     /protein_id="HGR0392639.1"
                     /translation="MLNKIRDYLDFSGLQYRSPDKAGAEREKMLAFRHKGQEARKAFT
                     ELAKAFQASHPEWQLQQTSQWMNQAQCLRPHFWVYLQRDGQVTEPMMALRLYGTSTDF
                     GISLEVSFIERKKDEQTLGKQTKVLDIPTVKGIYYLTYSNGQSQRWEANEEKRRTLRE
                     KVRSQEVRKVLVKVDVPMTENSSEEEIVEGLLKSYSKILPYYLATRK"
     gene            25507..26964
                     /locus_tag="ACL3EZ_001056"
     CDS             25507..26964
                     /locus_tag="ACL3EZ_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HGR0392640.1"
                     /translation="MEVVSSVLNWFSSNILQNPAFFVGLLVLIGYALLKKPAHDVFSG
                     FVKATVGYMLLNVGAGGLVTTFRPILAALNYKFQIGAAVIDPYFGLAAANNKIAAEFP
                     DFVGTATTALLIGFGINILLVALRKITKVRTLFITGHIMVQQAATVSLMVLFLVPQLR
                     NAYGTAAIGIICGLYWAVSSNMTVEATQRLTGGGGFAIGHQQQFAIWFVDKVAGRFGK
                     KEESLDNLKLPKFLSIFHDTVVASATLMLVFFGAILLILGPDIMSNKEVITSGTLFNP
                     AKQDFFMYIIQTAFTFSVYLFVLMQGVRMFVSELTNAFQGISNKLLPGSFPAVDVAAS
                     YGFGSPNAVLSGFTFGLIGQLITIVLLIVFKNPILIITGFVPVFFDNAAIAVYADKRG
                     GWKAAVILSFISGVLQVALGALCVALLDLASYGGYHGNIDFEFPWLGFGYIFKYLGIV
                     GYVLVCLFLLVIPQLQFAKAKDREKYYNGEVQEEA"
     gene            26987..27268
                     /locus_tag="ACL3EZ_001057"
     CDS             26987..27268
                     /locus_tag="ACL3EZ_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGR0392641.1"
                     /translation="MVKVLAACGNGMGSSMVIKMKVENALRKLNQTDFTVNSCSVGEA
                     KGLAVGYDIVIASLHLIQELEGRTNGKLIGLDNLMDDKEITEKLSQALQ"
     gene            27344..27829
                     /locus_tag="ACL3EZ_001058"
     CDS             27344..27829
                     /locus_tag="ACL3EZ_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002267837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGR0392642.1"
                     /translation="MNLKQALIDNDSIRLGLEANNWKEAVKVAVDPLIESGAILPEYY
                     DAIIESTEEYGPYYILMPGMAMPHARPEAGVQSDAFSLITLQNPVVFSDGKEVSVLLA
                     LAATSSKIHTSVAIPQIIALFELEDSIARLQACQTKEDVLAMIEESKDSPYLEGLDLE
                     S"
     gene            27846..28511
                     /locus_tag="ACL3EZ_001059"
     CDS             27846..28511
                     /locus_tag="ACL3EZ_001059"
                     /EC_number="4.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HGR0392643.1"
                     /translation="MTKRIPNLQVALDHSDLQGAIKAAVSVGQEVDIIEAGTVCLLQV
                     GSELAEVLRSLFPDKIIVADTKCADAGGTVAKNNAVRGADWMTCICCATIPTMEAALK
                     AIKTERGERGEIQIELYGDWTFEQAQLWLDAGISQAIYHQSRDALLAGETWGEKDLNK
                     VKKLIDMGFRVSVTGGLDVDTLKLFEGVDVFTFIAGRGITEAADPAGAARAFKDEIKR
                     IWG"
     gene            28515..29378
                     /locus_tag="ACL3EZ_001060"
     CDS             28515..29378
                     /locus_tag="ACL3EZ_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016861 - intramolecular oxidoreductase
                     activity, interconverting aldoses and ketoses [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HGR0392644.1"
                     /translation="MVRPIGIYEKATPTHCTWLERLNFAKELGFDFVEMSIDERDERL
                     ARLDWSKEERLEVVKAIYETGVRIPSICFSGHRRYPLGSKDPVLEEKSLELMKKCIEL
                     AQDLGVRTIQLAGYDVYYEEKSPQTRQRFIKNLRKACDWAEEAQVVLAIEIMDDPFIN
                     SIEKYLAIEKEIDSPFLFVYPDIGNVSAWHNDIYSEFYLGHHAIAALHLKDTYAVTES
                     SKGQFRDVPFGQGCVKWEEAFDILKETNYNGPFLIEMWSENCETVEETRAAIQEAQAF
                     LYPLIKKAGLM"
     gene            29380..30084
                     /locus_tag="ACL3EZ_001061"
     CDS             29380..30084
                     /locus_tag="ACL3EZ_001061"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HGR0392645.1"
                     /translation="MNQVINAMRKRVCDANQSLPKHGLVKFTWGNVSEVNRELGVIVI
                     KPSGVDYDELTPENMVVTDLDGKILEGDLRPSSDLPTHVQLYKAWSEIGSVVHTHSTE
                     AVGWAQAGRDIPFYGTTHADYFYGSIPCARSLTKDEVEVAYEKDTGLVIVEEFEHRGL
                     NPVEVPGIVVRNHGPFTWGKNPENAVYHSVVLEEVSKMNRFTEQINPRVGPAPQYILE
                     KHYQRKHGPNAYYGQK"
     gene            30261..31934
                     /locus_tag="ACL3EZ_001062"
     CDS             30261..31934
                     /locus_tag="ACL3EZ_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HGR0392646.1"
                     /translation="MVLDKASCDLLQYLMDQETSKTIMAISKDLKESRRKIYYHIDKI
                     NAALVDEALHIISIPRIGIHLTEEQRDACCKLLSEVDSYDYIMSAHERMMIMLLWIGI
                     SKERITIEKLIELTEVSRNTVLNDLNSIRYQLTLEQYQVILQVSKSQGYHLHAHPLNK
                     IQYLQSLLYHIFMEENATFVSILEDKMKERLDDECLLSVEMNQFFKEQVPLVEQDLGK
                     KINHHEITFMLQVLPYLLLSCHNVEQYQERHQDIEKEFSLIRKRIEYQVSKKLGERLF
                     QKFEISLSGLEVSLVAVLLLSYRKDLDIHAESDDFRQLKLALEEFIWYFESQIRMEIE
                     NKDDLLRNLMIHCKALLFRKTYGIFSKNPLTKQIRSKYGELFLVTRKSAEILEGAWFI
                     RLTDDDIAYLTIHIGGFLKYTPSSQKNMKKVYLVCDEGVAVSRLLLKQCKLYFPNEQI
                     DTVFTTEQFKSVEDIAQVDVVITTNDDLDSRFPILRVNPILEAEDILKMLDYLKHNIF
                     RNKSKSFSENLSSLISSYIVDSKLASKFQEEVQTLINQEIVVQAFLEDI"
     gene            32046..33137
                     /gene="ulaG"
                     /locus_tag="ACL3EZ_001063"
     CDS             32046..33137
                     /gene="ulaG"
                     /locus_tag="ACL3EZ_001063"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030145 - manganese ion binding [Evidence
                     IEA];
                     GO_function: GO:0035460 - L-ascorbate 6-phosphate
                     lactonase activity [Evidence IEA];
                     GO_process: GO:0019854 - L-ascorbic acid catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HGR0392647.1"
                     /translation="MPNVKEITRESWILATFPEWGTWLNEEIEEEVVPEGNFAMWWLG
                     NCGTWIKTPAGANVVMDLWSNRGKSTKKVKDMVRGHQMANMAGVRKLQPNLRVQPMVI
                     DPFAINELDYYLVSHFHSDHIDPYTAAAILNNSKLEHVKFIGPYHCGRIWEGWGVPKE
                     RIIVVKPGDTIELKDMKIHAVESFDRTCLVTLPVNGADETGGELAGLAVTDEEMAQKA
                     VNYIFETPGGTIYHGADSHFSNYFAKHGKDFKIDVALNNYGENPVGIQDKMTSIDLLR
                     MAENLRTKVIIPVHYDIWSNFMASTNEILELWKMRKDRLQYDFHPFIWEVGGKYTYPQ
                     DQHLVEYHHPRGFDDCFEQDSNIQFKALL"
     gene            33251..35227
                     /gene="tkt"
                     /locus_tag="ACL3EZ_001064"
     CDS             33251..35227
                     /gene="tkt"
                     /locus_tag="ACL3EZ_001064"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004802 - transketolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HGR0392648.1"
                     /translation="MSNLSVNAIRFLGIDAINKANSGHPGVVMGAAPMAYSLFTKQLH
                     INPAQPNWINRDRFILSAGHGSMLLYALLHLSGFEDVSMDEIKSFRQWGSKTPGHPEF
                     GHTAGIDATTGPLGQGISTATGFAQAERFLAAKYNREGYNIFDHYTYVICGDGDLMEG
                     VSSEAASYAGLQKLDKLVVLYDSNDINLDGETKDSFTESVRDRYNAYGWHTALVENGT
                     DLEAIHAAIETAKASGKPSLIEVKTVIGYGSPNKQGTNAVHGAPLGADETASTRQALG
                     WDYEPFEIPEQVYADFKEHVADRGASAYQAWTKLVADYKEAHPELAAEVEAIIDGRDP
                     VEVTPADFPALENGFSQATRNSSQDALNVVAAKLPTFLGGSADLAHSNMTYIKTDGLQ
                     DDTNRLNRNIQFGVREFAMGTILNGMALHGGLRVYGGTFFVFSDYVKAAVRLSALQGL
                     PVTYVFTHDSIAVGEDGPTHEPVEHLAGLRAMPNLNVFRPADARETQAAWYLAVTSEK
                     TPTALVLTRQNLTVEDGTDFDKVAKGAYVVYENAADFDTILIATGSEVNLAVSAAKEL
                     ASQGEKIRVISMPSTDVFDKQNAAYKEEILPNAVRRRVAVEMGASQNWYKYVGLDGAV
                     LGIDTFGASAPAPKVLAEYGFTVENLVKVVRNLK"
     gene            35344..35643
                     /gene="yajC"
                     /locus_tag="ACL3EZ_001065"
     CDS             35344..35643
                     /gene="yajC"
                     /locus_tag="ACL3EZ_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HGR0392649.1"
                     /translation="MNPNITFLIMLVGMMALMFFMQRSQKKQAQKRMESLNKLQKGYE
                     VITIGGLYGTVDEVDTEKGTIVLDVDGVYLTFELAAIKTVLPLKETASLEGAIEK"
     gene            35689..36117
                     /locus_tag="ACL3EZ_001066"
     CDS             35689..36117
                     /locus_tag="ACL3EZ_001066"
                     /EC_number="3.1.3.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight
                     protein-tyrosine-phosphatase"
                     /protein_id="HGR0392650.1"
                     /translation="MKKLVFVCLGNICRSPMAEFVMKSMTDNYEIQSRATSSWEHGNP
                     IHKGTQGIFQEYEIPYDKNKTSLQISKEDFEAFDYIIGMDASNISDLRQMCPVDCQDK
                     IYSFSSESVPDPWYTGDFEETYRRVQEGCQAWLERLEKES"
     gene            36119..36529
                     /locus_tag="ACL3EZ_001067"
     CDS             36119..36529
                     /locus_tag="ACL3EZ_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000427064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MORN repeat-containing protein"
                     /protein_id="HGR0392651.1"
                     /translation="MENLTNFYEKYRVYLTRPRLELLAVVTIVFCAVLVFFLNIPGKG
                     VLKLDNGTIVYDGSLVRGKMNGQGTITFQNGDQYTGGFNNGAFNGKGTFQSKEGWTYE
                     GDFVNGQAEGKGKLTTEQEVVYEGTFKQGVFQQK"
     gene            36829..39480
                     /gene="adhE"
                     /locus_tag="ACL3EZ_001068"
                     /gene_synonym="adhC"
     CDS             36829..39480
                     /gene="adhE"
                     /locus_tag="ACL3EZ_001068"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004022 - alcohol dehydrogenase (NAD+)
                     activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006066 - alcohol metabolic process
                     [Evidence IEA];
                     GO_process: GO:0015976 - carbon utilization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HGR0392652.1"
                     /translation="MADKKTVTPEEKKLVAEKHVDELVQKALVALEEMRKLDQEQVDY
                     IVAKASVAALDAHGELALHAFEETGRGVFEDKATKNLFACEHVVNNMRHTKTVGVIEE
                     DDVTGLTLIAEPVGVVCGITPTTNPTSTAIFKSLISLKTRNPIVFAFHPSAQESSAHA
                     ARIVRDAAIAAGAPENCVQWITQPSMEATSALMNHEGVATILATGGNAMVKAAYSCGK
                     PALGVGAGNVPAYVEKSANIRQAAHDIVMSKSFDNGMVCASEQAVIIDKEIYDEFVAE
                     FKSYHTYFVNKKEKALLEEFCFGVKANSKNCAGAKLNADIVGKPATWIAEQAGFTVPE
                     GTNILAAECKEVGENEPLTREKLSPVIAVLKSESREDGITKARQMVEFNGLGHSAAIH
                     TADEELTKEFGKAVKAIRVICNSPSTFGGIGDVYNAFLPSLTLGCGSYGRNSVGDNVS
                     AINLLNIKKVGRRRNNMQWMKLPSKTYFERDSIQYLQKCRDVERVMIVTDHAMVELGF
                     LDRIIEQLDLRRNKVVYQIFADVEPDPDITTVNRGTEIMRAFKPDTIIALGGGSPMDA
                     AKVMWLFYEQPEVDFRDLVQKFMDIRKRAFKFPLLGKKTKFIAIPTTSGTGSEVTPFA
                     VISDKANNRKYPIADYSLTPTVAIVDPALVLTVPGFVAADTGMDVLTHATEAYVSQMA
                     SDYTDGLALQAIKLVFENLESSVKNADFHSREKMHNASTIAGMAFANAFLGISHSMAH
                     KIGAQFHTIHGRTNAILLPYVIRYNGTRPAKTATWPKYNYYRADEKYQDIARMLGLPA
                     STPEEGVESYAKAVYELGERIGIQMNFRDQGIDEKEWKEHSRELSFLAYEDQCSPANP
                     RLPMVDHMQEIIEDAYYGYKERPGRRK"
     gene            complement(40393..40701)
                     /locus_tag="ACL3EZ_001069"
     CDS             complement(40393..40701)
                     /locus_tag="ACL3EZ_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HGR0392653.1"
                     /translation="MTEEMEYICFQLIANSGAAKSSFIEAIQLAKAGNLKEAKIKVEE
                     AEDSLVEAHKIHSNLIQKEATGEKIGFSLLFMHAEDQMASTEIIQLLSKEFIDLYQNK
                     "
     gene            complement(40698..41006)
                     /locus_tag="ACL3EZ_001070"
     CDS             complement(40698..41006)
                     /locus_tag="ACL3EZ_001070"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGR0392654.1"
                     /translation="MKQILLVCNAGMSTSMLVKKMQQSATERGIEISIQAKSMTEAKK
                     NIHEADVILIGPQIRYELLAVKEIAGNIPVDTIDMRDYGMMNGAKVLEQALAWIGEIR
                     "
     gene            complement(41011..42306)
                     /locus_tag="ACL3EZ_001071"
     CDS             complement(41011..42306)
                     /locus_tag="ACL3EZ_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000798148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HGR0392655.1"
                     /translation="MKNSKFIDQFATFAGKLGNQIHLKTLRDAFVTVMPLYILAGLIV
                     LLNNTVFKWIFQGDTLTRFQYWGITIANGTLSISGMIIAVMVGYFLAKNRDFENPLAA
                     SMLSLVSLIVMMPNTVSVVPDGAKDAVNISGVLSFNNTGTGAMFAGVIVAIIATELFI
                     ELSNVKALQMNLGENIPPAVSRSFSVLLPVMTVISLFGVVSALLFNITGMNLISIITI
                     FIQEPIRHIGTSLIGVIIIYSLGNMLWLFGIHQAVIYSAILEPLLLINITENITAANN
                     GQAIPHIINLSQIQTFALMGGSGSTLCLLIATFLVSRNAVSKNVAKLSFGPGIFNINE
                     PVLFGYPIVYNISLAIPFITVPVLGILISYLATVTGFMSPAFIQVPWTTPVFLNAWLA
                     TAGDVRAVLVQFIIFALGVLLYIPFIKVNDKVVEQEMEG"
     gene            complement(42324..43733)
                     /locus_tag="ACL3EZ_001072"
     CDS             complement(42324..43733)
                     /locus_tag="ACL3EZ_001072"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HGR0392656.1"
                     /translation="MKKKLVFPNLFWWGAASSGPQTEGQYGKVHENVMDYWFKTHPED
                     FFDNVGPLVASNFFHTYTEDFHLMKEIGVNSFRTSIQWSRLIKNLETGEPDPKGIAFY
                     NAIIEEAKKNQMDLVMNLHHFDLPVELLQKYGGWESKHVVELFVKFAKTAFTCFGDKV
                     HYWTTFNEPMVIPEAGYLYAFHYPNLKGKGKEAVQVIYNLNLASAKVIQLYRSLGLDG
                     KIGIILNLTPAYPRSNSPEDLEASRFTDDFFNKVFLNPAVKGTFPERLVKQLERDGVL
                     WSHTEKELQLMKSNTVDFLGVNYYHPKRVQAQANPEEYQTPWMPDQYFKEYEWPERRM
                     NPYRGWEIFPKAIYDIAMIVKKEYGNIPWFISENGMGVENEARFIGENGVIDDVYRIE
                     FYEEHLRWLHKAIEEGSHCFGYHAWTAFDCWSWNNAYKNRYGFISVDLETQKRTIKRS
                     GRWYRKVSDNNGFEVEIEE"
     gene            43891..44619
                     /locus_tag="ACL3EZ_001073"
     CDS             43891..44619
                     /locus_tag="ACL3EZ_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HGR0392657.1"
                     /translation="MSTKYLFIYNEIREKILCNKYTMNEQLPDEMTLAKQFACSRMTI
                     KKALDLLVSEGLIFRKRGQGTFVLSRGSSKRKLIVPERDIRGLTKISEDAHSTIDSRI
                     IHFKLEFANEFLAEKLQVALQSPVYNIYRLRIIDGKPYVLEQTYMSTDVIPGITEDIL
                     QKSIYNYIEGKLGLHIASATKILRASSSSENEQHYLQLLPTEPVFEVEQVAYLDNGTP
                     FEYSISRHRYDLFEFNSFALRHSS"
     gene            45078..45272
                     /locus_tag="ACL3EZ_001074"
     CDS             45078..45272
                     /locus_tag="ACL3EZ_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HGR0392658.1"
                     /translation="MKGKEYENRTVSFAISSKGEKMKVENISYRVDHRKLFDNISFDT
                     SSSDVTLITGKNGTGKSTLL"
     gene            complement(45394..45560)
                     /locus_tag="ACL3EZ_001075"
                     /pseudo
     CDS             complement(45394..45560)
                     /locus_tag="ACL3EZ_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558122.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(45638..46948)
                     /locus_tag="ACL3EZ_001076"
     CDS             complement(45638..46948)
                     /locus_tag="ACL3EZ_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HGR0392659.1"
                     /translation="MIHLIMISAIALAIGIGYRTKINIGLLAIAFSYLIATTLMGLSP
                     KELLHFWPTSLFFTIFSVSLFYNVATTNGTLDVLAQHILYRTRTHPNALYMILYLMAT
                     LLSALGAGFFTTMAVCCPLAITLCQKADKHPLIGAQAVNWGASGGANLITSSSGIVFQ
                     GLFKQMGWEEQAFSLGNHIFIVSIIYPLIVLLLLSCYSHYSKGRTNSSLTIDQPPLLS
                     KVQRQTTLLMISSMVLVWLFPLLHLIFPNIAWIATYQKTFDIGFVSILMVCLALRLKL
                     GKQEAILAKVPWATIIMLCGMSLLMSLAVKSGLVTLIGHLMTTTIPHFWLPLFFCVIA
                     GVMSLFSSTLSVVAPALFPIIAIISAQNPQIDIHLLTTATVIGALSTNISPFSSAGSL
                     IQLSLPNIEERGLAFKKQIILGVPISLSLGLLTTWILILLASLS"
     gene            47185..48057
                     /gene="nadC"
                     /locus_tag="ACL3EZ_001077"
     CDS             47185..48057
                     /gene="nadC"
                     /locus_tag="ACL3EZ_001077"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004514 - nicotinate-nucleotide
                     diphosphorylase (carboxylating) activity [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HGR0392660.1"
                     /translation="MSIISTDLTPFQIDDTLKAALREDVHSEDYSTNAIFDHHGQAKV
                     SLFAKEAGVLAGLTVFQRVFTLFDAEVTFQNPHQFKDGDRLTSGDLVLEIIGSVRSLL
                     TCERVALNFLQHLSGIASMTAAYVEALGDDCIKVFDTRKTTPNLRLFEKYAVRVGGGY
                     NHRFNLSDAIMLKDNHIAAVGSVQKAIAQARAYAPFVKMVEVEVESLAAAEEAAAAGA
                     DIIMLDNMSLEQIEQAITLIAGRSRIECSGNIDMTTISRFRGLAIDYVSSGSLTHSAK
                     SLDFSMKGLTYLDV"
     gene            48188..>48258
                     /locus_tag="ACL3EZ_001078"
     CDS             48188..>48258
                     /locus_tag="ACL3EZ_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001839528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 transposase-related protein"
                     /protein_id="HGR0392661.1"
                     /translation="MAYSIDFRKKVLSYCERTGSITEA"
BASE COUNT        14760 a         8582 c        10535 g        14381 t
ORIGIN      
        1 tatattttgg aagggtagcg aagaggctaa acgcggcgga ctgtaaatcc gctccttcgg
       61 gttcgggggt tcgaatccct ccccttccat tttacgggca tagtttaaag gtagaactaa
      121 ggtctccaaa accttcagtg tgggttcaat tcctactgcc cgtgttaata gaattatggc
      181 gggtgtggtg aagtggttaa cacaccagat tgtggctctg gcatgcgtgg gttcgatccc
      241 catcactcgc ctattttata ttattggggt atagccaagc ggtaaggcaa gggactttga
      301 ctccctcatg cgttggttcg aatccagcta ccccagttac tatttgccgg cgtggcggaa
      361 ttggcagacg cgctggactc aaaatccagt gtccgcaagg acgtgccggt tcgaccccgg
      421 ccgccggtat agtatagtgt taggaacgtt gttattcttc gttccttttt tatattattt
      481 ttggtataat tatagttatt caaattttat ttagattaag aaagtgtagg ggagtatgtc
      541 ttgttctatc gatttattaa aacatcggta tttgaaaaat attaaagaaa atcctgaatt
      601 gtttgtcgga attgagttgg agtatcctgt tgcaagttta gaaggggatg ctacagatgt
      661 tgaagttatg aaggatctat ttcattattt agtttctact ttggatctca ccgtagcaaa
      721 ggtagatgat tttggcaatc tgatccagtt agtagatccg ataagtcagg atgctatttt
      781 atttgaagtt tcctatacaa cgattgagtt tgcatttggt aaggctgaaa cgattcaaga
      841 ggtcgaaaat cgtttcaata attatatgaa tgtaattcag agaaagttag ctgaatcaaa
      901 tcatgctatt gttggctgtg gtatccatcc caactgggat aaaaatgaga attgtccagt
      961 ggcttatcca cgctatcaga tgttgatgga ttatttgaat ttgagtagaa atattattaa
     1021 atcagattta catcatttcc ctgaatatgg tacttttatc tgtgggagcc aggttcagct
     1081 ggatatttca aaaaccaact acttacgggt gattaatgct tttactcaaa ttgaagcggc
     1141 taaggcttat ttatttgcaa actctgaatt ttcgggtgcg gattgggata cgaaaatttc
     1201 aagggatatt ttctgggaag aatctatgca tggtatctat ccagagaatg ttggggtcaa
     1261 tgctagactc cttaatgatg aagctgattt ttttgactat ctaaatcatt ctgcgatttt
     1321 tactgcggaa cgtgatgggc agacctatta tttttatcct attcaggctg gggactattt
     1381 ggctacgtcc gaaatccaag catttgctct gaatggggat gaggttatta tttaccccca
     1441 agagaaggat tttgaaactc atcgtagtta ccagtaccaa gatttaacga ctcgaggaac
     1501 agttgagttt cgtagtgtgt gtacacagcc acttgatagg acttttgctt ctgcagcttt
     1561 tcacttggga ttattggtta atttagacaa gttagaagct tacttagaaa cagcaccttt
     1621 ctttaaagta tttggttatg attacaagtc tttaaggaga caattttcta agaaaaatct
     1681 tacagatgag gaagaaacta cgattattga attttccaaa gacttactcc tactagctga
     1741 ggagggacta gtggtgagaa ataaggaaga aatgacctat ttacagcctt tgagagaaga
     1801 attgagccta taatttctct tataaaggga gaattttctg aaaaatcatg atataatgga
     1861 cgagactata gataaaggat agagagtaat gacattagtt tatcaatcaa cgcgtgatgc
     1921 caacaataca gtaactgcca gccaagcaat tttgcaaggt ttggcgacgg acggcggttt
     1981 gtttacaccg gatacttatc caaaggtaga tttgaacttt gacaaattga aagatgcttc
     2041 ttaccaggaa gttgctaagc tagttttgtc agcattttta gatgacttta cagttgagga
     2101 gttggactac tgtatcaaca atgcctacga tagcaaattt gatactccag ctattgcacc
     2161 attagtgaaa ttagatgggc aatacaattt ggaacttttc catggttcaa cgattgcctt
     2221 taaggatatg gccttgtcta ttttgccata ctttatgacg actgctgcta agaaacatgg
     2281 tttggagaac aagattgtta tcttgacagc gacatctggt gacacgggga aagctgctat
     2341 ggcggggttt gcgaatgtgc ctggtactga gattatcgtc ttttatccaa aggatggtgt
     2401 cagcaagatt caagagttac aaatgaccac tcagactggc gacaatactc atgttattgc
     2461 tattgatggt aactttgacg atgcgcaaac aaatgtgaag cacatgttta acgacgtggc
     2521 tcttcgtgaa aaattgacta ccaacaagtt gcaattttca tcagctaact ctatgaacat
     2581 tggtcgtctg gtgccacaaa ttgtttatta tgtttatgct tacgctcaat tggttaagac
     2641 tggtgaaatt gtagctggtg aaaaggttaa cttcacagta ccaacaggaa actttggaaa
     2701 tatcttggct gccttttatg ccaaacaaat tggtttgcca gttggtaaat taatctgtgc
     2761 ttcaaatgac aacaatgttt tgacagactt ctttaaaaca cgtgtctatg acaaaaaacg
     2821 tgagtttaag gtaacaacca gcccatctat ggatatcttg gtatcttcaa acttggagcg
     2881 cttgattttc catcttttgg gaaataatgc tgaaaagaca actgaactta tgaatgcctt
     2941 gaacacgcaa ggacaatata agttgacaga ctttgatgca gagattttgg acctctttgc
     3001 agctgaatat gcgactgagg aagaaacggc agcagagatc aagcgtgttt gtgagttaga
     3061 ttcttatatc gaggaccctc atacagctgt tgcttcagca gtttataaaa aataccaatc
     3121 ggccactgga gatgtaacta agacagtgat tgcttcaaca gctagtccat acaagttccc
     3181 agtagttgca gtagaagctg taactggaaa agcaggttta acagactttg aagccttggc
     3241 tcaattacat gaaatctcag gcgttgcagt gccaccagca gttgatgggc ttgaaatagc
     3301 tccaattcgt cacaagacaa cagtggcagc tgctgacatg caagcagcgg ttgaggctta
     3361 tttaggactt taagacagag ggagcaaact cggttgggaa accaactgag tttcttttca
     3421 tcaggaggag agattgttta agaaaaataa agacattctt aatattgcat tgccagctat
     3481 gggtgaaaac tttttgcaga tgctaatggg aatggtggac agttatttgg ttgctcattt
     3541 aggattgata gctatttcag gggtttcagt agctggtaat attatcacca tttatcaggc
     3601 gattttcatc gctctgggag ctgctatttc cagtgttatt tcaaaaagca tagggcagaa
     3661 agaccagtcg aagttggcct atcatgtgac tgaggcgttg aagattacct tactattaag
     3721 tttcctttta ggatttttgt ccatcttcgc tgggaaagag atgataggac ttttggggac
     3781 ggagagggat gtagctgaga gtggtggact gtatctatct ttggtaggcg gatcgattgt
     3841 tctcttaggt ttaatgacta gtctaggagc cttgattcgt gcaacgcata atccacgtct
     3901 gcctctctat gttagttttt tatccaatgc cttgaatatt cttttttcaa gtctagctat
     3961 ttttgttctg gatatgggga tagctggtgt tgcttggggg acaattgtgt ctcgtttggt
     4021 tggtcttgtg attttgtggt cacaattaaa actgccttat gggaagccaa cttttggttt
     4081 agataaggaa ctgttgacct tggctttacc agcagctgga gagcgactta tgatgagggc
     4141 tggagatgta gtgatcattg ccttggtcgt ttcttttggg acggaggcag ttgctgggaa
     4201 tgcaatcgga gaagtcttga cccagtttaa ctatatgcct gcctttggcg tcgctacggc
     4261 aacggtcatg ctgttggccc gagcagttgg agaggatgat tggaaaagag ttgctagttt
     4321 gagtaaacaa accttttggc tttctctgtt cctcatgttg cccctgtcct ttagtatata
     4381 tgtcttgggt gtaccattaa ctcatctcta tacgactgat tctctagcgg tggaggctag
     4441 tgttctagtg acactgtttt cactacttgg gacccctatg acgacaggaa cagtcatcta
     4501 tacggcagtc tggcagggat taggaaatgc acgcctccct ttttatgcga caagtatagg
     4561 aatgtggtgt atccgcattg ggacaggata tctgatgggg attgtgcttg gttggggctt
     4621 gcctggtatt tgggcagggt ctctcttgga taatggtttt cgctggttat ttctacgcta
     4681 tcgttaccag cgctatatga gcttgaaagg ataggaaatg caaaaaacag cttttatttg
     4741 ggatttagac gggactttat tggactctta cgaagcgatt ttatcaggga ttgaggagac
     4801 ttttgctcag ttttctattc cttatgataa ggagaaggtg agagagttta tcttcaagta
     4861 ttcggtgcaa gatttgcttg tgcgggtggc agaagataga aatctggatg ttgaggtgct
     4921 aaatcaggtg cgtgcccaga gtctggctga gaagaatgct caggtagttt tgatgccagg
     4981 tgcgcgtgag gtgctagctt gggcagacga atcaggaatt cagcagttta tatatactca
     5041 taaggggaac aacgctttta ccattctcaa ggacttgggg gtggaatcct attttacaga
     5101 gattttaacc agtcagagtg gctttgtgcg gaagccaagt ccagaagcgg ctacctatct
     5161 gctagataag tatcagttga attctgataa tacttattat ataggggatc ggactctgga
     5221 tgtggaattt gcccagaata gtgggattca aagcatcaac tttttagagt ctacttatga
     5281 agggaatcac aggattcaag cgttagcaga tatttcccgt atttttgaga ctaagtgata
     5341 aaaagattgt gtcagttttg tgacagagac ctaacaaact atttcaagta acctagtttg
     5401 ttacaaggaa tagacagttc tgttaaatag gcccgagagg gctttttttc tacatttttt
     5461 gtgttatgat agacaggtac tcatttgaaa ggaatttgaa agaatgaaga aaagaatgtt
     5521 attagcgtca acagtagcct tgtcatttgc cccagtattg gcaactcaag cagaagaagt
     5581 tctttggact gcacgtagtg ttgagcaaat ccaaaacgat ttgactaaaa cggacaacaa
     5641 aacaagttat accgtacagt atggtgatac tttgagcacc attgcagaag ccttgggtgt
     5701 agatgtaaca gtgcttgcga atctgaacaa aatcactaat atggacttga ttttcccaga
     5761 aactgttttg acaacgactg tcaatgaagc agaagaagta acagaagttg aaatccaaac
     5821 acctcaagca gactctagtg aagaagtgac aactgcgaca gcagatttga ccactaatca
     5881 agtgaccgtt gatgatcaaa ctgttcaggt tgcagacctt tctcaaccaa ttgcagaagt
     5941 tacaaagaca gtgattgctt ctgaagaagt ggcaccatct acgggcactt ctgtcccaga
     6001 ggagcaaacg accgaaacaa ctcgcccagt tgaagaagca actcctcagg aaacgactcc
     6061 agctgagaag caggaaacac aagcaagccc tcaagctgca tcagcagtgg aagtaactac
     6121 aacaagttca gaagcaaaag aagtagcatc atcaaatgga gctacagcag cagtttctac
     6181 ttatcaacca gaagagacga aaataatttc aacaacttac gaggctccag ctgcgcccga
     6241 ttatgctgga cttgcagtag caaaatctga aaatgcaggt cttcaaccac aaacagctgc
     6301 ctttaaagaa gaaattgcta acttgtttgg cattacatcc tttagtggtt atcgtccagg
     6361 agacagtgga gatcacggaa aaggtttggc tatcgacttt atggtaccag aacgttcaga
     6421 attaggggat aagattgcgg aatatgctat tcaaaatatg gccagccgtg gcattagtta
     6481 catcatctgg aaacaacgtt tctatgctcc attcgatagc aaatatgggc cagctaacac
     6541 ttggaaccca atgccagacc gtggtagtgt gacagaaaat cactatgatc acgttcacgt
     6601 ttcaatgaat ggataaaccc gacttgataa catcattttg acgaatgaga tctagctttc
     6661 gtgatggaaa gcgattctcg ttcgtttttt ctttgtcata ctcttcgaaa atctcttcaa
     6721 accacgtcag ttttatctga aacttcaaag ctgtgctttg agcaacctgc gactagcttc
     6781 ctagtttgct ttttgatttt cattgagtat caatttgaat ggaaaatgga aagttatcat
     6841 cttgtaatga gttaagcaac attcttgcaa tctattttac tttatatcac aattaattag
     6901 tcaaatattg ataaatcaat aaaaagagag gggaagaaat gctagagatt caagatttac
     6961 tgtatcaact ccgcttgtct gagcaagcga gtacgcaatt gtttgaaaaa aggcttggga
     7021 ttagtttgac acggtatcag attttactgt ttttgctgga gcattctcct tgtaaccaaa
     7081 tggcggttca ggagcgtttg aaaattgatc aggctgcttt gacacggcat ttcaaaattt
     7141 tggaaacgga aggtttggtg gagcgtcatc gtaatcctga aaatcagcgg gaagtgttgg
     7201 tagaggctgc gaagtatgcc aaggagcagt tagtggtgaa tccccctctg caacatatca
     7261 gggttaagga agagatagaa agtatcttaa cagagtttga gagaacagaa ctcagccgtt
     7321 tattaaataa attggttttg ggtattgaaa atatagaaat ttaaggagaa atagatgtca
     7381 attattttaa caacgatcgt tgctttggag catttttaca ttttttattt ggaaagtatt
     7441 gccacgcaat cagatgcgac tagtcgtgta tttaatatgg aaaaggaaga attggctcat
     7501 ccgtcagtaa gttcattgtt caaaaatcaa ggaatttata aggctctgct aggagtcttt
     7561 ctcttgtatg tcatttattt ctcacagaat ttagaaattg tgactatttt tgtcttattt
     7621 gtgattggtg ctgcgactta cggctcttta acagcggata aaaaaattat tttgaaacaa
     7681 ggtggatcag ctattttggc cttgattagt attttactct ttaaatacac ttgaaggtcg
     7741 attctaatct cgctaatcct ttttaatcca gaataaggga aatatgttat acttgttttt
     7801 aagaaaaaag tctcattgaa ttggttttga ggagttagaa atgaaagtat tagtgacagg
     7861 ttttgagccc tttggagggg aaaagggcaa tccagctttg gaggccatta aaggtttacc
     7921 agctgaaatc catggtgctg aggtccgttg gctagaggtg ccgacagttt ttcacaaatc
     7981 tgctcaagta ttggaagaag agatgaatcg ttatcaacct gactttgtcc tttgtattgg
     8041 gcaagctggt ggaagaacta gtttgacacc tgaacgagtg accattaatc aagacgatgc
     8101 atgcatttct gataacgaag ataatcaacc gattgaccgt cccattcgcc cagatggtgc
     8161 ttcggcctac tttagtagtt tgccgattaa agcgatggtt caagctataa aaaaagaggg
     8221 cttaccggcc tctgtttcca atacggcagg gacttttgtc tgcagccatt tgatgtatca
     8281 ggctctctat ttggtagaaa agaaatctcc atatgttaag gcaggtttta tgcatattcc
     8341 ttatatgatg gaacaggtgg tgaacagacc gactactcca gctatgagtt tagtggatat
     8401 tcggcgaggg atagaagcag caatcggcgc tataatagaa catggagatc aggaactcaa
     8461 gttggtaggc ggagaaactc attgatagaa aaaagcttga ggggaaaaac cttcaagctt
     8521 ttggacgttt tcgggccaat actgctcggt aaaacataat tttagtgcat tggatataag
     8581 gtaggagtga aaaactagca atgccaaagg taatccaatt gaggaagtac caaggaagaa
     8641 gctgtaaatc taggacaaag tgctggaact tgtagccctt cataaaggaa cggctagttt
     8701 ttaggattcg tcttggtggg acctgtccta ggtctagact ataacagaga agaaattcca
     8761 cctgtgaata ggcataatac tgtggaatat agaggatatt tcctacaatg atcaagatga
     8821 gacttgcaag aaagtagagt ccaaagacca tgaggaaacg ctcggtttca actgatgaga
     8881 gatctagatt tggaaactca ggatgtaggg tgacgaattt tttggctaaa aagctactat
     8941 aaaagaggag gtaaatccca agtaaattag ggatactcca taaaaagaga tagaaacgtt
     9001 tgagaagtag ggtcaaaaag gtttgagaaa agcgctcctc atcaaagaga gctaggctgt
     9061 tttttacaga tggctccgtt ttagaatctt tcatgagtgt cagtgttgca tagacggaac
     9121 tggtcaaaag aatagtcccg ataaaggaga ctagtagagg aaagaggtag gtttgaagta
     9181 tttggccaag tatgctgaaa aatggctgtt ctaaaacagt cccgtggatc cgagataagg
     9241 gattaagaaa accagataag atgaccagca tactgggaag gatatagagg agaaagagac
     9301 ggggggtgtc agcctgaaaa tgttttgact cctgacgaat tgtttttaaa tcaatttttg
     9361 gatagttcat tctcttatta taccatagtt cttatacata gttcgtgaca gttcctactt
     9421 tttttgataa aatcatacag tgtgtccttg ggcacactgt atgaactggg actgtctttc
     9481 ccagcttcgg aggtaaaaaa tgtcagattc accaatcaaa tatcgtttga ttaagaaaga
     9541 aaaacacaca ggagctcgtc tgggagaaat catcactccc cacggtacct ttccgacacc
     9601 tatgtttatg ccagttggga cacaagccac tgtcaaaact cagtcacctg aagaattgaa
     9661 ggagatgggt tcgggaatta tcctatcaaa cacctatcat ctctggcttc gccctggaga
     9721 tgaactcatt gcacgcgctg gtggtctcca caagttcatg aattgggacc agcctatctt
     9781 gacagatagt ggtggttttc aggtttattc tttagcagat agccgtaata tcacagaaga
     9841 aggagtaacc tttaaaaatc atctaaatgg ttctaagatg ttcctatccc cagaaaaagc
     9901 catctctatt cagaataatc tgggttcaga catcatgatg tcctttgatg aatgtcctca
     9961 gttttatcaa ccttatgact acgttaagaa atcgatcgag cgtaccagcc gttgggctga
    10021 gcgtggtttg aaggctcacc gtcgtccaca tgaccaaggt ttgtttggaa ttgtgcaagg
    10081 tgcaggattt gaagaccttc gccgccaatc agctcatgat cttgtcagca tggatttctc
    10141 aggctactct atcggtggtt tggcagtggg agaaacccat gaagagatga atgcggtctt
    10201 ggactttaca actcaactgc tacctgaaaa taaacctcgt tatctgatgg gtgtgggagc
    10261 gccagatagc ttgatcgatg gggtcattcg tggggtggat atgtttgact gtgtcttacc
    10321 gactcgaatt gctcgtaacg ggacttgtat gaccagtcaa ggacgtttgg ttgtgaaaaa
    10381 tgcccagttt gctgaggact ttacgccact ggatcctgag tgtgactgct acacatgtaa
    10441 taactataca cgcgcttacc ttcgtcacct gctcaaggct gatgaaacct ttggtatccg
    10501 cttgactagc taccacaatc tttacttctt gcttaacctg atgaagcaag tgcgacaagc
    10561 catcatggat gacaatctct tggaattccg tgagtatttt gtggaaaaat atggctataa
    10621 taagtcagga cgtaatttct aaaatggaat tgatataaaa aaatcctaag ttttctctta
    10681 ggatttttct tctttttttg atagaataaa gtgtacaatg aaaggaagaa taaactcgta
    10741 tgcgcattaa atggttttcc ttgattagga ttataggttt acttttggta ctcttgtatc
    10801 acttctttca gacgatcttt cctggaggat ttttcggggt agatgtcttt ttcacatttt
    10861 caggtttcct gattacagct ctactcattg aagaattttc taagaacaat gagattgatt
    10921 tgataggatt ttttagaaga cgcttttatc ggattgtgcc acctgtggtt ttgatggtct
    10981 tggtgaccat gccttttact ttcttggttc gccaagacta tgttgctgga attggtggcc
    11041 agattgcggg cgtcttaggc tttatgacca acttctatga actcctaaca ggtgggagtt
    11101 atgaatctca gttcattcct catttgtttg ttcataattg gagtttggca gttgaggttc
    11161 actactatat tctttgggga ttggcagttt ggttcttatc caaacaagct aaatcaaatg
    11221 gtcagttgaa ggggatggtc tttctcttat ctgctgctgc cttcttgatc agtttcttct
    11281 ccatgtttat tggtagtttt ctagtgacct cttattcctc tgtttatttc tccagtttaa
    11341 ctcatgtcta tccattcttt ttgggaagta tgttagcaac tattgtaggt gttcgtcaga
    11401 cgacttccct cgtcaagcag ttggataaaa tctgggattt acgaaagact ttggtagttt
    11461 ttggaggagg ctttggtttc ctagttcttt tgactttctt tgtcaaattc acttatcttt
    11521 ttgcctatct tatcggcttc ttgcttgcca gtcttgcagc tcttgccatg attctggcgg
    11581 cgcgtgtctt acatgaaaag acacatcata tacaggagcc gaagattatc agctttttag
    11641 cggatactag ctatgcggtt tatcttttcc attggccttt ctatatcatt ttctcacagt
    11701 tgacatcaaa tcttcttgct gtattactga ctctgatttg ttcttatggc tttgccagtc
    11761 tgtcattcta tgtattggaa ccttggattg caggcaagaa cacacctatt ttacaaactc
    11821 ttcgtcccct gccttatatt cacgcaattc ttgtagcagg tacaggaatc ttgaccatca
    11881 ttgtctgcac ggtgaccttg ttggcaccac aagtgggagc gtttgagaca gacttgactg
    11941 tcaatggctt gaagcaagct gcaacaaata ttggccagac caaggtgatg gcagaacggg
    12001 cagatgcaaa cagtttggga attgctgatg gcactatgtt aattggtgac tcagtggctt
    12061 taagggcaaa tacagcacta cagacagctc ttcctggagc acagattaac gcgcaggtca
    12121 gcgtaacaac caagaccgca aatgaaatca tgctaaataa tagccagaat aaatttttac
    12181 ctaagacggt ggtcattgcg actggggtaa ataatcctga gaattacaag gatgactggg
    12241 acagtatcgt gaaaaatctt cctaagggac accatatgat tttggtgact ccttatgagg
    12301 gagataagac aaaagagacc tatgccatcg ttgagaaggc tgctgcctat atgagagaat
    12361 tggcagagaa gacaccttac attacgatag cagattggaa tcaagttgcg aaagagcatc
    12421 cagaaatttg ggctggaaca gaccaggttc atttcgggag tgagagtagc actatcgaag
    12481 caggagcaaa attgtatgca gatacgattg ccacagcttt gcagacagct caagacaagc
    12541 cggttaaatc aaaataactt gtattaaaaa agagaagagt tggagaaatc cagctctttt
    12601 aaaatatctc caaaaaatag gtctatacca tttacaaata aaaaagaaag gtttataatg
    12661 taattgacat aataaattgt agaatcaatc ttttaaggag gttaacatta tgcctaacta
    12721 tattaaagcg gatcagtttt tctacccaca cggagttcgt cgaggtggtt acttggaact
    12781 tgtggacggc aagtttggga aacatgtaga gcagattcct gaaggggctg aggtgattga
    12841 ctatacaggt tatagcattg ccccaggtct tgtggatact catattcatg gatatgcagg
    12901 tgtagatgtg atggacaaca acattgaagg tacattgcat actatgagtg aaggacttct
    12961 tagtaccggt gttaccagtt tcttacccac aactttaaca gccacttatg agcaattgct
    13021 tgcagtcact gaaaatcttg gaaaccatta taaagaagca acaggtgcta agattcgtgg
    13081 gatttattat gaaggtccat atttcacaga aacttttaag ggggcacaaa atccaactta
    13141 tatgagagac ccgggtgttg aggagtttca ttcttggcaa aaagcggcaa atggcttgct
    13201 taataaaatt gcccttgcac cagaacgtga tggggtggaa gactttgttc gtacagttac
    13261 gggcgaaggt gtgacggttg ctcttggaca ttcaaacgcg acttttgatg aagccaaaaa
    13321 agcagtcgat gctggagcga gtgtttgggt gcatgcctac aatggaatgc gtgggttgac
    13381 tcaccgtgaa ttgggtatgg ttggagccat gtaccaattg ccacatacct atgcagagtt
    13441 gatctgtgat ggtcaccacg tagatccaaa ggcttgcgaa attcttatca aacaaaaagg
    13501 aacagaaaac atcgctctta tcacagactg tatgacagct gggggattgg aagacggaga
    13561 ttatatgttg ggagaattcc cagttgtcgt tgcaaatgga actgcacgcc tcaaatcgac
    13621 aggtaacttg gcaggttcta tcctcaaact caaagatggt ttgaagaatg tggtcgaatg
    13681 gggaattgcg aatccgcatg aagcagtcat gatggccagc ttcaacccag ctaaatccgt
    13741 tcacatcgat gacgtctgtg gccaaatccg tgaaggctac gacgctgact tcatcgtatt
    13801 agataaagat ttggaattgg tagcaaccta tctagatggc gtaaaacgtt atcaagcata
    13861 agagagaagg cagaagttag agactagctt ctgctttttt atacagggta ctttactggt
    13921 aaataaaaag ttaaaaaaat cacaaaaaaa gcttgaagaa acaaagaaaa aggcttacaa
    13981 ttgaactata aatattacaa ataaaaaaac ggaggagtgc tttatgaaag cctatactta
    14041 tgttaaacca ggacttgctt cttttgttga tgtagacaaa ccagttattc gcaagccaac
    14101 agacgctatt gtgcgtattg taaaaaccac tatttgtgga acagacctcc atattatcaa
    14161 aggggatgtt cctacttgcc aaagtggtac cattcttggc cacgaaggga ttgggattgt
    14221 tgaagaagtt ggggaaggag tttccaactt caaaaaaggc gacaaggtct tgatttcttg
    14281 cgtctgtgcc tgtggtaaat gctactactg taaaaaagga atttatgccc actgtgaaga
    14341 cgaagggggc tggattttcg gtcacttgat tgatggtatg caggctgaat atctacgtgt
    14401 ccctcatgca gataatactc tttaccatac tccagaagac ttgtcagatg aagctttggt
    14461 tatgctgtca gacattctgc ctactggata tgaaattggt gtcttaaaag ggaaagtaga
    14521 acctggttgc agcgtagcca ttattggttc aggtccagtt ggattggctg ctcttttaac
    14581 agcccaattc tattcaccag ctaaattgat tatggtagac ctagacgata accgcttgga
    14641 aactgcccta tcattcggtg cgactcataa ggttaattct tcagacccta aaaaagccat
    14701 taaagaaatt tatgatttga cagatggtcg tggtgtggat gtcgctatcg aagctgtagg
    14761 gattcctgaa acatttgatt tctgtcaaaa gattatcggt gtagacggaa cggttgccaa
    14821 ctgtggtgtg catggtaaac cagttgaatt cgatttagat aaactttgga ttcgcaacat
    14881 caatgtaaca actggtttgg tatctacaaa tacgactcca caattgttga aagcacttga
    14941 aagtcataag attgaaccgg aaaaattggt aactcactat ttcaaactca gtgaaattga
    15001 aaaagcctac gaagtcttca gtaaggcagc agaccaccat gccattaagg tcattatcga
    15061 aaacgatatc tcagaagcct aagtagtaaa aatatttttg tacataagta aatagaaatt
    15121 cagtcatcca tcagatggtt ggatttttta tcaaaaaatt aagaaatgag catatttctt
    15181 tccttgtctg gtggaattgg ttataatata cggtacaaag gaatgaatga atatgtatcg
    15241 tgttatagaa atgtacggag attttgaacc gtggtggttc ttagaaggtt gggaagaaga
    15301 tattgtagca agtagaaaat ttgaccagta ttatgatgct ctcaaatact acaaaacttg
    15361 ctggtttaga ttggaacaag aatcgcctct ttataaaagt agaagcgact tgatgaccat
    15421 tttttgggac ccggaagacc aacgctggtg tgatgaatgt gatgagtatt tacaacaata
    15481 ccattctttg gctcttttgc aggatgagca ggttatccca gacgaaaaac tacgctcagg
    15541 ctatgaaaaa caaaccagtc aggaaaggaa tcgttcttgc cgtatgaaat taaaatagag
    15601 aaaagtaact ttttggagtt gcttttttta tttttctaac gctttgcgaa tagtataggt
    15661 gaggaggtaa gtatggttca agaaattgca caagaaatca ttcgttcggc tcggaaaaaa
    15721 ggggcgcaag acatttattt tgtccccaag ttagatgcct atgagcttca tatgagggta
    15781 ggagacgagc gctgtaaaat tggtagctat gattttgaaa agtttgcagc cgttatcagt
    15841 cactttaagt ttgtggcggg tatgaatgtg ggagaaaaaa gacgtagtca actgggttcc
    15901 tgtgattatg cctatgacca gaagatggcg tctctacgtt tatctactgt aggcgattat
    15961 cgggggcatg agagtttggt tatccgtttg ttgcacgatg aggagcagga cttgcatttt
    16021 tggtttcagg atattgaaga attaggcaag cagtacaggc aacggggact ctatcttttt
    16081 gctggtccgg ttgggagtgg taagacgacc ttgatgcatg aattgtccaa gtcactcttt
    16141 aaaggacagc aagttatgtc catcgaagat cctgtcgaaa tcaagcagga cgacatgctt
    16201 cagttgcagt tgaacgaagc aatcggccta acctatgaaa atctaatcaa actttccttg
    16261 cgtcatcgac cagatctctt gattatcgga gaaattcgtg acagcgagac ggcgcgtgca
    16321 gtggtcagag ctagtttgac aggtgcgaca gtcttttcaa ccattcacgc caagagtatc
    16381 cgaggtgttt atgagcgtct gctggagttg ggtgtgagtg aagaagaatt ggcagttgtt
    16441 ctgcaaggag tctgctacca gagattaatc gggggaggag gaatcgttga ctttgcaagc
    16501 agagattatc aagaacacca agcagccaag tggaatgagc aaattgacca gcttcttaaa
    16561 gatggacata tcacaagtct tcaggctgag acggaaaaaa ttagctacag ctaagcaaaa
    16621 aaatatcatc accctattta acaatctctt ttctagcggt tttcatctgg tggagaccat
    16681 ctccttttta gataggagtg ctttgttgga caagcagtgt gtgacccaga tgcgtgcggg
    16741 cttgtctcag gggaaatcat tctcagaaat gatggaaagt ttgggatgtt caagtgctat
    16801 tgtcactcag ttatccctag ctgaagtcca tggcaatctc cacctgagtt tgggaaagat
    16861 agaagagtat ctagacaatc tggccaaggt caagaaaaaa ttaattgaag tagcgaccta
    16921 tcctttgatt ttgctgtttt ttcttctctt aattatgctg gggctacgga attacctgct
    16981 cccacaactg gatagtagca atattgccac ccgaattatc ggtaatctgc cacaaatttt
    17041 tctaggcatg gtagggcttg tttccgtgct tgccctttta gcactaactt tttataaaag
    17101 aagttctaaa atgagtgtct tttctatctt agcacgcctt ccctttattg gaatctttgt
    17161 gcagacctac ttgacagcct attatgcacg tgaatggggg aatatgattt cacagggaat
    17221 ggagctgacg cagatttttc aaatgatgca ggaacaaggt tcccagctct ttaaagaaat
    17281 cggtcaagat ctggctcaaa ccctgaaaaa tggccgtgaa ttttctcaga cgataggaac
    17341 ctatcctttc tttaggaagg aattgagtct catcatagag tatggggaag ttaagtccaa
    17401 gctgggtagt gagttggaaa tctatgctga aaaaacttgg gaagcctttt ttacccgagt
    17461 caaccgcacc atgaatttgg tgcagccact ggtttttatc tttgtggcac tgattatcgt
    17521 tttactttat gcggcaatgc tcatgcccat gtatcaaaat atggaggtaa atttttaaaa
    17581 tgaaaaaaat gatgacattc ttgaaaaaag ctaaggttaa agcttttaca ttggtggaga
    17641 tgttggtggt cttgctgatt atcagcgtgc ttttcttgct ctttgtacct aatctgacca
    17701 agcaaaaaga ggcagtcaat gacaaaggaa aagcagctgt tgttaaggtg gtggaaagcc
    17761 aggcagaact ttatagcttg gaaaagaatg aagatgctag cctaagcaag ttacaagcag
    17821 atgggcgaat cacggaagaa caggctaaag cttataaaga ataccatgat aaaaatggag
    17881 tagcaaatcg taaagtcaat gattaaggcc tttaccatgc tggaaagtct cttggctttg
    17941 agtcttgtga gtatccttgc cttgggcttg tccggctctg ttcagtccac ttttgcggca
    18001 gtagaggaac agattttctt tatggagttt gaagaactct atcgggaaac ccaaaaacgc
    18061 agtgtagcca gtcagcaaaa gactagtctg aacttagatg ggcagacgct tagcaatggc
    18121 agtcaaaagt tgccagtccc taaaggaatt caggccccat caggtcaaag tattacattt
    18181 gaccgtgctg ggggcaattc gtccctggct aaggttgaat ttcagaccag taaaggagcg
    18241 attcgctatc aattatatct aggaaatgga aaaattaaac gcattaagga aacaaaaaat
    18301 tagggcagtg attttactgg aagcagtagt cgctctagct atctttgcca gcattgcgac
    18361 cctccttttg ggacaaattc aaaaaaatag gcaagaggaa gcaaaaatct tgcaaaagga
    18421 agaagtcttg agggtagcta agatggccct gcagacgggg caaaatcagg taagcatcaa
    18481 cggagttgag attcaggtat tttctagtga aaaaggattg gaggtctacc atggttcaga
    18541 acagttgttg gcaatcaaag agccataagg tcaaggcttt taccttgtta gaatccctgc
    18601 ttgccctcat tgtcatcagt gggggattac tcctttttca agctatgagt cagctcctca
    18661 tttcagaagt tcgctaccag caacaaagcg agcaaaagga gtggctcttg tttgtggacc
    18721 aacttgaggt agaattagac cgttcgcagt tcgaaaaagt ggaaggcaat cgtttctata
    18781 tgaagcaaga tggcaaggac atcgccatcg gtaagtcaaa gtcagacgat tttcgtaaaa
    18841 ccgatgctag tggacggggg tatcagccta tggtttatgg cctcaaatca gctcagatta
    18901 cagaggacaa tcaactggtt cattttcgtt tccagtttca aaaaggctta gaaagggagt
    18961 tcatctatcg tgtggaaaaa gaagaaagtt aaggcaggtg ttctcctcta tgcagtcacc
    19021 atggcagcta tctttagtct tttgttgcaa ttttacttga accgacaagt cgcccactat
    19081 caagactatg ctttgaataa agaaaaattg gttgcttttg ccatggctaa acgaaccaag
    19141 gataaagccg agcaagaaag tggggaacag gtctttaatc taggtcaggt aagctatcaa
    19201 aacaagaaaa caagcttggt gacgactgtt cgtacggata agagtcaata tgagtttctg
    19261 tttccttcag tcaaaatcaa agaagagaaa agagataaaa aggaagaggt agcgactgat
    19321 tcaagcgaaa aagcggagaa gaaaaaatca gaagagaagc ctgaaaagaa agagaattcc
    19381 tagtcaattc aactataatg cgttgaatcc aaaatagtcc actgtagttt ctagaaaatt
    19441 gctggaaatg gatgttaagc tccaattcat ttgtttatat cttatttcag tttactatac
    19501 tttgtgctaa actaaagata tgaaacatga ttttaaccac aaagcagaaa ctttcgattc
    19561 ccctaaaaaa tcttcctcgc aaacttggta tgtcaagcag ccgagaaaca gattgatctt
    19621 ctatcagaca aagaaatttt agatttcggt ggtggcacgg atctattagc cttgccccta
    19681 gcccctagcc aagcaggcta agtcagtcac tcttgtagac atttctgaga aaatgttgga
    19741 gcaagctcgt ttgaaagtgg agcagcaagc aatcaagaat atccagtttt tggagcaaga
    19801 tttaccgaaa aatcccttgg agaaagagtt tgattgcctt gctgttagtc gggttcttca
    19861 tcatatgcct gatttggatg cggctctctc actgtttcat caacatttga aggaagatgg
    19921 gaaactcatc attgctgatt ttaccaagac agaagctaat catcatggat ttgatttagc
    19981 tgaactggaa aacaagctaa ttgagcatgg tttttcatct gtgcatagtc agattctcta
    20041 tagcgctgaa gacctgtttc aaggaaatca ctcagaattc tttttaacag tagcccaaaa
    20101 atcactcgcc tagtcaggga gtgatttttc tataaggatg gaaaaaagaa gggaaatttg
    20161 gtaagatagt aatatggatt ttgaaaaaat tgaacaagcc tatacctatt tactagagaa
    20221 tgtccaagtc atccaaagtg atttggcgac caacttttat gacgccttgg tggagcaaaa
    20281 cagcatctat ctggatggtg aaactgagct aaaccaggtc aaagacaaca atcaggccct
    20341 taagcgttta gcactacgca aagaagaatg gctcaagacc taccagtttc tcttgatgaa
    20401 ggctggggaa acagaaccct tgcaggccaa tcaccagttt acaccagatg ccattgcttt
    20461 gcttttggtg tttattgtgg aagagttgtt taaagaggag gaaattacta tcctcgaaat
    20521 gggttctggg atgggaattc taggcgctac tttcttgacc tcgcttgata aaaaggtgga
    20581 ttacttggga atggaagtgg atgatttact gattgatctg gcagctagca tggcagatgt
    20641 aattggtttg caggctggct ttgtccaagg agatgccgtt cgtccacaaa tgctcaaaga
    20701 aagcgatgtg gtcatcagtg acttgcctgt cggctattat cctgatgatg ccgttgcgtc
    20761 gcgtcatcaa gttgcttcta gccaagaaca tacttacgcc catcacttgc tcatggaaca
    20821 agggtttaag tacctcaagt cagatggata tgctattttt ctagctccga gtgatttgtt
    20881 gaccagtcct caaagtgatt tgttgaaagt ctggttgaaa gaggaggcaa gtctggttgc
    20941 tatgattagt ttacctgaaa atctctttgc taatgccaaa caatctaaga ctatttttat
    21001 cttacagaag aaaaatgaaa tagcagtaga gccttttgtt tatccacttg ctagcttgca
    21061 agatgcaagt gttttaatga aatttaaaga aaattttcaa aaatggactc aaggtactga
    21121 aatataaaat agattttgtt ataatagttg aaaacgctta aaaaggggta tcatgttatg
    21181 acaaaaacaa ttgcaatcaa tgcaggaagt tcaagtttga aatggcaatt atacttaatg
    21241 ccagaggaaa aagtgttagc caaaggtttg attgaacgta tcggtttgaa agattcaatt
    21301 tcaactgtaa aatttgacgg ccgttctgaa caacaaattt tggatatcga aaatcataca
    21361 caagccgtta aaattttatt ggatgacttg attcgtttcg atattatcaa ggcttatgac
    21421 gagattacag gtgttggaca tcgtgttgtt gctggtggag aatatttcaa agaatcaaca
    21481 gttgttgagg gagatgtttt agaaaaagtt gaagagttga gtttgttggc tcctctacac
    21541 aacccggcca atgcagcagg tgttcgtgcc ttcaaggaat tgttgccaga cattaccagt
    21601 gtagttgttt ttgatacttc cttccacaca agtatgccag agaaagctta tcgctaccct
    21661 ctaccaacaa aatattacac agaaaacaag gttcgtaaat acggtgctca tggtacaagt
    21721 caccagtttg tagcaggaga agctgcaaaa ctcttgggac gtccattaga agacttgaag
    21781 ttaattacct gtcatattgg taacggaggc tcaattacag ctgtgaaagc cggcaaatct
    21841 gtagacactt ctatggggtt cactcctctt ggtggtatta tgatgggaac gcgtacaggg
    21901 gatattgatc cagctatcat tccttattta atgcaatata cagaggattt taacacacca
    21961 gaagatatca gtcgtgttct taaccgtgaa tcaggtcttt tgggagtttc tgctaattct
    22021 agcgatatgc gcgatataga agcagctgta gcagaaggga atcacgaggc tagcttggct
    22081 tatgaaatgt atgttgaccg tatccaaaaa catatcggtc agtaccttgc agtgctaaat
    22141 ggagcagatg ccattgtttt cacagcaggt gtcggtgaaa atgcagagag tttccgtcgt
    22201 gatgtaatct cagggatttc gtggtttggt tgtgatgttg atgatgaaaa gaatgtcttt
    22261 ggcgttacag gagacatctc aacagaggca gctaaaatcc gtgtcttggt tattccaaca
    22321 gatgaagaat tagtcattgc ccgtgacgtt gaacgcttga aaaaataagt gaaactaaaa
    22381 aaatattcaa tacaaggagt tgggaaagtt atttttccag cttctttttc tgatgaaatt
    22441 gtccaaaacc ttgctatgat tggctttttt gaaaaatatg gtataatagt agtaatttaa
    22501 tagatggagt tgagttttga agaaaaactt tcgtgtaaaa agagagaaag attttaaggc
    22561 gattttcaag gaggggacaa gttttgctaa tcgcaaattt gtggtctacc aattagaaaa
    22621 ccagaaaaac cattttcgag taggtctatc agttagcaaa aaactgggga atgccgtcac
    22681 tagaaatcaa attaagcgac ggattcggca tattatccag aatgcaaaag ggagtctggt
    22741 agaagatgtc gactttgttg tcattgctcg aaaaggagtc gaaaccttgg gatacgcaga
    22801 gatggagaaa aatctactcc atgtattaaa attatcaaag atttaccggg aaggaaatgg
    22861 gagtgaaaaa gaaactaaag ttgactagtt tgctaggact gtctctgtta atcatgacag
    22921 cctgtgcgac taatggggta actagcgata ttacagccga atcggctgat ttttggagta
    22981 aattggttta cttctttgcg gaaatcattc gctttttatc gtttgatatt agtatcggag
    23041 tggggattat tctctttacg gtcttgattc gtacagtcct cttgccagtc tttcaggtgc
    23101 aaatggtggc ttctaggaaa atgcaggaag ctcagccacg cattaaggcg cttcgagaac
    23161 aatatccagg tcgagatatg gaaagcagaa ccaaactaga gcaggaaatg cgtaaagtat
    23221 ttaaagaaat gggtgtcaga cagtcagact ctctttggcc gattttgatt cagatgccgg
    23281 ttattttggc cctgttccaa gccctatcaa gagttgactt tttaaagaca ggtcatttct
    23341 tatggattaa ccttggtagt gtggatacaa cccttgttct tccgatttta gcagcagtat
    23401 tcaccttttt aagtacttgg ttgtccaaca aagctttgtc tgagcgaaat ggcgctacga
    23461 ctgcgatgat gtatgggatt ccagtcttga tttttatctt tgcagtttat gcgccaggtg
    23521 gagtcgccct atactggaca gtgtctaatg cttatcaagt cttgcaaacc tatttcttga
    23581 ataatccatt caagattatc gcagagcgcg aggccgtagt acaggcacaa aaagatttgg
    23641 aaaatagaaa aagaaaagcc aagaaaaagg ctcagaaaac gaaataaata aggaggaatc
    23701 tggtaatggt agtatttaca ggttcaactg ttgaagaagc aatccagaaa ggattgaaag
    23761 aattagatat tccaagaatg aaggctcata tcaaagtcat ttctagggag aaaaaaggct
    23821 ttcttggtct atttggtaaa aaaccagccc aagtggatat tgaagcgatt agtgaaacga
    23881 ctgttgtcaa agcaaatcaa caggtagtaa aaggcgttcc gaaaaaaatc aatgatttga
    23941 acgagcctgt gaagacggtt agtgaagaaa ccgttgacct tggtcatgtg gttaatgcta
    24001 ttaaaaaaat agaggaagaa ggtcaaggta tttctgatga agtcaaggct gaaatcttaa
    24061 aacatgaaag acatgccagc actatcttag aagaaactgg tcacattgag attttaaatg
    24121 aacttcaaat cgaggaagcg atgagggaag aagcaggcgc tgatgacctt gaaactgagc
    24181 aagatcaaac tgaaaatcaa gacttgaaag agatgggctt gaaggtcgag caaagttatg
    24241 atattgccca ggtggctacg gatgtgactg cctatgttca agcgattgtg gatgacatgg
    24301 atgttgaagc tacactttca aatgattata accgtcgtag catcaatcta caaattgaca
    24361 ccaacgaacc aggtcgtatt atcggctacc atggtaaagt cttgaaggcc ttgcaactgt
    24421 tggctcaaaa ttatctttac aaccgctatt ccaaaacctt ctacgttaca atcaatgtca
    24481 atgattatgt cgaacaccgt gcagaagtct tgcagaccta tgcgcaaaaa ttggcgaatc
    24541 gtgttttgga agaaggtcgc agtcataaaa cagatccaat gtcaaatagc gaacgcaaga
    24601 ttatccatcg tattatttca cgtatggatg gcgtgactag ttactctgaa ggtgatgagc
    24661 caaatcgcta tgttgttgta gatacagaat aagtaaaatc agggttgacc tgattttttg
    24721 ctagttagag gaggttaaac tgatgttgaa taagataaga gactatctag acttttctgg
    24781 tttgcagtac cgtagtcctg ataaagcggg agcagagcga gagaagatgc tggcgttccg
    24841 ccacaaagga caagaggccc gaaaggcttt tacagaactg gccaaagcct ttcaagcaag
    24901 ccatccagaa tggcaactcc aacagactag tcagtggatg aatcaggccc agtgtttgag
    24961 accacatttt tgggtttatc tacagagaga cggacaagtg acagaaccta tgatggcctt
    25021 acgtttgtat gggacatcta ctgactttgg aatttctttg gaagtcagtt tcatcgaacg
    25081 taagaaggat gagcaaacac tgggcaagca gaccaaagtt ttagacattc caaccgttaa
    25141 agggatttat tatctaacct actctaatgg tcaaagtcaa cggtgggagg cgaatgaaga
    25201 aaagcgtcgt actttacgcg agaaggtgag aagtcaagaa gttcgaaaag ttttagtgaa
    25261 ggtagatgtt cctatgacag aaaattcgtc tgaagaagaa atcgtagaag gcttattgaa
    25321 gtcttattct aaaattcttc cctattatct agctacgaga aaataagata atttgtaaaa
    25381 catcataaat catcataaat catacagtcc aagagtgaac agtccgctgt gtaattcttg
    25441 gtctttttgt ttgcgctttc gcattatata ataaacttac aaaaacaatt caaaaggaga
    25501 acaattatgg aagtcgtttc aagtgttcta aattggtttt ctagcaatat tttgcagaat
    25561 cccgcatttt tcgtaggttt attggtgttg ataggatatg cacttttgaa aaaacctgcc
    25621 catgacgttt tttcagggtt tgttaaagca acagtagggt atatgttgct taacgtgggt
    25681 gctggtggtt tggttacaac ctttcgtcca atcttagcag ctcttaacta caaattccaa
    25741 attggtgcag cggttatcga cccttacttt ggacttgctg cagcaaacaa caaaattgca
    25801 gcagagtttc cagattttgt tggaactgca actacagctc tattgattgg ttttggaata
    25861 aatatcttgc tcgtagctct tcgaaagatt acgaaggtaa gaaccctctt tattactggt
    25921 cacatcatgg tacaacaagc tgcaacagta tctcttatgg ttctattctt agtaccacaa
    25981 ttgcgcaatg cttacggtac agcagcgatt ggtatcatct gtggacttta ctgggcagtt
    26041 agttcaaata tgactgttga ggcaactcaa cgcttgactg gtggtggcgg atttgcgatt
    26101 ggtcaccaac agcaatttgc aatctggttt gtagataaag tagcaggacg ctttggtaag
    26161 aaagaagaaa gtttagacaa tcttaaatta cctaagttcc tctcaatctt ccacgataca
    26221 gttgttgcat ctgctacctt gatgctcgta ttcttcggag ccattctttt aatcttgggt
    26281 ccagacatta tgtctaataa agaagtcatc acttcaggaa ctctattcaa tcctgctaaa
    26341 caagatttct ttatgtacat tatccaaaca gcctttacct tctcagttta cttgttcgtt
    26401 ttgatgcaag gtgtccgaat gttcgtatct gagttgacaa acgccttcca aggtatttca
    26461 aacaaattgt tgccaggttc attcccagcg gttgacgttg cagcttctta tggatttggt
    26521 tctccaaatg ctgtcttgtc aggatttacc tttggtttga ttggtcaatt gattacaatt
    26581 gtcttgctca tcgtctttaa aaatccgatt cttattatta caggatttgt accagtgttc
    26641 tttgacaatg cagccattgc ggtctacgct gataaacgcg gcggatggaa agcggctgtt
    26701 atcctttcct ttatatcagg tgtccttcaa gttgctctag gagctctttg tgtggccctt
    26761 ctcgatttgg catcttatgg tggctaccat ggaaatatcg actttgaatt cccatggctt
    26821 ggatttggat atatcttcaa ataccttggt attgttggtt atgtacttgt gtgtctcttc
    26881 ttgcttgtta ttcctcaact tcaatttgcc aaagcaaaag atagagagaa atattacaac
    26941 ggtgaagttc aagaagaagc ttagtatcta gaaaaggaga aataaaatgg ttaaagtatt
    27001 agcagcgtgc ggaaatggaa tgggttcatc aatggttatc aagatgaagg ttgaaaatgc
    27061 tctccgtaag cttaatcaaa cagattttac agtcaattca tgcagtgtcg gtgaagctaa
    27121 aggtttagca gtaggatatg acatcgtaat cgcttctctt catttgattc aagaattgga
    27181 agggcgaact aatgggaagt taattgggct tgataacttg atggatgata aagaaatcac
    27241 cgaaaaactc agtcaagcac tacagtaaaa ggttggaggg gctggacaga aactgagagt
    27301 tatcgtttct gtccttctcc ctctttaaat aaaggaggca gatatgaatt taaaacaagc
    27361 tttaattgac aatgactcga tccgactagg tttagaggct aacaattgga aagaagcagt
    27421 caaggtagca gtagatccct taattgaaag tggggcaatt ttgccagagt attacgatgc
    27481 tatcattgaa tcgactgaag agtatgggcc ttactatatc ttgatgccag gtatggctat
    27541 gccccacgct agacctgaag ctggtgtgca aagtgatgcc ttttcattga ttaccttaca
    27601 aaatcctgtt gtattttcag atgggaaaga ggtatctgtt ttgttggcac tagcagcaac
    27661 aagttcaaaa attcacacaa gtgtagccat tccacaaatt attgccctgt ttgaattaga
    27721 agattctatt gcacgtttac aggcttgcca gactaaagaa gatgtcttgg ctatgattga
    27781 agaatctaag gatagccctt atctcgaagg attggatttg gaaagttaga aagaggaata
    27841 aagaaatgac aaaaagaata cctaatttac aagttgcatt agaccattca gacttgcaag
    27901 gagcgattaa agcagctgtt tctgttggtc aggaagtaga tattatcgaa gctggaactg
    27961 tttgcttgct tcaagttgga agtgaactgg ctgaagtctt gcgtagcctt ttcccagata
    28021 agattattgt ggcagacaca aaatgtgctg atgctggtgg aacagttgct aaaaataatg
    28081 cggttcgtgg agcagactgg atgacttgta tctgttgtgc aaccatccct actatggaag
    28141 cagctctaaa ggctatcaag actgaacgag gagaacgagg cgaaatccag atcgagcttt
    28201 atggcgattg gacttttgaa caagctcagc tttggctaga tgcaggtatt tcacaagcta
    28261 tttatcacca atctcgtgat gctcttcttg ctggtgaaac ttggggtgaa aaagacctta
    28321 ataaggttaa aaaactcatt gacatgggct tccgtgtatc tgtaacaggt ggtctagatg
    28381 tagatactct caaactcttt gaaggtgttg atgtctttac ctttatcgca ggtcgtggaa
    28441 ttacagaggc tgcggatcca gcaggagcag cgcgtgcctt caaggatgaa atcaaacgaa
    28501 tttgggggta aatcatggta cgtccaattg gaatttatga aaaggcaacc ccaacacact
    28561 gtacttggct agaacgttta aattttgcca aggagttagg ctttgatttt gtcgagatgt
    28621 ctattgacga acgtgacgag cgtttagcaa gacttgactg gagtaaggaa gaacgcttgg
    28681 aagttgtcaa agcaatctat gaaactggtg ttcgtattcc ttctatctgt ttttcaggcc
    28741 atcgtcgcta cccattgggt tcaaaagatc cagttctaga ggaaaaatct ctagaactca
    28801 tgaaaaaatg tatcgaatta gctcaagact tgggagttcg tacgattcaa ttagctggtt
    28861 acgatgttta ctatgaggaa aagtcacccc agacacgcca acgttttatc aaaaatttga
    28921 gaaaagcctg tgactgggct gaagaagctc aggtggtact tgctattgaa attatggatg
    28981 atcctttcat caatagcatc gaaaaatatt tggctataga aaaagagatt gactctccct
    29041 tcctctttgt atatccagat attggtaatg tgtctgcatg gcataatgat atctatagtg
    29101 agttttatct tggtcatcat gccatcgcag ctctccatct caaggatact tatgcagtga
    29161 cagaaagttc aaagggccag ttccgagatg taccttttgg gcaaggttgt gtcaaatggg
    29221 aagaagcttt cgatatttta aaggaaacca attataatgg acctttccta atcgaaatgt
    29281 ggtctgaaaa ttgtgaaaca gtagaagaaa cacgcgcagc cattcaagag gcgcaagctt
    29341 ttctctatcc actcattaag aaagcaggtt tgatgtaaga tgaatcaagt aatcaatgct
    29401 atgcgtaaac gagtttgtga tgccaatcaa tcattgccaa aacatggact tgtcaaattt
    29461 acctggggga atgtatctga agtcaatcgc gaactcggtg tcattgttat caaaccatca
    29521 ggcgtggatt atgacgaatt gacacctgaa aacatggtag tgactgatct agatggtaag
    29581 atcctagaag gggatttaag accatcttcc gacctcccaa ctcatgtgca attatataag
    29641 gcttggtcag aaattggtag tgtggttcac acccattcga cagaagctgt tggttgggct
    29701 caggcaggtc gtgatattcc tttctacgga acaacccatg cagattattt ctacggttca
    29761 atcccttgcg cccgtagttt gaccaaggac gaagtagaag tggcctatga aaaagatact
    29821 ggcctggtta tcgtagaaga atttgaacat cgcggactta acccggttga agtaccagga
    29881 attgttgtac gcaatcacgg tccattcacc tggggcaaaa atccagagaa tgctgtttat
    29941 cactctgtcg tactagagga agtatcaaag atgaatcgct ttacagaaca aatcaatcca
    30001 agagttggac ctgctcccca gtacatacta gaaaaacact accaacgtaa acatggacca
    30061 aatgcttatt atggtcaaaa gtaagaacga tgaaggagga gaaaaagata aatttagctc
    30121 ctctttttac atttgatttt tattgagagt aaagttggag ttgaagtaat tttgaaagat
    30181 tttttagaaa tagcgcttga tatatatggt aaaataaaaa gaattgctgt gatatcaata
    30241 gatttggggg attttttaat atggtactgg ataaggcaag ttgtgatttg cttcaatatt
    30301 tgatggatca agaaacgtcc aaaacgatta tggcgatttc gaaagatttg aaagagtcaa
    30361 gaaggaaaat ttattatcac attgacaaaa tcaatgctgc tctggttgac gaggcgcttc
    30421 acatcattag tattccacga attggtattc acttaacgga agagcagaga gatgcttgtt
    30481 gtaaactatt atcggaagta gattcgtacg attatatcat gagtgcgcat gaacgtatga
    30541 tgataatgtt actatggata ggtatttcta aagaacgtat tacgattgaa aaattgatag
    30601 agttaacaga ggtatctagg aatactgttc tcaatgattt gaatagtatt cgttatcaac
    30661 taactttgga acaatatcag gtgatcttgc aagtgagcaa gtcacaggga taccaccttc
    30721 atgcccaccc tcttaataaa attcagtatc ttcaatcgct tctatatcat atttttatgg
    30781 aagaaaatgc cacttttgta tctattttag aagataagat gaaagagagg ttagatgatg
    30841 agtgtttgct ttctgttgaa atgaaccaat tttttaagga acaggttcct ttagttgaac
    30901 aagatttagg gaagaaaata aaccatcatg aaataacttt tatgttgcag gttctacctt
    30961 atttgctgtt aagctgtcat aatgttgaac agtatcaaga aagacatcag gatatagaga
    31021 aagaattttc tttgataaga aaaagaatag agtatcaggt gtctaagaaa ttaggagaac
    31081 ggttgtttca aaagtttgaa atttctttgt caggacttga agtttctctt gtagctgttc
    31141 tcctcctctc ctatcgtaag gatttggata ttcatgcaga aagtgatgat tttcggcaat
    31201 taaaacttgc tttagaagaa tttatctggt attttgaatc acaaatccga atggagattg
    31261 agaacaagga tgatttgtta cgaaatttga tgatccactg taaagccttg ttatttagaa
    31321 agacttacgg tattttttct aaaaatcctc taacaaaaca aattcgatcc aagtatggag
    31381 aattattttt agtcactaga aaatctgcgg aaattttaga aggagcatgg tttattcggc
    31441 taacagacga tgatattgcc tatttgacga ttcatattgg aggattttta aagtatacac
    31501 catcgtctca aaaaaatatg aaaaaagttt atctcgtttg tgatgaaggt gttgcggttt
    31561 cgagactttt gctgaaacaa tgcaaacttt attttccaaa tgagcaaatt gacactgtat
    31621 ttacaacaga acaatttaag agtgtggaag atattgcaca agttgatgta gtgattacta
    31681 ctaatgatga tttggatagc agatttccga ttttaagggt taatcctatc cttgaagcag
    31741 aagatatttt gaaaatgcta gactatctta aacacaatat atttcgtaat aagagcaaaa
    31801 gtttcagtga aaatctttct agtcttattt cgtcttatat tgtagacagc aagttggcta
    31861 gtaagttcca agaagaggtt caaacactta taaatcaaga aatagtagtt caagcttttt
    31921 tggaagatat ttgaaggaca gtccaatgat gaacacaaac ctgtgttttt cttggtcttt
    31981 tttagtgttt tgaagggtgg tatactaatc tcaaagataa caattatatc caaaggaggc
    32041 aacatatgcc aaacgtcaaa gaaattacaa gagagtcatg gattttagcc actttcccag
    32101 agtggggaac atggttgaac gaagaaatcg aagaagaagt cgtacctgaa ggcaattttg
    32161 ccatgtggtg gctaggcaac tgtggtactt ggattaagac accagctggt gctaacgttg
    32221 tcatggacct ttggtcaaac cgtggaaaat caaccaaaaa agtgaaagat atggttcgtg
    32281 ggcaccaaat ggcaaatatg gcaggtgttc gtaagttgca accaaacttg cgtgttcagc
    32341 caatggttat cgatccattt gctatcaacg aactagacta ttacttagtt tcacacttcc
    32401 acagtgatca tatcgaccca tacacagctg cagcaattct caacaattct aagttagagc
    32461 atgttaagtt tatcggtcct taccactgtg gacgaatctg ggaaggatgg ggtgttccaa
    32521 aagaacgtat catcgttgtt aaaccaggtg acactatcga attaaaagat atgaagattc
    32581 atgcagtaga atcatttgac cgtacttgct tggtaactct cccagtgaac ggtgctgatg
    32641 agacaggcgg tgaacttgct ggcttggctg ttacagatga agaaatggct caaaaggctg
    32701 ttaactatat ctttgaaaca ccaggtggaa ccatctatca tggtgcagat tctcacttct
    32761 caaactattt tgcaaaacat ggtaaagact ttaaaattga tgttgctttg aataactatg
    32821 gtgaaaatcc ggtaggtatc caagacaaaa tgacatctat cgatcttctt cgtatggcag
    32881 aaaatctgcg taccaaagtc attatcccag ttcactatga tatctggtct aacttcatgg
    32941 cttctactaa tgagattcta gaactttgga aaatgcgaaa agatcgcttg caatacgatt
    33001 tccatccatt tatctgggaa gttggcggta agtacactta tcctcaagat caacacttag
    33061 tagaatacca tcatccacgt ggttttgatg attgttttga acaagactct aacattcaat
    33121 ttaaagcttt gctataatat aaaaatattc tttggaggtt atccgtatgt tgcatgatac
    33181 ggataatttt catataatag taaaatagaa tgtgtgattc aataatcacc tcaaatagaa
    33241 aggaaattct atgtcaaatc tatctgttaa tgcaattcgt tttctaggta ttgacgccat
    33301 taataaagcc aactcaggtc atccaggtgt ggttatggga gcggctccga tggcttacag
    33361 cctctttaca aaacaacttc atatcaatcc agctcaacca aattggatta accgcgaccg
    33421 ctttattctt tcagcaggtc atggttcaat gctcctttat gctcttcttc acctttctgg
    33481 ttttgaagat gtcagcatgg atgagattaa gagtttccgt caatggggtt caaaaacacc
    33541 aggtcaccca gaatttggtc atacggcagg gattgatgct acgacaggtc ctctagggca
    33601 agggatttca actgctactg gttttgccca agcagaacgt ttcttggcag ccaaatataa
    33661 ccgtgaaggc tacaatatct ttgaccacta tacttacgtt atctgtggag acggagactt
    33721 gatggaaggt gtctcaagcg aggcagcttc atacgcaggt ttgcaaaaac ttgataagtt
    33781 ggttgttctt tatgattcaa atgatatcaa cttggatggt gagacaaagg attcctttac
    33841 agaaagtgtt cgtgaccgtt acaatgccta cggttggcat actgccttgg ttgaaaatgg
    33901 aacagacttg gaagccatcc atgctgctat cgaaacagca aaagcttcag gcaagccatc
    33961 tttaattgaa gtgaagacgg ttattggata tggttctcca aacaaacaag gaactaatgc
    34021 tgtacacggc gcccctcttg gagcagatga aactgcatca actcgccaag ccctcggttg
    34081 ggactacgaa ccatttgaaa ttccagaaca agtatatgct gatttcaaag aacatgttgc
    34141 agaccgtggc gcatcagctt atcaagcttg gactaaatta gttgcagatt ataaagaagc
    34201 tcatccagaa ctggctgcag aagtagaagc catcatcgac ggacgtgatc cagtcgaagt
    34261 gactccagca gacttcccag ctttagaaaa tggtttttct caagcaactc gtaattcaag
    34321 tcaagatgcc ttgaatgttg tggcagctaa attaccaacc ttcctaggtg gatcagctga
    34381 ccttgctcac tcaaacatga cttatatcaa gacggatgga cttcaagacg ataccaatcg
    34441 cttgaatcgt aacattcagt ttggtgttcg tgaatttgca atgggaacaa tcttgaacgg
    34501 gatggccctt catggtggac ttcgtgtata cggtggaact ttcttcgtct tctctgacta
    34561 tgtgaaggca gctgtccgct tgtcagcctt acaaggactt cctgtgactt atgtctttac
    34621 ccatgattca atcgcagttg gggaagatgg tccgactcac gaaccagttg agcatttagc
    34681 aggtcttcgt gctatgccaa atctaaatgt tttccgtcca gcagatgcgc gtgaaacgca
    34741 agcagcttgg taccttgcag tgacaagtga gaaaacacca actgcccttg tcttgacacg
    34801 tcaaaacttg actgttgaag atggaacaga cttcgacaag gttgctaaag gtgcttatgt
    34861 tgtatatgaa aatgcagccg actttgatac catcttgatt gcgacaggtt cagaggttaa
    34921 tcttgctgtc tcagctgcta aagaattggc tagtcaaggc gaaaaaatcc gcgtaatcag
    34981 catgccatct acagatgtct ttgataaaca aaatgcagct tacaaggaag agattcttcc
    35041 aaatgcagtc cgccgtcgtg ttgcagtcga aatgggtgca agtcaaaact ggtacaaata
    35101 tgttggtctc gatggtgccg ttctaggtat tgataccttc ggagcctctg ccccagcacc
    35161 aaaagtattg gcagaatatg gctttactgt cgaaaatctt gtaaaagttg ttcgaaattt
    35221 gaaataatcc taaaaatcag ggcgtaagct ctggtttttc ttaccagaaa agtaaggtac
    35281 aatcttgtaa aagtagctga aatttgatat agtagtccta tgtaaaagac aaaggagaaa
    35341 acaatgaatc caaatattac ttttttaatc atgcttgtag gtatgatggc cttgatgttc
    35401 tttatgcaac gttctcaaaa gaaacaagct caaaagcgta tggaaagctt aaataaacta
    35461 caaaaaggct atgaagtgat tacaatcggt ggactttatg gaacagtcga tgaagtagat
    35521 acggagaagg gaacaatagt tcttgacgta gatggagttt acttgacttt tgaactagct
    35581 gctatcaaga cagtattacc gctgaaagaa acagcttcac tagaaggcgc aattgaaaaa
    35641 taagacggga tcacgaactc ccgttttcta taaaagaaag gaaatgggat gaaaaaatta
    35701 gtctttgtct gtctgggaaa tatttgccgt agccctatgg ccgagtttgt tatgaaatca
    35761 atgacagata actacgaaat ccaaagtcga gcaacttcct cttgggaaca tggcaatccg
    35821 attcataagg ggactcaggg aatttttcaa gagtatgaga ttccttatga caagaacaag
    35881 acatcgcttc agattagtaa ggaagatttt gaagcctttg attatattat cggaatggac
    35941 gcttcaaata tttctgactt acgtcagatg tgtccagtag actgtcaaga taagatttac
    36001 tcattttcat ctgaaagtgt tccagaccct tggtatacag gagattttga agaaacctat
    36061 cgacgtgttc aagagggctg tcaagcttgg ttagaacgtt tagaaaagga gagttaaggt
    36121 ggaaaatctt acgaattttt acgaaaagta tcgtgtctat ctgactcgtc cacgtttaga
    36181 gcttttggca gtagttacca ttgttttctg tgctgtactc gtcttttttc taaatattcc
    36241 aggaaaaggt gtcttaaaac tcgataatgg aacgattgtt tatgatggca gtcttgtccg
    36301 tggtaaaatg aatggccaag gtaccattac cttccaaaat ggagaccaat atacaggtgg
    36361 cttcaacaat ggagccttca acggaaaagg tacctttcaa tctaaagaag gctggaccta
    36421 cgaaggtgat tttgtaaatg gtcaggctga aggaaaaggg aaactaacaa cagaacaaga
    36481 agtcgtttat gaaggaactt ttaaacaagg cgtttttcaa caaaaataaa gcctccttat
    36541 caaaggaggt attattagaa tcacaaggta agcgcttacc tgtaaatccc tttctttcca
    36601 aatccctctt ccaagcaagt ttgtgaaata aaaaatattt gaaataaatt tcacaaactt
    36661 caaagataaa acttgataag aaaagaaaat gagaaaagtt tcacaagagt ttaaaaattc
    36721 tttgtgaaat gtttatgaaa ctgtttacaa agttgaaata atgcgttata ataaacttgt
    36781 gaaaaaatta acaaaggata tcgttccttg aaagctatgg aggaaaatat ggctgataaa
    36841 aaaactgtga caccagagga aaagaaactc gttgctgaaa aacacgtaga tgagttggtt
    36901 caaaaagctc tagttgccct tgaagaaatg cgtaaattgg atcaagaaca agttgactac
    36961 atcgttgcca aagcatcagt agcagctttg gatgcccacg gagaattggc tttacatgcc
    37021 tttgaagaaa caggacgtgg tgtatttgaa gacaaagcaa ctaagaactt gtttgcttgt
    37081 gaacacgtag taaacaatat gcgccacact aagacagttg gcgttatcga agaagacgat
    37141 gtaacaggat tgactcttat tgctgaacca gttggtgttg tttgtggtat tactccaaca
    37201 acaaacccaa catcaacagc aatcttcaaa tcattgattt cattgaagac acgtaaccca
    37261 atcgtctttg ccttccatcc atcagcacaa gaatcatctg ctcatgcagc tcgtatcgtc
    37321 cgcgatgcag ctatcgcagc tggtgctcct gaaaactgtg tgcaatggat tactcaacca
    37381 tctatggaag caacaagtgc ccttatgaac cacgaaggtg ttgcgacaat ccttgcaaca
    37441 ggtggtaatg ccatggttaa ggcggcttat tcatgtggta aaccagctct tggggtaggt
    37501 gccggaaacg ttccagctta tgttgaaaaa tcagcaaaca ttcgtcaagc agcacacgat
    37561 atcgtcatgt ctaaatcatt tgataacggt atggtctgtg catctgaaca agcagttatc
    37621 attgataaag aaatttacga tgaatttgta gcagagttca aatcttacca cacttacttt
    37681 gtaaacaaaa aagaaaaagc tcttcttgaa gagttctgct tcggcgtcaa agcaaacagc
    37741 aaaaactgtg ctggtgcaaa attgaacgct gacatcgttg gtaaaccagc aacttggatt
    37801 gcagaacaag caggatttac agttccagaa ggaacaaaca ttcttgctgc agaatgtaaa
    37861 gaagttggcg aaaatgagcc attgactcgt gaaaaattgt caccagttat tgcagttttg
    37921 aaatctgaaa gccgtgaaga tggtattact aaggctcgtc aaatggttga atttaacggt
    37981 cttggacact cagcagctat ccacacagct gacgaagaat tgactaaaga atttggtaaa
    38041 gctgttaaag ctattcgtgt tatctgtaac tcaccttcta cttttggtgg tatcggggac
    38101 gtttacaatg ccttcttgcc atcattgaca cttggatgtg gttcttacgg acgcaactca
    38161 gttggggata acgttagtgc cattaacctc ttgaatatca aaaaagtcgg aagacggaga
    38221 aataacatgc aatggatgaa acttccttca aaaacatact ttgaacgtga ttcaattcaa
    38281 taccttcaaa aatgtcgtga cgttgaacgt gtcatgatcg ttactgacca tgccatggta
    38341 gagcttggtt tccttgatcg tatcatcgaa caactggacc ttcgtcgcaa taaggttgtt
    38401 taccaaatct ttgcggatgt agaaccggat ccagatatca caactgtaaa ccgtggtact
    38461 gagattatgc gtgccttcaa accagatacc atcatcgcac tcggtggtgg gtctccaatg
    38521 gatgctgcca aagtaatgtg gctcttctac gagcaaccag aagtggactt ccgtgacctt
    38581 gtccaaaaat tcatggatat ccgtaaacgt gccttcaagt tcccattgct tggtaagaag
    38641 actaaattca tcgcgattcc aactacatct ggtacaggat ctgaagtaac accatttgcc
    38701 gttatctctg ataaagcaaa caaccgtaaa tacccaatcg ctgactactc attgacacca
    38761 actgtggcaa tcgtagaccc tgctttggta ttgacagttc caggatttgt tgctgctgat
    38821 actggtatgg acgtattgac tcacgcgaca gaagcatacg tatcacaaat ggctagtgac
    38881 tacactgatg gtttagcact tcaagccatt aaattggtct ttgaaaatct cgaaagctca
    38941 gttaagaatg cagacttcca ctcacgtgag aaaatgcata acgcttcaac aatcgctggt
    39001 atggcctttg ccaatgcctt cctaggtatt tctcactcaa tggcccataa gattggtgcg
    39061 caattccaca caatccacgg tcgtacaaat gctatcttgc ttccatacgt tatccgttac
    39121 aacggtacac gtccagctaa gacagcaaca tggcctaagt acaactacta ccgtgcagat
    39181 gaaaaatacc aagatatcgc acgcatgctt ggacttccag cttctactcc agaagaaggg
    39241 gttgaatctt acgcaaaagc tgtctacgaa ctcggtgaac gtattgggat ccaaatgaat
    39301 tttagagacc aaggaattga cgaaaaagaa tggaaagaac attctcgtga attatccttc
    39361 ctggcttatg aagaccaatg ttcaccagct aacccacgtc ttccaatggt agaccatatg
    39421 caagaaatca tcgaagatgc atactatggc tacaaagaaa gaccaggacg ccgtaaataa
    39481 ttgtttatca gtctagaagc aagacaaaaa ctcaatttga gggaaagatc cagtaatttt
    39541 tctatgataa aaggcatcct atcaaggttt ttgaatacct gataggatgc ctttttatga
    39601 tgttgaggcc tttttgccct ttttgaaaaa ctagaataga aacaaaatat atagcagatt
    39661 gaaactagaa tagtacatat ctgcttctaa aacattgtta gaattcgatt tgactgtcct
    39721 gatcgatttg ttctattctt atttcatttt actatactat ataaaaaata tagtataata
    39781 aaatgaatct aaaatagtac gaaacaattg ctaaaacatt tatagaaatt aattttactt
    39841 tcctgataga gttgtttaca tcttatttca attcactata gtttaattta agagtagtat
    39901 ttactaaggc ccaattaaaa tcaaagagca aacgagaaaa cgatgacaag gtgtgttgct
    39961 ttttgatttc taaagagtat aatgatagat ctctataaaa taagtgcgaa ggaaatgagc
    40021 ttttataatc ctttcgtttt aaaatactat ctcagatatt cttatatcga caagaagttt
    40081 ttgagtcatt ccctcatcat acatattaaa taaatagtgg ctcattcaat tttttactag
    40141 aataataagc tagtatagta aactgaaata agatataaac aaataaattg gagcttaaca
    40201 tctatttcca gcaatttttt agaaactgca gtggactatt ctaaattcaa cacattataa
    40261 aaactagagt aaaagaaaag gattggatct tgtgtaatgc aggatccaat cctttcaatc
    40321 attttgtcca acttttggag gttcctacaa tgtagccgtc attaataaag acagatggga
    40381 atgacagtgt tcctatttat tttgatagag atcgatgaat tctttagata gcaactgaat
    40441 aatctctgtt gaagccattt ggtcttctgc atgcataaat agcaaggaga atcctatttt
    40501 ttctccagta gcttcttttt gtatgagatt agagtgaatc ttgtgcgctt ctactaagga
    40561 gtcttccgct tcttcaactt taattttcgc ttcttttaaa tttcctgcct tagctagttg
    40621 gatggcttca ataaaggatg atttggctgc tccactattg gcaatgagct gaaaacagat
    40681 atattccatt tcttctgtca tcttatttct cctatccatg caagtgcttg ttccagaact
    40741 tttgctccat tcatcattcc gtaatcccgc atatcaatgg tatctacagg gatatttcct
    40801 gcaatttctt tcacagcaag taactcataa cgaatttgtg gcccaattag aatgacatct
    40861 gcttcatgga tattcttttt agcttctgtc attgattttg cttggataga aatttcaatc
    40921 ccacgttcag tcgcactttg ttgcattttt ttaacaagca tacttgtcga cattcccgca
    40981 ttacatacta ataaaatttg tttcataatc ttaaccttcc atttcttgtt caacaacttt
    41041 gtcattaact ttgataaatg gaatgtatag aagaactcca agtgcaaaga tgatgaattg
    41101 aactagaact gctctcacgt cccctgctgt tgctaaccat gcatttaaga atactggtgt
    41161 agtccaagga acttgtataa atgcaggact catgaatcct gtaactgttg ctaagtagct
    41221 gattaaaata ccaaggactg gaactgtgat aaatggaata gctaatgaaa tgttataaac
    41281 gattgggtaa ccgaataata ctggttcatt gatattgaag ataccaggtc caaaagataa
    41341 tttagccacg tttttagaga cagcattgcg actcactaag aatgttgcta ttaataaaca
    41401 taatgtagat ccactaccac ccattaaagc gaatgtttgt atttgtgata ggttgatgat
    41461 gtgtggaatg gcttgtccat tatttgctgc agtgatgttt tcagtaatgt taattaatag
    41521 taatggttct aggatggcac tgtaaataac tgcttggtga ataccaaata gccataacat
    41581 atttcctaaa gagtaaataa taatgacccc gattaagctt gtaccaatat gacgaattgg
    41641 ttcttgaata aagattgtaa tgattgagat taagttcatt ccagttatat tgaataataa
    41701 tgctgaaaca accccaaata aggagatgac ggtcatgact ggaagtaata cgctaaatga
    41761 tctactaaca gctggtggaa tattttcacc aaggttcatt tgtaaagctt taacgtttga
    41821 taattcaatg aataattctg ttgcaataat cgctacgata accccggcga acattgcgcc
    41881 tgtacctgtg ttgttgaatg aaagaacacc tgaaatgttt accgcatctt ttgctccgtc
    41941 aggaactaca gaaactgtat ttggcatcat cacaattaaa gaaactaatg atagcattga
    42001 tgctgctaac gggttttcga aatctctgtt tttagctaag aaataaccaa ccattacagc
    42061 aataatcata cctgaaatac ttaaagtacc gtttgcaatt gttattcccc aatattggaa
    42121 tcttgttaat gtatcccctt ggaaaatcca cttaaatacc gtgttgttca aaagaacgat
    42181 taaacctgcc aaaatatata atggcattac tgttacgaat gcatctctta gggtttttaa
    42241 atgaatttgg ttccctagtt taccagcaaa ggtggcaaat tgatctataa attttgagtt
    42301 tttcatctga atatctcctc tctttactcc tcaatttcta cttcaaaacc gttattgtca
    42361 cttactttgc gataccatct tcctgatctc ttgatggttc tcttttgcgt ttctaaatca
    42421 acggagataa atccgtaacg attcttatat gcattattcc aagaccagca atcaaatgcg
    42481 gtccaagcgt ggtatccaaa acagtgactt ccctcttcaa tggctttatg tagccatctt
    42541 aaatgttctt cataaaattc aatacgatac acgtcatcga taactccatt ttcaccgata
    42601 aaccgtgctt cgttttcaac acccattccg ttttcactga taaaccatgg aatattacca
    42661 tattctttct tcacaatcat agcaatatca taaatggctt tcggaaaaat ttcccaacca
    42721 cgatatggat tcatgcgacg ctccggccat tcatactctt tgaagtattg gtctggcatc
    42781 cagggcgtct gatattcctc aggatttgct tgtgcttgaa cacgttttgg atggtagtag
    42841 tttactccaa gaaaatcaac cgtatttgat ttcatcagtt gaagctcttt ttcggtatga
    42901 ctccataaca cgccatctct ctctagctgt tttaccaatc tttctgggaa agttccttta
    42961 acagctggat tcaagaagac tttgttaaag aagtcatctg taaatcgact tgcttctaag
    43021 tcttctggag aattacttct tggataagca ggtgtcaagt ttaaaataat cccaatcttt
    43081 ccatcaagtc ctaatgagcg atatagttga atcacttttg cactagcaag gtttagatta
    43141 tagatgactt gtacggcctc ttttcccttt ccttttagat ttggataatg gaaagcatat
    43201 aagtatcctg cttctggaat gaccattggc tcattgaaag ttgtccagta atgaacctta
    43261 tctccaaagc atgtgaaagc agtcttggca aacttcacga ataactccac tacatgtttg
    43321 ctttcccaac caccgtattt ttgaagaagt tccactggta aatcaaaatg atgtaaattc
    43381 atcacaagat ccatctggtt ctttttagct tcttcaatga tggcattgta gaaagcaata
    43441 ccttttggat caggctcacc tgtctctaaa ttcttgatga gtcgactcca ttggatggaa
    43501 gtgcggaaag aattaactcc aatttccttc atcaagtgga aatcttcggt gtaagtatga
    43561 aaaaagttac tggctacaag aggtccgaca ttatcgaaaa aatcttctgg atgcgttttg
    43621 aaccagtagt ccatcacatt ttcatgtact tttccatatt gaccttctgt ctgaggtccg
    43681 ctagaagcag ctccccacca aaacagatta ggaaatacta actttttttt catgctcaac
    43741 ctcctttcta ttattctata cataaagtat agcataattt taaaatttgt ctagacattt
    43801 ttaaaaattg ttgatacata tcttgtgttt gcctcatttc ttgaactttg ttatactact
    43861 attagaatat tatagagaga accagattaa atgagtacaa aatatttatt tatttacaat
    43921 gagattcgtg aaaagattct ttgtaataaa tataccatga acgaacaatt gcctgatgaa
    43981 atgacattag ctaaacagtt tgcctgtagt cgaatgacga tcaaaaaagc tttagacttg
    44041 ttagtttctg agggcttaat ttttagaaaa cgtgggcagg gaacctttgt tctctctcgt
    44101 ggcagctcaa aaagaaaatt aatcgttcca gaaagagata tccggggatt gacaaaaata
    44161 tctgaagatg ctcattctac aattgactcg aggattattc acttcaaatt agaatttgca
    44221 aatgaatttt tagcagaaaa actacaggtc gctttgcaga gtccagttta taatatttac
    44281 cgcctgcgta ttattgacgg taaaccttat gttctggaac aaacttatat gagtaccgat
    44341 gttattccag gtattactga agatatttta caaaaatcga tttacaatta cattgaagga
    44401 aagttaggat tgcatattgc cagtgctaca aaaatcttgc gagcttcttc tagttcagaa
    44461 aatgagcaac attacttaca gctccttcca acggaaccgg tatttgaagt agaacaagtg
    44521 gcttatttgg ataacggaac tccgtttgag tactcgatta gtcgtcatcg ctatgattta
    44581 tttgaattta attcttttgc attacgacat tcctcctagg agaaaatgtg aaaatgaagc
    44641 caatctttta cagactctag tttaagaaaa atttaaaaca gggcaagaag gtcccatcta
    44701 tgcttaaatg gtttctcttt tctaaataag atggctttaa aagagtgatc gttgtatcca
    44761 tcatgttgaa aaatatcttc gtatagctta tagagtaggt actgaaattg ttcacctgat
    44821 ctacttctta tagttattta gttttaaata gtgtttcaaa cattcttaca ctgacgagaa
    44881 gtttttgagt cttttcttgt aacacatata gtatactgtg gttagaatag tagactgtga
    44941 cttctaacaa attgctagaa atgaatttca atctcccaat ttatttgttc atatcttctt
    45001 ttaatatatt aaataaattc taaatcataa tcatttaaaa aaattttatt ttttattttt
    45061 cattacgaat aatatagatg aaggggaaag agtatgaaaa cagaactgtt tcttttgcta
    45121 ttagttcaaa aggagaaaaa atgaaagtag aaaatatttc gtatagggtg gatcatcgta
    45181 aattgtttga taatatttct tttgatactt cgagttcaga cgtgacatta attactggta
    45241 aaaatggtac aggaaagtca actttactat agtagattga aactagaata gtacacatct
    45301 acttctaaaa tattgttaga aatcgatttg actatcctga tctatttgtc ctgttcttat
    45361 ttcatttcac tatatctcaa attgagtatg acgaagtgcg ctcccatgtc ctgggaacgc
    45421 actttcttca tatttttcat attcttgaat ccatcgataa agactattgg gatgaatttt
    45481 taaagttgaa ctaatcattt ttacaggatg agatttacag cagagagttt gaaggcttta
    45541 tcaaaggttt ttcttggcat aatgactttt cctcgtttcc acttaatttt gtgtctactt
    45601 tattatacca agtccactct taagttagat aataaatcta acttaaggaa gctagaagga
    45661 tgagaatcca ggtggtcaag agtcccaaac ttaagctgat ggggacaccc agaataattt
    45721 gctttttgaa ggcaaggcca cgttcctcta tattgggaag tgagagttga atgagagaac
    45781 cagctgatga aaagggtgag atattagtag atagagcgcc aataacggtg gctgttgtga
    45841 gtaagtgaat atcaatctga ggattttgag cactgatgat agcaatgatg ggaaagaggg
    45901 ctggagctac aacggatagg gtggaactaa agagtgacat cactccggct atcacacaaa
    45961 agaacagagg taaccagaaa tgaggaatgg ttgttgtcat gaggtgccct atcagtgtga
    46021 ctaaacctga cttgaccgct agagacatta gtaagctcat gccgcagagc atgataattg
    46081 tagcccaggg aaccttagct aaaatggctt cttgcttccc taatttgagc cttaaggcga
    46141 ggcagaccat gagtattgag acaaagccaa tatcaaatgt tttttgataa gtagctatcc
    46201 aggcgatgtt tgggaaaatg agatgcaaca agggaaaaag ccaaaccaaa accatgctgc
    46261 tgatcatgag caaggtggtt tgtctttgaa ccttgctgag gagtggtggt tggtcaatag
    46321 tcaaggatga gtttgttctt cccttactat agtgactgta acaggataat aaaagcaaga
    46381 cgatgagtgg gtagataatg ctgacgataa agatatgatt gccaagtgaa aaagcttgct
    46441 cttcccatcc catttgctta aacaggcctt gaaagacaat gcctgagcta ctggttatca
    46501 aattagcccc tcctgaagct ccccaattga cggcttgagc tccaatcaaa gggtgtttgt
    46561 ccgctttttg acagagggta atcgctagag gacagcaaac ggccatagta gtgaaaaatc
    46621 cagcacctaa agcagacaaa agggttgcca tcaggtataa aatcatgtag agggcgttag
    46681 ggtgggtgcg tgtgcggtag agaatgtgtt gagccaaaac atcaagagta ccgttagttg
    46741 ttgcaacgtt ataaaagaga gagacgctaa aaatggtaaa aaagagtgag gttggccaaa
    46801 aatgaagaag ttctttgggg cttaatccca tgagagtggt tgcgatgagg taagaaaaag
    46861 caatagccag caggccaata ttgattttgg tgcggtaacc aattccaatg gctagagcaa
    46921 tggcgctaat cattattaaa tgaatcattg aattgtcctt tcagttagaa tatggaaata
    46981 ggttggcaat tttggcgctc aaaagaccac ctgtttccta ttggtacttg actattatac
    47041 acaaaaaaaa tacaattgtc ttgacaattg tattgacact tgttagaatt aaaaatgagg
    47101 tattcaggct tgtgatttcc tatggaagtt aatagtaatt gcctctagtg cttacaagtg
    47161 atattaaaaa tagaggactt agtgatgtca atcatttcaa ctgatttaac cccttttcaa
    47221 atagatgata cattgaaagc agccttgcga gaagatgttc attccgaaga ttacagtacc
    47281 aatgccattt ttgatcatca tggccaagcc aaggtgtcgc tttttgccaa ggaagctggt
    47341 gttttagcgg gactaaccgt ttttcaaagg gtttttaccc tatttgatgc cgaggtgacc
    47401 ttccagaatc ctcatcaatt taaggatggg gatcgtttga ctagtggcga tttggtttta
    47461 gaaatcatag gctcggtgag aagtctctta acatgtgaac gcgttgcctt gaatttttta
    47521 caacatttat cagggattgc ttcgatgaca gctgcttatg tagaagcctt aggcgatgat
    47581 tgcattaagg tatttgatac tcgaaaaact actcctaatt tacgtctttt tgagaaatat
    47641 gccgtgagag ttggcggtgg ctataatcat cgctttaatt tatcagatgc tatcatgcta
    47701 aaagacaatc acattgcggc agtaggtagt gttcagaagg caattgctca agcgcgtgcc
    47761 tatgcccctt ttgtgaaaat ggtcgaggtg gaagtggaaa gccttgctgc tgccgaagaa
    47821 gctgcggcgg cgggtgctga tattatcatg ttggataata tgtcattgga acagattgaa
    47881 caggccatta ccctaattgc aggacgttct cggattgaat gttctggaaa tattgatatg
    47941 accactatta gccgttttcg tggtttagcg attgattacg tctccagtgg tagtttaacc
    48001 catagtgcta agagtcttga tttttccatg aagggtttaa cctaccttga tgtctaagtt
    48061 gtaaaataaa ctaacttttt aaaggatgtc tttcctctag aacgagtttt atgtcagata
    48121 gtttaaacgc ctcttcaaat atagtaaaat gaaccaaaaa tagtacacaa tgtggtataa
    48181 tcttcttatg gcatattcaa tagattttcg taaaaaagtt ctctcttatt gtgagcgaac
    48241 aggtagtata acagaagc
//
LOCUS       DBEJHE010000014        48167 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC4 isolate 671759
            SAMN38261586-rid24793303.denovo.14, whole genome shotgun sequence.
ACCESSION   DBEJHE010000014 DBEJHE010000000
VERSION     DBEJHE010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261586
            Sequence Read Archive: SRR26833752
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 48167)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48167)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576136.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576136.1
            Genome Coverage       :: 109x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 19:48:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,067
            CDSs (total)                      :: 2,029
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 131
            CDSs (without protein)            :: 131
            Pseudo Genes (ambiguous residues) :: 0 of 131
            Pseudo Genes (frameshifted)       :: 64 of 131
            Pseudo Genes (incomplete)         :: 59 of 131
            Pseudo Genes (internal stop)      :: 46 of 131
            Pseudo Genes (multiple problems)  :: 32 of 131
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48167
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261586-rid24793303.denovo.14"
                     /strain="GPSC4"
                     /isolate="671759"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            <1..222
                     /locus_tag="ACL3EZ_001079"
     CDS             <1..222
                     /locus_tag="ACL3EZ_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0392662.1"
                     /translation="TIKFLFIRLFDTSTLMKRRIFFLFALDVIVYLFLGYLLVIQKAG
                     YLFSVLLLFSNFSVPFIKEKEYELFKNSK"
     gene            695..892
                     /locus_tag="ACL3EZ_001080"
     CDS             695..892
                     /locus_tag="ACL3EZ_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0392663.1"
                     /translation="MKHFFAGIGEIKLVGYLLYICVGLAPLFHIYVIGSELSFVKIVL
                     SILGVIFVSMLTIARIYRTFL"
     gene            1348..1851
                     /locus_tag="ACL3EZ_001081"
     CDS             1348..1851
                     /locus_tag="ACL3EZ_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBECR4 domain-containing protein"
                     /protein_id="HGR0392664.1"
                     /translation="MKLLDCILDYQERFNGKTCQVSTNYKYLETFKVNFCLTDLHHLF
                     GLHKITRDFASHTISVIQTGVFILEDFRNILLYNDVIERISLYEFIGDIFYSKLTSYC
                     IVAKDLSKNTMKLDVIFFEDKNKRSAVLGLRRDKSGVFKPVTLHFTSAKKYAKVRKTN
                     VKEMKWL"
     gene            2137..4230
                     /gene="pspA"
                     /locus_tag="ACL3EZ_001082"
     CDS             2137..4230
                     /gene="pspA"
                     /locus_tag="ACL3EZ_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal surface protein A"
                     /protein_id="HGR0392665.1"
                     /translation="MNKKKMILTSLASVAILGAGFVTSQPTFVRAEEAPVASQSKAEK
                     DYDAAVKKSEAAKKAYEEAKKKAEDAQKKYDEDQKKTEEKAENEKKAAADLNEATEVH
                     QKAYVRYFEIQRAKDSKKYKNNRDKYNKDLAEADQKIKDTKTVLDEKQSKFYAVRAVV
                     VPEAKELAVTKQKAEETKKGAEVAKEKYDKAAQEVEVAKKEVEAEEAELDKKVAELQN
                     KVADLEKEIADAEKTVADLEKEVAKLEKDVEGFKESDGEYAKFYLEAAEKDLATKKAK
                     LAEAKIKAATKKAELEPELEKAEAELENLLSTLDPEGKTQDELDKEAAEAELNKKVEA
                     LQNQVAELEEELSKLEDNLKDAETNNVEDYIKEGLEEAIATKQAELEKTQKELDAALN
                     ELGPDGDEEETPAPEAPAEQPKPEKPAEETPAPAPKPEKSADQQAEEDYARRSEEEYN
                     RLTQQQPPKAEKPAPAPAPKPEQPAPAPKTGWKQENGMWYFYNTDGSMATGWLQNNGS
                     WYYLNSNGAMATGWLQYNGSWYYLNANGAMATGWAKVNGSWYYLNANGAMATGWLQYN
                     DSWYYLNANGAMATGWAKVNGSWYYLNANGAMATGWAKVNGSWYYLNANGAMATGWAK
                     VNGSWYYLNANGSMATGWVKDGDTWYYLEASGAMKASQWFKVSDKWYYVNGLGALAVN
                     TTVDGYKVNANGEWV"
     gene            4631..5752
                     /gene="mnmA"
                     /locus_tag="ACL3EZ_001083"
     CDS             4631..5752
                     /gene="mnmA"
                     /locus_tag="ACL3EZ_001083"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0016783 - sulfurtransferase activity
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HGR0392666.1"
                     /translation="MSDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVVAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMTLGADYVATGHYARVARDEDGTVHMLRGVDNGKDQTYFLSQLS
                     QEQLQKTMFPLGHLEKPEVRRLAEEAGLSTAKKKDSTGICFIGEKNFKNFLSNYLPAQ
                     PGRMMTVDGRDMGEHAGLMYYTIGQRGGLGIGGQHGGDNAPWFVVGKDLSKNILYVGQ
                     GFYHDSLMSTSLEASQVHFTREMPEEFTLECTAKFRYRQPDSKVTVHVKGDKAEVIFA
                     EPQRAITPGQAVVFYDGEECLGGGLIDNAYRDGQVCQYI"
     gene            5893..6348
                     /locus_tag="ACL3EZ_001084"
     CDS             5893..6348
                     /locus_tag="ACL3EZ_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HGR0392667.1"
                     /translation="MTQQDFRTKVDNKVFGVRATALILQNRKLLVTKDKGKYYIIGGA
                     IQVNEKTEDAVVREVKEELGVKSQAGQLAFVVENRFEVDGVSYHNIEFHYLVDLLEDA
                     PLTMQEDEKRQPCEWIDLDKLEDIQLVPAFLKTALPDWEGQLRHIHLEE"
     gene            6358..8271
                     /gene="mnmG"
                     /locus_tag="ACL3EZ_001085"
     CDS             6358..8271
                     /gene="mnmG"
                     /locus_tag="ACL3EZ_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002098 - tRNA wobble uridine modification
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HGR0392668.1"
                     /translation="MTYHFTEEYDIIVIGAGHAGVEASLAASRMGCKVLLATINIEML
                     AFMPCNPSIGGSAKGIVVREVDALGGEMAKTIDKTYIQMKMLNTGKGPAVRALRAQAD
                     KELYSKEMRKTVENQENLTLRQTMIDEILVEDGKVVGVRTATHQEYAAKAVIVTTGTA
                     LRGEIIIGDLKYSSGPNHSLASINLADNLKELGLEIGRFKTGTPPRVKASSINYDVTE
                     IQPGDEAPNHFSYTSRDEDYVKDQVPCWLTYTNGTSHEIIQNNLHRAPMFTGVVKGVG
                     PRYCPSIEDKIVRFADKERHQLFLEPEGRNTEEVYVQGLSTSLPEDVQRDLVHSIKGL
                     ENAEMMRTGYAIEYDMILPHQLRATLETKKISGLFTAGQTNGTSGYEEAAGQGIIAGI
                     NAALKIQDKPELILKRSDGYIGVMIDDLVTKGTIEPYRLLTSRAEYRLILRHDNADMR
                     LTEMGREIGLVDDERWARFEIKKNQFDNEMKRLDSIKLKPVKETNAKVEEMGFKPLTD
                     AVTAKEFLRRPEVSYQDVVAFIGPAAEDLDDKIIELIETEIKYEGYISKAMDQVAKMK
                     RMEEKRIPANIDWDDIDSIATEARQKFKLINPETIGQASRISGVNPADISILMVYLEG
                     KNRSISKTLQKSK"
     gene            complement(8650..10329)
                     /locus_tag="ACL3EZ_001086"
     CDS             complement(8650..10329)
                     /locus_tag="ACL3EZ_001086"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HGR0392669.1"
                     /translation="MAYTLKPEEVGVFAIGGLGEIGKNTYGIEYQDEIIIVDAGIKFP
                     EDDLLGIDYVIPDYSYIVDNIDRVKAVLITHGHEDHIGGIPFLLKQANVPIYAGPLAL
                     ALIRGKLEEHGLLRNAKLYEINHNTELTFKNLKATFFRTTHSIPEPLGIVIHTPQGKI
                     VCTGDFKFDFTPVGEPADLHRMAALGEEGVLCLLSDSTNAEVPTFTNSEKVVGQSIMK
                     IIQGIEGRIIFASFASNIFRLQQATEAAVKTGRKIAVFGRSMEKAIVNGIDLGYIKAP
                     KGTFIEPNEIKDYPAGEVLILCTGSQGEPMAALSRIANGTHRQVQLQPGDTVIFSSSP
                     IPGNTTSVNKLINIISEAGVEVIHGKVNNIHTSGHGGQQEQKLMLCLIKPKYFMPVHG
                     EYRMQKVHAELAVDTGVEKDNIFIMSNGDVLALTADSARIAGHFNAQDIYVDGNRIGE
                     IGAAVLKDRRDLSEDGVVLAVATVDFKSQMILSGPDILSRGFVYMRESGDLIRQSQRI
                     LFNAIRIALKNKDASVQSVNGAIVNAIRPFLYENTEREPIIIPMILTPDEE"
     gene            complement(10331..10564)
                     /locus_tag="ACL3EZ_001087"
     CDS             complement(10331..10564)
                     /locus_tag="ACL3EZ_001087"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002947111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase subunit epsilon"
                     /protein_id="HGR0392670.1"
                     /translation="MIYKVFYQETKERSPRRETTRALYLDIDASSELEGRITARQLVE
                     ENRPEYNIEYIELLSDKLLDYEKETGAFEITEF"
     gene            10844..11059
                     /locus_tag="ACL3EZ_001088"
                     /pseudo
     CDS             10844..11059
                     /locus_tag="ACL3EZ_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282487.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(11382..11534)
                     /gene="cibB"
                     /locus_tag="ACL3EZ_001089"
     CDS             complement(11382..11534)
                     /gene="cibB"
                     /locus_tag="ACL3EZ_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000977347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibB"
                     /protein_id="HGR0392671.1"
                     /translation="MMKNLNNYREISNKELQEIKGGFGVGVGIALFMAGYTIGKDLRK
                     KFGKSC"
     gene            complement(11536..11721)
                     /gene="cibA"
                     /locus_tag="ACL3EZ_001090"
     CDS             complement(11536..11721)
                     /gene="cibA"
                     /locus_tag="ACL3EZ_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000180803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibA"
                     /protein_id="HGR0392672.1"
                     /translation="MTNFDILDNQFLSLSENELSDIDGGLAPLVIFGVAVSWKAIAGG
                     TALIGSGLAAGYFLGGD"
     gene            11899..12582
                     /gene="tsaB"
                     /locus_tag="ACL3EZ_001091"
     CDS             11899..12582
                     /gene="tsaB"
                     /locus_tag="ACL3EZ_001091"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000865689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HGR0392673.1"
                     /translation="MKVLAFDTSSKALSLAILEDKQVLAETTINIKKNHSITLMPAID
                     FLMASLDWTPKDLDRIVVAEGPGSYTGLRIAVATAKTLAHTLNIELVGMSSLLALVPR
                     QKEGLVVPIMDARRNNVYAGFYENAKPVLPEAHLSFAEVLEQVKDAEQVTFVGEVGAF
                     VEQIQEQLPQASYQETLPNAANLALWAWDKEADSLHDFVPNYLKRVEAEENWLKNHTE
                     SGESYIKRL"
     gene            12579..13016
                     /gene="rimI"
                     /locus_tag="ACL3EZ_001092"
     CDS             12579..13016
                     /gene="rimI"
                     /locus_tag="ACL3EZ_001092"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008999 -
                     peptide-alanine-alpha-N-acetyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HGR0392674.1"
                     /translation="MIEIKRIQQQPDLAKAIYAVMIAVYPVSPWTLEQIQADLFQDQT
                     WYALAYDGAEVIGFLAVQETLFEAEVLQIAVKGAYQGKGIASALFAQLPTDKEIFLEV
                     RKSNQRAQAFYKKEKMAVIADRKAYYHDPVEDAIIMKREIDEG"
     gene            13006..14016
                     /gene="tsaD"
                     /locus_tag="ACL3EZ_001093"
     CDS             13006..14016
                     /gene="tsaD"
                     /locus_tag="ACL3EZ_001093"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HGR0392675.1"
                     /translation="MKDRYILAFETSCDETSVAVLKNDDELLSNVIASQIESHKRFGG
                     VVPEVASRHHVEVITACIEEALAEAGITEEDVTAVAVTYGPGLVGALLVGLSAAKAFA
                     WAHGLPLIPVNHMAGHLMAAQSVEPLEFPLLALLVSGGHTELVYVSEAGDYKIVGETR
                     DDAVGEAYDKVGRVMGLTYPAGREIDELAHQGQDIYDFPRAMIKEDNLEFSFSGLKSA
                     FINLHHNAEQKGESLSTEDLCASFQAAVMDILMAKTKKALEKYPVKTLVVAGGVAANK
                     GLRERLAAEITDVKVIIPPLRLCGDNAGMIAYASVSEWNKENFAGWDLNAKPSLAFDT
                     ME"
     gene            complement(14056..15362)
                     /locus_tag="ACL3EZ_001094"
                     /pseudo
     CDS             complement(14056..15362)
                     /locus_tag="ACL3EZ_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011680908.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(15698..16389)
                     /locus_tag="ACL3EZ_001095"
                     /pseudo
     CDS             complement(15698..16389)
                     /locus_tag="ACL3EZ_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001839528.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            16632..17186
                     /locus_tag="ACL3EZ_001096"
     CDS             16632..17186
                     /locus_tag="ACL3EZ_001096"
                     /inference="COORDINATES: protein motif:HMM:NF024831.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HGR0392676.1"
                     /translation="MQYSCGKININIPDGYGDIKDIVFSAHIIVRYNNGHCGGIDPHI
                     IGLCKKQIRRMSLYPILIIVSRDSKVIDDYKNLDIAYVDCTQCSNNFETALHVKNILK
                     LLKIQLIHCHGYSTNYFLYMLKKLDKNGFGKVKTVITCHGWVEYNLKKKFLTYFDFWT
                     YSMGDAFICVSETMKKRLESIIKK"
     gene            17314..17838
                     /locus_tag="ACL3EZ_001097"
     CDS             17314..17838
                     /locus_tag="ACL3EZ_001097"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF012744.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HGR0392677.1"
                     /translation="MDPEKRPDRFLEFAEKLFLVREDVIFIMAGNGSMWAALKEKICH
                     LKCRDNFRLLGEIYPATIVYQISDLLYIPSDTEGIPMCVLESMSQGTPVLASNVGGLS
                     EIIEHRIDGFLFEKEDVEGVCACANFLLNDSEYLKYIGENSKSKIRKHFSVQKMFVET
                     MRVYDELLEKSSHG"
     gene            17831..18784
                     /locus_tag="ACL3EZ_001098"
     CDS             17831..18784
                     /locus_tag="ACL3EZ_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HGR0392678.1"
                     /translation="MDRNIDQELVSIIIPTHNRYESLIRAVKSCLHQSYKNIEVIIID
                     DNYSNVNLRNKIIHQFGYTNHRIKLILSNEDLGATNARNIGIKNSRGKYISFLDDDDE
                     YMSDRILKLMACFKKSRMKNLALVYSYGIIIYPNGTREEEKTDFVGNPLFVQMVHNIA
                     GTSFWLCKKEVLELINGFEKIDSHQDGVVLLKLLAQGYQIDIVREFLVNYYAHSKENG
                     ITGVTQKTINADEEYYNYCRKYFNLLSFNERILVTKKYYSLNIKRLLLIGDKCKALKV
                     IKKAREEKIFNEFLFLKYMLLYHFGFFYCIYDNYVQLKFRK"
     gene            18794..20410
                     /locus_tag="ACL3EZ_001099"
     CDS             18794..20410
                     /locus_tag="ACL3EZ_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGR0392679.1"
                     /translation="MYTIIKSNIKKFSLLTIFIVAGQLLLIYAATINALVLNELIAMN
                     LERFLKLSIYQMIVWCGIIFLDWVVKNYQVEVIQEFNLEIRNRVATDISNSTYQEFHS
                     KSSGTYLSWLNNDVQTLNDQAFKQLFLVIKGISGTIFAVVTLNHYHWSLTVATLFSLM
                     IMLLVPKIFASKMREVSLNLTNQNEAFLKSSETILNGFDVLASLNLLYVLPKKIKEAG
                     ILLKMVIQRKTTVETLAGAISFFLNIFFQISLVFLTGYLAIKGIVKIGTIEAIGALTG
                     VIFTALGELGGQLSSIIGTKPIFLKLYSINPIESNKMNDIEPNEVNRDFPLYEAKNIC
                     YKYGDKEILKNLNFCFQRNEKYLILGESGSGKSTLLKLLNGFLRDYSGELRFCGDDIK
                     KTSYLNMVSNVLYVDQKAYLFEGTIRDNILLEENYTDEEILQSLEQVGLSVKDFPNNI
                     LDYYVGDDGRLLSGGQKQKITLARGLIRNKKIVLIDEGTSAIDRRTSLAIERKILDRE
                     DLTVIIVTHAPHPELKQYFTKIYQFPKDFI"
     gene            20759..21187
                     /locus_tag="ACL3EZ_001100"
     CDS             20759..21187
                     /locus_tag="ACL3EZ_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001290269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0392680.1"
                     /translation="MSDIVEMSKKISDLNDKKEFHKKNCELRFQDSVLDNINSVPSTT
                     HLFSCLNIQTLVKIILYIFRYNSCMKIFNFRDKELIFFNKIVNGLIQNIEENLEDDIE
                     RILKYLYICLFNEIFIIKNKVNFFDDVEFNQTLSEFLDKL"
     gene            21199..21948
                     /locus_tag="ACL3EZ_001101"
     CDS             21199..21948
                     /locus_tag="ACL3EZ_001101"
                     /EC_number="3.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000069862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0019213 - deacetylase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HGR0392681.1"
                     /translation="MSNNTKYIFLSPHLDDAIFSCGDYISKLTSEGEIVLVITIFSGY
                     PLSQQLQPSAKQFHKLCNLGKYPIEERKKEDRLACERLQCDFRHLSYYECLYRKDRNG
                     NFLYRHIYSELKNEDTLKNDIIKELLMHLDDKCVVYCPLSLGDHVDHVFVNSIGRALE
                     FMRYKVIYYEDFPYVSDSSMVSYMGKTKELKMYQEELDEKHYIDRISSILCYKSQILI
                     IWKSVEKLLNNIKELYLRNGAAYSIRFWIKK"
     gene            21961..23132
                     /locus_tag="ACL3EZ_001102"
                     /pseudo
     CDS             21961..23132
                     /locus_tag="ACL3EZ_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017606.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
     gene            23527..24390
                     /locus_tag="ACL3EZ_001103"
     CDS             23527..24390
                     /locus_tag="ACL3EZ_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HGR0392682.1"
                     /translation="MIEKMELGEFYKELRLARKLKQSDVACAGLTASQLSKFELGQSM
                     LSADKLILAIQGINVTFDEFGHKLNNYQESPHMQIGRKVVDRFAHQDIAGLEQLLEEV
                     EQGQMAETYRRLNAIVIKNALHSLDKSYPLAEEDSEFLTTYLYAIESWTWFELYLFCN
                     TMPFLSNQDLIFLSTSLLEKSKEFKELVHNRLYMKSGFLNIISELMERKLFSYIPIFE
                     AELESMLRPYDVFEKVLWQFLKKMSIFLQTKGSNQKEIEHFIQSLQVLENPQLIALFE
                     LRLQQYKKLID"
     gene            24673..24873
                     /locus_tag="ACL3EZ_001104"
     CDS             24673..24873
                     /locus_tag="ACL3EZ_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000933472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide pheromone VP1"
                     /protein_id="HGR0392683.1"
                     /translation="MLNLQFAETMELTEAELEIVYGGEFGNNAVIPAGAWGGFGTPWS
                     ITNFWKKNFNDRPDFDSDRRRY"
     gene            24940..25605
                     /locus_tag="ACL3EZ_001105"
     CDS             24940..25605
                     /locus_tag="ACL3EZ_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysostaphin resistance A-like protein"
                     /protein_id="HGR0392684.1"
                     /translation="MKKIISHRYFIIVFLLVIADQKFSVLVLRSDLVTGLSDFAYYLS
                     DMMLNFLVVLFALIAMIWSGKWQKINSRKFKGSYLFYSFLALLAFVVWNFVTFFLFPP
                     TRNEISYQHAAPTFTGATAFLMYFFYPVIAGPIFEEIIHRGLVMTALEKGKKWGLDVL
                     GSAILFGVSHISNHGWVLTDFVFYMGGGLIFAVLFRMTKSIYWPIGLHIVYNGIGQLL
                     MLL"
     gene            25677..26903
                     /locus_tag="ACL3EZ_001106"
     CDS             25677..26903
                     /locus_tag="ACL3EZ_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HGR0392685.1"
                     /translation="MKVFLQNRDFRQLTINQWISTLGDTIFYLAFLNYVADASFAPLA
                     ILLITISETLPQVLQIFLGVLADFQHHRVLKYTVISFTKFLLYSIVSLSLSGQSFSLL
                     LVTFICMINLLSDTLSYFSGAMLTPIFIRIIGQDHLAEAIGFKQSTVSLVKTISNILG
                     GVLLGILSIQFISLLNALTFLIAFLGILFIKTDLLKVEKTISYQEGLSVKSFCQHLLQ
                     SSKLIWNMNKVLLVLFIISTSQAVINVTVPVSTLFLRNQPFLNLQTGQSLALLSTFEL
                     SALIVGSLVSGYLQHTISIKTTLYASLVIQLLLLVGFATVRFDWILIFSTLDAFFAGV
                     LSPRLQELVFKQIPEESMGAVQSSISAITVVLPSLFTISLVTIATSFGTLAVSFVLLL
                     FLLVAFVMLLNIRESI"
     gene            27309..29210
                     /locus_tag="ACL3EZ_001107"
     CDS             27309..29210
                     /locus_tag="ACL3EZ_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000584877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HGR0392686.1"
                     /translation="MIILQANKIERSFAGEVLFDNINLQVDERDRIALVGKNGAGKST
                     LLKILVGEEEPTSGEINKKKDISLSYLAQDSRFESENTIYDEMLHVFDDLRRTDKQLR
                     QMELEMGEKSGEDLDKLMSDYDRLSENFRQAGGFTYEADIRAILNGFKFDESMWQMKI
                     AELSGGQNTRLALAKMLLEKPNLLVLDEPTNHLDIETISWLENYLVNYSGALIIVSHD
                     RYFLDKVATITLDLTKYSLDRYVGNYSRFVELKEQKLATEAKNYEKQQKEIAALEDFV
                     NRNLVRASTTKRAQSRRKQLEKMERLDKPEAGKKAANMTFQSEKTSGNVVLTVENTAI
                     GYDGEVLSQPINLDLRKMNAVAIVGPNGIGKSTFIKSIVDQIPFIKGEKRFGANVEVG
                     YYDQTQSKLTPSNTVLDELWNDFKLTPEVEIRNRLGAFLFSGDDVKKSVGMLSGGEKA
                     RLLLAKLSMENNNFLILDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDRYFINRVAT
                     HVLELSENGSTLYLGDYDYYVEKKATAEMSQTEEASTSNQAKEASPVNDYQAQKESQK
                     EVRKLMRQIESLEAEIEELESQSQAISEQMLETNDADKLMELQAELDKISHRQEEAML
                     EWEELSDQV"
     gene            29213..30076
                     /locus_tag="ACL3EZ_001108"
     CDS             29213..30076
                     /locus_tag="ACL3EZ_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012291596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HGR0392687.1"
                     /translation="MEHLGKVFREFRTSGNYSLKEAAGESCSTSQLSRFELGESDLAV
                     SRFFEILDNIHVTIENFMDKARNFHNHEHVSMMAQIIPLYYSNDIAGFQKLQREQLEK
                     SKSSTTSLYFELNWILLQGLICQRDATYDMKQDDLDKVADYLFKTEEWTMYELILFGN
                     LYSFYDVDYVTRIGREVMEREEFYQEISRHKRLVLILALNCYQHCLEHSSFYNANYFE
                     AYTEKIIDKGIKLYERNVFHYLKGFALYQKGQCKEGCKQMQKAMHIFDVLGLPEQVAY
                     YQEHYEKFVKS"
     gene            30156..31334
                     /locus_tag="ACL3EZ_001109"
     CDS             30156..31334
                     /locus_tag="ACL3EZ_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001083019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HGR0392688.1"
                     /translation="MNRYAVQLISRGAINKMGNMLYDYGNSVWLASMGTIGQTVLGMY
                     QISELVTSILVNPFGGVISDRFSRRKILMTADLVCGILCLAISFIRNDSWMIGALIVA
                     NIVQAIAFAFSRTANKAIITEVVEKDEIVIYNSRLELVLQVVGVSSPVLSFLVLQFAS
                     LNMTLLLDSLTFFIAFVLVAFLPKEEAKVQEKKAFTGRDIFVDIKDGLHYIWHQQEIF
                     FLLLVASSVNFFFAAFEFLLPFSNQLYGSEGAYASILTMGAIGSIIGALLASKIKANI
                     YNLLILLALTGVGVFMMGLPLPTFLSFSGNLVCELFMTIFNIHFFTQVQTKVESEFLG
                     RVLSTIFTLAILFMPIAKGFMTVLPSVHLSSFLIIGSGVIILSCISFIYVRTHFEKLI
                     "
     gene            31427..33385
                     /gene="ligA"
                     /locus_tag="ACL3EZ_001110"
     CDS             31427..33385
                     /gene="ligA"
                     /locus_tag="ACL3EZ_001110"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003911 - DNA ligase (NAD+) activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HGR0392689.1"
                     /translation="MNKRMNELVALLNRYATEYYTSDNPSVADSEYDRLYRELVELET
                     AYPEQVLADSPTHRVGGKVLDGFEKYSHQYPLYSLQDAFSREELDAFDARVRKEVAHP
                     TYICELKIDGLSISLTYEKGILVAGVTRGDGSIGENITENLKRVKDIPLTLPEELDIT
                     VRGECYMPRASFDQVNQVRQENGEPEFANPRNAAAGTLRQLDTAVVAKRNLATFLYQE
                     ASPSTRDSQEKGLKYLEQLGFVVNPKRILAENIDEIWNFIQEVGQERENLPYDIDGVV
                     IKVNDLASQEELGFTVKAPKWAVAYKFPAEEKEAQLLSVDWTVGRTGVVTPTANLTPV
                     QLAGTTVSRATLHNVDYIAEKDIRKDDTVIVYKAGDIIPAVLRVVESKRVSEEKLDIP
                     TNCPSCNSDLLHFEDEVALRCINPRCPAQIMEGLIHFASRDAMNITGLGPSIVEKLFA
                     ANLVKDVADIYRLQEEDFLLLEGVKEKSAAKLYQAIQASKENSAEKLLFGLGIRHVGS
                     KVSQLLLQYFHSIENLSQADSEEVASIESLGGVIAKSLQTYFATEGSEILLRELKETG
                     VNLDYKGQTVVADAALSGLTVVLTGKLERLKRSEAKSKLESLGAKVTGSISKKTDLVV
                     VGADAGSKLQKAQELGIQVRDEAWLESL"
     gene            33497..35776
                     /gene="pulA"
                     /locus_tag="ACL3EZ_001111"
     CDS             33497..35776
                     /gene="pulA"
                     /locus_tag="ACL3EZ_001111"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051060 - pullulanase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I pullulanase"
                     /protein_id="HGR0392690.1"
                     /translation="MYNYPMRIHYHRKNGEYDTCSFVKSQDQRIDLLTYKEDYFGALF
                     SFEHPSSHVIESLNFVVHTGQTSKEYSIRFNHYPLLTEVWILEGDDRIYYSENPAIAS
                     PFYKNQNPFAFDKAINSASFDHHWGYQGELGCRVEDNQAHFSLWSPTATEVQVVVYES
                     AANDAPVWKTFEMKRGNSYSYNHKDNTIGVWSLDVEEDLVGKAYQYQVQFPHHQTLTR
                     DPYTIATSPDGKRSAILSHVEKQVENFEVKHGSEATWRLENPCKAVICEMHIRDLTKS
                     PTSGVDEHLRGTFLGAAQAGTVNQYGQSTAFDYIKKLGYNYVQLQPIADRHKEYDEDG
                     NVTYNWGYDPQNYNAPETSFSTNPDDPAQVIRDLKVMVQAYHDAGIGVIMDVVYNHTF
                     SVVDAPFQTTVPDYYYRMNPDGTFQNGTGVGNETASEHEMFRKYMIDSLLYWVQEYNI
                     DGFRFDLMGIHDVKTMQMIRQSLDEIDSNIILYGEGWDMGTGLAPYDKAKKDNAYQMP
                     NIGFFNDNQRDAVKGGEVYGAIKSGFVSGAATEPILAKAILGSRELGSYTHPNQVLNY
                     VEAHDNYNLHDLLATLHPDQSSEQIMRKVETATAMNLLMQGMAFMEIGQEFGRTKLVA
                     TGENGELTHDDRERAMNSYNAPDSVNQVNWNLINERQDSIEFIRQVIRLKTKTGAFSY
                     SSYDEIYHHVFVHSAIEHSGYLIYEVHGKEHLLVVVNAKSEPYQFENAGNLAMLVTNS
                     RSKEDNVLNDISLAVLSVL"
     gene            36321..37745
                     /locus_tag="ACL3EZ_001112"
     CDS             36321..37745
                     /locus_tag="ACL3EZ_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HGR0392691.1"
                     /translation="MTRYQNLVNGKWKSSEQEITIYSPINQEELGTVPAMTQTEADEA
                     MQAARAALPAWRALSAVERAAYLHKTAAILERDKEEIGTILAKEVAKGIKAAIGEVVR
                     TADLIRYAAEEGLRITGQAMEGGGFEAASKNKLAVVRREPVGIVLAIAPFNYPVNLSA
                     SKIAPALIAGNVVMFKPPTQGSISGLLLAKAFEEAGIPAGVFNTITGRGSEIGDYIIE
                     HKEVNFINFTGSTPIGERIGRLAGMRPIMLELGGKDAALVLEDADLEHAAKQIVAGAF
                     SYSGQRCTAIKRVIVLESVADKLATLLQEEVSKLTVGDPFDNADITPVIDNASADFIW
                     GLIEDAQEKEAQALTPIKREGNLLWPVLFDQVTKDMKVAWEEPFGPVLPIIRVASVEE
                     AIAFANESEFGLQSSVFTNDFKKAFEIAEKLEVGTVHINNKTQRGPDNFPFLGVKGSG
                     AGVQGIKYSIEAMTNVKSIVFDVK"
     gene            38228..40156
                     /gene="glgB"
                     /locus_tag="ACL3EZ_001113"
     CDS             38228..40156
                     /gene="glgB"
                     /locus_tag="ACL3EZ_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003844 - 1,4-alpha-glucan branching
                     enzyme activity [Evidence IEA];
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_function: GO:0043169 - cation binding [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0005978 - glycogen biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-alpha-glucan branching protein GlgB"
                     /protein_id="HGR0392692.1"
                     /translation="MDNREALKTFMTGENFYLQHYLGAHREELNGEHGYTFRVWAPNA
                     QAVHLVGDFTNWIENQIPMVRNDFGVWEVFTNMAQEGHIYKYHVTRQNGHQLMKIDPF
                     AVRYEARPGTGAILTELPEKKWKDGLWLARRKRWGFEERPVNIYEVHAGSWKRNSDGS
                     PYSFAQLKDELIPYLVEMNYTHIEFMPLMSHPLGLSWGYQLMGYFALEHAYGRPEEFQ
                     DFVEECHTHNIGVIVDWVPGHFTINDDALAYYDGTPTFEYQDHNKAHNHGWGALNFDL
                     GKNEVQSFLISCIKHWIDVYHLDGIRVDAVSNMLYLDYDNAPWTPNKDGGNLNYEGYY
                     FLQRLNEVIKLEYPDVMMIAEESSSATKITGMKEIGGLGFDYKWNMGWMNDILRFYEE
                     DPIYRKYDFNLVTFSFMYVFKENYLLPFSHDEVVHGKKSMMHKMWGDRYNQFAGLRNL
                     YTYQICHPGKKLLFMGSEYGQFLEWKSEEQLEWSNLEDPMNAKMKYFTSQLNQFYKDH
                     RCLWEIDTSYDGIEIIDADNRDQSVLSFIRKGKKGEMLVCIFNMVPVERKDFTIGLPV
                     AGIYEEVWNTELEEWGGVWKEHNQTVQTQEGLWKDYEQTLTFTLPAMGASVWKIKRRL
                     KSTKTVTNKNQKGVENEK"
     gene            40146..41288
                     /locus_tag="ACL3EZ_001114"
     CDS             40146..41288
                     /locus_tag="ACL3EZ_001114"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000787267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008878 - glucose-1-phosphate
                     adenylyltransferase activity [Evidence IEA];
                     GO_process: GO:0005978 - glycogen biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HGR0392693.1"
                     /translation="MKNEMLALILAGGQGTRLGKLTQSIAKPAVQFGGRYRIIDFALS
                     NCANSGIHNVGVVTQYQPLALNNHIGNGSSWGLDGINSGVSILQPYSASEGNRWFEGT
                     SHAIYQNIDYIDSVNPEYVLILSGDHIYKMDYDDMLQSHKDNNASLTVAVLDVPLKEA
                     SRFGIMNTDANNRIVEFEEKPAQPKSTKASMGIYIFDWQRLRNMLVAAEKSKVGMSDF
                     GKNVIPNYLESGESVYAYEFSGYWKDVGTIESLWEANMEYISPENALDSRNRQWKIYS
                     RNLISPPNFLGANAHVEDSLVVDGCFVDGTIKHSILSTGAQVREGAEVLDSVIMSGAI
                     IGQGAKIKRAIIGEGAIISDGVEIDGTDEVQVVGYNEVVGVATDED"
     gene            41278..42417
                     /gene="glgD"
                     /locus_tag="ACL3EZ_001115"
     CDS             41278..42417
                     /gene="glgD"
                     /locus_tag="ACL3EZ_001115"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008878 - glucose-1-phosphate
                     adenylyltransferase activity [Evidence IEA];
                     GO_process: GO:0005978 - glycogen biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HGR0392694.1"
                     /translation="MKIDKYSAILGNTVGFHDMSTLTDHRPVASLPFGGKYRLIDFPL
                     SSLANAGVRSVFGIFQQDNISSVFDHIRSGREWGLSTLLSHYYLGIYNTRVESSTVGK
                     EYYQQLLTYLKRSGSNQTVALNCDVLINIDLNQVFHLHSTTKEPITVVYKKLAKKDIS
                     EVNAILDVDETDHVLSHKLFDSKSTAETFNMSTDIFVVDTPWLIEHLEEEAKKEHPEK
                     LRYVLRDLAVKEGAFAYEYTGYLANIHSVKSYYQANIDMLESQKFYSLFSPNQKIYTK
                     VKNEEPTYYANTSKVSTSQFASGSIIEGQVANSVLSRNIHVHKDSLVKDSLLFPRVVI
                     GEGAQVEYAILDKGVEVELGVVIRGTAEHPVVVKKGAKVTEDIHS"
     gene            42414..43847
                     /gene="glgA"
                     /locus_tag="ACL3EZ_001116"
     CDS             42414..43847
                     /gene="glgA"
                     /locus_tag="ACL3EZ_001116"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004373 - glycogen (starch) synthase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HGR0392695.1"
                     /translation="MKILFVAAEGAPFSKTGGLGDVIGALPKSLVKAGHEVAVILPYY
                     DMVEAKFGNQIEDVLHFEVSVGWRRQYCGIKKTVLNGVTFYFIDNQYYFFRGHVYGDF
                     DDGERFAFFQLAAIEAMERIDFIPDLLHVHDYHTAMIPFLLKEKYCWIQAYEDIETVL
                     TIHNLEFQGQFSEGMLGDLFGVGLERYADGTLRWNNCLNWMKAGILYANRVSTVSPSY
                     AHEIMTSQFGCNLDQILKMESGKVSGIVNGIDADLYNPQTDALLDYHFNQEDLSGKAK
                     NKAKLQERVGLPVRADVPLVGIVSRLTRQKGFDVVVESLHHILQEDVQIVLLGTGDPA
                     FEGAFSWFAQIYPDKLSANITFDVKLAQEIYAACDLFLMPSRFEPCGLSQMMAMRYGT
                     LPLVHEVGGLRDTVRAFNPIEGSGTGFSFDNLSPYWLNWTFQTALDLYRNHPDIWRNL
                     QKQAMESDFSWDTACKSYLDLYHSLVN"
     gene            43906..44277
                     /locus_tag="ACL3EZ_001117"
     CDS             43906..44277
                     /locus_tag="ACL3EZ_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family phosphatase"
                     /protein_id="HGR0392696.1"
                     /translation="MSQVKGLCVLDVDGTLILEEVIDLLGREAGHEAEISQITSRAMR
                     GELVFESSLRKRVSLLEGLPILVFDNVFNSIHLSLNVPEFISILQKNGILVGLVSGGF
                     TPIVGEISKIPWYCLFHCQPA"
     gene            44222..44551
                     /locus_tag="ACL3EZ_001118"
     CDS             44222..44551
                     /locus_tag="ACL3EZ_001118"
                     /inference="COORDINATES: protein motif:HMM:NF019887.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase family protein"
                     /protein_id="HGR0392697.1"
                     /translation="MERLAKSLGIAYFTANQLEVKEGLLTGKLVGQIISPQVKKETLE
                     KWRKKLKLSKERTVAIGDGVNNLLMLKSAELGIAFCSKEMLKKEIPHHVDKRDFLEVL
                     PLIDCLE"
     gene            44560..45363
                     /locus_tag="ACL3EZ_001119"
     CDS             44560..45363
                     /locus_tag="ACL3EZ_001119"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008887 - glycerate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0031388 - organic acid phosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HGR0392698.1"
                     /translation="MKIVIAPDSFKESLTAQQVAEAIKRGFQQSIADVECLLCPVGDG
                     GEGTVDAIRHSLDLKEKWIQVTDPFGQKEAMRYFQKGELALFEVADLVGLGKIPLEKR
                     NPLQIQTCGIGELILHLISKGIKDIYIGVGGTASNDGGLGIAAGLCAFAQASIVSGID
                     TCLDLINFDKKVSDADLVVVGEGRLDSQSFAGKAPIGVAKRTPVGVPVIAICGSLAED
                     LPPLPFENIQAVFSILEKSEPLEDSLKNASLYLERTAANIGHLLNMCKI"
     gene            complement(45360..45806)
                     /locus_tag="ACL3EZ_001120"
     CDS             complement(45360..45806)
                     /locus_tag="ACL3EZ_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HGR0392699.1"
                     /translation="MTDLSKQLLEKAHGGLKINPDEQRRYLGTFEERVLGYVDIDTAN
                     SPQLEKGFLFILENLQEKAKPLFVKISPTIEFDKQVFYLKEAKETDSQATIVSEEHIT
                     SPFGLVIHSNAPVQVEEKDLRLAFPKLWEVKKEEPAKTSLWKKWFS"
     gene            45970..47274
                     /gene="eno"
                     /locus_tag="ACL3EZ_001121"
     CDS             45970..47274
                     /gene="eno"
                     /locus_tag="ACL3EZ_001121"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="surface-displayed alpha-enolase"
                     /protein_id="HGR0392700.1"
                     /translation="MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTG
                     EHEAVELRDGDKSRYGGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEIPLYSYLGGFNTKVLPTPMMNIINGGSHSDAPI
                     AFQEFMILPVGAPTFKEALRYGAEIFHALKKILKSRGLETAVGDEGGFAPRFEGTEDG
                     VETILAAIEAAGYVPGKDVFIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQID
                     YLEELVNKYPIITIEDGMDENDWDGWKALTERLGKKVQLVGDDFFVTNTDYLARGIQE
                     GAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQ
                     IKTGSLSRTDRIAKYNQLLRIEDQLGEVAEYRGLKSFYNLKK"
     gene            complement(47412..47858)
                     /locus_tag="ACL3EZ_001122"
     CDS             complement(47412..47858)
                     /locus_tag="ACL3EZ_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGR0392701.1"
                     /translation="MRKHGLISKSTSKGYYQVAIPFMRLFCLVLVSIDYINCLSETTD
                     KNWHKSDRIFVTNTGKPVHSSILSKSLQRANERLKKPIPKHLSPHIFRHTTISILSEN
                     KIPLKTITDRVGHSDSEVTTSIYTHVTKNMKDEAINVLDKVMKKIF"
     gene            complement(47758..47970)
                     /locus_tag="ACL3EZ_001123"
                     /pseudo
     CDS             complement(47758..47970)
                     /locus_tag="ACL3EZ_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(48056..48167)
                     /locus_tag="ACL3EZ_001124"
                     /pseudo
     CDS             complement(48056..48167)
                     /locus_tag="ACL3EZ_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT        14896 a         8239 c        10338 g        14694 t
ORIGIN      
        1 acgataaaat ttttattcat cagattattt gacacaagta ctttaatgaa gaggagaata
       61 ttttttcttt tcgcattgga tgttatagtt tacttatttt taggatatct tttagtgatt
      121 caaaaagcag gctatttgtt ttcggtttta cttctttttt ctaatttttc agttccattt
      181 atcaaagaaa aggaatacga attatttaaa aatagcaagt aatagaaata tggattaaat
      241 cttagaacgg cttaaaatca gacatgataa aggaaagcta tctaggtaac caagtactat
      301 aaacacagtc gaggatcact tgttaggatt acattttaat catgcttaat aagaatggag
      361 aattcctatg gggattgtat tactctgaag ttttgaatac cttagttctc gtgattttga
      421 gctattctag ctttagaatc cttcagaacg taaaatttta agcagtcaaa gacttagaat
      481 agcccgaaaa catttatttt atagcaattc taagattaga attgctcata tatatgtatt
      541 tgagctgctc gatagttagg atagctctat tctgagaaat ctgacctatc aatgcttcag
      601 aatagtattt cgcaaatggt ttttattgaa gaggtgattg ttttatgata gtctaaaata
      661 aaactgattt atggagtaaa tggagaatcg tcacatgaaa catttttttg caggaattgg
      721 tgagataaaa cttgttggct acttattgta tatatgtgta ggactagccc ctctttttca
      781 tatatatgtc ataggttcgg aactgagttt tgtgaaaata gtgttatcta ttttgggagt
      841 tatatttgta agtatgttaa ctattgctcg aatttatcgg acttttctat aaagaatagt
      901 ttggacttga actgtatcta aaaacagagg ttggtcgatt atcagcctct ttcttgtcgt
      961 tgaaaagagt gagatatatt gacttttgaa aaaaatgtca taattgagtt gggataaacc
     1021 taaaagtaat atagtagatt gaatctggaa tagtccgtta tgactgttaa aatatttcta
     1081 gaaattaatt tgactttcct aatcgatttg ttcacatctt gtttcaatct actatacttt
     1141 ctcgttaaac cgttcggcaa ttcatggtga catggacaca tagtagtaag cacactatgt
     1201 ggcttggcag agctaaaaac tgttcccttg cgataagcct aataagcaca acatagggag
     1261 ttagagaagc cgactctaat caatcacttt gggcagtagt gagaactgcc ccgtgctttt
     1321 tattttgaga aaatatggag tttgtcgttg aaattacttg attgtatttt ggattatcaa
     1381 gaaagattca atggaaaaac atgtcaagta tcaacgaatt ataagtattt agagactttc
     1441 aaagtgaatt tttgcttgac tgatttacat catttatttg gcttacacaa aatcacacga
     1501 gattttgcta gtcatacgat atctgttatt caaactggtg tttttatttt ggaagatttt
     1561 agaaatatcc tattgtacaa tgatgtaatc gaaaggatat ctttatatga gtttatcggc
     1621 gatatcttct attctaagct aacaagttat tgcatcgtag ctaaggattt atctaaaaat
     1681 actatgaaat tggacgtcat attttttgag gataaaaata aaagatccgc agttttaggt
     1741 ttacgaagag ataaaagcgg agtatttaaa ccagttactc tacattttac aagcgctaag
     1801 aaatatgcta aagttcgtaa aacaaatgtg aaagaaatga aatggctata aagattgtcc
     1861 gcagccttaa gcttgcgttt tttgttgttt aacgaaatta aaaaacaagc tctctcatcg
     1921 gaaatgtttt tataggaatg aaggaagatg atgctatgtt taaaaagaga atcgaaaagg
     1981 gcaaaagtag tgtctttatc tttttggagt agaagcttat gatatagaaa tttgtaataa
     2041 aaatgtaata taaaacattt gacaaatatt tacgggggga gtatacttaa tataagtata
     2101 gtctaaaaat gactatcaga aaagaggtaa atttagatga ataagaaaaa aatgatttta
     2161 acaagtctag ccagcgtcgc tatcttaggg gctggttttg ttacgtctca gcctactttt
     2221 gtaagagcag aagaagcccc cgtagctagt cagtctaaag ctgagaaaga ctatgatgca
     2281 gcagtgaaaa aatctgaagc tgctaagaag gcttacgaag aagctaaaaa gaaagcagaa
     2341 gacgctcaga aaaaatatga tgaggatcag aagaaaactg aagagaaagc cgaaaatgaa
     2401 aaaaaggcag cagcagactt gaacgaagcc acagaagtgc atcaaaaagc atatgtaagg
     2461 tattttgaaa ttcaacgagc aaaagattca aaaaaatata aaaataatcg tgataagtac
     2521 aataaagatc tcgctgaagc agatcaaaaa ataaaggata caaaaacagt attagatgaa
     2581 aagcaatcta aattttatgc tgtaagagca gttgtagttc ctgaagcaaa ggagttagct
     2641 gttactaaac aaaaagcgga agaaactaaa aaaggcgccg aagtagctaa ggagaaatat
     2701 gataaggcag ctcaagaggt agaagtagcg aagaaagaag tagaggcaga agaagctgag
     2761 ttggataaaa aagttgctga acttcaaaat aaagttgctg atttagaaaa agaaatagct
     2821 gatgctgaaa aaacggtagc agatttagaa aaagaagttg ctaaacttga aaaagatgta
     2881 gaaggtttca aagaatcaga tggtgaatat gccaaattct accttgaagc tgctgaaaaa
     2941 gacctagcta ctaaaaaagc taaattagca gaagctaaaa ttaaagctgc tactaaaaaa
     3001 gctgaattag aacctgaatt agaaaaagca gaagctgaac ttgaaaacct attatctaca
     3061 ctagaccctg aaggtaagac tcaggatgaa ttagataaag aagctgctga agctgagttg
     3121 aataaaaaag ttgaagctct tcaaaaccaa gttgctgaat tagaagaaga actttcaaaa
     3181 cttgaagata atcttaaaga tgctgaaaca aacaacgttg aagactacat taaagaaggt
     3241 ttagaagaag ctatcgcgac taaacaagct gagttagaaa aaactcaaaa agagttagat
     3301 gcagctctta atgagttagg ccctgatgga gatgaagaag aaactccagc cccagaagca
     3361 ccagctgaac aaccaaaacc agaaaaacca gctgaagaaa ctccagctcc tgcaccaaaa
     3421 ccagagaagt cagcagatca acaagctgaa gaagactatg ctcgtagatc agaagaagaa
     3481 tataaccgct tgactcaaca gcaaccgcca aaagcagaaa aaccagctcc agctcctgca
     3541 ccaaaaccag agcaaccagc tcccgcacca aaaacgggct ggaaacaaga aaacggtatg
     3601 tggtacttct acaatactga tggttcaatg gctacaggtt ggctacaaaa caacggttca
     3661 tggtactacc tcaacagcaa tggtgctatg gctacaggat ggctccaata caatggttca
     3721 tggtattacc taaacgctaa cggcgctatg gcaacaggtt gggctaaagt caacggttca
     3781 tggtactacc tcaacgctaa tggtgctatg gctacaggat ggctccaata caacgattca
     3841 tggtattacc taaacgctaa cggcgctatg gcaacaggtt gggctaaagt caatggttca
     3901 tggtactacc tcaacgctaa tggtgctatg gcaacaggtt gggctaaagt caacggttca
     3961 tggtactacc taaacgctaa cggtgctatg gcaacaggtt gggctaaagt caacggttca
     4021 tggtactacc tcaacgctaa cggttcaatg gcaacaggtt gggtgaaaga tggagatacc
     4081 tggtactatc ttgaagcatc aggtgctatg aaagcaagcc aatggttcaa agtatcagat
     4141 aaatggtact atgtcaatgg tttaggtgcc cttgcagtca acacaactgt agatggctat
     4201 aaagtcaatg ccaatggtga atgggtttaa gccgattaaa ttaaatcatg ttaagaacat
     4261 ttgacatttt aattttgaaa caaagataag gttcgattga atagatttat gttcgtattc
     4321 tttaggtacc tatcttatga tttcaggaaa tgtcattaaa aaaacgactc cttttctcta
     4381 acttgaaaaa tagattagag aaaatgggtt gttttattta ttatagttat ttgaatgaag
     4441 ataagaagaa ggtatactca catcattcac ataatctgta tattgactat aagttttaaa
     4501 aaacaatttt taagctcttc cttgtcttct ctaaccaagc gtgttataat gaatactgct
     4561 caagcgacct tcaatcgtga agcacacacg accttcaatc gtgaataaac gaatagatgg
     4621 gagacttacc atgagtgata actctaaaac acgtgttgtc gtggggatga gtggtggtgt
     4681 tgattcgtcg gtgacggctc ttttgctcaa ggagcagggc tacgatgtga tcggtatctt
     4741 catgaagaac tgggatgaca cagatgaaaa cggcgtctgt acggcgaccg aagattacaa
     4801 ggatgtggtt gcggtggcag accagattgg cattccctac tactctgtca attttgaaaa
     4861 agagtactgg gaccgcgttt ttgagtattt cctagcggaa taccgtgcag ggcgcacgcc
     4921 aaatccggac gttatgtgca acaaggaaat caagttcaag gcctttttgg actatgccat
     4981 gaccttgggg gcagactatg tagcgactgg gcactatgct cgagtggcgc gtgatgagga
     5041 tggcactgtt cacatgcttc gtggcgtgga caatggcaag gaccagacct atttcctcag
     5101 ccaactttcg caagaacaac tccaaaaaac catgttccct ctgggacatt tggaaaagcc
     5161 tgaagtacgc agactagcag aagaagcagg cctttcgact gctaagaaga aagactcgac
     5221 agggatttgc tttatcggag aaaagaactt taaaaacttt ctcagcaact acctgccagc
     5281 tcagcctggt cgcatgatga ctgtggatgg tcgcgatatg ggcgagcatg caggtcttat
     5341 gtactataca atcggtcagc gtggcggact cggtatcggt gggcaacacg gcggtgacaa
     5401 tgccccttgg ttcgttgtcg gaaaagatct aagcaagaat attctctatg taggacaagg
     5461 attctaccat gattcgctca tgtcaactag cctagaagcc agtcaagtcc actttactcg
     5521 tgaaatgcca gaagagttta cgctagaatg tacggctaaa ttccgttacc gtcagcctga
     5581 ctctaaggtg accgtccatg tcaaaggaga caaggcagaa gttatctttg cggaaccaca
     5641 acgcgcgatt acaccaggac aggcagttgt cttttacgat ggcgaagagt gtctaggtgg
     5701 cggtttgatt gacaatgctt accgcgatgg acaagtttgt cagtacattt agattgacaa
     5761 attttctcaa tttgctacaa taataacagc aatagaaatg atggtcaaag ctcatggatg
     5821 ttgcaggctt ttttgtcctg cacttctttg tagttttgac tgtttttgtg tcgtttaagg
     5881 gaaaggacaa gaatgactca acaagacttt cggacaaaag tagacaataa ggtttttggt
     5941 gttcgggcga cagctttgat tcttcaaaat cgcaagcttc tagtcaccaa agacaagggc
     6001 aagtattaca ttatcggcgg tgcgattcaa gttaacgaaa aaacggaaga cgcggtagtc
     6061 cgtgaagtga aggaagaact gggtgttaaa tctcaagctg ggcagctagc ttttgtggtt
     6121 gaaaatcgtt ttgaagtgga cggcgtttcc tatcacaata tcgagtttca ttatctggtg
     6181 gatttgcttg aagatgcccc gttgaccatg caggaagatg agaaaaggca gccctgtgag
     6241 tggattgact tggataagct tgaggatatc cagctagttc cagccttttt aaaaacggcc
     6301 ctaccagatt gggaaggcca actaagacac attcatcttg aggaatagga gagaaacatg
     6361 acttatcatt ttactgaaga atacgatatt attgtaattg gtgcgggaca cgctggggtt
     6421 gaggcttcct tggccgctag ccgtatgggc tgtaaggtcc tgcttgcgac catcaatatt
     6481 gaaatgctgg ctttcatgcc ttgtaatccc tctatcggtg gttctgccaa ggggattgtc
     6541 gtgcgtgaag tcgatgccct cggtggcgag atggccaaaa ccattgacaa gacttacatc
     6601 cagatgaaga tgctaaacac agggaagggg ccagctgtcc gtgcccttcg tgcgcaggct
     6661 gacaaggaac tttactctaa ggagatgcgc aagacggttg aaaaccaaga aaatctgacc
     6721 cttcgtcaaa ccatgattga tgagattttg gtggaagatg gcaaggttgt cggtgtgcgt
     6781 acagccaccc atcaagaata tgctgctaag gctgttattg tgacgacagg gactgctctc
     6841 cgtggggaaa ttatcatcgg agacctcaag tactcatcag gtcctaacca cagcttggct
     6901 tctattaacc tagctgacaa tctcaaggaa ctgggcctcg aaatcggtcg tttcaagaca
     6961 ggaacccctc cacgtgtcaa ggcttcttct atcaattacg atgtgacaga aatccaacca
     7021 ggagatgaag cacctaatca cttctcatac acttcacgtg atgaggatta tgtcaaggac
     7081 caagtgccat gctggttgac ctacaccaat ggtaccagtc atgagattat ccaaaacaac
     7141 ctccaccgtg cgcctatgtt tacaggtgtg gtcaagggag tgggacctcg ttactgtcca
     7201 tcgattgagg acaagattgt gcgctttgcg gacaaggaac gtcaccaact cttccttgag
     7261 ccagaaggac gcaatacaga ggaggtctat gtccaaggac tttcaaccag tctgcctgag
     7321 gatgtccaac gtgacttggt tcattccatc aaaggtctgg aaaatgcaga gatgatgcga
     7381 acaggttatg ctattgagta tgacatgatc ttgcctcacc agttgcgtgc gactttggaa
     7441 accaagaaaa tctcaggact tttcactgct ggtcagacaa atggaacatc aggttacgaa
     7501 gaggcagcag gccaagggat tatcgcaggg atcaatgcgg ctctgaaaat ccaagataag
     7561 cctgagttga ttttgaagcg tagtgacggt tacattgggg tcatgattga tgatttggtg
     7621 accaagggaa ccatcgaacc ctaccgtctc ttgaccagtc gtgctgaata ccgtctcatt
     7681 ctccgtcatg acaatgctga tatgcgcttg actgagatgg gacgcgagat tggccttgtg
     7741 gatgatgaac gctgggctcg ttttgaaatc aagaaaaatc aatttgataa tgagatgaaa
     7801 cgcctagaca gtatcaaact caagccagtc aaggaaacca atgctaaggt tgaggagatg
     7861 ggcttcaaac ccttgacaga tgcagtgaca gccaaggaat tccttcgccg tccagaagtt
     7921 tcttaccaag atgtggtagc cttcatcgga ccagctgcag aggatttgga tgataagatt
     7981 atcgaattga ttgaaacaga aatcaagtac gaaggctata tttcaaaagc catggatcag
     8041 gttgccaaga tgaaacgtat ggaagaaaaa cgcattccag ccaatattga ctgggatgac
     8101 atcgattcta ttgcgacgga agctcgtcag aagttcaaac tcatcaatcc agaaaccatc
     8161 ggccaagcca gccgtatttc gggggtaaac ccagcagata tttctatttt gatggtgtat
     8221 ctggaaggta aaaatcgtag tatttctaaa actcttcaaa aatcaaaatg atacgtcgtc
     8281 ggcttcttac gaatgagttc aaagcttggc tttgattcat ctccagcctc ccatagtttc
     8341 ccgaactatg ggagctaact caagttatgc attttcctag ccttctggtc tgattttcat
     8401 tgagttttaa tctcaaaaga aagcatagag aaaaacagct ccgaagacgg ggctgttttg
     8461 ttgacttgta ctcaatgaaa atcaaagagc aaactaggaa gctagccgta ggttgctcaa
     8521 agcactgctt tgaggttgta gatagaactg acgaagtcag ctcaaaacac cgttttgagg
     8581 ttgtggatag aactgacgaa gtcagtaaca tatatacggc aaggcgaagc tgacgtggtt
     8641 tgaagagtat tattcttcat ctggtgtgag gatcatcggg atgatgatcg gttcacgttc
     8701 ggtattttca tagaggaagg ggcgaatagc gttgacaatg gcaccattga cagattgcac
     8761 gctagcatcc ttatttttca gtgcgatacg aatggcattg aagaggatac gctggctttg
     8821 gcgaatcaag tcgccagact ctctcatgta gacaaagcct cggctgagga tgtctggacc
     8881 agatagaatc atctgcgatt tgaagtcaac agttgcgact gccagaacga caccgtcttc
     8941 agatagatcg cgacgatctt tgaggacagc tgcgccaatt tcaccgatac gatttccatc
     9001 gacatagata tcttgggcgt tgaaatgacc tgcgatacga gctgagtcag cagtaagggc
     9061 aagcacatcg ccattgctca tgataaagat attgtccttc tcaacaccag tatccactgc
     9121 tagttcagcg tggacttttt gcatgcggta ttcaccgtgg acaggcatga agtattttgg
     9181 cttaatcaag cagagcatga gtttttgctc ttgctgacca ccgtgtccag atgtatggat
     9241 attgttcact ttaccgtgga taacttcgac accagcttca gaaatgatgt taatcagctt
     9301 gttgacgcta gtagtgtttc cagggatggg actagaagag aagataacgg tatcacctgg
     9361 ttgtaattgt acttgacggt gggttccgtt ggcgatacga gagagggctg ccataggctc
     9421 accctgacta cctgtacaga ggataagaac ttctcctgca ggataatctt tgatttcatt
     9481 tggctcgata aaggttccct taggagcttt gatgtagcca agatcgattc cgttgacaat
     9541 ggccttttcc atagaacgac caaagaccgc aatcttgcgt ccagtcttaa cagcagcttc
     9601 tgttgcctgc tggagacgga agatatttga ggcaaaggat gcaaagatga tacgtccttc
     9661 aataccttgg ataatcttca taatggactg accaacgact ttttcagagt tggtaaaggt
     9721 tggtacttcc gcatttgtcg agtcagacag gagacagagc acaccttctt caccaagcgc
     9781 agccatacga tgcaagtccg caggttctcc aactggagta aagtcgaact taaagtcccc
     9841 cgtacagacg attttccctt gaggagtatg aatgacaatc cccaaaggct ctggaataga
     9901 gtgagtcgtt ctaaagaaag ttgccttgag atttttaaag gtcaactcgg tgttgtggtt
     9961 gatttcgtaa agtttggcgt tgcgcaagag gccgtgttct tcgagtttcc cacggatcaa
    10021 agccaaggca agcggtccag cgtagatagg gacatttgct tgcttgagta ggaacggaat
    10081 cccaccaatg tggtcctcgt gtccgtgtgt gattaaaaca gccttgacgc ggtcgatatt
    10141 gtccacgatg taagagtagt caggaatgac atagtcgata ccaagcaagt catcttctgg
    10201 gaatttaatc ccagcatcga cgatgataat ctcgtcttgg tattcaattc cgtaagtgtt
    10261 tttcccgatt tctcctagac caccgatggc aaaaacgccg acttcttcag gtttaagagt
    10321 gtaggccata ttagaactcc gtaatttcga aggcgccagt ttctttttcg taatcgagca
    10381 atttgtcaga caagagttcg atatattcga tattgtactc tgggcgattt tcttcgacaa
    10441 gttggcgagc agtgatacgg ccctcaagtt ctgagctggc atcgatgtct aggtaaagcg
    10501 cgcgtgttgt ttcacggcgt gggctacgtt cttttgtttc ttgataaaaa actttgtaaa
    10561 tcatatagtt cctttctatt tacaggtcag cttattccaa acttttagca gatatttgct
    10621 tgatttcatt ccattttgtg tctagattga ccttgattcg ttacaattat ttcaattata
    10681 ccacaaaatg aaaaattagt aaaagacgga aacgagaaag ttagggggca atttctttgg
    10741 taagcgttta caaaaataaa gaaaatgtat tatgttgata acggaagtga aatttattgc
    10801 ttgtcataat tccatataga ttttaagtca aggaggttgc cctatgtata acttatttgc
    10861 ttttgctatc ggagttcgtt tgttagcttt tatcgttttt gttgcttgcg tttatggagg
    10921 aaatcttcca tttgccaaac tggaacgatg acaaaccaag ttcttgtgga aaattacctt
    10981 tgtgactctc tactcgcttt ttctcctcct cgtgccctat gtcgtttggt ttgtatttta
    11041 ctttggatta aatgcttaga tgccctgctt atgctggggt tttttgtttg gggatgtaga
    11101 gatagtagat ttacgacacg aaaattccac cccatctatc aagatgaggt ggtctttgca
    11161 tttttctaaa atgacatgac aatggaattt tcaaagctta ttatttttat gggagtcatt
    11221 gttctgctca aaaatagagt tgaagcataa aaataaaaca atacaaacag ataaatcgaa
    11281 tggtaaaggg atagtagtaa tgttcaaatc attgagaatg ctgagcaaac tgtaagagat
    11341 gaagacaata aaatttatcc ttctaaaaat gtgtttctta tctagcatga cttaccaaac
    11401 tttttacgaa ggtcttttcc aatggtataa cctgccataa ataaagcgat accaacacct
    11461 acaccaaagc cacccttgat ttcttgcaat tccttattag aaatttcacg atagttgttc
    11521 aaatttttca tcatattaat ctcctcctaa aaaataacca gctgccaaac cagaacctat
    11581 aagtgctgtt ccacctgcaa tagccttcca agatactgct actccaaaga taaccaaggg
    11641 agcgagaccg ccatcaatat ctgataattc attttcagat aaggataaaa attgattgtc
    11701 aagaatgtca aaatttgtca ttgaactttc ctcctttttt cttgttcact tttatattcg
    11761 gaaaagaaaa ggaaaagtga gcattttttt aaattatttt tagttaagtg agggcactct
    11821 tgtctggggg caaagaaaat tcccatgtgc cagcttttgt agtataatag taagcagaca
    11881 aaaagatagg aatgtgttat gaaagtatta gcttttgata cgtccagcaa ggctctttct
    11941 ctcgctattt tagaggacaa gcaggttctt gccgagacga cgattaatat taagaaaaat
    12001 cacagtatta ctcttatgcc tgccatagat tttttgatgg caagtttgga ttggacaccc
    12061 aaggatttgg accgaatcgt ggtagctgaa gggccgggta gctatacagg cttgcgaatt
    12121 gcggtagcaa ctgccaagac cttggctcat accctgaaca ttgagttagt tgggatgtct
    12181 agtctattgg ctctggtgcc acgccaaaaa gaaggcttgg tggttcctat catggatgcg
    12241 cgtcgcaaca atgtctatgc aggcttttat gaaaatgcca agccagtctt gccagaagcg
    12301 catctgtctt ttgcggaagt gctagagcag gtcaaggatg ctgagcaggt gacctttgtc
    12361 ggagaagttg gagcctttgt ggaacagatc caagaacaac taccacaagc cagctaccaa
    12421 gaaaccttgc caaatgcagc taatctagct ctttgggctt gggacaaaga agcagactcc
    12481 ttgcacgact ttgtgccaaa ttacctcaag cgtgtcgagg ctgaggaaaa ctggctcaag
    12541 aaccataccg agtctggcga gtcttacatt aaacgcctat gatagaaatc aaacgaatcc
    12601 aacagcagcc tgatctagct aaagccatct acgctgttat gatagctgtt tacccagtca
    12661 gtccttggac gctggaacaa atccaagctg acctgttcca agaccagact tggtatgctc
    12721 tggcttatga tggggcagaa gtgattggct ttctagctgt tcaggagact ctctttgaag
    12781 cagaagtcct gcaaatcgct gtcaaaggag cctatcaggg taagggcatt gcgtcagcct
    12841 tgtttgctca attgccgaca gataaggaga ttttcctcga agtcagaaag tcaaatcaac
    12901 gagcgcaagc attttacaag aaagaaaaaa tggcggtcat cgctgatcga aaggcctact
    12961 accatgaccc agtcgaggac gccattatca tgaagagaga aatagatgaa ggatagatat
    13021 attttagcat ttgagacatc ctgtgatgag accagtgtcg ccgtcttgaa aaacgacgat
    13081 gagctcttgt ccaatgtcat tgctagtcaa attgagagtc acaaacgttt tggtggcgta
    13141 gtgcccgaag tagccagtcg tcaccatgtc gaggtcatta cagcctgtat cgaggaggca
    13201 ttggcagaag cagggattac cgaagaggat gtgacagctg ttgcggttac ctacggacca
    13261 ggcttggtcg gagccttgct agttggtttg tcagctgcca aggcctttgc ttgggctcac
    13321 ggacttccac tgattcctgt taatcacatg gctgggcacc tcatggcagc tcagagtgtg
    13381 gagcctttgg agtttccctt gctagccctc ttggttagcg gtgggcacac agagttggtc
    13441 tatgtttcgg aggcaggaga ttacaagatt gttggggaga cacgagacga tgcagttggg
    13501 gaggcttatg acaaggtcgg tcgtgtcatg ggcttgacct atcctgcagg tcgtgagatt
    13561 gacgagctgg ctcatcaggg gcaggatatt tatgatttcc cccgtgccat gattaaggaa
    13621 gataatctgg agttctcctt ctcaggtttg aaatctgcct ttatcaatct tcatcacaat
    13681 gccgagcaaa agggagaaag cctgtctaca gaagatttgt gtgcttcctt ccaagcagca
    13741 gttatggaca ttctcatggc aaaaaccaag aaggctttgg agaaatatcc tgttaaaacc
    13801 ctagttgtgg caggtggtgt ggcagccaat aaaggtctca gagaacgcct agcagccgaa
    13861 atcacagatg tcaaggttat catcccccct ctgcgactct gcggagacaa tgcaggtatg
    13921 attgcctatg ccagcgtcag cgagtggaac aaagaaaact tcgcaggctg ggacctcaat
    13981 gccaaaccaa gtcttgcctt tgataccatg gaataaagag tggctctttg tcaagtgtag
    14041 tgggtaggcg aaaagctaca atctggagag tacgaaattc gtactctctt ttttgatgtt
    14101 caaagtcatc aaaatccgtt ttttaaaatt gttaaagttc cggaaaccaa aggctttgcg
    14161 cttgataacc ttaatcaaat tattggtcgc ttcaagttta gcgttggaat aaggcagctt
    14221 aagtgcgttg ataatcttat ctctatccct taaaaaagtc caaaagaccg tttgaaaaag
    14281 cggatgaacc gttggcagtt cttgctcaat caatccaaag aaatggtcgg cattcttctc
    14341 ttgaaaatga aagagcagga gttgatagag ttcgtagtga acctgtaatc cctcagagta
    14401 agaaagcagc ttatctcgta cttcccgatg ggttaagtgc attcgaaacg tgggctgata
    14461 gaatcgtttc tgacagagct tgaagctatc ctggtgtagt aaatcagtcc agtggactga
    14521 tttagcccga gcctagaaac gaaaaagcga gggttccaaa agcgcttgag cgcccgatac
    14581 tccaaggatt ttcggtcaaa ttggttcatg atttggattc gtactcggtt catagctcgg
    14641 ctcagatgtt ggacaatgtg gaagcggtca agaacaatct tcgcctttgg aaagagttgc
    14701 ttagcgagcc gataataagg gctgtacatg tccatggtga tgacctcgac cagctcccga
    14761 acctctctct gatagcgttg gaaatggttt cgaatcaccg catgagttcg cccgtctaaa
    14821 attgcgagga tggatttgga ctcaaaatct tgggcaatga agctcatttt gctctttttg
    14881 aagctatact catcccaact cataactttt ggcaacttgg tccaatcggt ttcaaactta
    14941 aattccctca gttttcggat gacggtggaa gttgagaccg ccaatctgtg ggcaatctca
    15001 gtcatagact gcttttcaag gaggagctga gcgatttttt gtctcaccat gttggaaatc
    15061 tggcaatttt tcttgacaat ggatgtttga gaaacgacca ccttaaggca attcttgcac
    15121 tgaaagcggc gctttttgag atgtagtacc gtgggtaaac cctgacagtc gagaagcgga
    15181 attttagagg ctttctggaa gtcgtatttg atcatcttcc cttgacaatg aggacaagga
    15241 ggagcggggg aatccaactt tgcctgaacg actagatggg tttggtattt cagaacagac
    15301 aagattttga tatttttgtc tttcaatccg agcaaatctg tggtattctt aagttgttcc
    15361 atatgaaccc tttctaatga gttggttaga cgcttttcat tataggtcat atggggcttt
    15421 ttttctacaa gaaacgaccc tataattcct ggggtgggat tacccactac agaaattata
    15481 gagccaaaac attccaaagt cttgtctgac tctggaatgt tttctgttca cagttgtttt
    15541 gtaactgcct aataagtaac cgcgctataa cgaggtatct accgagattg tcaattctcc
    15601 agtatactgt tataaaaaac aaaactggag gattttttta tgtcccccca tcgtcccatc
    15661 gactgttccg tagctgccca ataacggagt atagtcggct gaaacaagaa taggacaaaa
    15721 gtgcctcaag aaaagcatcg taatttgaca atattattct gagatgtttt tgatgtaagc
    15781 ccatattttc tcaatgggat tatactcggg tgaataggta ggaagtggta acagtctatg
    15841 ccctgctcct tacacatgtt cattctgtga aaccttgcat tgtccataat gataagggat
    15901 ggtgtatcta aagtaggtag taagaatttt tggaagcaag cttcgaaaaa gtcactcgtc
    15961 atcgtatctt tataggtcat cggagccata gtatattgaa acaaaaaagg gcattagtac
    16021 ttctataaca gtatcgcaat ctctggtgtg cgttgtctcg atcttaattc aaataattat
    16081 atcttcttcc agagagacta actgcctgct caaggctcga tcatattcga gataaaaata
    16141 ggtctcaacc cctgtctcat aaatataaat aggagtcagg tagcttaagt gattcaattc
    16201 tttaaggaac cgatttactt tttctgggtc ttgttcgcag taggtacagc tcttttttag
    16261 actatatccc atagccttta gagcgtaatg aatagttgtt ggaggacagt tgaattcagc
    16321 agctatttca gtcaaataag catcgggatg agtttcaata tagatcttta atttatctct
    16381 atcaactttt tcaattaata gtggaagttt tcttaaagtt agtgtgttga aacgttttta
    16441 tacagtgcta aaatttgaag tgtagtgcag atgtatttgt aatagtatta tagcaattct
    16501 ttggagaagg tcgagacaag agaaaatagg tatctttgag atataagcat gatttactat
    16561 aaaattattg agttattcat aaaaatttct ctatcaaata tcataatgcg tcgtttaagg
    16621 agatggttac aatgcaatat agttgtggaa aaataaatat taatatccct gatggatatg
    16681 gagacattaa ggatatagtg ttttcggctc atattatagt taggtataat aatggacatt
    16741 gtggaggtat agatccgcat ataattggac tttgtaaaaa gcagatcaga aggatgtctc
    16801 tatatcctat tttgataatc gtatctagag attcaaaggt tattgatgat tataaaaatt
    16861 tagatattgc ctatgttgat tgtactcaat gttcaaataa ttttgaaact gccttacacg
    16921 ttaaaaatat tttaaaatta ttaaaaatcc aacttataca ctgtcatggc tactcaacta
    16981 attatttttt atatatgtta aaaaaacttg acaagaatgg atttggaaag gttaagacag
    17041 tgataacatg ccatggatgg gttgaatata acttaaaaaa gaaattcttg acttattttg
    17101 atttttggac atattctatg ggagatgctt ttatttgtgt atctgaaact atgaaaaaaa
    17161 gattggagag tataataaaa aaataagaag atagttgcaa taaataacgg aattaatgta
    17221 tcaaatagcg atttagatgt agtaggtgtt caagacttta aaaaagaatt ttgtattcca
    17281 aataacaaaa aaatcatttg ttatgttgga aggttggatc cagaaaaaag gccggataga
    17341 ttccttgaat ttgcagaaaa attattttta gtcagagaag atgtgatttt tattatggct
    17401 ggaaatggta gtatgtgggc tgctttgaaa gaaaaaattt gccatttgaa atgtagagat
    17461 aatttcaggt tacttggtga aatctatcca gctactatag tttaccaaat atcggattta
    17521 ttgtatattc cttctgatac agaaggaata cctatgtgtg ttttagagtc aatgtcacaa
    17581 ggaactccgg ttttagctag taatgttggc gggttaagtg aaattattga acataggatt
    17641 gatggatttt tatttgagaa ggaagatgtt gagggagtgt gtgcttgtgc taatttttta
    17701 ctcaatgatt ctgagtattt gaaatatata ggtgagaata gtaaatcaaa aataagaaaa
    17761 catttttctg tgcaaaaaat gtttgtagaa accatgagag tatatgatga attattagag
    17821 aagagtagtc atggatagga atatagatca agaattagta agtattataa taccaacaca
    17881 taataggtat gaatctctga ttagagctgt gaaaagttgt ttacatcaaa gttataaaaa
    17941 tatcgaagtt ataattattg atgataatta tagtaatgta aatttaagaa ataaaattat
    18001 ccatcaattt ggctatacca atcatagaat taagttaatt ttaagtaatg aagatttagg
    18061 tgcaactaat gccagaaaca taggtatcaa aaattctaga ggtaagtata tatcattttt
    18121 agacgatgat gatgaatata tgtcagatcg aattttaaag ttgatggctt gttttaaaaa
    18181 gagtagaatg aagaatttag ctttagttta tagttatgga ataataattt atccaaatgg
    18241 tacacgagaa gaggagaaga ccgattttgt tggaaatccc ttgtttgttc aaatggttca
    18301 caatatagca ggtacgtcat tttggttgtg taaaaaagag gtgctagaat taattaatgg
    18361 ttttgagaaa atagattcac atcaggacgg tgttgtttta ttaaaactac ttgctcaagg
    18421 ataccaaatt gatatagtgc gagaattctt ggtgaattac tacgctcaca gtaaagaaaa
    18481 cggtatcact ggagtgacac aaaaaacaat taatgcagat gaagaatatt ataattactg
    18541 taggaaatat tttaatttat tgagtttcaa cgagagaata ttggttacaa agaaatatta
    18601 ttctttaaac ataaagcggt tactattaat aggagacaaa tgcaaggctt taaaagtaat
    18661 caagaaggca agagaagaaa aaatttttaa cgaatttctt tttttgaaat atatgttatt
    18721 atatcatttt ggttttttct attgtatata tgacaactat gttcaattaa aatttagaaa
    18781 gtgagaaact attgtgtata ctattataaa atcaaatata aaaaaattta gtttattaac
    18841 gatatttatt gttgctggtc aattattgct aatttatgca gcaactatta atgctctggt
    18901 gttgaatgaa ttaattgcga tgaatttaga gcggtttttg aaattgtcaa tctaccaaat
    18961 gattgtctgg tgtgggataa tattccttga ctgggtagtg aaaaattatc aggttgaagt
    19021 gatccaagag tttaatctag agattcgaaa tagagttgcc acagacatct ctaactctac
    19081 ctatcaagaa tttcatagta aatcatcagg aacatatctt tcgtggctaa ataatgatgt
    19141 tcagacttta aatgatcagg cttttaaaca acttttttta gtaataaaag gaatttctgg
    19201 tactatattt gcagttgtga ctcttaatca ctatcattgg tcattgactg tagccacctt
    19261 gttttcatta atgattatgc tacttgtacc aaaaatcttt gcatcgaaaa tgcgagaagt
    19321 tagtctaaat ttaactaacc aaaatgaagc ttttttaaaa tctagtgaga ctatattgaa
    19381 tggatttgat gtgttagcat ccttgaatct tttatatgta ttgcctaaga aaattaaaga
    19441 agcaggaatt ttattaaaga tggttataca aagaaagaca actgtagaaa cgttagcagg
    19501 cgctattagc ttctttctca atattttttt tcagatatct ctcgtttttt taacaggcta
    19561 tcttgcaata aaaggaatag tgaaaattgg tactattgaa gcaataggag cactaacagg
    19621 tgttattttt acagcgctag gtgaattagg aggtcaatta tcctctatta ttggtacgaa
    19681 gcctattttt ttaaaattgt attcaattaa tccaattgag tcaaataaaa tgaatgatat
    19741 cgaaccaaat gaggtgaata gagattttcc gttatatgaa gcaaaaaata tttgctataa
    19801 gtatggagat aaagaaatat taaaaaactt aaatttttgt tttcaacgta atgaaaagta
    19861 tttaatttta ggtgaaagtg gaagcgggaa atctacatta ttaaaattat tgaatggctt
    19921 tttgagagat tatagtggag aattgcgatt ctgcggggat gatataaaaa aaacctccta
    19981 tttaaatatg gtttcgaatg ttctatatgt agatcaaaaa gcttatttgt ttgaaggtac
    20041 gattagagat aatattttat tggaagaaaa ttatactgat gaagaaatac tacagtcttt
    20101 agagcaagtt ggtttgagtg taaaagattt tcctaataac attttagatt attatgttgg
    20161 tgatgatggg agattactgt caggagggca gaaacaaaaa attactttag ctagagggct
    20221 aattagaaat aagaaaatag tattaattga cgagggaact tctgctatcg ataggagaac
    20281 ttcgttagcg attgaacgta agatattaga tagagaggat ttgactgtca ttattgttac
    20341 ccatgctccg catccggaac ttaaacaata ttttactaag atatatcaat ttccaaagga
    20401 ttttatttaa gaatataggg gagggaaaca tgagattcta ttgtgaagct tatgaggtaa
    20461 ttactgaaga gaaaaaagta tactttaatg atattgagtt agaagttaag tattcctctg
    20521 tcgaagaatt gtttataata tgtgagaaat tattagataa gaaaaaagta tcattttttt
    20581 atgtagatga gaaaccctta aggtatctgt tatttgacta tatatttcta ctagttctag
    20641 ctaaaaaaat atcccaatct tatgaactgc accccaaaag ttagatttat tctgtctaac
    20701 ttttggggtg cagttcattt tgcatagttt tggcattcat cctagatatc catataaaat
    20761 gtctgatatt gttgaaatgt ctaaaaaaat atcagatcta aacgataaaa aagaatttca
    20821 caaaaagaac tgtgagttga ggtttcaaga tagtgttctt gataacataa atagtgtccc
    20881 gagtacaact catttattta gttgtttaaa tattcaaaca ttagtaaaaa ttattttata
    20941 tatttttcga tacaacagtt gtatgaaaat atttaatttt agagataaag agcttatctt
    21001 ttttaataag attgtaaatg ggctgataca aaatattgag gagaatttag aggatgatat
    21061 tgaaaggata ttgaaatatt tatatatatg tttatttaac gaaatattca ttattaagaa
    21121 taaggtgaat ttttttgatg atgtggaatt taatcagaca cttagtgaat ttttagataa
    21181 attgtagagg gaatggttat gagtaacaat actaagtata tatttttatc tccacattta
    21241 gatgacgcaa ttttttcctg tggtgattat atttcaaaat taacttcaga aggagaaatt
    21301 gtacttgtta ttactatatt ttctggttac cctttgagcc aacagctaca gccctctgct
    21361 aagcaatttc ataagttgtg taaccttggg aaatatccga ttgaagaaag gaagaaagaa
    21421 gacaggttag cttgtgaacg tctacagtgt gattttagac acttatcgta ctatgaatgt
    21481 ctctatagga aagatagaaa tggcaatttt ctataccgtc atatctatag tgaattaaaa
    21541 aatgaggaca cattaaagaa tgatatcata aaagagctgt taatgcattt agacgacaaa
    21601 tgtgtcgtat attgtccgct ttcacttggt gaccatgttg atcatgtttt tgtgaatagt
    21661 attggaaggg cgcttgaatt tatgcgttat aaagtaatat attatgagga cttcccatat
    21721 gtaagtgata gtagtatggt tagttatatg ggaaaaacta aagaattaaa aatgtatcaa
    21781 gaggaacttg atgaaaaaca ttatattgat agaatatcat caatattgtg ctataaatct
    21841 cagattttga taatctggaa atcagttgaa aaacttttaa acaatattaa agagttgtat
    21901 ttaaggaatg gggcagctta ttctattaga ttttggatta agaaataagg aagtagtttt
    21961 atgaatatag cagtaattgg tttggggcat gttgggctgg cctacgcgtt actatttgca
    22021 tctaaatata aagttgttgc atatgatata gattctgtaa aaataaataa tttaaaaaag
    22081 ggcattcttc catctaaaaa tgaagagctt atgaagtttt tttgcgagaa taacttaaat
    22141 attacttttt ttgatacatt ttctgaaatt aaaaataata ttgattatta tattattgcg
    22201 cttccgacag attatgatga gaaaattggt agttttaata catatgaaat cgaacaaacg
    22261 gtatcgaaga ttctgagggt aaaacctaat ggaaagatta ttttaaagtc aacagttccg
    22321 atcggctttt caaacaaatt aaaaaggctg tttgatacaa aaaatatcat ttttgtccct
    22381 gaatttttga gagaaggttg ttctatatat gataatttat atccaagtcg catagttgtt
    22441 ggagatgaga cagttgaagg aagaaaaatt gcagagttgt tcctttcgat tagtactcat
    22501 agtactgcca atattaaaaa tgttatgtta gtttctccta ctgaagcaga agcaattaag
    22561 cttttttcta acacattctt agctctccgt gttgcttttt taatgaacta gattcttttg
    22621 ctgagaggag aagcttaaat gctgaagttg taataaaagg tgtttgttta gatccaagaa
    22681 ttggaaattt ttataataat ccttcttttg gatttggagg atattgtctt cccaaagata
    22741 ctaaacaatt aaaaaaagaa tttatagaaa taaatgcccc agtgatagaa gcgattgata
    22801 tttcaaacac aaatagaaaa cagttcatag ttaaacaaat attggaacga aagccaaaga
    22861 tagtaggaat atataaattg gggatgaaat ataattcaga taattacaaa gagtcagcta
    22921 ttttaagtat aattaatgaa ctattgattg tcggtataaa aattttagta tatgaaccaa
    22981 atttaaacgt tagtatagat aacgtaatta ttgaaaagaa ttttgaacta tttacaaaac
    23041 aaagtgatct aattgttgca aatagatggg ataggggcct tgaagcttat aaagataaag
    23101 tttacacaag ggggatctgg ataagagatt aactattgat attaaaaagg caataattta
    23161 taaaatttgt acaaaaaaat gttaaatttt cacattttca tagtatactg tttaatagaa
    23221 agtaggttct ttgtaaccgc tccattataa aatcctttca ctcttccggt atactattag
    23281 gaaaaacata actggaggat attttgagct cacacctcat cgttccagtg gctgttcccc
    23341 aagctcgtgt actgcccaaa aaagttagac attctattta gaacgaggat tgagttctgt
    23401 attgtacaag gctcggtcct tttagagtca gcttaaggct ggctttttta atcaccaaag
    23461 tgtcagaatg ttttgacaaa tgaacacaaa taatgatata atatgcaaaa gctaggaggt
    23521 ggtaggatga ttgaaaaaat ggaactgggg gaattttaca aggaattgcg tttggcgaga
    23581 aagctcaagc agtcagatgt ggcttgtgct ggactaacag cttctcagct atccaagttc
    23641 gaactagggc agtctatgct gtctgcggat aagctcatac tagccatcca agggatcaat
    23701 gtgacctttg atgagtttgg gcacaagctc aacaactatc aagaatctcc acatatgcag
    23761 attggtagaa aggttgtgga tcgctttgct catcaagata tagctggctt agagcaactg
    23821 ttggaggaag tcgagcaagg acagatggcg gagacctatc gtcgtttgaa tgctattgtg
    23881 attaaaaatg cactccattc cttagataaa agctatccgc tagcagagga ggatagcgag
    23941 tttttgacta cctacctcta tgctattgag tcttggacct ggtttgaact ctatcttttt
    24001 tgcaatacca tgcccttctt gagcaatcaa gatctgatct ttttatcaac ctctttgctt
    24061 gaaaaatcca aggaatttaa agagttggta cataatagac tgtatatgaa aagtggcttt
    24121 ctgaatatta tatcagagct catggagcgc aagcttttct cctatatccc aatctttgaa
    24181 gccgagctgg agagtatgct ccgtccatac gatgtttttg agaaagtgtt gtggcagttt
    24241 ttaaagaaga tgagcatttt ccttcaaact aagggaagca atcaaaaaga gattgaacac
    24301 tttatccaat ctctgcaagt attagaaaat ccacaattaa tagccctttt tgaattgcgt
    24361 ttgcagcaat acaaaaagct tatcgattag ttagaaatgg caaaataata atctcagcaa
    24421 cgattttcaa taatgttaaa atttgtttct tcatatttct ccactcctca ttagtagtaa
    24481 ctttattata ccagagaagt aatcaaattc accaaaatcg caaatctgaa atttctataa
    24541 gaaaaaatat caaatatgcg attttctaaa ataagccaat tttcgtgtta tactgtactt
    24601 gtaaagcact tgaagcaaat cctaggtcgc agaagtggtt tacaaatgaa gataattgaa
    24661 ggagtgtaaa agatgttaaa tttacaattt gcagaaacaa tggaattgac agaagctgag
    24721 ttggagatag tttatggagg ggaatttggg aataatgctg ttatcccagc cggtgcttgg
    24781 ggagggttcg ggacaccttg gtcaatcact aatttctgga agaaaaattt taacgataga
    24841 cctgactttg attctgaccg ccgtcgttat taatatccaa agcccttgcc ttttcttggg
    24901 taggggctgt ctttatttca tagtatagga ggaaatagaa tgaaaaagat aatctcacac
    24961 cgctacttta ttatagtttt tctactagtt attgctgacc agaagttcag tgttctagtt
    25021 ttacgcagcg accttgttac tgggctatct gactttgcct attatctgtc ggatatgatg
    25081 ttgaattttc ttgtggtttt atttgctctt attgctatga tttggtcggg gaaatggcag
    25141 aaaatcaata gtagaaagtt taaaggatcc tatcttttct attccttcct agctctgctt
    25201 gcttttgttg tttggaattt cgttaccttt tttcttttcc cacctactcg aaatgaaatt
    25261 tcttatcaac atgctgctcc gacttttaca ggggctacag catttttgat gtattttttc
    25321 tatcctgtga ttgcaggtcc catttttgaa gagataatcc atcggggatt ggtgatgaca
    25381 gctctggaaa aaggaaagaa atgggggcta gatgtacttg gctctgctat tttatttggg
    25441 gtctcgcaca ttagtaatca cggttgggtc ttgacagact ttgtcttcta tatgggtgga
    25501 ggtcttatat ttgcagtctt atttagaatg acaaagtcaa tttattggcc tattggactg
    25561 catatagtct acaatggtat tggtcagctt ttgatgttac tgtaattttg gttgttagta
    25621 gtatcgcggt ctattcttgg ggaaagattc ccatttgaac ttaagaagga gttgtaatga
    25681 aagtatttct tcaaaataga gattttaggc aattaactat caaccagtgg atttcaacgc
    25741 ttggggatac gattttttat ctggccttcc tgaattatgt ggcagatgcg tcttttgccc
    25801 ctttggcgat tttacttatc acgatttcag aaacccttcc ccaagttcta caaatctttc
    25861 tgggagtttt ggcggatttt caacatcatc gtgtcttgaa atacacagtc attagtttta
    25921 caaaattttt gctttactct atagtgtccc tatcgctttc agggcagtct ttttccttgt
    25981 tgctagtaac ctttatttgt atgattaacc tcttgtctga cacattgagt tatttttcag
    26041 gcgccatgct cactccgatt ttcattagaa ttattgggca agatcatctg gcagaagcta
    26101 ttggatttaa acagtcaact gttagtttag tgaaaacaat cagtaatatc ctaggaggag
    26161 tcttactagg tattctatcc atccagttta tttccttact gaacgctctt acctttttaa
    26221 tcgcattttt aggtatcctc ttcataaaaa ctgacctctt gaaagtagaa aaaacgatta
    26281 gctatcaaga aggactctct gtaaaatcct tttgccagca tttgctccaa tcatcgaaat
    26341 tgatatggaa tatgaataag gtgctcttgg ttttgtttat tatctctact agtcaagcag
    26401 tgataaatgt tacagttcct gtctctactc tatttttgag gaatcaaccc tttttgaatt
    26461 tacaaacagg tcaatctctt gccttgctat ccacttttga actgtcagcc ctgattgtcg
    26521 gaagccttgt aagtggctat ctgcaacata ccatttccat aaaaacaact ctctatgcct
    26581 cacttgtcat ccagttgctt cttctagtag gatttgccac agttcgtttt gactggattc
    26641 tcatctttag taccttggat gcctttttcg caggtgttct ctctcctaga ttgcaagaac
    26701 tcgtctttaa acaaatacct gaggagtcaa tgggagcagt tcaatcttct atcagtgcca
    26761 ttacggttgt tttacctagc ttatttacaa tatctttggt aaccattgct actagctttg
    26821 gaactctggc agttagcttt gttttattgc tatttcttct agttgccttt gttatgcttc
    26881 tgaatattcg tgaaagtatt tagtggagaa tttctataat atatgtttga gactggattg
    26941 ccagtctttt tatgatggtc aaaatcaaca gactttttct cttttctgaa tgtgttatag
    27001 tagactgaat ctaaaatagt acgaaacaat tgctaaaaca tttatagaaa ttaattttac
    27061 tttcccaatc gatttgttct catcttattt caatctgcta tacgcgtacg taaataatga
    27121 aaagaattaa ataataggct tgtgcgataa ctatttgaaa caagattagc tggttagaaa
    27181 atccaacaag atagtgaagg aatctaatat aaaatataca taatttagtt tattttatgt
    27241 tataaaagtt gtactaaaag acttacgatt atcttgaatg ccttagggaa acatgctata
    27301 ctacttgtat gattatttta caagctaata aaattgaacg ttcttttgca ggagaggttc
    27361 ttttcgataa tatcaacctg caggttgatg aacgagatcg gattgccctt gttgggaaaa
    27421 atggtgcagg taagtctact cttttgaaga ttttagttgg agaagaggag ccaactagtg
    27481 gagaaatcaa taagaaaaaa gatatttctc tgtcttacct agctcaagat agccgttttg
    27541 agtctgaaaa taccatctat gatgagatgc ttcatgtctt tgatgactta cgtcggacag
    27601 ataaacaact gcgtcagatg gagctggaga tgggtgaaaa gtctggtgag gatttggata
    27661 aactgatgtc agattatgac cgcttatctg aaaattttcg ccaagcaggt ggctttacct
    27721 atgaagctga tattcgagcg attttgaatg gattcaagtt tgacgagtct atgtggcaga
    27781 tgaaaattgc tgagctttct ggtggtcaaa atactcgttt ggctctagct aaaatgctcc
    27841 ttgaaaagcc caatctcttg gtcttggacg agccaactaa ccacttggat attgaaacca
    27901 tctcctggct agagaattac ttggtaaact atagcggtgc cctcattatc gtcagccacg
    27961 accgttattt cttggacaag gttgcgacaa ttacgctaga tttgaccaag tattccttgg
    28021 atcgctatgt ggggaattac tctcgttttg ttgagttgaa ggagcaaaag ctagctactg
    28081 aggcaaaaaa ctatgaaaag caacagaagg aaatcgctgc tctggaagac tttgtcaatc
    28141 gcaatctagt tcgtgcttca acgaccaaac gtgctcaatc tcgccgtaaa caactagaaa
    28201 aaatggagcg tttggacaag cctgaagctg gcaagaaagc agccaacatg accttccagt
    28261 ctgaaaaaac gtcgggcaat gttgttttga ctgttgaaaa tactgctatt ggttatgacg
    28321 gggaagtttt gtcacaacct atcaacctag atcttcgtaa gatgaatgct gtcgctatcg
    28381 ttggtccaaa tggtatcggc aagtcaacct ttatcaagtc tattgtggac cagattcctt
    28441 ttatcaaagg tgaaaagcgc tttggcgcta atgttgaggt tggttactat gaccaaaccc
    28501 aaagcaagct gacaccaagt aatacggtgc tggatgaact ctggaatgat ttcaaactga
    28561 caccagaagt tgaaatccgc aaccgtcttg gggccttcct tttctcagga gatgatgtta
    28621 aaaaatcagt cggcatgcta tctggtggcg aaaaagctcg tttgctttta gctaaattgt
    28681 ctatggaaaa caataacttt ttgattctgg atgagccgac caaccacttg gatattgata
    28741 gtaaggaagt gctagaaaat gccttgattg actttgatgg taccttgctt tttgtcagtc
    28801 atgatcgtta ctttatcaat cgtgtggcaa ctcatgtttt ggaattgtct gagaatggtt
    28861 caactctcta ccttggagat tacgactact atgttgagaa gaaagcaaca gcagaaatga
    28921 gtcagactga ggaagcttca actagcaatc aagcaaagga agcaagtcca gtcaatgact
    28981 atcaggccca gaaagaaagt caaaaagaag ttcgcaaact catgcgacaa atcgaaagtc
    29041 tagaagctga aattgaagag ctagaaagtc aaagccaagc catttctgaa caaatgttgg
    29101 aaacaaacga tgccgacaaa ctcatggaat tacaggctga gctggacaaa atcagccatc
    29161 gtcaggaaga agctatgctt gagtgggaag aattatcaga tcaggtgtaa agatggaaca
    29221 tcttggaaaa gtatttcgtg aatttcgaac aagtggaaat tattctttaa aggaagcagc
    29281 aggcgaatcc tgctctacct ctcagttatc tcgctttgag cttggggagt ctgacctggc
    29341 agtctcccgt ttctttgaga ttttggataa cattcatgta acaatcgaaa atttcatgga
    29401 taaggcaagg aattttcata atcatgaaca tgtgtctatg atggcacaga ttatcccact
    29461 ttactattca aacgatattg caggttttca aaagcttcaa agagaacaac ttgaaaagtc
    29521 taagagttcg acgacttccc tttattttga gctgaactgg attttgctac aaggtctgat
    29581 ttgtcaaaga gatgcgactt atgatatgaa gcaggatgat ttggataagg tagcagatta
    29641 tctcttcaaa acagaagaat ggaccatgta tgagttgatt cttttcggta acctctatag
    29701 tttctacgat gtagactatg tcactcggat tggtagagaa gttatggaga gggaggaatt
    29761 ttaccaagag attagtcgcc ataagagatt agttttgatt ttggccctca attgttacca
    29821 gcattgttta gagcattctt ctttttataa tgccaactat tttgaggctt atacagagaa
    29881 gattattgac aaaggtatta agctttatga gcgtaatgtt ttccattatt taaaaggttt
    29941 tgccttatat caaaaaggac agtgtaaaga aggctgtaag cagatgcaaa aggccatgca
    30001 tatttttgat gtgttaggtc ttccagagca agtagcctat tatcaggaac actacgaaaa
    30061 atttgtcaaa agttaatttt cccaaataag ggaaaaaata aaaagctcct ttcggttttg
    30121 atacaatagt ttcaaaattt gagaggagct ttaatatgaa tcgctatgca gtgcagttga
    30181 ttagccgtgg ggctatcaat aaaatgggaa atatgctcta tgattatgga aatagtgtct
    30241 ggttggcttc tatggggact ataggacaga cagttttagg aatgtatcag atttctgagc
    30301 tcgtcacatc tattctcgtc aatccctttg gcggagttat ttcagaccgt ttttctcgtc
    30361 gtaagatttt aatgacggca gatcttgttt gtgggattct ttgtctggct atttctttca
    30421 taaggaatga tagctggatg attggcgctt tgattgttgc taacattgtg caggctattg
    30481 cttttgcctt ttctcgcaca gccaataaag ctatcataac tgaagtggtg gagaaagatg
    30541 agattgtgat ctataattct cgcttagagc tggttttgca ggttgtaggt gttagctctc
    30601 ctgttctttc cttccttgtt ttacagtttg caagtctcaa tatgacgcta ctgctagact
    30661 cgctgacttt tttcattgct tttgttctag tggctttcct tccaaaagag gaagcaaaag
    30721 ttcaagagaa aaaggctttt actgggagag atatttttgt agatatcaag gatgggttac
    30781 actatatctg gcatcagcaa gaaattttct tccttttgct ggtagcttcc agcgttaatt
    30841 tcttttttgc agcttttgaa tttctacttc ccttttcgaa tcagctttac gggtcagaag
    30901 gagcctatgc aagtatttta actatggggg ctattggttc catcattggg gctcttctag
    30961 ctagtaaaat taaagctaat atttataatc ttttgatttt actggctttg acaggtgtcg
    31021 gagtttttat gatgggatta ccacttccaa cttttctttc cttttctgga aatttagttt
    31081 gtgaattgtt tatgacgatt tttaatattc acttttttac tcaagtacaa accaaggttg
    31141 agagcgaatt tcttggaaga gtactgagta caatttttac cttagctatt ctatttatgc
    31201 ctattgcaaa aggatttatg acagtcttgc caagtgtaca tctctcttct ttcctgataa
    31261 ttggaagtgg tgttatcatc ttgtcttgta tatcgtttat ttatgttcga actcattttg
    31321 aaaaattgat ataaggttgc ttgagtttca aaaataattt caaactaagt gttttttccg
    31381 cccttctcgt ttgtgaggag ggcttgtttt atggtaaaat ggtcttatga ataaaagaat
    31441 gaatgagtta gtcgctttgc tcaatcgcta tgcgactgag tactatacca gcgataatcc
    31501 ctcggttgca gacagtgagt atgaccgcct ttaccgtgag ttggtcgagt tagaaactgc
    31561 ttatccagag caagtgctag cagacagtcc gactcatcgt gttggtggca aggttttaga
    31621 tggttttgaa aaatacagtc atcagtatcc tctttatagt ttgcaggatg ctttttcacg
    31681 tgaggagcta gatgcttttg atgcgcgtgt tcgtaaggaa gtggctcatc cgacctatat
    31741 ttgtgagctg aaaatcgatg gcttatctat ctcgctgact tatgaaaagg ggattttggt
    31801 tgctggggta acacgtggag atggttcaat tggtgaaaat atcacagaaa acctcaagcg
    31861 tgttaaggac atccctttga ctttgccaga agaactagat atcacagttc gtggggaatg
    31921 ttacatgcca cgcgcttcct ttgaccaagt taaccaagtg cgccaagaaa atggagagcc
    31981 tgaatttgct aatcctcgta atgcggcagc aggaactctg cgtcagttgg atacagcagt
    32041 agttgccaag cgtaatcttg caacgtttct ctatcaagaa gccagccctt caactcgtga
    32101 tagccaagaa aagggtttga agtacctaga acaactaggt tttgtggtca atcctaagcg
    32161 aatcttggct gaaaacatag atgaaatctg gaattttatc caagaagtag gacaggaacg
    32221 ggaaaatctg ccttacgata ttgatggagt ggtaatcaag gtcaacgacc tagcaagtca
    32281 agaagaactt ggttttacag ttaaggctcc aaagtgggca gtagcctaca agttccctgc
    32341 cgaagaaaaa gaagctcaac tcttatcagt tgactggaca gttggccgta ccggtgttgt
    32401 aactccaact gctaatctaa caccagtaca acttgccggt acgactgtta gccgtgcgac
    32461 cctgcacaat gtagattata ttgctgaaaa agatatccga aaagacgata cggtcattgt
    32521 atataaggct ggtgacatca tccctgccgt tttacgtgtg gtagagtcca aacgggtttc
    32581 tgaagaaaaa ctagatatcc ctacaaactg tccaagttgt aactctgact tgttgcactt
    32641 tgaagatgaa gtggccctac gttgtatcaa tccgcgttgc cctgctcaaa tcatggaagg
    32701 cttgattcac tttgcttctc gtgatgctat gaatattaca ggccttggtc catctattgt
    32761 tgagaagctt tttgctgcta atttagtcaa ggatgtggcg gatatttatc gtttgcaaga
    32821 agaggatttc ctccttttag agggggttaa ggaaaagtcc gctgctaaac tgtatcaggc
    32881 tatccaagca tcaaaggaaa attctgccga gaagctctta tttggtttgg gaattcgtca
    32941 tgtcggaagc aaggttagtc agcttttact tcaatatttc cattcaattg aaaatctgtc
    33001 tcaggcagat tcagaggaag tggctagtat tgaaagtcta ggtggcgtga ttgccaaaag
    33061 tcttcagact tattttgcga cagaaggctc tgaaattctg ctcagagaat tgaaagaaac
    33121 tggggtcaat ctggactata aaggacagac ggtagtagcg gatgcggcct tgtcaggttt
    33181 gaccgtggta ttgacaggaa aattggaacg actcaagcgc tcagaagcta aaagtaaact
    33241 cgaaagtctg ggtgccaaag tgacaggtag tatttctaaa aagaccgacc tcgtcgtggt
    33301 aggtgcagac gctggaagta aactgcaaaa agcacaagaa cttggtatcc aggtcagaga
    33361 tgaggcatgg ctagaaagtt tgtaatggat cgtttaaaaa cagagtttag agaatatgac
    33421 tatgtctgtt aattgagacg agattgacaa aaatttatta gtgaaataga aacaaagtaa
    33481 aaaggaaaaa taaaaaatgt ataactaccc tatgcgcatt cattaccatc gtaagaatgg
    33541 agaatatgac acttgctcct ttgtaaaaag tcaggatcaa cgaattgatt tgctaaccta
    33601 caaagaagat tattttggag ctttatttag ctttgaacac ccaagttcac atgttataga
    33661 aagcttgaat tttgtggttc atacaggtca aactagtaaa gaatattcta tccgttttaa
    33721 tcactatccc ctattaacag aggtctggat tttggaaggc gatgatagga tttattactc
    33781 tgaaaatcct gctattgcca gtcctttcta taaaaatcaa aatccttttg cctttgataa
    33841 ggccattaac agtgctagtt ttgaccatca ttggggttac caaggagaat tgggttgccg
    33901 tgtagaggac aatcaggctc atttttccct ctggtcacct acagcgacag aagtgcaagt
    33961 tgtcgtttat gaatcagctg ctaatgatgc acccgtttgg aagacttttg agatgaaaag
    34021 aggcaatagc tactcttata atcataagga caatacaatc ggtgtctgga gtttggatgt
    34081 tgaggaagat ttggtaggta aggcttatca gtatcaagtc caattccctc atcaccaaac
    34141 actgacacgt gatccttata caatcgcgac cagccctgat ggcaaacgtt cagctattct
    34201 gagccatgta gaaaagcaag ttgaaaactt cgaggttaag cacggttcgg aggctacttg
    34261 gcgcttggaa aatccatgta aggcagttat ctgtgaaatg catattcgtg atttgactaa
    34321 atcacctaca tcgggtgtag atgaacatct tcgaggaact ttcttgggtg ctgctcaggc
    34381 tggaacagtt aaccaatacg gccagtcaac tgcttttgat tacatcaaga agctgggcta
    34441 caattatgtt caattgcaac caattgcaga ccgtcataaa gaatacgatg aggatggaaa
    34501 tgtaacctac aactggggtt atgatccaca aaactataac gcgccagaaa ctagtttttc
    34561 aactaatcca gatgatccag ctcaggtcat tcgtgatttg aaggtgatgg ttcaagctta
    34621 tcacgatgcg ggtattggag tcattatgga tgtagtctat aaccatacct tctcagttgt
    34681 tgatgcacca ttccaaacaa cagtccctga ttactattat cgtatgaatc cagatggtac
    34741 cttccagaat ggaacgggtg ttggaaatga aacagccagt gaacacgaaa tgtttcgcaa
    34801 gtatatgatt gattctcttc tatactgggt gcaggaatat aatattgacg gcttccgttt
    34861 tgacttgatg gggattcatg atgtcaagac catgcagatg attcgtcaaa gcttggatga
    34921 aatcgactcc aacattatcc tctatggaga aggatgggat atgggaacag gtcttgcccc
    34981 ttatgataag gccaagaagg acaatgccta ccagatgcca aatattggtt tctttaatga
    35041 caatcagcgc gatgctgtca aagggggaga agtttatggt gctatcaagt caggttttgt
    35101 cagtggtgct gcgacagagc caattctagc taaagcaatc ctaggaagtc gtgaattagg
    35161 aagctataca catccaaatc aggtgcttaa ctatgtagaa gcccatgaca attacaatct
    35221 tcacgattta ttggcaaccc ttcatccaga ccaaagttca gagcaaatca tgcgcaaggt
    35281 cgaaactgcc acagccatga atctgctcat gcaggggatg gcctttatgg aaatcggtca
    35341 agaatttggt cgtaccaaac tggttgcgac tggtgaaaat ggtgagttga cccatgatga
    35401 tagagagcgt gcgatgaata gctataatgc tcctgacagt gtgaaccaag tgaactggaa
    35461 cttgattaat gagcgtcaag acagtattga gtttatccgt caagtcatcc gattgaagac
    35521 aaaaactggt gccttttctt actctagcta tgatgaaatt taccatcatg tctttgtgca
    35581 ttctgcgatt gaacatagcg gctaccttat ctatgaagtt cacggcaaag aacacctctt
    35641 ggtggttgtg aatgctaaat cagaacccta tcaatttgaa aatgcaggaa atttagctat
    35701 gttggtaacc aacagtcgct caaaagaaga taatgtttta aatgatatta gtctagctgt
    35761 cttgagtgtt ttataaatac catctatctc gctattttta cacagacaaa ttcccagtta
    35821 tgagtattag taaaaaatcc attcattgaa attgaaagaa tagaaagaac ctggctaaca
    35881 gctcacttgt atagaaaatt tgataaatat tttcacaaaa caagacctcc tatcaaagtt
    35941 tttgaacact tgataggagg tctttttatt atgaagactt ttacctagac tttgtttcag
    36001 caatctatga cagttatagt aggctgaaat tggagtagca cacccttgtt tctgaaacat
    36061 tgtgagaaat tggtttggct gtccccaacc aaattgttca gtttttttat tttactatag
    36121 atgatactca ttcacgctct tcgaaaattt cttcaaacca cattagcctc gccttgacgt
    36181 agtggatttt ttttattttt attgagtata ctttgaaaaa tcaagtttgt gaaaataatc
    36241 tcaaaaattt tgcaaaaagg gttgtgattt tctgaaaatt tggtaaaata tatcttaatc
    36301 attttcagga ggacaagaat ttgacaagat atcagaattt agtaaatgga aaatggaaat
    36361 catctgaaca agaaattacg atttattcac caatcaatca agaagaattg ggtacagttc
    36421 cagccatgac tcagactgaa gctgatgagg ctatgcaagc tgcgcgtgca gccctgccag
    36481 catggcgagc tttatcagca gttgaacgtg cggcttattt acataaaaca gcagctattt
    36541 tagaacgcga taaggaagaa attggtacta tccttgccaa agaagtagca aaagggatta
    36601 aagcagcaat tggagaagta gtgcgtacag cagacttgat tcgttatgct gctgaggaag
    36661 gtctccgtat cactggacaa gcaatggaag gtggtggttt tgaggcagca agtaaaaaca
    36721 aactggctgt tgtccgtcgt gaaccagttg gtatcgtgct agcgattgct ccctttaatt
    36781 atccagttaa tttatctgct tctaaaattg cacctgcctt gattgcaggg aatgtggtca
    36841 tgtttaagcc accaacacaa ggttccattt ctggactctt gttggctaaa gcatttgaag
    36901 aagcagggat tccggcaggt gttttcaaca ccattacagg tcgtggttca gaaattgggg
    36961 attatatcat tgagcacaaa gaagtcaact tcatcaactt tacaggttca actcctattg
    37021 gagaacgtat tggtcgttta gctggtatgc gtcctatcat gttggaactt ggtgggaaag
    37081 atgcagctct tgtactagaa gatgcagatt tggaacatgc tgccaagcaa attgttgcgg
    37141 gagcctttag ctactcagga caacgttgca cggccattaa acgtgtcatt gttctcgaaa
    37201 gtgtagcaga taaattagct actttgcttc aggaagaagt ttctaaatta acagttggtg
    37261 atccatttga caatgctgat attacacctg ttattgacaa tgcttcagcc gacttcattt
    37321 ggggcttgat tgaggatgca caagaaaaag aagctcaggc tcttacacca atcaaacgtg
    37381 agggcaatct tctctggcca gtgctttttg accaagttac aaaagatatg aaagtggcat
    37441 gggaagagcc atttggtcct gttttaccaa tcattcgtgt ggctagtgta gaggaagcta
    37501 ttgcctttgc caacgaatct gaattcggcc ttcaatcatc agtctttaca aatgatttca
    37561 aaaaagcctt tgaaattgct gaaaaacttg aagtaggtac agtccacatt aataataaaa
    37621 cccagcgtgg tccagataat ttcccattcc ttggtgtcaa aggttctgga gctggagtgc
    37681 aaggaattaa atatagcatt gaagcgatga caaatgtcaa atccattgtt tttgatgtga
    37741 aataacgtgt aaaaccagga aattgttttc ctggttttat ttttttgcta taaaataata
    37801 ataattatag aaaaaatacg aactttttgg tattataata gattgaaacc agaatagtac
    37861 agctctactt ctaaaacatt gttagaaatc gatttgactg tcctgatcga tttgtcctgt
    37921 tattatttca ttttgcgata tatagtacat tgaagttaaa atagtacact ttgatttcta
    37981 agacattgtt agaaattaga ttaaattcct taatcgactt gcgcatgttt tatttcattt
    38041 cactatagta gaaaaagaaa ggcgttttcg caattttttg aaaaaatatt gatttacaat
    38101 tgaacgagta agtgaacttg ttgtagattt tcaaaataat taaagaagta tagtaattta
    38161 cttgaatctt ctctaaaaag gtagtataat aaaaacatag aaaacgctta caagagaagg
    38221 ggagtatatg gataatagag aagcattaaa aacctttatg acgggtgaaa atttttatct
    38281 ccaacattat ctaggagcac atagggaaga actaaatgga gagcatggct ataccttccg
    38341 tgtttgggca cctaatgctc aggctgttca cttggttggt gattttacca actggattga
    38401 aaatcagatt ccaatggtaa gaaatgattt tggggtctgg gaagtcttta ccaatatggc
    38461 tcaagaaggg catatttaca aatatcatgt cacacgtcaa aatggtcatc aactgatgaa
    38521 gattgaccct tttgctgtca ggtatgaggc tcgtccagga acaggggcaa tcttaacaga
    38581 gcttcctgag aagaaatgga aggatggact ttggctggca cgaagaaaac gttggggctt
    38641 tgaagagcgt cctgtcaata tttatgaagt tcacgctgga tcatggaaaa gaaattctga
    38701 tggcagtcct tatagttttg cccagctcaa ggatgaactc attccttatc tcgttgaaat
    38761 gaactatact catattgagt ttatgccctt gatgtcccat cctttgggct tgagttgggg
    38821 gtatcagctt atgggttact tcgctttaga gcatgcttat ggcagaccag aggagtttca
    38881 agattttgtc gaggagtgtc atacccataa tattggggtt attgtggact gggtaccagg
    38941 tcactttacc atcaacgatg atgccttagc ctattatgat gggacaccga cttttgaata
    39001 ccaagaccat aataaggctc ataaccatgg ttggggtgcc cttaattttg accttggaaa
    39061 aaatgaagtc cagtccttct taatttcttg cattaagcat tggattgatg tctatcattt
    39121 ggatggtatt cgtgtggatg ctgttagcaa catgctctat ttggactatg ataatgctcc
    39181 atggacacct aataaagatg gcggaaatct caactatgaa ggttattatt ttcttcaacg
    39241 cttgaatgaa gttattaagt tagaatatcc agatgtgatg atgattgcag aagaaagttc
    39301 gtctgcgacc aagattacgg gaatgaaaga gattggtggt ctaggatttg actacaaatg
    39361 gaacatgggc tggatgaatg atatcctccg tttctacgaa gaagatccga tttatcgtaa
    39421 atatgacttt aacctggtga ctttcagctt tatgtatgtt ttcaaggaga attatctctt
    39481 gccattctcg cacgatgaag tggttcatgg caagaagagt atgatgcata agatgtgggg
    39541 agatcgttac aatcaattcg caggcttgcg caatctctat acgtaccaaa tttgtcaccc
    39601 tggtaagaaa ttgctcttca tgggtagcga atacggtcaa ttcctagaat ggaaatctga
    39661 agaacagttg gaatggtcta acctagaaga cccaatgaat gctaagatga agtatttcac
    39721 ttctcagcta aaccagtttt acaaagatca tcgctgtctg tgggaaatcg ataccagcta
    39781 tgatggtatt gaaatcattg atgcggataa tcgagaccag agtgttcttt cctttattcg
    39841 taagggtaaa aagggagaaa tgttagtctg tatctttaac atggtacctg ttgagcggaa
    39901 agattttaca atcggactac ccgttgcagg aatttacgaa gaagtatgga atactgagtt
    39961 ggaagagtgg ggaggcgttt ggaaagaaca taatcaaact gttcaaacgc aagaaggcct
    40021 atggaaagat tatgagcaga ccttaacctt taccctaccg gctatgggag caagtgtatg
    40081 gaaaatcaaa cgtcgcttga aatctactaa aaccgtcaca aataaaaacc aaaaaggagt
    40141 agaaaatgaa aaatgaaatg ttagctttga ttcttgctgg tgggcaagga actcgtctcg
    40201 gtaaactcac tcaaagcatc gcaaaaccag ctgtgcaatt tggtgggcgc taccgtatca
    40261 ttgactttgc cctatcaaac tgtgccaact cagggattca taatgttggg gtggttacac
    40321 agtatcaacc acttgctctc aacaaccata ttgggaatgg ttcaagctgg ggactagacg
    40381 gtattaattc aggtgtctct attcttcaac cttattctgc aagtgaagga aatcgttggt
    40441 ttgagggaac tagtcacgct atttaccaaa atatcgacta tatcgacagt gtcaatcctg
    40501 agtatgtctt gattttgtct ggggaccaca tctacaaaat ggactatgat gatatgctcc
    40561 agtctcataa ggataataat gccagcttga cagtagcagt tttagacgtc cctcttaaag
    40621 aagcgagccg ttttggtatc atgaacacag atgctaacaa tcgtattgtt gaatttgaag
    40681 aaaaaccagc tcaacctaaa tctacaaaag cttctatggg aatctacatt tttgattggc
    40741 aacgccttcg taatatgtta gtcgctgctg aaaagagcaa ggttggcatg tcagactttg
    40801 gtaaaaatgt cattccaaat taccttgagt caggtgaaag tgtttatgct tacgaattta
    40861 gtggttattg gaaagatgtt ggtactattg agtcactttg ggaagcgaac atggagtata
    40921 tttctccaga aaatgccttg gatagtcgta accgtcaatg gaagatttac tcaagaaact
    40981 tgatttcacc accaaacttc ctcggggcaa atgctcatgt ggaagactca ttagttgtag
    41041 acggatgttt cgttgatgga actattaaac attctatcct ttcaacaggc gcgcaagttc
    41101 gcgaaggagc ggaagtcctt gattcagtta tcatgagtgg agctattatt ggtcaaggag
    41161 ctaagattaa acgtgccatt attggtgaag gtgcgattat ttctgacggt gtcgaaattg
    41221 atggaacaga tgaagtacaa gttgtaggat ataatgaagt agtgggggta gcaacagatg
    41281 aagattgata aatattctgc cattttagga aatacagttg gttttcacga tatgtcgaca
    41341 ttgacggacc accgtccagt agcaagtttg ccatttggtg ggaaatatcg tttgattgac
    41401 ttcccacttt caagccttgc taatgcaggt gttcgtagtg tctttggtat tttccagcag
    41461 gataatatca gctcagtctt tgaccatatt cgttcagggc gcgagtgggg cttatcaacc
    41521 cttcttagcc attactatct aggaatttac aatacccgtg tagaaagtag tacagttgga
    41581 aaagaatact accaacagct tcttacttat ttgaaacgtt ctggctcaaa ccaaacggtt
    41641 gccctcaact gcgatgttct tattaacatt gatttgaacc aagttttcca cctacatagt
    41701 acaacaaaag agcctatcac tgtagtttat aaaaaactag ctaagaaaga tatttcagaa
    41761 gtaaatgcaa tcttggatgt agatgaaaca gaccatgttc tttctcataa actctttgat
    41821 agcaagtcaa cagctgaaac gttcaatatg tctacagata tctttgtcgt tgatacacct
    41881 tggttgattg aacacttgga agaagaagct aaaaaagaac atccagagaa attgcgctat
    41941 gttttacggg atttggctgt aaaagaggga gcttttgcct acgagtacac gggctatcta
    42001 gccaatattc actctgttaa atcttattat caagcaaata tcgatatgct tgaatcacaa
    42061 aaattctatt ctcttttctc accaaaccaa aagatttata caaaggtcaa aaacgaagag
    42121 ccaacttatt atgctaatac atctaaggta agcacttctc agtttgcctc tggtagtatt
    42181 attgaaggtc aagtagctaa ttctgttcta tcacgtaata ttcatgtcca taaggatagc
    42241 ttggttaaag atagcctgct cttccctcgt gttgttattg gagaaggggc tcaggtcgaa
    42301 tatgctatct tggacaaagg ggttgaagtt gagcttggtg ttgtgattcg aggaactgca
    42361 gaacatccag ttgtggttaa gaaaggtgct aaagtaacag aggatattca ttcatgaaaa
    42421 ttttatttgt agcagcagag ggtgcaccct tttcaaaaac aggtggtttg ggagacgtca
    42481 ttggcgctct tccaaaatca ctggtaaaag ctgggcacga agttgcagtg attttaccct
    42541 actatgatat ggtagaggct aaatttggaa atcagattga agatgtgctt cattttgagg
    42601 tgagcgttgg ttggcgtaga cagtattgtg gaattaagaa aacagtatta aatggtgtaa
    42661 ccttctactt tattgacaat caatattatt tcttccgtgg tcatgtttac ggtgattttg
    42721 atgacggaga acgctttgcc tttttccaac tggctgccat tgaggctatg gaaaggattg
    42781 actttattcc tgatcttctc catgttcatg actaccatac agctatgatt cctttcttgt
    42841 tgaaggaaaa atactgttgg attcaagcct atgaggacat tgaaacagtt ttaaccattc
    42901 ataatttaga attccaagga caattttcag aaggaatgtt gggtgatttg tttggagttg
    42961 gccttgaacg ttacgctgat ggcacccttc gatggaacaa ctgtctgaac tggatgaagg
    43021 caggtattct ctatgcgaac cgtgtttcaa ccgtttcacc tagctatgct catgaaatta
    43081 tgactagtca gtttggatgt aatttggatc agattcttaa aatggagtct ggtaaagtat
    43141 ctggtatcgt gaatgggatt gatgctgatc tttataatcc tcagacggat gctcttttag
    43201 actatcattt caatcaggaa gatttgtctg ggaaagccaa aaataaggca aaattgcaag
    43261 aaagagttgg cttgcctgtt agagcagacg ttccactggt gggaattgtt tctcgtttga
    43321 cacgtcaaaa aggttttgat gtggtggtcg aaagtcttca ccatatcttg caagaagatg
    43381 ttcagattgt tcttttggga actggcgatc cagcctttga aggagctttc tcatggtttg
    43441 ctcagattta cccagacaag ctatcagcaa atatcacttt tgatgtcaaa cttgctcagg
    43501 aaatctacgc tgcttgtgac ctcttcctca tgccaagtcg ttttgaaccg tgtggcttgt
    43561 ctcaaatgat ggctatgcgt tatggaacct tgccattggt ccatgaagtt ggaggcttgc
    43621 gagatacagt tcgcgctttc aatccaatcg aaggaagcgg tactggcttt agctttgaca
    43681 atctatctcc ttattggtta aattggactt tccaaacagc attggacttg tatagaaacc
    43741 atccagacat ttggagaaac ctacaaaaac aagctatgga gagtgacttc tcatgggata
    43801 cagcctgcaa gtcatacctt gacttgtacc atagtttagt taattaatag ataaaatcgt
    43861 atgatgactt catacgattt ttaggctgtt tagagaggag aactgatgtc tcaagtaaaa
    43921 ggcttgtgtg ttttggatgt agatggaacc ttaatcctag aagaagtgat tgatctttta
    43981 gggagagagg caggtcatga ggcggaaatt tcgcagatta caagtcgagc aatgcgagga
    44041 gagttggtct ttgaaagcag tttaagaaaa agagtgtcct tgttggaagg tcttcctatt
    44101 ttggtctttg ataacgtctt caactcaatt catctatcgc taaatgtccc agagttcatc
    44161 tctattctcc aaaagaatgg catcctagtt ggtctggtgt ctggtggatt tacaccaata
    44221 gttggagaga ttagcaaaat cccttggtat tgcctatttc actgccaacc agcttgaagt
    44281 caaagaaggt cttttaacag gaaaattagt tggacaaatt ataagtcccc aggtcaaaaa
    44341 agaaactctg gaaaaatgga gaaagaaact aaaactttct aaagaaagaa cggtggcaat
    44401 cggtgatggg gttaataatc tattaatgtt gaagtcggcg gagttaggaa tcgccttttg
    44461 ttccaaagaa atgctcaaaa aagaaatacc acatcatgtt gacaagaggg attttttaga
    44521 agttcttcct ttgattgact gtttagaatg agggaaaata tgaagattgt aattgcaccg
    44581 gattcgttta aggaaagctt gacagctcaa caggtagctg aagcaataaa aagaggcttc
    44641 caacaatcga tagcagatgt agaatgtctc ctctgccctg ttggtgatgg gggagaaggt
    44701 actgtagatg ctatccgaca ttctcttgac ctaaaagaaa aatggatcca agtgacagac
    44761 ccttttggac aaaaagaagc catgcgctat tttcaaaaag gggaactggc actatttgaa
    44821 gtagctgact tggttggtct tggaaaaatt ccgctagaga aacgaaatcc acttcaaatc
    44881 caaacttgtg gtattggaga gttgattctc catctcattt ctaaagggat taaagatatt
    44941 tatatcggtg ttggtggcac ggccagtaat gatggaggac tggggattgc tgctggtttg
    45001 tgtgcctttg ctcaggcaag tatcgtgtct ggaattgata cctgcttgga cttaatcaac
    45061 tttgataaga aagtttcaga tgctgacttg gttgttgttg gagaaggaag acttgatagt
    45121 caaagctttg ctgggaaagc gcctataggt gttgcaaaaa gaacccctgt tggagttcct
    45181 gttattgcta tttgcggtag tcttgctgaa gatttacctc ccctaccatt tgaaaatatc
    45241 caagctgtct tttctatttt ggagaaaagt gaacctttag aagatagttt gaaaaatgcc
    45301 agtctctatc tggagcgcac ggctgccaat attgggcact tattaaatat gtgcaagatt
    45361 tagctaaacc atttcttcca taaggatgtt ttggctggtt cttccttttt aacttcccaa
    45421 agttttggaa aagcaagtcg aaggtctttt tcttctactt gaactggtgc attgctatga
    45481 ataaccaggc caaaaggaga agtaatatgc tcttcagata ctatggtggc ttgactatca
    45541 gtttcttttg cttcttttaa gtagaaaact tgcttatcaa attcgatagt tggtgaaatc
    45601 ttcacaaata gtggctttgc tttttcctga aggttttcta aaataaataa aaagcctttt
    45661 tctaactgag ggctatttgc tgtgtcaata tctacatatc caagaactct ttcctcaaaa
    45721 gtaccaagat agcgtctttg ctcatccgga tttattttta acccaccatg agctttttca
    45781 agtaattgtt ttgataaatc tgtcatgaaa acagtatatc ataaaagtta gaataaaaca
    45841 gacaaaagaa agcgattact ttataaagtt aaggaaaagt tgcacaaaga taacgttttt
    45901 tcttgaaaaa ggaggggttt taaggtatta tagaggtgta aaaaatttaa ctcataagga
    45961 gagtaaaaaa tgtcaattat tactgatgtt tacgctcgcg aagtcctaga ctcacgcggt
    46021 aacccaacac ttgaagtaga agtttacact gaatcaggtg ctttcggacg tggtatggtt
    46081 ccatcaggag cttctactgg tgaacacgaa gcagttgaac ttcgcgacgg tgacaaatct
    46141 cgttacggtg gtcttggtac acaaaaagct gttgacaacg taaacaacat cattgctgaa
    46201 gctatcattg gctacgatgt acgtgatcaa caagctattg accgtgctat gattgcactt
    46261 gacggtactc ctaacaaagg taaattgggt gcgaatgcaa tcctcggtgt gtctatcgct
    46321 gtagctcgtg ctgctgctga ctaccttgaa atcccacttt acagctacct tggtggattc
    46381 aacactaaag ttcttccaac tccaatgatg aacatcatca acggtggttc tcactctgac
    46441 gctccaatcg ctttccaaga gttcatgatc ttgccagttg gtgcgccaac atttaaagaa
    46501 gcccttcgtt acggtgctga aatcttccac gctcttaaga aaatccttaa atcacgtggt
    46561 ttggaaactg ccgtaggtga cgaaggtgga ttcgctcctc gtttcgaagg aactgaagat
    46621 ggtgttgaaa ctatccttgc tgcgattgaa gctgctggat atgtaccagg taaagacgta
    46681 tttatcggat ttgactgtgc ttcatcagaa ttctacgata aagaacgtaa agtttacgac
    46741 tacactaaat ttgaaggtga aggtgctgct gttcgtacat ctgcagaaca aatcgactac
    46801 cttgaagaat tggttaacaa atacccaatc atcactattg aagatggtat ggatgaaaac
    46861 gactgggatg gttggaaagc tcttactgaa cgtcttggta agaaagtaca acttgttggt
    46921 gacgacttct tcgtaacaaa cactgactac cttgcacgtg gtatccaaga aggtgctgct
    46981 aactcaatcc ttatcaaagt taaccaaatc ggtactctta ctgaaacttt tgaagctatc
    47041 gaaatggcta aagaagctgg ttacactgct gttgtatcac accgttcagg tgaaactgaa
    47101 gattcaacaa tcgctgatat tgcagttgca actaacgcag gacaaatcaa gactggttca
    47161 ctttcacgta cagaccgcat cgctaaatac aaccaattgc ttcgtatcga agaccaactt
    47221 ggtgaagtag ctgaatatcg tggattgaaa tcattctaca accttaaaaa ataaaatagt
    47281 tcagtgaact attttatccc gaaccatgaa attcaaaagt tcggccgttg atttaacaac
    47341 gtttctagcc cctcggattt tatccgaagg gctatttttg tatttagagg acaaaaaagg
    47401 gacaaaactt tttaaaaaat ctttttcata actttatcca gtacattgat tgcttcatct
    47461 ttcatgttct ttgtgacgtg ggtgtagatg gaagtagtga cttcagagtc ggaatgacca
    47521 accctgtccg tgattgtttt taaaggaatt ttattttctg ataagatgct aatagtggtg
    47581 tgtctgaaga tgtgagggga cagatgtttg ggaattggtt ttttaaggcg ttcgtttgct
    47641 cgctggagag acttgctcaa gatagaacta tgaactggtt ttcctgtatt ggtaacaaaa
    47701 atacggtcgc ttttgtgcca attcttatcg gttgtttcgc ttagacaatt tatatagtca
    47761 attgaaacaa gaacaagaca aaagagcctc ataaaaggta ttgcaacttg gtaataccct
    47821 tttgaggtgc tttttgatat gagcccatgt tttctcaata agattgtact caggcgagta
    47881 gggaggaaga ggtaaaagtt tatgcccaaa ctcttcacac aagagttcta gcttccccat
    47941 tctatggaat cttgcattgt ccattaatat agtagattga aactagaata gtacacctct
    48001 acttctaaaa cattgttaga attagatttt actgtcctga tcgatttgtc ctattcttac
    48061 ttcgttttaa tataataacc aatggtgcgg ttaatgttgg taagagaaat ttctgaaacc
    48121 aagcttcaaa aaagtcgctc gtcatcgtct cttcgtaagt cattgga
//
LOCUS       DBEJHE010000015        46956 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC4 isolate 671759
            SAMN38261586-rid24793303.denovo.15, whole genome shotgun sequence.
ACCESSION   DBEJHE010000015 DBEJHE010000000
VERSION     DBEJHE010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261586
            Sequence Read Archive: SRR26833752
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 46956)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46956)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576136.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576136.1
            Genome Coverage       :: 109x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 19:48:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,067
            CDSs (total)                      :: 2,029
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 131
            CDSs (without protein)            :: 131
            Pseudo Genes (ambiguous residues) :: 0 of 131
            Pseudo Genes (frameshifted)       :: 64 of 131
            Pseudo Genes (incomplete)         :: 59 of 131
            Pseudo Genes (internal stop)      :: 46 of 131
            Pseudo Genes (multiple problems)  :: 32 of 131
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46956
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261586-rid24793303.denovo.15"
                     /strain="GPSC4"
                     /isolate="671759"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            184..546
                     /locus_tag="ACL3EZ_001125"
     CDS             184..546
                     /locus_tag="ACL3EZ_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000842495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0392702.1"
                     /translation="MKSSGIVGLVGGILLLICPFVLLGTAVNTAATTLNGGATAGAFS
                     GVALLLNALKIANLVLGIIAIVYYKGDKHVGAAPSVLMIVSGEVSLIPFLGWVGRILA
                     IIGGSLFLATLKKFKSEE"
     gene            1081..1773
                     /locus_tag="ACL3EZ_001126"
     CDS             1081..1773
                     /locus_tag="ACL3EZ_001126"
                     /EC_number="5.4.2.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006703946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HGR0392703.1"
                     /translation="MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIK
                     EAGIEFDQAYTSVLKRAIKTTNLALEASDQLWVPVEKSWRLNERHYGGLTGKNKAEAA
                     EQFGDEQVHIWRRSYDVLPPNMDRDDEHSAHTDRRYASLDDSVIPDAENLKVTLERAL
                     PFWEDKIAPALKDGKNVFVGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFEFDE
                     KLNVVSEYYLGK"
     gene            1826..4213
                     /locus_tag="ACL3EZ_001127"
     CDS             1826..4213
                     /locus_tag="ACL3EZ_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000620712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HGR0392704.1"
                     /translation="MIRNKKQDYVLAYKQPASTTYMGWEEEALPIGNGSLGAKVFGLI
                     GSERIQFNEKSLWSGGPLPDSSDYQGGNLQDQYVFLAEIRQALEKRDYNLAKELAEQH
                     LIGPKTSQYGTYLSFGDIHIEFSQQGTTLSQVTDYQRQLNISKALATTSYVYKGTRFE
                     REAFASFPDDLLVQCFTKEGLETLDFTIELSLTCDLASDGKYEQEKSDYKECKLDITD
                     SHILMKGRVKDNDLRFASYLAWETDGDIRVWSDRVQISGASYANLFLAAKTDFAQNPA
                     SNYRKKLDLEQQVIDLVDTAKEKGYTQLKSRHIEDYQALFQRVQLDLEADVDASTTDD
                     LLKNYKPQEGQALEELFFQYGRYLLISSSRDCPDALPANLQGVWNSDYHLNVNLQMNY
                     WPAYVTNLLEAVFPVINYVDDLRVYGRLAAVKYAGIVSQKGEENGWLVHTQATPFGWT
                     APGWDYYWGWSPAANAWMMQTVYEAYSFYRDQDYLREKIYPMLRETVRFWNAFLHKDQ
                     QAQRWVSSPSYSPEHGPISIGNTYDQSLIWQLFHDFIQAAQELGLDEDLLTEVKEKSD
                     LLNPLQITQSGRIREWYEEEEQYFQNEKVEAQHRHASHLVGLYPGNLFSYKGQEYIEA
                     ARASLNDRGDGGTGWSEANKINLWARLGDGNRAHKLLAEQLKTSTLQNLWCSHPPFQI
                     DGNFGATSGMAEMLLQSHAAYLVPLAALPDAWSTGSVSGLMARGHFEVSMSWEDKKLL
                     QLTILSRSGGDLRVSYPDIEKSVIKMNQEKIKAKCMGKDCISVATAEGDLVQFYF"
     gene            4463..5164
                     /locus_tag="ACL3EZ_001128"
     CDS             4463..5164
                     /locus_tag="ACL3EZ_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0392705.1"
                     /translation="MAYIEMKHCYKRYQVGDTEIVANRDVNFEIEKGELVIILGASGA
                     GKSTVLNLLGGMDTNDEGEIWIDGVNIADYSSHQRTNYRRNDVGFVFQFYNLVSNLTA
                     KENVELASEIVTDALNSDQVLTDVGLAHRLNNFPAQLSGGEQQRVSIARAVAKNPKIL
                     LCDEPTGALDYQTGKQVLKILQDMSRQKGATVIIVTHNGALAPIADRVIHMHDASVKD
                     VVLNQHPQDIDSLEY"
     gene            5166..7874
                     /locus_tag="ACL3EZ_001129"
     CDS             5166..7874
                     /locus_tag="ACL3EZ_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HGR0392706.1"
                     /translation="MIKRKTYWKDLIQSFTGSKGRFLSILILMMLGSLALVGLKVTSP
                     NMEATANAYLTTAQTLDLAVMSNYGLDQADQEELKQTEGAEVEFGYLTDVTMDNGQDA
                     IRLYSKPERISTFQLRKGRLPQSDKEIALATHLQGQYSVGQEISFKEKEEGHSSLKDH
                     TYTITGFVDSAEILSQRDMGYAGSGSGTLTAYGVILPSQFDQKVYNIARLKYQDLAGL
                     NAFSSAYEEKSKQHQEELEQILSDNGKVRLQLLKKEGQESLDKGQETLDKAQTNLQEG
                     KRRLAAAQARIQAQESQLALFPQVQREQASAQLTQAKQELGKEEAKLKQAEQNLAQEK
                     EKLEKHQQVLDDLAEPRYQVYNRQTMPGGQGYLMYSNASSSIRAVGNIFPVVLYAVAA
                     MVTFTTMIRFVDEERTHAGIFKALGYRSKDIITKFLLYGLVAGTVGTALGSILGHYLL
                     ASVISSVITKGMVVGETQIQFYWTYSLLALVLSLLASVLPAYLVAWRELHAEAAQLLL
                     PKPPVKGAKILLERIGFIWRRLSFTHKVTARNIFRYKQRMLMTIFGVAGSVALLFAGL
                     GIQSSVAGVPSKQFQQIQQYQMLVSENPSATNQDKVELAEVLKGQEILAYQKIYSKTL
                     DKDFKGKAGLQNITLMMIEKEDLTPFIHLQHHQQELTLKDGIVITAKLAQLAGVKVGQ
                     TLEIEGKELKVAAITENYVGHFIYMSQASYEQLYGQLPQANTYLVSLRDTSATSIESQ
                     AGLLMNQSAVSSVVQNASAIRLFDSIASSLNQTMTILVIVSVLLAIVILYNLTNINVA
                     ERIRELSTIKVLGFHNNEVTLYIYRETIVLSLVGIVLGLVAGFYLHQFLIQMISPATI
                     LFYPQVGWEVYVIPVAAVSIILTLLGFFVNYYLRKVDMLEALKSVE"
     gene            complement(7970..8461)
                     /gene="tpx"
                     /locus_tag="ACL3EZ_001130"
     CDS             complement(7970..8461)
                     /gene="tpx"
                     /locus_tag="ACL3EZ_001130"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008379 - thioredoxin peroxidase activity
                     [Evidence IEA];
                     GO_function: GO:0016684 - oxidoreductase activity, acting
                     on peroxide as acceptor [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiol peroxidase"
                     /protein_id="HGR0392707.1"
                     /translation="MVTFLGNPVSFTGKQLQVGDKALDFSLTTTDLSKKSLADFDGKK
                     KVLSVVPSIDTGICSTQTRRFNEELAGLDNTVVLTVSMDLPFAQKRWCGAEGLDNAIM
                     LSDYFDHSFGHDYALLINEWHLLARAVFVLDTDNTIRYVEYVDNINSEPNFEAAIAAA
                     KAL"
     gene            complement(8584..9513)
                     /gene="psaA"
                     /locus_tag="ACL3EZ_001131"
     CDS             complement(8584..9513)
                     /gene="psaA"
                     /locus_tag="ACL3EZ_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000733059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein/adhesin PsaA"
                     /protein_id="HGR0392708.1"
                     /translation="MKKLGTLLVLFLSAIILVACASGKKDTTSGQKLKVVATNSIIAD
                     ITKNIAGDKIDLHSIVPIGQDPHEYEPLPEDVKKTSEADLIFYNGINLETGGNAWFTK
                     LVENAKKTENKDYFAVSDGVDVIYLEGQNEKGKEDPHAWLNLENGIIFAKNIAKQLSA
                     KDPNNKEFYEKNLKEYTDKLDKLDKESKDKFNKIPAEKKLIVTSEGAFKYFSKAYGVP
                     SAYIWEINTEEEGTPEQIKTLVEKLRQTKVPSLFVESSVDDRPMKTVSQDTNIPIYAQ
                     IFTDSIAEQGKEGDSYYSMMKYNLDKIAEGLAK"
     gene            complement(9545..10393)
                     /locus_tag="ACL3EZ_001132"
     CDS             complement(9545..10393)
                     /locus_tag="ACL3EZ_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000559784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease subunit"
                     /protein_id="HGR0392709.1"
                     /translation="MIAEFIDGLQKFHFLQNALITAIVVGIVAGAVGCFIILRGMSLM
                     GDAISHAVLPGVALSFILGLDFFIGAIVFGLLAAIIITYIKGNSIIKSDTAIGITFSS
                     FLALGIILIGVAKSSTDLFHILFGNILAVQDTDMFITMGVGAAILLLIWIFFKQLLIT
                     SFDELLAKAMGMPVNFYHYLLMVLLTLVSVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKSMIFLSSTFGATASVLGLFIGYSFNVAAGSSIVLTAASFFLISFFIAPKQRYLKLK
                     NKHLLK"
     gene            complement(10390..11112)
                     /locus_tag="ACL3EZ_001133"
     CDS             complement(10390..11112)
                     /locus_tag="ACL3EZ_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HGR0392710.1"
                     /translation="MIRIENLSVSYKETLALKDISLVLHGPTITGIIGPNGAGKSTLL
                     KGMLGIIPHQGQAFLDDKEVKKSLHRIAYVEQKINIDYNFPIKVKECVSLGLFPSIPL
                     FRSLKAKHWKKVQEALEIVGLADYAERQISQLSGGQFQRVLIARCLVQEADYILLDEP
                     FAGIDSVSEEIIMNTLRDLKKAGKTVLIVHHDLSKIPHYFDQVLLVNREVIAFGPTKE
                     TFTETNLKEAYGNQLFFNGGDL"
     gene            11403..13295
                     /gene="pepO"
                     /locus_tag="ACL3EZ_001134"
     CDS             11403..13295
                     /gene="pepO"
                     /locus_tag="ACL3EZ_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase PepO"
                     /protein_id="HGR0392711.1"
                     /translation="MTRYQDDFYDAINGEWQQTAEIPADKSQTGGFVDLDQEIEDLML
                     ATTDKWLAGEEVPEDAILENFVKYHRLVRDFDKREADGITPVLPLLKEFQELETFADF
                     TAKLAEFELAGKPNFLPFGVSPDFMDARINVLWASAPSTILPDTTYYAEEHPQREELL
                     TLWKESSANLLKAYDFSDEEIEDLLEKRLELDRRVAAVVLSNEESSEYAKLYHPYSYE
                     DFKKFAPALPLDDFFKAVIGQLPDKVIVDEERFWQAAEQFYSEESWSLLKATLILSVV
                     NLSTSYLTEDIRVLSGAYSRALSGVPEAKDKVKAAYHLAQEPFKQALGLWYAREKFSP
                     EAKADVEKKVATMIDVYKERLLKNDWLTPETCKQAIVKLNVIKPYIGYPEELPARYKD
                     KVVNETASLFENALAFARVEIKHSWSKWNQPVDYKEWGMPAHMVNAYYNPQKNLIVFP
                     AAILQAPFYDLHQSSSANYGGIGAVIAHEISHAFDTNGASFDENGSLKDWWTESDYAA
                     FKEKTQKVIDQFDGQDSYGATINGKLTVSENVADLGGIAAALEAAKREADFSAEEFFY
                     NFGRIWRMKGRPEFMKLLASVDVHAPAKLRVNVQVPNFDDFFTTYDVKEGDGMWRSPE
                     ERVIIW"
     gene            complement(13418..14047)
                     /locus_tag="ACL3EZ_001135"
     CDS             complement(13418..14047)
                     /locus_tag="ACL3EZ_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HGR0392712.1"
                     /translation="MKIHKTVNPVAYENTYYLEGEKHLIVVDPGSHWEAIRQTIEKIN
                     KPICAILLTHAHYDHIMSLDLVRETFGNPPVYIAESEASWLYTPVDNLSGLPRHDDMA
                     DVVTKPAEHTFVFHEEYQLEEFRFKVLPTPGHSIGGVSLVFPDAHLVLTGDALFRETI
                     GRTDLPTGSMEQLLHSIQTQLFTLPNYDVYPGHGPATTIAHEKAFNPFF"
     gene            complement(14387..14629)
                     /locus_tag="ACL3EZ_001136"
     CDS             complement(14387..14629)
                     /locus_tag="ACL3EZ_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0392713.1"
                     /translation="MTRFEEIFEEYKNPQDTFFYPLVYKENTYEKTAISIFALLMLGV
                     CCLFLFSQQSYKKLVQYYANDQNLPSRITYSEYSDK"
     gene            15040..17262
                     /locus_tag="ACL3EZ_001137"
     CDS             15040..17262
                     /locus_tag="ACL3EZ_001137"
                     /EC_number="2.7.6.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019316080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0015970 - guanosine tetraphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HGR0392714.1"
                     /translation="MPKEVNLTGEEVVALTKEYLTEEDVHFVHKALIYAVECHSGQYR
                     KSGEPYIIHPIQVAGILAKLKLDAVTVACGFLHDVVEDTDATLDDLEREFGPDVRVIV
                     DGVTKLGKVEYKSIEEQLAENHRKMLMAMSEDIRVILVKLSDRLHNMRTLKHLRKDKQ
                     ERISKETMEIYAPLAHRLGISSVKWELEDLSFRYLNPTEFYKITHMMKEKRREREALV
                     DEVVTKLEEYTTERHLKGKIYGRPKHIYSIFRKMQDKRKRFEEIYDLIAIRCILDTQS
                     DVYAMLGYVHEFWKPMPGRFKDYIANRKANGYQSIHTTVYGPKGPIEFQIRTKEMHEV
                     AEYGVAAHWAYKKGIKGQVNSKESAIGMNWIKEMMELQDQADDAKEFVDSVKENYLAE
                     EIYVFTPDGAVRSLPKDSGPIDFAYEIHTKVGEKATGAKVNGRMVPLTTKLKTGDQVE
                     IIANPNSFGPSRDWLNMVKTSKARNKIRQFFKNQDKELSVNKGREMLMAQFQENGYVA
                     NKFMDKRHMDQVLQKTSYKTEDSLFAAIGFGEIGAITVFNRLTEKERREEERAKAKAE
                     AEELVKGGEVKVENKETLKVKHEGGVVIEGASGLLVRIAKCCNPVPGDDIVGYITKGR
                     GVAIHRVDCMNLRAQENYEQRLLDVEWEDQYSSSNKEYMAHIDIYGLNRTGLLNDVLQ
                     VLSNTTKNISTVNAQPTKDMKFANIHVSFGIANLSTLTTVVDKIKSVPEVYSVKRTNG
                     "
     gene            17292..17735
                     /gene="dtd"
                     /locus_tag="ACL3EZ_001138"
     CDS             17292..17735
                     /gene="dtd"
                     /locus_tag="ACL3EZ_001138"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004045 - aminoacyl-tRNA hydrolase
                     activity [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-aminoacyl-tRNA deacylase"
                     /protein_id="HGR0392715.1"
                     /translation="MKIIIQRVKKAQVSIEGQIQGKINQGLLLLVGVGPEDQEEDLDY
                     AVRKLVNMRIFSDAEGKMNLSVKDIEGEILSISQFTLFADTKRGNRPAFTGAAKPDMA
                     SDFYDAFNQKLAQEVPVQTDIFGADMQVELVNNGPVTIILDTKKR"
     gene            complement(17774..18189)
                     /locus_tag="ACL3EZ_001139"
                     /pseudo
     CDS             complement(17774..18189)
                     /locus_tag="ACL3EZ_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720030.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            18527..18910
                     /locus_tag="ACL3EZ_001140"
     CDS             18527..18910
                     /locus_tag="ACL3EZ_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000514168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0392716.1"
                     /translation="MQKENVRMRLASESRQILDKLKDDVYNKLGYEVSYSSIVSQAVR
                     EYVPKKERIDWIKLKETAIPFSSLKQSNNWEYQTSLMLEEDVLILLSELQNFFLDVFQ
                     AKRIHRAFCVRLCLKAQFLLSNNDS"
     gene            19091..19390
                     /locus_tag="ACL3EZ_001141"
     CDS             19091..19390
                     /locus_tag="ACL3EZ_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0392717.1"
                     /translation="MNRDVLEFLRTETAEKISLYISEANRLEGDVTLLAPSSQDLEDI
                     KNAMLSNSNLGLKVARLDVMKKIAYASTRNHYLTGATIFGDISKGTYNCDPKSYV"
     gene            complement(19485..19922)
                     /locus_tag="ACL3EZ_001142"
     CDS             complement(19485..19922)
                     /locus_tag="ACL3EZ_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0392718.1"
                     /translation="MKKLYRIHFIAIAVIDLLLFAFFITRLETSFEWLLLSGLIFFLA
                     QGLLLFLLVVRLKHQFAEIYPQINKKIRFYYLGVLTIDFLFFVLLAFISSQRFSSLMP
                     IITACHSTFYYMTADYLGENYPDFYDKHISNTYTILSISSFLV"
     gene            complement(20024..20689)
                     /locus_tag="ACL3EZ_001143"
     CDS             complement(20024..20689)
                     /locus_tag="ACL3EZ_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000260183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0034257 - nicotinamide riboside
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0034258 - nicotinamide riboside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HGR0392719.1"
                     /translation="MAIASGYLNSRLDKFVDWGPWTALVPFGLISVTNVGISMLSTRF
                     TGKLSKWGNYFGIVNTILSGAIDYILGNKAAIITYPVTFLIYTFAIKKWKASQEGRPN
                     QMSQKQVKLAAIIISIIAFLFAFVTNYIGYEGKMNLLAYVTTIAFALSLIANALNALK
                     LTTQWGFWLIYNFVQLTKAGIQGNFANIGKYIFYILNAIGALFVWNDEEVRYIEGNSN
                     KEY"
     gene            complement(20877..21527)
                     /locus_tag="ACL3EZ_001144"
     CDS             complement(20877..21527)
                     /locus_tag="ACL3EZ_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000188500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HGR0392720.1"
                     /translation="MTPNKEDYLKCIYEIGIDLHKITNKEIAARMQVSPPAVTEMIKR
                     MKSENLILKDKECGYLLTDLGLKLVSELYRKHRLIEVFLVHHLDYTSDQIHEEAEVLE
                     HTVSDLFVERLDKLLGFPKTCPHGGTIPAKGELLVEINNLPLADIKEAGAYRLTRVHD
                     NFDILHYLDKHSLHIGDQLQVKQFDGFSNTFTILSNDEDLQVNMDIAKQLYVEKIN"
     gene            21639..22481
                     /locus_tag="ACL3EZ_001145"
     CDS             21639..22481
                     /locus_tag="ACL3EZ_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HGR0392721.1"
                     /translation="MTKIALLSDIHGNTTALEAVLADARQLGVDEYWLLGDILMPGTG
                     RRRILDLLDQLPITARVLGNWEDSLWHGVRKELDSTRPSQRYLLRQCQYVLEEISLEE
                     IEVLHNQPLQIHRQFGDLTVGISHHLPDKNWGRELIHTGKQEDFDRLVTHPPCDIAVY
                     GHIHQQLLRYGTGGQLIVNPGSIGQPFFLDAQLRKDLRAQYMILEFDDKGLVDMDFRR
                     VDYDVAAELQLAKDLRLPYFEVYYESLVNGIHHTHHQEFLRELAQKEGCDRELDDWLK
                     SGND"
     gene            22557..22994
                     /locus_tag="ACL3EZ_001146"
     CDS             22557..22994
                     /locus_tag="ACL3EZ_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HGR0392722.1"
                     /translation="MQIPSRFTIATHMLIIIALEGKESKVTSDFLAASVGVNPVIIRK
                     ILSQLKKAELISVARGTGGTEIVKDLKDISLLDVYQAVECLGKTGQLFSFHDNPNPNC
                     PVGAHIHDVLDQKLERIQLTMEAELGQTSLEKVVADAESQMKD"
     gene            23062..23364
                     /locus_tag="ACL3EZ_001147"
     CDS             23062..23364
                     /locus_tag="ACL3EZ_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000281600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0392723.1"
                     /translation="MYLVIGIVLAFIVSFWKDNRSLWNPVLFLLSLISSYFYLSYLFY
                     KNGYENVQLAFYVFAFVLLPFLLFLSGIFLIYNGVILLKREGRSKPHYLSMLFDFY"
     gene            complement(23455..24528)
                     /locus_tag="ACL3EZ_001148"
     CDS             complement(23455..24528)
                     /locus_tag="ACL3EZ_001148"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2974 domain-containing protein"
                     /protein_id="HGR0392724.1"
                     /translation="MANIFDYLKDVAYDSYYDLPLNELDILTLIEITYLSFDNLVSTL
                     PQRLLDLAPQVPREPTMLTSKNRLQLLDELAQHKRFKNCKLSHFINDIDPELQKQFAA
                     MTYRVSLDTYLIVFRGTDDSIIGWKEDFHLTYMKEIPAQKHALRYLKNFFAHHPKQKV
                     ILAGHSKGGNLAIYAASQIEQSLQNQITAVYTFDAPGLHQELTQTAGYQRIMDRSKIF
                     IPQGSIIGMMLEIPAHQIIVQSTALGGIAQHDTFSWQIEDKHFVQLDKTNSDSRQVDT
                     TFKEWVATVPDEELQLYFDLFFGTILDAGISSINDLASLKALEYIHHLFVQAQSLTPE
                     ERETLGRLTQLLIDTRYQAWKNR"
     gene            24684..25361
                     /locus_tag="ACL3EZ_001149"
     CDS             24684..25361
                     /locus_tag="ACL3EZ_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000548969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGR0392725.1"
                     /translation="MHKILLVEDDQVIRQQVGKMLSEWGFEVVLVEDFMEVLSLFVQS
                     EPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSSRDQAMDIVMAINMGADDFVTKP
                     FDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
                     RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGI
                     GYGLKHA"
     gene            25354..26328
                     /locus_tag="ACL3EZ_001150"
     CDS             25354..26328
                     /locus_tag="ACL3EZ_001150"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HGR0392726.1"
                     /translation="MLDWKQFFLAYLRSRSRLFVYLLSLAFLVLLFQFLFASLGIYFL
                     YFFFLCCFVTILFFTWDILVETQVYRQELLYGEREAKSPLEIALAEKLEAREMELYQQ
                     RSKAERKLTDLLDYYTLWVHQIKTPIAASQLLVAEVVDRQLKQQLEQEIFKIDSYTNL
                     VLQYLRLESFHDDLVLKQVQIEDLVKEIIRKYALFFIQKGLNVNLHDLDKEIVTDKKW
                     LLVVIEQIISNSLKYTKEGGLEIYMDDQELCIKDTGIGIKNSDVLRVFERGFSGYNGR
                     LIQQSSGLGLYLSKKISEELGHQIRIESEVGKGTTVRIQFAQVNLVLE"
     gene            complement(26376..28319)
                     /gene="thrS"
                     /locus_tag="ACL3EZ_001151"
     CDS             complement(26376..28319)
                     /gene="thrS"
                     /locus_tag="ACL3EZ_001151"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004829 - threonine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006435 - threonyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HGR0392727.1"
                     /translation="MINITFPDGAVREFESGVTTFEIAQSISNSLAKKALAGKFNGKL
                     IDTTRAITEDGSIEIVTPDHEDALPILRHSAAHLFAQAARRLFPDIHLGVGPAIEDGF
                     YYDTDNTAGQISNEDLPRIEEEMQKIVKENFPSIREEVTKDEAREIFKNDPYKLELIE
                     EHSEDEGGLTIYRQGEYVDLCRGPHVPSTGRIQIFHLLHVAGAYWRGNSDNAMMQRIY
                     GTAWFDKKDLKNYLQMREEAKERDHRKLGKELDLFMISQEVGQGLPFWLPNGATIRRE
                     LEHYIVNKELASGYQHVYTPPLASVELYKTSGHWDHYQEDMFPTMDMGDGEEFVLRPM
                     NCPHHIQVFKHHVHSYRELPIRIAEIGMMHRYEKSGALTGLQRVREMSLNDGHLFVTP
                     EQIQEEFQRALQLIIDVYEDFNLTDYRFRLSLRDPQDTHKYFDNDEMWENAQTMLRAA
                     LDEMGVDYFESEGEAAFYGPKLDIQIKTALGKEETLSTIQLDFLLPERFDLKYIGADG
                     EDHRPVMIHRGVISTMERFTAILIENYKGAFPTWLAPHQVTLIPVSNEKHVDYAWEVA
                     KKLRDRGVRADVDERNEKMQFKIRASQTSKIPYQLIVGDKEMEDETVNVRRYGQKETQ
                     TVSVDNFVQAILADIANKSRVEK"
     gene            complement(28377..28553)
                     /locus_tag="ACL3EZ_001152"
     CDS             complement(28377..28553)
                     /locus_tag="ACL3EZ_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
                     /protein_id="HGR0392728.1"
                     /translation="MTKQGRYYDETSYTLEQKLSENIWWLLELSQRLDIDILTEMENF
                     LSDKEKQLNVRTRK"
     gene            complement(28560..28700)
                     /locus_tag="ACL3EZ_001153"
     CDS             complement(28560..28700)
                     /locus_tag="ACL3EZ_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000422774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
                     /protein_id="HGR0392729.1"
                     /translation="MELQELVERSWAIRQAYHELEVKHHDFKWTVEEDLLALSNDIGN
                     FQ"
     gene            complement(29131..29331)
                     /locus_tag="ACL3EZ_001154"
     CDS             complement(29131..29331)
                     /locus_tag="ACL3EZ_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001826938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0392730.1"
                     /translation="MRRFYSHLPYYLVILFFYWPLYELFLLVVSDPLTLKGLYINNLL
                     FFTPMVILIVSLLYSYRFRFSL"
     gene            29570..30199
                     /locus_tag="ACL3EZ_001155"
     CDS             29570..30199
                     /locus_tag="ACL3EZ_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HGR0392731.1"
                     /translation="MKLAVIAANGQAGKAIVEEAVKRGHEVTAIVRSENKSQAESIIK
                     KDLFELTKDDLTGFDAVISAFGAYTPDTLPLHSKSIELFNQLLAGTQTRFLVVGGAGS
                     LYIDETKTTRLLDTSDFPEEFKSLAKDQADELDLLRTKNNLNWTFVSPAVDFIPDGEK
                     TGNYILAGEIFTTNEKGISQISYADYAIGLVDELEKGHHIKEHISLLEK"
     gene            30340..30609
                     /gene="rpsO"
                     /locus_tag="ACL3EZ_001156"
     CDS             30340..30609
                     /gene="rpsO"
                     /locus_tag="ACL3EZ_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HGR0392732.1"
                     /translation="MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNEHIK
                     QHKKDHATYRGLMKKIGRRRNLLAYLRKNDVNRYRELINSLGLRR"
     gene            31425..32039
                     /locus_tag="ACL3EZ_001157"
     CDS             31425..32039
                     /locus_tag="ACL3EZ_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000531723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HGR0392733.1"
                     /translation="MGQTIISAIGVYISTSIDYLIILIILFAQLSQNKQKWHIYAGQY
                     LGTGLLVGASLVAAYVVNFVPEEWMVGLLGLIPIYLGIRFAIVGEDAEEEEEEIIERL
                     EQSKANQLFWTVTLLTIASGGDNLGIYIPYFASLDWSQTLVALLVFVIGIIIFCEISR
                     VLSSIPLIFETIEKYERIIVPLVFILLGLYIMYENGTIETFLIV"
     gene            complement(32331..33080)
                     /locus_tag="ACL3EZ_001158"
     CDS             complement(32331..33080)
                     /locus_tag="ACL3EZ_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysophospholipid acyltransferase family protein"
                     /protein_id="HGR0392734.1"
                     /translation="MFYTYLRGLVVLLLWSINGNAHYHNTDKIPNQDENYILVAPHRT
                     WWDPVYMAFATKPKQFIFMAKKELFTNRIFGWWIRMCGAFPIDRENPSASAIKYPINV
                     LKKSDRSLIMFPSGSRHSNDVKGGAALIAKMAKVRIMPVTYTGPMTLKGLISRERVDM
                     NFGNPIDISDIKKMNDEGIETVANRIQTEFQRLDEETKQWHNDKKPNPLWWFIRIPAL
                     ILAIILAILTIIFSFIASFIWNPDKKREELA"
     gene            33213..35549
                     /locus_tag="ACL3EZ_001159"
     CDS             33213..35549
                     /locus_tag="ACL3EZ_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HGR0392735.1"
                     /translation="MDKNKIMGLTQREVKERQAEGLVNDFTASASTSTWQIVKRNVFT
                     LFNALNLAIALALAFVQAWSNLVFFAVICFNAFSGIVTELRAKHMVDKLNLMTKEKVK
                     TIRDGQEVALNPEELVLGDVICLSAGEQIPSDALVLEGFAEVNEAMLTGESDLVQKEV
                     DGLLLSGSFLASGSVLSQVHHVGADNYAAKLMLEAKTVKPINSRIMKSLDKLAGFTGK
                     IIIPFGLALLLEALLLKGLPLKSSVVNSSTALLGMLPKGIALLTITSLLTAVIKLGLK
                     KVLVQEMYSVETLARVDMLCLDKTGTITQGKMQVEAVLPLTETYGEEAIASILTSYMA
                     HSEDKNPTAQAIRQRFVGDVAYPMISNLPFSSDRKWGAMELEGLGTVFLGAPEMLLDS
                     EVPEAREALERGSRVLVLALSQEKLDHHKPQKPSDIQALALLEILDPIREGAAETLDY
                     LRSQEVGLKIISGDNPVTVSSIAQKAGFADYHNYVDCSKITDEELMAMAEETAIFGRV
                     SPHQKKLIIQTLKKAGHTTAMTGDGVNDILALREADCSIVMAEGDPATRQIANLVLLN
                     SDFNDVPEILFEGRRVVNNIAHIAPIFLIKTIYSFLLAVICIASALLGRSEWILIFPF
                     IPIQITMIDQFVEGFPPFVLTFERNIKPVEPNFLRRSMLRALPSALMVVFSVLFVKIF
                     GTSQGWSELEISTLLYYLLGSIGFLSVFRACMPFTLWRVLLIVWSVGGFLATALFPRI
                     QKLLEISTLTEQTLPVYGVMMLVFTVIFILTSRYQARK"
     gene            35650..36327
                     /locus_tag="ACL3EZ_001160"
     CDS             35650..36327
                     /locus_tag="ACL3EZ_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine(22)-N(1))-methyltransferase TrmK"
                     /protein_id="HGR0392736.1"
                     /translation="MISKRLELVASFVSQGAILLDVGSDHAYLPIELVERGQIKSAIA
                     GEVVEGPYQSAVKNVEAHGLKEKIQVRLANGLAAFEETDQVSVITIAGMGGRLIARIL
                     EEGLGKLANVERLILQPNNREDDLRIWLQDHGFQIVAESILEEAGKFYEILVVEAGQM
                     KLSASDVRFGPFLSKEVSPVFVQKWQKEAEKLEFALGQIPEKNLEERQVLVDKIQAIK
                     EVPHVSK"
     gene            36314..37111
                     /locus_tag="ACL3EZ_001161"
     CDS             36314..37111
                     /locus_tag="ACL3EZ_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000881127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0051540 - metal cluster binding [Evidence
                     IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HGR0392737.1"
                     /translation="MLASEVIQAYEAFCPQEFSMEGDSRGLQIGTLDKGIQRVMVALD
                     IREETVAEAIEKGVDLIIVKHAPIFRPIKDLLASRPQNQIYIDLIKHDIAVYVSHTNI
                     DIVENGLNDWFCQMLGIEETTYLQETGPERGIGRIGNIQPQTFWELAQQVKQVFDLDS
                     LRMVHYQENDLQKPISRVAICGGSGQSFYKDALAKGADVYITGDIYYHTAQDMLSDGL
                     LALDPGHYIEVLFVEKIAALLTQWKEKKGWELEILPSQASTNPFRHI"
     gene            37128..38231
                     /locus_tag="ACL3EZ_001162"
     CDS             37128..38231
                     /locus_tag="ACL3EZ_001162"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HGR0392738.1"
                     /translation="MKKVAIIGAGIVGATAAYYLSRESDLEVTVFDHEQGQATKAAAG
                     IISPWFSKRRNKAWYKMARLGADFYVDLLADLEKSGQEIDFYQRSGVFLLKKDESKLE
                     ELYQLALQRREESPLIGQLAILDQAPANELFPGLQGFDNLLYASGGARVDGHLLVTRL
                     LEASQVKLVKEKVTLTLLSSGYQIGEEVFDQVILATGAWLGDMLEPLGYEVDVRPQKG
                     QLRDYQLAQDMEDYPVVMPEGEWDLIPFAGGKLSLGATHENDMGFDLTVDEPLLQQME
                     EAALPHYPVLARVTSRAERVGIRAYTSDFSPFFGQVPELAGVYAASGLGSSGLTTGPI
                     IGYHLAQLIQDKELTLDPLNYPIENYVKRVKSE"
     gene            38238..38429
                     /locus_tag="ACL3EZ_001163"
     CDS             38238..38429
                     /locus_tag="ACL3EZ_001163"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0392739.1"
                     /translation="MKIKEQTRKLAAGYSKHCFEVVDRTDEVSSKHCFEVVDRTDEVS
                     NHTHGKATLTWFELDFRRV"
     gene            38532..39551
                     /gene="galE"
                     /locus_tag="ACL3EZ_001164"
     CDS             38532..39551
                     /gene="galE"
                     /locus_tag="ACL3EZ_001164"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HGR0392740.1"
                     /translation="MQEKILVTGGAGFIGTHTVIELIQAGHQVVVVDNLVNSNRKSLE
                     VVERITGVEIPFYEADIRDTDTLRDIFKQEEPTGVIHFAGLKAVGESTRIPLAYYDNN
                     IAGTVSLLKAMEENNCKNIIFSSSATVYGDPHTVPILEDFPLSVTNPYGRTKLMLEEI
                     LTDIYKADSEWNVVLLRYFNPIGAHESGDLGENPNGIPNNLLPYVTQVAVGKLEQVQV
                     FGDDYDTEDGTGVRDYIHVVDLAKGHVAALKKIQKGSGLNVYNLGTGKGYSVLEIIQN
                     MEKAVGRPIPYRIVERRPGDIAACYSDPAKAKAELGWEAELDITQMCEDAWRWQSKHP
                     NGFED"
     gene            39553..40518
                     /locus_tag="ACL3EZ_001165"
     CDS             39553..40518
                     /locus_tag="ACL3EZ_001165"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HGR0392741.1"
                     /translation="MMISIIVPCLNEEEVLPLFYQALEALLPDLETEIEYVFVDDGSS
                     DGTLELLKAYREQNPAVHYISFSRNFGKEAALYAGLQYATGDLVVVMDADLQDPPSML
                     FEMKNVLDKNVDLDCVGTRRTSREGEPFFRSFSAVLFYRLMQKISPVALPSGVRDFRM
                     MRRSVVDAILSLTESNRFSKGLFAWVGFKTYYLDYPNVERQAGKTSWSFRQLFFYSIE
                     GIINFSDFPLIIAFVAGLLSCFLSLLMTFFVVVRTLILGNPTSGWTSLMAVILFLGGI
                     QLLTIGILGKYISKIYLETKKRPLYLIKEKSDLPDFTEKNKVKRL"
     gene            complement(40569..40775)
                     /locus_tag="ACL3EZ_001166"
     CDS             complement(40569..40775)
                     /locus_tag="ACL3EZ_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HGR0392742.1"
                     /translation="MKITLIPERCIACGLCQTYSDLFDYHDNGIVRFYDDPDQLEKEI
                     SPSQDVLEAVKNCPTRALIGNQEA"
     gene            40827..41303
                     /locus_tag="ACL3EZ_001167"
     CDS             40827..41303
                     /locus_tag="ACL3EZ_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAG1386/EF1546 family surface-associated
                     protein"
                     /protein_id="HGR0392743.1"
                     /translation="MAKEPWQEDIYDQEESRAERRHRNHGGADRMANRILTILASIFF
                     VIVVVMVIVLIYLSSGGSNRTAALKDFHDSDASVVQISSSSSSQPEQSSEPESTSSSS
                     EEAANPEGTIKVLAGEGEAAIAARAGISIAQLEALNPGHMATGSWFANPGDVIKIK"
     gene            41312..41983
                     /gene="cmk"
                     /locus_tag="ACL3EZ_001168"
     CDS             41312..41983
                     /gene="cmk"
                     /locus_tag="ACL3EZ_001168"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004127 - (d)CMP kinase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HGR0392744.1"
                     /translation="MKTIQIAIDGPASSGKSTVAKIIAKDFGFTYLDTGAMYRAATYM
                     ALKNQLGVEEVEALLALLDQHPISFGRSETGDQLVFVGDVDITHPIRENEVTNHVSAI
                     AAIPEVREKLVSLQQEIAQQGGIVMDGRDIGTVVLPQAELKIFLVASVDERAERRYKE
                     NIAKGIETDLETLKKEIAARDYKDSHRETSPLKQAEDAVYLDTTGLNIQEVVEKIKAE
                     AEKRM"
     gene            42113..42451
                     /locus_tag="ACL3EZ_001169"
     CDS             42113..42451
                     /locus_tag="ACL3EZ_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002920966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein YjdM"
                     /protein_id="HGR0392745.1"
                     /translation="MNNLPNCPKCNSEYVYEDGALLVCPECAHEWNPAEVAEVEEGLV
                     AIDANGNKLTDGDTVTLIKDLKVKGAPKDLKQGTRVKNIRIVEGDHNIDCKIDGFGAM
                     KLKSEFVRKI"
     gene            42454..43083
                     /locus_tag="ACL3EZ_001170"
     CDS             42454..43083
                     /locus_tag="ACL3EZ_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Pr6Pr family membrane protein"
                     /protein_id="HGR0392746.1"
                     /translation="MSKHYKLVFYSRIFLFLAAFTGVYLEITRHGGFGMLLYYTVLSN
                     LLVTIFTLYLLKVMSRVGENWQRPSLLRLKGGVTMSIMITCVIYHFLLAPIATNFYTL
                     ENFLCHYIVPIWFLADTLFFDKQGQYKIWDPAVWTILPFLYMMFALFNGLVLKLNIPN
                     AKDNPFPYFFLNVNKGWNVVFKWCLIIFVAYMVAGFIFYFIKQIKRKSS"
     gene            43323..44474
                     /locus_tag="ACL3EZ_001171"
     CDS             43323..44474
                     /locus_tag="ACL3EZ_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HGR0392747.1"
                     /translation="MKQFLERASILALSLVLITSFSISSALPAMFDYYQGYSKEQIEL
                     LVSLPSFGIMMMLLLNGFLEKIFPERLQISLGLLILSLSGTAPFWYQAYPFVFGTRLL
                     FGLGLGMINAKAISIISERYQGKRRIQMLGLRASAEVVGASLITLAVGQLLAFGWTAI
                     FLAYSAGFLVMPLYLLFVPYGKSKKEVKKRAKEASRLTREMKGLIFTLAIEAAVVVCT
                     NTAITIRIPSLMVERGLGDAQLSSFVLSIMQLIGIVAGVSFSFLISIFKEKLLLWSGI
                     TFGLGQIVIALSSSLWVVVAGSVLAGFAYSVVLTTVFQLVSERIPAKLLNQATSFAVL
                     GCSFGAFTTPFVLGAIGLLTHNGMLVFSILGGWLIVISIFVMYLLQKRA"
     gene            44787..45536
                     /gene="truA"
                     /locus_tag="ACL3EZ_001172"
     CDS             44787..45536
                     /gene="truA"
                     /locus_tag="ACL3EZ_001172"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HGR0392748.1"
                     /translation="MTRYKATISYDGYAFAGFQRQSHARSVQEEIEKTLTRLNKGQTI
                     TVHGAGRTDSGVHALGQVIHFDLPYQMDEEKLRFALDTQSPEDIDVISIELVADDFHC
                     RYAKHSKTYEFIVDRGRPKNPMRRHYATHFPYPLDVERMQIAIKKLEGTHDFTGFTAS
                     GTSVEDKVRTITEASLIVDETGQFLTFTFSGNGFLYKQIRNMVGTLLKIGNNRMPVEQ
                     IDLILEKKDRQLAGPTAAPNGLYLKEIRYEE"
     gene            45526..46299
                     /locus_tag="ACL3EZ_001173"
     CDS             45526..46299
                     /locus_tag="ACL3EZ_001173"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008972 - phosphomethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HGR0392749.1"
                     /translation="MKNNRILALSGNDIFSGGGLSADLATYTLNGLHGFVAVTCLTAL
                     TEKGFEVFPTDDTIFQHELDSLRDVEFGGIKIGLLPTVSVAEKALDFIKQRPGVPVVL
                     DPVLVCKETHDVAVSELCQELIRFFPYVSVITPNLPEAELLSGQEIKTLEDMKTAAQK
                     LHDLGAPAVIIKGGNRLSQDKAVDVFYDGQTFTILENPVIQGQNAGAGCTFASSIASH
                     LIKGDKLLPAVESSKAFVYRAIAQADQYGVRQYEANKNN"
     gene            46277..46738
                     /locus_tag="ACL3EZ_001174"
     CDS             46277..46738
                     /locus_tag="ACL3EZ_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HGR0392750.1"
                     /translation="MKQTKTTKIALVSLLTALSVVLGYFLKIPTPTGILTLLDAGVFF
                     AAFYFGSREGAVVGGLASFLIDLLSGYPQWMFFSLVNHGLQGFFAGFKGKSQWLGLIL
                     ATIAMVGGYALGSTLMNGWAAALPEILPNFMQNMVGMIVGFILSQSIKKIK"
BASE COUNT        13711 a         8712 c        10680 g        13853 t
ORIGIN      
        1 taaatagtgt aatattttta caacaataaa tttatatagt tatttctggt ttctgaaaag
       61 tattatatta tattttattt catattatac aaatttttat tttataatat cagaaaatac
      121 tttttttaaa aagcaaatat gatacaattt tatttgaaaa aaaataaaaa aggagatttt
      181 attatgaaat caagtggtat cgtcggtctt gtgggaggaa ttttacttct tatttgtcct
      241 tttgtcttgt tgggaacagc ggtaaataca gctgctacaa ctcttaatgg aggagctact
      301 gcaggggctt tttcaggtgt tgccttactc ttgaatgcct tgaagattgc aaatcttgtt
      361 cttggtatca ttgctattgt ttactataaa ggagataagc atgtaggtgc agctccgtct
      421 gtactaatga ttgtttctgg tgaagttagt ctcattccat tcttaggatg ggttgggagg
      481 attcttgcta ttatcggagg atctctattc cttgcaacat tgaagaaatt caaatcagaa
      541 gaataaaagg tattttagca tgaaaagaac aaaaaagttt atcggtatag gagtagctct
      601 attatctctt tctcttctag ttgcatgtgg aacataaagt tcaaagaata cttcaacaag
      661 taatgatgag aagacagtag caacatccaa tagttcaaaa gaaacaatca ctttcgatac
      721 accggttgta acagacgatg cgattgaatc aatacgcact tatgcagatt atatagatct
      781 ttataaaaat atttttgatg attattttac taaagctgag gaaggtttca aaggcacaac
      841 tatggaaaat aatgactcgt ttactaaact aaaagagtca actcaaaaat tattcgatgc
      901 gcagaaaaaa aggttaaata atgaagatag aatagaaaca accaaaaaca atgtgattgc
      961 caaacattgt caaacagtcc tttccttttt ggttttgact agcttttttg tgaaaaattg
     1021 tgtaaaatag aatagataaa cgaggggaaa cctcggaaaa tttaaaggag aatccatcta
     1081 atggtaaaat tggtttttgc tcgccacggt gagtctgaat ggaacaaagc taaccttttc
     1141 actggttggg ctgatgttga tttgtctgaa aaaggtacac aacaagcgat tgacgctggt
     1201 aaattgatca aagaagctgg tatcgaattt gaccaagctt acacttcagt attgaaacgt
     1261 gctatcaaaa caactaactt ggctcttgaa gcttctgacc aattatgggt tccagttgaa
     1321 aaatcatggc gcttgaacga acgtcactac ggtggtttga ctggtaaaaa caaagctgaa
     1381 gctgctgaac aatttggtga tgagcaagtt cacatctggc gtcgttcata cgatgtattg
     1441 cctccaaata tggaccgtga tgatgagcac tcagctcaca cagaccgtcg ttatgcttca
     1501 cttgacgact cagtaatccc agatgctgaa aacttgaaag tgactttgga acgtgctctt
     1561 ccattctggg aagataaaat cgctccagct cttaaagatg gtaaaaacgt attcgtagga
     1621 gctcacggta actcaatccg tgcccttgta aaacacatca aaggtttgtc agatgatgag
     1681 atcatggacg tggaaatccc taacttccca ccattggtat tcgaattcga tgaaaaattg
     1741 aacgttgttt ctgaatacta ccttggaaaa taaaaaattg taagcctagg attgatttct
     1801 aggcttttta tgttagtatg gaagtatgat aaggaataaa aaacaagatt atgtactggc
     1861 ctacaagcaa ccagcttcaa ccacttacat gggttgggaa gaagaagctt taccgatagg
     1921 taatggttct ttaggagcaa aagtatttgg ccttataggg tctgaacgga ttcaatttaa
     1981 tgaaaaaagt ctctggtctg gaggtccact tcctgatagt tcagattatc agggtggaaa
     2041 tcttcaggat cagtatgttt ttttagctga gattcggcag gctttggaga agagagatta
     2101 caatctggct aaggaactgg ctgagcagca cctaattggg ccaaaaacga gtcaatatgg
     2161 gacctatctg tcttttgggg atattcacat tgagttcagc cagcaaggta cgactttgtc
     2221 tcaggtgacg gactatcaga gacagttgaa tattagtaag gcacttgcga cgacttctta
     2281 tgtctataag ggaacgcgat ttgaacgtga agcttttgcg agttttccag atgatctctt
     2341 ggttcaatgt tttactaagg aagggttgga aactctagat tttactatag aactatcctt
     2401 gacctgtgat ttggcttctg atggaaagta tgagcaggaa aaatctgatt acaaggagtg
     2461 taagttggat attactgatt ctcatatctt gatgaaggga agagttaagg ataatgatct
     2521 gcggtttgct agttatctag cttgggaaac ggatggagat attagagttt ggtcagatag
     2581 ggttcagata tcaggagcca gttatgccaa tctcttcttg gccgctaaga cggattttgc
     2641 ccaaaatcct gctagcaatt atcgcaagaa actagattta gagcaacagg tgatagactt
     2701 ggtggacaca gctaaagaaa agggctatac ccaattgaaa tcaaggcata tcgaggacta
     2761 ccaagcctta ttccagcgtg ttcaattgga tttggaagct gatgttgacg catccactac
     2821 agatgatttg ttaaaaaatt ataagccaca agaagggcag gctttggagg agctgttctt
     2881 ccagtatgga cggtatttat tgattagttc gtccagagac tgcccagatg ctctaccagc
     2941 taacctacag ggagtctgga attcggacta tcacttaaat gtcaatctgc agatgaatta
     3001 ttggccagcc tatgttacca atctcctaga ggcggtcttt ccggtcatca actatgtaga
     3061 tgatttgcgt gtctatggtc gtctagcggc tgtaaagtat gcaggaatcg tctctcaaaa
     3121 aggtgaggaa aatggttggt tggttcatac tcaagcgact ccctttggtt ggacggcacc
     3181 tggttgggat tactattggg gttggtcacc agctgccaat gcgtggatga tgcaaaccgt
     3241 ttatgaagcc tattcatttt atagggacca agactatctc agggagaaaa tttatcccat
     3301 gttgagggaa acggttcgtt tttggaatgc ctttttacat aaggatcagc aggcgcagcg
     3361 ttgggtgtct tctccgtctt attctccaga acatgggccg atttcgattg gcaataccta
     3421 tgaccaatct ctgatttggc agttatttca tgattttatt caggctgctc aggaattggg
     3481 actggatgag gacttgttga ctgaggttaa ggagaagtct gatttactaa atcctttgca
     3541 aatcactcaa tctggtcgaa tcagggagtg gtatgaggag gaagagcagt attttcaaaa
     3601 tgagaaagtg gaggcccagc atcggcacgc ttcccatcta gtgggactct atcctggcaa
     3661 tctctttagc tacaagggac aagagtatat tgaagcggcg cgtgctagcc tcaatgatcg
     3721 tggagatggc ggcacaggct ggtccgaggc taataagatc aatctctggg cgcgtttggg
     3781 agatggcaat cgagcccata aattattggc agagcagtta aagacatcca ccttgcaaaa
     3841 tctttggtgt agccatcctc cttttcagat agatggtaat tttggtgcta ctagtggcat
     3901 ggcagaaatg ttactccagt ctcatgcagc ttatctggta cctctagctg ccctacctga
     3961 tgcttggtca acaggttctg tttcaggctt aatggcacgt ggacattttg aagtgagcat
     4021 gagctgggaa gataaaaaac tcttacagtt gaccatttta tcaaggagtg gaggagattt
     4081 gcgagtttct tatccagata ttgagaagag tgtgattaaa atgaatcaag aaaaaataaa
     4141 agcgaaatgc atggggaaag attgtatttc ggtggcaaca gcagaaggtg atcttgttca
     4201 attttatttt taagaagatg ttataaggca gtaatttgaa actgcctttt aataaggatt
     4261 taagaatata agcagttttc aactagttga aaaaacgtta taatgataat aggaagtaat
     4321 actcaatgaa aatcaaagag cacaaactag gaagctagcc gcaggttgct caaaacagtg
     4381 ttttgaggtt gcagatggaa gctgacgtgg tttgaagaga gattttcgag gagtataatt
     4441 tgtttgatag agggtgggtc tgatggctta tattgagatg aaacactgtt acaagcgtta
     4501 tcaggttggg gacacggaga ttgtggccaa tcgtgatgtg aattttgaga ttgaaaaggg
     4561 ggagctggtt attatccttg gtgcttcagg tgcaggcaag tcaacagttc ttaaccttct
     4621 tgggggaatg gataccaatg atgaagggga aatctggatt gatggtgtta atattgcgga
     4681 ttatagttcc caccagcgca ccaattaccg tagaaatgat gtggggtttg tttttcagtt
     4741 ttataatcta gtttctaatc tgacagctaa ggaaaatgtg gaactggctt ctgaaattgt
     4801 gacagatgcc ttgaattctg atcaggtctt gacagatgta ggtctggctc atcgtctcaa
     4861 taactttcca gcccagcttt ctggagggga gcaacagcga gtctccattg cacgcgcggt
     4921 agccaaaaat cctaaaattc ttctttgtga tgaacctact ggagccttgg attatcagac
     4981 gggcaagcag gttttgaaaa ttctccaaga catgtctcgt caaaagggag cgacggtgat
     5041 catcgtgact cataatggag ctttggcgcc cattgctgat cgcgtgattc atatgcacga
     5101 tgccagtgtc aaggatgtgg tgctcaacca gcatcctcag gatattgaca gtttggagta
     5161 ctagcatgat caagcgaaaa acttattgga aggacttaat tcagtccttc acaggctcca
     5221 aggggcgttt tttatccatc ttgatcctga tgatgttggg atctctagcc ttagtaggcc
     5281 tcaaagtaac cagtcccaac atggaggcga cagctaatgc ttatttaaca actgctcaaa
     5341 ccttggattt ggcagtcatg tctaactatg gcttggatca agcagaccaa gaagaactaa
     5401 aacagacgga gggcgcagag gtcgagtttg gctatttgac agatgtgact atggataatg
     5461 ggcaggatgc cattcgactg tactccaaac cagagcgaat ttcaaccttt cagctaagaa
     5521 agggacgact tcctcagtca gacaaggaaa tcgctttggc cactcatttg caaggccaat
     5581 acagcgtggg acaggagatt agttttaaag aaaaagaaga gggtcattcc tctttaaaag
     5641 accatactta taccattact ggttttgtgg attcggctga aatcctctcc cagcgagata
     5701 tgggctacgc aggaagtgga agtgggactc tgacagccta tggggtgatt ttacctagtc
     5761 agtttgatca gaaagtctac aatatagctc gtttgaaata tcaagattta gcaggtttaa
     5821 atgccttttc atcagcttat gaagaaaaat ccaagcaaca tcaggaagag cttgaacaaa
     5881 ttttatcaga taatggcaag gtacgtctgc aacttttgaa aaaagaagga caagagtctc
     5941 tagacaaggg gcaagagacc cttgacaagg ctcagactaa tttgcaggaa ggcaagcgtc
     6001 gtttagcagc tgctcaagct cgtatacagg ctcaagaaag tcaactagcc ttgtttcctc
     6061 aagttcagag agagcaggct agtgctcaac ttacccaagc caagcaggaa ttgggcaagg
     6121 aagaggccaa actaaagcaa gctgaacaaa atctagccca agaaaaggaa aaattagaaa
     6181 aacatcagca agtcttggac gatttggcgg agccaaggta tcaggtctat aatcgtcaga
     6241 ccatgccagg tggtcagggc tatcttatgt atagcaatgc ttcatccagt attcgagcag
     6301 tgggcaatat ctttcctgtg gtactttatg ccgtagcagc catggtgacc tttacgacca
     6361 tgattcgctt tgtagacgaa gagcgaactc atgcagggat ttttaaggcc ttgggttacc
     6421 gtagtaagga tattatcacc aagtttctcc tttatggact agtagctggg actgtcggaa
     6481 cggctctagg tagtatactt ggtcattatt tgctagccag tgtaatttca agtgtcatta
     6541 caaaaggcat ggtggtggga gaaacccaga ttcagttcta ttggacctat agcttactag
     6601 ctcttgtctt gagcttgttg gcgagtgtgt taccagccta tctggtggct tggagggaac
     6661 ttcatgccga agcagcccag cttctacttc ctaaacctcc tgtcaaagga gctaaaatct
     6721 tattggagcg tatcggtttt atctggcgtc gtctcagttt tactcataag gtaacagccc
     6781 gcaacatctt tcgttataag cagagaatgt tgatgacaat ctttggtgtg gcaggttctg
     6841 tagctctgct ctttgcaggt ttgggaatcc aatcttctgt agcaggagtt ccgtctaaac
     6901 agtttcaaca aatccaacag tatcagatgc ttgtctctga aaatcctagt gcgaccaatc
     6961 aggacaaggt agagctagca gaagtgttga aagggcagga gatactagcc taccagaaaa
     7021 tctattctaa aacgctagac aaggatttca aaggcaaggc tggtcttcaa aacattactc
     7081 ttatgatgat agagaaggaa gatttgactc cctttatcca tcttcaacat catcagcagg
     7141 agctgacatt aaaagatggc atcgttatta cagctaaact cgcccagctg gcaggtgtca
     7201 aggttgggca gactttagaa attgaaggta aggaactaaa ggtcgctgct attactgaga
     7261 actacgttgg tcactttatt tatatgagtc aggctagcta tgagcaactt tacggacagc
     7321 taccccaagc caacacttat ctggtctcat taagggatac cagtgcaact agtatcgaaa
     7381 gtcaggcggg cttgcttatg aatcaatctg cggtgtccag cgttgtccaa aatgcttcag
     7441 ccattcgact cttcgactct atcgctagct cactcaatca gaccatgacc atcttggtca
     7501 tcgtatcggt tctattagct attgtcatcc tttacaatct gaccaatatc aacgtagctg
     7561 agagaatccg tgaactctcc actatcaagg ttctcggttt tcataataat gaagtcaccc
     7621 tctacattta ccgtgagacg attgtgctgt cccttgtggg aatcgtactt ggtctggtag
     7681 ctggtttcta tttacaccaa tttttgattc aaatgatttc gcctgcgact attctctttt
     7741 atccgcaggt aggctgggaa gtctatgtaa tcccagtggc agcagtaagc atcattttga
     7801 ccttgcttgg tttcttcgtc aattattatc tgagaaaggt tgacatgtta gaagccctga
     7861 aatctgtaga gtaaggtagt tatttttagc tgattgaact tctatttact aatattcaaa
     7921 aatcctccgt ttcaaagagc agggaactct ttgtgacaga ggattttttc tatagggctt
     7981 tagcagctgc aattgcggct tcgaagtttg gctcagaatt gatattatcc acgtattcaa
     8041 cgtagcgaat cgtattgtca gtatcgagga caaagactgc gcgtgctaat aggtgccatt
     8101 cgttgatcaa gagggcataa tcgtgcccga aagaatggtc aaagtagtct gaaagcataa
     8161 tggcattgtc aaggccttca gcaccgcacc aacgtttttg agcaaaaggt aggtccattg
     8221 aaacagtcaa tacgaccgtg ttgtccagtc cagccaattc ttcattaaaa cgacgtgttt
     8281 gagttgagca gatgcctgta tcgatagaag gaacgacact caagactttt ttcttgccat
     8341 caaaatcagc cagagatttt ttagaaagat ctgttgtagt aagagaaaaa tcaagcgcct
     8401 tgtcgccgac ttgtagttgt ttacctgtaa agctcacagg atttccgaga aaagttacca
     8461 taggatactc caatcttttt tcttccattg tatctgaaac agtcagaatt ttccaatgat
     8521 ttgaccggaa atgtgggcat agaaaaaacg ccagctcata tgagaatgac gtttttcaga
     8581 ggcttatttt gccaatcctt cagcaatctt gtcaaggttg tatttcatca tgctgtagta
     8641 gctgtcgcct tctttacctt gttctgcgat agagtcagta aagatttgtg cgtagattgg
     8701 gatgtttgtg tcttgagaaa cggttttcat tggacggtca tccacacttg attctacaaa
     8761 gagtgatgga acttttgttt ggcgaagttt ttcaaccaag gtcttgattt gttcaggagt
     8821 tccttcttct tcagtattga tttcccagat gtaggcactt ggaacaccat aggctttaga
     8881 gaagtatttg aatgctcctt cgctggttac aatgagtttc ttttcagcag ggatcttatt
     8941 aaatttatcc ttactttctt tatcaagttt gtctaactta tcagtatatt ctttgagatt
     9001 tttttcatag aattctttat tgttagggtc tttggcgctc aattgtttgg cgatattttt
     9061 agcaaaaata ataccgtttt caaggttaag ccaagcgtgt gggtcttctt ttcctttttc
     9121 attttgacct tcaaggtaga taacatcaac gccgtcgctg actgcgaagt agtctttgtt
     9181 ttcagttttc ttggcatttt ctaccaattt tgtaaaccaa gcattgccac ctgtttcaag
     9241 gttgataccg ttatagaaaa tcaaatcagc ctcagaagtt ttcttaacgt cttcaggaag
     9301 tggttcgtat tcgtgtgggt cttgcccaat cggaacgata ctatgaaggt caattttgtc
     9361 accagcaata tttttagtaa tatcagcgat gattgagttt gtagcaacaa cttttagttt
     9421 ttgaccagaa gttgtatctt tttttccgct agcacatgct acaagaatga ttgcagaaag
     9481 aaagagaacg agtaatgtac ctaatttttt cattagatcc tccaatttat tagggctttg
     9541 ccccttattt taacaaatgt ttatttttca gtttcaaata tcgttgtttg ggagcgataa
     9601 agaagctaat gagaaagaaa ctagcagctg taagcacgat actagaacct gccgcaacat
     9661 taaaactata gccaataaag agtcccaaaa ctgaagcagt agctccgaag gttgaggaaa
     9721 ggaaaatcat gcttttcaga ctattagcat acagataagc agttgcagct ggggtaatca
     9781 gcatggctac aatcaggata gttccgacac tttgcatggc tgtcacagac acgagagtca
     9841 ggagtaccat gagaaggtag tgatagaaat tgacaggcat tcccatggct ttagccaaga
     9901 gttcatcaaa ggaagttatc aagagttgct tgaagaaaat ccagattaac aagaggatgg
     9961 ctgcccccac acccatagta ataaacatat ccgtatcttg gacggccagg atattaccaa
    10021 aaaggatatg gaaaaggtca gttgaacttt tagcgacacc aatcaagatg ataccgaggg
    10081 ctaagaaaga agaaaaggta atgccgatgg cggtatcgct tttgataatc gagtttcctt
    10141 tgatgtaggt aatgatgatg gcagctagca atccaaagac aatggctccg ataaagaagt
    10201 caaggcccaa gatgaaggag agggctacac ctggtaagac agcatgtgaa atggcatctc
    10261 ccatgagtga catcccacgt agaataatga aacatcccac ggctccagct acaatcccga
    10321 cgacaatagc tgttatcaag gcattttgta ggaaatggaa tttttgcaat ccatcgataa
    10381 attctgcaat cataggtcac ctccattgaa aaagagttga ttaccgtaag cttcttttag
    10441 attggtttcg gtaaaagttt cttttgttgg accaaaggca atcacttctc gattgacaag
    10501 taagacttga tcgaagtagt ggggaatctt gctgaggtcg tggtgaacga tgagaaccgt
    10561 cttcccagct tttttcaaat ctctcagcgt attcatgatg atttcctcac tgacagagtc
    10621 aatcccagca aagggttcat ccaagaggat atagtcggct tcctgcacca aacatctggc
    10681 aatcaagacc cgctggaatt gacctccaga cagttgacta atttgacgtt cagcgtagtc
    10741 agctaggccg acgatttcaa gggcctcttg cactttcttc caatgtttag cctttaaact
    10801 tcgaaagaga ggaatagagg gaaatagtcc taacgagacg cattccttga ccttgatggg
    10861 aaagttgtag tcgatattga ttttttgttc gacataggca attcggtgta aggatttttt
    10921 aacttccttg tcatcgagaa atgcctgacc ttgatgtggg ataattccca gcataccttt
    10981 taatagtgtt gatttcccag cgccgtttgg accaatgatg ccggtaattg ttggtccatg
    11041 gagcactagt gaaatatcct taagtgccaa cgtttctttg taggagacac tgaggttttc
    11101 gatacgtatc ataaacttgt attcctcctg tctcttaata tacattaaaa aaaaaattaa
    11161 gtcaagttaa tttttgaaaa aattaaaata ataactgaaa aatagattct aaagataact
    11221 ttcaggataa atttctaaat tataaaacgc atagtatcaa gtgtaaaaaa cttggaatta
    11281 tgcgttttat catggaaaga ttttttataa tagctaaaaa ataatagtta aatggttatt
    11341 aattgcattc cctagtgatt tttgttaaga taaatgcaaa tacaaatgaa agcgagaaca
    11401 agatgacacg ttatcaagat gatttttatg atgctatcaa tggagaatgg caacagacag
    11461 ctgaaatccc agcagataag tctcaaacag gaggttttgt tgatttagac caggaaattg
    11521 aagacctgat gttggcgaca acagacaagt ggttagcagg tgaagaagtg cctgaggatg
    11581 ctatcttgga aaactttgtc aaataccacc gcctagttcg tgattttgac aagagagaag
    11641 ctgacggtat cacacctgtc ttaccactcc ttaaagaatt ccaagaattg gaaacttttg
    11701 cggattttac agctaaacta gcagagtttg agcttgcagg aaaaccaaac ttccttcctt
    11761 ttggtgtatc gccagacttt atggatgcta gaatcaatgt tctatgggct agcgctccaa
    11821 gcacaatctt gccagatacg acctactatg cagaagaaca tcctcagcgc gaagaactct
    11881 tgactctttg gaaagaaagc agcgcaaatc tcctcaaggc ttatgatttc tctgatgaag
    11941 aaattgaaga cttgctagaa aaaagacttg aattggaccg ccgagttgcg gcagtggtgc
    12001 tctctaatga agaaagttca gaatatgcta aactctatca tccatattct tacgaagatt
    12061 tcaagaaatt cgcgcctgcc ctacctttgg atgacttctt caaagcagtt attgggcaat
    12121 taccagacaa ggttattgta gacgaggaac gtttctggca agcagcagag caattctaca
    12181 gtgaggaatc ctggtctctc cttaaagcaa ccttgatttt gagtgttgtc aatctttcaa
    12241 ccagctattt aacagaggat atccgtgttt tgtctggtgc ctacagccgt gccctttctg
    12301 gagttccaga ggcaaaagat aaggtcaaag cagcttatca tctagcacaa gaacctttca
    12361 agcaagccct ggggctttgg tacgcccgtg agaagttctc tccagaagcc aaggcggatg
    12421 tggagaaaaa agtggcaacc atgattgatg tctataagga gcgtctgctt aagaatgact
    12481 ggctcactcc agaaacctgt aaacaggcta tcgtgaagct caatgtgatc aaaccttata
    12541 ttggctatcc agaagaattg cctgcacgtt acaaggataa ggtagtgaat gaaactgcca
    12601 gtctttttga gaatgctcta gcctttgcgc gtgtggaaat caagcacagt tggagtaagt
    12661 ggaaccagcc tgtagactat aaggaatggg gcatgcctgc tcatatggtc aatgcctact
    12721 acaatcctca gaagaacctg attgtctttc cagcggccat tttacaggcg cctttctatg
    12781 acttgcatca gtcatcttct gctaactacg gtggtattgg ggcagtgatt gcccatgaaa
    12841 tttcccacgc ctttgatact aacggggctt cctttgacga aaatggtagc ctcaaggatt
    12901 ggtggacaga gagcgactat gctgccttca aggagaaaac acaaaaagtc attgaccaat
    12961 ttgatggaca ggattcttat ggagcaacca ttaacggtaa attgactgta tcagaaaacg
    13021 tggctgactt gggaggaatc gcagcagcgc ttgaagcagc taagagagaa gcagacttct
    13081 cagcagaaga gttcttctac aacttcggtc gcatctggcg catgaaaggt cgaccagaat
    13141 ttatgaaact tttggctagc gtcgatgtgc acgcaccagc caaactccgt gtcaatgtgc
    13201 aagtaccaaa cttcgacgat ttctttacaa cctatgatgt caaagaagga gacggaatgt
    13261 ggcgttcacc agaggagcgc gtgattattt ggtaatacaa aaaatctagt catcagaaaa
    13321 aaggcatcca atcatgtgtg aaaaccttga taggatgcct tttgtaatag aaagatttgc
    13381 tggatagttt acttaaattt cgattgtcat catcttgcta gaaaaaggga ttgaaggcct
    13441 tttcgtgagc gatagtagta gctggaccat gtcctggata gacatcgtag tttggtaggg
    13501 tgaagagttg ggtctggata ctatgaagga gttgctccat gctaccagtc ggaaggtcgg
    13561 tccgtccgat agtttcgcgg aatagagcat ctcccgtcaa gactaggtga gcatcaggaa
    13621 agactaggga aacaccaccg atagagtgcc ctggggtcgg tagaacctta aaacgaaatt
    13681 cctctagttg gtattcttcg tgaaagacaa aggtgtgttc tgcaggtttt gtgaccacat
    13741 ctgccatatc atcgtggcga gggagaccgg agagattatc gacaggagtg tagagccagc
    13801 tggcttcgct ctctgcgata tagacaggag gattgccaaa cgtctcgcga accaagtcca
    13861 gactcatgat atggtcataa tgggcgtggg tcaagagaat agcacagatc ggtttgttga
    13921 tcttctcgat tgtctgacga atggcttccc aatgactacc aggatcgacg acgatgaggt
    13981 gcttttcgcc ttctagataa taggtatttt cataggcaac aggattcacg gttttatgga
    14041 ttttcatact agctccaatc tcaaagaatg tactaatact cttcgaaaat ctcttcaaac
    14101 cgcgtcaact ttatctgcaa cctcaaagca gtgctttgaa cagcctgcgg ctagctttct
    14161 agtttgctct ttgattttca ttgagtataa attaagtata gcacagttag ggagaatagg
    14221 taaggattta aaatgaactt aaaaaccagc ataactagat gaagacaggt tggttatcaa
    14281 tttatcaata ttggaaaggt gtcaattgcc cttcataggt tgcataaact ccgtcattag
    14341 cttgtttgat agacgtgatg tttagagtgc taccgtagtt ggcttctcat ttgtcgctat
    14401 attcactata agttatccta ctgggcaggt tctggtcgtt agcatagtat tgaacgagtt
    14461 ttttatagct ttgctggctg aataggaaca ggcagcaaac tcctaacatt aggagagcaa
    14521 agatagaaat agcagttttt tcataggtat tctccttata aactaaagga tagaagaaag
    14581 tatcttgagg atttttatac tcttcaaaaa tctcttcaaa ccgcgtcaac gtcgccttgc
    14641 cgtatatatg tgactgactt tgtcagtctt atctacaacc tcaaagcagt gctttgaaca
    14701 gcttgcggct agtttcctag tttgctcttg gattttcatt gagtattaat tccaaaatcc
    14761 agtcaaggta ccagtgtatg tgatacgagt tccaccgttt atctttcgta tcttcaatgg
    14821 aattggggaa gtcagaaagt ctttgggtta caatatggtt tccgttcttc tatctcttct
    14881 tctatcacct aagtttaaaa tctaacttcg tagtatatta tgggccaata attcagaatt
    14941 atcaagcaat tttgaattat ttttttctta ttctgttcca atctagtttt catattctta
    15001 aaaaagtgat aaaatggtag gaagaattgg agagtagaga tgccgaaaga agtgaattta
    15061 acaggcgaag aagttgtcgc tttaaccaaa gaatatttaa cggaagagga tgttcatttt
    15121 gtccataagg ccttgatcta tgctgttgaa tgccacagtg gtcaatatcg caaatcaggc
    15181 gagccttata tcattcaccc tatccaagtg gcaggtattt tagctaagct aaagctggat
    15241 gctgtaacag tagcttgtgg attcttgcat gatgtggtgg aagatacaga tgcgaccttg
    15301 gacgatttgg aaagagagtt tggtcctgat gtgcgggtga ttgttgacgg agttaccaag
    15361 cttggcaagg tcgagtacaa atcgatcgag gagcaattag cggaaaatca tcgcaagatg
    15421 ctcatggcca tgtctgagga catccgcgtt attttggtca aactgtctga ccgcttgcac
    15481 aatatgcgga ccctgaaaca tcttcgaaaa gacaagcagg agcgtatttc caaagaaacc
    15541 atggaaatct atgccccact tgcccatcgt ttggggattt ccagtgtcaa atgggaatta
    15601 gaagacttgt ctttccgtta tctcaatcca acggagtttt acaagattac ccatatgatg
    15661 aaggaaaagc gcagggagcg tgaggccttg gtggatgagg tagtcacaaa attagaggag
    15721 tatacgacag aacgtcactt gaaagggaag atttatggtc gtcccaagca tatttactca
    15781 attttccgca aaatgcagga caagagaaaa cggtttgagg aaatctatga tctgattgct
    15841 attcgttgta ttttagatac ccaaagtgat gtttatgcca tgcttggtta cgtgcatgaa
    15901 ttttggaaac cgatgccagg tcgcttcaaa gactatattg ccaaccgcaa ggccaatggt
    15961 tatcagtcta tccatacgac tgtttatgga ccaaaagggc cgattgaatt ccagattcga
    16021 accaaggaaa tgcacgaggt ggctgagtac ggggttgcgg ctcactgggc ttataagaaa
    16081 ggtataaagg ggcaagttaa cagcaaggaa tcagctattg gaatgaactg gatcaaggag
    16141 atgatggagc tccaagacca ggctgatgat gctaaggaat ttgtggactc tgttaaggaa
    16201 aactatctgg ctgaggagat ttacgttttt accccagatg gagctgtccg ttcccttccc
    16261 aaagattcag gaccgattga ttttgcctac gaaatccata ccaaggtcgg tgaaaaagca
    16321 actggtgcca aggtcaatgg ccgcatggtt ccactgacaa ccaagttaaa gacaggggat
    16381 caggttgaaa ttatcgccaa cccgaactcc tttggaccta gccgtgactg gctcaatatg
    16441 gtcaagacta gcaaggcgcg caataagatt cgccagttct ttaaaaacca agataaggaa
    16501 ttgtctgtca acaagggtcg tgagatgctg atggctcagt tccaagaaaa tggctatgtg
    16561 gcaaataaat ttatggacaa gcgccacatg gatcaagttc tgcaaaagac cagttacaag
    16621 acagaagact ccctctttgc ggccattggt tttggggaaa tcggtgcgat taccgtcttt
    16681 aaccgtctga ctgaaaagga acgccgtgag gaagagcgtg ccaaggccaa ggctgaggca
    16741 gaggagcttg tcaaaggtgg cgaggtcaag gttgaaaata aagaaactct caaggtcaag
    16801 catgaggggg gagtggttat tgaaggtgct tctggtctcc tagtgcggat tgctaagtgt
    16861 tgtaaccccg tgcctggtga cgatattgtt ggctacatta ccaagggtcg tggtgtggct
    16921 attcaccgtg tggactgtat gaacctgcgt gcccaagaaa actacgagca acgtctcctt
    16981 gatgtggaat gggaagacca gtactctagc tcaaataagg agtatatggc ccatatcgat
    17041 atctacggtc tcaaccgtac aggactgttg aacgatgtac tgcaagttct ttcaaataca
    17101 accaagaata tttcaacggt caatgcccaa ccaaccaagg atatgaagtt tgctaatatc
    17161 catgtgtcct tcggtattgc caacctctct acactgacca cggttgtcga taaaattaag
    17221 agtgtgccag aagtttactc tgtcaaacgg accaacggct agttgtccta gctcttacta
    17281 gaaaggctat tatgaaaatc attatccaac gggttaaaaa agcccaagtg agtatagaag
    17341 gccagattca gggaaaaatc aatcagggac ttttattgct agttggtgtt ggaccagagg
    17401 accaagagga agatttggac tatgctgtga gaaaactggt caatatgcgg attttttcag
    17461 acgcagaagg caagatgaac ctgtctgtca aagatattga aggagaaatc ctctctattt
    17521 ctcagtttac cctctttgcg gatactaaga gaggcaatcg tccagccttt acaggggcag
    17581 ctaaacctga tatggcatca gacttctatg atgctttcaa tcaaaaatta gcgcaagaag
    17641 tgcccgttca gacagatatc tttggagcag atatgcaggt tgagctggtt aataacggac
    17701 ccgttaccat tatcctagat actaaaaaga gataaaaaag accaagccca gtcggcttgg
    17761 tctttctcat ctatcataaa atactccaaa aagaaatcgg ttcttgatat gcttggggga
    17821 agtctctttt caggctttgg cagatgcgat aggaagggat gagatgtcct aggatgagga
    17881 gagttccctg aaggaaaagt ggaatatcac ttaaagacac caaggagaga atcatcaggc
    17941 tatcccatag gagaatttgt aaagcaaaac gccagaatct cggtctaatc tgggaataga
    18001 gctgactaaa gtggtcacaa agttggtttg aaagataggt caatagcaca ggatgaaaga
    18061 aaatgagcca accgctataa atcaaaatcc agtcccaagt aagcccccct ttttaaatgt
    18121 caaaaatgcc agcatgattc catcaatgac aaggagttga atggttttga tgaagatgat
    18181 ttttttcatg ctaaaacctc cttttcctta gagacactcc cctacaggta ttttagaatg
    18241 tatattgctt agatattcct tattttatta gctttttaag gtattaaagt agttatataa
    18301 gtttatgaag ggtatcctat cctgcacggc taattttgag ttcgaaactg aggagtttat
    18361 aactcaaaat ttcgattaaa tcagcattta acgatagtat gtttgtcata aaatgataaa
    18421 tttttagatt gtggaaattt tttttaactt aattcttgat tttttttcta aatgtgatat
    18481 acttaattta cgggataaaa aaaccacctt agaaaggtgt gataatgtgc aaaaagagaa
    18541 tgttagaatg cgtttagcgt ctgaatccag acagatatta gataagctta aagatgatgt
    18601 ttacaataaa ttaggctatg aagtaagcta ttccagtatt gttagtcaag ctgttagaga
    18661 atacgttcct aaaaaagaac gtatagattg gataaaatta aaagagacag ctataccctt
    18721 ttcatcgtta aaacagagca ataattggga gtaccagaca tcacttatgt tagaggaaga
    18781 tgtattaatc ttactgtctg aactacaaaa ttttttctta gatgtcttcc aagcgaaacg
    18841 tatacatagg gcattttgtg tacgcctatg cttgaaagca caatttttat taagtaataa
    18901 tgattcttaa tactatcaat attaatgcgg agtgtaatgc tccgctaaaa taaaacctat
    18961 tacgggataa aaacactact ttatttagga tggaaagagg aacgaatgaa gatgaaagct
    19021 agagattcac cattgaattg attttgtttt tagaaaaaat caataattag aaaaaatacg
    19081 aggtaaaaaa atgaatagag atgtattaga gtttctgaga acagagaccg ctgaaaaaat
    19141 tagtctttat ataagcgagg ctaatagatt ggagggcgat gtaactctac tcgcacctag
    19201 ttctcaagat ttggaagata ttaaaaatgc tatgctttcc aattctaatc tcggattaaa
    19261 agttgcgaga ctggatgtga tgaagaaaat agcatatgct tctacaagaa atcattattt
    19321 aacaggggct acgatttttg gggatatttc gaaaggaaca tacaattgtg atcctaaaag
    19381 ttatgtctaa tataagggag gttaatccct ccccttgttt ttgaaaatcg aaaggaaaag
    19441 tataaaaatg aaagttaatg aatatttctg gagaacgagc tgtcttatac taaaaaagaa
    19501 gaaatcgata aaatagtata cgtgttagag atgtgtttgt cgtaaaagtc tggatagttt
    19561 tctcctaggt agtcagctgt catataataa aaagtagaat ggcaagcagt gataattggc
    19621 ataagagatg aaaaacgctg agaactaatg aaggctaaga gaacaaaaaa tagaaaatca
    19681 atggtgagaa cccctaaata gtagaagcga atctttttat tgatttgagg ataaatctca
    19741 gcgaattgat gtttgagtcg gacgaccaag agaaatagca ggagtccttg agcaaggaag
    19801 aaaattaaac cagagagcaa gagccactca aaagatgtct cgagtctagt gataaaaaat
    19861 gcaaatagta gcaaatcaat aactgcaatt gctataaaat ggattctata gagttttttc
    19921 atgacaagac cttcctcttt tatctaactt cattctactc caaaagaatg ggagttacaa
    19981 ctaaaatgat aaaaatagca gaagggagat tctcttaagt tggctagtat tctttatttg
    20041 agtttccttc tatgtatcta acttcttcat cattccagac aaataaagct ccgattgcat
    20101 tgaggatata aaagatgtat ttaccgatat tggcgaagtt tccttgaata ccagcttttg
    20161 tcagctgaac gaaattgtaa atcaaccaaa agccccactg agttgttagt ttcaatgcat
    20221 tcaaagcatt ggcaatgagg gacagtgcaa aggcaatagt tgttacgtag gcaaggagat
    20281 tcatcttgcc ctcatatccg atatagttgg tcacaaaggc aaagaggaag gcgatgatgg
    20341 aaatgatgat ggccgccaat tttacctgtt tttggctcat ttggttgggt ctgccttctt
    20401 gcgaagcttt ccatttcttt atagcaaagg tataaatgag gaaggtgacg ggataggtaa
    20461 tgatggccgc cttatttcca aggatataat caatagcacc ggacaaaatg gtattaacaa
    20521 taccaaagta atttccccat ttgcttaatt tccccgtgaa acgagtggac aacatggaaa
    20581 tcccaacgtt ggttacggaa atcaatccaa agggtacaag agctgtccat ggtccccagt
    20641 ctacaaattt atcgaggcgt gagttgaggt aaccagatgc aatcgcaatc caacgaccaa
    20701 agcaaccccg aagaggtcaa actatttaga tgtagcaaaa atttttagtg attttttcat
    20761 aggttaaact acctttcttt ttttcaaata ttctcccacc aaatgaaagt aaaataaaat
    20821 gatagaaata aaaccctgaa aataaaactt tcagggttgg taggggactt gagaaattag
    20881 ttgattttct cgacatagag ttgttttgca atgtccatat tcacttgtaa atcctcgtcg
    20941 ttactgagga tagtgaaggt attgctgaag ccatcaaact gcttgacttg gagctggtca
    21001 ccgatgtgaa gtgagtgctt gtccagataa tggagaatgt caaaattatc gtgcacccga
    21061 gtcaggcggt aggcgccagc ttccttgata tcagctagtg ggaggttatt gatttcaacg
    21121 aggagttctc ccttggcagg aatagttcct ccgtgggggc aggttttagg gaaacctagc
    21181 agtttatcta gtctttccac gaacaggtca gagacagtgt gttccaagac ctcagcttcc
    21241 tcgtgaatct ggtcacttgt atagtctaaa tgatgaacta gaaaaacttc aatcaagcgg
    21301 tgcttacgat agagctcaga gactagtttg agaccgaggt cagtcagtag atagccacat
    21361 tccttgtcct ttaggatgag gttttcactt ttcattcgtt tgatcatttc agttacggca
    21421 gggggagaga cttgcatgcg agccgcaatt tccttgttgg taatcttatg caggtctatg
    21481 ccaatttcat aaatacattt tagatagtct tctttgtttg gggtcattcg tttcctcttg
    21541 tctaatatct ttatctagta tatcaaaaaa agctagattt ctctagctgt gactttttat
    21601 gttatactta ttgcaagaga aaaaacgagg agatggatat gacgaaaata gctcttcttt
    21661 cagatattca tggaaatacc accgccttgg aggctgtttt ggcagatgct cggcagctag
    21721 gagtggatga atactggctt ttgggagata ttctcatgcc agggacagga cgtagaagga
    21781 ttttggactt gttggatcaa ctaccgatta cggctagagt tttgggaaac tgggaagaca
    21841 gtctttggca tggtgtccgt aaggaattgg atagtactcg ccccagtcaa cgctatctct
    21901 tgcgccagtg ccagtatgtt ttagaggaaa tttccctaga agaaattgaa gtgctccaca
    21961 atcaacctct tcaaattcat cgtcagtttg gggatttgac ggtgggaatt agtcatcatc
    22021 tgcctgataa gaactggggg cgagagttga ttcatactgg caaacaagag gattttgacc
    22081 gcttggtgac tcatcctccc tgtgatattg ctgtttatgg acatattcac cagcagttgc
    22141 ttcgttacgg gactggtggg caattgattg tcaatccggg ttcgattggc caacctttct
    22201 ttttggacgc tcagctacgg aaggacttgc gggcccagta tatgattttg gagtttgatg
    22261 acaaaggcct ggtagatatg gacttccgac gggtagacta cgatgtggca gcggaattgc
    22321 agctggctaa agacctgaga cttccctatt ttgaggttta ctatgaaagt ctggtcaatg
    22381 ggatccacca tactcatcat caggaatttt tgagagaatt ggctcagaaa gagggctgcg
    22441 accgggagtt agacgactgg ttgaaaagtg gtaacgattg acattacaac taaaaagggt
    22501 ataataatag aaaaagaaga gtagaggcag ggtagcctcg taaaaaggag aagaggatgc
    22561 aaattccaag tagatttacc attgcgactc atatgctgat aatcattgcc ctcgagggga
    22621 aggaaagcaa ggtgaccagt gattttctgg ctgctagtgt cggggtcaat cctgtcatta
    22681 tcagaaagat cttgtcccag ttgaagaagg cagagctgat ttcagtagcg cgtggaacgg
    22741 gcggaacaga gattgtcaag gaccttaagg atattagtct tttagatgtt tatcaggcgg
    22801 tcgaatgtct tggtaagaca ggtcaactct tcagtttcca tgacaatccg aatccaaatt
    22861 gccctgtagg agctcatatt catgatgttt tggatcaaaa attggagaga attcagttga
    22921 ctatggaggc agaacttggt caaaccagtc tagaaaaagt cgtggccgat gcagagagtc
    22981 agatgaagga ttaagaggga taaatgccct cttttttctt tggataatta tgataaaatg
    23041 tagctattaa aggagtaaga aatgtatctc gttataggaa ttgtattagc ctttatagtg
    23101 tcattttgga aggataatag aagtttgtgg aatccagtat tatttttatt atccctcatt
    23161 tcaagttatt tttatctatc ctaccttttt tataaaaatg gatacgagaa tgttcagtta
    23221 gctttttatg tatttgcctt tgtcttactt ccttttttgc tttttctaag tggcatcttt
    23281 ttaatctata atggggtcat tttgttgaag cgagagggac gttccaagcc ccattatctc
    23341 tcaatgctct ttgattttta ttgactatta gattctattt aaaaagactt agaatgcaca
    23401 tgaaagtatg tattctaggt cttttgtttt gtatacattt aattttcaag agtattatct
    23461 atttttccat gcctggtaac gagtatcaat caataactgg gtaaggcgac ccaaggtttc
    23521 tctttcttct ggagtgaggg attgagcttg gacaaagaga tgatgaatgt attcaagcgc
    23581 ctttaaggaa gccaagtcat tgatagagct aataccagca tcaagaatag tgccaaagaa
    23641 gaggtcgaag tagagctgaa gttcttcgtc agggactgtg gccacccatt ctttaaaggt
    23701 tgtgtctact tgccggctat cactgttggt cttatccagt tgaacgaagt gcttgtcctc
    23761 aatctgccaa ctaaaggtat cgtgctgggc gatgccaccc agggcagtac tctgaacgat
    23821 gatttggtga gcaggaattt ccagcatcat accgataatg gaaccttgtg gaatgaatat
    23881 cttgcttcta tccattatcc tttgataacc cgcagtctgt gtcaattctt gatggagacc
    23941 aggtgcatca aatgtataaa ctgctgtgat ctgattttgc aaactttgct caatttggct
    24001 agcagcatag atagcgagat ttcctccctt ggaatgccca gccagaataa ccttttgctt
    24061 aggatgatgg gcaaaaaagt tctttaaata gcgaagggcg tgcttttgag caggaatttc
    24121 cttcatatag gtcaggtgga aatcttcctt ccagccaatg atactgtcat ctgtcccacg
    24181 aaagacaatc agataggtat cgaggctgac acgataagtc atagccgcaa attgcttttg
    24241 cagttcaggg tcgatgtcgt tgataaaatg ggagagtttg caatttttga agcgcttgtg
    24301 ttgagccaat tcatctaata attgaaggcg atttttgcta gtaagcatgg tgggctctct
    24361 tggaacctga ggtgctagat ctaaaagacg ttgaggaagt gtggagacca gattatcaaa
    24421 ggagaggtag gtgatttcta ttaaggttag aatgtctaac tcattcaagg gaaggtcgta
    24481 ataagaatca tatgcgacat ctttcagata gtcaaaaata ttggccataa gagctccttt
    24541 ctttttattt atcttagcaa atttccctca aattagctag tagcatagcc tgtttgtact
    24601 ggctaaaaac aggctatttc aaattcagtt tcagaccatc tagcatggaa aaatctgtta
    24661 taataatgga aaaggagaag cgcatgcaca agattttatt agtggaagat gatcaggtca
    24721 ttcgtcaaca ggtcgggaaa atgctctctg aatggggatt tgaagtggtc ctggtagaag
    24781 actttatgga agttttgagt ctatttgttc agtcggaacc tcatctggtc ctcatggata
    24841 ttggtttgcc cttgtttaat ggttatcact ggtgtcagga aatccgcaag atttccaagg
    24901 tacctatcat gtttctttct tcgagagacc aggctatgga tattgtcatg gcaatcaata
    24961 tgggggcaga tgactttgtg accaagcctt ttgaccagca ggttctttta gccaaggttc
    25021 agggcttgtt gcgtcgttcc tatgagtttg ggcgtgatga gagtttgctg gaatatgctg
    25081 gtgttatcct caataccaaa tccatggatt tacattatca agggcaagtc ttgaatttga
    25141 ccaagaatga attccagatt ttacgcgtgt tatttgagca tgcaggcaac atcgtagcac
    25201 gtgacgacct gatgcgggaa ctttggaaca gtgacttttt cattgatgat aataccctct
    25261 ctgtcaatgt ggctcgtttg cgtaaaaagt tggaggagca gggattggta ggatttatcg
    25321 agaccaagaa aggaataggg tacggattga agcatgcttg attggaaaca attttttcta
    25381 gcctatctgc gctcccgtag tcgtcttttt gtctatctgc tttctttggc atttcttgtc
    25441 ttactctttc agtttttatt tgccagtcta ggaatttact tcctctactt tttcttcttg
    25501 tgttgctttg taaccatctt atttttcact tgggacatat tggtggaaac gcaggtctat
    25561 cgccaggaac ttctctatgg agagagggaa gccaagtctc ctttggaaat agctttagca
    25621 gaaaaattag aagcgcgtga gatggaactc tatcagcaga ggtcaaaagc agaaagaaaa
    25681 ctgacggatt tgctggatta ctataccttg tgggtccatc agataaagac ccccattgca
    25741 gccagtcaac tcttagttgc agaagtggtc gaccgccaac tgaagcagca gctagaacag
    25801 gaaattttca aaatcgactc ctataccaac ctagttttac agtacctgcg tttagaaagt
    25861 ttccatgatg atttggtctt aaagcaggtt caaattgagg acttggtcaa ggaaataatt
    25921 cgtaaatatg ctcttttctt tattcaaaaa ggcttaaatg tcaatctaca tgaccttgat
    25981 aaagaaatcg tgacggataa aaagtggctg ctagtggtta ttgagcaaat catctcaaac
    26041 agtctcaagt acaccaagga aggtggtctg gagatttata tggatgacca agagctttgt
    26101 atcaaagata cgggaatcgg gataaaaaac agtgatgtcc tccgagtatt tgaacgtggc
    26161 ttttcaggat acaatggccg tttgatccag cagtcctctg gacttggcct ttatctatct
    26221 aagaaaattt ctgaagaact ggggcatcag attcgtatcg agtctgaggt cggaaaagga
    26281 acgacagtgc ggattcagtt tgctcaagtg aacttagtcc ttgagtaaaa atagatgaga
    26341 aaagcctcca gattggaggc ttttatgcta gactcttatt tctcaacgcg tgatttgttg
    26401 gcgatatcag ctaggatagc ttgaacaaaa ttatcaactg agacagtttg tgtttctttt
    26461 tggccgtagc gacgaacgtt gactgtttcg tcttccattt ctttgtctcc aacaattaat
    26521 tggtaaggaa tcttgctggt ttgtgaagca cggatcttga actgcatttt ttcattgcgc
    26581 tcatctacat ctgcacggac accgcggtca cggagtttct tggctacttc ccaagcgtag
    26641 tccacgtgtt tttcgttaga tactgggatg agggttactt ggtgtggtgc cagccatgtt
    26701 gggaaggccc ccttgtagtt ctcaatcaag atagctgtga agcgttccat agttgagata
    26761 accccacggt ggatcatgac tggacggtga tcttcgccat cagctccgat gtatttgagg
    26821 tcgaagcgtt ctggcaacaa gaaatcaagt tggatagtag aaagggtttc ttcttttcca
    26881 agggcagttt taatctggat atccaatttt ggtccgtaga aggctgcttc accttcggat
    26941 tcaaagtagt ccacgcccat ttcatcaaga gctgcacgaa gcatggtttg ggcattttcc
    27001 cacatctcat cgttatcaaa gtacttatga gtatcttgag ggtcacgaag agagaggcgg
    27061 aagcggtagt cagtcaagtt gaagtcttca taaacatcga taatcaactg aagggcacgt
    27121 tggaattctt cttggatttg ttctggagta acgaataggt gaccgtcgtt gagtgacatt
    27181 tcacgtacac gttgaaggcc agtgagggca ccagattttt cgtaacggtg catcataccg
    27241 atttcagcga tacggattgg caattcacgg taagagtgaa catggtgttt gaaaacttgg
    27301 atgtggtgcg gacagttcat tggacgaagg acaaattctt ccccgtcacc catgtccatg
    27361 gttgggaaca tgtcttcttg gtaatgatcc cagtgaccag aagtcttgta aagctcaaca
    27421 gaagcaagtg gtggagtgta gacgtgttgg tagccagaag ccaactcttt gtttacgatg
    27481 tagtgttcca attcacgacg gatagtcgca ccatttggca accagaatgg caaaccttgt
    27541 cccacttctt gtgaaatcat aaagaggtca agctctttac caagtttacg gtggtcacgt
    27601 tccttagctt cttcacgcat ttgaaggtag tttttcaagt ctttcttgtc aaaccaagct
    27661 gtaccgtaga tacgttgcat catagcgttg tcgctgtttc cacgccagta cgcaccagct
    27721 acatggagaa ggtggaagat ttggatacga cctgttgatg gaacgtgagg tccacggcag
    27781 aggtctacat attcaccctg acgatagata gtcaaaccgc cttcgtcttc tgagtgttct
    27841 tcaatcaatt ccaacttgta agggtcattt ttgaagattt cacgtgcctc gtctttagtc
    27901 acttcttcac gaatagatgg gaagttttct ttgacgattt tttgcatttc ttcttcgata
    27961 cgaggaaggt cttcgttaga gatttgacca gctgtgttgt cagtatcgta gtagaaacca
    28021 tcttcgatgg ctggaccaac tcccaagtga atgtctggga aaagacgacg agctgcttgg
    28081 gcgaacaagt gagctgctga gtgacgcaag attggaaggg catcttcgtg atcaggtgtc
    28141 acaatttcga tgcttccatc ttcagtgata gcgcgagtag tgtcgatgag tttgccgttg
    28201 aatttaccag ccaaggcttt tttagctagg gaattgctga tagattgggc aatttcaaaa
    28261 gttgttacgc cagattcgaa ttcacgaaca gcgccatctg ggaaagtaat gttaatcatg
    28321 atgttctcct tttttattat ttcatagttt ctaagcattg attttttatc agcagactac
    28381 ttccgagtcc taacgttcaa ttgcttttct ttatcagaga ggaagttttc catttccgtc
    28441 agaatgtcta tatccaaacg ttgagaaagt tctaatagcc accagatatt ttctgaaagt
    28501 ttttgttcca gtgtgtagga tgtttcatca tagtagcgtc cttgctttgt catcaccagt
    28561 cattggaaat ttccaatatc attagataaa gccaagaggt cttcttctac cgtccacttg
    28621 aaatcatgat gcttaacttc cagttcgtga taagcttgtc ggattgccca actgcgctcc
    28681 actaattctt gcaactccat aattagtatc ctaataaaaa aatgcgacat cctcgaaagg
    28741 acgtcgcaac gtggttccac cttcatttat gtacctcaaa agagagggac acctctgatc
    28801 ggctctaacg tggccaccgt tttatgtttt cataaaaaac tcaagagtag tatcagttta
    28861 gacttcctat gcgtttccag caaccacgca ctctctagta gaaagggact aagtgacttg
    28921 tctctatgga ttattatagc atgattgtga gatttttcaa ggattttgtg aaagtttttt
    28981 gtttttcatt ttttgtagaa tatgcttgat gctaatacca gaatccatgc ccaccagagc
    29041 aactgtttca tagattagca agtaaattag tataaactca ccaaaggtta tgatagtaaa
    29101 gtaaaagagc agtccgttac caactaacca tcaaagtgag aaacggaaac ggtagctata
    29161 gagtaacgat acaatcaaga ttaccatagg tgtaaagaag agaagattgt ttatatagag
    29221 tcccttgagt gtaagggggt cagaaacaac tagcaagaac aactcataaa gtggccaata
    29281 aaagaataat atgaccagat agtaggggag atgggaatag aatctacgca tgataatcac
    29341 ctcgttttaa aaaaacagac aacttagatc tcttgctatg attattatag catgtttaaa
    29401 acaagaaagt aaatttgttg acaaagaaga tttttctttt cactagaatc atagttagtt
    29461 ttcttggtag aaatattttg ataataatta agcaagacta ttgatattga ttattaagag
    29521 tgtcacaatt gttgtaacta aaatgattac aacaatagag gtataaaaaa tgaaactagc
    29581 agttattgca gcaaatggac aagcggggaa agcaattgtt gaagaagcag tcaaacgagg
    29641 acatgaagta acggctattg ttcgttctga aaacaaaagt caagctgagt ctattattaa
    29701 aaaagattta tttgagttga caaaagatga tcttactgga tttgatgctg ttatttcagc
    29761 gtttggtgct tatacaccag atacgctacc gctccacagc aaatcaatcg aactatttaa
    29821 tcagcttctt gctggaacac agacacgttt tctagttgta gggggagcag gaagtcttta
    29881 tatagatgaa acaaaaacga cacgactttt agatacgtct gattttcctg aagaatttaa
    29941 gtcactagca aaagatcaag cggatgaatt ggatcttctt cgtacaaaaa ataatctcaa
    30001 ctggactttt gtcagtcctg ctgtagattt tattcccgat ggtgaaaaaa caggaaacta
    30061 cattctagca ggagaaattt ttactactaa tgaaaaagga ataagccaga ttagttatgc
    30121 agattatgct attggattgg tagatgaact tgaaaaaggt catcatataa aagaacatat
    30181 ctctttactt gaaaaataat aactatgaga gtattaatgt ttgacagaaa atttaaatct
    30241 tggtaaaata gggattgtcg taaagacaaa taacttcttc ttggttacag gcatgccaac
    30301 ctgtcactcg gatgaagcca aataaaaagg agaaacatca tggcaatctc aaaagagaaa
    30361 aaaaatgaaa tcattgcaca atatgcacgt cacgaaggtg atacaggttc agtagaggtt
    30421 caagttgctg tccttacttg ggaaatcaac caccttaacg aacacatcaa acaacacaaa
    30481 aaagaccacg ctacttaccg tggattgatg aaaaaaatcg gtcgccgtcg taacttgctt
    30541 gcatacttgc gtaaaaacga cgttaaccgt taccgtgagt tgatcaactc tctaggactt
    30601 cgtcgctaat tcaagataca aatgctgtca aaagcacaaa gcaaaaatag gaaaattgac
    30661 gaagaaactt cagtttctag gagattttat cttttttgcc aagtgcttag gccgtgttca
    30721 attgagcata tcttgataat gaagctactc taaattgggt agcttttttg cgttgtcacc
    30781 ttacctcgat atactcaagt ataatctttg gttacggttc ctagcactgt aaggtaaaat
    30841 aaaccagctt ttctcccttc ggggagattt tttttgtttc actgaaagtt tcgtacgatc
    30901 ttcgcctcgt cgcctagtct ataaacgatt tatctagcaa gaatcatgat gctaagggcg
    30961 tcaaaaatcc gtatgaaaat agggaaatga cacagtgttc gatgagcaca aggagtttca
    31021 tctttttcac taggatttta gcccgggctc aaatcagctc tctgacttca gagggctttt
    31081 ttattgaggt tttatcggta acaattttgg agactacaaa aacctcaaac ggtatcagct
    31141 aattacacca taaaggtgcg cagttactcg gcttttcaag ccgagtagct gtatgcaagc
    31201 cccctagaag agcccactct ttacaaagta aagtatagta tgttatactt tacatggaag
    31261 tagtcactga attccagtta gaaattactt tgtaactacg ttttgaggag gagtaaaatg
    31321 ctttcctacg ttcgacatta cccactagcg atagctaaat taatgtgtct gtgctctcct
    31381 aaaatctgct gatttattac tgactaatac aggaggtttt ttttatggga cagacaatca
    31441 tatctgctat tggtgtttat atttccacca gtatcgatta tttaattatt ttaattattt
    31501 tatttgcaca gctatcacag aataaacaga aatggcatat ttatgcgggg caatatctag
    31561 gcacaggctt acttgtaggg gcgagtttag ttgctgctta tgtcgttaat ttcgtgcctg
    31621 aagaatggat ggttggattg cttggtttaa tccctatcta tttagggatt cgctttgcaa
    31681 ttgttggaga agatgcggaa gaagaagagg aagaaattat tgaaagatta gaacaaagca
    31741 aggcaaatca actgttttgg acagttacat tgctgacaat tgcgtctggc ggagataatt
    31801 taggtatcta tataccttat tttgcttcgt tagattggtc acagaccctc gtggccttgc
    31861 ttgtgtttgt aatcggcata attatctttt gcgagattag tagggtgtta tcctctattc
    31921 cgttaatatt cgagacaatt gaaaaatacg agcgaatcat tgtgccctta gtattcattc
    31981 tacttggact atacatcatg tatgaaaatg gcacgataga gacttttctg atcgtgtaga
    32041 tttttttgtt tcactaggat tttagcccga gctcaaatca gctctctgat tttcagaggg
    32101 ctttttcatt gagtataaat ggacaatctt aaagttactc tattgtagag tggcttttga
    32161 tttgattagg agattcttat aaatatagta aaatgaaata agaataggac aaatcgatca
    32221 ggacagtcaa atcgatttct aaaaatgttt tagaagtaga ggtgtactat tctagttcca
    32281 atctactata taaatgaaaa ccttagctgt ttggccaagg ttcatttctt ctatgcaagt
    32341 tcttctcttt tcttatctgg gttccagatg aagcttgcga taaagctaaa gatgatggtt
    32401 aggatagcga ggataatagc aaggatgagg gcagggatgc ggataaacca ccagagtgga
    32461 tttggttttt tatcattgtg ccattgtttc gtttcttcgt ccagacgttg gaattctgtt
    32521 tgaatacgat tggcgactgt ttcaatgcct tcatcattca ttttcttgat atctgagata
    32581 tcgattggat ttccaaagtt catatcgaca cgttcacggc taatcaagcc cttcaaagtc
    32641 atgggaccgg tgtaggtaac cggcatgata cggaccttgg ccattttggc aatcagtgct
    32701 gcgcccccct tgacatcgtt tgagtggcgg ctaccacttg gaaacataat gagagagcgg
    32761 tcactttttt tgagaacgtt gataggatat ttgatggctg aggcgctggg attttcacgg
    32821 tcgatgggaa aggcgccaca catacgaatc caccaaccaa agatacggtt ggtaaagagt
    32881 tctttttttg ccataaagat gaactgtttt ggcttggtcg caaaggccat ataaacagga
    32941 tcccaccagg tacggtgagg cgcaactaaa atataatttt catcttgatt aggaatttta
    33001 tcagtattat gatagtgagc attgccattg atggaccata agagcaatac aactaatcca
    33061 cgcaaataag tataaaacat gcgatctcct tcgattgttt tcttgttatt attatacctt
    33121 atcaaaggag ggctggcaaa cttttccctt gactagatac atatttagga tgaaattaga
    33181 attctgttaa aaaaaatgat ataatagaat ttatggataa aaataagatt atgggattaa
    33241 cccaaagaga agtcaaggaa agacaggctg agggtttggt caatgacttt accgcatcag
    33301 ccagtaccag cacttggcaa atcgttaaac gaaatgtctt tacccttttt aacgctttga
    33361 acttagccat tgctttggct cttgcctttg tgcaggcttg gagcaatctg gtcttctttg
    33421 ctgttatctg ctttaacgct ttttctggga ttgtgaccga gctacgagcc aaacacatgg
    33481 tggacaagct caatctcatg accaaggaaa aggtcaaaac catccgtgat ggtcaggaag
    33541 ttgctcttaa tcctgaagaa ttagtgctag gagatgtcat ttgtttgtct gcaggagagc
    33601 agattcctag tgatgccttg gttttggaag gctttgcgga agtcaatgaa gccatgttaa
    33661 cgggagaaag tgatttggtg caaaaggaag ttgacggctt acttttgtca ggaagtttcc
    33721 tagccagtgg gtcagtttta tctcaagttc accatgtcgg tgcagacaac tatgctgcca
    33781 aactcatgct tgaggctaag accgttaaac ccatcaactc ccgtatcatg aaatcgctgg
    33841 acaagttggc tggttttact gggaagatta tcattccctt tggtctggct ctcttgctgg
    33901 aagccttgct tttaaaaggc ctgcctctca agtcatctgt tgtaaactcg tcgacagctc
    33961 ttttgggaat gttgcctaag ggaattgccc ttttgaccat tacttcgctc ttgactgcag
    34021 ttatcaagct aggtttgaaa aaggtcttgg tgcaggagat gtactctgtt gagaccttgg
    34081 cgcgcgtgga tatgctctgt ctggacaaga cgggtaccat cacccaagga aagatgcagg
    34141 tggaggctgt tcttccgttg acggaaacgt atggtgaaga ggctattgcc agcatcttga
    34201 ctagctacat ggcccatagt gaggataaga atccaactgc ccaagccatt cgccagcgtt
    34261 ttgtgggaga tgttgcttat cctatgattt ccaatcttcc cttctcgagc gaccgcaagt
    34321 ggggggctat ggagttagaa ggcttgggga cagttttctt aggggcacct gagatgttgc
    34381 tggattctga agtcccagaa gccagggagg ccttggagag aggatcacgt gtcttggtct
    34441 tagctctcag tcaggagaaa ttagaccatc acaaaccaca gaaaccatct gatattcagg
    34501 ctctagcctt gctggaaatc ttggacccca ttcgagaggg agcagcagag acgctggact
    34561 atctccgttc tcaggaggta ggactcaaga ttatctctgg tgacaatcca gttacggtgt
    34621 ccagcattgc ccagaaggct ggttttgcgg actatcacaa ctatgtagat tgctcaaaaa
    34681 tcaccgatga ggaattgatg gccatggcgg aggagacagc tattttcgga cgtgtttccc
    34741 ctcatcaaaa gaaactcatc atccaaacgt tgaaaaaagc gggtcataca acggctatga
    34801 caggggacgg ggttaatgat atcttggccc ttcgtgaggc ggattgttct atcgtgatgg
    34861 cggaggggga tccagcaacc cgtcagattg ccaatctggt tctcttaaac tcagacttta
    34921 atgatgttcc tgagattctc ttcgagggtc gtcgcgtggt caataacatt gcccacatcg
    34981 ccccgatttt cttgataaag accatctatt ccttcctgtt agcagtcatc tgtattgcca
    35041 gtgctttact aggtcggtca gagtggattt tgattttccc cttcattccg atccagatta
    35101 ccatgattga ccagtttgtg gaaggtttcc caccattcgt tttgactttt gagcgaaata
    35161 tcaaacctgt cgagccaaac ttcctcagaa gatccatgct tcgtgcccta ccaagtgccc
    35221 tcatggtcgt gtttagcgtt ctttttgtga aaatctttgg aacgagtcaa ggttggtctg
    35281 agttagaaat ctcaactctc ctctattatc tcttggggtc aattggtttc ttatccgtat
    35341 ttagagcctg catgccattc actctatggc gagtcctctt gattgtctgg tcagtaggag
    35401 gcttcctagc cacagctctc ttcccaagaa tccaaaaact gcttgaaatt tcaaccttga
    35461 cagaacaaac gttgcctgtt tatggtgtca tgatgttggt ctttaccgtg attttcatcc
    35521 tgactagtcg ctatcaagct agaaaataaa gaaagactgc aatctgtgga ttgcagtttt
    35581 tttaggtaca agattgccag ccgaaatgtg gtataataag aggtaataga gtttggaaag
    35641 tgagagaaaa tgatttcaaa gagattagaa ttggtagctt cctttgtgtc acagggggct
    35701 attttactag atgtgggaag tgaccatgct tatctgccta tcgagttggt tgagagaggc
    35761 caaatcaaaa gcgctattgc aggtgaggtg gtggaaggtc cctatcagtc tgcggttaaa
    35821 aatgttgagg ctcacggcct aaaggagaaa atccaagtcc gtttagccaa tggcttggca
    35881 gcttttgaag agactgacca agtgtctgtc attaccattg ctggcatggg tggtcgtttg
    35941 attgctagga ttttagaaga aggtttgggg aagttagcta atgtagagcg tttgatcctc
    36001 cagcccaata atcgtgaaga cgacttgcgt atctggctac aggatcatgg attccagatt
    36061 gtagcagaaa gcatcttaga agaagctgga aagttttatg agattttggt ggtggaagca
    36121 ggacaaatga agctatcagc cagtgatgtt cgctttggtc ccttcttgtc caaagaagtc
    36181 agtccagtat ttgtccaaaa atggcaaaaa gaagctgaga agctagagtt cgccctcgga
    36241 caaatcccag aaaaaaatct ggaagaacgt caagttctag tagataagat tcaagctatc
    36301 aaggaggtgc cccatgttag caagtgaagt gatccaagct tatgaagcct tttgccctca
    36361 ggaattttct atggagggag acagccgtgg tctgcaaatt ggcactttag acaagggtat
    36421 ccaaagggtc atggttgccc tcgatattcg tgaagagaca gtggcagagg ccattgaaaa
    36481 gggtgtggac ttgattatcg tcaagcacgc gcctatcttt cgtcctatca aggacttgct
    36541 tgccagccgt ccgcaaaatc agatttacat cgacctgatt aagcatgata tcgcagttta
    36601 tgtcagccat accaatattg atatcgttga aaatgggctc aatgactggt tttgtcagat
    36661 gctaggaatc gaggagacga cttatctgca ggaaacaggt ccagaacgtg gaattggacg
    36721 tattgggaat attcagcctc agacattttg ggaattggcc caacaggtca agcaagtctt
    36781 tgacctagat agccttcgaa tggtgcatta tcaagagaat gatttgcaga agcctatttc
    36841 aagagtagca atttgtggtg gaagcgggca gtctttctat aaggatgctt tggcaaaggg
    36901 ggcagatgtc tatatcactg gcgacatcta ctaccatact gctcaggata tgctgtctga
    36961 tggcttgtta gcattggatc caggtcacta tatcgaagtg ctttttgtgg aaaaaatcgc
    37021 agcactcctt actcaatgga aagagaaaaa aggctgggaa ctagagattt tacctagtca
    37081 agcatcgacc aatcctttcc gtcatatcta gttagaaagt gaagacaatg aaaaaagttg
    37141 ccattattgg agcaggaatt gtgggagcaa cagctgccta ctacctctcg agagaaagtg
    37201 acctagaggt gaccgttttt gaccatgagc aaggtcaagc caccaaggcc gcagcaggaa
    37261 ttatcagtcc ttggttttcc aaacgccgta ataaagcctg gtataagatg gcgcgcttgg
    37321 gggctgattt ttatgtggat ttattagctg atttagagaa atcaggacaa gaaatcgact
    37381 tttaccagcg ttcgggagtc tttctcttga aaaaggatga atccaagttg gaagaactct
    37441 atcaactggc tctccagcgc agagaagaat ctcccttgat aggccagtta gccattctgg
    37501 accaagcccc agctaatgaa ttattccctg gcttgcaggg attcgacaac ttgctctatg
    37561 cttctggtgg agcgagagta gatggtcacc tcttagtaac tcgtttgctg gaagccagtc
    37621 aggtcaagtt ggtcaaagaa aaagtgactc tgacactctt atcatcaggc taccagattg
    37681 gcgaagaggt gtttgatcag gttattttgg caacgggagc ttggttgggg gacatgttag
    37741 agcctttagg ttatgaagtg gatgtccgtc ctcaaaaagg acaactacga gattatcagc
    37801 ttgcccaaga catggaagat taccctgttg tcatgccaga aggggagtgg gatttgattc
    37861 cctttgcagg tgggaaatta tccttgggcg ctacccatga aaatgacatg ggatttgatt
    37921 tgacggtaga tgaacccttg ctccaacaaa tggaggaggc ggccttgcct cattacccag
    37981 ttttagctag agtgacttca agggctgagc gtgtgggaat ccgtgcctat accagtgatt
    38041 tctctccctt ctttgggcag gtgccagaat tggcaggtgt ctatgcagcc agtggactag
    38101 gttcatcagg cctcacaact ggtcctatca ttggttacca tctagcccaa ctgatccaag
    38161 acaaggagtt gaccttggac cctctaaatt acccaattga aaactatgtc aaacgagtaa
    38221 aaagcgaata atactcaatg aaaatcaaag aacaaactag gaaactagcc gcgggttact
    38281 caaagcactg ctttgaggtt gtggatagaa ctgacgaagt cagctcaaaa cactgttttg
    38341 aggttgtgga tagaactgac gaagtcagta accataccca tggcaaggcg acgttgacgt
    38401 ggtttgaatt ggattttcga agagtataag cattttactg aaattttatc aggtagttta
    38461 ggatggcaaa tgacattccc tgtcaaaaat ggtaaaataa gaaaaaatga tctgagaatc
    38521 gaggaaaaaa gatgcaagaa aagattttgg taactggtgg tgccggtttt attggaaccc
    38581 acactgttat tgaattgatc caagcaggcc atcaagttgt tgtggtggat aatcttgtca
    38641 atagcaatcg taagagttta gaagttgttg aaagaatcac aggagttgag attcctttct
    38701 atgaggcaga tattcgtgac acagataccc tcagagatat tttcaagcag gaagaaccga
    38761 ctggtgtcat tcactttgct ggtttgaagg ctgttggcga atcaacacgt atccctcttg
    38821 cctactatga caacaatatc gctggaactg tcagcctttt gaaagccatg gaagaaaaca
    38881 actgtaaaaa catcatcttc agttcttctg cgacagttta cggggatccg cacacagtgc
    38941 ccatcttgga agatttccca ctttcagtga caaacccata cggtcgtacc aagctcatgc
    39001 tagaggaaat tttgaccgat atttacaaag cagactcaga atggaatgtt gtcttgcttc
    39061 gttactttaa cccaatcgga gcccatgaga gtggtgattt gggagaaaat ccaaacggta
    39121 ttccaaacaa tctcttgcca tatgtgactc aagtagccgt tggaaaatta gagcaagtgc
    39181 aagtgtttgg agacgattac gatacggaag atggaacagg tgttcgtgac tatatccacg
    39241 ttgtcgattt ggctaagggt cacgttgcag ctttgaaaaa aatccaaaaa ggttcaggac
    39301 taaacgttta taaccttgga actggtaaag gttactcagt tcttgaaatt atccaaaaca
    39361 tggaaaaagc ggtgggacgt cctattcctt accgcatcgt agaacgtcgc ccaggtgata
    39421 tcgctgcctg ctactcagac ccagcaaaag ctaaagcaga actcggttgg gaagcagaac
    39481 tcgacatcac ccaaatgtgt gaagacgcat ggcgttggca aagcaagcat ccaaatggat
    39541 ttgaagacta agatgatgat ttcaatcatc gtcccttgtt taaacgaaga ggaagtactt
    39601 cctctttttt atcaggctct ggaagcttta cttccagatt tggaaacaga aatcgagtat
    39661 gtctttgtcg atgatggatc aagtgatggg accttggaac tcttaaaggc ctatcgggag
    39721 caaaatccgg cagtccatta tatttctttc tctcgaaatt ttggcaaaga agcagccctt
    39781 tatgcaggct tgcaatatgc gacaggagat ttggtggtgg tgatggatgc agacctccaa
    39841 gatcctccta gtatgttgtt tgagatgaaa aatgtactag acaaaaatgt agacttggac
    39901 tgcgttggga cacggagaac tagtcgggag ggagaaccct tctttcgcag tttctctgct
    39961 gttctctttt atcgcctcat gcaaaaaatc agcccagtag ctctgccgtc gggtgtccgt
    40021 gattttcgta tgatgagaag gtctgtagtc gatgccattt taagcttgac cgagtccaat
    40081 cgtttttcaa aggggctctt cgcctgggtg ggtttcaaaa cctactattt ggactatcca
    40141 aatgtcgaaa ggcaggctgg caagacaagt tggagtttta ggcaactctt tttctactcc
    40201 attgaaggga ttattaattt ttcagatttt cccttgatta tagcctttgt agctggtctc
    40261 ctatcttgtt ttctttctct gctgatgacc ttttttgttg tggttcggac cctcattttg
    40321 ggcaatccga catctggttg gacctctctg atggctgtta ttctctttct tggaggcatt
    40381 caactcttga ccattgggat tctcggcaag tatatcagta agatttattt agagactaaa
    40441 aaaagaccac tttatcttat caaagaaaaa agtgaccttc ctgattttac agaaaaaaat
    40501 aaagtgaaaa gactataatt ttacatggaa atgtgctaaa ctagagggag tggattatcg
    40561 ccattgattt aggcttcctg gtttccaatc agggcgcgag ttgggcaatt tttaacagcc
    40621 tctaagacat cctgactagg agaaatttct ttttccagtt ggtcagggtc atcgtaaaaa
    40681 cgcacgattc cattatcgtg gtaatcaaat aaatcagaat aagtttggca aagcccacag
    40741 gcgatacatc gttcaggtat aagtgtgatt ttcatgttca tatttatatt gtaataagaa
    40801 aagtaaaaaa aaacaaggag taaggtatgg caaaagaacc gtggcaagaa gatatctatg
    40861 atcaagaaga atcaagagca gagcgtcggc atcgaaacca cggaggggcg gataggatgg
    40921 ctaatcgtat tttgacgatc ctagctagta ttttctttgt aattgtggtg gtgatggtca
    40981 tcgttctcat ctatctatca tcggggggga gtaatcgcac agcagcctta aaagactttc
    41041 atgattctga tgcaagtgta gtacaaatct catcttcaag cagttctcag cctgagcaga
    41101 gttcagagcc agaatctact tctagtagtt cagaagaagc tgctaatcct gaaggaacga
    41161 ttaaagttct cgcaggagaa ggggaagcag ctattgccgc tcgtgcagga atctccattg
    41221 ctcagttaga ggccttgaat cctgggcaca tggctacagg atcttggttt gctaatccag
    41281 gtgatgttat aaaaataaaa taggagccga tatgaaaaca attcaaattg ctattgatgg
    41341 tcctgcttcc agcggtaaga gtacggtcgc aaagattatt gctaaggatt ttggattcac
    41401 ctaccttgat acaggagcta tgtatcgtgc agcgacctat atggctctta agaaccaatt
    41461 aggagttgaa gaagtcgaag cccttctagc cttgttggac cagcatccaa tcagctttgg
    41521 acgttcagaa actggagacc agcttgtttt tgtaggagat gtggatatta cccatcctat
    41581 ccgtgaaaat gaagtgacca atcatgtttc tgctattgca gcaattcctg aagtgcgtga
    41641 gaaactggtt tctctccaac aagaaattgc ccagcaaggc gggattgtta tggatggtcg
    41701 cgatattgga actgttgtat tgccgcaagc agaattgaaa attttcctag tagcttctgt
    41761 tgatgagaga gcagagcgtc gttacaagga aaatattgcc aagggaattg aaacagacct
    41821 tgaaacccta aaaaaggaaa ttgctgcgcg tgactacaag gatagtcatc gtgagacttc
    41881 tcctctcaaa caagcagagg atgctgtcta ccttgataca actggtttga acattcaaga
    41941 agtagttgaa aaaatcaaag cagaagctga aaaaagaatg taaatgtaga aaagccgata
    42001 gattgatatc ggttttttct aaatttgtca aaatgctgat tttagggtat aatagttgct
    42061 gttcgagaaa ttttgatttt caaagaatag tgaatgatga taaggagaaa tcatgaacaa
    42121 tttaccaaat tgtccaaaat gtaactcaga gtatgtctac gaagacggtg ccctactggt
    42181 ttgcccagag tgtgctcatg agtggaatcc tgctgaagtt gcagaagtag aagaaggtct
    42241 tgtcgctatc gatgccaacg gaaataaatt gactgatggt gatacagtaa ctctcatcaa
    42301 ggacttgaaa gtaaaaggtg cgccaaaaga tttgaaacaa gggacgcgcg tgaaaaatat
    42361 ccgcatcgta gaaggcgatc acaatatcga ctgtaagatt gatggttttg gtgccatgaa
    42421 acttaaatca gagtttgtga ggaagattta agcatgtcaa aacactataa acttgtattt
    42481 tatagccgta tcttcttgtt tctagcggct tttacgggag tttatcttga aattactagg
    42541 catggtggtt ttgggatgct tctctattac acggttctgt ccaacctctt ggtaactatt
    42601 tttacccttt atcttctaaa ggttatgagc cgtgtaggtg aaaattggca aaggccaagt
    42661 ctcttgcgct taaaaggtgg ggtcaccatg agtatcatga ttacctgtgt gatttaccat
    42721 ttcctcttgg cgcccattgc gactaatttc tataccctag aaaatttcct ttgccactat
    42781 atcgttccca tctggttttt agcggatacc ctcttttttg acaaacaggg tcaatacaag
    42841 atttgggatc cagcagtgtg gaccatttta ccctttctgt atatgatgtt tgctcttttt
    42901 aatggcttgg ttctaaaact caatattcca aatgccaagg ataatccttt cccttacttc
    42961 tttttgaatg tgaacaaggg ttggaatgtt gtgtttaagt ggtgtctgat tatctttgtt
    43021 gcctatatgg tagcaggatt tattttctac tttatcaagc aaatcaagag aaagtcatcc
    43081 taatactctt cgaaaatctc ttcaaaccac gttagtttcc atctgcaacc tcaaaacact
    43141 gttttgaaca acctgcggct agctttctag tttgctcttt gattttcatt gagtatgaga
    43201 tacaagggat tcattttcga atttaagaag gagtctacaa accaatgagg cttcttcttt
    43261 tcttgcttat ttgataacta tcaaaaaagt agaagattaa gagaaatata gaaagagatt
    43321 tcatgaaaca atttttagaa cgggccagca ttttggctct ctccctcgtt ttgattacct
    43381 ccttttccat ttcgagtgcc ctaccagcca tgtttgacta ttatcagggt tattctaagg
    43441 aacaaattga gctcttggtg agcttgcctt cctttggaat catgatgatg ttactgctaa
    43501 atggtttctt agaaaaaata tttcctgagc gcttacagat tagtttgggc ttgctgattt
    43561 tatcattgag cggtacagct cccttctggt accaagccta tccctttgtc tttggaacac
    43621 ggcttctctt tggtttgggt cttgggatga tcaatgccaa ggccatttct attatcagtg
    43681 aacgctacca aggaaaaagg cgaattcaga tgttagggct acgcgcttct gcagaggtcg
    43741 ttggagcttc tctcattacc ttggccgtcg gtcagttgtt ggcctttggt tggacagcta
    43801 tctttctagc ctatagtgct ggatttttgg tgatgcccct ttatctgctc tttgtccctt
    43861 atggaaaatc aaagaaagaa gtcaagaaaa gagcgaagga agcaagtcgt ttaactcgag
    43921 aaatgaaagg cttgattttt accttagcta tcgaagcggc agttgtagtt tgtaccaata
    43981 cagctattac catccgtatt ccaagtttga tggtggaaag aggattgggg gatgcccagt
    44041 tatctagttt tgttcttagt atcatgcagt tgatcgggat tgtggctggg gtgagttttt
    44101 ctttcttgat ttctatcttt aaagagaaac tgctcctctg gtctggtatt acctttggct
    44161 tggggcaaat cgtgattgcc ttgtcttcat ccttgtgggt ggtagtagca ggaagtgttc
    44221 tggctggatt tgcctatagt gtagtcttga cgacggtctt tcaacttgtc tctgaacgaa
    44281 ttccagctaa actcctcaat caagcaactt catttgctgt attaggctgt agtttcggag
    44341 cctttacgac cccatttgtt ctaggtgcaa ttggcttact aactcacaat gggatgttgg
    44401 tctttagtat cttaggaggt tggttgattg taatctctat ctttgtcatg tacctacttc
    44461 agaagagagc ttaggattga ttcctaagtt tttcttttga tactcaatga aaatcaaaga
    44521 gcatagttga ttgagtttgg aatagtacgc tgtagctgct aaaatatttc tagaaattaa
    44581 tttgactttt ctaatagagt tattcatatc ttatttcaat ctactataga aagctagccg
    44641 caggttgctc aaaatagtgt tttgaggttg cagatggaaa ctgacgtggt ttgaagagat
    44701 tttcgaagag tatgagattt ttatacccat acaatatttg ttttaggtcc ttgtttacag
    44761 actaatttct tgataaaata gaggttatga cgagatataa agcaactatt tcctatgatg
    44821 gttatgcctt tgctggcttt cagcgccagt ctcatgcgcg tagcgttcag gaagaaattg
    44881 aaaaaacctt gaccagatta aataaagggc aaaccattac tgttcacggt gctggtagga
    44941 cagatagtgg ggttcatgcc ctgggacagg tcattcattt tgacctgcct tatcagatgg
    45001 atgaggagaa actccgtttt gccttggata cccagtctcc tgaagatatt gatgtgattt
    45061 cgattgagct tgtggcagat gattttcatt gccgttatgc caaacatagc aagacctatg
    45121 agtttattgt ggatagagga cgtcccaaaa atcctatgcg ccgtcactat gccacccact
    45181 ttccctaccc actcgatgtg gaacgaatgc agattgcaat caaaaagcta gagggaaccc
    45241 atgattttac cggttttaca gcctctggga ctagtgtaga ggataaggtt cgcaccatca
    45301 cagaagctag tttaatagtc gatgagacag gacaattttt gacctttacc ttttcaggaa
    45361 atggtttctt gtataaacag attcgcaata tggtggggac tcttctcaaa atcggtaaca
    45421 accgcatgcc agtagagcag attgatctca tcttggagaa gaaggacagg caacttgcag
    45481 gtcccactgc agcaccaaat ggtttgtatt taaaggagat tcgttatgaa gaataatcgt
    45541 attttagcac tttctggaaa tgatattttt agtggtggtg gactgtcagc tgatttggct
    45601 acctatacct tgaacggctt gcatgggttt gtagcagtga cttgtttgac agccttgaca
    45661 gaaaaaggat ttgaagtctt tccaactgat gataccattt ttcaacatga attagatagc
    45721 ttacgtgatg tggaatttgg gggaattaag attggtcttc tccctactgt cagtgtggct
    45781 gagaaggcct tggactttat caaacaacgc ccaggagtac ctgtggtgtt ggatcctgtc
    45841 ttggtctgca aggaaacgca tgatgtagct gtcagtgagc tctgccaaga gttgattcgc
    45901 tttttccctt atgtcagtgt gattacgcct aatctcccag aagcagaatt attatccggt
    45961 caggaaatta aaaccttgga agacatgaaa actgcagcgc agaaattgca tgatttagga
    46021 gcgccagcag tcattatcaa gggaggcaat cgtcttagtc aggacaaggc tgtggatgtc
    46081 ttttatgatg gacagacctt tactatccta gaaaatccag ttatccaagg ccaaaatgct
    46141 ggtgcaggtt gtacctttgc ctctagcatt gccagtcact tgattaaagg tgataaactt
    46201 ttgccagcag tagaaagctc taaggctttc gtttatcgtg ctattgcaca agcagatcag
    46261 tatggagtaa gacaatatga agcaaacaaa aacaactaaa atcgcccttg tatccctatt
    46321 aaccgccctt tctgtggttc taggttattt cttaaaaatc ccaacaccta caggaattct
    46381 aactctttta gatgctggtg tcttctttgc ggccttttac tttggtagtc gtgaaggagc
    46441 ggtagtcgga ggactagcaa gtttcttgat tgacctctta tcaggctacc ctcagtggat
    46501 gttctttagc ttggtcaacc atggcttgca gggatttttc gcaggattta aaggaaaaag
    46561 tcagtggtta ggccttattt tagcaactat tgccatggta ggaggctacg ccttgggttc
    46621 tactttgatg aatggctggg cagcagccct cccagaaatt ctaccaaatt tcatgcaaaa
    46681 tatggtaggg atgattgtag gatttattct tagtcaaagt atcaagaaga ttaagtaata
    46741 ctcttcgaaa atctcttcaa accacgtcag cttccatctg caacctcaaa acactgtttt
    46801 gagcagcctg aggctagctt tctagtttgc actttgattt tcattgagta taaagaggtt
    46861 gagtaaaaag tatttcaaat aagaaaaacg catagtatca ggtgttgaat gaactgcccc
    46921 ccaaaagtta gacagaaaaa atctaacttt tggggt
//
LOCUS       DBEJHE010000016        45142 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC4 isolate 671759
            SAMN38261586-rid24793303.denovo.16, whole genome shotgun sequence.
ACCESSION   DBEJHE010000016 DBEJHE010000000
VERSION     DBEJHE010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261586
            Sequence Read Archive: SRR26833752
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 45142)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45142)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576136.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576136.1
            Genome Coverage       :: 109x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 19:48:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,067
            CDSs (total)                      :: 2,029
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 131
            CDSs (without protein)            :: 131
            Pseudo Genes (ambiguous residues) :: 0 of 131
            Pseudo Genes (frameshifted)       :: 64 of 131
            Pseudo Genes (incomplete)         :: 59 of 131
            Pseudo Genes (internal stop)      :: 46 of 131
            Pseudo Genes (multiple problems)  :: 32 of 131
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45142
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261586-rid24793303.denovo.16"
                     /strain="GPSC4"
                     /isolate="671759"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            <1..210
                     /locus_tag="ACL3EZ_001175"
     CDS             <1..210
                     /locus_tag="ACL3EZ_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HGR0392751.1"
                     /translation="WKVRNIEAEAIRRNCERGAIFSGKIKHHEDSQFKGDHYVECYAV
                     LDNTVIARDRITVPIDPLCGKDFIE"
     gene            554..1888
                     /gene="trmFO"
                     /locus_tag="ACL3EZ_001176"
     CDS             554..1888
                     /gene="trmFO"
                     /locus_tag="ACL3EZ_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HGR0392752.1"
                     /translation="MSQSYINVIGAGLAGSEAAYQIAERGIPVKLYEMRGVKSTPQHK
                     TDNFAELVCSNSLRGDALTNAVGLLKEEMRRLGSVILESAEATRVPAGGALAVDRDGF
                     SQMVTEKVVNHPLIEVVRDEITELPTDVITVVATGPLTSDALAEKIHALNNGDGFYFY
                     DAAAPIIDVNTIDMSKVYLKSRYDKGEAAYLNAPMTKQEFMDFHEALVNAEEAPLNSF
                     EKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYTGPRDGEFKTPYAVVQLRQ
                     DNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLLEQT
                     YRSKKQPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKEESEVIFPETTAIGSLAH
                     YITHADSKHFQPMNVNFGIIKELEGERIRDKKARYEKIAERALADLEEFLTV"
     gene            1972..2709
                     /gene="pyrH"
                     /locus_tag="ACL3EZ_001177"
     CDS             1972..2709
                     /gene="pyrH"
                     /locus_tag="ACL3EZ_001177"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0033862 - UMP kinase activity [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HGR0392753.1"
                     /translation="MANPKYKRILIKLSGEALAGERGVGIDIQTVQTIAKEIQEVHSL
                     GIEIALVIGGGNLWRGEPAAEAGMDRVQADYTGMLGTVMNALVMADSLQQVGVDTRVQ
                     TAIAMQQVAEPYVRGRALRHLEKGRIVIFGAGIGSPYFSTDTTAALRAAEIEADAILM
                     AKNGVDGVYNADPKKDKTAVKFEELTHRDVINKGLRIMDSTASTLSMDNDIDLVVFNM
                     NQSGNIKRVVFGENIGTTVSNNIEEKE"
     gene            2718..3275
                     /gene="frr"
                     /locus_tag="ACL3EZ_001178"
     CDS             2718..3275
                     /gene="frr"
                     /locus_tag="ACL3EZ_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008135 - translation factor activity, RNA
                     binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HGR0392754.1"
                     /translation="MANVIIEKAKERMTQSHQSLAREFGGIRAGRANASLLDRVHVEY
                     YGVETPLNQIASITIPEARVLLVTPFDKSSLKDIERALNASDLGITPANDGSVIRLVI
                     PALTEETRRDLAKEVKKVGENAKVAVRNIRRDAMDEAKKQEKAKEITEDELKTLEKDI
                     QKVTDDAVKHIDDMTANKEKELLEV"
     gene            3335..4189
                     /gene="cvfB"
                     /locus_tag="ACL3EZ_001179"
     CDS             3335..4189
                     /gene="cvfB"
                     /locus_tag="ACL3EZ_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding virulence regulatory protein CvfB"
                     /protein_id="HGR0392755.1"
                     /translation="MNTNLASFIVGLIIDENDRFYFVQKDGQTYALAKEEGQHTVGDT
                     VKGFAYTDMKQKLRLTTLEVTATQDQFGWGRVTEVRKDLGVFVDTGLPDKEIVVSLDI
                     LPVLKELWPKKGDQLYIRLEVDKKDRIWGLLAYQEDFQRLARPAYNNMQNQNWPAIVY
                     RLKLSGTFVYLPENNMLGFIHPSERYAEPRLGQVLDARVIGFREVDRTLNLSLKPRSF
                     EMLENDAQMILTYLESNGGFMTLNDKSSPDDIKATFGISKGQFKKALGGLMKAGKIKQ
                     DQFGTELI"
     gene            4198..4413
                     /locus_tag="ACL3EZ_001180"
     CDS             4198..4413
                     /locus_tag="ACL3EZ_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HGR0392756.1"
                     /translation="MRKSFYTWLMTERNPKSNSPKAILADLAFEEAAFPKHTDDFDEV
                     SRFLEEHASFSFNLGDFDSIWQEYLEH"
     gene            4499..5467
                     /locus_tag="ACL3EZ_001181"
     CDS             4499..5467
                     /locus_tag="ACL3EZ_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HGR0392757.1"
                     /translation="MKEHSIDIQLSHPDDLFHLFGSNERHLRLMEEELDVVIHARTEI
                     VQVLGEESACEEARQVIQALMVLVNRGMTVGTPDVVTAISMVKNDEIDKFVALYEEEI
                     IKDNTGKPIRVKTLGQKLYVDSVKQHDVTFGIGPAGTGKTFLAVTLAVTALKRGQVKR
                     IILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYQILGKDQTTRLMEREIIEIAP
                     LAYMRGRTLDDAFVILDEAQNTTIMQMKMFLTRLGFHSKMIVNGDISQIDLPRNVKSG
                     LIDAQEKLKNIHQIDFVHFSAKDVVRHPVVAQIIRAYEYSTEVAHD"
     gene            5660..6160
                     /locus_tag="ACL3EZ_001182"
     CDS             5660..6160
                     /locus_tag="ACL3EZ_001182"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR0392758.1"
                     /translation="MIDQLSKYYSCRILTEKDIPSILSLYESNPLYFQHCPPEPNFAT
                     VKEDMLCLPEGKAKADKFFVGFWNGSDLVAVIDFVYAHPDEETVFIGLFMVDQAYQRK
                     GIGSHIVTEALAYFAKNFRKARLAYVKGNPQSQHFWEKQGFKSIGCEVKQELYTVVIA
                     EQSLED"
     gene            6163..6489
                     /locus_tag="ACL3EZ_001183"
                     /pseudo
     CDS             6163..6489
                     /locus_tag="ACL3EZ_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003032802.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TfoX/Sxy family protein"
     gene            complement(6790..7901)
                     /gene="ald"
                     /locus_tag="ACL3EZ_001184"
                     /pseudo
     CDS             complement(6790..7901)
                     /gene="ald"
                     /locus_tag="ACL3EZ_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003018852.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0000286 - alanine dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0042853 - L-alanine catabolic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alanine dehydrogenase"
     gene            8078..8647
                     /locus_tag="ACL3EZ_001185"
     CDS             8078..8647
                     /locus_tag="ACL3EZ_001185"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR0392759.1"
                     /translation="MESIFVKFAQYPSIETERLLLRPVTLDDAEAMFDYASDKGNTRY
                     TFPTNQSLEETKNNIAQFYLANPLGRWGIELKDNGKFIGTIDLHKIDPVLKKAAIGYI
                     INKKYWNQGLTPETNRAVIELAFEKIGMNKLVALYDKDNSASGKVMEKSGMRFSHAEP
                     YACMDQHEKGRIVTRVHYVLTKEDYFANK"
     gene            8715..9365
                     /locus_tag="ACL3EZ_001186"
     CDS             8715..9365
                     /locus_tag="ACL3EZ_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComEA family DNA-binding protein"
                     /protein_id="HGR0392760.1"
                     /translation="MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNLQ
                     AEVAAVSKDLVSEKEVNKEEKEEPLEQDLITVDVKGAVKSPGIYDLPVGSRVNDAVQK
                     AGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGSGTASSISKEKKVNLNKA
                     SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGGKTIEKLKDYVTVD"
     gene            9349..11589
                     /locus_tag="ACL3EZ_001187"
     CDS             9349..11589
                     /locus_tag="ACL3EZ_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0009290 - DNA import into cell involved in
                     transformation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HGR0392761.1"
                     /translation="MLQWIKNFSIPLIYLSFLLLWLYYAIFSASYLALLGFVFLLVCL
                     FIQFPWKSAGKVLIICGIFGFWFVFQNWQQSQASQNLADSVERVRILPDTIKVNGDSL
                     SFRGKSNGRAFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFNYQAY
                     LKTQGIYQTLNIKKIQSLQKIGSWDIGENLSSLRRKAVVWIKTHFPDPMRNYMTGLLL
                     GHLDTDFEEMNELYSSLGIIHLFALSGMQVGFFMNGFKKLLLRLGLTQEKLKWLTYPF
                     SLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFIVMPNFFLTAGGVLSC
                     AYAFILTMTSKEGEGLKAVTSESLVISLGILPILSFYFAEFQPLSILLTFVFSFLFDL
                     TFLPLLSILFVLSFLYPVIQLNFIFEWLEGIIRLVSQVTSRPLVFGQPNAWFLILLLI
                     SLALVYDLRKNIKKLTVLCLLITGLFLLTKHPLENEITMLDVGQGESIFLRDVTGKTI
                     LIDVGGKAESYKKIEKWQEKMTTSNAQRTLIPYLKSRGVAKIDQLILTNTDKEHVGDL
                     LEVTKAFHVGEILVSKGSLKQKQFVVELQATQTKVRSMTVGENLPIFGSQLEVLSPRK
                     MGDGGHDDTLVLYGKFLDKQFLFTGNLEEKGEKDLLKHYPDLKVNVLKASQHGNKKSS
                     SPAFLEKLKPELTLISVGKSNRMKLPHQETLTRLEGINSKVYRTDQQGAIRFKGWNSW
                     KIESVR"
     gene            11731..11955
                     /locus_tag="ACL3EZ_001188"
     CDS             11731..11955
                     /locus_tag="ACL3EZ_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0392762.1"
                     /translation="MIIGLFQSSISAVTVTKSYKYDWNTVWEYSTNYHDHQYAWIPSW
                     SRYYSYSEYPVGSGWNYARYEVINYYTGGY"
     gene            11987..12574
                     /locus_tag="ACL3EZ_001189"
     CDS             11987..12574
                     /locus_tag="ACL3EZ_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000939891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGR0392763.1"
                     /translation="MLRLTHVTLKTRQVILQDADFTFKKGRVYGLLAINGSGKTTLFR
                     AMSKLLPLSSGHIAVPPSLFYYESVEWLDGNLSGMDYLRLIKNIWKSDLNLRDEIAYW
                     EMADYISLPIRKYSLGMKQRLVIAMYFLSQAKCWLMDEITNGLDEYYRQKFFDRLAQI
                     DRQEQLVLLSSHYKEELVDICDRVVTIHQGQIEEV"
     gene            12578..13759
                     /locus_tag="ACL3EZ_001190"
     CDS             12578..13759
                     /locus_tag="ACL3EZ_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0392764.1"
                     /translation="MKDVSLFLLKKVFKSRLNWIILLLFASVLGVTFYLNSQTANSHS
                     LESRLESRIAANERAINENEEKLSQMSDTSSEEYQFAKNNLDVQKNLLTRKTEILTLL
                     KEGRWKEAYYLQWQDEEKNYEFVSNDPTASSGLKMGVDRERKIYQALYPLNIKAHTLE
                     FPTHGIDQIVWILEVIIPSLFVVAIIFMLTQLFAERYQNHLDTAHLYPVSKVTFAISS
                     LGVVVGYVTVLFIGICGFSFLVGSLISGFGQLDYPYPIYSLVNQEVTIGKIQDVLFPG
                     LLLAFLAFIVIVEVVYLIAYFFKQKMPVLFLSLIGIVGLLFGIQTIQPLQRIAHLIPF
                     TYLRSVEILSGRLSKQIDNVDLNWSMGMVLLPCLIILLLVGILFIESWGSSRKKEVFK
                     V"
     misc_feature    13919..14050
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            14066..14596
                     /gene="infC"
                     /locus_tag="ACL3EZ_001191"
     CDS             14066..14596
                     /gene="infC"
                     /locus_tag="ACL3EZ_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HGR0392765.1"
                     /translation="MKTIAKQDLFINDEIRVREVRLIGLEGEQLGIKPLSEAQALADN
                     ANVDLVLIQPQAKPPVAKIMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPTIDKGD
                     FDTKLRNARKFLEKGNKVKVSIRFKGRMITHKEIGAKVLAEFAEATQDIAIIEQRAKM
                     DGRQMFMQLAPATDKK"
     gene            14629..14829
                     /gene="rpmI"
                     /locus_tag="ACL3EZ_001192"
     CDS             14629..14829
                     /gene="rpmI"
                     /locus_tag="ACL3EZ_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HGR0392766.1"
                     /translation="MPKQKTHRASAKRFKRTGSGGLKRFRAYTSHRFHGKTKKQRRHL
                     RKASMVHSGDYKRIKAMLTRLK"
     gene            14881..15240
                     /gene="rplT"
                     /locus_tag="ACL3EZ_001193"
     CDS             14881..15240
                     /gene="rplT"
                     /locus_tag="ACL3EZ_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HGR0392767.1"
                     /translation="MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYY
                     YAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVND
                     AVAFTALADAAKAKLGK"
     gene            15298..15678
                     /locus_tag="ACL3EZ_001194"
     CDS             15298..15678
                     /locus_tag="ACL3EZ_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HGR0392768.1"
                     /translation="MASKMLHTCLRVENLEKSIAFYQDAFGFKELRRRDFPDHAFTIV
                     YLGLEGDDYELELTYNYDHGPYVVGDGFAHIALSTPDLEALHQEHSAKGYEVTEPNGL
                     PGTTPNYYFVKDPDGYKVEVIREK"
     gene            15928..16728
                     /locus_tag="ACL3EZ_001195"
     CDS             15928..16728
                     /locus_tag="ACL3EZ_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HGR0392769.1"
                     /translation="MNLTCKKRLGVIRLETMKVVAQEEIAPAIFELVLEGEMVEAMRA
                     GQFLHLRVPDDAHLLRRPISISSIDKANKQCHLIYRIEGAGTAIFSTLSQGDTLDVMG
                     PQGNGFDLSDLDEQNQVLLVGGGIGVPPLLEVAKELHERGVKVVTVLGFANKDAVILK
                     TELAQYGQVFVTTDDGSYGIKGNVSVVINDLDSQFDAVYSCGAPGMMKYINQTFDDHP
                     RAYLSLESRMACGMGACYACVLKVPESETVSQRVCEDGPVFRTGTVVL"
     gene            16739..17677
                     /locus_tag="ACL3EZ_001196"
     CDS             16739..17677
                     /locus_tag="ACL3EZ_001196"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004152 - dihydroorotate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HGR0392770.1"
                     /translation="MTTNRLQVSLPGLDLKNPIIPASGCFGFGQEYAKYYDLDLLGSI
                     MIKATTLEPRFGNPTPRVAETPAGMLNAIGLQNPGLEVVLAEKLPWLEREYPNLPIIA
                     NVAGFSKQEYAAVSHGISKATNVKAIELNISCPNVDHCNHGLLIGQDPDLAYDVVKAA
                     VEASEVPVYVKLTPSVTDIVTVAKAAEDAGASGLTMINTLVGMRFDLKTRKPILANGT
                     GGMSGPAVFPVALKLIRQVAQTTDLPIIGMGGVDSAEAALEMYLAGASAIGVGTANFT
                     NPYACPDIIENLPKVMDKYGISSLEELRQEVKESLR"
     gene            17719..19752
                     /locus_tag="ACL3EZ_001197"
     CDS             17719..19752
                     /locus_tag="ACL3EZ_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HGR0392771.1"
                     /translation="MNLGEFWYNKINKNRGRRLMKKVRFIFLALLFFLASPEGAMASD
                     GTWQGKQYLKEDGSQAANEWVFDTHYQSWFYIKADANYAENEWLKQGDDYFYLKSGGY
                     MAKSEWVEDKGAFYYLDQDGKMKRNAWVGTSYVGATGAKVIEDWVYDSQYDAWFYIKA
                     DGQHAEKEWLQIKGKDYYFKSGGYLLTSQWINQAYVNASGAKVQQGWLFDKQYQSWFY
                     IKENGNYADKEWIFENGHYYYLKSGGYMAANEWIWDKESWFYLKFDGKMAEKEWVYDS
                     HSQAWYYFKSGGYMTANEWIWDKESWFYLKSDGKIAEKEWVYDSHSQAWYYFKSGGYM
                     TANEWIWDKESWFYLKSDGKMAEKEWVYDSHSQAWYYFKSGGYMAKNETVDGYQLGSD
                     GKWLGGKATNKNAAYYQVVPVTANVYDSDGEKLSYISQGSVVWLDKDRKSDDKRLAIT
                     ISGLSGYMKTEDLQALDASKDFIPYYESDGHRFYHYVAQNASIPVASHLSDMEVGKKY
                     YSADGLHFDGFKLENPFLFKDLTEATNYSAEELDKVFSLLNINNSLLENKGATFKEAE
                     EHYHINALYLLAHSALESNWGRSKIAKDKNNFFGITAYDTTPYLSAKTFDDVDKGILG
                     ATKWIKENYIDRGRTFLGNKASGMNVEYASDPYWGEKIASVMMKINEKLGGKD"
     gene            complement(19813..21468)
                     /gene="pavA"
                     /locus_tag="ACL3EZ_001198"
     CDS             complement(19813..21468)
                     /gene="pavA"
                     /locus_tag="ACL3EZ_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_094859469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rqc2 family fibronectin-binding protein PavA"
                     /protein_id="HGR0392772.1"
                     /translation="MSFDGFFLHHIVEELRSELVNGRIQKINQPFEQELVLQIRSNRQ
                     SHRLLLSAHPVFGRIQLTQTTFENPAQPSTFIMVLRKYLQGALIESIEQVENDRIVEI
                     TVSNKNEIGDHIQATLIIEIMGKHSNILLVDKSSHKILEVIKHVGFSQNSYRTLLPGS
                     TYIAPPSTESLNPFTIKDEKLFEILQTQELTAKNLQSLFQGLGRDTANELERILVSEK
                     LSAFRNFFNQETKPCLTETSFSPVPFANQVGEPFANLSDLLDTYYKDKAERDRVKQQA
                     SELIRRVENELQKNRHKLKKQEKELLATDNAEEFRQKGELLTTFLHQVPNDQDQVILD
                     NYYTNQPIMIALDKALTPNQNAQRYFKRYQKLKEAVKYLTDLIEETKATILYLESVET
                     VLNQAGLEEIAEIREELIQTGFIRRRQREKIQKRKKLEQYLASDGKTIIYVGRNNLQN
                     EELTFKMARKEELWFHAKDIPGSHVVISGNLDPSDAVKTDAAELAAYFSQGRLSNLVQ
                     VDMIEVKKLNKPTGGKPGFVTYTGQKTLRVTPDSKKIASMKKS"
     gene            21573..22070
                     /gene="ybeY"
                     /locus_tag="ACL3EZ_001199"
     CDS             21573..22070
                     /gene="ybeY"
                     /locus_tag="ACL3EZ_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HGR0392773.1"
                     /translation="MYIEMVDETGQVSKEMLQQTQEILEFAAQKLGKEDKEMAVTFVT
                     NERSHELNLEYRDTDRPTDVISLEYKPELEIAFDEEDLLENPELAEMMSEFDAYIGEL
                     FISIDKAHEQAEEYGHSFEREMGFLAVHGFLHINGYDHYTPEEEAEMFGLQEEILTAY
                     GLTRQ"
     gene            22051..22446
                     /locus_tag="ACL3EZ_001200"
     CDS             22051..22446
                     /locus_tag="ACL3EZ_001200"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000378166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016301 - kinase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HGR0392774.1"
                     /translation="MDSQDNKRKWKNRDLISSLEFAITGIFTAIKEERNMRKHAVTAL
                     VVILAGFVFQVSRIEWLFLLLSIFLVVAFEIINSAIENVVDLASHYHFSMLAKNAKDM
                     AAGAVLVVSLFAALTGALIFLPRIWDLLF"
     gene            22463..23362
                     /gene="era"
                     /locus_tag="ACL3EZ_001201"
     CDS             22463..23362
                     /gene="era"
                     /locus_tag="ACL3EZ_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HGR0392775.1"
                     /translation="MTFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKI
                     MGIYTTDKEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVDTVLFMVPADEARGKGD
                     DMIIERLKAAKVPVILVVNKIDKVHPDQLLSQIDDFRNQMDFKEIVPISALQGNNVSR
                     LVDILSENLDEGFQYFPSDQITDHPERFLVSEMVREKVLHLTREEIPHSVAVVVDSMK
                     RDEETDKVHIRATIMVERDSQKGIIIGKGGAMLKKIGSMARRDIELMLGDKVFLETWV
                     KVKKNWRDKKLDLADFGYNEREY"
     gene            23411..24235
                     /gene="mutM"
                     /locus_tag="ACL3EZ_001202"
     CDS             23411..24235
                     /gene="mutM"
                     /locus_tag="ACL3EZ_001202"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001114577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008534 - oxidized purine nucleobase
                     lesion DNA N-glycosylase activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HGR0392776.1"
                     /translation="MPELPEVETVCRGLEKLIIGKKISSIEIRYPKMIKTDLEEFQRE
                     LPSQIIESMGRRGKYLLFYLTDKVLISHLRMEGKYFYYPDQGPERKHAHVFFHFEDGG
                     TLVYEDVRKFGTMELLVPDLLDAYFISKKLGPEPSEQDFDLQVFQSALAKSKKPIKSH
                     LLDQTLVAGLGNIYVDEVLWRAQVHPARSSQTLTAEEATAIHDQTIAVLSQAVEKGGS
                     TIRTYTNAFGEDGSMQDFHQVYDKTGQECVRCGTIIEKIQLGGRGTHFCPNCQRRD"
     gene            24235..24840
                     /gene="coaE"
                     /locus_tag="ACL3EZ_001203"
     CDS             24235..24840
                     /gene="coaE"
                     /locus_tag="ACL3EZ_001203"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259526.1"
                     /note="Dephospho-CoA kinase (CoaE) performs the final step
                     in coenzyme A biosynthesis; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004140 - dephospho-CoA kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HGR0392777.1"
                     /translation="MRKIIGITGGIASGKSTVTNFLRQQGFQVVDADAVVHQLQKPGG
                     RLFEALVQHFEQEIILENGELNRPLLASLIFSNPEEQKWSKQIQGEIIREELATLREQ
                     LAQTEEIFFMDIPLLFEQDYSDWFAETWLVYVDRDAQVERLMKRDQLSKDEAESRLAA
                     QWPLEKKKDLASQVLDNNGNQNQLLNQVHILLEGGRQDDRD"
     gene            24827..26026
                     /locus_tag="ACL3EZ_001204"
     CDS             24827..26026
                     /locus_tag="ACL3EZ_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter PmrA"
                     /protein_id="HGR0392778.1"
                     /translation="MTEINWKDNLRIAWFGNFLTGASISLVVPFMPIFVENLGVGSQQ
                     VAFYAGLAISVSAISAALFSPIWGILADKYGRKPMMIRAGLAMTITMGGLAFVPNIYW
                     LIFLRLLNGVFAGFVPNATALIASQVPKEKSGSALGTLSTGVVAGTLTGPFIGGFIAE
                     LFGIRTVFLLVGSFLFLAAILTICFIKEDFQPVAKEKAIPTKELFTSVKYPYLLLNLF
                     LTSFVIQFSAQSIGPILALYVRDLGQTENLLFVSGLIVSSMGFSSMMSAGVMGKLGDK
                     VGNHRLLVVAQFYSVIIYLLCANASSPLQLGLYRFLFGLGTGALIPGVNALLSKMTPK
                     AGISRVFAFNQVFFYLGGVVGPMAGSAVAGQFGYHAVFYATSLCVAFSCLFNLIQFRT
                     LLKVKEI"
     gene            26026..26175
                     /gene="rpmG"
                     /locus_tag="ACL3EZ_001205"
     CDS             26026..26175
                     /gene="rpmG"
                     /locus_tag="ACL3EZ_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HGR0392779.1"
                     /translation="MRVKINLKCSSCGSINYLTSKNSKTHPDKIEVLKYCPKEKKVTL
                     HLESK"
     gene            26215..26448
                     /gene="secG"
                     /locus_tag="ACL3EZ_001206"
     CDS             26215..26448
                     /gene="secG"
                     /locus_tag="ACL3EZ_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015136 - sialic acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015739 - sialic acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HGR0392780.1"
                     /translation="MYNLLLTILLVLSVVIVIAIFMQPTKNQSSNVFDASSGDLFERS
                     KARGFEAVMQRLTGILVFFWLAIALALTVLSSR"
     gene            26550..28904
                     /gene="rnr"
                     /locus_tag="ACL3EZ_001207"
     CDS             26550..28904
                     /gene="rnr"
                     /locus_tag="ACL3EZ_001207"
                     /EC_number="3.1.13.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HGR0392781.1"
                     /translation="MKDRIKEYLQDKGKVTVNDLAQALGKDSSKDFRELIKTLSLMER
                     KHQIRFEEDGSLTLEIKKKHEITLKGIFHAHKNGFGFVSLEGEEDDLFVGKNDVNYAI
                     DGDTVEVVIKKVADRNKGTAAEAKIIDILEHSLTTVVGQIVLDQEKPKYAGYIRSKNQ
                     KISQPIYVKKPALKLEGTEVLKVFIDKYPSKKHDFFVASVLDVVGHSTDVGIDVLEVL
                     ESMDIVSEFPEAVVKEAESVPDAPSQKDMEGRLDLRDEITFTIDGADAKDLDDAVHIK
                     ALKNGNLELGVHIADVSYYVTEGSALDKEALNRATSVYVTDRVVPMLPERLSNGICSL
                     NPQVDRLTQSAIMEIDKHGRVVNYTITQTVIKTSFRMTYSDVNDILAGDEEKRKEYHK
                     IVPSIELMAKLHETLENMRVKRGALNFDTNEAKILVDKQGKPVDIVLRQRGIAERMIE
                     SFMLMANETVAEHFSKLDLPFIYRIHEEPKAEKVQKFIDYASSFGLRIYGTASEISQE
                     ALQDIMRAVEGEPYADVLSMMLLRSMQQARYSEHNHGHYGLAADYYTHFTSPIRRYPD
                     LLVHRMIRDYGRSKEIVEHFEQVIPEIATQSSNRERRAIEAEREVEAMKKAEYMEEYV
                     GEEYDAVVSSIVKFGLFVELPNTVEGLIHITNLPEFYHFNERDLTLRGEKSGITFRVG
                     QQIRIRVERADKMTGEIDFSFVPSEFDVIEKGLKQSSRSGIGRGSNRRSDKKEDKRKS
                     GRSNDKRKYSQKDKKKKGKKPFYKEVAKKGAKHGKGRGKGRRTK"
     gene            28867..29334
                     /gene="smpB"
                     /locus_tag="ACL3EZ_001208"
     CDS             28867..29334
                     /gene="smpB"
                     /locus_tag="ACL3EZ_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HGR0392782.1"
                     /translation="MAKGEGKVVAQNKKARHDYTIVDTLEAGMVLTGTEIKSVRAARI
                     NLKDGFAQVKNGEVWLSNVHIAPYEEGNIWNQEPERRRKLLLHKKQIQKLEQETKGTG
                     MTLVPLKVYIKDGYAKLLLGLAKGKHDYDKRESIKRREQNRDIARVMKAVNQR"
     gene            29350..30210
                     /gene="tehB"
                     /locus_tag="ACL3EZ_001209"
     CDS             29350..30210
                     /gene="tehB"
                     /locus_tag="ACL3EZ_001209"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0046690 - response to tellurium ion
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase TehB"
                     /protein_id="HGR0392783.1"
                     /translation="MEKLVAYKRMPLWNKQTMPEAVQQKHNTKVGTWGKITVLKGALK
                     FIELTEEGEVLAEHLFEAGADNPMAQPQAWHRVEAATDDVEWYLEFYCKPEDYFAKKY
                     NTNPVHSEVLEAMQTVKQGKALDLGCGQGRNSLFLAQQDFDVTAVDQNGLALEILQSI
                     VEQEDLDMPVGLYDINSASIEQEYDFIVSTVVLMFLQADRIPAIIQNMQEKTSVGGYN
                     LIVCAMDTEDYPCSVNFPFTFKEGELADYYKDWELVKYNENPGHLHRRDENGNRIQLR
                     FATLLAKKIK"
     gene            30283..31236
                     /gene="coiA"
                     /locus_tag="ACL3EZ_001210"
     CDS             30283..31236
                     /gene="coiA"
                     /locus_tag="ACL3EZ_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000495911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HGR0392784.1"
                     /translation="MFVARDARGELVNVLEDKLEKQAYTCPACGGQIHLRQGPSVRTH
                     FAHKSLKDCDFFFENESPEHLANKESLYHWLKKETKVQLEYPLSELKQIADVFVNGNL
                     ALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
                     YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTV
                     SEDKDICRYIRQQLYYQNLFWMKEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIE
                     QDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE"
     gene            31255..33057
                     /gene="pepF"
                     /locus_tag="ACL3EZ_001211"
     CDS             31255..33057
                     /gene="pepF"
                     /locus_tag="ACL3EZ_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HGR0392785.1"
                     /translation="MVLQRNEINEKDTWDLSTIYPTDQAWEEALKDLTEQLETVAQYE
                     GHLLDSADNLLEITEFSLEMERQIEKLYVYAHMKNDQDTREAKYQEYYAKAMTLYSQL
                     DQAFSFYEPEFMEISEKQYADFLEAQPKLQVYQHYFDKLLQGKDHVLSQREEELLAGA
                     GEIFGSASETFAILDNADIVFPYVLDDDGKEVQLSHGTYTRLMESKKREVRRGAYQAL
                     YATYEQFQHTYAKTLQTNVKVQNYRAKVRNYKSARHAALAANFVPESVYDNLVAAVRK
                     HLPLLHRYLELRSKILGISDLKMYDVYTPLSSVEYSFTYQEALKKAEDALAVLGEDYL
                     SRVKRAFSERWIDVYENQGKRSGAYSGGSYDTNAFMLLNWQDNLDNLFTLVHETGHSM
                     HSSYTRETQPYVYGDYSIFLAEIASTTNENILTEKLLEEVEDDATRFAILNNFLDGFR
                     GTVFRQTQFAEFEHAIHQADQNGEVLTSDFLNKLYADLNQEYYGLSKEDNPEIQYEWA
                     RIPHFYYNYYVYQYSTGFAAASALAEKIVHGSQEDRDRYIDYLKAGKSDYPLNVMRKA
                     GVDMEKEDYLNDAFAVFERRLNEFEALVEKLGLA"
     gene            33059..33772
                     /locus_tag="ACL3EZ_001212"
     CDS             33059..33772
                     /locus_tag="ACL3EZ_001212"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HGR0392786.1"
                     /translation="MVESYSKNANHNMRRPVVKEEIVDLMRQRQKQVTGFLKELEDFA
                     RKENIPIIPHETVAYFRFLMETMQPKNILEIGTAIGFSALLMAEHAPNAKITTIDRNP
                     EMIGFAKENFAQFDSRKQITLLEGDAVDVLSTLTESYDFVFMDSAKSKYIVFLPEILK
                     HLEVGGVVVLDDIFQGGDVAKDIMEVRRGQRTIYRGLQKLFDATLDNPELTATLVPLG
                     DGILMLRKNVADVQLSESE"
     gene            33839..34780
                     /gene="prsA"
                     /locus_tag="ACL3EZ_001213"
     CDS             33839..34780
                     /gene="prsA"
                     /locus_tag="ACL3EZ_001213"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HGR0392787.1"
                     /translation="MKKKLLAGAITLLSVATLAACSKGSEGADLISMKGDVITEHQFY
                     EQVKNNPSAQQVLLNMTIQKVFEKQYGSELDDKEVDDTIAEEKKQYGENYQRVLSQAG
                     MTLETRKAQIRTSKLVELAVKKVAEAELTDEAYKKAFDEYTPDVTAQIIRLNNEDKAK
                     EVLEKAKAEGADFAQLAKDNSTDEKTKENGGEITFDSASTEVPEQVKKAAFALDVDGV
                     SDVITATGTQAYSSQYYIVKLTKKTEKSSNIDDYKEKLKTVILTQKQNDSTFVQSIIG
                     KELQAANIKVKDQAFQNIFTQYIGGGDSSSSSSTSNE"
     gene            complement(34897..35238)
                     /locus_tag="ACL3EZ_001214"
                     /pseudo
     CDS             complement(34897..35238)
                     /locus_tag="ACL3EZ_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            35652..35747
                     /locus_tag="ACL3EZ_001215"
                     /pseudo
     CDS             35652..35747
                     /locus_tag="ACL3EZ_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(36001..36621)
                     /locus_tag="ACL3EZ_001216"
     CDS             complement(36001..36621)
                     /locus_tag="ACL3EZ_001216"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HGR0392788.1"
                     /translation="MKLYFVRHGRTLWNQEGRFQGASGDSPLLPESIETLKRLGQYLK
                     EIPFDQIYSSDLPRAVKSAEIIQSQLYTPCSLEIVPNLREWQLGKLEGLKIATLEAIY
                     PQQIQAFRSNLAQFDTRMFGAESLYSTTQRTIQFIKSLKDSPAERILIVGHGANLTAS
                     LRTLLGYKEPLLRKDGGLANASLTIIETHDFETFTLNTWNDTSYQS"
     gene            complement(36621..37103)
                     /locus_tag="ACL3EZ_001217"
     CDS             complement(36621..37103)
                     /locus_tag="ACL3EZ_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016829 - lyase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HGR0392789.1"
                     /translation="MAKKVKIKKTLVEQILSKAAIPHQGIQINALEGELPQGYERDQI
                     FKTLALLGDKTGPIIGIVPITQHLSEKKLAKISGNKKVSMIPQKDLEKTTGYIHGANN
                     PVGIRQKHNYPIFIDKIALDLDQMIVSAGEVGHSIIVAPQDLASFVKADFVDILEDIK
                     "
     gene            complement(37103..37945)
                     /locus_tag="ACL3EZ_001218"
     CDS             complement(37103..37945)
                     /locus_tag="ACL3EZ_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HGR0392790.1"
                     /translation="MLSWLARVIKGIVIALGFILPGISGGALAAILGIYERMIGFLAH
                     PFKDFKENVLYFIPVAIGMLLGIGLFSYPIEYLLENYQVFVLWSFAGAIIGTVPSLLK
                     ESTRESDRDKIDLTWLWTTFIISGLGLYALNFVVGTLSASFLNFVLAGALLALGVLVP
                     GLSPSNLLLILGLYAPMLTGFKTFDLLGTFFPIGIGAGATLIVFSKLMDYALNNYHSR
                     VYHFIIGIVLSSTLLILIPNAGNAESIQYTGLSLVGYVIIAFFFALGIWLGIWMSQLE
                     DKYK"
     gene            complement(38040..38840)
                     /locus_tag="ACL3EZ_001219"
     CDS             complement(38040..38840)
                     /locus_tag="ACL3EZ_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HGR0392791.1"
                     /translation="MRKQIHPLILFSFLGIMMFILIINRPLNDNQSFKTKSNIAQIEA
                     QALKHLDKPIIDLSGWQRPEEINYDALSQNISGAIVRVHSGAQTTKENDASFINGIDK
                     AYKSHITELQKRNVPVAVYAYVAGKSVQEMEKAAEVFYNAASPYSPSYYWLDVEDKTM
                     SNMNEGVENFRAKLASLGAKNIGIYVGVYFMEEHSIDTGKFTSVWIPSYGSDSGFLES
                     SPKTDLDYDIHQYTSKGKIAGFDHDLDINVISPLKNKEETFRKLFLKP"
     gene            38984..40363
                     /gene="glmU"
                     /locus_tag="ACL3EZ_001220"
     CDS             38984..40363
                     /gene="glmU"
                     /locus_tag="ACL3EZ_001220"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002899862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0003977 - UDP-N-acetylglucosamine
                     diphosphorylase activity [Evidence IEA];
                     GO_function: GO:0019134 - glucosamine-1-phosphate
                     N-acetyltransferase activity [Evidence IEA];
                     GO_process: GO:0006048 - UDP-N-acetylglucosamine
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HGR0392792.1"
                     /translation="MSNFAIILAAGKGTRMKSDLPKVLHKVAGISMLEHVFRSVGAIQ
                     PEKTVTVVGHKAELVEEVLAGQTEFVTQSEQLGTGHAVMMTEPILEGLSGHTLVIAGD
                     TPLITGESLKNLIDFHINHKNVATILTAETDNPFGYGRIVRNDNAEVLRIVEQKDATD
                     FEKQIKEINTGTYVFDNERLFEALKNINTNNAQGEYYITDVIGIFRETGEKVGAYTLK
                     DFDESLGVNDRVALATAESVMRRRINHKHMVNGVSFVNPEATYIDIDVEIAPEVQIEA
                     NVTLKGQTKIGAETVLTNGTYVVDSTIGAGAVITNSMIEESSVADGVTVGPYAHIRPN
                     SSLGAQVHIGNFVEVKGSSIGENTKAGHLTYIGNCEVGSNVNFGAGTITVNYDGKNKY
                     KTVIGDNVFVGSNSTIIAPVELGDNSLVGAGSTITKDVPADAIAIGRGRQINKDEYAT
                     RLPHHPKNQ"
     gene            40373..40918
                     /locus_tag="ACL3EZ_001221"
     CDS             40373..40918
                     /locus_tag="ACL3EZ_001221"
                     /EC_number="3.6.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HGR0392793.1"
                     /translation="MEFEEKTLSRKEIYQGPIFKLVQDQVELPEGKGTAQRDLIFHNG
                     AVCVLAVTDEQKLILVKQYRKAIEAVSYEIPAGKLEVGENTAPVAAALRELEEETAYT
                     GKLELLYDFYLAIGFCNEKLKLYLASDLTKVENPRPQDEDETLEVLEVSLEEAKELIQ
                     SGHICDAKTIMAVQYWELQKK"
     gene            40930..41244
                     /gene="macP"
                     /locus_tag="ACL3EZ_001222"
     CDS             40930..41244
                     /gene="macP"
                     /locus_tag="ACL3EZ_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall synthase accessory phosphoprotein
                     MacP"
                     /protein_id="HGR0392794.1"
                     /translation="MGKSLLTDEMIERANRGEKISGPPLLDDNEETKILPTSSSRFGY
                     ANPKNHGFSQETLKIQVEPSIHKSRRIENTKRNVFNSKLNKILFAVIFLLILLVLAMK
                     LL"
     gene            41261..41953
                     /locus_tag="ACL3EZ_001223"
     CDS             41261..41953
                     /locus_tag="ACL3EZ_001223"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008782 - adenosylhomocysteine
                     nucleosidase activity [Evidence IEA];
                     GO_function: GO:0008930 - methylthioadenosine nucleosidase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009164 - nucleoside catabolic process
                     [Evidence IEA];
                     GO_process: GO:0019509 - L-methionine salvage from
                     methylthioadenosine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HGR0392795.1"
                     /translation="MKIGIIAAMPEELAYLVQHLYNVQEQVVLGNTYHTGTIASHEVV
                     LVESGIGKVMSAMSVAILADHFQVDALINTGSAGAVAEGIAVGDVVIADKLAYHDVDV
                     TAFGYAYGQMAQQPLYFESDKTFVAQIQESLSQLDQNWHLGLIATGDSFVAGNDKIEA
                     IKSHFPEVLAVEMEGAAIAQAAHTLNLPVLVIRAMSDNANHEANIFFDEFIIEAGRRS
                     AQVLLAFLKALD"
     gene            42030..42521
                     /gene="rocS"
                     /locus_tag="ACL3EZ_001224"
     CDS             42030..42521
                     /gene="rocS"
                     /locus_tag="ACL3EZ_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein RocS"
                     /protein_id="HGR0392796.1"
                     /translation="MSIEMTVSEIAEVLGLSRQAINNRVKELPEEDTDKNDKGVTVVT
                     RSGLIKLEEIYKKTIFEDEPVSEDVKQRELMEILVDEKNAEILRLYEQLKAKDRQLSE
                     KDEQMRIKDRQIAEKDKQLDQQQQLTLQAMKDQENLKLELDQAKEEVQSTKKGFFARL
                     FGG"
     gene            42619..43209
                     /locus_tag="ACL3EZ_001225"
     CDS             42619..43209
                     /locus_tag="ACL3EZ_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HGR0392797.1"
                     /translation="MERLEDYIAFDLEFNQHEGQTHLIQVSAVRFRDGREIDAYDSYV
                     HTSVPLKSFINGLTGITAETLKDAPPVEKVLEEFQEFVGSLLMIGYNAAKSDLPILAE
                     HGLDYSQQYKVDLYDEAFERRSSDLHGIANLKLQTVASFLGFQGQSHNSLEDARMTAR
                     VYESFLESDQARELLETESSLSNNPFGGLDLSQLFD"
     gene            43218..44981
                     /locus_tag="ACL3EZ_001226"
     CDS             43218..44981
                     /locus_tag="ACL3EZ_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphoryl diester phosphodiesterase
                     membrane domain-containing protein"
                     /protein_id="HGR0392798.1"
                     /translation="MKPEKPKKLGLKQIYLNLDKILFLFFLIFMIVEYLWVPFNSWLA
                     SFLLDQTGYLFISYNNVLAILTHSPLISLAFLALIVINFLVAYFQIGLLFIGARHLLY
                     NEKRRLIEYIRKVFHESFEFMKKLTGAKALFIFFYIAMLFPFIRKMLKIYYLNKIVIP
                     EFIQAYLEDKYWMWWLSILLLSLIFLYVSVRLMFALPKIVYDQLTVREAVMFSLEKTK
                     KRVTFYAWNLFYILLKAHLLFYLPLIPLLLAQTLVDDITQRESLILGILNFVVIKNLY
                     YMALTYFLVKFVSFLTGKELDMLPRREKDHIVRWGVMTCASFFFALEGYIYLEAPMVH
                     LPQLISHRGVSNANGIQNTVESLETTAQLKPDLVETDVQETKDGQFVMMHDANLKNLA
                     GINKSPQDLNLEELKGIDIFENGYQTKISSFEDYLSRANELGQKLLIEIKTSKKDSPD
                     MMNRFLARYAAKLKIYGHQIQSLDYHVVEKVRQYDAELPVYFIMPYNSVFPKTRATGY
                     TMEYSTLDEYFVSKLWTTDQKLYVWTVNDSEAISKSLHLGVDGVITDDLEKVQREIEV
                     AQEDPEYTDLLLKKALEFFEF"
BASE COUNT        13662 a         8249 c        10049 g        13182 t
ORIGIN      
        1 tggaaagtaa gaaatattga agctgaggcg attagaagaa attgtgagcg tggtgctatt
       61 ttttcaggta aaataaaaca tcacgaagat tctcagttta aaggagacca ctatgttgaa
      121 tgttatgctg ttttagataa tacggttata gcaagagata gaataacagt ccctatcgat
      181 ccgttatgtg gaaaagattt tatagagtag catataattg attcttaact ggaatactct
      241 ctatctcttt acatcaagaa aatgactaaa cagggaagtt tgccttcttc cctttttttg
      301 ttatactagt agaagaaaaa aatagaaaga tttgtgggag tgaaaaagtc cgggggactt
      361 tttcagcttg agccaagaaa ttcgagagcg aggaaagtct gggggacttt ttcagcttga
      421 gccaagaaat tcgagagcga ggaaagtctg ggggactttt tcagcctgag ccaagaaact
      481 cgaaatctcg taagtctgat tggctttttc aatgtgaatc ttaacttcac actcccaaag
      541 aggtattagt gtcgtgtctc aatcttatat caatgttatc ggtgctggtt tggcaggttc
      601 tgaagcagct taccaaatcg cagagcgtgg tattccagtt aaactttatg aaatgcgtgg
      661 tgtcaagtct acaccccagc ataaaacaga caattttgct gagttggttt gttccaattc
      721 tttgcgtggg gatgctttga caaatgcagt tggtcttctc aaggaagaaa tgcgtcgctt
      781 gggttctgtt atcttggaat ctgctgaggc tacacgtgtt cctgccggtg gagcccttgc
      841 ggtggatcgt gatggtttct ctcaaatggt gaccgaaaaa gtggtcaacc accccttgat
      901 tgaagtggtg cgtgatgaaa ttacagaatt gccaacagat gttattacag ttgtggcgac
      961 tggtcccttg actagcgatg ccctggctga aaagattcat gcccttaata atggcgatgg
     1021 cttctatttc tacgatgcag cagcgcctat tatcgatgtc aacactatcg atatgagtaa
     1081 ggtctatctc aaatctcgtt atgataaggg agaagcagcc tatctcaatg ctccaatgac
     1141 caagcaagag tttatggatt tccatgaagc cttggtcaat gcggaagaag caccgctcaa
     1201 ttcttttgaa aaagaaaagt actttgaagg atgtatgcca atcgaagtta tggccaaacg
     1261 tggcattaaa actatgcttt atggccctat gaagccagtc ggtcttgagt atccggacga
     1321 ctacacagga cctcgtgatg gagaatttaa aacaccttat gcggttgtgc aacttcgtca
     1381 ggataatgca gctggtagcc tatacaatat tgttggtttc cagacccacc tcaaatgggg
     1441 agaacaaaag cgtgtcttcc aaatgattcc gggtcttgaa aatgcggagt ttgtccgtta
     1501 tggtgtcatg catcgcaatt cttacatgga ttcaccaaat cttcttgagc agacttaccg
     1561 ttccaagaaa caaccaaatc tcttctttgc tggtcagatg acgggggtgg aaggctatgt
     1621 tgagtcggcg gcttcgggct tagttgcggg aattaacgca gctcgtctct tcaaggaaga
     1681 aagcgaggtt attttccccg agacgacagc gattggaagc ttagctcatt acattaccca
     1741 tgccgacagc aaacatttcc aaccaatgaa tgtcaatttt gggatcatca aggagttgga
     1801 aggcgagcgt atccgtgata agaaggctcg ttatgaaaaa attgcagagc gtgcccttgc
     1861 cgacttagag gaatttttga ctgtctaatt tttttgaaag aattgttcat gatactataa
     1921 aaatcttaga aattgtgata aaataggtag gatgaaagaa ggagagtgaa aatggcgaat
     1981 cccaagtata aacgtatttt aatcaagtta tcaggtgaag cccttgccgg tgaacgtggc
     2041 gtagggattg atatccaaac agttcaaaca atcgcaaaag agattcaaga agttcatagc
     2101 ttaggtatcg aaattgccct tgttattggt ggaggaaatc tctggcgtgg agaacctgca
     2161 gcagaagcag gtatggaccg tgttcaggca gattacactg gaatgcttgg gactgttatg
     2221 aatgctcttg tgatggcaga ttcattgcaa caagttgggg ttgatacgcg tgtacaaaca
     2281 gctattgcta tgcaacaagt ggcagagcct tatgtccgtg gacgtgccct tcgtcacctt
     2341 gaaaaaggcc gtatcgttat ctttggtgct ggaattggtt caccatactt ctcgacagat
     2401 acaacagcgg cccttcgtgc agctgaaatc gaagcagatg ccatcctcat ggctaaaaat
     2461 ggcgtcgatg gtgtgtacaa tgccgatcct aagaaggaca agacagccgt taagtttgaa
     2521 gaattgaccc accgtgatgt tatcaacaaa ggtcttcgta tcatggactc aacagcctca
     2581 accctctcaa tggacaacga cattgacttg gttgtcttca acatgaacca atcaggcaac
     2641 atcaaacgtg ttgtatttgg tgaaaatatc ggaacaacag tttcaaataa tatcgaagaa
     2701 aaggaataag aaagaatatg gctaacgtaa ttattgaaaa agctaaagag agaatgaccc
     2761 agtctcacca atcacttgct cgtgaatttg gtggtatccg tgctggtcgt gccaatgcaa
     2821 gcttgcttga ccgtgtacat gtagaatact atggagtcga aactcctctt aaccaaatcg
     2881 cttcaattac gattccagaa gcgcgtgttt tgttggtaac accatttgac aagtcttcat
     2941 tgaaagacat cgaacgtgcc ttgaacgctt ctgatcttgg tatcacaccg gctaatgacg
     3001 gttctgtgat tcgcttggtt atcccagctc ttacagaaga aactcgtcgt gaccttgcta
     3061 aagaagtgaa gaaggtcggc gaaaatgcta aagtggctgt ccgcaatatc cgtcgcgatg
     3121 ctatggacga agctaagaag caagaaaaag caaaagaaat cactgaagac gaattgaaga
     3181 ctcttgaaaa agatattcaa aaagtaacag acgatgctgt taaacacatc gacgacatga
     3241 ctgctaacaa agagaaagaa cttttggaag tctaaaaata aacagaaaaa ctcagttggc
     3301 attgctggct gagttttatt cgaaagaagg aaatatgaat acaaatcttg caagttttat
     3361 cgttggactg atcatcgatg aaaatgaccg tttttacttt gtgcaaaagg atggtcaaac
     3421 ctatgctctt gctaaggaag agggccaaca tacagtaggg gatacggtca aaggttttgc
     3481 atacacggat atgaagcaaa aactccgcct gacaacctta gaagtgactg ccactcagga
     3541 ccaatttggt tggggacgtg tcacagaggt tcgtaaggac ttgggtgtct ttgtggatac
     3601 aggccttcct gacaaggaaa tcgttgtgtc actcgatatt ctccctgtgc tcaaggaact
     3661 ctggcctaag aagggcgacc aactctacat ccgtcttgaa gtggataaga aagaccgtat
     3721 ctggggcctc ttggcttatc aagaagactt ccaacgtctc gctcgtcctg cctacaacaa
     3781 catgcagaac caaaactggc cagccattgt ttaccgtctc aagctgtcag gaacttttgt
     3841 ttacctacca gaaaataata tgcttggttt tattcatcct agcgagcgtt acgcagagcc
     3901 acgtttgggg caagtattag atgcgcgcgt tattggtttc cgtgaagtgg accgcactct
     3961 gaacctctcc ctcaaaccac gctcctttga aatgttggaa aacgatgctc agatgatttt
     4021 gacttatttg gaaagtaatg gcggtttcat gaccttaaat gataagtcat ctccagacga
     4081 catcaaggca acctttggca tttctaaagg tcagttcaag aaagctttag gtggtcttat
     4141 gaaggctggt aaaatcaagc aggaccagtt tgggacagag ttgatttagg gaggcttatg
     4201 agaaaatcat tttacacttg gctcatgacc gagcgcaatc ctaaaagtaa cagtcccaaa
     4261 gcaattttgg cagacctcgc ttttgaagag gcagcttttc caaaacatac agatgatttt
     4321 gatgaggtca gtcgcttttt ggaggagcat gccagtttct cttttaacct aggagatttt
     4381 gacagcattt ggcaggaata tctagaacac tagcatttat tcattgggtt tgggctagta
     4441 atttctccat ccctctgcta taataaaaag aaataaaagg attagagagg ttctttattt
     4501 gaaggaacat tcaatagaca ttcaactgag tcatccagat gacctgtttc atctttttgg
     4561 ttccaatgaa cgccatcttc gtttgatgga agaagagctt gatgttgtga ttcatgctcg
     4621 tacggagatt gtccaggttt tgggagaaga gtctgcctgt gaggaagccc gtcaagttat
     4681 tcaggctttg atggtcttgg taaatcgtgg gatgaccgtt ggtacgccag atgtagtcac
     4741 tgcgattagc atggtcaaaa atgatgaaat tgacaagttt gtcgcccttt acgaagaaga
     4801 aattatcaaa gataatactg ggaaacctat ccgtgtcaaa accctagggc aaaagcttta
     4861 tgtggacagt gtcaaacagc atgatgtgac ctttggaatt gggccagcag gtacagggaa
     4921 gaccttcctt gcagtgacct tggcagtgac tgcccttaaa cgtgggcaag tcaagcgaat
     4981 tatcctaact cgtccagcgg tggaagcggg agagagtctt ggatttcttc cgggtgatct
     5041 taaggagaag gtggatcctt accttcgtcc tgtttacgat gccttgtatc agattctggg
     5101 gaaagaccaa acaactcgac tcatggagcg tgaaattatc gagattgcgc cccttgccta
     5161 tatgcgtgga cggaccttgg atgatgcctt tgtcattctc gatgaggcgc aaaatacgac
     5221 catcatgcag atgaagatgt tcttgactcg tttaggtttt cattctaaga tgattgtcaa
     5281 tggagatatt agtcagattg acctgccacg taatgtcaag tccggtttga ttgatgctca
     5341 agagaaactc aagaacatcc atcagattga ctttgttcat ttttcagcca aggatgtggt
     5401 tcgccatcca gttgtcgctc agattatccg agcctatgaa tattctactg aagttgcaca
     5461 cgactgattt tgaggaagtt tgcctgcaaa agaatatact tttgagagag gaaaatccag
     5521 ttgtataggc taaaggtttt atccaaaggt ttgagacaac gattaggcac gatggaaaga
     5581 acttttatgt ggctgatgac gatcagtgca tcttcctgtg tcataatcac agggcacaag
     5641 aaagtaggaa tttgaaaaga tgattgacca actatctaag tattacagtt gtaggatact
     5701 aactgaaaag gatattccaa gtattttatc tttatatgaa agtaatcctc tgtattttca
     5761 gcattgtcca ccagagccaa attttgcaac tgtaaaagag gacatgcttt gtctacctga
     5821 aggtaaagct aaggctgata agttttttgt tggattttgg aatggatctg accttgtggc
     5881 tgttatagat tttgtctatg cacatcctga tgaggagact gtttttattg gtttgtttat
     5941 ggttgatcaa gcctatcaga ggaaagggat tggtagtcat attgtgacag aagcactagc
     6001 ttattttgct aagaactttc gaaaggcacg tttggcttat gttaagggaa atccgcaatc
     6061 tcagcatttt tgggaaaagc agggctttaa atcaattgga tgcgaggtta agcaagaact
     6121 ctatacggtt gttatcgctg aacagagcct agaagattag aaatggcatc aagtaagaac
     6181 tatttggaat ttgttttgga acaattatca ggattagatg atgtgactta ccgttccatg
     6241 attggggagt atattcttta cttccgcggc aagattattg gcggcattta tgacgatcgc
     6301 tttttagtta aacccgtgca agcagtctta gataagattg accaatcttc ttttgagttt
     6361 ccatacaaag gtgccaaaga aatgatttga gtggaagaac ttgataataa gatgtttcta
     6421 taagacctga ttttagctat gtataaccaa ctgccaacgc ccaaacctaa aaagaaaaag
     6481 caagggtgaa cgaagtaaaa aagaagtctg ctaaggccct gtctttgcac gggtaaaatt
     6541 ttatatataa aaagaagctg ggactaaaga gctcagcttc ctttggttta tataattgtc
     6601 attacaagac gaagtggttg ggcgaaactc tgttgacttt attcaattta gagtttctta
     6661 tgcacaattg agtctggaac gaaagtctcc agttgcaaag tatacagtac aataaaccaa
     6721 cgatgtaata gctgatgaca caaagcacag tgggtaggac ttgcgaagtc acccttttct
     6781 tttcaaaatt tatactaaat cattgatatc agtgtagtca cgattaagtc cttgagcaac
     6841 tggtaggcta gtcaagtaac cttgataagt ggtcacacct tgacgcaagc cttcatcttc
     6901 agagattgct tgtgcgaatc ctttgccagc caaagcttcg atataaggaa gagtgacatt
     6961 ggttagggcg atggttgaag tgcgggcaac cgcaccaggg atattggcaa cggcatagtg
     7021 gagaacaccg tgtttttcat agacgggttc atcgtgcgtt gtcacacggt cagctgtttc
     7081 gataacgcca ccttggtcaa cagcaacgtc aacgatacag agcctggacg catttgtttg
     7141 accatctcat ctgtcatcaa ttccggtgct tttgcaccag ggatgagaat ggctccaatc
     7201 accacatcag catctctcat acttgcttca atgttgaatg aattagatat aagagtttga
     7261 atttgacttc caaagacttc ttctagaact gagagacgct tggcactaat atctaaaata
     7321 gtcacttgag caccaagacc aagggcgatg cgggcagcat gtgtaccgac gacaccatca
     7381 ccgatgatag ttacttttcc ttttggaaca cctggtacac caccaggtag aacaccagag
     7441 ccaccagctt gcttagtaag gaagtgagct ccgatttaaa cagccatacg acctgcaacc
     7501 tcactcatag gaacgaggag cggtagttgt ccttgattgt cacgaacagt ttcataggca
     7561 attcctgttg tttttgctgc taacatagca tctgctaatt ctggagcagc ggccatgtgc
     7621 aagtaggtga agagaagaag atcgtcgcgc aagtaaccgt attcagaact taaaggttct
     7681 tttactttca caaccaactc tgctgcccaa gcttcaccag cagtagcgac aatctcagct
     7741 ccttgctttt gatagtcagc atcagtaaag ccagaaccga gaccagcatt tgtttcgata
     7801 aggacacgat gaccacgact aactaagcta tgaacacctg caggtgtgag ggcgacacgg
     7861 ttttcgttat ttttaatttc ttttgggatt ccgattaaca ttgagataac ctacctttca
     7921 attgacggtc ttgttttggt tgtcacattc cagttcataa atcaaaaatg tgacggtttc
     7981 attgtatatg aaaccgcttc aaaaatcaag aaaaacttgt catccaaatt tttttatgct
     8041 agactagtga aaatcaagct ctaatggagg gaaaagtatg gaatcaatat ttgtgaaatt
     8101 tgcccagtat ccgtctatag aaacggagcg tttattgctt agacctgtaa ctttggatga
     8161 tgcggaagca atgtttgact atgcctcgga caagggtaat acacgttaca cttttccaac
     8221 caatcaaagc ttggaagaaa ccaagaataa cattgctcag ttctacttgg ctaatccctt
     8281 gggacgttgg gggattgaat taaaagataa cggcaagttt atcggaacta ttgacttaca
     8341 caagattgat cctgttctta agaaggcagc tattggctac attatcaata aaaagtattg
     8401 gaatcaagga ttaacgccag aaaccaatcg tgctgtgatt gagctagctt ttgagaagat
     8461 aggaatgaat aagttagttg ctttatacga taaggacaat tctgcgtcag gaaaggtcat
     8521 ggagaaatca ggcatgcgtt tttcccatgc agaaccatat gcttgtatgg accagcatga
     8581 aaaaggccga atcgtgacaa gagttcatta tgtcttgacc aaggaagact attttgcaaa
     8641 taaataagca gttgaaaaga aatttttcga ctgttttttc ttcctcttac gaataatcta
     8701 agagaggaga aaatatggaa gcaattatcg agaaaatcaa agagtataaa atcatcgtca
     8761 tctgtactgg tctgggcttg cttgtaggcg gatttttcct gctaaagcca gctccacaaa
     8821 cacctgtaaa ggaaacgaat ttgcaggctg aagttgcagc tgtttccaag gatttggtat
     8881 ccgaaaagga agtgaacaag gaagagaagg aagaacccct tgaacaagat ctaatcacag
     8941 tagatgtcaa aggtgctgtc aaatcgccag ggatttatga cttgcctgta ggtagtcgag
     9001 tcaatgatgc tgttcagaag gctggtggct tgacagagca agcagacagc aagtcgctca
     9061 atctagctca gaaagttagt gatgaggctc tggtttacgt tcctactaag ggagaagaag
     9121 cagttagtca acagactggt tcggggacag cttcttcaat aagcaaggaa aagaaggtca
     9181 atctcaacaa ggccagtctg gaagaactca agcaggtcaa gggactggga ggaaaacgag
     9241 ctcaggacat tatcgaccat cgtgaggcaa atggcaagtt caagtcagta gacgagctca
     9301 agaaggtctc tggcattggt ggcaaaacaa tagaaaagct taaagactat gttacagtgg
     9361 attaagaatt tctctattcc cctaatttac ctgagttttc tattactttg gctttattac
     9421 gctattttct cagcatctta tcttgctttg ttgggctttg tttttctgct agtctgtctc
     9481 tttatccaat ttccgtggaa atctgctggt aaagttctaa taatttgcgg aatctttgga
     9541 ttttggtttg tttttcaaaa ttggcaacag agtcaagcga gtcaaaatct ggcggattct
     9601 gttgaaaggg tacggatttt gcctgatact attaaggtta atggtgatag tctatccttt
     9661 cgtggcaagt ctaacggtcg tgctttccaa gtctattata aactccagtc cgaggaggag
     9721 aaagaagcct ttcaagcttt aaccgacctg catgagatag gactagaagg gaagctttcg
     9781 gagccagaag ggcagagaaa ttttggtggc tttaattacc aagcctatct gaagactcag
     9841 ggaatttacc agactctcaa tatcaaaaaa atccagtcac ttcaaaagat tggcagttgg
     9901 gatataggag aaaacttgtc cagtttacgt cgaaaggctg tggtttggat taagacgcac
     9961 tttccagacc ctatgcgcaa ttacatgaca ggactcttgc tgggacatct ggacaccgac
    10021 tttgaggaga tgaatgagct ttattccagt ctaggaatta tccacctctt tgccctatct
    10081 ggtatgcagg taggtttttt catgaatgga tttaagaaac ttctcttgcg attgggcttg
    10141 acccaagaaa agttgaaatg gctgacttat cccttttccc ttatctatgc gggactaact
    10201 ggattttcag catcggttat tcgcagtctc ttgcaaaagc tactggctca acatggggtt
    10261 aagggcttgg ataattttgc cttgacggtg cttgtcctct ttattgtcat gccaaacttt
    10321 ttcttgacag caggaggagt cttgtcctgc gcttatgctt ttatcctgac catgaccagc
    10381 aaagaagggg aggggctcaa ggctgttact agtgaaagtc tagtcatctc cttgggcata
    10441 ttgcccattc tatccttcta ttttgcggaa tttcaacctt tgtctatcct tttgaccttt
    10501 gtcttttcct ttctatttga cttgaccttc ttaccgctct tgtctatttt atttgtcctt
    10561 tcctttctct atccagtcat tcagctgaac tttatctttg aatggttgga gggcattatt
    10621 cgcttggtgt cacaggtgac aagtagacct ctggtctttg gacaacccaa tgcatggttt
    10681 ttaatcctat tgttaatttc cttggctttg gtctatgatt tgagaaaaaa cattaaaaag
    10741 ctaacggtat tgtgcttatt gattacaggg ctctttctcc tgaccaagca tccactggaa
    10801 aatgaaatca ccatgctgga tgtggggcaa ggagaaagta ttttcctacg ggatgtaact
    10861 gggaaaacca ttctcataga tgtaggtggt aaggcagaat cttataagaa aatcgaaaaa
    10921 tggcaagaaa aaatgacgac cagcaatgcc cagcgaacct tgattcccta tctcaaaagt
    10981 cgaggagtag ctaagattga ccagctaatt ttgactaaca cggacaagga acatgtcgga
    11041 gatttgttag aggtgaccaa ggctttccat gtaggggaga ttttagtatc aaaaggcagt
    11101 ttgaagcaga agcaatttgt ggtagaacta caggcgactc aaacaaaggt gcgtagtatg
    11161 acagtagggg agaacttgcc catttttgga agtcagttag aagttctatc cccaaggaaa
    11221 atgggagatg gaggacacga tgatacccta gttctgtatg ggaaattctt ggataagcaa
    11281 tttctcttca cgggaaattt ggaggagaaa ggagagaagg acttgctgaa gcactatcca
    11341 gacttgaaag taaatgtttt gaaagctagc caacatggca ataaaaaatc atcaagtcca
    11401 gcctttctag aaaaactcaa accagagctt actcttatct cagttggaaa gagcaatcga
    11461 atgaaactcc cccatcagga aacattgaca cgactggaag gtatcaatag caaagtttac
    11521 cgaactgacc agcaaggagc tatacggttt aaaggttgga atagttggaa aatcgaaagt
    11581 gttcgatagg aaagataaat gttgtagatt agtgaaataa actaaaaatt tgttgcataa
    11641 taatgataaa aatggtataa tgaaaacgta ttcaatactg aggatataaa atcattaaaa
    11701 attagcaaaa atcgtttaat tagttagttt atgattattg gtctttttca gtccagtata
    11761 tctgctgtga cagtcactaa aagttacaag tatgattgga atacggtttg ggaatatagt
    11821 actaactatc acgaccatca gtatgcttgg attccgtcat ggtctcgtta ttacagctat
    11881 tctgagtatc cagttggttc tggctggaac tacgctcgtt atgaggtcat aaactactat
    11941 actggaggtt attaatcctt aaagagtgag aaaaggaggg ctggatatgt taaggcttac
    12001 tcatgttacc ctaaaaacgc gacaagtcat cttgcaagat gcggatttta cctttaaaaa
    12061 gggtagggtt tatggtcttc ttgctatcaa tggctcggga aagacgacac tattccgagc
    12121 tatgagcaag ttgcttcccc ttagtagtgg acacatcgca gttcctcctt ctttgtttta
    12181 ttatgagagc gttgaatggc tggatggaaa cttaagtggg atggactacc ttcgtctcat
    12241 aaaaaacatc tggaagtcag acctaaactt gagagatgaa atcgcctact gggaaatggc
    12301 tgactatatc agtcttccca tccgcaagta ttccttaggc atgaagcaac gcttggtgat
    12361 tgctatgtat tttctcagtc aggccaaatg ctggctcatg gatgagatta caaatggctt
    12421 agacgagtat tatcgacaga agttttttga taggctagca caaatcgata gacaagaaca
    12481 gctggttctt ttaagttccc actataagga agagttggtt gatatctgcg atagagtagt
    12541 aaccattcat caggggcaga tagaagaggt ttagtttatg aaagatgtta gtctattttt
    12601 attgaaaaaa gttttcaaaa gtcgtttaaa ctggattatc ttacttttat ttgcatctgt
    12661 actcggtgtt accttttatt taaatagtca gactgcaaac tcacacagct tggagagcag
    12721 gttggaaagt cgcattgcag ccaacgagag ggctatcaat gaaaatgaag agaaactctc
    12781 ccaaatgtct gataccagct cggaggaata ccagtttgct aaaaataatt tagacgtgca
    12841 aaaaaatctt ttgacgcgaa agacagaaat tctaacttta ctaaaagaag ggcgctggaa
    12901 agaagcctac tatctgcagt ggcaagatga agagaagaat tatgaatttg tatcaaatga
    12961 cccgactgct agctctggct taaaaatggg ggttgaccgc gaacggaaga tttaccaagc
    13021 cctgtatccc ttgaacataa aagcacatac tttggagttt ccgacccacg ggattgatca
    13081 gattgtctgg attttagagg ttatcatccc aagcttgttt gtggttgcga ttatttttat
    13141 gctaacacaa ctatttgcag aaagatatca aaatcatctg gacacagctc acttatatcc
    13201 tgtttcaaaa gtgacatttg caatatcctc tcttggagtt gtagtgggat atgtaactgt
    13261 gctgtttatc ggaatctgtg gcttttcttt tctagtggga agtctgataa gtggttttgg
    13321 acagttagat tatccctacc caatttatag cttagtgaat caagaagtaa ctattgggaa
    13381 aatacaagat gtattatttc ctggcttgct cttagctttc ttagccttta tcgtcattgt
    13441 ggaagtcgtc tacttgattg cttacttttt caagcaaaaa atgcctgtcc tctttctttc
    13501 actcattggg attgttggct tattgtttgg catccaaaca attcagcctc ttcaaaggat
    13561 tgcacatctg attcccttta cttacttgcg ttcagtggag attttatctg gaagattatc
    13621 taagcagatt gataatgtcg atctaaattg gagcatgggg atggtcttac ttccttgcct
    13681 gattatcctt ttgttagtgg ggattctatt tatcgaaagc tggggaagtt cacgtaaaaa
    13741 ggaagttttt aaagtttagt tttcctatag ggaagctaaa gaaaaactaa catagggaga
    13801 gaatcaactt ggttctctct ttttgattcg aaaaccaaac caaaatacaa acacaaactt
    13861 ttcaaaaaat aactttttat cttgacaaga gctagaaaac ttggtatcat ataaaagttg
    13921 agaaaagcag aagtgagagc ttctcgcctt gtgacattaa gttgcctggc cctacggatg
    13981 aaaagtttcg aagaaacgct atcataacgt gcgggcttgt atatttacaa gtccgctatt
    14041 gtttttctct aataaaacaa aagaggtgaa aaccatagca aagcaagact tattcatcaa
    14101 tgatgagatt cgtgtacgtg aagttcgctt gattggtctt gaaggagaac agctaggtat
    14161 caagccactc agtgaagcgc aagctttggc tgataacgct aatgttgacc tagtattgat
    14221 tcaaccccaa gccaaaccgc ctgttgcaaa aattatggac tacggtaagt tcaaatttga
    14281 gtaccagaag aagcaaaaag aacaacgtaa aaaacaaagc gttgttactg tgaaagaagt
    14341 tcgtctaagt ccaactattg acaagggtga ctttgataca aaacttcgta atgcacgtaa
    14401 gttccttgaa aaaggaaata aagttaaggt atctattcgc tttaagggtc gtatgattac
    14461 ccataaagag attggtgcaa aagttttagc cgagtttgct gaagcaactc aagatattgc
    14521 catcatcgaa caacgtgcta aaatggatgg acgtcaaatg ttcatgcaat tggcgccagc
    14581 gactgacaaa aaataattgt cagaaagtta aataaaggag aaaaaatcat gccaaaacaa
    14641 aaaacacacc gcgcatcagc taaacgtttc aaacgtacag gttctggtgg acttaaacgt
    14701 ttccgtgctt acacttctca ccgtttccac ggaaaaacta agaaacaacg tcgtcatctt
    14761 cgtaaagcat ctatggtgca ttcaggagat tacaaacgta tcaaagcaat gcttactcgc
    14821 ttgaaataat agcttgactg taagtaaaca attctaggaa atatttggag gaaataaaac
    14881 atggcacgtg ttaaaggtgg cgttgtatca cgcaaacgtc gtaaacgtat tcttaaatta
    14941 gcaaaaggtt actatggagc taaacacatc ttgttccgta ctgcaaaaga acaagtaatg
    15001 aactcttact actatgcata ccgtgaccgt cgtcagaaaa aacgtgactt ccgcaaattg
    15061 tggattactc gtatcaatgc ggcagctcgt atgaacggac tttcatactc acaattgatg
    15121 catggtttga aattggctga gattgaagtt aaccgtaaaa tgcttgctga cttggctgtt
    15181 aacgatgcag tagctttcac agctcttgca gatgcagcta aagcaaaact tggtaaataa
    15241 caactgatga gactggaaca ggattgtcca gtctttttaa aaataaagga gaaagatatg
    15301 gcttcaaaaa tgctacacac ttgcttacga gtagaaaatc ttgaaaaatc aatcgcattt
    15361 tatcaagatg cttttggttt taaagaattg cgtcgcagag attttccaga ccatgccttc
    15421 acgattgtct atctaggtct tgagggtgat gattatgagt tggagttgac ttataactac
    15481 gatcacggtc cgtatgtggt tggtgatggg tttgcccata tcgccctcag tacacctgat
    15541 cttgaggcac ttcatcaaga acacagtgca aaaggctatg aagtgactga gccaaatggt
    15601 ctaccaggaa ctacaccaaa ctattacttt gttaaagacc ctgatggata taaggtcgaa
    15661 gtcattcgtg aaaaataatt tcgtgcaagt taagtagaat attcgttttc tacttgactt
    15721 tttttagctg aaagagtata ctaataaaaa ttcaaccttt aaggggagtc cagagagact
    15781 cacaaggtgt cagataaaag aatagtgcaa ttttctagag gagacctttt gagtgtgctc
    15841 tcttgtgttg tacgatttta actgaggcct tgcactagca aggtcttttc tttatctggt
    15901 ccccttaaaa tttaaggagg aaaagttatg aatctcacat gtaagaagcg tttgggtgtc
    15961 attcggttgg aaaccatgaa ggtggttgca caagaggaaa tcgcgccagc aatctttgaa
    16021 ttagtcctag aaggagaaat ggttgaagcc atgcgagcag gccaatttct tcatctgcgt
    16081 gtaccagacg atgcccatct cttacgtcgt cctatttcaa tttcgtctat tgacaaggca
    16141 aacaagcagt gtcacctcat ttatcggatt gagggagctg ggactgcaat tttttcaacc
    16201 ttaagtcagg gagacactct tgatgtgatg gggcctcagg gaaatggttt tgacttgtct
    16261 gaccttgatg agcagaatca ggttctcctt gttggtggtg ggattggtgt tccacccttg
    16321 cttgaggtgg ccaaggaatt gcatgaacgt ggagtgaaag tagtgacagt cctcggtttt
    16381 gctaataagg atgctgttat tttgaaaacg gaattggctc agtatggtca ggtctttgta
    16441 acgacagatg atggttctta tggcatcaag ggaaatgttt ccgttgttat caatgattta
    16501 gatagtcagt ttgatgctgt ttactcgtgt ggggctccag gaatgatgaa gtatatcaat
    16561 caaacctttg atgatcaccc aagagcctat ttatctctgg aatctcgtat ggcttgtggg
    16621 atgggagctt gctatgcctg tgttctaaaa gtaccagaaa gcgagacggt cagccaacgc
    16681 gtctgtgaag atggtcctgt tttccgcaca ggaacagttg tattataagg agaaaattat
    16741 gactacaaat cgattacaag tgtctctacc tggtttggat ttgaaaaatc cgattattcc
    16801 agcatcaggc tgttttggct ttggacaaga gtatgccaag tactatgatt tagacctttt
    16861 aggttctatt atgatcaagg cgacaaccct tgaaccacgt tttgggaatc caactccaag
    16921 agtggcagag acgcctgctg gtatgctcaa tgcaattggc ttgcaaaatc ctggtttaga
    16981 ggttgttttg gctgaaaagc taccttggct ggaaagagaa tatccaaatc ttcctattat
    17041 tgccaatgta gctggttttt caaaacaaga gtatgcagct gtttctcatg ggatttccaa
    17101 ggcaactaat gtaaaagcta tcgagctcaa tatttcttgt cccaatgttg accactgtaa
    17161 tcatggactt ttgattggtc aagatccaga tttggcttat gatgtggtga aagcagctgt
    17221 ggaagcctca gaagtgccag tttatgtcaa attaaccccg agtgtgaccg atatcgttac
    17281 tgtcgcaaaa gctgcagaag atgcgggagc aagtggcttg actatgatca atactctggt
    17341 tggaatgcgc tttgacctca aaaccagaaa accaatcttg gccaatggaa caggtggaat
    17401 gtcaggtcca gcagtctttc cagtagccct caaactcatc cgccaagtag cccaaacaac
    17461 agacctgcct atcattggaa tggggggagt ggattcggct gaagctgccc tagaaatgta
    17521 tctggctggg gcatctgcta tcggagttgg aacagctaac tttaccaatc cttatgcctg
    17581 ccctgacatc atcgaaaatt taccaaaagt catggataaa tacggtatta gcagtctgga
    17641 agaactccgt caggaagtaa aagagtctct gaggtaaact gcaatcaatc tgttcttgat
    17701 tttttattag tttgtaatat gaatttagga gaattttggt acaataaaat aaataagaac
    17761 agaggaagaa ggttaatgaa gaaagtaaga tttatttttt tagctctgct atttttctta
    17821 gctagtccag agggtgcaat ggctagtgat ggtacttggc aaggaaaaca gtatctgaaa
    17881 gaagatggca gtcaagcagc gaatgagtgg gtttttgata ctcattatca atcttggttc
    17941 tatataaaag cagatgctaa ctatgctgaa aatgaatggc taaagcaagg tgacgactat
    18001 ttttacctca aatctggtgg ctatatggcc aaatcagaat gggtagaaga caagggagcc
    18061 ttttattatc ttgaccaaga tggaaagatg aaacgaaatg cttgggtagg aacttcctat
    18121 gttggtgcaa caggtgccaa agtaatagaa gactgggtct atgattctca atacgatgct
    18181 tggttttata tcaaagcaga tggacagcac gcagagaaag aatggctcca aattaaaggg
    18241 aaggactatt atttcaaatc cggtggttat ctactgacaa gtcagtggat taatcaagct
    18301 tatgtgaatg ctagtggtgc caaagtacag caaggttggc tttttgacaa acaataccaa
    18361 tcttggtttt acataaaaga aaatggaaac tatgctgata aagaatggat tttcgagaat
    18421 ggtcactatt attatctaaa atccggtggc tacatggcag ccaatgaatg gatttgggat
    18481 aaggaatctt ggttttacct caagtttgat ggcaaaatgg ctgaaaaaga atgggtctac
    18541 gattctcata gtcaagcctg gtactacttc aaatccggtg gttacatgac agccaatgaa
    18601 tggatttggg ataaggaatc ttggttttat ctcaaatctg atgggaaaat agctgaaaaa
    18661 gaatgggtct acgattctca tagtcaagct tggtactact tcaaatccgg tggttacatg
    18721 acagccaatg aatggatttg ggataaggaa tcttggtttt acctcaagtc tgatggcaaa
    18781 atggctgaaa aagaatgggt ctacgattct catagtcaag cctggtacta cttcaaatct
    18841 ggtggctaca tggcgaaaaa tgagacagta gatggttatc agcttggaag cgatggtaaa
    18901 tggcttggag gaaaagctac aaataaaaat gctgcttact atcaagtagt gcctgtcaca
    18961 gccaatgttt atgattcaga tggtgaaaag ctttcctata tatcgcaagg tagtgtcgta
    19021 tggctagata aggatagaaa aagtgatgac aagcgcttgg ctattactat ttctggtttg
    19081 tcaggctata tgaaaacaga agatttacaa gcgctagatg ctagtaagga ctttatccct
    19141 tattatgaga gtgatggcca ccgtttttat cactatgtgg ctcagaatgc tagtatccca
    19201 gtagcttctc atctttctga tatggaagta ggcaagaaat attattcggc agatggcctg
    19261 cattttgatg gttttaagct tgagaatccc ttccttttca aagatttaac agaggctaca
    19321 aactacagtg ctgaagaatt ggataaggta tttagtttgc taaacattaa taatagcctt
    19381 ttggagaaca agggcgctac ttttaaggaa gccgaagaac attatcatat caatgccctt
    19441 tatctccttg cccatagtgc cctagaaagt aactggggaa gaagtaaaat tgccaaagat
    19501 aagaataatt tctttggcat tacagcctat gatacgaccc cttacctttc tgccaagaca
    19561 tttgatgatg tggataaggg aattttaggt gcaaccaagt ggattaagga aaattatatc
    19621 gataggggaa gaactttcct tggaaacaag gcttctggta tgaatgtgga atatgcttca
    19681 gacccttatt ggggcgaaaa aattgctagt gtgatgatga aaatcaatga gaagctaggt
    19741 ggcaaagatt agtactataa gtgaatatga tttgagtgaa tagtaagtta aaaatcctga
    19801 tttcaagtaa aatcaggatt ttttcatgga tgcaattttt ttggagtctg gtgtgacgcg
    19861 gagggtcttt tgtcctgtgt aagtgacaaa gccgggtttt ccaccagttg gtttattgag
    19921 ttttttgact tcaatcatat ctacctgcac cagattcgac aggcgccctt gagagaagta
    19981 ggcagctaac tctgctgcgt ctgtcttgac tgcatcagat gggtcaagat ttcctgagat
    20041 gacaacatgg cttccaggaa tgtccttagc atggaaccaa agttcctcct tgcgggccat
    20101 tttaaaggtc aattcctcat tttgaagatt gtttcgtccg acatagatga tggttttgcc
    20161 atcgcttgct agatattgtt ctagtttttt gcgtttctgg attttctccc gttgtcttct
    20221 gcggataaaa cctgtttgaa tcaattcttc acggatttca gcgatttctt ccagtccagc
    20281 ttggttgagg acggtttcta cactttccag atagagaata gtggctttgg tttcttcaat
    20341 caaatcagtc aagtatttga cagcttcttt gagtttctga taccgtttaa aatagcgttg
    20401 ggcattctgg ttgggagtca gagccttatc aagcgcaatc atgataggtt ggttggtata
    20461 gtagttgtct aggataacct ggtcttggtc gttaggcact tggtgtagga aggttgtcag
    20521 caattctcct ttttgacgaa attcttcagc gttgtctgtc gccagtaact ctttttcctg
    20581 ttttttgagt ttgtgtcggt ttttctgaag ttcattttca acacgacgaa tcagttcact
    20641 ggcctgctgt ttgacgcggt cgcgctcagc cttatcctta tagtaggtgt ccaacaaatc
    20701 agaaagattt gcaaaaggct ctcccacctg atttgcaaaa ggaactggac tgaaggaagt
    20761 ctcagtcaag catggcttgg tttcttgatt gaaaaaattt cggaaagcgg aaagtttttc
    20821 actaaccagt atcctttcca attcatttgc agtatcgcgt cccagacctt gaaagaggct
    20881 ttgaagattt tttgctgtta gttcttgggt ttgcaggatt tcaaagagct tttcatcttt
    20941 gatagtaaaa ggattgagag attctgtact tggcggagcg atataggtcg atcctggaag
    21001 taaggtgcgg tagctatttt gtgaaaaacc gacgtgtttg ataacttcga ggattttatg
    21061 actgctttta tcgaccagta gaatattact gtgtttcccc ataatttcaa taatcaaggt
    21121 agcctggata tggtctccaa tctcgttttt attggaaact gtaatttcca caatacggtc
    21181 attttccact tgctcaatcg actcaatcag ggccccctgc aaatactttc tcaaaaccat
    21241 gataaaggta gaaggttgag ctggattttc aaaagtcgtt tgggtcagct gaatgcgtcc
    21301 aaaaactgga tgggcagaaa ggagcaggcg atggctttgg cgattgctgc ggatttgcaa
    21361 gaccaactct tgttcaaaag gctgattgat tttctggatg cgaccattca ctaattcgct
    21421 tcgcaattcc tcaactatgt ggtgtaaaaa aaatccgtca aatgacatcg ttctctcctt
    21481 gtgattgtat tccatagtat tatatcaaaa aggtagaata aaatcatgga aatgtggtat
    21541 aataaagcca agtaaagaga aacgagaagc acatgtatat tgaaatggta gatgaaactg
    21601 gtcaagtttc aaaagaaatg ttgcaacaaa cccaagaaat tttggaattt gcagcccaaa
    21661 aattaggaaa agaagacaag gagatggcag tcacttttgt gaccaatgag cgtagtcatg
    21721 aacttaatct ggagtaccgt gacaccgacc gtccgacaga tgtcatcagc cttgagtata
    21781 aaccagaatt ggaaattgcc tttgacgaag aggatttgct tgaaaatcca gaattggcag
    21841 agatgatgtc tgagtttgat gcctatattg gggaattgtt catctctatc gataaggctc
    21901 atgagcaggc cgaagaatat ggtcacagct ttgagcgtga gatgggcttc ttggcagtac
    21961 acggcttttt acatattaac ggctatgatc actatactcc ggaagaagaa gcggagatgt
    22021 tcggtttaca agaagaaatt ttgacagcct atggactcac aagacaataa acgaaaatgg
    22081 aaaaatcgtg acttgatatc cagtttagaa tttgccatca cagggatttt tactgctatc
    22141 aaggaagaac gaaatatgcg aaaacatgca gtgacggctc tagtggtcat ccttgcaggt
    22201 tttgtttttc aggtgtcacg aatcgaatgg ctctttcttc tattgagtat tttcttggta
    22261 gtagcctttg agattatcaa ctctgctatt gaaaatgtgg tggatttggc cagtcactat
    22321 cacttttcca tgctggctaa aaatgccaag gatatggcgg ccggcgcggt attagtggtt
    22381 tctctttttg cagccttaac aggcgcattg atttttctcc cacgaatctg ggatttatta
    22441 ttttaaacag taagaggaaa ttatgacttt taaatcaggc tttgtagcca ttttaggacg
    22501 tcccaatgtt gggaagtcaa cctttttaaa tcacgttatg gggcaaaaga ttgccatcat
    22561 gagtgacaag gcgcagacaa cgcgcaataa aatcatggga atttacacga ctgataagga
    22621 gcaaattgtc tttatcgaca caccagggat tcacaaacct aaaacagctc tcggagattt
    22681 catggttgag tctgcctaca gtacccttcg cgaagtggat accgttcttt tcatggtgcc
    22741 tgctgatgaa gcgcgtggta agggggacga tatgattatc gagcgtctca aggctgccaa
    22801 ggttcctgtg attttggtgg tgaataaaat cgataaggtc catccagacc agctcttgtc
    22861 tcagattgat gacttccgta atcaaatgga ctttaaggaa attgttccaa tctcagccct
    22921 tcagggaaat aacgtgtctc gtctagtgga tattttgagt gaaaatctgg atgaaggttt
    22981 ccaatatttc ccgtctgatc aaatcacaga tcatccagaa cgtttcttag tttcagaaat
    23041 ggttcgcgag aaagtcttgc acctaactcg tgaagagatt ccgcattctg tagcagtagt
    23101 tgttgactct atgaaacgag acgaagagac agacaaggtt cacatccgtg caaccatcat
    23161 ggtcgagcgc gatagccaaa aagggattat catcggtaaa ggtggcgcta tgcttaagaa
    23221 aatcggtagt atggcccgtc gtgatatcga actcatgcta ggagacaagg tcttcctaga
    23281 aacctgggtc aaggtcaaga aaaactggcg cgataaaaag ctagatttgg ctgactttgg
    23341 ctataatgaa agagaatact aagtagaggt aggctcatgc ctgcttcttg tttttacaga
    23401 aggaggactt atgcctgaat tacctgaggt tgaaaccgtt tgtcgtggct tagaaaaatt
    23461 gattatagga aagaagattt cgagtataga aattcgctac cccaagatga ttaagacgga
    23521 tttggaagag tttcaaaggg aattgcctag tcagattatc gagtcaatgg gacgtcgtgg
    23581 aaaatatttg cttttttatc tgacagacaa ggtcttgatt tcccatttgc ggatggaggg
    23641 caagtatttt tactatccag accaaggacc tgaacgcaag catgcccatg ttttctttca
    23701 ttttgaagat ggtggcacgc ttgtttatga ggatgttcgc aagtttggaa ccatggaact
    23761 cttggtgcct gaccttttag acgcctactt tatttctaaa aaattaggtc ctgaaccaag
    23821 cgaacaagac tttgatttac aggtctttca atctgccctt gccaagtcca aaaagcctat
    23881 caaatcccat ctcctagacc agaccttggt agctggactt ggcaatattt atgtggatga
    23941 ggttctctgg cgagctcagg ttcatccagc tagatcttcc cagactttga cagcagaaga
    24001 agcgacagct attcatgacc aaaccattgc tgttttgagc caggctgttg aaaaaggcgg
    24061 ttccaccatt cggacttata ccaatgcctt tggggaagat ggaagcatgc aggactttca
    24121 tcaggtctat gataagactg gtcaagagtg tgtacgctgt ggtaccatca ttgagaaaat
    24181 tcaactaggc ggacgaggca cccacttttg tccaaactgt caaaggaggg actgatgaga
    24241 aaaatcatcg gaatcactgg gggaattgcc tctggtaagt caactgtgac aaattttcta
    24301 agacagcaag gctttcaagt agtggatgcc gacgcagtcg tccaccaact acagaaacct
    24361 ggtggtcgtc tgtttgaggc tctagtacag cactttgagc aagaaatcat tcttgaaaac
    24421 ggagaactca atcgccctct cctagctagt ctcatctttt caaatcctga agagcaaaaa
    24481 tggtcgaagc aaattcaagg ggagattatc cgtgaggaac tggctacttt gagagaacag
    24541 ttggctcaga cagaagagat tttcttcatg gatattcccc tactttttga gcaggactac
    24601 agcgattggt ttgctgagac ttggttggtc tatgtggacc gagatgccca agtagaacgc
    24661 ttaatgaaaa gggaccagtt gtccaaagat gaagctgagt ctcgtctggc agcccagtgg
    24721 cctttagaaa aaaagaaaga tttggccagc caggttcttg ataataatgg caatcagaac
    24781 cagcttctta atcaagtgca tatccttctt gagggaggta ggcaagatga cagagattaa
    24841 ctggaaggat aatctgcgta ttgcctggtt tggtaatttt ctgacaggag ccagtatttc
    24901 tttggttgta ccttttatgc ccatcttcgt ggaaaatcta ggtgtaggga gtcagcaagt
    24961 cgctttttat gcaggcttag caatttctgt ctctgctatt tccgcggcgc tcttttctcc
    25021 tatttggggt attcttgctg acaaatacgg ccgaaaaccc atgatgattc gggcaggtct
    25081 tgctatgact atcactatgg gaggcttggc ctttgtccca aatatctatt ggttaatctt
    25141 tcttcgttta ctaaacggtg tatttgcagg ttttgttcct aatgcaacgg cactgatagc
    25201 cagtcaggtt ccaaaggaga aatcaggctc tgccttaggt actttgtcta caggcgtagt
    25261 tgcaggtact ctaactggtc cctttattgg tggctttatc gcagaattat ttggcattcg
    25321 tacagttttc ttactggttg gtagttttct atttttagct gctattttga ctatttgctt
    25381 tatcaaggaa gattttcaac cagtagccaa ggaaaaggct attccaacaa aggaattatt
    25441 tacctcggtt aaatatccct atcttttgct caatctcttt ttaaccagtt ttgtcataca
    25501 attttcagcc caatcgatcg gccctatttt ggctctttat gtacgcgact tagggcagac
    25561 agagaatctt ctttttgtct ctggtttgat tgtgtccagt atgggctttt ccagcatgat
    25621 gagtgcagga gtcatgggca agctaggtga caaggtgggc aatcatcgtc tcttggttgt
    25681 cgcccagttt tattcagtca tcatctatct cctctgtgcc aatgcctcta gcccccttca
    25741 actaggactc tatcgtttcc tctttggatt gggaaccggt gccttgattc ccggggttaa
    25801 tgccctactc agcaaaatga ctcccaaagc cggcatttcg agggtctttg ccttcaatca
    25861 ggtattcttt tatctgggag gtgttgttgg tcccatggca ggttctgcag tagcaggtca
    25921 atttggctac catgctgtct tttatgcgac gagcctttgt gttgccttta gttgtctctt
    25981 taacctgatt caatttcgaa cattattaaa agtaaaggaa atctagtgcg agtaaaaatc
    26041 aatctcaaat gctcctcttg tggcagtatc aattacctaa ccagtaaaaa ttcaaaaacc
    26101 catccagaca agattgaggt tttaaagtat tgtcccaagg aaaaaaaagt aaccctacat
    26161 cttgaatcta agtagatttt atggtaaaat aatagggatt ttaaggagtt tgatatgtat
    26221 aacctattat taaccatttt attagtatta tctgttgtga ttgtgattgc aattttcatg
    26281 caaccaacca aaaaccaatc cagcaatgta tttgatgcca gttcaggtga tttgtttgaa
    26341 cgcagtaaag ctcgcggttt tgaagctgta atgcagcgtt tgacagggat tttagtcttt
    26401 ttctggctag ccattgcctt agcattgacg gtattatcaa gtagataaga aaataatggg
    26461 caggactagg tctttgcctc tttttatttt taaaggatgt ttgagaaggt tttacagtaa
    26521 aagaaaatta aaaaatctag aaagaaaata tgaaagatag aataaaagaa tatttacaag
    26581 acaagggaaa ggtgactgtt aatgatttgg ctcaggcttt gggaaaagac agttccaagg
    26641 attttcgtga gttgattaaa accttgtcct taatggaaag aaagcaccaa attcgttttg
    26701 aagaagatgg tagtctgaca ttagaaatta agaaaaaaca tgagattacc ctcaagggga
    26761 tttttcatgc ccataaaaat ggctttggct ttgttagtct ggaaggcgag gaggacgacc
    26821 tttttgtagg gaaaaatgat gtcaactatg ctattgatgg tgataccgtc gaggtagtga
    26881 ttaagaaagt cgctgaccgc aataagggaa cagcagcaga agccaaaatt attgatatcc
    26941 tagaacacag tttgacaaca gttgtcgggc aaatcgttct ggatcaggaa aaacctaagt
    27001 atgctggcta tattcgttca aaaaatcaga aaatcagtca accgatttat gttaagaaac
    27061 cagccctaaa attagaagga acagaagttc tcaaggtctt tatcgataaa tacccaagca
    27121 agaaacatga tttctttgtc gcgagtgttc tcgatgtggt gggacactca acggatgtcg
    27181 gaattgatgt tcttgaggtt ttggaatcaa tggacattgt atccgagttt ccagaagctg
    27241 ttgttaagga agcagaaagt gtgcctgatg ctccgtctca aaaggatatg gaaggtcgtc
    27301 tggatctaag agatgaaatt acctttacca ttgacggtgc ggatgccaag gacttggacg
    27361 atgcagtgca tatcaaggct ctgaaaaatg gcaatctgga gcttggggtt cacatcgcag
    27421 atgtttctta ttatgtgacc gaggggtctg cccttgacaa ggaagccctt aaccgtgcga
    27481 cttctgttta cgtgacagac cgagtggtgc caatgcttcc agaacgacta tcaaatggca
    27541 tctgctctct caatccccaa gttgaccgcc tgacccagtc tgctattatg gagattgata
    27601 aacatggtcg tgtggtcaac tataccatta cacaaacagt tatcaagacc agttttcgta
    27661 tgacctatag cgatgtcaat gatatcctag ctggcgatga agaaaagaga aaagaatatc
    27721 ataaaattgt accaagtatc gaactcatgg ccaagcttca tgaaacttta gaaaacatgc
    27781 gtgtgaaacg tggagctctc aattttgata ccaatgaagc gaagatttta gtggataaac
    27841 aaggtaagcc tgttgatatc gttcttcggc agcgtggcat tgccgagcgg atgattgagt
    27901 cttttatgtt gatggctaat gaaacagttg ccgaacattt cagcaagttg gatttgcctt
    27961 ttatctatcg aattcacgag gagcctaagg ctgaaaaggt tcagaagttt attgattatg
    28021 cttcgagttt tggcttgcgc atttatggaa ctgccagtga gattagtcag gaggcacttc
    28081 aagacatcat gcgtgctgtt gagggagaac cttatgcaga tgtattgtcc atgatgcttc
    28141 ttcgctctat gcagcaggct cgttattcgg agcacaatca cggccactat ggactagctg
    28201 ctgactatta tactcacttt accagtccaa ttcgtcgtta tccagacctt cttgttcacc
    28261 gtatgattcg ggattacggc cgttctaagg aaatagtaga gcattttgag caagtgattc
    28321 cagagattgc gacccagtct tccaaccgtg aacgtcgtgc catagaagct gagcgtgaag
    28381 tcgaagccat gaaaaaggct gagtatatgg aagaatacgt gggtgaagag tatgatgcag
    28441 ttgtatcaag tattgtcaaa ttcggtctct ttgtcgaatt gccaaacaca gttgaaggct
    28501 tgattcacat cactaatcta cctgaatttt atcatttcaa tgagcgtgat ttgactcttc
    28561 gtggagaaaa atcaggtatc actttccgag tgggtcagca gatccgtatc cgtgttgaaa
    28621 gagcggataa aatgactgga gagattgatt tttcattcgt acctagtgag tttgatgtga
    28681 ttgaaaaagg cttgaaacag tctagtcgta gtggcatagg gcgtggttcc aatcgtcgtt
    28741 cggataagaa ggaagacaag agaaaatcag gacgctcaaa tgataagcgt aagtattcac
    28801 aaaaagacaa gaagaaaaaa ggaaagaaac ctttttacaa ggaagtagct aagaaaggag
    28861 ccaagcatgg caaagggcga gggaaaggtc gtcgcacaaa ataaaaaggc acgccacgac
    28921 tatacaatcg tagatacgct agaggcaggg atggtcctga ctggaactga aatcaagagt
    28981 gtacgagctg ctcgaattaa tctcaaggat ggctttgctc aagtgaaaaa tggagaagtt
    29041 tggctgagca atgttcatat cgcgccttac gaagagggca atatctggaa ccaggaacca
    29101 gaacgtcgtc gtaaactcct gctccataaa aagcaaattc aaaaattgga acaagagacc
    29161 aaagggacag gaatgacctt agttcccctt aaggtctata taaaagatgg ctacgctaag
    29221 cttcttttag gacttgccaa agggaagcat gactatgaca aacgggagtc tatcaaacgt
    29281 cgtgagcaaa atcgagatat cgcgcgtgtg atgaaagctg ttaatcagcg ataaaaagag
    29341 gaattgaaaa tggaaaaatt agttgcctat aaacgcatgc ctttgtggaa taaacaaaca
    29401 atgcctgaag ctgttcagca aaagcacaat acaaaagttg ggacttgggg gaaaattact
    29461 gtcttgaagg gagctctcaa gtttattgaa ttgacagaag aaggggaagt tctagctgaa
    29521 cacctctttg aagcaggggc agacaatcca atggcccaac ctcaagcctg gcaccgagtg
    29581 gaagctgcca cagatgatgt ggaatggtac ttggaatttt attgtaaacc tgaggattat
    29641 tttgctaaaa aatacaatac caatcctgtt cattcagagg tcctagaggc catgcagaca
    29701 gtgaaacaag ggaaagcttt ggatttgggt tgtggtcagg ggcgtaattc tctttttcta
    29761 gcccagcaag attttgatgt gacggctgta gatcaaaatg gactagctct tgaaatcttg
    29821 caaagcattg tggagcagga agatttggac atgcctgttg gcctttacga tatcaattca
    29881 gctagcattg aacaagaata tgattttatc gtttcaacag ttgttctcat gtttctacaa
    29941 gcggaccgca ttccagctat tattcaaaat atgcaggaga aaaccagtgt tggtggttac
    30001 aaccttatcg tttgtgccat ggacacggag gattatcctt gctcggttaa cttcccattc
    30061 acctttaaag aaggagaact ggcagactat tacaaggatt gggaattggt taagtacaat
    30121 gaaaatccag gccatttgca ccgtcgcgat gagaatggca atcgtattca actacgcttt
    30181 gcgaccttac tagctaagaa aatcaagtaa acatacatga agattaggaa ttttcctgat
    30241 cttttttctt ttttacgaat gatatagaaa aggagggaat tcatgtttgt tgcgagagat
    30301 gctaggggag aattggtaaa tgtgttagag gataaacttg agaagcaagc atacacctgc
    30361 ccagcttgtg gaggccagat ccatttgcgt caaggaccaa gtgtacggac gcattttgcc
    30421 cataaatcct taaaagactg tgattttttc tttgaaaatg aaagtccaga acacctggcc
    30481 aataaggaat ccctctatca ctggttgaaa aaagagacaa aggttcaatt agagtacccg
    30541 ctttcagaac ttaaacagat tgcggatgta tttgtaaatg gcaatctagc tctagaagtt
    30601 cagtgtagtc ccttgcctca gaaagtcctt aaagagcgaa gtgagggcta tcgtagtcag
    30661 ggttaccaag tactgtggtt gctgggtcaa aaactgtggc tcaaggagcg tttgactcgt
    30721 ctacagcaag gttttcttta tttcagtcaa aacatgggct tttatgtttg ggaattagac
    30781 aaggaaaaac aagttttaag actcaaatac ctgatttacc aggatctccg cggtaaactc
    30841 cattatcaaa tcaaggaatt ttcctatggt caaggtagtt tattggaaat attgcgtctt
    30901 ccctataaga gacaaaaaat atctcatttt acagtttctg aggacaagga catctgtcgc
    30961 tatatccggc aacaacttta ttatcaaaat ctcttttgga tgaaagaaca agcagaagcc
    31021 tatcaaaagg gagaaaatat cctgacttat ggactgaaag aatggtatcc acaaattcga
    31081 ccaatagtgg gcaaattttt ccagattgaa caagacttga ctagctatta tcagcacttt
    31141 tatacctatt accaaaaaaa tcctcaaaat gattggcaaa agctttatcc accagccttt
    31201 tatcagcaat atttcttgaa aaatatggta gaatagaaag gatggaggaa tctaatggta
    31261 ttacaaagaa atgaaataaa tgaaaaagat acatgggatc tatcaacgat ctacccaact
    31321 gaccaggctt gggaagaagc cttaaaagat ttaacagaac aattggagac agtagcccag
    31381 tatgaaggcc atctcttgga tagtgcggat aacctactag aaatcactga attttctctt
    31441 gaaatggaac gccagataga gaagctttac gtttatgctc atatgaagaa tgaccaggat
    31501 acacgtgaag ctaagtatca agagtactat gccaaggcca tgacactcta cagccagtta
    31561 gaccaagcct tttcattcta tgagcctgaa tttatggaga ttagcgaaaa gcagtatgct
    31621 gactttttag aagctcaacc aaagctgcag gtttatcaac actattttga caagctcttg
    31681 caaggcaagg atcacgttct ttcacaacgt gaagaagaat tattggctgg agctggagaa
    31741 atctttggtt cagcaagtga aaccttcgct atcttggaca atgcggatat tgtgttccct
    31801 tatgtcctag acgatgatgg taaagaagtt cagctatctc atgggactta cacacgtttg
    31861 atggagtcta aaaaacgtga ggttcgccgt ggtgcctatc aagctcttta tgcgacttac
    31921 gaacaattcc aacacaccta tgccaaaacc ttgcaaacca atgttaaggt gcaaaattac
    31981 cgtgctaaag ttcgtaacta caagagtgct cgtcatgcag ccctcgcagc gaattttgtt
    32041 ccagaaagtg tttatgacaa tttggtagca gcagttcgca agcatttgcc actcttacat
    32101 cgctatcttg agcttcgttc aaaaatcttg gggatttcag atctcaagat gtacgatgtc
    32161 tacacaccgc tttcatctgt tgaatacagt tttacctacc aagaagcctt gaaaaaagca
    32221 gaagatgctt tggcagtctt gggtgaggat tacttgagcc gtgttaaacg tgccttcagc
    32281 gagcgttgga ttgatgttta cgaaaatcaa ggcaagcgtt caggtgccta ctctggtggt
    32341 tcttacgata ccaatgcctt tatgcttctc aactggcagg acaatctgga caatctcttt
    32401 actcttgttc atgaaacagg tcacagtatg cattcaagct atactcgtga aactcagcct
    32461 tatgtttacg gggattactc tatctttttg gctgagattg cctcaactac caatgaaaat
    32521 atcttgacgg agaaattatt ggaagaagtg gaagacgacg caacacgctt tgctattctc
    32581 aataacttcc tagatggttt ccgtggaaca gttttccgcc aaactcaatt tgctgagttt
    32641 gaacacgcca ttcaccaagc agatcaaaat ggggaggtct tgacaagcga tttcctaaat
    32701 aaactctacg cagacttgaa ccaagagtat tatggtttga gtaaggaaga caatcctgaa
    32761 atccaatacg agtgggctcg cattccacac ttctactata actactatgt atatcaatat
    32821 tcaactggct ttgcggccgc ctcagccttg gctgaaaaaa ttgtccatgg tagtcaagaa
    32881 gaccgtgacc gctatatcga ctacctcaag gcaggtaagt cggactatcc acttaatgtc
    32941 atgagaaaag ctggtgttga tatggagaag gaagactacc tcaacgatgc ctttgcagtc
    33001 tttgaacgcc gtttaaatga gtttgaagcc cttgttgaaa aattaggatt ggcataaaat
    33061 ggttgaatcg tatagtaaga atgctaacca taacatgcgt cgtcctgtcg tcaaagaaga
    33121 aattgtagac ttgatgcgtc agcgtcaaaa gcaggtcaca ggtttcttga aagaattgga
    33181 agactttgcc cgcaaggaaa atattcctat tattccccat gaaacggttg cttatttccg
    33241 ttttcttatg gaaaccatgc agcctaaaaa tattctggaa attgggacgg ctatcggttt
    33301 ttcagctctc ttgatggctg aacatgcgcc aaatgctaag attacaacta ttgatcgtaa
    33361 tccagaaatg attggttttg ccaaggaaaa ttttgcccag tttgacagtc gcaagcaaat
    33421 cactctccta gagggagatg cggtggatgt cttatctaca ctgacagagt cttatgattt
    33481 cgtatttatg gattctgcca agtctaaata catcgtcttt ctgccagaaa tcctcaaaca
    33541 tttggaagtt ggtggtgtgg ttgtcttgga tgatattttt caaggtggtg atgttgccaa
    33601 ggatattatg gaagtccgtc gtggtcagcg aaccatttat cgaggccttc aaaaattatt
    33661 tgatgcaacc ttagacaatc cagaactcac cgcaacatta gtgcctttag gagatggtat
    33721 tctcatgctt cgtaaaaatg tagcagatgt tcaactgtct gaaagcgaat gattttcaga
    33781 aaaatttaag aaaaaatagt aaaatagata gagtaacact tatctcaaag gagtagacat
    33841 gaagaaaaaa ttattggcag gtgccatcac actattatca gtagcaactt tagcagcttg
    33901 ttcgaaaggg tcagaaggag cagaccttat cagcatgaaa ggggatgtca tcacagaaca
    33961 tcaattttat gagcaagtga aaaacaaccc ttcagcccaa caagtcttgt taaatatgac
    34021 catccaaaaa gtttttgaaa aacaatatgg ctcagagctt gatgataaag aggttgatga
    34081 tactattgcc gaagaaaaaa aacaatatgg cgaaaactac caacgtgtct tgtcacaagc
    34141 aggtatgact cttgaaacac gtaaagctca aattcgtaca agtaaattag ttgagttggc
    34201 agttaagaag gtagcagaag ctgaattgac agatgaagcc tataagaaag cctttgatga
    34261 gtacactcca gatgtaacgg ctcaaatcat ccgtcttaat aatgaagata aggccaaaga
    34321 agttctcgaa aaagccaagg cagaaggtgc tgattttgct caattagcca aagataattc
    34381 aactgatgaa aaaacaaaag aaaatggtgg agaaattacc tttgattctg cttcaacaga
    34441 agtacctgag caagtcaaaa aagccgcttt cgctttagat gtggatggtg tttctgatgt
    34501 gattacagca actggcacac aagcctacag tagccaatat tacattgtaa aactcactaa
    34561 gaaaacagaa aaatcatcta atattgatga ctacaaagaa aaattaaaaa ctgttatctt
    34621 gactcaaaaa caaaatgatt caacatttgt tcaaagcatt atcggaaaag aattgcaagc
    34681 agccaatatc aaggttaagg accaagcctt ccaaaatatc tttacccaat atatcggtgg
    34741 tggagattca agctcaagca gtagtacatc aaacgaatag tccaaatcaa tgagtcaggg
    34801 aaaaaactct acttcaggaa aaaatgaagc aaacattccc acaataaaac gcgtagtaca
    34861 aggtttgtac tgacccccaa aagttagaca aataatttat ccgaaggatt tagttctgta
    34921 ttgcacaggg ctaagtcctt ttagttttac cttaattctc ttgttgttgt aataatcaat
    34981 atagtctata atggcttgtt ccaattgatt aagtgattta aatgttttct catagccata
    35041 aaacatttcg gattttaaaa taccaaagaa agattccatc ctaccgttgt cttggctgtt
    35101 tcccttgcgt gacatagatg cttgaattcc cttactctct aggaaccgat gataagaatc
    35161 gtgttggtat tgccagtctt ggtcactatg gagaatcgta ttctcgtagt gcttctcttt
    35221 gaatgcctgt tccaacatta acgatcaatc aatttaatca tgtacctaat attagaattg
    35281 tttatctcaa atttatttga aagcttctct aagctatatc cttgttttct aagttcatag
    35341 atctgaactt tatcatcata agttaatttc ataataaaaa cactccaaaa gttagatttt
    35401 ttctgtctaa cttttggggt gcagttcatt taacacctga taatatgcgt tttttttatt
    35461 ttaaagactt tttgaccagc ctcatttttt aacttgatac tcagtgaaaa gcaaagatta
    35521 aactaggaag ctagctgtag gctgctcaaa gaacagcttt gaggttgcag ataaaacttg
    35581 tgaggtaacc aacatatata atgtgaagct gacgtggttt gaatagattt tagaagggta
    35641 tgagtctgga agttttaatg gataatgcaa gattccatag aatgggtaag ctagagttct
    35701 tatgtgaaga gtttgggcat aaacttttac cttttcctcc ctactcatct tagtatagaa
    35761 aagtgaatct aaaatagtac ataactgctt ctaaaacatt cttataaatt gatttaaatt
    35821 ctcaaatcat attattcagt tcttatttca ttttgctcta caatcctgtt gagaagacac
    35881 gtgttcatat caaaaaaggt attggcaagt tgcaatacct ttttacgagg ctcttttatc
    35941 ttatttttgt ttcaactgac tatatctcct atggttctag ttcagaaggc taggctataa
    36001 ttatgattga taagaagtat cattccaagt attgagagtg aatgtttcaa aatcatgggt
    36061 ttctataatg gtcaggctgg catttgctag accgccatct ttacgaagaa gtggttcttt
    36121 atagcctagg agagtacgaa gactggcagt aagattggcg ccgtgtccga caattagaat
    36181 acgttcagct ggactatctt ttaatgattt gataaattgg atggtccgtt gagttgtact
    36241 atagagggat tcggctccga acattcgagt gtcaaattga gcaagatttg aacgaaaagc
    36301 ctggatttgt tgcgggtaaa tagcttccaa ggttgcaatt ttcaaacctt ctaacttccc
    36361 aagttgccat tcacggagat taggaacgat ttctaaagaa cagggggtat agagttgact
    36421 ttggataatc tcagcagatt tgaccgctcg aggtaaatca cttgaataaa tctgatcaaa
    36481 aggaatttcc ttgagatact gaccaagtcg ttttagggtt tcaatggatt caggaagaag
    36541 aggagaatca ccactagcac cttgaaaacg accttcttgg ttccagaggg tacgaccgtg
    36601 gcggacaaag tagagtttca ttacttgatg tcctccaaaa tatctacaaa gtctgccttt
    36661 acaaagctag ccaagtcttg tggcgcgacg ataatgctgt gtccgacttc gcctgcagag
    36721 acaatcattt gatccaaatc tagagcaatt ttatcgataa aaatgggata attgtgtttc
    36781 tgacgaattc cgacaggatt attggctcca tgaatgtaac cagttgtttt ttctaagtcc
    36841 ttttgtggaa tcatgctcac ttttttattg ccagaaattt tagctagttt cttttcagac
    36901 aagtgctgag tgatagggac aattccgata atcggtccgg tcttgtctcc caaaagcgcc
    36961 aaggttttga aaatctgatc tcgttcataa ccttgaggaa gctctccttc tagggcattg
    37021 atttgaattc cctgatgagg gatagctgct ttagatagga tttgttccac caatgttttt
    37081 ttgattttaa ctttttttgc cattatttat atttatcctc caattgactc atccaaatac
    37141 caagccagat tcccagcgca aagaagaagg cgatgatgac ataaccgaca agtgaaagtc
    37201 ctgtgtattg gatactttca gcgtttcctg catttggaat taagatcaaa agggtacttg
    37261 ataggacgat accgatgatg aaatgataga cgcgtgagtg gtagttgttt aaggcataat
    37321 ccatcaattt tgaaaaaacg atgagagttg cacctgcacc aattccaatc ggaaagaagg
    37381 ttcccaagag atcaaaagtt ttaaaaccag tcaacatagg agcatagagt cccaaaatca
    37441 aaagtaaatt tgatgggctg aggccaggaa ccaagacgcc aagggccaat agtgcgcctg
    37501 ctaggacgaa gttaagaaag ctggcgctta aggttccaac gacaaaattt aaggcataga
    37561 gtcctaatcc agaaatgata aaggttgtcc ataaccaagt taaatcaatc ttgtctcggt
    37621 cagattctcg agttgattct ttgaggaggc taggaactgt accgataata gctcccgcaa
    37681 agctccataa tacaaagacc tgataatttt caagcaggta ttcaatcggg taggaaaata
    37741 agccgattcc tagaagcata ccgatggcaa ctggaataaa gtacaaaaca ttttctttaa
    37801 agtctttaaa gggatgggcc agaaagccaa tcattcgttc atagattcct aagattgctg
    37861 ctagagcccc tccggaaatt cccggtagga taaatccaag agcaattaca atccctttaa
    37921 taacgcgtgc taaccatgag agcatatatt tcctccaact atttctattt caaaaaatcc
    37981 ttactatatt gtatcacaat cagacacaaa aagaaaaagc aaatgataaa caaatgcttt
    38041 taaggtttta aaaaaagttt tcgaaaggtt tcttctttat tttttaaggg agagataacg
    38101 ttgatatcta aatcgtggtc aaagccggca atttttcctt tagatgtgta ttggtgaata
    38161 tcataatcta aatcagtttt aggactgctc tccaaaaatc ctgagtctga gccgtaggac
    38221 ggaatccaaa cagaggtaaa cttgcctgta tcaatactgt gttcttccat gaagtagaca
    38281 ccaacgtaga tgccgatgtt tttagcacct agtgatgcta gttttgctcg aaagttttcg
    38341 acaccttcgt tcatattaga catggttttg tcttccacgt caagccaata gtaactaggg
    38401 ctgtaaggag aggcagcatt gtagaaaact tcggcagcct tttccatttc ttggacactt
    38461 tttccagcta cataagcgta gacagcaact gggacattcc gcttttgaag ttcagtgata
    38521 tgactcttat aggccttgtc tattccattg ataaatgaag catcattttc ttttgtcgtt
    38581 tgagcaccac tgtgaacacg aacaatagca cctgaaatat tttgtgagag ggcatcgtag
    38641 ttgatttctt caggacgctg ccagccagag aggtcaataa tcggtttgtc taagtgtttc
    38701 aaagcctgtg cttcaatctg tgctatattg gattttgttt taaacgattg gttgtcatta
    38761 agtgggcgat tgatgattaa aatgaacatc ataatcccca aaaaactaaa taaaataagt
    38821 ggatgaattt gttttctcat atcttataat tctaccctaa aaatcaaaaa aaatcaaaaa
    38881 aatgggttaa ggaagagact ttagagcatt ttttcattca agagtgcgga atgatttgaa
    38941 atatggtata ataaaaggga atttctacag aaaagagaag attatgtcaa attttgccat
    39001 tattttagca gcgggtaaag ggactcgcat gaaatctgat ttgccaaaag ttttgcacaa
    39061 ggttgcgggt atttctatgt tggaacatgt tttccgtagt gtgggagcta tccaacctga
    39121 aaagacagta acagttgtag gacacaaggc agaattggtt gaggaggtct tggctggaca
    39181 gacagaattt gtgactcaat ctgaacagtt gggaactggt catgcagtta tgatgacaga
    39241 acctatctta gaaggtttgt caggacacac cttggtcatt gcaggagata ctcctttaat
    39301 cactggtgaa agcttgaaaa acttgattga tttccatatc aatcataaaa atgtggccac
    39361 tatcttgact gctgaaacgg ataatccttt tggctatgga cgaattgttc gtaatgacaa
    39421 tgctgaggtt cttcgtattg ttgagcagaa ggatgctaca gattttgaaa agcaaatcaa
    39481 ggaaatcaac actggaacat acgtctttga caacgagcgt ttgtttgagg ctttgaaaaa
    39541 tatcaatacc aataacgctc aaggcgaata ctatattaca gacgtcattg gtattttccg
    39601 tgaaactggt gaaaaagttg gcgcttatac tttgaaagat tttgatgaaa gtcttggggt
    39661 aaatgaccgt gtggcgcttg cgacagctga gtcagttatg cgtcgtcgca tcaatcataa
    39721 acatatggtc aacggtgtta gctttgtcaa tccagaagca acttatatcg atattgatgt
    39781 tgagattgct ccggaagttc aaatcgaagc caatgttacc ttgaaagggc aaacgaaaat
    39841 tggtgctgag actgttttga caaacggtac ttatgtagtg gacagcacta tcggagcagg
    39901 agcggtcatt accaattcta tgattgagga aagtagtgtt gcagacggtg tgacagtcgg
    39961 tccttatgct cacattcgtc caaattcaag tctgggtgcc caagttcata ttggtaactt
    40021 tgttgaggtg aaaggatctt caatcggtga gaataccaag gctggtcatt tgacttatat
    40081 cggaaactgt gaagtgggaa gcaacgttaa tttcggtgct ggaactatta cagtcaatta
    40141 tgacggcaaa aacaaataca agacagtcat tggagacaat gtctttgttg gttcaaattc
    40201 aaccattatt gcaccagtag aacttggtga caattccctc gttggtgctg gttcaactat
    40261 tactaaagac gtgccagcag atgctattgc tattggtcgc ggtcgtcaga tcaataaaga
    40321 cgaatatgca acacgtcttc ctcatcatcc taagaaccag taggagccta tcatggagtt
    40381 tgaagaaaaa acgcttagcc gaaaagaaat ctatcaagga ccaatattta aactggtcca
    40441 agatcaggtt gaattaccag aaggcaaggg aactgcccaa cgggatttga ttttccacaa
    40501 tggggctgtc tgtgttttag cagtaacgga tgaacaaaaa ctgatcttgg tcaagcagta
    40561 ccgcaaagct atcgaggctg tctcttacga aattccagcc ggaaaattgg aagtaggaga
    40621 aaacacagcc cctgtggcag ctgcccttcg tgaattagag gaagaaacag cctatacagg
    40681 gaaattagaa ctcttgtacg atttttattt agctattggc ttttgtaatg agaagttaaa
    40741 actatattta gcaagcgatt tgacaaaagt ggaaaatccg cgtccgcagg atgaggatga
    40801 aaccttggaa gtccttgaag tgagcttaga agaagcgaaa gaattaatcc aatcaggtca
    40861 tatttgtgat gccaagacaa ttatggctgt tcagtattgg gagttgcaga aaaaatagag
    40921 gaggtcagta tgggtaaatc tttattaacg gatgaaatga ttgaaagagc taatagaggc
    40981 gaaaaaattt caggtcctcc tttgctagat gataatgagg agactaagat tttaccaacc
    41041 tcttcttccc gttttggtta tgccaatcct aagaatcatg gttttagcca ggaaaccttg
    41101 aagattcagg tcgaaccatc tattcataaa agccgtcgca ttgaaaatac caagagaaat
    41161 gtcttcaatt ctaagttgaa taaaatctta ttcgcggtca tctttctctt gattttgctt
    41221 gttttagcaa tgaaactttt gtaatagaaa aggaattgaa atgaaaatag gaattattgc
    41281 tgctatgcca gaagaactgg cttatctggt ccagcattta tataatgtcc aggagcaagt
    41341 tgttttgggg aatacctatc atacaggaac cattgcttct catgaagtcg ttcttgtaga
    41401 aagtggaatt ggtaaggtca tgtctgctat gagtgtggcg attttggctg atcatttcca
    41461 ggtggatgcc cttattaata cgggttcagc tggggcagta gcagaaggta tcgctgttgg
    41521 ggatgtcgtg attgctgaca aattagccta tcatgacgtg gatgtcacag cttttggcta
    41581 tgcttatgga caaatggcgc aacaaccgct ttatttcgaa tcagacaaaa cctttgttgc
    41641 tcaaatccaa gagagtttat ctcaattgga ccaaaactgg catcttggtt tgattgctac
    41701 aggagatagt tttgttgcag gaaatgacaa gatagaagcg attaagtccc atttcccaga
    41761 agttttagcc gtggagatgg agggggcagc tattgctcaa gcagcgcata ccctcaatct
    41821 cccagtctta gtcatccgag ctatgagtga caatgccaac catgaagcaa acatcttttt
    41881 tgatgagttt attatcgaag ctggacgtcg ctctgcccaa gtcttgttgg cctttttgaa
    41941 ggctttagat taagcggaaa tttgacagtt tttctagctt atgataagat ttaagtaaag
    42001 aaaagctaga aaacgtttca gaggatatta tgagtattga aatgaccgtc agtgagattg
    42061 cagaggtctt aggattatct cgccaagcaa tcaataaccg tgtcaaagaa ttaccagaag
    42121 aagacacaga taaaaatgac aaaggggtaa cagttgttac cagaagtggc ttgattaagc
    42181 tagaagaaat ctataaaaaa acgatttttg aagatgaacc tgtcagtgaa gatgtcaaac
    42241 aacgtgaact gatggagatt ctagtggatg agaagaatgc agaaattctt cgtctttatg
    42301 aacaattaaa agccaaggat cgtcagttat cagaaaaaga cgagcagatg cgtatcaaag
    42361 accgtcagat tgctgagaaa gacaaacaat tagatcagca acaacaattg acccttcaag
    42421 ccatgaagga tcaagaaaat cttaagctag agctggacca agcaaaagaa gaagtccaat
    42481 ccactaaaaa aggctttttt gctcgtttat ttggaggata atcaaggagc tgtttaggtt
    42541 aaatgctaac ctgatggctt cttttgtttg tgaatagtat agttgattag aacagagaca
    42601 gtagaggaga ggtacagaat ggaacgatta gaagattaca ttgcttttga tttagaattt
    42661 aatcagcacg aaggacaaac acacttgatt caagtatcgg cagtgcgttt tagagatggt
    42721 cgggaaatcg atgcctatga ttcctatgtt cataccagcg tccctctaaa aagctttatc
    42781 aatggtttga ccgggattac agctgagacc ttaaaagatg ctcctccagt tgagaaagtc
    42841 ttagaagaat tccaagagtt tgtgggttct ttgctgatga taggctacaa tgctgctaaa
    42901 agtgatttac ctattttagc agagcatggt ttagactata gccaacagta caaggtggat
    42961 ttgtatgatg aagcttttga acgtcggagt tcagatttac atggtattgc caatctcaaa
    43021 ttgcaaactg ttgcctcatt tcttggattt caaggtcagt ctcataatag tttagaggat
    43081 gctcggatga cggcgcgtgt ttacgaatcc ttcttagagt cggatcaagc tagggaattg
    43141 ttagagacag aaagtagctt atcaaacaat ccttttggtg gcttggactt gtctcaatta
    43201 tttgactagg agtgcctatg aaacctgaaa aacctaaaaa attgggtctt aaacagattt
    43261 acctcaatct tgataaaatc ctctttctat ttttcttgat ttttatgata gtggagtatt
    43321 tgtgggtacc attcaattca tggttggcta gcttcttatt agatcagaca ggttatcttt
    43381 ttatttccta taacaatgtc ttagccatcc ttactcattc tccattgatt agtctagctt
    43441 ttttagcctt gattgtaatt aactttctgg ttgcttattt tcaaatagga ctcctcttta
    43501 ttggtgctcg tcatctcctc tataatgaaa agcgaaggct aattgagtat atccgcaagg
    43561 ttttccatga aagttttgaa tttatgaaaa agctaactgg cgctaaagcc ttgtttatct
    43621 ttttctatat agctatgctg tttcctttta tacggaaaat gctgaagatt tattatctta
    43681 ataaaatcgt cattccagag tttatccaag cttatttaga agataaatat tggatgtggt
    43741 ggctgagcat cctacttcta tctcttatct ttctctatgt ctctgtcaga ttgatgtttg
    43801 cccttccgaa gattgtatat gatcagctga ctgttcgaga agcagtgatg tttagcttgg
    43861 agaaaaccaa gaagagagtt actttttatg cttggaattt attttacatc ttgctcaaag
    43921 cacatttatt attttatctt cctttgattc ctttattatt ggctcaaact ttggtagatg
    43981 atatcactca gagagagtct ctgattcttg gtattttgaa ttttgtcgtg attaaaaatc
    44041 tctattatat ggctctgact tattttttgg ttaaatttgt ttcatttttg acaggaaagg
    44101 agctggatat gcttcctagg agagaaaaag atcacatcgt gcgatggggt gtcatgactt
    44161 gtgccagttt tttctttgcc ttagaaggtt atatttatct ggaggctccc atggttcatc
    44221 tacctcaact tatttctcac cgaggggttt ccaatgcaaa tgggattcaa aatacagtag
    44281 agtccttgga aactacagca caactcaaac cagacttggt ggagacggac gtgcaggaaa
    44341 caaaagatgg gcagtttgtc atgatgcatg atgctaactt gaaaaatcta gcaggtatca
    44401 ataaaagtcc tcaagactta aacttggagg agcttaaagg gattgatatt tttgaaaatg
    44461 gctaccagac taaaatttca agctttgaag attatctcag tcgagccaac gaacttggtc
    44521 aaaaattact aattgaaatt aaaaccagta aaaaagatag tccagacatg atgaaccgct
    44581 ttttagcccg ttatgctgca aagctcaaga tttatggaca tcaaatccag tctttagact
    44641 accatgttgt cgaaaaagta agacagtatg atgccgaact gccagtttat ttcatcatgc
    44701 cctacaattc tgtctttcct aaaacaagag cgacaggata tactatggag tactcaacct
    44761 tggatgaata ttttgtaagc aaactatgga caacggatca gaaactttat gtctggactg
    44821 tcaatgattc agaagctatc agcaaatctc ttcacttagg agtagatgga gtgattacag
    44881 atgatttgga aaaagttcag cgggaaatag aagtagccca agaagatcca gaatatacgg
    44941 atttgctctt gaaaaaagca ttggaattct ttgaatttta gtaataaaaa agaggaacgg
    45001 ttgttcctcc catgataggt aagtattctt gtgaatgctt gcttttttgt ggttgcaatc
    45061 cgtttacgag aattgtttgt attgttcttg tttcaattta ctttatagtg ctttgaagtt
    45121 ggaatgctac actataactt ct
//
LOCUS       DBEJHE010000017        42163 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC4 isolate 671759
            SAMN38261586-rid24793303.denovo.17, whole genome shotgun sequence.
ACCESSION   DBEJHE010000017 DBEJHE010000000
VERSION     DBEJHE010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261586
            Sequence Read Archive: SRR26833752
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 42163)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42163)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576136.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576136.1
            Genome Coverage       :: 109x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 19:48:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,067
            CDSs (total)                      :: 2,029
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 131
            CDSs (without protein)            :: 131
            Pseudo Genes (ambiguous residues) :: 0 of 131
            Pseudo Genes (frameshifted)       :: 64 of 131
            Pseudo Genes (incomplete)         :: 59 of 131
            Pseudo Genes (internal stop)      :: 46 of 131
            Pseudo Genes (multiple problems)  :: 32 of 131
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42163
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261586-rid24793303.denovo.17"
                     /strain="GPSC4"
                     /isolate="671759"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            1..1021
                     /locus_tag="ACL3EZ_001227"
                     /pseudo
     CDS             1..1021
                     /locus_tag="ACL3EZ_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(1064..1705)
                     /gene="plsY"
                     /locus_tag="ACL3EZ_001228"
     CDS             complement(1064..1705)
                     /gene="plsY"
                     /locus_tag="ACL3EZ_001228"
                     /EC_number="2.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008374 - O-acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006654 - phosphatidic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HGR0392799.1"
                     /translation="MITIVLLILAYLLGSIPSGLWIGQVFFQINLREHGSGNTGTTNT
                     FRILGKKAGMATFVIDFFKGTLATLLPIIFHLQGVSPLIFGLLAVIGHTFPIFAGFKG
                     GKAVATSAGVIFGFAPIFCLYLAIIFFGALYLGSMISLSSVTASIAAVIGVLLFPLFG
                     FILSNYDSLFIAIILALASLIIIRHKDNIARIKNKTENLVPWGLNLTHQDPKK"
     gene            1841..3784
                     /gene="parE"
                     /locus_tag="ACL3EZ_001229"
     CDS             1841..3784
                     /gene="parE"
                     /locus_tag="ACL3EZ_001229"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HGR0392800.1"
                     /translation="MSKKEININNYNDDAIQVLEGLDAVRKRPGMYIGSTDGAGLHHL
                     VWEIVDNAVDEALSGFGDRIDVTINKDGSLTVQDHGRGMPTGMHAMGIPTVEVIFTIL
                     HAGGKFGQGGYKTSGGLHGVGSSVVNALSSWLEVEITRDGAVYKQRFENGGKPVTTLK
                     KIGTALKSKTGTKVTFMPDATIFSTTDFKYNTISERLNESAFLLKNVTLSLTDKRTDE
                     AIEFHYENGVQDFVSYLNEDKEILTPVLYFEGEDNGFQVEVALQYNDGFSDNILSFVN
                     NVRTKDGGTHETGLKSAITKVMNDYARKTGLLKEKDKNLEGSDYREGLAAVLSILVPE
                     EHLQFEGQTKDKLGSPLARPVVDGIVADKLTFFLMENGELASNLIRKAIKARDAREAA
                     RKARDESRNGKKNKKDKGLLSGKLTPAQSKNPAKNELYLVEGDSAGGSAKQGRDRKFQ
                     AILPLRGKVVNTAKAKMADILKNEEINTMIYTIGAGVGADFSIEDANYDKIIIMTDAD
                     TDGAHIQTLLLTFFYRYMRPLVEAGHVYIALPPLYKMSKGKGKKEEVAYAWTDGELEE
                     LRKQFGKGATLQRYKGLGEMNADQLWETTMNPETRTLIRVTIEDLARAERRVNVLMGD
                     KVEPRRKWIEDNVKFTLEEATVF"
     gene            3799..4003
                     /locus_tag="ACL3EZ_001230"
                     /pseudo
     CDS             3799..4003
                     /locus_tag="ACL3EZ_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009014166.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-6 DNA methylase"
     gene            4204..6675
                     /gene="parC"
                     /locus_tag="ACL3EZ_001231"
     CDS             4204..6675
                     /gene="parC"
                     /locus_tag="ACL3EZ_001231"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HGR0392801.1"
                     /translation="MSNIQNMSLEDIMGERFGRYSKYIIQDRALPDIRDGLKPVQRRI
                     LYSMNKDSNTFDKSYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQNWKNREILVEMH
                     GNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKKTVPFAWNFDDTEKEPTVLPAAFP
                     NLLVNGSTGISAGYATDIPPHNLAEVIDAAVYMIDHPTAKIDKLMEFLPGPDFPTGAI
                     IQGRDEIKKAYETGKGRVVVRSKTEIEKLKGGKEQIVITEIPYEINKANLVKKIDDVR
                     VNNKVAGIAEVRDESDRDGLRIAIELKKDANTELVLNYLFKYTDLQINYNFNMVAIDN
                     FTPRQVGIVPILSSYIAHRREVILARSRFDKEKAEKRLHIVEGLIRVISILDEVIALI
                     RTSENKADAKENLKVSYDFTEEQAEAIVTLQLYRLTNTDVVVLQEEEAELREKIAMLA
                     AIIGDERTMYNLMKKELREVKKKFATPRLSSLEDTAKAIEIDTASLIAEEDTYVSVTK
                     AGYIKRTSPRSFAASTLEEIGKRDDDRLIFVQSAKTTQHLLMFTSLGNVIYRPIHELA
                     DIRWKDIGEHLSQTITNFETNEEILYVEVLDQFDDATTYFAVTRLGQIKRVERKEFTP
                     WRTYRSKSVKYAKLKDDTDQIVAVAPIKLDDVVLVSQNGYALRFNIEEVPVVGAKAAG
                     VKAMNLKEDDVLQSGFICNTSSFYLLTQRGSLKRVSIEEILATSRAKRGLQVLRELKN
                     KPHRVFLAGAVAEQGFVGDFFSTEVDVNDQTLLVQSNKGTIYESRLQDLNLSERTSNG
                     SFISDTISDEEVFDAYLQEVVTEDK"
     gene            6807..7829
                     /locus_tag="ACL3EZ_001232"
     CDS             6807..7829
                     /locus_tag="ACL3EZ_001232"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004084 - branched-chain-amino-acid
                     transaminase activity [Evidence IEA];
                     GO_process: GO:0009081 - branched-chain amino acid
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HGR0392802.1"
                     /translation="MTVTIDWENLGFSYMKLPYRYLAHFKNGQWDQGELTEDATLHIS
                     ESSPSLHYGQQAFEGLKAYRTKDGSVQLFRPDENAKRLQRTCDRLLMPQVPTDMFVEA
                     CKAVVRANEEYVPPYGTGGTLYLRPLLIGVGDIIGVKPAEEYIFTIFAMPVGNYFKGG
                     LVPTNFLIQDEYDRAAPNGTGAAKVGGNYAASLLPGKMAKSRHFSDVIYLDPSTHTKI
                     EEVGSANFFGITADNEFVTPLSPSILPSITKYSLLYLAEHRLGLTPIEGDVPIDNLDR
                     FVEAGACGTAAVISPIGGIQHGDDFHVFYSETEVGPVTRKLYNELTGIQFGDIEAPEG
                     WIVKVD"
     gene            7885..8589
                     /locus_tag="ACL3EZ_001233"
     CDS             7885..8589
                     /locus_tag="ACL3EZ_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HGR0392803.1"
                     /translation="MVLSTSAILVACGKTDKEADAPTTFSYVYAVDPASLGYSIATRT
                     SRTDVIGNVIDGLMENDKYGNVAPSQKDYDLNSTGWAPSYQDPASYLNIMDPKSGSAM
                     KHLGITKGKDKDVVAKPGLDKYKKLLEDAVSETTDLEKRYEKYAKAQAWSTDSSLLMP
                     TASSGGSPVVSNVVPFSKPYSQVGIKGEPYIFKGMKLQKDIVTTKEYNEVFKKWQKEK
                     LESNSKYQKELEKYIK"
     gene            8654..9343
                     /locus_tag="ACL3EZ_001234"
     CDS             8654..9343
                     /locus_tag="ACL3EZ_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0858 family membrane protein"
                     /protein_id="HGR0392804.1"
                     /translation="MEWIRLIGIAIIVVGFILKFDTIATVVLAGLVTALVSGVSLVEF
                     LEILGKEFSNQRVLTIFMVTLPLVGLSETFGLKQRSIDLIRKIKGLTVGNFYTVYFFI
                     RELAGFFSIRLGGHPQFVRPLVQPMGEAAAESQLGRKLTEVEDETIKARAAANENFGN
                     FFAQNTFVGAGGVLLIGGTLDQLGYESNYAGIASTSIIVAVITLIVVGIYNYLFDKKL
                     ISKKTRGGEQK"
     gene            9340..10263
                     /locus_tag="ACL3EZ_001235"
     CDS             9340..10263
                     /locus_tag="ACL3EZ_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0859 family membrane protein"
                     /protein_id="HGR0392805.1"
                     /translation="MTELAKQLLELTYIVIGCQFLHTAYCSYKDKTNPVRLGTSAFWT
                     LLSITFIGGSYMPNMSIGIIVILLSLLTLFKQVRIGTLPSLDEMKANIESNRLKNKIF
                     IPVMLMAILALVLAQMIPEFSKISISLAALFATISVLVITNSHPKSLLSENNRMTQQV
                     STSGIVPQLLGALGAIFTVAGVGDVISHLISGIVPSDSRFIGVLAYVLGMVLFTMIMG
                     NAFAAFTVITAGVGVPFVFALGANPIVAGALAMTAGYCGTLLTPMAANFNALPAALMD
                     MKDQNGVIKAQAGVALVMIVIHIFLMYFLAF"
     gene            10278..10922
                     /gene="pcp"
                     /locus_tag="ACL3EZ_001236"
     CDS             10278..10922
                     /gene="pcp"
                     /locus_tag="ACL3EZ_001236"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016920 - pyroglutamyl-peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HGR0392806.1"
                     /translation="MKILVTGFNPFGGEKINPALEAVKLLPSEINGAEVRWVEIPTVF
                     YKSSEVLEAEILRYQPDAVLCIGQAGGRTGLTPERVAINQDDARIPDNEGNQPIDTPI
                     RIDGASAYFSSLPIKAMVQAIKKQGLPAVVSNSAGTFVCNHLMYQALYLVDKKFPNMR
                     AGFMHIPYMMEQVVNKPNTAGMSLCDIVRGIEVAIEAIVDYKDKDLQLVGGETH"
     gene            11090..11320
                     /locus_tag="ACL3EZ_001237"
     CDS             11090..11320
                     /locus_tag="ACL3EZ_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000037109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HGR0392807.1"
                     /translation="MSKKDKKIEIQVADAKVNVGKDSFEGYTLTIGKKVIGEIAELDG
                     QFAIIKNGNVDSFYKKLEKAVEILIENYNLAK"
     gene            11370..11450
                     /locus_tag="ACL3EZ_001238"
     tRNA            11370..11450
                     /locus_tag="ACL3EZ_001238"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:11404..11406,aa:Tyr,seq:gta)
     gene            11460..11531
                     /locus_tag="ACL3EZ_001239"
     tRNA            11460..11531
                     /locus_tag="ACL3EZ_001239"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:11492..11494,aa:Gln,seq:ttg)
     gene            11693..12895
                     /gene="rpsA"
                     /locus_tag="ACL3EZ_001240"
     CDS             11693..12895
                     /gene="rpsA"
                     /locus_tag="ACL3EZ_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HGR0392808.1"
                     /translation="MNEFEDLLNSVSQVETGDVVSAEVLTVDATQANVAISGTGVEGV
                     LTLRELTNDRDADINDFVKVGEVLDVLVLRQVVGKDTDTVTYLVSKKRLEARKAWDKL
                     VGREEEVVTVKGTRAVKGGLSVEFEGVRGFIPASMLDTRFVRNAERFVGQEFDTKIKE
                     VNAKENRFILSRREVVEAATAAARAEVFGKLAVGDVVTGKVARITSFGAFIDLGGVDG
                     LVHLTELSHERNVSPKSVVTVGEEIEVKILDLNEEEGRVSLSLKATVPGPWDGVEQKL
                     AKGDVVEGTVKRLTDFGAFVEVLPGIDGLVHVSQISHKRIENPKEALKVGQEVQVKVL
                     EVNADAERVSLSIKALEERPAQEEGQKEEKRAARPRRPRRQERRDFELPETQTGFSMA
                     DLFGDIEL"
     gene            complement(12980..14282)
                     /locus_tag="ACL3EZ_001241"
                     /pseudo
     CDS             complement(12980..14282)
                     /locus_tag="ACL3EZ_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436408.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            14475..14972
                     /locus_tag="ACL3EZ_001242"
     CDS             14475..14972
                     /locus_tag="ACL3EZ_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0033745 - L-methionine-(R)-S-oxide
                     reductase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HGR0392809.1"
                     /translation="MLKSEKQSRYQMLNEELSFLLEGETNVLANLSNASALIKSRFPN
                     TVFAGFYLFDGKELVLGPFQGGVSCIRIALGKGVCGEAAHFQETVIVGDVTTYLNYIS
                     CDSLAKSEIVVPMMKNGQLLGVLDLDSSEIEDYDAMDRDYLEQFVAILLEKTTWDFTM
                     FEEKS"
     gene            14972..16627
                     /gene="dnaX"
                     /locus_tag="ACL3EZ_001243"
     CDS             14972..16627
                     /gene="dnaX"
                     /locus_tag="ACL3EZ_001243"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009360 - DNA polymerase III complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HGR0392810.1"
                     /translation="MYQALYRKYRSQNFSQLVGQEVVAKTLKQAVEQEKISHAYLFSG
                     PRGTGKTSVAKIFAKAMNCPNQVGGEPCNNCYICQAVTDGSLEDVIEMDAASNNGVDE
                     IREIRDKSTYAPSLARYKVYIIDEVHMLSTGAFNALLKTLEEPTQNVVFILATTELHK
                     IPATILSRVQRFEFKSIKTQDIKEHIHYILEKENISSEPEAVEIIARRAEGGMRDALS
                     ILDQALSLTQGNELTTAISEEITGTISLSALDDYVAALSQQDVPKALSCLNLLFDNGK
                     SMTRFVTDLLHYLRDLLIVQTGGENTHHSSVFVENLALPQKNLFEMIRLATVSLADIK
                     SSLQPKIYAEMMTVRLAEIKPEPALSGAVENEIATLRQEVARLKQELSNVGAVPKQVA
                     PAPSRPATGKTVYRVDRNKVQSILQEAVENPDLARQNLIRLQNAWGEVIESLGGPDKA
                     LLVGSQPVAANEHHAILAFESNFNAGQTMKRDNLNTMFGNILSQAAGFSPEILAISME
                     EWKEVRAAFSAKAKSSQTEKEVEESLIPEGFEFLADKVKVEED"
     gene            16655..16849
                     /locus_tag="ACL3EZ_001244"
     CDS             16655..16849
                     /locus_tag="ACL3EZ_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3272 domain-containing protein"
                     /protein_id="HGR0392811.1"
                     /translation="MNKQQFIIMALFTAAETYFFNEAWMTGRYIMAAFWAILLFRNFR
                     VSYVMGKIVDVIDQHFNRKD"
     gene            16999..17769
                     /gene="sufC"
                     /locus_tag="ACL3EZ_001245"
     CDS             16999..17769
                     /gene="sufC"
                     /locus_tag="ACL3EZ_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HGR0392812.1"
                     /translation="MSVLEIKDLHVEIEGKEILKGVNLTLKTGEIAAIMGPNGTGKST
                     LSAAIMGNPNYEVTKGEVLFDGVNILELEVDERARMGLFLAMQYPSEIPGITNAEFLR
                     AAMNAGKEDDEKISVREFITKLDEKMELLNMKEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFALLDEIDSGLDIDALKVVSKGVNAMRGEGFGAMIITHYQRLLNYITPDVVHV
                     MMEGRVVLSGGPELAARLEREGYAKLAEELGYDYKEEL"
     gene            17797..19059
                     /gene="sufD"
                     /locus_tag="ACL3EZ_001246"
     CDS             17797..19059
                     /gene="sufD"
                     /locus_tag="ACL3EZ_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HGR0392813.1"
                     /translation="MTRENIKLFSEMHAEPSWLADLRQKAFDKIETLELPVIERVKFH
                     RWNLGDGTITENEPSANVPDFTALDHHLKLVQVGTQTVFEQTPVELAEQGVVFTDFHS
                     ALEEIPELIEEFFMSSVKYDDDKLAAYHTAYFNSGAVLYIPDNVEITEPIEGIFYQDS
                     DSNVPFNKHIMIIAGKNSKINYLERLESRGEGSAKATANITVEVIARSGAQVKFAAID
                     RLGENVTAYISRRGKLGNDASIDWAIGVMNEGNVVADFDSDLIGNGSHADLKVVALSS
                     GRQVQGIDTRVTNYGCNSIGNILQHGVILEKATLTFNGIGHIIKGAKGADAQQESRVL
                     MLSDQARSDANPILLIDENDVTAGHAASIGQVDPEDMYYLMSRGLDKATAERLVVRGF
                     LGSVIVEIPVKEVRDEMIATIEEKLSKR"
     gene            19070..20296
                     /locus_tag="ACL3EZ_001247"
     CDS             19070..20296
                     /locus_tag="ACL3EZ_001247"
                     /EC_number="2.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0031071 - cysteine desulfurase activity
                     [Evidence IEA];
                     GO_process: GO:0006534 - cysteine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HGR0392814.1"
                     /translation="MLDVEAIRKDFPILDQIVNDEPLVYLDNAATTQKPLVVLKAINS
                     YYEQDNANVHRGVHTLAERATASYEAARETIRKFINAGSTKEVLFTRGTTTSLNWVAR
                     FAEEILTEGDQVLISVMEHHSNIIPWQEACRKTGAELVYVYLKDGALDMEDLRAKLTD
                     KVKFVSLAHASNVLGVVNPIKEITQLAHQVGAIMVVDGAQSTPHMKIDVQDLDLDFFA
                     FSGHKMAGPTGIGVLYGKEKYLEQMSPVEFGGEMIDFVYEQSASWKELPLKFEAGTPN
                     MAGAIGLATAVDYLEKIGMDAVEAHEQELIAYVYPKLQAIEGLTIYGSQDLAQRSGVI
                     AFNLGDLHPHDLATALDYEGVAVRAGHHCAQPLLQYLEVPATARASFYIYNTKADCDK
                     LVDALQKTKEFFNGTF"
     gene            20283..20723
                     /gene="sufU"
                     /locus_tag="ACL3EZ_001248"
     CDS             20283..20723
                     /gene="sufU"
                     /locus_tag="ACL3EZ_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly sulfur transfer protein
                     SufU"
                     /protein_id="HGR0392815.1"
                     /translation="MALSKLDSLYMAVVADHSKNPHHQGKLEDAEQISLNNPTCGDVI
                     NLSVKFDAEDRLEDIAFLNSGCTISTASASMMTDAVLGKTKQEILELATIFSEMVQGQ
                     KDERQDQLGDAAFLSGVAKFPQRIKCATLAWNALKKTIENQEKQ"
     gene            20777..22189
                     /gene="sufB"
                     /locus_tag="ACL3EZ_001249"
     CDS             20777..22189
                     /gene="sufB"
                     /locus_tag="ACL3EZ_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017769002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HGR0392816.1"
                     /translation="MAEERVEPKPIDLGEYKFGFHDDVEPVLSTGKGLNEGVIRELSA
                     AKGEPEWMLEFRLKSYETFKKMPMQTWGADLSEIDFGDLIYYQKPSDKPARSWDDVPE
                     KIKETFERIGIPEAERAYLAGASAQYESEVVYHNMKEEFQKLGIIFTDTDSALKEYPD
                     LFNQYFAKLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDIPLQTYFRINNENIGQFE
                     RTLIIVDEGASVHYVEGCTAPTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVYNL
                     VTKRAKAQKDATVEWIDGNLGAKTTMKYPSVYLDGEGARGTMLSIAFANAGQHQDTGA
                     KMIHNAPHTSSSIVSKSIAKGGGKVDYRGQVTFNKNSKKSVSHIECDTIIMDDLSASD
                     TIPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKELP
                     MEYAVELNRLISYEMEGSVG"
     gene            complement(22420..23661)
                     /gene="pbp3"
                     /locus_tag="ACL3EZ_001250"
     CDS             complement(22420..23661)
                     /gene="pbp3"
                     /locus_tag="ACL3EZ_001250"
                     /EC_number="3.4.16.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase PBP3"
                     /protein_id="HGR0392817.1"
                     /translation="MKKIFLTLLTVSLLGGASTAVAQDFTIAAKHAIAVEANTGKILY
                     EKDATQPVEIASITKLITVYLVYEALENGSITLSTPVDISDYPYQLTTNSEASNIPME
                     ARNYTVEELLEATLVSSANSAAIALAEKIAGSEKDFVDMMRAKLLEWGIQDATVVNTT
                     GLNNETLGDNIYPGSKKDEENKLSAYDVAIVARNLIKKYPQVLEITKKPSSTFAGMTI
                     TSTNYMLEGMPAYRGGFDGLKTGTTDKAGESFVGTTVEKGMRVITVVLNADNQDNNPY
                     ARFTATSSLMDYISSTFTLRKIVQQGDAYQDSKAPVQDGKEDTVTAVAPEDIYLIERV
                     GNQSSQSVQFTPDSKAIPAPLEAGTVVGHLTYEDKDLIGQGYITTERPSFEMVADKKI
                     EKAFFLKVWWNQFVRFVNEKL"
     gene            23764..24873
                     /gene="cozE"
                     /locus_tag="ACL3EZ_001251"
     CDS             23764..24873
                     /gene="cozE"
                     /locus_tag="ACL3EZ_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell elongation protein CozE"
                     /protein_id="HGR0392818.1"
                     /translation="MFRRNKLFFWTTEILLLTIIFYLWRQMGSLINPFVSVLNTIMIP
                     FLLGGFLYYLTNPIVTFLNKVCKLNRLLGILITLCTLVWGMVIGVVYLLPILINQLSS
                     LIISSQTIYSRVQDLIIDLSNYPALQNLDVEATIQQLNLSYVDILQNILNSVSNSVGS
                     VLSALISTVLILIMTPVFLVYFLLDGHKFLPMLERTILKRDRLHIAGLLKNLNATIAR
                     YISGVSIDAIIIGCLAYIGYSIIGLKYALVFAIFSGVANLIPYVGPSIGLIPMIIANI
                     FTDPHRLLIAVIYMLVVQQVDGNILYPRIVGSVMKVHPITILVLLLLSSNIYGVVGMI
                     VAVPTYSILKEISKFLSRLYENHKIMKERERELAK"
     gene            25407..25754
                     /gene="ssrA"
                     /locus_tag="ACL3EZ_001252"
     tmRNA           25407..25754
                     /gene="ssrA"
                     /locus_tag="ACL3EZ_001252"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(25937..26024)
                     /locus_tag="ACL3EZ_001253"
     tRNA            complement(25937..26024)
                     /locus_tag="ACL3EZ_001253"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(25988..25990),aa:Ser,seq:gga)
     gene            26186..26926
                     /locus_tag="ACL3EZ_001254"
     CDS             26186..26926
                     /locus_tag="ACL3EZ_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HGR0392819.1"
                     /translation="MLKTERKQLILEELNQHHVVSLEKLVSLLETSESTVRRDLDELE
                     AENKLRRVHGGAELPHSLQEEETIQEKSVKNLQEKKLLAQKAASLIKEKDVIFIDAGT
                     TTAFLIHELVNKNVTVVTNSIHHAAQLVEKQIPTVMVGGNVKTATDASIGGVALNQIN
                     QLHFDRAFIGMNGVDDGYYTTPDMEEGAVKRAILENAKQTYVLVDSSKIGQTCFAKVA
                     PLKRAIVITSQGHELLQVIKEKTEVIEV"
     gene            26923..27834
                     /gene="pfkB"
                     /locus_tag="ACL3EZ_001255"
     CDS             26923..27834
                     /gene="pfkB"
                     /locus_tag="ACL3EZ_001255"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015605104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008662 - 1-phosphofructokinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HGR0392820.1"
                     /translation="MIYTVTLNPSIDYIVRLDQVKVGSVNRMDSDDKFAGGKGINVSR
                     VLKRLNIPNTATGFIGGFTGKFITDTLAEEEIETRFVQVAEDTRINVKIKADQETEIN
                     GTGPTVEPVQLEELKAILSSLTAEDTVVFAGSSAKNLGNVIYKDLISLTRQTGAQVVC
                     DFEGQTLIDSLDYQPLLVKPNNHELGAIFGVKLESLDEIEKYARELLAKGAQNVIISM
                     AGDGALLVTSEGAYFAKPIKGTVKNSVGAGDSMVAGFTGEFVKSKDAVEAFKWGVACG
                     TATTFSDDLATAEFIKETYGKVEVEKR"
     gene            27831..29783
                     /locus_tag="ACL3EZ_001256"
     CDS             27831..29783
                     /locus_tag="ACL3EZ_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022877 -
                     protein-N(PI)-phosphohistidine-fructose phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-specific PTS transporter subunit EIIC"
                     /protein_id="HGR0392821.1"
                     /translation="MKIQDLLRKDVMLLDLQATEKTAVIDEMIKNLTEHGYVTDFETF
                     KEGILAREALTSTGLGDGIAMPHSKNAAVKEATVLFAKSNKGVDYESLDGQATDLFFM
                     IAAPEGANDTHLAALAELSQYLMKDGFADKLRQATSADQVIELFDQASEKTEELVQAP
                     ANDSGDFIVAVTACTTGIAHTYMAQEALQKVAAEMGVGIKVETNGASGVGNQLTAEDI
                     RKAKAIIIAADKAVEMDRFDGKPLINRPVADGIRKTEELINLALSGDTEVYRAANGAK
                     AATASNEKQSLGGALYKHLMSGVSQMLPFVIGGGIMIALAFLIDGALGVPNENLGNLG
                     SYHELASMFMKIGGAAFGLMLPVFAGYVAYSIAEKPGLVAGFVAGAIAKEGFAFGKIP
                     YAAGGEATSTLAGVSSGFLGALVGGFIAGALVLAIKKYVKVPRSLEGAKSILLLPLLG
                     TILTGFVMLAVNIPMAAINTAMNDFLGGLGGGSAVLLGIVLGGMMAVDMGGPVNKAAY
                     VFGTGTLAATVSSGGSVAMAAVMAGGMVPPLAIFVATLLFKDKFTKEERNSGLTNIIM
                     GLSFITEGAIPFGAADPARAIPSFILGSAVAGGLVGLTGIKLMAPHGGIFVIALTSNA
                     LLYLVSVLVGAIVSGVVYGYLRKPQA"
     gene            29920..32172
                     /locus_tag="ACL3EZ_001257"
     CDS             29920..32172
                     /locus_tag="ACL3EZ_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HGR0392822.1"
                     /translation="MERKEAIQRMLISLGIAILLIFAAFKLGAAGITLYNLIRLLVGS
                     LAYLAIFGLLIYLFFFKWIRKQEGLLSGFFTIFAGLLLIFEAYLVWKYGLDKSVLKGT
                     MAQVVTDLTGFRTTSFAGGGLIGVALYIPTAFLFSNIGTYFIGSILILVGSLLVSPWS
                     VYDIAEFFSRGFAKWWEGHERRKEERFVKQEEKARQKAEKEARLEQEETEKALLDLPP
                     VDMETGEILTEEAVQNLPPIPEEKWVEPEIILPQAELKFPEQEDDSDDEDVQVDFSAK
                     EALEYKLPSLQLFAPDKPKDQSKEKKIVRENIKILEATFASFGIKVTVERAEIGPSVT
                     KYEVKPAVGVRVNRISNLSDDLALALAAKDVRIEAPIPGKSLIGIEVPNSDIATVSFR
                     ELWEQSQTKAENFLEIPLGKAVNGTARAFDLSKMPHLLVAGSTGSGKSVAVNGIIASI
                     LMKARPDQVKFMMVDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYEL
                     FAKVGVRNIAGFNAKVEEFNSQSEYKQIPLPFIVVIVDELADLMMVASKEVEDAIIRL
                     GQKARAAGIHMILATQRPSVDVISGLIKANVPSRVAFAVSSGTDSRTILDENGAEKLL
                     GRGDMLFKPIDENHPVRLQGSFISDDDVERIVNFIKAQADADYDESFDPGEVSENEGE
                     FSDGDAGGDPLFEEAKSLVIETQKASASMIQRRLSVGFNRATRLMEELEIAGVIGPAE
                     GTKPRKVLQQ"
     gene            complement(32325..32753)
                     /locus_tag="ACL3EZ_001258"
     CDS             complement(32325..32753)
                     /locus_tag="ACL3EZ_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6556 family protein"
                     /protein_id="HGR0392823.1"
                     /translation="MSNYRRTSKPKTEHIKKGFTVFQKTITTIGSILGLITAGITIMN
                     ALDNNNKNTKKEPTTSQTTTFVKEIQKESPQENTTPNKENNTSQEKTQQEETPKSSVK
                     EEKKEDQKTATQDSTTPATSKPATENEKQPNTPTSENNTQ"
     gene            32891..34033
                     /locus_tag="ACL3EZ_001259"
     CDS             32891..34033
                     /locus_tag="ACL3EZ_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase family protein"
                     /protein_id="HGR0392824.1"
                     /translation="MIYFDNSATTRPYPEALETYMQVASKILGNPSSLHRLGDQATRI
                     LDASRQQIADLIGKKSDEIFFTSGGTEGDNWIIKGVAFEKAQFGKHIIVSAIEHPAVK
                     ESALWLKAQGFEVDFAPVDNKGFVDVEALEDLIRPDTTLVSIMAVNNEIGSIQPIEAI
                     SEFLADKPTISFHVDAVQALAKIPTEKYLTERVDFATFSGHKFHGIRGVGFIYIKSGK
                     KITPLLTGGGQERDYRSTTENVAGIAATAKALRLSMEKLDIFRSKTGQMKAVIRQALL
                     DYPDIFVFSDEEDFAPHILTFGIKGVRGEVIVHAFEDYDIFISTTSACSSKAGKPAGT
                     LIAMGVDKDKAQSAVRLSLDLENDMSQVEQFLTKLKLIYNQTRKVR"
     gene            34042..35256
                     /gene="thiI"
                     /locus_tag="ACL3EZ_001260"
     CDS             34042..35256
                     /gene="thiI"
                     /locus_tag="ACL3EZ_001260"
                     /EC_number="2.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140741 - tRNA-uracil-4 sulfurtransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uracil 4-sulfurtransferase ThiI"
                     /protein_id="HGR0392825.1"
                     /translation="MQYSEIMIRYGELSTKGKNRMRFINKLRNNISDVLSIYPQVKVT
                     ADRDRAHAYLNGADYTAVAESLKQVFGIQNFSPVYKVEKSVEVLKSAVQEIMQDIYKE
                     GMTFKISSKRSDHTFELDSRELNQTLGGAVFEAIPNVQAQMKSPDINLQVEIREEAAY
                     LSYETVRGAGGLPVGTSGKGMLMLSGGIDSPVAGYLALKRGVDIEAVHFASPPYTSPG
                     ALKKAQDLTRKLTKFGGNIQFIEVPFTEIQEEIKAKAPEAYLMTLTRRFMMRITDRIR
                     EVRNGLVIINGESLGQVASQTLESMKAINAVTNTPIIRPVVTMDKLEIIDIAQEIDTF
                     DISIQPFEDCCTIFAPDRPKTNPKIKNAEQYEARMDVEGLVERAVAGIMITEITPQAE
                     KDEVDDLIDNLL"
     gene            35391..36215
                     /locus_tag="ACL3EZ_001261"
     CDS             35391..36215
                     /locus_tag="ACL3EZ_001261"
                     /inference="COORDINATES: protein motif:HMM:NF012958.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase-fold protein"
                     /protein_id="HGR0392826.1"
                     /translation="MNQSYFYLKMKEHKLKVPYTGKERRVRILLPKDYEKDTDRSYPV
                     VYFHDGQNVFNSKESFIGHSWKIIPAIKRNPDISRMIVVAIDNDGMGRMNEYAAWKFQ
                     ESPIPEQQFGGKGVEYAEFVMEVVKPFIKHKTGWFDGMMTTGCSMGAYHALNFFLQHP
                     DVFTKVIALSGVYDARFFVGDYYNDDAIYQNSPVDYIWNQNDGWFIDRYRQAEIVLCT
                     GLGAWEQDGLPSFYKLKEAFDQKQIPAWFAEWGHDVAHDWEWWRKQMLYFLGNLYL"
     gene            36228..37394
                     /locus_tag="ACL3EZ_001262"
     CDS             36228..37394
                     /locus_tag="ACL3EZ_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HGR0392827.1"
                     /translation="MNYLVISPYYPQNFQQFTIELANKGITVLGIGQESYEQLDEPLR
                     NSLTEYFRVDNLENIDEVKRAVAFLFYKHGPIDRIESHNEYWLELDATLREQFNVFGA
                     KPEDLKKTKYKSEMKKLFKKAGVPVVPGAVIKTEADVDQAVKEIGLPMIAKPDNGVGA
                     AATFKLETEDDINHFKQEWDHSTLYFFEKFVTSSEICTFDGLVDKDGKIVFSTTFDYA
                     YTPLDLMIYKMDNSYYVLKDMDPKLRKYGEAIVKEFGMKERFFHIEFFREGDDYITIE
                     YNNRPAGGFTIDVYNFAHSLDLYRGYAAIVAGEEFPASDFETQYCLATSRRANAHYVY
                     SEEDLLAKYSQQFKVKKVMPAAFAELQGDYLYMLTTPSRQEMDQMIADFGQRQE"
     gene            37902..39395
                     /locus_tag="ACL3EZ_001263"
     CDS             37902..39395
                     /locus_tag="ACL3EZ_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008170 - N-methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-6 DNA methylase"
                     /protein_id="HGR0392828.1"
                     /translation="MITGELKNKIDQLWEILWTEGNANPLTNIEQLTYLLFMKDLDSV
                     ELGRESDAEFLGIPYEGVFPKDKPEYRWSTFKNIGDAQEVYRLMTQEIFPFIKNLKGD
                     TDDTAFSRYMREAIFQINKPATLQKAISILDVFPTRGLDVDFDNDKQSITDIGDIYEY
                     LLSKLSTAGKNGQFRTPRHIIDMMVELMQPTIKDIISDPAMGSAGFLVSASRYLKRKK
                     DEWETNTDNINHFHNQMFHGNDTDTTMLRLGAMNMMLHGVENPQISYLDSLSQDNEEA
                     DKYTLVLANPPFKGSLDYNSTSNDLLATVKTKKTELLFLSLFLRTLKPGGRAAVIVPD
                     GVLFGSSKAHKGIRQEIVENHKLDAVISMPSGVFKPYAGVSTAILIFTKTGNGGTDKV
                     WFYDMKADGLSLDDKRQPISDNDIPDIIERFHHLEKEAERQRTDQSFFVPVAEIKEND
                     YDLSINKYKEIEYEKVEYEPTEVILKKINDLEKEIQAGLAELEKLLK"
     gene            39408..40331
                     /locus_tag="ACL3EZ_001264"
     CDS             39408..40331
                     /locus_tag="ACL3EZ_001264"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HGR0392829.1"
                     /translation="MKKVKLGEVLSLKKGKKATVLAEQTTLSQRYIQIDDLRNNNNLK
                     FTESLNMTEALPDDILIAWDGANAGTVGYGLSGAVGSTITVLKKNERYKEKIISDYLG
                     VFLESKSQYLREHSTGATIPHLNKNILLDLQLELLGIEEQENIICILNTIKGLITKRK
                     LQLDELNLLVKSRFNEMFGENKIFESIDNLFDIIDGDRGKNYPKSDELFSEEYCLFLN
                     TKNVTKNGFSFDTKQFITKTKDKLLRKGKLERYDIVLTTRGTVGNVAYYDELIKYKHL
                     RINSGMVILRPKTPNLNHNWQSKNLWKNLKL"
     gene            40423..40659
                     /locus_tag="ACL3EZ_001265"
     CDS             40423..40659
                     /locus_tag="ACL3EZ_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000260605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HGR0392830.1"
                     /translation="MVVKTRKQGNSITITIPSEFNIPSGVKYEAKLLPSGEIIFTPEE
                     LGQQVSYVSDDAFDLNLDKIFDEYDDVFKALVEK"
     gene            40656..41069
                     /locus_tag="ACL3EZ_001266"
     CDS             40656..41069
                     /locus_tag="ACL3EZ_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000158364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HGR0392831.1"
                     /translation="MTIYLTEKQIEKINALAIQRYSPNEKIQTVSSSALNMIVNLPEQ
                     FVFGKSLYPTIFDKATILFVQLIKKHVFANANKRTAFFVLVKFLQLNGYRFSVTVEEA
                     VKMCVTIAVEALTDEKMTSYSKWVSEHSVREKVKK"
     gene            41187..42152
                     /gene="xerA"
                     /locus_tag="ACL3EZ_001267"
     CDS             41187..42152
                     /gene="xerA"
                     /locus_tag="ACL3EZ_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008907 - integrase activity [Evidence
                     IEA];
                     GO_function: GO:0009037 - tyrosine-based site-specific
                     recombinase activity [Evidence IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase/integron
                     integrase"
                     /protein_id="HGR0392832.1"
                     /translation="MESKVTIIMQEMLPLLNNEQLLALRESLEHHLVDGKKQQKYSNN
                     NLLQLFITAKQVEGCSSKTIRYYQRTIENLFNAIKESVTQLTTDDLRSYLANYQSEKD
                     CSKANLDNIRRILSSFFAWLEQEEYIIKNPIRRIKKIKTEQNVKETYTDEHLEIMRDN
                     CENLRDLAIIDLLASTGMRVGELVQLNRSDIDFENRECVVFGKGKKERPVYFDARTKI
                     HLRNYLNDRKDSHPALFVTLVGKAQRLGIAGVEIRLRKLGDKLGIQKVHPHKFRRTLA
                     TKAIDKGMPIEQVQKLLGHSKIDTTLAYAMVNQNNVKHSHQKFIS"
BASE COUNT        12949 a         7549 c         9242 g        12423 t
ORIGIN      
        1 caagagggag agtacctaaa atgggacgta agccaaaaac gagacctgaa gagaggacag
       61 aattagaacg tcttcaagca gaaaatgagt acctgagagc ggagaatgcc atcctaaaaa
      121 agttaagaga actccgattg aaggaggaaa aagagaaaga agaaagacag aaattgttca
      181 agaattaatg actgagtttt cgttagctct tcttctaaaa gccattaaac tagctcgttg
      241 gacctactac tatcacttga aacagctaga taaaccagat aaggaccaag agcttaaagc
      301 tgaaattcaa tccatcttta tcgaacacaa gggaaattat ggttatcgtc gaatttattt
      361 agaactaaga aatcgtggtt atctggtaaa tcataaaaga gttcaaggct tgatgaaagt
      421 actcaattta caagctaaaa tgcgacagaa acgaaaatat tcttctcata aaggagacgt
      481 tggtaagaaa gcagagaatc tcattcaagg ccaatttgaa ggctctaaaa caatggaaaa
      541 gtgctacaca gatgtgacag aatttgccat tccagcaagt actcaaaagc tttacttatc
      601 accagtttta gatggcttta acagtgaaat tatcgcctat aatctttcaa tttcacccaa
      661 cttagaacaa gtacaaacaa tgttggaaca agccttcaca gagaagcact acgagaatac
      721 gattctccat agtgaccaag gctggcaata tcaacacgat tcttatcatc agtttcttga
      781 gggtaaggga attcaagcat ccatgtcacg caagggaaac agccaagaca acggtatgat
      841 ggagttcttc tttgggattc tgaaatcgga aatgttttat ggctatgaga aaacatttaa
      901 atcacttaat caattggaac aagctattgt agactatatt gattactaca acaataaacg
      961 aattaaggta aaactaaaag gacttagcct tgtgcaatac agaactaaat ccttcggata
     1021 aattaattgt ctaacttttg gggggcagta cagaactggc attttatttt ttaggatctt
     1081 gatgggttag gttcaatccc caagggacca aattttcagt tttatttttg atacgagcta
     1141 tattgtcctt atgacgaatg ataatcaaac tagcaagtgc taagataata gcgatgaaga
     1201 gagagtcata gttactcagg ataaaaccaa aaagtggaaa gagcagaacc ccgataacag
     1261 ccgcgatcga tgctgtgaca ctagacagtg aaatcatact gccaagatag agagctccaa
     1321 agaagataat cgcaaggtag agacagaaga taggcgcaaa tccgaaaatc actccagcac
     1381 tggttgcgac agccttacca cctttaaatc ctgcaaagat agggaaggta tggccgataa
     1441 cagccaaaag tccaaagatg agaggagaaa cgccttgtag atgaaaaata atcggaagca
     1501 gcgttgctag ggttcctttg aaaaagtcaa tcacaaaggt tgccatacca gctttcttac
     1561 ctaaaatgcg gaaggtgttg gtcgttccag tgttaccaga accatgctcg cgtagattga
     1621 tttgaaagaa tacttgtcca atccagagac cagatggaat cgaacccagc agataggcta
     1681 ggattaataa aactattgta atcatactcc tattatatca tgaattggga aagaaaagca
     1741 gagaatctct gctgaaattg tcacatcgga gaaagaaaaa ttttgcaaaa tccttggaaa
     1801 acctgtagaa tagtaaagat gaacgaatag gaggttcctt gtgtcaaaaa aggaaatcaa
     1861 tattaacaat tataatgatg atgctattca ggtgctagaa gggttggatg cggtccgaaa
     1921 acgtccaggg atgtatattg gatcgaccga tggcgctggt cttcatcacc tagtttggga
     1981 aatcgttgat aatgcagtcg atgaagcctt gtctgggttt ggtgatcgta ttgatgtaac
     2041 tatcaataaa gacggtagtc taacggttca agaccatgga cgtgggatgc cgacaggtat
     2101 gcacgctatg ggaattccaa ctgttgaggt tatctttacc attcttcatg ccggagggaa
     2161 attcggtcaa ggtggctata agacatcagg tggacttcac ggagtgggtt cttccgttgt
     2221 taacgccctt tctagctggt tagaagttga aattacccgt gatggcgcag tttacaagca
     2281 acgttttgaa aatggtggaa aacctgtcac gactttgaag aaaatcggta cagcactcaa
     2341 gtctaaaaca ggcaccaaag ttacttttat gcctgacgcg actatctttt ctacgacaga
     2401 tttcaagtac aataccattt cagagcgcct taatgaatca gcctttctct tgaaaaatgt
     2461 gaccttgtct ttaacggaca agcgaacaga tgaagcgatt gagttccact atgagaatgg
     2521 agtacaagat tttgtttctt atctcaacga agataaggaa atcttgacgc cagttcttta
     2581 ctttgaaggg gaagacaatg gttttcaagt ggaagtagcc ctccagtaca atgacggatt
     2641 ctcagataac attctatcct ttgtcaataa cgttcgcacc aaggacggtg gaacgcacga
     2701 gacaggactc aagtctgcca ttaccaaggt catgaatgac tatgcacgta aaacaggtct
     2761 tctcaaggaa aaagataaaa accttgaagg ttcagactat cgtgagggac tagcggccgt
     2821 tctttctatc ttagttcctg aagaacactt gcagtttgaa ggacagacca aagataaact
     2881 aggaagcccc ctagctcgcc cagttgtgga tggaatagtg gctgataagt tgaccttttt
     2941 ccttatggaa aatggggaat tagcttctaa cctcatccgc aaggctatca aggcccgtga
     3001 tgctcgtgaa gcagcacgta aggcgcgtga tgagagccga aatgggaaga aaaacaagaa
     3061 agataagggc ttgttgtctg ggaaattgac cccagcccaa tctaagaatc ctgctaagaa
     3121 tgaactctat ctagttgagg gggactctgc cggtggttct gccaaacaag gtcgtgaccg
     3181 caagttccag gctattctac ctcttcgtgg taaggttgtc aatacagcca aggccaagat
     3241 ggcggatatc ctcaaaaatg aagagatcaa taccatgatt tataccattg gtgcgggtgt
     3301 tggagcagac ttctctattg aagatgccaa ctatgataag atcattatca tgaccgatgc
     3361 ggataccgac ggtgcccata tccagacctt gctcttgaca tttttctacc gttacatgcg
     3421 tccgctagtc gaggcaggtc atgtctatat tgccctccca cctctttaca agatgtccaa
     3481 aggtaaaggc aagaaagaag aagtggccta cgcttggacg gacggagaac tagaagaact
     3541 ccgtaaacag ttcggtaaag gcgctaccct ccaacgatac aaaggacttg gtgagatgaa
     3601 tgcggaccag ctctgggaaa caaccatgaa cccagaaaca cgtaccctca tccgtgtcac
     3661 aattgaagat ttagcgcgcg ccgaacgccg cgtcaatgtt ctcatgggag ataaggtaga
     3721 accacgccgt aaatggattg aagataatgt caagtttacg ctagaagaag cgacagtgtt
     3781 ttaatgaaag aaaataatat gttagtaaac tggaaattag agtcggatgt gaatgactat
     3841 gtaaaaaagc agtttgaaaa tcttggtttg aaaaaattgc aggattatta atgaagaatc
     3901 ttctatgagt gcttatctca aagaggcgtt taagggagcg gctaagacac aaactaagac
     3961 taattttgga aaaccagatt ttcatattga aaaatacaaa caggatagtt tggttactta
     4021 tcgtaactga acacgggacg aattcccgta aaatatcttt tactgcataa aaacctactc
     4081 tacattcttt gaaaggagtt gaacacgccc tagatactgt gtgaaaaaga taaattctct
     4141 tgtgagtttg cttacttcaa gaattttcta ttttcacttg gtattttatg ggctttgtat
     4201 cttatgtcta acattcaaaa tatgtccctg gaggacatca tgggagagcg ctttggtcgc
     4261 tactccaagt acattattca agaccgggct ttgccagata ttcgtgatgg gttgaagccg
     4321 gttcagcgcc gtattcttta ttctatgaat aaggatagca atacttttga caagagctac
     4381 cgtaagtcgg ccaagtcagt cgggaacatc atggggaatt tccacccaca cggggattct
     4441 tctatctatg atgccatggt tcgtatgtca cagaactgga aaaatcgtga gattctagtt
     4501 gaaatgcacg gtaataacgg ttctatggac ggagatcctc ctgcggctat gcgttatact
     4561 gaggcacgtt tgtctgaaat tgcaggctac cttcttcagg atatcgagaa aaagacagtt
     4621 ccttttgcat ggaactttga cgatacggag aaagaaccaa cggtcttgcc agcagccttt
     4681 ccaaacctct tggtcaatgg ttcgactggg atttcggctg gttatgccac agacattcct
     4741 ccccataatt tagctgaggt catagatgct gcagtttaca tgattgacca cccaactgca
     4801 aagattgata aactcatgga attcttgcct ggaccagact tccctacagg ggctattatt
     4861 cagggtcgtg atgaaatcaa gaaagcttat gagactggga aagggcgcgt ggttgttcgt
     4921 tccaagactg aaattgaaaa gctaaaaggt ggtaaggaac aaatcgttat tactgagatt
     4981 ccttatgaaa tcaataaggc caatctagtc aagaaaatcg atgatgttcg tgttaataac
     5041 aaggtagctg ggattgctga ggttcgtgat gagtctgacc gtgatggtct tcgtatcgct
     5101 atcgaactta agaaagacgc taatactgag cttgttctca actacttatt taagtacacc
     5161 gacctacaaa tcaactacaa ctttaatatg gtggcgattg acaatttcac acctcgtcag
     5221 gttgggattg ttccaatcct gtctagctat atcgctcacc gtcgagaagt gattttggcg
     5281 cgttcacgct ttgacaaaga aaaggctgag aaacgtctcc atatcgtcga aggtttgatt
     5341 cgtgtgattt cgattttgga tgaagtcatt gctcttatcc gtacttctga gaataaggcg
     5401 gacgccaagg aaaacctcaa agttagctat gactttacgg aagaacaggc tgaggctatc
     5461 gtaactttgc aactgtaccg tttgaccaat accgatgtgg ttgtcttgca ggaagaagaa
     5521 gcagagcttc gtgagaagat tgctatgctg gcggctatta tcggtgatga aaggactatg
     5581 tacaatctca tgaagaaaga acttcgtgag gtcaagaaga aatttgcaac tcctcgtttg
     5641 agttctttag aagacactgc gaaagcaatt gagattgata cagctagtct tatcgctgag
     5701 gaagatacct acgtcagcgt gaccaaggca ggttacatca agcgtaccag tccacgttcc
     5761 tttgcggctt ccaccttgga agaaattggc aagcgtgatg atgaccgttt gatttttgtt
     5821 caatctgcca agacaaccca gcacctcttg atgttcacaa gtcttggaaa tgtcatctac
     5881 agaccaatcc atgagttggc agatattcgt tggaaggaca tcggagagca tctgagccaa
     5941 accatcacaa actttgaaac gaatgaagaa atcctttatg tggaagtact ggatcagttt
     6001 gacgatgcga caacctactt tgcagtgact cgccttggtc aaatcaaacg ggtagagcga
     6061 aaagaattca ctccatggcg gacctataga tctaagtctg tcaagtatgc taagctcaaa
     6121 gacgatacag atcagattgt agcagtggct ccgattaaac tagatgatgt tgtcttggtt
     6181 agtcaaaatg gttatgccct gcgtttcaat atcgaagagg ttccggttgt cggtgctaag
     6241 gcagcaggtg tcaaggctat gaatttgaaa gaagatgatg tcctccaatc tggctttatc
     6301 tgtaatactt cgtccttcta cctcttgacc cagcgtggaa gcttgaaacg tgtttccatt
     6361 gaggaaattc tagcaaccag ccgtgccaaa cgaggattac aagtcttgcg tgagttgaaa
     6421 aacaaaccgc atcgtgtctt cttggcagga gcagttgcag agcaaggatt tgttggcgat
     6481 ttcttcagta cggaagtgga tgtgaacgac caaactctgc ttgtccaatc caataaagga
     6541 acaatctatg aaagccgatt gcaagacttg aacttgtcag aacgcactag caatggaagc
     6601 ttcatttctg acacgatttc agatgaagaa gtttttgacg cttatcttca ggaagtagtt
     6661 actgaagata aataagtgaa atgaagaatc agttctaaga gctggttttt attggagaaa
     6721 ttttctgaaa attacaaaat atacttgcta ttttagaaaa atagtgtaga atataagaaa
     6781 taggttttta gaataaggag tggaatatga cagtaacgat tgattgggaa aacctcggtt
     6841 tttcctatat gaaattacct tatcgctatc ttgctcattt caaaaatgga caatgggatc
     6901 aaggagagct tacagaggat gcaactttgc atatttcaga gtcttctcca agtcttcact
     6961 atggacaaca agcatttgaa ggtttgaaag cttatcgtac taaggatggc agtgttcaac
     7021 tgttccgtcc tgatgaaaat gctaaacgtc tgcaacgtac atgtgaccgt ctcttgatgc
     7081 cacaagttcc gacagacatg tttgtagaag cttgtaaagc agttgtccgt gcgaatgaag
     7141 aatacgtacc accatacgga acaggtggaa ccttatatct tcgccctctt ttgattggtg
     7201 tcggagatat tatcggggta aaaccggcag aagagtacat tttcaccatc tttgctatgc
     7261 cagttggaaa ttactttaaa ggtggtttgg tcccaaccaa cttcttgatt caggatgagt
     7321 acgaccgtgc agcaccaaat ggtacaggtg cggctaaggt tggtggaaac tatgctgcaa
     7381 gtctcttacc aggaaaaatg gccaagtcac gtcatttctc agatgttatc tatctggacc
     7441 catcaactca tacaaagatt gaagaagtcg gatcagctaa cttctttgga attacagctg
     7501 ataatgaatt tgtaacacca ttgagtccat ctatcttgcc atctattacc aagtattcct
     7561 tgctttattt ggcagaacat cgcttgggat taactcctat tgagggtgat gttccaattg
     7621 ataatcttga ccgttttgta gaggcaggtg cctgtggtac agcagcggtt atttctccaa
     7681 ttggaggtat tcaacatggt gatgatttcc atgtattcta tagtgaaaca gaagtaggtc
     7741 ctgtgacgcg taaattatat aatgaattga cgggtattca gtttggcgat attgaagcgc
     7801 cagaaggttg gattgtaaaa gtagattaaa ataaaccaaa ggagattttt tatgaaatag
     7861 aaaaagtggc tcttaacagc aggagtggtc ctgagcacgt cagctatttt agtggcttgt
     7921 ggaaaaactg ataaagaagc agatgcaccg acaacatttt cttatgtcta tgcagtagat
     7981 ccagcatcat tgggctacag tatagcgact cgaacatcga ggacagacgt tattggaaat
     8041 gttattgatg gtttgatgga aaatgataaa tacggcaatg ttgctccttc tcaaaaagac
     8101 tatgatttga atagtacagg atgggctcca agctatcaag atccagcgtc ttacttgaat
     8161 attatggatc caaaatctgg ttctgccatg aaacaccttg gtattacgaa aggaaaagat
     8221 aaggatgttg tagctaaacc tggtttggat aaatataaga aattgttaga agatgctgtt
     8281 tctgagacca ctgacctaga gaagagatat gaaaaatatg ccaaagctca agcttggtcg
     8341 acagatagtt cattattgat gccaacagct tcatctggtg gttctccagt tgtaagtaac
     8401 gtagtaccat tctcaaaacc atactcacaa gttggtatta agggggaacc atatatcttt
     8461 aaaggaatga aattgcaaaa agatattgtt acaacaaaag aatataacga ggtttttaaa
     8521 aaatggcaaa aagaaaaatt ggaatccaat agcaaatacc aaaaagaact agaaaaatac
     8581 attaaataag gaatggtatt gatcttgata aaatttttaa aatactgtca ttttgaatat
     8641 aaaggagttt gatatggagt ggattagatt aataggaata gcaatcattg ttgtgggttt
     8701 tattttaaaa tttgatacaa ttgcaacagt agtcttagct ggtttggtta cagctttagt
     8761 ttcaggtgtt tctctcgttg aatttttgga gattttggga aaagaattta gcaatcagcg
     8821 agtgctcacg atttttatgg ttaccttgcc tcttgtgggg ctgtcagaaa cctttggact
     8881 caagcaacga tcaatcgatt tgattcgaaa gattaaaggt ctgacagttg gaaacttcta
     8941 tacagtttat ttttttattc gagagttagc tggtttcttt tcaattcgtc taggaggaca
     9001 ccctcagttt gtcagacctt tggttcaacc tatgggagaa gcagctgcag agtctcaatt
     9061 aggtagaaag ttaacagagg ttgaagatga gacaataaaa gcgcgtgcgg ctgcgaatga
     9121 aaattttgga aatttctttg ctcaaaatac gtttgtaggt gctgggggag tcctcttgat
     9181 agggggaaca ttagatcagt taggctatga aagcaattat gcagggattg cttctacatc
     9241 tattattgtt gctgttataa cacttattgt agtggggatt tacaattatt tatttgataa
     9301 aaaattgata tcaaaaaaga ctaggggagg agaacaaaaa tgacagagtt ggcaaagcaa
     9361 ctattagagt tgacctatat tgtgattggt tgtcaatttc tccatacagc ctattgtagt
     9421 tataaagata aaacaaaccc agttcgactt gggacatctg cattttggac tctattgtct
     9481 attacgttta taggtggttc ctatatgcca aatatgagta ttggtattat tgtaatccta
     9541 ttatcgctgt taacattgtt taagcaagtc cgtatcggaa ccttgccatc cttagatgaa
     9601 atgaaagcca atattgaatc taacaggttg aaaaataaaa tttttattcc agttatgctg
     9661 atggcaatac ttgcgttggt cttagcgcaa atgattccag aatttagcaa gatttcgatt
     9721 agccttgccg ccttgtttgc tacaatttct gttcttgtga ttaccaatag tcaccctaag
     9781 agtctgttat cagaaaataa tcgaatgact cagcaagttt caacaagtgg tattgttcct
     9841 caattattag gggctttggg ggctattttt actgtagcag gtgttggtga tgttatctct
     9901 catctgatta gcggtattgt tccttcagat agtcgcttta taggagtttt ggcctatgtt
     9961 cttggaatgg ttctattcac aatgattatg ggaaatgctt ttgcagcatt caccgttatt
    10021 acagcaggtg ttggagttcc ctttgtattt gctctgggag ctaatccaat tgtggctggt
    10081 gctcttgcca tgacagcagg ttattgtggg accttattga ccccaatggc tgctaatttt
    10141 aacgctctac cagcagcatt gatggatatg aaagatcaga atggcgttat aaaggctcaa
    10201 gcaggtgttg ctctagtaat gattgttatt cacatattct taatgtactt tctcgcattt
    10261 tagtaaagga aaataaaatg aaaatattgg ttacaggttt taatcctttt ggaggtgaaa
    10321 agattaatcc agctttggag gctgtaaaat tattaccatc tgagattaat ggggctgaag
    10381 ttcgctgggt agaaattcca acggtttttt ataagtcgtc agaagtttta gaggcagaaa
    10441 tattacgata tcaaccagat gctgtacttt gtattggaca agcaggcggc aggaccggct
    10501 taacacctga acgagtggct attaatcaag atgatgctcg catacctgat aacgaaggca
    10561 atcaaccaat tgatacaccg attcgtattg atggagcatc ggcctatttt agtagtttac
    10621 ctatcaaagc gatggtacaa gctatcaaaa aacagggact tccggcagtt gtatccaata
    10681 gtgcaggaac ctttgtttgc aatcatttga tgtaccaagc tctttattta gtggataaaa
    10741 aattccctaa tatgagagca ggtttcatgc atattccata tatgatggaa caagtagtaa
    10801 ataagccgaa tactgcagga atgagtctat gtgatattgt aagaggcata gaggtagcta
    10861 ttgaagctat tgtagactac aaagataagg atttgcagtt agtaggcggt gagactcact
    10921 gataacctaa aaaggatagt caattatgct tgtttactaa ctattagcta tgctaaatcg
    10981 attgaggttg tttacataaa actctatatc agagaagcct gatatagagt tttttcttgc
    11041 tagttttagg attttcttgt aaaatagaaa aagtgaagag aggtatgaaa tgagcaagaa
    11101 agataaaaaa atcgaaattc aagtagcgga tgccaaagtt aatgttggta aagacagttt
    11161 tgaaggttat acattgacta tcggtaaaaa agttatcgga gaaattgccg aattagacgg
    11221 acaatttgcc attataaaga atgggaatgt cgatagtttt tataaaaaat tggaaaaagc
    11281 tgtggaaatt ttgattgaaa attataattt agcaaaataa gtcttgtttt tttgaaattt
    11341 tcatgatata atagtccatg ttgattgtag gagagatagc gaagaggcta aacgcggcgg
    11401 actgtaaatc cgctccttcg ggttcggggg ttcgaatccc tctctctcca tttcattaat
    11461 ggggtatagc caagcggtaa ggcaagggac tttgactccc tcatgcgttg gttcgaatcc
    11521 agctacccca gttcttaggt aataatcaag ataaaaagca aaatatctta gggtatttta
    11581 tttttataat tgaaagacgt gaatgatatg aacatgtcct tgcgggtgct taggaaaaaa
    11641 attataagta tgtcaagttt aagaaaaact tgattgttgg aggatttttt agatgaacga
    11701 atttgaagat ttgctaaata gcgttagtca agttgagact ggtgatgttg ttagtgctga
    11761 agtattgaca gttgatgcga ctcaagctaa cgttgcaatc tctggaactg gtgttgaagg
    11821 tgtcttgact cttcgcgaat tgacaaacga tcgtgatgca gatatcaatg actttgttaa
    11881 agtaggagaa gtattggatg ttcttgtact tcgtcaagta gttggtaaag atactgatac
    11941 agttacatac cttgtatcta aaaaacgcct tgaagctcgc aaagcatggg acaaacttgt
    12001 tggtcgcgaa gaagaagttg ttactgttaa aggaacgcgt gccgttaaag gtggactttc
    12061 agtagaattt gaaggtgttc gtggatttat cccagcttca atgttggata ctcgtttcgt
    12121 acgtaacgct gagcgttttg taggtcaaga atttgatact aaaatcaaag aagttaacgc
    12181 taaagaaaac cgcttcatcc tttcacgtcg tgaagttgtt gaagcagcta ctgcagcagc
    12241 tcgcgctgaa gtattcggta aattggctgt tggtgatgtt gtaactggta aagttgctcg
    12301 tatcacaagc ttcggcgctt tcatcgacct tggtggtgtt gacggattgg ttcacttgac
    12361 tgaattgtca catgaacgta acgtatcacc aaaatcagtt gtaactgttg gtgaagaaat
    12421 tgaagtgaaa atccttgatc ttaacgaaga agaaggacgt gtatcacttt cacttaaagc
    12481 aacagtacca ggaccatggg atggcgttga gcaaaaattg gctaaaggtg atgtagtaga
    12541 aggaacagtt aaacgtttga ctgacttcgg tgcatttgtt gaagtattgc caggtatcga
    12601 tggacttgtt cacgtatcac aaatttcaca caaacggatt gaaaatccaa aagaagctct
    12661 taaagttggt caagaagttc aagttaaagt tcttgaagtt aacgcagatg cagaacgcgt
    12721 atcactttct attaaagctc ttgaagaacg tccagcccaa gaagaaggac aaaaagaaga
    12781 aaaacgtgct gctcgtccac gtcgtccaag acgtcaagaa aggcgtgatt tcgaacttcc
    12841 agaaacacaa acaggatttt caatggctga tttgtttggt gatatcgaac tttaatcaaa
    12901 ttgaaaattc acaaaatcct ttgtttacta aacaagggat ttttctggct ctttgtcaac
    12961 tgtagtgggt tgaagtcagc taaggttgag aaaggacaaa tttcgtcctt tcttttttga
    13021 tgttcagagc gataaaaatc cgttttttga agttttcaaa gttccgaaaa ccaaaggcat
    13081 tgcgtttgat aagtttgatg agattattgg tcgcttccaa tttggcgttt gaatagggta
    13141 gttgaagggc gttgacgatt ttctctttgt tctttagaaa ggttttaaag acagtctgaa
    13201 aaagaggatg aacctgctta agattgtcct caataagtcc gaaaaatttc tctggttcct
    13261 tattatagag ctgatagtgg tgtttcaagt cttctgaata gctcaaaagc ttgtttaaaa
    13321 tctctttatt ggttaagtac atacgaaaag taggacgata aaatcgctta ttactcagtt
    13381 tacggctatc ctgttgaatg agtttccagt agcgcttgat agccttgtat tcatgagact
    13441 ttcgatgaaa ctgattcatg atttggacat gcacacgact catagcacgg ctaagatgtt
    13501 gtacaatatg aaagcgatca agaacgattt tagcattcgg gagtgaaaca gtctgggaga
    13561 ctgtttcagc ctgagcctag aaatttgaaa gcgaagttgt ctagctaagt catagtaagg
    13621 actaaacata tccatagtaa tgattttcac ttgacaacga acggctctat catatttaag
    13681 aaagtgatct cggatgatag cttgtgttct accttcaaga acagtgatga tattgagctt
    13741 ttcaaaatct tgcgcaataa agctcatctc catctcccga ttgaaacagt cactccccgg
    13801 actgtttcaa cgtcccaaga cataatctca ggcagatttc taaaattaca ctcaaagtgg
    13861 aagtcattga gctttcgaat gacagttgaa gttgagatgg aaagctgatg ggcaatatcg
    13921 gtcatagaaa tcttttcaat taacttttga gcaatctttt ggttgatgat acgagggatt
    13981 tggtgattct tcttgacgat agaagtttca gcgaccatca tttttgaaca gtgatagcac
    14041 ttgaatcgac gctttctaag gagaattcta gtaggcatac cagtcgtttc aaggtaagga
    14101 attttagacg gtttttgaaa gtcatgtttc ttcatttgac ttccgcactc agggcaagat
    14161 ggggtgtcat aatccagtct agcgatgatt tccttgtgtg tatccttatt gatgatgtct
    14221 aaaatctgga tattagggtc tttaatgtct agtaattttg tgataaaatg taattgttct
    14281 atatgattct ttctaatgag ttgttttgtt gcttttcatt ataggtcata tgggactttt
    14341 tttctacaca aaataggctc cataatatcc ataggggatt tacccactac aaatattata
    14401 gagcccaaaa tcctttgttt actaaacaag ggatttttct tttgtctctg ctcctttttt
    14461 gatataatag ttctatgtta aaatcagaaa aacaatcacg ttatcaaatg ttaaatgaag
    14521 aattgtcctt cctattggaa ggcgaaacca atgttttggc taatctttcc aacgccagtg
    14581 ctctcataaa atcacgtttt cctaataccg tatttgcagg cttttatttg ttcgatggaa
    14641 aggaattggt tttaggcccc ttccaaggag gtgtttcctg catccgtatt gcactaggca
    14701 agggtgtttg tggtgaggca gctcactttc aggaaactgt tattgttgga gatgtgacga
    14761 cctatctcaa ctatatttct tgtgatagtc tagctaaaag tgaaattgtg gtgccgatga
    14821 tgaagaatgg tcagttactt ggagttctgg atctggattc ttcagagatt gaggattacg
    14881 atgctatgga tcgagattat ttggaacaat ttgtcgctat tttgcttgaa aagacaacat
    14941 gggactttac gatgtttgag gaaaaatctt aatgtatcaa gcactttatc gaaaatatag
    15001 aagtcaaaac ttctcccagt tagttggtca agaagttgtg gctaagactc ttaaacaagc
    15061 ggtggagcaa gagaaaataa gtcacgctta tcttttttct ggtcctcgtg gaacgggaaa
    15121 aaccagtgtt gctaaaatct ttgccaaggc tatgaactgt cccaatcaag tgggtggcga
    15181 accttgcaat aactgctata tttgtcaagc agtgacggac ggtagtttag aagatgtcat
    15241 tgaaatggat gcagcttcta ataatggggt agatgaaatt cgcgaaattc gtgataaatc
    15301 tacctatgcg cctagccttg ctcgttataa ggtttatatc atagatgagg ttcacatgct
    15361 gtctacaggg gcttttaatg ccctcctaaa gacgctggaa gaaccaacac agaatgtagt
    15421 ctttattttg gccactactg aattgcacaa gattcctgct actattctat cccgtgtgca
    15481 acgttttgag tttaaatcaa ttaagacaca ggatattaag gaacatattc actatatctt
    15541 agaaaaagaa aatatcagtt ctgaaccaga ggctgtggaa atcattgcca ggcgggcgga
    15601 aggtggaatg cgggacgcct tgtctatttt ggatcaagcc ctgagtttga cacagggaaa
    15661 tgagctgacg actgctatct ctgaagaaat tactggcacc attagcctat cagccttgga
    15721 tgattatgtg gcggccttgt ctcaacagga tgttcccaaa gctttgtctt gcttgaatct
    15781 tctttttgac aatggtaaga gcatgactcg ttttgtgacc gatcttttgc actatttaag
    15841 agacttgtta attgttcaaa cagggggaga aaatactcat catagttcag tctttgtaga
    15901 aaatttggca cttcctcaaa aaaatctgtt tgaaatgatt cgcttagcaa cagtgagttt
    15961 agcagatatt aagtctagtt tgcagcccaa gatttatgct gaaatgatga ccgtccgttt
    16021 ggcggaaatc aagcccgaac cagctctatc aggagcggtt gaaaatgaaa ttgctacgct
    16081 gagacaggaa gttgcccgtc tcaaacaaga gctttctaat gtaggtgcgg ttcctaaaca
    16141 agttgcacca gctcctagtc gaccagctac gggcaaaaca gtctatcgtg tcgatcgcaa
    16201 taaagtgcaa tctatcttac aagaggccgt cgaaaatcct gatttagcac gtcaaaatct
    16261 aattcgtttg cagaatgcct ggggagaggt aattgaaagt ctaggtgggc cggacaaggc
    16321 tctgctagtt ggttctcaac cggttgctgc caatgaacac catgctattc ttgcttttga
    16381 gtctaacttc aatgctggtc aaactatgaa acgagacaat ctcaatacca tgtttggtaa
    16441 tatcctcagt caggcggcag gtttttcacc tgagatttta gctatttcca tggaggaatg
    16501 gaaagaagtt cgcgcagcct tttcagccaa agccaaatct tctcaaactg aaaaagaagt
    16561 agaagaaagc ctgattccag aaggatttga atttttggct gataaagtga aggtagagga
    16621 agactaaaga aagatttcat gatacaataa gtttatgaat aaacaacaat ttattattat
    16681 ggcgctgttt acagctgctg agacctattt tttcaatgaa gcctggatga ctggccgcta
    16741 tattatggca gccttttggg caattttact ctttagaaat ttccgagtca gttatgtgat
    16801 gggcaaaatc gttgatgtca tcgatcagca ttttaatagg aaagactagc cctcagcttc
    16861 cagacaaaat caaagccttt taggcttttt tttgttatac tagaaaagta tatttataga
    16921 atttttgctc tatttctggg gaaatcagac gtttttctag taagtactgt aaaagttttg
    16981 aaaaagaaag gaactatcat gtcagtatta gagatcaaag atcttcacgt tgagattgaa
    17041 ggaaaagaaa ttttaaaagg ggttaacctg accctgaaaa caggagaaat tgccgctatc
    17101 atgggaccaa atggtacagg taaatcgact ctttctgccg ctatcatggg aaatccaaac
    17161 tatgaagtaa ctaaaggtga agttttgttt gatggcgtaa acatccttga gttggaagtg
    17221 gatgagcgtg cgcgtatggg acttttcctt gctatgcaat acccatcaga aatccctgga
    17281 attaccaatg ctgagtttct tcgtgccgct atgaatgcgg gtaaagaaga tgatgagaag
    17341 atttcagttc gtgagtttat tactaagcta gatgaaaaaa tggaattgct taacatgaaa
    17401 gaagaaatgg cagagcgtta cctcaacgaa ggcttctctg gtggtgagaa aaaacgcaat
    17461 gaaattcttc aacttttgat gttggagcca acatttgctc ttttggacga gattgactca
    17521 ggtcttgata ttgacgctct taaagttgtg tctaaaggtg tcaatgccat gcgtggtgaa
    17581 ggttttggtg ctatgatcat tactcactac caacgtcttt tgaactatat cacacctgat
    17641 gtggtacacg tgatgatgga aggtcgtgtt gtcctttctg gtggtccaga attggctgcg
    17701 cgtttggaac gtgaaggata cgcaaaatta gctgaagaac ttggctacga ctacaaggaa
    17761 gaattgtaat tccctcgtat cttttaggag aagtaaatga ctagagaaaa tattaaactt
    17821 ttttcagaaa tgcacgctga accaagctgg ttggctgatc tccgtcaaaa agcttttgac
    17881 aagattgaga ctttggaatt accagttatt gagcgtgtca aattccaccg ttggaatctg
    17941 ggtgatggaa cgattacaga aaatgagcca tcagcaaatg ttccagattt cacagcttta
    18001 gatcatcact tgaagttggt gcaagtagga actcaaactg ttttcgaaca aactccagtt
    18061 gagttagctg aacagggtgt tgtcttcaca gactttcact cagctttaga agaaattcca
    18121 gagctgatcg aagaattctt catgtcatct gttaagtatg atgatgacaa gttggcggct
    18181 taccacacag cttactttaa cagtggtgct gtactctata ttccagataa tgtagaaatc
    18241 acagagccaa ttgaaggaat tttctaccaa gatagcgata gcaatgtgcc gtttaacaag
    18301 catattatga ttatcgctgg taaaaattct aagattaatt atctggagcg tttagagtca
    18361 cgcggtgaag gaagtgccaa agcaactgct aatatcacag tagaagtgat tgcacgttca
    18421 ggtgcgcaag tcaagtttgc tgctatcgac cgtctaggtg aaaacgtcac tgcctacatt
    18481 agccgtcgtg gtaaattagg caacgatgca agtattgact gggctatcgg tgtcatgaac
    18541 gaaggaaatg tcgttgctga ttttgatagt gacttgattg gtaatggtag ccatgctgac
    18601 ctcaaggttg tagctctttc aagtggtcgt caggtacaag ggattgatac tcgtgtaact
    18661 aactatggct gcaactctat cggaaatatc ctacaacatg gggttatcct tgaaaaagca
    18721 actttgactt tcaatggtat cggccacatc atcaagggtg ctaagggagc agatgcccaa
    18781 caagagagcc gtgttctcat gctttcagac caagcgcgtt cagatgctaa cccaattctt
    18841 ttgattgatg aaaatgacgt cactgcagga catgcagcct ctattggtca ggtagatcca
    18901 gaagatatgt actacctcat gagtcgtgga ttggataagg caactgcaga gcgtttggtt
    18961 gttcgtggtt tccttggatc tgttatcgtg gagattccag tcaaggaagt tcgtgatgaa
    19021 atgattgcaa ctatcgaaga gaaattgtca aaacgctaag gggaagccta tgttagatgt
    19081 agaagcgatt cgcaaggatt ttccaatttt agatcagatt gtcaatgatg aacctctggt
    19141 ctatctggac aatgctgcga cgacacaaaa accactagta gttctgaaag ctattaacag
    19201 ttactatgag caggacaatg ccaatgttca ccgtggtgtc cataccttag cggaacgagc
    19261 gacagcttct tatgaagctg ctcgtgaaac cattcgtaag tttattaatg caggctctac
    19321 aaaggaagtt ctctttacca gaggaacgac aaccagcctt aactgggtgg cacgctttgc
    19381 tgaggaaatt ctcactgagg gagaccaggt cttgatttca gtaatggaac accattctaa
    19441 tatcattcca tggcaggaag cttgtcgaaa gactggagca gagcttgtct atgtctatct
    19501 taaagacggt gccttggata tggaggattt gcgagctaaa ttgactgata aggttaaatt
    19561 tgtttcccta gctcatgcct ccaatgttct tggtgtggtc aatccgatca aggaaatcac
    19621 tcaattagcc caccaagttg gggcaatcat ggtagtggat ggtgctcaat ctacacctca
    19681 tatgaagatt gatgtccagg acttggatct ggactttttc gccttttcgg gtcacaagat
    19741 ggctggtccg actggtatcg gtgtccttta cggcaaagaa aagtatcttg agcaaatgtc
    19801 tccagtagaa tttggcggcg agatgattga ttttgtctac gagcaatctg ctagttggaa
    19861 ggaattgcct ttgaaatttg aggctggaac gccaaatatg gcaggagcta ttggacttgc
    19921 gactgcagtt gattatctgg aaaagattgg tatggatgcc gttgaagctc atgaacagga
    19981 attgattgcg tacgtctatc caaaactgca ggcaattgag ggattgacca tttacggttc
    20041 tcaggatttg gctcaacgtt cgggtgttat tgcctttaac ctaggtgatc tccatcctca
    20101 cgatcttgcg acggctctgg attatgaagg agtggctgtt cgtgctggtc accattgtgc
    20161 gcaacccttg cttcagtatt tggaagtccc agcaacagct cgtgcaagtt tttatatcta
    20221 taataccaag gcagattgcg acaaactagt cgatgcccta caaaagacaa aggagttttt
    20281 caatggcact ttctaaacta gatagccttt atatggcagt ggtagcagac cattcgaaaa
    20341 atccacatca ccaagggaag ttagaagacg ctgagcaaat cagtctcaac aatccgactt
    20401 gtggagatgt catcaatctc tctgtcaagt ttgatgcaga ggaccgtttg gaagatattg
    20461 cttttctaaa ttcaggatgc acgatttcaa ctgcttctgc tagtatgatg acagatgccg
    20521 ttttaggaaa aaccaaacaa gaaattttag aactggcgac tattttttct gaaatggttc
    20581 aagggcaaaa agatgagcgt caagaccaac ttggagacgc ggcattcttg tcaggtgttg
    20641 ccaaattccc tcaaagaatc aagtgtgcaa ccctagcttg gaatgccctt aagaaaacaa
    20701 ttgaaaatca agaaaaacag taagacaagt ttcttttgtc ttatgaatta ttagaaatga
    20761 agaaagaaag gatattatgg ctgaagaaag agtagaacca aaaccaattg accttggtga
    20821 atataaattt ggtttccatg acgatgtaga gcctgtctta tcgacaggaa aaggactcaa
    20881 cgaaggtgtt attcgtgaat tatctgctgc taagggtgag cctgagtgga tgttggagtt
    20941 ccgtttgaag tcttatgaaa ccttcaaaaa aatgcccatg caaacttggg gagcagactt
    21001 gtcagagatt gactttggtg acttaatcta ctaccaaaaa ccatctgaca aaccagcccg
    21061 ttcttgggat gatgtacctg aaaagattaa agaaaccttt gaacgtatcg ggattccaga
    21121 agctgaacgt gcttatttag caggggcttc tgcccagtac gagtcagaag tggtttacca
    21181 caacatgaag gaagagttcc aaaaattagg tattatcttt acagatacag attccgcact
    21241 caaggaatac ccagacttat ttaatcaata ctttgcgaag ttggtaccgc cgacagataa
    21301 caagttggca gccctcaact cagcagtatg gtcgggtgga acttttatct acgtgccaaa
    21361 aggtgtcaag gtagatattc cacttcaaac ttatttccgt atcaataacg aaaatatagg
    21421 tcagttcgaa cgtaccttga ttatcgttga tgagggagca agcgtccact acgtagaagg
    21481 atgtacagca ccaacatatt caagcaatag cttacacgct gccattgtag aaatttttgc
    21541 tttggacgga gcttatatgc gttatacaac tatccaaaac tggtctgata acgtctataa
    21601 cttggtaaca aagcgtgcta aggctcaaaa ggatgccact gttgagtgga ttgatggaaa
    21661 cttgggtgcc aaaacgacta tgaaatatcc atctgtttac cttgatggag aaggagcgcg
    21721 tggtaccatg ctctctatcg cctttgctaa tgcagggcaa caccaagaca cgggtgctaa
    21781 gatgattcac aatgctccac ataccagctc gtctattgtg tctaaatcca tcgctaaagg
    21841 tggaggaaag gttgactacc gtggacaagt cacctttaac aagaactcta agaaatctgt
    21901 ttcccacatt gaatgtgata ccattatcat ggatgacttg tcagcatcag atactattcc
    21961 atttaatgaa attcacaact cgcaagtggc tttggaacac gaagccaaag tatctaagat
    22021 ttcagaagag caattgtatt atctcatgag ccgtggattg tcagaatctg aggcaactga
    22081 aatgattgtc atgggatttg tagaaccctt tacaaaagaa cttccaatgg aatacgcagt
    22141 tgagctgaac cgcttgatta gctatgaaat ggagggatca gttggataaa atttgatttt
    22201 atactcttcg aaaatctctt caaaccacgt cagcatcgcc ttaccgtatg tatggttact
    22261 gacttcgtca gtttcatcta caacctcaaa acagtgtttt gagcaacctg aggctagctt
    22321 cctagtttgt tctttgattt tgagtattag atttactcaa aatcaaggat tttgaagatg
    22381 aacttgtatc aaaaaatcgc ggtttaaaat cgcgattttt tataatttct cgttaacaaa
    22441 gcggacaaac tgattccacc aaacttttaa gaagaaggct ttttcaattt tcttgtctgc
    22501 taccatttcg aaactagggc gctctgtggt gatgtaacct tgaccaatca agtccttgtc
    22561 ttcataagtc aaatggccaa ccactgttcc agcttcaagt ggtgctggga ttgctttgga
    22621 atcaggtgtg aattgaacag attgggaaga ttgattccca acacgttcga ttagatagat
    22681 atcctctgga gccactgcag ttactgtatc ttcttttcca tcttgtacag gggctttgct
    22741 atcttgatag gcatcgcctt gttgaacgat tttgcgaagt gtaaatgtag aagaaatata
    22801 atccattagg gaagatgtag ctgtaaatcg agcgtaagga ttattgtctt gattatctgc
    22861 atttaaaaca actgtgatga ctctcatgcc tttttcgaca gtagtaccaa caaaagactc
    22921 tccagcctta tctgttgttc ctgtttttag cccatcaaaa ccaccacggt aagcaggcat
    22981 accttctaac atgtagttgg ttgaagtgat tgtcatccca gcaaaagtag aagaaggttt
    23041 tttggtgatt tctaagactt gtgggtattt tttgatgagg ttgcgagcaa cgatagcgac
    23101 atcataagca ctaagcttat tttcctcatc ttttttagaa cctgggtaaa tgttatcccc
    23161 tagagtttca ttgttaagac ctgtcgtatt gacaacagtg gcatcctgaa ttccccattc
    23221 caagagtttt gcccgcatca tatcgacgaa atctttttct gagccagcaa ttttctcagc
    23281 tagggcaata gcggcgctgt tggcactaga taccagagtt gcttcaagca actcttcgac
    23341 agtataatta cgggcctcca taggaatatt actggcttca gaatttgtcg tcaattgata
    23401 aggataatca gaaatatcta caggagtgga gagggtaata cttccgtttt ccaaagcttc
    23461 atagaccaga taaacagtaa tcaattttgt tatggaagca atttcgacag gttgcgttgc
    23521 atccttctca tagagaattt taccagtatt tgcctcaaca gcaatcgcat gtttagcggc
    23581 aatggtaaaa tcttgagcaa cagcagtaga agcaccccct aaaagagaga cagttaacaa
    23641 agttaaaaat atttttttca tagtagtctt attctatcat aaagaaaaaa aatattcttg
    23701 ctttaataat tcatctgtta agctttttga aaatatggta aaataaagtg agggaggtaa
    23761 ctcatgtttc gtagaaataa attatttttt tggaccacag aaattttact cttaaccatc
    23821 atcttttacc tatggagaca gatggggtct ttgattaacc cttttgttag cgtgcttaat
    23881 acaattatga ttccattttt attaggaggc tttctttatt atttgacaaa ccctattgtt
    23941 actttcttaa ataaagtctg taaactcaat cgtttgcttg gtattttaat taccttgtgt
    24001 actttggtct ggggaatggt cataggtgtt gtctatctct tacctatttt gattaatcag
    24061 ttatctagtt tgattatatc tagtcaaact atttatagtc gagtacaaga cttaatcata
    24121 gacttatcta attatcctgc gctccagaat ttggatgtag aagctacaat tcagcagtta
    24181 aacttatcct atgtggatat tcttcaaaat atcctaaata gcgtatcaaa tagtgtgggg
    24241 agcgtcttgt cagctcttat cagtactgtt ttgattttga ttatgactcc agtttttttg
    24301 gtttatttct tattagatgg acataaattc ttgcccatgc ttgaaagaac gattctaaag
    24361 agggatcgct tgcatattgc aggcttatta aagaatttaa atgcgacgat tgctcgctat
    24421 attagtggag tttcgattga cgcaatcatt ataggttgtt tggcttatat tggctatagt
    24481 attattggtt taaaatatgc tttagttttt gccatttttt ctggtgtagc caatttaatt
    24541 ccttatgtgg ggccaagtat tggtttgatt cctatgatca tcgcaaatat attcactgat
    24601 ccccatagac tgctgattgc agtgatttat atgcttgttg ttcagcaggt agatggcaat
    24661 atcttatatc ctcgaatcgt aggaagtgtt atgaaggttc atccaatcac gattttagtt
    24721 ttacttttgt tgtcaagcaa tatctatggt gtagttggaa tgattgtcgc agtgccaacc
    24781 tattctatct tgaaagaaat ttctaagttc ttatcccgtt tgtatgaaaa tcataaaata
    24841 atgaaagaac gagaaagaga attagctaag taaaagtcag gagaaccctg atttttcttt
    24901 actggaagtg gcctttagat tagaagactg aaaataagtt aaagtcttaa actaattttc
    24961 acagctaaga atagtagaag ttaatctgat aaaaatcgaa aaaaccagtg gaattctgtg
    25021 tcagggtaag ttccactggt tttcatagtc tattaaagtt cgaatgaaac ctatttatag
    25081 tagattgaaa ctagaatagt acacctctaa ttctaaaaca ttgttagaaa tcgatttgac
    25141 tgtccttatc tattcgttct attcttattt cattttacta tattttggtg caataagtga
    25201 aaagtagacc gaataatata aggattgatt ttatagtttt taaactcaaa tgaattgaaa
    25261 taaagagagt acgaaaattc tcatctgaaa gtattttaga ataattctct tcgtgaattt
    25321 cttcaaaaca gatagcttca tcttaggtat gtgatttctt tttgcatttt tgagttagat
    25381 aaggtataat ggttttattg tcttttgggg tcgttacgga ttcgacaggc attatgaggc
    25441 atattttgcg actcgtgtgg cgacgtaaac gctcagttaa atataactgc aaaaaataac
    25501 acttcttacg ctctagctgc ctaaaaacca gcaggcgtga cccgatttgg attgctcgtg
    25561 ttcaatgaca ggtcttatta ttagcgagat acgattaagc cttgtctagc ggcttgataa
    25621 gagattgata gactcgcagt ttctagactt gagttatgtg tcgaggggct gttaaaataa
    25681 tacataacct atggttgtag acaaatatgt tggcaggtgt ttggacgtgg gttcgactcc
    25741 caccggctcc attattcctt tgcattcttt tgcattcctt ggtaaaacgt tgttaaatca
    25801 acgtttttta tttttatctt tggtattcct ttgtattctt ttgctaaaaa gggagtcaca
    25861 aacagaccct attttaaaaa aaggatagaa aaaaggatac aacatttgtc gcatcctaaa
    25921 aataatcttt tttcgacgga agacatggga ttcgaaccca cgcacgctat tacacgccta
    25981 ccgcgtttcc aacacggcct cttaagcctc ttgagtaatc ttccaatact tactcaaata
    26041 gtctaccata aaggctctta tcttgcaata aaaattctag aaataagaaa aatgatagat
    26101 tttgaaagaa aatgataaaa aatgcttgac ttcgaaagaa agtatgatag aatgaatagt
    26161 gtaaacgata acaggaggtg attcagtgtt aaaaacagaa cgtaaacaac taattttaga
    26221 ggagttaaat cagcatcatg tagtttctct agaaaaatta gttagtttgc tagaaacgtc
    26281 agaatcaacg gttcgaagag acttggatga gttggaagcg gaaaacaagc ttcgtcgtgt
    26341 gcatggtgga gcagaactcc cccactcctt acaggaagaa gaaaccattc aagaaaaatc
    26401 tgtcaaaaac cttcaagaaa agaagttgct ggctcagaaa gcagcctctc tcattaaaga
    26461 aaaagatgtc atctttatcg atgctggaac aacaactgct tttttgattc atgaattggt
    26521 caataagaat gttacagttg tgaccaactc cattcaccat gccgctcagt tggttgaaaa
    26581 gcagattcca actgtcatgg ttggaggaaa cgtcaagacg gcgacagatg ctagtatcgg
    26641 gggcgttgct cttaaccaga ttaaccaatt gcactttgac cgtgccttta tcggaatgaa
    26701 tggtgttgac gatggctatt atacgactcc tgatatggag gagggagctg tgaaaagagc
    26761 tattttggag aatgccaagc agacctacgt cttggtggat tcgtcaaaaa ttggacaaac
    26821 ttgctttgcc aaggtagcac cactcaaacg cgctatcgtt atcactagtc aagggcatga
    26881 gctcttgcag gttattaagg agaaaacgga ggtaatagaa gtatgattta tacagtcaca
    26941 ctcaatccat ccattgacta tatcgttcgt ttggaccaag tcaaagttgg tagtgtaaat
    27001 cgtatggaca gtgatgataa gtttgctggt gggaaaggaa tcaatgtcag ccgtgtcttg
    27061 aaacgtttga atataccaaa tacagcgacg ggatttatcg gtggctttac tggtaaattt
    27121 atcacagata ctttagcaga ggaagaaatc gagacacgtt ttgtccaggt ggcagaagat
    27181 actcgtatca atgttaaaat caaagcagac caagaaacag aaatcaacgg aacgggtcca
    27241 actgttgaac cggttcagct agaagaattg aaagctattt tatctagtct gacagcagaa
    27301 gatacagttg tctttgcagg ttcaagtgct aaaaatctag gcaatgttat ctataaggat
    27361 ttgatttcct tgacgcgcca gactggtgcg caagtggtct gtgactttga aggacagacc
    27421 ttaattgata gtttggacta ccagcctctt cttgtaaaac caaacaatca tgaacttgga
    27481 gcgatttttg gggttaaact cgaaagttta gatgaaattg agaaatacgc tcgtgagtta
    27541 ctggctaagg gtgctcaaaa tgttattatc tctatggctg gtgatggcgc ccttcttgtc
    27601 acatctgagg gagcttactt cgctaaacca atcaaaggaa cagtcaaaaa ttcagttgga
    27661 gctggtgatt ctatggttgc tggattcaca ggtgaatttg tcaaatcaaa agacgcagta
    27721 gaagccttca aatggggagt ggcttgcgga acggcaacta ccttctcaga tgacttggca
    27781 acggcggaat ttattaaaga aacatatgga aaagttgagg tagaaaaaag atgaaaattc
    27841 aagacctatt gagaaaagat gtcatgttgc tagatttgca ggcaactgaa aaaacagctg
    27901 tcatcgacga gatgattaaa aatttgacag agcacggtta tgtaacagat tttgaaacat
    27961 ttaaagaagg aattttggcg cgtgaagctt tgacttctac tggtttgggt gatggaatcg
    28021 caatgcctca cagcaaaaac gctgctgtca aagaagcgac agttctattt gctaagtcaa
    28081 ataagggtgt tgactacgag agcttggatg gacaagcaac tgacctcttc ttcatgattg
    28141 cagctccaga aggtgccaat gatactcact tggcagcctt ggcagaattg tctcaatact
    28201 tgatgaaaga cggttttgca gacaaacttc gtcaagcaac atctgcagac caagttatcg
    28261 aactttttga ccaagcttca gaaaaaactg aggaacttgt tcaagcacct gctaatgact
    28321 ctggtgactt tatcgtagct gttacagctt gtacaacagg tattgcccac acttacatgg
    28381 cccaagaagc ccttcaaaaa gtagctgctg aaatgggggt tggtatcaag gtcgaaacca
    28441 acggtgctag cggtgttgga aatcaactaa ctgcagaaga tatccgtaag gctaaagcta
    28501 ttatcattgc agcagacaag gccgttgaaa tggatcgatt tgatggaaaa ccattgatca
    28561 atcgtccagt tgctgacggt atccgtaaga cagaagagct aattaacttg gctctttcag
    28621 gagatactga agtctaccgt gccgctaatg gtgccaaagc tgcaacagcc tctaacgaaa
    28681 aacaaagcct tggtggtgcc ttgtacaaac acttgatgag tggtgtatct caaatgttac
    28741 cattcgttat cggtggtggt atcatgattg cccttgcctt cttgattgac ggtgctttgg
    28801 gtgttccaaa tgaaaacctt ggcaatcttg gttcttacca tgagttagct tctatgttca
    28861 tgaaaattgg tggagctgcc tttggtttga tgcttccagt ctttgcgggt tatgttgcct
    28921 actctattgc tgaaaaaccg ggtttggtag caggtttcgt ggctggtgct attgccaaag
    28981 aaggttttgc ctttggtaaa attccttatg ccgcaggtgg tgaagcaact tcaactcttg
    29041 caggtgtctc atctggtttc ctaggtgccc ttgttggtgg atttatcgca ggtgccttgg
    29101 ttcttgccat caagaaatac gttaaagttc ctcgttcact cgaaggtgct aaatcaatcc
    29161 ttctattgcc acttcttgga acaatcttga caggatttgt tatgctagct gtgaatatcc
    29221 caatggctgc aatcaacact gctatgaatg acttcctagg cggtcttgga ggaggttcag
    29281 ctgtccttct tggtatcgtc cttggtggaa tgatggctgt tgacatgggt ggaccagtta
    29341 ataaagcagc ttatgtcttt ggtacaggta cgcttgcagc aactgtttct tcaggtggtt
    29401 ctgtagccat ggcagcagtt atggctggag gaatggtgcc accacttgca atctttgtcg
    29461 caactcttct tttcaaagat aaatttacta aggaagaacg taactctggt ttgacaaaca
    29521 tcatcatggg cttgtcattt atcactgagg gagcgattcc atttggtgcc gctgacccag
    29581 ctcgtgcgat tccaagcttc atccttggtt cagcagtagc aggtggactc gttggtctta
    29641 ctggtatcaa actcatggcg ccacacggag gaatcttcgt tatcgccctt acttcaaatg
    29701 ctctccttta cctcgtttct gtcttggtag gagcaatcgt aagtggtgtg gtttatggtt
    29761 acctacgcaa accacaagca taaaaaatag aaaaatgaaa agattggacc gtttggtgca
    29821 gtctttttct cttcccgaaa tgcctgtgaa atatggtata atagaagaat ggcaaacaag
    29881 aatacaagta caacaagacg gagaccgtct aaagcagaac tggaaagaaa agaagcgatt
    29941 caacgaatgt tgatttcgtt aggaattgcg attttattga ttttcgcagc cttcaaatta
    30001 ggggctgcag gtataaccct ttataattta attcgcttgc tagtgggtag cctagcttat
    30061 ctggcgatat tcggcctatt aatctatctc ttctttttca agtggatacg aaaacaggaa
    30121 ggactcttat ctggcttttt caccatattt gctggcttac tcttgatttt tgaggcctac
    30181 ttggtttgga aatatggttt ggacaagtcc gttctaaaag ggaccatggc tcaggttgtg
    30241 acagatctga ctggttttcg aacgactagc tttgctggag ggggcttgat cggggtcgct
    30301 ctttatattc caacagcctt tctcttttca aatatcggaa cttactttat tggttctatc
    30361 ttgattttag tgggttctct cctagtcagc ccttggtctg tttacgatat tgctgaattt
    30421 ttcagtagag gctttgccaa atggtgggaa gggcacgagc gtcgaaaaga ggaacgcttt
    30481 gtcaaacaag aagaaaaagc tcgccaaaag gctgagaaag aggctagatt agaacaagaa
    30541 gagactgaaa aagccttact cgatttgcct cctgttgata tggaaacggg tgaaattctg
    30601 acagaggaag ctgttcaaaa tcttccacct attccagaag aaaagtgggt ggaaccagaa
    30661 atcatcctgc ctcaagctga acttaaattc cctgaacagg aagatgactc agatgacgaa
    30721 gatgttcagg tcgatttttc agccaaagaa gcccttgaat acaaacttcc aagcttacaa
    30781 ctctttgcac cagataaacc aaaagatcag tctaaagaga agaaaattgt cagagaaaat
    30841 atcaaaatct tagaagcaac ctttgctagc tttggtatta aggtaacagt tgaacgggcc
    30901 gaaattgggc catcagtgac caagtatgaa gtcaagccgg ctgttggtgt aagggtcaac
    30961 cgcatttcca atctatcaga tgacctcgct ctagccttgg ctgccaaaga tgtccggatt
    31021 gaagcaccaa tccctgggaa atccctaatc ggaattgaag tgcccaactc cgatattgcc
    31081 actgtatctt tccgagaact atgggaacaa tcgcaaacga aagcagaaaa tttcttggaa
    31141 attcctttag ggaaggctgt taatggaacc gcaagagctt ttgacctttc taaaatgccc
    31201 cacttgctag ttgcaggttc aacgggttca gggaagtcag tagcagttaa cggcattatt
    31261 gctagcattc tcatgaaggc gagaccagat caagttaaat ttatgatggt cgatcccaag
    31321 atggttgagt tatctgttta caatgatatt ccccacctct tgattccagt cgtgaccaat
    31381 ccacgcaaag ccagcaaggc tctgcaaaag gttgtggatg aaatggaaaa ccgttatgaa
    31441 ctctttgcca aggtgggagt tcggaatatt gcaggtttta atgccaaggt agaagagttc
    31501 aattcccagt ctgagtacaa gcaaattccg ctaccattca ttgtcgtgat tgtggatgag
    31561 ttggctgacc tcatgatggt ggccagcaag gaagtggaag atgctatcat ccgtcttggg
    31621 cagaaggcgc gtgctgcagg tatccacatg attcttgcaa ctcagcgtcc atctgttgat
    31681 gtcatctctg gtttgattaa ggccaatgtt ccatctcgtg tagcatttgc ggtttcatca
    31741 ggaacagact cccgtacgat tttggatgaa aatggagcag aaaaacttct tggtcgagga
    31801 gacatgctct ttaaaccgat tgatgaaaat catccagttc gtctccaagg ctcctttatc
    31861 tcggatgacg atgttgagcg cattgtgaac ttcatcaagg ctcaggcaga tgcagactac
    31921 gatgagagtt ttgatccagg tgaggtttct gaaaatgaag gagaattttc ggatggagat
    31981 gctggtggtg atccgctttt tgaagaagct aagtctttgg ttatcgaaac acagaaagcc
    32041 agtgcgtcta tgattcagcg tcgtttatca gttggattta accgtgcgac ccgtctcatg
    32101 gaagaactgg agatagcagg tgtcatcggt ccagctgaag gtaccaaacc tcgaaaagtg
    32161 ttacaacaat aaaaaaatag cttctttccg agtttggagg gaagctattt tagtggctat
    32221 tgattacttt tatactcttc gcaaatctct tcaaaccacg tcagcttcgc cttgccgtac
    32281 tcaagtactg tctacggcta gcttcctagt ttgctctttg attttcattg agtattattt
    32341 tctgaagttg gagtattggg ctgtttttca ttttcagtgg caggtttact tgtagcaggt
    32401 gtagtagagt cctgagttgc tgttttctga tcttcttttt tctcttcctt gacgctagat
    32461 tttggcgttt cttcttgttg tgttttttct tgagaagtgt tattttcctt atttggagta
    32521 gtattttcct gaggggattc tttttgaatt tctttgacaa aggttgtcgt ctggcttgtc
    32581 gtaggttctt ttttagtatt tttattatta ttatccaagg cgttcatgat cgtgataccc
    32641 gcggtaatca aaccaaggat actaccgata gtagtaatgg ttttttgaaa aacagtaaag
    32701 ccttttttga tatgttctgt tttcggtttt gaagttctac gatagttaga catacattct
    32761 ctcctttgat tatgatttat tatactctgt ttctttaaaa aaatcttaaa aaaagagaaa
    32821 ttgccctttc ttgtcgcagg ctccgtttca tgatacaata gaaggagtga ttttagaaag
    32881 cgtgagaaac atgatttact ttgataattc ggcgacgacc aggccctatc cagaagccct
    32941 tgaaacctat atgcaggtgg cttcaaaaat tttaggaaat ccatctagtc tccatcgttt
    33001 gggagaccag gcaacacgaa ttttagatgc ttcccgtcaa cagattgcag atttaatcgg
    33061 taagaaaagt gatgaaatct tctttacatc tggtgggaca gaaggggata actggatcat
    33121 caagggagta gcatttgaaa aagcccagtt tggcaagcac atcatcgtat cagccattga
    33181 acatccagca gttaaggaat cagccctctg gttgaaagct caaggttttg aagtggattt
    33241 tgctccagtt gataacaaag gatttgtgga tgttgaggcg ctagaagatt tgataagacc
    33301 tgatacgacc ctcgtttcca tcatggctgt gaacaatgaa atcggctcta tccaacctat
    33361 tgaggctatt tcagaattct tggcagacaa gccaactatt tccttccacg ttgatgcggt
    33421 tcaggcgctt gccaagattc cgactgaaaa gtatctgaca gaacgagtgg atttcgcgac
    33481 tttctctggt cacaagttcc acggaatccg tggtgttggt tttatctata tcaagtctgg
    33541 caagaagatt acgcctcttt taacaggtgg tggtcaggaa cgtgattacc gttcgacaac
    33601 tgaaaatgtg gcaggaattg cagcgaccgc taaggctctc cgtttatcta tggaaaagct
    33661 agatatcttt aggagcaaga ctgggcagat gaaggcagtg attcgtcaag cacttctgga
    33721 ctatccggat atatttgtct tttcagatga ggaagacttc gcccctcata ttctgacttt
    33781 tggaatcaag ggtgttcgtg gtgaggtcat tgttcacgcc tttgaagact atgatatttt
    33841 catctcaacg acctcggctt gttcgtccaa ggctgggaaa ccagccggaa ccctgattgc
    33901 tatgggagtg gacaaggata aggctcagtc agctgtgcgt cttagtctag accttgaaaa
    33961 tgatatgagt caggtcgagc agttcttgac caagctaaaa ttaatttaca atcaaactag
    34021 aaaagtaaga taggagcatt catgcagtat tcagaaatta tgattcgcta cggtgagctg
    34081 tcaaccaagg gcaaaaatcg tatgcgtttc atcaataaac ttcgcaataa tatttcagac
    34141 gttttgtcta tctatcccca agttaaggta acagcagatc gcgaccgtgc ccacgcttac
    34201 ctcaatggag cagattacac agcagtagca gaatcgctca aacaagtatt tggaattcaa
    34261 aacttttccc ctgtttataa ggttgaaaaa tctgtagaag ttctgaagtc tgctgtccaa
    34321 gagattatgc aggacatcta caaggaaggc atgaccttta aaatctctag caagcgtagc
    34381 gaccacacct ttgaattgga cagtcgtgaa ctcaaccaaa cgcttggagg ggctgtattc
    34441 gaagccattc caaacgtaca agctcaaatg aaaagtcctg acatcaatct tcaggtggag
    34501 atacgtgaag aagcagccta tctttcttat gaaaccgttc gaggggcagg tggattacca
    34561 gtgggaactt ctggtaaggg catgctcatg ttgtcagggg gaatcgattc ccctgtagct
    34621 ggctatctag cgcttaaacg aggggtagat atagaggcag ttcactttgc cagcccacct
    34681 tacacgagtc ctggtgctct taaaaaagcc caagatttga cccgtaaatt aaccaaattt
    34741 gggggaaata tccagtttat cgaagttcct tttacagaga ttcaagagga aatcaaagcc
    34801 aaagcgccag aagcctacct tatgaccttg acgcgtcgtt ttatgatgcg tattacggac
    34861 cgtattcgtg aggtacgaaa tggtttagtt atcatcaatg gggaaagtct aggtcaagta
    34921 gccagccaaa cccttgaaag tatgaaggct atcaatgctg ttaccaacac tcccatcatt
    34981 cgtcctgtgg ttaccatgga caagttggaa atcattgaca tcgcccagga aatcgatacc
    35041 tttgacattt caatccaacc gtttgaagac tgttgtacta tttttgcacc agatcgtcca
    35101 aaaacaaatc ctaaaattaa gaatgcggag cagtacgaag cgcgtatgga tgttgaaggc
    35161 ttggttgagc gagcagtggc tggaatcatg attactgaaa tcacacctca agccgaaaaa
    35221 gatgaagttg atgacttgat tgacaatctg ctctaattca gaaaatccaa aagaatagcg
    35281 aaaatcagta aaaaaagtta gttttttctc taaaaacagg taaaaaacta acttttttta
    35341 tttttatgat ataatgatat aaaattttga atatagagag ttttctgaca atgaatcaat
    35401 cctactttta tctaaaaatg aaagaacaca aactcaaggt tccttataca ggtaaggagc
    35461 gccgtgtacg tattcttctt cctaaagatt atgagaaaga tacagaccgt tcctatcctg
    35521 ttgtatactt tcatgacggg caaaatgttt ttaatagcaa agagtctttc attggacatt
    35581 catggaagat tatcccagct atcaaacgaa atccggatat cagtcgcatg attgtcgttg
    35641 ctattgacaa tgatggtatg gggcggatga atgagtatgc ggcttggaag ttccaagaat
    35701 ctcctatccc agagcagcag tttggtggta agggtgtgga gtatgctgag tttgtcatgg
    35761 aggtggtcaa gccttttatc aagcacaaaa caggttggtt tgatggcatg atgacgacag
    35821 gttgctctat gggagcctat catgcactca atttcttcct ccagcatcca gatgtcttta
    35881 ccaaagtgat tgctctcagt ggtgtttacg acgcacgttt ctttgtcggc gattactaca
    35941 acgatgatgc tatttaccaa aactcgccag tagattatat ttggaaccaa aacgatggct
    36001 ggtttattga ccgttaccgt caggcagaga ttgtgctgtg tacggggctt ggagcctggg
    36061 aacaagatgg tttaccatcc ttttacaagc tcaaagaagc ctttgaccag aaacaaattc
    36121 cagcctggtt tgctgaatgg ggacatgatg tcgcccacga ctgggaatgg tggcgtaaac
    36181 aaatgcttta tttcctcggt aatctctatt tataaaagga gttacctatg aattaccttg
    36241 ttatttctcc ctactatcca caaaactttc aacagtttac catcgaacta gctaataaag
    36301 gcatcacagt cttgggaatt ggtcaagagt cttacgagca attggatgag cccttgcgca
    36361 atagcttgac cgagtatttt cgtgttgata atcttgagaa catagatgaa gtcaaacgtg
    36421 cagttgcttt tctcttttat aaacatggtc caattgaccg catcgagtct cacaatgaat
    36481 actggcttga gctagacgca acactcagag aacaattcaa tgtttttggt gccaaaccag
    36541 aggatctcaa aaagacgaaa tataagtctg aaatgaagaa acttttcaaa aaagcaggtg
    36601 ttcctgtggt acctggagct gttatcaaga cggaagcaga tgttgatcaa gcagtgaaag
    36661 aaatcggtct tccaatgatt gccaaacctg ataatggagt gggagcagcc gcaaccttta
    36721 aacttgagac agaagacgat atcaatcact tcaagcaaga atgggaccat tcaacccttt
    36781 atttctttga aaaatttgtc acttccagcg aaatctgtac ctttgacggg ctcgtggaca
    36841 aggatggaaa gattgtcttc tcaacaacct ttgactacgc ctatacaccg cttgacctca
    36901 tgatttataa gatggacaat tcttattatg tgctcaagga tatggatcct aaactgcgca
    36961 agtatgggga agcaattgtc aaagaatttg gtatgaaaga acggtttttc catattgagt
    37021 tcttccgtga gggggacgat tatattacca tcgagtacaa taaccgccct gcaggtggtt
    37081 ttaccattga tgtttataac tttgctcatt ccttggacct ttatcgtggc tatgcagcta
    37141 ttgtcgcagg agaggagttc ccggcgtcag actttgaaac tcagtattgt ttggctactt
    37201 ctcgccgtgc aaatgctcac tatgtttatt cagaagagga tttgcttgcc aaatatagcc
    37261 agcagttcaa ggttaaaaaa gtcatgccag ctgccttcgc ggaacttcaa ggagattacc
    37321 tgtatatgct gacaactccg agtcgacaag aaatggatca gatgattgct gatttcggac
    37381 aacgtcaaga ataagaacta tcggattaag gaaattcact cccttaatcc ttttgttttg
    37441 tctggtaaaa aataagagca tcctaacaag gtagctatca taaaacttgt tcgataacta
    37501 tttgaagcag gattaggtgg ctagaaattg aattttaaca tttcaattta gtcatagtat
    37561 tgtgttttcg tatccttaaa tcagctaaaa ggatccatga cgacacctat acgatatagt
    37621 tttcaggata ccaaaccagt ctattaatac tcaatgaaaa tcaaagagca aactaggaag
    37681 ctagccgcag gttgctcaaa acactgtttt gaggttgtgg atagaactga cagagtcagt
    37741 atcatatacc tacggcaagg tgaagctgac gtggtttgaa gagattttcg aagagtataa
    37801 aatattcagg tgacgcatag atatagttaa ttgaagcttt gtttgaaatc tgataaaata
    37861 atgatattac taagttttaa aaactaaaga aaagggaaga tatgattaca ggcgaattaa
    37921 aaaataaaat cgatcagctg tgggaaattc tttggacaga aggaaacgca aatcctttaa
    37981 caaatattga acagttgact tatctcttat ttatgaaaga tttggatagt gtcgagcttg
    38041 gacgtgaaag tgatgctgaa tttctaggga ttccttatga gggagttttt ccaaaagata
    38101 aacctgaata ccgttggtca acttttaaaa atataggaga tgctcaggaa gtttatcgtt
    38161 taatgactca ggagattttt ccgtttatta aaaatctcaa gggggataca gatgatacag
    38221 ccttttcacg atatatgcga gaagctattt ttcaaataaa taaacctgct acgcttcaaa
    38281 aggcaatttc tatcttagat gtttttccaa ctaggggatt agatgtagat tttgataatg
    38341 acaaacaaag tattactgat atcggagata tctatgaata tctgttatca aaattgtcga
    38401 ccgcaggtaa aaatggacag ttccgtacac ctcgtcacat catcgatatg atggttgagt
    38461 tgatgcaacc gactatcaaa gatatcatct cagatcccgc tatgggttct gctggcttct
    38521 tagtatctgc tagccgttac ttaaagcgta agaaagatga atgggaaacc aatacagata
    38581 atatcaatca ttttcataat cagatgtttc atggaaatga tacggatacg actatgttga
    38641 gacttggggc gatgaacatg atgctacatg gagtagaaaa tccacaaatc agttaccttg
    38701 actcgctgtc tcaagataat gaagaagccg ataaatatac tttggtttta gcaaatcctc
    38761 cttttaaggg ctcacttgac tacaattcaa cctctaatga ccttcttgca accgtaaaaa
    38821 ccaaaaaaac agaattactc tttctttctc ttttcttgcg aactttaaaa ccaggtggac
    38881 gagcagcagt tatcgtacct gatggtgtcc tttttggttc gtctaaagct cataaaggaa
    38941 ttcgtcagga aattgtagag aatcataagc ttgatgctgt aatctcaatg cctagtggtg
    39001 tgttcaagcc ttatgctgga gtttcaactg ccattctcat ctttacaaaa actggtaatg
    39061 gtggtactga caaagtctgg ttttacgata tgaaagcgga tggtttaagt ttggatgata
    39121 agcgacaacc gattagcgac aatgatattc cagatattat cgaacgcttt catcatcttg
    39181 aaaaagaagc agaacgtcag agaacggatc aatctttctt tgttccagtt gctgagataa
    39241 aggaaaatga ttatgatttg tctatcaata aatataaaga gattgagtat gaaaaagttg
    39301 agtatgaacc aacagaggtc atcttaaaga aaatcaatga tttagaaaaa gaaattcaag
    39361 ctggcttggc tgaattagaa aaattactca agtagggagg tggctgtatg aaaaaagtga
    39421 agttggggga agtcttatct ctaaaaaaag gcaagaaagc cactgtactt gctgaacaaa
    39481 caactctaag ccaacgttat attcaaatag atgatttaag aaataataat aatttaaaat
    39541 tcactgaaag tttaaatatg actgaagcac tcccagatga tattctgata gcatgggatg
    39601 gagctaatgc aggaacagtt ggttatggat tatcgggagc tgttggtagt acaattacgg
    39661 tcttaaaaaa gaatgagcga tacaaagaaa aaattatatc agattacttg ggagtctttt
    39721 tggaaagtaa atcgcagtat ttacgagaac attcaacagg tgcaacaatt cctcatttaa
    39781 acaagaatat attacttgat ttacaattag aattgctagg tatcgaagaa caagagaaca
    39841 ttatctgtat tcttaatacg attaaagggc ttattactaa aagaaaattg cagttagatg
    39901 aactaaactt gctcgtcaaa tcccgattta acgagatgtt tggggaaaat aaaatatttg
    39961 aaagcattga taacttattt gatattatag atggtgatag gggcaaaaat tatcctaaat
    40021 cagatgagtt gtttagtgag gagtactgtt tatttttaaa tacaaagaat gttactaaaa
    40081 acggattttc attcgataca aagcaattta tcactaaaac aaaggataaa ttacttcgaa
    40141 aaggcaaact tgagcgttat gatatagtct tgacaacaag aggtactgtt ggaaatgtag
    40201 cgtactacga tgaattaata aaatataaac atttacgtat aaattcaggt atggtaatat
    40261 tacgtcccaa gacaccaaat ctaaatcaca attggcaatc caaaaatctc tggaagaact
    40321 tgaaactttg aagaaatctc tgatgcagga gtattttggc tgatattctg ccattgtaat
    40381 tacggtaatg atttgttata atacttcaaa ggaggaaatc agatggtagt aaaaacaaga
    40441 aaacaaggaa attcaatcac cattacgatt ccaagtgaat ttaatattcc aagtggtgtt
    40501 aaatacgaag cgaaattgtt accaagtggt gagattatct ttactcctga agaattgggg
    40561 cagcaggttt cttatgtatc tgatgatgcc tttgacttaa atttagataa aatatttgac
    40621 gaatacgacg atgttttcaa agctttggtg gaaaaatgac aatctatctg acagaaaagc
    40681 aaattgaaaa aataaatgct ttagcaattc aacggtattc tccaaatgag aaaattcaaa
    40741 cagttagttc ttctgcctta aatatgattg tgaacttacc agaacaattt gtctttggga
    40801 agtctcttta tccaacaatt tttgataaag caacgatact atttgtccaa ttgataaaga
    40861 agcatgtttt tgctaatgct aataaaagaa ctgctttctt cgttttggtc aaatttttac
    40921 aattaaacgg ctatcgtttt tctgtaacgg tagaagaagc agtaaaaatg tgtgtaacca
    40981 tcgcagtaga agctttaact gatgaaaaaa tgacaagcta ctccaaatgg gtttctgaac
    41041 attctgttag agaaaaggtc aaaaagtaac ctagtatgct ggatttgaat gagcacaaga
    41101 aaataaatga acagacaata ttagaattct gtaatgcaga aactgatatt gtctcttttt
    41161 attgatgaat aagaaagtga gaaattatgg aatcaaaagt tacaattatc atgcaagaaa
    41221 tgttacctct tttaaataat gaacaattac tagcgttgag agagagttta gaacatcatc
    41281 tagtagacgg aaaaaagcag cagaagtatt cgaataataa cctgttgcaa ctatttatta
    41341 ccgccaagca ggtagagggc tgtagctcaa aaacaattcg ttattaccag aggacgattg
    41401 aaaacttgtt taatgctatt aaagagtctg tgacacaact cacaacagat gatttaagga
    41461 gttatttagc aaattaccag tctgaaaagg attgtagtaa ggcaaattta gacaatatta
    41521 ggcgtatatt gtcttctttt tttgcttggc ttgagcaaga ggaatatatc attaaaaatc
    41581 ccattcgacg gataaagaaa attaagactg agcaaaatgt gaaggaaact tatactgatg
    41641 aacatttgga aattatgcgt gataactgtg aaaatttgag agatttggca ataatagacc
    41701 tactagcatc gacaggtatg cgtgtagggg agcttgtaca gttgaatcgt tcagatattg
    41761 attttgaaaa cagagagtgt gttgtctttg gtaaaggaaa gaaggagaga ccagtatatt
    41821 ttgacgctcg gacgaaaatt catttaagaa attatcttaa cgacagaaaa gatagtcacc
    41881 ctgctctttt tgtaacgcta gttggaaaag cccagagact tggaattgct ggtgtagaga
    41941 ttcgcttaag aaagttagga gacaaactcg gcatacaaaa ggttcaccca cataagttca
    42001 gaagaacttt agcgactaag gcaattgata aaggtatgcc tatcgaacaa gtccaaaaac
    42061 tgctaggtca tagcaagatt gacacaaccc tggcctatgc catggtcaat caaaataatg
    42121 tcaagcattc acaccaaaaa ttcatctctt aaaagcaaat ccc
//
LOCUS       DBEJHE010000018        40650 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC4 isolate 671759
            SAMN38261586-rid24793303.denovo.18, whole genome shotgun sequence.
ACCESSION   DBEJHE010000018 DBEJHE010000000
VERSION     DBEJHE010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261586
            Sequence Read Archive: SRR26833752
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 40650)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40650)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576136.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576136.1
            Genome Coverage       :: 109x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 19:48:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,067
            CDSs (total)                      :: 2,029
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 131
            CDSs (without protein)            :: 131
            Pseudo Genes (ambiguous residues) :: 0 of 131
            Pseudo Genes (frameshifted)       :: 64 of 131
            Pseudo Genes (incomplete)         :: 59 of 131
            Pseudo Genes (internal stop)      :: 46 of 131
            Pseudo Genes (multiple problems)  :: 32 of 131
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40650
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261586-rid24793303.denovo.18"
                     /strain="GPSC4"
                     /isolate="671759"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            117..347
                     /gene="blpU"
                     /locus_tag="ACL3EZ_001268"
     CDS             117..347
                     /gene="blpU"
                     /locus_tag="ACL3EZ_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpU"
                     /protein_id="HGR0392833.1"
                     /translation="MNTKTMSQFEIMDTEMLACVEGGGCNWGDFAKAGVGGGAARGLQ
                     LGIKTRTWQGAATGAVGGAILGGVAYAATCWW"
     gene            350..475
                     /locus_tag="ACL3EZ_001269"
     CDS             350..475
                     /locus_tag="ACL3EZ_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PncF family bacteriocin immunity protein"
                     /protein_id="HGR0392834.1"
                     /translation="MDFKSFIIGLVVGIFGPYMDDLIRKKFLKSSEKKTEKSVKK"
     gene            886..1080
                     /locus_tag="ACL3EZ_001270"
     CDS             886..1080
                     /locus_tag="ACL3EZ_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0392835.1"
                     /translation="MKKVLKYFLVFVFLFLMNIFIFKILATLGFQLIMSEKSYIVLPL
                     FSLIVLYMIDKRIRKKKKSL"
     gene            1101..1994
                     /locus_tag="ACL3EZ_001271"
                     /pseudo
     CDS             1101..1994
                     /locus_tag="ACL3EZ_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000343891.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            2525..2821
                     /locus_tag="ACL3EZ_001272"
     CDS             2525..2821
                     /locus_tag="ACL3EZ_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uberolysin/carnocyclin family circular
                     bacteriocin"
                     /protein_id="HGR0392836.1"
                     /translation="MKSKRMEFHNKFLIVSAMLAVISWLSLGVVSFPMLAGTLGISTK
                     AAATVVNLISAYSTVTAVISIVGAITGVGSIGSGIAATVLYILKKKGAAKAALW"
     gene            2828..3964
                     /locus_tag="ACL3EZ_001273"
     CDS             2828..3964
                     /locus_tag="ACL3EZ_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0392837.1"
                     /translation="MKILSKKECESILGYLNFIGITLLFFVIISLSIYFKSYLPFQGK
                     LFLLFLVVDYATLNRYNMKLPIQSKKINTFYIRKNYIFLYLLAIVKKYYSFQILQSFI
                     YLFILYFLDIIGYFYLSITLCLIAIQIISLILPSLFSIISKLFLFLSIGLLSIEQGQV
                     VIYVILLNYFILVMGILDNHASNFYFKSSRMSQKRFRSSLFILLRFCWLNKGLTFSFI
                     LISILLSYLFWYMMTMLSIDDTKIPILFLYTSIYITLMEAIIGNHKSSIGVDLALLQL
                     SALNHSKMNFFFKNAQLMMLTHLISFLQFSLLLCLIPVTSYSNDIKSILLNLLLIPFN
                     YFIAYVYYKKALFLIKGTVSLLRWSFLVLYCFLIIFVILVGGIR"
     gene            3961..4443
                     /locus_tag="ACL3EZ_001274"
     CDS             3961..4443
                     /locus_tag="ACL3EZ_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein M"
                     /protein_id="HGR0392838.1"
                     /translation="MRKSGFLIYYVLFCIVCFLLGLLLSFILKNETFATIPPKLELQF
                     TLTVLQANSTNFLLYLFCFPISPLLQLFDLLSLGIQLGISGQMIGIVATIKGILPHAL
                     IEIPNFIWYQGMSQYLLYRLLKDRGIKNILIYIKSNLKWYIISYLLLILAALIEGIKL
                     "
     gene            4440..5036
                     /locus_tag="ACL3EZ_001275"
     CDS             4440..5036
                     /locus_tag="ACL3EZ_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000687786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGR0392839.1"
                     /translation="MKIENESKSYDKCILKNISLEIDKGIYRVEGENGSGKSTLLQLL
                     AGLETFDSGLKNCVSKDVLYLDTNQLGVVPFTIEENLQLLCDSFQIHLSFEDKEQINT
                     FFDNKIGDNYMTASTGTKFKLGLSLIFAKNWDYIFIDETLSTVDARSIDMIAKRLISM
                     KESSTIIYVSHNLLNQELISKSQRILIEEGRVYEISNK"
     gene            5017..5508
                     /locus_tag="ACL3EZ_001276"
     CDS             5017..5508
                     /locus_tag="ACL3EZ_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0392840.1"
                     /translation="MKFQTNNSLYKLMNLIIYLFLLYLFIDLLMKSGILDEQIDKLSE
                     LSNLFTIKIETILTVISVVFTFIATLIEYGFSLFLITLFFDKNKRNFGDILLSKNITL
                     SFSILLCYLFNPSDIKFAYFSVLTVLLIGITNYARFKNLRLTVVFSVPFLFNAIMSII
                     NSF"
     gene            5888..8041
                     /gene="comA"
                     /locus_tag="ACL3EZ_001277"
     CDS             5888..8041
                     /gene="comA"
                     /locus_tag="ACL3EZ_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter ComA"
                     /protein_id="HGR0392841.1"
                     /translation="MKFGKRHYRPQVDQMDCGVASLAMVFGYYGSYYFLAHLRELAKT
                     TMDGTTALGLVKVAEEIGFETRAIKADMTLFDLPDLTFPFVAHVLKEGKLLHYYVVTG
                     QDKDSIHIADPDPGVKLTKLPRERFEEEWTGVTLFMAPSPDYKPHKEQKNGLLSFIPI
                     LVKQRGLIANIVLATLLVTVINIVGSYYLQSIIDTYVPDQMRSTLGIISIGLVIVYIL
                     QQILSYAQEYLLLVLGQRLSIDVILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSII
                     DALASTILSIFLDVSTVVIISLVLFSQNTNLFFMTLLALPIYTVIIFAFMKPFEKMNR
                     DTMEANAVLSSSIIEDINGIETIKSLTSESQRYQKIDKEFVDYLKKSFTYSRAESQQK
                     ALKKVAHLLLNVGILWMGAVLVMDGKMSLGQLITYNTLLVYFTNPLENIINLQTKLQT
                     AQVANNRLNEVYLVASEFEEKKTVEDLSLMKGDMTFKQVHYKYGYGRDVLSDINLTVP
                     QGSKVAFVGISGSGKTTLAKMMVNFYDPSQGEISLGGVNLNQIDKKALRQYINYLPQQ
                     PYVFNGTILENLLLGAKEGTTQEDILRAVELAEIREDIERMPLNYQTELTSDGAGISG
                     GQRQRIALARALLTDAPVLILDEATSSLDILTEKRIVDNLIALDKTLIFIAHRLTIAE
                     RTEKVVVLDQGKIVEEGKHADLLAQGGFYAHLVNS"
     gene            8054..9403
                     /gene="comB"
                     /locus_tag="ACL3EZ_001278"
     CDS             8054..9403
                     /gene="comB"
                     /locus_tag="ACL3EZ_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence pheromone export protein ComB"
                     /protein_id="HGR0392842.1"
                     /translation="MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKE
                     MSLSTRATVEPSRILANIQSTSNNRILVNHLEENKLVKKGDLLVQYQEGAEGVQAESY
                     ASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
                     ETIASQNAAASQTQAEIGNLISQTEAKIRDYQTAKSAIETGTSLAGQNLAYSLYQSYK
                     SQGEENPQTKVQAVAQVEAQISQLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQ
                     HLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKITASEDGVLHLNPETSDSSMVAEG
                     ALLAQLYPSLEREGKAKLTAYLSSKDVARIKVGDSVRYTTTHDAGNQLFLDSTITSID
                     ATATKTEKGNFFKIEAETNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE"
     gene            9573..10280
                     /gene="purC"
                     /locus_tag="ACL3EZ_001279"
     CDS             9573..10280
                     /gene="purC"
                     /locus_tag="ACL3EZ_001279"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004639 -
                     phosphoribosylaminoimidazolesuccinocarboxamide synthase
                     activity [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HGR0392843.1"
                     /translation="MSKQLIYSGKAKDIYTTEDENLIISTYKDQATAFNGVKKEQIAG
                     KGVLNNQISSFIFEKLNAAGVATHFVEKLSDTEQLNKKVKIIPLEVVLRNYTAGSFSK
                     RFGVDEGIALETPIVEFYYKNDDLDDPFINDEHVKFLQIADDQQIAYLKEETRRINEL
                     LKVWFAEIGLKLIDFKLEFGFDKDGKIILADEFSPDNCRLWDADGNHMDKDVFRRGLG
                     ELTDVYEIVWEKLQGLK"
     gene            10337..14062
                     /locus_tag="ACL3EZ_001280"
     CDS             10337..14062
                     /locus_tag="ACL3EZ_001280"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004642 -
                     phosphoribosylformylglycinamidine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HGR0392844.1"
                     /translation="MDKRIFVEKKADFQVKSESLVRELQHNLGLSSLKSIRIVQVYDV
                     FDLVEDLFAPAEKHIFSEQVTDHVLDEVSVQADLANYAFFAIESLPGQFDQRAASSQE
                     ALLLLGSSSDVTVNTAQLYLVNKDIDATELEAVKNYLLNPVDSRFKDITIGIAKQEFS
                     ESDKTIPKLPFFESYTAEDFARYKAEQGMAMEVDDLLFIQDYFKSIGRVPTETELKVL
                     DTYWSDHCRHTTFETELKHIDFSASKFQKQLQSTYDKYIAMREELGRSEKPQTLMDMA
                     TIFGRYERANGRLDDMEVSDEINACSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPF
                     GGAATCIGGAIRDPLSGRSYVYQAMRISGAGDITAPISETRAGKLPQQVISKTATHGY
                     SSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAPKGNVVREKPEAGDVIILLGGK
                     TGRDGVGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRNGNVTRLIKKSNDF
                     GAGGVCVAIGELADGLEIDLNKVPLKYQGLNGTEIAISESQERMAVVVRPEDVDTFVA
                     ECNKENIDAVVVATVTEKPNLVMHWNGETIVDLERRFLDTNGVRVVVDAKVVDKDVKL
                     PEERQTSAETLESDTLTVLSDLNHASQKGLQTIFDCSVGRSTVNHPLGGRYQLTPTEA
                     SVQKLPVQHGVTHTASVIAQGFNPYVAEWSPYHGAAYAVIEATARLVAAGANWSKARF
                     SYQEYFERMDKQAERFGQPVAALLGSIEAQIQLGLPSIGGKDSMSGTFEELTVPPTLV
                     AFGVTTADSRKVLSPEFKAVGENIYYIPGQALSAEIDFDLIKKNFAQFEASQADHKVT
                     SASAVKYGGVVESLALATFGNYIGAEVTLPELKTALTAQLGGFVFTSPEEIAGVEKIG
                     QTKADFTLTVNGVKLDGHKLDSAFQGTLEEVYPTEFTQAKELEEVPAVVSDVVIKAKE
                     KVEKPVVYIPVFPGTNSEYDSAKAFEKEGAEVNLVPFVTLNEEAIVKSVETMVDNIDK
                     TNILFFAGGFSAADEPDGSAKFIVNILLNEKVRVAIDSFIARGGLIIGICNGFQALVK
                     SGLLPYGNFEDANSTSPTLFYNDANQHVAKMVETRIANTNSPWLAGVQVGDIHAIPVS
                     HGEGKFVVTAEEFAELRDNGQIFSQYVDFNGKPSMDSKYNPNGSVHAIEGITSKNGQI
                     IGKMGHSERYEDGLFQNIPGNKDQHLFASAVKHFTGK"
     gene            14155..15597
                     /gene="purF"
                     /locus_tag="ACL3EZ_001281"
     CDS             14155..15597
                     /gene="purF"
                     /locus_tag="ACL3EZ_001281"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004044 - amidophosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009113 - purine nucleobase biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HGR0392845.1"
                     /translation="MTYEVKSLNEECGVFGIWGHPDAAKLTYFGLHSLQHRGQEGAGI
                     LSNDQGQLKRHRDMGLLSEVFRNPANLDKLTGAGAIGHVRYATAGEASVDNIQPFLFR
                     FHDMQFGLAHNGNLTNAASLKKELEQRGAIFSATSDSEILAHLIRRSHNPSLMGKIKE
                     ALSLVKGGFAYILLFEDKLIAALDPNGFRPLSIGKMANGAVVVSSETCAFEVIGAEWI
                     RDLKPGEIVIIDDEGIQYDSYTDDTQLAICSMEYIYFARPDSNIHGVNVHTARKRMGA
                     QLAREFKHEADIVVGVPNSSLSAAMGFAEESGLPNEMGLIKNQYTQRTFIQPTQELRE
                     QGVRMKLSAVSGVVKGKRVVMVDDSIVRGTTSRRIVQLLKEAGATEVHVAIGSPALAY
                     PCFYGIDIQTRQELIAANHTVEETRQIIGADSLTYLSIDGLIESIGIETDAPNGGLCV
                     AYFDGDYPTPLYDYEEDYRRSLEEKTSFYK"
     gene            15634..16656
                     /gene="purM"
                     /locus_tag="ACL3EZ_001282"
     CDS             15634..16656
                     /gene="purM"
                     /locus_tag="ACL3EZ_001282"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004641 -
                     phosphoribosylformylglycinamidine cyclo-ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HGR0392846.1"
                     /translation="MTNKNAYAQSGVDVEAGYEVVERIKKHVARTERAGVMGALGGFG
                     GMFDLSKTGVKEPVLISGTDGVGTKLMLAIKYDKHDTIGQDCVAMCVNDIIAAGAEPL
                     YFLDYVATGKNEPAKLEQVVAGVAEGCVQAGAALIGGETAEMPGMYGEDDYDLAGFAV
                     GVAEKSQIIDGSKVVEGDVLLGLASSGIHSNGYSLVRRVFADYTGEEVLPELEGKKLK
                     EVLLEPTRIYVKAVLPLIKEELVNGIAHITGGGFIENVPRMFADDLAAEIDESKVPVL
                     PIFKALEKYGQIKHEEMFEIFNMGVGLMLAVSPENVERVKELLDEAVYEIGRIVKKEN
                     ESVIIK"
     gene            16653..17198
                     /gene="purN"
                     /locus_tag="ACL3EZ_001283"
     CDS             16653..17198
                     /gene="purN"
                     /locus_tag="ACL3EZ_001283"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004644 - phosphoribosylglycinamide
                     formyltransferase activity [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HGR0392847.1"
                     /translation="MKKIAVFASGNGSNFQVIAEEFPVEFVFSDHRDAYVLERAKQLG
                     VLSYAFELKEFESKTDYEAALVELLEEHQIDLVCLAGYMKIVGPTLLSAYEGRIVNIH
                     PAYLPEFPGAHGIEDAWNAGVGQSGVTIHWVDSGVDTGQVIKQVRVPRLADDTIDRFE
                     ARIHEAEYRLYPEVVKALFTD"
     gene            17282..17791
                     /locus_tag="ACL3EZ_001284"
     CDS             17282..17791
                     /locus_tag="ACL3EZ_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000894002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HGR0392848.1"
                     /translation="MLESKKTTRYVFYVYLMLLTWGILFKFETNPEFIAFFLAPRYIN
                     WIPFSEPLIVDGKIVFAEMLFNLISFIPLGVCFPLIKTNLSSLRIVGTGFLISLLFEC
                     LQYILAIGITDITDLTLNTLGVCVGLLIYQIFIRVFKSQTRKWINILGMLSLGFAYLV
                     LLLLHLIGV"
     gene            17816..19363
                     /gene="purH"
                     /locus_tag="ACL3EZ_001285"
     CDS             17816..19363
                     /gene="purH"
                     /locus_tag="ACL3EZ_001285"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006146083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0003937 - IMP cyclohydrolase activity
                     [Evidence IEA];
                     GO_function: GO:0004643 -
                     phosphoribosylaminoimidazolecarboxamide formyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HGR0392849.1"
                     /translation="MTKRVLISVSDKAGIVEFAQELKKLGWEIISTGGTKVALDNAGV
                     DTIAIDDVTGFPEMMDGRVKTLHPNIHGGLLARRDLDSHLEAAKDNKIELIDLVVVNL
                     YPFKETILKPDVTYADAVENIDIGGPSMLRSAAKNHASVTVVVDPADYAVVLDELAAN
                     GETSYETRQRLAAKVFRHTAAYDALIAEYFTAQVGESKPEKLTLTYDLKQPMRYGENP
                     QQDADFYQKALPTDYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKDSPTVVALKHM
                     NPCGIGQADDIETAWDYAYESDPVSIFGGIVVLNREVDAATAEKMHGVFLEIIIAPSY
                     TDEALAILINKKKNLRILALPFNAQEASEVEAEYTGVVGGLLVQNQDVVKESPADWQV
                     VTKRQPTETEATALEFAWKAIKYVKSNGIIVTNDHMTLGVGPGQTNRVASVRLAIDQA
                     KDRLNGAVLASDAFFPFADNVEEIAKAGIKAIIQPGGSVRDQEFIEAADKYGLTMVFT
                     GVRHFRH"
     gene            19485..20747
                     /gene="purD"
                     /locus_tag="ACL3EZ_001286"
     CDS             19485..20747
                     /gene="purD"
                     /locus_tag="ACL3EZ_001286"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000772208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004637 - phosphoribosylamine-glycine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0009113 - purine nucleobase biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HGR0392850.1"
                     /translation="MKLLVVGSGGREHAIAKKLLESKDVEKVFVAPGNDGMTLDGLEL
                     VNISISEHYKLIDFAKANDIAWTFIGPDDALAAGIVDDFHAAGLKAFGPTRLAAELEW
                     SKDFAKEIMVKYGVSTAAYGTFSDFEEAKAYIEKHGAPIVVKADGLALGKGVVVAETV
                     EQAVEAAHEMLLDNKFGDSGARVVIEEFLEGEEFSLFAFVNGDKFYIMPTAQDHKRAY
                     DGDKGPNTGGMGAYAPVPHLPQSVVDTAVDTIVKPVLEGMIKEGRPYLGVLYAGLILT
                     ADGPKVIEFNARFGDPETQIILPRLTSDFAQNITDILDSKEPNIMWTDKGVTLGVVVA
                     SKGYPLDYERGVELPAKTEGDVITYYAGAKFAENSRALLSNGGRVYMLVTTADTVKEA
                     QASIYQELSQQKIEGLFYRTDIGSKAIK"
     gene            21004..21120
                     /locus_tag="ACL3EZ_001287"
     CDS             21004..21120
                     /locus_tag="ACL3EZ_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase"
                     /protein_id="HGR0392851.1"
                     /translation="MKERLDDNPIVQGNWKTLGFQFRHETPLVAAAVPHKLR"
     gene            21150..21638
                     /gene="purE"
                     /locus_tag="ACL3EZ_001288"
     CDS             21150..21638
                     /gene="purE"
                     /locus_tag="ACL3EZ_001288"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009567721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009320 - phosphoribosylaminoimidazole
                     carboxylase complex [Evidence IEA];
                     GO_function: GO:0004638 - phosphoribosylaminoimidazole
                     carboxylase activity [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HGR0392852.1"
                     /translation="MKPVISIIMGSKSDWATMQKTAEVLDRFGVAYEKKVVSAHRTPD
                     LMFKHAEEARSRGIKIIIAGAGGAAHLPGMVAAKTTLPVIGVPVKSRALSGVDSLYSI
                     VQMPGGVPVATMAIGEAGATNAALFALRLLSVEDKSIADALANFAEEQGKIAEESSNE
                     LI"
     gene            21625..22698
                     /gene="purK"
                     /locus_tag="ACL3EZ_001289"
     CDS             21625..22698
                     /gene="purK"
                     /locus_tag="ACL3EZ_001289"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000099014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004638 - phosphoribosylaminoimidazole
                     carboxylase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HGR0392853.1"
                     /translation="MSSSKTIGIIGGGQLGQMMAISAIYMGHKVIALDPAADCPASRV
                     AEIIVAPYNDVDALRQLADRCDVLTYEFENVDADGLDAVIKDGQLPQGTDLLRISQNR
                     IFEKDFLSNKAQVTVAPYKVVTSSLDLADIDLSKNYVLKTATGGYDGHGQKVIRSEAD
                     LEAAYALADSADCVLEEFVNFDLEISVIVSGNGKEVTFFPVQENIHRNNILSKTIVPA
                     RISESLVDKAKAMAVRIAEQLNLSGTLCVEMFATDDDVIVNEIAPRPHNSGHYSIEAC
                     DFSQFDTHILGVLGAPLPVIKLHAPAVMLNVLGQHVEAAEKYVTENSSAHLHMYGKIE
                     AKHNRKMGHVTLISNEPDSVGEF"
     gene            22721..25108
                     /locus_tag="ACL3EZ_001290"
     CDS             22721..25108
                     /locus_tag="ACL3EZ_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001839381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HGR0392854.1"
                     /translation="MFEKIKGINIKSGIFEDETKLELFEGNFEGTNPVQNDRASLLFG
                     RNGSGKSTIARGINQLKNGEIGTDRVSFIDKNNNNIVLSDTERKSIFVFNEHYVDQKV
                     KIAQEGLDTIVILGEQVDIDEELDRLRTQLSESQIESQDYYAEYEEYLDEKNEKSPDF
                     WKKEMTDSLKGVGNWAERDREIKGNRAASPVHNNTFQNFVDLQPILDKNELEVEFNNK
                     KARYFSIRDSAVTINNELSLPDINFDSNELSTLLSEKIEEPELNSRDKYLLTLLSDST
                     KGERHLREVKDFFEDEHQKKCPFCTQSVSEDVKVELTNGITKLLSRAVEEHQSALRGK
                     KIDEINQDFSGYEQIDPILIQSYQNSINALNAKFNEINSIIDKKIDNPYNIVELPNIS
                     FSQELSQAEHDIEKINQAIIKHNSEISGIQKLKVDLLQINNELAFYEIQDAYKKFQEK
                     TNKKAICENNYNNSSKRVKDYEKQISDLEDKKLNIDIAVDEINKSLNYIFFSKNRLAI
                     QNQNGKYYLLSRGKSVVPSRVSVGERNALALCYFFTEIIQQRELADAYSHEYFIVIDD
                     PISSFDMENKVGITSYLKYCLTRFFKGNSNTRVLLMTHDKQTIYDFDIFLKEIMESCK
                     EEEGGQKSKYKKLELVSGKLQEFKTSTHDYTELLEIVFGYALGNSTPTSESFVGNAMR
                     KILEAYGSFNYKKGIAELTTDPLIVEKIDKEYRTYFENLMYRLVLNGESHFKDPVKTL
                     SIDFFDTISDEERKKTARDLLVLLYLLDDLHVLKHLEGVSNAENRLEQWKCEILE"
     gene            25281..26579
                     /gene="purB"
                     /locus_tag="ACL3EZ_001291"
     CDS             25281..26579
                     /gene="purB"
                     /locus_tag="ACL3EZ_001291"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004018 - N6-(1,2-dicarboxyethyl)AMP
                     AMP-lyase (fumarate-forming) activity [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HGR0392855.1"
                     /translation="MINRYSRPEMANIWSEENKYRAWLEVEILSDEAWAELGEIPKED
                     VALIRKKADFDIDRILEIEQETRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLYKQANDIIRRDLENFTNIIADKAKEHKFTIMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAAGVEAGKISGAVGNFANIPPFVEEYVCDKLGIRAQEISTQVLPRDL
                     HAEYFAVLASIATSIERMATEIRGLQKSEQREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MTGLARVIRGHMITAYENVALWHERDISHSSAERIITPDTTILIDYMLNRFGNIVKNL
                     TVFPENMIRNMNSTFGLIFSQRAMLTLIEKGMTREQAYDLVQPKTAYSWDNQVDFKPL
                     LEADSEVTSRLTQEEINEIFNPIYYTKRVDDIFERLGLGD"
     gene            complement(26634..30572)
                     /gene="strH"
                     /locus_tag="ACL3EZ_001292"
     CDS             complement(26634..30572)
                     /gene="strH"
                     /locus_tag="ACL3EZ_001292"
                     /EC_number="3.2.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored beta-N-acetylhexosaminidase StrH"
                     /protein_id="HGR0392856.1"
                     /translation="MKHEKQQRFSIRKYAVGAASVLIGFAFQAQTVAADGVTPTTTEN
                     QPTIHTVSDSPQSSENRTEETPKAELQPEAPKTVETETPATDKVASLPKTEEKPQEEV
                     SSTPSDKAEVVTPTSAEKETANKKEEEASPKKEEAKEVDSKESNTDKTDKDKPAKKDE
                     AKAEADKPETETGKERAATVNEKLAKKKIVSIDAGRKYFSPEQLKEIIDKAKHYGYTD
                     LHLLVGNDGLRFMLDDMSITANGKTYASDDVKRAIEKGTNDYYNDPNGNHLTESQMTD
                     LINYAKDKGIGLIPTVNSPGHMDAILNAMKELGIQNPNFSYFGKKSARTVDLDNEQAV
                     AFTKALIDKYAAYFAKKTEIFNIGLDEYANDATDAKGWSVLQADKYYPNEGYPVKGYE
                     KFIAYANDLARIVKSHGLKPMAFNDGIYYNSDTSFGSFDKDIIVSMWTGGWGGYDVAS
                     SKLLAEKGHQILNTNDAWYYVLGRNADGQGWYNLDQGLNGIKNTPITSVPKTEGADIP
                     IIGGMVAAWADTPSARYSPSHLFKLMRHFANANAEYFAADYESAEQALNEVPKDLNRY
                     TAESVAAVKEAEKAIRSLDSNLSRAQQDTIDQAIAKLQETVNNLTLTPEAQKEEEAKR
                     EVEKLAKNKVISIDAGRKYFTLDQLKRIVDKASELGYSDVHLLLGNDGLRFLLNDMTI
                     TANGKTYASDDVKKAIIEGTKAYYDDPNGTALTQAEVTELIEYAKSKDIGLIPAINSP
                     GHMDAMLVAMEKLGIKNPQAHFDKVSKTTMDLKNEEAMNFVKALIGKYMDFFAGKTKI
                     FNFGTDEYANDATSAQGWYYLKWYQLYGKFAEYANTLAAMAKERGLQPMAFNDGFYYE
                     DKDDVQFDKDVLISYWSKGWWGYNLASPQYLASKGYKFLNTNGDWYYVIGNHKQDEAY
                     PLSKAVENSGKVPFNQLASTKYPEVDLPTVGSMLSIWADRPSAEYKEEEIFELMTAFA
                     DHNKDYFRANYNALREELAKIPTNLEGYSKESLEALDAAKTALNYNLNRNKQAELDTL
                     VANLKAALQGLKPAATHSGSLDENEVAANVETRPELITRTEEIPFEVIKKENPNLPAG
                     QENIITAGVKGERTHYISVLTENGKTTETVLDSQVTKEVINQVVEVGAPVTHKGDESG
                     LAPTTEVKPRLDIQKEEIPFTTVTRENPLLLKGKTQVITKGVNGHRSNFYSVSTSADG
                     KEVKTLVNSVVAQEAVTQIVEVGTMVTHVGDENGQAAIAEEKPRLEIPSQPAPSTAPA
                     EESKALPQDPAPVVTEKKLPETGTHDSAGLVVAGLMSTLAAYGLTKRKED"
     gene            complement(30887..31603)
                     /locus_tag="ACL3EZ_001293"
     CDS             complement(30887..31603)
                     /locus_tag="ACL3EZ_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001007200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HGR0392857.1"
                     /translation="MAIPKYQYIKDELKNKIISGQFSSGDKFYTEAELISMYDVSSIT
                     VVRALNDLAKDGYIVRQQGKGTFVSRARKHKLVEFSDIELFNAKDDKVTVLSIERGNK
                     LVYLEKLGLRGDQFYYKIERIRESNGVVYIYHTSYIPEQYINANYPNLEYYSSIYNRF
                     KLDYHIHMNDEHFEEINEIVFPTPEHAASVLGVDEQFPTVLQTKITKLESTGQVLEYS
                     ETYKRSDYYKIKFISCDRDH"
     gene            31951..33738
                     /locus_tag="ACL3EZ_001294"
     CDS             31951..33738
                     /locus_tag="ACL3EZ_001294"
                     /EC_number="3.2.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HGR0392858.1"
                     /translation="MTRFEIRDDFYLDGKSFKILSGAIHYFRIPPEDWYHSLYNLKAL
                     GFNTVETYVAWNLHEPREGEFHFEGDLDLEKFLQIAQDLGLYAIVRPSPFICAEWEFG
                     GLPAWLLTKNMRIRSSDPAYIEAVGRYYDQLLPRLVPRLLNNGGNILMMQVENEYGSY
                     GEDKAYLRAIRQLMEECGVTCPLFTSDGPWRATLKAGTLIEEDLFVTGNFGSKAPYNF
                     SQMQEFFDEHGKKWPLMCMEFWDGWFNRWKEPIITRDPKELADAVREVLEQGSINLYM
                     FHGGTNFGFMNGCSARGTLDLPQVTSYDYDALLDEEGNPTAKYLAVKKMMATHFSEYP
                     QLEPLYKESMELDAIPLVEKVSLFETLDSLSSPVESLYPQKMEELGQSYGYLLYRTET
                     NWDAEEERLRIIDGRDRAQLYVDGQWVKTQYQTEIGEDIFYQGKKKGLSRLDILIENM
                     GRVNYGHKFLADTQRKGIRTGVCKDLHFLLNWKHYPLPLDNPEKIDFSKGWTQGQPAF
                     YAYDFTVEEPKDTYLDLSEFGKGVAFVNGQNLGRFWNVGPTLSLYIPHSYLKEGANRI
                     IIFETEGQYKEEIHLTRKPTLKHIKGENL"
     gene            33735..34211
                     /locus_tag="ACL3EZ_001295"
     CDS             33735..34211
                     /locus_tag="ACL3EZ_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGR0392859.1"
                     /translation="MTIVGCRIDGRLIHGQVANLWAGKLNVSRIMVVDDEVVNNDIEK
                     SGLKLATPPGVKLSILPVEKAAANILAGKYDSQRLFIVARKPDRFLGLVEAGVPLETL
                     NVGNMSQTPETRSITRSINVVDKDVEDFHKLAEKGVKLTAQMVPNDPISDFLSLLK"
     gene            34239..35144
                     /locus_tag="ACL3EZ_001296"
     CDS             34239..35144
                     /locus_tag="ACL3EZ_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HGR0392860.1"
                     /translation="MIQWWQILLLTLYSAYQICDELTIVSSAGSPVFAGFITGLIMGD
                     VTTGLLIGGNLQLFVLGVGTFGGASRIDATSGAVLATAFSVSQGIDAPLAITTIAVPV
                     AALLTYFDVLGRMTTTFFAHRVDAAIERFDYKGIERNYLLGAIPWALSRALPVFFALA
                     FGGAFVQSVVDFVEAYKWVADGLTLAGRMLPGLGFAILLRYLPVKRNLHYLAMGFGLT
                     AMLTVLYSYVTGLGGAVAGIVGTLPAEVAEKIGFVNNFKGLSMIGISIVGIFLAVLHF
                     KNSQKVAVAAPSTPSESGEIEDDEF"
     gene            35131..35946
                     /locus_tag="ACL3EZ_001297"
     CDS             35131..35946
                     /locus_tag="ACL3EZ_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HGR0392861.1"
                     /translation="MTNSNYKLTKEDFNQINKRSLFTFQLGWNYERMQASGYLYMILP
                     QLRKMYGDGTPELKEMMKVHTQFFNTSPFFHTIIAGFDLAMEEKDGVGSKDAVNGIKT
                     GLMGPFAPLGDTIFGSLVPAIMGSVAATMAIAGQPWGIFLWIAVAVAYDIFRWKQLEF
                     AYKEGVNLINNMQSTLTALIDAASVLGVFMMGALVATVINFEISYKLPIGEKMIDFQD
                     ILNQIFPRLLPAIFTAFIFWLLGKKGMNSTKAIGIIIVLALALSALGHFALGM"
     gene            35953..36357
                     /locus_tag="ACL3EZ_001298"
     CDS             35953..36357
                     /locus_tag="ACL3EZ_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGR0392862.1"
                     /translation="MTKSLILVSHGRFCEELRGSTEMIMGPQDNIYTVALLPEDGPEE
                     FTAKFEAVIEGLDDFLVFADLLGGTPCNVVSRLIMEGRDIDLYAGMNLPMVIEFINAS
                     LTGADADYKSRAAESIVKVNDLLAGFDDDEDE"
     gene            36610..37776
                     /locus_tag="ACL3EZ_001299"
     CDS             36610..37776
                     /locus_tag="ACL3EZ_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HGR0392863.1"
                     /translation="MLHYTKEDLLELGAEITTREIYQQPDVWREAFEFYQAKREEIAA
                     FLQEIADKHDYIKVILTGAGTSAYVGDTLLPYFKEVYDERKWNFNAIATTDIVANPAT
                     YLKKDVATVLVSFARSGNSPESLATVDLAKSLVDELYQVTITCAADGKLALQAHGDDR
                     NLLLLQPAVSNDAGFAMTSSFTSMMLTTLLVFDPTEFAVKSERFEVVSSLARKVLDKA
                     EDVKELVDLDFNRVIYLGAGPFFGLAHEAQLKILELTAGQVATMYESPVGFRHGPKSL
                     INDNTVVLVFGTTTDYTRKYDLDLVREVAGDQIARRVVLLSDQAFGLENVKEVALGCG
                     GVLNDIYRVFPYIVYAQLFALLTSLKVENKPDTPSPTGTVNRVVQGVIIHEYQK"
     gene            37892..38929
                     /locus_tag="ACL3EZ_001300"
     CDS             37892..38929
                     /locus_tag="ACL3EZ_001300"
                     /EC_number="5.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase family protein"
                     /protein_id="HGR0392864.1"
                     /translation="MKAYTERVFGNVEGEDVLAYRFETDGGYQLEVMTYGATILRYVA
                     PDKAGNFANVILGFDDFDSYVGNSPKHGASVGPVAGRIAGATFELNGKTYDLEVNNAS
                     NCNHSGSTGWDSSLFEVEEVSDHGLTLYTERTDGTGGFPGNLKIWISYHLEETGAYEI
                     SYKVTTDQDTLVNPTNHSYFNLSGDFTQTIDRHVFQLNTEGIYSIAPDGVPAKTPEAN
                     RDVVKHVYNGTLLKDIFAEEDEQIQLASGLDHPFALPAGHDNAGFLYDQNSGRFLLFK
                     TEAPCFVVYTANFVDESVIIGGQPMLQHNGIALEAQALPDAIHSDLKGQVILKAGQTF
                     TSKTRYELVVK"
     gene            39137..39991
                     /locus_tag="ACL3EZ_001301"
     CDS             39137..39991
                     /locus_tag="ACL3EZ_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HGR0392865.1"
                     /translation="MTYEYKSHIYLAETALNVKDLASQTAFYQQVIGLEILSQTETES
                     ILGLGGKVLVQLIQAQESGEVREYYGLYHLAILLPTRKALADVLKHLTDLQIPLVGGA
                     DHGYSEAIYLEDLEGNGIELYRDKPVSTWDIREDGRIIGVTEALAAQDIYELGERVEP
                     FILAEGTRMGHIHLSVKDSRKSSQFYQKVLGLENKFSVPGASWIAAGDYHHHLAVNEW
                     GGKGLASRKQGLPGLAYYVIEVAHKKELLTIAQRAQEVDAPIKWMTSIQLEITDSDGI
                     VTRIRLAR"
     gene            40128..40385
                     /locus_tag="ACL3EZ_001302"
     CDS             40128..40385
                     /locus_tag="ACL3EZ_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HGR0392866.1"
                     /translation="MTNSKYITCLKRSEGQLCGIQKMIEGDRDCADIVTQLTAVKSSV
                     ERVIEMIITENLTECINQPLDDSEAQKERLEKAIRYLIKRK"
     gene            complement(40427..>40650)
                     /locus_tag="ACL3EZ_001303"
     CDS             complement(40427..>40650)
                     /locus_tag="ACL3EZ_001303"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0392867.1"
                     /translation="YGKVKLTWFEEIFEEYKSLHNKTHITKVLMNCTPKVRQKKSNFW
                     GSVHSTPDTMRFFNFRDFLQLLLTHIKLF"
BASE COUNT        11844 a         7303 c         9074 g        12429 t
ORIGIN      
        1 aagacgtttc gatgccaatt caagatttgg atgaaaaaaa ttaatagata ctgttatact
       61 aaacttgtca agtttgtaac aagacaaata ttaaaaataa aaaagaggta ttcgttatga
      121 atacaaaaac gatgtcacaa tttgaaatta tggatactga gatgcttgct tgcgttgaag
      181 gtggcggatg caattgggga gattttgcca aagcaggtgt tggaggagga gcagcacgag
      241 gtcttcagct aggaattaaa acaagaacat ggcaaggtgc agcaactggt gctgtgggag
      301 gagctatact tggaggtgtg gcctatgcag cgacatgttg gtggtaatta tggattttaa
      361 aagttttatt attggtttag tagttggtat atttggtcct tatatggatg atttaattag
      421 aaaaaaattt ttaaagtctt cggagaagaa aacagaaaaa tctgttaaaa aataatcaaa
      481 actataaatg atgaatctga atcaaaatta ttttgcgcat gtaaatagga gtcttatagt
      541 aacgagtcaa aaaaggagta actatgaatc gtaatttaga acggtgttat ctattctgac
      601 taggaataga tcataccaga ggtggcttag aaatagcggg gacattagaa attgaaggaa
      661 ctttaaatag gatgtcgtaa atgttgctat caatgattta tttgtcccaa gcttgcctag
      721 ggtgtcagta aaaaatcatt ttcctttcat atcatatttt tagtaggtag gatgtttgtt
      781 ctgtctattt tttgccaaaa aaagtgcagt tgaagtgttt atttggagtt ttatatatat
      841 tttcgataaa ataggtgtag aaattaggaa agttgaagaa aagaaatgaa gaaggtttta
      901 aaatattttt tagtatttgt ttttctattt ttgatgaata ttttcatctt taagatacta
      961 gcaaccctgg gatttcagct gataatgagt gaaaagagtt atattgttct accgctgttt
     1021 tcgcttatcg ttttatatat gattgacaaa agaattagga agaaaaagaa atctttgtaa
     1081 tcaacttaag gagtattact atggatgagt tgaaacgtga aattggttat aaaatcaaaa
     1141 ctattaggcg atcttgtgga aaaactcaga tagatatttg tggtgatgaa tcagagttga
     1201 cgattcgtca gctagcacgt attgaaaatg ggcaagcttt agcaacactt cctaaattat
     1261 tattgattgc ggataaactt ggagtatcat tacagaatat tgtggatgtt aaggttatag
     1321 agattccaaa aggattccta aaactcaaag atgagctgat tcattctcaa acctacgctg
     1381 ataagggaag aatcgaatga aaagaagcta tacttgagga aatatatgaa aactattatg
     1441 agaatttgcc tgaggaagag cagttaattg tggatgtgac acaagctcgt tttgatattt
     1501 atggtagttc agatgtgacc tacggtttag ggttagtgga agaatatttc cagcagttat
     1561 taaaaaagaa atatttttct gtaaatgatt tgttgattat tgaattgtat ttcttttgtt
     1621 gtgctatggg attagaagat aaagaacatt ttgaggagtt agctcaaaaa gtattgctat
     1681 gttcagaata tgaagataag gctagcctag ttcaaatgga aaaagttctt ctgagcctat
     1741 ttatccaaat tcagacagaa gatagtctga tatatattca aacatttgag aaaattattg
     1801 ctaaaacaag acatgttttt taccgacctc atctattttt gctaaaggca aaatatgctt
     1861 tatttgtaga caagaatatt ttagaggcag aaagtttcta tgaaaaggcg atttctctag
     1921 cagaattgct agacgatcag gtattagttc agagaatttt agcagaaaaa cagatagatt
     1981 tcccaacaac ctgacttcta agtcatgttg tttttttcat gtttttgcta tactaaacct
     2041 ataaagaaaa cgttctcaaa aagaaaggag gtttattatg gttggaacgt tatttgtcct
     2101 tttaagtata ggaatttggt tctatctata atatcgggta gagattaatg gaacaaggta
     2161 ttcttatatt ggattaaagg aatgtcctac attagtatag aggatgaaac tcaattttca
     2221 atgatataga agagttattt ggagattgtg agggttgagt atgtttattt atgatgtagg
     2281 aagtgtaaac taaaaagaag gtagtaatcg tataaaagtt aaatagacat tatcttttat
     2341 tgagtcttag tgatataaaa gtaatttgat aatctaggaa aatgtagtag taatttattt
     2401 attatagata tgttaataaa agtagtataa aatatagacg aacatttgaa gagagttagg
     2461 aatacaacat gtgcgaatta actctcaata aaacatacat aatatacaaa aggagtacac
     2521 taaaatgaaa tctaaaagaa tggaatttca taataaattt cttattgttt cagcaatgtt
     2581 agcagtcatt agttggttaa gcttaggtgt tgtttctttt cctatgttgg ctgggacatt
     2641 aggaatttcg acaaaagctg ctgctactgt agtcaatttg attagtgctt atagtacagt
     2701 tacagcagta atttcaattg taggtgcaat cacaggagta ggttctattg gttcgggtat
     2761 tgcagcaaca gttctttata tattgaaaaa gaaaggtgct gctaaagcag ctctatggta
     2821 gaactagatg aaaatacttt ctaaaaaaga atgtgaaagt attttaggtt atcttaattt
     2881 tattgggata acccttttgt tttttgttat cataagtttg tcaatctatt ttaaaagcta
     2941 tcttcctttt caagggaaat tatttttact ttttttggta gtagattacg ctactttgaa
     3001 tcgttataat atgaaactgc ctatccaaag taaaaaaata aatactttct atataaggaa
     3061 aaactatatt tttctctatc ttcttgccat tgtcaagaaa tattattctt tccaaatttt
     3121 acaatcattc atttatttat ttattttgta ttttctagat attattggat atttttattt
     3181 atccattact ctttgtttga tagctattca aattatttct ttaattctac ctagtttgtt
     3241 ttcaattata agtaaattgt tcttattttt atctatagga ctattgtcta tagaacaagg
     3301 acaagttgta atttatgtca tactactcaa ttattttatt ttagtcatgg ggatattaga
     3361 taatcatgcg agtaatttct attttaaaag cagtcgaatg agtcaaaaaa gatttcgtag
     3421 cagtctattt atattgcttc gtttttgttg gttaaataaa gggttaactt tttcttttat
     3481 tttgattagt attcttcttt cctatctatt ttggtatatg atgacgatgt tatcaattga
     3541 tgacacaaaa ataccaatat tatttcttta tacctcaata tatattacat taatggaggc
     3601 aataataggg aatcataaat cctcaattgg ggtagatcta gctttacttc aattatctgc
     3661 tcttaatcat tctaaaatga atttcttttt taagaatgca caactaatga tgttgacgca
     3721 tttaatctct ttcttacaat tttcattgtt gttatgtttg attccggtga caagttatag
     3781 taatgatata aaaagtattt tgttgaattt gttattgatt ccattcaatt attttatagc
     3841 ctatgtctat tataagaaag ctctattttt aattaaaggt acagttagtt tattgagatg
     3901 gagttttctg gttttatatt gttttctgat aatatttgta attttagtag ggggcattag
     3961 atgagaaaaa gtggttttct gatttactat gtgttatttt gtatagtctg ttttttacta
     4021 ggtttacttt taagctttat attaaaaaat gagacttttg ctactatacc tccgaaactg
     4081 gaattacaat ttacattgac agttttacag gcaaattcta caaatttttt gctatatcta
     4141 ttctgttttc cgatttcgcc cttattgcaa ctttttgatt tgctatcttt aggaatacaa
     4201 ttgggtatat ctggtcagat gattggaata gtagctacaa taaaaggaat attacctcat
     4261 gctcttattg aaataccgaa ttttatttgg tatcaaggta tgagtcagta tcttttatac
     4321 cgattattga aggatagggg aattaaaaat atacttattt atataaaaag taatttaaaa
     4381 tggtatatca tttcttatct tttattaatt ttagcagcgt tgatagaggg aattaaatta
     4441 tgaaaattga aaatgaatct aaaagttatg ataaatgtat attgaaaaat atatcactag
     4501 agattgataa gggaatttac agagttgaag gagagaatgg ttcaggaaag agcacccttc
     4561 tacaactttt agctgggcta gagacttttg atagtggttt aaagaattgt gtctccaaag
     4621 atgtactata ccttgatacc aatcagcttg gggttgttcc atttactata gaagaaaatt
     4681 tgcagttgtt gtgtgattct tttcaaatcc atctatcatt tgaggataaa gaacaaatta
     4741 atactttttt tgataataaa atcggagata actatatgac agcatctact ggaacaaaat
     4801 tcaaattagg cttatcctta atttttgcta aaaattggga ttatattttt attgatgaga
     4861 ctttatcaac agtggatgca agaagtattg atatgattgc taaacgctta atttccatga
     4921 aagaaagctc tactattata tatgtatctc ataatttatt gaatcaagaa ttgattagca
     4981 aatctcaaag gattttaata gaggaaggac gggtttatga aatttcaaac aaataatagt
     5041 ttatacaaat taatgaatct gattatttat ctttttcttt tatatttgtt tattgattta
     5101 ctgatgaagt cgggaatttt agatgaacaa attgataaat tatctgaact atctaatctt
     5161 tttacaatta aaatagaaac aatattgaca gtgatttctg ttgttttcac atttatagca
     5221 actcttattg aatatggatt ttctctcttt ctgattacat tattttttga taagaataag
     5281 aggaactttg gagatattct tttatctaaa aatataacct taagttttag cattttactt
     5341 tgttatttat ttaatccatc ggatataaag tttgcctatt tcagcgtatt gacagtatta
     5401 ctaattggga taacaaatta tgcgagattt aaaaatttaa gattgacagt agtgttttct
     5461 gtaccatttt tatttaatgc tataatgtct attataaata gtttttagaa atactaaaat
     5521 ttttttcttt acttaataat gatatgaaat catttcggtt ttgttaactt gtaattctta
     5581 tattttctag gtagaacgtt tgttctgcct atttttttat ccaaaaagtg cagttgggag
     5641 ggagataggc tcatttggga aggaagtcca gtttttgttt agtgattggg gtaagatagt
     5701 tgttatcaga tgagtttata ctcttcgaaa atcaaattca aaccacgtca acgtcgcctt
     5761 gccgtatata tgtgactgac ttcgtcagtc ctatctacaa cctcaaaaca gtgttttgag
     5821 cagcctgcgg ctagtttcct agtttgctct ttgattttca ttgagtatta gggaaaagga
     5881 gatgaatatg aaatttggga aacgtcacta tcgtccgcaa gtggatcaga tggactgcgg
     5941 tgtagcttca ttagccatgg tttttggcta ctatggtagt tattattttt tggctcactt
     6001 gcgagaattg gctaagacga ccatggatgg gacgacggct ttgggcttgg tcaaggtggc
     6061 agaggagatt ggttttgaga cgcgagccat taaggcggat atgacgcttt ttgacttgcc
     6121 ggatttgact tttccttttg ttgcccatgt gcttaaggaa gggaaattgc tccactacta
     6181 tgtggtgact gggcaggata aggatagcat tcatattgcc gatccagatc ccggggtgaa
     6241 gttgactaaa ctgccacgtg agcgttttga ggaagaatgg acaggagtga ctctttttat
     6301 ggcacctagt ccagactata agcctcataa ggaacaaaaa aatggtctgc tctcttttat
     6361 ccctatatta gtgaagcagc gtggcttgat tgccaatatc gttttggcaa cactcttggt
     6421 aaccgtgatt aacattgtgg gttcttatta tctgcagtct atcattgata cctatgtgcc
     6481 agatcagatg cgttcgacac tagggattat ttctattggg ctagtcatcg tctacatcct
     6541 ccagcaaatc ttgtcttacg ctcaggagta tctcttgctt gttttggggc aacgcttgtc
     6601 gattgacgtg attttgtcct atatcaagca tgtttttcac ctccctatgt ccttctttgc
     6661 gacacgcagg acaggggaga tcgtgtctcg ttttacagat gctaacagta tcatcgatgc
     6721 gctggcttcg accatccttt cgattttcct agatgtgtca acggttgtca ttatttccct
     6781 tgttctattt tcacaaaata ccaatctctt tttcatgact ttattggcgc ttcctatcta
     6841 cacagtgatt atctttgcct ttatgaagcc gtttgaaaag atgaatcggg ataccatgga
     6901 agccaatgcg gttctgtctt cttctatcat tgaggacatc aacggtattg agactatcaa
     6961 gtccttgacc agtgaaagtc agcgttacca aaaaattgac aaggaatttg tggattatct
     7021 gaagaaatcc tttacctata gtcgagcaga gagtcagcaa aaggctctga aaaaggttgc
     7081 ccatctcttg cttaatgtcg gcattctctg gatgggggct gttctggtca tggatggcaa
     7141 gatgagtttg gggcagttga ttacctataa taccttgctt gtttacttta ccaatccttt
     7201 ggaaaatatc atcaatctgc aaaccaagct tcagacagcg caggttgcca ataaccgtct
     7261 aaatgaagtg tatctagtag cttctgagtt tgaggagaag aaaacagttg aggatttgag
     7321 cttgatgaag ggagatatga ccttcaagca ggttcattac aagtatggct atggtcgaga
     7381 cgtcttgtcg gatatcaatt taaccgttcc ccaagggtct aaggtggctt ttgtggggat
     7441 ttcagggtca ggtaagacga ctttggccaa gatgatggtt aatttttacg acccaagtca
     7501 aggggagatt agtctgggtg gtgtcaatct caatcagatt gataaaaaag ccctgcgcca
     7561 gtacatcaac tatctgcctc aacagcccta tgtctttaac ggaacgattt tggagaatct
     7621 tcttttggga gccaaggagg ggacgacaca ggaagatatc ttacgggcgg tcgaattggc
     7681 agagattcga gaggatatcg agcgcatgcc actgaattat cagacagaat tgacttcgga
     7741 tggggcaggg atttcaggtg gtcaacgtca gagaatcgct ttggcgcgtg ctctcttgac
     7801 agatgcgccg gtcttgattt tggatgaggc gactagcagt ttggatattt tgacagagaa
     7861 gcggattgtc gataatctca ttgctttgga caagaccttg attttcattg ctcaccgctt
     7921 gactattgct gagcggacag agaaggtggt tgtcttggat cagggcaaga ttgtcgaaga
     7981 aggaaagcat gctgatttgc ttgcacaggg aggcttttac gcccatttgg tcaatagcta
     8041 gaaagaggag aggatgaaac cagaattttt agaaagtgcg gagttttata atcgtcgtta
     8101 ccataatttt tccagtagtg tgattgtacc catggccctt ctgctcgtgt ttttacttgg
     8161 ctttgcaact gttgcagaga aggagatgag tttgtccact agagctactg tcgaacccag
     8221 tcgtatcctt gcaaatatcc agtcaactag caacaatcgt attcttgtca atcatttgga
     8281 agaaaataag ctggttaaga agggggatct tttggttcaa taccaagaag gggcagaggg
     8341 tgtccaagcg gagtcctatg ccagtcagtt ggacatgcta aaggatcaaa aaaagcaatt
     8401 ggagtatctg caaaagagcc tgcaagaagg ggagaaccac tttccagagg aggataagtt
     8461 tggctaccaa gccacctttc gcgactacat cagtcaagca ggcagtctta gggctagtac
     8521 atcgcaacaa aatgagacca tcgcgtccca gaatgcagca gctagccaaa cccaagccga
     8581 aatcggcaac ctcatcagtc aaacagaggc taaaattcgc gattaccaga cagctaagtc
     8641 agctattgaa acaggtactt ccttggccgg tcagaatcta gcctactctc tttaccagtc
     8701 ctacaagtct cagggcgagg aaaatcccca aactaaggtt caggcagttg cacaggttga
     8761 agcacagatt tctcagttag aatctagtct tgctacttac cgtgtccagt atgcaggttc
     8821 aggtacccag caagcctatg cgtcagggtt aagcagtcaa ttggaatccc ttaaatccca
     8881 acacttggca aaggttggtc aggaattgac ccttctagcc cagaaaatct tggaggcaga
     8941 gtcaggtaag aaggtacagg gaaatctttt agacaagggg aaaattacgg caagtgagga
     9001 tggggtgctt catcttaatc ctgagaccag tgattctagc atggttgcag aaggtgccct
     9061 actagcccaa ctttatccat ctttggaaag agaagggaaa gccaaactca cagcctatct
     9121 aagttcaaaa gatgtagcaa gaatcaaggt cggtgattct gttcgctata ctacgactca
     9181 tgatgccggg aatcaacttt ttctagattc tactattaca agtattgatg cgacagctac
     9241 taagactgag aaagggaatt tctttaaaat cgaggcggag actaatctaa cttcggagca
     9301 ggctgaaaaa cttaggtacg gggtggaagg ccgtctacag atgattacgg gcaagaaaag
     9361 ttatctacgt tattatttgg atcaattttt gaacaaagag taatgttcgt gtttttagag
     9421 ttaaataatt tttaaactgt gagaaagatt cttcttgcag ttttttcttt acaatttttg
     9481 aaaaacatct gctatttatt cggttaaatt cttgtgtttt ttggtttttt gtggtaaaat
     9541 gtgctcaagt aatacgaaag gcgaacttta aaatgtcaaa acaattgatc tattcgggaa
     9601 aagctaaaga tatctataca actgaggatg aaaatcttat tatttcaact tacaaggacc
     9661 aggcgactgc tttcaatggt gtcaagaagg agcagattgc aggtaaggga gtcttgaata
     9721 atcagatttc atcttttatt tttgagaaat taaatgcggc tggtgtggcg actcactttg
     9781 tggagaaact ttcagacacg gaacaactca ataaaaaggt taagattatt cctttggaag
     9841 tcgtgctccg caactatact gctggttcct tttcaaaacg ttttggtgtg gatgagggaa
     9901 tcgccttgga gactccgatt gtcgaatttt actacaaaaa tgatgatttg gatgatccat
     9961 ttatcaatga tgagcatgtg aaattcctac agattgcgga tgaccagcag attgcctact
    10021 tgaaggaaga aacgcgtcgt atcaatgaac tattgaaagt ctggtttgct gagattgggc
    10081 ttaaattgat tgactttaag ctagagttcg gttttgacaa ggatggcaag attatcttgg
    10141 cagacgaatt ttcaccagat aactgccgct tgtgggatgc tgatggcaac cacatggata
    10201 aggatgtttt ccgtagagga ttgggagaac taaccgacgt ttatgagatt gtttgggaaa
    10261 agttgcaggg tttaaaataa caacctcaag gctgtttggg aatattgcaa gagctgaaat
    10321 aaaggaataa gaattgatgg ataaacgtat ttttgttgaa aaaaaggctg attttcaggt
    10381 caagtcagag agtttggtta gagagctcca gcacaacttg ggactgtcaa gcttgaaaag
    10441 tattcgtatt gtgcaagtat atgatgtatt tgacttggtt gaggacttgt ttgcacctgc
    10501 agagaagcac attttctctg agcaggtaac cgaccatgtt ttagatgaag tatctgtgca
    10561 ggcggatctt gctaactatg ctttctttgc cattgaaagt ctaccagggc agtttgacca
    10621 gcgtgcagct tcgtcacagg aagccttgct tttgttggga agttcgagtg acgtgacagt
    10681 caacacagcc caactttact tggtgaataa agatattgat gcgactgagt tggaagctgt
    10741 caaaaactac ctgctcaatc cagttgattc tcgtttcaag gatatcacga tagggattgc
    10801 caagcaggag ttttcagagt cagacaagac cattccaaaa ttgcctttct ttgaaagcta
    10861 tacagcagaa gactttgctc gctacaaggc cgaacaaggg atggccatgg aagtggatga
    10921 tttgctcttt atccaagact actttaagtc aatcgggcgc gtgccaactg agactgaact
    10981 caaggttttg gacacttact ggtctgacca ctgccgtcat acgacttttg agacagagtt
    11041 gaaacacatc gacttttcag cttctaaatt tcaaaagcaa ttgcagtcaa cctatgacaa
    11101 gtatattgcc atgcgcgagg aattaggtcg gtctgaaaaa ccacaaacct tgatggatat
    11161 ggcgactatt ttcggtcgtt atgagcgtgc taatggacga ttggatgata tggaagtctc
    11221 tgacgaaatc aatgcctgct cagttgaaat tgaagtggac gttgatggtg tcaaggaacc
    11281 ttggctcctc atgtttaaaa acgaaaccca caaccatcca acagaaattg agccatttgg
    11341 tggagcggct acctgtatcg gtggagctat tcgtgatccg ttgtcaggcc gttcctatgt
    11401 ttaccaagcc atgcgtattt caggtgctgg tgatattaca gcaccgattt cggaaactcg
    11461 tgctgggaaa ttgccacaac aagtcatttc taaaacagca actcatggtt attcttcata
    11521 tggtaaccag attgggcttg ccacaaccta cgttcgtgaa tacttccacc caggctttgt
    11581 agctaaacgt atggaacttg gtgccgttgt tggtgcggct cccaagggca atgttgtccg
    11641 tgaaaaacct gaagcaggtg atgtgatcat ccttctcgga ggtaaaacag gtcgtgatgg
    11701 tgtcggtggt gcgacgggct cttctaaggt tcaaacagtt gagtctgtag agactgctgg
    11761 tgctgaggtt caaaaaggaa atgccatcga agaacgcaag attcagcgcc tcttccgtaa
    11821 tggcaatgtc actcgtctga tcaagaagtc caatgacttt ggggcaggcg gtgtctgtgt
    11881 ggctatcggt gaattggcag acggtcttga aatcgacctc aacaaggtgc ctcttaaata
    11941 ccagggcttg aatggtacag aaattgccat ctctgaatca caagaacgga tggcggtcgt
    12001 ggttcgtcct gaagatgtgg ataccttcgt tgccgaatgt aacaaagaaa atattgatgc
    12061 tgttgtggtg gcgacagtaa ctgaaaaacc aaatcttgtc atgcactgga atggtgagac
    12121 aatcgttgac ttggagcgtc gtttccttga caccaatggt gtgcgcgtgg ttgtcgatgc
    12181 caaagttgtg gacaaggatg tcaaactccc agaagagcgt caaacatctg ctgaaacact
    12241 ggaatcagat acccttacgg ttctatctga cctcaaccat gcaagtcaaa aaggattaca
    12301 gactatcttt gactgctctg ttggacgctc aacggttaat cacccacttg gtggtcgtta
    12361 ccaactcaca ccaactgagg catctgtgca gaaattgcca gttcaacacg gtgtgactca
    12421 tactgcgtcg gtcattgctc aaggtttcaa cccatatgta gctgaatggt ctccatacca
    12481 cggtgctgct tatgcggtta tcgaagcaac tgctcgtttg gtggctgctg gtgccaactg
    12541 gtctaaggct cgtttctctt accaagaata tttcgagcgg atggacaagc aagcagagcg
    12601 ttttggtcag ccagtagccg cccttctagg ctctattgaa gcacaaattc agcttggctt
    12661 gccatctatc ggtggtaagg actccatgtc tggtaccttt gaagaattga ccgttccgcc
    12721 aaccttggtt gcctttgggg tgacgacggc agatagccgt aaggtgctct ctccagaatt
    12781 taaagctgtt ggggaaaata tctactacat cccaggtcaa gccctctctg cagagattga
    12841 ttttgacttg attaagaaaa attttgctca gtttgaagca agccaagctg accataaagt
    12901 gacatctgca tcagctgtca aatacggtgg tgtagttgaa agtttggctc ttgctacctt
    12961 tggaaactat attggtgcag aggtgacctt gcctgaactt aaaacagctt tgacagctca
    13021 attaggcggc tttgtcttca catctcctga agaaattgct ggagtagaga agattggaca
    13081 aacgaaagca gactttacac tgactgtcaa cggtgtgaag ctagatggac acaagcttga
    13141 cagtgcattt caagggacat tggaagaagt ttacccaaca gaatttaccc aagcgaaaga
    13201 actagaagaa gtaccagctg tggtatcaga tgttgtgatt aaagccaaag aaaaggttga
    13261 aaaacctgtg gtttacatcc cagtctttcc aggaaccaac tcagaatatg attcagctaa
    13321 ggccttcgaa aaagaaggtg cagaggtcaa tttggtgcca ttcgtgacct tgaatgaaga
    13381 agctattgtc aagtcagttg aaactatggt tgacaatatc gacaagacta atattctctt
    13441 ctttgccggt ggattctcgg ctgcggatga accagatggt tcagctaagt ttatcgtcaa
    13501 tatcctgctt aatgaaaaag tgcgtgtggc tattgatagc tttatcgccc gtggtggctt
    13561 gattatcggt atttgtaatg gattccaagc cttagtcaaa tcgggtctcc taccatacgg
    13621 aaactttgaa gatgctaaca gtactagtcc aaccctcttc tacaatgatg ccaaccaaca
    13681 cgtggccaag atggtggaaa ctcgtattgc caataccaac tcaccatggt tggctggtgt
    13741 gcaagtgggc gatatccacg ctattcctgt ttcgcacggt gaagggaagt ttgtcgtgac
    13801 ggctgaggaa tttgcagagc tccgtgacaa tggacaaatt ttcagccaat acgttgactt
    13861 taacggtaaa ccaagtatgg attctaagta caatccgaat ggttctgtcc atgccatcga
    13921 aggaattacc agcaagaatg gtcaaatcat cggtaagatg ggccactcag aacgttatga
    13981 ggatggtctt ttccaaaata tcccaggcaa taaagaccaa cacctgttcg catcagcggt
    14041 taaacatttc actggaaaat aagacttaca gattttctaa tagatagtat cagtaatgta
    14101 aaagtcatgt aaatctagct cttgatgatt acaaatgaaa attaggtata aaaaatgaca
    14161 tacgaagtaa aatctcttaa tgaagaatgt ggtgttttcg gtatttgggg acatccagat
    14221 gctgctaagt tgacctattt tggactccac agtcttcaac accgtggtca ggagggggca
    14281 ggaatcctct ccaatgatca aggacaactg aagcgccatc gtgacatggg gcttttatca
    14341 gaagttttca gaaatccagc caatttggat aaattgacag gagctggtgc gattgggcat
    14401 gtgcgttatg cgactgctgg cgaagcttct gttgataaca tccagccctt cctcttccgt
    14461 tttcacgata tgcagtttgg cttggctcat aatggaaatc tgaccaatgc agcctctctc
    14521 aagaaagaac tggaacaaag aggagcaatt ttcagcgcga cttcggactc tgaaatcttg
    14581 gctcacctca ttcgtcgcag tcataatcct agcctgatgg gcaaaatcaa ggaagcgctc
    14641 agccttgtca aaggtggttt tgcctatatc ttgctgtttg aggacaagtt gattgcggct
    14701 cttgacccta atggctttcg tccgctttct atcgggaaaa tggccaacgg agcggtggtt
    14761 gtttcctctg aaacctgtgc ttttgaggtc attggtgccg agtggattcg tgatttgaag
    14821 ccaggtgaga ttgtgatcat tgatgacgag ggcattcagt atgacagcta tacagatgat
    14881 actcagttgg cgatttgttc tatggagtat atctactttg ctcgccctga ttctaatatc
    14941 cacggtgtca atgtccatac ggcacgtaag agaatgggag cgcaattggc gcgagaattt
    15001 aagcatgagg cagatattgt agttggtgtg cccaattctt ccctaagcgc ggctatggga
    15061 tttgcggaag aatcaggctt accaaatgaa atgggtctga tcaaaaacca atacacccag
    15121 cgaactttta tccaaccgac tcaagaattg cgggagcaag gagtgcggat gaaactgtct
    15181 gctgtttcgg gtgttgtcaa aggcaaacgt gtggtcatgg tggatgattc cattgtacgt
    15241 ggaacaacct ctcgtcgtat cgttcagctc ttgaaagaag cgggtgcgac tgaggttcac
    15301 gttgccattg gaagtcctgc actagcgtat ccatgtttct acgggattga tatccagacc
    15361 cgtcaggagc tgattgcagc caatcatacg gtcgaagaaa ctcgccaaat cattggtgcg
    15421 gacagtctga cttatctttc aattgatggc ttgattgagt cgattggtat cgaaacagat
    15481 gcgccgaacg gtggtctctg tgtcgcttac tttgacggtg actacccaac gcctctctat
    15541 gactacgaag aagactatcg tagaagtttg gaagaaaaga ccagttttta caagtaggcg
    15601 acagattctc cattaaagaa aaggaaaaaa caaatgacaa ataaaaatgc atatgcccag
    15661 tcgggtgtgg atgttgaagc gggttatgaa gttgttgaac ggattaaaaa gcacgtggcc
    15721 cgtacggagc gtgcaggtgt catgggagct cttggtggct ttggtggtat gtttgacctt
    15781 tccaagactg gggttaaaga acccgtcttg atttcaggga ctgacggtgt cggaaccaag
    15841 ctcatgttgg ctatcaagta cgacaagcac gataccatcg ggcaggactg tgtggccatg
    15901 tgtgtcaacg acatcattgc tgcaggtgcg gaacccctct attttctcga ctacgtagcg
    15961 acagggaaga atgaaccagc taagctagaa caagtggttg ctggtgtggc agaaggttgt
    16021 gtgcaggctg gtgctgccct catcggtggg gaaacggctg aaatgccggg catgtacggc
    16081 gaagacgact atgacttggc tggttttgcg gtcggtgtgg ctgaaaaatc tcaaatcatt
    16141 gacggttcaa aggtggtaga gggagatgtt cttctcggac ttgcttcaag tgggattcac
    16201 tcaaatggtt actctttggt tcgtcgtgtc tttgcggatt acacaggtga ggaagtccta
    16261 ccagaattgg aaggcaagaa acttaaggaa gttctacttg agccgactcg tatctatgtc
    16321 aaggctgtct tgccgctcat caaagaagag ttggtcaacg gcattgccca catcacaggt
    16381 ggtggcttta tcgaaaatgt ccctcgtatg tttgcagatg acctagctgc tgaaattgat
    16441 gaaagcaaag ttccagtgct tccaattttc aaagcccttg aaaaatatgg tcagattaaa
    16501 cacgaagaaa tgtttgaaat cttcaatatg ggtgtgggac ttatgttggc ggtcagccct
    16561 gaaaatgtag agcgtgtaaa agaattgttg gatgaagcag tctatgaaat tggtcgcatc
    16621 gtcaagaaag aaaacgaaag tgtcattatc aaatgaaaaa aatagcggtt tttgcctctg
    16681 gtaatggctc aaattttcag gtgattgccg aagaatttcc agtggagttt gtcttttcag
    16741 accatcgtga tgcctatgtg cttgagcgtg caaagcagct cggcgttctg tcctatgctt
    16801 ttgaactcaa ggagtttgag agcaagacag actacgaagc agcccttgtc gaactcttgg
    16861 aagaacacca gattgacttg gtttgcctag caggctacat gaaaatcgtt ggaccaacct
    16921 tattgtcggc ttatgaaggt cggattgtca acattcatcc agcctacttg ccagaatttc
    16981 caggagctca tgggattgag gatgcttgga atgctggcgt gggtcagtct ggtgtgacca
    17041 ttcactgggt ggattcgggt gtggatacag gccaggtcat caaacaggtt cgtgtgccac
    17101 gactagctga tgataccatt gacagatttg aagctcgcat ccatgaagca gagtacaggt
    17161 tgtatccgga agtagtgaag gctctattta cagattgact ttttgatgat tcatatgata
    17221 tctttgattt taaattggag tcagtgtttg ttgaagacgg cttcaaacgg aggtatttgt
    17281 aatgttagaa tctaaaaaaa caactcgata tgtattttat gtctatctga tgttattaac
    17341 ttggggaatc ttatttaagt ttgaaacaaa tcctgaattt atagcatttt tcttagctcc
    17401 aaggtatatc aattggattc cattttcaga accactaata gtcgatggaa aaattgtttt
    17461 tgctgaaatg ttatttaatc tgatttcctt tattccatta ggtgtttgtt tccctttgat
    17521 aaaaactaat ttatctagtt taagaatagt cgggacaggt ttcttgatta gtttattgtt
    17581 tgagtgctta cagtatattt tagcaatagg tataacagat ataacggatt tgactttaaa
    17641 tacgctaggt gtctgtgtag gcttactgat ttatcaaatt tttataagag tgttcaaatc
    17701 acagactaga aaatggatca atatcttagg tatgcttagc cttggttttg cttatcttgt
    17761 tttactgtta ctgcatttaa ttggtgttta actaatgatt aaaaaggaga atataatgac
    17821 taaacgcgtc ttaatcagcg tctcagacaa agcgggcatt gttgaatttg cccaagaact
    17881 caaaaaactt ggttgggaga ttatctcaac aggtggaact aaggttgccc ttgataatgc
    17941 tggggtggat accattgcta tcgatgatgt gactggtttc ccagaaatga tggacggtcg
    18001 tgtgaagacc ctccacccaa atatccacgg agggcttctc gctcgtcgtg acttggatag
    18061 ccacttggaa gcggctaagg acaacaagat tgagctcatt gaccttgtgg tggtcaacct
    18121 ttacccattt aaggaaacta tccttaaacc agatgtgact tatgctgatg cagttgaaaa
    18181 tatcgatatt ggtgggccgt ctatgcttcg ttcagcagcg aaaaatcatg ccagtgttac
    18241 agttgtggta gatcctgctg actacgctgt ggttttggac gaattggcag caaacggcga
    18301 aacctcttat gaaactcgcc aacgtttagc agccaaagta tttcgtcaca cagcggctta
    18361 tgacgccttg attgcagaat acttcacagc tcaagtgggt gaaagcaagc ctgaaaaact
    18421 cactttgact tatgacctca agcaaccaat gcgttacggt gagaatcctc aacaagacgc
    18481 ggacttttac cagaaagctt tgcctacaga ttactctatt gcttcagcca aacagctcaa
    18541 cgggaaagaa ttgtcattta ataatatccg tgatgcagat gctgctatcc gtatcatccg
    18601 tgacttcaaa gatagtccaa ccgttgtggc tctcaaacac atgaatccat gtggaattgg
    18661 tcaagctgat gacatcgaga ctgcttggga ctacgcttat gagtctgacc cagtatctat
    18721 ctttggtggg attgtcgtcc tcaaccgtga ggtggatgct gcgacagctg agaagatgca
    18781 cggcgttttc ctcgaaatca tcattgcacc aagctatacg gatgaagcgc tagctatttt
    18841 gatcaataaa aagaaaaact tgcgtatcct tgccttgcca tttaatgctc aagaggctag
    18901 cgaagtggaa gcagaataca caggtgtagt cggtggactt ctcgtgcaaa atcaagacgt
    18961 ggtcaaggaa agcccagctg actggcaagt ggtgaccaaa cgtcagccaa ctgagacaga
    19021 agcgactgct cttgagttcg cttggaaggc tatcaagtac gtcaaatcaa atggtattat
    19081 cgtgaccaac gaccacatga cacttggtgt tggtccaggt caaaccaacc gtgtggcttc
    19141 tgttcgcctt gccattgacc aagccaaaga tcgtctgaac ggggcggtcc ttgcttcaga
    19201 tgccttcttc ccatttgcgg ataacgtgga agaaatcgcc aaagcaggaa ttaaggccat
    19261 catccagccc ggtggctctg tccgtgacca agaattcatc gaagcagcgg ataaatacgg
    19321 cttgactatg gtctttacag gtgtgagaca ttttagacat taagaagata aaagggaaga
    19381 aaacagtttc tttccttttt tggcttaaaa tgctaactga aacaagatta aaacgaactt
    19441 ttttgatata atgttggtaa ataattcgca aaagaggttg aggaatgaaa ctgcttgttg
    19501 tcggttctgg tggtcgtgag catgcgattg ctaaaaagtt acttgaatca aaagacgtgg
    19561 aaaaagtctt tgtagctcct gggaatgacg gtatgactct ggatggtctg gaattggtaa
    19621 atatatctat ttccgaacat tataaattga ttgacttcgc aaaggccaac gatattgctt
    19681 ggacctttat cggtccagat gacgcccttg cggctggtat cgtggatgat ttccatgcag
    19741 ctggtctcaa agcctttggt ccgacaagat tggcagcgga gctggagtgg tccaaggatt
    19801 tcgccaagga aatcatggtc aaatatggtg tttcgacagc agcctatggc acattttcag
    19861 atttcgagga agcaaaggcc tatatcgaaa agcatggtgc gcctatcgta gtcaaggcgg
    19921 atggcttggc gcttgggaag ggtgtcgtcg ttgctgagac ggttgagcaa gcggtcgaag
    19981 ccgctcatga gatgcttttg gacaataaat ttggtgactc aggtgcgcgc gtggttattg
    20041 aggaattcct tgaaggagag gaattttcac tctttgcctt tgtcaatggt gataagttct
    20101 acatcatgcc aacggctcag gaccacaaac gtgcctacga tggcgacaaa gggcctaaca
    20161 cgggtggtat gggtgcctat gcgccagttc cacacttacc acagagtgta gttgatacag
    20221 cggttgacac cattgtcaag ccagttctag aagggatgat taaagaaggt cgcccttatc
    20281 tgggagttct ttacgcaggg cttatcctga cagctgatgg accgaaagtc attgagttca
    20341 acgctcggtt cggagatcca gaaactcaga ttatcttgcc tcgcttgacc tctgactttg
    20401 ctcaaaatat cacagatatc ctggatagca aggagccaaa tatcatgtgg acggacaagg
    20461 gtgtgactct gggtgtggtt gtcgcatcca agggctaccc gctagactat gaaaggggcg
    20521 ttgagttgcc agccaagaca gaaggcgatg tcatcaccta ctatgcaggg gctaagtttg
    20581 cggaaaatag cagagcactg ctctcaaacg gcggacgagt ttatatgctc gttaccacag
    20641 cagataccgt caaagaagcc caagccagca tctaccaaga actatcccaa caaaaaatag
    20701 aaggactctt ctaccgaaca gatatcggaa gcaaggcaat taagtaaaga tataagaata
    20761 acgcgccgta gtcgccaaac acgataatgg tcgtcgtggt gaaaagacca gaacagtgaa
    20821 tgttctggtc agggggaaac ttggagaccg taggctcaaa gtttaggaat gaaaccgaag
    20881 gtttgcttcc gcctccatca cctaagacca ttatcaaaaa gaaaaataaa aattcacaaa
    20941 atacgttaat gatcgtatgg tttgcgagcg ttagcgagct aatatagaac aatcaccgcc
    21001 gttgtgaaag aacgattgga tgataatcca atcgttcagg gaaattggaa gaccttgggt
    21061 ttccaattta ggcatgagac acctttggtg gctgctgccg tccctcacaa gctaaggtga
    21121 ttgttgaaaa agaggaaaaa ggagaagaaa tgaaaccagt aatttccatc atcatgggct
    21181 caaaatccga ctgggcaacc atgcaaaaaa cagcagaagt cctagaccgc ttcggtgtag
    21241 cctacgaaaa gaaagttgtt tccgcacacc gtacaccaga cctcatgttc aaacatgcag
    21301 aagaagcccg tagtcgtggc atcaagatca tcatcgcagg tgctggtggc gcagcgcatt
    21361 tgccaggcat ggtagctgcc aaaacaaccc ttccagtcat tggtgtgcca gtcaagtctc
    21421 gtgctcttag tggagtggat tcactctatt ctatcgttca gatgccgggt ggggtgcctg
    21481 ttgcgaccat ggctatcggt gaagctggag cgactaacgc agctctcttt gccctccgtc
    21541 tcctctctgt agaagataag tccattgcgg atgcacttgc caactttgct gaagaacaag
    21601 gaaaaatcgc agaggagtcg tcaaatgagc tcatctaaaa caatcggaat tatcggtggc
    21661 ggtcaactgg gtcagatgat ggccatttct gctatctaca tgggccacaa ggttatcgcg
    21721 ctggatcctg cggcggattg cccggcctct cgcgtggcgg aaatcattgt ggcaccttat
    21781 aacgatgtgg acgccctccg tcagttggca gaccgttgcg atgtcctcac ttatgagttt
    21841 gaaaatgtcg acgctgacgg tttggatgcc gttatcaagg atggacaact ccctcaagga
    21901 acagatctgc tccgcatttc gcaaaatcgt atttttgaaa aggacttttt gtcaaacaag
    21961 gctcaagtca ctgtggcacc ctacaaggtc gtgacttcta gcctagactt ggcagatatc
    22021 gacttgtcga aaaactatgt cctcaagact gcgactggtg gctacgatgg tcatggacaa
    22081 aaggttattc gttcagaagc agacttggaa gcagcctatg cgctagcaga ctcagcagac
    22141 tgcgtcttgg aagaatttgt caactttgac cttgagattt ctgtcatcgt gtcaggaaat
    22201 ggcaaggagg tgacgttttt cccagttcag gaaaatatcc accgcaacaa tatcctgtct
    22261 aagaccatcg taccagcccg catttctgaa agtctagtag acaaggctaa agctatggca
    22321 gtgcgaatcg cagaacaact caacttgtct ggaactctct gtgtggaaat gtttgcgact
    22381 gatgatgacg ttattgtcaa tgaaatcgcc ccacgaccac ataactctgg gcactattct
    22441 attgaagcct gtgatttctc tcagtttgac acccatattc tcggtgttct cggagcacca
    22501 ttaccagtca tcaaactcca tgcgcctgcc gtcatgctta acgttctcgg ccagcatgtt
    22561 gaggccgctg aaaaatatgt cacagaaaat tcaagcgccc acctccacat gtatggtaaa
    22621 atagaagcga agcacaaccg caagatggga catgtgactt tgattagtaa tgaaccagat
    22681 agtgtgggag agttttaggg gagaggggtc taaagaaaaa atgtttgaaa aaattaaagg
    22741 aattaatata aaatcaggta tttttgaaga tgaaacaaaa ttagaactct ttgaaggaaa
    22801 ttttgaggga acaaatccag tacaaaacga tagggcaagt ttattgtttg gaaggaatgg
    22861 ttcagggaaa agtaccattg ctcgaggaat aaatcaatta aaaaatggtg agattggaac
    22921 agatagagta tcatttattg ataaaaataa taataatatt gtacttagtg atactgaacg
    22981 aaaatcgata tttgttttca atgaacacta tgttgatcag aaagtcaaaa ttgctcaaga
    23041 agggttagat acaattgtaa ttttaggtga acaggttgat atcgatgagg aactggatag
    23101 attaagaacg cagttatcag aatcacaaat tgaatctcaa gattattatg ctgaatatga
    23161 agaatattta gatgaaaaaa atgaaaaatc tccagatttt tggaaaaagg aaatgacaga
    23221 ttctttgaaa ggagtaggca actgggccga aagagatagg gagataaaag gaaatcgagc
    23281 tgcatctccc gttcataata atacctttca aaattttgtt gatttacaac caatcttaga
    23341 taaaaatgag ttagaggttg aattcaacaa taaaaaagct agatattttt caataagaga
    23401 ttccgcagtt actataaata atgaactatc tttacctgat attaattttg atagcaatga
    23461 attatcaact ttattgtctg aaaaaatcga agaacctgag ttgaattcta gggataagta
    23521 tttactgaca ttattatctg attccacaaa aggtgaacgt catttgagag aagttaaaga
    23581 tttctttgaa gatgaacatc aaaaaaaatg tcctttctgt actcaatcag tatcagaaga
    23641 tgttaaagtt gaactcacga atggcataac taaactacta tcaagagcag tcgaagaaca
    23701 ccaatccgca ttgagaggta aaaaaattga tgagattaat caagattttt ctggttatga
    23761 acagatagat ccaatattaa ttcagtctta tcaaaatagt attaatgctt tgaatgctaa
    23821 atttaacgaa attaactcaa taatcgataa gaagattgat aatccatata atatagttga
    23881 gttacctaat ataagctttt ctcaagaatt aagtcaagca gagcatgata ttgaaaaaat
    23941 taaccaagca attatcaaac ataattcaga aatctcgggt attcaaaagt taaaagtaga
    24001 tctccttcaa ataaataatg aattagcttt ttatgaaatt caagatgcat acaaaaagtt
    24061 tcaagagaaa acaaataaaa aagcaatttg tgaaaataat tataataaca gtagtaaacg
    24121 agtaaaggat tatgagaagc agatttctga tttagaagac aagaaactta atatagatat
    24181 tgcagttgat gaaattaata aaagtttaaa ttacatattt ttttcaaaaa atcggttagc
    24241 tatacagaat caaaacggaa aatactatct gttatcaaga ggtaagtctg tggtccccag
    24301 tagggtttcc gtaggggaac gaaatgcgct ggcattatgt tatttcttta ctgagataat
    24361 tcaacagaga gagttagcag atgcttatag tcatgaatat tttattgtta ttgacgatcc
    24421 aatttctagt tttgatatgg aaaataaagt tggaataacc tcgtatttaa aatattgttt
    24481 aactagattt tttaagggga atagtaatac tagagtttta ctaatgaccc atgataaaca
    24541 aacaatatat gactttgata tctttttgaa agagataatg gaatcctgta aagaagagga
    24601 aggtggacaa aaatctaaat acaagaagtt agaattggtt tctggtaaat tacaagaatt
    24661 caaaactagt actcacgatt atacagaact acttgaaata gtcttcggtt atgcattggg
    24721 aaatagtaca cctacttcgg aaagttttgt tgggaatgca atgagaaaaa ttttagaagc
    24781 ctatggtagt tttaattata agaagggaat tgccgagcta acaacagatc ctttaattgt
    24841 tgaaaaaatt gataaagaat acagaactta ttttgagaat cttatgtata gactggtttt
    24901 aaacggtgaa agtcatttta aggatccggt taaaactttg agtattgatt tctttgatac
    24961 catttctgat gaagaacgaa aaaaaacagc tagagattta ctagttttgc tttatctttt
    25021 agatgattta catgttttaa aacatttaga gggtgtatca aatgcggaaa atagacttga
    25081 acaatggaag tgtgagattt tagaataaga gaatcatacc atttgactta ttgcaatggt
    25141 tgaagtttgc atgatagctg attagagtaa tcaaaggatt attacttcct aattttattt
    25201 tctacaaacc ctaatttagc atctaataat gcaaagtttc ctgagcctca tagataaaaa
    25261 agatttttaa ggagaaaaac atgatcaacc gttactctcg ccctgagatg gcgaatattt
    25321 ggagtgaaga aaataaatac cgtgcttggc ttgaggtgga aatcctctct gacgaggcat
    25381 gggctgagtt gggggaaatc cctaaggaag atgtggcttt gattcgcaag aaggcggact
    25441 ttgacatcga ccgtattttg gaaattgagc aggagacgcg ccacgatgtg gtggctttca
    25501 cgcgtgcggt ttctgagact cttggtgaag agcgcaagtg ggttcactat gggttaactt
    25561 ctaccgacgt ggtggatact gcctatggtt acctctacaa gcaggccaac gacatcatcc
    25621 gtcgtgacct tgaaaacttc actaatatca tcgctgacaa ggccaaggag cacaagttca
    25681 ccatcatgat ggggcgtact catggtgtgc acgctgagcc gacaactttt ggtcttaaat
    25741 tggcaacttg gtatagcgaa atgaaacgca atatcgagcg cttcgagcat gcggctgctg
    25801 gtgtagaagc tggtaagatt tctggtgcgg ttgggaactt tgccaatatc ccaccatttg
    25861 tagaggagta tgtctgcgat aaacttggca tccgtgccca agaaatctct acacaagtcc
    25921 ttcctcgtga ccttcacgct gagtactttg cggttcttgc cagcattgcg acttcaatcg
    25981 aacgtatggc gactgagatt cgtggtctac aaaaatctga gcaacgcgaa gtagaagagt
    26041 tctttgctaa agggcaaaaa gggtcttcag caatgcctca caaacgcaac ccaatcggtt
    26101 ctgaaaatat gactggtctg gcgcgtgtca ttcgtggtca catgattacg gcttatgaaa
    26161 acgtcgctct ctggcacgaa cgcgatattt ctcactcatc agctgagcgt atcatcacac
    26221 cagatacgac cattttgatt gactacatgc tcaaccgttt tggaaatatc gtcaagaact
    26281 tgacagtctt cccagaaaat atgatccgaa acatgaactc gacttttggt cttatcttta
    26341 gccaacgggc tatgttgaca ttgattgaaa aaggcatgac ccgtgagcaa gcctatgact
    26401 tggtgcaacc aaaaacagcc tactcttggg acaaccaagt agactttaaa ccacttcttg
    26461 aggcagattc agaagtaaca tcacgtctca cacaagaaga aatcaatgaa atcttcaacc
    26521 caatttatta caccaaacga gtggatgata tctttgaacg tcttggacta ggtgattaat
    26581 taaaaaataa acagcgagct tcaatctcgc tgtttatttt ttatcgaaaa gacttagtct
    26641 tcttttcttt tagtgagtcc ataggctgct agtgtggaca tgagtcctgc gactactagt
    26701 cctgcagaat cgtgagttcc tgtttcagga agttttttct ctgttaccac aggagctgga
    26761 tcttgaggaa gagctttgct ttcctcagca ggagcagttg atggagctgg ttggcttggg
    26821 atttctagtc ttggtttttc ttcagcaata gcggcttgtc cgttttcatc gcctacatgt
    26881 gttaccatag ttccgacttc gactatttga gtaacggctt cctgtgctac gacactattt
    26941 acaagtgttt tcacttcctt accatcggca gaagtgctca cagagtagaa gttgctacga
    27001 tgtccattga cgcccttagt aatgacttgt gtttttcctt tgagtaagag tggattttca
    27061 cgagtcactg tggtaaatgg aatttcttct ttttggatat ccagtctagg ttttacctca
    27121 gtagttggtg caagaccact ttcatcaccc ttgtgagtta caggagcgcc aacttcaacc
    27181 acttggttta taacttcttt ggttacctgg ctatcaagga ctgtttctgt tgtttttcca
    27241 ttttcagtga gtacagagat gtaatgagtt cgttcacctt tgactcctgc tgtgataata
    27301 ttttcctgac cagctgggag gttaggattt tctttcttga taacttcaaa tggaatttct
    27361 tcagttcttg tgatgagttc tggtctggtt tcaacattgg cagccacttc attttcatcc
    27421 aggcttcctg aatgagttgc agctggtttg aggccttgaa gagcggcttt taggttggct
    27481 acaagtgtgt caagctcagc ttgtttatta cggttgaggt tgtaatttag agctgtttta
    27541 gctgcgtcaa gggcctcaag actttcttta ctatatcctt ctaagtttgt aggaatttta
    27601 gctaattctt cgcggagagc attataatta gcacggaagt agtctttgtt gtggtctgca
    27661 aaggcagtca tgagttcaaa gatttcctct tccttgtact cagcgcttgg tctatctgcc
    27721 cagattgaaa gcatacttcc gactgttgga agatctactt caggatattt ggtagaagct
    27781 agttgattga atggaacttt accagaattt tcaactgctt ttgaaagagg gtaagcttca
    27841 tcttgtttgt gattgcctat aacataatac cagtcaccgt tggtattcaa gaatttatag
    27901 cctttgcttg ctaggtattg aggtgatgcg aggttatatc cccaccagcc tttagaccag
    27961 taagaaatca agacatcttt gtcaaactga acatcgtcct tgtcttcata gtagaagcca
    28021 tcgttgaagg ccattggttg aagccctctt tctttggcca tagctgcgag ggtgttggca
    28081 tattcggcaa atttgccata gagttgatac cacttgaggt agtaccagcc ttgggcacta
    28141 gtcgcatcgt tggcgtattc gtcagtacca aagttgaaaa tctttgtttt acctgcaaag
    28201 aagtccatgt atttaccgat gagggctttt acaaagttca tcgcttcttc gtttttcaag
    28261 tccatagttg tttttgaaac tttatcaaag tgggcttgag gatttttaat acctaatttt
    28321 tccatggcaa ccagcatagc atccatgtga cctggactgt taatagctgg gatgagacca
    28381 atgtccttag atttagcgta ttcaattagc tctgtcactt ctgcctgtgt tagtgcagta
    28441 ccgtttggat cgtcgtagta agctttagtt ccttcgataa tagctttttt aacgtcatca
    28501 ctagcatagg tttttccgtt ggcagtaatg gtcatatcat tgagtagaaa gcgaagtccg
    28561 tcatttccta gaaggagatg gacatcagaa tatccgagct cactggcctt gtctacgatg
    28621 cgtttgagct ggtccagagt aaagtatttg cgtccagcat cgattgagat taccttgttt
    28681 ttggcaagtt tttcaacctc acgtttagct tcttcttctt tttgagcttc aggcgtgagg
    28741 gtcaagttgt tgacagtttc ttgaagttta gcaatggctt gatcaatcgt atcttgttgg
    28801 gcacggctaa ggttgctatc gagagagcga atagcttttt cagcttcttt tacggccgcg
    28861 acgctttctg cagtataacg gttcaggtct tttggtacct cgttaagtgc ttgctctgca
    28921 gattcataat cagctgcgaa gtattcagcg ttggcatttg caaaatgacg catgagtttg
    28981 aagaggtgtg atggtgaata acgtgcagat ggagtgtcag cccaagcagc taccatacca
    29041 ccgatgattg ggatatcagc tccttctgtt tttggtacag aagtgattgg tgtgttttta
    29101 ataccattga gcccctgatc gagattgtac cagccttggc catcagcgtt tcgtccaaga
    29161 acgtagtacc aagcatcatt ggtattaagg atttggtgac ctttttcagc tagtagttta
    29221 gaagaagcga catcgtagcc tccccaacca ccagtccaca tagaaacgat gatgtctttg
    29281 tcaaaactac caaagcttgt gtcgctattg tagtagatac cgtcgttaaa ggccattggt
    29341 ttgagaccgt gcgattttac aatacgagcg aggtcattgg cgtaggcaat aaatttttca
    29401 tagcctttta cagggtagcc ttcgtttgga tagtatttat cagcttgaag cacactccaa
    29461 cctttagcat ctgtcgcatc attggcatat tcatcaagtc cgatgttgaa gatttcagtc
    29521 tttttcgcga aataagcagc atacttgtcg ataagggctt ttgtaaaagc gacagcttgt
    29581 tcgttgtcaa gatcgacagt acgggctgat ttcttcccaa aatagctaaa gttagggttt
    29641 tggattccca attctttcat ggcattgaga atcgcatcca tgtgtccagg actatttact
    29701 gtcggaatga gaccgatacc tttatctttg gcatagttaa tcagatctgt catttgactt
    29761 tctgttaagt gattgccgtt tggatcgttg taataatcat ttgtaccttt ttcaatggcg
    29821 cgtttgacat cgtcactggc ataggtcttg ccgttagctg tgatgctcat atcgtccaac
    29881 atgaaacgga gtccatcatt tccgactaat aggtgtaaat cagtgtagcc ataatgtttc
    29941 gctttatcga tgatttcctt gagctgttct ggtgagaaat atttacgtcc agcatcaata
    30001 gaaacaattt tctttttcgc tagtttttca tttacagttg cagcacgttc ctttcctgtc
    30061 tctgtttccg gtttgtcagc ctctgctttc gcttcatctt ttttagctgg tttatccttg
    30121 tcagtcttgt ctgtatttga ctctttagaa tcaacctctt tcgcttcttc ctttttaggg
    30181 ctagcttctt cttccttttt attagcagtt tctttttcag cagaagttgg agttaccacc
    30241 tctgctttat cactaggagt tgaactaact tcctcttgtg gtttttcttc tgtttttgga
    30301 agactagcta ccttatcagt agctggagtt tctgtttcta cagtttttgg agcttctggt
    30361 tgaagctctg ctttaggtgt ttcctcagtc cgattttcgg atgattgagg ggaatcagaa
    30421 accgtatgga tggtcggttg gttttctgta gtagtaggag taactccatc ggctgcaaca
    30481 gtctgtgctt ggaaggcaaa tccaattaga acagaagctg ctcctacagc gtatttacga
    30541 atagaaaaac gctgttgttt ttcatgtttc attgcaaaac ctcctgattg cattgttata
    30601 ttgatagcga ttatataaat caacgccttt attttatttc ttatattaac gagagtcaag
    30661 aggagatgac aaaaaactat aataagtata aaaaaatata aaatttaaac ttaagatttc
    30721 agattggtcg aaaaaataca tatatatatc tagtataatt tttggttcta tttctataaa
    30781 atattccaca aattatagaa tcttccaaaa ataggtaagc gctacctttt tggtgtggta
    30841 taataagcat agaaaaagcc cgagcgatta ggctcaggct ttcttcttag tgatcacggt
    30901 cacatgagat gaatttaatc ttgtagtaat cagatcgttt gtaagtttca ctgtattcta
    30961 aaacttggcc agttgattcg agtttggtga ttttagtttg taggacagta gggaattgtt
    31021 catcgactcc gaggactgaa gccgcatgtt ctggagttgg aaagactatt tcgttgattt
    31081 cttcaaagtg ttcatcattc atgtgaatgt ggtagtctaa cttgaaacga ttatagatag
    31141 aactatagta ttcaaggttt ggataatttg cgttgatata ttgttctggg atgtaggatg
    31201 tatggtagat ataaacgaca ccgtttgatt cgcggatacg ttcaatcttg tagtagaatt
    31261 gatcgccgcg tagacccaat ttttccaagt aaacaagctt gtttccgcgt tcaattgaaa
    31321 gaacagttac cttatcatct ttagcattga agagttcaat atctgaaaac tctacaagct
    31381 tgtgtttgcg tgcacgtgaa acgaaggttc cttttccttg ttggcggaca atatagccat
    31441 ctttggcaag gtcgtttaag gcgcgaacaa ctgtgataga gctgacatcg tacattgaaa
    31501 tgagttctgc ttcagtgtaa aatttatctc cactgctaaa ctgcccagag atgattttat
    31561 tttttaattc gtcttttatg tattgatatt tgggaattgc catattttta cctctatttt
    31621 ccttctccat agaaaatttt accataaaag cgaaaaaaat agtagtcttt tgaataaaaa
    31681 attagaataa tagtttgaaa aattaagcga tatagggatt gctcatattt tatcaatgca
    31741 ttctatacaa aattatttta ggtcctatat tccgaattta aagagcgttt gaaatgggtc
    31801 taaaaatgtt tgaaactaat tgaatgtgtg tataatagta aaaatgcagt aaatatcccg
    31861 acaatttcta ttgacaattc aaacagattg gtttataatt aatataacaa caaatgaaag
    31921 cgcaaacttt cgcggtcgga aggtagtttt atgacacgat ttgagatacg agatgatttc
    31981 tatctcgatg gaaaatcatt taagatttta tctggtgcca ttcattattt taggattcct
    32041 ccagaggatt ggtatcattc gctctataac ttgaaggctc ttggttttaa tacggtagag
    32101 acttatgttg cttggaattt acacgagcct cgtgaaggtg agtttcattt tgaaggtgat
    32161 ctggatttag agaaatttct ccaaatagcg caggatttgg gtctctacgc aattgtgcgt
    32221 ccgtctccat ttatctgtgc ggaatgggaa ttcggtggct taccagcttg gctcttgacc
    32281 aagaacatgc gaattcgctc atccgaccca gcatatatcg aggcagttgg tcgctactat
    32341 gatcagttat tgccaagact ggtgcctcgt ttgttgaaca atggtggcaa tattctcatg
    32401 atgcaggttg aaaatgagta tggttcttac ggagaagata aggcttacct gagagcgatt
    32461 cgacagctaa tggaagagtg tggcgtaacc tgtcccctct ttacatcaga tggtccatgg
    32521 cgagctactc tgaaagctgg aaccttaatt gaagaggacc tctttgtaac aggaaacttt
    32581 ggttctaagg caccttacaa cttttcgcag atgcaggaat tctttgatga acatggtaag
    32641 aaatggccac tcatgtgtat ggagttctgg gatggttggt tcaatcgctg gaaagaaccg
    32701 attatcacac gggatcctaa ggaattggca gatgcagttc gagaggtttt ggaacaaggc
    32761 tctatcaatc tttacatgtt ccacggtggt acaaactttg gtttcatgaa tggttgctca
    32821 gctcgaggaa ctttggacct gccacaagtt acatcttatg attacgatgc ccttctggat
    32881 gaagaaggaa atccaactgc taaatatctt gcagtcaaga agatgatggc aacacatttt
    32941 tcagagtatc cgcagttgga accactctac aaagagagta tggagttgga tgctattcca
    33001 ctagttgaaa aagtttcttt gtttgaaacc ttagatagct tgtcaagtcc tgtagaaagt
    33061 ctctatcctc aaaagatgga ggagctggga caaagttatg gctacctact ttatcgaaca
    33121 gaaacaaact gggatgcaga agaagaaaga cttcgtatca ttgatggtcg agatagggcc
    33181 cagctgtatg tcgatggtca gtgggttaaa actcaatatc agacagagat tggggaagat
    33241 attttttatc aaggtaaaaa gaaagggcta tctaggttag atatcttgat agaaaatatg
    33301 gggcgtgtca actatgggca taagttctta gcggatacgc aacgtaaggg aattcggaca
    33361 ggggtctgta aggatctgca tttcttacta aactggaaac actatccact cccactagac
    33421 aatcctgaga aaattgattt ttcaaaagga tggactcaag gacaaccagc cttttacgct
    33481 tatgacttta cagtcgaaga gccaaaagat acttacctag acttgtctga gtttggtaag
    33541 ggagttgcct ttgtcaatgg gcagaatcta ggacgttttt ggaacgttgg cccaactctc
    33601 tcactttata tccctcatag ctatctcaag gaaggtgcca accgtatcat tatctttgaa
    33661 acagaaggtc aatataaaga agagattcat ttaactcgta aacctacact aaaacatata
    33721 aagggggaaa acttatgaca attgtaggat gccgtattga tggacgtttg atccacggac
    33781 aagtagccaa tctttgggct ggaaaactaa atgtttcacg cattatggtt gtagacgacg
    33841 aagttgtcaa caacgatatt gaaaagagtg gtttgaaact tgcgacacca ccaggtgtga
    33901 aattgagtat tttgccagtt gagaaagctg cagccaatat tcttgctggt aaatacgata
    33961 gccaacgtct ctttatcgtg gctcgtaaac cagaccgctt ccttggtttg gtagaagcag
    34021 gtgtaccact tgaaaccctt aatgttggga atatgtctca aacaccagaa actcgttcta
    34081 ttacacgttc tatcaacgta gtagacaagg atgtggaaga cttccacaaa ctggcagaaa
    34141 aaggtgttaa acttactgct cagatggttc caaatgatcc aatttcagac tttttgagct
    34201 tattaaaata ggaaaaaaat ttttaggagg tcattgttat gatacaatgg tggcaaattt
    34261 tacttctcac tttgtactca gcttatcaaa tctgtgatga gttgacgatc gtttcatctg
    34321 caggttcccc tgtatttgct ggtttcatta ctggtttaat catgggagat gtgactactg
    34381 gtttacttat cggtggtaac ttgcaactgt tcgttcttgg ggttggtacc ttcggtggtg
    34441 cttctcgtat cgacgcaact tctggtgcgg ttcttgcgac agccttctct gtttcacaag
    34501 gaattgatgc accgcttgcc attactacaa tcgctgtacc agtagcagct ctcttgactt
    34561 acttcgacgt tcttggtcgt atgactacta ccttcttcgc tcaccgtgtg gatgctgcaa
    34621 tcgaacgctt tgactataaa ggtattgaac gcaactactt gcttggtgcg attccgtggg
    34681 ctctatctcg tgcccttcca gtcttctttg cccttgcttt tggtggtgcc tttgtacaat
    34741 cagtagtaga cttcgttgaa gcctacaaat gggttgcaga tggcttgaca cttgcaggac
    34801 gtatgcttcc aggtcttgga tttgcaatct tgcttcgtta ccttccagtt aaacgtaacc
    34861 ttcactacct tgctatggga tttggtttga cagctatgtt gactgttctt tactcatatg
    34921 taacaggtct tggtggcgct gttgctggta tcgtaggtac tcttcctgct gaagttgctg
    34981 aaaaaattgg tttcgtgaac aacttcaaag gtttgtctat gattggtatt tctatcgtag
    35041 gtattttcct tgcagtgctt cacttcaaaa atagccaaaa agtagctgta gcagcacctt
    35101 ctacaccatc agaaagtggg gaaatcgaag atgacgaatt ctaattacaa acttacaaaa
    35161 gaagatttta atcaaatcaa caaacgtagc ttgtttactt tccaattagg ttggaactac
    35221 gaacgtatgc aagcttctgg ttacctttac atgatcttgc ctcagttgcg taaaatgtat
    35281 ggtgatggaa ctcctgaatt gaaagaaatg atgaaagttc atactcaatt cttcaatact
    35341 tcaccattct tccataccat tatcgctggt tttgaccttg ccatggaaga aaaagatggt
    35401 gtaggttcaa aagacgccgt taacggtatc aagacaggtt tgatgggacc attcgctcct
    35461 cttggggata caatctttgg ttcacttgta cctgctatca tggggtcagt cgcagcaact
    35521 atggctatcg ctggccaacc ttgggggatc ttcctttgga ttgcagttgc agtagcgtat
    35581 gacatcttcc gttggaaaca gttggaattt gcttacaaag aaggggttaa ccttatcaac
    35641 aacatgcaaa gtaccttgac agctttgatt gacgctgcat ctgtacttgg tgtcttcatg
    35701 atgggtgctc ttgtagcaac agtgattaac tttgaaattt cttacaagtt gccaatcggt
    35761 gaaaagatga ttgatttcca agacatcttg aaccaaatct tcccacgttt gcttccagca
    35821 atctttactg cctttatctt ctggttgctt ggtaagaaag gtatgaactc tactaaagct
    35881 atcggtatta ttatcgtact tgctttggct ctttctgccc ttggtcactt tgcacttgga
    35941 atgtaattcc ttatgactaa atcattaatt ttggtgagcc atggtcgctt ctgtgaggag
    36001 cttagaggta gcacagaaat gattatgggc ccacaagaca acatttacac agtagctctt
    36061 cttccagaag atggcccaga agaatttact gctaaatttg aagctgttat tgaaggattg
    36121 gatgatttcc tagtctttgc ggatcttctc ggtgggacac cttgtaatgt ggtgagtcgc
    36181 ttgatcatgg aaggtcgtga tattgacctt tacgcaggga tgaatcttcc aatggtgatt
    36241 gaatttatca atgcgagcct tacaggcgca gatgcggact acaagagccg tgctgcagaa
    36301 agcattgtga aagttaatga cctgttagcg ggcttcgatg atgacgaaga tgaataatac
    36361 tcttcgaaaa tctcttcaaa ctacgtcaac gtcgccttgc cgtaggtata tgttactgac
    36421 ttcgtcagtc ttatccggca acctcaaagc agtgctttga gcagcctgcg gctagtttcc
    36481 tacagatttt agttggaact cgattcaatt catgtgacaa cgtgaaaatc gttagagcat
    36541 tttatataga atatacatgg gaatgtagct tactcccatt cccatattta atagaaaaag
    36601 aggaactcaa tgctacatta tacaaaagaa gacttgctcg aattgggtgc agaaatcact
    36661 acgcgtgaaa tctaccaaca gcctgatgta tggagagaag cttttgaatt ttatcaagca
    36721 aaacgtgaag aaattgcagc cttcctacaa gaaatcgctg ataaacatga ctatattaag
    36781 gttatcttga caggtgctgg gacttctgct tatgtgggag ataccttgct accttatttt
    36841 aaggaagtct atgacgaacg caaatggaat ttcaatgcta ttgcgacaac agatatcgtt
    36901 gccaatccag caacctattt gaaaaaagat gtggcaactg tccttgtgtc ttttgctcgt
    36961 agtgggaatt cgcctgaaag tttggcgact gttgatttgg ccaaatcctt ggtggatgag
    37021 ctttatcaag tgacgattac ttgtgcagca gatggtaaat tggctcttca agctcacggt
    37081 gatgatcgta atctcttgct cttgcaacca gctgtctcta atgatgctgg atttgccatg
    37141 acttctagct ttacgtctat gatgttgaca actctcttgg tctttgatcc tacagaattt
    37201 gctgttaagt ctgaacgttt tgaagttgta tctagtcttg cccgtaaagt tttagacaag
    37261 gcagaagatg tcaaagagct cgttgattta gactttaacc gtgtcatcta tctaggcgct
    37321 ggtcctttct ttggacttgc tcatgaagct cagctcaaga ttttggaatt aactgctggt
    37381 caagttgcga ccatgtatga aagcccagtt ggcttccgtc acggtccaaa atctcttatc
    37441 aacgacaata cagttgtttt ggtctttggt acaacgacag actacactcg taagtacgac
    37501 ttggacttgg ttcgtgaagt tgctggtgac cagattgctc gtcgtgttgt gcttttgagt
    37561 gatcaagctt ttggtcttga aaatgtcaaa gaagtggccc ttggttgtgg cggtgtcttg
    37621 aatgatattt accgtgtctt cccttacatc gtttatgccc aactctttgc tttattgact
    37681 tcactcaagg tagaaaataa accagataca ccgtctccta caggtacagt aaaccgtgta
    37741 gtacaaggtg tcataattca cgaatatcaa aagtaagaca gtgtttatga attcttgaca
    37801 agaggatttg taaattatca gataaaccat agattgtcag tacgctttct atggtttgtt
    37861 tgcttgagag aaatagtaaa aggagaacag aatgaaagca tacacagagc gtgtatttgg
    37921 aaatgttgag ggtgaggatg tcttggccta tcgatttgag acagacggtg gctaccaact
    37981 tgaggttatg acttatggtg cgactatctt gcgctatgtc gcacctgaca aggctggaaa
    38041 ttttgccaat gttatcttgg gatttgatga ctttgatagt tatgtaggca atagtcccaa
    38101 gcatggagca agtgtaggtc ctgtagcggg tcgtattgca ggtgcgacct ttgagctcaa
    38161 tggtaagacc tatgaccttg aggttaataa tgctagcaac tgtaatcaca gtggttcaac
    38221 tggttgggat tccagcttgt ttgaagttga agaagtaagc gatcatggct tgactctcta
    38281 cacagagcgt acagatggga caggagggtt ccctggaaat ctcaagattt ggatcagtta
    38341 tcacttggaa gaaactggtg cctatgaaat cagctacaag gtaacgaccg atcaggatac
    38401 gctggtcaat ccaaccaacc acagctattt caacttgtct ggtgatttca cgcagacgat
    38461 tgaccgtcat gtcttccaac taaacacaga gggcatttac tcaatcgctc ctgacggtgt
    38521 tcctgccaaa actccagaag ccaaccgtga tgtggtcaaa cacgtctaca atggtacctt
    38581 gttgaaggat atctttgcag aagaagatga gcaaatccag ctggcatcag gtttggatca
    38641 tccatttgcc cttcctgcag gccatgacaa tgctggattc ctttatgacc aaaattcagg
    38701 tcgcttcctg cttttcaaga cagaagctcc ttgctttgtg gtctacacag caaactttgt
    38761 ggatgaaagt gtcatcatag gaggtcagcc aatgctacag cacaatggga ttgctcttga
    38821 agcgcaagct ttaccagatg ccattcacag tgaccttaaa ggccaagtca ttcttaaagc
    38881 tggtcaaacc ttcaccagta agacacgtta tgaacttgtt gtgaaataaa aaaagctggt
    38941 caaaaagtct ttaaaattaa aataacgcat attgtcaggt gatgaaaagt ttgataatat
    39001 gcgttttatt atgaaatgat ttactttata ttatcctgaa atggtgttat ttttgagtta
    39061 tctggcttga ctttcttgat ggaaattata taatagttgt aacaataata attacaacta
    39121 gaaaagagga ccatttatga cctatgaata caagagtcac atttatttgg cagagacagc
    39181 tttaaatgta aaggatttgg ccagtcaaac agccttttat cagcaagtta ttggtttaga
    39241 aatcttatct caaactgaga cagagtccat tctaggcctt ggtggaaaag tcttggtaca
    39301 gctgattcaa gcacaagaga gcggagaagt gagggaatat tatggtcttt accatttggc
    39361 cattctcttg cccacacgca aggctttagc tgatgtcttg aaacacctga cagatttaca
    39421 aattcctctt gtcggcggtg cagaccatgg ttacagtgaa gctatttact tggaagattt
    39481 ggagggaaat ggcattgaac tctatcgaga taagccagtt tccacatggg atattcgaga
    39541 agatggacgc attatcggag tgacggaggc tcttgcggcg caggacattt atgagttggg
    39601 ggaaagagta gagcccttta tcctggcaga aggtacaaga atggggcata ttcatctttc
    39661 cgtcaaggat agtcgaaagt ccagccagtt ttatcaaaag gtgttagggc tagagaataa
    39721 attcagtgtg cctggcgcta gttggattgc ggctggagat taccatcatc atttagcagt
    39781 taacgaatgg ggaggaaaag gtctggcttc gcgtaagcaa ggcttaccag gtttagccta
    39841 ctatgtcatc gaagtcgcac ataaaaaaga actgttaacg attgcccaac gagcacaaga
    39901 agttgacgca ccaatcaaat ggatgacatc gatccaattg gaaatcacag actcagatgg
    39961 catcgtgacc cgtattcgtt tagcaaggta aaattaggaa tttttaataa gttataagta
    40021 ttgctagttt gctttttgaa cggtctttgg taacagaact gcgtgagaat tttgacaaag
    40081 aagctgatta gagatataat gaagaaaaat cgagcaagga aaaagaactg acaaattcaa
    40141 agtatattac ttgtttgaaa cgttcagagg gccagttgtg tgggattcaa aagatgattg
    40201 aaggagatcg tgactgtgct gatattgtga cgcaactgac agcagtgaaa tctagtgtag
    40261 agcgcgtgat tgagatgata attaccgaaa atcttactga atgtatcaat cagcccctag
    40321 atgattctga agctcaaaag gaacgcctag aaaaggctat ccgatacttg attaaacgga
    40381 aataaatgaa tgttttgaga cgatatgtgc aaaggtctat taactattag aatagtttaa
    40441 tgtgagtcaa aagaagttgt aaaaaatctc taaaattaaa aaaacgcata gtatcaggtg
    40501 ttgaatgtac tgacccccaa aagttagatt ttttctgtct aacttttggg gtgcagttca
    40561 taagaacctt ggtaatatgc gttttattat gtagagactt atactcttcg aaaatctctt
    40621 caaaccacgt cagcttcacc ttgccgtaga
//
LOCUS       DBEJHE010000019        38968 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC4 isolate 671759
            SAMN38261586-rid24793303.denovo.19, whole genome shotgun sequence.
ACCESSION   DBEJHE010000019 DBEJHE010000000
VERSION     DBEJHE010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261586
            Sequence Read Archive: SRR26833752
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 38968)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38968)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576136.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576136.1
            Genome Coverage       :: 109x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 19:48:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,067
            CDSs (total)                      :: 2,029
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 131
            CDSs (without protein)            :: 131
            Pseudo Genes (ambiguous residues) :: 0 of 131
            Pseudo Genes (frameshifted)       :: 64 of 131
            Pseudo Genes (incomplete)         :: 59 of 131
            Pseudo Genes (internal stop)      :: 46 of 131
            Pseudo Genes (multiple problems)  :: 32 of 131
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38968
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261586-rid24793303.denovo.19"
                     /strain="GPSC4"
                     /isolate="671759"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            498..878
                     /gene="dhaM"
                     /locus_tag="ACL3EZ_001304"
     CDS             498..878
                     /gene="dhaM"
                     /locus_tag="ACL3EZ_001304"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047324 - phosphoenolpyruvate-glycerone
                     phosphotransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase phosphoryl donor subunit
                     DhaM"
                     /protein_id="HGR0392868.1"
                     /translation="MESIGIGLVIVSHSKHIAEGVVELISKVAKDVPITYVGGTEGGG
                     IGTSFDQVDRVVSENPADTLLAFFDLGSAKMNLKMVTDFSDKSIIINRVPIVEGAYNA
                     AALLQAGAELSVIQTQLAELEINK"
     gene            1338..2051
                     /locus_tag="ACL3EZ_001305"
     CDS             1338..2051
                     /locus_tag="ACL3EZ_001305"
                     /EC_number="3.1.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000499426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008253 - 5'-nucleotidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HGR0392869.1"
                     /translation="MFYKFLLFDLDHTLLDFDAAEDVALTQLLKEEGVADIQAYKDYY
                     VPMNKALWKDLELKKISKQELVNTRFSRLFSHFGQEKDGSFLAQRYQFYLAQQGQTLS
                     GAHDLLDSLIERDYDLYAATNGITAIQTGRLAQSGLAPYFNQVFISEQLQTQKPDALF
                     YEKIGQQIAGFSKEKTLMIGDSLTADIQGGNNAGIDTIWYNPHHLENHTQAQPTYEVY
                     SYQDLLDCLDKNILEKITF"
     gene            2065..2712
                     /locus_tag="ACL3EZ_001306"
     CDS             2065..2712
                     /locus_tag="ACL3EZ_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0392870.1"
                     /translation="MTTKKANITIEEYIEMSEVDFNEAVNYEFTSDTCQLANSIYQSL
                     FKFFDKKNFSGDLIFTWKSPSLVKEGDYIGRRDSQVDNLRVIGNIFPNYLTNRKYSLN
                     MNRNGCMGDFPHDFFDIYLDHVAKYAYEQKVNNIKEYYPLKRAILHQENALYFRLFSN
                     FDDFLEKNYLKTIWQVSKETPFSEMDFNIFKNISEKIIFERGSKMLNDLKSNYKK"
     gene            2850..3503
                     /locus_tag="ACL3EZ_001307"
     CDS             2850..3503
                     /locus_tag="ACL3EZ_001307"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004844 - uracil DNA N-glycosylase
                     activity [Evidence IEA];
                     GO_process: GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HGR0392871.1"
                     /translation="MEHSSWHALIKAQLPEGYFGKINQFMEQVYSQGIIYPPKEKVFQ
                     ALLTTLLEEVKVVILGQDPYHGPGQAQGLSFSVPDSIPAPPSLQNILKELSDDIGVKK
                     SHDLTAWAEQGVLLLNACLTVPAGQANGHAGQIWEPFTDAVIQVVNHLDRPVVFVLWG
                     AYARKKKALVTNPHHLIIESAHPSPLSVYRGFWGSKPFSKANAFLKETGQEPIDWLR"
     gene            3513..3977
                     /locus_tag="ACL3EZ_001308"
     CDS             3513..3977
                     /locus_tag="ACL3EZ_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003012002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HGR0392872.1"
                     /translation="MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGE
                     TPQECAAREILEETGLKAKPVLKGVITFPEFTPDLDWYTYVFKVTEFEGDLIDCNEGT
                     LEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE"
     gene            3990..5258
                     /locus_tag="ACL3EZ_001309"
     CDS             3990..5258
                     /locus_tag="ACL3EZ_001309"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004151 - dihydroorotase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HGR0392873.1"
                     /translation="MLLIKNGRVMDPKSGLDQVCDVLVQDGKIIKIASEITEEGAETI
                     DATGLVVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGFTTVVMMANTSPTISDVE
                     TLQAVLQSAAKEKINVKTVATITKNFNGKNLTDFKALLEAGAVGFSDDGIPLESSKIV
                     KEAMEEAKKLNTFISLHEEDPGLNGVLGFNENIAREHFHICGATGVAEYAMMARDVMI
                     AYATKAHVHIQHLSKEESVKVVEFAQGLGAEVTAEVAPQHFSKTEALLLTQGSNAKMN
                     PPLRLESDRRAVIEGLKSGVITVIATDHAPHHVDEKNVEDITKAPSGMTGLETSLSLS
                     LTYLVEAGELSLMELLEKMTYNPAKLYNFEAGYLAENGPADITIFDAKADRFVDSHFA
                     SKAANSPFIGETLKGQVKYTICKGQIVYQA"
     gene            5272..5532
                     /locus_tag="ACL3EZ_001310"
     CDS             5272..5532
                     /locus_tag="ACL3EZ_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0392874.1"
                     /translation="MNYFRKRRERQAKSNSGIYCPAANRSKIQYETKEKADHAVQYDN
                     GGLVRSYYCRTCACWHTTSKSNKPPLSLKNYGLKLFGLDKSE"
     gene            5543..6904
                     /gene="pdrM"
                     /locus_tag="ACL3EZ_001311"
     CDS             5543..6904
                     /gene="pdrM"
                     /locus_tag="ACL3EZ_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-coupled multidrug efflux MATE transporter
                     PdrM"
                     /protein_id="HGR0392875.1"
                     /translation="MYKTKCLREKLVLFLKIFFPILIYQFANYSASFVDTAMTGQYNT
                     MDLAGVSMATSIWNPFFTFLTGIVSALVPIIGHHLGRGKKEEVASDFYQFIYLALGLS
                     VVLLGMVLFLAPIILNHIGLEAAVAAVAVRYLWFLSIGIIPLLLFSVIRSLLDSLGLT
                     KLSMYLMLLLLPLNSGFNYLLIYGAFGVPELGGAGAGLGTSLAYWVLLGISVLVLFKQ
                     EKLKALHLEKRIPLNMDNIKEGVRLGLPIGGTVFAEVAIFSVVGLIMAKFSSLIIASH
                     QSAMNFSSLMYAFPMSISSAMAIVVSYEVGAKRFDDAKTYIGLGRWTALIFAAFTLTF
                     LYIFRGNVASLYGNDPKFIDLTARFLTYSLFFQLADTFAAPLQGILRGYKDTVIPFYL
                     GLLGYWGVAIPVATLFDSLTDFGAYSYWIGLIISLIVSGALYRWRLTVIMKRFESLAK
                     SKR"
     gene            7058..8026
                     /locus_tag="ACL3EZ_001312"
     CDS             7058..8026
                     /locus_tag="ACL3EZ_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HGR0392876.1"
                     /translation="MSTLDKNLLLEMFRKMEEIRRMDLKIAQLVKKGKVPGMTHFSVG
                     EEAANVGAMLALNPDDLITSNHRGHGQAIAKGIDLNGMMAEILGKYTGTCKGKGGSMH
                     IADLDAGNLGANGIVGGGMGIAVGAALSQQMQNTGKIVVCFFGDGATNEGVFHEAVNM
                     ASIWNLPVIFYCINNGYGISADIKKMTNIEHIHQRSAAYGIPGMFIEDGNNVIDVYEG
                     FQKAVDHVRSSNGSVLIESVTYRWLGHSSSDPGKYRTREEVELWKQKDPIENLRNYLI
                     ENNIASAEELEEIQAQVKEAVEASVKFAEESPFPPLESAFEDIYAD"
     gene            8042..9034
                     /locus_tag="ACL3EZ_001313"
     CDS             8042..9034
                     /locus_tag="ACL3EZ_001313"
                     /EC_number="1.2.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HGR0392877.1"
                     /translation="METKTMSFRDTIILAMSEEMRRDENVFLMGEDVGVFGGDFGTSV
                     GMLEEFGPERVRDCPISEAAISGAAAGAAMTGLRPIVDMTFMDFSVIAMDNIVNQAAK
                     TRYMFGGKGQVPMTVRCAAGNGVGSAAQHSQSLESWFTHIPGLKVVAPGTPADMKGLL
                     KSSIRDNNPVIILEYKSEFNQKGEVPVDPDYTIPLGVGEIKRQGTDVTVVTYGKMLRR
                     VVQAAEELAEEEISVEIVDPRTLVPLDKDIIINSVKKTGKVILVNDAHKTSGYIGEIS
                     AIISESEAFDYLDAPIRRCSGEDVPMPYAQNLENAMIPTVESIKDAIRKTYNKD"
     gene            9252..10295
                     /locus_tag="ACL3EZ_001314"
     CDS             9252..10295
                     /locus_tag="ACL3EZ_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045254 - pyruvate dehydrogenase complex
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006086 - acetyl-CoA biosynthetic process
                     from pyruvate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="HGR0392878.1"
                     /translation="MADDKLRATPAARKLADDLGINLYDVSGSGANGRVHKEDVETYK
                     DTNVVRISPLAKRIALEHNIAWQEIQGTGHRGKIMKKDVLALLPENIENDSIKSPAQI
                     EKVEEVPDNVTPYGEIERIPMTPMRKVIAQRMVESYLTAPTFTLNYEVDMTEMLALRK
                     KVLEPIMEATGKKTTVTDLLSLAVVKTLMKHPYINASLTEDGKTIITHNYVNLAMAVG
                     MDNGLMTPVVYNAEKMSLSELVVAFKDVIGRTLDGKLAPSELQNSTFTISNLGMFGVQ
                     SFGPIINQPNSAILGVSSTIEKPVVVNGEIVIRPIMSLGLTIDHRVVDGMAGAKFMKD
                     LKELIETPISMLI"
     gene            10341..12044
                     /gene="lpdA"
                     /locus_tag="ACL3EZ_001315"
     CDS             10341..12044
                     /gene="lpdA"
                     /locus_tag="ACL3EZ_001315"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003001382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004148 - dihydrolipoyl dehydrogenase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HGR0392879.1"
                     /translation="MALEIIMPKAGVDMTEGQIVQWNKKVGEFVKEGEILLEIMTDKV
                     SMELEAEEDGYLIAILKGDGETVPVTEVIGYLGEERENIPTAGAASPEASPVPVASTS
                     NDDGKSDDAFDIVVIGGGPAGYVAAIKAAQLGGKVALVEKSELGGTCLNRGCIPTKTY
                     LHSAEIIENIGHAANRGIVIENPNFTVDMEKLLETKSKVVNTLVGGVAGLLRSYGVAV
                     HKGIGTITKDKNVLVNGSELLETKKIILAGGSKVSKINVPGMESPLVMTSDDILEMNE
                     VPESLVIIGGGVVGIELGQAFMTFGSKVTVIEMMDRIVPAMDVEVSKNLRLILERKGM
                     TILTGTKLQEIIEENGQLRIKVEGKDDIIASKALLSIGRMPDLEGIGEVEFELDRGCI
                     KVNEYMETSVPGIYAPGDINGTKMLAHAAFRMGEVSAENALKGNHAVAKLNLTPAAIY
                     TLPEVAAVGLTEEQAREKYDVAIGKFNFAANGRAIASDAAQGFVKVIADKKYGEILGV
                     HIIGPAAAELINEASSIIEMEITVEEMLKTIHGHPTYSEVMYEAFADVLGMAIHSPKK
                     K"
     gene            12108..13097
                     /locus_tag="ACL3EZ_001316"
     CDS             12108..13097
                     /locus_tag="ACL3EZ_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000873976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HGR0392880.1"
                     /translation="MKYIINHSNDTAFNIALEEYAFKHLLDEDQIFLLWINKPSIIVG
                     RHQNTIEEINRDYVRENGIEVVRRISGGGAVYHDLNNLNYTIISKEDENKAFDFKSFS
                     TPVINTLAQLGVKAEFTGRNDLEIDGKKFCGNAQAYINGRIMHHGCLLFDVDLSVLAN
                     ALKVSKDKFESKGVKSVRARVTNIINELPKKITVEKFRDLLLEYMKKEYPEMTEYVFS
                     EEELAEINRIKDTKFGTWDWNYGKSPEFNVRRGTKFTSGKVEVFANVTESKIQDIKIY
                     GDFFGIEDVAAVEAVLRGVKYEREDVLKALKTIDITRYFAGISREEIAEAVVG"
     gene            complement(13170..14240)
                     /gene="xerS"
                     /locus_tag="ACL3EZ_001317"
     CDS             complement(13170..14240)
                     /gene="xerS"
                     /locus_tag="ACL3EZ_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000817875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HGR0392881.1"
                     /translation="MKREILLERIDKLKQLMPWYVLEYYQSKLAVPYSFTTLYEYLKE
                     YDRFFSWVLESGISNADKISDIPLSVLENMSKKDMESFILYLRERPLLNANTTKQGVS
                     QTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLAARAENIKQK
                     LFLGDETEGFLTYIDQEHPQQLSNRALSSFNKNKERDLAIIALLLASGVRLSEAVNLD
                     LRDLNLKMMVIDVTRKGGKRDSVNVAAFAKPYLENYLAIRNQRYKTEKTDTALFLTLY
                     RGVPNRIDASSVEKMVAKYSEDFKVRVTPHKLRHTLATRLYDATKSQVLVSHQLGHAS
                     TQVTDLYTHIVSDEQKNALDSL"
     gene            complement(14824..16374)
                     /locus_tag="ACL3EZ_001318"
     CDS             complement(14824..16374)
                     /locus_tag="ACL3EZ_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005247 - voltage-gated chloride channel
                     activity [Evidence IEA];
                     GO_process: GO:0006821 - chloride transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HGR0392882.1"
                     /translation="MEEQSEIVRSKKEFAFASSTILSQVGRGIIVGLIVGIIVGSFRF
                     LIEKGFHLIQGVYQDQGYLVRNLFVLVLFYILICWLSAKLTRSEKDIKGSGIPQVEAE
                     LKGLMSLNWWGILWKKYVLGILAIASGLMLGREGPSIQLGAVGGKGIAKWLKSSPVEE
                     RSLIASGAAAGLAAAFNAPIAALLFVVEEVYHHFSRFFWVSTLAASIVANFVSLLMFG
                     LTPVLDMPDNIPPMTLDQYWIYLVMGIFLGFSGFLYEKAVLNVGRVYDLIGQKIHLDR
                     AYYPILAFILIIPVGIFLPQIIGGGNQLVLSLTEQNFSFQVLLAYFLIRFIWSMISYG
                     SGLPGGIFLPILALGSLLGALVGVICVNLGLVSQEQFPIFVILGMSGYFGAISKAPLT
                     AMILVTEMVGDIRNLMPLGLVTLVSYIIMDLLKGTPVYEAMLEKMLPEEVSSEGEVTL
                     IEIPVSDKIAGKQVHELNLPHNVLITTQVHNGKSQTVNGSTRMYLGDMIHLVIPKSEI
                     GKVKDLLL"
     gene            complement(16390..17169)
                     /locus_tag="ACL3EZ_001319"
     CDS             complement(16390..17169)
                     /locus_tag="ACL3EZ_001319"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HGR0392883.1"
                     /translation="MATIKEIKEFLVTVKELESPIFLELEKDNRSGVQKEISKRKRAI
                     QAELDENLRLESMLSYEKELYKQGLTLIVGIDEVGRGPLAGPVVAAAVILPKNCKIKG
                     LNDSKKIPKKKHLEIFQAVQDQALSIGIGIIDNQVIDQVNIYEATKLAMQEAISRLSP
                     QPEHLLIDAMKLDLPISQTSIIKGDANSLSIAAASIVAKVTRDELMKEYDQQFPGYDF
                     ATNAGYGTAKHLEGLTKLGVTPIHRTSFEPVKSLVLGKKES"
     gene            complement(17156..18007)
                     /gene="ylqF"
                     /locus_tag="ACL3EZ_001320"
     CDS             complement(17156..18007)
                     /gene="ylqF"
                     /locus_tag="ACL3EZ_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HGR0392884.1"
                     /translation="MATIQWFPGHMSKARRQVQENLKFVDFVTILVDARLPLSSQNPM
                     LTKIVGDKPKLLILNKADLADPAMTKEWRQYFESQGIQTLAINSKEQVTVKVVTDAAK
                     KLMADKIARQKERGIQIETLRTMIIGIPNAGKSTLMNRLAGKKIAVVGNKPGVTKGQQ
                     WLKTNKDLEILDTPGILWPKFEDETVALKLALTGAIKDQLLPMDEVTIFGINYFKEHY
                     PEKLAERFKQMKIEEEAPVIIMDMTRALGFRDDYDRFYSLFVKEVRDGKLGNYTLDTL
                     EDLDGND"
     gene            complement(18261..23474)
                     /gene="zmpD"
                     /locus_tag="ACL3EZ_001321"
     CDS             complement(18261..23474)
                     /gene="zmpD"
                     /locus_tag="ACL3EZ_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000054791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease D"
                     /protein_id="HGR0392885.1"
                     /translation="MSLLKKDKFSIRKIKGIVGSVFLGSLLFAPSVVGASTYHYLDYS
                     SLTQTERDQLKQGRPDESKESYALDYEKDALPNTGSSQSIMTALGLLAIGSLIVIITK
                     DNRNKKIATFLIVGATGLVTLSTASALNLNANIHESGRDGVLQISGYRYVGYLELDDK
                     TVSSVSPASTVSPVEQPKVVTEKGEPEVHEKPDYTQPIGANLVEPEVHEKLAYTEPVG
                     TTGLDENGNLIEPPVNDIPEYTEPVGTTGVDENGNLIEPPVSDIPEYTEPISTVSEVA
                     SEREELPSLHTDIRTETIPKTTIEESDPSKFIGDDSVRQVGEDGERQIVTSYEELHGK
                     KISDPVETVTILKEMKPKILVKGTKEKPKEKTAPVLTLDRTNTNVLNRSATLSYHLVN
                     TDGVTINKITATIKDGNEIVKTVDLTSEQLDKQVEDLKFYKDYKIETTMTYDRGKGEE
                     TATLEEKPLRLDLKKVEIKNIASTNLVKVNDDGTETPSDFMTEKPSDEDVKKMYLKIT
                     SRDNKVTRLAVDKIEEVTEEGKKLYKITAEAQDLIQHTDPTKVRNKYVHYIEKPVPKV
                     DDVYYNFKELVDAMNADKNGTFKIGADLNATNVPTPNKQYVPGTFKGHLSSVDGKQYT
                     IHNIARPLFDRVENGSVKNINLGNVDINMPWADGIAPVANMVKNATVEDVKVTGNVVA
                     NNNIAGIVNKIDSGGQLTNVAFIGNLTGVGDKGQYMAGIAGEIWRGNLAKAYVEADIV
                     ANRARIGGLVAKTDNGNDSMGIGKYGSIRKSVTKGTIKTKVLFETGGFINSNLPFGKL
                     EDNISMMRVENGEEFFGSSDLDYDGGYFTNGWLERNFVVKGVSSGKHSYKRSRDKIKE
                     ISQDEANKRIANFGLTADKYEINEPVVNRLNRLTRREDEYKSTQDYKSERDLAYRNIE
                     KLQPFYNKEWIVNQGNKLAEDSNLAKKEVLSVTGMKDGQFVTDLSDIDKIMVHYADGT
                     KEEMDVTKNTDSKVQQVREYSVSGLGDVVYTPNMVVKNRDKLIADVKSQLSSVELISQ
                     EVRDLMSRRDKPAENTDERKNGYIKDLYLEESFAEVKQNLDKLVKSLVENEDHQLNGD
                     EAAIKSLLKKVETNKAKIMMALTYLNRYYDIKYGDISIKNIMMFKPDFYGKTPSVIDR
                     LINIGSSEKNLKGDRTQDAYREIIAGNTGKSNLRNFLEYNMRLFTEDKDINDWFIHSA
                     KNVYVSEPKTTNTELKDKRHRVFDGLDNGVHGRMILPLLTLKDAHMFLISTYNTMAYS
                     SFEKYGKHTEEARNEFKTKIDEVAHAQQTYLDFWSRLALPNVRDRLLKSQNMVPTPVW
                     DNQTYNGSPVGRRGFDSKGNPIAPIRELYGPTWRHHDRDWRMGAMASIFPNPNNDDKV
                     LFMVTDMISPFGISAFTHETTHVNDRMLYFGGHKHRQGTDVEAYAQGMLQTPDSSTTN
                     GEYGALGINMAYHRPNDGNQWYNPDPDKLKTRDDIDRYMRNYNEAMMLLDHVEADAVL
                     PKIKGDNSKWFKKIDKEMRSKIQYNDLLGPNQWDSIRDLKDEEKVMTLSSVNDLVDNN
                     FMTKHGNPGNGRYRPEDFTPNSAYVNVNMMAGIYGGNTSQGAPGSLSFKHNAFRMWGY
                     YGYENGFISYVSNKYKAEADKNNHGLLSDKLIINKVSKGNFNTLEEWKRHWYGEVLAK
                     AKKGFEAIDIDGVHISNYDELRPLFDKAVEEDLKKPDDFSHTVALKSKVFKALLKNTD
                     GFFNKLFKEDI"
     gene            complement(23518..29943)
                     /gene="zmpA"
                     /locus_tag="ACL3EZ_001322"
     CDS             complement(23518..29943)
                     /gene="zmpA"
                     /locus_tag="ACL3EZ_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease A"
                     /protein_id="HGR0392886.1"
                     /translation="MEKYFGEKQERFSFRKLSVGLVSATISSLFFMSVLASSSVDAQE
                     TAGVHYKYVADSELSSEEKKQLVYDIPTYVENDDETYYLVYKLNSQNQLAELPNTGSK
                     NERQALVAGASLAALGILIFAVSKKKVKNKTVLHLVLVAGMGNGVLVSVHALENHLLL
                     NYNTDYELTSGEKLPLPKEISGYTYIGYIKEGKTTSDFEVSNQEKSAATPTKQQKVDY
                     NVTPNFVDHPSTVQAIQEQTPVSSTKPTEVQVVEKPFSTELINPRKEEKQSSDSQEQL
                     AEHKNLETKKEEKISPKEKTGVNTLNPQDEVLSGQLNKPELLYRDETIETKIDFQEEI
                     QENPDLAEGTVRVKQEGALGKKVEIVRIFSVNNEEVSREIISTSTTAPVSRIVEKGTK
                     KAQVIKEQAETGAEHKEVQSGAIVEPAIQPELPAAVLTDKGESAVQPELPEAVVSDKG
                     VPEVQPALPEAVMTDKGDPEQVEPLPEYTGVQAGAIVEPEQVAPLPEYTGVQAGAIVE
                     PEKVEAPKEYTGVQAGAIVEPEKVEAPKEYTGVQAGAIVEPEKVEPSKEYTGVQAGAI
                     VEPEQIAPLPEYTGVQAGAIVEPEKVEALKEYTGKIEQPSAEDTKPNNENTNTPEEMS
                     IQKKSSALINMNFITDSSKVTGVGSATFIAPNVLLTVAHNFINNSTDNTTGEFRGDKS
                     KNVYEWVTPDGQKGTFTANNIHFYNKKDYPKGFIYDLAVIKLPETTGREHVELVKNYS
                     KVNLNDKLNVHGYPAGKYTHLKDATVEMEQEYANNTYGVQYQGGNPGMSGGGIFNANG
                     EVIGVHQNGAQNRSGGLILSPTQLAWIKSIIAGNEIPPVYDELYRHKDEKKDDAKDEK
                     EVIKKLELRNISSVELYSKDGNKYRHVTSLASLPSNAENYFMKVKSENFKDVMLPVTS
                     ITNDTKDNRDVYKIVASANSLIQHENNNVLENYTYYLPKTQQSETGVYTSFKNLVDAM
                     NSNPNGTFRLGATMDAREVELPDGQESYVNNVFHGILVGTNNEKYYAIYNLKKPLFGE
                     LNGATVEKLSLKDVNISAKDDTATLAKEANNNTHIDNVHADGAIAGERSIGGLVSQVN
                     NSTISNSSYTGRITNTYKTVASYQIGGLVGKLSGPRGLIDKSFASIDLSSNATQGDQS
                     IGGIVGAVENSALISNSYAEGNLNNVQRFANVGGVVGNLWDPVGGLEKSGRLSNVLSD
                     VNVTNGNAIAGYNFNGIKANGTYSNKNNKVVNVVQEDDEILTKDSTVQRGEVLEDAQI
                     KEKKATFVSKNTIKTEDFNFSSRYVTDYKNLENADSSKEKVYKNIEKLLPFYNRETIV
                     KYGNLVETSSNLYNKELLSVVPMKDKEVISDINKNKSSINKLLLYYADNTSETLNVNY
                     QTDFSNVAEYRIGGTNLIYTPNTLLRNYQNILDEVLPALNSVEYKSEAIRKVLDVSKD
                     VSLTELYLEEQFNTTKTNLKDSLTKLLTADAAIAENNNKVIDNYVIEKIKNNKEALLL
                     GLTYLERWYDFKYRDTKAKDLVMYHLDFFGKSNSSALDNVIELGKSGYNNLLAKNNVI
                     TYNVLLAKNYKTNNLFDALEKYRKAFVPDKTNNEWFKEQTKAYIVEEKSTIKEVSDKQ
                     SIAGSPYSIGVYDRLTSPSWKYPSMVLPLLTLPEKSVFIIANISTIGFGAYDRYRSKE
                     HPAGTDLNDYVEKKAKEAAVRFRDHYDYWYRILDDKNKEKLYRSVLVYDAFRFGTDEK
                     EDKDTYQATFETNHPAIKHFFGPAGNNVVHNSNGAYATGDAFYYMAYRMLDKDGAVTY
                     THEMTHNSDREIYLGGYGRRNGLGPEFYAKGLLQAPDHPNDPTVTINSILKYDQSEES
                     TRLQVADPTQRFGSVDDLNKYMHNMFDVIYMLEILEGKAVAKLDTNQKYDLLRKIENE
                     YKPDPDGNSVYATNVVRRLKPEELTKLTTFNSLIEHDIITRRGYVDEATYKRNGYYTI
                     NLFSPIYSALSSKIGTPGDLMGRRIAFELLAAKGYKDGMVPYISNQYEKEAKAQGKVI
                     TSYGKQIGLVTDEIVLSKVFNNQYNSWIDFKKDMYKEREDKFGKLNKVSFIDPNGSWA
                     RQQKVTIDNINRLEKMIEDAVKFDAEDEVAKLYPETNSRVLKLKKAIFKAYLDQTGDF
                     RSSIFENKK"
     gene            complement(30152..31330)
                     /locus_tag="ACL3EZ_001323"
     CDS             complement(30152..31330)
                     /locus_tag="ACL3EZ_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0392887.1"
                     /translation="MTLPVRKSLHDAVLQASKADTWEQATKEWNEVSLIFNGIGRSNC
                     VCGNAIKYAYELFNGVTGQRLFPIGSDCVRHFHRLSLDQQLEEEEKLLRKVENLTRKA
                     QKKEKIKVNKSDFDERLLKWLWEKGVFKPNRGNQFAPERDYQLFLEVFQGGSWTKAEP
                     KKKARMEEVLEKCIKPFLLGKSDDQLYLVKLGKEKIDYEQELRIQAEKERKKRDKIAK
                     QYADNLVLAMGPAERAYQDYFGFTETLTQEERKWEKILFGKNRAERAIKAKQYQKELE
                     KDQRIASQDPIERKQKQTWLLNSYFRELPEEKARFSRLLLEYRKSGEVPFSTEYLSDH
                     LIDFFYKMKAFEFEIAPEQVRDFLKKSLQEDHRSSAQGSWIEGILLNCLKPFLERLVI
                     "
     gene            complement(31545..35195)
                     /gene="addA"
                     /locus_tag="ACL3EZ_001324"
     CDS             complement(31545..35195)
                     /gene="addA"
                     /locus_tag="ACL3EZ_001324"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0016818 - hydrolase activity, acting on
                     acid anhydrides, in phosphorus-containing anhydrides
                     [Evidence IEA];
                     GO_process: GO:0000724 - double-strand break repair via
                     homologous recombination [Evidence IEA];
                     GO_process: GO:0006302 - double-strand break repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HGR0392888.1"
                     /translation="MKLIPFLSEEEIQKLQEAEANSSKEQKKTAEQIEAIYTSGQNIL
                     VSASAGSGKTFVMVERILDQLARGVEISQLFISTFTVKAATELKERLEKKISKKIQET
                     DDVDLKQHLGCQLADLPNAAIGTMDSFTQKFLGKHGYLLDIAPNFRILQNQSEQLLLE
                     NEVFHEVFEAHYQGKQKESFSHLLKNFAGRGKDERGLRQQVYKIYDFLQSTSNPQKWL
                     SESFLKGFEKADFTSEKEKLTEQIKQALWDLESFFRYHLDNDAKEFAKAAYLENVQLI
                     LDEIGSLNQEFDSQAYQAVLARVVAISKEKNGRALTNASRKADLKPLADAYNEERKTQ
                     FTKLGQLSDQITILDYQERYHGDTWKLAKTFQSFMSDFVEAYRQRKRQENAFEFADIS
                     HYTIEILENFPQVRESYQERFHEVMVDEYQDTNHIQERMLELLSNGHNRFMVGDIKQS
                     IYRFRQADPQIFNEKFQRYAQNPQEGKLILLKENFRSSSEVLSATNDVFERLMDQEVG
                     EINYDNMHQLVFANTKLTPNPDNKAEFLLYDKDDTGEEEESQTETKLTGEMRLVIKEI
                     LKLHQEKGVAFKEIALLTSSRSRNDQILLALSEYGIPVKTDGEQNNYLQSLEVQVMLD
                     TLRVIHNPLQDYALVALMKSPMFGFDEDELARLSLQKAEDKVHENLYEKLVNAQKMAS
                     SQKGLIHTALAEKLKQFMDILASWRLYAKTHSLYDLIWKIYNDRFYYDYVGALPNGPA
                     RQANLYALALRADQFEKSNFKGLSRFIRMIDQVLEAQHDLASVAVAPPKDAVELMTIH
                     KSKGLEFPYVFILNMDQDFNKQDSMSEVILSRQNGLGVKYIAKMETGAVEDHYPKTIK
                     LSIPSLTYRQNEEELQLASYSEQMRLLYVAMTRAEKKLYLVGKGSREKLEVKQYPAAK
                     NGKLNSNTRLQARNFQDWLWAISKVFTKDKLNFSYRFIGEDQLTREAIGELETKSPLQ
                     DSSQADNRQSDTIKEALEMLKEVEVYNTLHRAAIELPSVQTPSQIKKFYEPVMDMEGV
                     EIAGQGQSVGKKISFDLPDFSTKEKVTGAEIGSATHELMQRIDLSQQLTLASLTETLK
                     QVQTSQAVRDKINLDKILAFFDTVLGQEILANTDHLYREQPFSMLKRDQKSQEDFVVR
                     GILDGYLLYENKIVLFDYKTDRYDEPSQLVDRYRGQLALYEEALSRAYSIENIEKYLI
                     LLGKDEVQVVKV"
     gene            complement(35192..38467)
                     /gene="rexB"
                     /locus_tag="ACL3EZ_001325"
     CDS             complement(35192..38467)
                     /gene="rexB"
                     /locus_tag="ACL3EZ_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA];
                     GO_process: GO:0000724 - double-strand break repair via
                     homologous recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent nuclease subunit B"
                     /protein_id="HGR0392889.1"
                     /translation="MKLLYTDIRTSLTEILTREAEELVAAGKRVFYIAPNSLSFEKER
                     AVLECLSQQASFSITVTRFAQMARYLVLNDLPAKTTLDDIGLGLAFYKCLAELDPKDL
                     RVYGAIKQDPQLIQQLIELYHEMTKSQMNFLDLENLTDEDKRADLLLIFEKVTAYLNQ
                     GQLAQGSQLSHLIEAIENDKVSSDFNQIALVIDGFTRFSAEEERVVDLLHGKGAEIVI
                     GAYASKKAYTSPFSEGNLYQASVKFLHHLASKYQTPAQDCSQTHEKMDSFDKASRLLE
                     SSYDFSELALDVDEKDRENLQIWSCLTQKEELELVARSIRQKLHENSDLSYKHFRILL
                     GDVASYQLSLKTIFDQYQIPFYLGRSEAMAHHPLTQFVESILALKRYRFRQEDLINLL
                     RTDLYIDLSQSDIDAFEQYIRYLGINGLPAFQQTFTKSHHGKFNLERLNVLRLRILAP
                     LETLFASRKQKAENLLQKWSVFLKEGAVTKQLQDLTTTLEAVEQERQAEVWKAFCHVL
                     EQFATVFAGSQVSLEDFLALLHSGMSLSQYRTIPATVDTVLVQSYDLIAPLTADFVYA
                     IGLTQDNLPKISQNTSLLTDEERKNLNQTTEEGVQLLIASSENLKKNRYTMLSLVNSA
                     RKQLFLSAPSLFNESESKESAYLQELIHFGFRRREKRMNHKGLSKEDMGSYHSLLSSL
                     VAYHQQGEMSDTEQDLTFVKVLSRVIGKKLDLQGLENPAIPTSPSSKTLAKDTLQALY
                     PAKQEFYLSTSGLTEFYRNEYSYFLRYVLGLQEELRLRPDARSHGNFLHRIFERALQL
                     PNEDSFDQRLEQAIQETSQEREFEAIYQESLEAQFTKEVLLDVARTTGHILRHNPAIE
                     TIKEEANFGGKDQAFIQLDNGRSVFVRGKVDRIDRLKANGAIGVVDYKSSLTQFQFPH
                     FFNGLNSQLPTYLAALKREGEQNFFGAMYLEMAEPVQSLMAVKSLAGAVVEASKSMKY
                     QGLFLEKESSYLGEFYNKNKANQLTDEEFQLLLDYNAYLYKKAAEKILAGRFAINPYT
                     ENGRSIAPYVQQHQAITGFEANYHLGQARFLEKLDLADGKRLVGEKLKQAWFEKIREE
                     LNR"
     gene            complement(38667..38822)
                     /locus_tag="ACL3EZ_001326"
                     /pseudo
     CDS             complement(38667..38822)
                     /locus_tag="ACL3EZ_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
BASE COUNT        11233 a         7621 c         7452 g        12662 t
ORIGIN      
        1 cttcttctcg gaacgaaaga taataacact atttcagcag aagtagatag tctcttggct
       61 ttattaaagg agagtaagta aaggtagcag cattttctaa ctcctaaaaa caggatagga
      121 gaacgggaaa acgaaaaatg agagcagaat gtgagttcta gttctcattt ttttcatgaa
      181 aatgtgcaaa atatagtaga ttgaaactag aatagtatac ctctacttct aaaacattgt
      241 tagaaatcga tttgactgtc ctgttcttat tttactatat cttaacagat agtgtaaata
      301 aagataaact atttactggc taattaatca gttaaacact agttaaggag taatgatgaa
      361 aaaaagaaca atactattat tgatgaccag tctgttggct cttgtcttag gagcatatgg
      421 tttcttggac atattgatcc tggatcattc tcatcaggat tactctttac tgctatttta
      481 gaaactgggg tggtttgatg gaaagtattg gtattggtct tgttatcgtt tcacattcca
      541 aacacattgc agaaggtgtt gttgaactga ttagtaaagt agctaaagat gttccgatta
      601 cttatgtagg aggaaccgag ggcggaggaa ttggaacgag ttttgatcaa gtagataggg
      661 ttgtttccga aaatccagca gatactttac ttgccttttt tgacctaggt tctgctaaaa
      721 tgaacttaaa aatggtgact gatttcagtg ataaaagtat catcatcaac agggttccaa
      781 ttgtagaagg tgcctataat gcagctgctc ttctgcaggc tggtgcagaa ctgtcagtta
      841 ttcaaacaca gttagcggag cttgaaatca ataaataagg aattttacta taactctttt
      901 tataggtaag ctattgatta tctcaactat aaaatgttaa gtaaatgatt tcaaaattag
      961 aaagggattg ctttatgcag ttccttttta ttttaacagg agtgaaacta tagtgtttct
     1021 aaattgtgaa tcaatcaaaa ctgattgtga tggggctatt ctagctttag aatccttcaa
     1081 aaattaaaat ttaaggcaat caattacttg gaagagtatg aaagcattta gtttatagga
     1141 attctaggtc tagaattaca catatattta tgaagacggg ggtgctcgat agttagtatt
     1201 gttctattct gaaagatttg agctgtcagt tgtatagaaa gtgttcgaat tttttttaag
     1261 tgattaaatt agttaattgt atgaggtgct ttatgatata atgttcttaa tgaattttca
     1321 gaaaggaaaa cctcaaattg ttctacaaat ttctactctt cgacctcgac cacactcttc
     1381 ttgattttga tgctgctgag gatgtggctt tgacccaact tctaaaagaa gaaggagttg
     1441 cggatattca ggcttataaa gattattacg ttcctatgaa caaggctctc tggaaagact
     1501 tggagctgaa gaaaatcagt aaacaagagc tggttaacac gcgcttttct cgtttatttt
     1561 ctcattttgg acaggaaaaa gacggtagtt ttcttgccca gcgttaccaa ttttacctcg
     1621 cccagcaggg acaaacacta tcgggcgctc atgatctctt ggacagcctc attgagcgtg
     1681 attatgactt gtatgctgcg acaaatggca ttactgccat tcagacagga cgtttggctc
     1741 aatctggtct agcaccttat ttcaatcaag tctttatctc agaacagttg caaactcaaa
     1801 agccggatgc tctcttttat gaaaagattg gccagcaaat tgctggattt agtaaagaaa
     1861 agacgctgat gattggagat tctctaaccg ccgacattca aggtggcaat aatgcgggga
     1921 ttgacactat ctggtataat cctcatcacc tcgaaaatca cacacaagcc cagccgactt
     1981 acgaagtcta ttcttaccaa gacttgctgg attgtttaga taaaaatatt cttgaaaaga
     2041 tcacatttta aaggagatta gctaatgact acaaaaaaag ctaatattac tattgaagag
     2101 tacattgaaa tgtctgaagt tgattttaat gaagctgtta attatgaatt tacatctgac
     2161 acttgtcaat tagcaaatag tatttatcaa tctcttttta agttttttga taagaaaaat
     2221 ttctctggcg atttaatttt tacttggaaa tctccatcat tagtcaaaga aggggattat
     2281 attgggagaa gggattcaca agtagataat cttagagtaa taggaaatat atttccgaat
     2341 tatcttacta atcgaaaata tagcctcaat atgaatcgta atggctgtat gggagatttt
     2401 cctcatgact tttttgatat atacctagat catgtagcaa aatatgccta cgaacaaaaa
     2461 gttaataata ttaaagagta ttatccttta aaaagagcga ttttacacca agagaatgca
     2521 ttgtattttc gattgttttc taattttgac gactttttag aaaaaaatta tttaaagact
     2581 atatggcaag tttctaaaga aactcctttt tctgaaatgg attttaatat atttaaaaat
     2641 atttcagaaa agataatctt cgaaagaggt agtaaaatgc ttaatgattt aaaaagtaat
     2701 tataaaaaat agccagtctt tataaactgt attcacgtat tcaaatcgta tatatagtcg
     2761 atttattaaa tctttagata aactgtaaaa agtggtttcc atagccactt tttgctataa
     2821 tagaggcagt aaaaatgaag gagtcggcta tggaacactc gtcttggcat gctttgatta
     2881 aggcgcaatt acctgagggt tatttcggga aaatcaatca gtttatggag caggtctatt
     2941 ctcaggggat tatttatcca cccaaggaaa aggtttttca ggctctcttg acaacactgc
     3001 ttgaagaagt taaggtggta attctagggc aagaccccta tcacggacca ggtcaagcgc
     3061 agggcttgag tttttctgta cctgactcta tcccagctcc accatccttg caaaatatct
     3121 tgaaagaatt gtcagatgat atcggagtta agaaatctca tgatttgaca gcttgggctg
     3181 agcaaggagt cttgcttctt aatgcttgtt tgactgttcc tgctggacag gccaatggtc
     3241 atgctggtca aatctgggag ccttttactg atgctgtgat tcaggtggtc aatcatctag
     3301 atagaccagt cgtttttgta ctctggggag cttatgcacg taagaagaag gcattagtta
     3361 ccaatcctca tcacttgatt atcgaatcag cccatccaag tcctttgtcg gtttatagag
     3421 gattttgggg ttccaagccc ttttccaagg ccaatgcatt cttaaaagag acaggacaag
     3481 agccaatcga ttggcttaga taaggagaaa atatgcctca gttagcgacg atttgctaca
     3541 ttgataatgg gaaagaactg ctcatgctcc atcgtaataa gaaacccaat gatgtccatg
     3601 aagggaaatg gattggtgtg ggtggtaagc tagagagagg agagacgccc caggaatgcg
     3661 cggcgcgtga aatccttgaa gaaacagggc tcaaagccaa gccagttcta aaaggtgtca
     3721 tcacttttcc tgaatttaca ccagatttag actggtacac ctatgttttt aaggtgacgg
     3781 agtttgaggg cgacttgatt gactgcaatg aggggacgct agaatgggtt ccctatgatg
     3841 aggttttgag caagccgact tgggaaggtg accacacctt tgttgagtgg cttttagagg
     3901 ataaaccctt cttttcagcc aagtttgttt atgatgggga taaattgttg gatacccaag
     3961 ttgatttcta tgaataaagg agaaagcaga tgctactaat caaaaatggt cgtgtaatgg
     4021 atcccaagtc tggtttggat caagtttgtg atgtcttagt tcaagatggg aaaattatca
     4081 aaattgcgtc tgagatcacg gaagaaggag cagaaacgat tgatgctact ggtcttgtgg
     4141 ttgctcctgg cttggtcgat attcatgttc atttccgtga acctggtcaa acacataaag
     4201 aagacattca tactggtgcc ctagcagccg ctgcaggtgg ttttactact gtcgtcatga
     4261 tggctaatac cagtccaacc atttcagacg tggagacttt gcaagcagtt ctccagtcag
     4321 ctgccaaaga gaagattaat gtcaagacag ttgcgaccat tactaaaaac tttaatggta
     4381 aaaacttgac tgactttaag gcactcttag aagctggtgc ggttggtttc tctgatgacg
     4441 gtattccgct tgagagcagt aagattgtca aggaagccat ggaggaagcc aaaaaactca
     4501 atacctttat cagccttcat gaggaagatc caggtttgaa cggtgttctt ggctttaatg
     4561 aaaatattgc tagagaacat ttccatatct gcggtgctac tggggtggct gagtacgcta
     4621 tgatggcgcg tgatgtcatg attgcctatg caactaaagc ccatgttcac atccagcatt
     4681 tgtctaagga agaaagtgtt aaagtagtgg agtttgctca ggggttaggt gcagaagtca
     4741 cagcagaagt agcgccacag catttctcta agacagaagc acttctttta acacaaggta
     4801 gcaatgctaa gatgaatcca ccgcttcgtt tggaatcaga ccgtcgtgcc gttatcgaag
     4861 gtctcaaatc aggtgtcatc acagttattg cgactgacca cgcgcctcat catgtagatg
     4921 aaaaaaatgt tgaggatatt accaaagcgc catctggtat gactggctta gaaacatccc
     4981 tgtctctcag cttgacctat ttagtagaag ctggtgagtt gagcttgatg gaattacttg
     5041 aaaaaatgac atacaaccca gccaagcttt acaactttga agcaggttac ttggctgaga
     5101 atggtccagc agatatcact atttttgatg ccaaggctga ccgctttgtg gactcccatt
     5161 ttgcttccaa agcagctaat tcaccattca tcggtgaaac cttaaaaggg caggttaaat
     5221 ataccatctg taagggacaa atcgtctatc aagcttgata ggagttagaa tatgaattat
     5281 tttcgaaaac gtagggagag acaagcgaaa tctaatagtg gaatttactg tcccgcagct
     5341 aatcgttcca aaattcaata tgaaactaaa gaaaaagctg accatgcggt tcaatatgat
     5401 aacggaggtt tagttagaag ctattattgt cgtacatgtg cgtgttggca tactacttca
     5461 aaatctaata aacctccgct aagtttgaaa aactatggtc tgaaactctt tggtttagat
     5521 aaatcagaat agaaagagaa gtatgtataa gacaaagtgt ttacgagaga agttagtatt
     5581 atttttaaaa attttcttcc caatcctgat ctaccaattt gccaattatt ctgcctcttt
     5641 tgttgatact gcaatgacag gtcaatacaa cactatggac ttggctggtg tatctatggc
     5701 aaccagtatc tggaatcctt tctttacatt tctaacaggg attgtgtcag ccttggtgcc
     5761 tatcattggt caccatcttg gtcgaggcaa aaaggaagaa gttgcgtctg atttttacca
     5821 atttatttat ttggccttgg gcctatctgt ggtcttgctg gggatggtac ttttcttggc
     5881 accaataatc ttgaatcata ttgggttaga agcagcagta gcggcagtag cggttcgcta
     5941 tctttggttt ttatctatcg ggattatccc cttgttgctc tttagcgtca ttcgttcctt
     6001 gctggattcg ctgggcttga ccaaactgtc catgtacctc atgcttttgt tactccctct
     6061 caatagcgga tttaactatc tcttgattta cggtgccttt ggtgttccag aactgggagg
     6121 ggctggtgct ggtttaggaa catccttggc ctactgggtc ttgcttggga tttctgttct
     6181 ggttttattt aaacaggaga agctcaaagc cttacacctt gagaaacgaa ttccacttaa
     6241 tatggataac attaaggaag gagttcgttt aggtctgcct attgggggaa ctgtcttcgc
     6301 ggaagtggct atcttttcag tggttggctt gattatggct aagttttcgt ccttgattat
     6361 agctagtcac cagtcagcta tgaacttttc aagtcttatg tacgcctttc ctatgagtat
     6421 ctcatcggct atggctattg tcgtttccta tgaagtggga gccaagcgat ttgatgatgc
     6481 gaaaacctat attggtctag gaagatggac tgctctcatt tttgcggcct tcaccctaac
     6541 cttcctttac atttttaggg gaaatgtggc cagtctttat ggtaacgacc caaaatttat
     6601 cgatttgaca gcgcgttttt taacttatag tcttttcttc cagttagcag atacctttgc
     6661 ggcaccgctt cagggaattt tgcgggggta taaggataca gttattcctt tttaccttgg
     6721 tttgcttggt tattggggcg tagcaatccc tgtggctacg ctatttgatt ccctaacaga
     6781 ttttggagct tattcttact ggatcggctt gattattagt ttgattgtga gtggggcgct
     6841 ctaccgttgg cgtttaactg tgattatgaa gagatttgaa tctttagcaa aatccaaacg
     6901 ctaaaaagtt tgtgaaaaaa tattcttgac aagaaaatcc cttgttttca cggggttttc
     6961 ttttttattt tgtgaaattt cttttagaaa aactttgaca gtatttgcca aaagcggtaa
     7021 aatagtaagg taagaagaaa gttagaaagg caagaagatg tcaactttag ataaaaatct
     7081 tttgctagaa atgttccgta agatggaaga aatccgtcgc atggacttaa aaattgcaca
     7141 attagtaaag aaagggaaag tgccaggaat gacgcacttt tctgttggtg aagaggcagc
     7201 taacgtgggg gctatgttag ctctcaatcc agatgatctg attacctcaa accaccgtgg
     7261 acacgggcaa gctattgcta aagggattga cctcaacgga atgatggctg aaatccttgg
     7321 taaatacact ggaacctgta aagggaaagg tggatctatg catatcgctg accttgatgc
     7381 tgggaacctt ggtgccaatg gtatcgtagg tggtggtatg gggatcgctg tcggtgcagc
     7441 cctcagtcag caaatgcaaa ataccggtaa aatcgttgtc tgcttctttg gagatggtgc
     7501 gaccaatgaa ggtgttttcc acgaagcagt gaacatggct tctatctgga acctgccagt
     7561 cattttctat tgcattaaca acggttacgg tatctctgcg gatatcaaga aaatgaccaa
     7621 tatagaacat atccatcaac gtagcgccgc ttatggaatt cctggaatgt tcatcgaaga
     7681 tggtaacaat gtcatcgatg tctatgaagg atttcagaaa gctgtggacc atgttcgcag
     7741 tagcaatggt tcagtcttga ttgaaagtgt aacttatcgc tggctcggtc actcatcatc
     7801 tgaccctggt aaatatcgta cgcgtgaaga agtggaattg tggaaacaaa aagatccaat
     7861 cgaaaacctc cgcaattacc ttattgaaaa taacattgca agtgccgaag aattggaaga
     7921 aatccaagcg caagtaaagg aagcagtaga agcttctgtt aaatttgcag aggaaagccc
     7981 attcccaccg cttgaatcag cctttgaaga tatttacgca gactaaggag aaagagataa
     8041 aatggaaaca aaaacaatgt ccttccgtga caccattatc cttgctatgt ctgaggaaat
     8101 gcgtcgcgat gaaaatgtgt tcttgatggg agaagatgtc ggtgtcttcg gaggagactt
     8161 cggtacttct gttggaatgc ttgaagaatt tggtccagaa cgtgtccgtg actgtccgat
     8221 ttctgaagct gccatctctg gagcagcagc aggagcagcc atgacaggac ttcgtccaat
     8281 cgtcgatatg accttcatgg acttctctgt tattgccatg gacaatatcg tcaaccaagc
     8341 tgctaaaaca cgttacatgt ttggtggtaa aggtcaggtt ccaatgactg ttcgttgtgc
     8401 agctggtaac ggagttggct ctgccgccca gcactcacaa tctctagagt cttggtttac
     8461 tcacattcca ggacttaagg ttgtggcacc tggaacacct gcggacatga aaggcctgct
     8521 taagtcttct atccgtgata acaacccagt tattatactt gagtacaagt cagaatttaa
     8581 ccaaaaaggg gaagtgccag ttgatccaga ctacacaatt ccacttgggg ttggtgaaat
     8641 caaacgccaa ggaacggatg taacagttgt tacttatgga aaaatgcttc gccgtgtggt
     8701 tcaagctgct gaagaattag cagaagaaga aatttcagtt gaaattgttg acccacgtac
     8761 ccttgttccg cttgataagg atatcatcat aaactcagtg aagaagactg gtaaggttat
     8821 tctggtcaac gatgcccaca aaacaagtgg ctatatcggt gaaatttcag ctattatttc
     8881 agaatcagaa gcatttgact atctagatgc accaatacgc cgttgttcag gagaagatgt
     8941 gccgatgcct tatgcacaaa acctagaaaa tgcaatgatt ccaacagttg aaagtatcaa
     9001 agatgcaatc cgaaaaactt ataacaaaga ctagagttac ataatataag ttatgtaact
     9061 aaaataaagc tgacgagaaa ctttgtatct tttaggtgca gagctcttcg tcattaatat
     9121 cttatattcg agcacgggct aaaagctcgg aaaaaagata aatctccttg gcttcatcga
     9181 agccatcgtc gatttcctat ttttcagtcg cttttgacgc cctttgtatc ataaatagaa
     9241 ttggagaggt catggctgat gacaagctaa gagcgactcc tgcagctaga aagttagcgg
     9301 atgatttagg gataaacctc tacgacgttt ctggctcagg tgcaaacggt cgtgtccaca
     9361 aagaagacgt ggaaacttat aaagacacaa acgtggttcg catttcgcca cttgcaaaac
     9421 gaattgccct cgaacataac attgcttggc aggaaatcca aggaaccggt catcgtggta
     9481 aaatcatgaa gaaggatgtt ttggccctgc ttcctgaaaa tatcgaaaac gatagcatca
     9541 aatctcctgc tcagattgaa aaagtggaag aagtccctga taacgtaaca ccatatggtg
     9601 aaatcgagcg tattccaatg acaccaatgc gtaaggttat tgcccaacgc atggttgaat
     9661 cttacttgac tgcgccaacc ttcaccctca actatgaagt tgatatgact gaaatgttgg
     9721 ctcttcgtaa gaaggttctt gagccaatca tggaagcaac tgggaagaag actactgtaa
     9781 cagaccttct ttcgcttgca gttgttaaga ctcttatgaa acacccatac atcaacgctt
     9841 cattgacaga agatggcaag actattatca ctcacaacta tgtcaatctt gccatggcag
     9901 ttgggatgga taatggattg atgacacctg ttgtttacaa tgctgagaag atgagtcttt
     9961 cagaactggt ggtagccttt aaggatgtta ttggccgtac cttggatggt aaattggctc
    10021 caagtgagtt acaaaattca acattcacaa tcagtaattt gggaatgttt ggtgttcagt
    10081 cctttggtcc gattattaac caacccaact cagctatcct tggtgtcagt tcgacaatcg
    10141 agaagccagt tgtcgtcaat ggtgaaattg tgattcgccc aatcatgagt ttaggattaa
    10201 ccattgacca ccgtgtcgta gatggtatgg ctggtgctaa gtttatgaag gacttgaaag
    10261 agttgattga aacgccaatc tcaatgttaa tttaagagca agagtattca tttttaagat
    10321 atagataaag gaaggaagac atggccttag aaataattat gccaaaagcc ggcgtggata
    10381 tgacagaagg acaaatcgtc caatggaata aaaaagtcgg agaatttgta aaagaaggag
    10441 aaatcctttt ggaaatcatg actgataaag tcagcatgga attggaagcc gaagaagatg
    10501 ggtacttgat tgccattctc aaaggagatg gtgaaactgt ccctgtaacg gaagttatcg
    10561 gttaccttgg tgaagaaagg gaaaacatcc caacagctgg agcagcatcg ccagaagcta
    10621 gccctgtacc tgtagcaagt acctcaaacg atgatggtaa gagcgatgat gcttttgata
    10681 tcgttgtgat tggtggaggt cctgctggtt atgttgcagc cattaaagct gcccaactcg
    10741 gcggtaaggt tgcccttgtt gagaaatctg aacttggtgg aacctgctta aaccgtggat
    10801 gtattccaac caagacctac cttcatagcg ctgaaattat tgaaaatatc ggtcatgctg
    10861 caaatcgtgg tatcgtgatt gaaaatccta acttcactgt tgatatggaa aaacttttag
    10921 aaactaaatc taaagttgtt aatactcttg ttggtggtgt tgcaggactt cttcgtagct
    10981 acggagttgc tgttcataaa ggaattggta caatcactaa agacaagaac gtcttggtaa
    11041 atggttctga attgcttgaa accaagaaaa tcattcttgc tggtggttca aaagtcagca
    11101 agatcaacgt ccctggtatg gaatctccac ttgtcatgac tagtgatgac attcttgaaa
    11161 tgaacgaagt gccagaaagc cttgttatca tcggtggtgg agttgtcggt atcgaactcg
    11221 gtcaggcctt catgacattt ggttcaaaag tgactgttat cgaaatgatg gaccgtatag
    11281 ttccagctat ggatgtggaa gtttctaaga accttcgctt gatccttgag cgtaaaggaa
    11341 tgaccatctt gactggtact aaactgcaag aaatcattga ggaaaatggt caacttcgta
    11401 tcaaggttga aggaaaagac gatatcatcg caagcaaagc tcttctttca attggtcgta
    11461 tgccagacct tgaaggtatt ggagaggttg agtttgaatt ggatcgtggt tgtatcaagg
    11521 tcaacgaata catggaaact tcagttccag gcatttatgc accaggtgac atcaacggta
    11581 ctaagatgtt ggctcacgca gctttccgca tgggtgaagt ttccgctgaa aatgccctta
    11641 aaggaaatca tgcagttgcc aaattgaatt tgactcctgc agccatctac actcttcctg
    11701 aagtagcagc agtaggtttg acagaagaac aagcccgtga gaaatacgat gttgccatcg
    11761 gtaagtttaa ctttgctgct aacggtcgtg ctattgcatc tgacgcagct caaggtttcg
    11821 taaaagttat cgctgataag aaatacggag aaatccttgg tgtacacatt attggtcctg
    11881 cagccgcaga attaataaac gaagcatcaa gcatcatcga aatggaaatc actgttgagg
    11941 aaatgctgaa gaccatccac gggcacccaa cttactctga agtgatgtac gaagcgtttg
    12001 cagatgttct aggaatggcc atccattcac ctaagaaaaa ataaaacgaa gatagattag
    12061 actggaaggt tatttccagt ttctatcata taaagtaaag ggatatcatg aaatacatta
    12121 tcaatcattc aaatgacact gcttttaata ttgccttgga agaatacgcc tttaaacacc
    12181 ttttggatga ggatcaaatc ttcctacttt ggattaacaa gccatctatc attgttggtc
    12241 gtcaccagaa cactattgaa gaaatcaacc gtgattatgt tcgcgaaaat ggtattgagg
    12301 tagttcgccg tattagtggt ggtggagctg tttaccacga tttaaataac ctcaactaca
    12361 cgatcatctc caaagaagat gaaaataagg catttgactt caagagcttc tcaactccgg
    12421 ttatcaatac cttggctcaa ctcggggtta aagctgagtt cacaggtcgt aatgaccttg
    12481 agattgatgg taagaagttc tgtggcaatg cccaagccta tatcaacggc cgtatcatgc
    12541 accacggttg cttgctcttt gacgttgatt tgtcagtcct cgcaaatgcc cttaaggttt
    12601 caaaagataa atttgaatca aaaggtgtga aatccgtccg tgcccgtgta accaatatta
    12661 tcaatgaatt accaaaaaaa atcacagtcg aaaaattccg tgatttactc ttggaataca
    12721 tgaaaaaaga gtacccagag atgactgaat acgtcttttc agaagaagaa ttggccgaaa
    12781 tcaatcgcat caaggatact aagtttggaa cttgggactg gaactatggt aaatcacctg
    12841 aatttaacgt ccgtcgtgga accaaattca ctagtggtaa ggttgaagtc tttgctaacg
    12901 ttactgaatc aaaaatccaa gacatcaaga tttatggtga cttctttggt attgaagacg
    12961 ttgctgcagt agaagctgtc cttcgtgggg tgaaatacga acgcgaagat gttcttaagg
    13021 cgctaaaaac cattgatatc acacgctact tcgctggtat tagccgtgaa gaaatcgctg
    13081 aagcggtagt tggataaatc aaaaagaagt tggccaacta accaacttct ttttttgata
    13141 tttatttaca taatttaaaa tacgtaaaat cataaactat ccagagcatt cttttgttca
    13201 tcactaacaa tatgggtata gaggtcagtg acttgtgtgc tagcatgtcc tagttggtga
    13261 ctgactaaaa cttgtgattt agtcgcatca tagagcctag ttgctagtgt atggcgcagt
    13321 ttatggggtg ttacacgcac tttaaaatcc tctgagtatt tagcaaccat tttctcaacg
    13381 ctagaagcat cgatacgatt aggaacacct ctgtagagag ttaaaaaaag ggctgtatct
    13441 gttttttccg ttttatagcg ttgattccga atggccagat aattctctaa ataaggttta
    13501 gcaaaagcag cgacattgac tgagtcacgt ttgccacctt ttcgagtaac atcaataacc
    13561 atcattttta gattgagatc tcttagatct agattaacag cttcagataa gcgaacacca
    13621 gatgccaaga gaagggcaat aatggctaaa tctcgttctt tatttttgtt gaatgatgag
    13681 agagctcgat ttgaaagctg ttgtgggtgc tcttgatcga tataagttag aaaaccttct
    13741 gtttcatcac ctagaaagag tttttgcttg atattttcag ctctggcagc aagggtttct
    13801 ttctttttct tggttgaaac ttttttcatt acattacgat agaaataagg ttccccctga
    13861 tcgttttcaa cctcctcggt tagatacttg taaagactag aaagtgctga taaggttcga
    13921 ttaatagttg tctgtgaaac accttgtttt gttgtattag cattcagcaa gggacgttca
    13981 cgtagataaa ggataaagga ttccatgtct ttcttagaca tattttccaa aactgataaa
    14041 ggaatatcgg atattttatc agcgtttgaa ataccagact ccaaaaccca gctgaaaaat
    14101 cggtcatatt ccttaaggta ttcgtacagg gttgtaaaac tgtagggcac agccagttta
    14161 gattggtagt attccagaac ataccagggc atgagttgtt ttagtttgtc gattcgttcc
    14221 agtaaaatct cacgtttcat gtattttctc cataattaag tatactagta gtatagcata
    14281 gacttgtata tttttcaaga aaattatagt ttttctgaaa gatgttatag gagtttttca
    14341 aagtgataaa aagacttaga cctacaaaca aaacagaata aggaaaataa taaaaatctc
    14401 acccactaaa cttctgttaa tactacataa ctgaagagct atataaggag ctatgagata
    14461 caaaacacat tgtataatag attgaaacta gaatagtaca tctggacttc taaaacattg
    14521 ctagaaattg atttgattgt cctgattgtt ttatcctatt tctatttcat ttctctatat
    14581 aattgctatt gttttctttt tcatgatttt aatcttactg tacagatttg atacagtaaa
    14641 ctcctttcta gctttatact ttatcatttc taacttaatt atagtcttat ttttaataaa
    14701 gttcaattat ttatatgtaa aaatcctcat cagtaaaaaa taaccgatct catttctgag
    14761 aatcggtttt ctaaataaat caaaccgatc atttacataa cataaattat gtaaatgatc
    14821 atactacaac aacaaatctt tgacttttcc aatttcactt tttggaataa ccaggtgaat
    14881 catatcaccc agatacattc tggttgagcc gttaaccgtt tggctcttgc cattatggac
    14941 ttgagttgtg atgaggacgt tgtgtggtaa gttgagttca tgaacttgtt tcccagcaat
    15001 tttatcagaa actggtattt cgataagtgt aacttctcct tcgctagata cttcttctgg
    15061 aagcattttt tccagcatgg cttcatagac tggcgtacct ttgagcaaat ccatgataat
    15121 ataagaaaca agagtgacaa gaccaagtgg cataaggttg cgaatatctc ctaccatctc
    15181 agttacgagg atcatagcgg ttaagggagc ttttgatatg gctccaaaat agccactcat
    15241 tcctagaatg acaaatatag ggaattgctc ttgactgaca agtccaagat tgacacagat
    15301 aacaccaact aaggcaccaa gcaaagaacc aagagctaaa atggggagga aaattcctcc
    15361 tggcagtcca cttccatagc taatcatact ccaaataaag cggattaaaa agtaagctaa
    15421 taaaacttgg aaactaaaat tttgttcagt taaagaaagg acaagctgat ttccgccacc
    15481 aatgatttga ggtaagaaga ttccgactgg tatgataagg ataaaagcca agatgggata
    15541 ataagcccta tccaaatgga ttttttgacc aatcaagtca taaactcttc caacgtttaa
    15601 tacagctttc tcatagagaa aacctgaaaa tccaaggaaa attcccatga cgagatatat
    15661 ccaatactga tctagggtca tgggaggaat gttatctggc atatccaata ctggtgtcaa
    15721 accgaacatg agtagagaca caaagtttgc tacgatgctg gctgctagag ttgagaccca
    15781 gaaaaagcgc gaaaaatggt gatagacttc ttctacaaca aagagaagtg ctgcaatagg
    15841 agcattaaag gctgcggcta aacctgctgc agctccactg gcaatcaagg aacgttcctc
    15901 tactggactg gatttgagcc acttggcaat tcctttacca ccaactgctc caagttgaat
    15961 actgggtccc tctcgaccca gcatgagtcc actggcaata gcaagaatac ctagcacata
    16021 ttttttccaa agaatgcccc accagttgag ggacatgagg cctttcagtt cggcttcgac
    16081 ttgaggaatt cctgagcctt taatatcttt ttctgaccgt gttagtttgg cactgagcca
    16141 acagatgagt atataaaaca aaaccagtac aaaaagattg cgcactaagt acccttgatc
    16201 ttgataaact ccttgtatca ggtggaagcc cttttcaatt aagaaacgaa aggatccgac
    16261 gataattcca acgatgaggc cgacaatgat tcctcgacca acttgggata gtatagtgct
    16321 ggatgcaaag gcgaattctt tcttagaacg gactatttcc gactgttcct ccatggtatt
    16381 tcctttcaat taactttctt ttttacctaa aaccagtgat ttaacgggtt caaagctggt
    16441 tcggtgaatt ggggtaactc ctagttttgt gaggccttcc agatgtttag ctgtgccata
    16501 tcctgcatta gtagcgaaat catagccagg gaactgctga tcgtattcct tcatcaattc
    16561 atcacgtgtt accttggcta ctatagatgc tgctgcgata gagagggagt tggcatctcc
    16621 tttgataatg gaggtttgtg aaatgggcaa gtccagtttc atggcatcaa tcaaaaggtg
    16681 ctctggttga gggctgagcc gggagattgc ttcttgcatg gctagtttgg ttgcttcata
    16741 gatgttgact tggtcgatga cctgattatc tatgatacca attccaatcg acaaggcttg
    16801 gtcttgaacg gcttggaaaa tctccagatg tttcttttta ggaattttct tgctgtcgtt
    16861 gagaccttta atcttacaat ttttaggtaa aatgacggcc gcagcgacta caggaccagc
    16921 aagaggacca cgaccaacct catcaatacc tacaattaag gtcaatcctt gcttataaag
    16981 ttctttttca taagaaagca tggattccaa gcgcaaattt tcatctaatt cagcttgaat
    17041 ggctctttta cgcttgctga tttccttttg aactcctgag cgattatcct tttcaagctc
    17101 taaaaaaata gggctttcta actccttgac tgtcacaagg aattctttga tttctttaat
    17161 cgttgccatc gaggtcttcc aatgtatcta aggtatagtt accgagtttg ccatcacgga
    17221 cttccttcac gaagagactg taaaaacggt catagtcatc acggaaaccg agggcgcggg
    17281 tcatatccat aataatcaca ggcgcttctt cttcaatttt catttgtttg aagcgttcag
    17341 ccagcttttc tggataatgt tctttgaaat aattgatacc aaaaatggta acctcatcca
    17401 taggaagcaa ctgatccttg atagctccag tcaatgccaa cttaagtgca acagtttcat
    17461 cctcaaactt aggccagaga atccccggtg tatccaagat ttccaggtct ttattggttt
    17521 taagccattg ttgacctttt gtgacccctg gcttgtttcc aacaacagca atctttttac
    17581 cagccaaacg gttcatcaga gttgatttac cagcgtttgg aatcccgata atcatagtac
    17641 gcaaggtttc aatctgaatc ccacgttctt tctggcgagc aatcttatca gccatgagct
    17701 tcttggccgc atctgttaca acttttacag tcacttgctc cttggagttg atagccagag
    17761 tttggattcc ttgtgattca aaatactgac gccattcctt ggtcattgct ggatcagcca
    17821 aatccgcctt atttaaaatc aagagttttg gtttatcacc aacaatcttg gtcaacatag
    17881 gattttgact agatagaggt aagcgtgcat ccaccaaaat cgttacaaaa tcaacaaatt
    17941 ttaaattttc ctgcacctgt cgacgcgctt tagacatgtg accaggaaac cattgaatag
    18001 tagccattga gtttttttcc tttcgtagca agggtttaga gatcctattt tattttacta
    18061 tcgtttgaac ataaagggtt ctcaaatgaa tgatgttcaa acagtttttt gttttatgac
    18121 atagaaatct accttatatt atatcatgcc ttctttattt tgtccgatga tagcctttca
    18181 agtaccctat atagaaaaaa gccatcaaat gatgactttt cagagggagc aaaaaactgt
    18241 tccttctata ttctaaacat ttaaatgtct tctttaaaca gtttattaaa gaaaccgtct
    18301 gtgtttttaa gaagggcttt gaagacctta gatttaagag caacagtgtg agagaagtca
    18361 tctggtttct tcaaatcttc ttcaactgct ttatcaaata aaggccttaa ctcatcatag
    18421 ttactgatat ggacgccatc aatatcgata gcctcaaaac ctttcttagc tttagcaaga
    18481 acttccccgt accaatgtct cttccactct tcaagagtat taaagtttcc tttcgatact
    18541 ttattaatta ttagcttatc gcttagtaaa ccgtggttgt ttttatctgc ttctgctttg
    18601 tatttatttg atacataact aataaagcca ttttcataac cataatagcc ccacatacgg
    18661 aaagcattgt gcttaaatga taatgaacca ggagcacctt gactcgtatt cccaccgtaa
    18721 attcctgcca tcatattgac atttacgtaa gctgagtttg gtgtaaaatc ttctggtcta
    18781 taacgtccat tacctggatt tccatgtttt gtcatgaagt tattatccac taaatcattg
    18841 acgctagata aagtcattac cttttcttca tctttcaaat cacggatact atcccattgg
    18901 tttggaccta aaagatcatt atactgaatc ttagagcgca tttctttgtc aatcttcttg
    18961 aaccacttac tattgtctcc tttaatttta ggaagtacag catcagcttc tacatgatca
    19021 agcaacatca tagcttcatt gtagtttctc atgtagcggt caatgtcatc acgtgtcttt
    19081 aatttgtcag gatctgggtt gtaccattgg ttaccatcat ttggacgatg gtaagccatg
    19141 ttaattccaa gtgcgccgta ttcaccatta gtcgttgagc tgtcaggtgt ttgcaacata
    19201 ccttgagcat aggcttcaac gtctgtacct tgacgatgct tatgaccacc gaagtaaagc
    19261 attctatcgt ttacgtgtgt tgtttcgtga gtaaaggctg aaataccaaa tgggctaatc
    19321 atatccgtca ccataaacaa gaccttgtca tcattatttg gattagggaa tattgatgcc
    19381 atagcgccca tacgccagtc tctatcatgg tgtcgccatg ttggaccata taattcacga
    19441 attggagcta tagggttacc tttactgtca aatcctcgac gacctacagg agaaccattg
    19501 taggtctggt tatcccaaac tggtgtcggt accatatttt gactcttaag aagtctatca
    19561 cgaacattag gcagagctaa tctggaccag aaatctaaat aagtttgttg agcatgtgca
    19621 acttcatcaa tcttagtttt gaactcatta cgagcttctt ctgtatgttt tccatatttc
    19681 tcaaatgaac tgtacgccat cgtgttatat gttgaaatta agaacatatg ggcatcttta
    19741 agcgttagaa gtggtaaaat catacgacca tgaacaccgt tatctaaacc atcgaacaca
    19801 cgatgacgtt tatctttcaa ctctgtattt gttgtcttag gttctgaaac ataaacattc
    19861 ttagctgagt ggataaacca atcattgatg tctttatcct ctgtaaacag acgcatgttg
    19921 tattctaaga agttacgcaa attactttta ccagtattac ctgcgatgat ttcacggtaa
    19981 gcatcctgag tccgatcccc tttcaagttc ttttcacttg aaccgatgtt gatgagtctg
    20041 tcaataacac ttggtgtttt accataaaaa tcaggtttga acatcatgat gttttttata
    20101 cttatgtcac cgtatttgat atcatagtaa cgattgagat aagtcagagc catcatgatt
    20161 ttagctttat tggtttccac tttcttgaga agtgatttta tcgcagcttc atcaccattc
    20221 aattgatggt cttcattttc gaccaaggat ttgactaact tatctagatt ttgcttcact
    20281 tcggcaaagc tttcttctaa gtatagatct ttaatataac cattcttacg ttcatccgta
    20341 ttctctgcag gtttatcacg tctactcatt aaatctctta cttcttgtga aatcaattcc
    20401 acacttgata attgagattt aacatcagca atcaatttat cacgattttt aacaaccata
    20461 ttcggtgtat aaacaacatc accaagacca gatacactat attcacgcac ttgttggact
    20521 ttagaatcag tattcttagt aacatccatt tcttccttag taccatcagc atagtgaacc
    20581 ataatcttat caatatctga taaatcggtc acgaattgac catccttcat ccccgtaaca
    20641 gaaaggactt ctttcttagc taagtttgaa tcttctgcaa gtttgttacc ttggttgaca
    20701 atccattctt tattataaaa tggttgaagt ttctcaatat tacgataagc taaatcacgt
    20761 tcggatttgt agtcttgagt tgacttatat tcatcttctc ttctggttaa acgatttaag
    20821 cgattgacca caggttcgtt gatttcgtat ttatcagcag taagtccaaa atttgcaatt
    20881 ctcttattag cttcatcttg actaatttct ttaattttgt cacgagaacg tttgtatgaa
    20941 tgcttacctg aactgacacc tttgacaaca aagttacgct ctaaccagcc atttgtgaaa
    21001 taaccaccat cgtagtccaa atcggaagaa ccaaagaact cttcaccatt ttcaactctc
    21061 atcattgaaa tattatcttc aagtttacca aaaggaagat tgctattgat aaatccacct
    21121 gtttcaaaca aaactttagt cttaatggtt cctttggtga ctgatttacg aattgaaccg
    21181 tatttaccaa ttcccataga gtcgttacca ttatctgttt tagcaactaa accacctata
    21241 cgggctctgt tagcaacaat atcagcctcg acatatgctt ttgcaagatt acctctccaa
    21301 atctcaccgg caatgccagc catatattga cctttatcac caacacctgt aagattaccg
    21361 atgaaggcta catttgtcaa ctgaccacca ctatcgattt tattgacgat acccgcaata
    21421 ttgttattag caactacatt accagttacc ttaacatctt caacagttgc atttttcacc
    21481 atattggcaa caggtgctat tccgtcagcc caaggcatat tgatatccac attacctaaa
    21541 ttaatatttt tcacagaacc attttcaaca cggtcaaata agggacgggc aatgttatga
    21601 attgtatatt gtttaccatc aacacttgat agatgtccct taaacgtacc tggaacatat
    21661 tgtttgttag gtgttggtac attcgttgca ttcaaatctg ctccgatttt aaatgtacca
    21721 tttttatcag cattcatggc atctactaac tctttaaagt tataataaac gtcatcaact
    21781 tttggaactg gtttttcaat ataatgaaca tacttgttac gaaccttcgt tgggtctgta
    21841 tgttgaatca aatcttgagc ttcggcagtg attttataaa gtttcttacc ttcttcagtc
    21901 acttcttcaa ttttatcaac tgctaaacgt gttactttat tatcacgact agtaattttt
    21961 aagtacattt tcttcacatc ttcatctgaa ggtttttcag tcataaaatc actaggtgtt
    22021 tcagtaccat cgtcatttac cttcactaaa ttagtagatg cgatattttt aatttcaact
    22081 tttttcaaat ccaagcgaag tggtttctct tctaatgttg cagtttcttc tcccttgcca
    22141 cggtcatagg tcatagtggt ctctatctta tagtccttgt agaattttaa atcttctacc
    22201 tgcttatcta attgctctga agtcaaatct actgttttga caatttcatt tccatcttta
    22261 attgtcgcag taattttatt gattgtgact ccatctgtat taactaaatg ataagaaaga
    22321 gttgcggatc ggtttaatac atttgtattt gttctatcta aggtcaaaac aggagccgtt
    22381 ttttctttag gtttttcttt ggtacctttt acaagaattt taggcttcat ttctttcaaa
    22441 atagttactg tttcaactgg gtcactgatt tttttgccat gtaactcttc atagctagta
    22501 acaatttgac gttcgccatc ctcaccaact tgtctaacag aatcatcgcc tataaatttg
    22561 ctaggatcag attcttctat agtggtttta ggaatagtct ctgtccgaat atcggtatgt
    22621 aaagaaggca actcttctct ttctgatgca acttctgaaa ctgtagatat tggttcagta
    22681 tactctggaa tgtcgctaac aggtggctca atcaagtttc cattttcatc cactcctgtt
    22741 gtacctactg gctcagtata ttctgggatg tcgttaacag gtggttcaat caagtttcca
    22801 ttttcatcta atcctgttgt ccctactggt tcagtgtatg ctagtttctc atgaacttca
    22861 ggctcaacaa ggtttgcacc tattggttgc gtatagtcag gcttctcatg aacttccggt
    22921 tcgcctttct ctgttacaac tttgggttgc tcaactggcg aaacagttga tgctggagaa
    22981 accgacgaaa cagttttatc atcaagctcc aagtaaccaa catatctgta accagaaatt
    23041 tgcaacacac catcacgtcc agactcatgg atgttagcat tcaaattaag tgctgaagca
    23101 gttgatagtg taactaaacc tgtcgcccct acaatcaaaa atgtagctat ttttttattt
    23161 ctattatctt ttgtgataat cacaataaga ctcccgatag ctaacaaacc caatgcagtc
    23221 ataatagatt gagaacttcc tgtgtttggt agtgcgtctt tttcataatc caaagcatat
    23281 gactctttgg attcatcagg tctaccttgt ttgagttgat cacgttcagt ttgtgtcaaa
    23341 ctactataat ctaagtaatg ataagtcgat gcaccaacaa ctgacggtgc aaataaaaga
    23401 ctccccaaga ataccgaacc aacaataccc tttattttcc gaatggaaaa tttatctttt
    23461 tttaataatg acaattctaa tcctccacct tcacttttta tttcctaata gtaaacacta
    23521 ttttttattc tcaaaaattg aacttctaaa atcaccggtt tggtcaagat aagctttaaa
    23581 gattgctttt ttcagtttaa gaactctact atttgtctca ggatataatt tggcaacttc
    23641 atcctcagca tcaaatttta ctgcatcttc aatcattttt tcaagtctat taatattatc
    23701 aatagtcact ttctgttgtc gagcccaaga accgtttgga tcgataaaac taactttatt
    23761 taactttcca aatttatctt ctctttcttt atacatatct ttcttgaaat ctatccaaga
    23821 attatactgg ttattaaata cttttgaaag aacaatttca tcagtaacta aacctatttg
    23881 tttaccatat gatgtaataa cttttccttg agctttcgct tctttttcat actgattaga
    23941 aatatatgga accataccgt ctttgtaccc cttggctgcc aataactcaa atgcaatacg
    24001 tcgtcccatt aaatctcctg gtgttcctat tttactgctc aatgctgaat aaattggtga
    24061 gaatagatta attgtatagt agccattccg cttataagtt gcttcatcta cataacctct
    24121 tcttgttata atatcatgtt ctatcaaact gttaaatgta gttaatttag taagttcttc
    24181 tggttttaat ctacgtacaa cattcgttgc ataaacagaa tttccatcag gatcaggttt
    24241 atattcattt tctatttttc ttaataaatc atatttttga tttgtatcta atttagctac
    24301 agctttacct tctaatattt caagcatgta tattacatca aacatattat gcatatactt
    24361 atttagatca tcaacacttc caaatcgttg agttggatct gctacttgaa gccttgttga
    24421 ttcttctgat tgatcatatt ttaatatgga attaatagtg actgttggat cattaggatg
    24481 atcaggagct tgtagcagtc ctttagcata aaactctggt ccaagtccat ttcgtcttcc
    24541 atagcctcca agataaattt ctctatctga gttatgtgtc atttcgtgtg tataagttac
    24601 cgcaccatct ttatcaagca tgcgatatgc catataatag aatgcatccc ctgtagcata
    24661 tgctccatta gaattatgaa caacattatt tcccgctgga ccgaagaaat gttttatagc
    24721 tggatgatta gtttcaaaag ttgcttgata tgtatcttta tcttcttttt catctgtacc
    24781 aaatctaaat gcatcataga ctagaacact tctatataat ttttctttat ttttatcatc
    24841 tagtattcta taccaataat catagtgatc tctaaatcta acagccgctt ctttagcttt
    24901 tttctcaaca tagtcattta aatcagttcc tgctggatgt tctttacttc tatatctatc
    24961 ataagcaccg aaacctatag tcgaaatgtt ggctataata aacaccgatt tttcaggtaa
    25021 tgttaatagc ggcaacacca tacttggata tttccaagat gggctagtta atctatcata
    25081 tactccaatt gaatatggac taccagctat tgattgctta tcacttacct ctttaatagt
    25141 agatttttct tctacaatat atgctttagt ttgttcttta aaccactcat tatttgtttt
    25201 atctggtaca aatgcttttc tatatttctc taatgcatca aataaattat tagtcttata
    25261 atttttcgct aataaaacat tataagttat aacattattt tttgctagta agttattata
    25321 tcccgattta cctagttcga taacattatc taacgctgaa ctatttgatt taccgaagaa
    25381 atccaagtgg tacatgacta aatctttcgc ttttgtatca cgatatttga agtcgtacca
    25441 acgctctaag tatgttaatc ctagaagtaa agcttcttta ttatttttaa ttttctcgat
    25501 tacataatta tctattacct tattgttatt ttcagctatt gcagcatctg cagtaagaag
    25561 ttttgtcaaa ctatctttca aattagtttt tgtggtattg aattgttctt ctaaatataa
    25621 ctccgttaaa ctaacatcct tagaaacatc taatactttt ctaattgcct ctgatttata
    25681 ttctacacta tttaatgctg gtaatacttc atctaaaata ttttgataat tgcgaagtaa
    25741 tgtattcggt gtataaatta agtttgtacc gcctattcta tactctgcta catttgaaaa
    25801 atcagtttga taatttacat taagtgtctc tgatgtatta tccgcgtaat atagtaatag
    25861 tttatttata cttgatttat ttttgttaat atcactaatt acttctttat ctttcatagg
    25921 gactactgac aataattctt tattataaag attactactt gtctctacta aatttccgta
    25981 cttaacaatt gtttctctat tataaaacgg taatagtttt tcaatatttt tatatacttt
    26041 ttcttttgat gaatcagcat tctcaagatt tttatagtca gttacatatc tagaagagaa
    26101 attaaaatct tctgttttaa tagtattttt agatacaaaa gtagcttttt tctcttttat
    26161 ttgtgcatct tctaatactt ctcctctttg aacagtagaa tccttagtta agatttcatc
    26221 atcttcttgt actacgttca caaccttatt atttttatta ctgtatgtgc catttgcttt
    26281 tataccatta aaattataac ctgcaatagc attaccattc gttacattaa catcgcttag
    26341 tacattagaa agtcgaccgg atttttctaa tcctccaacc ggatcccaaa gattaccaac
    26401 tactccacca acgtttgcaa aacgttgaac attatttaga tttccttcag cataactatt
    26461 actaataagc gcactatttt ctactgcacc aactattcca ccaatagact ggtctccttg
    26521 tgttgcattt gaagataaat cgattgatgc gaacgactta tctattaatc ccctcggacc
    26581 agaaagtttg cctactaaac ctccgatttg ataactagca actgttttat atgtattagt
    26641 tattctacct gtatagctac tgttagaaat agtagaatta ttaacttgtg atactaatcc
    26701 tcctatgcta cgttccccag ctatcgctcc atcagcatga acgttatcaa tatgagtatt
    26761 gttatttgct tctttcgcaa gtgttgcagt atcgtccttt gcggaaatat taacatcttt
    26821 tagtgaaagt ttttctactg tagcaccatt taattcccca aataatggtt ttttcaaatt
    26881 ataaatagca taatatttct cattatttgt tcctactaat attccatgga atacattatt
    26941 cacataactt tcttgaccat ctggaagttc aacttcacga gcatccatag ttgctcctaa
    27001 acggaatgtg ccattaggat tgctattcat tgcatctact aaatttttaa atgatgtata
    27061 taccccagtt tcactttgct gagtttttgg taaatagtat gtataatttt ctagtacatt
    27121 attattttca tgttgtatca gactatttgc acttgctact atcttataaa catctctatt
    27181 atctttagta tcattagtaa tgcttgtaac tggtagcatc acatctttaa agttctctga
    27241 tttaactttc ataaagtaat tttctgcatt acttggtaaa gaagcaagtg aagttacatg
    27301 tcgatactta ttaccatctt ttgaatatag ttctacagaa gatatatttc taagttctaa
    27361 tttcttaata acttcttttt catctttagc gtcatctttt ttctcatctt tatgacgata
    27421 aagttcatcg tatactggtg gaatttcatt acctgctata atactcttaa tccaagctaa
    27481 ttgtgtagga gataaaatca atccgcctga gcgattttgt gctccatttt gatgcacacc
    27541 aataacttca ccattagcat taaatattcc tccaccactc ataccaggat ttccaccttg
    27601 atattgaaca ccgtaggtgt tattcgcata ttcttgttcc atttctaccg tagcatcttt
    27661 taagtgcgta tatttcccag ctggatatcc atgaacattt agtttgtcat taagatttac
    27721 tttcgaataa tttttaacta attctacatg ttctctgcca gttgtttcag gtagcttaat
    27781 cactgctaaa tcatagataa atccttttgg ataatctttt ttattataaa aatgaatatt
    27841 gttagcagta aatgttcctt tttgtccatc aggagtcacc cactcatata cgtttttaga
    27901 tttatcacct ctaaattcgc cagtagtatt atcagtagaa ttattaatga aattatgtgc
    27961 tactgttaaa agtacatttg gtgcaataaa agtagctgat cctactccag taaccttcga
    28021 cgaatctgta ataaagttca tattaattaa tgcactagat tttttctgaa tactcatttc
    28081 ttctggtgta ttagtatttt cattatttgg tttagtatct tctgcactag gttgttcgat
    28141 tttaccagta tattctttca gtgcttctac tttctctggc tcgactatcg ctccggcttg
    28201 cacccctgtg tattctggta gtggtgctat ctgctctggt tcaacaatag cgccagcctg
    28261 cacccctgtg tattcttttg atggttctac tttttctggt tctactattg ctccggcttg
    28321 cactcctgtg tattccttcg gtgcttctac cttctctggt tcgactatcg ctccagcctg
    28381 cactcctgtg tattccttcg gtgcttctac tttctctggc tcgactatcg ctccggcttg
    28441 cacccctgtg tattctggta gtggtgctac ctgctctggt tcaacaatag ctccagcttg
    28501 tactcctgta tattctggta gcggttctac ctgctctgga tcacccttgt cagtcatgac
    28561 tgcctctggt aacgctggtt gaacttctgg tacgccttta tcacttacta cagcttctgg
    28621 caactctggt tggactgctg actcaccttt gtcggttaat acagctgctg gtagttcagg
    28681 ctgaattgcg ggttcaacaa tagctccaga ctgtacttcc ttatgttctg caccagtctc
    28741 agcttgttcc tttataactt gagctttttt agtacctttt tcgactattc ttgaaacagg
    28801 cgcagtcgtt gaagttgaaa taatttctcg tgaaacttct tcattgttta cagaaaatat
    28861 tctgacgatt tcaactttct tacctaatgc accttcttgt tttactctta cagttccttc
    28921 tgctaaatca ggattttctt gaatttcttc ttgaaaatct atttttgttt ctatagtttc
    28981 gtcacgatat aagagttccg gtttgttcaa ctgacctgat agcacttcat cctgtggatt
    29041 taatgtattt accccagtct tttcctttgg agaaatcttc tcctctttct tcgtttctag
    29101 attcttatgt tcggctaatt gttcttgaga atctgaagat tgtttctctt cttttcttgg
    29161 attgattaat tcagtagaga aaggtttttc aactacttga acttctgtcg gcttagttga
    29221 agaaacaggt gtttgttcct gaatagcttg tactgttgat ggatggtcta caaaatttgg
    29281 tgtaacatta taatccacct tttgttgttt tgtaggagtg gctgctgatt tttcttgatt
    29341 acttacttca aaatcagaag tcgtttttcc ctctttgata tatccaatat aagtgtaacc
    29401 tgaaatctct ttaggaagag gtaatttttc tccagaggtc aattcatagt ccgtattgta
    29461 atttagcaaa agatgatttt ctaaagcatg gactgaaact aagacaccat ttcccattcc
    29521 cgcaaccaat actaaatgta ataccgtttt attcttaacc tttttcttgg aaacagcaaa
    29581 aattaaaatt cccagagcag ctaagctagc accagcaact agggcttgcc tctcattctt
    29641 gcttccagta tttggtaatt ccgccagttg attttgagaa tttaacttat aaacaagata
    29701 ataagtttca tcatcattct ccacgtatgt cggaatatca tagacaagct gcttcttttc
    29761 ttctgatgat agctctgaat ctgccacata tttatagtga actcccgcag tttcttgagc
    29821 atccacagat gaactagcta atacagacat aaaaaataaa cttgaaatcg ttgcagatac
    29881 aagtcctact gataattttc taaatgaaaa acgctcttgt ttttcaccaa aatacttttc
    29941 cattattcct ccttgaaata aaatttatat atgttacaaa gacctttatt atattagtgt
    30001 attatctatt atctatagaa aaggcagtat accttaatta tactcttaat ttacaaaaaa
    30061 gtcttaaaat tgagatgcgc tttcatactt tgttttatat tatttggggg tacaataaca
    30121 cctaccatga aatttacacg gtaggtgtta ctcatatcac taatcgttct aaaaatggtt
    30181 tgaggcagtt gaggagaatt ccttctatcc agcttccttg tgctgatgag cgatggtctt
    30241 cctgcaggct tttttttaga aaatctcgga cttgttctgg tgcgatttca aattcaaagg
    30301 ctttcatttt atagaaaaag tcgatgagat gatcggacag gtattcagtt gaaaagggta
    30361 cttcaccact ttttcgatat tctaataaga gcctagaaaa tcgagctttt tcttcaggaa
    30421 gctcacgaaa ataggaattg aggagccaag tctgcttctg ttttctttca attggatcct
    30481 gactggcaat tcgttggtct ttttccagct ctttttggta ttgtttggcc ttgatagccc
    30541 gttctgctct atttttacca aaaagaattt tttcccactt gcgttcttct tgagtcaggg
    30601 tctctgtaaa gccaaagtaa tcttgataag cacgctctgc gggtcccatg gctagaacca
    30661 gattgtctgc atattgcttg gcgattttat ccctcttctt gcgttctttc tctgcctgga
    30721 tacggagttc ttgttcgtag tcaattttct ccttgcctag cttgacaagg tagagttggt
    30781 catccgattt cccaagtaaa aagggtttga tacacttttc aaggacttct tccatccgag
    30841 cctttttctt tggttccgcc ttggtccaac ttcctccctg aaagacttct aggaaaagct
    30901 ggtagtctct ctcaggcgca aattgattgc cacgattggg tttgaaaaca cctttttccc
    30961 agagccattt tagaagtcgc tcgtcaaagt cacttttatt gaccttgatt ttttcctttt
    31021 tctgagcttt tctggttaga ttttcaacct ttctgagcag tttttcttcc tcttccaatt
    31081 gctggtcaag ggacaatcga tgaaaatgac gaacacagtc gctaccaatt ggaaagaggc
    31141 gttggcctgt gacaccgtta aagagttcat aagcgtattt gatggcattt ccacagacac
    31201 aattgctacg gccgataccg ttaaaaatca aggaaacttc attccattcc ttggtagctt
    31261 gttcccaagt atccgctttc gaagcctgta aaactgcatc gtgcagggat tttctaactg
    31321 gaagtgtcat gaggtctcct ttctaatact caataaaaat caaagagcaa actagaaagc
    31381 tagccgcaat cagctcaaaa cactgttttg aggttgtaga tagaactgac gaagtcagct
    31441 caaaacactg ttttgaggtt gtggatagaa ctgacgaagt cagtaaccat atatacagca
    31501 aggcgaagct gacgtggttt gaagagattt tcaaagagta taagttatac ttttacaact
    31561 tgaacctcgt ctttaccgag taaaatcaag tatttttcaa tattttcaat cgaataggct
    31621 cgtgataaag cctcttcgta tagagctaac tgaccacgat agcggtctac gagttgactt
    31681 ggttcatcat agcggtctgt cttgtagtcg aacagaacaa ttttgttttc gtaaagcaga
    31741 tagccatcaa ggataccacg gacaacaaag tcttcctgac tcttttggtc tcgtttgagc
    31801 atggagaaag gttgctcgcg atagagatgg tcggtattag caagaatttc ctgaccgagt
    31861 actgtgtcaa agaaagcaag aattttatca agattgatct tgtctctgac agcttggcta
    31921 gtttgaactt gtttgagtgt ttctgttagg ctagcaaggg ttagttgctg gctgaggtca
    31981 attctctgca tgagttcgtg agtagcacta ccaatctcag ctccagttac cttttctttg
    32041 gttgaaaaat ctggcaaatc gaagctgatt ttcttgccta ctgactgacc ttgaccagca
    32101 atctcgacac cttccatatc cataactggt tcgtagaatt tcttgatttg acttggggtt
    32161 tgaacactag gaagttcaat agctgcgcgg tgaagagtat tataaacttc cacctccttc
    32221 agcatttcca gagcttcttt gatggtatct gactgacgat tgtctgcttg ggagctatct
    32281 tggagaggac tcttggtttc caactctccg atagcttctc tggtcaactg atcttcgcca
    32341 ataaaacgat aactaaagtt gagcttgtcc ttagtaaaca ctttactgat agcccaaagc
    32401 caatcttgga aattccgtgc ttgcagtcta gtattgctat ttagtttccc atttttggct
    32461 gctgggtatt gcttgacttc cagcttttca cgagaaccct tgccgacaag atagagcttt
    32521 ttctcagccc gcgtcatagc aacatacagc aaacgcatct gctcagaata gcttgctagc
    32581 tgtaattcct cttcgttctg cctataggtc agactaggaa tggagagttt gatggtttta
    32641 ggatagtggt cttctactgc ccctgtctcc atcttggcaa tatatttgac accaagacca
    32701 ttctgacgac tgagaatgac ttctgacata gagtcttgct tgttgaaatc ttgatccata
    32761 ttgaggataa agacgtaagg aaactccagc cctttactct tgtggatggt catgagctct
    32821 actgcatctt ttggcggtgc gacggccacg cttgccaaat cgtgctgggc ttctaagact
    32881 tggtcaatca tacgaataaa acgcgacaaa cctttgaaat tgctcttttc aaattgatca
    32941 gcacgcagtg ctagggcata gagattggcc tgcctagcag gaccattcgg caaagcccca
    33001 acatagtcat aataaaaacg gtcgttgtaa atcttccaaa tcaagtcata gagagagtgg
    33061 gttttggcat acaagcgcca agaagctagg atatccatga attgctttag tttttcagct
    33121 agagctgtgt gaatcaaacc tttttgacta cttgccattt tttgtgcatt gaccagtttc
    33181 tcatagagat tttcgtggac tttatcctct gctttctgaa gggacaaacg tgctagctca
    33241 tcctcatcaa aaccaaacat tggagacttc ataagggcaa ccaaagcgta gtcttgcagg
    33301 ggattgtgaa tgacacgaag agtgtctagc atgacttgca cttctaggga ttggagataa
    33361 ttgttttgct ctccgtcagt tttgacagga attccgtact cagacagggc gaggagaatc
    33421 tggtcattac gactgcggct ggaggtcaga agggcaattt ccttaaaggc aacacctttt
    33481 tcttgatgaa gtttcagaat ctccttgata actaagcgca tttcgcctgt tagtttcgtt
    33541 tctgtttgac tctcttcttc ctcacctgta tcgtccttgt cgtagaggag aaattctgcc
    33601 ttgttgtctg gattgggagt cagtttggta ttggcaaaaa caagctggtg catgttatca
    33661 tagttgattt cgccgacctc ttggtccatg agacgttcaa agacatcatt ggttgctgac
    33721 agcacttctg aactactacg gaaattttcc ttgaggagaa tgagcttgcc ttcttgagga
    33781 ttttgcgcat agcgttggaa tttctcattg aaaatctgcg ggtctgcctg acggaaacga
    33841 tagatggatt gcttgatatc tcccaccata aagcgattgt ggccattaga caacaattcc
    33901 agcatccgtt cttgaatatg gttggtatcc tgatactcat cgaccatgac ttcatggaag
    33961 cgctcctgat aagactcacg aacttgtggg aaattttcta aaatctcaat ggtgtaatgg
    34021 ctgatatcag cgaattcaaa ggcattttcc tgtcgttttc tctgacgata agcctctaca
    34081 aaatcgctca tgaaagattg gaaggtttta gctagtttcc aagtgtctcc atgataacgt
    34141 tcttgatagt cgagaatggt tatctggtct gataattgtc ctagtttagt aaactgggtc
    34201 tttctctctt cgttgtaggc atcagccagg ggcttcaaat cagccttacg gctggcatta
    34261 gtcagagctc gaccgttttt ctccttagag atggcgacaa cacgcgcaag cactgcctga
    34321 taagcctgac tatcgaactc ctgatttagg gagccaattt catccagaat taactgaaca
    34381 ttttctaaat aggcagcctt tgcaaactcc ttggcatcgt tatccagatg gtaacggaaa
    34441 aagctttcca aatcccagag ggcttgtttg atttgctcag tcagtttttc tttttcactg
    34501 gtaaaatcag ctttctcaaa gcctttgagg aaagattcac tcagccactt ttgaggatta
    34561 ctggtggatt ggaggaagtc atagatttta tagacttgct ggcgcagacc ccgttcgtcc
    34621 ttgccacgcc cagcaaagtt tttcagcaaa tgactaaagc tctctttctg tttaccttgg
    34681 taatgcgctt caaagacctc atgaaagact tcgttttcga gaagaagttg ctcgctttgg
    34741 ttttgtaaaa tacggaaatt aggtgcaata tcaagcagat aaccatgttt gccaaggaat
    34801 ttttgtgtga aagagtccat ggttccgatg gcagcgttgg gtaggtctgc caactggcaa
    34861 cccaagtgtt gtttgagatc gacatcatct gtttcttgga ttttcttgct gatttttttc
    34921 tctaaacgtt ctttaagttc agttgcagcc ttgacggtaa aggttgagat aaagagttga
    34981 gaaatttcga caccacgcgc caattggtcc agaatgcgct ctaccatgac aaaggtcttt
    35041 ccagaaccag ccgatgctga gaccaggata ttctgaccag aagtgtagat agcttcgatt
    35101 tgttcggcag ttttcttctg ttccttgctc gaatttgctt ctgcttcttg cagtttttga
    35161 atctcctcct cacttaaaaa gggaataagc ttcatcgatt taactcctct cttatttttt
    35221 caaaccaagc ttgcttgagt ttttctccga ccagacgctt gccatcagct aggtccaact
    35281 tttctaggaa acgggcttgg cccagatggt aattggcttc aaagcctgta atagcctgat
    35341 gttgctggac gtatggggca atgcttctgc cattttcagt ataaggattg atggcgaacc
    35401 ggcctgctaa aatcttctca gcagctttct tgtaaagata ggcattgtag tccagtagga
    35461 gctgaaattc ctcatctgtc agttgattag ccttgttttt gttataaaat tcgcctaaat
    35521 aactgctttc tttttccaag aagagccctt ggtatttcat agatttgctg gcttctacca
    35581 ctgctcctgc cagacttttt accgccatca gagattggac aggttcagcc atttccaagt
    35641 acatggcgcc gaaaaagttc tgctcccctt ctctttttag ggcagcaaga taggttggta
    35701 actgagaatt gagcccatta aagaaatgag gaaactggaa ctgagtcaga ctggatttgt
    35761 agtctactac tcctatcgct ccattagctt tcaaacggtc aatccggtcc accttgcctc
    35821 gtacaaagac actgcgtcca ttgtctaatt gaataaaggc ttggtctttt ccaccaaaat
    35881 ttgcttcttc tttgatggtt tcgatggctg gattgtgtcg gagaatatgt ccagtcgtcc
    35941 gtgcaacatc aagcaaaact tccttggtaa actgggcttc caaactttct tgataaatag
    36001 cttcaaattc gcgttcttga ctggtttctt gaatagcttg ttctagacgt tggtcaaagg
    36061 aatcttcatt aggcaactgt aaggcgcgtt caaagatacg atgcaagaaa ttcccgtgac
    36121 tacgggcatc aggacgcaaa cgtaattcct cctgcaagcc taaaacgtag cgtaggaaat
    36181 aactgtattc attgcgataa aactctgtca aacccgacgt agacaggtaa aactcctgtt
    36241 tggcaggata gagagcttgc aaggtgtcct tggctaaggt cttgctgctt ggactggttg
    36301 ggatagctgg attttccaga ccttgcagat ctagtttttt acctatgaca cgcgacagaa
    36361 ccttgacaaa agtcaaatct tgctcagtat cgctcatctc accctgctgg tgataggcaa
    36421 ccagactaga caaaagactg tgataggacc ccatatcctc cttagacagt cctttgtgat
    36481 tcattctctt ctctctccgc ctaaatccaa aatggatcaa ctcttgaaga taggcagatt
    36541 ccttactttc actttcgtta aaaaggcttg gagccgacaa gaacaactgc ttacgagcag
    36601 aattgaccaa ggaaagcata gtgtagcgat ttttcttgag attttcactg ctggcaatca
    36661 gtaattgaac gccttcttcg gtcgtttggt ttaggttttt cctttcttca tctgtcagaa
    36721 gactggtgtt ttgagaaatt tttggtaaat tgtcctgagt tagtccaata gcatagacaa
    36781 agtcagcagt caatggtgca atcaaatcgt aactctgcac cagaacagtg tccactgttg
    36841 ctggaatggt acggtattgg gacaaactca ttccagaatg gagcaaggct aggaagtctt
    36901 ccagactaac ctgtgaacca gcaaaaacag tcgcaaattg ttctaaaaca tggcaaaaag
    36961 ccttccaaac ttcggcttgt ctttcctgtt ctacagcttc caaagtggtt gtcaaatctt
    37021 gtaactgctt ggtcacagct ccttctttta gaaagacact ccatttttgt aggaggtttt
    37081 cagccttttg ttttcggctg gcaaagaggg tttcaagagg tgctaaaatt ctcaggcgga
    37141 ggacattcaa acgctcaaga ttaaattttc catggtggga tttggtgaag gtttgctgaa
    37201 aggctggcaa gccattaata ccaagatagc ggatatattg ttcaaaagca tcaatatcag
    37261 actgactgag gtcaatatac aagtcagttc taagaagatt aatcaaatcc tcctgacgaa
    37321 aacggtaacg ttttaaagct aaaatagact cgacaaactg agtcaaggga tgatgagcca
    37381 tggcttcgct tctaccaaga taaaaaggaa tctgatactg gtcaaaaatg gttttgagag
    37441 ataactggta agaagctaca tcccccaaga gaatacgaaa atgcttgtag ctcaggtctg
    37501 agttctcatg taatttctga cgaatgctac gggctactag ctccaactcc tccttttgcg
    37561 tcaaacaaga ccagatttgt aaattttcac ggtctttctc atcgacatcc aaagcgagtt
    37621 ctgaaaagtc ataagaagac tccaacaaac gagaggcctt gtcaaaacta tccatcttct
    37681 catgagtttg agaacagtcc tgagcgggcg tttggtattt agaagccaga tgatggagaa
    37741 attttacgct ggcttggtag agattgccct cgctaaaagg actggtatag gctttcttac
    37801 tagcataagc cccgataaca atctcagcac ctttgccgtg aagtaagtcc acaacccgct
    37861 cttcctcagc agaaaaacga gtaaagccgt caatgaccaa ggcgatttga ttaaaatcac
    37921 tacttacctt gtcattctca atagcctcaa tcaaatggga caactgactt ccctgggcta
    37981 actgcccttg attaagatag gctgttactt tctcaaaaat caagagtaaa tccgccctct
    38041 tatcctcatc tgttaaattc tccaagtcca aaaaattcat ctgagatttg gtcatctcat
    38101 ggtaaagctc aattaactgc tggatcaatt gaggatcctg cttaatagcg ccataaacac
    38161 gcaagtcctt gggatcgagt tcggcaaggc atttgtaaaa ggccaaccca agaccgatat
    38221 catcaagagt agttttagct ggtaaatcat tcaagaccag ataacgagcc atttgagcaa
    38281 agcgcgtgac ggtaatcgaa aaagaagcct gctgggacaa gcattccagc acggcgcgtt
    38341 ccttttcaaa agaaagagag ttgggggcaa tgtagaagac ccgcttgcca gctgcaacta
    38401 gctcttctgc ctctcttgtt agaatttctg tcaaagaagt tcgaatatca gtataaagta
    38461 atttcatctc agcctcgttg gaatttttca tcaccctata ttataccatg attagcctcg
    38521 taaatctgtt aaaatattta ggccatcctt tcttttcttc atcatctgct aaatcttaaa
    38581 tacttagctt tacttgtatt agatagaata agtctggcta ctgaaaatca cataataaaa
    38641 aagcctcggt aacaaggctt tgagttttat gattgtttct taggtacgga atacacttca
    38701 atgtgttgtc ccagtatctt aatgtcgacg ggtagattgt ctgatttatc gccatcaaca
    38761 tcggactcta attcgatatc agaagaagtt ttaatattac gtgcctttat atattcaata
    38821 ttcttgatag aatgattgaa ctatagtaaa ttgaaactat aatagtacac cgtggatgct
    38881 aaaatatttc tagaaattaa tttgatttcc ctaatcaagc tgttcgtatc ttatttcaat
    38941 ctactatagt aaaatgaacc aaaaatag
//
LOCUS       DBEJHE010000020        35741 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC4 isolate 671759
            SAMN38261586-rid24793303.denovo.20, whole genome shotgun sequence.
ACCESSION   DBEJHE010000020 DBEJHE010000000
VERSION     DBEJHE010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261586
            Sequence Read Archive: SRR26833752
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 35741)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35741)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576136.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576136.1
            Genome Coverage       :: 109x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 19:48:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,067
            CDSs (total)                      :: 2,029
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 131
            CDSs (without protein)            :: 131
            Pseudo Genes (ambiguous residues) :: 0 of 131
            Pseudo Genes (frameshifted)       :: 64 of 131
            Pseudo Genes (incomplete)         :: 59 of 131
            Pseudo Genes (internal stop)      :: 46 of 131
            Pseudo Genes (multiple problems)  :: 32 of 131
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35741
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261586-rid24793303.denovo.20"
                     /strain="GPSC4"
                     /isolate="671759"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            236..1681
                     /locus_tag="ACL3EZ_001327"
     CDS             236..1681
                     /locus_tag="ACL3EZ_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000091082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0070726 - cell wall assembly [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HGR0392890.1"
                     /translation="MSRRFKKSRSQKVKRSVNIVLLTIYLLLVCFLLFLIFKYNILAF
                     RYLNLVVTALVLLVALVGLLLIIYKKAEKFTIFLLVFSILVSSVSLFAVQQFVGLTNR
                     LNATSNYSEYSISVAVLADSDIENVTQLTSVTAPTGTDNENIQKLLADIKSSQNTDLT
                     VDQSSSYLAAYKSLIAGETKAIVLNSVFENIIESEYPDYASKIKKIYTKGFTKKVEAP
                     KTSKNQSFNIYVSGIDTYGPISSVSRSDVNILMTVNRDTKKILLTTTPRDAYVPIADG
                     GNNQKDKLTHAGIYGVDSSIHTLENLYGVDINYYVRLNFTSFLKLIDLLGGVDVYNDQ
                     DFTSLHGKFHFPVGNVHLDSEQALGFVRERYSLADGDHDRGRNQQKVIAAILQKLTSS
                     EALKNYSRIIDSLQDSIQTNMPLETMINLVNAQLESGGTYKVNSQDLKGMGRTDLPSY
                     AMPDSNLYMMEINDSSLASVKTAIQDVLEGR"
     gene            1683..2414
                     /gene="cps4B"
                     /locus_tag="ACL3EZ_001328"
     CDS             1683..2414
                     /gene="cps4B"
                     /locus_tag="ACL3EZ_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Cps4B"
                     /protein_id="HGR0392891.1"
                     /translation="MIDIHSHIVFDVDDGPKSREESKALLAESYRQGVRTIVSTSHRR
                     KGMFETPEEKIAENFLQVREIAKEVASDLVIAYGAEIYYTSDVLDKLEKNRIPTLNNS
                     RYALIEFSMNTPYRDIHSALSKILMLGITPVIAHIERYDALENNEKRVRELINMGCYT
                     QVNSSHVLKSKLFGERYKFMKKRAQYFLERDLVHIIASDMHNVDSRPPHMAEAYDLVS
                     QKYGEANAQELFIDNPRKIVMDQLI"
     gene            2423..3115
                     /locus_tag="ACL3EZ_001329"
     CDS             2423..3115
                     /locus_tag="ACL3EZ_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000664160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein"
                     /protein_id="HGR0392892.1"
                     /translation="MKEQNTIEIDVFQLLKTLWKHKLIILLVALVTGAGAFAYSTFIV
                     KPEYTSTTRIYVVNRNQGDKPGLTNQDLQAGTYLVKDYREIILSQDVLEKVATNLKLD
                     IPAKTLTSKVQVTVPADTRIVSISVKDKQPEEASRIANSLREVAAEKIIAVTRVSDVT
                     TLEEARPAMTPSSPNVRRNTLVGFLGGAAVTVITVLLIELFDTRVKRPEDVEDVLQMP
                     LLGVVPDFDKMK"
     gene            3125..3814
                     /locus_tag="ACL3EZ_001330"
     CDS             3125..3814
                     /locus_tag="ACL3EZ_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein kinase"
                     /protein_id="HGR0392893.1"
                     /translation="MPTLEISQAKLELVKKAEEYYNALCTNLQLSGDDLKVFSITSVK
                     AGEGKTTTSTNIAWAFARAGYKTLLIDADMRNSVMSGVFKSRERITGLTEFLSGTTDL
                     SQGLCDTNIENLFVIQAGSVSPNPTALLQSKNFSTMLETLRKYFDYIVVDTAPVGVVI
                     DAAIIMQKCDASILVTKAGETKRRDLQKAKEQLEQTGKSCLGVVLNKLDTSVEKYGSY
                     GSYGNYRKQKK"
     gene            3829..5190
                     /locus_tag="ACL3EZ_001331"
     CDS             3829..5190
                     /locus_tag="ACL3EZ_001331"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HGR0392894.1"
                     /translation="MSEKLAKPSVAIVQSFLVILLTYLLSAVRETEIVSTTAIVLYIL
                     HYFVFYISDYGRNFFKRGYLIELVQTLKYILFFALAISISNFFLEDRFSISRRGMIYF
                     LLLHVFLVYVLNPFIKWYWKRAYPNFKGSKKILLLTATSRVEKVLDRLIESDDVVGEL
                     VAVSVLDKPDFQHDDLKVVAEGEIVNFATHEVVDEVFINLPSEKYNIGELVSQFETMG
                     IDVTVNLNAFDWARNKQICEMAGLNVVTFSTTFYKTSHVIAKRVIDIVGSLVGLILCG
                     LVSIVLVPLIRKDGGSAFFAQTRIGKNGRHFTFYKFRSMCVDAEEKKRELMEQNTMQG
                     GMFKVDDDPRITKIGHFIRKTSLDELPQFYNVLKGDMSLVGTRPPTVDEYEHYTPEQK
                     RRLSFKPGITGLWQVSGRSEIKNFDEVVKLDVAYIDGWTIWKDIEILLKTVKVVLMKD
                     GAK"
     gene            5196..5939
                     /locus_tag="ACL3EZ_001332"
     CDS             5196..5939
                     /locus_tag="ACL3EZ_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001005725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WecB/TagA/CpsF family glycosyltransferase"
                     /protein_id="HGR0392895.1"
                     /translation="MNERIQILGITIDPLTMKETVDAVEQYVLKKHPLHLMGVNADKI
                     NQCYEDEKIKKIVNESGIINADGASVVLASKFLGTPVPERVAGIDLMKHLLELSNEKG
                     YSVYFFGAKEDVLQDMLKIFEERYPALNVVGYRNGYFSPEDEKHIQEDIKEKKPDFVF
                     VGITSPKKEYIIQSFMDNGINAVFMGVGGSFDVLSGHIKRAPLWMQNAHLEWLFRVAN
                     EPKRLFKRYFVGNVSFIRKVLRAKRGYKL"
     gene            5936..6760
                     /locus_tag="ACL3EZ_001333"
     CDS             5936..6760
                     /locus_tag="ACL3EZ_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001076787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LicD family protein"
                     /protein_id="HGR0392896.1"
                     /translation="MNQTEIVKLIQKVELDAIKEFQKICKENNIDFFLRGGSVLGAVK
                     YDGFIPWDDDMDIAVPREGYDKLPGIFKDRIIAGKYQVLAYQYCDTLHCYFPRLFLLE
                     DERKRLGLPRNTNLGLHLIDIIPLDGAPNHSFLRKLYFGKVYWYRFLASLGTTYVGDH
                     VDMHSAKQKLIIGFFKKLGFAKLFPQNYVYRRLDNLYKKYDWKKQKYAGTINASLFAK
                     EVMPVEIWGEGVEKPFEDAFFKVPTEYDRYLKRLYGENYLHEEPSDDEKKSHLGGQ"
     gene            6762..7640
                     /locus_tag="ACL3EZ_001334"
     CDS             6762..7640
                     /locus_tag="ACL3EZ_001334"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HGR0392897.1"
                     /translation="MFCYIILHYKVLEETISCVKSIKEGNSNTKQIVIIDNFSNNGTG
                     EKLQELYESDSEIDVLINHENAGFARGNNVAYQFAKEKYKPDFMVIMNNDIEIETEEF
                     EKIVTDIYRKEKFHLLGPDIFSTTYQLHQNPKRLTHYTYEEVKALNEKFKKGSQVSLA
                     LKIKCWLKSSKVLRTAIYQNRRKKKSVDYRKQVENPILHGSFIVYSRDFIEKEEYAFN
                     PNTFFYYETEILDYEAELKGYKRIYTPKIKVLHHQNVATNQVYTNLVEKTLFSNKCNF
                     ESTSYFLKLMKENEGV"
     gene            7641..8975
                     /locus_tag="ACL3EZ_001335"
     CDS             7641..8975
                     /locus_tag="ACL3EZ_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008755 - O antigen polymerase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polymerase"
                     /protein_id="HGR0392898.1"
                     /translation="MTYLFLLCLTLFLLTFFYFFAFNQDLIAPPVVMSVMFLISSVFA
                     LINVQNWNIEYSGLAYLLIISGIIVFSMPLLALNSPILNTKIKVTDRLIDIQFWKIAL
                     TIIVDLIILYLYRREIHNLALSHGYTGSNFQWFFRNATSYEGELTVRTSIRVLIRIID
                     VSAYIFGYTFINNFFIYSHKRSKDLLLLVPFLIFISKTLLSGGRLDIIKILIAYVVMA
                     YIQQKRKVGWDKVISHKYMRLGFVGLIAGIPTFYYSLFLSGRSTTRTVFESISTYLGG
                     SIQHFNQYIQNPIGVAEVFGDESFVAIMNILGNLGFVNYNSTVHLEFRQLGITMGNVY
                     TFFRRPWHDFGLVGMYIFSFVVGVFFAIFYLKLRKSRAGFKLDIHTIIYSYFFYWIFL
                     SSIEQYSFTTISLFTLVFIVLVYLMAFFYWNLDFHRGKLVIKLSDTSIKSEN"
     gene            9003..10427
                     /locus_tag="ACL3EZ_001336"
     CDS             9003..10427
                     /locus_tag="ACL3EZ_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001085099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0392899.1"
                     /translation="MNSKIKNILTNFSYVISSNLLTVLTSSLVVLIFPKLMGVTEYSY
                     WQLYIFYLTYIGFFHLGWIDGIYLKYGGLEYNNLDRKQFYSQMILFSSFLMIISLLLF
                     GLNVLAVTDSNARYIYNMTIISMIITNLRTLYVYVLQMTNRLKDSSIILLSDRVLYVL
                     LLFLFIVFGWHEYKVMILADILGRSFSLILSFWICKDIVFQPLSKFIFNIKESFDNIR
                     VGINLMLSNIASSLIIGIVRLGIQWNWNIETFGKVSLTLSVSNLLMTFINAIGLVVFP
                     LLRRTKAENLPKIYSNLRNVLMLIMFAILLIYYPLKIVLDLWLPAYQDALIFMTLIFP
                     MSVYEGKMALVINTYLKALRMERDILRVNALVMLISMGVTLVTTYLLNSLELTVVSIV
                     VLLALRSIIAELILSKKLDVSVKKDIVLEFLLTLVFISSSWYLPIGLAVIVYTIAYGL
                     YLYLKHEDIKTYLAYFKASKKTSN"
     gene            10492..11580
                     /gene="wecB"
                     /locus_tag="ACL3EZ_001337"
     CDS             10492..11580
                     /gene="wecB"
                     /locus_tag="ACL3EZ_001337"
                     /EC_number="5.1.3.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000723326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008761 - UDP-N-acetylglucosamine
                     2-epimerase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="non-hydrolyzing UDP-N-acetylglucosamine
                     2-epimerase"
                     /protein_id="HGR0392900.1"
                     /translation="MKKIMLVFGTRPEAIKMCPLVNELKKHEDMETIVCVTGQHKEMV
                     SPVLDLFGVVPDYDLEIMKANQTLFSITTSILEKIKPVLEKEQPDIVLVHGDTTTTYA
                     AALAAFYLGIKVGHVEAGLRTYNLQSPFPEEFNRQSTSIIATYHFAPTELAKENLLKE
                     GRENVYVTGNTVIDALTTTVQEDYTHTHLDLNANNRLILLTAHRRENLGEPMRHMFRA
                     VKRVLNEYEDVKVIYPIHKNPLVRETAAEIFGDTERIQIIEPLDVLDFHNFMNQSYMI
                     LTDSGGVQEEAPSLGKPVLVMRDTTERPEGVAAGTLKLVGTDEETIYQNFKLLLDDSG
                     EYKKMSQASNPYGNGDASQQIVQILRGI"
     gene            11743..12612
                     /gene="rfbA"
                     /locus_tag="ACL3EZ_001338"
     CDS             11743..12612
                     /gene="rfbA"
                     /locus_tag="ACL3EZ_001338"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002276675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008879 - glucose-1-phosphate
                     thymidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0045226 - extracellular polysaccharide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HGR0392901.1"
                     /translation="MKGIILAGGSGTRLYPLTRAASKQLMPVYDKPMIYYPLSTLMLA
                     GIKDILIISTPQDLPRFKDLLLDGSEFGIKLSYAEQPSPDGLAQAFLIGEEFIGDDSV
                     ALILGDNIYHGPGLSTMLQKAAKKEKGATVFGYQVKDPERFGVVEFDTDMNAISIEEK
                     PEYPRSNYAVTGLYFYDNDVVEIAKQIKPSARGELEITDVNKAYLNRGDLSVELMGRG
                     FAWLDTGTHESLLEASQYIETVQRMQNVQVANLEEISYRMGYISREDVLELAQPLKKN
                     EYGQYLLRLIGEA"
     gene            12613..13206
                     /locus_tag="ACL3EZ_001339"
     CDS             12613..13206
                     /locus_tag="ACL3EZ_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase family
                     protein"
                     /protein_id="HGR0392902.1"
                     /translation="MSDNFFGKTLVVRKIDAIPGLLEFDIPVHGDNRGWFKENFQKEK
                     MLPLGFPESFFAAGKLQNNVSFSRKNVLRGLHAEPWDKYISVADDGKVLGSWVDLREG
                     ETFGNVYQTEIDASKGIFVPRGVANGFQVLSDTVSYSYLVNDYWALELKPKYAFVNYA
                     DPALGIEWENLAEAEVSEADKHHPLLRDVKPLTKDEL"
     gene            13218..14264
                     /gene="rfbB"
                     /locus_tag="ACL3EZ_001340"
     CDS             13218..14264
                     /gene="rfbB"
                     /locus_tag="ACL3EZ_001340"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008460 - dTDP-glucose 4,6-dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009225 - nucleotide-sugar metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HGR0392903.1"
                     /translation="MTEYKKIIVTGGAGFIGSNFVHYVYNNFPDVHVTVLDKLTYAGN
                     RANIEEILGDRVELVVGDIADAALVDKLAAEADAIVHYAAESHNDNSLNDPSPFIHTN
                     FIGTYTLLEAARKYDIRFHHVSTDEVYGDLPLREDLPGHGEGLGEKFTAETKYNPSSP
                     YSSTKAASDLIVKAWVRSFGVKATISNCSNNYGPYQHIEKFIPRQITNILSGIKPKLY
                     GEGKNVRDWIHTNDHSSGVWTILTKGQIGETYLIGADGEKNNKEVLELILKEMGQPAD
                     AYDHVTDRAGHDLRYAIDASKLRDELGWKPEFTNFEAGLKETIKWYTDNQDWWKSEKE
                     AVEANYAKTQQVIK"
     gene            complement(14326..15180)
                     /gene="rfbD"
                     /locus_tag="ACL3EZ_001341"
     CDS             complement(14326..15180)
                     /gene="rfbD"
                     /locus_tag="ACL3EZ_001341"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008831 - dTDP-4-dehydrorhamnose reductase
                     activity [Evidence IEA];
                     GO_process: GO:0009243 - O antigen biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HGR0392904.1"
                     /translation="MILITGANGQLGTELRYLLDERNVDYVAVDVTEMDITNSEMVEK
                     VFAEVKPTLVYHCAAYTAVDAAEDEGKELDFAINVTGTENVAKASEKYGAILVYISTD
                     YVFDGKKPVGQEWEVDDIPDPQTEYGRTKRMGEELVENLTSQHYIIRTAWVFGNYGKN
                     FVFTMQSLAKTHKTLTVVNDQYGRPTWTRTLAEFMTYVTENQKEYGYYHLSNDAAEDT
                     TWYDFASEILKDSDVEVVPVDSSKFPAKAKRPLNSTMSLAKAKATGFVIPTWQDALKE
                     FYKQEVRK"
     gene            15426..17408
                     /locus_tag="ACL3EZ_001342"
     CDS             15426..17408
                     /locus_tag="ACL3EZ_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HGR0392905.1"
                     /translation="MKSSKLFALAGVTLLAATTLAACSGSGSSTKAEKTFSYIYETDP
                     DNLNYLTTAKAATANITSNVVDGLLENDRYGNFVPSMAEDWSVSKDGLTYTYTIRKDA
                     KWYTSEGEEYAAVKAQDFVTGLKYAADKKSDALYLVQESIKGLDAYVKGEIKDFSQVG
                     IKVLDDQTVQYTLNKPESFWNSKTTMGVLAPVNEEFLNSKGDDFAKATDPSSLLYNGP
                     YLLKSIVTKSSVEFAKNPNYWDKDNVHVDKVKLSFWDGQDTSKPAENFKDGSLTAARL
                     YPTSASFAELEKSMKDNIVYTQQDSITYLVGTNIDRQSYKYTSKTSDEQKASTKKALL
                     NKDFRQAIAFGFDRTAYASQLNGQTGASKILRNIFVPPTFVQADGKNFGDMVKEKLVT
                     YGDEWKDVNLADSQDGLYNPEKAKAEFAKAKSALQAEGVTFPIHLDMPVDQTATTKVQ
                     RVQSMKQSLEATLGADNVIIDIQQLQKDEVNNITYFAENAAGEDWDLSDNVGWGPDFA
                     DPSTYLDIIKPSVGESTKTYLGFDSGEDNVAAKKIGLYDYEKLVTEAGDEATDVAKRY
                     DKYAAAQAWLTDSALIIPTTSRTGRPILSKMVPFTIPFALSGNKGTSEPVLYKYLELQ
                     DKAVTVDEYQKAQEKWMKEKEESNKKAQEDLAKHVK"
     gene            17708..23011
                     /locus_tag="ACL3EZ_001343"
     CDS             17708..23011
                     /locus_tag="ACL3EZ_001343"
                     /EC_number="3.2.1.97"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001032503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033926 -
                     endo-alpha-N-acetylgalactosaminidase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SpGH101 family
                     endo-alpha-N-acetylgalactosaminidase"
                     /protein_id="HGR0392906.1"
                     /translation="MNKGLFEKRCKYSIRKFSLGVASVMIGAAFFGTSPVLADSVQSG
                     STANLPADLATALATAKENDGRDFEAPKVGEDQGSPEVTDGPKTEEELLALEKEKPAE
                     EKPKEDKPAAAKTETPKTVTPEWQTVEKKEQQGTVTIREEKGVRYNQLSSTAQNDNAG
                     KPALFEKKGLTVDANGNATVDLTFKEDSEKGKSRFGVFLKFKDTKNNVFVGYDKDGWF
                     WEYKSPTTSTWYRGSRVAAPETGSTNRLSITLKSDGQLNASNNDVNLFDTVTLPAAVN
                     DHLKNEKKILLKAGSYDDERTVVSVKTDNQEGVKTEDTPAEKETGPEVDDSKVTYDTI
                     QSKVLKAVIDQAFPRVKEYSLNGHTLPGQVQQFNQVFINNHRITPEVTYKKINETTAE
                     YLMKLRDDAHLINAEMTVRLQVVDNQLHFDVTKIVNHNQVTPGQKIDDERKLLSSISF
                     LGNALVSVSSDQTGSKFDGATMSNNTHVSGDDHIDVTNPMKDLAKGYMYGFVSTDKLA
                     AGVWSNSQNSYGGGSNDWTRLTAYKETVGNANYVGIHSSEWQWEKAYKGIVFPEYTKE
                     LPSAKVVITEDANADKKVDWQDGAIAYRSIMNNPQGWEKVKDITAYRIAMNFGSQAQN
                     PFLMTLDGIKKINLHTDGLGQGVLLKGYGSEGHDSGHLNYADIGKRIGGVEDFKTLIE
                     KAKKYGAHLGIHVNASETYPESKYFNEKILRKNPDGSYNYGWNWLDQGINIDAAYDLA
                     HGRLARWEDLKKKLGDGLDFIYVDVWGNGQSGDNGAWATHVLAKEINKQGWRFAIEWG
                     HGGEYDSTFHHWAADLTYGGYTNKGINSAITRFIRNHQKDAWVGDYRSYGGAANYPLL
                     GGYSMKDFEGWQGRSDYNGYVTNLFAHDVMTKYFQHFTVSKWENGTPVTMTDNGSTYK
                     WTPEMRVELVDTDNNKVVVTRKSNDVNSPQYRERTVTLNGRVIQDGSAYLTPWNWDAN
                     GKKLSTDKEKMYYFNTQAGATTWTLPSDWAKSKIYLYKLTDQGKTEEQELTVKDGKIT
                     LDLLANQPYVLYRSKQTNPEMSWSEGMHIYDQGFNSGTLKHWTISGDASKAEIVKSQG
                     ANDMLRIQGNKEKVSLTQKLTGLKPNTKYAVYVGVDNRSNAKASITVNTGEKEVTTYT
                     NKSLALNYVKAYAHNTRRDNATVDDTSYFQNMYAFFTTGSDVSNVTLTLSREAGEQAT
                     YFDEIRTFENNSSMYGDKHDTGKGTFKQDFENVAQGIFPFVVGGVEAVEDNRTHLSEK
                     HDPYTQRGWNGKKVDDVIEGNWSLKTNGLVSRRNLVYQTIPQNFRFEAGKTYRVTFEY
                     EAGSDNTYAFVVGKGEFQSGRRGTQASNLEMHELPNTWTDSKKAKKVTFLVTGAETGD
                     TWVGIYSTGNASNTRSDSGGNANFRGYNDFMMDNLQIEEITLTGKMLTENALKNYLPT
                     VAMTNYTKESMDALKEAVFNLSQADDDISVEEARAEIAKIEALKNALVQKKTALVAED
                     FASLTAPAQAQEGLANAFDGNLSSLWHTSWGGGDVGKPATMVLKEATEITGLRYVPRG
                     SGSNGNLRDVKLVVTDESGKEHTFTATDWPDNNKPKDIDFGKTIKAKKIVLTGTKTYG
                     DGGDKYQSAAELIFTRPQVAETPLDLSGYEAALAKAQKLTDKDNQEEVASVQASMKYA
                     TDNHLLTERMVEYFADYLNQLKDSATKPDAPTVEKPEFKLSSLVSNQGKTPDYKQEID
                     RPETPEQILPATGESQSDTALFLASVSLALSALFVVKTKKD"
     gene            complement(23178..25337)
                     /gene="pbp1a"
                     /locus_tag="ACL3EZ_001344"
     CDS             complement(23178..25337)
                     /gene="pbp1a"
                     /locus_tag="ACL3EZ_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001040003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein PBP1A"
                     /protein_id="HGR0392907.1"
                     /translation="MNKPTILRLIKYLSISFLSLVIAAIVLGGGVFFYYVSKAPSLSE
                     SKLVATTSSKIYDNKNQLIADLGSERRVNAQANDIPTDLVKAIVSIEDHRFFDHRGID
                     TIRILGAFLRNLQSNSLQGGSTLTQQLIKLTYFSTSTSDQTISRKAQEAWLAIQLEQK
                     ATKQEILTYYINKVYMSNGNYGMQTAAQNYYGKDLNNLSLPQLALLAGMPQAPNQYDP
                     YSHPEAAQDRRNLVLSEMKNQGYISAEQYEKAVNTPITDGLQSLKSASNYPAYMDNYL
                     KEVINQVEEETGYNLLTTGMDVYTNVDQEAQKHLWDIYNTDEYVAYPDDELQVASTIV
                     DVSNGKVIAQLGARHQSSNVSFGINQAVETNRDWGSTMKPITDYAPALEYGIYDSTAT
                     IVHDEPYNYPGTNTPVYNWDRGYFGNITLQYALQQSRNVPAVETLNKVGLNRAKTFLN
                     GLGIDYPSIHYSNAISSNTTESDKKYGASSEKMAAAYAAFANGGTYYKPMYIHKVVFS
                     DGSEKEFSNVGTRAMKETTAYMMTDMMKTVLSYGTGRNAYLAWLPQAGKTGTSNYTDE
                     EIENHIKTSQFVAPDELFAGYTRKYSMAVWTGYSNRLTPLVGNGLTVAAKVYRSMMTY
                     LSEGSNPEDWNIPEGLYRNGEFVFKNGARSTWNSPAPQQPPSTESSSSSSDSSTSQSS
                     STTPSTNNSTTTNPNNNTQQSNTTPDQQNQNPQPAQP"
     gene            complement(25334..25930)
                     /gene="recU"
                     /locus_tag="ACL3EZ_001345"
     CDS             complement(25334..25930)
                     /gene="recU"
                     /locus_tag="ACL3EZ_001345"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HGR0392908.1"
                     /translation="MVNYPHKVSSQKRQTSLSQPKNFANRGMSFEKMINATNDYYLSQ
                     GLAVIHKKPTPIQIVQVDYPQRSRAKIVEAYFRQASTTDYSGVYNGYYIDFEVKETKQ
                     KRAIPMKNFHPHQIQHMEQVLAQQGICFVLLHFSSQQETYLLPAFDLIRFYHQDKGQK
                     SMPLEYIREYGYEIKAGAFPQIPYLNVIKEHLLGGKTR"
     gene            25996..26523
                     /locus_tag="ACL3EZ_001346"
     CDS             25996..26523
                     /locus_tag="ACL3EZ_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HGR0392909.1"
                     /translation="MATALVLGYSAFDLGLFSDKDPRLKLIKKAIRKDLEAMAADGVS
                     WLVFTGTLGFEYWVLEVAQEMKTEYGFQLATIFAFETHGENWNEGNQMKLSRFKQVDF
                     VKYAYPRYEHKGQLRDYQQFLLENTTSSYLFYDEENETKLAYFYQKMKNQEDYFIKRL
                     TFDQLNELAENFSEN"
     gene            26593..26922
                     /gene="gpsB"
                     /locus_tag="ACL3EZ_001347"
     CDS             26593..26922
                     /gene="gpsB"
                     /locus_tag="ACL3EZ_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HGR0392910.1"
                     /translation="MASIIFSAKDIFEQEFGREVRGYNKVEVDEFLDDVIKDYETYAA
                     LVKSLRQEIADLKEELTRKPKPSPVQAEPLEAAITSSMTNFDILKRLNRLEKEVFGKQ
                     ILDNSDF"
     gene            26943..27323
                     /gene="rnpB"
                     /locus_tag="ACL3EZ_001348"
     ncRNA           26943..27323
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="ACL3EZ_001348"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            27408..28565
                     /locus_tag="ACL3EZ_001349"
     CDS             27408..28565
                     /locus_tag="ACL3EZ_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HGR0392911.1"
                     /translation="MKKEFNLIATAAAGLEAVVGREVRELGYDCQIENGRVRFQGDVR
                     AIIETNLWLRAADRIKIIVGTFPAKTFEELFQGVFALDWENYLPLGARFPISKAKCVK
                     SKLHNEPSVQAISKKAVVKKLQKHYARPEGVPLMENGPEFKIEVSILKDVATVMIDTT
                     GSSLFKRGYRTEKGGAPIKENMAAAILQLSNWYPDKPLIDPTCGSGTFCIEAVMIARK
                     MAPGLRRSFAFEEWNWISDRLIQEVRTEAAKKVDRELELDIMGCDIDARMVEIAKANA
                     QAAGVAGDITFKQMRVQDLRSDKINGVIISNPPYGERLSDDAGVTKLYAEMGQVFAPL
                     KTWSKFILTSDEAFESKYGSQADKKRKLYNGTLKVDLYQYFGQRVKRQEVK"
     gene            28578..29948
                     /gene="mapZ"
                     /locus_tag="ACL3EZ_001350"
     CDS             28578..29948
                     /gene="mapZ"
                     /locus_tag="ACL3EZ_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mid-cell-anchored protein MapZ"
                     /protein_id="HGR0392912.1"
                     /translation="MSKKRRNRQKKEGQEPQFDFDEAKELTVGQAIRKNEEVEAGVLP
                     EDSILDKYVKQHRDEIEADKFATRQYKKEEFVETQSLDDLIQEMREAVEKSEASSEEV
                     PSSEDILLPLPLDDEEQGLDPLLLDDENPTEMTEEVEEEQNLSRLDQEDSEKKSKKGF
                     ILTVLALVSVIICVSAYYVYRQVARSTKEIETSQSTTANQSDVDDFNTLYDAFYTDSN
                     KTALKNSQFDKLNQLKTLLDKLEGSREHTLAKSKYDSLATQIKAIQDVNAQFEKPAIV
                     DGVLDANAKAKSDAKFTDIKTGNTELDKVLDKAISLGKSQQTSTSSSSSSQASSNTTS
                     EPKPSSSNETRSSRSEVNMGLSSAGVAVQRSASRVAYNQSAIDDSNNSAWDFADGVLE
                     QILATSRSRGYITGDQYILERVNIVNGNGYYNLYKPDGTYLFTLNCKTGYFVGNGAGH
                     ADDLDY"
     gene            30024..31448
                     /gene="gndA"
                     /locus_tag="ACL3EZ_001351"
     CDS             30024..31448
                     /gene="gndA"
                     /locus_tag="ACL3EZ_001351"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004616 - phosphogluconate dehydrogenase
                     (decarboxylating) activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HGR0392913.1"
                     /translation="MTKANFGVVGMAVMGRNLALNIESRGYTVAIYNRSKEKTEDVIA
                     CHPEKNFVPSYDVESFVNSIEKPRRIMLMVQAGPGTDATIQALLPHLNKGDILIDGGN
                     TFYKDTIRRNEELANSGINFIGTGVSGGEKGALEGPSIMPGGQKEAYELVSDVLEEIS
                     AKAPEDGKPCVTYIGPDGAGHYVKMVHNGIEYGDMQLIAESYDLMQHLLGLSAEDMAE
                     IFTEWNKGELDSYLIEITADILSRKDDEGQDGPIVDYILDAAGNKGTGKWTSQSSLDL
                     GVPLSLITESVFARYISTYKEERVYASKVLPKPAAFNFEGDKAELIEKIRQALYFSKI
                     ISYAQGFAQLRVASKENNWNLPFADIASIWRDGCIIRSRFLQKITDAYNRDADLANLL
                     LDEYFLDVTAKYQQAVRDIVALAVQAGVPVPTFSAAITYFDSYRSADLPANLIQAQRD
                     YFGAHTYQRKDKEGTFHYSWYDEK"
     gene            31460..32149
                     /locus_tag="ACL3EZ_001352"
     CDS             31460..32149
                     /locus_tag="ACL3EZ_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000518023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGR0392914.1"
                     /translation="MGKRILLLEKERNLARFLSLELQKEQYRVDLVEEGQKALSMALQ
                     TDYDLMLLNVNLGDMMAQDFAEKLSRTKPASVIMILDHWEDLQEELEVVQRFAVSYIY
                     KPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
                     REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIK
                     TVRGVGYTMQE"
     gene            32247..33143
                     /locus_tag="ACL3EZ_001353"
     CDS             32247..33143
                     /locus_tag="ACL3EZ_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HGR0392915.1"
                     /translation="MKLLKKMMQVLLAVFFFGLLATNTVFANTTGGRFVDKDNRKYYV
                     KDDHKAIYWHKIDGKTYYFGDIGEMVVGWQYLEIPGTGYRDNLFDNQPVNEIGLQEKW
                     YYFGQDGALLEQTDKQVLEAKTSENTGKVYGEQYPLSAEKRTYYFDNNYAVKTGWIYE
                     DGNWYYLNKLGNFGDDSYNPLPIGEVAKGWTQDFHVTIDIDRSKPAPWYYLDPETGIM
                     RTGWQYLGNNWYYLRSSGAMATGWYQEGSTWYYLNAGNGDMKTGWFQVNGKWYYAYSS
                     GALAVNTTVDGYYVNYNGEWVR"
     gene            complement(33261..34493)
                     /locus_tag="ACL3EZ_001354"
     CDS             complement(33261..34493)
                     /locus_tag="ACL3EZ_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HGR0392916.1"
                     /translation="MKLFWTNNIYRQLLLNSCFSSFGDSIFYLAIINYVAQYNFAPLA
                     ILLISISEMVPLLSQLFLGILGDFQENRVKHALWIAKIKILLYAILTVFLVLSPFSLV
                     SVIMIVIINLISDTLSYLSAYMMNALYISVIKDDLHDAMGFRQSLMRVVHIVANLAGA
                     FLINVMSIQTISLINTLTFVIAFLGLYVIRHTLYEVEKRIEMSHTALSFKKYFQHLKQ
                     SLAVLLRLKDTVILLFLTTSMIAILDVSPRLIALRFIQQTLAQLSIGQLLAMLSIIIS
                     CGAILGNMTSSNLFKNIRFTHLLVFCEISLLALITSILCQAYIVIFMTSFISSTIIGI
                     LSPRLQAAVFAHIPSDKMGTVGSALSTVDILAPSLLSLLALSIASGVSVQLALIFLYL
                     ILIALIFCQWLVKFNTHN"
     gene            complement(34652..35122)
                     /locus_tag="ACL3EZ_001355"
     CDS             complement(34652..35122)
                     /locus_tag="ACL3EZ_001355"
                     /inference="COORDINATES: protein motif:HMM:NF017000.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0031179 - peptide modification [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lanthionine synthetase LanC family protein"
                     /protein_id="HGR0392917.1"
                     /translation="MTILLKLSSTIVYGEIYHYFLQRDTAKESILDYSFAHGYCEIAY
                     ALFAYSKVLEPSMFYNDLHTFHAELKKLLEKVTSNTENLGNLQLSWCEGISGIILYLC
                     MYDCDGNKDIISKYQEFVFNHHLKMMTGYCHGITSLLQTTVYNQNKLLMKKSNR"
     gene            complement(35022..35411)
                     /locus_tag="ACL3EZ_001356"
     CDS             complement(35022..35411)
                     /locus_tag="ACL3EZ_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0031179 - peptide modification [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lanthionine synthetase LanC family protein"
                     /protein_id="HGR0392918.1"
                     /translation="MYPPELDSKILSIIKKAVTIRTTHTYEYQYSLLFGDAGYLWLLL
                     HLFSISKNQYYLQLANVTAKKLIENYDTLEEIDFALGKSGVLLSLIKYYQFTNDNTLK
                     TFIHNSIWGNLSLFPTKRYSQRKHFRL"
BASE COUNT        11050 a         6290 c         7787 g        10614 t
ORIGIN      
        1 ggtcttgttc ataattagat tgaaactaga atagtacacc tctgcttcta aaacattgtt
       61 agaaatcgat ttgactgtcc tgatcgtttt gtcatgttct tatttcattt tactatattt
      121 ttggttcgcg ggaagtctac taagatactt aaagatgcag atagtaaaaa aagatgtaga
      181 cattaccgta aaaaagtgat ataatcgtat ggtgttcaag gtataggtgt taatcatgag
      241 tagacgtttt aaaaaatcac gttcacagaa agtgaagcga agtgttaata tcgttttgct
      301 gactatttat ttattgttag tttgtttttt attgttctta atctttaagt acaatatcct
      361 tgcttttaga tatcttaacc tagtggtaac tgcgttagtc ctactagttg ccttggtagg
      421 gctactcttg attatctata aaaaagctga aaagtttact atttttctgt tggtgttctc
      481 tatccttgtc agctctgtgt cgctctttgc agtacagcag tttgttggac tgaccaatcg
      541 tttaaatgcg acttctaatt actcagaata ttcaatcagt gtcgctgttt tagcagatag
      601 tgatatcgaa aatgttacgc aactgacgag tgtgacagca ccgactggga ctgataatga
      661 aaatattcaa aaactactag ctgatattaa gtcaagtcag aataccgatt tgacggtcga
      721 ccagagttcg tcttacttgg cagcttacaa gagtttgatt gcaggggaga ctaaggccat
      781 tgtcttaaat agtgtctttg aaaatatcat cgagtcagag tatccagact acgcatcgaa
      841 gataaaaaag atttatacca agggattcac taaaaaagta gaagctccta agacgtctaa
      901 gaatcagtct ttcaatatct atgttagtgg aattgacaca tatggtccta ttagttcggt
      961 gtcgcgatca gatgtcaata tcctgatgac tgtcaatcga gataccaaga aaatcctctt
     1021 gaccacaacg ccacgtgatg cctatgtacc aatagcagat ggtggaaata atcaaaaaga
     1081 taaattaacc catgcgggca tttatggagt tgattcgtcc attcacacct tagaaaatct
     1141 ctatggagtg gatatcaatt actatgtgcg attgaacttc acttctttct tgaaattgat
     1201 cgatttgttg ggtggggtag atgtttataa tgaccaagat tttacatctc tacacgggaa
     1261 gttccatttc ccagttggaa atgtccactt agattctgag caggctctgg gatttgttcg
     1321 tgagcgctat tccctagcgg atggtgatca tgaccgcggg cgcaatcaac aaaaggtgat
     1381 tgcggccatc cttcaaaaat taacttcgag cgaagcgctg aaaaattata gtaggatcat
     1441 tgatagcttg caagattcta tccaaacaaa catgccactt gagaccatga taaacttggt
     1501 caatgctcag ttagaaagtg gtggaacgta caaagtgaat tcgcaagact tgaagggtat
     1561 gggacggacg gatcttcctt cctatgcgat gccagatagt aacctctata tgatggaaat
     1621 taacgacagt agccttgcat ctgtcaaaac tgctattcag gatgtgttgg agggcagatg
     1681 aaatgattga tattcattcg cacatcgtct ttgatgtaga tgatggtccc aagtcaagag
     1741 aggaaagcaa ggctctcttg gcagaatcct acaggcaggg ggtgcgaacc attgtctcta
     1801 cctctcaccg tcgcaagggc atgtttgaaa ctccggaaga gaagatagca gaaaactttc
     1861 ttcaggttcg ggaaatagct aaggaagtgg cgagtgactt ggtcattgct tacggggctg
     1921 aaatttacta cacatcagat gttttggata agctggaaaa aaatcggatt ccgaccctca
     1981 ataatagtcg ttatgccttg atagagttta gtatgaacac cccttatcgc gatattcata
     2041 gtgccttgag taaaatattg atgttgggaa ttactccagt cattgcccac attgagcgct
     2101 atgatgcact tgaaaataat gaaaaacgcg ttcgagagct gatcaatatg ggctgttaca
     2161 cgcaagtaaa tagttcacat gtcctcaaat ccaaactttt tggagaacgt tataaattca
     2221 tgaaaaaaag agctcagtat tttttggagc gtgacttggt tcatatcatt gcaagtgata
     2281 tgcataatgt ggacagcaga cctccccata tggcagaagc atatgacctt gtttcccaaa
     2341 aatacggaga agcgaatgct caggaacttt ttatagataa tcctcgaaaa attgtaatgg
     2401 atcaactaat ttaggagaaa tgatgaaaga acaaaacacg atagaaatcg atgtatttca
     2461 attacttaaa accttgtgga aacacaagct aataatttta ttagtggcac ttgtgacagg
     2521 ggcgggagct tttgcatata gcacttttat tgttaagcca gaatatacaa gcaccacgcg
     2581 tatttacgta gtcaaccgta atcaaggaga taagccggga ctgacgaatc aggacttgca
     2641 ggcaggaact tatctggtaa aagactaccg cgaaattatc ctttcgcaag atgtattgga
     2701 aaaggtagcg acaaatttga aattggatat tccagcaaaa acgttaacta gcaaagtgca
     2761 agtgactgta ccagccgaca ctcgtatcgt ctcaatctct gtcaaggata aacaaccaga
     2821 ggaagccagt cgcattgcta attctctacg agaagttgct gcagaaaaga tcatcgctgt
     2881 aacgcgagta tctgatgtaa cgacgcttga agaagcgcga ccagctatga ctccctcttc
     2941 tccaaatgtt cgacgcaaca ccttagttgg ttttcttgga ggagccgccg taacagtaat
     3001 tactgttctt ttgattgagt tgttcgatac ccgtgtaaaa cgtcctgaag atgttgaaga
     3061 tgtactgcaa atgccacttc taggagtcgt tccagatttt gataaaatga aataggagga
     3121 agttatgcca acgttagaaa tctcacaggc gaaattagaa cttgtgaaaa aggcagagga
     3181 atattataat gctttgtgca cgaacctaca gttaagtgga gatgatttga aagtattttc
     3241 tatcacttct gtgaaagcag gagaaggaaa aacaacgact tccaccaata tcgcttgggc
     3301 ttttgcgcgt gcaggttaca aaacgcttct gattgatgca gacatgcgta actccgttat
     3361 gtcaggtgtc tttaaatcaa gggaaaggat tactggacta acagaatttc tatcagggac
     3421 aacagacctg tcacaggggc tttgcgatac caatattgag aatctctttg tgattcaggc
     3481 tggctctgtg tcaccaaatc cgacagccct tcttcaaagt aagaatttca gtacaatgct
     3541 tgaaaccttg cgtaaatatt ttgactatat cgtcgtagac actgcccctg tcggtgtcgt
     3601 gattgatgcg gctatcatta tgcagaaatg tgatgcttct attttagtga cgaaggcagg
     3661 tgaaacaaaa cgacgggatc ttcaaaaagc gaaagaacag ttggaacaaa ctgggaagtc
     3721 gtgtttagga gttgtgttga ataaactcga tacttcagta gagaaatacg gttcttatgg
     3781 gagttatggg aattacagga aacagaaaaa ataggttgag ggatagaaat gagtgaaaaa
     3841 ctagcaaagc cttcagtagc catagtccag agttttcttg ttattttatt gacttatcta
     3901 cttagcgctg tgagagaaac agagattgtt tcaacaacag ctattgtact ttatatcctc
     3961 cactattttg tcttttatat cagtgattat ggacggaatt tctttaaaag gggatatttg
     4021 attgaacttg tccagacatt gaaatatatc ctattctttg cgctagcgat tagtatttct
     4081 aattttttct tagaagatcg atttagtatt tccagaagag gcatgattta cttcctctta
     4141 ttacatgttt tcttagtcta tgtgctaaac ccatttatca agtggtattg gaagcgggct
     4201 tatcccaact ttaaaggaag taagaagatt ctcctactta cagcaacttc tcgtgttgaa
     4261 aaggtactgg atagactaat agaatcagat gatgttgttg gggagttggt agccgtcagt
     4321 gttttagata aaccagattt tcagcatgat gatttaaagg ttgtagcaga gggggagata
     4381 gtaaattttg cgactcatga ggtggtcgat gaagtcttta tcaatcttcc aagtgaaaaa
     4441 tacaatattg gagagcttgt ctctcagttt gaaacgatgg gaattgatgt aacagtcaat
     4501 ctaaatgctt tcgattgggc acgtaacaag caaatttgtg agatggcagg actaaatgtt
     4561 gtgacttttt ctacaacatt ttataagact agccatgtga ttgctaagcg ggttattgat
     4621 attgtcggtt ccctggtagg tttgatatta tgtggtctag tcagtattgt gctggttcct
     4681 ttgattcgaa aggatggggg ttctgctttt tttgctcaga cgcgtatagg aaaaaatggc
     4741 cgccatttta ctttttataa gtttcgctct atgtgtgtgg atgctgagga gaaaaaaaga
     4801 gaactcatgg aacaaaatac catgcagggt ggaatgttta aggtggacga tgatcctcgt
     4861 atcacgaaaa ttggtcattt tatacggaag acgagcttgg acgagctacc acagttttat
     4921 aatgttctaa agggagatat gagtttggta ggtacacgac caccaacagt ggacgagtat
     4981 gagcactata ccccagaaca aaaacgtcgc ctaagtttta aacctggcat aacaggttta
     5041 tggcaggtca gcggacgaag tgaaatcaaa aatttcgatg aagttgtcaa attagatgtg
     5101 gcctatattg atggttggac aatctggaaa gatattgaaa ttttattgaa gacagttaag
     5161 gttgtattga tgaaggatgg agcgaaatag ttcatatgaa tgagagaatt caaatattag
     5221 gaattactat agatccatta acgatgaaag aaacagtgga tgctgttgaa cagtatgttt
     5281 taaagaagca ccctttgcac ttgatgggag ttaacgcgga taaaattaat cagtgctatg
     5341 aagatgagaa aatcaaaaaa atcgttaatg aatcaggaat aattaatgcc gacggtgctt
     5401 cagtagtttt agcgagtaag tttttaggaa caccagttcc tgagcgagtt gctggaatag
     5461 acttgatgaa acatttacta gagttgtcta atgaaaaagg atactcggtc tacttttttg
     5521 gagcaaaaga agacgtttta caagatatgt taaaaatttt tgaagaaaga tatccagctc
     5581 taaatgttgt tggctataga aatggatatt tttcgcctga agatgaaaaa catattcagg
     5641 aagatattaa agagaaaaaa ccagattttg tgtttgtagg aattacttct cctaagaaag
     5701 aatatattat ccaatcattc atggataatg gaattaatgc tgtgtttatg ggggttggtg
     5761 gaagttttga tgtactatca gggcatatca aacgagctcc attatggatg caaaatgctc
     5821 acctagagtg gttgtttcgt gtggcaaatg agcctaaacg tctctttaag cgttattttg
     5881 tagggaatgt ttcatttata agaaaagttt taagagcgaa aaggggatat aaactttgaa
     5941 ccaaacagaa atagttaaat tgattcagaa agttgaattg gatgctataa aagagtttca
     6001 aaaaatttgt aaagagaaca atatagattt cttccttcgt ggggggagtg tacttggggc
     6061 agtcaaatat gatggcttta ttccatggga tgatgacatg gatattgctg tgcctcgtga
     6121 aggctacgat aaacttccag gtatctttaa ggatagaatt atcgcaggca aatatcaggt
     6181 tcttgcttat caatattgcg atactttaca ttgctacttt cctcgcttat tccttttaga
     6241 agatgaaaga aaacgtttgg gattgccacg aaataccaat ttaggtttgc atttgattga
     6301 tatcattcct ttggatggtg ccccaaatca ttcattttta agaaagcttt acttcggtaa
     6361 agtatactgg tatcgttttt tagcaagttt aggaactacc tatgttggag accatgtgga
     6421 tatgcattcc gctaagcaaa aactaatcat tggtttcttt aaaaagctag gatttgcaaa
     6481 actattccct caaaattatg tgtacagacg cttggataat ctctataaaa agtatgattg
     6541 gaaaaagcag aagtatgctg ggacaattaa tgcatctctg tttgccaaag aagtcatgcc
     6601 agtagagatt tggggagaag gagtagagaa gccttttgag gatgccttct ttaaagttcc
     6661 cacggagtat gaccgctatc tgaaaagact ttacggagaa aactatcttc acgaagagcc
     6721 tagtgatgat gaaaagaaat cgcatttagg aggacaataa tttgttttgt tatattattt
     6781 tgcattacaa agtcttagag gaaactattt cttgtgttaa atcaataaaa gaaggcaatt
     6841 ccaatacaaa gcagatcgtt attattgata atttttctaa taacggtacg ggtgaaaaac
     6901 tacaagagct gtatgagtca gattcagaga ttgatgtctt gattaaccat gaaaatgctg
     6961 gtttcgctcg aggtaataat gtagcatatc agtttgctaa ggaaaagtac aaacctgatt
     7021 ttatggttat catgaataat gatattgaga tagaaacaga agagtttgaa aaaatcgtga
     7081 cagatatcta tcggaaggaa aaattccatt tgttaggacc agatatcttt tcgacgacgt
     7141 atcagcttca ccaaaaccca aaacggttga cgcattatac ttatgaagag gttaaggctc
     7201 tcaatgaaaa atttaagaaa gggagccaag ttagtctagc attaaaaatt aaatgttggt
     7261 tgaagtctag taaagttctt cggacagcaa tctatcaaaa taggcgtaaa aagaaatcag
     7321 tagactatag aaaacaggta gaaaacccaa ttcttcatgg ttcgtttatt gtatattcta
     7381 gagattttat tgagaaagag gagtatgctt ttaatcccaa taccttcttc tattatgaaa
     7441 cagagatatt agattatgaa gctgagttaa aaggatataa gagaatttat acaccgaaga
     7501 ttaaggtctt gcaccatcaa aatgttgcaa ccaatcaagt ctatacaaac ttagtagaaa
     7561 aaaccttgtt ttcaaacaaa tgcaactttg aatccactag ttattttttg aagttgatga
     7621 aagaaaacga gggtgtgtaa atgacttatt tatttttact ctgcctgacc ttattcttat
     7681 taactttctt ctattttttt gctttcaatc aagatttgat agctccgcca gttgtcatgt
     7741 ctgttatgtt tctcattagt tctgtatttg cccttattaa tgtgcaaaac tggaatattg
     7801 agtatagtgg tttagcttat cttttgatta ttagtggcat tattgttttt tcaatgcctc
     7861 tcttggctct taattcgcct attctaaata ccaagattaa agtgacggat cggctcattg
     7921 atatccaatt ctggaaaata gctcttacta ttatagttga cctcattatt ctatatcttt
     7981 ataggagaga gattcataat cttgcactta gccatggtta tacgggttca aattttcagt
     8041 ggttctttag aaatgctacc agttatgaag gtgagctaac agtgcgaact tcgattcggg
     8101 tcctcattcg tatcattgac gtatctgctt atatttttgg atatactttt attaataatt
     8161 tcttcattta tagtcataaa cgctctaaag atttactgct cttagttcca ttcttgattt
     8221 ttatttctaa aaccttatta tctgggggta gattggatat tataaaaatt ttaattgcgt
     8281 atgttgtaat ggcctatatt cagcaaaaac gaaaagttgg ctgggataag gtcatctccc
     8341 ataaatatat gagacttggt tttgtaggct tgatagctgg gattcctacc ttttactatt
     8401 ctttattctt atctggacgt tctacgacta gaactgtatt tgaaagtatt tcaacctatt
     8461 taggaggttc gattcagcat tttaatcagt atattcaaaa tcctattgga gtagctgagg
     8521 tttttggcga tgagtcattt gtagctatta tgaatatttt gggtaatctt ggctttgtca
     8581 attacaatag taccgttcac ttagaatttc ggcagttagg gattactatg ggtaacgttt
     8641 atactttctt tagaagaccc tggcatgact ttgggttagt cggtatgtat atcttttcct
     8701 ttgttgtcgg tgtgtttttt gctatttttt atttgaaatt aagaaagagc cgtgctggtt
     8761 ttaaattgga tattcataca attatttact cttatttctt ttattggatt tttttatcgt
     8821 ccattgagca atactcgttt acaacaatca gtttgtttac acttgtattt atagtcttgg
     8881 tttacctaat ggctttcttc tattggaatt tggatttcca cagaggaaaa ctagtaatta
     8941 aactctctga cacaagtatt aaatcggaaa actgaaaaca ataaaaatag agaggatagt
     9001 tgatgaatag caaaattaaa aatatactaa ctaatttctc ttatgtcatt tcttcaaatc
     9061 ttttgacagt cttgacctct tccttggttg tcttaatttt ccccaaatta atgggggtaa
     9121 cagagtacag ttactggcaa ctttatattt tttatctgac ctatatcggt tttttccact
     9181 tgggttggat tgatgggatt tatcttaaat atggtggctt agaatataat aatttagata
     9241 gaaaacagtt ttattctcag atgattctat tttctagctt cttaatgatt atctccttgc
     9301 tattgtttgg tttaaatgta ttagctgtaa cagattcgaa tgcacgatat atttataata
     9361 tgactattat aagtatgata atcacaaatt taagaacgct ctacgtgtat gttttgcaga
     9421 tgacaaaccg cttgaaggat agttccatca ttctactcag tgatcgcgtt ttatatgtgc
     9481 tccttttatt cctgtttatt gtatttggtt ggcatgaata caaggttatg attttggcag
     9541 atattctagg tcgatcattt tctctcatac tttccttctg gatttgtaaa gatattgtgt
     9601 ttcagccttt gtcaaaattc atctttaata taaaagagtc ttttgataat atccgagttg
     9661 gtatcaattt aatgttatcc aacatcgcaa gtagtttgat tatcggtatt gttcgtctag
     9721 gaatccaatg gaactggaat atcgaaacat tcgggaaagt atctctgacc ttgagtgttt
     9781 ccaatctatt gatgactttc attaatgcca ttggactagt cgtctttccg ctattaagac
     9841 gaacaaaagc agaaaactta cctaagattt attctaattt aagaaacgtt ttgatgctta
     9901 tcatgttcgc gattttgctc atttactatc ctttaaaaat tgtattagac ctctggttgc
     9961 cagcctatca agatgccttg attttcatga cccttatttt ccctatgtca gtctatgaag
    10021 ggaaaatggc attggtcatt aatacttact taaaggcatt aagaatggaa agagatatcc
    10081 ttagagtcaa tgccttagta atgttgatca gtatgggagt gaccctggtt acaacatacc
    10141 tgttaaatag tttggagctg actgttgtat cgatagttgt tttgctagct ttgagaagta
    10201 tcatagccga attaattctg tctaaaaaac tggatgtttc ggttaagaag gatattgtat
    10261 tagaatttct tttgacgctt gtctttattt cttcaagttg gtatttgccg attgggctgg
    10321 cagtaattgt ctacacaata gcctacggtt tatatctcta tttgaaacac gaagatatca
    10381 aaacctattt agcttacttt aaagctagta aaaaaacatc aaattaaaaa attatataat
    10441 gattaagtgg tagattctat ttctaccgtt ttagatattc gggaggtaat gatgaaaaaa
    10501 attatgttag tattcggtac acgtccggaa gccatcaaaa tgtgtccatt agtcaatgag
    10561 ttgaaaaaac acgaagatat ggaaacaatt gtgtgtgtta ctggacaaca caaagagatg
    10621 gttagtcctg ttttagattt atttggtgtt gtaccagatt atgatttaga aattatgaag
    10681 gctaaccaaa ccttgttctc tatcacaact agtatcttgg aaaagataaa accagtttta
    10741 gagaaggaac aaccagatat tgtcctagtt cacggtgaca ctacgacaac ttatgcagca
    10801 gccttggcag cattctattt gggaattaaa gtaggacatg ttgaagctgg tttgcgaacg
    10861 tacaatttac aaagtccatt tcctgaagaa tttaacaggc aatcgacatc aatcattgca
    10921 acttaccatt ttgctccaac tgagttggct aaagaaaatc tcttaaaaga aggtagagag
    10981 aatgtttatg tgactggaaa tactgtcatt gatgctctta caactactgt tcaagaggat
    11041 tatacacaca ctcatttaga tttaaacgct aacaatcgtc tcatcttatt gactgctcat
    11101 agacgcgaaa atctcggcga accgatgaga catatgttta gagcagttaa acgagtattg
    11161 aatgaatacg aagatgttaa agtcatttat ccaattcata agaatccttt ggtacgtgaa
    11221 acagctgcag agatctttgg agatacagaa cggattcaaa ttattgaacc tttggatgtt
    11281 cttgatttcc acaacttcat gaaccaaagt tatatgattt taacagattc tggcggagtt
    11341 caggaagaag caccttcttt aggaaaacct gtattggtta tgcgcgatac tactgaaaga
    11401 cctgaaggag tagcggcagg aaccttgaaa ttagtaggaa ctgacgaaga aacaatttat
    11461 caaaacttca aactacttct agatgattct ggagaataca aaaaaatgag tcaggctagc
    11521 aatccatacg gtaatggtga tgctagtcaa cagattgttc agattttgcg tgggatttaa
    11581 gaagattctc taaaagagtc taagaggaat ccactccaca aacataaaac tcttatgcta
    11641 tcatttatga ttgagataga ctcataactt aatattttta tcctaagaaa attcgttcat
    11701 attcaatatg aatgaaaaac aacgaagaaa ggttatttca ttatgaaagg tattattctt
    11761 gcaggcggct caggtacccg cctgtaccca cttactcggg ctgcgtcaaa acagctgatg
    11821 ccggtttatg ataaacctat gatttattat ccgttgtcga cattaatgtt ggctggaatt
    11881 aaagatattt tgattatctc aactcctcaa gatttgcccc gttttaagga cttgctcttg
    11941 gatggttccg aatttgggat caagctttcc tatgcggaac aacctagtcc cgatggactt
    12001 gctcaggctt ttcttatcgg tgaagaattt atcggtgacg atagcgttgc cttgatttta
    12061 ggcgacaata tctaccatgg tcctggtctg agcacaatgc ttcaaaaagc agccaagaaa
    12121 gagaaaggtg cgactgtttt tggctaccaa gtgaaggatc cagagcgttt tggtgtggtt
    12181 gagtttgata cagacatgaa tgctatttct atagaagaaa aaccggagta tcctcgctcc
    12241 aactatgcag tgacaggact gtatttctat gataatgatg ttgtggagat tgctaaacag
    12301 atcaaaccta gtgctcgtgg cgagttagaa attacagacg ttaacaaggc ttacctaaat
    12361 cgtggtgacc tttctgttga gctgatgggg cgtggttttg cctggttgga tacgggaacc
    12421 catgaaagct tgctagaagc ttctcagtat attgaaacgg ttcagcgtat gcagaacgtt
    12481 caagtggcaa atctagaaga aatttcctat cgtatgggct acattagtcg tgaagacgtg
    12541 ctggaattgg ctcagcctct taagaaaaat gaatacggac aatatttgct ccgtttgatt
    12601 ggagaagcat agatgtcaga taattttttt ggaaagacac ttgtggtacg caagattgat
    12661 gctataccag gactgctaga gtttgacatt cccgttcatg gagacaatcg tggttggttt
    12721 aaggaaaatt tccagaagga aaagatgcta ccgcttggtt ttcctgaaag cttctttgct
    12781 gcagggaaac tgcaaaataa cgtcagcttt tctcgcaaaa atgttcttcg aggactccat
    12841 gctgaacctt gggacaagta tatctctgtt gcagacgatg ggaaggtttt aggatcttgg
    12901 gtagatttgc gtgaaggcga gacctttgga aatgtttacc agacagagat tgatgctagc
    12961 aagggaattt ttgtccctcg tggcgtagcc aacggttttc aagtcctctc agatacagtt
    13021 tcctatagct atctggtcaa tgactactgg gctcttgaac tcaaacccaa atatgccttt
    13081 gttaactatg ctgacccagc attgggaatt gagtgggaaa acctagcgga agctgaggtt
    13141 tcagaggcag acaaacacca tcctctatta agggatgtca aaccacttac gaaagacgag
    13201 ttgtaaaagg aaacattatg actgaataca aaaaaattat cgtgacaggt ggagctggtt
    13261 ttatcggttc taactttgtc cactatgttt acaataactt tccagatgtc catgtgacag
    13321 tgctggacaa gctgacttat gcaggtaatc gtgccaatat cgaggaaatt ttaggcgacc
    13381 gtgttgagtt ggttgttgga gatattgctg atgcagcctt ggtagacaag ttggcggctg
    13441 aagcggatgc tatcgttcac tatgcggcag aaagccacaa tgataactcg ctcaatgacc
    13501 cgagtccatt tatccacacc aactttatcg gaacttacac acttttagaa gcggctcgta
    13561 aatacgacat tcgtttccac catgtatcga ctgatgaagt ctatggtgac ctgcctctgc
    13621 gtgaagattt gccaggtcat ggggaaggcc taggtgagaa atttaccgct gaaaccaagt
    13681 acaatccaag ctcgccttac tcatcaacca aggctgcttc agacttgatc gttaaagctt
    13741 gggtgcgctc atttggtgtt aaagcaacga tttctaactg ttcaaacaac tatggtccat
    13801 accagcatat cgagaagttc attccgcgcc agattacgaa tatcttgagc ggtatcaagc
    13861 caaaactcta cggagaaggt aagaatgtgc gtgactggat tcacaccaat gaccattcat
    13921 caggcgtttg gacgattctg accaagggtc aaatcggtga aacttacttg atcggtgctg
    13981 acggtgagaa gaacaacaag gaagtgttag agctcattct caaggagatg gggcaacccg
    14041 ctgacgctta tgaccatgtg accgatcgag ctggtcacga cttgcgttat gcgattgatg
    14101 ctagcaagct ccgtgatgag ttggggtgga agccagagtt taccaacttt gaagcaggcc
    14161 tcaaagagac catcaagtgg tacacagata accaagactg gtggaaatct gaaaaagaag
    14221 cagtagaggc taactatgct aaaacgcaac aagtgattaa ataataagat actaaaaaag
    14281 caagagacct cgaggtctct tgcttttcta gtatgtagta agcttttatt ttcttacttc
    14341 ttgtttataa aactctttaa gggcatcttg ccaggttggg atgacgaaac ctgttgcctt
    14401 tgcctttgcc aaactcatag ttgagttgag aggtcgttta gccttagcgg ggaacttgct
    14461 agagtctact ggcactactt caacatcact gtccttaaga atctcgctag caaagtcata
    14521 ccaagtggtg tcttcagctg cgtcatttga taagtgatag tagccatact ctttttgatt
    14581 ttcagtcaca taggtcatga attcggccaa ggtccgtgtc caagttgggc gaccgtattg
    14641 gtcgttgacc actgtgagcg ttttatgggt tttggctagg ctttgcatgg taaagacaaa
    14701 gttttttcca taatttccaa aaacccaagc agtacgaatg atgtaatgct gtgacgtaag
    14761 gttttcaaca agttcttctc ccattcgctt ggtacgtccg tactctgttt gcggatcagg
    14821 tatgtcatcg acttcccact cttgtcctac tggtttcttt ccatcaaaga cgtagtctgt
    14881 tgagatatag accagaatag ctccgtattt ctcagaggcc ttggctacat tttcagttcc
    14941 agttacgttg atggcaaaat ccagttcttt cccttcatct tcggctgcat caacagcagt
    15001 gtaggctgca caatgataga ctagagttgg cttaacctca gcaaagactt tttcaaccat
    15061 ttcagaatta gtgatatcca tttcggtcac atccactgca acatagtcca catttcgctc
    15121 atctagtaaa taacgtagtt cggtaccaag ttgaccattt gcacctgtaa ttaagatcat
    15181 atttttctcc ttgatagttc ttatacttaa ttatatcaaa aatatagaaa aatcggtttt
    15241 tagtgaaccc ttttttggta taaactttgt tagtgaagcg caagagagcc gaatagttat
    15301 tactttagaa tatccttaaa agtatttttc agaatttacc aaattaatta aaaaattcag
    15361 aaaattatat tgacatctct ctgaaaagag tctataatag agagaaagtt ttaaaggaga
    15421 agatgatgaa aagttcaaaa ctatttgccc ttgcgggtgt aaccttattg gcggcgacta
    15481 ctttagctgc atgctctgga tcaggttcaa gcactaaagc tgagaagaca ttctcataca
    15541 tttatgagac agaccctgat aacctcaact atttgacaac tgctaaggct gcgacagcaa
    15601 atattaccag taacgtggtt gatggtttgc tagaaaatga tcgctacggg aactttgtgc
    15661 cgtctatggc tgaggattgg tctgtatcca aggatggatt gacttacact tatactatcc
    15721 gtaaggatgc aaaatggtat acttctgaag gtgaagaata cgcggcagtc aaagctcaag
    15781 actttgtaac aggactaaaa tatgctgctg ataaaaaatc agatgctctt taccttgttc
    15841 aagaatcaat caaagggttg gatgcctatg taaaagggga aatcaaagat ttctcacaag
    15901 taggaattaa ggttctggat gatcagacag ttcagtacac tttgaacaaa ccagaaagct
    15961 tctggaattc taagacaacc atgggtgtgc ttgcgccagt taatgaagag tttttgaact
    16021 caaaagggga tgattttgcc aaagcgacgg atccaagtag tctcttgtat aatggacctt
    16081 atttgttgaa atccattgtg acaaaatctt ctgttgaatt tgcgaaaaat ccgaactact
    16141 gggataagga caatgtgcat gttgacaaag ttaaattgtc attctgggat ggtcaagata
    16201 ccagcaaacc tgcagaaaac tttaaagatg gtagccttac agcagctcgt ctctatccaa
    16261 caagtgcaag tttcgcagag cttgagaaga gtatgaagga caatattgtc tatactcaac
    16321 aagactctat tacgtatcta gtcggtacaa atattgaccg tcagtcctat aaatacacat
    16381 ctaagaccag cgatgaacaa aaggcatcga ctaaaaaggc tctcttaaac aaggatttcc
    16441 gtcaggctat tgcctttggt tttgatcgta cagcctatgc ctctcagttg aatggacaaa
    16501 ctggagcaag caaaatctta cgtaatatct ttgttccacc aacatttgtt caagcagatg
    16561 gtaaaaactt tggcgatatg gtcaaagaga aattggtcac ttatggggat gaatggaagg
    16621 atgttaatct tgcagattct caggatggtc tttacaatcc agaaaaagcc aaggctgaat
    16681 ttgctaaagc taaatcagcc ttacaagcag aaggtgtgac attcccaatt catttggata
    16741 tgccagttga ccaaacagca actacaaaag ttcagcgcgt ccaatctatg aaacaatcct
    16801 tggaagcaac tttaggagct gataatgtca ttattgatat tcaacaacta caaaaagacg
    16861 aagtaaacaa tattacatat tttgctgaaa atgctgctgg cgaagactgg gatttatcag
    16921 ataatgtcgg ttggggtcca gactttgccg atccatcaac ttaccttgat atcatcaaac
    16981 catctgtagg agaaagtact aaaacatatt tagggtttga ctcaggggaa gataacgtag
    17041 ctgctaaaaa aataggtcta tatgactacg aaaaattggt tactgaggct ggtgatgagg
    17101 ctacagatgt tgctaaacgc tatgataaat acgctgcagc ccaagcttgg ttgacagata
    17161 gtgctttgat tattccaact acatctcgta cagggcgtcc aatcttgtct aagatggtac
    17221 catttacaat accatttgca ttgtcaggaa ataaaggtac aagtgaacca gtcttgtata
    17281 aatacttgga acttcaagac aaggcagtca ctgtagatga ataccaaaaa gctcaggaaa
    17341 aatggatgaa agaaaaagaa gagtctaata aaaaggctca agaagatctc gcaaaacatg
    17401 tgaaataact gttgcaaaat ataagaaagg atttagtatt tctcttgaat gctgaatcct
    17461 tttttacatt tgtaaagaaa gattctaaat gtactgaccc ccaaaagttg gagcctcttt
    17521 ttgtcagaat agagaaaatt tttgttaatt ttacttgttt cctattgctt tctcagttat
    17581 tatttgttat attaaaagta taattatttt tatttatcag ggttaagcat tgcactttca
    17641 gaggaaggag tattttttaa aaaggaaatg taaacgcttg ctaaaaaatg aaaggattta
    17701 gaagtttatg aataaaggat tatttgaaaa acgttgtaaa tatagtattc ggaaattttc
    17761 attaggtgtt gcttctgtta tgattggagc tgcattcttt gggacaagtc cggttcttgc
    17821 agatagcgtg cagtctggtt ccacggcgaa cttaccagct gatttagcta ctgctcttgc
    17881 aacagcaaaa gagaatgatg gacgtgattt tgaagcgcct aaggtgggag aagaccaagg
    17941 ttctccagaa gttacagatg gacctaagac agaagaagaa ctattagcac ttgaaaaaga
    18001 aaaaccggct gaagaaaaac caaaagagga taaacctgca gctgctaaaa ctgaaacacc
    18061 taagacggta acccctgaat ggcaaacggt agagaaaaaa gaacaacagg gaacagtcac
    18121 tatccgagaa gaaaaaggtg tccgctacaa ccaactatct tcaactgctc aaaatgataa
    18181 cgcaggtaaa ccagccctgt ttgaaaagaa gggcttgacc gttgatgcca atggaaatgc
    18241 aactgttgat ttaaccttca aagaagattc tgaaaagggc aaatcacgct ttggtgtctt
    18301 cctgaaattt aaagatacca agaacaatgt ttttgtcggt tatgacaagg atggttggtt
    18361 ctgggagtat aaatctccaa caactagcac ttggtataga ggtagtcgtg ttgctgctcc
    18421 tgaaacagga tcaacaaacc gtctctctat cactctcaag tcagacggtc agctaaatgc
    18481 cagcaataac gatgtcaatc tctttgacac agtgactcta ccagctgcgg tcaatgacca
    18541 tcttaaaaat gagaagaaga ttcttctcaa ggcgggctct tatgacgatg agcgaacagt
    18601 tgttagcgtt aaaacggata accaagaggg ggtaaaaaca gaggataccc ctgctgaaaa
    18661 agaaacaggt cctgaagttg atgatagcaa ggtgacttat gacacgattc agtctaaggt
    18721 cctcaaagca gtgattgacc aagccttccc tcgtgtcaag gaatacagct tgaatggaca
    18781 tactttgcca ggacaggtgc aacagttcaa ccaagtcttt atcaataacc accgaatcac
    18841 ccctgaagtc acttataaga aaatcaatga gacaacagca gagtacttga tgaagcttcg
    18901 cgatgatgct cacttaatca atgcggaaat gacagtacgc ttgcaagttg tggacaatca
    18961 attgcacttt gatgtgacca agattgtcaa ccacaatcaa gtcactccag gtcaaaagat
    19021 tgatgacgaa agaaaactac tttcttctat tagtttcctc ggcaatgctt tagtctctgt
    19081 ttctagtgat caaactggat ctaagtttga tggggcaacc atgtcaaaca atacgcatgt
    19141 cagcggagat gatcatatcg atgtaaccaa tccaatgaaa gacctagcca agggttacat
    19201 gtatggattt gtttctacag ataagcttgc tgctggtgtt tggagtaact ctcaaaatag
    19261 ctatggtggt ggttcgaatg actggactcg tttgacagct tataaagaaa cagtcggaaa
    19321 tgccaactat gtaggaatcc acagctctga atggcaatgg gaaaaagctt ataagggcat
    19381 tgttttccca gaatacacga aggaacttcc aagtgctaag gttgttatca ctgaagatgc
    19441 caatgcagac aagaaagttg attggcaaga tggtgccatt gcttatcgta gcattatgaa
    19501 caatcctcaa ggttgggaaa aagttaagga tatcacagct taccgtatcg cgatgaactt
    19561 tggttctcaa gcacaaaacc cattccttat gaccttggat ggtatcaaga aaatcaatct
    19621 ccatacagat ggtcttgggc aaggtgttct ccttaaagga tatggtagcg aaggccatga
    19681 ctctggtcac ttgaactatg ctgatattgg taagcgtatc ggtggtgtcg aagacttcaa
    19741 gaccctaatt gagaaggcta agaaatatgg agctcatcta ggtatccacg ttaacgcttc
    19801 agaaacttat cctgagtcta aatacttcaa tgaaaaaatt ctccgtaaga atccagatgg
    19861 aagctataac tatggttgga actggctaga tcaaggtatc aacattgatg ctgcctatga
    19921 cctagctcat ggtcgtttgg cacgttggga agatttgaag aaaaaacttg gtgacggtct
    19981 cgactttatc tatgtggacg tttggggtaa tggtcaatca ggtgataacg gtgcctgggc
    20041 tacccacgtt cttgctaaag aaattaacaa acaaggctgg cgctttgcga tcgagtgggg
    20101 ccatggtggt gagtacgact ctaccttcca tcactgggca gctgacttga cctacggtgg
    20161 ctacaccaat aaaggtatca acagtgccat cacccgcttt atccgtaacc accaaaaaga
    20221 tgcttgggtt ggggactaca gaagttatgg tggtgcagcc aactatccac tgctaggtgg
    20281 ctacagcatg aaagactttg aaggctggca aggaagaagt gactacaatg gctacgtgac
    20341 taacctcttt gctcatgacg tcatgactaa gtacttccaa cacttcactg taagtaaatg
    20401 ggaaaatggt acaccggtga ctatgaccga taacggtagc acctataaat ggactccaga
    20461 aatgcgagtg gaattggtag atactgacaa taataaagta gttgtaactc gtaagtcaaa
    20521 tgatgtcaat agcccacaat atcgcgaacg tacagtaacg ctcaacggac gtgtcatcca
    20581 agatggttca gcttacttga ctccttggaa ctgggatgca aatggtaaga aactttctac
    20641 tgataaggaa aagatgtact acttcaatac gcaggccggt gcaacaactt ggacccttcc
    20701 aagcgattgg gcaaagagca agatttacct ttacaagcta actgaccaag gtaagacaga
    20761 agagcaagaa ctaactgtaa aagatggtaa aattacccta gatcttctag caaatcaacc
    20821 atacgttctc tatcgttcaa aacaaaccaa tcctgaaatg tcatggagtg aaggcatgca
    20881 catctatgac caaggattta atagcggtac cttgaaacat tggaccattt caggcgatgc
    20941 ttctaaggca gaaattgtca agtctcaagg ggcaaacgat atgcttcgta ttcaaggaaa
    21001 caaagaaaaa gttagtctca ctcagaaatt aactggcttg aaaccaaata ccaagtatgc
    21061 cgtttatgtc ggtgtcgata accgtagtaa tgccaaggca agtatcactg tgaatactgg
    21121 tgaaaaagaa gtgactactt ataccaataa gtctctcgcc ctcaactatg taaaagccta
    21181 cgcccacaat acacgtcgtg acaatgctac agttgacgat acaagttact tccaaaacat
    21241 gtacgccttc tttacaactg gatcggacgt ctcaaatgta actctgacat tgagtcgtga
    21301 agctggtgaa caagcaactt actttgatga aattcgtacc tttgaaaaca attcaagcat
    21361 gtacggagac aagcatgata caggtaaagg caccttcaag caagactttg aaaatgtagc
    21421 tcagggtatc ttcccatttg tagtgggtgg tgtcgaagct gtcgaagaca accgtactca
    21481 cttgtctgaa aaacacgatc catatacaca acgtggttgg aatggtaaaa aagtcgatga
    21541 tgttatcgaa ggaaattggt cactcaagac aaatggacta gtgagccgtc gtaacttggt
    21601 ttaccaaact attccgcaaa acttccgttt tgaagcaggt aagacctacc gtgtaacctt
    21661 tgaatacgaa gcaggatcag acaataccta tgcttttgta gtcggtaagg gagaattcca
    21721 atcaggtcgt cgtggtactc aagcaagcaa cttggaaatg catgaattgc caaatacttg
    21781 gacagattct aagaaagcca agaaggtaac cttccttgtg acaggtgcag aaacagggga
    21841 tacttgggta ggtatctact caactggcaa tgcaagtaat actcgtagtg attctggtgg
    21901 aaatgccaac ttccgtggtt ataacgactt catgatggat aatcttcaaa tcgaagaaat
    21961 taccctaaca ggtaagatgt tgacagaaaa tgctctgaag aactacttgc caacggttgc
    22021 catgactaac tacaccaaag agtctatgga tgctttgaaa gaggcggtct ttaacctcag
    22081 tcaggccgat gatgatatca gtgtggaaga agcgcgtgca gagattgcca agattgaagc
    22141 cttgaagaat gctttggttc agaagaaaac ggctttggta gcagaagact ttgcaagtct
    22201 tacagctcct gctcaggctc aagaaggtct tgcaaatgcc tttgatggaa acttatctag
    22261 tttatggcat acatcatggg gcggaggaga tgtaggcaag cctgcaacca tggtcttgaa
    22321 agaagcaaca gaaatcactg gacttcgtta tgttccacgt ggatcaggtt caaatggtaa
    22381 cttgcgtgat gtgaaacttg ttgtgacaga tgagtctggc aaggagcata cctttactgc
    22441 aactgattgg ccagataaca ataagccaaa agacattgat tttggtaaga caattaaggc
    22501 taagaaaatt gtccttacag gtactaagac ttacggagat ggtggcgata aataccaatc
    22561 tgcagcggaa cttatcttta ctcgtccaca ggtagcagaa acacctcttg acttgtcagg
    22621 ctatgaagca gctttggcta aggctcagaa attaacagac aaagacaatc aagaggaagt
    22681 agctagcgtt caggcaagca tgaaatatgc gacggataac catctcttga cggaaagaat
    22741 ggtggaatac tttgcagatt atctcaacca attaaaagat tctgctacga aaccagatgc
    22801 tccaactgta gagaaacctg agtttaaact tagctcttta gtttccaatc aaggtaagac
    22861 gccagattat aagcaagaaa tagatagacc agaaacacct gaacaaatct tgccagcaac
    22921 aggtgagagt caatctgaca cagccctctt cctagcaagt gttagtctag ccctatctgc
    22981 tctctttgta gtaaaaacga agaaagacta gtatttagta aaacctctta acaagattac
    23041 ggaagcagtc tctatctttt ccaatgaggt ttatagtaca gaaaaagcct gagaagatgt
    23101 cttctcaggc ttttgttaag cacataaata caatagtgct atgacaaaat cacccagaaa
    23161 aatctgggtg ataaatgtta tggttgtgct ggttgaggat tctgattttg ttgatcaggg
    23221 gttgtatttg attgttgcgt attattgtta ggattggtag tcgtactatt atttgtgctt
    23281 ggagtggttg agctagactg tgaagttgaa ctatctgatg atgagcttga actttcagtt
    23341 gatgggggtt gttgtggagc aggtgagttc cacgtagaac gagcaccatt tttaaatacg
    23401 aattctccat ttctgtagag cccctctggt atattccaat cctctggatt gcttccttca
    23461 gacagatagg tcatcataga gcggtaaact ttggcagcga ccgtaaggcc attgcctaca
    23521 agtggtgtca gacggttaga atagcctgtc catacagcca ttgaatattt acgcgtatag
    23581 ccagcaaata gttcatcagg tgctacaaat tgagaggtct tgatgtggtt ttcaatttcc
    23641 tcgtctgtat agttagaggt tcctgtttta ccagcctgag ggagccaagc aagataggca
    23701 tttcgtccag ttccataact caagactgtt ttcatcatgt cggtcatcat ataggctgtc
    23761 gtttccttca tggcacgagt tccgacatta gagaactctt tttcactccc atcactaaag
    23821 acgactttat ggatatacat tggtttatag taagttccac catttgcaaa ggcagcgtaa
    23881 gcagcagcca tcttttcact acttgctcca tattttttgt ctgattcggt tgtgttactt
    23941 gaaatggcat ttgagtagtg aatacttggg tagtcgattc cgagaccatt taggaaagtc
    24001 ttggcgcggt tgagtccgac cttgtttaga gtttccacgg ctgggacgtt tcgcgattgt
    24061 tgcagggcgt attgcaaggt gatgttgcca aagtagcccc tatcccagtt ataaacaggg
    24121 gtatttgtcc cagggtagtt atagggctca tcgtgaacga tagtagcagt tgaatcgtag
    24181 ataccgtact ccaaggcagg agcatagtct gtgatcggtt tcatagttga tccccagtcg
    24241 cggtttgttt ctactgcttg gttaattccg aaggaaacat tacttgactg atggcgtgct
    24301 cctagctggg caatgacttt accgttagaa acatcaacaa tggtagaagc gacttgcaat
    24361 tcatcgtctg gataggcaac gtattcgtct gtattgtaaa tatcccacag atgtttttga
    24421 gcttcttggt ctacatttgt gtagacatcc atcccagttg tgagcaggtt atagcctgtt
    24481 tcttcttcaa cttgattgat gacttccttg aggtaattat ccatgtaagc agggtaatta
    24541 cttgctgatt tgagactttg tagtccatca gtaattggtg tattgactgc tttctcatac
    24601 tgttcagcag agatgtagcc ttgatttttc atttcagata agaccaagtt tcggcggtct
    24661 tgggctgctt ctggatgtga ataggggtca tattggtttg gtgcctgagg cattccagcc
    24721 agcaaggcta actgaggtaa acttaaatta ttgaggtctt taccatagta gttttgagct
    24781 gctgtctgca ttccatagtt cccattagac atgtagacct tatttatata gtaggtcaag
    24841 atttcttgct tggttgcttt ttgttctaac tgaatcgcta accaagcttc ctgagcctta
    24901 cgagaaatag tctggtcgga agtcgaagtt gaaaagtaag tcaacttaat caactgttga
    24961 gtgagagttg atccaccttg gagggaattg ctttgcagat tgcgcaagaa agctcccagg
    25021 atacggatgg tatcaatccc cctgtggtcg aagaagcgat ggtcttcgat agaaacgatt
    25081 gctttaacca aatctgtggg aatatcatta gcttgggcat tgacgcggcg ttcagaaccc
    25141 aagtcagcaa tgagttgatt tttattgtcg tagattttac tagaagttgt tgcaactagt
    25201 ttactctcgg ataggctagg agccttgcta acgtagtaga aaaaaactcc tccgcctaag
    25261 acaatggctg cgataaccaa gcttaagaag ctaatgctca gatacttgat taggcgcaga
    25321 atcgttggtt tgttcatctt gttttaccac ctaataaatg ttctttgata acattgagat
    25381 aaggaatttg agggaaggca ccagccttga tttcatatcc atattctcga atatattcaa
    25441 gtggcattga tttttgtccc ttatcttgat gatagaagcg aatcaaatcg aatgccggca
    25501 ataagtaggt ttcttgctga gaagaaaagt gaagaaggac aaagcagatt ccttgttggg
    25561 caaggacttg ttccatatgc tgaatctgat gtggatgaaa atttttcatc ggaatcgcac
    25621 gtttttgttt tgtttccttg acttcaaagt cgatgtaata tccattataa acgccagaat
    25681 agtccgtcgt tgaagcttgt cgaaaatagg cttcaacaat cttggcacga cttcgttgtg
    25741 gatagtccac ttgtacgatt tgaataggag ttggtttctt atgtataaca gccaagccct
    25801 gagacaaata gtagtcgttg gtagcattga tcatcttttc aaaagacatt cctcgatttg
    25861 cgaaattttt gggttgagaa agagatgttt gtcttttttg tgatgaaact ttatgtggat
    25921 agttgaccat aattctcctt attggtacaa taacatcact ttattatacc ataatttgca
    25981 cagaaagggt taaaaatggc tacagctttg gttttaggct attctgcttt tgatttgggt
    26041 ttattttctg ataaggatcc tcgtcttaaa ttgattaaaa aagcgatacg taaagattta
    26101 gaggctatgg cagcagatgg ggtgtcttgg cttgtgttta cagggacttt gggctttgaa
    26161 tattgggttt tagaggttgc tcaggagatg aaaaccgaat acggtttcca gttggccacc
    26221 atttttgctt ttgaaaccca tggggaaaat tggaatgaag gcaatcagat gaaactgagt
    26281 cgctttaagc aggtagactt tgtcaaatat gcctatcctc gctatgaaca caaggggcag
    26341 ttaagagatt accagcagtt tttgctggaa aacacgacta gttcctatct tttttatgat
    26401 gaagaaaatg aaacaaaact agcttatttt taccaaaaga tgaaaaatca agaggactat
    26461 tttataaaga gattaacatt tgatcaatta aatgaacttg ctgaaaattt ttccgaaaat
    26521 tgaagctttg accttgattt ttgtttgcct ttttttatat aataatacta gcaagcgaga
    26581 atggagagag acatggcaag tattattttt tcagcgaaag atatttttga acaggagttt
    26641 ggacgtgaag tccgtggcta taataaagta gaagttgacg agtttttaga cgatgtcatc
    26701 aaggactatg aaacctatgc tgccttggtc aagtcacttc gtcaggaaat tgcggatttg
    26761 aaggaagaat taactcgtaa accgaaacct tcaccagttc aagcagaacc ccttgaagcg
    26821 gcaattacaa gttctatgac gaattttgat attttgaaac gcctgaatag attggaaaaa
    26881 gaagtttttg gtaaacaaat tttagataac tcagattttt aagtagttat ttgagatgtg
    26941 caatttttgg ataatcgcgt gaggagaatt gcttctcatg aggaaagtcc atgctagcac
    27001 aggctgtgat gcctgtagtg tttgtgctag gcgaaaccat aagcctaggg acgagaaatc
    27061 gttacggcag ttgaaatggc taagtccttg gataggccag agtaggcttg aaagtgccac
    27121 agtgacgaag tctttctgga aacagagaga gtggaacgcg gtaaacccct caagctagca
    27181 acccaaattt tggtcggggc atggagtacg cggaaacgaa cgtagtattc tgactgctat
    27241 cagctagagc tgttagtggt agacagatga ttatcgaagg aagtggtcct agtcacttct
    27301 ggaacaaaac atggcttata gaaaattgca tataggttgg ggctgagaaa ttttctcaac
    27361 ctcatttttt aaagtggaca tatagaaagg tcttgcaaga ctgtaacatg aaaaaagaat
    27421 ttaatttaat tgcaactgcg gcagcagggc ttgaggctgt cgttggtcgt gaagtgcgag
    27481 agttgggcta cgattgtcag attgaaaatg gacgtgttcg ttttcaagga gacgtgagag
    27541 ctattatcga aaccaacctt tggctgcggg cagcagatcg tatcaaaatt atcgtaggaa
    27601 cgttccctgc taagactttt gaagagctat ttcagggagt tttcgcttta gattgggaaa
    27661 attatttacc acttggagct cggttcccga tttcaaaagc taaatgtgtt aagtccaaac
    27721 ttcacaatga gcccagtgtt caggctattt ctaagaaagc tgttgtcaag aaattgcaga
    27781 aacactatgc tcgcccagaa ggggttcctc tgatggagaa tggcccagag tttaagattg
    27841 aggtctctat tctcaaagat gtggcaactg tcatgattga tacgaccggg tctagcctct
    27901 ttaaacgtgg ttatcgtacc gaaaaaggtg gcgctcctat caaggaaaat atggcagcag
    27961 ccattttaca actttctaac tggtatccag acaagccttt gattgatccg acctgtggtt
    28021 cggggacttt ctgtattgag gcagttatga ttgctagaaa gatggcgcca ggtcttcgtc
    28081 gctcttttgc atttgaggaa tggaactgga tcagcgatcg cttgattcaa gaagtgcgca
    28141 cagaagcggc taaaaaagta gaccgtgagc ttgagctgga tatcatgggc tgtgatattg
    28201 atgctcgcat ggtggaaatt gctaaggcca atgctcaggc agctggtgtt gcaggagaca
    28261 ttacttttaa gcagatgcgc gtgcaggatt tacgttccga taaaatcaat ggagtaatca
    28321 tttccaatcc gccttatggt gaacgtttgt cagatgatgc aggggtgacc aagctctatg
    28381 ctgagatggg gcaagtattt gcaccgctga aaacttggag caaatttatc ctgactagtg
    28441 atgaagcttt tgaaagcaag tatggtagcc aagcagataa gaagcgtaag ttatacaacg
    28501 gaaccttgaa agtggatctg tatcaatatt ttggtcagcg tgtcaaacgg caagaggtaa
    28561 aatagaaagg gatactcatg agtaaaaaaa gacgaaatcg tcaaaaaaaa gaaggtcaag
    28621 aaccgcaatt tgattttgat gaagcaaaag agctaacagt tggtcaagct attcgtaaaa
    28681 atgaagaagt ggaagcagga gtcttgcctg aggattccat tttggacaag tatgttaagc
    28741 aacacagaga tgaaattgag gcggataagt ttgcgactcg tcaatacaaa aaagaggagt
    28801 tcgttgaaac tcagagtctg gatgatttaa ttcaagagat gcgtgaggct gtagagaagt
    28861 cagaagcttc ttcggaggaa gttccatctt ctgaagacat cttactaccc ttgcctctgg
    28921 acgatgagga gcaaggcttg gatcctctat tgctagatga tgaaaatcca acagaaatga
    28981 ctgaagaagt ggaagaggag caaaaccttt ctcgtctgga tcaagaggac tcagaaaaga
    29041 aaagtaaaaa aggctttatt ttgaccgttt tggcgcttgt atcagtaatt atttgtgtca
    29101 gtgcttatta tgtctaccgt caagtggctc gttcgaccaa ggaaattgaa acttctcaat
    29161 caactacagc caatcaatcg gatgtggatg attttaatac actttatgac gccttttaca
    29221 cagatagcaa taaaacggct ttgaaaaata gccagtttga taaactgaat caactcaaga
    29281 ctttacttga taagctggaa ggtagtcgtg aacatacgct tgccaaatct aaatatgata
    29341 gtctagcaac gcaaatcaag gctattcaag atgtcaatgc tcaatttgag aaaccagcta
    29401 ttgtggatgg tgtgttggat gccaatgcca aagccaaatc ggatgctaaa tttacggata
    29461 ttaaaactgg aaatacggag cttgataaag tgctagataa ggctatcagt cttggtaaga
    29521 gccagcaaac aagtacttct agctcaagtt caagtcaagc aagctcaaat acgacaagtg
    29581 agccaaaacc aagtagttca aatgagacta gaagtagtcg cagtgaagtc aatatgggtc
    29641 tctcgagtgc aggggttgct gttcaaagaa gtgccagtcg tgttgcctat aatcagtctg
    29701 ctattgatga tagtaataac tctgcctggg attttgcgga tggtgtctta gaacaaattc
    29761 tagcgacttc acgttcacgt ggctatatca ctggagacca atatatcctt gaacgtgtca
    29821 atatcgttaa cggcaatggt tattacaacc tctacaagcc agatggaacc tatctcttta
    29881 cccttaactg taagacaggc tactttgtcg gaaatggcgc tggtcatgcg gatgacttgg
    29941 actactaagc agtcgttaca aaattctttc ttttcaaaag taaaaatgat aaaataaaac
    30001 aaatgaaaca agaggagtgt caaatgacaa aagctaactt tggtgtcgta ggtatggccg
    30061 taatgggtcg taaccttgcc cttaatattg aatctcgtgg ttacacagtt gctatctaca
    30121 accgtagtaa agaaaaaacg gaagatgtga ttgcttgcca tcctgaaaaa aactttgtac
    30181 caagctatga cgttgaaagt tttgtaaact caatcgaaaa acctcgtcgt atcatgctga
    30241 tggttcaagc tggacctggt acagatgcta ctatccaagc ccttcttcca caccttaaca
    30301 agggggatat cttgattgac ggaggaaata ctttctacaa agataccatc cgtcgtaatg
    30361 aagaattggc aaactcaggt atcaacttta tcggtactgg ggtttctggt ggtgaaaaag
    30421 gtgcccttga aggtccttct atcatgcctg gtggacaaaa agaggcctac gaattggttt
    30481 cggatgttct tgaagaaatc tcagctaaag caccagaaga tggcaaacca tgtgtgactt
    30541 atatcggtcc tgatggagct ggtcactatg tgaaaatggt tcacaacggt atcgagtacg
    30601 gtgatatgca attgatcgca gaaagttatg acttgatgca acacttgcta ggtctttctg
    30661 cagaggatat ggctgaaatc tttactgagt ggaacaaggg tgaattggat agctacttga
    30721 tcgaaatcac agctgatatc ttgagccgta aagacgatga aggccaagat ggaccaatcg
    30781 tagactacat ccttgatgct gcaggtaaca agggaactgg taaatggact agccaatcat
    30841 ctcttgacct tggtgtacca ttgtcactga ttactgagtc agtgtttgca cgctacattt
    30901 caacttacaa agaagaacgt gtatatgcta gcaaggtgct tccaaaacca gctgccttca
    30961 actttgaagg agacaaggct gaattgattg aaaagatccg tcaagccctt tacttctcaa
    31021 aaatcatttc atacgcacaa ggatttgctc aattgcgtgt agcctctaaa gaaaacaact
    31081 ggaacttgcc atttgcagat atcgcatcta tctggcgtga tggctgtatc atccgttctc
    31141 gttttttgca aaagattaca gatgcttaca accgcgatgc agatcttgcc aaccttcttt
    31201 tggacgagta cttcttggat gttactgcta agtatcaaca agcagtgcgt gatatcgtag
    31261 ctcttgcggt tcaagctggt gtgccagtgc caactttctc agcagctatt acttactttg
    31321 atagctaccg ttcagctgac cttccagcta acttgatcca agcacaacgt gactactttg
    31381 gtgctcacac ttaccaacgt aaagacaaag aaggaacctt ccactactct tggtatgacg
    31441 aaaaataagt aggtcagcca tggggaaacg gattttatta cttgagaaag aacgaaatct
    31501 agctcgtttt ttaagtttgg aactccagaa agagcagtat cgggttgatc tggtagagga
    31561 ggggcaaaaa gccctctcca tggctcttca gacagactat gatttgatgt tattgaacgt
    31621 taatctggga gatatgatgg ctcaggattt tgcagaaaaa ttgagtcgaa ctaaacctgc
    31681 ctcagtcatc atgattttag atcattggga agacttgcaa gaagagctgg aagttgttca
    31741 gcgttttgca gtttcataca tttataagcc agtccttatc gaaaatctgg tagcgcgtat
    31801 ttcggcgatc ttccgaggtc gggacttcat tgatcaacac tgcagtctga tgaaagttcc
    31861 aaggacctac cgcaatctta ggatagatgt tgaacatcac acggtttatc gtggtgaaga
    31921 gatgattgct ctgacccgcc gtgagtatga ccttttggcg acacttatgg gaagcaagaa
    31981 agtattgact cgtgagcaat tgttggaaag tgtttggaag tatgaaagtg cgaccgagac
    32041 aaatatcgta gatgtctata tccgctatct acggagcaag cttgatgtta aaggccaaaa
    32101 aagctacatt aaaaccgtgc gtggtgttgg atataccatg caagaataga taagcagttg
    32161 cagttgtgta actgcttttt tgaggagttt ttatatattg acatgcagtc gggtctttgc
    32221 tacaatcgtt ttaggaggat atatagatga aacttttgaa aaaaatgatg caagttctac
    32281 tagcagtctt tttctttggt ttgctagcta caaatacggt atttgcgaat accacaggtg
    32341 gccgatttgt tgataaggat aatagaaaat attatgtaaa agatgatcat aaagcaatct
    32401 attggcataa aatagacggt aaaacttact attttggtga tattggagag atggttgtcg
    32461 gttggcaata cttagaaatt cctggaacag gttatcgtga taatttattc gataaccaac
    32521 cagttaatga gattggcctt caggagaagt ggtactattt tggacaagat ggtgctttgc
    32581 tagaacaaac agataaacaa gtactagagg caaaaacgtc tgaaaataca ggaaaagtat
    32641 acggtgaaca atatcctcta tctgctgaaa agagaactta ttattttgat aataattatg
    32701 ctgtaaagac aggctggatt tatgaagacg gcaattggta ttatttaaat aagctaggaa
    32761 attttggcga tgattcttac aatccactac caattggtga agttgctaag ggttggactc
    32821 aagattttca tgttactatt gacattgata gaagcaaacc tgctccatgg tactacctag
    32881 acccagaaac tggcattatg cgaacaggat ggcaatatct aggtaataac tggtactacc
    32941 tccgttcatc aggagcaatg gcaactggct ggtatcagga aggctcaact tggtactacc
    33001 taaatgcagg taatggagac atgaagacag gttggttcca ggtcaatggc aaatggtact
    33061 atgcttatag ctcaggtgct ttggcggtga atacgaccgt agatggctac tacgtcaact
    33121 ataatggcga atgggttcgg taatgacagg gcgcttataa ttatattaga acactcgctt
    33181 aatcaaagaa gtgactttgt tgtacttgac ctgacgattg gggagattaa aagcatgtga
    33241 aatctacaca tgctttttcg ttagttatga gtgttgaact tgactaacca ttgacaaaag
    33301 ataagagcaa tcaaaataag atacaaaaat atcaatgcta actgcaccga aacgcccgat
    33361 gctatggaca gggctaatag ggagagcagg gacggggcga gaatgtctac tgtgctcaga
    33421 gcagagccca ccgtccccat cttgtcactg gggatatggg caaagacagc tgcttgtagg
    33481 cgagggctga gaatgccgat aatcgtagaa ctgatgaaac tggtcatgaa aattacgata
    33541 taggcttgac aaaggatact agttattaga gccaataggg aaatctcaca gaaaaccaag
    33601 aggtgcgtga aacggatatt tttaaataga ttactgctgg tcatattgcc aaggatagct
    33661 ccacaagaaa tgatgatgga gagcatggcg aggagttgcc caatgctcag ttgtgctagt
    33721 gtctgttgga tgaagcggag ggcaatcagc cgaggggaca catccaagat ggcaatcata
    33781 ctggtcgtca gaaacagtag tatgacggta tcttttaacc tcaggagcac agccagcgac
    33841 tgtttaagat gttgaaaata tttcttaaaa ctcagtgctg tatgtgacat ttcaatcctt
    33901 ttttcaacct catacaaggt atgtctaata acatacagac ccaaaaaggc aatgacaaaa
    33961 gtcagagtgt tgataaggga aatagtttga atactcataa cattgataag gaatgcgcca
    34021 gccagattgg cgacaatgtg gacaaccctc atcagagact gcctgaaccc catggcatca
    34081 tgcaggtcgt ccttaattac actgatgtag agggcgttca tcatgtaggc agacaggtag
    34141 ctcaaggtgt cagagatgag gttgatgatg acaatcataa tgactgaaac taatgaaaag
    34201 ggcgacaaga cgagaaatac tgtcaaaata gcgtagagca ggattttgat tttggcaatc
    34261 cagagtgcgt gtttgactct attttcttga aaatctccta gaatcccgag aaagagttgc
    34321 gatagtaggg gaaccatctc tgaaatggaa atcagtaaaa tcgctagcgg agcgaaattg
    34381 tactgagcca cataattgat aatggcgagg tagaaaatac tgtcgccgaa tgatgaaaaa
    34441 cagctgttta gcagcaactg tctatatatg ttgtttgtcc aaaataattt catacttttc
    34501 tccttatgtc tgcacatcga atgggaattt attatttaat agacaccaat ataccccatg
    34561 cttcctattc cgaagtcaaa caaatctgtt ttaccactat ctccttgaaa catcagtaaa
    34621 ccgtgatcat ctcgttcaga acatgctaaa attacctgtt ggattttttc atcagtaatt
    34681 tgttttgatt gtagacagtg gtttgtagta agctagttat tccgtggcaa tatcctgtca
    34741 tcatttttag atgatggtta aaaacaaatt cttgatattt actaataata tctttgtttc
    34801 cgtcacaatc gtacatacaa agatataaga ttattccgga aattccttcg caccaagaaa
    34861 gttgtaaatt tcctaaattt tcagtattag aagtaacttt ttctaataat ttttttaatt
    34921 cagcatggaa tgtatggaga tcattataga acatagaagg ttctaagact ttagaatagg
    34981 caaataaagc atatgcaatt tcacaatatc catgagcaaa gctatagtct aaaatgcttt
    35041 ctttggctgt atctctttgt aggaaataat gataaatttc cccatatact attgtggatg
    35101 aaagttttaa gagtattgtc attggtaaat tgatagtatt ttattaatga taataggaca
    35161 ccagattttc ccaatgcaaa gtctatttcc tctagagtat cataattctc tattaatttc
    35221 ttagcggtga cgtttgctaa ttgtagatag tattgatttt tactgataga aaataaatgt
    35281 aggagtaacc atagatagcc tgcatcacca aatagcagtg agtattgata ttcatatgtg
    35341 tgtgtcgttc taattgtcac tgccttcttg atgatagaga gtattttaga atccagttct
    35401 ggggggtaca atttatttag aggaaacagt agtccagcta ttccgtgttg gaatgataaa
    35461 ttacttacga aatttccaaa ttctgttgaa gaagtgatcc ttccttcaga atttacagtt
    35521 ttatctagta aaaatcgtag aacactatta cattctgttt tgtaatcata tttatgttcc
    35581 tctatttttt taattttgac taaattattt gtttgactta aatttagtag acattgtaac
    35641 caaaatagtt gctcatctgt gagctgacct tgagtatgtg atagttctag taattgaata
    35701 ggatccttta gttagattca atcaatctat aacacaacaa c
//
LOCUS       DBEJHE010000021        34123 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC4 isolate 671759
            SAMN38261586-rid24793303.denovo.21, whole genome shotgun sequence.
ACCESSION   DBEJHE010000021 DBEJHE010000000
VERSION     DBEJHE010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261586
            Sequence Read Archive: SRR26833752
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 34123)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34123)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576136.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576136.1
            Genome Coverage       :: 109x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 19:48:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,067
            CDSs (total)                      :: 2,029
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 131
            CDSs (without protein)            :: 131
            Pseudo Genes (ambiguous residues) :: 0 of 131
            Pseudo Genes (frameshifted)       :: 64 of 131
            Pseudo Genes (incomplete)         :: 59 of 131
            Pseudo Genes (internal stop)      :: 46 of 131
            Pseudo Genes (multiple problems)  :: 32 of 131
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34123
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261586-rid24793303.denovo.21"
                     /strain="GPSC4"
                     /isolate="671759"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(422..1111)
                     /gene="rplA"
                     /locus_tag="ACL3EZ_001357"
     CDS             complement(422..1111)
                     /gene="rplA"
                     /locus_tag="ACL3EZ_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HGR0392919.1"
                     /translation="MAKKSKQLRAALEKIDSTKAYSVEEAVALAKETNFAKFDATVEV
                     AYNLNIDVKKADQQIRGAMVLPNGTGKTSRVLVFARGAKAEEAKAAGADFVGEDDLVA
                     KINDGWLDFDVVIATPDMMALVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGK
                     ITYRADRAGNVQAIIGKVSFEAEKLVENFKAFNETIQKVKPATAKGTYVTNLTITTTQ
                     GVGIKVDVNSL"
     gene            complement(1319..1744)
                     /gene="rplK"
                     /locus_tag="ACL3EZ_001358"
     CDS             complement(1319..1744)
                     /gene="rplK"
                     /locus_tag="ACL3EZ_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004226069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HGR0392920.1"
                     /translation="MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGMIIPVVISVYEDKSFTFVTKTPPAAVLLKKAAGVEKGSGTPNKTKVATVTR
                     AQVQEIAETKMPDLNAANVESAMRMIEGTARSMGFTVVD"
     gene            complement(1867..2583)
                     /gene="ldcB"
                     /locus_tag="ACL3EZ_001359"
     CDS             complement(1867..2583)
                     /gene="ldcB"
                     /locus_tag="ACL3EZ_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase LdcB/DacB"
                     /protein_id="HGR0392921.1"
                     /translation="MKKRYVILSGLLALTLAACSQEKTKVEENTQKTEQSSQPEGTVG
                     SKSQASSQKKAEVSNKGSYYSIQGKYDEIILANKRYPLSKDYNPGENPTAKAELLKLI
                     AAMQAEGYPISDQYSGFRSYETQAKLYQDYVNQDGKEAADRYSARPGYSEHQTGLAFD
                     LIGTDGDLVTEEKAAQWLLDHAADYGFVVRYLKGKEKETGYMAEEWHLRYVGKEAKEI
                     AASGLSLEEYYGFEGGDYVD"
     gene            complement(2601..3062)
                     /locus_tag="ACL3EZ_001360"
     CDS             complement(2601..3062)
                     /locus_tag="ACL3EZ_001360"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000335612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HGR0392922.1"
                     /translation="MCLICQRIELIKAGQNPYFVKELETGYVVIGDYQYFKGYTLFLA
                     KDHVTELHHMETSVKLRFLEEMSLVQEAVAKAFEAEKMNIELLGNGDAHAHWHLFPRR
                     AGDMKSHGLNGRGPVWWVPWEEMAAEDCQVQSPELEEMIKILSHELEKYLA"
     gene            complement(3064..4101)
                     /locus_tag="ACL3EZ_001361"
     CDS             complement(3064..4101)
                     /locus_tag="ACL3EZ_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HGR0392923.1"
                     /translation="MNQTVEYIKELTAIASPTGFTREISNYLVKTLEGFGYQPVRTAK
                     GGVNVTIKGQNDEQHRYVTAHVDTLGAIVRAVKPDGRLKLDRIGGFPWNMIEGENCTV
                     HVASTGQKVSGTILIHQTSCHVYKDAGTAERTQDNMEVRLDVKVSNEKETRALGIEVG
                     DFISFDTRTVVTDTGFIKSRHLDDKVSAAILLNLLRIYKKEKIELPVTTHFAFSVFEE
                     VGHGANSNIPAQVVEYLAVDMGAMGDDQQTDEYTVSICVKDASGPYHYDFRQHLVALA
                     KEQDIPFKLDIYPFYGSDASAAMSAGAEVKHALLGAGIESSHSYERTHIDSVIATERM
                     VDAYLKSEAVS"
     gene            complement(4199..5524)
                     /gene="brnQ"
                     /locus_tag="ACL3EZ_001362"
     CDS             complement(4199..5524)
                     /gene="brnQ"
                     /locus_tag="ACL3EZ_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015658 - branched-chain amino acid
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015803 - branched-chain amino acid
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HGR0392924.1"
                     /translation="MAKKGTLTGLLLFGIFFGAGNLIFPPSLGALSGEHFLPAIAGFV
                     FSGVGIAVLTLIIGTLNPKGYIYEISTKIAPWFATLYLSVLYLSIGPFFATPRTATTA
                     YEVGISPLLSDANKGLGLIVFTVLYFAAAYLISLNPSKILDRIGRVLTPVFAILIVIL
                     VVLGAIKYGGTSPQAASAAYQASAFGTGFLEGYNTLDALASVAFSVIAVQTLKQLGFS
                     SKKEYISTIWVVGIVVALAFSALYIGLGFLGNHFPVPAEAMKGGTPGVYILSQATQEI
                     FGSTAQLFLAAMVTVTCFTTTVGLIVSTAEFFNERFPQISYKVYATAFTLIGFAIANL
                     GLDAIIKYSIPVLVILYPITIAIVMIVIVNKFVALSKPGMQLTIAVVTVIAIASVLGS
                     SFKVEFLANLVSVLPFAKASLPWLVPAIVGILLSLVLPNKQESDVFEME"
     gene            complement(5695..5982)
                     /locus_tag="ACL3EZ_001363"
                     /pseudo
     CDS             complement(5695..5982)
                     /locus_tag="ACL3EZ_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658232.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
     gene            complement(6142..6720)
                     /locus_tag="ACL3EZ_001364"
     CDS             complement(6142..6720)
                     /locus_tag="ACL3EZ_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HGR0392925.1"
                     /translation="MSQIERIKQAIMADSQNASYTERGIEPLFAAPKTARINIIGQAP
                     GLKTQEAGLYWKDKSGDRLRDWLGVDEDTFYNSGYFAVLPMDFYFPGHGKSGDLPPRT
                     GFAEKWHPQLLQELPDIQLTLLIGQYAQAYYLQEKISGKVTERVKHYKDYLPAYFPLV
                     HPSPRNQIWMAKNPWFEAEVVPDLKKRIKTIL"
     gene            complement(6774..8174)
                     /gene="pepV"
                     /locus_tag="ACL3EZ_001365"
     CDS             complement(6774..8174)
                     /gene="pepV"
                     /locus_tag="ACL3EZ_001365"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004151 - dihydroorotase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HGR0392926.1"
                     /translation="MTAIDFTAEVEKRKEDLLADLFSLLEINSERDDSKADAQHPFGP
                     GPVKALEKFLEIADRDGYPTKNVDNYAGHFEFGDGEEVLGIFAHMDVVPAGSGWDTDP
                     YTPTIKDGRLYARGASDDKGPTTACYYGLKIIKELGLPTSKKVRFIVGTDEESGWADM
                     DYYFEHVGLAKPDFGFSPDAEFPIINGEKGNITEYLHFAGENTGVARLHSFTGGLREN
                     MVPESATAVVSGDLADLQAKLDAFVAEHKLRGELQEEAGKYKVTIIGKSAHGAMPASG
                     VNGATYLALFLSQFGFAGPAKDYLDIAGKILLNDHEGENLKIAHVDEKMGALSMNAGV
                     FRFDETSADNTIALNIRYPKGTSPEQIKSILENLPVVSVSLSEHGHTPHYVPMEDPLV
                     QTLLNIYEKQTGFKGHEQVIGGGTFGRLLERGVAYGAMFPDSIDTMHQANEFIALDDL
                     FRAAAIYAEAIYELIK"
     gene            complement(8187..8792)
                     /locus_tag="ACL3EZ_001366"
     CDS             complement(8187..8792)
                     /locus_tag="ACL3EZ_001366"
                     /EC_number="1.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002924506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0016657 - obsolete oxidoreductase
                     activity, acting on NAD(P)H, nitrogenous group as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HGR0392927.1"
                     /translation="MKFLELNKKRHATKHFTDKPVDPKDVRTAIEIATLAPSAHNSQP
                     WKFVVVREKNAELAKLAYGSNFEQVSSAPVTIALFTDTDLAKRARKIARVGGANNFSE
                     EQLQYFMKNLPAEFARYNEQQVSDYLALNAGLVAMNLVLALTDQGIGSNIILGFDKSK
                     VNEVLEIEDRFRPELLITVGYTDEKLEPSYRLPVDEIIEKR"
     gene            8963..9763
                     /locus_tag="ACL3EZ_001367"
     CDS             8963..9763
                     /locus_tag="ACL3EZ_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HGR0392928.1"
                     /translation="MKKFSLLLAILPFLVACGNQATPKETSAQKTIVLATAGDVPPFD
                     YEDKGNLTGFDIEVLKAVDEKLSDYEIQFQRTAWESIFPGLDSGHYQAAANNLSYTKE
                     RAEKYLYSLPISNNPLVLVSNKKNPLTSLDQIAGKTTQEDTGTSNAQFINNWNQKHTD
                     NPATINFSGEDIGKRILDLANGEFDFLVFDKVSVQKIIKDRGLDLSVVDLPSADSPSN
                     YIIFSSDQKEFKEQFDKALKELYQDGTLEKLSNTYLGGSYLPDQSQLQ"
     gene            complement(9947..10780)
                     /locus_tag="ACL3EZ_001368"
                     /pseudo
     CDS             complement(9947..10780)
                     /locus_tag="ACL3EZ_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001015777.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
     gene            complement(10770..12617)
                     /gene="uvrC"
                     /locus_tag="ACL3EZ_001369"
     CDS             complement(10770..12617)
                     /gene="uvrC"
                     /locus_tag="ACL3EZ_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009380 - excinuclease repair complex
                     [Evidence IEA];
                     GO_function: GO:0009381 - excinuclease ABC activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HGR0392929.1"
                     /translation="MNNLIKSKLELLPTSPGCYIHKDKNGTIIYVGKAKNLRNRVRSY
                     FRGSHDTKTEALVSEIVDFEFIVTESNIEALLLEINLIKENKPKYNIMLKDDKSYPFI
                     KITNERYPRLIITRQVKKDGGLYFGPYPDVGAANEIKRLLDRIFPFRKCTNPPSKVCF
                     YYHIGQCMAHTICKKDEIYFKSMAQEVSDFLKGQDNKIIDELKGKMAAAAQTMEFERA
                     AEYRDLIQAIGTLRTKQRVMAKDLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERDVNL
                     FPYFNDPDEDFLTYVGQFYQEKSHLVPNEVLIPQDIDEEAVKALVDSKILKPQRGEKK
                     QLVNLAIKNARVSLEQKFNLLEKSVEKTQGAIENLGRLLQIPTPVRIESFDNSNIMGT
                     SPVSAMVVFVNGKPSKKDYRKYKIKTVVGPDDYASMREVIRRRYGRVQREALTPPDLI
                     VIDGGQGQVNIAKQVIQEELGLDIPIAGLQKNDKHQTHELLFGDPLEVVDLSRNSQEF
                     FLLQRIQDEVHRFAITFHRQLRSKNSFSSQLDGIDGLGPKRKQNLMRHFKSLTKIKEA
                     SVDEIVEVGVPRAVAEAVQTKLNPQETEILLQVAEERVDYQTEGNHNKP"
     gene            complement(12657..13358)
                     /locus_tag="ACL3EZ_001370"
     CDS             complement(12657..13358)
                     /locus_tag="ACL3EZ_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M57 family metalloprotease"
                     /protein_id="HGR0392930.1"
                     /translation="MRWLFRLIGAFFSFVWRLFWRLVWIVVLLCVLAFGLLWYLNGDF
                     QGALKQAERSVKIGQQSIDQWEKTGQLPKLSQTDSHQHSEGRWAQASARIYLDPQMDS
                     RFQEAYLEAIQNWNQTGAFNFELVTESSKADITATEMNDGGTPVAGEAESQTNLLTGQ
                     FLSVTVRLNHYYLSNPYYGYSYERLVHTAEHELGHAIGLDHTDEKSVMQPAGSFYGIQ
                     EEDVANLRKIYETSE"
     gene            complement(13437..14669)
                     /gene="murN"
                     /locus_tag="ACL3EZ_001371"
     CDS             complement(13437..14669)
                     /gene="murN"
                     /locus_tag="ACL3EZ_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurN"
                     /protein_id="HGR0392931.1"
                     /translation="MALTTLTKEEFQTYSDQVSSRSFMQSVQMGDLLEKRGARIVYLA
                     LKQEGEIQVAALVYSLPMLGGLHMELNSGPIYTQQDALPVFYAELKEYAKQNGVLELL
                     VKPYETYQTFDSQGNPIDAEKKSIIQGLTDLGYQFDGLTTGYPGGEPDWLYYKDLTEL
                     TEKSLLKSFSKKGKPLVKKAETFGIRLKKLKREELSIFKNITKETSERREYSDKSLEY
                     YEHFYDTFGEQAEFLIASLNFSDYMSKLQGEQSKLEENLDKLRLDLSKNPHSEKKQNQ
                     LREYSSQFETFEVRKAEARDLIEKYGEEDIVLAGSLFVYMPQETTYLFSGSYTEFNKF
                     YAPALLQKYVMLESIKRGIPKYNFLGIQGIFDGSDGVLRFKQNFNGYIVRKAGTFRYH
                     PSPLKYKAIQLLKKIVGR"
     gene            complement(14674..15894)
                     /gene="murM"
                     /locus_tag="ACL3EZ_001372"
     CDS             complement(14674..15894)
                     /gene="murM"
                     /locus_tag="ACL3EZ_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurM"
                     /protein_id="HGR0392932.1"
                     /translation="MYRYQIGIPTLEYDQFVKEHELANVLQSSAWEEVKSNWQHEKFG
                     VYREEKLLATASILIRTLPLGYKMFYIPRGPILDYGDKELLNFAIQSIKSYARSKRAV
                     FVTFDPSICLSQSLINQEKTEFPENLAIIDSLQQMGVRWSGKTEEMGDTIQPRIQAKI
                     YKENFEEDKLSKSTKQAIRTARNKGLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEA
                     YYKKLLDNFKDKAYITLATLDVSKRSQELEEQLAKNRALEETFTESTRTSKVEAQKKE
                     KERLLEELTFLQEYIDVGQARVPLAATLSLEFGTTSVNIYAGMDDDFKRYNAPILTWY
                     ETARYAFERGMVWQNLGGVENSLNGGLYHFKEKFNPTIEEYLGEFTMPTHPLYPLLRL
                     ALDFRKTLRKKHRK"
     gene            complement(16006..16785)
                     /locus_tag="ACL3EZ_001373"
     CDS             complement(16006..16785)
                     /locus_tag="ACL3EZ_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HGR0392933.1"
                     /translation="MAVMKIEYYSQVLDMEWGVNVLYPDANRVEEPECEDIPVLYLLH
                     GMSGNHNSWLKRTNVERLLRGTNLIVVMPNTSNGWYTDTQYGFDYYMALAEELPQVLK
                     RFFPNMTSKREKTFIAGLSMGGYGCFKLALTTNRFSHAASFSGALSFQNFSPESQNLG
                     SPAYWRGVFGEIRDWTTSPYSLESLAKKSDKKTKLWAWCGEQDFLYEANNLAVKNLKK
                     LGFDVTYSHSAGTHEWYYWEKQLEVFLTTLPIDFKLEERLT"
     gene            complement(16854..18515)
                     /locus_tag="ACL3EZ_001374"
     CDS             complement(16854..18515)
                     /locus_tag="ACL3EZ_001374"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HGR0392934.1"
                     /translation="MSNISLTTLGGVRENGKNMYIAEIGESIFVLNVGLKYPENEQLG
                     VDVVIPNMDYLFENSDRIAGVFLTHGHADAIGALPYLLAEAKVPVFGSELTIELAKLF
                     VKGNDAVKKFNDFHVIDENTEIDFGGTVVSFFPTTYSVPESLGIVLKTSEGSIVYTGD
                     FKFDQTASESYATDFARLAEIGRDGVLALLSDSANADSNIQVASESEVRDEITQTIAD
                     WEGRIIVAAVSSNLSRIQQIFDAADKTGRRIVLTGFDIENIVRTAIRLKKLSLANEIL
                     LIKPKDMSRFEDHELIILETGRMGEPINGLRKMSIGRHRYVEIKDGDLVYIATAPSIA
                     KEAFVARVENMIYQAGGVVKLITQSLHVSGHGNVRDLQLMINLLQPKYLFPVQGEYRE
                     LDAHAKAAMAVGMLPERIFIPKKGTTMAYENGDFVPAGSVSAGDILIDGNAIGDVGNV
                     VLRDRKVLSEDGIFIVAITVNRREKKIVARARVHTRGFVYLKKSRDILRESSELINQT
                     VEEYLQGDDFDWADLKGKVRDNLTKYLFDQTKRRPAILPVVMEAK"
     gene            complement(18690..20912)
                     /gene="recJ"
                     /locus_tag="ACL3EZ_001375"
     CDS             complement(18690..20912)
                     /gene="recJ"
                     /locus_tag="ACL3EZ_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001832038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008409 - 5'-3' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HGR0392935.1"
                     /translation="MITPTYEWQFALQVENADFTKIAKKAGLGPEVARLLFERGIQDQ
                     ESLKKFLEPSLEDLHDAYLLHDMDKAVERIRQAIEEGENILVYGDYDADGMTSASIVK
                     ESLEQLGAECRVYLPNRFTDGYGPNASVYKYFIEQEGISLIVTVDNGVAGHEAIALAQ
                     SMGVDVIVTDHHSIPETLPDAYAIVHPEHPDADYPFKYLAGCGVAFKLACALLEEVQV
                     ELLDLVAIGTIADMVSLTDENRILVQYGLEMLGHTQRIGLQEMLDMAGIAANEVTEET
                     VGFQIAPRLNALGRLDDPNPAIDLLTGFDDEEAHEIALMIHQKNEERKEIVQSIYEEA
                     KTMVDPEKKVQVLAKEGWNPGVLGIVAGRLLEELGQTVIVLNIEDGRAKGSARSVEAV
                     DIFEALDPYRDLFIAFGGHAGAAGMTLEVEQLSDLSQILEDYVREKGADAGGKNKLNL
                     DEELDLEALSLETVKSFERLAPFGMDNQKPIFYIKNFQVESARTMGAGNAHLKLKISK
                     GEVSFEVVAFGQGRWATEFSQTKNLELAVKLSVNQWNGQTALQLMMMDARVEGVQLFN
                     IRGKNAVLPEGVPVLDFPGELPNLAASEAVVVKNIPEDITQLKTIFQEQHFSAVYFKN
                     DIDKAYYLTGYGTRDQFAKLYKTIYQFPEFDIRYKLKDLAAYLNIQQILLVKMIQVFE
                     ELGFVTIKDGVMTVNKEAPKREIGESQIYQNLKQTVKDQEMMALGTVQEIYDFLMEKE
                     "
     gene            21189..21948
                     /locus_tag="ACL3EZ_001376"
                     /pseudo
     CDS             21189..21948
                     /locus_tag="ACL3EZ_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398007.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
     gene            21988..22752
                     /locus_tag="ACL3EZ_001377"
     CDS             21988..22752
                     /locus_tag="ACL3EZ_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HGR0392936.1"
                     /translation="MISLFGLVAAKPVQANTSIADIQKRGELVVGVKQDVPNFGYKDP
                     KTGTYSGIETDLAKMVADELKVKIRYVPVTAQTRGPLLDNEQVDMDIATFTITDERKK
                     LYNFTSPYYTDASGFLVNKSAKIKKIEDLNGKTIGVAQGSITQRLITELGKKKGLTFK
                     FVELGSYPELITSLHAHRIDAFSVDRSILSGYTSKRTELLDDSFKPSDYGIVTKKSNT
                     ELNDYLDNLVTKWSKDGSLQKLYDRYKLKPSSHTAD"
     gene            22765..23442
                     /locus_tag="ACL3EZ_001378"
     CDS             22765..23442
                     /locus_tag="ACL3EZ_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HGR0392937.1"
                     /translation="MTDLSSWTAYFQDFGQFFNGFLFTLALAIGSFILAMVLGIFFGA
                     MSTSKRPILRILARIFVEFYQNTPLLVQFVIVFYGLPLISDHIIMIPIYWTAVLCVGL
                     YHGAYIAEVIRSGIQSIPSGQMEAALSQGFTYISAMRLITLPQAFCIILPPLTNQIVN
                     LIKNTSTVAIISGVDLMFVTKSWSALNGNYIPAFLGAALLYFALCFPVAQFGRKMEQA
                     NKKAYSL"
     gene            23452..24111
                     /locus_tag="ACL3EZ_001379"
     CDS             23452..24111
                     /locus_tag="ACL3EZ_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HGR0392938.1"
                     /translation="MESILEVLTPDNLVFIFKGFGLTLYISLIAIILSTIIGTVLAVM
                     RNGKNPILRIISSIYIEFVRNVPNLLWIFTIFLVFKIKSTPAGITAFTLFTSAALAEI
                     IRGGLNAVDKGQYEAGMSQGFTSAQILYYIILPQAIRKMLPAIISQFVPVIKDTSLLY
                     SVIALQELFGASQILMGRYFEPEQVFSLYILIALIYFSFNLAISSLSHMLAKRWQQAA
                     E"
     gene            24407..25597
                     /locus_tag="ACL3EZ_001380"
     CDS             24407..25597
                     /locus_tag="ACL3EZ_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferric reductase-like transmembrane
                     domain-containing protein"
                     /protein_id="HGR0392939.1"
                     /translation="MKSIKGLLFIIASFILTLLTWMNTSPQFMIPGLALTSLSLTFIL
                     ATRLPLLESWFHGLEKVYTVHKFTAFLSIILLIFHNFSMGGLWGSRLAAQFGNLAIYI
                     FASIILVAYLGKYIQYEAWRWIHRLVYLAYILGLFHIYMIMGNRLLTFNLLSFLVGSY
                     ALLGLLAGFYIIFLYQKISFPYLGKITHLKRLNHDTREIQIHLSRPFNYQSGQFAFLK
                     IFQEGFESAPHPFSISGGHGQTLYFTVKNSGDHTKNIYDNLQAGSKVTLDRAYGHMII
                     EEGRENQVWIAGGIGITPFISYIREHPILDKRVHFYYSFRGEENAVYLDLLRDYAQKN
                     PNFELHLIDSTKDGYLNFEQKEVPEHATVYMCSPISMMKALAKQIKKQNPKTELIYEG
                     FKFK"
     gene            complement(25918..26799)
                     /locus_tag="ACL3EZ_001381"
     CDS             complement(25918..26799)
                     /locus_tag="ACL3EZ_001381"
                     /EC_number="4.1.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004332 - fructose-bisphosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase"
                     /protein_id="HGR0392940.1"
                     /translation="MAIVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKKAP
                     VLIQTSMGAAKYMGGYKVARNLIANLVESMGITVPVAIHLDHGHYEDALECIEVGYTS
                     IMFDGSHLPVEENLKLAKEVVEKAHAKGISVEAEVGTIGGEEDGIIGKGELAPIEDAK
                     AMVETGIDFLAAGIGNIHGPYPVNWEGLDLDHLQKLTEALPGFPIVLHGGSGIPDEQI
                     QAAIKLGVAKVNVNTECQIAFANATRKFARDYEANEAEYDKKKLFDPRKFLADGVKAI
                     QASVEERIDVFGSEGKA"
     gene            complement(26940..28268)
                     /gene="vncS"
                     /locus_tag="ACL3EZ_001382"
     CDS             complement(26940..28268)
                     /gene="vncS"
                     /locus_tag="ACL3EZ_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase VncS"
                     /protein_id="HGR0392941.1"
                     /translation="MKRTGLFAKIFIYTFSIFSVLVICLHLAIYFLFPSTYLSHRQET
                     IGQKATAIAQSLEGKDRQSIEQVLDLYSQTSDIKGTVKGEMTEDKLEVKDSLPLDTDR
                     QTTSLFIEEREVKTQDGGTMILQFLASMDLQKEAEQISLQFLPYTLLASFLISLLVAY
                     IYARTIVAPILEIKRVTRRMMDLDSQVRLRVDSKDEIGNLKEQINSLYQHLLTVIADL
                     HEKNEAILQLEKMKVEFLRGASHELKTPLASLKILIENMRENIGRYKDRDQYLGVALG
                     IVDELNHHVLQILSLSSVQELRDDRETIDLLQMTQNLVKDYALLAKERELQIDNSLTH
                     QQAYLNPSVMKLILSNLISNAIKHSVPGGLVRIGEREGELFIENSCSSEEQEKLAQSF
                     SDNASRKVKGSGMGLFVVKSLLEHEKLAYRFEMEENRLTFFIAFPKVAQD"
     gene            complement(28265..28921)
                     /gene="vncR"
                     /locus_tag="ACL3EZ_001383"
     CDS             complement(28265..28921)
                     /gene="vncR"
                     /locus_tag="ACL3EZ_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor VncR"
                     /protein_id="HGR0392942.1"
                     /translation="MKILIVEDEEMIREGVSDYLTDCGYETIEAADGQEALEQFSSYE
                     VALVLLDIQMPKLNGLEVLAEIRKTSQVPVLMLTAFQDEEYKMSAFASLADGYLEKPF
                     SLSLLKVRVDAIFKRYYDTGRIFSYKDTKVDFESYSASLAGQEVPINAKELEILDYLV
                     KNEGRALTRSQIIDAVWKATDEVPFDRVIDVYIKELRKKLDLDCILTVRNVGYKLERK
                     "
     gene            complement(28996..29067)
                     /gene="pep27"
                     /locus_tag="ACL3EZ_001384"
                     /pseudo
     CDS             complement(28996..29067)
                     /gene="pep27"
                     /locus_tag="ACL3EZ_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_198523890.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative autolysis signal peptide Pep27"
     gene            complement(29247..30626)
                     /gene="vex3"
                     /locus_tag="ACL3EZ_001385"
     CDS             complement(29247..30626)
                     /gene="vex3"
                     /locus_tag="ACL3EZ_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit Vex3"
                     /protein_id="HGR0392943.1"
                     /translation="MLHNAFAYVTRKFFKSIVIFLIILLMASLSLVGLSIKGATAKAS
                     QETFKNITNSFSMQINRRVNQGTPRGAGNIKGEDIKKITENKAIESYVKRINAIGDLT
                     GYDLIETPETKKNLTADRAKRFGSSLMITGVNDSSKEDKFVSGSYKLVEGEHLTNDDK
                     DKILLHKDLAAKHGWKVGDKVKLDSNIYDADNEKGAKETVEVTIKGLFDGHNKSAVTY
                     SQELYENTAITDIHTAAKLYGYTEDTAIYGDATFFVTADKNLDDVMKELNGISGINWK
                     SYTLVKSSSNYPALEQSISGMYKMANLLFWGSLSFSVLLLALLLSLWINARRKEVGIL
                     LSIGLKQASILGQFITESILIAIPALVSAYFLANYTARAIGNTVLANVTSGVAKQASK
                     AAQASNLGGGAEVDGFSKTLSSLDISIQTSDFIIIFVLALVLVVLVMALASSNLLRKQ
                     PKELLLDGE"
     gene            complement(30678..31325)
                     /gene="vex2"
                     /locus_tag="ACL3EZ_001386"
     CDS             complement(30678..31325)
                     /gene="vex2"
                     /locus_tag="ACL3EZ_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding subunit Vex2"
                     /protein_id="HGR0392944.1"
                     /translation="MTLLQLQDVTYRYKNTAEAVLYQIDYNFEPGKFYSIIGESGAGK
                     STLLSLLAGLDSPVEGSILFQGEDIRKKGYSYHRMHHISLVFQNYNLIDYLSPLENIR
                     LVNKKASKNTLLELGLDESQIKRNVLQLSGGQQQRVAIARSLVSEAPVILADEPTGNL
                     DPKTAGDIVELLKSLAQKTGKCVIVVTHSKEVAQASDITLELKDKKLTETRNTSK"
     gene            complement(31338..32615)
                     /locus_tag="ACL3EZ_001387"
     CDS             complement(31338..32615)
                     /locus_tag="ACL3EZ_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0392945.1"
                     /translation="MNPIQRSWAYVSRKRLRSFILFLILLVLLAGISACLTLMKSNKT
                     VESNLYKSLNTSFSIKKIENGQTFKLSDLASVSKIKGLENVSPELETVAKLKDKEAVT
                     GEQSVERDDLSAADNNLVSLTALEDSSKDVTFTSSAFNLKEGRHLQKGDSKKILIHEE
                     LAKKNGLSLHDKIGLDAGQSESGKGQTVEFEIIGIFSGKKQEKFTGLSSDFSENQVFT
                     DYESSQTLLGNSEAQVSAARFYVENPKEMDGLMKQVENLALENQGYQVEKENKAFEQI
                     KDSVATFQTFLTIFLYGMLIAGAGALILVLSLWLRERVYEVGILLALGKGKSSIFLQF
                     CLEVVLVSLGALLPAFVAGNGITTYLLQTLLASGDQASLQDTLAKASSLSTSILSFAE
                     SYVFLVLLSCLSVALCFLFLFRKSPKEILSSIS"
     gene            complement(32972..33142)
                     /locus_tag="ACL3EZ_001388"
                     /pseudo
     CDS             complement(32972..33142)
                     /locus_tag="ACL3EZ_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron maturase-specific
                     domain-containing protein"
     gene            complement(33285..33884)
                     /locus_tag="ACL3EZ_001389"
     CDS             complement(33285..33884)
                     /locus_tag="ACL3EZ_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0392946.1"
                     /translation="MQILCYFTITVVAKPNNSGEVHLDVSIEDNQGGSGHNFSSVSSS
                     SQTAKYEGTGYNNNSSLYITIDKTSDATALLKLKLNNVDNQPATEVPSSGITVKLNAK
                     DNAGNWTSASNKKEVTVKIVSAKPTYPDKILVKNPDNIKDTEKNAIIEKLKEANKNHP
                     AGAPTFAKGEGEHANDIVATYSDGTTYYVPLNDVTKYAR"
BASE COUNT         9656 a         7784 c         6295 g        10388 t
ORIGIN      
        1 ttttcaagga ctggttttga tatagcacgt ttaagtaccg acttctgagc tactatagta
       61 gattgaaact agaatagtac acctctactt ctaaaacatt gttagaaatc gatttgactg
      121 tcctgaacga ttcgtcctat tcttatttca ttttattata attgatagtg gtcgccccag
      181 ccagatacct tatccactat ataggcctta ttatcacgtt cctgttcgta gagccacgat
      241 ttcgctatcc cttcctctga cgattcttat ttccagcgtc agacttggga atcgctattg
      301 ggttcaccgg tagtaggtgc ccaccgagga cttacacctc agatatacga catgcccgtc
      361 gtacatcaaa aaaagttgag acatagtgtc ttcaactttt ttacattact ttaactactg
      421 attaaagtga gtttacgtca actttgatac caacaccttg agtagttgtg atagtcaagt
      481 ttgttacgta agttccttta gctgtagctg gttttacttt ttggattgtt tcgttgaaag
      541 ctttaaagtt ttcaaccaat ttttcagctt caaatgatac tttaccgatg attgcttgaa
      601 cgttacctgc acggtcagca cggtaagtga ttttaccacc tttagactct tcaactgctt
      661 tagcaacatc cattgttaca gtaccagttt tagggtttgg catcaagtta cgtggtccaa
      721 ggacacgtcc aagacgtcca acaagagcca tcatatcagg tgtagcgata actacgtcga
      781 agtccaacca accgtcgttg attttagcaa caaggtcatc ttcaccaaca aagtctgcac
      841 cagcagcttt tgcttcttca gcttttgcac cacgtgcgaa aacaagaaca cgtgaagttt
      901 taccagtacc gtttggcaat accattgctc cacggatttg ttggtcagct tttttaacgt
      961 cgatgttcaa gttgtaagca acttctacag ttgcatcaaa ttttgcaaag ttagtttctt
     1021 ttgcaagtgc tacagcttct tctacactgt atgcttttgt gctgtcgatt ttctcaagag
     1081 cagcacgaag ttgtttgctt tttttagcca ttttctattc tccttgtaag tggttcaatc
     1141 gattttcatc tcccacgtca cttctcgaaa tgatgaagtc ttgcgggttt tcagtctact
     1201 atttttctct tcctacggcc ttaagctccc ttgctgtatc caagtacaag cctcagtcac
     1261 ttgcctagta tgaaaagcaa ctaatagact gctgtgagat tttctactgt gttattgatt
     1321 agtcaacaac agtgaatccc atagaacgag cagtaccttc gatcatacgc attgcagact
     1381 ctacgtttgc tgcgttcaaa tctggcatct tagtttctgc aatttcttgt acttgtgcac
     1441 gagtaactgt agcaacttta gttttattag gtgtacctga tcctttttca acacctgcag
     1501 cttttttcaa aagaacagca gctggtggtg ttttcgtaac gaaagtaaat gatttatctt
     1561 cgtaaactga gataacaact ggaatgatca taccagcttg gtcagctgta cgagcgttga
     1621 actcttttgt gaatcccatg atgttgatac cagcttgacc aagagcaggt ccaaccggtg
     1681 gagctggtgt agctttacca gcagggattt gcaattttac aagtttttcg acttttttag
     1741 ccatttttaa atcctccttt gtggttttgg cggtaattag agatttttac ctcccacaag
     1801 tatgctttac acataccttt ccattataca ctatttatct aaaaatgcaa gagaaaactt
     1861 tcatttttaa tcgacataat cgccgccttc aaagccatag tactcttcca aactgagacc
     1921 acttgcagca atttctttgg cttcttttcc aacgtagcgg agatgccatt cttctgccat
     1981 gtagccagtc tccttttcct tgcctttaag atagcgaaca acaaagccat agtcagccgc
     2041 atggtccaag agccactggg ctgccttttc ttcagtaact aaatccccat ctgtcccaat
     2101 caaatcaaaa gcaagacccg tctggtgttc actgtaacct gggcgtgctg agtagcgatc
     2161 tgctgcttcc ttaccatctt gattgacata gtcttggtag agcttagcct gagtttcata
     2221 actcctaaac ccactgtatt ggtcactgat tggatagccc tcagcctgca tagctgcgat
     2281 tagtttgagc aactctgcct tggctgttgg attttctcct ggattgtaat cttttgacaa
     2341 aggataacgt ttattagcta ggataatctc atcgtatttc ccttggatac tataatagct
     2401 ccctttattg ctaacttctg cctttttctg actagaagct tgagatttgc tacctacagt
     2461 tccttccggt tgactgcttt gctccgtttt ttgagtgttt tcttcaactt tggttttttc
     2521 ttgcgaacaa gctgcaaggg tcaatgctag taaaccagat aaaatgacat atcttttttt
     2581 catttctttc ttcctctctc ttaggccaaa tacttctcca attcatgaga taagatttta
     2641 atcatctctt ccagctctgg cgattgtact tggcaatctt ctgccgccat ttcttcccag
     2701 ggcacccacc agactgggcc acggccattc aaaccgtgac tcttcatatc acctgctctt
     2761 cggggaaaaa gatgccaatg agcgtgggca tcgccatttc ctaggagttc aatattcatc
     2821 ttttcagcct caaatgcttt ggcgactgct tcttggacta aactcatttc ctctaaaaag
     2881 cgaagtttta cagaagtttc catatgatgg agttctgtga catgatcttt tgctaaaaat
     2941 aaggtatagc ccttaaagta ttggtagtca ccaataacaa catagcctgt ttctagttct
     3001 tttacaaagt agggattttg cccagcttta atgagttcga ttctctgaca gattaagcac
     3061 attctatgat accgcctcgc tcttaagata agcatcaacc atacgctcag tcgctattac
     3121 tgaatcgatg tgggtgcgct cataagagtg actggactca ataccagctc caagaagtgc
     3181 atgcttgacc tctgcacctg ctgacatcgc tgctgaagcg tccgatccgt aaaatggata
     3241 gatgtcgagc ttaaatggaa tatcttgctc tttagccaag gcaaccaagt gttgacggaa
     3301 gtcatagtga taaggacctg aagcatcctt gacacagata gatactgtgt actcatctgt
     3361 ctgctggtca tctcccatag ctcccatatc cacagccaga tattctacta cctgagcagg
     3421 aatgttagaa ttagcaccat gtcctacttc ttcaaaaact gaaaaagcaa aatgagttgt
     3481 tactggcaat tcaatcttct ctttcttata aatacgaagc aggttgagca aaatcgctgc
     3541 gctgacctta tcatccaaat gacgagactt gataaaacct gtatcagtca caacagttcg
     3601 tgtatcgaag ctgataaaat caccgacctc aatcccaaga gcacgagttt ctttttcatt
     3661 gcttactttt acatccaaac gcacttccat attgtcctgc gtgcgttctg cagttcctgc
     3721 atccttgtag acatggcaag aagtttggtg gatgaggatg gttcctgata ccttttgacc
     3781 tgtgctagcc acatgaacgg tacagttttc accttcaatc atgttccaag gaaaaccacc
     3841 gatacggtcc aatttaagac gaccatctgg tttgacagca cgaacaatag cacccagcgt
     3901 atccacatgg gcagtcacat agcgatgttg ctcatcattt tgacctttga tggtcacatt
     3961 gacaccaccc ttagctgtgc gaactggctg gtaaccaaaa ccttctagag tcttgactaa
     4021 ataattcgaa atttcacgag tgaagcccgt tggcgatgcg atggctgtca gttctttgat
     4081 atattctact gtttgattca tttcttcacc tctttcgcta cctattataa cacatttatc
     4141 atcggataaa aaaagaaaat cactcctgta gacttggcta caaaagtgat ttaagtgatt
     4201 attccatttc aaaaacatcg ctttcttgct tgtttggtag aaccaatgag agcaagattc
     4261 caacaatggc tggcaccaac catgggagag atgccttggc aaaaggaaga acgctaacaa
     4321 gatttgcaag aaactcaacc ttaaacgagc ttcctagtac gcttgcaatg gcaataactg
     4381 taaccacagc aattgtcaac tgcatacctg gttttgaaag ggcaacaaat ttgttgacaa
     4441 tgacaatcat aacgatagca atcgtgattg ggtacaagat aaccagtact ggaattgagt
     4501 acttgataat cgcatcaaga cccaaattgg caatagcaaa tccaatcaag gtaaaggctg
     4561 tcgcataaac cttgtagctg atttgtggga agcgctcatt aaagaactca gctgttgaca
     4621 caatcaaacc aacagtcgtt gtgaagcagg ttacggtaac catagctgca aggaagagtt
     4681 gagctgttga gccaaagatt tcttgagtgg cttgtgacaa gatgtaaaca cctggtgttc
     4741 cacccttcat cgcttcagct ggtactggga aatgatttcc aagaaaacct aaaccgatgt
     4801 aaagagcgct gaaggcaagg gcaacaacga taccaacaac ccaaatagtt gaaatgtatt
     4861 ctttcttact tgaaaatcca agttgtttca aggtttgaac tgcgattacg ctaaaggcca
     4921 ctgaagcaag ggcgtccaag gtattgtaac cttctaggaa acctgtacca aaggcagaag
     4981 cttgataagc agctgaagca gcttgaggac ttgttccacc atatttgata gctcccagaa
     5041 cgaccaagat aacaatcaaa attgcaaaga ctggcgttaa aacacgtcca atgcggtcta
     5101 agatttttga tggattaagc gaaatcaaat aggctgccgc aaaatacaga accgtaaata
     5161 caatcaagcc aagtccttta tttgcatccg acaaaagggg gctaatccct acttcgtaag
     5221 ctgttgtagc agtacgtggg gtagcaaaga atggaccgat tgacaagtaa agaactgaga
     5281 ggtaaagagt cgcaaaccaa ggcgctatct tcgttgaaat ctcgtagata tatcctttag
     5341 gatttagcgt tccaataata agggtcaaga cggcgatacc aacgcctgaa aagacaaaac
     5401 ctgcgatggc aggaagaaaa tgttctccag atagagcacc tagagaaggc ggaaaaatca
     5461 agttccccgc accaaaaaat attccaaaca ggagcaaacc tgttagggta ccttttttag
     5521 ccataaaaat ctccttcata tttataaaat actgacctag tataccacga ttaggagtct
     5581 gaaaaaagca tcacgaggca aatattaaat gttttcaatt ttcttaaaaa taagaattat
     5641 ctaaaaataa aactctccta cccagtccac accaagtagg agaaatgcaa aattttaaag
     5701 ttcttcaaag gctaacatgc caccctggac attgataaca ttataacctt gttctaacag
     5761 gaattggcaa gcacgcgccg atctcattcc agatttgcaa ataatataat gcaagcgatc
     5821 tttgtccaat taatcataac tatcagccaa ttgactaagc ggtaggttgt gggcacattc
     5881 taaatgaaga gctgcaaact catccacttc tctcacatcc actagagaaa gctggtcgtt
     5941 ttggtaaagc tggtaaaatg cgtcaaaggc tatttctttc attctttttc ttctaatact
     6001 cttcgaaaat ctcttcaaac cacgtcagcg tcgccttacc gtgcgtatgt taccgacttc
     6061 gtcagtttta tctgcaacct caaagctgta ctttgagcag cctacgacta gcttcctagt
     6121 ttgctctttg attttcattg actataaaat ggttttaatt ctttttttca aatctggcac
     6181 tacttctgcc tcaaaccaag gatttttggc catccagatt tgatttcgtg gtgatgggtg
     6241 aactagcgga aaataggctg gcagatagtc tttatagtgt ttcaccctct ccgttacctt
     6301 cccactgatt ttctcctgta aatagtaggc ttgggcatat tgcccaatca agagggttaa
     6361 ctgaatatca ggcaattcct gtaagagctg cggatgccat ttttctgcaa aacctgtacg
     6421 aggcggaaga tcacccgact tgccatgtcc tggaaagtag aaatccatag gcaaaacagc
     6481 aaaataacct gaattgtaaa aggtatcttc atccacacct agccagtccc gcaagcggtc
     6541 accactttta tctttccagt aaaggcctgc ttcttgagtt ttaagtcccg gagcctgacc
     6601 gatgatattg atgcgagcag tttttggcgc tgcaaagaga ggctcaatgc cacgctctgt
     6661 atagctggca ttctgtgaat ccgccatgat agcctgtttg attctttcga tttgagacat
     6721 ctactttccc tccaaaaaga agtccaagca taagatctca gacttctatc gttttatttg
     6781 atcaattcgt aaatagcttc ggcatagatt gctgctgctc ggaagagatc gtccaaggcg
     6841 ataaattcat tggcttggtg catggtatca attgagtctg ggaacatagc accataggca
     6901 actccgcgct ctaacaagcg accaaaggtt ccaccaccga tgacttgttc atgaccttta
     6961 aagccagttt gtttttcata gatattcaac aaggtttgca caagtggatc ttccattggc
     7021 acatagtgag gcgtgtgacc gtgttcagac aggctaacag aaacaactgg caagttttca
     7081 aggattgact tgatttgttc tggacttgtt ccttttggat agcggatgtt gagggcaatg
     7141 gtattatcag cacttgtttc atcgaagcgg aagacgccgg cattcataga aagagcaccc
     7201 atcttttcat ccacatgagc aatcttaaga ttttcaccct catgatcgtt caagagaatt
     7261 ttacctgcga tgtcaaggta gtctttggct ggaccagcaa agccaaactg actgaggaag
     7321 agggcaaggt aagttgcgcc attgacacct gaagcaggca tagcaccgtg ggctgattta
     7381 ccaatgatcg tcaccttgta tttgccagct tcttcttgga gttctcctct aagtttgtgt
     7441 tctgcaacaa aggcatctag tttagcttgc aagtcagcca agtcacctga aacgactgct
     7501 gttgctgatt ctggtaccat attttcacgt aaaccacctg taaagctgtg aagacgggca
     7561 acacctgtat tttctcctgc aaagtggagg tattccgtga tatttccttt ttcaccattg
     7621 atgattggaa attcagcatc tggtgagaaa ccgaaatctg gtttggcaag tcctacgtgc
     7681 tcaaagtagt agtccatgtc tgcccagcct gattcttcgt ctgttccaac gatgaagcga
     7741 actttcttag aagttggaag acccaattct ttgatgattt tcaaaccata gtaacaagct
     7801 gttgtaggac ccttatcgtc cgaagccccg cgcgcataaa ggcgaccatc tttgatagtt
     7861 ggtgtgtaag ggtctgtgtc ccaaccgcta ccagcaggca ccacatccat atgggcaaag
     7921 attccgagaa cttcttctcc atcaccaaac tcaaaatgtc ctgcatagtt atcaacattc
     7981 ttagttgggt agccatcgcg gtctgcgatt tcaaggaatt tctccaaggc ttttactgga
     8041 ccaggcccaa atggatgctg ggcatcagcc ttgctgtcat cacgttctga attgatttcc
     8101 aaaaggctaa acaagtcagc caagaggtct tctttgcgtt tttctacttc tgctgtaaaa
     8161 tcaattgctg tcattttttc ttctttctat cttttctcga tgatttcatc tactggcaag
     8221 cggtagcttg gttccaattt ttcgtctgta taacccactg tgatcaagag ttctgggcgg
     8281 aaacggtctt cgatttccaa aacttcatta acttttgatt tgtcaaaacc aagaataatg
     8341 ttagaaccaa ttccttggtc tgtcaatgca agaaccaagt tcatggcaac caaacctgca
     8401 ttgagagcta ggtagtcgct gacttgttgt tcattgtagc gtgcaaattc agctggcaaa
     8461 tttttcatga agtattgaag ttgttcttct gagaaattgt tagcaccacc aactcgggca
     8521 atcttacgag cgcgtttggc aaggtctgta tctgtaaata gggcaatggt tacaggtgct
     8581 gatgatacct gctcaaagtt tgaaccataa gccaactttg ccagttcagc atttttctca
     8641 cgaacaacta caaatttcca aggctggctg ttgtgggcgc ttggcgccaa ggttgcaatt
     8701 tcgatagccg tacgcacatc ttttggatca acaggcttat cagtgaaatg cttggtcgca
     8761 tgacgttttt tatttaattc aagaaatttc ataatcgatt tccttttcta attctactgc
     8821 ttccattcta ccataatttg aaagagcttg cagggatttt tcatgattaa gtttttctat
     8881 cacagacata aaagatatat attggtttat caggaaagtt tctgataaac tagcaagtac
     8941 tttacatttg aatggagaca gtatgaaaaa atttagccta ttactagcta tcctaccatt
     9001 tttggttgcc tgtgggaatc aagctacacc caaagagact agcgctcaaa agacaatcgt
     9061 ccttgctaca gctggcgacg tgccaccatt tgactacgaa gataaaggca atctgacagg
     9121 cttcgatatc gaagttctaa aggcagtaga tgaaaaactc agcgactacg agattcaatt
     9181 tcaaagaacc gcctgggaaa gtatcttccc aggacttgat tctggtcact atcaggctgc
     9241 ggccaataat ttgagttaca caaaagagcg tgctgaaaaa tacctttact cgcttccgat
     9301 ttccaacaat cccctcgtcc ttgtcagcaa caagaaaaat cctttgactt ctcttgacca
     9361 gatcgctggt aaaacaacac aagaggatac cggaacttct aacgctcaat tcatcaataa
     9421 ctggaatcag aaacacactg ataatcccgc tacaattaat ttttctggtg aggatattgg
     9481 taaacgaatc ctagaccttg ctaacggaga gtttgatttc ctagtttttg acaaggtatc
     9541 cgttcaaaag attatcaagg accgtggttt agacctctca gtcgttgatt taccttctgc
     9601 agatagcccc agcaattata tcattttctc aagcgaccaa aaagagttta aagagcaatt
     9661 tgataaagcg ctcaaagaac tctatcaaga cggaaccctt gaaaaactca gcaataccta
     9721 tctaggtggt tcttacctcc cagatcaatc tcagttacaa taacactctt cgaaaatctc
     9781 ttcaaaccac gtcagcttta tctgcaacct caaagctgtg ctttgagcaa cctacggcta
     9841 gcttcctagt ttgctctttg attttcatat tgagtataag atatattaaa agcgatggga
     9901 tcagccaatc gcttttttag tttgcattgg ttattttagg aaactcttac aaaaaatcaa
     9961 aaaaattctt cacatcctct acatacctat gcttttctat taagcttgct aatagttcca
    10021 gattgtgcct ctgatagtta tcttcacgac gtagttcttc atacatttcg ataaagggaa
    10081 aacccttgga tttggcaaat tctaactcag cctcgtaatc ataagcgact ttacgaaata
    10141 ggatatttac caattcccca tcttcaacct ctatcacggc atactgggca cggtgatttt
    10201 ttaacgcctc ccaattaaaa tagggcatgc caatcgaccc tggattgatg atttgttgcc
    10261 cttgactacc ataacgaagc aactacttgt gaacatgacc ataaactgcc acgtccgttt
    10321 ccgcatctag cagttggtca aatttctctg tatcattctc aactagcaag tcaccaccat
    10381 agtttttgtc aggtaaatta tgagagatag aaaagcgcaa tccgtcaatt tctttctttt
    10441 ccagcaaagg caagcttcgt agccagacaa tcgttgcagg atccattcgc tccatcaaat
    10501 actgtgtcat acgcaagagc tgaacttcct gtgggtcttc taagccatat tgcccatcta
    10561 aagcctcaag gacacaatca tcccaattgc ctcgaacact tgccgtgata ggaagttcct
    10621 ttaacagagc gaccaagtca tttgcacctg gaccagggag gaaaatgtct cccatgagcc
    10681 aatattcact ggctccttga gttttagcat ctgcaatcac tgcttctagc gccgtcgcat
    10741 tgccatgaac atctgataaa attgcgattt tatggtttat tgtggtttcc ttccgtttgg
    10801 taatctactc tttcttccgc cacttgaagc aagatttctg tttcctgcgg gttcaacttg
    10861 gtttgcacag cctctgctac tgctcttggt actccaactt cgacaatctc atccacactg
    10921 gcttccttga ttttggtcag agacttgaag tgcctcatga gattttgctt gcgtttaggt
    10981 cccagaccat caatcccatc caattgagat gagaaagaat ttttggagcg cagttggcgg
    11041 tggaaggtaa tggcaaagcg gtggacctca tcttgaatgc gttggaggag gaaaaattcc
    11101 tgagaattgc gagacaagtc caccacttcc agcggatctc caaagagcaa ttcatgggtt
    11161 tggtgcttat cattcttttg cagacctgca attggaatat ccaagcccag ttcttcttgg
    11221 atgacttgct tagcaatatt gacttgacct tgccccccat caatcacaat caaatctgga
    11281 ggagtcaaag cctcacgctg tactcgacca tagcgtctgc gaatgacctc tcgcatactg
    11341 gcatagtcgt ctggcccgac tacggtcttg attttatact tacggtaatc cttcttacta
    11401 ggcttgccgt tgacaaagac caccatggct gaaacaggac tagttcccat gatgttggag
    11461 ttatcgaagg actcgatgcg aactggggtt gggatttgaa gcaagcgtcc tagattttca
    11521 atagctcctt gggtcttctc gacagatttc tctagcaggt tgaacttctg ctctaggcta
    11581 acacgggcat tttttatagc taaattgacc agctgctttt tctctccacg ttgaggctta
    11641 agaatcttgg aatccaccaa ggccttgaca gcctcttcgt caatatcttg cggaatcagt
    11701 acctcattgg gaactagatg ggatttttct tgatagaatt gtcctacata ggtcaaaaaa
    11761 tcctcatctg gatcattgaa gtaggggaag agattgacat cgcgctcgat gagcttaccc
    11821 tgacggacaa agaaaacctg cacacacatc cagcccttat ccacatagta gccaaagaca
    11881 tcgcgatttt ggagatcctt agccatgacc cgttgcttgg ttcgaagcgt tccaatagcc
    11941 tgaatcaggt cacggtattc cgccgcacgt tcaaactcca tagtctgggc tgccgctgcc
    12001 attttgccct ttagctcatc aatgattttg ttatcctgcc ctttcagaaa atcagaaacc
    12061 tcctgggcca tagacttgaa ataaatctca tccttcttac agatggtgtg ggccatgcat
    12121 tgaccgatat ggtaataaaa acagacctta gagggcgggt tggtacactt acgaaaaggg
    12181 aatatccgat ccagcaaccg cttgatttca ttggctgccc ccacatcggg atagggtcca
    12241 aaataaagac ctccgtcctt tttgacctga cgagtgataa tcaagcgtgg atagcgctca
    12301 ttggtgattt tgatgaaagg ataggacttg tcatccttga gcatgatatt gtacttgggc
    12361 ttgttttcct tgatcaggtt gatttctagg agaagtgcct caatattaga ctccgtaaca
    12421 ataaattcaa aatccacaat ttcagacacc agagcctctg tcttggtatc atgacttcca
    12481 cgaaaatagg accgtactcg attacgcaga tttttagcct ttcctacata gataatggtg
    12541 ccatttttat ccttatgaat gtagcaacca gggctggtcg gcaagagctc tagttttgat
    12601 ttaatcaagt tgttcatagt tccattatag caaaaaaagt agggaaagat agtaccctac
    12661 tcactagtct catatatttt tcggaggttt gcaacatcct cttcctggat accataaaag
    12721 gaacctgctg gttgcatgac agacttctca tctgtatggt ccaagccaat cgcatgacct
    12781 aactcatgtt ctgccgtatg gacaaggcgt tcataggagt agccatagta tggattggac
    12841 aaataataat gattcaaccg caccgttacg gacaagaatt gccctgttaa gagattagtt
    12901 tgactttccg cctctcctgc cacaggagtg cctccgtcgt tcatctccgt agccgtaata
    12961 tccgccttac tagactcagt cacgagttca aagttaaaag caccagtttg attccagttc
    13021 tggattgctt ctaaataagc ctcttgaaag cgtgaatcca tctgcggatc caggtaaata
    13081 cgagcagagg cctgtgccca ccttccttca gaatgctggt gactatctgt ctggcttaac
    13141 ttaggcagtt gccctgtttt ctcccattgg tcaatacttt gttgaccaat ttttactgac
    13201 cgttctgctt gctttagcgc tccttgaaaa tctccgttca gataccagag aagtccgaaa
    13261 gcaagcacac ataagagcac aactatccaa accagacgcc aaaacaaacg ccacacaaaa
    13321 gaaaagaaag cccctatcaa acgaaaaagc cagcgcatgt ctctccacct ttctagcaaa
    13381 taagaattat tttactaaaa gaagctaaaa gaaatctaaa tactgacttt ttcatcttaa
    13441 cgtcctacta tttttttgag taactggata gctttgtatt ttaaaggaga tggatggtaa
    13501 cggaaagtac ctgctttgcg tacaatatag ccattaaaat tctgtttaaa acgcaaaaca
    13561 ccatcacttc catcaaaaat cccttgaatg cctaggaagt tgtatttagg tattccacgt
    13621 tttatgcttt ccaacataac atatttttga agcagggcag gggcatagaa cttattaaac
    13681 tcagtgtagg aaccactaaa gagataagtc gtttcctgag gcatataaac aaataaactc
    13741 ccagctaaaa caatatcttc ttctccatat ttttcaatca agtctcgcgc ttctgctttt
    13801 cgaacttcaa acgtttcaaa ttgactagaa tattctctca gttgattttg ttttttctca
    13861 gaatgaggat ttttactcaa atcaagtcgc aacttgtcca agttttcttc tagtttactt
    13921 tgttcacctt gcaatttgct catatagtcc gaaaaattta agcttgctat gagaaactcc
    13981 gcttgttctc caaaagtatc ataaaaatgc tcataatatt ctaaactttt atcactatat
    14041 tctctacgtt cagaggtttc ttttgttata ttcttaaaaa tcgatagttc ttcacgtttt
    14101 aactttttca accgaatgcc aaaggtttca gcctttttca ccaagggttt accctttttg
    14161 ctaaaacttt taagcaaact cttttcagtt aattcagtta aatctttata gtataaccaa
    14221 tctggttctc cacctgggta acctgttgtt aagccatcaa attgataacc taaatcagtc
    14281 aaaccttgaa taatactttt tttctcagca tctattggat taccttggct atcaaaagtt
    14341 tgataagttt cataaggttt tacaagcaac tctaatacac cattttgctt ggcatattct
    14401 tttaactctg cataaaaaac tggaagagca tcttgttggg tataaattgg ccccgaattg
    14461 agttccatat gcagaccacc cagcatgggc aagctataaa ccagagctgc aacttgaatt
    14521 tctccttctt gtttcaaagc aagataaaca attcgagccc ctcttttttc tagcaaatcc
    14581 cccatctgga cagattgcat aaaggaacga gaagaaacct gatcagaata agtctgaaac
    14641 tcttctttcg tgagtgttgt tagtgccata tacttacttt ctatgttttt ttcttaatgt
    14701 tttacggaaa tcaagagcaa gtcttaacag aggatagaga ggatgagtgg gcattgtaaa
    14761 ttcacccaag tattcttcaa tcgttggatt aaatttttcc ttaaaatgat aaagtccacc
    14821 attgagagag ttttcaacac cacctaaatt ttgccagacc atacctcgct caaaggcata
    14881 gcgagccgtt tcataccatg ttaaaattgg tgcattgtaa cgtttaaaat catcatccat
    14941 accagcatat atattaacag aggtagtacc aaattccaaa ctcaaagtag ccgctaaagg
    15001 aactctcgct tgacctacat ctatatattc ctgcaagaag gtcaattcct ctaacaaacg
    15061 ttctttttcc ttcttctgcg cttctacttt tgaagttcga gtcgactcag taaacgtctc
    15121 ttccaaggct ctatttttcg ctaactgttc ttctaattct tgcgaacgtt tagaaacatc
    15181 caaggtggcc aaggtgatat aggccttgtc cttaaaatta tctaacaatt ttttataata
    15241 ggcttcattc ctcaaatgaa tctcttttcg cttctcagtt tttttcatca actccgaaaa
    15301 tgaatctaat agttccagtc caccatattg aatctcaagc cctttgtttc gtgctgttcg
    15361 aatagcctgt tttgttgact tggaaagttt atcttcttca aaattttcct tgtatatttt
    15421 cgcctgaata cgaggttgaa tggtgtctcc catttcctcc gtttttcctg accaccttac
    15481 tcccatttgt tgcaaactat caataatagc cagattttca ggaaattctg tcttttcctg
    15541 attgattaaa ctttgagata ggcaaatact tgggtcaaaa gtcacaaaaa ccgctctctt
    15601 actgcgagca taggacttaa tagactgaat ggcaaaattc aagagttctt tatccccata
    15661 atccaatata ggtcctcttg ggatgtaaaa cattttatag cctagcggaa gagttctaat
    15721 caaaatacta gctgtcgcca gtaatttttc ttccctgtaa acaccaaact tctcatgttg
    15781 ccaattagac ttaacttcct cccaagcact actttgtaat acattggcta attcatgttc
    15841 tttgacaaac tgatcatatt ctaatgtggg aatgccaatt tgataacggt acatttccta
    15901 ctctctttcc tccagtattt tattactatt ctactacttt cgtttgaaaa gtctagtgaa
    15961 aacatatttt attttagttc tactccccct atgctgaagt tcaaactaag tcagtctctc
    16021 ttctaatttg aaatcaattg gtagggttgt taaaaaaact tccaattgtt tttcccagta
    16081 gtaccactcg tgagttccag cactatggct ataggtcaca tcaaaaccta gttttttgag
    16141 atttttcact gcgagattat tggcttcgta caagaaatcc tgttcgccac accacgccca
    16201 aagtttggtc tttttatccg attttttagc cagactttca agagaatagg gactagttgt
    16261 ccagtctcta atctctccaa aaacacctct ccagtaggct ggacttccca gattttgact
    16321 ttcaggagaa aagttttgaa agctgagggc acctgaaaaa ctagctgcat gagaaaaacg
    16381 atttgtcgta agagccagtt tgaagcagcc gtagcctccc atagaaagac cagcgataaa
    16441 ggtcttttca cgcttgctag tcatattagg gaagaagcgt ttcagaacct gtggcaattc
    16501 ctctgctaga gccatgtagt agtcaaaacc atactgggta tcggtgtacc aaccattgct
    16561 ggtattgggc ataacaacga tgagattagt tcctcgaagc aagcgttcta cattggtccg
    16621 cttaagccaa ctattatgat ttccagacat cccgtgcaaa aggtacaaga cgggaatatc
    16681 ttcacactct ggttcttcca ctcgattggc atcagggtag aggacattca ccccccactc
    16741 catatccaat acttgtgagt aatactcgat tttcattact gccatgattt tctccttcta
    16801 tttttctata agaaaaagcc gaaactcgac tttctctctg tttatttcaa cgattatttt
    16861 gcttccatga ctactggtaa aatagctgga cgacgcttgg tttggtcaaa gagatacttg
    16921 gtcaaattat ctcgaacctt ccctttaaga tctgcccagt caaagtcatc tccttgaaga
    16981 tactcttcta ccgtttggtt aatcaattct gaactttcac ggagaatatc gcgactcttc
    17041 ttgagataaa caaatccgcg cgtatgaaca cgagccctag ccacaatttt cttctcacga
    17101 cggttgactg taatagccac gatgaaaatt ccatcctctg acaagacctt acggtcacga
    17161 agaacaacat ttccaacatc accaatggca ttcccatcaa tcaagatatc tcctgctgaa
    17221 accgatccag ctggaacaaa gtctccattc tcgtaagcca tggtcgtccc ctttttagga
    17281 atgaagatgc gttctggcaa catcccaact gccatggcag ccttagcgtg agcatccaac
    17341 tcacgatact ccccttggac agggaagagg tacttaggtt gcaaaagatt gatcatcagc
    17401 tgcaaatcac gcacatttcc gtgccctgat acatgtaaac tttgggtaat caatttgaca
    17461 accccacctg cctgataaat catattttcc acacgcgcaa caaaggcttc tttagcaata
    17521 gacggagccg tagcaatata gaccaggtcc ccatccttga tttctacata acgatggcga
    17581 ccaatcgaca tcttacgaag tccattgata ggttcaccca tacgacctgt ctcaagaata
    17641 atcaactcat ggtcttcaaa gcgagacata tctttaggct taatcaagag aatttcgttg
    17701 gctaaagaca acttcttaag acgaatcgct gtgcggacga tattttcaat atcaaatcct
    17761 gtcaagacga tacgtcgacc tgttttatcc gcagcgtcaa aaatctgctg aatacgagaa
    17821 agattactgg aaacagctgc aacgatgata cgaccttccc agtcagcaat agtttgggta
    17881 atttcatccc taacttcact ttcactagcc acctgaatat tgctgtctgc attggccgaa
    17941 tcactgagga gagccaggac gccgtcacga ccaatctctg ccaaacgagc aaaatcagtt
    18001 gcataagatt cactagccgt ttggtcaaat ttgaagtcac ctgtataaac gatgcttcct
    18061 tccgatgtct tcaagacaat tcccagactc tctggaacgg agtaagtcgt agggaagaag
    18121 gaaaccactg tcccaccaaa atcaatctcc gtattctcat caatgacatg gaaatcatta
    18181 aatttcttaa cggcatcatt tcctttgaca aagagctttg ccaactcaat ggtcaactca
    18241 gacccaaata caggaacttt agcctctgcc aagagataag gtagagcacc aatggcatcc
    18301 gcatgcccgt gggtcaagaa aaccccagca atacggtcgc tattttcaaa aaggtaatcc
    18361 atgtttggaa tcaccacatc gacccctaat tgttcatttt caggatattt taaccctaca
    18421 ttcaaaacaa aaatggactc tccaatttca gcaatgtaca tattttttcc attctcacgc
    18481 acaccaccaa gtgttgttaa actgatatta ctcatttttc ctccaaaatc ttagtttatc
    18541 ttgattatag ggcaactcta ccctcttatt ctaaaagttc taatactttc agccgaatct
    18601 tttcctacca ttataccatt tttttgatga ttttcaaaat gaaggtctgt tttcaaaaaa
    18661 gagttgattt cccaactctt tcctaacttc tactcttttt ccatcaaaaa atcataaatt
    18721 tcttgcaccg tacccagcgc catcatttct tggtctttaa cggtttgttt gagattttgg
    18781 taaatttgac tttctcctat ctcccgcttt ggcgcctctt tattgactgt catcacacca
    18841 tcttttatcg tcacaaagcc tagttcttca aatacttgaa tcatcttgac cagcaagatt
    18901 tgttgaatat taagatatgc agccaaatct ttcagcttgt agcgaatatc aaactctggg
    18961 aactggtaaa tagtcttgta caatttggca aactgatctc tagtcccata acctgtcaga
    19021 taataggcct tgtcaatatc atttttgaaa tagacagcag agaaatgctg ttcctgaaaa
    19081 atggtcttca gctgagtaat atcctctgga atgtttttta cgacaacagc ttcactagcc
    19141 gcaagatttg gcagttctcc aggaaaatcc aagactggaa caccttctgg caagactgca
    19201 ttttttccac gaatgttaaa aagttgaaca ccttccactc gcgcatccat catcatcaac
    19261 tggagggcag tttggccgtt ccattggttg acagacaatt taaccgctaa ctctagattc
    19321 ttggtttgag aaaactctgt cgcccatctg ccttgaccaa aggctaccac ttcaaaactc
    19381 acctcaccct tggaaatttt cagctttaga tgggcattac ctgcccccat agtacgagca
    19441 ctttcgacct gaaaattctt gatataaaaa ataggtttct gattatccat tccaaaagga
    19501 gctaaacgtt caaaactttt gaccgtttcc aagctaagtg cctccaaatc caactcttca
    19561 tctaggttta acttattctt gccaccagca tctgcacctt tttcacgaac ataatcttcc
    19621 aaaatctgag ataaatctga gagttgctca acttccagcg tcatacccgc tgcacctgca
    19681 tgacctccaa aggcgatgaa gaggtctcga tagggatcca gagcttcaaa aatatcgacc
    19741 gcttccacac tacgagcact gcccttggca cgaccgtctt ctatattaag aacaatgact
    19801 gtctgtccca attcttccaa taaacgacca gccacgattc ctagaacccc aggattccag
    19861 ccttccttgg ccaagacctg aaccttcttc tcaggatcca ccatggtctt ggcttcttca
    19921 tagatagact gaacgatttc cttgcgctct tcgtttttct ggtgaatcat aagggcaatc
    19981 tcatgcgctt cctcatcatc aaatccagtc aacaaatcaa tggcaggatt gggatcatcc
    20041 aagcgaccca aggcattcaa acgaggagca atctggaaac caaccgtttc ttctgttact
    20101 tcgttagcag caatcccagc catgtccagc atttcttgca gaccaatgcg ctgggtatga
    20161 cccaacattt ccagaccata ttgaactaag atacgatttt catccgtcag actcaccata
    20221 tctgcaatag ttccaatagc gaccaaatca agcaattcca cttgcacttc ttctaacagg
    20281 gcacaagcca acttgaaagc aactccacaa ccagccaaat atttaaaagg ataatccgca
    20341 tctggatgtt caggatggac aatagcataa gcatctggca gggtttcagg tatggaatga
    20401 tggtctgtca caatgacatc tactcccata gactgagcca atgcaatagc ctcatgacca
    20461 gcaaccccat tgtccaccgt cacaatcaag gaaattcctt cttgctcgat aaagtattta
    20521 taaacactag cattagggcc atagccatcg gtaaaacgat ttggcaggta aactcggcac
    20581 tccgcaccaa gttgttccaa actttccttc acaatagaag ccgaagtcat gccatccgca
    20641 tcatagtctc cataaacgag aatattttcc ccttcttcaa tagcctgacg aatccgctcc
    20701 actgccttgt ccatatcatg gagcagataa gcatcatgta agtcctccaa ggaaggttct
    20761 aaaaacttct tcagactttc ttggtcctga atccctctct caaacaataa ccgagccacc
    20821 tcaggaccca gtccagcctt cttggctatc tttgtaaaat ccgcattttc tacctgcagg
    20881 gcaaactgcc attcataagt aggtgttatc aaaaagacat ccactctttc taagaattct
    20941 attgcttcat tataacatga tttagacgtt ttctctatcc agattgcttt tttataacat
    21001 tttatagtat attgaaacta gaatagtaca cctctacttc taaaatattg ttagaaatcg
    21061 atttgattgt cccgatcgat ttttcctgtt cttatatcac tatagtgaat tttttcagat
    21121 atgatttgac aagaacattc ttttatcgta gaatcatgtt ataaaatcta acacaaggga
    21181 gatctctcat ggctttagta gaatttaaaa acgtcgaaaa atattacgga gactaccacg
    21241 cactccgcaa catcaatctc cgttttgaaa aaaggacaag ttgttgtcct gcttggacct
    21301 tctggctctg ggaagtccac tcttatccgt acgatcaatg gtttagaggc tgttaacaaa
    21361 ggaagtctcc tagtcaatgg gcaccaagtt gctggtgcca gccagaaaga tttggtacct
    21421 cttcgcaagg aagtcggcat ggtttttcaa cattttaacc tttatccaca caaaacagtg
    21481 ttagaaaacg taacacttgc acccattgaa gttctaggaa ttgataaaaa agaagctgaa
    21541 aaaaccgccc aaaaatatct ggaatttgta aatatgtggg acaagaaaga ttcctatccc
    21601 gccatgctat ctggtggaca aaaacagcgg atcgccatcg ctcgtggtct tgctatgcat
    21661 ccggaactcc tcctctttga tgaaccaaca tctgctcttg atcctgagac tatcggagat
    21721 gttctagcag ttatgcagaa actggcgcat gatgggatga acatgatcat cgttacccac
    21781 gaaatgggct ttgctcgaga ggttgcggac cgcattatct ttatggccga cggagaagtt
    21841 ttagtagata tgacagatgt cgatagcttt tttgacaatc caagcgaacc tcgtgcccaa
    21901 caattcctca gcaaaattat caaccacgaa agtgacaaag tcaaataagg aggcgcctat
    21961 gaaaaaaaat tctttttatc agcattattg attagccttt tcggccttgt tgctgccaaa
    22021 ccagtccagg ctaatactag tatcgcagac attcaaaaaa gaggcgaact ggttgtcggc
    22081 gtcaaacaag acgttcccaa ttttggttac aaagatccca agaccggtac ttattctggt
    22141 atcgaaaccg acttggccaa gatggtagct gatgaactca aggtcaagat tcgctatgtg
    22201 ccggttacag cacaaacccg cggccccctt ctagacaatg aacaggtcga tatggatatc
    22261 gcgaccttta ccatcacgga cgaacgcaaa aaactctaca actttaccag tccctactac
    22321 acagacgctt ctggattttt ggtcaataaa tctgccaaaa tcaaaaagat tgaggaccta
    22381 aacggcaaaa ccatcggagt cgcccaaggc tccatcaccc aacgcctgat tactgaactg
    22441 ggcaaaaaga aaggtctaac ctttaaattt gtcgaacttg gttcctaccc agaattgatt
    22501 acttcccttc acgctcatcg tattgatgcc ttttccgttg accgctctat tctgtctggc
    22561 tacactagta aacgcacaga actactagat gatagtttca agccatctga ctacggtatt
    22621 gttaccaaga aatcaaatac agagctcaac gactatcttg ataacttggt tactaaatgg
    22681 agcaaggatg gtagtttgca gaaactttat gaccgttaca agctcaaacc atctagccat
    22741 actgcagatt aaggaggaca ccccatgaca gatttatcat cttggacagc ctattttcag
    22801 gattttggac aatttttcaa tggtttcctc tttactcttg ccctagcgat tggatccttt
    22861 atcctcgcca tggtcttagg aatcttcttt ggtgccatgt caaccagtaa acgtccaatt
    22921 ttacgcattt tagctcgcat ctttgttgaa ttttaccaaa atactcccct cttggtgcag
    22981 tttgttattg ttttttatgg cctacctctt atcagtgacc atatcatcat gattccaatt
    23041 tattggacag ccgttctctg cgtgggactc tatcacggcg cttatatcgc tgaggttatt
    23101 cgttcaggga ttcagtctat tcctagtggt cagatggagg ccgccttgtc gcaaggtttt
    23161 acctatatca gtgccatgcg cttgattacc ttgcctcagg ccttctgcat cattctacct
    23221 ccattgacca accaaattgt taacctcatc aagaacacct ctactgtagc tatcatctct
    23281 ggagtagact tgatgtttgt gactaagtct tggtcggctc tcaacggaaa ctatatccca
    23341 gcctttttag gtgctgctct tctctacttt gccctatgct tccctgttgc ccagtttggt
    23401 cgcaagatgg agcaagccaa caaaaaagcc tattcacttt aggaggttac tatggaatct
    23461 attttagaag ttttaacccc agataaccta gtctttatct ttaaaggatt tggcttgacc
    23521 ctctatattt ctctgattgc catcatcctc tctactatca tcggtacggt gctagctgtc
    23581 atgagaaatg gcaaaaatcc tatcttacgc attatttcca gtatttatat cgagtttgtg
    23641 cgcaacgttc ccaaccttct ctggattttt actatctttt tggtgttcaa aataaagtcc
    23701 acaccagcag gtattacagc ctttactctc tttacatcag cagccttggc tgagattatt
    23761 cgaggcggtc tcaatgccgt agacaaggga caatacgaag caggaatgtc acaaggcttc
    23821 acctcagccc aaatcctcta ctacatcatt ctcccacaag ccatccgcaa aatgctacca
    23881 gccatcattt ctcagtttgt tcccgtgatt aaggatacca gtctcctcta ctctgttatc
    23941 gccctacaag aactctttgg agccagccaa attctcatgg gccgttattt cgaaccagag
    24001 caggtcttca gtctttacat cctgattgcc ctcatctact tcagctttaa cctagcaatt
    24061 tctagcctgt ctcatatgct agccaaacgt tggcaacaag ctgcagaata atactcttcg
    24121 aaaatctctt caaaccacgt ctgcttcacc ttgccgtata tatgttactg acttcgtcag
    24181 ttctatccac aacctcaaaa cggtgttttg agcagcctgc ggctagcttc ctagtttgct
    24241 ctttgatttt cattgagtat aaacagccac tctccagttc aattggagag tttttttgat
    24301 gagagtagat atttatagac ctcaatttga caccatacat tttctatgat aaaatgtaac
    24361 aaatttattt acaacaaatc gaaatctaaa tgaaatggaa ttttctatga aatcaatcaa
    24421 aggactactc tttatcatag ctagttttat cttgactctt ttgacttgga tgaacacttc
    24481 tccccaattc atgattccag gactagcttt aacaagccta tctctgactt ttatcctagc
    24541 cactcgtctc ccactactag aaagctggtt tcacggtttg gagaaggtct acaccgtcca
    24601 caaattcaca gcctttctct ccatcatcct actaatcttt cataacttta gtatgggcgg
    24661 tttgtggggc tctcgcttag ctgctcagtt tggcaatctt gccatctata tctttgccag
    24721 catcatcctt gtcgcctatt taggcaaata catccaatac gaagcttggc gatggattca
    24781 ccgcctggtt tacctagcct atattttagg actctttcac atctacatga taatgggcaa
    24841 tcgtctcctt acatttaatc ttctaagttt tcttgttggt agctatgccc ttttaggctt
    24901 actagctggt ttttatatca tttttctata tcaaaagatt tccttcccct atctagggaa
    24961 aattacccat ctcaaacgct taaatcacga tactagagaa attcaaatcc atcttagcag
    25021 acctttcaac tatcaatcag gacaatttgc ctttctaaag attttccaag aaggctttga
    25081 aagtgctccg catccctttt ctatctcagg aggtcatggt caaactcttt actttactgt
    25141 taaaaattca ggcgaccata ccaagaatat ctatgataat cttcaagccg gcagcaaagt
    25201 aaccctagac agagcttacg gacacatgat catagaagaa ggacgagaaa atcaggtttg
    25261 gattgctgga ggtattggga tcaccccctt catctcttac atccgtgaac atcctatttt
    25321 agataaacgg gttcacttct actatagctt ccgtggagaa gaaaatgcag tctaccttga
    25381 tttactccgt gactatgctc agaaaaatcc caattttgaa ctccatctaa tcgacagtac
    25441 gaaagacggc tatcttaatt ttgaacaaaa agaagtgccc gaacatgcaa ccgtctatat
    25501 gtgtagtcct atttctatga tgaaggcact tgccaaacag attaagaaac aaaatccaaa
    25561 aacagagctt atttacgaag gattcaagtt caaataagta atcatactct cctgggaaat
    25621 cccaggagag ttttttatag ccaaatgaaa taagacagga acgatggaat tttggcattc
    25681 aaatcaattg ataagactat tttatagtgg agtgaaatag gatacgaaca aattgattag
    25741 gaaaatcaaa tgaatttata gaaatctttt agcagttatg ttatcctatt ctagtttcaa
    25801 aacgctatag aagcagcatt gtactagtct agattcagtt tactatacta aaacgagtag
    25861 cttgaaatca aaaaacccac cctcacaggc aggttttatc tgtattattc agctagatta
    25921 tgctttacct tctgaaccga atacgtcgat acgttcttca accgatgctt ggatagcttt
    25981 tacaccgtca gccaagaatt tacgtgggtc gaagagtttt ttcttgtcgt attctgcttc
    26041 gtttgcttcg tagtcacgag caaatttacg agttgcgtta gcgaatgcga tttggcattc
    26101 tgtgttaacg ttaactttgg caacaccaag tttgatagct gcttggattt gctcatcagg
    26161 aatacctgat ccaccgtgca atacgattgg gaatcctgga agagcttctg tcaatttttg
    26221 caagtggtca aggtcaagac cttcccagtt tactgggtaa ggaccgtgga tgttaccgat
    26281 accagctgcc aagaagtcga taccagtttc aaccattgct ttagcgtctt cgattggagc
    26341 caattcacct ttaccgatga ttccgtcttc ttcaccaccg atagtaccaa cttcagcttc
    26401 tactgagata cctttagcgt gtgctttttc aacaacttct ttagccaatt taaggttttc
    26461 ttcaactgga aggtgtgaac cgtcaaacat gattgaagta taaccaactt cgatacactc
    26521 aagtgcatct tcgtagtgac cgtggtcaag gtggatagct actggtacag tgatacccat
    26581 tgattcaaca aggttagcga tcaagttgcg agcaactttg taaccaccca tgtatttagc
    26641 agcacccatt gaagtttgga tcaaaactgg agctttttta gcttctgctg cgcgcaagat
    26701 agcttgagtc cactcaaggt tgtttgtgtt aaatccacca actgcataac cgttgtcacg
    26761 ggctgcttgg acaaattttt ctgctgaaac gattgccatt ttatcaggcc tcctgtatat
    26821 ttttatgggt catcccattt acattgttca ttttatcact ttttgccaaa aaaatctagt
    26881 ttttcccgca gtttcgattg attttcttct aactccatct atgtaaaccc tttctctccc
    26941 tagtcttggg cgacttttgg aaaagctata aagaaggtta aacgattctc ctccatctcg
    27001 aaacgataag ctaatttttc atgttctaat agactcttaa ccacaaagag ccccatacca
    27061 gaccccttga ccttgcgact ggcattgtca gaaaaagact gggctagttt ttcttgttcc
    27121 tctgagctac agctattttc gataaaaagt tctccttctc tttctccaat tcgaactaag
    27181 ccacctggaa cagagtgctt aatggcattg ctgatgagat tagaaagaat caacttcata
    27241 actgatgggt ttagataagc ctgctgatgg gtcaaactat tgtctatctg gagctctctt
    27301 tccttggcta gcaaggcata atctttgacc agattttgcg tcatctggag gaggtcaatt
    27361 gtttccctat catctcgcaa ttcctgcaca gaagagaggg aaagtatctg cagaacatgg
    27421 tgattgagtt catccacaat ccccaaggca actcccagat actggtctct atccttataa
    27481 cgaccgatat tctctctcat attttcgatt aggattttca aactagccag cggtgttttc
    27541 aattcatgag aagctcctcg taggaattcg accttcatct tctccagctg gagaatggct
    27601 tcattctttt catgcaagtc cgcaataaca gtcaagagat gctggtagag gctattgatt
    27661 tgttccttga gattacctat ctcatcctta gaatccacgc gcaatcgcac ttgggaatcc
    27721 aggtccatca tccgacgggt cacccgcttg atttccaaaa tcggtgcaac aatagtccgg
    27781 gcgtagatgt aggccaccaa gagggaaatc agaaaggagg ccagcaaggt atagggaaga
    27841 aactggagac tgatttgctc cgcttccttt tgtaaatcca tggaagctag aaactggaga
    27901 atcatagtac caccgtcttg cgttttcacc tcgcgctcct caataaagag agaggttgtc
    27961 tggcggtctg tgtccagagg aagactgtcc ttgacttcta acttgtcctc ggtcatctca
    28021 cctttgacgg tccccttgat atcactagtc tgggaataca agtctaacac ttgctcgata
    28081 ctctgcctat ctttcccttc tagggactgg gcaatggctg ttgccttttg accaatggtt
    28141 tcctgacgat gactcagata agtcgaagga aaaagaaaat aaatagctaa atgaaggcag
    28201 ataaccagaa cactaaatat cgagaaggta tagataaata tctttgcaaa taaacctgtt
    28261 cgtttcattt tcgctccaat ttataaccaa cattgcgcac agtgaggata caatccaagt
    28321 ctagcttttt ccgcaattcc ttgatataaa catcaataac acggtcaaag ggaacctcat
    28381 ctgtcgcttt ccagacggca tcgataatct gagaccgagt caaggcccgg ccttcatttt
    28441 tcactagata gtccagaatt tccaactctt tggcattgat aggcacttct tgacctgcga
    28501 ggcttgcact gtagctttca aagtccacct tggtatcctt gtaagaaaag attcgtcctg
    28561 tatcgtagta gcgcttgaaa atcgcgtcca ccctcacttt taagagggag agagagaaag
    28621 gtttttccag atagccatct gccaaagagg caaaggcact catcttgtat tcctcatcct
    28681 gaaaagctgt caacatcaag acaggaacct gactggtttt acgaatctca gctaggactt
    28741 ctaagccgtt aagcttgggc atctggatat ccagtaaaac cagggccacc tcatagctag
    28801 aaaattgctc cagagcttcc tgaccgtccg ctgcctcaat agtttcatag ccacaatccg
    28861 tcaaataatc actgaccccc tcacggatca tctcttcatc ttctacaatt aaaattttca
    28921 tactttaact gctctctatt ttttattttt cttagaataa atacctactc tattttctat
    28981 tatagtctct tgcttatagt ctcttgctgg ccttttgtct gtaagcaact gatcactaga
    29041 taaaacgttg tgaaattcct ttctcataaa ttccataact ttagtatatt atatttaagc
    29101 actaaagtac aaagaaagca actgaaagca atgattttca ccactgcttt cagatttatt
    29161 ttgaattgtt aaatagctat tcctatccac tattcttgaa tagaaacaca agatgcaatc
    29221 tttattccag actcattttt tcaaatttat tcaccatcca gcaagagctc ttttggttgt
    29281 tttctaagga gattgcttga agcaagcgcc ataacgagaa ccactagaac caaggcaagg
    29341 acaaaaatga tgataaagtc tgatgtctga atggaaatgt ctaggctcga caaggtcttg
    29401 ctaaagccat ctacttctgc accgccacca aggttagagg cttgagccgc cttactagcc
    29461 tgtttggcaa cacctgaagt cacattggca aggacagtgt ttccaattgc acgggcagtg
    29521 taattagcta ggaagtaagc agaaactaga gcagggatag caatcaagat agattcggtg
    29581 atgaattgac ccaagatact tgcctgcttg aggccgatag agaggagaat tcccacttcc
    29641 ttgcgacggg cgttgatcca aaggctgagc aagagggcaa ggaggagaac tgagaagctc
    29701 aagctacccc agaagaggag gttggccatc ttgtacatac cagagataga ttgctcaaga
    29761 gctgggtagt tagaggagct cttgacgagt gtgtagctct tccagttgat accactgatg
    29821 ccattcaact ctttcataac atcatccaag ttcttgtctg ctgttacaaa gaaggttgcg
    29881 tccccataaa tggctgtgtc ttctgtgtat ccataaagtt ttgcagcagt gtgaatgtct
    29941 gtaatagctg tgttttcgta aagttcttgt gagtaggtta ctgctgactt attatgacca
    30001 tcaaagagtc ccttgattgt cacttcaact gtttccttgg ctcctttttc attatctgca
    30061 tcgtagatat tagagtccag tttaaccttg tcccctactt tccagccgtg tttggctgcc
    30121 aagtccttgt gcaagaggat tttatccttg tcgtcgttgg ttaagtgctc tccttcgact
    30181 agtttataag aaccagagac aaacttatct tctttagagg agtcattgac acctgtaatc
    30241 atcaagctac ttccaaaacg cttggcacga tcagcagtga gattcttctt ggtttctggc
    30301 gtttcaatca ggtcatatcc agtcaaatct ccgatagcgt tgatacgttt gacataagac
    30361 tcgatggcct tgttttcggt gatttttttg atgtcttcac ccttgatatt cccagcacca
    30421 cgaggcgttc cttggttgac gcgacgattg atttgcatgg agaagctatt ggtgatattt
    30481 ttaaaggtct cctgagaagc cttggcagta gctcccttga ttgacaagcc gaccaaactc
    30541 aagctcgcca tgaggagaat aatcaggaag atgacaatcg atttgaaaaa cttccttgta
    30601 acataggcaa atgcgttgtg taacatagat tccctttcta gattttgttt taatcattct
    30661 atcaaaataa gctcaaatta tttactagta ttgcgcgttt cagtcagttt cttatccttt
    30721 aattcaagtg taatatctga cgcttgtgcc acttctttac tgtgagttac gacaatcaca
    30781 catttacctg ttttctgggc aagtgatttg agtagttcga caatatctcc agcagtttta
    30841 ggatccagat ttcctgttgg ctcatcagct agaataactg gagcttctga gaccaaactg
    30901 cgagcaatgg caacacgttg ctgttgacca cctgataact ggagaacatt ccgcttgatc
    30961 tggctttcat ccaaaccaag ctcaagaagt gtattcttgc ttgccttttt gttgaccaat
    31021 cggatatttt ccagcggaga aagataatct atcaagttat aattttgaaa gaccagggaa
    31081 atatggtgca tgcgatggta agaatagccc ttcttacgaa tatcctctcc ttgaaaaagg
    31141 atagaacctt caacaggact atctagacca gcaagtaggg acaagagtgt ggattttcct
    31201 gctcctgact ccccaataat actgtaaaat tttccgggtt caaaattata atcgatctga
    31261 tataggactg cttcagcagt attcttataa cggtaggtaa catcttgtaa ttgtaataaa
    31321 gtcatgattt ctccttctta actaatagat gataaaattt ctttcggtga ttttctaaat
    31381 aagaatagga aacaaagggc tacagataag caactaagca gaactagaaa aacataggat
    31441 tctgcaaaag ataagatact agttgataaa ctgcttgctt tggctagtgt atcttgtaag
    31501 cttgcctgat ctccacttgc tagtagagtt tggagtaggt aagttgtgat tccgtttcct
    31561 gcaacaaatg ctggaagcaa agctccaaga gataccaaaa ctacctctaa acagaattgt
    31621 aggaagatcg agctcttgcc ttttccaagt gcaagtaaaa tccccacttc atagacccgt
    31681 tctctcaacc agagagacaa aaccagaatt aaggctccag ctcctgctat caacatccca
    31741 taaaggaaga tggtcaggaa ggtttggaaa gttgcaactg agtctttgat ttgttcaaaa
    31801 gccttgtttt ccttttcgac ttggtagcct tgattttcca aggccaagtt ttctacctgc
    31861 ttcatgagtc cgtccatttc cttaggattt tctacataga agcgtgctgc actgacttga
    31921 gcttcactat tgcccaaaag ggtttggcta ctttcatagt ctgtaaagac ttgattttca
    31981 ctgaagtcag aagacaagcc tgtgaatttc tcttgttttt taccagaaaa gatgccgata
    32041 atctcaaact ctactgtttg tccttttcca gattcagact gaccagcatc caagccaatc
    32101 ttgtcatgaa gtgaaagacc gttcttctta gccaattctt cgtggataag gattttcttg
    32161 gaatcccctt tttgaaggtg tcgcccttct tttagattga aagccgaact ggtaaaggtt
    32221 acatccttgg atgaatcctc aagagccgtt aagctaacca agttattgtc tgcagctgat
    32281 aaatcatcac gctccacgct ctgctcgcca gtcactgctt ccttgtcttt tagttttgcg
    32341 accgtctcaa gttcaggaga gacattttcc agccccttaa tcttgcttac agatgctagg
    32401 tctgacaact tgaatgtctg accattctct atcttcttaa tagaaaaaga tgtattgagt
    32461 gatttataaa gattgctttc tactgttttg ttggacttca tcagagtcaa acaggctgaa
    32521 attccggcca ataagaccaa taaaatcaga aataaaataa aacttctcag tcgctttctg
    32581 ctgacataag cccaagatct ttggattgga ttcatttgtc acctccatat ttgtaagact
    32641 attataaaac ccaaatatga aatgtttatg aaatacgaaa aaaaaatatc gagtagggga
    32701 taatctctag cccctctcac accaccgtac gtgccgttcg gcatacggct gttcaactaa
    32761 cttttaacgc atgtcgttca aggtaataat ccaaacacga aaccagtcca cgtttttcaa
    32821 ggactggttt tgatatagca cgtttaagta ccgacttctg agctactata gtagattgaa
    32881 actagaataa tatacctcta cttctaaaat attgttagaa atcgatttga cttccctgat
    32941 cgattcgtcc tattcttatt tcattttaat ataattgata gtggtcgccc cagccagata
    33001 ccttatctgc tatccattta ggaaccccta acttaagcaa tccccataat cgtctcgatt
    33061 tcttcttcca ttgcttccag ataatcactc gtaggcgagt acgcaagcgc tcatctatgc
    33121 tagtgactat acttttcata tttataattc attcctttcg tttcactcaa ggcacaacac
    33181 agaatgaaaa agtgttgtga tctttatttt gttttataat aatagtgaga aagcctatca
    33241 ctactacaaa tcacggggag gtgaataagt gagtggtaca gccactacct cgcatatttt
    33301 gtcacatcat ttaacggtac ataataagtt gtaccatctg aataagttgc tacaatatca
    33361 tttgcatgct ctccttcacc tttagcaaag gttggagctc ctgctggatg atttttattt
    33421 gcctctttca atttttcaat aatggcattt ttttctgtat cttttatatt atcaggattt
    33481 ttcactaaga ttttgtctgg atatgtcggt ttagcagaaa caatttttac tgttacttct
    33541 tttttattcg aagcacttgt ccagtttcca gcattatctt tagcatttaa ttttacagta
    33601 attcctgaac taggaacttc agtagcaggt tgattatcaa cattattcaa ctttaatttc
    33661 aaaagagctg ttgcatcaga cgttttatca atcgttatat ataatgatga attgttatta
    33721 taaccagttc cttcatattt agctgtttgt gagctacttg aaacagaact gaaattatgc
    33781 ccactacctc cctgattatc ttcaatgctt acgtctaaat gaacttcccc actattattt
    33841 ggcttagcaa caactgttat agtaaaataa cataaaattt gcataaatag attagggaaa
    33901 tcaaagtaac ttctaggaat gttttatact cttcgaaaat caaattcaaa ccacgtcagc
    33961 ttcaccttga cgtactcaag tacagcctgc ggctagcttc ctagtttgca ctttgatttt
    34021 cattgagtat tagcagtcac agtgtacttt cccagcatca agtcactata actctgcaca
    34081 taaaaatgga gaagatggcc atcctcttct ccaaatatta acg
//
LOCUS       DBEJHE010000022        33292 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC4 isolate 671759
            SAMN38261586-rid24793303.denovo.22, whole genome shotgun sequence.
ACCESSION   DBEJHE010000022 DBEJHE010000000
VERSION     DBEJHE010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261586
            Sequence Read Archive: SRR26833752
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 33292)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33292)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576136.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576136.1
            Genome Coverage       :: 109x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 19:48:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,067
            CDSs (total)                      :: 2,029
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 131
            CDSs (without protein)            :: 131
            Pseudo Genes (ambiguous residues) :: 0 of 131
            Pseudo Genes (frameshifted)       :: 64 of 131
            Pseudo Genes (incomplete)         :: 59 of 131
            Pseudo Genes (internal stop)      :: 46 of 131
            Pseudo Genes (multiple problems)  :: 32 of 131
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33292
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261586-rid24793303.denovo.22"
                     /strain="GPSC4"
                     /isolate="671759"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(<1..66)
                     /locus_tag="ACL3EZ_001390"
     CDS             complement(<1..66)
                     /locus_tag="ACL3EZ_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HGR0392947.1"
                     /translation="MATNKRYYWIKLKEEFFTDKRI"
     gene            complement(193..720)
                     /locus_tag="ACL3EZ_001391"
     CDS             complement(193..720)
                     /locus_tag="ACL3EZ_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008902124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PcfB family protein"
                     /protein_id="HGR0392948.1"
                     /translation="MINEEISKEAGQAAQTIISYTIKATKESINLEKEIRKKMNETLE
                     KANGNLKSLMGDEMKIKDLYKKGQLENISIDQIDLKDLKKELNKLGVSFSVMKNKESK
                     NYEIFFQAKDIKVMEYAFKQVIAKENKKEKESILKQIKKYKDLSKNKDKTKEKGKRKV
                     KEKVKPNKKDMTREI"
     gene            complement(906..1079)
                     /locus_tag="ACL3EZ_001392"
     CDS             complement(906..1079)
                     /locus_tag="ACL3EZ_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019118552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0392949.1"
                     /translation="MNKRQELIDELIKANEDGTYKTYKSTEEIKAMNNEEIQIIYSNM
                     KNYLSDKRTHINY"
     gene            complement(1153..2793)
                     /gene="mobQ"
                     /locus_tag="ACL3EZ_001393"
                     /pseudo
     CDS             complement(1153..2793)
                     /gene="mobQ"
                     /locus_tag="ACL3EZ_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019213953.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MobQ family relaxase"
     gene            complement(3107..3424)
                     /locus_tag="ACL3EZ_001394"
     CDS             complement(3107..3424)
                     /locus_tag="ACL3EZ_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000968321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3847 domain-containing protein"
                     /protein_id="HGR0392950.1"
                     /translation="MMASKRLSIEEQIEKKEESIKQLQNQKRQLKKKLNEQERKARNK
                     RLIEKGAVFESIFEESIDLTKDEFYKLIKTLNDEEIRLNIMEILEERIDDNVEKSSKD
                     EIT"
     gene            complement(3480..3959)
                     /locus_tag="ACL3EZ_001395"
     CDS             complement(3480..3959)
                     /locus_tag="ACL3EZ_001395"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: protein motif:HMM:NF013579.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HGR0392951.1"
                     /translation="MFITEKKGKSSQVPTGSSIPKRYLLDGKTPRISVTNIDNGILGY
                     YEDIDDKNYRVFENFISVSFLGAVFYHKYKASLDMKIHCLKLKNKELNKEVAFYLTSI
                     IRQALKNTEYKDQISSTVLPDIKIKLPIDSRGTPDWNYMERYIEDLKLKCNIANYNI"
     gene            complement(3958..4142)
                     /locus_tag="ACL3EZ_001396"
                     /pseudo
     CDS             complement(3958..4142)
                     /locus_tag="ACL3EZ_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612340.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(4293..5087)
                     /locus_tag="ACL3EZ_001397"
     CDS             complement(4293..5087)
                     /locus_tag="ACL3EZ_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000677523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0392952.1"
                     /translation="MKGLWSNNLTCGYDEKIILENINIKIPEEKISVIIGSNGCGKST
                     LIKTLSRLIKPLEGEVLLDNKSINSYKEKDLAKHIAILPQSPIIPESITVADLVSRGR
                     FPYRKPFKSLGKDDLEIINRSMVKANVEDLANNLVEELSGGQRQRVWIALALAQDTSI
                     LLLDEPTTYLDISYQIELLDLLTDLNQKYKTTICMILHDINLTARYADYLFAIKEGKL
                     VAEGKPEDILNDKLVKDIFNLEAKIIRDPISNSPLMIPIGKHHVSS"
     gene            complement(5087..6094)
                     /locus_tag="ACL3EZ_001398"
     CDS             complement(5087..6094)
                     /locus_tag="ACL3EZ_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HGR0392953.1"
                     /translation="MQNLIIGIQKRKNRITLFSSLFLLIIISLSFFILLIGDESYSFS
                     TLIKVLNSETVPGASFSIMEIRLPKLLAGIIAGWSFGLAGFIFQTMLRNPLASPDIIG
                     VTSSSSIAAVFCILVLKTNSLTTGIISITCGLTSSLILFLLAKKDGFSAARLIILGIG
                     FQAVTRAGTSFLLLKVARYELQEVMRWLSGSLSFTKLDDIPLVLIVSIIATILVLFFN
                     KRLEIIELGEEIAIGLGANPELSRLVLIFCAVSLTAFSTSITGPIACISFLAGPIALN
                     IGKKRSPILAGLVGILLVLLSDIFSQNILPARYPVGVVTGLLGSPYLIYLLIKMNRRN
                     I"
     gene            complement(6094..7101)
                     /locus_tag="ACL3EZ_001399"
     CDS             complement(6094..7101)
                     /locus_tag="ACL3EZ_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FecCD family ABC transporter permease"
                     /protein_id="HGR0392954.1"
                     /translation="MRNKKQINLGIIFVICLGLLITIFLSLKLGTKEINIRDFLAAFG
                     MGNTNDDFIKSIIYKRIPRTIFAILAGSSLAISGVLMQSVTRNPIADPGILGINTGAS
                     LSVVIGLSFLGISSSISHISFAIIGGLVSAIFVYAIAVSGKAGLTPIKLALSGTCVSM
                     ALSSFVSFLILPNNNVLDKFRFWQIGSLGAATLSSISTLLPFIILGHLIAIFISSDLN
                     ALAMGDEMAVGLGVNVNRIRSLAIIASVLLCSSITAIGGPIGFVGLIVPHFCGLFISK
                     DIRTMTISSSFIGAELLLICDIIGRMLGKPGEIEVGIITAIIGGPVLIYVTMKNRGVN
                     N"
     gene            complement(7091..8116)
                     /locus_tag="ACL3EZ_001400"
     CDS             complement(7091..8116)
                     /locus_tag="ACL3EZ_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015891 - siderophore transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron-siderophore ABC transporter
                     substrate-binding protein"
                     /protein_id="HGR0392955.1"
                     /translation="MKNKFFLIAILAMCIVFSACSSNSVKNEENTSKEHAPDKIVLDH
                     AFGQTILDKKPERVATIAWGNHDVALALGIVPVGFSKANYGVSADKGVLPWTEEKIKE
                     LNGKANLFDDLDGLNFEAISNSKPDVILAGYSGITKEDYDTLSKIAPVAAYKSKPWQT
                     LWRDMIKIDSKALGMEKEGDELIKNTEARISKELEKHPEIKGKIKGKKVLFTMINAAD
                     TSKFWIYTSKDPRANYLTDLGLVFPESLKEFESEDSFAKEISAEEANKINDADVIITY
                     GDDKTLEALQKDPLLGKINAIKNGAVAVIPDNTPLAASCTPTPLSINYTIEEYLNLLG
                     NACKNAK"
     gene            complement(8509..8727)
                     /locus_tag="ACL3EZ_001401"
     CDS             complement(8509..8727)
                     /locus_tag="ACL3EZ_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001207345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGR0392956.1"
                     /translation="MALNYKPLWIQLAKKGLKKTDVIAMAGLTTNVMAQMGKDKPITF
                     KNLERICKALSCTPNDIISFEDNFSDEE"
     gene            complement(9018..9251)
                     /locus_tag="ACL3EZ_001402"
     CDS             complement(9018..9251)
                     /locus_tag="ACL3EZ_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit M"
                     /protein_id="HGR0392957.1"
                     /translation="MKKDKEVYDKVCEYLSPHLNKDMEVLELACWFRVITVIEANSYV
                     NIRSSRLLPKFKTQKINSWCAAYSIHFNNGYCN"
     gene            complement(9465..11096)
                     /gene="rlmD"
                     /locus_tag="ACL3EZ_001403"
     CDS             complement(9465..11096)
                     /gene="rlmD"
                     /locus_tag="ACL3EZ_001403"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000914584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HGR0392958.1"
                     /translation="MLKKNDIVEVEIVDLTHEGAGVAKVDGLVFFVENALPSEKILMR
                     VLKVNKKIGFGKVEKYLVQSPHRNQDLDLAYLRSGIADLGHLSYPEQLKFKTKQVKDS
                     LYKIAGIADVEVAETLGMEHPVKYRNKAQVPVRRVNGVLETGFFRKNSHNLMLLEDFF
                     IQDPVIDQVVVALRDLFRRFDLKPYDEKEHSGLIRNLVVRRGHYSGQIMVVLVTTRPK
                     VFRVDQLIEQVIKQFPEIVSVMQNINDQNTNAIFGKEWRTLYGQDYITDQMLGNDFQI
                     AGPAFYQVNTEMAEKLYQTAIDFAELKKDDVVIDAYSGIGTIGLSVAKHVKEVYGVEL
                     IPEAVENSKKNAQLNNISNAHYVCDTAENAMKNWLKDGIQPTVILVDPPRKGLTESFI
                     KASAQTGADRIAYISCNVATMARDIKLYQELGYELKKVQPVDLFPQTHHVETVALLSK
                     LDVDKHISVEIELDEMDLTSAESKATYAQIKEYVWNKFELKVSTLYIAQIKKKCGIEL
                     REHYNKSKKDKQIIPQCTPEKEEAIMDALRHFKMI"
     gene            complement(11170..12144)
                     /locus_tag="ACL3EZ_001404"
     CDS             complement(11170..12144)
                     /locus_tag="ACL3EZ_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HGR0392959.1"
                     /translation="MRKKLFLTGAAVLWAVTAMNSAHAATDVQKVIDETYVQPEYVLG
                     SSLSEDQKNQTLKKLGYNASTDTKELKTMTPDVYSKIMNVANDSSLQLYSSAKIQKLG
                     DKSPLEVKIETPENITKVTQDMYRNAAVTLGMEHAKITVAAPIPVTGESALAGIYYSL
                     EANGAKVPQANKDLAQEELKALSDINAENKDKSGYDANKLNVALADIKSGLAKAKESK
                     GNLTEEDVRKIVEDTLKNYKLDQVITGNQINIIINFALNLSKSDILSNADFTKTLNDL
                     KQSIVSQAGDSFKNINLNFDADKALEDGGNFLSSLWQALVNFFKSFGS"
     gene            complement(12218..12832)
                     /gene="pmp23"
                     /locus_tag="ACL3EZ_001405"
     CDS             complement(12218..12832)
                     /gene="pmp23"
                     /locus_tag="ACL3EZ_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000476388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase Pmp23"
                     /protein_id="HGR0392960.1"
                     /translation="MFKRIRRVLVLAVFLFAGYKAYRVHQDVKQVMTYQPMVREILSE
                     KDTPANEELVLAMIYTETKGKEGDVMQSSESASGSTNTINDNASSIRQGIQTLTGNLY
                     LAQKKGVDIWTAVQAYNFGPAYIDFIAQNGKENTLALAKQYSRETVAPLLGNRTGKTY
                     SYIHPISIFHGAELYVNGGNYYYSRQVRLNLYIIKCFTLFSTSG"
     gene            complement(12832..13806)
                     /locus_tag="ACL3EZ_001406"
     CDS             complement(12832..13806)
                     /locus_tag="ACL3EZ_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HGR0392961.1"
                     /translation="MDIYIKKAIIHQFSPDDTELFLADKFLNITPKIEEYLRKKIEHV
                     YSDEAKTGIFEEENPFFNHITDDLLETSVTLANLWKEEFSISENLKTNDLIFVQFSKE
                     GVEHFAFLRIALRETLTHLGGEVDNPIKLTQNNLPGFGTGADEALVVNLQSRKYHLIE
                     KRIKYNGTFLNYFSDNLLAVAPKISPKKSIKELEKTAQRIAESFNTDDFQFQSKVKSA
                     IFNNLEESNELSPEKLANDLFDNNLTARLSFIDQVKEAVPEPVQFDEIDASRQLKKFE
                     NQKLSLSNGIELIVPNNVYQDAESVEFIQNENGTYSILIKNIEDIQSK"
     gene            complement(13814..15070)
                     /gene="glyA"
                     /locus_tag="ACL3EZ_001407"
     CDS             complement(13814..15070)
                     /gene="glyA"
                     /locus_tag="ACL3EZ_001407"
                     /EC_number="2.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004372 - glycine hydroxymethyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0070905 - serine binding [Evidence IEA];
                     GO_process: GO:0019264 - glycine biosynthetic process from
                     serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HGR0392962.1"
                     /translation="MIFDKDDFKAYDADLWNAIAKEEERQQNNIELIASENVVSKAVM
                     AAQGSILTNKYAEGYPGRRYYGGTDVVDVVETLAIERAKEIFGAKFANVQPHSGSQAN
                     CAAYMSLIEPGDTVMGMDLASGGHLTHGAPVSFSGQTYNFVSYSVDPETELLDFDAIL
                     KQAQEVKPKLIVAGASAYSQIIDFSKFREIADAVGAKLMVDMAHIAGLVAAGLHPSPV
                     PYAHITTTTTHKTLRGPRGGLILTNDEELAKKINSAIFPGIQGGPLEHVVAAKAVSFK
                     EVLDPAFKEYAANVIKNSKAMADVFLQDPDFRIISGGTENHLFLVDVTKVVENGKVAQ
                     NLLDEVNITLNKNSIPYETLSPFKTSGIRIGAAAITARGFGEEESRKVAELIIKTLKN
                     SENEAVLEEVRSAVKELTDAFPLYED"
     gene            complement(15132..15563)
                     /locus_tag="ACL3EZ_001408"
     CDS             complement(15132..15563)
                     /locus_tag="ACL3EZ_001408"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000942930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR0392963.1"
                     /translation="MLRDLQETDVKAICDINQEALGYTFSPEETASQLARLSQDSHHF
                     LLGYEDAANHVLLGYVHAEVYESLYSKAGFNILALAVSPQAQGQGIGKSLLQGLEEEA
                     KRCGYGFIRLNSANHRLGAHAFYEKVGYTCDKMQKRFIRIF"
     gene            complement(15565..16167)
                     /locus_tag="ACL3EZ_001409"
     CDS             complement(15565..16167)
                     /locus_tag="ACL3EZ_001409"
                     /EC_number="2.7.7.87"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003725 - double-stranded RNA binding
                     [Evidence IEA];
                     GO_function: GO:0061710 - L-threonylcarbamoyladenylate
                     synthase [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonylcarbamoyladenylate synthase"
                     /protein_id="HGR0392964.1"
                     /translation="MMDRIRQELENGGAVVLPTETVYGLFAKALDEKAVDHVYQLKRR
                     PRDKALNLNIASFEDILHFSKNQPTYLQKLVETFLPGPLTIILEANDRVPYWVNSDLA
                     TIGFRMPSHPITLDLIRETGPLIGPSANISGQASGVTFEQILKDFDQEVLGLEDDAFL
                     TGQDSTIVDLSGDKVKILRQGAIKREDILARLPEISFEEA"
     gene            complement(16151..16990)
                     /gene="prmC"
                     /locus_tag="ACL3EZ_001410"
     CDS             complement(16151..16990)
                     /gene="prmC"
                     /locus_tag="ACL3EZ_001410"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0018364 - peptidyl-glutamine methylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HGR0392965.1"
                     /translation="MKLAQLFSNFEEELIRQGEEAESLSFVYRSLKNLSFTDFIFALQ
                     QEVTTEEEKQFVEDIYQQLAAHKPAQYIIGQADFYGMHLKVDERVLIPRPETEELVEL
                     ILTENLETNLSVLDIGTGSGAIALALAKNRPDWSVTAADVSQEALELASENASDQNLN
                     IFFKKSDCFAEISEKYDIIVSNPPYISREDESEVGLNVLHSEPHLALFADEDGLAIYC
                     RIAEDAKDYLKDGGKIYLEIGYKQGQSVPELFRKHLPEKKVRTLKDQFGQNRMVVVDD
                     GQD"
     gene            complement(16990..18069)
                     /gene="prfA"
                     /locus_tag="ACL3EZ_001411"
     CDS             complement(16990..18069)
                     /gene="prfA"
                     /locus_tag="ACL3EZ_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003747 - translation release factor
                     activity [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HGR0392966.1"
                     /translation="MNIYDQLQAVEDRYEELGELLSDPDVVSDTKRFMELSKEEASNR
                     DTVIAYREYKQVLQNIVDAEEMIKESGGDADLEEMAKQELKDAKAEKEEYEEKLKILL
                     LPKDPNDDKNIILEIRGAAGGDEAALFAGDLLTMYQKYAEAQGWRFEVMEASMNGVGG
                     FKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDI
                     DPKDLRVDIYHASGAGGQNVNKVATAVRIVHLPTNIKVEMQEERTQQKNREKAMKIIR
                     ARVADHFAQIAQDEQDAERKSTIGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTIL
                     SGKLDEVVDALVLYDQTQKLEELNK"
     gene            complement(18066..18656)
                     /locus_tag="ACL3EZ_001412"
     CDS             complement(18066..18656)
                     /locus_tag="ACL3EZ_001412"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000068157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004797 - thymidine kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HGR0392967.1"
                     /translation="MAQLYYRYGTMNSGKTIEILKVAYNYEEQGKGVVIMTSALDTRD
                     GVGYVSSRIGMKRPALAIEETTDIFGYIRDLPEKPYCVLVDEAQFLKRHHVYDLARVV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLLADKIDEIKTICQYCKKKATMVLRTQDGL
                     PVYDGEQIQIGGNETYISVCRKHYFAPEINKENEEK"
     gene            18779..18961
                     /locus_tag="ACL3EZ_001413"
     CDS             18779..18961
                     /locus_tag="ACL3EZ_001413"
                     /EC_number="5.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005589823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HGR0392968.1"
                     /translation="MPFVRIDLFEGRTLEQKKALAKEVTEAVVRNTGAPQSAVHVIIN
                     DMPEGTYFPQGEMRTK"
     gene            19097..20470
                     /gene="mnmE"
                     /locus_tag="ACL3EZ_001414"
     CDS             19097..20470
                     /gene="mnmE"
                     /locus_tag="ACL3EZ_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002906470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HGR0392969.1"
                     /translation="MITREFDTIAAISTPLGEGAIGIVRLSGTDSFAIVQKIFKGKDL
                     NKVASHTLNYGHIIDPLTGKVMDEVMVGAMKSPKTFTREDIIEINTHGGIAVTNEILQ
                     LAIREGARLAEPGEFTKRAFLNGRVDLTQAEAVMDIIRAKTDKAMNIAVKQLDGSLSD
                     LINNTRQEILNTLAQVEVNIDYPEYDDVEEATTAVVREKTMEFEQLLTNLLRTARRGK
                     ILREGISTAIIGRPNVGKSSLLNNLLREDKAIVTDIAGTTRDVIEEYVNINGVPLKLI
                     DTAGIRETDDIVEQIGVERSKKALKEADLVLLVLNASEQLTAQDRQLLEISQDTNRII
                     LLNKTDLPETIETSKLPEDVIRISVLKNQNIDKIEERINNLFFENAGLVEQDATYLSN
                     ARHISLIEKAVESLQAVNQGLELGMPVDLLQVDLTRTWEILGEITGDAAPDELITQLF
                     SQFCLGK"
     gene            complement(20517..21452)
                     /gene="dapA"
                     /locus_tag="ACL3EZ_001415"
     CDS             complement(20517..21452)
                     /gene="dapA"
                     /locus_tag="ACL3EZ_001415"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008840 - 4-hydroxy-tetrahydrodipicolinate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HGR0392970.1"
                     /translation="MSYQDLKECKIITAFITPFHEDGSINFDAIPALIEHLLAHHTDG
                     ILLAGTTAESPTLTHDEELELFAAVQKVVNGRVPLIAGVGTNDTRDSIEFVKEVAEFG
                     GFAAGLAIVPYYNKPSQEGMYQHFKAIADASDLPIIIYNIPGRVVVELTPETMLRLAD
                     HPNIIGVKECTSLANMAYLIEHKPEEFLIYTGEDGDAFHAMNLGADGVISVASHTNGD
                     EMHEMFTAIAESDMKKAAAIQRKFIPKVNALFSYPSPAPVKAILNYMGFEAGPTRLPL
                     VPAPEEDAKRIIKVVVDGDYEATKATVTGVLRPDY"
     gene            complement(21508..22584)
                     /locus_tag="ACL3EZ_001416"
     CDS             complement(21508..22584)
                     /locus_tag="ACL3EZ_001416"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000542485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004073 - aspartate-semialdehyde
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HGR0392971.1"
                     /translation="MGYTVAVVGATGAVGAQMIKMLEESTLPIDKIRYLASARSAGKS
                     LKFKDQDITIEETTETAFEGVDIALFSAGGSTSAKYAPYAVKAGVVVVDNTSYFRQNP
                     DVPLVVPEVNAHALDAHNGIIACPNCSTIQMMVALEPVRQKWGLDRIIVSTYQAVSGA
                     GMGAILETQRELREVLNDGVKPRDLHAEILPSGGDKKHYPIAFNALPQIDVFTDNDYT
                     YEEMKMTKETKKIMEDDSIAVSATCVRIPVLSAHSESVYVETKEVAPIEEVKAAIASF
                     PGAVLEDDVVHQIYPQAINAVGSRDTFVGRIRKDLDAEKGIHMWVVSDNLLKGAAWNS
                     VQIAETLHERGLVRPTAELKFELK"
     gene            complement(23170..23242)
                     /locus_tag="ACL3EZ_001417"
     tRNA            complement(23170..23242)
                     /locus_tag="ACL3EZ_001417"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(23207..23209),aa:Thr,seq:ggt)
     gene            complement(23342..23851)
                     /locus_tag="ACL3EZ_001418"
     CDS             complement(23342..23851)
                     /locus_tag="ACL3EZ_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HGR0392972.1"
                     /translation="MKKLTIRDVADIAIVAAIYVVLTVTPPLNAISYGAYQFRISEMM
                     NFMAFYNPKYIIGVTIGCMIANFFSFGLLDVFVGGGSTLVFLSLGVWLFAKYSKDYLF
                     NGLIRKDHFFFSILFSISMFTIAAELNIVAELPFFLTWFTTGIGEFASLIIGAIIIGK
                     IGRRIDLSK"
     regulatory      complement(23849..23945)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01054"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="PreQ1 riboswitch class II; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF01054"
     gene            23974..24405
                     /locus_tag="ACL3EZ_001419"
     CDS             23974..24405
                     /locus_tag="ACL3EZ_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HGR0392973.1"
                     /translation="MKKPIQKFFNNEILAYLFFGLATTLVSILSRLVIYQLSHQELLA
                     TALANIIGILFAFITNDTIVFKQKKKNRLIRLVKFSLARLSTFLLDLFLTFLFVTQFP
                     HIIGQFVTENIDKINAIETIIAQIFIIIINYILSKVYIFRK"
     gene            24487..24864
                     /gene="mscL"
                     /locus_tag="ACL3EZ_001420"
     CDS             24487..24864
                     /gene="mscL"
                     /locus_tag="ACL3EZ_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008381 - mechanosensitive monoatomic ion
                     channel activity [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HGR0392974.1"
                     /translation="MLKNLKSFLLRGNVIDLAVGVVIASAFGAIVTSLVNDIITPLIL
                     NPALKAAKVERIAQLSWHGVGYGNFLSAIINFIFVGTALFFIIKGIEKAQKLTGIKKE
                     KTAEKKPTELEVLQEIKALLEKK"
     gene            complement(24906..26000)
                     /gene="hemH"
                     /locus_tag="ACL3EZ_001421"
     CDS             complement(24906..26000)
                     /gene="hemH"
                     /locus_tag="ACL3EZ_001421"
                     /EC_number="4.98.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004325 - ferrochelatase activity
                     [Evidence IEA];
                     GO_process: GO:0006779 - porphyrin-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferrochelatase"
                     /protein_id="HGR0392975.1"
                     /translation="MKKAILMMTFGSPEEITFEGVADFFTNIRRGVRPQDHEIQTLYD
                     NYVRIGGTPLQKITRQEVALVEARLGNEYSVYFANKFSSPFIPDVIGQMEADGIEQCI
                     CLILEPHYSFYSVMGYEKFLESKQIQFLVIKDWYQEEALLNYWADEIAKILKEEVKQD
                     SFKVIFSAHSVPIFALDFGDPYIDQIFENSKLVAEKLGLSSEQYTNTWQSESDIGIPW
                     IKPDVLEYLREQTEHPDHYIFVPISFISEHIEVLFDNDVECYDLCQEFGVNYHRPPMP
                     NTDSRLIDALVNTVRVNENQEFKEFLPEEETFDELVPSDETKNILAESEDLQMPEFVK
                     KLIEKKGRENVKMPYLIKKMLEKAGKLPKE"
     gene            26155..27378
                     /gene="pepT"
                     /locus_tag="ACL3EZ_001422"
     CDS             26155..27378
                     /gene="pepT"
                     /locus_tag="ACL3EZ_001422"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000222045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0045148 - tripeptide aminopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HGR0392976.1"
                     /translation="MTYPNLLDRFLTYVKVNTRSDEHSTTTPSTQSQVDFATNVLIPE
                     MKRVGLQNVYYLPNGFAIGTLPANDPSLTRKIGFISHMDTADFNAEGVNPQVIENYDG
                     GVIELGNSGFKLDPADFKSLEKYPGQTLITTDGTSLLGADDKSGIAEIMTAIEYLTAH
                     PEIKHCEIRVGFGPDEEIGVGANKFDAEDFDVDFAYTVDGGPLGELQYETFSAAGAEL
                     HFQGRNVHPGTAKEQMVNALQLAIDFHNQLPENDRPELTEGYQGFYHLMDVTGSVEEV
                     RASYIIRDFEKDAFEARKASMQSIADKMNAELGSYRVTLNLTDQYYNMKEVIEKDMTP
                     ITIAKAVMEDLGITPIIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEYVSLQTM
                     ERAVDTIIGIVAYKG"
     gene            complement(27414..28067)
                     /locus_tag="ACL3EZ_001423"
                     /pseudo
     CDS             complement(27414..28067)
                     /locus_tag="ACL3EZ_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672614.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family hydrolase"
     gene            28065..28229
                     /locus_tag="ACL3EZ_001424"
                     /pseudo
     CDS             28065..28229
                     /locus_tag="ACL3EZ_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057566.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            complement(28500..29511)
                     /locus_tag="ACL3EZ_001425"
                     /pseudo
     CDS             complement(28500..29511)
                     /locus_tag="ACL3EZ_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669441.1,RefSeq:WP_007521835.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
     gene            complement(29737..32856)
                     /gene="phtE"
                     /locus_tag="ACL3EZ_001426"
     CDS             complement(29737..32856)
                     /gene="phtE"
                     /locus_tag="ACL3EZ_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtE"
                     /protein_id="HGR0392977.1"
                     /translation="MKFSKKYIAAGSAVIVSLSLCAYALNQHRSQENKDNNRVSYVDG
                     SQSSQKSENLTPDQVSQKEGIQAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDALFSE
                     ELLMKDPNYQLKDADIVNEVKGGYIIKVDGKYYVYLKDAAHADNVRTKDEINRQKQEH
                     VKDNEKVNSNVAVARSQGRYTTNDGYVFNPADIIEDTGNAYIVPHGGHYHYIPKSDLS
                     ASELAAAKAHLVGKNMQPSQLSYSSTASDNNTQSVAKGSTSKPANKSENLQSLLKELY
                     DSPSAQRYSESDGLVFDPAKIISRTPNGVAIPHGDHYHFIPYSKLSALEEKIARMVPI
                     SGTGSTVSTNAKPNEVVSSLGSLSSNPSSLTTSKELSSASDGYIFNPKDIVEETATAY
                     IVRHGDHFHYIPKSNQIGQPTLPNNSLATPSPSLPINPGTSHEKHEEDGYGFDANRII
                     SEDESGFVMSHGDHNHYFFKKDLTEEQIKAAQKHLEEVKTSHNGLDSLSSHEQDYPSN
                     AKEMKDLDKKIEEKIAGIMKQYGVKRESIVVNKEKNAIIYPHGDHHHADPIDEHKPVG
                     IGHSHSNYELFKPEEGVAKKEGNKVYTGEELTNVVNLLKNSTFNNQNFTLANGQKRVS
                     FSFPPELEKKLGINMLVKLITPDGKVLEKVSGKVFGEGVGNIANFELDQPYLPGQTFK
                     YTIASKDYPEVSYDGTFTVPTSLAYKMASQTIFYPFHAGDTYLRVNPQFAVPKGTDAL
                     VRVFDEFHGNAYLENNYKVGEIKLPIPKLNQGTTRTAGNKIPVTFMANAYLDNQSTYI
                     VEVPILEKENQTDKPSILPQFKRNKAQENSKLDEKVEEPKTSEKVEKEKLSETGNSTS
                     NSTLEEVPTVDPVQEKVAKFAESYGMKLENVLFNMDGTIELYLPSGEVIKKNMADFTG
                     EAPQGNGENKPSENGKVSTGTVENQPTENKPADSLPEAPNKKPVKPENSTDNGMLNPE
                     GNVGSDPMLDPALEEAPAVDPVQEKLEKFTASYGLGLDSVIFNMDGTIELRLPSGEVI
                     KKNLSDLIA"
     gene            complement(33066..>33292)
                     /locus_tag="ACL3EZ_001427"
     CDS             complement(33066..>33292)
                     /locus_tag="ACL3EZ_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0392978.1"
                     /translation="EIPQVENSVINAKIAEAEALLEKVTDSSIRQNAMETLTGLKSSL
                     LLGTKDNNTISAEVDSLLALLKKSQPAPIQ"
BASE COUNT         9462 a         6519 c         5651 g        11660 t
ORIGIN      
        1 tatccttttg tctgtgaaaa attcttcttt taattttatc caatagtatc ttttgtttgt
       61 tgccatatct gctcctttct tgattttcga taatcgaaat tcttgatttc cgattttcgg
      121 aattctggac ttctgttttt cggaagtctt gttattatgg ttatttaagg gtgtaacttt
      181 tcgttactcc ctttagattt ctctggtcat atcttttttg tttggtttta ctttttcttt
      241 tactttcctt tttccttttt cttttgtctt atctttgttt ttggataggt ctttgtattt
      301 ctttatttgt tttaggatac tttctttttc ttttttattt tccttggcta tgacttgctt
      361 aaaggcatat tccattactt ttatgtcttt ggcttggaag aatatttcat agtttttgct
      421 ttctttgttt ttcattactg agaaacttac tccaagtttg tttagttctt tttttaagtc
      481 tttgaggtcg atttgatcta tgcttatatt ttctagttgt cctttcttgt agagatcttt
      541 tattttcatt tcatcgccca taagactttt taagtttcca tttgcttttt ctaaagtttc
      601 attcatcttt tttcttattt ctttttctaa attgattgat tcttttgttg cctttattgt
      661 gtatgatatt atggtttgtg ctgcttgacc tgcttccttg cttatttctt cgtttatcat
      721 gcttttctct cctttgtttg aattaaaaaa gggaagtata ggttttaatt tttctatact
      781 tccctttgct tgtttttatt ttattgttct tggtggtgga atactttatt ttgatgtttt
      841 tatatatttc ttaggtcttt gtacctttta tacttttaaa aatagcttac actacctttc
      901 cacctttaat agtttatgtg tgttcttttg tctgatagat agtttttcat gttggaatat
      961 ataatctgta tttcttcatt gttcattgct tttatttctt ctgtgctttt ataggttttg
     1021 tatgttccat cttcatttgc ttttatgagt tcatctatta gctcttgcct tttattcatc
     1081 tctattacct cctagatctg actttagttg tttggtcata ttatagcttg gataagatat
     1141 ttttaccagg tcttatcttt cttgatccat tttcttgttt ttcatcattt ctctgtattc
     1201 attatcttta ttaacttggt cttggaactt tttaatctgt gctattacac ttggtttttc
     1261 tccctgtttt attagcttat ctatttctat ggataaatct ataccaagtt ctttgtttac
     1321 aaaatctact gaatatttta tatgattaat ttcctggtat tcatctttta tcttgtcttt
     1381 ttctttattt atttcttcaa gattttacat taaaagaatt ttttcttcat tccacttttt
     1441 aggacttagt ttttccttat ctgataggag tttttttaat ttcccactta ctaatttata
     1501 ttggtctata tctttcttat gtttgttata aaatgcttct tttgtgaata tatttttctt
     1561 ttgatattct tcataaactt cttttttggc tttgtagatt tcatagtata gaattttctt
     1621 ttctacatct tccatttctt tatggattgt ctttgctttt ttatttagcc tataactatt
     1681 agactttaaa gtttctattt ttgtttgtaa ctgacctatg gtttctatgt tgttttttct
     1741 taaataacta tatgcacttg ttagcttttt gaagtcatat ttttctttat tagtttttgc
     1801 atatcctttt agatatttac ttttttcttt ttgaatttct gaataagtta atagataatt
     1861 tgttagatta aaaagtttag ggttgtctat taccttatct ctttcgatat ccttaaattt
     1921 ttcataagca gtagataagt tatctaataa atttcctatc caacccttta atgtttttat
     1981 ctcttctttt attgttttta caagttgatt atattttctt atttctctat tatagtttcc
     2041 cttgtcagtt tctattccct ttctttccat tgcacttgct gctgatccta aatggattgt
     2101 cggtagataa tctgaatttt gtcttttaaa actcctatgg tctactcttt tttctgctcc
     2161 tgctctttct aaatatttgt tacaaagatc tgaaaaattt tctctccatt gttctacatt
     2221 gcctgtatcg ttccaggttg ttagttctac ttttcttgtc tttggttttc catttttgtt
     2281 taatactttt tctccttttt catctaggat atattctttt tttgacttgg ctaagaactc
     2341 tcctttttcg tttattggtc gcattatggt cattatatga caatggatat ttccattttt
     2401 atcttgactc tcatcatgaa ttgcataatc tactatcatt ccttgtgatg ttaaattttc
     2461 ttttatatat ctttcaacca ggtttttatt ttcacttaaa gataactctt ttggtagtcc
     2521 tattatgaat tgtcttgcta gttgtgcatt agaatttttt tctgccattt ctactttatt
     2581 ccataaggta gacctatcat taaattcttt tggtatatga tcaggcaata ttatattttt
     2641 tactaatatt ttttcttttc ttgtgtagtc atgggttact ccgtcccatt cattttttat
     2701 tttttctcca cttatatatg ctgcacttgc tactgcactt ttgccttttc ctcttgatat
     2761 tatgtttact gaaaaatgaa aactgtctgc catttttatc acttcctttc tttctttgtt
     2821 gttttaggtg gaggcttaat agttttttta tatcctcttt gtgaatgagc gttttgaaat
     2881 gatagaataa aaaaagccga ctactgaatt aatttttgtt gtttcagtat gtcggcttaa
     2941 ttgttacttt catttcaaat tttaaaagtc aagggcgagc cttagcgagt ttatttaccc
     3001 ttgactttta aaaagcgaat ggttgttgct ccctgcaagg gtttgactcc gcaggacgca
     3061 agcacccttt agggtgtata attgcgccct tgtaaccaag ggacaattat gttatttcat
     3121 ctttagatga tttttctaca ttatcatcta ttctttcttc taaaatttcc attatgttta
     3181 atcttatttc ttcatcattt aacgttttta ttaacttata aaattcatct tttgttaaat
     3241 caatactttc ttcaaaaata ctttcaaaca ctgcaccttt ttctataagt cttttgtttc
     3301 ttgcttttct ttcttgttca ttaagttttt tcttcaactg tcttttttga ttttgtaatt
     3361 gcttaatgct ttcttctttc ttttcaatct gttcttcaat acttaatctt ttacttgcca
     3421 tcatgtatcc tttcttaaaa taaaaaacga ctagattttt atttctaatc gttcttattt
     3481 taaatattat aatttgctat attgcatttt aattttaagt cttctatata tctttccatg
     3541 taattccagt ctggagtacc tctactgtct atcggtaatt taattttgat atctggcaat
     3601 actgtgctag atatttgatc tttatattca gtatttttta aagcttgcct aataattgaa
     3661 gttaaataga atgctacttc tttattcaat tctttatttt ttaattttaa acaatgaatt
     3721 ttcatatcta ggcttgcttt atatttatga taaaagactg ctcctaaaaa tgaaacagat
     3781 ataaaatttt caaaaactct ataattttta tcatctatat cttcgtagta acctaagata
     3841 ccattgtcaa tatttgtaac actaattcta ggagtttttc catcgagtaa atatcttttt
     3901 ggaatagatg agcctgttgg tacttgactc gatttcccct ttttttcggt aataaatatt
     3961 tctttttatt ttgttgtctg atatttttcc tacctgtcct ttgtaggatg agtattttct
     4021 agattttctt gaataacttt ttacttgaag ttttagcttt tgaactagtc gttgtacttt
     4081 ctttttgttt attatcagtc ctgatctttt taatattgct gttattctct atatcctatt
     4141 tttcattcat gatattcttt tactaatttt atcttaaatt ctgtgctgta tttgccatta
     4201 aaaaactgac ctcctttagt tagttttttg gcctaacttt tgagggtcag ttcaaaattt
     4261 gcgactttta aatgaattcc aatattcaat tattaagagc taacatggtg cttgccaata
     4321 ggaatcatta gaggcgaatt ggaaataggg tcacgtataa tttttgcttc aagattaaag
     4381 atatctttaa ctagtttatc atttagtata tcttcaggct ttccctctgc aacaagttta
     4441 ccttctttaa ttgcaaatag gtaatcagcg tatcttgctg ttagatttat atcgtgcaaa
     4501 atcatgcaaa tggttgtctt atatttttgg tttagatcag tcaagaggtc taatagttct
     4561 atttgatatg agatatccaa gtaagtagtt ggctcatcta aaagtaggat acttgtatct
     4621 tgggctaggg ctagagctat ccatactctt tgcctttgac ccccagaaag ttcttcaact
     4681 aggttatttg ctagatcttc aacattggcc ttaaccattg atctgtttat tatttcaagg
     4741 tcatcttttc caagactctt aaaaggcttt ctgtagggga aacgaccacg gcttacaaga
     4801 tcagctactg ttattgattc agggattatt ggagattgag gtaatatagc tatgtgtttt
     4861 gctaaatctt tttctttata agaattaatt gatttattat caagcaatac ttctccctct
     4921 aatggcttta taagtcgaga caaggtttta atgagtgttg atttcccaca accatttgac
     4981 ccaataataa ctgatatttt ttcttcaggt atttttatat ttatattttc caagattatt
     5041 ttttcatcat aaccgcaggt aagattattt gaccacagac ctttcattat atattcctcc
     5101 tgttcatttt tattagtaag tatattaagt atggtgaacc taacaagcca gttacaacac
     5161 ctactggata tctagctggt aaaatatttt gagagaatat gtctgataac aaaactagta
     5221 aaattccaac caatccagct aatattgggc ttcttttctt gccaatattt aaggctatgg
     5281 gaccagctaa aaaagatata caagctattg gtcctgtaat tgaagtagaa aaagcagtta
     5341 aagatacagc gcaaaaaatt aaaacaagcc ttgaaagctc gggatttgct ccaagtccga
     5401 ttgctatttc ttcaccaagt tcaataattt ctagtctttt attaaaaaat aaaactaata
     5461 tagtagcaat aatacttact attagaacaa gaggtatgtc atctaacttt gtaaaagata
     5521 aagagccact gagccatctc ataacttctt gtaattcata tcttgctact ttcaacaata
     5581 aaaatgaggt gcctgctctt gtgacagctt gaaaaccaat acctaatatt atcagtcttg
     5641 ctgctgaaaa accatctttt ttagctagta aaaataatat taaagatgat gttagtccac
     5701 aagttattga aataattcca gtagttaaac tatttgtttt taataccaat atgcaaaaga
     5761 ccgctgcaat agatgaagaa cttgtgacac cgattatatc aggacttgca agaggatttc
     5821 ttaacatagt ttgaaagata aatcctgcca atccaaaaga ccagccagct ataattcctg
     5881 ctaataattt tggtaatcta atttccataa tcgaaaaact agctccagga acagtttcac
     5941 tatttaagac tttaatcaaa gttgaaaaag aataactttc atctccgata agtaaaatga
     6001 aaaatgatag actgattatt attaataaaa atagtgagga aaatagtgtt attctatttt
     6061 ttcttttttg aatacctata attaaatttt gcattagtta ttaacccctc tatttttcat
     6121 agttacataa ataagtactg gacccccgat tattgcagta attatcccta cttcaatttc
     6181 acctggttta cctaacatac ggccgattat atcacatata agcaagagct ctgcacctat
     6241 aaaagatgaa gaaatggtca ttgtgcgtat atctttgctt ataaataagc cacaaaagtg
     6301 aggaactata agacctacga agccaatagg tccaccaatt gcagtaatac ttgaacataa
     6361 aagcacactt gcaattattg caagtgatct tatcctatta acattaactc caagaccaac
     6421 agccatttca tcacccatag ctaaagcgtt taaatctgat gaaataaata tagctatcaa
     6481 gtgacctaaa attataaaag gtagtagtgt agatatagaa gataatgtag ctgctccaag
     6541 gctacctatt tgccaaaatc taaatttgtc taagacgtta ttattcggta aaattaaaaa
     6601 acttacaaaa ctgcttaaag ccatactaac acaagttcct gataaggcaa gttttatagg
     6661 ggtaaggcct gcttttccgc ttacagcaat cgcgtataca aaaattgcac ttactaagcc
     6721 accaatgatt gcaaaactta tatggcttat gcttgatgaa attcctaaaa aagaaagacc
     6781 aattactaca ctaagacttg ctcctgtgtt tataccgagt atacctggat cagctattgg
     6841 gtttctagta actgattgca tcaatacacc gcttatggca agactagaac ctgctaaaat
     6901 tgcaaaaata gttctaggta ttcttttata tataattgat ttaataaaat catcatttgt
     6961 attacccatt ccaaaagctg ctaaaaaatc tctgatatta atttcttttg ttccaagctt
     7021 taatgacaaa aatattgtaa taagaagacc taggcagatt acaaaaatta tgcctaggtt
     7081 tatttgtttt ttatttcgca tttttgcatg catttcctaa aagatttagg tattcttcaa
     7141 tagtatagtt tattgaaagt ggtgttggag tgcatgaggc tgctaacggt gtattatctg
     7201 gaattacagc aacggcacca tttttaattg catttatttt acctaaaaga ggatcttttt
     7261 gtaaagcttc aagagtttta tcatcaccat aagttatgat tacatcagca tcatttatct
     7321 tatttgcttc ttctgcagaa atttcctttg caaaactatc ttcactctca aattctttta
     7381 atgattcagg gaaaactaga cctaaatctg ttaaataatt tgctcttgga tctttgctag
     7441 tataaatcca gaattttgat gtatctgcag cattaatcat agtaaataat actttttttc
     7501 ctttgatttt tcctttgatt tctggatgtt tttctaattc tttggatata cgagcttcag
     7561 tatttttgat taactcatca ccttcttttt ccatacctaa ggcttttgaa tcaattttaa
     7621 tcatatctct ccataaagtt tgccaaggtt tagatttgta tgctgctaca ggagcaattt
     7681 ttgatagagt gtcataatct tctttagtta taccagaata acctgctaag ataacatctg
     7741 gtttagaatt tgatattgct tcaaagttaa gtccatccaa atcgtcaaat aggttagctt
     7801 taccatttag ttctttgatt ttttcttctg tccatggtaa aactccttta tcagcactta
     7861 caccgtaatt tgcttttgaa aatccaacag gaactattcc taaagctaat gctacatcat
     7921 gatttcccca agcaatagtt gcaactcttt caggtttttt atctaatata gtttgaccga
     7981 aagcatgatc taaaactatt ttatcaggcg catgctcttt agaagtattt tcttcatttt
     8041 taacagaatt agaagaacaa gcgctaaaaa ctatacacat agctaaaata gctattagaa
     8101 aaaatttgtt tttcataaaa actccttaaa catatttcaa gtctattgta tcgataataa
     8161 ttatcattgt caatagatac agttacaaat ttaataatat aattttttca aaaaaggatc
     8221 tagtttttat ttttagttaa attatgtcta tatttttcat taactcatca ataaaaattt
     8281 gtttgctaat atctctttct tctgattttg tttcaaggat tattgctaca tcattcatat
     8341 ttttaggtaa ataccaacca tctggcttat ctgaatatcc cttgaagcct aattgattaa
     8401 aagtagttat ttgaccagta ccttgattga tgttttcttc aacttcatta aagcctatac
     8461 ttctcttgca taatccctaa cttgatcttc tgtccttaaa gtcattttct attcctcgtc
     8521 actaaaatta tcttcaaaac taataatatc attaggagtg caagataaag ccttacatat
     8581 tctttctaaa ttcttaaatg taattggttt atcctttccc atttgtgcca taacatttgt
     8641 tgtaagtcct gccatagcta ttacatctgt tttctttagt cctttttttg ctaactgtat
     8701 ccataatggt ttatagttaa gtgccataat atccctcttt ttttcttcat tagatttatt
     8761 taattatagc ataaatattg atttcattca atcttacatt gatttagtga tttgttttag
     8821 agaatttgtt gtgttattcc gtccttattt tgccataaat tgttttaagt gggacctctt
     8881 atccttacca tttttacctc ctaattttga gtataaaaaa gacgatagag tttttaattt
     8941 ctatcgtctg agatttacat attaaatttt catcacaaaa taagactctt taaagaatct
     9001 ttaaattcat tggtatgcta attacaatat ccattattaa aatggatact ataagcagca
     9061 caccaactat ttattttttg agttttaaac tttggtagaa gtcttgaact ccttatattt
     9121 acataactat ttgcctctat aactgttatg acacgaaacc aacaagcaag ttcaagcacc
     9181 tccatatctt tattcaaatg aggactaaga tattcacaaa ctttatcata aacctcttta
     9241 tcttttttca taaaaggggc atacaactta gcaaatttat cctaaaattt tttgttgcct
     9301 ttatcaatca tttcaacgct cctttaaata taaaaatgat cctatcaatc tttatattga
     9361 gcctattttc taattgatac cttgcaagaa aggaataata gctgttccta taccaagtag
     9421 gaatgtaata aatgcagaaa gtcatatact gtcattcttt tctattaaat cattttgaag
     9481 tgtctcaaag catccatgat ggcttcttct ttttcaggtg tacactgtgg aataatttgt
     9541 ttatcctttt tagacttgtt gtaatgttct cgtaattcta ttccacattt cttttttatc
     9601 tgtgcaatat ataatgtcga aacttttaat tcaaatttat tccaaacata ttctttgatt
     9661 tgagcatatg ttgctttgct ctccgcactt gtcaaatcca tctcatccag ctcaatttca
     9721 acacttatgt gcttatcgac atcgagtttg gacaaaagtg ctaccgtctc gacgtgatgc
     9781 gtttgaggaa atagatccac cggctggact ttcttcaatt catatcccaa ctcttggtat
     9841 agtttaatat cacgcgccat ggttgcgaca ttgcaggaga tataggcgat gcgatcggct
     9901 cctgtttggg cgcttgcttt gataaagctt tctgtcaagc ccttgcgtgg aggatcaacc
     9961 aagataacgg ttggttgaat cccatcttta agccaattct tcatagcatt ttcagctgtg
    10021 tcacagacat agtgggcgtt tgaaatattg ttcagctgag catttttttt actattctca
    10081 accgcttctg gaatcagttc aacaccgtag acttctttga catgcttggc gactgataaa
    10141 ccaatggttc caataccaga ataagcatca ataaccacgt catctttttt taactctgca
    10201 aagtcaatgg ctgtttgata gagtttctcc gccatttcag tattgacttg gtaaaaggct
    10261 gggccagcga tttggaagtc atttcccaac atctggtccg taatatagtc ttgaccataa
    10321 agagtgcgcc actccttacc aaaaatcgca ttggtattct ggtcgttgat attttgcatg
    10381 acagacacaa tctctgggaa ctgcttgata acttgttcaa tcaattggtc aacacgaaaa
    10441 acttttggac gagttgtcac caaaacgacc atgatttgcc ctgaatagtg accacgacgc
    10501 accacaagat tccgaatcaa tccagaatgt tccttttcgt cataaggttt taaatcaaaa
    10561 cgacggaaca ggtctcgaag agctactacg acttggtcaa tgacaggatc ctggataaag
    10621 aaatcttcaa ggagcatgag gttgtgcgaa ttcttacgga aaaatcctgt ttccaagaca
    10681 ccattcactc gacgaacggg cacctgcgcc ttattgcgat acttgactgg atgttccata
    10741 ccaagcgttt cagcaacttc tacatctgca attccagcaa tcttgtagag actgtccttg
    10801 acttgcttgg ttttaaactt gagctgttct ggataagaaa ggtgtcctaa atccgcgatt
    10861 cctgaacgca ggtaagccaa atctagatct tgattacggt gtggtgactg gacaaggtat
    10921 ttttcaactt ttccaaagcc aatcttttta ttgaccttga ggacacgcat gagaattttt
    10981 tcactcggta aagcattctc tacaaaaaag accaaaccat ctaccttggc aactcctgcc
    11041 ccttcatggg tcaaatcaac aatttcaact tctacaatat catttttctt taacattctt
    11101 ttctctttct attggccgac aaaaaagacg gcaacgttac ggttaccatc cattatacca
    11161 tgaaatttct taagaaccaa aactcttgaa gaagttgaca agggcttgcc agagggagct
    11221 taagaagtta ccaccgtcct ctagcgcctt atccgcatca aagttaaggt tgatattttt
    11281 aaaactgtcg ccagcttgtg atacgatgct ttgtttaagg tcatttaggg ttttagtgaa
    11341 atctgcattg ctgaggatat cactctttga gagattcaag gcaaaattga tgatgatatt
    11401 gatctggttt cctgttatga cctgatcaag tttgtaattt tttaaggtat cttcaacaat
    11461 cttgcgtaca tcttcttctg tcagatttcc cttgctttct ttagctttgg cgagtcctga
    11521 cttgatatca gctagggcaa cgtttaattt attagcatca tagcctgatt tgtccttgtt
    11581 ttcagcattg atatctgaca aagcctttag ctcttcttga gccaaatctt tattggcttg
    11641 cggcaccttg gctccattag cttctagcga atagtagatc ccagccaaag cactctcacc
    11701 tgtaactgga ataggggctg ctacagtgat tttggcatgt tccataccca gcgttactgc
    11761 tgcgtttcgg tacatatcct gagtcacctt agtgatattt tctggtgttt caatcttgac
    11821 ctcaagtggc gatttgtcac ctagcttttg aatcttggct gatgaataca actgtaagct
    11881 agagtcattg gccacattca tgattttaga ataaacatca ggtgtcatgg tcttgagttc
    11941 tttggtatct gttgaggcat tgtagcccag ttttttaaga gtttgatttt tttggtcttc
    12001 agatagggag gaacctagga catattcagg ttggacatag gtttcatcga taactttttg
    12061 aacatctgtt gctgcatggg cgctattcat agctgttact gcccacaaga ccgcagcacc
    12121 ggtcagaaag agtttctttc tcatagggaa tttcctcctt tacttttcta gagtaatata
    12181 tctatcttaa agaaaactta taacaaaaac acctggtcta gccagatgtt gaaaagagag
    12241 tgaaacattt gatgatgtaa aggttaagtc gtacctgtct agaataataa tagtttcctc
    12301 catttacata gagttcagca ccgtgaaaaa tggaaatggg gtgaatataa ctataagtct
    12361 ttccagtcct attaccaagc aagggggcaa cagtctcacg agagtactgt ttggctagag
    12421 ccaaggtatt ttccttgcca ttttgggcga taaaatcgat ataggcaggt ccaaaattat
    12481 aggcttgaac agctgtccag atatctacac ccttcttctg cgccagatag agattgcctg
    12541 tcagagtttg aatgccttgc cgaatgctag aggcattatc attgatggtg ttggtggaac
    12601 cacttgcaga ctcactagac tgcataacat cgccttcttt tccttttgtt tcagtataaa
    12661 tcatagcaag cacaagctct tcgtttgctg gggtgtcttt ttcactcaat atttctcgca
    12721 ccatgggttg ataggtcatg acttgtttga catcttgatg aacgcggtaa gctttatagc
    12781 cagcaaaaag gaagactgct agtacaagca ctcttcgaat tcgtttaaac attatttact
    12841 ttggatatcc tcgatatttt tgattaagat agagtaggtt ccattttcgt tttggataaa
    12901 ctcaacagac tcggcgtctt gatagacgtt attgggaacg atgagctcaa ttccatttga
    12961 taaggagagt ttttggtttt caaatttctt taattggcga ctggcatcaa tttcatcaaa
    13021 ttgaacaggt tctggtacgg cttctttgac ttggtcaata aagctcaaac gagccgtcag
    13081 attgttgtca aaaaggtcat tagccaattt ctcaggtgac aattcattgc tttcttctag
    13141 gttgttgaaa atagctgatt tgaccttgga ttgaaattga aaatcatctg tgttaaaaga
    13201 ttcagcaatt ctctgggctg ttttttccag ttccttgata gattttttag gagaaatctt
    13261 aggagcgaca gcaagaagat tatctgaaaa atagttcaaa aaagtcccgt tgtacttgat
    13321 tcgtttttca atcaggtgat acttgcgact ctgaagattg accaccaagg cctcgtcagc
    13381 acccgttcca aatccaggca ggttattctg agtcagcttg attggattat caacttctcc
    13441 tccgaggtgg gtcaaggtct cccgcagggc aattcgcaag aaagcgaaat gttctacacc
    13501 ttctttagaa aattgaacaa aaatcaagtc attggtcttg agattttcag aaatgctaaa
    13561 ctcctctttc cagagattag ccagcgttac tgatgtctcc aacaaatcgt ctgtaatatg
    13621 attgaagaag ggattttctt cttcgaaaat cccagtcttg gcttcatctg aatacacatg
    13681 ttcaattttt ttacgtaggt attcttcgat ttttggagta atattgagaa acttatctgc
    13741 taagaacagc tcggtatcat ccggactgaa ctggtgaata atggctttct taatataaat
    13801 atccataaaa gttttagtcc tcgtataatg ggaaggcatc tgtcaattct ttgactgcac
    13861 ttctcacttc ttctaataca gcctcatttt ctgaattctt aagggtttta atgatgagtt
    13921 cagccacttt gcgactttct tcttcaccaa atccacgtgc agtaatagct gctgctccga
    13981 tacgaatccc acttgtcttg aatggcgaca aggtttcgta agggattgaa tttttattta
    14041 gggtaatatt gacttcatcc agcaagtttt gagcaacttt tccgttttct acaaccttag
    14101 tcacatcaac aaggaagaga tggttttcag ttccacctga aataatacgg aaatcagggt
    14161 cttgcaagaa gacatctgcc atagccttgc tgttcttaat tacattggca gcatattcct
    14221 tgaaggctgg atccaaaact tctttgaagg aaactgcctt agccgccaca acatgctcta
    14281 aaggaccgcc ctgaatacct gggaaaatag ctgaattgat ttttttagca agttcttcgt
    14341 cattggtcaa aatcaaacca ccacgaggtc cacgaagggt tttgtgggtc gttgttgttg
    14401 tgatatgagc gtatggaact gggcttggat gaaggccagc cgcaaccaaa ccagcgatat
    14461 gggccatgtc caccatgagc ttcgcaccga cagcatctgc gatttcacgg aattttgaaa
    14521 aatcgataat ttgagaatat gctgaagcac cagctacaat cagttttggt tttacttctt
    14581 gggcttgttt caagatagca tcaaagtcta agagttccgt ttcaggatca acactataag
    14641 aaacaaagtt gtaggtttga ccagagaagc taacaggagc cccatgagtc aaatgaccac
    14701 ctgatgccaa atccattccc ataaccgtat cacctggctc aatcaaggac atgtaagccg
    14761 cacagttagc ttggcttcct gaatgtggtt ggacattggc aaatttagca ccgaaaattt
    14821 cttttgcgcg ttcaatagca agagtctcta caacgtctac tacatcagtt ccaccataat
    14881 aacggcgtcc tgggtaaccc tcggcatatt tatttgtcaa gatagaccct tgagctgcca
    14941 taacagcctt ggaaactacg ttttccgaag caattaactc gatattattt tgttggcgtt
    15001 cttcttcttt ggcaatagca ttccagagat cagcatcata tgctttaaaa tcatctttgt
    15061 caaaaatcat aggtcttctc ctttattgtg tgactagtcc attagtttga ttttacaata
    15121 agaaaatcaa actaaaagat gcgaataaac cgtttctgca ttttatcaca agtatagcca
    15181 actttttcat aaaatgcatg agcacccaga cgatgattgg cagaatttaa gcggataaac
    15241 ccataaccac atctttttgc ttcttcttcc aacccttgta gtaaactttt accaatacct
    15301 tgaccttgcg cttgaggtga aactgctaaa gctaagatat taaatcctgc tttggaatag
    15361 agtgattcgt aaacttcagc gtggacatat ccaagtaaga catgattagc tgcatcctca
    15421 tagccaagta ggaaatgatg ggaatcctga gacagtctag ctagttggct agccgtttcc
    15481 tctggactaa aagtataacc caaagcctct tggttgatgt cacatatcgc tttcacatct
    15541 gtttcttgca aatctcttag catttcaagc ctcctcaaaa gaaatctctg gcaaccgagc
    15601 aagaatatct tctcgtttaa ttgcgccttg gcgtaagatt ttcaccttgt ctccagacaa
    15661 atccacaata gttgaatcct gtccagttag aaaagcatcg tcttccagac ccagaacctc
    15721 ttggtcaaaa tccttcagaa tttgttcaaa ggttacacca cttgcctgac ctgagatatt
    15781 ggcagacggc ccaatcaagg gacctgtctc tcgaattaaa tccagtgtga tagggtgact
    15841 gggcatccga aatccaatag ttgcaaggtc agaatttacc caatagggaa ctcggtcatt
    15901 ggcttcgaga ataatggtca agggacctgg caaaaaggtc tctacaagtt tttgtagata
    15961 agttggctga ttcttagaaa agtgcaagat atcctcgaaa gaggcgatat tgagattgag
    16021 tgccttatct ctaggacgac gtttgagttg gtaaacatgg tcaactgctt tttcatctaa
    16081 ggccttggca aaaagaccat aaacagtctc tgtaggtaga acgacagctc caccattttc
    16141 caactcttgt ctaatcctgt ccatcatcaa ccacaaccat cctattttga ccaaattggt
    16201 ctttgagtgt tcgaactttt ttttcaggaa gatgttttct aaaaagttcg ggaacacttt
    16261 gaccttgctt gtatccaatt tcaaggtaaa tcttaccacc atccttgaga tagtcttttg
    16321 catcttccgc aattctacag taaatagcta ggccatcctc gtctgcaaag agagctagat
    16381 gaggctccga atgcaaaaca ttcaaaccta cctctgactc atcttcacga gagatatagg
    16441 gtggattgga tacaattata tcatattttt cagaaatttc tgcaaaacaa tcagattttt
    16501 taaaaaatat attaagattt tgatcgctag cattctctga tgcaagctct aaggcctctt
    16561 gagaaacatc tgctgctgtc actgaccaat ctggtctatt ttttgctaga gcgagagcaa
    16621 tagctccact acctgttcca atatccagaa ctgagagatt cgtctcaaga ttttcagtta
    16681 gaataagctc cactaactcc tctgtttctg gacgaggaat caaaacccgt tcatccacct
    16741 ttaaatgcat tccataaaaa tctgcctgtc caatgatgta ctgagctggc ttgtgagctg
    16801 ctagttgctg gtaaatatct tctacaaatt gtttttcttc ctctgttgtc acctcctgct
    16861 ggagggcaaa aataaagtct gtaaaagata gatttttcag actacgatag acaaaagaga
    16921 ggctttccgc ttcctctcct tgtcttatca actcttcttc aaaatttgaa aataattgag
    16981 ctaatttcat tatttgttta attcttctag tttttgtgtt tggtcataaa gcaccaaggc
    17041 atccacaact tcgtccaatt taccagacaa aatcgtatct agtttttgga gggtcaagcc
    17101 gatacggtgg tctgtgacac ggttttgtgg gaagttataa gttcggatcc gttctgaacg
    17161 gtcaccagta ccgattgtcg acttacgctc agcgtcttgt tcatcctgag caatctgagc
    17221 aaagtggtca gcgacgcgtg cacggataat cttcatagcc ttctcgcggt tcttctgctg
    17281 ggtacgttct tcctgcatct caaccttgat attggttggc aagtgaacga tacgaacggc
    17341 agtcgcaacc ttattgacgt tctgtccacc agcaccagag gcgtgataga tgtcgacacg
    17401 aaggtctttt ggatcaatgt cgtattcaac ctcttcaact tctggcataa caagaactgt
    17461 cgctgtcgaa gtatgaacac ggccttggct ttctgtcaca ggaacacgtt gcacacggtg
    17521 ggcacctgat tcatacttaa gcttagagta tacagactga cctgaaacca tagcaaccac
    17581 ttctttaaaa ccaccgacac cattcataga ggcttccatg acttcaaagc gccaaccttg
    17641 ggcttccgca tacttttggt acatagttag caaatctcca gcgaaaagtg ccgcttcgtc
    17701 tccaccagct gctccacgga tttcaaggat gatattcttg tcatcgtttg gatcctttgg
    17761 aaggagcaaa attttcagtt tttcttcata ttcttctttt tcagccttgg catctttgag
    17821 ttcttgcttg gccatttctt ccaagtccgc atctccgcct gattccttaa tcatctcttc
    17881 ggcatcgacg atattttgaa ggacttgttt atactcacgg taggctatta cggtgtcacg
    17941 attggaagct tcttcttttg aaagctccat aaaacgcttg gtgtctgaaa cgacatcagg
    18001 gtcactcagc aattctccta gttcttcata acggtcttct acagcttgta gttgatcata
    18061 gatgttcatt tttcttcatt ctccttattg atttcagggg caaaataatg tttacggcaa
    18121 accgagatat aggtttcatt accaccaatc tggatctgtt ctccatcgta aacgggcagt
    18181 ccatcctgtg ttcgcaacac catggtcgcc tttttcttgc aatactgaca gatggtcttg
    18241 atttcgtcaa tcttgtctgc taaaagcaag agatatttgg aaccttcgaa caattcattg
    18301 cgaaagtcat ttttcaagcc aaaagccatg acgggtatgt ctaactcgtc cacaacacga
    18361 gctaggtcat aaacatggtg gcgtttgaga aactgggctt catcgaccaa aacacagtaa
    18421 ggtttttctg gtaggtctcg gatatagcca aagatatccg ttgtttcctc aatcgcaagg
    18481 gcagggcgtt tcatgccaat tcgactcgac acatagccaa caccgtcacg cgtatccaga
    18541 gccgaggtca taatcacaac accttttcct tgctcctcgt agttataggc cactttgaga
    18601 atctcaatcg ttttaccaga gttcatggtc ccataacgat agtacaactg tgccatgttt
    18661 cttgcttcac gtccatttct aaatttttgc tacattctag tatatcataa ttttcttaag
    18721 ctttaaacgg caaaatgtgg taaaatggaa gaaatcaaaa ctagtggagg aagctattat
    18781 gccatttgta cgcatcgatt tatttgaagg acgcacgctc gagcaaaaga aagctcttgc
    18841 taaggaagta acggaagcgg ttgttcgcaa cactggagca cctcaatctg ctgttcatgt
    18901 catcatcaac gacatgccag aaggaactta tttcccacaa ggggaaatgc gcaccaaata
    18961 agctagctta agcagaattg cttaggcttt ttcaatctcc aagtagcacc cattgaagaa
    19021 atagtctaaa tttgttacaa tttgaaaaga gacttggaaa attccaagaa aagagcaatt
    19081 aattaaagga aacattatga ttacacgtga atttgatacc atcgctgcta tctctactcc
    19141 actaggtgaa ggggctattg gtattgtccg cctgagcgga acagacagtt ttgctattgt
    19201 gcaaaagatt tttaaaggaa aagacttgaa caaggttgcc agccacactc tcaactacgg
    19261 tcacattatt gatcctctga ctggtaaagt catggacgag gttatggttg gggctatgaa
    19321 gtctccaaag accttcactc gtgaggatat tatcgagatt aacacccacg gtgggattgc
    19381 ggtgaccaat gaaattctcc agctagctat tcgtgaaggg gctcggttgg cagaacctgg
    19441 tgaatttacc aaacgtgctt ttttaaacgg tcgcgtagac ttgacacagg cagaggctgt
    19501 gatggatatc atccgtgcca agactgacaa ggccatgaac attgcggtca aacaattaga
    19561 cggctccctt tctgacctca ttaacaatac ccgtcaagaa atcctcaata cacttgccca
    19621 agttgaggtc aatatcgact atcctgaata tgatgatgtt gaggaagcta ctactgccgt
    19681 tgtccgtgag aagactatgg agtttgagca attgctaacc aatcttctta gaacagcccg
    19741 tcgcggcaaa atccttcgtg aaggaatttc aacagctatc atcggacgtc ccaacgttgg
    19801 gaaatccagc cttctcaaca acctcttgcg tgaggacaag gctatcgtaa cagatatcgc
    19861 tgggacaaca cgagatgtca tcgaagagta cgtcaacatc aatggtgtac ctctcaaatt
    19921 gattgataca gccggtattc gtgaaacaga tgacatagtg gaacaaatcg gtgttgagcg
    19981 ttcgaaaaaa gccctcaagg aagccgactt ggttctacta gtgctaaatg ccagtgaaca
    20041 actgactgcg caagacagac aacttcttga aattagccaa gataccaatc gcattattct
    20101 acttaataaa accgacctgc cagaaacgat tgaaacttcg aaactacctg aagacgttat
    20161 ccgtatttca gtccttaaaa accaaaacat cgacaagatt gaagagcgaa tcaacaacct
    20221 cttctttgaa aatgctggct tggtcgagca agatgctact tacttgtcaa acgcccgtca
    20281 catttccctg attgaaaaag cagttgaaag cctacaagcc gttaatcaag gtcttgagct
    20341 ggggatgcca gttgatttgc ttcaagttga cttgactcgt acttgggaaa tcctcggaga
    20401 aatcactggg gatgctgctc cagatgaact catcacccaa ctctttagcc aattctgttt
    20461 aggaaaataa gaaaaatcca tgatccttca ttcggtcatg gattttattg tctttattag
    20521 taatctggtc ttaagacccc tgttacagtt gccttagttg cttcgtagtc gccatctacg
    20581 acaaccttga taatgcgttt ggcatcttct tctggtgctg gaacaagagg tagacgagtg
    20641 ggtccagctt caaatcccat atagttaaga attgccttaa ctggagcagg acttggataa
    20701 gagaagagag cattaacctt aggaatgaat ttacgctgaa ttgctgcggc tttcttcata
    20761 tcgctttctg caatggcagt aaacatctcg tgcatttcat ccccatttgt atgagaggca
    20821 acagaaataa ccccatccgc cccaaggttc atggcatgga aagcatctcc atcctcacct
    20881 gtataaatca agaactcttc aggcttgtgc tcaatcaagt aagccatatt agccaagcta
    20941 gtacattctt tgacaccgat aatatttgga tggtcagcca agcgaagcat ggtttctgga
    21001 gtcaattcga caactacacg ccctggaatg ttatagataa taattggtag gtcagaagca
    21061 tctgcaatag ccttaaagtg ctgatacatc ccttcttgag aaggtttgtt gtagtaagga
    21121 acaatagcaa gcccagctgc gaaaccacca aattccgcta cttctttgac aaactcaata
    21181 gagtcacgcg tatcattagt acctacaccc gcaatcaaag gaacgcgtcc attgacaacc
    21241 ttttgtacag ccgcaaacaa ctccaactcc tcatcgtggg tcaaagttgg actctcagca
    21301 gtcgttcctg cgagaagaat tccatccgta tgatgggcca ataaatgctc aatcaaggct
    21361 ggaatagcat caaagttaat ggaaccatcc tcatggaagg gggtaataaa ggctgtaatg
    21421 attttacatt cttttaaatc ttgataagac acgaaaacac ctctctattt caaagaagga
    21481 gttcatctga actcctaaac gatatgacta ttttaattca aatttcaatt cagctgttgg
    21541 acgaaccaat ccacgttcat gaagagtttc agcaatctga actgagttcc aagcagcacc
    21601 tttgagaagg ttatctgaaa caacccacat gtgaattcct ttttctgcat ccaagtcttt
    21661 acggatacga ccaacaaagg tatcacgtga accaactgca ttgatggctt gaggatagat
    21721 ttgatgaact acatcatctt caagaacagc acctgggaag gatgcgatag ctgctttgac
    21781 ttcttcaatt ggagccactt cctttgtttc aacataaact gactcagagt gagctgacaa
    21841 gactggaata cgcacacatg tcgcagatac tgcaatgcta tcatcttcca taattttctt
    21901 agtttccttg gtcatcttca tctcttcgta cgtgtaatca ttatcagtga agacatcaat
    21961 ttgtggaaga gcgttaaagg cgataggata atgtttcttg tcaccacctg aaggcaagat
    22021 ttccgcatgc aaatcacgtg gtttcactcc atcattcaag acctcacgaa gttcacgttg
    22081 tgtctcaaga attgctccca taccagcacc tgaaacggct tgataagttg aaacaatgat
    22141 acggtccaag ccccattttt ggcgaaccgg ctcaagagcc accatcattt ggattgttga
    22201 acagttaggg caggcaatga ttccgttgtg ggcatcaagt gcatgagcat tgacctctgg
    22261 aacaaccaaa ggaacatctg gattttgacg gaaataagat gtattatcca ctactaccac
    22321 gccagctttt actgcgtatg gtgcatactt agctgatgtc gaaccacctg ctgaaaagag
    22381 agcaatatca actccttcaa aagctgtttc agtcgtttct tcaatcgtaa tatcttgatc
    22441 tttaaatttc aatgacttac ctgctgaacg tgcagaagca aggtaacgga ttttatcgat
    22501 tggaagtgtt gattcttcca acatttttat catctgagca ccgacagcac ctgtcgcgcc
    22561 gactacagca actgtatatc ccataaataa cctctttcgg aattttctaa aaatttctat
    22621 aatagaagta ttatactact ttttccatga attgcaaagc tttttcatca ttttttggaa
    22681 aataaaaatc cccaatcgct agactaggga ttaagaggca tcttcatgtg atgagcaggt
    22741 tcacacaact catcaaggtc cgctcctgcg ttatgacctc cttatgctca atagtagccc
    22801 gaagactacc tatcgactca tcgcatctac tattctacta aagagaatga cttttgtcaa
    22861 cagacgaaac tctttatact cttcgaaaat ctcttcaaac ttcgtcagcg tcgccttgcc
    22921 gtatgtatgg ttactgactt cgtcagtttc atctacaacc tcaaaaacat gttttaagct
    22981 gacttcgtca gttctatcta caacctcaaa gcagtgcttt gagcaacctg cggctagttt
    23041 cctagtttac tctttgattt tcattgagta ttagttttat ttacacaggt gcataagaaa
    23101 tatattggaa aaattggggg cagacataac aaaaaccctt gtaaatcaag ggcttttctg
    23161 tctatttaat gctaattgcc gggattgaac cggcgacctc atccttacca tggatgcgct
    23221 ctgccaactg agctaaatca gcttacttaa gaagtatact atattcagaa aaacttgtca
    23281 agtttcctta gaaattttcc ataggaaaaa gccaggtaag aactacctag cttatcttct
    23341 tctatttact taaatcaatt cgacgaccaa ttttaccaat aataatcgct ccaataatca
    23401 atgaagcaaa ttcaccgatt cctgttgtaa accaagtaag gaagaatggt aattctgcta
    23461 caatatttaa ctctgcagcg atagtaaaca tggaaattga aaagaggatt gaaaagaaga
    23521 aatgatcttt tcgaatcaat ccgttaaaga ggtaatcctt gctatatttt gcaaaaagcc
    23581 aaacacctaa actgaggaat actaaggttg aaccaccacc aacaaagaca tctagcagtc
    23641 cgaagctaaa gaaattagca atcatacaac cgatggtaac tccgatgatg tacttaggat
    23701 tgtaaaaagc cataaagttc atcatttctg aaatacgaaa ctgataagca ccatagctga
    23761 tggcatttag gggcggtgtg acagtcaaaa cgacgtagat agcagcgacg attgcaatat
    23821 ctgcaacatc acgaatagtt aattttttca tcttttctcc tttggcggtt atccgcgtgt
    23881 aatatgcttg gtgaaagaag ctaagcacca agggttgatt cattcaacct tactagtata
    23941 gcacaatagc ctgctttatg ctatacttaa agcatgaaaa aacctattca aaaatttttt
    24001 aacaatgaaa tcttagccta tctctttttt ggccttgcga caactctagt ttcgattctc
    24061 tcacgactag tcatttatca actaagtcat caggaactcc ttgctacggc cttggcaaat
    24121 attatcggta tcttatttgc ctttatcaca aatgatacga ttgtatttaa gcaaaaaaag
    24181 aaaaatagac ttatccgttt agtgaaattt tctcttgctc gcctttctac ttttctgtta
    24241 gacttgtttt taacttttct ctttgtaacc caatttcctc acatcatagg gcaattcgta
    24301 actgaaaaca ttgataagat aaatgctatt gaaacaataa ttgcacaaat attcattatt
    24361 atcatcaatt atatcttgag caaggtctat atttttagaa aataatgctc catttatgag
    24421 ccttttaatt gccttctata atgatttagg atacaatgaa acacgaaaca ttgaaaggaa
    24481 aacagtatgt taaaaaatct aaaatcgttc ttgcttcgag gaaatgttat tgaccttgct
    24541 gtcggtgttg tcattgcctc tgcttttggt gctatcgtta cttcacttgt aaacgacatt
    24601 atcactcctc ttattttaaa tcccgctttg aaagctgcta aagtcgaacg tatcgctcaa
    24661 ctttcttggc atggagtcgg ctatggtaac tttttaagtg ctattatcaa ttttatcttt
    24721 gtgggtaccg ccctcttctt tattatcaag ggcattgaaa aagcacagaa actgactggc
    24781 ataaagaaag aaaaaactgc cgaaaaaaaa ccaaccgaat tggaagtcct tcaagaaata
    24841 aaagctctcc ttgagaaaaa ataatcgatt aaaaggatct agcgcaaagc taaatccttt
    24901 tttctttact ctttgggtaa cttgcctgct ttttcaagca tttttttgat aagataaggc
    24961 atcttaacat tctcccgccc ttttttctca atcagttttt tcacaaattc tggcatttgt
    25021 aaatcttcag attcagctaa aatgtttttc gtctcgtctg aaggaactaa ctcatcaaag
    25081 gtctcttctt ctgggagaaa ttccttaaac tcttgatttt cattgactct aactgtattg
    25141 accaaagcat caatcaaacg agaatctgta tttggcattg gtggacgatg gtagtttacc
    25201 ccaaattcct ggcataagtc ataacattct acatcattgt caaacaagac ctcaatatgc
    25261 tcactgatga aactaatagg tacaaaaata taatggtctg gatgttctgt ctgttctctg
    25321 agatactcca aaacatctgg tttaatccat ggaataccaa tatcactctc actctgccaa
    25381 gtgttggtat attgttctga actcaagccc agtttttcag cgactagctt gctattttcg
    25441 aaaatttggt ctatataagg atcaccaaag tccaaggcaa aaatgggcac actatgggct
    25501 gaaaagatga ctttaaagct gtcttgcttt acttcttctt ttaaaatctt agcaatttca
    25561 tctgcccaat agtttaagag cgcttcttcc tgataccagt ccttaatgac caaaaattga
    25621 atttgtttgc tttctaaaaa tttttcatag cccatgacag agtagaaaga ataatggggc
    25681 tccaaaatca agcaaataca ctgttcaatt ccgtctgctt ccatttgacc gatcacatct
    25741 ggaataaagg gactggaaaa cttattagca aagtagacac tgtattcatt ccccagccta
    25801 gcttctacca aggcaacctc ttgacgggta attttttgca gaggcgtgcc tccaattcgt
    25861 acataattat catagagagt ctgaatctcg tggtcttggg gtctcacccc acgacgaata
    25921 tttgtgaaaa aatcagctac accttcaaag gtaatctctt ctggtgaacc gaaggtcatc
    25981 attaaaattg cttttttcat gactgcttcc ttgtgatgtt tttatcaagt ttattttatc
    26041 attaattaat cgataagtaa acgctaatat agggacattc tcaatcttct gtcttttgtt
    26101 tttctcttct ttctatgata caatggaaaa aataaattca aaaggagttt ttttatgact
    26161 tatccaaatc tcttggaccg cttcttaacc tacgttaagg tcaacacgcg ctctgatgaa
    26221 cactctacta ctactccaag tacacagagt caggttgact tcgcaacaaa tgtcctaatt
    26281 cctgaaatga aacgtgttgg actgcaaaat gtttactatc taccgaatgg ttttgctatt
    26341 ggaaccttgc cagccaacga tccgtcttta acacgtaaga ttggttttat atcgcacatg
    26401 gatactgctg attttaatgc tgaaggagtc aatccacagg taattgaaaa ctacgatggt
    26461 ggtgtgattg aactagggaa ttctggtttc aaactcgatc cagctgactt caagagtctt
    26521 gaaaaatatc caggacaaac gctcatcaca acagatggaa caagcttgct aggtgctgat
    26581 gacaagtcag gaattgctga aattatgaca gccattgaat atctaactgc tcatcctgaa
    26641 attaagcact gtgagattcg tgttggtttt ggtccagatg aagaaatcgg tgttggtgcc
    26701 aataaatttg atgcagaaga ttttgatgtg gattttgcct acactgttga tggtggtcca
    26761 ctaggtgaac ttcagtacga gactttctca gccgctggtg ctgaattgca tttccaaggc
    26821 cgtaatgtcc accctggtac tgccaaagag cagatggtca atgcccttca gctagcaatt
    26881 gattttcata atcaacttcc agaaaatgac cgacctgagt taactgaagg ttaccaaggt
    26941 ttttaccatc taatggatgt gacaggtagt gttgaggagg tgcgtgcaag ctacatcatt
    27001 cgtgattttg aaaaagatgc ctttgaagcg cgtaaagcat ccatgcaatc tatcgctgat
    27061 aagatgaatg cagaacttgg gagctaccgt gtcactctca acttgacaga ccagtactac
    27121 aatatgaaag aagtcattga aaaagatatg actccaatta ccattgctaa agccgttatg
    27181 gaagatctag gtatcacgcc tattatcgaa ccaatccggg gtggaacaga cggctctaag
    27241 atttccttta tgggaatccc aactccgaat atctttgcag gtggcgaaaa tatgcacgga
    27301 cgttttgaat acgttagcct tcagactatg gaacgtgcag ttgataccat cattggcatc
    27361 gtagcttata aaggctaaaa agacgaggta gctcagctac ttcgcctttc tttttattct
    27421 actggttttt cttgatttcc agtagttgta gaagattctg ttgtttcatt ttctgaagtt
    27481 gattcagcag gtttagaatc tcttgtattg cttggtttgt tttcgtcgct agcaatttca
    27541 atgttagatt ctgcagttgc gtttggttgg ttctcagcac tggtgttatc actatttgct
    27601 tcagcatttc ttgctggact tgtttcttca cttgcgctag cttttgactg gatttgatga
    27661 ttcaaaacta gaatagcttt tgtcgattca agtaaagctg ttttgtcttt actcttagca
    27721 gaaagttgat ctaataatgc atccacctta tcaaagtccg catcagatcc attattactt
    27781 tctaaataag agtgaagcga catgagaata tcgtagagtt tttgatagag tacaagtgtc
    27841 tgagaatctt gctcagcatt ttccttttct tgttgaaggg cgctagcgat acgagtcaag
    27901 acatctttta cctgactgtt tacttcatcc aagtctgcat cagccttgtt tgtggcagct
    27961 tttagatttt ctacttcttc tgccaaggat tgtctgattc cttcttcatg gatttgttcc
    28021 aagagttgat ttaccttgct caaaagactt tctacttctt ccttgctatc tgtcgcagat
    28081 tattggttgc catctaccat gtactcctaa aacaggagag ttataatcca agattacaag
    28141 gccttacaga aataagaaat ccagataaga caatgttcgt ccaagacgct attcgcttcg
    28201 cacagcagca cggattcaat atgctttaat tttaaagttt aggtgtcaag acctcttttt
    28261 agtgtgccca aaatttagag aagtaatcaa tcaactaact tttatttttt tcaaactttc
    28321 agtaaactga cctaaagcta actcaatctg tctttgtaga tgcttctgct atcagctaga
    28381 agttgatcta cttttgccaa gactgccttc tcatcaaaag ttccaggttg atagttggat
    28441 tgcagggatg gaatcttgtt tttcaaagcc gcttcatatc ccttagtttg aaccttgatg
    28501 tagtgattgt ggtcgccatg aggaatcaca aaaccttctg aatcttcact tataattcga
    28561 ttggcatcaa aaccatgacc atcttcttcc tcatgatgga catgtagtga cggattactt
    28621 aatacagaac tagaagaact tcctacctct tccgtgttag agtgtgatgg gggattgtta
    28681 agagatgact taggaatata gtgatagtga tccccatgtc ttactatata agcatcacct
    28741 gtatctctga caatatcatt agggttaaag acatatgtgg ctgctaattc acctgccgac
    28801 aagtcactct caggaatgaa atgatagtga ccaccatgtg gtactatcgt agattgaaat
    28861 agaatatgag caaattgata aggggatttt aaagtaattt ctaacaatga tttagaaact
    28921 atgatgtgct attctaaatt caactcacta tatataacca tcatcggtag tataacgtcc
    28981 ctgtaatttt gctacagata cttctgcact agctccttta tcgtctttac catgttcttg
    29041 tttttggcga ttgatttcat cttttattcg tacattttct gcatgagctt gatctttaag
    29101 gtaaacataa tactttccat ctaccttaat aatatatcct cccttaacct aactgacgat
    29161 atcttgatct ttcggctgat agttgggggc tttcattagt agctcttcac taaagagcgc
    29221 atccaaagga actttaccat tatagcagtg ataatgatcg ccatgagaag ttacataacc
    29281 ttgatctgta atcttaataa caatttgttt tgcttgaatt ccttcttttt gactaaccta
    29341 gtctggagtc aaattttcag tcttcttagt gtctttatta ctgtttacat atgaaacacg
    29401 atttttatct gtattggcct gttagctatg ttggttcaga gcataaacac acagacttaa
    29461 ggaaaggata acaacagatc cagctgctat atatttcttt ttaaatttca taattacctc
    29521 atttctataa ttatttatat gatgtcttca ttattaaatg attaaataaa ttaattaacc
    29581 aattaattaa ctagtaaata ttccacctct ttttaagttg tatgtcaaga aattttatat
    29641 attaataata aaatgaaatt ctcccaaagt cagagtttta tttctaactt ttgagagaac
    29701 ttcatttttg attcagactt tttctactgc tattccttac gctatgagat cagataaatt
    29761 cttttttatc acttctccac ttggcaatct taattcaatc gttccatcca tattgaatat
    29821 aacactatct aaacctaatc cgtaactagc tgtaaatttt tctaattttt cttgtacagg
    29881 atctactgct ggagcttcct ctaatgctgg atctaacata gggtcactcc ccacattccc
    29941 ttctggattc aacattccat tatccgttga gttttctggt tttacaggtt ttttgtttgg
    30001 tgcctctggt aaagaatctg ctggtttatt ttctgttggt tggttctcaa ctgttccagt
    30061 agatactttt ccattttcag atggtttatt ttcaccattt ccttgaggtg cttctcctgt
    30121 aaaatctgcc atattctttt taatgacttc tcccgatggt aaatataatt caattgttcc
    30181 gtccatatta aacaagacat tttctagctt catcccataa ctttcagcaa attttgctac
    30241 tttttcttgt acaggatcca ctgtaggaac ttcttctaac gttgaattac tagtactatt
    30301 cccagtttca gaaagttttt ctttttctac cttctcacta gtctttggtt cttctacctt
    30361 ttcatcaagt tttgagtttt cttgtgcttt attcctttta aattgtggta gaatacttgg
    30421 tttatcagtt tgattttctt tttccaagat aggtacttcc acaatataag tcgattgatt
    30481 gtccaaataa gcatttgcca tgaaggttac aggaatttta tttccggccg ttctggttgt
    30541 tccttggttt aatttcggaa tcggtaattt aatttcacca actttatagt tattttctaa
    30601 ataagcattt ccatgaaatt catcaaacac tctgactaaa gcatcagttc ctttaggcac
    30661 tgcaaattga gggttcactc ttaaataagt atcccctgca tggaaaggat agaaaatcgt
    30721 ttgactggcc attttgtaag ctaaagaggt tggaactgta aatgtaccat cataacttac
    30781 ttctggataa tcttttgaag cgatagtata cttaaatgtt tgtcctggta aataaggttg
    30841 atctaattca aagtttgcaa tattccctac tccttctcca aatactttac cagatacttt
    30901 ctccaatact tttccatctg gtgttattaa ttttactagc atattgatac ctaatttttt
    30961 ctccaattca ggcggaaaac taaaagaaac gcgtttttga ccattggcta gagtaaagtt
    31021 ttgattatta aacgtactat tttttaacaa attaacaaca ttcgttaatt cttctccagt
    31081 ataaacttta ttcccttctt ttttagcaac tccttcttcg ggtttaaaca gttcatagtt
    31141 actgtgagaa tgaccaattc caaccggttt atgttcatca atcggatctg catgatggtg
    31201 atctccatgc ggataaataa tcgcattttt ttctttattc acgacaatac tttcacgttt
    31261 gacaccatat tgtttcataa tgccagcaat tttttcttca atttttttat ctaaatcttt
    31321 catttctttg gcattacttg gataatcctg ttcatgagat gacaaagaat ctaatccatt
    31381 atgactagtt ttaacttcct ctaaatgttt ttgcgcagcc ttaatttgct cttctgtcaa
    31441 gtccttcttg aagaaataat gattgtggtc tccgtgactc atgacaaaac ctgattcatc
    31501 ttcagagata atacgattag catcaaatcc gtatccatct tcttcatgtt tctcatgtga
    31561 agttcctgga ttgattggaa gagatggaga aggtgttgct agactattgt ttggaagagt
    31621 cggttgccca atttgatttg attttggaat gtaatggaaa tgatcaccat gtcttacaat
    31681 ataagctgta gccgtttctt caacgatatc ttttggatta aaaatataac catcagatgc
    31741 tgaagagagc tccttacttg tcgttaaaga agaaggattg cttgaaagac tgcctagact
    31801 agacactact tcattaggtt ttgcatttgt agaaactgta gaaccagttc cactgatagg
    31861 caccattctg gcaatctttt cttctaaggc agaaagcttg ctgtaaggaa taaagtggta
    31921 atggtcgcca tgcggaatcg caactccatt tggtgtacga ctgataatct tagcagggtc
    31981 aaagaccagg ccatctgatt cactgtaacg ttgggcgcta ggtgaatcat agagttcctt
    32041 caaaagactc tggagatttt cagatttatt tgctggcttg ctagttgatc cttttgctac
    32101 agattgcgtg ttattgtcac tagctgttga agaatagctt aactgactcg gttgcatatt
    32161 ttttccaacc agatgtgctt tagctgctgc taattcacta gcagataaat cgcttttggg
    32221 aatgtagtga tagtgacctc catgaggaac gatataagca ttacccgtat cttcgataat
    32281 atcagctgga ttaaagacat aaccatcatt tgtcgtatat cgtccctgag accttgctac
    32341 agcaacatta gagttaacct tctcattatc tttgacatgt tcttgttttt gacgattgat
    32401 ttcatcttta gttcgaacat tatcagcatg agctgcatct ttcaggtaga cataatattt
    32461 tccatcgacc ttgatgatat aaccaccctt gacttcattg acaatatcag cgtctttaag
    32521 ttgatagttt ggatccttca tcaagagttc ttcactaaag agggcatcat aaggaacttt
    32581 cccattatag taatgatagt ggtcaccgtg tgacgttaca tagccctgat ctgtaatttt
    32641 gattacaatt tgctcagcct gaattccttc tttctggcta acctggtctg gtgtcaagtt
    32701 ttcacttttc tgacttgact ggctgccatc cacataagag acacgattat tgtccttatt
    32761 ttcctgcgaa cgatgctggt ttagtgcata ggcacataga ctcaaggata cgataacagc
    32821 tgatccagct gctatatatt ttttactaaa tttcataaat ccctcatttc aataaatgat
    32881 gaagtttttt ctcaacttct tttactttat taaatagttt tctaaaccgg ttatttaacc
    32941 atttaattaa ccagtaaata gtttactatt taaaattact tttgtcaagt ttctgttacg
    33001 tttttctaaa aaagagaagt aacacgaaag gttacttctc cataaaatat gctccattca
    33061 ttttactact gtatcggagc cggttgactt ttttttaaca aagccaagag actatctact
    33121 tctgctgaaa tagtgttatt atctttcgtt ccgagaagaa gactactttt tagaccagtc
    33181 aatgtctcca tagcattttg tctaatacta gaatctgtta ctttttctag caaggcctcc
    33241 gcctctgcta tcttagcgtt aataacagaa ttctctactt gaggaatttc ag
//
LOCUS       DBEJHE010000023        29484 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC4 isolate 671759
            SAMN38261586-rid24793303.denovo.23, whole genome shotgun sequence.
ACCESSION   DBEJHE010000023 DBEJHE010000000
VERSION     DBEJHE010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261586
            Sequence Read Archive: SRR26833752
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 29484)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29484)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576136.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576136.1
            Genome Coverage       :: 109x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 19:48:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,067
            CDSs (total)                      :: 2,029
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 131
            CDSs (without protein)            :: 131
            Pseudo Genes (ambiguous residues) :: 0 of 131
            Pseudo Genes (frameshifted)       :: 64 of 131
            Pseudo Genes (incomplete)         :: 59 of 131
            Pseudo Genes (internal stop)      :: 46 of 131
            Pseudo Genes (multiple problems)  :: 32 of 131
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29484
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261586-rid24793303.denovo.23"
                     /strain="GPSC4"
                     /isolate="671759"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            <1..1337
                     /gene="nanB"
                     /locus_tag="ACL3EZ_001428"
     CDS             <1..1337
                     /gene="nanB"
                     /locus_tag="ACL3EZ_001428"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="neuraminidase NanB"
                     /protein_id="HGR0392979.1"
                     /translation="SGRVLSSIDARYGGTHDSKSKINIATSYSDDNGKTWSEPIFAMK
                     FNDYEEQLVYWPRDNKLKNSQISGSASFIDSSIVEDKKSGKTILLADVMPAGIGNNNA
                     NKADSGFKEINGHYYLKLKKNGDNDFRYTVRENGVVYDETTNKPTNYTINDKYEVLEG
                     GKSLTVEQYSVDFDSGSLREKHNGKQVPMNVFYKDSLFKVTPTNYIAMTTSQNRGESW
                     EQFKLLPPFLGEKHNGTYLCPGQGLALKSSNRLIFATYTSGELTYLISDDSGQTWKKS
                     SASIPFKNATAEAQMVELRDGVIRTFFRTTTGKIAYMTSRDSGETWSKVSYIDGIQQT
                     SYGTQVSAIKYSQLIDGKEAVILSTPNSRSGRKGGQLVVGLVNKEDDSIDWKYHYDID
                     LPSYGYAYSAITELPNHHIGVLFEKYDSWSRNELHLSNVVQYIDLEINDLTK"
     gene            1350..2453
                     /locus_tag="ACL3EZ_001429"
     CDS             1350..2453
                     /locus_tag="ACL3EZ_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HGR0392980.1"
                     /translation="MVKYGVVGAGYFGAELARYMQKNDGAEITLLYDPDNAEAIAEEL
                     GAKVASSLDELVSSDEVDCVIVATPNNLHKEPVIKAAQHGKNVFCEKPIALSYQDCRE
                     MVDACKENNVTFMAGHIMNFFNGVHHAKELINQGVIGDVLYCHTARNGWEEQQPSVSW
                     KKIREKSGGHLYHHIHELDCVQFLMGGMPETVTMTGGNVAHEGEHFGDEDDMIFVNME
                     FSNKRFALLEWGSAYRWGEHYVLIQGSKGAIRLDLFNCKGTLKLDGQESYFLIHESQE
                     EDDDRTRIYHSTEMDGAIAYGKPGKRTPLWLSSVIDKEMRYLHEIMEGAPVSEEFAKL
                     LTGEAALEAIATADACTQSMFEDRKVKLSEIVK"
     gene            2627..3325
                     /locus_tag="ACL3EZ_001430"
     CDS             2627..3325
                     /locus_tag="ACL3EZ_001430"
                     /EC_number="5.1.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009385 - N-acylmannosamine-6-phosphate
                     2-epimerase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006051 - N-acetylmannosamine metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019262 - N-acetylneuraminate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HGR0392981.1"
                     /translation="MPQISKEALIEQIKDGIIVSCQALPHEPLYTEAGGVIPLLVKAA
                     EQGGAVGIRANSVRDIKEIKEVTKLPIIGIIKRDYPPQEPFITATMKEVDELAELDIE
                     VIALDCTKRERYDGLEIQEFIRQVKEKYPNQLLMADTSIFEEGLAAVEAGIDFVGTTL
                     SGYTSYSPKVDGPDFELIKKLCDAGVDVIAEGKIHTPEQAKQILEYGVRGIVVGGAIT
                     RPKEITERFVASLK"
     gene            3344..4861
                     /locus_tag="ACL3EZ_001431"
     CDS             3344..4861
                     /locus_tag="ACL3EZ_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000477452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HGR0392982.1"
                     /translation="MFKVLQKVGKAFMLPIAILPAAGLLLGIGGALSNPTTIATYPIL
                     DNSIFQSIFQVMSSAGEVVFSNLSLLLCVGLCIGLAKRDKGTAALAGVTGYLVMTATI
                     KALVKLFMAEGSAIDTGVIGALVVGIVAVYLHNRYNNIQLPSALGFFGGSRFVPIVTS
                     FSSILIGFVFFVIWPPFQQLLVSTGGYISQAGPIGTFLYGFLMRLSGAVGLHHIIYPM
                     FWYTELGGVETVAGQTVVGAQKIFFAQLADPAHSGLFTEGTRFFAGRFSTMMFGLPAA
                     CLAMYHSVPKNRRKKYAGLFFGVALTSFITGITEPIEFMFLFVSPVLYVVHAFLDGVS
                     FFIADVLNISIGNTFSGGVIDFTLFGILQGNAKTNWVLQIPIGLIWSVLYYIIFRWFI
                     TQFNVLTPGRGEEVDSKEISESADSTSNTADYLKQDSLQIIRALGGSNNIEDVDACVT
                     RLRVAVKEVNQVDKALLKQIGAVDVLEVKGGIQAIYGAKAILYKNSINEILGVDD"
     gene            4986..6314
                     /locus_tag="ACL3EZ_001432"
     CDS             4986..6314
                     /locus_tag="ACL3EZ_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGR0392983.1"
                     /translation="MKFRKLACTVLAGAAVLGLAACGNSGGSKDAAKSGGDGAKTEIT
                     WWAFPVFTQEKTGDGVGTYEKSIIEAFEKANPDIKVKLETIDFKSGPEKITTAIEAGT
                     APDVLFDAPGRIIQYGKNGKLAELNDLFTDEFVKDVNNENIVQASKAGDKAYMYPISS
                     APFYMAMNKKMLEDAGVANLVKEGWTTDDFEKVLKALKDKGYTPGSLFSSGQGGDQGT
                     RAFISNLYSGSVTDEKVSKYTTDDPKFVKGLEKATSWIKDNLINNGSQFDGGADIQNF
                     ANGQTSYTILWAPAQNGIQAKLLEASKVEVVEVPFPSDEGKPALEYLVNGFAVFNNKD
                     DKKVAASKKFIQFIADDKEWGPKDVVRTGAFPVRTSFGKLYEDKRMETISGWTQYYSP
                     YYNTIDGFAEMRTLWFPMLQSVSNGDEKPADALKAFTEKANETIKKAMKQ"
     gene            6566..7432
                     /locus_tag="ACL3EZ_001433"
     CDS             6566..7432
                     /locus_tag="ACL3EZ_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGR0392984.1"
                     /translation="MRETVISYAFLAPVLFFFVIFVLAPMVMGFITSFFNYSMTKFEF
                     VGLDNYIRMFKDPVFTKSLINTVILVIGSVPVVVLFSLFVASQTYHQNVIARSFYRFV
                     FFLPVVTGSVAVTVVWKWIYDPLSGILNFVLKSSHIISQNISWLGDKNWALMAIMIIL
                     LTTSVGQPIILYIAAMGNIDNSLVEAARVDGATEFQVFWKIKWPSLLPTTLYIAIITT
                     INSFQCFALIQLLTSGGPNYSTSTLMYYLYEKAFQLTEYGYANTIGVFLAVMIAIVSF
                     VQFKVLGNDVEY"
     gene            7448..8287
                     /locus_tag="ACL3EZ_001434"
     CDS             7448..8287
                     /locus_tag="ACL3EZ_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGR0392985.1"
                     /translation="MQSTEKKPLTAFTVISTIILLLLTVLFIFPFYWILTGAFKSQPD
                     TIVIPPQWFPKMPTMENFQQLMVQNPALQWMWNSVFISLVTMFLVCATSSLAGYVLAK
                     KRFYGQRILFAIFIAAMALPKQVVLVPLVRIVNFMGIHDTLWAVILPLIGWPFGVFLM
                     KQFSENIPTELLESAKIDGCGEIRTFWSVAFPIVKPGFAALAIFTFINTWNDYFMQLV
                     MLTSRNNLTISLGVATMQAEMATNYGLIMAGAALAAVPIVTVFLVFQKSFTQGITMGA
                     VKG"
     gene            8559..9011
                     /locus_tag="ACL3EZ_001435"
     CDS             8559..9011
                     /locus_tag="ACL3EZ_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HGR0392986.1"
                     /translation="MIFDDLKNITFYKGIHPNLDKAIDYLYQHRKDSFELGKYDIDGD
                     KVFLVVQENVLNQAENDQFEYHKNYADLHLLVEGHEYSSYGSRIKDEAVAFDEASDIG
                     FVHCHEHYPLLLGYHNFAIFFPGEPHQPNGYAGMEEKVRKYLFKILID"
     gene            9183..9461
                     /locus_tag="ACL3EZ_001436"
     CDS             9183..9461
                     /locus_tag="ACL3EZ_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000118489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0392987.1"
                     /translation="MAWIIRGIVNALIGRYIKLGTYAAKYGISMARSILSRAAATAAA
                     RVGLSTKISGWILRVAVNVADVYGNFANNIAAAWDAHDKIPNNGRINF"
     gene            9471..9665
                     /locus_tag="ACL3EZ_001437"
     CDS             9471..9665
                     /locus_tag="ACL3EZ_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0392988.1"
                     /translation="MKALCIFLLNMLAWTVLAMIIRGGLDGFNEHTWSTILIASLSGI
                     YIDYMSIDKSRKKSKRKKKK"
     gene            9748..10392
                     /locus_tag="ACL3EZ_001438"
     CDS             9748..10392
                     /locus_tag="ACL3EZ_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HGR0392989.1"
                     /translation="MAQKGVSLIKAAFDTDNFLMRFSEKVLDIVTANLLFVVSCLPIV
                     TIGVAKISLYETMFEVKKSRRVPVFKIYLRSFKQNLKLGLQLGLMELGIVFLTLSDLY
                     LFWGQTALPFQLLKAICLGILIFLTIVMLASYPIAARYDLSWKEILQKGLMLASFNFP
                     WFFLMLAILVLIVMVLYLSAFSLLLGGSVFLLFGFGLLVFIQTGLMEKIFAKYQ"
     gene            10561..11478
                     /locus_tag="ACL3EZ_001439"
     CDS             10561..11478
                     /locus_tag="ACL3EZ_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016829 - lyase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HGR0392990.1"
                     /translation="MSDLKKYEGVIPAFYACYDDQGEVSPERTRALVQYFIDKGVQGL
                     YVNGSSGECIYQSVEDRKLILEEVMAVAKGKLTIIAHVACNNTKDSMELARHAESLGV
                     DAIATIPPIYFRLPEYSVAKYWNDISSAAPNTDYVIYNIPQLAGVALTPSLYTEILKN
                     PRVIGVKNSSMPVQDIQTFVSLGGEDHIVFNGPDEQFLGGRLMGAKAGIGGTYGAMPE
                     LFLKLNQLIADKDLETARELQYAINAIIGKLTSAHGNMYGVIKEVLKINEGLNIGSVR
                     SPLTPVIEEDRPVVEAAAALIRETKERFL"
     gene            11496..12380
                     /locus_tag="ACL3EZ_001440"
     CDS             11496..12380
                     /locus_tag="ACL3EZ_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HGR0392991.1"
                     /translation="MTYYVAIDIGGTNIKYGLVDQEGQLLESHEMPTEAHKGGPHILQ
                     KTKDIVASYLEKGPVAGVAISSAGMVDPDKGEIFYAGPQIPNYAGTQFKKEIEESFTI
                     PCEIENDVNCAGLAEAVSGSGKGASVTLCLTIGTGIGGCLIMDRKVFHGFSNSACEVG
                     YMHMQDGAFQDLASTTALVKYVAEAHGEDVDQWNGRRIFKEATEGNKICMEGIDRMVD
                     YLGKGLANICYVANPEVVILGGGIMGQEAILKPKIRTALKEALVPSLAEKTRLEFAHH
                     QNTAGMLGAYYHFKTKQS"
     gene            complement(12396..13247)
                     /locus_tag="ACL3EZ_001441"
     CDS             complement(12396..13247)
                     /locus_tag="ACL3EZ_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HGR0392992.1"
                     /translation="MDKPDIATIIDSHFEEMTDLEQEIARYFLQAETITDDLSSQQVT
                     QKLHISQAALTRFAKKCGFTGYREFIFQYQHQAENQANQVSKHSPLTKRVLRSYSNMR
                     EQTQDLIDEIQLERIAQLIEDAERIYFFGTGSSGLVAREMKLRFMRLGVVCEALTDQD
                     GFAWTTSIMDENCLVLGFSLSGSTPSILDSLLDAKEMGAKTVLFTSVPNKDSQTYTET
                     VLVATHSQPSYIQRISAQLPMLFFIDLIYAYFLEINRESKEKIFNSYWENKKLNGYRR
                     QKRVRKS"
     gene            13447..15504
                     /gene="pbp2b"
                     /locus_tag="ACL3EZ_001442"
     CDS             13447..15504
                     /gene="pbp2b"
                     /locus_tag="ACL3EZ_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2B"
                     /protein_id="HGR0392993.1"
                     /translation="MRLICMRKFNSHSIPIRLNLLFSIVILLFMTIIGRLLYMQVLNK
                     DFYEKKLASASQTKITSSSARGEIYDASGKPLVENTLKQVVSFTRSNKMTATDLKETA
                     KKLLTYVSISSPNLTERQLADYYLADPEIYKKTVEALPSEKRLDSDGNRLSESELYNN
                     AVDSVQTSQLNYTEDEKKEIYLFSQLNAVGNFATGTIATDPLNDSQVAVIASISKELP
                     GISISTSWDRKVLETSLSSIVGSVSSEKAGLPAEEAEAYLKKGYSLNDRVGTSYLEKQ
                     YEETLQGKRSVKEIHLDKYGNMESVDTIEEGSKGNNIKLTIDLAFQDSVDALLKSYFN
                     SELENGGAKYSEGVYAVALNPKTGAVLSMSGIKHDLKTGELTPDSLGTVTNVFVPGSV
                     VKAATISSGWENGVLSGNQTLTDQSIVFQGSAPINSWYTQAYGSFPITAVQALEYSSN
                     TYMVQTALGLMGQTYQPNMFVGTSNLESAMEKLRSTFGEYGLGTATGIDLPDESTGFV
                     PKEYSFANYITNAFGQFDNYTPMQLAQYVATIANNGVRVAPRIVEGIYGNNDKGGLGD
                     LIQQLQPTEMNKVNISDSDMSILHQGFYQVAHGTSGLTTGRAFSNGALVSISGKTGTA
                     ESYVADGQQATNTNAVAYAPSDNPQIAVAVVFPHNTNLTNGVGPSIARDIINLYQKYH
                     PMN"
     gene            15515..16111
                     /gene="recR"
                     /locus_tag="ACL3EZ_001443"
     CDS             15515..16111
                     /gene="recR"
                     /locus_tag="ACL3EZ_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombination mediator RecR"
                     /protein_id="HGR0392994.1"
                     /translation="MLYPTPIAKLIDSYSKLPGIGIKTATRLAFYTIGMSADDVNEFA
                     KNLLSAKRELTYCSICGRLTDDDPCSICTDPTRDQTTILVLEDSRDVAAMENIQEYHG
                     LYHVLHGLISPMNGISPDDINLKSLMTRLMDSEVSEVIVATNATADGEATSMYLSRLL
                     KPAGIKVTRLARGLAVGADIEYADEVTLLRAIENRTEL"
     gene            16287..17330
                     /locus_tag="ACL3EZ_001444"
     CDS             16287..17330
                     /locus_tag="ACL3EZ_001444"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HGR0392995.1"
                     /translation="MKQTIILLYGGRSAEREVSVLSAESVMRAVNYDRFTVKTFFISQ
                     SGDFIKTQEFSHAPGQEDRLMTNETIDWDKKVAPSAIYEEGAVVFPVLHGPMGEDGSV
                     QGFLEVLKMPYVGCNILSSSLAMDKITTKRVLESAGIAQVPYVAIVEGDDVTAKIAEV
                     EEKLAYPVFTKPSNMGSSVGISKSENQEELRQALKLAFRYDSRVLVEQGVNAREIEVG
                     LLGNYDVKSTLPGEVVKDVAFYDYDAKYIDNKITMDIPAKISDDVVAVMRQNAETAFR
                     AIGGLGLSRCDFFYTDKGEIFLNELNTMPGFTQWSMYPLLWDNMGISYPGLIERLVDL
                     AKESFDKREAHLI"
     gene            17414..18787
                     /gene="murF"
                     /locus_tag="ACL3EZ_001445"
     CDS             17414..18787
                     /gene="murF"
                     /locus_tag="ACL3EZ_001445"
                     /EC_number="6.3.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0047480 -
                     UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase
                     activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HGR0392996.1"
                     /translation="MKLTIHEIAQVVGAKNDISIFEDTQLEKAEFDSRLIGTGDLFVP
                     LKGARDGHDFIETAFENGAAVTLSEKEVSNHPYILVDDVLTAFQSLASYYLEKTTVDV
                     FAVTGSNGKTTTKDMLAHLLSTRYKTYKTQGNYNNEIGLPYTVLHMPEGTEKLVLEMG
                     QDHLGDIHLLSELARPKTAIVTLVGEAHLAFFKDRSEIAKGKMQIADGMASGSLLLAP
                     ADPIVEDYLPTDKKVVRFGQGAELEITDLVERKDSLTFKANFLEQALDLPVTGKYNAT
                     NAMIASYVALQEGVSEEQIRLAFQDLELTRNRTEWKKAANGADILSDVYNANPTAMKL
                     ILETFSAIPANEGGKKIAVLADMKELGDQSVQLHNQMILSLSPDVLDTVIFYGQDIAQ
                     LAQLASQMFPIGHVYYFKKTEDQDQFEDLVKQVKESLGAHDQILLKGSNSMNLAKLVE
                     SLENEDK"
     gene            18774..19385
                     /locus_tag="ACL3EZ_001446"
     CDS             18774..19385
                     /locus_tag="ACL3EZ_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase N-terminal domain-containing
                     protein"
                     /protein_id="HGR0392997.1"
                     /translation="MKTSDFVKYLQRMIAITDTGLTFTKDPFDRERYEDLRSLLSEML
                     NQASDLDSEEVAEVLKPTSAYATPLMDVRAWIVEDEKICLVRGQGEDSWALPGGFGEV
                     GYSPTENILKEIEEETGFKAKVERLLAVFDTNRFQLQSKQYTKFVFGCKLLDGQFQEN
                     QEIADLQFFAIDQLPNLSEKRITKEQIELLWQVYQGHRGQYLD"
     gene            19476..20180
                     /locus_tag="ACL3EZ_001447"
     CDS             19476..20180
                     /locus_tag="ACL3EZ_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001055242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02206 family membrane protein"
                     /protein_id="HGR0392998.1"
                     /translation="MNLWDIFFTTQATEPPKFDLFWYVSLFTLLALTFYTAHRYREKK
                     VYQRFFQILQTVQLILLYGWYWVNHMPLSESLPFYHCRMAMFVVLLLPGQSKYKQYFA
                     LLGTFGTLAAFVYPVPDAYPFPHITILSFIFGHLALLGNSLVYLLRQYNARLLDVKGI
                     FLMTFALNALIFVVNLVTGGDYGFLTKPPLVGDHGLVANYLLVSIVLVATISLTKKIL
                     EFFLAQEAEKMIAKEA"
     gene            20399..21772
                     /gene="ftsA"
                     /locus_tag="ACL3EZ_001448"
     CDS             20399..21772
                     /gene="ftsA"
                     /locus_tag="ACL3EZ_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0043093 - FtsZ-dependent cytokinesis
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HGR0392999.1"
                     /translation="MAREGFFTGLDIGTSSVKVLVAEQRNGELNVIGVSNAKSKGVKD
                     GIIVDIDAAATAIKSAISQAEEKAGISIKSVNVGLPGNLLQVEPTQGMIPVTSDTKEI
                     TDQDVENVVKSALTKSMTPDREVITFIPEEFIVDGFQGIRDPRGMMGVRLEMRGLLYT
                     GPRTILHNLRKTVERAGVQVENVIISPLAMVQSVLNEGEREFGATVIDMGAGQTTVAT
                     IRNQELQFTHILQEGGDYVTKDISKVLKTSRKLAEGLKLNYGEAYPPLASKETFQVEV
                     IGEVEAVEVTEAYLSEIISARIKHILEQIKQELDRRRLLDLPGGIVLIGGNAILPGMV
                     ELAQEVFGVRVKLYVPNQVGIRNPAFAHVISLSEFAGQLTEVNLLAQGAIKGENDLSH
                     QPISFGGMLQKTAQFVQSTPVQPAPAPEVEPVAPTEPMADFQQASQNKPKLADRFRGL
                     IGSMFDE"
     gene            21789..23048
                     /gene="ftsZ"
                     /locus_tag="ACL3EZ_001449"
     CDS             21789..23048
                     /gene="ftsZ"
                     /locus_tag="ACL3EZ_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000144288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HGR0393000.1"
                     /translation="MTFSFDTAAAQGAVIKVIGVGGGGGNAINRMVDEGVTGVEFIAA
                     NTDVQALSSTKAETVIQLGPKLTRGLGAGGQPEVGRKAAEESEETLTEAISGADMVFI
                     TAGMGGGSGTGAAPVIARIAKDLGALTVGVVTRPFGFEGSKRGQFAVEGINQLREHVD
                     TLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITNPGLINLDFADVKTV
                     MANKGNALMGIGIGSGEERVVEAARKAIYSPLLETTIDGAEDVIVNVTGGLDLTLIEA
                     EEASQIVNQAAGQGVNIWLGTSIDESMRDEIRVTVVATGVRQDRVEKVVAPQARSATN
                     YRETVKPAHSHGFDRHFDMAETVELPKQNPRRLEPTQASAFGDWDLRRESIVRTTDSV
                     VSPVERFEAPISQDEDELDTPPFFKNR"
     gene            23053..23724
                     /locus_tag="ACL3EZ_001450"
     CDS             23053..23724
                     /locus_tag="ACL3EZ_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HGR0393001.1"
                     /translation="MNVKENTELVFREVAEASLSAHRESGSVSVIAVTKYVDVPTAEA
                     LLPLGVHHIGENRVDKFLEKYEALKDRDVTWHLIGTLQRRKVKDVIQYVDYFHALDSV
                     KLAGEIQKRSDRVIKCFLQVNISKEESKHGFSREELLEILPELARLDKIEYVGLMTMA
                     PFEASSEQLKEIFKAAQDLQREIQEKQIPNMPMTELSMGMSRDYKEAIQFGSTFVRIG
                     TSFFK"
     gene            23734..24273
                     /locus_tag="ACL3EZ_001451"
     CDS             23734..24273
                     /locus_tag="ACL3EZ_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HGR0393002.1"
                     /translation="MSLKDRFDRFIDYFTEDEDSSLPYEKRDEPVFTSVNSSQEPALP
                     MNQPSQSAGTKENNITRLHARQQELANQSQRATDKVIIDVRYPRKYEDATEIVDLLAG
                     NESILIDFQYMTEVQARRCLDYLDGACHVLAGNLKKVASTMYLLTPVNVIVNVEDIRL
                     PDEDQQGEFGFDMKRNRVR"
     gene            24273..24536
                     /locus_tag="ACL3EZ_001452"
     CDS             24273..24536
                     /locus_tag="ACL3EZ_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HGR0393003.1"
                     /translation="MIFLIRMIYNAVDIYSLILVAFAVMSWFPGAYESSLGRWIVALV
                     KPVLAPLQRLPLQIAGLDLSVWVAIVLVRFLGENLVRFLAMIG"
     gene            24533..25318
                     /locus_tag="ACL3EZ_001453"
     CDS             24533..25318
                     /locus_tag="ACL3EZ_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HGR0393004.1"
                     /translation="MNKGIYQHFSIEDRPFLDKGMEWIKKVEDSYAPFLTPFINPHQE
                     KLLKILAKTYGLACSSSGEFVSSEYVRVLLYPDYFQPEFSDFEISLQEIVYSNKFEYL
                     THAKILGTVINQLGIERKLFGDILVDEERAQIMINQQFLLLFQDGLKKIGRIPVSLEE
                     RPFTEKIDKLEQYRELDLSVSSFRLDVLLSNVLKLSRNQANQLIEKKLVQVNYHVVDK
                     SDYTVQVGDLISVRKFGRLRLLQDKGQTKKEKKKITVQLLLSK"
     gene            25327..26115
                     /gene="divIVA"
                     /locus_tag="ACL3EZ_001454"
     CDS             25327..26115
                     /gene="divIVA"
                     /locus_tag="ACL3EZ_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIVA"
                     /protein_id="HGR0393005.1"
                     /translation="MPITSLEIKDKTFGTRFRGFDPEEVDEFLDIVVRDYEDLVRANH
                     DKNLRIKSLEERLSYFDEIKDSLSQSVLIAQDTAERVKQAAHERSNNIIHQAEQDAQR
                     LLEEAKYKANEILRQATDNAKKVAVETEELKNKSRVFHQRLKSTIESQLAIVESSDWE
                     DILRPTATYLQTSDEAFKEVVSEVLGEPIPAPIEEEPIDMTRQFSQAEMEELQARIEV
                     ADKELSEFEAQIKQEVETPTPVVSPQVEEEPLLIQLAQCMKNQK"
     gene            26463..29255
                     /gene="ileS"
                     /locus_tag="ACL3EZ_001455"
     CDS             26463..29255
                     /gene="ileS"
                     /locus_tag="ACL3EZ_001455"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004822 - isoleucine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006428 - isoleucyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HGR0393006.1"
                     /translation="MKLKDTLNLGKTEFPMRAGLPTKEPVWQKEWEDAKLYQRRQELN
                     QGKPHFTLHDGPPYANGNIHVGHAMNKISKDIIVRSKSMSGFYAPFIPGWDTHGLPIE
                     QVLSKQGVKRKEMDLVEYLKLCREYALSQVDKQREDFKRLGVSGDWENPYVTLTPDYE
                     AAQIRVFGEMANKGYIYRGAKPVYWSWSSESALAEAEIEYHDLVSTSLYYANKVKDGK
                     GVLDTDTYIVVWTTTPFTITASRGLTVGADIDYVLVQPVGEARKFVVAAELLTSLSEK
                     FGWADVQVLETYRGQELNHIVTEHPWDTAVEELVILGDHVTTDSGTGIVHTAPGFGED
                     DYNVGIANNLEVAVTVDERGIMMKNAGPEFEGQFYEKVVPTVIEKLGNLLLAQEEISH
                     SYPFDWRTKKPIIWRAVPQWFASVSKFRQEILDEIEKVKFHSEWGKVRLYNMIRDRGD
                     WVISRQRAWGVPLPIFYAEDGTAIMVAETIEHVAQLFEEHGSSIWWERDAKDLLPEGF
                     THPGSPNGEFKKETDIMDVWFDSGSSWNGVVVNRPELTYPADLYLEGSDQYRGWFNSS
                     LITSVANHGVAPYKQILSQGFALDGKGEKMSKSLGNTIAPSDVEKQFGAEILRLWVTS
                     VDSSNDVRISMDILSQVSETYRKIRNTLRFLIANTSDFNPAQDTVAYDELRSVDKYMT
                     ICFNQLVKTIRDAYADFEFLTIYKALVNFINVDLSAFYLDFAKDVVYIEGAKSLERRQ
                     MQTVFYDILVKITKLLTPILPHTAEEIWSYLEFETEDFVQLSELPEAQTFANQEEILD
                     TWAAFMDFRGQAQKALEEARNAKVIGKSLEAHLTVYPNEVVKTLLEAVNSNVAQLLIV
                     SELTIAEGPAPEAALSFEDVAFTVERAAGEVCDRCRRIDPTTAERSYQAVICDHCASI
                     VEENFAEAVAEGFEEK"
BASE COUNT         8950 a         5302 c         6518 g         8714 t
ORIGIN      
        1 gtagtggaag agttctatca agtattgatg cacgttatgg tgggactcat gattctaaaa
       61 gtaagattaa tattgccact tcttatagtg atgataatgg gaaaacgtgg agtgagccaa
      121 tttttgctat gaagtttaat gactatgagg agcagttagt ttactggcca cgagataata
      181 aattaaagaa tagtcaaatt agtggaagtg cttcattcat agattcatcc attgttgaag
      241 ataaaaaatc tgggaaaacg atattactag ctgatgttat gcctgcgggt attggaaata
      301 ataatgcaaa taaagccgac tcaggtttta aagaaataaa tggtcattat tatttaaaac
      361 taaagaagaa tggagataac gatttccgtt atacagttag agaaaatggt gtcgtttatg
      421 atgaaacaac taataaacct acaaattata ctataaatga taagtatgaa gttttggagg
      481 gaggaaagtc tttaacagtc gaacaatatt cggttgattt tgatagtggc tctttaagag
      541 aaaaacataa tggaaaacag gtccctatga atgttttcta caaagattcg ttatttaaag
      601 tgactcctac taattatata gcaatgacaa ctagtcagaa tagaggagag agttgggaac
      661 aatttaagtt gttgcctccg ttcttaggag aaaaacataa tggaacttac ttatgtcccg
      721 gacaaggttt agcattaaaa tcaagtaaca gattgatttt tgcaacatat actagtggag
      781 aactaaccta tctcatttct gatgatagtg gtcaaacatg gaagaaatcc tcagcttcaa
      841 ttccgtttaa aaatgcaaca gcagaagcac aaatggttga actgagagat ggtgtgatta
      901 gaacattctt tagaaccact acaggtaaga tagcttatat gactagtaga gattctggag
      961 aaacatggtc gaaagtttcg tatattgatg gaatccaaca aacttcatat ggcacacaag
     1021 tatctgcaat taaatactct caattaattg atggaaaaga agcagtcatt ttgagtacac
     1081 caaattctag aagtggccgt aagggaggtc aattagttgt tggtttagtc aataaagaag
     1141 atgatagtat tgattggaaa taccactatg atattgattt gccttcgtat ggttatgcct
     1201 attctgcgat tacagaattg ccaaatcatc acataggtgt gctgtttgaa aaatatgatt
     1261 cgtggtcgag aaatgaattg catttaagca atgtagttca gtatatagat ttggaaatta
     1321 atgatttaac aaaataaagg agaaaaaaca tggttaaata cggtgttgtt ggagcagggt
     1381 attttggagc tgaattggct cgctacatgc aaaagaatga tggagcagag attactcttc
     1441 tctatgatcc agataatgca gaggcgattg cagaagaatt gggagcaaaa gtagcaagtt
     1501 ccttagatga gttggtttct agcgatgaag tagattgtgt tatcgtcgca actccaaata
     1561 atcttcataa ggaaccggtt attaaggctg cacagcatgg taaaaatgtt ttctgtgaaa
     1621 aaccaattgc gctttcttat caagattgtc gcgagatggt agatgcgtgt aaagaaaaca
     1681 atgtaacctt tatggcagga catattatga atttctttaa tggtgttcat catgcaaaag
     1741 aactcattaa tcaaggagtt atcggagacg ttctatattg tcatacagct cgtaatggtt
     1801 gggaagaaca acaaccgtca gtatcatgga aaaaaattcg tgaaaaatca ggtggtcact
     1861 tgtatcacca catccatgaa ttggattgcg ttcaattcct tatggggggc atgcctgaaa
     1921 ctgtaaccat gacaggtgga aatgtggccc atgaaggtga acatttcggt gatgaagatg
     1981 atatgatttt tgtcaatatg gaattttcta ataagcgttt tgccttgtta gaatggggtt
     2041 cagcttatcg ttggggtgaa cattatgtct taatccaagg aagcaaaggt gccatccgct
     2101 tagacttatt caactgtaaa ggaactctta agctagatgg gcaagaaagc tatttcttga
     2161 ttcacgaatc gcaagaagaa gatgatgatc ggactcgtat ctatcatagt acagagatgg
     2221 atggagcaat tgcttatggt aaaccaggta aacgtactcc attatggcta tcatctgtca
     2281 ttgataaaga aatgcgctat ctgcatgaga ttatggaagg agccccagta tcagaagaat
     2341 ttgcaaaact tttgacaggt gaagctgccc tagaagcaat tgctactgca gatgcttgta
     2401 cccagtctat gtttgaagat cgcaaagtaa aattgtcaga aattgtaaaa taaattttgg
     2461 tattctccta tttataggtc gacttgctcc tctgaaagta cttttagagg agctgtttga
     2521 ctttgctagt ttttgaaact gaaatctatt atactacaaa ctattgaaag cgttttaatt
     2581 ttaaggtata ataatctcat agaaataaag aaaaggagga aagaggatgc cacagattag
     2641 caaagaagcc ttgattgagc aaatcaaaga tggaatcatc gtttcttgtc aggctcttcc
     2701 tcatgaaccg ctttatacag aagcgggagg ggtgattccc ttgctggtca aagcggctga
     2761 gcaaggtgga gcagtcggta tccgagcaaa cagtgttcgc gatatcaagg aaattaagga
     2821 agtcactaaa cttccaatca ttgggattat caaacgtgat tatccacctc aggaaccctt
     2881 catcacggct actatgaaag aagttgatga attggcagaa ctggacatcg aggtgattgc
     2941 tctggattgt accaagcgtg aacgctacga tggtttggaa attcaagagt tcattcgtca
     3001 ggttaaggag aaatatccta atcagctttt gatggctgat actagtatct tcgaagaagg
     3061 gctagcagct gtagaagcag gaattgactt tgtcggaaca accttatcag gctacacatc
     3121 ctacagtcca aaagtagacg gtccagattt tgaattgatt aagaaactct gtgatgccgg
     3181 tgtagatgtc attgcagaag gaaaaattca tacaccagaa caagccaaac aaatccttga
     3241 atatggagtg cgaggcatcg ttgttggtgg cgccattact agaccaaaag agattacaga
     3301 acgcttcgtt gctagtctta aataagatgt gagagggagt tttatgttta aagttttaca
     3361 aaaagttgga aaagctttta tgttacctat agctatactt cctgcagcag gtctactttt
     3421 ggggattggt ggtgcacttt caaacccaac cacgatagca acttatccaa tactagacaa
     3481 tagtattttt caatcaatat tccaagtaat gagctctgca ggagaggttg tattcagtaa
     3541 tttgtcacta cttctctgtg tgggattatg tattggctta gcgaaacgag ataaaggaac
     3601 cgctgcgtta gcaggagtaa ctggttactt agttatgact gcaacgatca aagctttggt
     3661 aaaacttttt atggcagaag gatctgcaat tgatactgga gttattggag cattagttgt
     3721 cggaatagtt gccgtatatt tgcacaaccg atataacaat attcaattac cttccgcttt
     3781 aggattcttt ggaggttcac gcttcgttcc tattgttaca tcgttctctt ctatcttgat
     3841 tggctttgtc ttctttgtta tttggccacc tttccaacaa cttcttgttt ctacaggtgg
     3901 atatatttct caggcgggtc caattggaac ttttctatat ggatttttaa tgagactttc
     3961 tggagcagta ggcttacatc atataattta ccctatgttt tggtatactg aacttggtgg
     4021 tgttgaaact gttgcaggac aaacagtggt tggagctcaa aaaatatttt ttgctcaatt
     4081 agccgatccg gcccattctg gattatttac agaaggaaca aggttttttg caggtcgttt
     4141 ctcaacaatg atgttcggtt taccggctgc ctgtttagcg atgtaccata gtgttcctaa
     4201 aaatcgtcgt aaaaaatacg cgggtttgtt ttttggagtt gctttaacat cttttattac
     4261 cggtattaca gaaccaattg aatttatgtt tctattcgtc agtccggttc tatatgttgt
     4321 tcacgcattc cttgatggtg ttagcttctt tattgcagac gtcttaaata tttcaatagg
     4381 aaacacattt tcaggaggtg taatcgattt cactttattt ggaattttgc aggggaacgc
     4441 taagacgaat tgggttcttc agattccaat tggacttatt tggagtgttt tgtattatat
     4501 tatttttaga tggttcatta ctcaattcaa cgttctaacg ccaggacgag gagaagaagt
     4561 agattctaaa gaaatttctg aatccgcaga ttcaacttca aatactgcag attatttaaa
     4621 acaggatagc ctacaaatta tcagagcctt gggtggatca aataatatag aagatgtaga
     4681 tgcttgtgtg acacgtttac gtgtagctgt aaaagaagtt aatcaagttg ataaagcact
     4741 tttaaaacaa attggtgcag ttgatgtctt agaagtgaag ggtggcattc aagcaatcta
     4801 tggagcaaaa gcaatcttat ataaaaatag tattaatgaa attttaggtg tagatgatta
     4861 agtacttact gacttaataa aaaacagagg agagtgatgg atgagtagga tgaaatgaaa
     4921 tcgtatacaa gaaataaaga actcattatc caagttggat acgcttatta cataggagaa
     4981 tacaaatgaa atttagaaaa ttagcttgta cagtacttgc gggtgctgcg gttcttggtc
     5041 ttgctgcttg tggcaattct ggcggaagta aagatgctgc caaatcaggt ggtgacggtg
     5101 ccaaaacaga aatcacttgg tgggcattcc cagtatttac ccaagaaaaa actggtgacg
     5161 gtgttggaac ttatgaaaaa tcaatcatcg aagcgtttga aaaagcaaac ccagatataa
     5221 aagtgaaatt ggaaaccatc gacttcaagt caggtcctga aaaaatcaca acagccatcg
     5281 aagcaggaac agctccagac gtactctttg atgcaccagg acgtatcatc caatacggta
     5341 aaaacggtaa attggctgag ttgaacgacc tcttcacaga tgaatttgtt aaagatgtca
     5401 acaatgaaaa catcgtacaa gcaagtaaag ctggagacaa ggcttatatg tatccgatta
     5461 gttctgcccc attctacatg gcaatgaaca agaaaatgtt agaagatgct ggagtagcaa
     5521 accttgtaaa agaaggttgg acaactgatg attttgaaaa agtattgaaa gcacttaaag
     5581 acaagggtta cacaccaggt tcattgttca gttctggtca agggggagac caaggaacac
     5641 gtgcctttat ctctaacctt tatagcggtt ctgtaacaga tgaaaaagtt agcaaatata
     5701 caactgatga tcctaaattc gtcaaaggtc ttgaaaaagc aactagctgg attaaagaca
     5761 atttgatcaa taatggttca caatttgacg gtggggcaga tatccaaaac tttgccaacg
     5821 gtcaaacatc ttacacaatc ctttgggcac cagctcaaaa tggtatccaa gctaaacttt
     5881 tagaagcaag taaggtagaa gtggtagaag taccattccc atcagacgaa ggtaagccag
     5941 ctcttgaata ccttgtaaac gggtttgcag tattcaacaa taaagacgac aagaaagtcg
     6001 ctgcatctaa gaaattcatc cagtttatcg cagatgacaa ggagtgggga cctaaagacg
     6061 tagttcgtac aggtgctttc ccagtccgta cttcatttgg aaaactttat gaagacaaac
     6121 gcatggaaac aatcagcggc tggactcaat actactcacc atactacaac actattgatg
     6181 gatttgctga aatgagaaca ctttggttcc caatgttgca atctgtatca aatggtgacg
     6241 aaaaaccagc ggatgctttg aaagccttca ctgaaaaagc aaacgaaaca atcaaaaaag
     6301 ctatgaaaca atagttctta gttattctat aaaaagtagt tttttaaaga acctaagagt
     6361 gtataccccc ttttccctct acacagatag tgtaagaaaa gggggctttt gtttaaaatg
     6421 taagaaactg tcacgaaatt aaaatgaagt tcttacataa gcgaatcata aaaaatttca
     6481 ttttgatttt aaaacagttc aagaaagtca aaaaattatt ctatttgaaa gagaggtgcc
     6541 gactgtgaaa gtcaataaaa tccgtatgcg ggaaacagtg atttcctacg ctttcctagc
     6601 accagtatta ttcttctttg tcatctttgt gttggctccg atggtgatgg gcttcattac
     6661 aagtttcttt aactactcaa tgactaaatt tgagtttgta ggcttggata actatatccg
     6721 tatgtttaaa gatcctgtct ttacaaaatc tctgattaac acagttattt tggttattgg
     6781 atctgtacca gttgttgttc tattctcact ctttgtagca tctcagacct atcatcaaaa
     6841 tgtcattgcc agatccttct accgtttcgt cttcttcctt cctgttgtaa cgggtagtgt
     6901 tgccgtgaca gttgtttgga aatggattta tgacccacta tcagggattc taaactttgt
     6961 ccttaagtcc agccacatca tcagccaaaa catttcttgg ttgggagata aaaactgggc
     7021 attgatggcg attatgatta ttctcttgac cacttcagtt ggtcagccca tcatccttta
     7081 tatcgctgcc atggggaata ttgacaattc actggttgaa gcggcgcgtg ttgatggtgc
     7141 aactgagttt caagtttttt ggaagattaa atggccaagc cttcttccaa caactcttta
     7201 tattgcaatc atcacaacaa ttaactcatt ccagtgtttc gccttgattc agcttttgac
     7261 atctggtggt ccaaactact caacaagtac cttgatgtac tacctttacg aaaaagcctt
     7321 ccaattgaca gaatacggct atgccaacac aattggtgtc ttcttggcag tcatgattgc
     7381 tatcgtaagc tttgttcaat ttaaagtact tggaaacgac gtagaatact aaagaaagga
     7441 gacagctatg caatctacag aaaaaaaacc attaacagcc tttactgtta tttcaacaat
     7501 cattttgctc ttgttgactg tgctgttcat ctttccattc tactggattt tgacaggggc
     7561 attcaaatca caacctgata caattgttat tcctcctcag tggttcccta aaatgccaac
     7621 catggaaaac ttccaacaac tcatggtgca gaaccctgcc ttgcaatgga tgtggaactc
     7681 agtatttatc tcattggtaa ccatgttctt agtttgtgca acctcatctc tagcaggtta
     7741 tgtattggct aaaaaacgtt tctatggtca acgcattcta tttgctatct ttatcgctgc
     7801 tatggcgctt ccaaaacaag ttgtccttgt accattggta cgtatcgtca acttcatggg
     7861 aatccacgat actctctggg cagttatctt gcctttgatt ggatggccat tcggtgtctt
     7921 cctcatgaaa caatttagtg aaaatattcc tacagagttg cttgaatcag ctaaaatcga
     7981 cggttgtggt gagattcgta ccttctggag tgtagccttc ccgattgtga aaccagggtt
     8041 tgcagccctt gcaatcttta ccttcatcaa tacttggaat gactacttca tgcaattggt
     8101 aatgttgact tcacgtaaca atttgaccat ctcacttggg gttgcgacca tgcaggctga
     8161 aatggcaacc aactatggtt tgattatggc aggagctgcc cttgctgctg ttccaatcgt
     8221 cacagtcttc cttgtcttcc aaaaatcctt cacacagggt attactatgg gagcggtcaa
     8281 aggataatac tctgcgaaaa tctcttcaaa ctacgtcagc ttcaccttgc catacttaag
     8341 tattgcctgc ggttagcttc ctagtttgtt cttcaatttt cattgagtat aggaaaatca
     8401 atctatcaag atacagaagt atattttata gatttagaga atatagaggt tataagtgtc
     8461 tacaaaatgg agggtatgca gttactttat gaagttttgt cagacactta taaacttaag
     8521 aatggtttta gttaactatc agaaacgaag gaaagagtat gatttttgac gatttgaaaa
     8581 acatcacctt ttacaaaggg attcatccta atttagacaa ggctatcgac tatctctacc
     8641 aacatcgtaa ggattctttc gaattaggaa agtatgatat tgatggagat aaagtctttc
     8701 tagttgttca ggaaaatgtc ctcaatcaag ctgaaaatga tcaatttgag tatcataaga
     8761 actatgcaga tttgcatttg ctggtagaag gacatgaata ttcgagctac ggttcacgta
     8821 tcaaagacga ggcagtagca ttcgacgaag cgagtgacat tggctttgtt cattgtcatg
     8881 aacactaccc actcttgttg ggttatcaca attttgcgat tttcttccca ggtgagccac
     8941 atcagccaaa tggttatgca ggcatggaag aaaaggttcg aaaatatctc tttaaaattt
     9001 tgattgatta aaaataggat gaattgtttt tttgtaaagc tttgataata ctctaccatg
     9061 aaattgatct ttgtgaggta gagaaatgag aataaaatat ttaaaaattg gtatcttctt
     9121 gtcagtctgt gtatgctaca agagctagtt tcttggatgg acagggaatt acagttgatg
     9181 agatggcttg gataattagg ggcattgtga atgcattgat tggtagatac ataaaattag
     9241 gtacttatgc ggctaagtat ggtattagta tggcacgctc gatcttaagt agggcagctg
     9301 caactgcagc agcaagagta ggattatcga ccaagatttc tggatggatt ttacgagtag
     9361 ctgtgaatgt agctgatgta tatggtaatt ttgccaacaa tattgctgca gcttgggatg
     9421 cacatgataa aatccctaac aatggtcgta taaactttta aaatgcgaga atgaaagcac
     9481 tttgtatttt tttattgaat atgttagctt ggacagtgct tgcaatgata attcgtggag
     9541 ggctagatgg atttaatgag catacttgga gtactatttt aattgcttcg ctgtccggga
     9601 tatatataga ttatatgtcc atagataaaa gtagaaaaaa gtccaaaaga aaaaagaaaa
     9661 aatagatttg ttcatggtag ggacttatga aagttttact gacaaaaaag aaaacagttt
     9721 acaaagaaaa atgatggagg agcaaacatg gcacaaaaag gagtaagcct tatcaaggca
     9781 gcatttgata cagataactt tctcatgcgt tttagtgaga aagtcttgga catcgtgaca
     9841 gccaatcttc tttttgtcgt ctcttgtttg cccatcgtga cgattggagt ggctaaaatc
     9901 agcctctacg agaccatgtt cgaagttaag aagagcagac gggtgcctgt ttttaaaatc
     9961 tatctaagat ctttcaagca aaatctgaaa ctaggtcttc agctgggttt aatggagtta
    10021 ggaattgtgt ttcttaccct ttcagatctc tatcttttct ggggtcaaac agctctgccc
    10081 ttccaattgc tgaaagccat ttgtttaggt attctgattt ttcttactat cgtgatgctg
    10141 gctagttacc ctatcgcggc acgttatgac ctatcttgga aagaaattct tcaaaaagga
    10201 ttgatgttgg ctagttttaa ctttccttgg ttcttcctca tgttagccat tcttgtcctc
    10261 attgtgatgg ttctttatct gtccgccttc agtctactct taggtggctc agtcttccta
    10321 ctttttgggt ttggactatt ggtctttatc cagactggat tgatggagaa aattttcgca
    10381 aaataccaat aggagcttta tttctgaaac tactttcaaa ggctccaaac gctattctat
    10441 aagcgagaaa ctaaaatcta agtgtctata agatattgaa agccttttcg gtaaagtgta
    10501 tactaaagaa gtaaagaaaa atctgcttta gcagaaaata aaaataatag gagaaaatct
    10561 atgtcagatt tgaaaaaata cgaaggtgtc attccagcct tctacgcatg ttatgatgat
    10621 caaggagaag taagcccaga acgtacgcgt gccttggttc aatacttcat tgataaaggt
    10681 gttcaaggtc tttatgtcaa tggttcttct ggtgaatgta tctaccaaag cgttgaagat
    10741 cgcaagttga ttttggaaga agtcatggcg gtagccaaag gtaaattgac cattattgcc
    10801 catgttgctt gcaataatac taaagatagt atggaacttg ctcgccatgc tgaaagcttg
    10861 ggagtagatg ctattgcaac gattccacca atttatttcc gcttgccaga atactcagtt
    10921 gccaaatact ggaacgatat cagttctgca gctccaaaca cagactacgt gatttacaac
    10981 attcctcaat tggcaggggt tgctttgact ccaagccttt acacagaaat attgaaaaat
    11041 cctcgtgtta tcggtgtgaa gaactcttct atgccagttc aagatatcca aacctttgtc
    11101 agccttggtg gagaagacca tatcgtcttt aatggtcctg atgagcagtt cctaggtggc
    11161 cgcctcatgg gtgctaaggc tggtatcggt ggtacttatg gtgctatgcc agaactcttc
    11221 ttgaaactca atcagttgat tgcggataag gacctagaaa cagcgcgtga attgcagtat
    11281 gctatcaacg caatcattgg taaactcact tctgctcatg gaaatatgta cggtgtcatc
    11341 aaagaagtct tgaaaatcaa tgaaggcttg aatattggat ctgttcgttc accattgaca
    11401 ccagtaattg aagaagatcg tccagttgta gaagcggctg cagccttgat tcgtgaaacc
    11461 aaggagcgct tcctctaatc taaaaggagg tatttatgac atactacgtt gcaattgata
    11521 tcggtggaac taacatcaag tatggtttgg ttgatcaaga ggggcaactt cttgaatcac
    11581 atgaaatgcc aacagaggcg cataagggtg gacctcatat cttacaaaag accaaagata
    11641 tcgtagctag ttatttagaa aaaggcccag tagcaggtgt tgccatatct tctgctggga
    11701 tggtggatcc ggataagggt gagattttct atgctgggcc gcaaatccct aactacgcag
    11761 gcacccagtt caaaaaggaa atcgaagaaa gctttactat tccttgtgag attgaaaatg
    11821 atgtcaactg tgcaggtctt gctgaggcag tatctggttc aggcaaggga gcaagtgtga
    11881 cactttgctt gaccattgga accggtatcg gtggttgctt gattatggat aggaaagtct
    11941 tccatggttt tagtaattca gcctgtgaag tcgggtatat gcatatgcag gatggagctt
    12001 ttcaggatct cgcttctaca acagctttag tgaaatatgt agctgaagcc catggagaag
    12061 atgttgatca gtggaatggc cgacgtatct ttaaggaagc tactgaagga aacaaaatct
    12121 gcatggaagg tattgaccgt atggttgact atctaggaaa aggtctggca aatatttgct
    12181 acgttgccaa tccagaagtg gtcattcttg gtggtggtat catggggcaa gaggctatcc
    12241 tcaaacctaa gatccgcaca gccttgaaag aggctttggt accaagttta gcagaaaaaa
    12301 cacgattaga atttgcccat caccaaaata cagcagggat gttgggtgca tattatcatt
    12361 ttaagacaaa acaatcctag tttggctcag ccaaactagg attttcttac acgtttttgt
    12421 ctacgatagc cgttgagttt tttattttcc cagtagctat taaagatttt ttccttgctt
    12481 tcgcgattga tttccaaaaa gtaggcataa atcaaatcga taaagaagag cataggaagt
    12541 tgagcggata ttcgttggat ataggagggt tggctgtggg tggctacaag aacagtctct
    12601 gtataggtct ggctatcttt attgggaaca cttgtaaaga gtacagtctt tgcccccatc
    12661 tccttggcat ctaatagact atctaaaata gaaggagttg agcctgaaag tgagaagccc
    12721 agtactagac aattttcatc catgatgctg gttgtccagg caaagccgtc ttggtctgtc
    12781 aaagcttcgc agaccacacc taatcgcata aaacgtaatt tcatttcacg ggcgacgagg
    12841 ccagaactcc ctgttccaaa gaagtagata cgctcagcat cttcgattag ctgggcaatt
    12901 cgttctagtt ggatttcgtc aatcaagtct tgtgtttgtt ccctcatatt gctataactt
    12961 ctgaggactc gtttggtcag tggactgtgc ttggagactt ggttggcttg attttctgcc
    13021 tgatgttggt attggaaaat aaattctcgg tagccagtaa agccacactt tttagcaaag
    13081 cgggtcaaag cagcttgaga aatatgtaat ttttgggtga cttgttgaga agataaatca
    13141 tctgtaatcg tttcagcttg caaaaaatag cgagcgattt cttgctctag gtctgtcatt
    13201 tcttcaaaat gtgaatcaat gatagttgcg atatctggtt tgtccatagg gaaagctcct
    13261 ttacatgagt catactggaa gactagatca gggaatagtc acacttcatt ataacacata
    13321 atataaggat agataaataa aaacgcatct ctgttttaaa aacgaaaaaa tcgaaaaagc
    13381 ttctctcttt tccataattt tctactcaaa ttgtggtaca attaagagta agattttaag
    13441 ttagaaatga gactgatttg tatgagaaaa tttaacagcc attcgattcc gattcggctt
    13501 aatttattgt tttcaatcgt cattttactc tttatgacca ttattggtcg tttgttgtat
    13561 atgcaggttt tgaacaagga tttttacgaa aaaaagctag cctcagctag tcagaccaag
    13621 attacaagca gttcagcccg tggggaaatt tatgatgcta gtggaaaacc tttggtagaa
    13681 aatacgttaa agcaggttgt ttcctttacg cgtagcaata aaatgacggc tacagactta
    13741 aaagaaacag ctaaaaagtt actgacttat gtgagcatca gttctccaaa tttgacagaa
    13801 cgccagctgg cggattacta tttggctgat cctgaaatct ataaaaaaac agtggaagct
    13861 ctcccaagcg agaaacgctt ggattcagat ggcaatcgtc tatccgaatc agaactgtat
    13921 aacaatgcgg tcgatagtgt acaaacgagt caactaaact atacagagga tgaaaagaaa
    13981 gaaatctatc tttttagtca gttaaatgct gttggaaact ttgcgacagg aaccattgcg
    14041 acagatcctc taaatgattc tcaggtggct gttattgcct ctatttcaaa ggagctgcct
    14101 ggcattagta tttctacttc ttgggataga aaggttttgg aaacttccct ttcttctata
    14161 gttgggagtg tatccagtga aaaagctggt ctcccagcgg aagaagcaga agcctatctt
    14221 aaaaaaggct attctctaaa tgatcgtgta ggaacctcct atttggaaaa gcaatatgaa
    14281 gagaccttac aaggaaaacg ctcggtaaaa gaaatccatc tggataaata tggcaatatg
    14341 gaaagcgtgg atacaattga ggaaggtagt aagggaaaca atatcaaact gaccattgat
    14401 ttggccttcc aagatagcgt ggatgcttta ctgaaaagtt atttcaattc cgagctagaa
    14461 aatggtggag ccaagtattc tgaaggtgtc tatgcagtcg cccttaaccc aaaaacaggt
    14521 gcggttttgt ctatgtcagg gattaaacat gacttgaaaa cgggagagtt gacgcctgat
    14581 tccttgggaa cggtaaccaa tgtctttgtt ccaggttcgg ttgtcaaggc ggcgaccatc
    14641 agctcaggtt gggaaaatgg agtcttgtca ggaaaccaga ccttgacaga ccagtccatt
    14701 gtcttccaag gttcagctcc catcaattct tggtatactc aggcttacgg ttcattccct
    14761 atcacagcgg tccaagctct ggagtattca tcaaatacct atatggtcca aacagcctta
    14821 ggtcttatgg ggcaaaccta tcaacccaat atgtttgtcg gcaccagcaa tctagagtct
    14881 gctatggaga aattgcgttc aacctttggc gaatatggct tgggtactgc gacaggaatt
    14941 gacctaccag atgaatctac tggatttgtt cccaaagagt atagctttgc taattacatt
    15001 actaatgcct ttgggcagtt tgataactat acgccgatgc agttggctca gtatgtagca
    15061 actattgcaa ataatggtgt tcgtgtggct cctcgtattg ttgaaggcat ttatggtaat
    15121 aatgataagg gaggactggg tgacttgatt cagcaactgc aaccgacaga gatgaataag
    15181 gtcaatatat ccgactccga tatgagcatc ttgcaccaag gtttttatca ggttgcccat
    15241 ggtactagtg gattgacaac tggacgtgcc ttttcaaatg gtgccttggt atccattagc
    15301 ggaaaaacag gtacagccga aagctatgtg gcagatggtc agcaagcaac caataccaat
    15361 gcggtggcct atgccccatc tgataatccc caaatcgctg tcgcagtggt ctttcctcat
    15421 aataccaatc taacaaatgg tgtaggacct tccattgcgc gtgacattat caatctgtat
    15481 caaaaatacc atccaatgaa ctagaaagga aattatgctt tatccaacac ctattgccaa
    15541 gttgattgac agttattcta agttaccagg tatcgggatt aagacggcta cgcgtctggc
    15601 cttttatacg attgggatgt ctgctgatga tgtcaatgaa tttgcaaaaa atctcctttc
    15661 tgctaagaga gaattgacat attgttctat ttgtggacgt ttgacagacg acgatccttg
    15721 ttctatctgt actgatccga ctcgtgacca gacaacaatt ttagttcttg aggatagtag
    15781 agatgtggca gccatggaaa atatccaaga ataccatgga ctctatcatg tcctgcatgg
    15841 cctcatttct cctatgaatg gtatcagtcc ggacgatatc aatctcaaga gccttatgac
    15901 tcgtcttatg gatagtgagg tttcagaagt gattgtggcg actaatgcta cagcggatgg
    15961 tgaagcgact tccatgtatc tttcacgttt gctcaagccg gctggtatca aggttacgcg
    16021 tctagcacga ggtctcgctg tgggagcgga cattgagtat gcggacgaag tgacactctt
    16081 acgagcgatt gaaaatcgga cagagttgta agtgtaggca aatttacgaa ctcccttcat
    16141 ttataaaaaa tcaaagaggc tgaaaatcgt tcctatcggc ctctttttgt atagtgtgat
    16201 gagtaggatc gggttcaagt tttaaaaaac caagcaaata tgatatacta aagagcgagt
    16261 attctagtag aattaggaca aataatatga aacaaacgat tattctttta tatggtggac
    16321 ggagtgcgga acgcgaagtc tctgtccttt cagctgagag tgtcatgcgt gcggtcaatt
    16381 acgaccgttt cacagtcaag actttcttta tcagtcagtc aggtgacttt atcaaaacac
    16441 aggaatttag tcatgctccg gggcaagaag accgtctcat gaccaatgaa accattgatt
    16501 gggataagaa agttgcacca agtgctatct acgaagaagg tgcagtggtc tttccagtcc
    16561 ttcacgggcc aatgggagaa gatggctctg ttcaaggatt cttggaagtt ttgaaaatgc
    16621 cttacgttgg ttgcaacatt ttgtcatcaa gtcttgccat ggataaaatc acgactaagc
    16681 gtgttctgga atctgctggt attgcccaag ttccttatgt ggctatcgtt gaaggcgatg
    16741 atgtgactgc taaaatcgct gaagtggaag aaaaattggc ttatccagtc ttcactaagc
    16801 cgtcaaacat ggggtctagt gtcggtattt ctaagtctga aaaccaagaa gaactccgtc
    16861 aagccttaaa acttgccttc cgatatgaca gccgtgtctt ggttgagcaa ggagtgaatg
    16921 cccgtgaaat tgaggttggc ctcttgggta actacgatgt caagagcacg ctacctggag
    16981 aagttgtcaa ggacgttgcc ttttatgact acgatgccaa gtatattgat aacaagatta
    17041 ctatggatat tcctgccaaa atcagtgatg atgtggtggc tgtcatgcgt caaaatgcag
    17101 aaacagcctt ccgtgccatt ggtggccttg gtctatctcg ttgcgatttc ttctatacag
    17161 ataagggaga gatttttctc aacgagctca ataccatgcc aggttttacc cagtggtcta
    17221 tgtacccact actttgggac aatatgggga tcagctaccc aggactaatc gagcgtttgg
    17281 ttgaccttgc caaggaaagc tttgacaagc gcgaagcgca tttgatataa aatgaaagag
    17341 agggtagaag ccagaaccat cactgcacgg tgactagagt tctcggactt cagccctttt
    17401 taaaggagta gaaatgaaat taacaatcca tgaaattgcc caagttgttg gagccaaaaa
    17461 tgatatcagt atctttgagg acacccagtt agaaaaagct gagtttgata gtcgtttgat
    17521 tggaactgga gatttatttg tgccacttaa aggtgcgcgt gatggccatg actttattga
    17581 aacagccttt gaaaatggtg cagcagtaac cttgtctgag aaagaggtct caaatcatcc
    17641 ttacatttta gtagatgatg ttttgacagc ctttcaatcc ctagcatcct actatcttga
    17701 aaaaacgact gttgatgtct ttgctgttac aggttcaaat ggcaagacaa cgactaagga
    17761 tatgttggcg catttactgt caacaagata caagacctac aaaacacaag gcaattacaa
    17821 taatgagatt ggccttcctt acacagttct ccacatgcct gaaggaacag aaaagttggt
    17881 cttggagatg ggacaggatc acttgggcga tattcatctc ttgtctgaat tggctcgtcc
    17941 aaaaacagcc atcgtgacct tggttggaga agcccatttg gcctttttca aagaccgttc
    18001 agagattgct aagggaaaaa tgcaaattgc agacggaatg gcttcaggtt ccttgctttt
    18061 agcgccggct gaccctatcg tagaggacta tttgccaact gataaaaagg tggttcgttt
    18121 tgggcaaggg gcagagctgg aaattactga cttggttgag cgcaaagata gtctgacctt
    18181 caaggccaat ttcttagagc aagcccttga tttgccagta actggcaagt acaatgcgac
    18241 aaatgctatg attgcatcct atgttgcctt gcaagaagga gtttcagagg agcaaattcg
    18301 tttggccttc caagatcttg aattgacgcg taaccgtacc gagtggaaga aagcagccaa
    18361 tggagcagat atcctgtcag atgtttacaa tgccaatcca actgctatga aactgatttt
    18421 agagactttc tctgccattc cagccaatga aggtggcaag aaaattgcag tgttggcgga
    18481 tatgaaggag cttggtgacc agtctgttca acttcataat cagatgattt tgagcctttc
    18541 tccagatgtg cttgataccg tgattttcta tggacaagat attgctcagt tggctcaatt
    18601 ggccagtcaa atgttcccaa tcggccacgt ttactacttc aagaaaacag aagaccagga
    18661 tcaatttgaa gacctagtca agcaggtcaa ggaaagcctt ggagcccatg accaaatcct
    18721 gctcaaaggc tctaactcta tgaatctagc caagttggta gaaagtttag aaaatgaaga
    18781 caagtgattt tgtcaagtat ttgcaaagaa tgattgccat tacagatact ggcttaacct
    18841 ttacaaaaga tccgtttgac cgtgagcgct acgaagactt gcgaagtctg ttatctgaaa
    18901 tgttgaatca agcatcagac cttgattccg aagaagtggc agaagtcttg aagccaactt
    18961 ctgcttatgc gactccctta atggacgtcc gtgcttggat tgttgaggat gagaagattt
    19021 gtctggttag gggacaagga gaggatagtt gggctttgcc aggtggcttt ggtgaagtcg
    19081 gctattctcc aacagaaaat attctcaagg aaattgaaga agaaaccggt tttaaagcca
    19141 aagttgaaag actgctagct gtttttgata ccaatcgttt ccaactacag agcaaacagt
    19201 atacaaagtt tgtttttgga tgtaagcttc ttgatggaca attccaagaa aatcaagaaa
    19261 ttgctgacct tcaatttttt gccattgacc aactgccgaa cttatctgaa aaacgcatta
    19321 ccaaggagca aatagagctt ctttggcagg tttatcaagg tcataggggg caatatcttg
    19381 actaagaaga tgattatcgt atttctaaat ccatttttaa caactagcat ggtataataa
    19441 tatgcaggaa aattttgaat tatgaggaag actagatgaa tttatgggat attttcttta
    19501 cgactcaggc aaccgagccg cccaaatttg accttttttg gtatgttagc ctatttacgc
    19561 tcttagcctt aaccttttat acagcccatc gctatcgtga aaagaaggtt taccaacgat
    19621 ttttccaaat cttgcagact gttcagttaa tccttcttta tggttggtac tgggtcaatc
    19681 atatgccact gtcagaaagc ctaccctttt accattgccg tatggctatg tttgtggtac
    19741 tcttgcttcc tggtcaatcc aaatataaac aatactttgc attattggga acatttggga
    19801 cattagcagc ctttgtttat ccagtgccag atgcttaccc ttttccacat atcaccattc
    19861 tatcctttat ctttggtcat ttagcactct tggggaactc tctagtttat ctattgagac
    19921 agtataatgc gcgattgctg gatgtgaagg gaatttttct catgaccttt gccctaaatg
    19981 ccttgatttt tgtggtcaat ttggtgacag gtggcgatta cggatttttg acaaaaccgc
    20041 cattggttgg ggatcacggt ctagtagcta attatttact tgtttcaatt gtgctggtag
    20101 ctactatcag tttgactaag aaaatcttag aattcttttt agctcaagaa gcagaaaaaa
    20161 tgattgcaaa ggaagcttaa cacagagctt tcttttttgc tcttagagag tttttacaag
    20221 cagcttataa aataagaatt tctgaataga caaactcaaa aaatggctgg gaaatttagg
    20281 aaaaaagcaa gcacgattaa attttttgtg ttataatatt ttgtgaatag ctatgcctat
    20341 gtttagctat ggaataatac gaagtgcgaa acttggaaga tagagaggaa gcgatgtaat
    20401 ggctagagaa ggctttttta caggtctaga tattggaaca agctctgtca aggtgcttgt
    20461 ggccgagcag agaaatggtg aattaaatgt aattggcgtg agtaatgcca aaagtaaagg
    20521 tgtaaaggat ggaattattg ttgatattga tgcagcagca actgctatca agtcagccat
    20581 ttcccaagcg gaagaaaagg caggcatttc gattaaatca gtgaatgtcg gcttgcctgg
    20641 taatcttttg caggtagaac caactcaggg gatgattcca gtaacatctg atactaagga
    20701 aattacggat caagatgttg aaaatgttgt caaatcagct ttgacaaaga gtatgacacc
    20761 tgaccgtgaa gtcattacct ttattcctga agaatttatt gtggatggtt tccaagggat
    20821 tcgtgaccca cgtggcatga tgggggttcg ccttgaaatg cgtggtttgc tttatacagg
    20881 acctcgtact atcttgcaca atttgcgtaa gacggttgag cgtgcaggtg ttcaggttga
    20941 aaatgttatc atttcaccac tagcaatggt tcagtctgtt ttgaacgaag gggaacgtga
    21001 atttggtgct acagtgattg atatgggggc aggtcaaacg actgtcgcta caatccgtaa
    21061 tcaagaactc cagttcacac atattctcca agaaggtgga gattatgtaa ctaaagatat
    21121 ctccaaggtt ttgaaaacct ctcgcaaatt agcggaaggc ttgaaactga attacgggga
    21181 agcctatccg cctcttgcaa gcaaagaaac cttccaagta gaggttattg gagaagtaga
    21241 agcagtcgaa gtgacggaag cctacttgtc agaaattatt tctgcacgaa tcaagcacat
    21301 ccttgaacaa atcaagcaag aattagatag aaggcgtcta ttggacctcc ctggtggtat
    21361 tgtcttaatc ggtgggaatg ccattttacc aggtatggtt gagcttgctc aggaagtctt
    21421 tggcgtccgt gtcaagcttt atgttccaaa tcaagttggt atccgtaatc cagcctttgc
    21481 gcatgtgatt agtttatcag aatttgcggg tcaattaaca gaagttaatc ttttggctca
    21541 gggagcgata aaaggtgaga atgacttaag tcatcagcca attagttttg gtgggatgct
    21601 gcaaaaaaca gctcagtttg tacaatcaac gcctgttcaa ccagctcctg ctccagaagt
    21661 agagccggtg gcgcctacag aaccaatggc ggatttccaa caagcttcac aaaataaacc
    21721 gaaattagca gatcgtttcc gtggattgat cggaagcatg tttgacgaat aaagaggaaa
    21781 aataaattat gacattttca tttgatacag ctgctgctca aggggcagtg attaaagtaa
    21841 ttggtgtcgg tggaggtggt ggcaatgcca tcaaccgtat ggtcgacgaa ggtgttacag
    21901 gcgtagaatt tatcgcagca aacacagatg tacaagcatt gagtagtaca aaagctgaga
    21961 ctgttattca gttgggacct aaattgactc gtggtttggg tgcaggaggt caacctgagg
    22021 ttggtcgtaa agccgctgaa gaaagcgaag aaacactgac ggaagctatt agtggtgccg
    22081 atatggtctt catcactgct ggtatgggag gaggctctgg aactggagct gctcctgtta
    22141 ttgctcgtat cgccaaagat ttaggtgcgc ttacagttgg tgttgtaaca cgtccctttg
    22201 gttttgaagg aagtaagcgt ggacaatttg ctgtagaagg aatcaatcaa cttcgtgagc
    22261 atgtagacac tctattgatt atctcaaaca acaatttgct tgaaattgtt gataagaaaa
    22321 caccgctttt ggaggctctt agcgaagcgg ataacgttct tcgtcaaggt gttcaaggga
    22381 ttaccgattt gattaccaat ccaggattga ttaaccttga ctttgccgat gtgaaaacgg
    22441 taatggcaaa caaagggaat gctcttatgg gtattggtat cggtagtgga gaagaacgtg
    22501 tggtagaagc ggcacgtaag gcaatctatt caccacttct tgaaacaact attgacggtg
    22561 ctgaggatgt tatcgtcaac gttactggtg gtcttgactt aaccttgatt gaggcagaag
    22621 aggcttcaca aattgtgaac caggcagcag gtcaaggagt gaacatctgg ctcggtactt
    22681 caattgatga aagtatgcgt gatgaaattc gtgtaacagt tgttgcaacg ggtgttcgtc
    22741 aagaccgcgt agaaaaggtt gtggctccac aagctagatc tgctactaac taccgtgaga
    22801 cagtgaaacc agctcattca catggctttg atcgtcattt tgatatggca gaaacagttg
    22861 aattgccaaa acaaaatcca cgtcgtttgg aaccaactca ggcatctgct tttggtgatt
    22921 gggatcttcg ccgtgaatcg attgttcgta caacagattc agtcgtttct ccagtcgagc
    22981 gctttgaagc cccaatttca caagatgaag atgaattgga tacacctcca tttttcaaaa
    23041 atcgttaagt aaatgaatgt aaaagaaaat acagaacttg tttttcgaga agttgcagag
    23101 gctagtctga gtgctcatcg agagagtggt tcggtctctg tcattgcagt taccaagtat
    23161 gtagatgtac cgacagcgga agccttgctt ccgctaggtg tccatcatat cggtgaaaat
    23221 cgtgtagata agtttctgga aaaatatgaa gctttaaaag atcgagatgt gacttggcat
    23281 ttgattggta ccttgcaaag acgtaaggtg aaagatgtca ttcaatacgt tgattatttc
    23341 catgcattgg actcagtaaa gttagcaggg gaaattcaaa aaagaagtga ccgagtcatc
    23401 aagtgtttcc ttcaagtaaa tatttctaaa gaagaaagca aacacggttt ttcgagagag
    23461 gaactgctgg aaatcttgcc agagttagcc agactagata agattgaata tgttggttta
    23521 atgacgatgg caccttttga ggctagcagt gagcagttga aagagatttt caaggcggcc
    23581 caagatttac aaagagaaat tcaagagaaa caaattccaa atatgcctat gaccgagtta
    23641 agtatgggaa tgagtcgtga ttataaagaa gcgattcaat tcggttccac ttttgttcgt
    23701 ataggtacat cattttttaa gtaggagaga accatgtctt taaaagatag attcgataga
    23761 tttatagatt attttacgga ggatgaggat tcaagtctcc cttatgaaaa aagagatgag
    23821 cctgtgttta cttcagtaaa ttcttcacag gaaccggctc tcccaatgaa tcaaccttca
    23881 cagtcggctg gcacaaaaga gaacaatatc accagacttc atgcaagaca acaggaattg
    23941 gcaaatcaga gtcagcgtgc aacggataag gtcattatag atgttcgtta tcctagaaaa
    24001 tatgaggatg caacagaaat tgttgattta ttggcaggaa acgaaagtat cttgattgat
    24061 tttcagtata tgacagaggt gcaggctcgt cgttgtttgg actatttgga tggagcttgt
    24121 catgttttag ctggaaattt gaaaaaggta gcttctacca tgtatttgtt gacaccagtg
    24181 aacgttattg taaatgttga agatatccgt ttaccagatg aagatcaaca gggtgagttc
    24241 ggttttgata tgaagcgaaa tagagtacga taatgatttt tttaattcgt atgatttata
    24301 atgcagtgga tatttactcc ctaattttgg tagccttcgc tgtcatgtct tggtttccag
    24361 gtgcctacga atccagttta ggtcgttgga ttgtagcgtt ggtaaaacca gtgcttgctc
    24421 ccttgcaacg cctgccttta cagatagcgg gtcttgattt atctgtttgg gttgcgattg
    24481 ttttggttcg atttttagga gaaaacctag tgcgttttct ggcgatgata ggatgaataa
    24541 agggatttat cagcatttct ccatagaaga tcgtccattt cttgacaagg gaatggaatg
    24601 gataaagaag gtagaagata gctatgctcc ttttttaact ccttttatca atcctcatca
    24661 ggagaagcta ttaaagattt tggccaaaac ctatggtctt gcttgtagca gtagtgggga
    24721 attcgtctcg agtgagtatg ttcgagtttt attataccca gattatttcc aaccagagtt
    24781 ttcagatttt gaaatatctc tccaggaaat tgtgtattcc aataaatttg aatatttaac
    24841 gcatgctaag attttaggga cagtcatcaa tcaattaggg attgaacgga aactttttgg
    24901 agatatccta gtagatgaag aacgggcgca gattatgatt aatcagcagt ttcttctcct
    24961 ctttcaagat ggattaaaga aaattggtcg tatacctgtt tcgctggagg aacgtccttt
    25021 caccgagaaa atagataagc tagaacagta tcgagaactg gatttatctg tgtctagttt
    25081 tcgattagat gttcttttat caaatgtttt gaaactatct aggaatcaag caaaccagtt
    25141 gattgaaaag aaacttgtcc aagtaaatta tcatgtggta gacaaatcag attacactgt
    25201 tcaagttgga gacttgatta gtgtgagaaa atttggtcgc ttgagattac ttcaagataa
    25261 gggacaaacg aaaaaagaga agaaaaaaat aaccgtccag ttattattaa gtaagtgagg
    25321 aatagaatgc caattacatc attagaaata aaggacaaga cttttggaac tcgattcaga
    25381 ggttttgatc cagaagaagt cgatgaattt ttagatattg tggttcgtga ttacgaagat
    25441 cttgtgcgtg cgaatcatga taaaaatttg cgtattaaga gtttagaaga gcgtttgtct
    25501 tactttgatg aaataaaaga ttcattgagc cagtctgtat tgattgccca ggatacagct
    25561 gagcgagtga aacaggcggc gcatgaacgt tcaaacaata tcattcatca agcagagcaa
    25621 gatgcgcaac gcttgttgga agaagctaaa tataaggcaa acgagattct tcgtcaagca
    25681 actgataatg ctaagaaagt cgctgttgaa acagaagaat tgaagaacaa gagccgtgtc
    25741 ttccaccaac gtctcaaatc tacaattgag agtcagttgg ctattgttga atcttcagat
    25801 tgggaagata ttctccgtcc aacagctact tatcttcaaa ccagtgatga agcctttaaa
    25861 gaagtggtta gcgaagtact tggagaaccg attccagctc caattgaaga agaaccaatt
    25921 gatatgacac gtcagttctc tcaagcagaa atggaagaat tacaagctcg tattgaggta
    25981 gccgataaag aattgtctga atttgaagct cagattaaac aggaagtgga aactccaact
    26041 cctgtagtga gtcctcaagt tgaagaagag cctctgctca tccagttggc ccaatgtatg
    26101 aagaaccaga agtagctcca gtgcatccga caggtccaac accagctaca gaaactgttg
    26161 attcagcacc gggatttgaa gcaccgcaag aatctgttac aattttataa gaaatattct
    26221 gagaacaata tcttatcctt atattcccag cgagcaggag atggtgtgag tcctgcattc
    26281 cctatcgata agattatcct ctcaaactat caagtctgaa tctagtaaga tttgacgttc
    26341 cccacgttac gggataagag ggagaaagac taaaactttt tccgaataaa ggtggtacca
    26401 cgattttcgt cctttttgga agtcgtggtt tttaatttgt tattatttat aaaggagata
    26461 ccatgaaact caaagacacc cttaatcttg ggaaaactga attcccaatg cgtgcaggcc
    26521 ttcctaccaa agagccagtt tggcaaaagg aatgggaaga tgcaaaactt tatcaacgtc
    26581 gtcaagaatt gaaccaagga aaacctcatt tcaccttgca tgatggccct ccatacgcta
    26641 acggaaatat ccacgttgga catgctatga acaagatttc aaaagatatt attgttcgtt
    26701 ctaagtctat gtcaggattt tacgcaccat ttattcctgg ttgggatact catggtctgc
    26761 caatcgagca agtattgtca aaacaaggtg tcaaacgtaa agaaatggac ttggttgagt
    26821 acttgaaact ttgccgtgag tacgctcttt ctcaagtaga taaacaacgt gaagatttta
    26881 aacgtttggg tgtttctggt gactgggaaa atccatatgt gaccttgact cctgactatg
    26941 aagcagctca aattcgtgta tttggtgaga tggctaataa gggttatatc taccgtggtg
    27001 ccaagccagt ttactggtca tggtcatctg agtcagccct tgctgaagca gagattgaat
    27061 accatgactt ggtttcaact tccctttact atgccaacaa ggtaaaagat ggcaaaggag
    27121 ttctagatac agatacttat atcgttgtct ggacaacgac tccatttacc atcacagctt
    27181 ctcgtggttt gacggttggt gcagatattg attacgtttt ggttcaacct gttggtgaag
    27241 ctcgtaagtt tgtcgttgct gctgaattat tgactagctt gtctgagaaa tttggctggg
    27301 ctgatgttca agttttggaa acttaccgtg gccaagaact caaccacatc gtaacagaac
    27361 acccatggga tacagctgta gaagagttgg taattcttgg tgaccacgtt acgactgact
    27421 ctggtacagg tattgtccat acagcccctg gttttggtga ggacgattac aatgttggta
    27481 ttgctaataa tcttgaagtc gcagtgactg ttgatgaacg tggtatcatg atgaagaatg
    27541 ctggtcctga atttgaaggt caattctatg aaaaggtagt tccaactgtt attgaaaaac
    27601 ttggtaacct ccttcttgcc caagaagaaa tctctcactc atatccattt gactggcgta
    27661 ctaagaaacc aatcatctgg cgtgcagttc cacaatggtt tgcctcagtt tctaaattcc
    27721 gtcaagaaat cttggacgaa attgaaaaag tgaaattcca ctcagaatgg ggtaaagtcc
    27781 gtctttacaa tatgatccgt gaccgtggtg actgggttat ctctcgtcaa cgtgcttggg
    27841 gtgttccact tcctatcttc tacgctgaag atggtacagc tatcatggta gctgaaacta
    27901 ttgaacacgt agctcaactt tttgaagaac atggttcaag catttggtgg gaacgtgatg
    27961 ccaaagacct cttgccagaa ggatttactc atccaggttc accaaacggc gagttcaaaa
    28021 aagaaactga tatcatggac gtttggtttg actcaggttc atcatggaat ggagtggtgg
    28081 taaaccgtcc tgaattgact tacccagccg acctttacct agaaggttct gaccaatacc
    28141 gtggttggtt taactcatca cttatcacat ctgttgccaa ccatggcgta gcaccttaca
    28201 aacaaatctt gtcacaaggt tttgcccttg atggtaaagg tgagaagatg tctaaatctc
    28261 ttggaaatac cattgctcca agcgatgttg aaaaacaatt cggtgctgaa atcttgcgtc
    28321 tctgggtaac aagtgttgac tcaagcaatg acgtgcgtat ctctatggat attttgagcc
    28381 aagtttctga aacttaccgt aagattcgta acactcttcg tttcttgatt gccaatacat
    28441 ctgactttaa cccagctcaa gatacagtcg cttacgatga gcttcgttca gttgataagt
    28501 acatgacgat ttgctttaac cagcttgtca agaccattcg tgatgcctat gcagactttg
    28561 aattcttgac gatctacaag gccttggtga actttatcaa cgttgacttg tcagccttct
    28621 accttgattt tgccaaagat gttgtttaca ttgaaggtgc caaatcactg gaacgccgtc
    28681 aaatgcagac tgtcttctat gacattcttg tcaaaatcac caaactcttg acaccaatcc
    28741 ttcctcatac tgcggaagaa atttggtcat atcttgagtt tgaaacagaa gacttcgtcc
    28801 aattgtcaga attaccagag gctcaaactt ttgctaatca agaagaaatc ttggatacat
    28861 gggcagcctt catggacttc cgtggacaag ctcaaaaagc cttggaagaa gctcgtaatg
    28921 caaaagttat cggtaaatca cttgaagcac acttgacagt ttatccaaat gaagtggtga
    28981 aaactctact cgaagcagta aacagcaatg tagctcaact tttgatcgtg tctgagttga
    29041 ccatcgcaga aggaccagct ccggaagctg cccttagctt cgaagatgta gccttcacag
    29101 ttgaacgtgc tgctggtgaa gtatgtgacc gttgccgtcg tattgaccca acaacagcag
    29161 aacgcagcta ccaggcagtt atctgtgacc actgtgcaag catcgtagaa gaaaactttg
    29221 cggaagcagt cgcagaagga tttgaagaga aataagattg aaaagtctag gcaaaattca
    29281 atttgagaag aaaagacaac taattttata gtctattaaa cgcattgtat cacgtttttg
    29341 aacacctgat atgatgcgtt ttttatttat tttaaaaatt tgcgaggtat gactttttat
    29401 actcaacaag aatcaaagag aaacttagca agctaacagt agtaagataa aataggaatt
    29461 tgatattagg gataagattg gtaa
//
LOCUS       DBEJHE010000024        27946 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC4 isolate 671759
            SAMN38261586-rid24793303.denovo.24, whole genome shotgun sequence.
ACCESSION   DBEJHE010000024 DBEJHE010000000
VERSION     DBEJHE010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261586
            Sequence Read Archive: SRR26833752
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 27946)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27946)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576136.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576136.1
            Genome Coverage       :: 109x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 19:48:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,067
            CDSs (total)                      :: 2,029
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 131
            CDSs (without protein)            :: 131
            Pseudo Genes (ambiguous residues) :: 0 of 131
            Pseudo Genes (frameshifted)       :: 64 of 131
            Pseudo Genes (incomplete)         :: 59 of 131
            Pseudo Genes (internal stop)      :: 46 of 131
            Pseudo Genes (multiple problems)  :: 32 of 131
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27946
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261586-rid24793303.denovo.24"
                     /strain="GPSC4"
                     /isolate="671759"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            443..1621
                     /locus_tag="ACL3EZ_001456"
     CDS             443..1621
                     /locus_tag="ACL3EZ_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ryptide export MFS transporter"
                     /protein_id="HGR0393007.1"
                     /translation="MSNSFVKLLVSQLFANLADIFFRVTIIANIYIISKSVIATSLVP
                     ILIGISSFVASLLVPLVTKRLALNRVLSLSQFGKTILLAILVGMFTVMQSVAPLVTYL
                     FVVAISILDGFAAPVSYAIVPRYATDLGKANSALSMTGEAVQLIGWGLGGLLFATIGL
                     LPTTFIILVLYIISSFLMLFLPNAEVEVLESETNLEILLKGWKLVARNPRLRLFVSAN
                     LLEIFSNTIWVSSIILVFVTELLNKTESYWGYSNTAYSIGIIISGLIAFRLSEKFLAA
                     KWESILFPLVAMAIVTLTILYFPNAQMFLLFSALVGMLSQLKEVPESVFLQETVEENH
                     LVNVYSVLEVISTLAFSVFVLLMSYITESFGISISFWLSTICLMIEAILIYIRRDYFK
                     "
     gene            1935..2066
                     /locus_tag="ACL3EZ_001457"
     CDS             1935..2066
                     /locus_tag="ACL3EZ_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HGR0393008.1"
                     /translation="MKQRKELYLFLGRTALYFLIFLGLLYFFSYLGQGQGSFIYNEF"
     gene            2087..3637
                     /gene="dltA"
                     /locus_tag="ACL3EZ_001458"
     CDS             2087..3637
                     /gene="dltA"
                     /locus_tag="ACL3EZ_001458"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0047473 - D-alanine [D-alanyl carrier
                     protein] ligase activity [Evidence IEA];
                     GO_process: GO:0019350 - teichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HGR0393009.1"
                     /translation="MSNKPIADMIETIEHFAQTQPSYPVYNVLGQEHTYGDLKADSDS
                     LAAVIDQLGLPEKSPVVVFGGQEYEMLATFVALTKSGHAYIPIDSHSALERVSAILEV
                     AEPSLIIAISAFPLEQVFTPMINLAQVQEAFAQGNNYEITHPVKGDDNYYIIFTSGTT
                     GKPKGVQISHDNLLSFTNWMITDKEFATPSRPQMLAQPPYSFDLSVMYWAPTLALGGT
                     LFTLPSVITQDFKQLFAAIFSLPIAIWTSTPSFADMAMLSEYFNSEKMPGITHFYFDG
                     EELTVKTAQKLRERFPNARIINAYGPTEATVALSAVAVTDEMLATLKRLPIGYTKADS
                     PTFIIDEEGNKLPNGEQGEIIVSGPAVSKGYMNNPEKTAEAFFEFEDLPAYHTGDVGT
                     MTDEGLLLYGGRMDFQIKFNGYRIELEDVSQNLNKSRFIESAVAVPRYNKDHKVQNLL
                     AYVILKDGVREQFERDIDITKAIKEDLTDIMMSYMMPSKFLYRDSLPLTPNGKIDIKG
                     LINEVNKR"
     gene            3634..4878
                     /gene="dltB"
                     /locus_tag="ACL3EZ_001459"
     CDS             3634..4878
                     /gene="dltB"
                     /locus_tag="ACL3EZ_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0070395 - lipoteichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HGR0393010.1"
                     /translation="MMEFFQQLPHLEPYGNPQYFVYVIAATLPIFIGLFFKKRFAWYE
                     VLVSLFFIVTMLVGGKTNQLAALGIYLCWEILLLLFYKHYRKSKDGKWVFYLVSFLSL
                     LPIIFVKVQPAINGTQSLLGFLGISYLTFRSVGIVIELRDGVIKDFTLWEFLRFLLFM
                     PTFSSGPIDRFKRFNENYQAIPERDELMDMLDESVRYIMWGFLYKFILAHVLGETLLP
                     PLKNLALQSGGFFNLYALAVMYTFGLELFFDFAGYSMFALAISNLMGIRSPINFNKPF
                     LSRDLKEFWNRWHMSLSFWFRDFVFMRMVMVLTRKKVFKNRNVTSSMAYIVNMLIMGF
                     WHGVTWYYIAYGLFHGLGLVINDAWVRKKKTLNKERKKAGKAALPENRWIQFLGMVVT
                     FHVVMLSFLIFSGFLNNLWFKK"
     gene            4892..5131
                     /gene="dltC"
                     /locus_tag="ACL3EZ_001460"
     CDS             4892..5131
                     /gene="dltC"
                     /locus_tag="ACL3EZ_001460"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005591431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0036370 - D-alanyl carrier activity
                     [Evidence IEA];
                     GO_process: GO:0019350 - teichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HGR0393011.1"
                     /translation="MDIKSEVIEIIDELFMEDVSDMMDEDLFDAGVLDSMGTVELIVE
                     IENRFDIRVPVTEFGRDDWNTANKIIAGIVELQNA"
     gene            5124..6392
                     /gene="dltD"
                     /locus_tag="ACL3EZ_001461"
     CDS             5124..6392
                     /gene="dltD"
                     /locus_tag="ACL3EZ_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0070394 - lipoteichoic acid metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HGR0393012.1"
                     /translation="MLKRLWMIFGPVLIAGLLVFLLIFFYPTEMHHNLGAEKRSAVAT
                     TIDSFKERSQKVRALSDPNVRFVPFFGSSEWLRFDGAHPAVLAEKYNRSYRPYLLGQG
                     GAASLNQYFGMQQMLPQLENKQVVYVISPQWFSKNGYDPAAFQQYFNGDQLTSFLKHQ
                     SGDQASQYAATRLLQQFPNVAMKDLVQKLASKEELSTADNEMIELLARFNERQASFFG
                     QFSVRGYVNYDKHVAKYLKILPDQFSYQAIEDVVKADAEKNTSNNEMGMENYFYNEQI
                     KKDLKKLKDSQKSFTYLKSPEYNDLQLVLTQFSKSKVNPIFIIPPVNKKWMDYAGLRE
                     DMYQQTVQKIRYQLESQGFTNIADFSKDGGEPFFMKDTIHLGWLGWLAFDKAVDPFLS
                     NPTPAPTYHLNERFFSKDWATYDGDVKEFQ"
     gene            6547..6987
                     /gene="adcR"
                     /locus_tag="ACL3EZ_001462"
     CDS             6547..6987
                     /gene="adcR"
                     /locus_tag="ACL3EZ_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent transcriptional regulator AdcR"
                     /protein_id="HGR0393013.1"
                     /translation="MRQLAKDINAFLNEVILQAENQHEILIGHCTSEVALTNTQEHIL
                     MLLSEESLTNSELARRLNVSQAAVTKAIKSLVKEGMLETSKDSKDARVIFYQLTDLAR
                     PIAEEHHHHHEHTLLTYEQVATQFTPNEQKVIQRFLTALVGEIK"
     gene            6987..7691
                     /locus_tag="ACL3EZ_001463"
     CDS             6987..7691
                     /locus_tag="ACL3EZ_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HGR0393014.1"
                     /translation="MRYITVEDLSFYYDKEPVLEHINYCVDSGEFVTLTGENGAAKTT
                     LIKASLGILQPRIGKVAISKTNTQGKKLRIAYLPQQIASFNAGFPSTVYEFVKSGRYP
                     RKGWFRRLNAHDEEHIKASLDSVGMWEHRDKRLGSLSGGQKQRAVIARMFASDPDVFI
                     LDEPTTGMDAGSKNEFYELMHHSAHHHGKAVLMITHDPEEVKDYADRNIHLVRNQDSP
                     WRCFNVHENGQEVGHA"
     gene            7684..8490
                     /locus_tag="ACL3EZ_001464"
     CDS             7684..8490
                     /locus_tag="ACL3EZ_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HGR0393015.1"
                     /translation="MLSLLSYDFIQRAFLAVIAMSLFSPVLGTFLILRRQSLMSDTLS
                     HVSLSGVAFGLVLGISPTVSTIAIVLIAAVFLEYLRTVYKSFMEIGTAILMSTGLAVS
                     LIVMSKGKSSSSMSLDQYLFGSIVTISEEQVISLFVIAAVVLILTFLFLRPMYILTFD
                     EDTAFVDGLPVRTMSILFNMVTGVAIALMIPAAGALLVSTIMVLPASIALRLGKNFKS
                     VMLLASAIGFLGMVAGLYISYYAETPASASITIIFVTVFILISLVRRFIK"
     gene            8500..10005
                     /gene="adcA"
                     /locus_tag="ACL3EZ_001465"
     CDS             8500..10005
                     /gene="adcA"
                     /locus_tag="ACL3EZ_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding
                     lipoprotein AdcA"
                     /protein_id="HGR0393016.1"
                     /translation="MKKISLLLASLCALFLVACSNQKQADGKLNIVTTFYPVYEFTKQ
                     VAGDTANVELLIGAGTEPHEYEPSAKAVAKIQDADTFVYENENMETWVPKLLDTLDKK
                     KVKTIKATGDMLLLPGGEEEEGDHDHGEEGHHHEFDPHVWLSPVRAIKLVEHIRDSLS
                     ADYPDKKETFEKNAAAYIEKLQALDKAYAEGLSQAKQKSFVTQHAAFNYLALDYGLKQ
                     VAISGLSPDAEPSAARLAELTEYVKKNKIAYIYFEENASQALANTLSKEAGVKTDVLN
                     PLESLTEEDTKAGENYISIMEKNLKALKQTTDQEGPAIEPEKAEDTKTVQNGYFEDAA
                     VKDRTLSDYAGNWQSVYPFLEDGTFDQVFDYKAKLTGKMTQAEYKAYYTKGYQTDVTK
                     INITDNTMEFVQGGQSKKYTYKYVGKKILTYKKGNRGVRFLFEATDADAGQFKYVQFS
                     DHNIAPVKAEHFHIFFGGTSQEALFEEMDNWPTYYPDNLSGQEIAQEMLAH"
     gene            complement(11175..11948)
                     /locus_tag="ACL3EZ_001466"
     CDS             complement(11175..11948)
                     /locus_tag="ACL3EZ_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HGR0393017.1"
                     /translation="MIKDERVLELIEIIKKKKRIAVKELAEITFSSTSTLRRDLIFLE
                     NQGLIKRKHGYVTLSSMNTIELSHQIREGESTRQKRLIASLAKDFIRSGMCVYLDSST
                     TVYELCPYLSELDNLIIFTNGLHTAQTLSETVKDSSKIFITSGEVKHQSCSVVNYDKE
                     NSLLDHFNIDLAFCSARGIDDQYVYEASLSQAISKKNIIDKAHETILLIDSSKFYKTG
                     FFKINPLSKYTTFISDTVPDQKLLDAVELFDGEWVSDIQ"
     gene            12124..13527
                     /locus_tag="ACL3EZ_001467"
     CDS             12124..13527
                     /locus_tag="ACL3EZ_001467"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0019200 - carbohydrate kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase family protein"
                     /protein_id="HGR0393018.1"
                     /translation="MEAVLAIDLGATSGRAIVGYLSENKLVMEEINRFSNLPIRVKGH
                     LSWDIDFLLAKILESIRLANTSYKILSIGIDTWGVDFGLIDNEGKLLSQPVHYRDERT
                     KGVLKEISEMTELEKLYSETGNQIMEINTLFQLFKARQESPDSFYKTNKILLMPDLFN
                     YLLTGKFATEKSIASTTQLFDPRSQNWNQNILKLFELDSSLLPEIVSEGNVLGRIKKE
                     YGLGDIPVVNVCSHDTASAIVSVPKTEGSLFISSGTWSLVGVELTSPILTTESFSYGF
                     TNEVGKDGVITFLKNCTGLWIIEELRRSFERRGKAYSFDDIRTMVEKEKENLPLIDTE
                     STEFATESDMHKTLTEYLAYHHETREWTDGQLFKIVYESLAETYRKAIELLEELTHKV
                     YKRIYVIGGGARASYFNQMIADRTGKEVLTGSTEGTAVGNIVVQLIAMGQLKGMEEAH
                     HVIEEFLQLESYYSQKN"
     gene            13642..14280
                     /locus_tag="ACL3EZ_001468"
     CDS             13642..14280
                     /locus_tag="ACL3EZ_001468"
                     /EC_number="4.1.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001286141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fuculose-phosphate aldolase"
                     /protein_id="HGR0393019.1"
                     /translation="MSDVKQELIKYGKKLVETDLTKGTGGNLSVFDREKQLMAITPSG
                     IDFFEIKESDIVVMDINGNVVEGERLPSSEWYMHLIQYQTRDDIDAIIHAHTTYATVL
                     ACLREPLPASHYMIAVAGKDVRVAEYATYGTKELAVNAAKAMEGRRAVLLANHGILAG
                     AQNLLNAFNIVEEVEYCAKIYCLAKNFGEPVVLPDEEMDLMAEKFKTYGQRK"
     gene            14292..14732
                     /locus_tag="ACL3EZ_001469"
     CDS             14292..14732
                     /locus_tag="ACL3EZ_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RbsD/FucU family protein"
                     /protein_id="HGR0393020.1"
                     /translation="MLKHIPKNISPDLLKTLMEMGHGDEIVLADANYPSASCANKLIR
                     CDGVNIPELLDSILYLMPLDSYVDSSIQFMNVVSGDDIPKIWGTYRQMIEGHGTDLKT
                     ITYLRREDFYERSKKAYAIVATGETSLYANIILKKGVVVERENV"
     gene            14725..15156
                     /locus_tag="ACL3EZ_001470"
     CDS             14725..15156
                     /locus_tag="ACL3EZ_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000483177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGR0393021.1"
                     /translation="MFNRGILVASHGNFASGALMTAEMFVGETTNDRVRTLGLMPGEN
                     IVEFEHYFKNQVNELLDSNQEVIVLTDLIGGSPNNVALSRFLNLDSVDIVTGFNIPLL
                     VELISSYDSKINLEEIVQNAQNSLFNVKQQLNVEEEEDLCL"
     gene            15147..15617
                     /locus_tag="ACL3EZ_001471"
     CDS             15147..15617
                     /locus_tag="ACL3EZ_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000020992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGR0393022.1"
                     /translation="MSIEFVRIDDRLVHGQVVTTWLKKYDIEQVIIVNDRISEDKTRQ
                     SILKISAPVGLKIVFFSVKRFVEVLNSVPIKKRTMLIYTNPKDVYDSIEGNLKLEYLN
                     VGQMSKTEENEKVTGGVALGEEDKYYFKKIVDKGTRVEIQMVPNDKVTMLEKFL"
     gene            15642..16415
                     /locus_tag="ACL3EZ_001472"
     CDS             15642..16415
                     /locus_tag="ACL3EZ_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000899624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HGR0393023.1"
                     /translation="MLFTQALLVTLVGIIATIDYNGPLFMIHRPLVTSAMVGLVLGDF
                     TQGVLIGSALELTWLGVTGIGGYTPPDTISGAIIGTAFGILSGQGETAGIAIAVPIAV
                     ATQQLDVLAKTLDVYFVKKADNDAKNGDYSKIGFYHYSSLVLITLFKIVPIFLAIMLG
                     GEYVADLFAKVPPIVMQGLNSAGALLPSIGFGMLLNMMLKKNMWVFLLIGFICSVYGG
                     MSTIGISLVGIAVAYFYDMIGSKPQETTSSSDVEEDLDL"
     gene            16412..17212
                     /locus_tag="ACL3EZ_001473"
     CDS             16412..17212
                     /locus_tag="ACL3EZ_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HGR0393024.1"
                     /translation="MMNNKVTKVELKKVFKRSFMYGSSWNYERMQNLGFLYTILPVLK
                     KLYPDKDSASPAMKRHLEFFNTHQTAAPFILGVTSAMEEQEGNEGAASITGIKVGLMG
                     PLAGLGDSLFWLTLVPICFSIGASYSKDGGALGIFIALILFNIINIPVKYFGLKYGYT
                     KGSSLIQENNTKGTLNRVTSMATALGLVLVGGLIPSMVGINFGLEFKQGELVISVQEM
                     ITKLIPGFIPMALTLLMCKLIRKGKNPVVLIFSVMAIGVILVVLGILK"
     gene            17271..19565
                     /locus_tag="ACL3EZ_001474"
     CDS             17271..19565
                     /locus_tag="ACL3EZ_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HGR0393025.1"
                     /translation="MKLWYKKAASNWNEALPIGNGHLGGMIYGSATKECIQLNDETIW
                     YRGKSDRNNPDSLLHLKKIREYLLDGEIQKAEELIKLTMFATPRDQSHYELLGELYIE
                     HIDIQSCALSLYERELDLDTAISNVVFEPNSCNLQIKREYFTSFNKNILCCRIVSSVQ
                     NTLNLNINLGRNKRFNDEVSKLDSSTILMSASAGGRKGVQFKVVCHSKVTDGEVSVLG
                     ETIVIRNATEVFLYLKSMTDYWGNIDISSLQGEFSSIDYFTEKDEHVKKYQEQFNRVD
                     FKLDYSKDCLSIPTNLLLENTKKYSNYLTNLLFHYGRYLLISSSQPNGLPANLQGIWC
                     DELNPIWGSKYTININTQMNYWMVGPCDLPEVEYPLFDMLERMREPGRLTAKKMYGAR
                     GFTAHHNTDGFGDTAPQSHAMGAAIWVLTIPWLCTHIWEHYLYFQDERILTEHFEMIK
                     EAFLFFEDYLFEVDGYLMTGPSVSPENKYRLKNGIEGNACLSSTIDNQILRYFCDSCI
                     GIAKQLGDNSDFISRVKELKKKLPKTKIGSNGQIQEWLEDYEEVEPGHRHISPLFGLY
                     PYNEIDIHKTPELAEAAKITINRRLSNANFLSSQEREQAINNWLVSGLHASTQTGWSA
                     AWLIHFFARLYQGEPAYNQINGLLNNATLGNLFLDHPPFQIDGNLGLVSGICELLVQS
                     HHNWLSLIPALPSAWSEGEVKGFRVRGGYKVSFAWKNGDITFLKLEGGNKDQKVRVRI
                     YGKNTDVQNIELVFNSEKIIELNF"
     gene            19575..22691
                     /locus_tag="ACL3EZ_001475"
     CDS             19575..22691
                     /locus_tag="ACL3EZ_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001031112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 98 C-terminal
                     domain-containing protein"
                     /protein_id="HGR0393026.1"
                     /translation="MNKEKIKRKLITILFVCIGMLCFGLLAGVKADNRVQMRTTINNE
                     SPLLLSPLYGNDNGNGLWWGNTLKGAWEAIPEDVKPYAAIELHPAKVCKPTSCIPRDT
                     KELREWYVKMLEEAQSLNIPVFLVIMSAGERNTVPPEWLDEQFQKYSVLKGVLNIENY
                     WIYNNQLAPHSAKYLEVCAKYGAHFIWHDHEKWFWETIMNDPTFFEASQKYHKNLVLA
                     TKNTPIRDDAGTDSIVSGFWLSGLCDNWGSSTDTWKWWEKHYTNTFETGRARDMRSYA
                     SEPESMIAMEMMNVYTGGGTVYNFECAAYTFMTNDVPTPAFTKGIIPFFRHAIQNPAP
                     SKEEVVNRTKAVFWNGEGRISSLNGFYQGLYSNDETMPLYNNGRYHILPVIHEKIDKE
                     KISSIFPNAKILTKNSEELSSKVNYLNSLYPKLYEGDGYAQRVGNSWYIYNSNANINK
                     NQQVMLPMYTNNTKSLSLDLTPHTYAVVKENPNNLHILLNNYRTDKTAMWALSGNFDA
                     SKSWKKEELELANWISKNYSINPVDNDFRTTTLTLKGHTGHKPQINISGDKNHYTYTE
                     NWDENTHVYTITVNHNGMVEMSINTEGTGPVSFPTPDKFNDGNLNIAYAKPTTQSSVD
                     YNGDPNRAVDGNRNGNFNSGSVTHTRADNPSWWEVDLKKMDKVGLVKIYNRTDAETQR
                     LSNFDVILYDNNRNEVAKKHVNNLSGESVSLDFKEKGARYIKVKLLTSGVPLSLAEVE
                     VFRESDGKQSEEDIDKITEDKVVSTNKVATQSSTNYEGVAALAVDGNKDGDYGHHSVT
                     HTKADSNAWWQVDLGEEFTVSKVDIYNRTDAEPQRLSNFDVIFLSSSGEEVFRRHFDK
                     VVDGLLSLKVPSVGAKLVKIELKSAAIPLSLAEVEVYGSKRTPKKLSNIALTKETRQS
                     STDYNGFSRLAVDGNKNGDYGHHSVTHTKGDSPSWWEIDLAQTEELEKLIIYNRTDAE
                     IQRLSNFDIIIYDSNNHEVFKQHIDSLESNNLSIDLKGLKGKKVRISLRNAGIPLSLA
                     EVEVYTYK"
     gene            22748..24514
                     /locus_tag="ACL3EZ_001476"
     CDS             22748..24514
                     /locus_tag="ACL3EZ_001476"
                     /EC_number="5.3.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008736 - L-fucose isomerase activity
                     [Evidence IEA];
                     GO_function: GO:0030145 - manganese ion binding [Evidence
                     IEA];
                     GO_process: GO:0005996 - monosaccharide metabolic process
                     [Evidence IEA];
                     GO_process: GO:0019317 - fucose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose isomerase"
                     /protein_id="HGR0393027.1"
                     /translation="MIQHPRIGIRPTIDGRRQGVRESLEVQTMNMAKSVADLISSTLK
                     YPDGEPVECVISPSTIGRVPEAAASHELFKKSNVCATITVTPCWCYGSETMDMSPDIP
                     HAIWGFNGTERPGAVYLAAVLASYAQKGIPAFGIYGRDVQEASDTAIPEDVKEKLLRY
                     ARAALATGLMRDTAYLSMGSVSMGIGGSIVNSDFFQEYLGMRNESVDMTEFTRRMDRG
                     IYDPEEFERAMVWVKEHIKEGVDRNREDLILSKEEKEKQWEFVIKMFMIGRDLMVGNP
                     RLAELGFEEEAVGHHALVAGFQGQRQWTDHFPNGDFMETFLNTQFDWNGIRKPFVFAT
                     ENDSLNGVSMLFNYLLTNTPQIFADVRTYWSPEAVKRVTGHTLEGCAAAGFLHLINSG
                     SCTLDGTGQATRDGKPVMKPFWELEESEVQAMLENTDFPPANREYFRGGGFSTRFLTK
                     GDMPVTMVRLNLLKGVGPVLQIAEGYTLELPEDVHHTLDNRTDPGWPTTWFAPRLTGK
                     GAFKSVYDVMNNWGANHGAITYGHIGADLITLASMLRIPVNMHNVPEEDIFRPKNWSL
                     FGTEDLESADYRACQLLGPLHK"
     gene            24660..25811
                     /locus_tag="ACL3EZ_001477"
     CDS             24660..25811
                     /locus_tag="ACL3EZ_001477"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_function: GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HGR0393028.1"
                     /translation="MATFYVPAVNLIGKGVVNEVGPYIKELGYKKALLVTDKYIEGSD
                     ILPKVLKPLDTEGIEYVIFSDVEPNPTCKNVTDGVAALQEHGCDFIISLGGGSPQDAA
                     SCISIMATNGGKPQDYEGLHKSAKKGLPVVAINTTAGTSAEITINYVITDEERKVKMV
                     MVDKNSLALISVNDPELMLSKPKGLTAATGMDALTHAVEALVTPGAYDVTKKLSIGAI
                     ELIKEYLPRAVENGHDIEAREGMVNAIFLGGMSFNNAGLGYVHSMAHQLGAVYNLPHG
                     VCCAMLLPVIERENAKRVPEAFRNVAKALGLHVEGKSDQECADYAIVEIEKLSETVGI
                     PKKLTELGIEEKDFDFEYLSKNALIDACAPGNPFMPTLEETIAFYKELF"
     gene            25956..26840
                     /locus_tag="ACL3EZ_001478"
     CDS             25956..26840
                     /locus_tag="ACL3EZ_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HGR0393029.1"
                     /translation="MIFLIVCVLLLVIVTLSTVYVVRQQSVAIIERFGKYQKVANSGI
                     HIRLPFGIDSIAARIQLRLLQSDIVVETKTKDNVFVMMNVATQYRVNEQSVTDAYYKL
                     IRPESQIKSYIEDALRSSVPKLTLDELFEKKDEIALEVQHQVAEEMTTYGYIIVKTLI
                     TKVEPDAEVKQSMNEINAAQRKRVAAQELAEADKIKIVTAAEAEAEKDRLHGVGIAQQ
                     RKAIVDGLAESITELKEVNVGMTEEQIMSILLTNQYLDTLNTFASKGNQTIFLPNTPN
                     GVDDIRTQILSALRAEKK"
     gene            27193..27444
                     /locus_tag="ACL3EZ_001479"
     CDS             27193..27444
                     /locus_tag="ACL3EZ_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657761.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HGR0393030.1"
                     /translation="MKEFQFERKQRFSLRKYAIGACSVLLGTSLFFAGMGDQPVQDTE
                     TSSALISSHYLDEHDLSEKLKSELQWFELENKLLNLWEH"
     gene            27432..27722
                     /locus_tag="ACL3EZ_001480"
     CDS             27432..27722
                     /locus_tag="ACL3EZ_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000501069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005576 - extracellular region [Evidence
                     IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ZmpA/ZmpB/ZmpC family metallo-endopeptidase"
                     /protein_id="HGR0393031.1"
                     /translation="MGALGYYEGFVPYVSNQYKNQAEEEGKPLSDKYIFEKILGKTYA
                     AFKKDQINERVEKLGKLKPITINYNGKSEVIDSKEKLQELMNKAVKDEVAQI"
BASE COUNT         8814 a         4572 c         5911 g         8649 t
ORIGIN      
        1 gaacggcacg tacggtggtg tgagaggggc tagagattat cccctactcg attaactccc
       61 ctgaaattta ttttaattat gcaaatttca cgtatttttg atgctgagac gacgatcctg
      121 ggaacttttc agatattttt ttgactatct aaatctatca ttagaaaagc ttagagcgcc
      181 aaaggatttg agcgtttttc tgatttttaa gactttttcc agtctctttt tcgattgaag
      241 atgtaattat tctactaact aactaacttc ttagtactag ccaacaacga taatcataat
      301 tcctcctaaa attaggaata ataaaggcaa tagtttttgt tttttcatgt aaaaaacctc
      361 acttttgttt tctgctattt tatgctaaaa tattaaaaat caaatttaat tccaaagttt
      421 gtaactaaag ggggagcgct acatgtctaa ttcatttgtc aagttgttag tctctcaatt
      481 atttgcaaat ttagcagata ttttctttag agtaacaatc attgctaaca tatacattat
      541 ttcaaaatca gtaattgcca catcactagt tcctatctta ataggaatat cctcttttgt
      601 tgcgagtctt ttagttccgt tggttactaa aaggttagcg ctaaataggg ttttatcttt
      661 atctcaattt ggaaagacta tattattggc gatactggta ggaatgttta ccgtaatgca
      721 atccgtagcg cctttggtga cctatctatt tgttgttgca atttccatac tagatggttt
      781 tgcagcaccc gtttcctatg ctattgtgcc acgctatgcg accgatttgg gtaaggctaa
      841 ttcagcctta tcaatgactg gtgaagctgt tcaattgata ggttggggat taggtggact
      901 cttgtttgca acaattggtc tgttacctac cacgtttatc attttagtct tgtatatcat
      961 ttctagcttt ctgatgttat ttcttcctaa cgctgaagtg gaggtgttag agtcagaaac
     1021 taatcttgaa attttgctca aaggttggaa gttagttgct agaaatccta gattaagact
     1081 ttttgtatca gcaaatttat tggaaatttt ttcaaatacg atttgggttt cttccattat
     1141 acttgttttt gtaacggagt tattaaataa aacggaaagt tactggggat attctaatac
     1201 agcatactct attggtatta taattagtgg cttaattgct tttaggctat ctgaaaagtt
     1261 ccttgctgct aaatgggaaa gtattctttt tcctcttgta gctatggcaa tagtgacact
     1321 gactattcta tattttccaa acgcacagat gtttttatta ttttcagctt tagttggtat
     1381 gttatcgcaa ctaaaagaag ttcctgaaag tgtatttctt caggaaacag tagaggaaaa
     1441 tcatttagtt aatgtctatt ccgttcttga agtgatttct acattagcat tttcagtatt
     1501 tgttttgcta atgagctata ttactgagag ttttggtatt agcatcagtt tttggctatc
     1561 aaccatttgt ctgatgatag aagctatttt aatttatatc agacgagatt attttaaatg
     1621 agagagtggt taaaaagtct ttaaaaatca gaaaagcgca tagtatcagg tgttgaaaaa
     1681 acttgatatt gtgtgtttta ttatgggaat atttacttca ttgtctcctg aaatggagtt
     1741 ttgaagcagg atcactctat ttgaaaatat acatagaaaa actgtataat ccttaaaata
     1801 atctgaaatc tattggaaac atacggtaaa caattgaaaa gatactatat aaagtggtac
     1861 aatggtagaa aaataagcta gtaagaatca ctcttatttt agcgaaaaat tacagaaatg
     1921 aatggttttt cttgatgaaa cagagaaaag aattgtacct ctttcttggt cggacagcct
     1981 tgtattttct tatctttcta gggctgcttt acttctttag ctatcttggt cagggtcaag
     2041 gaagctttat ctataatgaa ttttaacttg aaggagaatc cctattgtgt caaataaacc
     2101 aatagcagat atgattgaaa ccattgagca ttttgctcag acacagccta gctatcctgt
     2161 ctataatgtt ttggggcagg aacacactta tggcgattta aaggctgatt cggatagttt
     2221 ggctgcagtc attgaccaac taggcttgcc tgagaagtct cctgtggttg tttttggtgg
     2281 ccaagaatat gaaatgttgg caacctttgt agcgctgact aagtcaggtc atgcctacat
     2341 tccaattgat agccattcgg ccttggagcg agtttcagct attttagaag tagcagagcc
     2401 aagcttgatt attgccattt cagcctttcc cttggagcag gtttttacac caatgataaa
     2461 tctagctcag gttcaagaag cctttgccca agggaataac tatgaaatca cgcatccagt
     2521 caagggagat gataattact acattatctt tacttctggt acgactggta agcctaaggg
     2581 agtgcagatt tcacatgata atctcctcag ctttacaaac tggatgatta cggataagga
     2641 atttgcgaca ccgagtcgtc cgcaaatgct ggcacagcca ccttattctt ttgacttgtc
     2701 tgtcatgtat tgggcaccga ccttggcact tggtggtacg cttttcactc ttccttcagt
     2761 catcactcag gactttaagc aactctttgc ggctatcttt tcattgccaa tcgctatctg
     2821 gacatcaaca ccatcctttg cagatatggc catgttgtct gaatacttca acagtgagaa
     2881 aatgcctgga atcacgcatt tctactttga tggtgaagaa ttgacggtca aaacagctca
     2941 aaaactgcgc gagcgtttcc caaatgcccg tatcatcaat gcttacggcc caacagaagc
     3001 gacagtagct ctgtcagcag ttgccgtgac agacgagatg ttagcgactc tcaaacgcct
     3061 accaatcggc tataccaagg ctgattctcc aacctttatc attgacgagg aaggaaataa
     3121 actgccaaat ggtgagcagg gagaaatcat tgtttctggg ccagctgttt caaaaggtta
     3181 tatgaacaat cctgaaaaaa cagcagaagc cttctttgag tttgaagatc tgccagccta
     3241 tcacacaggc gatgtgggaa ccatgacaga tgagggcttg cttctctacg gcggacgcat
     3301 ggacttccag attaagttta acggttaccg cattgagtta gaagatgtct ctcaaaacct
     3361 caacaagtct cgctttatcg aatctgctgt cgcagtaccg cgctataaca aggaccacaa
     3421 ggtacaaaat ctattggctt atgtcatctt aaaagacggt gttcgtgagc agtttgagcg
     3481 agatatcgat attaccaagg ccatcaagga agacctgaca gacatcatga tgtcctatat
     3541 gatgccatct aaattccttt accgagacag tttgccacta actccaaatg gaaagattga
     3601 catcaaagga ttgattaacg aggtgaataa gagatgatgg agttttttca acagcttcct
     3661 catttagagc catatggcaa tcctcagtat tttgtttatg tgattgctgc aaccttgccc
     3721 atctttatag gtctcttttt caagaaacgc tttgcctggt atgaagtgtt ggtaagtctc
     3781 ttctttattg tcaccatgtt ggtgggtgga aagaccaatc aactagctgc cttgggtatt
     3841 tacctttgct gggaaatatt gctcctgctt ttctacaagc attatcgaaa aagcaaggat
     3901 ggcaagtggg tcttctactt agttagtttt ctgtccctac ttccgattat ctttgtcaag
     3961 gtgcaaccag ctatcaatgg aacgcagtct ttgcttgggt tcttgggaat ttcttacctg
     4021 acctttcgtt cggttggaat tgtcatcgag ctgagagatg gagtgattaa ggattttacc
     4081 ctctgggaat tcctccgttt ccttctcttc atgccaactt tctcgagtgg tccaatcgat
     4141 cgctttaagc gatttaatga aaattatcag gctattcctg agcgagatga gttgatggat
     4201 atgctggatg aatctgtccg ctatatcatg tggggctttt tgtataagtt tatcctagct
     4261 catgttttag gagagacctt actacctcct ctgaagaatt tagccttgca gtcaggtggc
     4321 ttctttaatc tctatgcctt ggcagttatg tatacttttg gtctggagct cttctttgac
     4381 tttgcaggtt attctatgtt tgctttggcc atctcaaact tgatgggaat ccgtagccct
     4441 atcaacttta acaagccctt tttatcaagg gatttaaagg agttttggaa tcgctggcat
     4501 atgagtctgt ccttctggtt ccgtgacttt gtctttatgc gaatggtgat ggtgttaacc
     4561 agaaagaaag tctttaaaaa tcgtaatgta acctcaagca tggcctacat tgtaaatatg
     4621 ctgattatgg gattttggca tggcgtgacc tggtactata tcgcctatgg actctttcat
     4681 ggactaggct tggtcatcaa tgatgcctgg gttcgcaaga aaaaaacgct caataaggaa
     4741 cggaaaaaag cagggaaggc tgccctacct gagaatcgct ggattcagtt tcttggcatg
     4801 gttgtcactt tccatgttgt catgttgtca ttcttaatct tttctggatt cttgaataat
     4861 ctatggttta aaaaataaaa ggaaataaaa tatggatatc aaatcagaag ttattgaaat
     4921 tattgatgag ttgtttatgg aagatgtttc tgacatgatg gatgaagatc tttttgatgc
     4981 aggtgtcttg gatagtatgg gaacggttga gttgattgtg gagattgaga accgttttga
     5041 cattcgtgtc cctgtaacag agtttggtcg tgacgactgg aatacagcta ataaaatcat
     5101 agctggtatt gtggagctac aaaatgctta aacgcttatg gatgatcttc ggaccggtct
     5161 tgatcgctgg tttgttggtt tttctgctca ttttctttta tcctactgag atgcatcata
     5221 atctaggagc tgaaaagcgt tcagcagtgg ctactactat cgatagtttt aaggagcgaa
     5281 gtcaaaaagt cagagcacta tctgatccaa atgtgcgttt tgttcccttc tttggctcta
     5341 gtgaatggct tcgttttgac ggtgctcatc ctgcggtatt agctgagaaa tacaatcgtt
     5401 cctaccgtcc ttatctttta ggacaggggg gagctgcatc gcttaaccaa tattttggaa
     5461 tgcaacagat gttaccacag ctggagaata aacaagttgt gtatgttatc tcacctcagt
     5521 ggttcagtaa aaatggctat gatccagcag ccttccagca gtattttaat ggagaccagt
     5581 tgactagttt tctgaaacat caatctgggg atcaggctag tcaatatgca gcgactcgct
     5641 tactgcaaca gttcccaaac gtagctatga aggacctggt tcagaagttg gcaagtaaag
     5701 aagaattgtc gacagcagac aatgaaatga ttgaattatt ggctcgtttt aatgaacgcc
     5761 aggcctcctt ttttggtcag ttttcggtta gaggctatgt taactacgat aagcatgtag
     5821 ctaagtattt aaaaatcttg ccagaccagt tttcttatca agcaatagaa gatgttgtca
     5881 aagcagatgc tgaaaaaaat acttccaata atgagatggg aatggaaaat tatttctata
     5941 atgagcagat caagaaggat ttgaagaaat taaaggattc tcagaaaagc tttacctatc
     6001 tcaagtcgcc agagtataat gacttgcagt tggttttaac acagttttct aaatctaagg
     6061 taaacccgat ttttatcatt ccacctgtta ataaaaaatg gatggactat gctggtctac
     6121 gagaggatat gtaccaacaa acggtgcaga agattcgcta ccagttagaa agtcaaggtt
     6181 ttaccaatat agcagatttt tctaaggacg gcggggagcc tttctttatg aaagacacca
     6241 ttcaccttgg ttggttgggt tggttggctt ttgacaaggc agttgatcct ttcctatcca
     6301 atcccacacc agctccgact taccatctga atgagcgctt tttcagcaaa gattgggcga
     6361 cttatgatgg agatgtcaaa gaatttcaat agataatata atatagaaga gttcaagaat
     6421 gaaactagtt ttcacgtttt ttcttgactc tttttttgct tgtgatataa ttaactggta
     6481 aacaaaatgt caaagaatag tatttttctc ttaaaaaaga gaagtctaaa aggaaaggag
     6541 tcagatatga gacagctagc aaaggatatc aatgcttttt tgaatgaggt gattttgcag
     6601 gcggaaaatc agcatgaaat cctaataggt cattgcacta gcgaggtggc cctgaccaat
     6661 actcaggagc atatccttat gctcttgtca gaggaatctt taacaaattc agaattggcc
     6721 cgtcgtctca atgtcagtca ggcggcagtt accaaggcca ttaagtcttt ggtcaaggaa
     6781 gggatgttgg aaacatctaa agattctaaa gatgcgcgtg tgatttttta tcagttgact
     6841 gacttggctc gtccaatcgc tgaggagcac caccatcacc atgagcatac acttttaacc
     6901 tatgaacaag tggcgactca gtttactcca aatgaacaaa aagtgattca gcggtttttg
     6961 actgctttag taggagaaat caaataatga gatatattac ggtagaggat ttgtccttct
     7021 attatgataa ggagcctgtt cttgaacata tcaattattg tgttgatagt ggggaatttg
     7081 ttaccttgac tggggaaaat ggagcggcta agacgacgct catcaaggct agtcttggaa
     7141 ttctgcaacc acgcattgga aaggtggcta tttcaaagac aaatacgcaa ggtaagaaat
     7201 tgagaatagc ctatcttcct caacaaattg ccagttttaa tgctggtttt ccaagtacgg
     7261 tctatgaatt tgtcaagtcg ggtcgctatc cgagaaaagg ctggttccgt cgtttgaatg
     7321 ctcatgatga ggagcatatc aaggctagtc tggactcagt tggcatgtgg gaacatcgag
     7381 acaaacgctt ggggtctcta tctgggggac aaaagcagcg agcggtaatt gcgcgtatgt
     7441 ttgcttctga ccctgatgtg tttatcctag acgagccgac aacggggatg gatgcaggaa
     7501 gtaaaaatga attttacgaa ctcatgcacc acagcgccca tcatcatggt aaggctgttt
     7561 tgatgattac ccatgaccct gaagaagtta aggattatgc ggatcgcaat attcatctag
     7621 tccgtaacca agactcgcca tggcgttgtt tcaatgttca tgagaatggc caggaggtgg
     7681 gccatgctta gtttattatc ttacgacttt atacagcgcg cctttttggc ggttattgct
     7741 atgagtcttt tctcaccggt attgggaacc ttcctcatct tgcgtcgtca gagtttgatg
     7801 agtgataccc ttagccacgt ctcactttca ggtgtagcct ttggtctggt tttggggatt
     7861 tctccaactg tttctactat tgccattgtc ttgattgcgg cggtctttct ggagtatctc
     7921 cgtacggttt acaagagctt tatggaaatc gggacagcta tcctcatgtc aacaggtctg
     7981 gctgtttctc tgattgtcat gagcaagggt aaaagctcga gttcaatgag tttggaccaa
     8041 tatctctttg gttcgatcgt gactatcagt gaagaacagg tcatttccct ctttgtcatt
     8101 gcggcggttg ttttgatttt gacctttctc tttcttcgtc ctatgtatat cttaactttt
     8161 gacgaagata cggcctttgt ggatggcttg ccagttcgta ccatgtccat tctttttaac
     8221 atggtgacag gggtggctat tgcccttatg attcctgcag caggagctct tctggtatcg
     8281 accattatgg tcttgccagc tagtattgcc ctgcgtctgg ggaaaaactt taaatcggtt
     8341 atgctgcttg ccagtgcgat tggctttttg ggaatggtag caggacttta catttcctac
     8401 tatgcagaaa cacctgcaag tgcaagtatt actattattt ttgtaactgt ctttatacta
     8461 atcagtttag taagacgttt tatcaaatag gagacgaacg tgaaaaaaat tagcttatta
     8521 ctagccagtc tatgtgcctt gtttttagtg gcttgttcca atcaaaaaca ggcagatggt
     8581 aaactcaata tcgtgacaac cttttaccct gtctatgaat ttaccaagca agtcgcagga
     8641 gatacggcta atgtagaact cctaatcggt gctgggacag aacctcatga atacgaacca
     8701 tctgccaagg cagttgccaa aatccaagat gcagatacct tcgtttatga aaatgaaaac
     8761 atggaaacat gggtacctaa attactagat accttggata agaaaaaagt gaaaaccatc
     8821 aaggcgacag gcgatatgtt gctcttgcca ggtggcgagg aagaagaggg agaccatgac
     8881 catggagaag aaggtcatca ccatgagttt gacccccatg tttggttatc accagttcgt
     8941 gccattaaac tagtagagca catccgcgac agcttgtcag cagattatcc tgataaaaaa
     9001 gagacctttg agaagaatgc agctgcctat atcgaaaaat tgcaagcctt ggataaggct
     9061 tacgcagaag gcttgtctca agcaaaacaa aagagctttg tgactcaaca cgcagccttt
     9121 aactatcttg ccttggacta tggactcaaa caagtcgcaa tctcaggact ttctccagat
     9181 gcagagccat cagctgctcg cttggcagaa ttgacagagt atgtcaagaa aaataaaatc
     9241 gcctatatct attttgaaga aaatgcctca caagcccttg ctaacacact ttcaaaagaa
     9301 gcaggtgtca aaactgatgt cctcaatcct ttagaaagtc tgacagaaga ggacaccaag
     9361 gctggagaaa attacatctc tatcatggag aaaaacctca aggctttgaa acaaacaaca
     9421 gaccaagaag gcccagcgat cgagcctgaa aaggcagagg ataccaagac agtccaaaat
     9481 ggttacttcg aggatgcagc tgtcaaggac cgcaccttga gtgactatgc aggtaactgg
     9541 caatcagttt atcctttcct tgaagacggc acgtttgacc aagtctttga ctacaaggct
     9601 aagttgactg gtaagatgac ccaggctgag tacaaggctt actatacaaa aggctatcag
     9661 acagatgtga ctaagattaa cattactgat aatactatgg aatttgttca aggtggacaa
     9721 agcaagaaat atacttacaa gtatgtcggt aagaaaattt tgacttacaa gaaaggcaat
     9781 cgtggcgtgc gtttcctctt tgaagccaca gatgctgacg ctggacaatt caagtatgtt
     9841 cagtttagtg accacaatat cgccccagtt aaggcagaac atttccatat cttttttgga
     9901 ggcacaagcc aagaagccct ctttgaagaa atggacaact ggccaaccta ctacccagat
     9961 aacctatctg gccaagaaat cgcccaagaa atgttagcgc attgatgaga aatcgactag
    10021 ttcataagag ctagtcggtt ttttgatact agatggctaa cttcattata gacctttcag
    10081 aactaaggga acctgaaaaa ataaataaaa ctcttgaaat atctgggctt atatgctaga
    10141 atgtagttag tgtataaggt tcattagaac accaaagccc ctaactagtg ccatagttaa
    10201 gggctttttt gacgtatctt agcgatttaa cgggtgttta taggctagtc agtcggtcta
    10261 cttcttacca tctagccatt tgcagacgaa atacaagata attccagcta taacatctgc
    10321 tataatagta agagcaagct ctggtataag gctcattagt ttcacctcct ctcacgaacc
    10381 cataggaacg taatcggtaa ccgatgacaa aaatagtata ccacactaaa tttagatcat
    10441 caacctcact taatgcttga actattgtag attatatgct aaaatgtagt taattgataa
    10501 ggttcattag aacaccaaag cccctaacta tggccgtagt taagggcttt tttgacgtat
    10561 cttagagatt taacgggtgt ttataggcta gtcagtcggt ctactcctta ctatctagcc
    10621 atctgcagac gaaatacaag ataattccag ctataacatc cgctataata gtaagagcga
    10681 gctctatgat aaggctcatt agtttcacct cctctcacga acccatagga acgtaatcgg
    10741 taaccgatga caaaaatagt ataccacaat acatttagat catcaaggtc acttaattct
    10801 tgaaatatag ggtctaggcg acaaagtctt taaaatcaga aaaacgcata atatcaggtg
    10861 tgcaaaaact tgatactatg cgttttattg tgggaaggtt tactccattt tctcctgaaa
    10921 ttgagttttt gtccagcctc tgtttttggg gttgctaaga aaataatgtc atgtggtgaa
    10981 tatttgtaaa tcagtcagca gacagaacga tactcttcga aaatctcttc acatcatgtc
    11041 agcttcgtct ttccgtatat atgtgactga cttcatcagt tctatctaca acctcaaaac
    11101 agtgtttcga gctgacttga tcaattttca aatctgtact gtgagcaagc tgagactagc
    11161 ttcctatttg attttcattg aatatcagaa acccattctc catcaaataa ttcgactgcg
    11221 tctaataatt tttgatctgg cacggtgtct gaaataaagg ttgtgtattt ggagagggga
    11281 ttaattttaa aaaatccagt cttgtaaaat ttagaactat caatcagtaa gatggtttca
    11341 tgggctttgt caataatatt cttttttgaa atagcttggc tgagagaagc ttcataaaca
    11401 tattggtcat caatacctct tgctgaacaa aatgctaaat cgatattaaa atgatctaat
    11461 aaagaatttt ccttatcgta attgaccacg gaacaggatt gatgtttgac ctcgccagat
    11521 gtgataaaga ttttggagct atctttaaca gtttcagata gggtttgtgc agtatgtaaa
    11581 ccatttgtaa aaataatcaa attatcaagt tcagaaagat agggacaaag ttcgtagaca
    11641 gtcgtactgg aatccagata aacacacata cctgaccgaa taaagtcttt agcgagacta
    11701 gcgattagtc ttttttgcct agtactttct ccttcccgta tttgatgaga aagttcaatt
    11761 gtgttcatag aggacagggt cacgtatccg tgctttcttt tgataagacc ttgattttct
    11821 aagaaaatta aatcacgacg taaggtactt gtgctggaga aagtgatttc tgccagctct
    11881 tttacggcaa ttcttttttt ctttttaata atttcaatca attcaagtac acgttcatct
    11941 tttatcataa gctcctccta atttatcatt tcaactatat tatagcacaa attggaggaa
    12001 tttgaattat ttttatgaat attgggttaa catttgaaca ttatccaagt aagcgttcac
    12061 atattgaaaa aataaaatgt ggggattata ataaacttaa tcaaggacga agagagaaga
    12121 aaaatggaag cggttttagc aatagattta ggtgcgactt ctggaagagc aatcgttggt
    12181 tacctttctg aaaataaact agtaatggaa gaaataaatc gcttttctaa tctacctatt
    12241 agagtaaaag ggcatttatc ttgggatatt gactttctac tagctaaaat tcttgaaagt
    12301 atccgcttgg ctaatactag ttacaagatt ttatctatcg gtattgacac atggggagtt
    12361 gattttggac tgattgataa tgaaggtaag ctgttatcac aacctgttca ttatcgtgat
    12421 gaaagaacaa agggagtgtt aaaggaaata tctgaaatga ctgaattaga aaaactgtat
    12481 tcagagacag gaaatcagat tatggagata aataccttgt ttcaactctt taaggcacgt
    12541 caagaatctc ctgactcttt ctataagacc aataagattc ttttaatgcc agatttgttt
    12601 aattatctct tgacaggtaa gtttgctaca gaaaaaagca ttgcttcaac aactcaatta
    12661 tttgatccta ggagtcaaaa ttggaatcag aatatcttaa aactatttga attggattca
    12721 tctttacttc ctgaaattgt ttcagaggga aatgttcttg gaaggataaa aaaggagtat
    12781 ggtttaggcg atattcctgt tgtgaatgtt tgtagtcatg atacagcaag tgcgattgtc
    12841 tcagtaccta agacagaagg tagtttattt atttcatcag gtacttggtc tttggttgga
    12901 gtggaactta cttcaccgat tcttactacc gaatccttca gttatggatt tacaaatgaa
    12961 gtcggtaaag atggagtgat tacatttctg aagaattgta cagggttgtg gatcatagag
    13021 gaactaagac gttcatttga acgaagaggg aaagcctatt cttttgatga tattaggaca
    13081 atggtggaga aagaaaaaga aaatcttcct ctgattgata ctgaatcaac tgaatttgca
    13141 acagaatctg atatgcacaa gactttgaca gaatatctag cttatcatca tgaaactaga
    13201 gagtggacag atggacaact atttaagatt gtttatgaaa gcctagctga aacgtatagg
    13261 aaagcgatag agttactaga agaactaact cataaggttt ataagaggat atatgtgatt
    13321 ggaggaggtg ctagagccag ttactttaac caaatgattg ctgatagaac tggtaaagag
    13381 gttcttacag gttcgactga gggtacagct gtggggaata ttgttgtgca gctcatagct
    13441 atgggacaat taaaagggat ggaagaagct caccatgtta ttgaggagtt tctacaatta
    13501 gagagttatt actcccaaaa gaattaaaaa gattgagagt ttgtaaattt gcctccctcc
    13561 cccttcttaa gttttgtaca agaagggggg ataattggtg aattgaaaaa tatttagtgt
    13621 tttgatatga ggaggacaag aatgtcagat gtaaaacaag aattaattaa gtatggcaag
    13681 aagctagtag aaacagattt gacgaaagga acaggtggga atctcagcgt tttcgatcgt
    13741 gaaaaacaat tgatggcaat taccccgtcg ggtattgatt tctttgaaat caaagaatcc
    13801 gatattgtag tgatggatat taatggaaat gttgtagagg gagaacgctt gccatctagc
    13861 gaatggtata tgcatttgat tcaatatcaa actcgtgatg atatcgatgc aattatccat
    13921 gctcatacaa cttatgcaac agtattagct tgtctcagag aaccacttcc ggctagtcat
    13981 tatatgattg cagtggcagg gaaagatgtt cgggtagctg agtatgcaac atatggtacg
    14041 aaagaattgg ctgtgaatgc agctaaagca atggaaggtc gtagagcagt tttactagcg
    14101 aatcatggaa ttttagcagg tgcacaaaat ttattgaatg catttaatat tgttgaagaa
    14161 gttgaatatt gtgcaaaaat ttattgttta gctaagaatt ttggagagcc agtagttctt
    14221 cctgatgagg agatggattt aatggcagaa aaatttaaaa catacggtca gagaaaatag
    14281 ggaggatatt aatgttaaaa catataccga aaaatatttc tccagattta ttgaagactt
    14341 taatggaaat gggacatgga gatgaaatag tattagctga cgcgaattat ccttctgcct
    14401 catgtgcaaa taagctaatt cgttgtgatg gcgtaaatat tccagaatta ttagattcca
    14461 ttctgtattt aatgccatta gatagttacg tcgatagttc aattcagttt atgaacgttg
    14521 tttcgggtga tgatattcct aagatatggg gtacctatag acagatgatt gaaggtcatg
    14581 gtacagatct taaaacgatt acttatctta gaagagaaga cttttatgaa cgtagtaaga
    14641 aagcttatgc tattgttgct acaggagaaa cttcacttta tgctaatatt atccttaaga
    14701 aaggagtagt tgttgaaaga gaaaatgttt aatagaggaa ttttagttgc cagtcatggt
    14761 aattttgcta gcggagctct catgaccgca gaaatgtttg ttggtgagac aacaaatgat
    14821 agagttagga cattaggttt gatgcctgga gagaatattg tagagtttga acattatttt
    14881 aaaaatcaag taaatgaact gttagactca aatcaagagg ttatcgtttt gactgacttg
    14941 attggaggaa gtcctaataa tgtggctttg tcacggtttt taaatttgga ttcagttgat
    15001 attgtaacag ggtttaatat ccctctccta gtggaattaa tatcaagtta tgattcaaaa
    15061 atcaatttag aagaaattgt tcaaaatgct caaaatagtt tgtttaatgt taaacaacaa
    15121 cttaacgtag aggaggaaga ggatttatgt ctatagagtt tgttcgtatt gatgaccgtc
    15181 tggtacatgg tcaagttgtc actacgtggc taaaaaagta tgatattgag caagttatca
    15241 ttgttaatga tcgcatctca gaagataaaa cacgacaatc tattttaaag atttctgcac
    15301 cggtaggttt aaaaattgtt ttctttagtg taaaacggtt tgtggaagtt ttaaactctg
    15361 tgccaataaa aaagagaaca atgctgatat atacaaatcc aaaagatgtg tatgattcta
    15421 ttgaaggaaa tttaaaattg gagtacctca atgtaggaca gatgagtaaa acggaggaaa
    15481 atgaaaaggt aacgggaggt gtagctctag gtgaagaaga caaatattat tttaagaaaa
    15541 tagttgataa gggaacgaga gttgaaattc aaatggttcc taatgataaa gttacaatgt
    15601 tggaaaaatt tttataaaaa taatttaagg aggtacagta tatgctattc acacaagcat
    15661 tactggtgac attagttggg attattgcca ctattgacta taatggaccg ttatttatga
    15721 ttcaccgtcc gttagttaca agtgcaatgg ttggcttagt cttaggagat ttcacccaag
    15781 gtgttcttat tggttcagct cttgaattaa cttggctcgg tgtaacaggt attggaggtt
    15841 acactccacc agatactatt tcaggtgcga ttattggtac tgcatttggt attttatctg
    15901 gtcaaggaga aactgctggt atcgctatag cagttccaat tgcagttgct acccaacagt
    15961 tggatgttct tgcaaaaact ttagatgttt attttgtgaa aaaagctgat aatgatgcta
    16021 aaaacggaga ttattcaaag atcggttttt atcattattc aagtttggtt ttaatcacgt
    16081 tatttaaaat tgtaccaatt ttcctagcta ttatgcttgg aggggaatat gtggcagact
    16141 tgtttgctaa ggttccacca atcgttatgc agggacttaa ctctgcaggt gctttactac
    16201 cttcaattgg ttttggtatg cttttaaata tgatgctcaa gaaaaatatg tgggtattct
    16261 tgttgattgg attcatttgt tctgtgtatg gaggaatgtc aaccattggg atctcactag
    16321 ttggtattgc ggtagcatac ttctacgata tgattggaag taaaccacaa gaaacaactt
    16381 caagtagtga tgttgaggag gatcttgatc tatgatgaat aataaagtaa ctaaagttga
    16441 acttaaaaaa gttttcaaac gaagttttat gtatggttct tcatggaact atgagagaat
    16501 gcagaaccta ggttttctat atacaattct tccagtattg aaaaaactat acccagacaa
    16561 agattcagct tctcctgcaa tgaaacgtca ccttgagttt ttcaatactc atcaaacagc
    16621 ggcaccattt attcttggag ttacttccgc tatggaagaa caagaaggaa atgaaggtgc
    16681 agcttcaatt actggtatta aagttggctt gatggggcca ctggctggtc taggagatag
    16741 tttgttctgg ctgacactag ttcctatctg ttttagtatt ggtgcgtctt attctaaaga
    16801 cggcggtgct ttaggtatct ttatcgcctt aatattgttt aatattatta atattcctgt
    16861 taaatatttc ggtttgaaat atgggtatac taagggttct agtcttatcc aagaaaataa
    16921 tacaaaagga acattgaatc gcgttacgag tatggcgaca gcattagggc tagtactagt
    16981 gggtggtttg attccatcaa tggttggtat taattttgga ttagaattta agcaggggga
    17041 acttgttatt tctgttcaag aaatgattac aaaattaatt ccaggattta tccctatggc
    17101 tttgacttta ttaatgtgta aattaattag aaaaggaaag aatccggttg tactaatctt
    17161 tagtgttatg gctattggag ttatcctagt tgttttagga attttgaagt agtagaaagt
    17221 gtggaggtgg tatttgggat atcacctcca ttttggaaga gaggtaaaga gtgaaattat
    17281 ggtataagaa agctgcctca aattggaatg aagccttgcc gattgggaac ggtcatttag
    17341 gtggtatgat ttatggttca gctacaaaag aatgtattca actaaacgat gagactattt
    17401 ggtatagagg aaagtcagat agaaataatc cagactcact attgcatctt aaaaaaattc
    17461 gggaatatct tttagatgga gaaattcaga aagccgaaga attgataaag ttaacaatgt
    17521 ttgctacccc aagagatcaa agccactatg aattacttgg ggaactttac attgagcata
    17581 tagatattca gtcttgtgct ctttcattgt atgaaagaga gctagattta gatacagcta
    17641 tttctaatgt tgtgtttgag cctaatagtt gtaatttaca aataaaaaga gaatatttta
    17701 cgagttttaa taagaatatt ttatgttgcc gtatagtgtc atcagttcaa aacacattaa
    17761 atttaaacat taatttgggt agaaataaac ggtttaatga tgaagtatct aaactggatt
    17821 caagtacaat tttaatgtcg gcctctgctg gaggtagaaa aggtgttcag tttaaagtag
    17881 tatgtcattc taaggttacg gatggtgaag taagtgtatt gggagagaca atagttattc
    17941 ggaatgctac agaggtattt ctttatctca aatcaatgac ggattattgg ggaaatatag
    18001 atatttcttc tcttcaggga gaatttagta gtattgatta ctttacagaa aaagatgaac
    18061 atgtaaaaaa atatcaggag caatttaata gagttgattt taaactagac tatagtaaag
    18121 attgtcttag cattccaacg aatctacttc ttgaaaacac taaaaagtat agtaactact
    18181 tgactaactt gttatttcat tatggaagat atctgttaat atcgtctagt caaccgaatg
    18241 gtttacctgc caatcttcaa ggaatatggt gtgatgaatt aaatccaatt tggggttcta
    18301 aatatacgat taatattaat actcaaatga attattggat ggtaggtcca tgtgatttac
    18361 cagaagtaga atatccatta tttgatatgc tcgaaagaat gagagaaccg ggaagactaa
    18421 ccgctaagaa aatgtatgga gctagaggtt ttacagcaca tcataatacg gatggttttg
    18481 gcgatacggc tccccaatct catgccatgg gggctgcaat ttgggtatta actattccat
    18541 ggttatgtac tcatatttgg gaacactatt tatatttcca agatgagcgt attcttacgg
    18601 aacattttga aatgataaaa gaagcatttc ttttctttga agattattta tttgaggtgg
    18661 atggctactt gatgacaggt ccaagtgtct caccggaaaa taaatatcgc ttaaaaaatg
    18721 gtattgaagg aaatgcttgt ctatcatcta caattgataa tcaaattcta agatattttt
    18781 gtgattcatg cattggcatt gcaaaacaat taggagacaa ttcggatttt attagtcgtg
    18841 tgaaggagtt aaaaaagaaa ctacctaaaa caaaaatagg tagtaatggg caaatccaag
    18901 aatggttaga agattatgaa gaagtagagc ctgggcatag acacatttca cctctatttg
    18961 ggctttatcc ttataatgag attgatattc ataaaactcc ggaattagca gaagcagcta
    19021 aaatcactat caataggaga ttatcaaacg ctaatttttt atcttcacag gagagggagc
    19081 aagcgattaa taattggtta gtaagtggtt tgcatgctag tacacaaaca ggttggagtg
    19141 ctgcatggct gattcatttt tttgcgagac tatatcaagg tgaacctgct tataaccaga
    19201 ttaatggttt gttaaataat gcgactcttg gcaatttatt tcttgaccat ccaccatttc
    19261 aaattgatgg taatttaggt ttggtgagtg gaatttgtga attattagta cagagccatc
    19321 ataattggtt atcactaatt ccagctttac cttctgcttg gtcagaagga gaagtgaaag
    19381 gtttcagagt aagaggagga tataaggtat cgtttgcttg gaaaaatggg gatataacat
    19441 tcctaaaatt ggaaggagga aacaaagatc aaaaagtaag agtaagaata tatggcaaaa
    19501 atactgatgt acaaaatatt gaattggtat ttaattcaga aaaaattatt gagttaaatt
    19561 tttaggtata agtcatgaat aaagaaaaaa taaaaagaaa attaatcaca atactgtttg
    19621 tatgtattgg gatgttatgt tttggattgt tagcaggagt taaggctgat aatcgtgttc
    19681 aaatgagaac gacgattaat aatgaatcgc cattgttgct ttctccgttg tatggcaatg
    19741 ataatggtaa cggattatgg tgggggaaca cattgaaggg agcatgggaa gctattcctg
    19801 aagatgtaaa accatatgca gcgattgaac ttcatcctgc aaaagtttgt aaaccaacaa
    19861 gttgtattcc acgagatacg aaagaattga gagaatggta tgtcaagatg ttggaggaag
    19921 ctcaaagtct aaacattcca gttttcttgg ttattatgtc ggctggggag cgtaatacag
    19981 ttcctccaga gtggttagat gaacaattcc aaaagtatag tgtgttaaaa ggtgttttaa
    20041 atattgagaa ttattggatt tacaataacc agttagctcc gcatagtgct aaatatttgg
    20101 aagtttgtgc caaatatgga gcgcatttta tctggcatga tcatgaaaaa tggttctggg
    20161 aaactattat gaatgatccg acattctttg aagcgagtca aaaatatcat aaaaatttgg
    20221 tgttggcaac taaaaatacg ccaataagag atgatgcggg tacagattct atcgttagtg
    20281 gattttggtt gagtggctta tgtgataact ggggctcatc aacagataca tggaaatggt
    20341 gggaaaaaca ttatacaaac acatttgaaa ctggaagagc tagggatatg agatcctatg
    20401 catcggaacc agaatcaatg attgctatgg aaatgatgaa tgtatatact gggggaggca
    20461 cagtttataa tttcgaatgt gccgcgtata catttatgac aaatgatgta ccaactccag
    20521 catttactaa aggtattatt cctttcttta gacatgctat acaaaatcca gctccaagta
    20581 aggaagaagt tgtaaataga acaaaagctg tattttggaa tggagaaggt aggattagtt
    20641 cattaaacgg attttatcaa ggactttatt cgaatgatga aacaatgcct ttatataata
    20701 atgggagata tcatattctt cctgtaatac atgagaaaat tgataaggaa aagatttcat
    20761 ctatattccc taatgcaaaa attttgacta aaaatagtga ggaattgtct agtaaagtca
    20821 actatttaaa ctcgctttat ccaaaacttt atgaaggaga tgggtatgct cagcgtgtag
    20881 gtaattcctg gtatatttat aatagtaatg ctaatatcaa taaaaatcag caagtaatgt
    20941 tgcctatgta tactaataat acaaagtcgt tatcgttaga tttgacgcca catacttacg
    21001 ctgttgttaa agaaaatcca aataatttac atattttatt gaataattac aggacagata
    21061 agacagctat gtgggcatta tcaggaaatt ttgatgcatc aaaaagttgg aagaaagaag
    21121 aattagagtt agcgaactgg ataagcaaaa attattccat caatcctgta gataatgact
    21181 ttaggacaac aacacttaca ttaaaagggc atactggtca taaacctcag ataaatataa
    21241 gtggcgataa aaatcattat acttatacag aaaattggga tgagaatacc catgtttata
    21301 ccattacggt taatcataat ggaatggtag agatgtctat aaatactgag gggacaggcc
    21361 cagtctcttt cccaacacca gataaattta atgatggtaa tttgaatata gcatatgcaa
    21421 aaccaacaac acaaagttct gtagattaca atggagaccc taatagagct gtggatggta
    21481 acagaaatgg taattttaac tctggttcgg taacacacac tagagcagat aatccctctt
    21541 ggtgggaagt cgatttgaaa aaaatggata aagttgggct tgttaaaatt tataatcgca
    21601 cagatgctga gactcaacgt ctatctaatt ttgatgtgat tctatatgac aataatagaa
    21661 acgaagttgc taagaaacat gttaataatt tgtcgggtga atctgttagt ctagatttca
    21721 aagaaaaagg agcaaggtat attaaagtta aattactaac gagtggagtg cctttgagtt
    21781 tagcagaagt agaggttttt agagaatcag atggtaagca atctgaagag gatatagata
    21841 aaataacaga agataaagta gtctctacaa ataaggtagc tactcaaagt tcaaccaatt
    21901 atgagggtgt agctgcttta gcagttgatg gtaataaaga tggagattac ggacatcatt
    21961 cggtgactca tactaaggca gattctaacg cttggtggca ggtcgatctg ggagaagagt
    22021 ttacggtttc taaagttgat atttataata gaacagatgc cgaacctcag cgtttatcta
    22081 attttgatgt tatttttcta tcttcatcag gagaagaagt ttttagaaga cattttgata
    22141 aagtagttga tggtttgtta tctttaaaag taccttctgt aggggctaag ctagtcaaaa
    22201 tagaattaaa atcagcagct attccgttaa gtttagcgga agttgaagtc tatggttcaa
    22261 agagaactcc gaagaaactt tctaatattg cattaaccaa agaaactcga cagagttcaa
    22321 cggattacaa tggtttttct cgtctagcag ttgatggaaa taaaaacgga gattatggtc
    22381 atcattcagt gactcatacc aaaggagatt ctccttcatg gtgggagata gatttagcac
    22441 aaaccgaaga attagaaaag ttaattattt ataatagaac agatgctgaa attcagagat
    22501 tatcaaattt tgatattatt atatatgatt caaataatca tgaagttttt aaacaacata
    22561 ttgacagttt agaaagcaat aatctatcca tagacttaaa agggctgaag ggaaaaaagg
    22621 ttagaatttc tttgagaaac gcaggaattc ctttaagttt ggcagaggta gaggtttata
    22681 cttataagta attttaaaaa ttatcatcgg tagtatgaaa gaaacagaaa aataagagga
    22741 aaatagtatg attcaacatc cacgtattgg gattcgtccg actattgatg gtcgtcgtca
    22801 aggtgtacgc gaatcacttg aagtacaaac aatgaacatg gctaaaagtg tggcagattt
    22861 gatttcaagc acattgaaat atccagatgg ggaacctgtg gaatgcgtga tttctccatc
    22921 taccattggt cgtgtaccag aggctgcagc ttcccatgag ttgttcaaaa aatcaaatgt
    22981 ttgcgcaaca attacagtta caccatgctg gtgttatggt agtgaaacta tggatatgtc
    23041 tccagatatt cctcatgcta tttggggatt taatgggaca gaacgcccag gagctgtcta
    23101 tcttgcagct gtactagctt catatgctca aaaagggatt ccagcctttg ggatttatgg
    23161 tagagacgtc caggaagcta gtgatacagc tattccagaa gatgtcaaag aaaaactttt
    23221 acgttatgcg cgtgcagctc ttgcaactgg cttgatgaga gacactgctt acctatcaat
    23281 gggtagtgtt tcgatgggga ttggcggttc tattgtaaat tcagatttct tccaagaata
    23341 cttaggaatg cgaaatgaat cggtagatat gacggagttc acgcgccgta tggaccgtgg
    23401 tatttacgac cctgaagagt ttgaacgtgc tatggtttgg gtaaaagaac atatcaaaga
    23461 aggagttgac cgaaatcgtg aggatttgat tctttctaaa gaagagaaag aaaaacaatg
    23521 ggaatttgtt attaagatgt tcatgattgg acgtgactta atggttggta acccaagact
    23581 tgctgaactt ggttttgaag aagaagcagt tggtcaccat gctttagtag ctggtttcca
    23641 aggtcaacgc cagtggacag accatttccc aaatggggac tttatggaaa ctttcctcaa
    23701 tactcagttt gattggaatg gtattcgaaa accatttgta tttgcgacag agaatgattc
    23761 actaaatggt gtgtctatgc tctttaatta tctattaaca aatactccac aaatctttgc
    23821 tgatgtgcgt acttattgga gtccagaggc tgttaaacgt gtaacgggac atactttaga
    23881 gggttgtgct gcagctggct tcttacatct aatcaactct ggttcttgta cattggatgg
    23941 tacagggcaa gctactcgag atggcaaacc tgttatgaaa ccattctggg agttggaaga
    24001 aagtgaagtg caggctatgc ttgaaaatac agacttccca ccagcaaacc gcgaatactt
    24061 ccgtggagga ggattctcaa ctcgtttctt gacgaagggg gatatgccag taacaatggt
    24121 acgtctcaat cttctaaaag gggttggtcc agtgctacaa attgcagaag gttatacact
    24181 tgaacttcct gaagatgttc accatacttt agataatcgt acagatccag gatggccaac
    24241 tacttggttt gctccacgtt tgacaggaaa aggtgctttc aagtctgtct atgacgtcat
    24301 gaataattgg ggagctaatc acggagccat aacatatgga cacattggag cagacttgat
    24361 taccttggct tctatgttga gaattcctgt caatatgcat aatgtacccg aagaagatat
    24421 ctttagacct aaaaattggt ccttatttgg aacagaagat ctagaatcag cagactatcg
    24481 tgcatgtcag ttattgggac cactacataa ataaaacttg tttatatagg aggtgaactt
    24541 acgtccctcc tatcctttta aaaagatttg ttaaacaatt cacaaataat tgaaaacgaa
    24601 tacaaaaagt aatataatga tgttaaatag atagcgcgga ggcgcaggag gaaaattata
    24661 tggctacatt ttatgttccg gcagtcaacc ttattggaaa aggtgttgta aatgaagtgg
    24721 gtccttatat caaggaactt ggctataaaa aggcactttt ggttacagat aagtacatcg
    24781 aaggcagtga tattttacct aaggttttaa aaccactgga tacagaagga atcgaatatg
    24841 tcatctttag cgatgtagag ccaaacccta cttgtaaaaa tgtcacagat ggggtagctg
    24901 ctttgcaaga acatggctgt gactttatca tcagtcttgg cgggggttct ccacaggatg
    24961 cagctagttg tatttctatc atggctacaa atggtggaaa accacaggat tatgaagggc
    25021 ttcataagtc tgctaaaaaa ggcttgccag ttgtggctat caatacaacg gcaggaactt
    25081 ctgcagaaat cactattaac tatgtgatta ctgatgaaga acgcaaggtt aagatggtaa
    25141 tggttgacaa gaatagcctt gctcttatct ctgttaatga cccggaactc atgctttcca
    25201 aacctaaagg cctgactgct gctactggta tggatgctct gactcacgct gttgaagctt
    25261 tggtaacacc tggtgcttat gatgtaacca agaaactgtc tattggtgct attgagctta
    25321 tcaaggaata tcttcctcgt gctgtagaaa atggacatga tattgaagcg cgtgaaggta
    25381 tggtcaatgc catcttcctt ggtggtatga gctttaataa tgctggtctt ggttatgttc
    25441 actcaatggc tcaccaactc ggtgcagtat ataatttgcc acatggtgtt tgctgtgcca
    25501 tgttgctacc agttatagaa cgtgaaaatg ctaaacgtgt accagaagct ttccgcaatg
    25561 ttgccaaagc cttgggactt catgtagaag gtaaatcaga tcaagaatgt gccgattatg
    25621 cgattgttga gattgagaag ctttctgaga cagtaggtat tcctaagaaa ctgactgaac
    25681 ttggtattga agaaaaagat ttcgactttg aatacctttc taagaatgcc ttgattgatg
    25741 cctgcgcacc aggaaatcca tttatgccaa ccttagaaga aacgattgcc ttttataaag
    25801 agttatttta gcaagagatt ggacgacaat aggacaattc acctctaatt attgacattt
    25861 caggaaaaat cgcagtaaaa acggcacagc cttctttaaa tgtgctataa tactagaaaa
    25921 atacttgtgg aggttccatt atggcaatat ttttcatgat ttttctgatt gtttgtgtgc
    25981 tcctattggt gatagtcaca ctgagtacag tttatgtggt tcgtcagcag tcggtggcga
    26041 ttattgaacg ctttgggaaa taccaaaagg ttgccaatag cggtattcat attcgcttgc
    26101 cttttgggat tgactcgatt gcagcacgga ttcagttgcg cttgttgcaa agtgatattg
    26161 tggttgagac taagaccaag gacaatgtgt tcgttatgat gaatgtagcg actcagtacc
    26221 gtgtcaacga gcagagcgtg acagatgctt actataaact catacgtcca gaatctcaga
    26281 ttaaatctta tatcgaagat gctcttcgct cttctgttcc aaaattaacc ttggatgaat
    26341 tgtttgagaa aaaagatgag attgcccttg aagttcaaca ccaagtagca gaagaaatga
    26401 ccacttacgg ctacattatc gtgaaaacct tgattaccaa ggtcgaacca gatgcagaag
    26461 ttaagcaatc catgaatgaa atcaatgcgg cgcaacgtaa gcgggtcgca gcacaagaat
    26521 tggcggaagc tgacaagatt aaaattgtca ctgcagctga agcagaagca gaaaaagacc
    26581 gccttcatgg tgtggggatt gcccaacaac gtaaggcgat tgtggatgga ttggcagagt
    26641 ctatcaccga actcaaggaa gtcaatgttg gcatgacaga agaacaaatc atgtctatcc
    26701 tcttgaccaa ccagtatttg gataccttga atacctttgc ctctaaagga aatcaaacca
    26761 tctttttacc aaatacgcca aatggtgtgg atgatatccg aacacaaatc ttgtcagccc
    26821 ttcgcgctga gaagaaataa tagactaata ctcttcgaaa atctcttcaa accacgtcag
    26881 cgtcgccttg ccgtatattt gagctgactt cgtcagttct atctgcaacc tcaaaacagt
    26941 gttttgagca acctgtggct agtttcctag tttgctattt gattttcatt gagtacaaag
    27001 agcttggcaa caggctcttt ttgtattgcg tttattaaga aaaacaaaaa acatagatat
    27061 acatttaact aaaaattatt gtatgttacc tcccttaatt aggaatgata agggaataac
    27121 tagaaagatt tgtgaataca aactatttct gatatacaaa atatacagta ataatgaatg
    27181 atgggagatg ggatgaaaga atttcaattt gagagaaagc agcgtttttc tttgaggaaa
    27241 tatgcaatag gagcttgttc ggtcttgcta ggaacgagtt tattttttgc tggtatgggt
    27301 gatcagcctg tacaggatac agaaacgagt tcagcactaa tttcaagtca ttatttggat
    27361 gagcatgatt tatctgaaaa gctgaaatct gagttgcaat ggtttgaatt agaaaacaag
    27421 cttttgaact tatgggagca ttaggttact atgaaggatt tgttccttat gtttcaaatc
    27481 aatacaaaaa ccaagctgaa gaagaaggca aaccgctatc tgataaatat attttcgaaa
    27541 aaatcttagg aaaaacatat gcagccttca aaaaagatca aattaatgag cgtgtcgaga
    27601 aattaggtaa gttaaaacct attacaataa attacaacgg aaaatcagaa gtaattgata
    27661 gtaaagaaaa attacaagag cttatgaata aagccgttaa agacgaagtg gctcaaatat
    27721 agtaaaatga aataagaata ggacaaatcg ttcaggacag tcaaatcgat ttctaaaaat
    27781 gttttagaag tagaggtgta ctattctagt ttcaatatac tataaaatca ggcaatacca
    27841 cggctaaaaa gtttgagttt atcgaaacac cagtgcaaaa actgaaaaaa tcgatttata
    27901 aagctcatct caaagattca gatgacttta gaccagaaac atccac
//
LOCUS       DBEJHE010000025        25503 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC4 isolate 671759
            SAMN38261586-rid24793303.denovo.25, whole genome shotgun sequence.
ACCESSION   DBEJHE010000025 DBEJHE010000000
VERSION     DBEJHE010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261586
            Sequence Read Archive: SRR26833752
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 25503)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25503)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576136.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576136.1
            Genome Coverage       :: 109x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 19:48:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,067
            CDSs (total)                      :: 2,029
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 131
            CDSs (without protein)            :: 131
            Pseudo Genes (ambiguous residues) :: 0 of 131
            Pseudo Genes (frameshifted)       :: 64 of 131
            Pseudo Genes (incomplete)         :: 59 of 131
            Pseudo Genes (internal stop)      :: 46 of 131
            Pseudo Genes (multiple problems)  :: 32 of 131
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25503
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261586-rid24793303.denovo.25"
                     /strain="GPSC4"
                     /isolate="671759"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(1..710)
                     /locus_tag="ACL3EZ_001481"
                     /pseudo
     CDS             complement(1..710)
                     /locus_tag="ACL3EZ_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            1258..3816
                     /locus_tag="ACL3EZ_001482"
     CDS             1258..3816
                     /locus_tag="ACL3EZ_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000442363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HGR0393032.1"
                     /translation="MERSQFEEMFQLQSSRLTTQEKLQLFTSVFAGRYDVYAKNFINE
                     QGKIQYFPSYDYGWKQLPPEKRSFQTLTNSVLKSHFRGEAAIGIFPMHLDDSCYFLVL
                     DLDEGDWKEAGLTIRRIARERQMEAHLEISRSGYGLHIWFFFEEAILSRKARLFGKKL
                     LELAMQESMQLSFDSFDRMFPNQDVLPKGGFDNLISLPFQGEAYHQGRTVFVDEQFQP
                     YEDQWRYLQEIQKISTAKVALLIQEELGKQELDKELKIVLSNMIQLEKSSVTPKTLFF
                     LKNMASFSNPEFYLKQAMRQPTYQIPERMYLFGESDHYLWLPRGLLYPLQDKFKQVSV
                     EDRRKVQRSISVEFKGELTFEQELALSDMTSKENGLLHAETGFGKTVLGAALISERKT
                     KTIILVHNKQLLDQWLDRLNCFLTFEEEEAIRYTASGREKVIGYVGQYGGTKKWLSKL
                     VDVVMIQSLFKLENSQSLLDEYEMMIVDECHHVSALMFEKVVAQFRGKYLYGLTATPE
                     RKNGHEPIVFQRIGEILHTADKRETDFKRQLQLRFTSFGHLEIEKTKASNFIQLSDWI
                     ATDSARNQLILKDILAQVAEGRNILVLVNRIQQIDVFEKLLKEKEVDGCYIISGKTKV
                     RERTSLLETLEQLDKGFVLLSTGKYIGEGFDLPQLDTLILAAPFSWKNNLIQYAGRIH
                     RNYKDKSLVRIFDYVDIHVPYLEKMFQKRQVAYRKMDYRVIEGEEKQFVYVDSRYEKV
                     LREDLAGERQECLLILPYVHQTKLMNFLKEFRISQIEICIPETVANKAWLDQLKSQKI
                     KVSFTQSKIVTPILLVNKTIVWYGAMPLLGKVDEMTILRLESASIVSELVAGLR"
     gene            4116..4955
                     /gene="licT"
                     /locus_tag="ACL3EZ_001483"
     CDS             4116..4955
                     /gene="licT"
                     /locus_tag="ACL3EZ_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator LicT"
                     /protein_id="HGR0393033.1"
                     /translation="MIIKRILNHNAVIAQSKKDIDILLFGRGIAFGRKTGDKVNPIDI
                     EKSFFLKNRDNMTRFTEMFINVPLELVYITEKIINLGKITLGNNFDEIIYINLTDHIS
                     SSIERYKEGIIISNPLRWEISKYYKEEFELGKRALQIIKKELGIELPIDEAAFIALHF
                     VNANLENNFQESYKITEIIMGIEKIIQDFYCTEFNQDSIDYYRFITHIKLFAHRLVEN
                     TTYCDDDDEDLLALMKNKYPREYECGEQVAMFIQTEYNYLLTSSELVYLMAHIRRLTK
                     NLD"
     gene            4973..6811
                     /locus_tag="ACL3EZ_001484"
     CDS             4973..6811
                     /locus_tag="ACL3EZ_001484"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
                     /protein_id="HGR0393034.1"
                     /translation="MSYKDTVQKILDVIGGEKNVNRVTHCVTRLRLELKDENLVNDDD
                     VKKIPGVIGIMKKNGQYQIILGNDVANYYKEFVKLGNFESDSVVQGHKGNILERIIEY
                     IAGSMTPIIPAMLGGGMLKVLVIILPMLGILQSDSQTIAFLTFFGDAPYYFLPLLLAY
                     SASQKLKVTSTLAMSVAGVLLHPNFVQMVQSGNPLSLFGVPVTPASYGSSVVPILIMV
                     WLMKYIEKMIAKLTPAVTKSFLQPTLVLLVSSCIALVVVGPIGVIVGEGLSNLVGQMY
                     GVAGWLTLAILGAIMPFIVMTGMHWAFAPIFLAASIATPDVLILPAMLGSNLAQGAAS
                     MAVALKSKNNNTKQIAFAAGFSALLAGITEPALYGVTLKYKKPLYAAMIGGGLAGLFA
                     GLTSVKAYLFAVPSLIALPQFIYSDVPSNIVNALIVAVISVVITFVLAYIFGIDEEES
                     SSNLEVKAGVSNKKMIFSPISGEIIPLSDVQDKTFSDKLIGDGVAIIPSEGKVYAPFD
                     GKITNIFPTKHAIGLKSDEGVELLIHIGLDTVELKGQGFISHVEEGDRVFKNQLIFEM
                     DLNLIKTKGYETVTPVIVTNTNDFLDVLVLPNNQTIEHSKELLVIL"
     gene            6824..8239
                     /locus_tag="ACL3EZ_001485"
     CDS             6824..8239
                     /locus_tag="ACL3EZ_001485"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HGR0393035.1"
                     /translation="MTIFPDDFLWGGAVAANQVEGAYNEDGKGLSVQDVLPKGGLGEA
                     TENPTEDNLKLIGIDFYHKYKEDISLFSEMGFNVFRTSIAWSRIFPKGDEEEPNEAGL
                     KYYDELFDELHAHGIEPLVTLSHYETPLYLARKYHGWIDRRMIHFYEKFARTVLERYK
                     DKVKYWLTFNEVNSVLELPFTSGGIDIPKENLSKQELYQAIHHELVASSLVTKIAREI
                     NSEFKVGCMVLAMPAYPMTPNPKDVWATHEYENLNYLFSDVHVRGYYPNYAKRYFKEN
                     DINIEFAAEDAELLKNYTVDFLSFSYYMSVTQSALPTQYNSGEGNIIGGLVNPYLESS
                     EWGWQIDPIGLRIILNRYYDRYQIPLFIVENGLGAKDQLIKDEFNNLTVQDDYRIQYM
                     KEHLLQVAEALQDGVEIMGYTSWGCIDCVSMSTAQLSKRYGLIYVDRNDDGNGTFNRY
                     KKMSFTWYKGVIESNGESLFK"
     gene            8831..9877
                     /gene="pheS"
                     /locus_tag="ACL3EZ_001486"
     CDS             8831..9877
                     /gene="pheS"
                     /locus_tag="ACL3EZ_001486"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006432 - phenylalanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HGR0393036.1"
                     /translation="MSTIEEQLKALREETLTSLKQITAGNEKEMQDLRVSVLGKKGSL
                     TEILKGMKDVSAEMRPIIGKHVNEARDVLTAAFEETAKLLEEKKVAAQLASESIDVTL
                     PGRPVATGHRHVLTQTSEEIEDIFIGMGYQVVDGFEVEQDYYNFERMNLPKDHPARDM
                     QDTFYITEEILLRTHTSPVQARAMDAHDFSKGPLKMISPGRVFRRDTDDATHSHQFHQ
                     IEGLVVGKNISMADLQGTLQLIVQKMFGEERQIRLRPSYFPFTEPSVEVDVSCFKCGG
                     EGCNVCKKTGWIEIMGAGMVHPRVLEMSGIDATVYSGFAFGLGQERVAMLRYGINDIR
                     GFYQGDVRFSEQFK"
     gene            9877..10386
                     /locus_tag="ACL3EZ_001487"
     CDS             9877..10386
                     /locus_tag="ACL3EZ_001487"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR0393037.1"
                     /translation="MIRKVEMADVEVLAKIAKQAFRETFAYDNTEEQLQEYFEEAYSL
                     KTLSTELGNPDSETYFIMHEEEIAGFLKVNWGSAQTERELEDAFEIQRLYVLQKFQGF
                     GLGKQLFEFALELATKNSFSWAWLGVWEHNTKAQAFYNRYGFEKFSQHHFMVGQKVDT
                     DWLLRKKLR"
     gene            10463..12865
                     /gene="pheT"
                     /locus_tag="ACL3EZ_001488"
     CDS             10463..12865
                     /gene="pheT"
                     /locus_tag="ACL3EZ_001488"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006432 - phenylalanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HGR0393038.1"
                     /translation="MLISYKWLKELVDIDVPSQELAEKMSTTGIEVEGVESPAAGLSK
                     IVVGEVLSCEDVPETHLHVCQVNVGEEERQIVCGAPNVRAGIKVMVALPGARIADNYK
                     IKKGKIRGLESLGMICSLGELGISDSVVPKEFADGIQILPEDAVPGEEVFSYLDLDDE
                     IIELSITPNRADALSMCGVAHEVAAIYDKAVNFKEFTLTETNEAAADALSVSIETDKA
                     PYYAARILDNVTIAPSPQWLQNLLMNEGIRPINNVVDVTNYILLYFGQPMHAFDLDNF
                     EGTDIRVREARAGEKLVTLDGEERDLDVNDLVITVADKPVALAGVMGGQATEISEKSS
                     RVVLEAAVFNGKSIRKTSGRLNLRSESSSRFEKGINVATVNEALDAAASLIAELAGAT
                     VRKGIVSAGELDTSDVEVSSTLADVNRVLGTELSYADVEDVFRRLGFGLSGNADSFTV
                     RVPRRRWDITIEADLFEEIARIYGYDRLPTSLPKDDGTAGELTATQKLRRQVRTIAEG
                     AGLTEIITYTLTTPEKAVEFTAQPSNLTELMWPMTVDRSVLRQNMISGILDTVAYNVA
                     RKNKNLALYEIGKVFEQTGNPKEELPNEINSFAFALTGLVAEKDFQTAAVPVDFFYAK
                     GILEALFTRLGLQVTYTATSEIASLHPGRTAVISFGDQVLGFLGQVHPVTAKAYDIPE
                     TYVAELNLSAIEAALQPATPFVEITKFPAVSRDVALLLKAEVTHQEVVDAIQAAGVKR
                     LTDIKLFDVFSGEKLGLGMKSMAYSLTFQNPEDSLTDEEVARYMEKIQASLEEKVNAE
                     VR"
     gene            complement(12933..13934)
                     /locus_tag="ACL3EZ_001489"
     CDS             complement(12933..13934)
                     /locus_tag="ACL3EZ_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000597989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HGR0393039.1"
                     /translation="MIKTFLSALSVILFSIPIITYSFFPSSNLNIWLSTQPILAQIYA
                     FPLATATMAAILSFVFFSLSFYKKNKQIRFYSGILLLLSLILLLFGTDKTLSSASNKT
                     KTLKLVTWNVANQIEAQHIERIFSHFDADMAIFPELATNIRGEQENQRIKLLFHQVGL
                     SMANYDIFTSPPTNSGIAPVTVIVKKSYGFYTEAKTFHTTRFGTIVLHSRKQNIPDII
                     ALHTAPPLPGLMEIWKQDLNIIHNQLASKYPKAIIAGDFNATMRHGALAKISSHRDAL
                     NVLPPFERGTWNSQSPKLFNATIDHILLPKNHYYVKDLDIVSFQNSDHRCIFTEITF"
     gene            14090..14536
                     /locus_tag="ACL3EZ_001490"
                     /pseudo
     CDS             14090..14536
                     /locus_tag="ACL3EZ_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            14662..14928
                     /locus_tag="ACL3EZ_001491"
     CDS             14662..14928
                     /locus_tag="ACL3EZ_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGR0393040.1"
                     /translation="MEGCPSELFSKEEILESDMRVAIMSELIEARYEQGISQKKLEEV
                     SGISQPVIARMETGESSLQLDTVLKVLTSLGKTLAVVPLEQGKS"
     gene            15189..17438
                     /gene="metE"
                     /locus_tag="ACL3EZ_001492"
     CDS             15189..17438
                     /gene="metE"
                     /locus_tag="ACL3EZ_001492"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003871 -
                     5-methyltetrahydropteroyltriglutamate-homocysteine
                     S-methyltransferase activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HGR0393041.1"
                     /translation="MSTTIIGFPRLGEFRELKFTTEKYFRKEISEEELLAAAKDLRAK
                     HWNIVKEKGITEIPSNDFSHYDNFLDAAFLFNVVPASVQNLDLSDLERYFALGRGYQG
                     EKGDVRALPMKKWFNTNYHYIVPKFEKDTQVKLAGHKIFDEFQEAKELGLNTRPVLVG
                     PFTFLQLSDFEEGVKADDFVDSLVVAYQEVFAKLAELGATRIQLDEAALVKDLTAEEK
                     ALFLNLYNKLLADKKGLEVLLQTYFGDVRDVYADLVNLPVDAIGLDFVEGKKTLELVK
                     GGFPADKTLYVGIVNGKNIWRNNYEKSLAVLEQIPAENIVLTSSCSLLHVPFTTANEE
                     FEPALLNHFAFAVEKLDEIRDLDAIRNGQGSEALAANKELFATERVGENAELRARIAG
                     LTDADYTRLPAFAEREAIQEEAFKLPALPTTTIGSFPQTKEVRAKRLAYRKGELSQKE
                     YDAFLAETIDEWIKWQEDIDFDVLVHGEFERNDMVEYFGQNLSGYLFSKNGWVQSYGM
                     RGVKPPIIWGDVTRLNSITVKWSSYAQSRTNKPVKGMLTGPVTILNWSFPREDISIKD
                     STLQIALAIKDEVLDLEAAGVKIIQIDEAALREKLPLRRSDWYEDYLDWAIPAFRLVH
                     STVAPDTQIHTHMCYSEFTDIIPAIDNMDADVISFEASRSNLEILDELKAKNFQTEVG
                     PGVYDIHSPRVPNEGEIDNTIEAILAKVPSKKVWINPDCGLKTRGIPETKESLIRLVE
                     AAKAAREKL"
     gene            17502..18368
                     /gene="metF"
                     /locus_tag="ACL3EZ_001493"
     CDS             17502..18368
                     /gene="metF"
                     /locus_tag="ACL3EZ_001493"
                     /EC_number="1.5.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000089969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0004489 - methylenetetrahydrofolate
                     reductase (NAD(P)H) activity [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="HGR0393042.1"
                     /translation="MSRQTPSLSFEVFPPNPAVGNGNIISALQDMQELAPHFISVTAS
                     NNKFNIKETTVRLADFIQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALR
                     GDIIPDVEPQKDFRYATDLIEFIKEQAPHFDIIGACYPEGHPDSPNQISDIQNLKKKV
                     DAGCSSLVTQLFFDNERFYDFQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIH
                     LPRKFKAILDKYEHDPESLRAAGLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQ
                     ATHALFNHQSLG"
     gene            19053..21266
                     /gene="pnp"
                     /locus_tag="ACL3EZ_001494"
     CDS             19053..21266
                     /gene="pnp"
                     /locus_tag="ACL3EZ_001494"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004654 - polyribonucleotide
                     nucleotidyltransferase activity [Evidence IEA];
                     GO_process: GO:0006402 - mRNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HGR0393043.1"
                     /translation="MAKQVFQTTFAGRELIVETGQVAKQANGSVVVRYGESTVLTAAV
                     MSKKMATGDFFPLQVNYEEKMYAAGKFPGGFMKREGRPSTDATLTARLIDRPIRPMFA
                     EGFRNEVQVINTVLSYDENASAPMAAMFGSSLALSISDIPFDGPIAGVQVGYVDGQII
                     INPSQEQAEQSLLELTVAGTKHAINMVESGAKELSEEIMLEALLKGHEAVKELIAFQE
                     EIVAAVGKEKAEVELLHVDAELQAEIIAAYNSDLQKAVQVEEKLAREAATQAVKDQVT
                     AVYEEKYANHEEFDRIMRDVAEILEQMEHAEVRRLITEDKVRPDGRKVDEIRPLDAVV
                     DFLPRVHGSGLFTRGQTQALSVLTLAPMGETQIIDGLDPEYKKRFMHHYNFPQYSVGE
                     TGRYGAPGRREIGHGALGERALAQVLPSLEEFPYAIRLVAEVLESNGSSSQASICAGT
                     LALMTGGVPIKAPVAGIAMGLISDGNNYTVLTDIQGLEDHFGDMDFKVAGTRDGITAL
                     QMDIKIQGITAEILTEALAQAKKARFEILDVIEATIPEVRPELAPTAPKIDTIKIDVD
                     KIKIVIGKGGETIDKIIAETGVKIDIDEEGNVSIYSSDQDAINRAKEIIAGLVREAKV
                     DEVYRAKVVRIEKFGAFVNLFDKTDALVHISEMAWTRTNRVEDLVEIGDEVDVKVIKI
                     DEKGRIDASMKALLPRPPKPEHDEKGEKSERPHRPRHHKDHKPKKEFTETPKDSE"
     gene            21282..21899
                     /gene="cysE"
                     /locus_tag="ACL3EZ_001495"
     CDS             21282..21899
                     /gene="cysE"
                     /locus_tag="ACL3EZ_001495"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000539958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0009001 - serine O-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HGR0393044.1"
                     /translation="MGWWHETIDIVKENDPAARTTLEVLLTYPGVKALAAHRLSHFLW
                     KYDFKLLARMHSQFWRFWTQIEIHPGAQIDSGVFIDHGSGLVIGETAIVEKGVLLYHG
                     VTLGGTGKDCGKRHPTVRKGALISAHAQVIGPVEIGENAKVGAAAVVVADVPSDVTVV
                     GIPAKIVRLHGKKDEPVIHEVEEKREYYVNKLEQAKDASHRSSGL"
     gene            21911..22795
                     /locus_tag="ACL3EZ_001496"
     CDS             21911..22795
                     /locus_tag="ACL3EZ_001496"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR0393045.1"
                     /translation="MIQARNKLSQEELSEAKKVINCCQNYDGTYRDPYLSNMLNFDPN
                     MPAFFLYYEKGKLVGLLTVYADDQDVEVTILVHPGHRRQGIARALFTSFERETASFPI
                     RSVTFQTERIFLENHPDFASNWGLIEDEETETWLGKDRRPYPLANVSHLEVLLADSSY
                     QDQISQLKFQAFSEEHESREVVDRYVAEALKDPESRLYILLKDGQVIGTCTVDLSTNT
                     NYFYGLAISEPERGKGYGSYLAKSLVNQLIEQNDKEFQIAVEDSNVGAKRLYEKIGFV
                     KQTQVVYLNEKGARDSEV"
     gene            22882..24225
                     /gene="cysS"
                     /locus_tag="ACL3EZ_001497"
     CDS             22882..24225
                     /gene="cysS"
                     /locus_tag="ACL3EZ_001497"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002916477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004817 - cysteine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006423 - cysteinyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HGR0393046.1"
                     /translation="MIKIYDTMSRDLREFVPIEDGKIKMYVCGPTVYNYIHVGNARST
                     VAFDTIRRYFEYRGYKVAYISNFTDVDDKIINRAREEGITPQEVADKYIAAFREDVTA
                     LGVKPATRHPRVVEFMADIIRFVEDLIEKGFAYESQGDVYFRVEKSHNYAKLANKTLE
                     DLELGASGRTDEETARKENPVDFALWKSSKPGEISWDSPWGPGRPGWHIECSVMSTEI
                     LGDTIDIHGGGADLEFPHHTNEIAQSEAKTGKAFANYWMHNGFVNIDNVKMSKSLGNF
                     ITVHDALKTLDGQVLRFFFATQHYRKPINFTEKAVRDAETNLKYLKNTYEQPFTGNVD
                     AQELQNFKDKFVAAMDEDFNAANGITVVFEMAKWINSGNYDASVKQALADMLEIFGIV
                     FVEEVLDAEIEDLIQKRQEARANRDFETADQIRDQLVTQGIKLLDTKDGVRWTRD"
     gene            24218..24604
                     /locus_tag="ACL3EZ_001498"
     CDS             24218..24604
                     /locus_tag="ACL3EZ_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HGR0393047.1"
                     /translation="MIDVNLINGIALAFEGDAVYSMYIRRHLILKGMTKPNKLHQEAT
                     KYVSAKAQARLIALMLEEQILTEKEEEIYKRGRNTNSHTKAKNADVVTYRMSTGFEAV
                     MGYLHMTENLERLESLVSWCIQKVEG"
     gene            24608..25492
                     /locus_tag="ACL3EZ_001499"
     CDS             24608..25492
                     /locus_tag="ACL3EZ_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGR0393048.1"
                     /translation="MRAKELQDWFPEARISDQPVEKEGYLTLPLASQQWILLEEAGLS
                     EREKQLVALLTQQEQARSLNPWYSYLVEGKGQAPQVFKKIQLVYCHLSYFQQENLTSW
                     LDMMRTLFPNCQTVLQVGAQDYVFVLQQDKYTSVRDILSDTIEAVEYDFGLRLSIMLG
                     QVWSQTGHQALSDLIKAERDLFKTWWRQGHQGVHTFSQLYLWSMGERLVDLKPIKECL
                     HQMILDQDQIQEIILSLWENSAVLTKTAQQLYLHRNSLQYKIDKWEELTGLQLKELTD
                     LTLCYQLILGSLSTIVGL"
BASE COUNT         7791 a         4533 c         5632 g         7547 t
ORIGIN      
        1 tatcactcag tttacggcta tcctgttgaa tgagtttcca gtagcgcttg atagccttgt
       61 attcatggga ttttcgatga aactgattca tgatttggac acgcacacga ctcatagcac
      121 ggctaagatg ttgtacaatg tgaaagcgaa gctgtttagc caagccatag taagggctaa
      181 acatatccat agtaataatt ttgacgcgac atcggacggc tctatcatat ttaagaaagt
      241 gatctcggat gacagcttgt gttcttccct caagaacagt gatgatatcg agcttttcaa
      301 aatcttgcgc aataaagctc atctccatct cccgattgaa acagtcactc cccggactgt
      361 ttcaacgtcc caagacataa tcttaggcag atttctaaaa ttacactcaa agtggaagtc
      421 attgagcttt cgaatgacag ttgaagttga aatggccagc tgatgggcaa tatcggtcat
      481 agaaatcttt tcaattaact tttgcgcaat cttttggttg ataatacgag gaatttggtg
      541 atttttcttg acgatagaag tttcagcgac catcattttc aagcaatgat agcacttaaa
      601 acgacgtttt ctaaggagaa ttctagtagg cataccagtc gtttcaaggt aaggaatttt
      661 atagggtctt taatgtctag taattttgtg ataaaatgta attgttccat atgattcttt
      721 ctaatgagtt gttttgtcgc ttttcattat agatcttatg ggactttttt tctacccaaa
      781 ataggctcca taatatccat agggaattta cccactacaa atattataga gcccaaagtt
      841 ttaggtcgct tgataatatg cgttttttga attttataga ctgctcgttt aaactctatt
      901 tacttcgtac cttctggagc gagacggaat attagtcaca tacaaaatga gtactattag
      961 gattttattt tcatgtacaa tttcagccag tcttgttata atcagcctat aggaatcaag
     1021 gaggtgactc ttatggctgt ttttgtgtct ttggatggaa ttgtggtaga agtccttgat
     1081 gtcttttctt cttttaatgg ggatagtgag tttttcttgt gtatagcatt ttgaatctgg
     1141 aataggacgc catgactgct aaaagatttc tataaattaa tttgattttc ctaatcaatt
     1201 tgttcatatc ttatttcatt ccactataaa cgtcttaaag acaagagtca gtttgttatg
     1261 gaacgctctc agttcgagga gatgttccaa cttcaaagta gtcgcttgac gacgcaagaa
     1321 aaattacaat tgtttacctc tgtgtttgct ggccgttatg atgtttatgc taagaatttt
     1381 atcaatgaac aagggaaaat tcagtatttt ccttcctatg attatggttg gaagcagttg
     1441 ccacctgaaa aacggagttt ccagacattg acgaactccg ttttgaaatc tcattttcgt
     1501 ggggaggcag ctatcggtat ctttcctatg cacttagatg atagctgtta ttttttggta
     1561 ctggatttgg atgaaggaga ttggaaagaa gctggtttaa ccattcgaag aatagccagg
     1621 gaacgccaga tggaagccca tttagagatt tctcgttcgg gttacggact ccatatttgg
     1681 ttcttctttg aggaagcgat tctgagtcga aaggctcgcc tgtttggaaa gaaactatta
     1741 gaattggcta tgcaggaaag tatgcaactg tcctttgatt cttttgatcg catgtttcca
     1801 aatcaggatg ttcttcctaa aggtggattt gataatttaa tttcccttcc ttttcaagga
     1861 gaagcttatc atcaagggcg aacggtcttt gtggatgaac agtttcagcc ttatgaagat
     1921 caatggaggt atctacaaga aattcagaag atttcaactg ctaaagtggc actgttaatc
     1981 caagaggagt taggcaagca agaattggac aaggagttga agatcgtctt atccaatatg
     2041 atccaacttg aaaaatcgtc tgtgacaccc aagacactgt ttttcttgaa aaatatggct
     2101 tcattttcta atcccgaatt ttatttaaag caggctatgc gacagccaac ctatcaaatt
     2161 cctgagagaa tgtatttatt tggagaatcc gatcattatt tatggttgcc aagaggtttg
     2221 ctgtatccat tgcaagataa atttaagcag gtatctgtgg aagataggag aaaggtacaa
     2281 aggtctatta gcgtggaatt taagggagaa ctcacttttg agcaagagtt agccctgtca
     2341 gatatgactt ctaaagaaaa tggtttactt catgcggaga ctggttttgg gaagaccgtt
     2401 ttaggtgctg ctcttatctc tgaacggaaa acaaaaacaa ttattctagt ccataataag
     2461 caactcttag accaatggct agatcgctta aactgctttt tgactttcga agaggaggag
     2521 gctatccgtt atacggcatc aggtcgtgaa aaggtaatcg gctatgttgg acagtacggt
     2581 gggactaaga aatggctgag taaactggtt gatgtcgtta tgattcaatc tctatttaag
     2641 ttggaaaata gtcaaagtct tttggatgag tatgagatga tgattgtgga tgagtgtcat
     2701 catgtctctg ccttgatgtt tgaaaaagtt gttgctcagt ttagagggaa gtatctttac
     2761 ggtttgacgg ctacgcctga gcgtaagaat ggtcatgagc ctattgtttt tcagagaatt
     2821 ggtgagatac tccatactgc tgataagagg gaaacggatt ttaaacggca attgcaatta
     2881 agattcactt cttttggtca tttggagatt gaaaagacca aagcaagtaa ttttatacag
     2941 ctcagtgatt ggattgctac agactcagcg aggaatcagt tgattctcaa ggatattcta
     3001 gcccaagtgg cagaaggacg gaatatcttg gttttagtta atcgaattca acagatagat
     3061 gtctttgaaa agttattgaa agagaaagag gttgatggct gttacattat tagcggaaaa
     3121 accaaagtcc gagaaagaac gagtttactg gagacgttag aacagttaga taaagggttt
     3181 gttttgttgt ctactggaaa atacattggc gaaggttttg acttacctca gttggacacg
     3241 cttatcttgg cagcaccctt ttcttggaaa aataatttaa ttcagtatgc aggtcggatt
     3301 catagaaact acaaggataa gtctttggtg cgtattttcg attatgtgga tattcatgtt
     3361 ccttatttag aaaagatgtt tcagaaacga caagtagctt atcgaaagat ggattatcgt
     3421 gtcatcgagg gtgaggagaa acaattcgtt tatgttgata gtagatatga gaaggtgttg
     3481 agagaggact tagcagggga aagacaggaa tgtctgctta ttttacctta tgtgcaccag
     3541 acaaaactga tgaattttct aaaagaattt aggattagtc aaattgagat atgtatacca
     3601 gagacggttg caaataaagc atggctagac cagttgaaga gccagaaaat taaagtgtct
     3661 tttactcaat caaaaatagt aacgcctatt cttttggtga ataagactat tgtttggtat
     3721 ggtgcaatgc cattattagg gaaggtagat gagatgacca tattacgttt ggaatcagct
     3781 agtatagttt ctgaactagt ggcaggttta cgatagagaa aatttttaaa aatttctatg
     3841 tatgattttc atttctttag tgagactgtt gccattatca cattcgaatc acacaaaata
     3901 aaaaaatttt tataagtact tgacaaatag attgaaatat cataaaataa aaacggttac
     3961 agagttatta attatttaag cttcatgtca ccattaaaaa ttgaaataaa aggatgttat
     4021 cactaataca agtgagcagg aacctattta atcacatcag aagaagtttc ttgatgtttt
     4081 taagtaggtt ccttttattt taaaagggaa attttatgat cataaaacga atactaaacc
     4141 acaatgccgt aattgcgcaa agtaaaaaag atatcgatat tcttcttttt ggaaggggaa
     4201 tagcttttgg aagaaaaact ggagataaag taaatccaat tgatattgag aaaagttttt
     4261 ttctcaaaaa tagagataat atgacccgtt ttacagagat gtttattaac gttcctttgg
     4321 agttggtgta catcaccgaa aaaataatta acctaggtaa aataacattg ggtaataatt
     4381 ttgatgaaat tatctatatt aatttaacgg atcatatttc ttcgagcata gaacgttata
     4441 aagaagggat tattatttcg aatcccctac gctgggaaat atcgaaatat tataaagaag
     4501 aatttgaact tgggaaaagg gctttacaaa taataaaaaa agagttaggt attgaacttc
     4561 caattgacga agctgcattc atagcgctac attttgttaa tgctaattta gaaaataatt
     4621 ttcaagagtc gtataaaatc actgaaataa ttatgggaat tgagaaaatc attcaagatt
     4681 tctattgtac tgagtttaac caagattcta ttgattatta tagattcata actcatataa
     4741 aattatttgc ccatcgcttg gttgaaaata caacttattg tgacgatgat gatgaagact
     4801 tgttagcatt aatgaaaaat aaatatccta gagaatatga atgtggtgaa caggtggcaa
     4861 tgtttataca aacggagtac aattatttgc tgacttctag tgaattagtt tatttgatgg
     4921 ctcatattcg tcgcttaaca aaaaatttag attaatagaa taggagaata ccatgagtta
     4981 taaagatacg gtacaaaaaa tcctcgatgt aattggaggt gaaaaaaatg tcaatagagt
     5041 tacccattgt gtaacacgtt taagattaga attaaaagat gaaaatttag tcaatgatga
     5101 tgatgtgaag aagataccag gtgtaatagg tattatgaaa aagaatggac aatatcaaat
     5161 tatacttggt aatgatgtag ctaattatta taaagaattc gttaaacttg gcaattttga
     5221 atccgattca gttgttcaag ggcacaaagg gaatatttta gaaagaatca ttgagtatat
     5281 cgctggttcc atgactccaa tcattccagc aatgttaggg ggaggtatgc tgaaagtctt
     5341 ggtaattatt ttaccaatgc ttggtatatt gcaatcagat tctcagacta ttgctttttt
     5401 gacatttttt ggggatgctc catattattt cttaccgctg ttattagctt attctgcatc
     5461 acaaaaatta aaagtaacat ctacattagc tatgtctgta gcaggtgtac ttctccatcc
     5521 aaattttgtt caaatggtgc aatcagggaa tcctcttagt ttatttggtg tacctgtgac
     5581 accagctagt tatggttcgt cagtcgttcc aattcttatt atggtttggt tgatgaaata
     5641 tattgaaaaa atgattgcta aattaacacc agctgttact aagagttttt tgcaacctac
     5701 gctagtatta ttagtatcaa gctgtattgc cttagttgta gtcgggccta ttggagtaat
     5761 tgttggtgaa ggattatcaa atctagttgg gcaaatgtat ggtgtagctg gatggcttac
     5821 attagctatt cttggtgcta ttatgccatt tattgttatg actggaatgc attgggcttt
     5881 tgcacctatt tttttggcgg catctattgc tactccagac gtattaattc ttccagcaat
     5941 gttagggtca aacttagctc aaggggctgc ttcgatggct gttgcattaa agagtaaaaa
     6001 taataataca aaacaaattg cttttgcagc aggtttctca gccttacttg cagggattac
     6061 cgaacctgca ttatatggtg tgactttaaa atataaaaaa ccgctttatg cagctatgat
     6121 tggtggtgga ttagcgggat tatttgcagg tcttactagt gttaaagcgt atctatttgc
     6181 tgtcccatct ttgatagcgt tgcctcaatt tatttattct gatgtgccat caaatattgt
     6241 aaatgcttta attgtggcgg ttatttcggt tgttattacc tttgtattag cttatatatt
     6301 tggaatcgat gaagaagaga gttctagcaa tttagaagtt aaagctggag tttcaaataa
     6361 aaaaatgata ttttctccta tatcaggaga aatcattccg ttaagcgatg tccaggataa
     6421 aacattttca gataaactaa ttggagacgg agtagcgatt attccaagtg aaggtaaggt
     6481 ttatgcacca tttgatggga aaattacaaa tatttttccg actaagcacg caattggatt
     6541 gaagagtgat gagggtgttg agttactaat tcatattgga ttagatactg ttgagctaaa
     6601 aggtcaaggt tttattagtc atgtagaaga aggagacaga gttttcaaaa atcagttgat
     6661 ttttgaaatg gacttgaatt taatcaagac taaaggctac gaaacagtta caccagtaat
     6721 tgtaacgaat accaatgatt ttctagatgt attagtatta cctaataatc agacaatcga
     6781 gcattctaag gaattactgg taatattata atggaggaaa gttatgacca tttttccaga
     6841 tgattttctt tggggtggag ctgttgcagc taatcaagta gagggagcat ataatgaaga
     6901 tggtaagggc ttatcagttc aggatgtgtt acccaaaggt ggattaggag aagcaacaga
     6961 aaatcctaca gaagataact taaaattgat aggtattgat ttttatcata aatataagga
     7021 agatatatcc ttgttttctg aaatgggctt taatgttttt cgtacttcta ttgcatggag
     7081 tagaattttt ccaaaaggag atgaggaaga acctaacgaa gctgggttga aatattatga
     7141 tgaattgttt gatgaactac atgctcacgg gatagaacca cttgtaactc tttcacacta
     7201 tgagactcca ttatatttag caagaaaata tcatggatgg attgatagga gaatgattca
     7261 tttttatgaa aaatttgctc gaacagtttt agaaaggtat aaagataaag ttaaatattg
     7321 gcttacattt aacgaagtaa actctgtttt ggaattaccg tttactagtg gaggaataga
     7381 tatacctaag gagaatcttt cgaaacaaga attatatcaa gctatacatc atgaattagt
     7441 cgcctcgagt ttggttacaa aaattgctcg tgagattaat tcagagttta aggtggggtg
     7501 tatggtatta gctatgccag cttatccaat gactccaaat ccaaaagatg tatgggcgac
     7561 tcatgagtat gagaatctaa attatctatt ttcagatgtg catgttagag gttattatcc
     7621 gaattatgca aaaagatatt ttaaggaaaa tgacattaac atagagtttg cagctgaaga
     7681 tgcagagtta ttaaaaaatt atactgtaga ttttttatcc tttagctatt acatgagtgt
     7741 gactcaatct gctcttccaa cacagtataa ttcaggagaa gggaatatta ttggtggttt
     7801 agtaaatcct tatttagagt cttctgagtg gggatggcaa attgatccaa ttggactacg
     7861 tataatttta aatagatatt atgaccgtta tcaaattcca ttatttatag tggaaaacgg
     7921 attaggtgct aaagatcaac taataaaaga tgaatttaat aacttaacag tccaagatga
     7981 ttatagaatt cagtatatga aagaacattt attgcaagta gctgaagctc tacaagatgg
     8041 tgtggaaatt atgggctata cgtcttgggg atgtattgac tgcgtttcta tgtccactgc
     8101 acagctttct aagaggtacg gtctcattta tgttgatcga aatgatgatg gaaatggcac
     8161 attcaatcga tataagaaaa tgtcctttac ttggtataaa ggagtgattg aatcaaatgg
     8221 agaatcctta ttcaaatagt ttgtttattg atgattagat attatcacgg ttaaggcagc
     8281 atctcattaa atatgaaata aagaggtttg gaagacatca aattctaaac ctctttattt
     8341 tataggggga ttaattaatt taattttgtt acagagagcc gattataaat agttaactta
     8401 ggatagattg gttatatata gtagactgaa tctaaaatag tacgaaacaa ttgctaaaac
     8461 atttatagaa attaatttta ctttcccaat cgatttgttt tcatcttatt tcaatccgct
     8521 ataaagttag ataagaataa gctaacaagc agaagtaaga taggtcttgc aagaatggta
     8581 aaaatctgat aaactaagtg gtaattgaat agaaatctga aagactagta gcccaaggga
     8641 agtatatcag ggaggagagc cgtgactgca agctctctat atgaaagctg ggtgaattca
     8701 cttgcgcatg gatttagaaa tgaaggtctg acttgtcaga tgaaaacgga tggtaccgcg
     8761 tgtcaacgct ccgagtggag tttttggcat gtggttttct ttttatctac gagagactga
     8821 tggaggaaat atgtcaacta ttgaagaaca attaaaagcg cttcgcgaag aaacgctgac
     8881 tagcttgaag cagattactg ctggaaatga aaaagagatg caagatttgc gtgtctctgt
     8941 ccttggtaaa aagggttcgc tcactgaaat cctcaaaggg atgaaagatg tttctgctga
     9001 gatgcgtcca atcatcggga aacacgtcaa tgaagctcgt gatgtcttga cagctgcttt
     9061 tgaagaaaca gctaagctct tggaagaaaa gaaagtcgcg gctcaactgg ctagcgagag
     9121 tatcgatgtg acgcttccag gtcgtccagt tgcgactggt caccgtcacg ttttgacaca
     9181 aaccagtgaa gaaatcgaag atatcttcat cggtatgggt tatcaagtcg tggatggttt
     9241 tgaagtggag caagactact ataactttga acgtatgaac cttccaaaag accacccagc
     9301 tcgtgatatg caggatactt tctatatcac tgaagaaatc ttgctccgta cccacacgtc
     9361 tccagttcag gcgcgtgcta tggatgccca tgatttttct aaaggtcctt tgaagatgat
     9421 ctcgccaggg cgtgtcttcc gtcgcgatac ggacgatgcg acccacagtc accaattcca
     9481 ccaaatcgaa ggcttggtag ttgggaaaaa tatctctatg gctgatcttc aaggaacgct
     9541 tcagttgatt gtccaaaaaa tgtttggtga agagcgtcaa attcgtttgc gtccatctta
     9601 cttcccattc acagagccat ctgttgaggt ggatgtttct tgcttcaagt gtggtggaga
     9661 aggctgtaac gtatgtaaga aaacaggttg gatcgaaatt atgggagccg gtatggttca
     9721 cccacgtgtc cttgaaatga gtggtatcga tgcgactgta tactctggtt ttgcctttgg
     9781 tcttggacaa gagcgtgtag ctatgctccg ttatggaatc aacgatatcc gtggattcta
     9841 ccaaggagat gtccgcttct cagaacagtt taaataatga ttagaaaagt agaaatggca
     9901 gatgttgagg tgttggctaa aattgccaaa caagcctttc gtgaaacctt tgcgtatgat
     9961 aatacggaag agcagttaca ggaatacttt gaagaggctt atagtctgaa aactttgtca
    10021 actgagttgg gaaatcctga ctctgaaacc tatttcatta tgcatgagga ggagatagct
    10081 ggttttctca aagtcaactg gggaagtgct caaactgaga gagaattaga ggacgctttt
    10141 gaaattcaac gcctctatgt gctacaaaaa ttccaaggat ttggactagg taagcaactg
    10201 tttgaattcg cacttgaact tgctacaaaa aatagttttt cttgggcttg gctaggtgtt
    10261 tgggagcata atacaaaagc tcaagcgttt tataatcgat atggttttga aaaatttagc
    10321 caacatcatt ttatggttgg tcaaaaagta gatacggatt ggttactgag aaagaaatta
    10381 aggtaagaag aggattcttc tattgaaatg ataggaaagg aaaagaacca gtgtggcaat
    10441 ggtcattctg gagaactaaa ttatgcttat atcttataaa tggttaaaag aattggtgga
    10501 cattgatgtg ccatcacaag agttggctga aaaaatgtca actacaggaa tcgaggtaga
    10561 gggtgtcgaa tcaccagctg ctggtctctc aaaaattgtc gtcggtgagg tcttgtcttg
    10621 cgaagatgtg ccagagactc acctccatgt ttgtcaggtt aacgttggcg aagaagagcg
    10681 tcagatcgtt tgtggtgccc caaatgtgcg tgctgggatc aaggtcatgg tggctcttcc
    10741 aggagctcgt atcgctgata actacaaaat caaaaaagga aaaatccgtg gtttggagtc
    10801 acttggaatg atctgttcac ttggtgaatt gggaatttct gactcagttg tgcctaagga
    10861 attcgcagat ggcatccaaa tcttgcctga agatgccgtg ccaggtgagg aagtcttttc
    10921 ttacctagac ttggatgatg aaatcatcga actttccatc acaccaaacc gtgcagatgc
    10981 cctttctatg tgtggagtgg ctcacgaagt ggcagccatc tatgacaagg cagtcaactt
    11041 taaagaattt actctaacag aaactaatga agctgcggca gatgcccttt ctgtcagcat
    11101 tgagacagac aaggcgcctt actatgcagc tcgtatcttg gacaatgtga ccatcgcacc
    11161 aagtccacaa tggttgcaaa atcttctcat gaacgaagga atccgtccca tcaataacgt
    11221 agtggacgtg accaactaca tcctgctcta ttttggtcaa ccaatgcatg cctttgactt
    11281 ggataacttt gaagggactg acatccgtgt gcgtgaagcg cgtgctggtg aaaaattggt
    11341 gaccttggac ggtgaagaac gtgacttgga cgtgaatgac ctagtcatca ctgtcgcaga
    11401 caagccagta gcccttgcag gtgtcatggg tggtcaagca acagaaatct ctgaaaaatc
    11461 tagtcgtgtt gtccttgaag ctgctgtttt caatggcaaa tctatccgta agacaagtgg
    11521 tcgcctgaac cttcgttctg agtcatcttc tcgctttgaa aaaggaatta atgtggcaac
    11581 agttaatgaa gcccttgatg cggcagctag cctgattgcg gaacttgcag gtgcgacggt
    11641 gcgtaagggc atcgtttcag cgggtgagct tgatacttca gatgtagaag tttcttcaac
    11701 ccttgctgat gttaatcgtg tcctcggaac tgagctgtct tatgctgatg tagaagacgt
    11761 cttccgtcgt cttggctttg gtctttctgg aaatgcagac agctttacag tcagagtccc
    11821 acgtcgtcgt tgggatatca caatcgaagc tgacctcttt gaagaaattg ctcgtatcta
    11881 tggttatgac cgcttgccaa ctagtctacc aaaagacgat ggtacagcag gtgaattgac
    11941 agccacacaa aaactccgcc gtcaagttcg tactattgct gaaggagcag gtttgacaga
    12001 aatcatcacc tatactctaa caactcctga aaaagcagtt gagtttacgg ctcaaccaag
    12061 taaccttacg gaactcatgt ggccaatgac tgtggatcgt tcagtcctcc gtcaaaatat
    12121 gatttcaggt atccttgata ccgttgccta caacgtggct cgtaagaata aaaacttggc
    12181 cctttacgag attggaaaag tctttgaaca aacaggtaat ccaaaagaag aacttccaaa
    12241 tgaaatcaac agttttgcct ttgccttgac aggcttggtt gctgaaaaag atttccaaac
    12301 agcagcagtt ccagttgatt tcttctatgc taagggaatc cttgaagccc tatttactcg
    12361 tttgggactc caagtaacct atacagcaac atctgaaatc gctagccttc atccaggtcg
    12421 tacagccgtg atttcattcg gtgaccaagt tcttggtttc cttggccaag tgcatccagt
    12481 cactgccaag gcttacgata ttccagaaac gtatgtggct gagcttaacc tttcagctat
    12541 cgaagctgcg cttcagccag cgactccatt tgtagaaatc accaaattcc cggcagtcag
    12601 ccgtgacgtt gcccttctcc tcaaggcaga agtgactcat caagaagttg tagatgctat
    12661 ccaagctgcc ggcgtgaaac gtttgacaga tatcaaactc tttgacgtct tctcaggtga
    12721 gaaattggga cttggtatga agtcaatggc ttatagcttg accttccaaa atccagaaga
    12781 tagcttaacg gacgaagaag tcgcacgcta tatggaaaaa atccaagcat cgctcgaaga
    12841 aaaagtcaat gcagaagtgc gttaaacgat agtatgatac aaattccccc tctagtttat
    12901 gaacactaga ggggtgattt tatataaaat aattaaaatg tgatttctgt aaaaatacat
    12961 ctatgatcag agttttgaaa acttacaatg tctaaatctt taacatagta gtggttttta
    13021 ggcaataaaa tatgatctat tgttgcatta aaaagttttg gactttggct attccaagtt
    13081 cctctttcaa aaggtggcag tacatttaat gcgtccctat gagagcttat ttttgcaagt
    13141 gctccatgac gcatagttgc attaaaatca cctgcaataa tagcctttgg atattttgaa
    13201 gccaattgat tatgaatgat gtttaagtct tgcttccaga tttccattaa acctggcaga
    13261 ggaggagcag tatgcaaggc aatgatatct ggtatatttt gttttctcga atgtaataca
    13321 attgtcccga accgtgttgt atgaaaagtt ttagcttctg tatagaaacc ataacttttc
    13381 ttgacaatca cagtcacagg agctattcca ctattggtag gtggagaagt gaaaatatca
    13441 tagttggcca tagaaagtcc aacttgatga aacaatagtt tgattctctg gttttcttgc
    13501 tcacctctga tattggtagc tagttcaggg aatatagcca tatcggcgtc aaaatggcta
    13561 aaaattcgct caatatgttg tgcttctatt tgattagcga cgttccaagt tactaatttt
    13621 aaggttttag tcttatttga tgcagaagaa agggttttat ctgttccgaa taatagtaat
    13681 atgagcgata gtaagagcaa aatgccagag taaaaccgta tttgtttatt tttcttgtaa
    13741 aaagataggg aaaaaaatac gaaacttaaa atagcagcca tagttgcagt agctaagggg
    13801 aaggcataaa tctgtgccaa gataggttgg gtagatagcc aaatgttaag attagaagat
    13861 gggaaaaaag aataagttat aatagggata gaaaagagaa tgaccgaaag ggcagagaga
    13921 aatgttttaa tcattgtgtg agtacctcaa tttgcaatgg ttgctcggag ctaatgtgac
    13981 tttgtgactt tacttgattg atattctttt tcttgtcttc ctcatagatt aagtacaacc
    14041 caagtaaaaa aagtccaatt taagattgaa atgattaaaa ggcacagaaa tgcaagacaa
    14101 ttatactaca aaaggcaaac atttgacaat cgatagccgt cgcttaatcg aacgatggaa
    14161 aaaagaagga aaatcaaata gagaaattgc ctctctactt ggaaaagctc ctcaaactat
    14221 ccatactgaa atcaagtatg ggacagtccg acaatgtctt ggaaaagggc gcttcaaaga
    14281 gatttattct gccgactacg ctcaacagtc ttatgaaaat aatcgcaagc actcggtcaa
    14341 gaaatcaagc ttgactaaga aactaaagga aaagattctc cactatcata accaaaaatt
    14401 ttcgcctgaa atgatggtga tggctaaagg ggttaacgtg ggaatttcaa ccatttacta
    14461 ttggattcat cgtggaaaat tggggttaag caagcaggat ctgctttatc ctagaaaagg
    14521 aaaagcgctt aagaaatagg ctagcaccaa ctttaaaccc gctggtcaat ctatcgaatc
    14581 ataattcgct cattttttta aaaatacata gacgtaaaaa aaagagggtt aagtgatgaa
    14641 gaatagtgct attgggagta attggaagga tgtccatctg agctctttag caaggaggaa
    14701 atccttgaaa gtgatatgcg agtggctatc atgagcgagt tgattgaggc taggtatgaa
    14761 caaggaatca gtcagaaaaa gctggaagaa gtcagtggaa taagccagcc tgtcatagct
    14821 aggatggaga caggagagag cagtcttcag ttggatacgg tcttaaaagt tctaaccagt
    14881 ctaggaaaga cactagcagt cgttccactt gaacagggga aaagttgact agaatcagtt
    14941 atagtctttt ctaataacag gtcatagtca cttataagaa ttactaataa catgttttag
    15001 tattctaatt ggaatatagc tgtaaagtaa gaattacaaa ggatttgaga cgtttgcttc
    15061 aagtcttttt cttttgtccg aaacagatat atagtttcaa actatatcaa accctaattt
    15121 tttacaatta tacagacgct ttcttttctg ttaagatagt ttcaacaaca aattttggag
    15181 gacacatcat gtcaactaca atcatcggtt tccctcgttt gggcgaattc cgtgaattaa
    15241 aatttacaac tgaaaaatac tttagaaaag aaatctcaga agaagaactt ttagcagcag
    15301 caaaagactt gcgtgctaaa cactggaaca ttgtcaaaga aaaaggcatc actgaaattc
    15361 catcaaatga cttttctcac tatgataact tcctagatgc ggctttcctt ttcaacgtgg
    15421 tgcctgcatc cgttcaaaac ttggacttgt ctgaccttga gcgctacttc gctttgggac
    15481 gtggttacca gggagaaaaa ggggacgttc gcgcccttcc aatgaagaaa tggttcaaca
    15541 ctaactacca ctacatcgtt cctaaatttg aaaaagacac tcaagtaaaa ttggctggtc
    15601 acaagatttt cgatgagttc caagaagcaa aagaacttgg attgaacact cgtcctgttc
    15661 ttgtaggtcc attcactttc cttcaattgt cagactttga agaaggcgtg aaagcagacg
    15721 acttcgtaga tagcttagtg gttgcttacc aagaagtttt tgctaaattg gctgaacttg
    15781 gtgcgactcg catccaattg gatgaagcgg ctcttgtaaa agacttgaca gctgaagaaa
    15841 aagctctctt cttgaacctt tacaacaaac tcttggctga caaaaaaggt cttgaagtct
    15901 tgcttcaaac ttatttcggt gatgttcgtg acgtatacgc tgaccttgta aacttgccag
    15961 tagatgctat cggtcttgac tttgttgaag gtaagaaaac tcttgaactc gttaaaggtg
    16021 gcttcccagc tgacaagact ctctatgtag gtattgtcaa tggtaaaaac atctggcgca
    16081 acaactacga aaagagcttg gctgttcttg agcaaatccc agctgaaaac atcgttttga
    16141 caagctcttg ctcacttctt catgtgccat ttacaactgc taatgaagaa tttgaaccag
    16201 cactcttgaa ccactttgcc tttgcagttg aaaaattgga tgaaatccgt gacttggatg
    16261 ctatccgcaa tggtcaaggt tcagaagctc ttgcagccaa caaagaactc tttgcgactg
    16321 agcgtgttgg tgaaaatgct gaacttcgtg cgcgtatcgc tggcttgaca gacgcagact
    16381 acactcgttt gccagccttt gcagaacgtg aagctatcca agaagaagct ttcaaacttc
    16441 cagctcttcc aacaacaacg attggttcat tccctcaaac aaaagaagtt cgtgccaaac
    16501 gtttggctta ccgtaaaggt gaattgtctc aaaaagagta cgatgctttc cttgctgaaa
    16561 cgattgacga atggatcaag tggcaagaag atattgactt tgatgtcctt gttcacggtg
    16621 aatttgagcg taatgacatg gttgagtact tcggtcaaaa cttgtcagga tacctcttct
    16681 ctaaaaatgg atgggtacaa tcatacggta tgcgtggggt aaaaccacca atcatctggg
    16741 gtgatgtcac tcgtcttaac tctatcactg ttaaatggtc tagctatgca caaagtcgta
    16801 caaacaaacc tgttaaaggt atgttgactg gacctgttac catccttaac tggtcattcc
    16861 cacgtgaaga catctctatc aaggattcaa ctcttcaaat cgcccttgct atcaaggatg
    16921 aagtacttga ccttgaagct gctggtgtga aaatcatcca aatcgacgag gctgctcttc
    16981 gtgaaaaatt gccactccgc cgtagcgact ggtacgaaga ctaccttgac tgggctattc
    17041 ctgccttccg cttggtacac tcaacagtag cgccagacac acaaatccac actcacatgt
    17101 gttactcaga atttacagat atcatcccag ctatcgataa catggatgca gacgttattt
    17161 cctttgaagc tagccgttca aaccttgaaa tcttggacga actcaaagcg aaaaacttcc
    17221 aaacagaagt gggacctggg gtttacgata tccactcacc tcgtgtacca aatgaaggcg
    17281 aaatcgacaa cacaatcgaa gccatccttg ctaaagtgcc aagcaagaaa gtttggatca
    17341 accctgactg tggtttgaaa acacgtggta tcccagaaac aaaagaaagc ttgatccgcc
    17401 ttgttgaagc agctaaagct gcgcgtgaga aattgtaaga ttggatttct ctccatacag
    17461 tggttgttca aaaagaaatc aactagaaaa ggttattaca tatgtcacgc caaacaccgt
    17521 cactctcatt tgaagtgttc cctccaaacc cagccgtggg taatggtaac attatttcag
    17581 ccttgcagga tatgcaggag ttggctcccc attttatcag tgtaactgcc agcaataata
    17641 aatttaatat caaggaaacg acggttcgtt tggctgactt tatccaaaat gacttggcga
    17701 ttccgaccat tgcccacttg ccagctattt atctaactaa ggacaaggtt gctgaaacta
    17761 ttgctgactt ggacaaagtt ggggtgcaga aaatcttggc tcttcgtggg gatattattc
    17821 cagacgtaga accacaaaag gatttccgct atgcaaccga cttgattgag tttatcaagg
    17881 aacaagcccc tcactttgat attattggag cttgctatcc agaagggcat ccagattcgc
    17941 caaatcagat ttcagatatt caaaatctta agaagaaagt ggatgcaggc tgttcgagcc
    18001 tcgtaactca gctcttcttt gataatgagc gcttctatga ttttcaggac aagtgtattt
    18061 tggctgggat tgatgttccc attcatgcag gaattatgcc aattctgaat cgaaatcagg
    18121 ctctccgact cttgaagact tgtgagaata tccatcttcc acgcaaattt aaagccatct
    18181 tagacaagta tgagcatgac cctgagtcgc tcagagcagc aggacttgcc tatgcagtgg
    18241 accaaatcgt ggacttggta actcaggatg ttgccggtgt gcatctctat acgatgaata
    18301 atgctgatac agcaaaatac atccatcaag caacccatgc cttgtttaat caccagtctc
    18361 taggataata aaagcaaacc attcttctca ggtgagggga atggttcctt tttaatggta
    18421 aagacctcac tttttaagaa aaatatgata aaataaattc tgtacgtact tgatacaaag
    18481 atgaaggtat taaataatac aatgcattta aactgtaaga tttaacgaca cgagtgagtc
    18541 aaatcgatgt tatttgacga gagagttagt aaagcattta gctaatcgcc cgatagcgat
    18601 tagcgtgaaa gctttagata ctttagtatt aaacctttct aatgatgtat cttgaaaact
    18661 gaacttgcct acaactctgt ggaaaaagat aaatctccct aggagcagtc gctccgtcgt
    18721 tcgatttcct attttccttt gagttgcttg acggcttggt atcttgatga cttgaatttt
    18781 ggtctcattt cttaggaaaa aagataagct tcctagcact cgtcgagtgc gacgtcacct
    18841 tcctattttt ctacagaaat gttcggcaag ccgaaccgtc caaaatatct tgtgtaattg
    18901 aacacggccg aaaagctgtg taaaaaagat aaactgtctt gtcttcatcg aagacttcgt
    18961 cagtttccta tttttacttt gcttttgacg tccttggtat cttgatcttt gtaggcaagg
    19021 cgtataattt catcaatcca aaggggatta aaatggcaaa acaagtgttt caaacgactt
    19081 ttgcgggtcg tgagttaatt gtagaaactg gtcaggttgc taagcaagca aatggctctg
    19141 ttgtcgtacg ttacggtgag tcaactgtct tgactgctgc cgttatgtct aagaaaatgg
    19201 caactgggga tttcttccca ctccaagtca actacgaaga aaaaatgtat gcggctggga
    19261 agtttcctgg tggctttatg aaacgtgaag gacgtccttc aacagatgcg accttgacag
    19321 cgcgtttgat tgaccgtccg attcgtccta tgtttgcgga aggtttccgt aatgaagtcc
    19381 aagtcatcaa tacagtgctt tcttatgatg aaaatgcatc tgcaccaatg gctgctatgt
    19441 ttggttcatc tttggcactg tctatttcag atattccatt tgacggacca attgctgggg
    19501 tacaagtggg atatgtagat ggccaaatca tcatcaaccc aagtcaagaa caagcagagc
    19561 aatctcttct tgaattgaca gtagctggaa ccaagcacgc tatcaacatg gtagagtctg
    19621 gtgccaaaga attgtcagaa gaaatcatgt tggaagcgct tcttaaaggg cacgaagctg
    19681 tcaaagaatt gattgccttc caagaagaaa tcgttgctgc tgtcggtaaa gaaaaagcag
    19741 aagtggaatt gcttcacgtg gatgctgaat tgcaagctga aatcattgca gcctacaaca
    19801 gtgacctcca aaaggcagtt caagtagaag agaaattggc ccgtgaagct gcaactcaag
    19861 cagtgaaaga ccaagtgact gccgtttacg aagaaaaata tgcgaaccac gaagaatttg
    19921 accgtattat gcgtgatgtg gctgaaatct tggaacaaat ggaacacgca gaagtgcgac
    19981 gtttaattac agaagacaag gtgcgtcctg atggtcgtaa ggtcgatgaa atccgtcctt
    20041 tggatgcggt tgttgacttc cttcctcgtg tacatggttc aggtctcttt actcgtgggc
    20101 aaactcaagc tctttcagtc ttgaccttgg ctccgatggg agaaactcaa atcattgatg
    20161 gtttggatcc agagtacaag aaacgcttta tgcaccacta taacttccct caatattctg
    20221 taggggaaac aggtcgttac ggtgcgccag gtcgtcgtga aatcggtcac ggtgcccttg
    20281 gtgagcgtgc tcttgctcaa gtcttgccaa gcttggaaga attcccatac gctatccgtc
    20341 tagtagcaga agttttggaa tcaaacggtt cttcatctca agcttctatc tgtgcgggaa
    20401 ctcttgccct tatgactggt ggtgtgccaa tcaaggcgcc agtagctggt attgctatgg
    20461 gacttatctc agatggaaat aactacacag tattgacaga tatccaaggt ttggaagatc
    20521 actttggaga tatggacttc aaggttgcag gtactcgtga tgggattaca gcccttcaaa
    20581 tggatatcaa gattcaaggg attactgcag aaatcttgac ggaggctctt gctcaagcca
    20641 agaaagcgcg ttttgaaatc cttgatgtca ttgaagcaac cattccagaa gttcgtccag
    20701 aattggctcc aactgctccg aaaattgata cgatcaagat tgatgtggac aagattaaga
    20761 ttgtcatcgg taagggtgga gaaaccatcg acaagattat cgctgaaaca ggtgttaaga
    20821 ttgatataga cgaagaagga aatgtgtcta tctactctag tgaccaagat gctattaacc
    20881 gtgccaaaga aattattgct ggtttggttc gtgaagccaa agtggatgaa gtttaccgtg
    20941 ctaaagtcgt tcgtatcgag aaatttggtg cctttgttaa cctctttgat aagacagatg
    21001 cccttgttca tatctctgag atggcttgga ctcgtaccaa tcgtgtagag gatttggtag
    21061 aaatcgggga tgaagttgat gttaaggtta tcaagattga tgaaaaaggc cgtatcgatg
    21121 cctctatgaa ggctcttcta cctcgtccgc caaaacctga gcatgatgaa aaaggtgaaa
    21181 agtctgagcg ccctcaccgc ccacgtcatc acaaggatca caaacctaag aaagaattta
    21241 cagaaacacc aaaagattca gagtaagaaa aggagaaatg tatggggtgg tggcacgaaa
    21301 ccattgatat cgtaaaagaa aatgatccag cggcccgcac cactttggag gttttgctga
    21361 cttatccagg tgtcaaggcc ttggcggccc accgtctctc gcattttctc tggaagtacg
    21421 acttcaaact cttagctcgt atgcacagtc agttttggcg cttttggact cagattgaga
    21481 ttcatccagg agcccagatt gattcaggtg tctttattga ccatggttct ggtctggtga
    21541 ttggagagac agcgattgtt gaaaaaggcg ttcttctcta tcacggagtg actctcgggg
    21601 gaacagggaa agactgtggc aaacgccatc cgactgtacg aaagggagcc ctcatatcag
    21661 cccatgccca agttatcggg cctgtggaaa ttggtgaaaa tgccaaggtc ggtgctgcag
    21721 cagttgtcgt agcagatgta cctagtgatg tgacggttgt cggtattccg gccaagattg
    21781 tccgtcttca tggtaagaaa gatgagcctg ttattcacga agtcgaagaa aaacgggagt
    21841 attatgtcaa taaactcgag caggctaaag atgccagtca cagatcgtct ggtttgtaga
    21901 ggatacctat atgattcaag caagaaacaa gttaagccaa gaggagctat ctgaggcgaa
    21961 aaaagtaatt aactgttgcc aaaactatga cggtacctat cgcgatccct atctctctaa
    22021 catgcttaat tttgacccaa acatgcccgc ctttttcctt tattatgaaa aaggcaaact
    22081 tgttggttta ttaactgtct atgcagatga ccaagatgta gaagtgacga tattggttca
    22141 tccaggtcat cgccgtcagg ggattgcgcg tgcattgttt actagttttg agagagaaac
    22201 agcttctttc cccattcggt cagtcacttt tcagacagaa cgtatttttt tagagaatca
    22261 tcctgacttt gccagtaact ggggactaat cgaggatgaa gagacagaaa cttggttagg
    22321 taaggataga agaccttatc cgttagcaaa tgtttcccat cttgaagttt tgttagcaga
    22381 tagttcgtat caggatcaaa ttagtcaatt aaaatttcag gcattttcag aggaacatga
    22441 atcgagagaa gttgtggata gatatgtcgc tgaagctctg aaggatccag aaagtcgctt
    22501 atatattttg ttaaaagacg gtcaggttat tgggacttgc acggtagatt tatcgactaa
    22561 tacgaattac ttctacggtt tagcaatatc ggaacctgaa cgtgggaaag gctatggaag
    22621 ctacttagca aaatccctcg tcaaccaact aattgagcaa aatgacaagg aatttcagat
    22681 tgcagtggaa gatagcaatg taggtgccaa acgtttgtat gaaaaaattg gctttgtcaa
    22741 acagacacag gtggtttatc tgaatgagaa aggagcaagg gattccgaag tgtagagaca
    22801 ttcggactga aatttacttg agctcttagt ttagtgatga aactaacagt tcttggattt
    22861 tagctttcct gattatgatt tatgattaaa atctatgaca ccatgtctcg tgatttgcga
    22921 gaatttgtcc cgattgagga cggcaagatc aagatgtatg tttgtgggcc aaccgtgtac
    22981 aactatattc acgtgggaaa cgcccgttcg acggtagctt ttgatacgat tcgtcgctat
    23041 tttgagtacc gtgggtataa ggttgcctat atttccaatt ttacagatgt ggatgataag
    23101 attatcaacc gtgccaggga agaaggcatc acacctcagg aggttgcgga taagtacatc
    23161 gctgcctttc gtgaggatgt gacggcctta ggcgtgaaac ctgcgactcg ccatccgcgt
    23221 gtagtggagt ttatggcaga catcatccgt tttgtggaag acttgatcga gaaaggcttt
    23281 gcctatgaga gtcaagggga tgtctatttc cgtgtagaaa aatcccacaa ctatgctaaa
    23341 ttggctaata aaaccttgga agatttggag ctaggtgctt caggtcgtac cgatgaagaa
    23401 acggctcgta aggaaaatcc tgtagacttt gctctatgga aatcttccaa accaggtgag
    23461 atttcttggg atagtccttg gggacctgga cgtccgggtt ggcatattga gtgttcagtc
    23521 atgtcgacag agattttagg tgataccatt gatatccacg gtggtggagc tgacctagag
    23581 tttccacacc acaccaatga aattgcccaa tctgaagcta aaacaggcaa ggcttttgct
    23641 aactactgga tgcacaatgg ctttgtcaat atcgacaatg tcaaaatgtc taagtccttg
    23701 ggtaacttca ttacggtaca cgatgccctt aaaactcttg atgggcaagt acttcgtttc
    23761 ttctttgcga cccagcacta ccgtaagcct atcaacttca cggaaaaggc agttcgcgat
    23821 gccgagacca atctcaagta tctgaagaat acttacgaac aaccatttac aggaaacgtg
    23881 gatgcccaag agttacaaaa ctttaaagat aagtttgtag cagctatgga tgaagatttt
    23941 aatgctgcca acggtatcac agttgtcttt gaaatggcca aatggatcaa ctcagggaac
    24001 tatgatgcaa gtgtcaagca agctcttgca gatatgttag aaatttttgg aattgtcttt
    24061 gttgaggaag ttttggatgc agagattgaa gacttgattc aaaaacgcca agaggcgcgt
    24121 gccaatcgtg actttgagac agcagaccaa atccgtgacc aattggttac tcaaggaatt
    24181 aagctccttg ataccaagga tggagtgagg tggacacgtg attgatgtca atctcattaa
    24241 cgggattgcg ctagcctttg agggagatgc ggtgtattct atgtatattc gccgccacct
    24301 catcctcaaa ggtatgacca agcccaataa actccaccaa gaggcgacca agtacgtgtc
    24361 agccaaggct caggctcgtc tgattgctct catgttggag gagcagatcc taacggaaaa
    24421 agaagaagaa atctacaaac gtggccgcaa taccaatagt cacacaaagg ctaaaaatgc
    24481 agatgtcgtg acttatcgta tgtccacggg atttgaagca gttatgggct atctccatat
    24541 gactgagaat ctggaacgtc ttgagagttt ggtttcatgg tgcatccaaa aagtggaggg
    24601 ctagaacatg agggcaaaag aactacaaga ctggtttcct gaggctcgga tttcagacca
    24661 accagtagag aaagagggct atctcacgct tcctttagct tctcagcagt ggattttgct
    24721 ggaggaagct gggctcagcg agcgtgaaaa gcagttggtt gcccttttga cccagcagga
    24781 gcaggctcgt tcgctaaacc cttggtattc ctatctggtt gagggcaagg gacaggcacc
    24841 gcaagttttt aaaaagattc agttggttta ttgccatctt tcttattttc agcaggaaaa
    24901 tctgacttct tggctagata tgatgcggac tctttttccg aattgtcaga cagtgctaca
    24961 ggtcggagct caggattatg ttttcgtgct tcaacaagac aaatacactt ctgtaagaga
    25021 tattttgagt gatacgattg aagcggttga gtatgacttt ggacttcgtc tttctatcat
    25081 gttgggtcag gtttggtctc agacaggaca tcaagcccta tcagacttaa tcaaagctga
    25141 gcgggatttg ttcaagacat ggtggcgtca gggtcaccaa ggtgttcata ctttttctca
    25201 gctctatctt tggagtatgg gagaaagact cgtggacttg aagccaatta aagaatgtct
    25261 acaccagatg attttggatc aagatcagat tcaggaaatc attctctctc tttgggaaaa
    25321 tagtgctgtt ctcactaaaa cagcccagca actctatctg caccgcaatt ctctccaata
    25381 caagattgat aaatgggaag agttgacagg gcttcagttg aaagagttga ccgacctgac
    25441 cttgtgttat caattgattt taggttcttt gtcaactata gttggtttgt aaagaagtta
    25501 ata
//
LOCUS       DBEJHE010000026        25132 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC4 isolate 671759
            SAMN38261586-rid24793303.denovo.26, whole genome shotgun sequence.
ACCESSION   DBEJHE010000026 DBEJHE010000000
VERSION     DBEJHE010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261586
            Sequence Read Archive: SRR26833752
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 25132)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25132)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576136.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576136.1
            Genome Coverage       :: 109x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 19:48:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,067
            CDSs (total)                      :: 2,029
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 131
            CDSs (without protein)            :: 131
            Pseudo Genes (ambiguous residues) :: 0 of 131
            Pseudo Genes (frameshifted)       :: 64 of 131
            Pseudo Genes (incomplete)         :: 59 of 131
            Pseudo Genes (internal stop)      :: 46 of 131
            Pseudo Genes (multiple problems)  :: 32 of 131
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25132
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261586-rid24793303.denovo.26"
                     /strain="GPSC4"
                     /isolate="671759"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            <1..333
                     /locus_tag="ACL3EZ_001500"
     CDS             <1..333
                     /locus_tag="ACL3EZ_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HGR0393049.1"
                     /translation="INVKETSDTANGSLSPSNSGSGVTPMNHNHATGTTDSMPADTMT
                     SSTNTMAGENMAASANKMSDTMMSEDKAMLPNTGETQTSMASIGFLGLALAGLLGGLG
                     LKNKKEEN"
     gene            500..1198
                     /locus_tag="ACL3EZ_001501"
     CDS             500..1198
                     /locus_tag="ACL3EZ_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000520636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGR0393050.1"
                     /translation="MGKTILLVDDEVEITDIHQRYLIQAGYQVLVAHDGLEALELFKK
                     KPIDLIITDVMMPRMDGYDLISEVQYLSPEQPFLFITAKTSEQDKIYGLSLGADDFIA
                     KPFSPRELVLRVHNILRRLHRGGETELISLGNLKMNHSSHEVQIGEEMLDLTVKSFEL
                     LWILASNPERVFSKTDLYEKIWKEDYVDDTNTLNVHIHALRQELAKYSSDQTPTIKTV
                     WGLGYKIEKPRGQT"
     gene            1195..2247
                     /locus_tag="ACL3EZ_001502"
     CDS             1195..2247
                     /locus_tag="ACL3EZ_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HGR0393051.1"
                     /translation="MKLKSYILVGYIISTLLTILVVFWAVQKMLIAKGEIYFLLGMTI
                     VASLVGAGISLFLLLPVFTSLGKLKEHAKRVAAKDFPSNLEVQGPVEFQQLGQTFNEM
                     SHDLQVSFDSLEESEREKGLMIAQLSHDIKTPITSIQATVEGILDGIIKESEQAHYLA
                     TIGRQTERLNKLVEELNFLTLNTARNQVETTSKDSIFLDKLLIECMSEFQFLIEQERR
                     DVHLQVIPESARIEGDYAKLSRILVNLVDNAFKYSAPGTKLEVVAKLEKDQLSISVTD
                     EGQGIAPEDLENIFKRLYRVETSRNMKTGGHGLGLAIARELAHQLGGEITVSSQYGLG
                     STFTLVLNLSGSENKA"
     gene            2442..3053
                     /gene="rpsD"
                     /locus_tag="ACL3EZ_001503"
     CDS             2442..3053
                     /gene="rpsD"
                     /locus_tag="ACL3EZ_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HGR0393052.1"
                     /translation="MSRYTGPSWKQARRLGLSLTGTGKELARRNYVPGQHGPNNRSKL
                     SEYGLQLAEKQKLRFTYGVGEKQFRNLFVQATKIKGGILGFNFMLLLERRLDNVVYRL
                     GLATTRRQARQFVNHGHILVDGKRVDIPSYRVTPGQVISVREKSLKVPAILEAVEATL
                     GRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML"
     gene            3239..3394
                     /locus_tag="ACL3EZ_001504"
                     /pseudo
     CDS             3239..3394
                     /locus_tag="ACL3EZ_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 transposase-related protein"
     gene            complement(3498..3635)
                     /locus_tag="ACL3EZ_001505"
                     /pseudo
     CDS             complement(3498..3635)
                     /locus_tag="ACL3EZ_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            3715..3975
                     /locus_tag="ACL3EZ_001506"
     CDS             3715..3975
                     /locus_tag="ACL3EZ_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0393053.1"
                     /translation="MTGVSNPTTDSARLVLAEAKKAFADDSLTEQGLRDILQTVKDAI
                     ASLESIKESQSATKDGGQTAGKETAGEDESANQTQEISQGIK"
     gene            3929..4150
                     /locus_tag="ACL3EZ_001507"
     CDS             3929..4150
                     /locus_tag="ACL3EZ_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0393054.1"
                     /translation="MSLQIKLKKLAKELSKLLKDSNLETVDKDVLENSQKELQKAVLF
                     LADEKGSEHTEAEVIDNLKEVIAKLKANA"
     gene            4469..5398
                     /locus_tag="ACL3EZ_001508"
     CDS             4469..5398
                     /locus_tag="ACL3EZ_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0393055.1"
                     /translation="MKKFSKTLRDNWIFLLMVLPGALWLILFFYIPVFGNVVAFKDYH
                     MTSNGFIDSIINSKWVGLDNFRFLFSSRDAFIITRNTVLYNLGFIFLGLVVSVGIAII
                     LSELRSKRMVKIFQTSMLFPYFLSWVIISFFTDAFLNIDKGVFNHLLESLGLKEVNFY
                     ADLGIWPYLLLFLGIWKGFGYSSVMYYATIMGIDPTYYEAATVDGASKWQRIRNVTIP
                     QLTPLVTVLTILAVGNIFRADFGLFYQIPHNAGQLYNVTNVLDVYVFNGLTQTADIGM
                     AAAAGLYQSVVGLILVILSNLLARRVDPNSALF"
     gene            5412..6335
                     /locus_tag="ACL3EZ_001509"
     CDS             5412..6335
                     /locus_tag="ACL3EZ_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001075101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGR0393056.1"
                     /translation="MAKKKIKKEKIDNVGIHSFSKKADIFFSIISGLIALSCILPFVF
                     VIIISVTDEKSLLQYGYSFFPSQFGLDGFEFLAQFKDKILQALFISVFVTVVGTLTNV
                     FITTTYAYAISRTTFKYRRFFTIFVLLSMLFNAGLVPGYIMVTRVLQLGDTVWALIVP
                     MLLSPFNIILMRSFFKKTIPEAILESARIDGASEARIFFQICLPLSLPGIATITLLTA
                     LGFWNDWFNALLYIKSDNLYPLQYLLMQIQQNMDYIAKAVGLTGQLGVALPKETGRMA
                     MVVVATLPIAILYPFFQRYFVKGLTIGGVKE"
     gene            6593..8068
                     /locus_tag="ACL3EZ_001510"
     CDS             6593..8068
                     /locus_tag="ACL3EZ_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGR0393057.1"
                     /translation="MKNWKKYAFASASVVALAAGLAACGNLTGNSKKAADSGDKPVIK
                     MYQIGDKPDNLDELLANANKIIEEKVGAKLDIQYLGWGDYGKKMSVITSSGENYDIAF
                     ADNYIVNAQKGAYADLTELYKKEGKDLYKALDPAYIKGNTVNGKIYAVPVAANVASSQ
                     NFAFNGTLLAKYGIDISGVTSYETLEPVLKQIKEKAPDVVPFAIGKVFIPSDNFDYPV
                     ANGLPFVIDLEGDTTKVVNRYEVPRFKEHLKTLHKFYEAGYIPKDVATSDTSFDLQQD
                     TWFVREETVGPADYGNSLLSRVANKDIQIKPITNFIKKNQTTQVANFVISNNSKNKEK
                     SMEILNLLNTNPELLNGLVYGPEGKNWEKIEGKENRVRVLDGYKGNTHMGGWNTGNNW
                     ILYINENVTDQQIENSKKELAEAKESPALGFIFNTDNVKSEISAIANTMQQFDTAINT
                     GTVDPDKAIPELMEKLKSEGAYEKVLNEMQKQYDEFLKNKK"
     gene            8340..9326
                     /locus_tag="ACL3EZ_001511"
     CDS             8340..9326
                     /locus_tag="ACL3EZ_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HGR0393058.1"
                     /translation="MAKDIRVLLYYLYTPIENAEQFAADHLAFCKSIGLKGRILVADE
                     GINGTVSGDYETTQKYMDYVHSLPGMEDLWFKIDEESEQAFKKMFVRYKKEIVHLGLE
                     DNDFDNDINPLETTGAYLSPKEFKEALLDKDTVVLDTRNDYEYDLGHFRGAIRPDIRN
                     FRELPQWVRDNKEKFMDKRVVVYCTGGVRCEKFSGWMVREGYKDVGQLHGGIATYGKD
                     PEVQGELWDGKMYVFDERIAVDVNHVNPTIVGKDWFDGTPCERYVNCGNPFCNRRILT
                     SEENEDKYLRGCSHECRVHPRNRYVSKNELTQAEVIERLAAIGESLDQAATV"
     gene            9601..10461
                     /locus_tag="ACL3EZ_001512"
     CDS             9601..10461
                     /locus_tag="ACL3EZ_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4299 family protein"
                     /protein_id="HGR0393059.1"
                     /translation="MAKTFFIPNKQSILGEQEILNAKSILALLDGLESHSYDVVYLRQ
                     PLNRLEYIECAIVGQSQFLFKVSYADGQKAYRVDLPDLLTKTDWQIIKSFLDALLAYT
                     GTDIEGLDGFDFEAYFQASIQAYLADPVARFTICQGIFNPIFFSRENLKSFLEADGLA
                     QFEARVRAVQETDAYFARVSFYQDGEGKVHGVYHLAQGVKTVLPREPFVPAAYIEQLV
                     DKEVQWEIDLVQITGDGSKPEDYESIARLDYAKFLEVLPPSFYHQLDANQIEVQPILD
                     KDFKTLAQEK"
     gene            10847..11011
                     /locus_tag="ACL3EZ_001513"
     CDS             10847..11011
                     /locus_tag="ACL3EZ_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0393060.1"
                     /translation="MDESKYLCYLEKYDALGSGRLLAKVNNTYYMFNKNQIELLRYSN
                     KNAKKERKYM"
     gene            11137..11898
                     /locus_tag="ACL3EZ_001514"
     CDS             11137..11898
                     /locus_tag="ACL3EZ_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001823689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0393061.1"
                     /translation="MTRFYIPQKLNDYIGQKKSKFIPFLPNPVLITKVMLYCSPILAL
                     FLCYACYDIQLNISKVPRNIITFLVGSVVAIIHELLIMIYYLKSGRVPGRIYIRIVYL
                     VVISFGTEWGASYSEKKVFRTTMFLFSMISIFYLSAIFFMIFYLLQYLKLYTAAYYTS
                     IYAVGTLIFAFINAYPFLLKTDGYILYQEFFGIYKIRSLFFKTLFYCIGIRNNLKLQE
                     VVKRNNLKTYIWDLFFIISIIGLLYILYSSIRFII"
     gene            12297..12422
                     /locus_tag="ACL3EZ_001515"
     CDS             12297..12422
                     /locus_tag="ACL3EZ_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000164657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0393062.1"
                     /translation="MTKNINFTLFDKENYESNNLDSLNLNIALSHQIDGKATNIS"
     gene            12447..12644
                     /locus_tag="ACL3EZ_001516"
     CDS             12447..12644
                     /locus_tag="ACL3EZ_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001257240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="macrolide ABC transporter ATP-binding protein"
                     /protein_id="HGR0393063.1"
                     /translation="MRSLSQEKDIYSFDEPTGNLDRNSTELFLNEVEKLVNEEKIVIV
                     VTHDKDVIARASKVINMDEFH"
     gene            complement(12881..13945)
                     /locus_tag="ACL3EZ_001517"
     CDS             complement(12881..13945)
                     /locus_tag="ACL3EZ_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6574 domain-containing protein"
                     /protein_id="HGR0393064.1"
                     /translation="MKQEWFESNDFVKTTSKNKPEEQAQEVADKAEETIADLDTPIGK
                     NTQVEEEVSQAEVELESQQEEKIETPEGGEARTEIEEKKASNSTEEEPDLSKETEKVT
                     IAEESQEALPQQKATTKEPLLISKSLESPYIPDQAPKSRDKWKEQVLDFWSWLVEAIK
                     SPTSKLETSITHSYTAFLLLILFSASSFFFSIYHIKHAYYGHIASINSRFPEQLAPLT
                     LFSIISILVATTLFFFSFLLGSFVVRRFIHQEKDWTLDKVLQQYSQLLAIPIFLTAIA
                     SFFAFFDSLRFTALLCVISIGIILLASLHIITRPSQASETDSFYQLFLSVLVNGVIIL
                     LFFVAEVALIGDYLRILAFL"
     gene            complement(14008..14919)
                     /locus_tag="ACL3EZ_001518"
     CDS             complement(14008..14919)
                     /locus_tag="ACL3EZ_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001233690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 domain-containing protein"
                     /protein_id="HGR0393065.1"
                     /translation="MRKWTKGFLIFGVVTTVIGFILLFVGIQSDGIKSLLSMSKEPVY
                     DSRTEKLTFGKEVENLEITLHQHTLTITDSFDDQIHISYHPSLSAHHDLITNQNDRTL
                     SLTDKKLSETPFLSSGIGGILHIASSYSSRFEEVILRLPKGRTLKGINISANRGQTTI
                     INASLENATLNTNSYILRIEGSRIKNSKLTTPNIVNIFDTVLTDSQLESTENHFHAEN
                     IQVHGKVELTAEDYLRIILDQKESQRINWDISSNYGSIFQFTREKPESRGTELSNPYK
                     TEKTDVKDQLIARSDDNIDLISTPSRR"
     gene            complement(14912..15505)
                     /locus_tag="ACL3EZ_001519"
     CDS             complement(14912..15505)
                     /locus_tag="ACL3EZ_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000198695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HGR0393066.1"
                     /translation="MTRTEYLTQLELYLKKLPEADRIEAMDYFRELFDDAGVEGEEEL
                     IASLGTPKEVAHEVLSNLLDKKINEAPAQKNNRQILHIALLALLAAPIGIPLGIAILV
                     TLFAILVAALTVILAFFAVSILGIIGGFLFLVESFTVLAQAKSAFILIFGSGLLAIGA
                     SSLVLLGISYVARFFGLLIVRLVQFVLKKGKRGNQHA"
     gene            complement(15492..15818)
                     /locus_tag="ACL3EZ_001520"
     CDS             complement(15492..15818)
                     /locus_tag="ACL3EZ_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HGR0393067.1"
                     /translation="MYFPTSSALIEFLILAVLEQGDSYGYEISQTIKLIANIKESTLY
                     PILKKLEGNSFLTTYSREFQGRMRKYYSLTNGGIEQLLTLKDEWTLYTDTINGIIEGS
                     IRHDKN"
     gene            complement(15957..17123)
                     /locus_tag="ACL3EZ_001521"
     CDS             complement(15957..17123)
                     /locus_tag="ACL3EZ_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CynX/NimT family MFS transporter"
                     /protein_id="HGR0393068.1"
                     /translation="MKKQSLFFVPGIILIGVSLRTPFTVLPIILGNISQGLEVEVSSL
                     GVLTSLPLLMFTLFSPFSTQLAQKIGLEHLFTYSLFFLTIGSLIRLINLPLLYLGTLM
                     VGASVAVINVLLPSLIQANQPKKIGFLTTLYVTSMGIATALASYLAVPITQASSWKGL
                     ILLLTLLCLATFLVWLPNHRYNHRLAPQTKQKSQIKVMRNKQVWAIIIFSGFQSLIFY
                     TAMTWLPTMSIHAGLSSHEAGLLTSILSLISIPFSMTIPSLTTSLSTRNRQLMLTLVS
                     LAGVVGISMLFFPINNFIYWLAIHLLIGTATSALFPYLMVNFSLKTSAPEKTAQLSGL
                     SQTGGYILAAFGPTLFGYSFDLFHSWVPAVAALLLIDILMTVALFTVDRADKIL"
     gene            17181..18338
                     /locus_tag="ACL3EZ_001522"
     CDS             17181..18338
                     /locus_tag="ACL3EZ_001522"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HGR0393069.1"
                     /translation="MSSKVSGFQDKNGKVLKIMIEWWKEKFRRVVVTQNVESLLVSIV
                     ISAYNEEKYLPGLIEDLKNQTYPKENIEILFINAMSTDGTTAIIQQFIKEDTEFNSIR
                     LYNNPKKNQASGFNLGVKHSVGDLILKIDAHSKVTETFVMNNVAIIQQGEFVCGGPRP
                     TIVEGKGKWAETLHLVEENMFGSSIANYRNSSEDRYVSSIFHGMYKREVFQKVGLVNE
                     QLGRTEDNDIHYRIREHGYKIRYSPSILSYQYIRPTFKKMLHQKYSNGLWIGLTSHVQ
                     FKCLSLFHYVPCLFVLSLVFSLALLPITFVFITLLLGAYFLLLSLLTLLTLLKHKNGF
                     LIVMPFLLFSIHFAYGLGTIVGLIRGFKWKKEYKRTIIYLDKISQINKNML"
     gene            18380..20230
                     /locus_tag="ACL3EZ_001523"
     CDS             18380..20230
                     /locus_tag="ACL3EZ_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HGR0393070.1"
                     /translation="MNKKLTDYVIDLVEILNKQQKQVFWGIFDIFSMVVSIIVSYILF
                     YGLINPAPVDYIIYTSLAFLFYQLMIGFWGLNASISRYSKITDFMKIFFGVTASSVLS
                     YSICYAFLPLFSIRFIILFILLSTFLILLPRITWQLIYSRRKKGSGDGEHRRTFLIGA
                     GDGGALFMDSYQHPTSELELVGILDKDSKKKGQKLGGIPVLGSYDNLPELAKRHQIER
                     VIVAIPSLDPSEYERILQMCNKLGVKCYKMPKVETVVQGLHQAGTGFQKIDITDLLGR
                     QEIRLDESRLGAELTGKTILVTGAGGSIGSEICRQVSRFNPERIVLLGHGENSIYLVY
                     HELIRKFQGIDYVPVIADIQDYDRLLQVFEQYKPAIVYHAAAHKHVPMMERNPKEAFK
                     NNIRGTYNVAKAVDEAKVSKMVMISTDKAVNPPNVMGATKRVAELIVTGFNQRSQSTY
                     CAVRFGNVLGSRGSVIPVFERQIAEGGPVTVTDFRMTRYFMTIPEASRLVIHAGAYAK
                     DGEVFILDMGKPVKIYDLAKKMVLLSGHTESEIPIVEVGIRPGEKLYEELLVSTELVD
                     NQVMDKIFVGKVNVMPLESINQKIGEFRTLSGDELKQAIIAFANQTTHIE"
     gene            complement(20316..20528)
                     /locus_tag="ACL3EZ_001524"
     CDS             complement(20316..20528)
                     /locus_tag="ACL3EZ_001524"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0393071.1"
                     /translation="MKIKEQTRKLAAGCSKHCFEVADRTDEVSSKHCFKVVDGTDEVS
                     SKHCFEVVDRTDEVSNHLRQGDVDVV"
     gene            complement(20578..21210)
                     /locus_tag="ACL3EZ_001525"
     CDS             complement(20578..21210)
                     /locus_tag="ACL3EZ_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HGR0393072.1"
                     /translation="MTSITAIFFDLDGTLVDSSIGIHNAFTYTFKELGVPSPDAKTIR
                     GFMGPPLESSFATCLSKDQISEAVQIYRSYYKAKGIYEAQLFPQIIDLLEELSSSYPL
                     YITTTKDTSTAQDMAKNLEIHHFFDGIYGSSPEAPHKADVIHQALQTHQLAPEQAIII
                     GDTKFDMLGARETGIQKLAITWGFGEQADLLNYQPDYIAHKPLEVLAYFQ"
     gene            complement(21232..22104)
                     /gene="sdaAA"
                     /locus_tag="ACL3EZ_001526"
     CDS             complement(21232..22104)
                     /gene="sdaAA"
                     /locus_tag="ACL3EZ_001526"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003941 - L-serine ammonia-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA];
                     GO_process: GO:0006565 - L-serine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HGR0393073.1"
                     /translation="MFYSIKELVEQADLDFQGNVAELMITTEFELTGREREEVFLLME
                     RNLEVMKASVQLGLNENKSRSGLTGGDAAKLDHYIKNEKTLSDYTILSAARNAIAVNE
                     HNAKMGLVCATPTAGSAGCLPSVLTAAIEKLDLSHEQQLDFLFAAGAFGLVIANNASI
                     SGAEGGCQAEVGSASAMSAAALTLAAGGTPYQASQAIAFVIKNMLGLICDPVAGLVEV
                     PCVKRNAMGASFAFIAADMALAGIESKIPVDEVIDAMYQVGASMPTAFRETAEGGLAT
                     TPTGRRLQKEIFGE"
     gene            complement(22113..22784)
                     /gene="sdaAB"
                     /locus_tag="ACL3EZ_001527"
     CDS             complement(22113..22784)
                     /gene="sdaAB"
                     /locus_tag="ACL3EZ_001527"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003941 - L-serine ammonia-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA];
                     GO_process: GO:0006565 - L-serine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HGR0393074.1"
                     /translation="MKSLRFQSVFDIIGPVMIGPSSSHTAGAVRIGKIVSSIFDDTPT
                     EVEFQLFNSFAKTYRGHGTDLALVAGILGMDTDDPEIPNSLEIAHKRGIKIVWTIQKD
                     SNAPHPNTTKITVKNAHKTISVTGISIGGGNIQVTELNGFAVSLNMNTPTIIIVHQDI
                     PGMIALVTEALSRYGINIAQMNVTREKAGEKAIMIIEVDSRNCDEAIEEIRKIPHLHN
                     VNFFK"
     gene            23026..23598
                     /locus_tag="ACL3EZ_001528"
     CDS             23026..23598
                     /locus_tag="ACL3EZ_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HGR0393075.1"
                     /translation="MKSITKKIKATLAGVAALFAVFAPSFVSAQESSTYTVKEGDTLS
                     EIAETHNTTVEKLAENNHIDNIHLIYVDQELVIDGPVAPVATPAPATYAAPAAQDETV
                     SAPVVSETVVSTVSGSEAEAKEWIAQKESGGSYTATNGRYIGRYQLTDSYLNGDYSAE
                     NQERVADAYVAGRYGSWTAAKNFWLNNGWY"
     gene            complement(23651..23971)
                     /locus_tag="ACL3EZ_001529"
     CDS             complement(23651..23971)
                     /locus_tag="ACL3EZ_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HGR0393076.1"
                     /translation="MQRLEVYKNYQHLYDLRMTILLNLSTLYLYNQDKNMCKQICYTL
                     LEDAKNKKSYDRLAICYVRIGICRDDAKLIQKGFSLLELTEETSMLSHLKKEVETHYQ
                     PKKL"
     gene            24735..25088
                     /locus_tag="ACL3EZ_001530"
     CDS             24735..25088
                     /locus_tag="ACL3EZ_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HGR0393077.1"
                     /translation="MELVLPNNYVVIDEEEMMYLGGGAYLSKRACQGICAALAMSPGT
                     FIALAGAAVLTKKLINYIKVGGLGGWLIGAAAGVLAGAAGRIAYCIGYGALNRGCDIN
                     GNPYPWDGFISATVR"
BASE COUNT         7739 a         4488 c         5275 g         7630 t
ORIGIN      
        1 ataaatgtta aagaaacatc agacacagca aatggttcat tatcaccttc taactctggt
       61 tctggcgtga ctccgatgaa tcacaatcat gctacaggta ctacagatag catgcctgct
      121 gacaccatga caagttctac caacacgatg gcaggtgaaa acatggctgc ttctgctaac
      181 aagatgtctg atacgatgat gtcagaggat aaagctatgc taccaaatac tggtgagact
      241 caaacatcaa tggcaagtat tggtttcctt gggcttgcgc ttgcaggttt actcggtggt
      301 ctaggtttga aaaacaaaaa agaagaaaac taatcagcta aggaaataaa tgatggatag
      361 tgggctgact aagattagtt taacaactca atcagcaatc aggactttct ttcaatagca
      421 gattaaaatc atcgtaaaac aataaaaata gtgttatact taaagcagta tagcactgtt
      481 tttatcaaag gagagacaga tgggaaagac aattttactc gttgacgacg aggtagaaat
      541 cacagatatt catcagagat acttaattca ggcaggttat caggtcttgg tagcccatga
      601 tggactggaa gcgctagagc tgttcaagaa aaaaccgatt gatttgatta tcacagatgt
      661 catgatgcct cggatggatg gttatgattt aatcagtgag gttcaatact tatcaccaga
      721 gcagcctttc ctatttatta ctgctaagac cagtgaacag gacaagattt acggcctgag
      781 cttgggagca gatgatttta ttgctaagcc ttttagccca cgtgagctgg ttttgcgtgt
      841 ccacaatatt ttgcgccgcc ttcatcgtgg gggcgaaaca gagctgattt cccttggcaa
      901 tctaaaaatg aatcatagta gtcatgaagt tcaaatagga gaagaaatgc tggatttaac
      961 tgttaaatca tttgaattgc tgtggatttt agctagcaat ccagagcgag ttttctccaa
     1021 gacagacctc tatgaaaaga tctggaaaga agactacgtg gatgacacca ataccttgaa
     1081 tgtgcatatc catgctcttc gacaggagct ggcaaaatat agtagtgacc aaacgcccac
     1141 tattaagaca gtttgggggt tgggatataa gatagagaaa ccgagaggac aaacatgaaa
     1201 ctaaaaagtt atattttggt tggatatatt atttcaaccc tcttaaccat tttggttgtt
     1261 ttttgggctg ttcaaaaaat gctgattgcg aaaggcgaga tttacttttt gcttgggatg
     1321 accatcgttg ccagccttgt cggtgctggg attagtctct ttctcctatt gccagtcttt
     1381 acgtcgttgg gcaaactcaa ggagcatgcc aagcgggtag cggccaagga ttttccttca
     1441 aatttggagg ttcaaggtcc tgtagaattt cagcaattag ggcaaacttt taatgagatg
     1501 tcccatgatt tgcaggtaag ctttgattcc ttggaagaaa gcgaacgaga aaagggcttg
     1561 atgattgccc agttgtcgca tgatattaag actcctatca cttcgatcca agcgacggta
     1621 gaagggattt tggatgggat tatcaaggag tcggagcaag ctcattatct agcaaccatt
     1681 ggacgccaga cggagaggct caataaactg gttgaggagt tgaatttttt gaccctaaac
     1741 acagctagga atcaggtgga aactaccagt aaagacagta tttttctgga caagctctta
     1801 attgagtgca tgagtgaatt tcagtttttg attgagcagg agagaagaga tgtccacttg
     1861 caggtaatcc cagagtctgc ccggattgag ggagattatg ctaagctttc tcgtatcttg
     1921 gtgaatctgg tcgataacgc ttttaaatat tctgctccag gaaccaagct ggaagtggtg
     1981 gctaagctgg agaaggacca gctttcaatc agtgtgaccg atgaagggca gggtattgcc
     2041 ccagaggatt tggaaaatat tttcaaacgt ctttatcgtg tcgaaacttc gcgtaacatg
     2101 aagacaggtg gtcatggatt aggacttgcg attgcgcgtg aattggccca tcaattgggt
     2161 ggggaaatca cagtcagcag ccagtacggt ctaggaagta cctttaccct cgttctcaac
     2221 ctctctggta gtgaaaataa agcctaaaac ccctttacaa atccagctat tcatggtaga
     2281 atagattttg tgtgaaatat cagcaggaaa gcatgaagct cgtcaacagg tgtcttatga
     2341 caagtaacct tggctgttta ggcgaagggc atctgcacga atcagggctt tctaagtgac
     2401 tatttccacc gaaatattat ttatatcagg aggacattca tatgtcacgt tatacaggac
     2461 catcttggaa acaagctcgt cgccttggcc tttcacttac aggtacaggt aaagaattgg
     2521 cacgtcgtaa ctacgtacca ggacaacacg gaccaaacaa ccgttctaaa ttgtcagaat
     2581 acggtttgca attggctgaa aaacaaaaac ttcgtttcac ttacggtgta ggtgaaaaac
     2641 aattccgtaa cttgttcgta caagctacaa aaatcaaagg cggaatccta ggtttcaact
     2701 ttatgcttct tttggaacgt cgtttggata acgttgttta ccgtcttggt ctcgcgacta
     2761 ctcgtcgtca agctcgtcaa ttcgtaaacc acggtcacat ccttgttgac gggaaacgcg
     2821 ttgatatccc atcataccgt gtaactccag gtcaagtgat ctcagttcgt gaaaaatcat
     2881 tgaaagttcc agcaatcctt gaagcagtag aagctactct tggacgtcca gcattcgtat
     2941 cattcgacgc tgaaaagttg gaaggttcat tgactcgctt gccagaacgc gacgaaatca
     3001 acccagaaat caacgaagca cttgtcgttg aattctacaa caaaatgttg taatatttta
     3061 ttgaataaga tagactttga ggccttgata ttaagcactt tgggacgttc tcccttagtg
     3121 cttttttgat ttctcttagt atccagctat aatcgttgag acataactag accgatatag
     3181 tccaaagtga tatagtaaaa tgaaccaaaa atagtacaca atgtggtata atccttttat
     3241 ggcatattca atagattttc gtaaaaaagt tctctcttat tgtgagcgaa caggtagtat
     3301 aacagaagca tcacacgttt tccaaatctc acgtaatacc atttatggct ggttaaagct
     3361 aaaagagaaa acaggagagc taaaccacca agtatagtgt attgaatcta taacagtaca
     3421 ccttggctgc taaaatattt ctataaatta atttgacttt cctgatagag atgttcacat
     3481 cttatttcaa actactataa aagttctata atctctttat aagatttgcc catcagacaa
     3541 aatagaacga tttgaaggcg tttatgatat ttagctgtac gagagtcttt taaaagtgtt
     3601 ttgatggttt ggatttcttc tttagttgat ttcatatcac tgttatataa tactttttga
     3661 ttttagtcta gtattagtaa gcagactcaa accttagaaa atcttttgag atcattgaca
     3721 ggtgtatcga atcctaccac agattcagca cgtctggttt tggcagaggc taagaaagct
     3781 tttgcagatg atagtttgac agagcaaggt ttacgtgata tcttgcaaac agtcaaagat
     3841 gccattgctt ccctagagtc cattaaggaa agccagtcag caactaagga tggaggacaa
     3901 acagcgggca aagaaacagc aggagaagat gagtctgcaa atcaaactca agaaattagc
     3961 caaggaatta agtaaacttc ttaaagactc aaaccttgaa acagtagata aggatgtcct
     4021 tgaaaactct caaaaagaac ttcaaaaagc agttttgttc ttggcagatg aaaaaggctc
     4081 tgagcatact gaagcagagg tgattgataa tcttaaagag gttattgcta agttgaaagc
     4141 aaacgcctaa taacatatta aaaatctcca gattaggaac tatctctgag ttccctagtc
     4201 tggagatttt tcagtatacc ccgttgttgg atgcttataa cagagtgacg ccatcactgg
     4261 gctaatagag ataaaataaa caattgattt aggacatttg tttgatagtg gtgataaagt
     4321 tttaaatctg ctacataatt tgtggagttt tttctataat taggagttta acctaacctg
     4381 caaataggag tatactaata atgtaatcgt tatcaaaagt ctaaaaaaga atttttagat
     4441 ggatatcaaa ataaaaaggg aggaaattat gaaaaagttt tcaaaaacat tgagagacaa
     4501 ctggatcttt ctcttgatgg ttttgccagg ggcactctgg ttgattctat tcttttacat
     4561 tccagtattt gggaacgtgg ttgccttcaa agactaccac atgaccagta atggtttcat
     4621 agatagtatc ataaatagta aatgggtcgg actcgataat ttcagattct tatttagttc
     4681 aagagacgcc tttattatca cacgaaatac tgtcctctac aatcttggct ttatctttct
     4741 aggtttagtt gtatctgtag ggattgccat tatcctcagc gagctccgtt ctaagagaat
     4801 ggtgaagatt ttccaaactt ctatgttgtt cccttacttc ttgtcttggg ttatcatcag
     4861 tttctttaca gatgccttcc taaatattga taaaggggtg ttcaatcatc tattggaaag
     4921 tcttggtctc aaagaagtca atttctacgc tgacctgggc atctggccct atctcctact
     4981 tttcctaggt atttggaaag gttttggata tagcagtgtc atgtactatg cgacgatcat
     5041 gggaattgat ccaacctact acgaagcagc gacagtggac ggagctagca agtggcaacg
     5101 tattcgcaac gtaaccattc ctcagttgac tccgcttgta actgtattga ccatccttgc
     5161 agtcggaaat atcttccgcg cagacttcgg tctcttctat caaatcccac acaatgctgg
     5221 tcagctttac aatgtaacca acgttttgga cgtatatgtt tttaatggtt tgactcagac
     5281 agcagatatc ggtatggctg cagcagccgg tctttaccaa tccgttgttg gtttgattct
     5341 ggttatccta tcaaacttgc ttgcaagacg agtcgatcca aactcagctt tgttctagaa
     5401 aggaggagaa tatggcaaaa aagaaaatta aaaaagaaaa aattgataat gtcggcattc
     5461 actccttcag taagaaagca gatatcttct tcagtatcat ttcgggtttg attgccctct
     5521 cttgtatcct accttttgta ttcgttatca ttatttcagt gacagacgag aaaagcctcc
     5581 tccaatacgg ctatagcttc ttcccatccc aatttggctt agacggtttt gagtttttgg
     5641 cacagtttaa ggataaaatc ctacaagccc tcttcatctc tgtctttgta accgtagttg
     5701 ggacattgac aaatgtcttt atcacaacaa cctatgccta cgctatttca cggacaacct
     5761 ttaagtatcg cagatttttt accatcttcg tccttctcag tatgttgttc aacgctggtt
     5821 tggtaccagg ttatatcatg gtgacccgtg tacttcagct tggtgacact gtttgggcct
     5881 tgattgttcc aatgcttctc tcaccattca atatcatctt gatgcgttcc ttcttcaaga
     5941 agaccattcc agaagccatt ctcgaatcgg ctcgtatcga tggtgccagt gaggcccgga
     6001 ttttcttcca aatctgtttg ccattgtcac taccaggtat cgcaaccatc acgcttttga
     6061 cagctcttgg tttctggaat gactggttca acgcccttct ttacatcaag agtgataact
     6121 tgtatccatt gcaatatttg ctcatgcaaa tccaacaaaa tatggactac attgccaaag
     6181 cggtcggctt gactggtcaa ctgggagttg ctctaccgaa agaaacaggt cgtatggcca
     6241 tggttgtggt tgcaaccctt ccaatcgcga ttttatatcc attcttccaa cgctactttg
     6301 taaaaggttt gactatcggt ggtgtgaaag aatagtgctt attgaaaaag aacatttctc
     6361 agttcccaac ttcccttgtg tgaagttaat actcttcgaa aatcaaattc aaaccgcgtc
     6421 aacgtcgcct tgccgtagat atatgtaact gacttcgtca gtcttatcta caacctcaaa
     6481 gcagtgcttt gagcagcctg cggctagttt tctagtttgc tctttgattt tcattgagta
     6541 taagatcatt acattgttta taagtttaaa aataaaaaaa ggagttttta tcatgaaaaa
     6601 ctggaaaaaa tatgcttttg catctgctag tgtagtcgct ttggctgcag gtcttgctgc
     6661 ttgtggaaat ttgacaggta acagcaaaaa agctgctgat tcaggtgaca aacctgttat
     6721 caaaatgtac caaatcggtg acaaaccaga caacttggat gaattgttag caaatgccaa
     6781 caaaatcatt gaagaaaaag ttggtgccaa attggatatc caataccttg gctggggtga
     6841 ctatggtaag aaaatgtcag ttatcacatc atctggtgaa aactatgata ttgcctttgc
     6901 agataactat attgtaaatg ctcaaaaagg tgcttacgct gacttgacag aattgtacaa
     6961 aaaagaaggt aaagaccttt acaaagcact tgacccagct tacatcaagg gtaatactgt
     7021 aaatggtaag atttacgctg ttccagttgc agccaacgtt gcatcatctc aaaactttgc
     7081 cttcaacgga actctccttg ctaaatatgg tatcgatatt tcaggtgtta cttcttacga
     7141 aactcttgag ccagtcttga aacaaattaa agaaaaagct ccagacgtag taccatttgc
     7201 tattggtaaa gttttcatcc catctgataa ctttgactac ccagtagcaa acggtcttcc
     7261 attcgttatc gaccttgaag gcgatactac taaagttgta aaccgttacg aagtgcctcg
     7321 tttcaaagaa cacttgaaga ctcttcacaa attctatgaa gctggctaca ttccaaaaga
     7381 cgtcgcaaca agcgatactt cctttgacct tcaacaagat acttggttcg ttcgtgaaga
     7441 aacagtagga ccagctgact acggtaacag cttgctttca cgtgttgcca acaaagatat
     7501 ccaaatcaaa ccaattacta acttcatcaa gaaaaaccaa acaacacaag ttgctaactt
     7561 tgtcatctca aacaactcta agaacaaaga aaaatcaatg gaaatcttga acctcttgaa
     7621 tacgaatcca gaactcttga acggtcttgt ttacggtcca gaaggcaaga actgggaaaa
     7681 aattgaaggt aaagaaaacc gtgttcgcgt tcttgatggc tacaaaggaa acactcacat
     7741 gggtggatgg aacactggta acaactggat cctttacatc aacgaaaacg ttacagacca
     7801 acaaatcgaa aattctaaga aagaattggc agaagctaaa gaatctccag cgcttggatt
     7861 tatcttcaat actgacaatg tgaaatctga aatctcagct attgctaaca caatgcaaca
     7921 atttgataca gctatcaaca ctggtactgt agacccagat aaagctattc cagaattgat
     7981 ggaaaaattg aaatctgaag gtgcctacga aaaagtattg aacgaaatgc aaaaacaata
     8041 cgatgaattc ttgaaaaaca aaaaataatc agctaaattg atttcgtgta ttcattccta
     8101 actcctaaaa taagaatcac tgctttcctc aggttggtct ggggagggca gtggtttttt
     8161 tggcacaagg atatagatat ccatgttttc tcttgtcctt attttaacca ttcaggaaat
     8221 ttcgagaatc ctctacaatt tccagtcaaa taaattgcat tcgttttctc aagcaggtat
     8281 actagtatgg ataaataaaa aatttagaaa atttaagaat agaaaagaga acaaatctta
     8341 tggcaaaaga tattcgtgtc ttactttact acctttatac tccaattgaa aatgcagagc
     8401 aatttgctgc agaccacttg gctttctgta aatcaatcgg ccttaaaggc cgtatcctag
     8461 tcgctgacga gggaattaac ggaacagttt caggtgacta tgaaacaact caaaaataca
     8521 tggactacgt tcacagcctt ccaggaatgg aagatctctg gttcaagatt gacgaagaaa
     8581 gtgaacaagc cttcaagaag atgtttgttc gctacaagaa agaaattgtc caccttggtt
     8641 tggaagacaa cgactttgac aatgacatca acccacttga aacaacaggt gcttacttgt
     8701 ctccaaaaga gttcaaagaa gcgcttcttg ataaagatac cgttgtcctt gacacacgta
     8761 acgattatga gtacgaccta ggacatttcc gtggggctat tcgcccagat attcgcaact
     8821 tccgtgagtt accacaatgg gtccgtgaca acaaagaaaa attcatggac aagcgtgtcg
     8881 tggtttactg tacaggtggt gttcgctgtg agaaattctc aggctggatg gttcgtgaag
     8941 gttacaaaga tgttggccaa ttgcacggag gaatcgcaac ttacggtaaa gacccagaag
     9001 ttcaaggtga gctttgggat gggaaaatgt acgtctttga cgagcgtatt gccgttgatg
     9061 tcaaccatgt caacccaacc atcgtaggga aagactggtt tgatggaaca ccatgtgaac
     9121 gttatgttaa ctgtggaaat cccttctgta accgtcgtat cttgacatca gaagaaaatg
     9181 aagacaagta ccttcgtgga tgctcacacg agtgccgtgt tcacccacgt aaccgctatg
     9241 tttcaaaaaa tgaattgaca caagctgaag tgattgagcg cctagccgct atcggtgaaa
     9301 gcttggatca ggcagctact gtataagatc aaacagtcct taggggctgt ttttctatgc
     9361 tttgtactca aaaatctaat actcaatgaa aatcaaagag caaactagga agctagccgc
     9421 aggctgctca aagcactgct ttgaggttgt agataagact gacgaagtca gttacatata
     9481 tctacggcaa ggcgaagctg acgcggtttg aagagatttt cgaagaatat aaagtttgtt
     9541 tttgtatctt tcagaaaaat aaggtatact gtatgtaaac gatttcaaag gagtccagtt
     9601 atggcgaaaa cattttttat tccaaataaa cagagcattt taggagaaca agagattttg
     9661 aatgccaagt cgatcttggc cttgctagac ggtttggagt cacatagcta tgatgtagtc
     9721 tatctccgtc agcctcttaa tcgtctcgag tatattgagt gtgcgatagt ggggcaatca
     9781 caatttctct ttaaggtcag ttatgctgat ggtcaaaagg cttaccgtgt cgatcttcct
     9841 gacctactaa caaagacaga ctggcagatt atcaagtcat ttttagatgc tttgcttgct
     9901 tatacaggga ctgatattga agggctagat ggttttgatt ttgaagctta tttccaagca
     9961 agtattcaag cctatctagc agaccctgta gctcgtttta cgatttgcca aggaattttt
    10021 aatcctattt tctttagtcg tgagaacttg aaaagctttt tagaggcaga tggcttggct
    10081 cagtttgaag cgcgtgtgcg tgcggttcaa gagacagatg cctactttgc gagagtttcc
    10141 ttctatcagg atggagaagg aaaagtgcat ggcgtttacc atctagctca aggagtcaag
    10201 acagttttac cgagagaacc gtttgttcct gcagcctata ttgagcaatt ggtggataag
    10261 gaagtccagt gggagattga cttggttcaa atcacaggag acggctctaa accagaagac
    10321 tatgaatcca tagctcgctt ggactatgca aaattcttag aggtattacc cccatctttt
    10381 taccaccaac tagacgccaa tcaaatagaa gtgcaaccca tattagacaa agattttaaa
    10441 acattagcac aagaaaagta aagcagaagc aggtcaatcg acttgctttt ttgaaataga
    10501 aaaatcctgc caaggatgac aggattgcta ctcaatgaaa atcggctcta taatatttgt
    10561 agtgggtaaa tcccctatgg atattatgga gcctattata acataaacga gtgacttttt
    10621 aagtaatgac tgcgcttttc aatgatggga gaggtatggt attggtttta atcacaaatt
    10681 atcagaaaat tttctatttt tttgttgaca atattttgaa tatagtatac aataatttca
    10741 ttaactcgac aatcactaga tatatgcaat ctaatcgtaa ttttatagga ggagtccgct
    10801 gatgtcaaac gagaatgcac agaatttgat gtggagataa tttaggatgg atgaatcaaa
    10861 atatttgtgc tatcttgaaa aatatgatgc tttaggctca ggacgattat tagctaaagt
    10921 taataatact tactatatgt ttaacaaaaa tcagattgaa ctcttacgat actcaaataa
    10981 aaatgctaaa aaagagagga aatatatgta aagttttcct gctatactag taataccata
    11041 gaccaattta ttgattattt ttacaaacaa ggaatacttg ttaagaaaaa ttcatttgat
    11101 gataatgggt tgaagttttt gtcaatatat cgcagattga caagattcta tattccacaa
    11161 aaattaaatg attatattgg acaaaaaaaa tctaaattta tacctttcct tccgaatcct
    11221 gtactaatta caaaagtaat gctatattgt agtcctattt tagctttatt tctttgttat
    11281 gcttgttatg atattcaact aaacatttca aaagttccaa gaaatattat cacattttta
    11341 gtaggaagcg tggtagctat tatacacgag ctattaataa tgatatatta tttgaagtca
    11401 gggagagtac ctggacgcat atatattaga attgtttatc tcgtagtcat atcttttgga
    11461 acagaatggg gtgctagtta tagtgaaaag aaagttttta gaacaacgat gttcctgttt
    11521 tctatgataa gtatttttta tttatctgct atatttttca tgatatttta cttattacag
    11581 tatttaaaac tttatacagc agcatattat acgagcatct atgctgttgg gacattgatt
    11641 tttgcattta ttaatgctta tccattctta ttaaagacag atggttatat actttatcaa
    11701 gaattttttg gaatttataa aatacgatca ttatttttta aaaccctttt ttattgtatt
    11761 ggaataagaa ataatctaaa attgcaagaa gtagtaaaga gaaataacct aaaaacgtat
    11821 atttgggatt tattttttat tatttctata attggattat tgtatatttt atatagtagt
    11881 attagattta ttatttgact ttggaggaaa aataaatgaa ttatattatt tgtgcctatt
    11941 ctattatttt aatgttttca gcttattttg gatataaaaa aaagcttgga gtatctgttg
    12001 tatcaatact tataaactta tgtttatgta cttcgacatt gtttaactta ttttattcaa
    12061 ttaactattt gaaattatta atatcaatct ttttaatatt actttcagtg agcttgctct
    12121 acgatagaaa gattagtgga aataaaatca attatagtca ccattgtatc agatttatta
    12181 ttcatgtact aataatttgt tatttatttc tataataaca agagtttcta tgaaagattc
    12241 gacacggata gtcaactgat ctaaaatttt aatactatat ctggaggtga tgaagcatga
    12301 caaaaaatat taatttcacc ctatttgata aggaaaacta tgaatcaaat aatcttgata
    12361 gtttgaatct caatatagct ctgagtcatc agattgatgg gaaagccacc aatatttcgt
    12421 aaggtcagaa acaaaaaatt ctattcatga ggagtttatc gcaagaaaag gatatctatt
    12481 cattcgatga gcctacagga aatttggaca gaaactcaac tgaattattt ctaaacgagg
    12541 ttgagaaatt agtgaacgag gaaaagattg ttattgtcgt gactcatgac aaggatgtta
    12601 ttgctagagc aagtaaagtt attaatatgg acgaatttca ttaaaagtta ataaatggag
    12661 attggtggtt tctaatctta attttacata taactagttt gcataatatt tggaataacg
    12721 aactttatag caacgctatc atactttgaa ctctaggaat aaaacccatc ctaggacaag
    12781 attttaaaac attagcacaa gaaaagtaaa gcagaagcag gtcaatcgac ttgctttttt
    12841 gacatagaaa aaatcctgcc aagaatgaca ggattgaatt ttaaagaaag gccaagatac
    12901 gaagataatc tccaatcagt gccacttcag ctacaaagaa gaggaggata ataactccgt
    12961 tcacaaggac agacaagaat aattgataga aggagtcggt ttcacttgct tgacttggtc
    13021 ttgtaatgat atggagactg gcaagcagaa tgattccaat gctaatcaca cacaagaggg
    13081 ccgtaaatcg taggctatca aagaaagcaa agaaactagc aatagcagtg aggaagattg
    13141 gaattgccaa gagttgacta tattgttgga gaaccttgtc tagcgtccag tccttttcct
    13201 ggtggataaa tcgtctcaca acgaaactac ccaagaggaa tgaaaagaag aagagtgttg
    13261 tcgctactag gatagagatg atagaaaaaa gagttaaagg agctagctgc tcagggaagc
    13321 gactgttaat gcttgctata tgtccatagt aagcatgttt gatgtgatag atactaaaga
    13381 aaaaggaaga tgcagaaaac agaatgagca agagaaaggc tgtgtaactg tgtgtgatac
    13441 ttgtttccaa cttacttgta ggagatttga tcgcttccac tagccaagac caaaaatcaa
    13501 gcacttgctc tttccattta tccctagatt ttggagcttg gtcggggata taaggacttt
    13561 ctaaagattt actgataaga agtggctctt tcgtggttgc tttttgctga ggaagagctt
    13621 cttggctctc ttcagctata gtgacttttt ctgtttcttt agaaaggtct ggctcttctt
    13681 cagtagaatt agatgccttc ttttcttcta tttctgttct cgcttcaccg ccttcaggag
    13741 tttcaatttt ctcttcttgc tggctttcca gttcgacttc agcttgagag acttcctcct
    13801 ctacttgagt attttttcca attggtgtat cgagatcggc tatcgtttct tcagccttgt
    13861 ctgcaacctc ttgagcttgc tcttcaggct tgttcttgct tgttgttttt acaaaatcat
    13921 tactttcaaa ccattcttgt ttcatggtag aacctccttt ttagttagat aaatatgctt
    13981 ccatagtagc agatgtaagc gtttttgtca acgtctgctt ggtgtggata ttagatcaat
    14041 attatcatca gatctcgcaa tgagttgatc cttgacatcg gttttttcag ttttgtaagg
    14101 gttgcttaat tccgtacctc ttgattcagg cttttctctt gtgaattgga agatagaacc
    14161 atagttgctt gagatgtccc agttaattcg ttggctttct ttctggtcta ggatgattct
    14221 gagataatct tcggcagtca gttcaacctt accatggact tggatatttt cagcgtggaa
    14281 gtgattctct gttgactcta gctgactatc tgtaagaact gtatcaaaga tattaacgat
    14341 attgggcgtt gtgagtttac tgtttttgat acgacttcct tcaattcgga ggatatagct
    14401 gtttgtattg agggtcgcat tttcaaggct agcatttatg atggtggttt gtccgcgatt
    14461 ggctgagatg ttgatccctt ttagagttct cccttttggt agtcggagaa taacttcttc
    14521 aaaacgacta gagtagctac ttgcgatatg aagaatccca ccaattccag aagagagaaa
    14581 cggagtttca gacagtttct tatcagtgag actcagagtt ctatcgttct gattggtgat
    14641 aagatcatgg tgagcagaaa gagatggatg gtaagaaatg tggatttgat catcgaaaga
    14701 gtctgtgatg gtgagcgtgt gttggtggag agtaatttct aggttttcga cttccttgcc
    14761 aaaggttagc ttttccgtac ggctatcata gacaggttct ttggacatgg aaagtaggct
    14821 cttaatcccg tcagattgga tacctacaaa aagcagaata aagccgataa cggtagtcac
    14881 cacaccaaag atgagaaatc cttttgtcca tttacgcatg ctgattacct ctctttcctt
    14941 ttttaagaac aaattgtacc agacgaacaa tgagtagacc gaagaagcga gctacatagg
    15001 aaatgccaag taaaactagc gaagaagcac cgatagccag taaaccagaa ccaaaaatca
    15061 agataaaggc tgatttggct tgggcgagga cagtgaaact ttcaactaaa aataggaatc
    15121 cgccgatgat acccagtatg gaaactgcaa agaaagccag aatgacagtc aaagcggcta
    15181 caaggattgc gaacagggtc acgaggatgg cgattcccag aggaatgccg ataggtgctg
    15241 caaggagggc taacaaggcg atatgtaaaa tttgtcggtt atttttttga gcgggtgctt
    15301 cattgatttt tttatcgaga agattggata gaacttcgtg ggccacttct ttgggagttc
    15361 ccaaactagc gatgagttct tcttctcctt cgactccagc atcgtcaaag agctctctga
    15421 aatagtccat ggcttcgata cggtcagctt caggtagttt cttgagatag agttctagct
    15481 gagtcaggta ttcagttctt gtcatggcgg atactccctt ctatgatgcc attgatggtg
    15541 tctgtataga gtgtccattc atcttttagg gtcaagagct gctctatacc accgtttgtc
    15601 aaggagtagt atttgcgcat gcgaccttgg aactctctag aataggttgt cagaaagcta
    15661 ttgccttcca attttttgag aatgggatag agtgtggatt ctttgatatt agcgatcagc
    15721 ttaatggttt ggctaatctc ataaccataa gaatcaccct gctccagtac agccaagatg
    15781 agaaattcaa tcaaggcaga ggatgttgga aagtacatgg gaaacctcct tttctaatgt
    15841 gtaagatttt tatatataat ttttctacac atacattgta catctaaaag aaagccctgt
    15901 caagagaaat gtgtaaaatt tttatatata aaaaacttct agctaaaact agaagtttaa
    15961 aggatcttat ccgctctgtc cactgtaaag agggccacag tcatcaggat atcgatgagc
    16021 aagagggcag ctacagctgg tacccaagag tggaataggt caaaactgta accaaagagg
    16081 gttggcccaa aggctgctag gatatagcct cctgtttgag ataggccgga caattgggct
    16141 gtcttttcag gggcgcttgt cttgagtgaa aagttgacca tgagataagg gaagagggcg
    16201 ctggttgcgg ttccgatgag gagatggatg gcaagccagt aaatgaaatt attgattggg
    16261 aaaaagagca tggaaatgcc gaccacacca gctagtgaaa ccagagtgag catgagctga
    16321 cggttgcgag tagataaact ggttgtcagg cttgggatgg tcattgaaaa aggaatgcta
    16381 atcagagata agatagaagt cagcaagcca gcttcgtgac tggatagacc tgcatggata
    16441 gacatggtag gtaaccaggt catggcggtg taaaagatca aggattgaaa acctgaaaag
    16501 ataataattg cccaaacctg tttattacgc atgaccttta tttgactttt ttgtttggtt
    16561 tgtggagcta gtctatgatt atagcggtga tttgggagcc agaccaaaaa agttgctaga
    16621 cagagtaacg tgaggaggag gataagtcct ttccaagaac tggcttgtgt aatgggcaca
    16681 gctagatagg aagccagagc cgttgcaatc cccatagacg ttacatataa ggtggtcaga
    16741 aaaccaattt tctttggttg attggcttgg ataagactag gaagcaggac attgatgact
    16801 gcgacacttg ccccaaccat caaggttcct agatagagca ggggcagatt gattagtcga
    16861 atgagtgagc cgatggtcaa gaagaagagg ctgtaggtga agagatgctc caatccgatt
    16921 ttctgagcca gttgggtaga aaatggtgaa aagagggtaa acataaggag aggcaggctg
    16981 gtcaagacac caagcgaact aacttctacc tccagacctt gcgaaatatt tcccaaaata
    17041 atgggtaaaa cagtgaaagg agttcgcaag gaaacaccaa tcaggataat acctggaaca
    17101 aaaaagagtg attgcttttt catataatac ctcttctagc tgattttaat aacagcttat
    17161 tttaaggctt tttcactata atgtcaagta aggtttctgg ctttcaagat aaaaatggga
    17221 aagtcttgaa aattatgata gaatggtgga aggaaaaatt caggagagta gtagtgactc
    17281 aaaatgttga aagtcttctc gtatccattg taatcagtgc atacaatgaa gaaaaatatc
    17341 tgcctggtct aattgaagac ttaaaaaatc aaacttatcc taaagagaat attgaaattc
    17401 tatttataaa tgctatgtcc acagatggga ccacagctat cattcagcaa tttataaagg
    17461 aagatacaga gtttaactca attagattgt ataacaatcc taagaaaaat caagctagtg
    17521 gttttaacct gggagttaaa cattctgtag gggaccttat tttaaaaatt gatgctcatt
    17581 caaaagttac tgagactttt gtaatgaaca atgtggctat tattcaacaa ggtgaatttg
    17641 tctgtggggg gcctagaccg acgattgtcg aaggaaaagg aaaatgggca gagaccttgc
    17701 atcttgttga ggaaaatatg tttggcagta gcattgccaa ttatcgaaat agttccgagg
    17761 atagatatgt ttcttctatt tttcatggga tgtataaacg agaggttttc cagaaggttg
    17821 gtttagtaaa tgagcaactt ggccgaactg aagataatga tattcattat agaattcgag
    17881 aacatggtta taaaatccgc tatagcccaa gtattctatc ttatcagtat attcgaccaa
    17941 cattcaagaa aatgctgcat caaaagtatt caaatggttt gtggattggc ttgacaagtc
    18001 atgttcagtt taagtgttta tcattatttc actatgttcc ttgtttattt gttttgagtc
    18061 ttgtgtttag tctagcattg ttaccgatca cattcgtatt cataacttta ctattaggtg
    18121 cctattttct acttttgtca ttactcactt tgctgacttt attaaaacat aaaaatggat
    18181 ttctaattgt gatgcccttt cttttatttt ccattcactt tgcttatggc cttgggacga
    18241 ttgtaggttt aattagagga tttaaatgga agaaggagta caagagaaca ataatttatt
    18301 tggataaaat aagccaaata aataaaaata tgctataata acaatatagt aaaactcttt
    18361 taaggaggag tagatttcta tgaataaaaa actaacagat tatgtgattg atctggtgga
    18421 aattttaaat aaacaacaaa agcaggtttt ctggggaata tttgatattt tcagtatggt
    18481 ggtttccatc attgtatctt atattttatt ttatgggctg attaatccag cacctgttga
    18541 ctacattatc tatacgagtt tggccttctt gttctatcaa ttgatgattg gtttttgggg
    18601 gttgaacgcg agcattagtc gttacagcaa gattacggat ttcatgaaaa tcttttttgg
    18661 tgtgactgct agcagtgtct tgtcatatag tatctgttat gccttcttgc cactcttctc
    18721 catccgtttc atcattctct ttatcttgtt gagtaccttc ttgattttat tgccacggat
    18781 tacttggcag ttaatctact ccagacgcaa aaaaggtagt ggtgatggag aacaccgtcg
    18841 gaccttcttg attggtgccg gtgatggtgg ggctcttttt atggatagtt accaacatcc
    18901 aaccagtgaa ttagaactgg tcggtatttt ggataaggat tctaagaaaa agggtcaaaa
    18961 acttggtggt attcctgttt tgggctctta tgacaatctg cctgaattag ccaaacgcca
    19021 tcaaatcgag cgtgtcatcg ttgcgattcc gtcgctggat ccgtcagaat atgagcgtat
    19081 cttgcagatg tgtaataagc tgggtgtcaa atgttacaag atgcctaagg ttgaaactgt
    19141 tgttcagggc cttcaccaag caggtactgg cttccaaaaa attgatatta cggacctttt
    19201 gggtcgtcag gaaatccgtc ttgacgaatc gcgtctgggt gcagaactga caggtaagac
    19261 catcttagtc acaggagctg gaggttcaat cggttctgaa atctgtcgtc aagttagtcg
    19321 cttcaatcct gaacgcattg tcttgctcgg tcatggggaa aactcaatct accttgttta
    19381 tcatgaattg attcgtaagt tccaagggat tgattatgta cctgtgattg cggacattca
    19441 agactatgat cgtttgttgc aagtctttga gcagtacaaa cctgctattg tttatcatgc
    19501 ggctgcccac aagcatgttc ctatgatgga gcgcaatcca aaagaagcct tcaaaaacaa
    19561 tatccgtgga acttacaatg ttgctaaggc tgttgatgaa gctaaagtgt ctaagatggt
    19621 tatgatttcg acagataagg cagtcaatcc accaaatgtt atgggagcaa ccaagcgcgt
    19681 ggcggagttg attgtcactg gctttaacca acgtagccaa tcaacctact gtgcagttcg
    19741 ttttgggaat gttcttggta gccgtggtag tgtcattcca gtctttgaac gtcagattgc
    19801 tgaaggtggg cctgtaacgg tgacagactt ccgcatgacc cgttacttta tgaccattcc
    19861 agaagctagc cgtctggtta tccatgctgg tgcttatgcc aaagatgggg aagtctttat
    19921 ccttgatatg ggcaaaccag tcaagattta tgacttggcc aagaagatgg tgcttctaag
    19981 tggccacact gaaagtgaaa ttccaatcgt tgaagttgga atccgcccag gtgaaaaact
    20041 ctacgaagaa ctcttggtat caaccgaact cgttgataat caagttatgg ataagatttt
    20101 cgttggtaag gttaatgtca tgcctttaga atccatcaat caaaagattg gagagttccg
    20161 cactctcagt ggagatgagt tgaagcaagc tattatcgcc tttgctaatc aaacaaccca
    20221 cattgaataa aaaagaaaaa cgcatagtat caagttacac aaccttggta atatgcgttt
    20281 tattatgtag agacttatac tcttcgaaaa tctcttcaaa ccacgtcaac gtcgccttgc
    20341 cgtagatggt tactgacttc gtcagttcta tccacaacct caaaacagtg ttttgagctg
    20401 acttcgtcag ttccatccac aaccttaaaa caatgttttg agctgacttc gtcagttcta
    20461 tctgcaacct caaaacagtg ttttgagcag cccgcagcta gtttcctagt ttgctctttg
    20521 attttcattg agtattactt cattttcttc tgaaatggaa ttgttaccca gtctatgcta
    20581 ttgaaaatac gccaaaactt ctaagggttt gtgagcgata taatcaggtt gatagtttag
    20641 tagatctgct tgctctccaa atccccaagt gatggccaat ttctgaatac ctgtttctcg
    20701 agctcccagc atatcaaact tggtatctcc gatgatgatg gcttgttctg gtgctagttg
    20761 atgtgtctgc aaggcttggt gaatgacatc tgccttatgg ggtgcttcag ggctagaacc
    20821 ataaatgcca tcaaagaaat gatggatttc caagtttttt gccatgtctt gagcagtaga
    20881 tgtatccttt gtcgtggtga tgtagagtgg ataactgctc gataactcct caagcaagtc
    20941 tataatctga ggaaagagtt gagcttcata gatgcctttt gccttatagt aagaacgata
    21001 tatctgcacg gcttcagaaa tttggtcttt ggacaggcag gtcgcaaaac tactttcgag
    21061 aggtggtccc ataaaaccac gaatagtttt ggcatcaggg ctaggcaccc ccagctcttt
    21121 aaaggtatag gtaaaggcat tgtgaatccc gatagaacta tcaacgaggg ttccatccaa
    21181 atcgaaaaaa attgctgtga tagaggtcat ggtttctcct atttgataag cttattctcc
    21241 gaaaatttct ttttggaggc gacgaccagt aggggtggta gcgagtccac cttcagctgt
    21301 ttcacgaaag gcagttggca tgcttgctcc tacttggtac atggcatcga tcacttcatc
    21361 cacagggatt ttagattcga tacctgccaa ggccatgtct gctgcgatga aagcaaagct
    21421 agctcccatg gcattacgtt tgacacaggg aacttcgacc aaacctgcaa cagggtcaca
    21481 gatgaggcct agcatatttt taatgacaaa ggcaatagct tgactggcct gataaggtgt
    21541 tccacctgca gccagagtca aggcggcagc actcatagca gaggctgaac caacttcagc
    21601 ttgacaccca ccctcagcac ctgagatgga ggcattgttt gcgatgacta gtccaaaggc
    21661 accagcagca aagaggaaat ccaattgttg ctcgtggctg aggtctaatt tttcaatagc
    21721 agcagtgaga acggaaggga gacagccagc acttccagcg gttggagtgg cacagaccaa
    21781 gcccattttg gcattgtgtt cattgactgc gatagcattt cgggcagcag agagaatcgt
    21841 gtaatctgat aaagtttttt cgtttttgat gtagtgatcc aatttggcag catctccacc
    21901 tgtcaggcca ctacgagatt tattttcatt gaggccaagt tggacagagg ctttcataac
    21961 ttccagattg cgttccatga gaaggaagac ttcttcacgt tcgcgaccgg tcaattcaaa
    22021 ctctgttgta atcatgagtt ctgcgacatt tccttgaaag tctagatctg cttgctcgac
    22081 caattctttg atagaataaa acatgcttcc tcctatttaa agaaattgac attgtggaga
    22141 tgagggattt ttcgaatttc ttcgatagcc tcatcacagt tgcgactgtc aacttcgata
    22201 atcataatgg ctttttcacc agctttttca cgagtgacat tcatctgggc gatattgata
    22261 ccatagcggg aaagcgcctc tgtaacaagg gcaatcatac ctggaatatc ttgatgaacg
    22321 atgatgatag tcggtgtatt catattgaga gagacggcaa aaccattgag ttcggttacc
    22381 tgaatatttc ctccaccgat agaaatacca gtcacgctga tggtcttgtg ggcattttta
    22441 acagtaattt tagtggtgtt agggtgaggg gcattgctgt ctttctgaat ggtccagaca
    22501 atcttgatac cacgcttgtg ggcaatttcc agactatttg gaatttcagg atcatctgta
    22561 tccattccta aaatacctgc aacaagggct aggtctgttc cgtgaccacg ataggtcttg
    22621 gcaaatgagt taaaaagttg gaattcaact tctgtcggag tatcatcaaa aatggaagag
    22681 acaatcttcc caatacgaac agcaccagcg gtatggctac tagatgggcc aatcataact
    22741 ggtccgatga tatcaaagac agattgaaaa cgaagtgatt tcatcagttt ccccttataa
    22801 aaattcttat ctctattata tcaaagaatg aggggcttgg ctttaattgt ggatgaaaac
    22861 ctttctaata cctcaaatag cataaaaata gtatctttta tgacaaaaaa caccttattt
    22921 agggaaataa aaaataattt tgtaatattt ctacataaaa gtgtcaagaa acggtaatat
    22981 ttaaagggta tgatagaact atagaaagaa ggagaatttt cgaatatgaa atcaataact
    23041 aaaaagatta aagcaactct tgcaggagta gctgccttgt ttgcagtatt tgctccatca
    23101 tttgtatctg ctcaagaatc atcaacttac actgttaaag aaggtgatac actttcagaa
    23161 atcgctgaaa ctcacaacac aacagttgaa aaattggcag aaaacaacca cattgataac
    23221 attcatttga tttatgttga tcaagagttg gttatcgatg gccctgtagc gcctgttgca
    23281 acaccagcgc cagctactta tgcggcacca gccgctcaag atgaaactgt ttcagctcca
    23341 gtagtaagtg aaacagttgt ttcaactgta agcggatctg aagcagaagc caaagaatgg
    23401 atcgctcaaa aagaatcagg tggtagctat acagctacaa atggacgtta tatcggacgt
    23461 taccaattaa cagattcata cctgaacggt gactactcag ctgaaaacca agaacgtgta
    23521 gcagatgcct acgttgcagg acgttacggt tcatggactg ctgctaaaaa cttctggctt
    23581 aacaatggct ggtattaaga actaacgaac aaataatatg taaagagtcg aggaaatccc
    23641 tcgacttttt ttataatttc tttggttgat aatgggtctc tacttctttt ttgagatgag
    23701 acagcataga agtttcctcg gtcagctcta ggagtgagaa ccctttttgg ataagtttcg
    23761 catcatccct acaaatccca atacggacat agcagatagc cagcctatcg tagcttttct
    23821 tattcttggc gtcctccagt aaagtgtagc agatttgctt acacatgttt ttatcttgat
    23881 tgtatagata gagtgtggaa aggtttaata gaattgtcat tcgcaagtca tataaatgtt
    23941 gatagttttt atagacttct aagcgttgca agattttctc ggattattga caaataaacg
    24001 gacattctga tagacgattg ccctagcggc ttagtgtaaa ctttacaaat ttggcttgta
    24061 atttttttat aaaattcact tcagttactt gacagttatt atattttcgc ttatgcttat
    24121 tatatagata aaaggacggg ataggagttt aaaaatttga aagcgctatc cataatcata
    24181 acgcataatt ttctcctttt cgtgaaaaaa gttaacgtaa ttttgaaatg agcttaataa
    24241 gaggtactat gtaggtagaa aataaagata ggagaaaaag tatgaataaa aaaatatttt
    24301 gtattctagt atgtattata tcattgatta gtctagctat aatctttcca tggggctggt
    24361 cgatataatg taagggagct tgagttgtta gtggaggata aaatgttaag agtaatagta
    24421 gttattcaat ctttagtaat aatactgctt gctgttgctt tattattatc tcggaaaaac
    24481 tttgattcgt taaatgttgt tcttataatg atgatcgtat cacaattgtt gttattagta
    24541 tatttgataa aatcagggaa tcagtgatta gctgttattt gaattaagta aactgttaag
    24601 cttcaagcag taactggttt taaatattta aaataagata aagaaaggaa gtctaattta
    24661 ggtaactaaa caaagcctgc gatcacttgt taggaaacca tcctaaccat gcttaataaa
    24721 aaaggagaaa ataaatggaa cttgtattac caaataatta tgttgtgatt gatgaagaag
    24781 agatgatgta ccttggtggg ggagcttatt taagcaagcg tgcttgtcaa ggaatttgcg
    24841 cagctttagc tatgagtcca ggaactttta tagcattagc tggagctgca gttttaacca
    24901 aaaaactaat aaactatatt aaagttggag gccttggagg ttggcttatt ggtgcagcag
    24961 caggtgtatt ggctggggcg gcaggaagaa tagcttactg tattggatat ggtgctctta
    25021 atagaggttg tgatattaac gggaaccctt atccttggga tggattcata tctgcgacag
    25081 taagatgagt aatgtagata agattcgaaa aatacacatt atcgtatgtt gg
//
LOCUS       DBEJHE010000027        24236 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC4 isolate 671759
            SAMN38261586-rid24793303.denovo.27, whole genome shotgun sequence.
ACCESSION   DBEJHE010000027 DBEJHE010000000
VERSION     DBEJHE010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261586
            Sequence Read Archive: SRR26833752
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 24236)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24236)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576136.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576136.1
            Genome Coverage       :: 109x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 19:48:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,067
            CDSs (total)                      :: 2,029
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 131
            CDSs (without protein)            :: 131
            Pseudo Genes (ambiguous residues) :: 0 of 131
            Pseudo Genes (frameshifted)       :: 64 of 131
            Pseudo Genes (incomplete)         :: 59 of 131
            Pseudo Genes (internal stop)      :: 46 of 131
            Pseudo Genes (multiple problems)  :: 32 of 131
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24236
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261586-rid24793303.denovo.27"
                     /strain="GPSC4"
                     /isolate="671759"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(201..2459)
                     /locus_tag="ACL3EZ_001531"
     CDS             complement(201..2459)
                     /locus_tag="ACL3EZ_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HGR0393078.1"
                     /translation="MLCQNCKINDSTIHLYTNLNGKQKQIDLCQNCYKIIKTDPNNSL
                     FKGMTDLNNRDFDPFGDFFNDLNNFRPSSNTPPIPPTQSGGGYGGNGGYGSQNRGSAQ
                     TPPPSQEKGLLEEFGINVTEIARRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIGEP
                     GVGKTAVVEGLAQKIVDGDVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEI
                     RKREDIILFIDEIHEIVGAGSASDGNMDAGNILKPALARGELQLVGATTLNEYRIIEK
                     DAALERRMQPVKVDEPTVDETITILKGIQKKYEDYHHVQYTDAAIEAAATLSNRYIQD
                     RFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKSQATREEDFEKAAYFRD
                     QIAKYKEMQKKKITDQDTPIISEKTIEHIIEQKTNIPVGDLKEKEQSQLIHLAEDLKS
                     HVIGQDDAVDKIAKAIRRNRVGLGTPNRPIGSFLFVGPTGVGKTELSKQLAIELFGSA
                     DSMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTEKVRHNPYSLILLDEVEKAHP
                     DVMHMFLQVLDDGRLTDGQGRTVSFKDAIIIMTSNAGTGKTEASVGFGAAREGRTNSV
                     LGELGNFFSPEFMNRFDGIIEFKALSKDNLLQIVELMLADVNKRLSSNNIRLDVTDKV
                     KEKLVDLGYDPKMGARPLRRTIQDYIEDTITDYYLENPSEKDLKAVMTSKGNIQIKSA
                     KKAEVKSSEKEK"
     gene            complement(2688..2918)
                     /locus_tag="ACL3EZ_001532"
     CDS             complement(2688..2918)
                     /locus_tag="ACL3EZ_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1797 family protein"
                     /protein_id="HGR0393079.1"
                     /translation="MESHLVRIINRLEAMANDGGNLKRNFEREGVVVAEVAYSHDEEN
                     GPIFTLRDVEDRETYTFDSIDLIAMEIYELLY"
     gene            3108..3791
                     /locus_tag="ACL3EZ_001533"
     CDS             3108..3791
                     /locus_tag="ACL3EZ_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001011621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HGR0393080.1"
                     /translation="MNFSFLPKYLPYFNYGAVVTILISICVIFLGTILGVVLAFGQRS
                     KFKPLVWLANLYVWIFRGTPMMVQIMIAFALMHINAPTIQIGILGVDFSRLIPGILII
                     SMNSGAYVSETVRAGINAVPKGQLEAAYSLGIRPKNAMRYVILPQAVKNILPALGNEF
                     ITIIKDSSLLSAIGVMELWNGATTVSTTTYLPLTPLLFAAFYYLIMTSILTVALKAFE
                     KHMGQGDKK"
     gene            3791..4525
                     /locus_tag="ACL3EZ_001534"
     CDS             3791..4525
                     /locus_tag="ACL3EZ_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HGR0393081.1"
                     /translation="MTETLIKIENLHKSFGKNEVLKGINLEIKRGEVVVIIGPSGSGK
                     STLLRSMNLLEEATKGKVIFEGVDITDKKNDLFAMREKMGMVFQQFNLFPNMTVMENI
                     TLSPIKTKGESRKVAEKRAQELLEKVGLPDKADAYPQSLSGGQQQRIAIARGLAMEPD
                     VLLFDEPTSALDPEMVGEVLAVMQDLAKSGMTMVIVTHEMGFAREVADRVIFMADGVV
                     VEDGTPEQIFEQTQEQRTKDFLSKVL"
     gene            4679..5536
                     /locus_tag="ACL3EZ_001535"
     CDS             4679..5536
                     /locus_tag="ACL3EZ_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004488 - methylenetetrahydrofolate
                     dehydrogenase (NADP+) activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HGR0393082.1"
                     /translation="MTQIIDGKALAAKLQGQLAEKTAKLKEETALVPGLVVILVGDNP
                     ASQVYVRNKERSALAAGSRSEVVRVPETITQEELLDLIAKYNQDPAWHGILVQLPLPK
                     HIDEEAVLLAIDPEKDVDGFHPLNMGRLWSGHPVMIPSTPAGIMEMFHEYGIDLEGKN
                     AVVIGRSNIVGKPMAQLLLAKNATVTLTHSRTHNLAKVAAKADILVVAIGRAKFVTAD
                     FVKPGAVVIDVGMNRDENGKLCGDVDYEAVAPLASYITPVPGGVGPMTITMLMEQTYQ
                     AALRTLDRK"
     gene            5678..6550
                     /locus_tag="ACL3EZ_001536"
     CDS             5678..6550
                     /locus_tag="ACL3EZ_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000864675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016836 - hydro-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HGR0393083.1"
                     /translation="MKVINQTLLEKVIIERSRSSHKGDYGRLLLLGGTYPYGGAIIMA
                     ALAAVKSGAGLVTVGTDRENIPALHSHLPEPMAFSLQDQQLLKEQLEKAEVVLLGPGL
                     RDDASGENLVKQVFVNLSQNQILIVDGGALTILARTSLSFPSSQLILTPHQKEWEKLS
                     GITIEKQKEDATASVLTSFPQGTILVEKGPATRIWEVGQSDYYQLQVGGPYQATGGMG
                     DTLAGMIAGFVGQFRQASLYERVAVATHLHSAIAQELSQENYVVLPTEISRYLPKIMK
                     IICQQERVSKDKLV"
     gene            6832..7515
                     /gene="rpiA"
                     /locus_tag="ACL3EZ_001537"
     CDS             6832..7515
                     /gene="rpiA"
                     /locus_tag="ACL3EZ_001537"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004751 - ribose-5-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0009052 - pentose-phosphate shunt,
                     non-oxidative branch [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HGR0393084.1"
                     /translation="MENLKKMAGIKAAEFVSDGMVVGLGTGSTAYYFVEEIGRRIKEE
                     GLQITAVTTSSVTTKQAEGLNIPLKSIDQVDFVDVTVDGADEVDSQFNGIKGGGGALL
                     MEKVVATPSKEYIWVVDESKLVEKLGAFKLPVEVVQYGAEQVFRHFERAGYKPSFREK
                     DGQRFVTDMQNFIIDLALDVIENPIAFGQELDHVVGVVEHGLFNQMVDKVIVAGRDGV
                     QISTSKKGK"
     gene            7529..8740
                     /locus_tag="ACL3EZ_001538"
     CDS             7529..8740
                     /locus_tag="ACL3EZ_001538"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019318858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008973 - phosphopentomutase activity
                     [Evidence IEA];
                     GO_process: GO:0009117 - nucleotide metabolic process
                     [Evidence IEA];
                     GO_process: GO:0043094 - cellular metabolic compound
                     salvage [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HGR0393085.1"
                     /translation="MSKFNRIHLVVLDSVGIGAAPDANNFVNAGVPDGASDTLGHISK
                     TVGLNVPNMAKIGLGNIPRETPLKTVAAEINPTGYATKLEEVSLGKDTMTGHWEIMGL
                     NITEPFDTFWNGFPEEILTKIEEFSGRKVIREANKPYSGTAVIDDFGPRQMETGELII
                     YTSADPVLQIAAHEDIIPLDELYRICEYARSITLERPALLGRIIARPYVGEPGNFTRT
                     ANRRDLAVSPFSPTVLDKLNEAGIDTYAVGKINDIFNGAGINHDMGHNKSNSHGIDTL
                     LKTMGLAEFEKGFSFTNLVDFDALYGHRRNAHGYRDCLHEFDERLPEIIAAMRENDLL
                     LITADHGNDPTYAGTDHTREYIPLLAYSPAFKGNGLIPVGHFADISATVADNFGVETA
                     MIGESFLDKLV"
     gene            8742..9299
                     /locus_tag="ACL3EZ_001539"
                     /pseudo
     CDS             8742..9299
                     /locus_tag="ACL3EZ_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893195.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
     gene            9299..10108
                     /locus_tag="ACL3EZ_001540"
     CDS             9299..10108
                     /locus_tag="ACL3EZ_001540"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004731 - purine-nucleoside phosphorylase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HGR0393086.1"
                     /translation="MTFLNKIHETATFLKEKGIAAPEFGLILGSGLGELAEEIENPVV
                     VDYAEIPNWGRSTVVGHAGKLVYGELAGRKVLALQGRFHFYEGNPLEVVTFPVRVMKV
                     LGCEGVIVTNAAGGIGFGPGTLMAISDHINMTGQNPLMGENLDDFGPRFPDMSRAYTP
                     EYRATAHEVAKKLNIKLDEGVYIGVTGPTYETPAEIRSYKTLGADAVGMSTVPEVIVA
                     AHSGLKVLGISCITNFAAGFQEELNHEEVVEVTERVKGDFKGLLKAILAEL"
     gene            10584..10980
                     /locus_tag="ACL3EZ_001541"
                     /pseudo
     CDS             10584..10980
                     /locus_tag="ACL3EZ_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887334.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin family protein"
     gene            11293..11568
                     /locus_tag="ACL3EZ_001542"
     CDS             11293..11568
                     /locus_tag="ACL3EZ_001542"
                     /inference="COORDINATES: protein motif:HMM:NF012956.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
                     /protein_id="HGR0393087.1"
                     /translation="MENIALGKQVTQSSTAFGGDARRAVDGKVDGNYGHNSVTHTNFQ
                     SKPWWQVDLAKEETIRQINIYNRTDTAQDRLANFDVILLDSSGKEIE"
     gene            11593..12106
                     /locus_tag="ACL3EZ_001543"
                     /pseudo
     CDS             11593..12106
                     /locus_tag="ACL3EZ_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001275913.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-activated cytolysin C-terminal
                     domain-containing protein"
     gene            12760..13470
                     /gene="deoD"
                     /locus_tag="ACL3EZ_001544"
     CDS             12760..13470
                     /gene="deoD"
                     /locus_tag="ACL3EZ_001544"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004731 - purine-nucleoside phosphorylase
                     activity [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HGR0393088.1"
                     /translation="MSIHIAAQQGEIADKILLPGDPLRAKFIAENFLDDAVCFNEVRN
                     MFGYTGTYKGHCVSVMGTGMGMPSISIYARELIVDYGVKKLIRVGTAGSLNEEVHVRE
                     LVLAQAAATNSNIVRNDWPQYDFPQIASFDLLDKAYHIAKKFGMTTHVGNVLSSDVFY
                     SNYFEKNIELGKWGVKAVEMEAAALYYLAAQYHVDALAIMTISDSLVNPDEDTTAEER
                     QNTFTDMMKVGLETLIAE"
     gene            complement(13493..14017)
                     /locus_tag="ACL3EZ_001545"
     CDS             complement(13493..14017)
                     /locus_tag="ACL3EZ_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topology modulation protein"
                     /protein_id="HGR0393089.1"
                     /translation="MKITIIGYSGSGKSTLAEKLSNYYSIPKLHMDTLQFQPGWQDSD
                     CEWMLTEIKNFLTKHKAWVIDGNYSWCYYQERMQEADQIIFLNFLPLTCLFRAFKRYL
                     KYRGKVRESMAADCPERFEWEFIRWILWDGRSKTQKENYQKLCQEYSHKVTILRNQRE
                     LDQFLDKKRKSYNS"
     gene            complement(14070..14306)
                     /gene="rpsT"
                     /locus_tag="ACL3EZ_001546"
     CDS             complement(14070..14306)
                     /gene="rpsT"
                     /locus_tag="ACL3EZ_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001274003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HGR0393090.1"
                     /translation="MANIKSAIKRAELNVKQNEKNSAQKSAMRTAIKAFEANPSEELF
                     RAASSAIDKAETKGLIHKNKASRDKARLSAKLAK"
     gene            complement(14374..15294)
                     /gene="coaA"
                     /locus_tag="ACL3EZ_001547"
     CDS             complement(14374..15294)
                     /gene="coaA"
                     /locus_tag="ACL3EZ_001547"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004594 - pantothenate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HGR0393091.1"
                     /translation="MTNEFLHFEKISRQTWQSLHRKTTPPLTEEELESIKSFNDQISL
                     QDVTDIYLPLAHLIQIYKRTKEDLAFSKGIFLQRESKSQPFIIGVSGSVAVGKSTTSR
                     LLQILLSRTFTDATVELVTTDGFLYPNQTLIEQGILNRKGFPESYDMEALLNFLDRIK
                     NGQDVDIPVYSHEVYDIVPEEKQSVKAADFVIVEGINVFQNPQNNRLYITDFFDFSIY
                     VDAGVDDIESWYLDRFLKMLSLAQNDPDSYYYRFTQMPIGEVEAFAHQVWTSINLTNL
                     QNYIEPTRNRAEVILHKSKNHEIDEIYLKK"
     gene            15492..15896
                     /locus_tag="ACL3EZ_001548"
     CDS             15492..15896
                     /locus_tag="ACL3EZ_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0393092.1"
                     /translation="MKILKRYILELCFILSFALPFIKGANADNGICFVETYYGFTFLM
                     EHAIVTAVFIYSFSIAFLLKKRWAKWIAAGSYCFLVLWIATEGYFFRMSLEDLIRLWT
                     SLEILTQTYQLGFYLNILLGILLIIKYFKVKQ"
     gene            16103..16693
                     /locus_tag="ACL3EZ_001549"
     CDS             16103..16693
                     /locus_tag="ACL3EZ_001549"
                     /EC_number="2.1.1.172"
                     /EC_number="2.1.1.174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0052916 - 23S rRNA
                     (guanine(1835)-N(2))-methyltransferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGR0393093.1"
                     /translation="MSKMYYAENPDAAHDIHELRVELLGQKMTFLTDAGVFSKKIVDF
                     GSQLLLKCLEVNQGETVLDVGCGYGPLGLSLAKAYGVQATMVDINTRALDLARRNAEK
                     NNAKATIFQSNIYEQVEGHFDHVISNPPIRAGKQVVHEIIEKSKDFLETSGDLTIVIQ
                     KKQGAPSAKSKMEGVFGNCEILKKDKGYYILRSVKE"
     gene            16690..17967
                     /locus_tag="ACL3EZ_001550"
     CDS             16690..17967
                     /locus_tag="ACL3EZ_001550"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001202959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016154 - pyrimidine-nucleoside
                     phosphorylase activity [Evidence IEA];
                     GO_process: GO:0006213 - pyrimidine nucleoside metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HGR0393094.1"
                     /translation="MRAVDLIQKKRDGQELTSSEIEWLVEGYVSGTVPDYQMSAFAMA
                     VYFKGMTTREISDLTMNMVKTGQEFDLSAIDGVKVDKHSTGGVGDKVTLILVPLVASF
                     GVPVAKMSGRGLGHTGGTIDKLESIKGYQVERSQEDFIRQVQDIGVSVIGQSDQLVKA
                     DKLLYALRDVTATVDTIPLIASSVMSKKIAAGADAILLDVTVGEGAFMKTVDEARELA
                     QTMVDLGKVVGRKTVAVITDMSQPLGRAIGNRLEILEALEILQGQGRQDITHFICELA
                     QIMLGLANVNKTVEEVRQHLENGQALAKFEEMVQAQGGDLEDLYRPVNVAHVVEIPAQ
                     ETGVISALPAMDFGLYAMRLGAGRAVKSDALDYETGIVFEKKIGDSVQKGEIVAKVYT
                     NEKIPPQLVTDFQKCVKISDEVKKIREIVEIIS"
     gene            17985..18647
                     /gene="deoC"
                     /locus_tag="ACL3EZ_001551"
     CDS             17985..18647
                     /gene="deoC"
                     /locus_tag="ACL3EZ_001551"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004139 - deoxyribose-phosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0009264 - deoxyribonucleotide catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HGR0393095.1"
                     /translation="MKLNKYIDHTLLKQDAKKKQIDSLLSEAREYGFASVCVNPTWVE
                     HAKKGLEGTDVKVCTVVGFPLGATTSAVKAFETKEAIQNGADEIDMVINVGALKSGNL
                     ALVESDIRAVVEASGDKLVKVIIEACLLTDQEKIVVCQLAQKAGADFVKTSTGFSTGG
                     ATIADVTLMRETVGSDMGVKAAGGARSYADALAFVEAGATRIGTSAGVAILKGELADG
                     DY"
     gene            18634..19023
                     /locus_tag="ACL3EZ_001552"
     CDS             18634..19023
                     /locus_tag="ACL3EZ_001552"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004126 - cytidine deaminase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0009972 - cytidine deamination [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HGR0393096.1"
                     /translation="MATTELIELAIETSKHAYVPYSHFPIGAVLVAKDGSVYTGVNIE
                     NASYPLTNCGERTAIFKAISEGQREFSELIVYGQTEKPISPCGACRQVMAEFFEQDLK
                     VTLVAKDKSTVEMTVGELLPYSFTDLN"
     gene            19113..20165
                     /locus_tag="ACL3EZ_001553"
     CDS             19113..20165
                     /locus_tag="ACL3EZ_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HGR0393097.1"
                     /translation="MNKKQWLGLGLVAVAAVGLAACGNRSSRNAASSSDVKTKAAIVT
                     DTGGVDDKSFNQSAWEGLQAWGKEHNLSKDNGFTYFQSTSEADYANNLQQAAGSYNLI
                     FGVGFALHNAVEEAAKEHTDLNYVLIDDVIKDQKNVASVTFADNESGYLAGVAAAKTT
                     KTKQVGFVGGIESEVISRFEAGFKAGVASVDPSIKVQVDYAGSFGDAAKGKTIAAAQY
                     AAGADIVYQVAGGTGAGVFAEAKSLNESRPENEKVWVIGVDRDQEAEGKYTSKDGKES
                     NFVLVSTLKQVGTTVKDISNKAEKGEFPGGQVIVYSLKDKGVDLAVTNLSEEGKKAVE
                     DAKAKILDGSVKVPEK"
     gene            20309..21844
                     /locus_tag="ACL3EZ_001554"
     CDS             20309..21844
                     /locus_tag="ACL3EZ_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000929819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0393098.1"
                     /translation="MAHENVIEMRDITKVFGGFVANDKINLHLRKGEIHALLGENGAG
                     KSTLMNMLAGLLEPTSGEIAVNGQVVNLDSPSKAASLGIGMVHQHFMLVEAFTVAENI
                     ILGSELTKNGVLDIAGASKEIKALSERYGLAVDPSAKVADISVGAQQRVEILKTLYRG
                     ADILIFDEPTAVLTPSEIDELMAIMKNLVKEGKSIILITHKLDEIRAVSDRVTVIRRG
                     KSIETVEIAGATNADLAEMMVGRSVSFKTEKQASKPKEVVLSIKDLVVNENRGVPAVK
                     NLSLDVRAGEIVGIAGIDGNGQSELIQAITGLRKVESGSIELKGDSIVGLHPRQITEL
                     SVGHVPEDRHRDGLILEMMISENIALQTYYKEPHSKNGILNYSNITSYAKKLMEEFDV
                     RAASELVPAAALSGGNQQKAIIAREIDRDPDLLIVSQPTRGLDVGAIEYIHKRLIEER
                     DNGKAVLVVSFELDEILNVSDRIAVIHDGKIQGIVSPETTNKQGLGVLMAGGNLGKEK
                     SDV"
     gene            21837..22895
                     /locus_tag="ACL3EZ_001555"
     CDS             21837..22895
                     /locus_tag="ACL3EZ_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0393099.1"
                     /translation="MSKKLQQISVPLISVFLGILLGAIVMWIFGYDAIWGYEELFYTA
                     FGSLRGIGEIFRAMGPLVLIGLGFAVASRAGFFNVGLPGQALAGWILSGWFALSHPDM
                     PRPLMILATIVIALIAGGIVGAIPGILRAYLGTSEVIVTIMMNYIVLYVGNAFIHAFP
                     KDFMQSTDSTIRVGANATYQTPWLAELTGNSRMNIGIFFAIIAVAVIWFMLKKTTLGF
                     EIRAVGLNPHASEYAGISAKRTIILSMIISGALAGLGGAVEGLGTFQNVYVQGSSLAI
                     GFNGMAVSLLAANSPIGILFAAFLFGVLQVGAPGMNAAQVPSELVSIVTASIIFFVSV
                     HYLIERFVKPKKQVKGGK"
     gene            22898..23854
                     /locus_tag="ACL3EZ_001556"
     CDS             22898..23854
                     /locus_tag="ACL3EZ_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0393100.1"
                     /translation="MSIITLLPLLVSSMLIYSAPLIFTSIGGVFSERGGVVNVGLEGI
                     MVMGAFSGVVFNLEFAEQFGAATPWLSLLVAGLVGSVFSIIHAAATVHFRADHVVSGT
                     VLNLMAPALAVFLVKVLYNKGQTDNLSQTFGRFDFPVLANIPVIGDIFFKSTSLLGYL
                     AIAFSFLAWFILFKTQFGLRLRSVGEHPQAADTLGINVYKMRYLGIIISGFLGGIGGA
                     IYAQSISVNFSVTTIVGPGFIALAAMIFGKWNPIGAMLSSLFFGLSQSLAVIGSQLPF
                     LQGVPAVYLQIAPYVLTILVLAAFFGKAVAPKADGINYIKSK"
     gene            23939..24236
                     /locus_tag="ACL3EZ_001557"
                     /pseudo
     CDS             23939..24236
                     /locus_tag="ACL3EZ_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT         7077 a         4355 c         5491 g         7313 t
ORIGIN      
        1 cagattgaaa taagatgaga acaaatcgat tgggaaagta aaattaattt ctataaatgt
       61 tttagcaatt gtttcgtact atttcagatt cagtctacta tatatcataa tggacaaagg
      121 gcaagctgtc aagaaattac agttatttta gtaaaaaaag aagcagaaaa atttcatttt
      181 ctactccttt tctataggat ttatttttct ttttcagaac ttttaacttc agcttttttg
      241 gcagatttaa tctgaatgtt tcccttgcta gtcataactg ctttgagatc tttttcgctt
      301 ggattttcaa ggtagtagtc agtgattgtg tcctcaatat agtcttgaat agtccgacga
      361 agtgggcgtg ctcccatttt tggatcataa cctaggtcaa ccaacttttc cttgaccttg
      421 tcagttacat ccaaacgaat gttgttgcta gagaggcgct tgttaacatc tgctagcatg
      481 agctcgacaa tctgaaggag gttatccttg ctgagagcct taaattcgat aatgccatca
      541 aaacggttca taaactctgg gctaaagaag ttaccgagtt caccgaggac agaattggta
      601 cgtccttctc tagcagcacc aaatccaacg ctagcttcgg tctttcctgt acctgcattt
      661 gaggtcatga taatgatggc atccttgaag ctaacggtgc gtccttgccc gtctgtcaaa
      721 cgaccatcgt ccaagacttg aagaaacatg tgcataacat ctgggtgagc tttttccact
      781 tcatcgagaa ggatgagaga atacggattg tggcgaactt tttcagttaa ttgaccagcc
      841 tcatcatagc caacataacc tggaggagcg ccgaccaact tagccacact atgtttttcc
      901 atgtattcac tcatatcaaa gcgaatcata ctatcagcag aaccaaaaag ttcgatagcc
      961 agttgtttgg aaagttctgt cttaccgaca ccagttggtc caacgaagag gaagcttccg
     1021 attgggcggt taggggtacc aagtccgaca cgattacggc gaatagcctt ggcaatctta
     1081 tcgactgcat catcttggcc aataacatga gacttgagat cttcggctag atggatgagt
     1141 tgagattgtt ctttctcttt caaatcacca acagggatat tggttttctg ctcgataatg
     1201 tgctcaatag ttttctcgct gatgatagga gtatcctggt ctgtgatctt tttcttttgc
     1261 atttccttat acttggcaat ctggtcgcgg aagtaggccg ccttctcaaa atcttcttct
     1321 cgtgtagctt gagacttgag attttcagcc tcaatcaagc gctgatcaat tactttagga
     1381 tccacaaaat tcaaggtcaa gttcatctta gaaccagctt catctaggag gtcaatggcc
     1441 ttgtcaggca agaagcgatc ttggatgtag cgattggaaa gagttgcagc tgcttcaatc
     1501 gcagcatcgg tatattgaac gtggtggtaa tcttcgtatt tcttttgaat ccctttgaga
     1561 atagtgattg tttcatccac cgttggttca tcgactttaa caggctgcat acgacgctcg
     1621 agggcagcat ccttttcaat gatacggtat tcattgaggg tagtagcacc gactagttgc
     1681 agttctccac gagcaagggc tggcttgagg atatttcctg cgtccatatt accatcactc
     1741 gcagaaccag caccaacaat ttcatggatt tcatcgataa agaggatgat gtcttcacgt
     1801 ttgcgaattt cttccatgag tttttgcatg cgttcttcaa attgtcctcg aatccccgtt
     1861 ccttgaacta agctaaccac atccagacgg atgacttgtt taccttggag tttatgtggc
     1921 acatcgccat cgacaatttt ctgagctaga ccttcgacaa cggccgtttt tccgacacca
     1981 ggttcaccga taaggacagg attattcttg gttctacgat tgagaatctc gatgacacgg
     2041 ataatctcat cgtcgcgccc aataacgggg tcaatgtctc cacgacgggc aatttcagtt
     2101 acattaatac caaattcttc cagcaggcct ttttcttggc taggtggcgg agtttgagca
     2161 gatccacgat tttgggaacc ataaccgccg tttccaccgt aacctccacc tgattgggtt
     2221 gggggaatag gaggagtatt gctagaaggt ctgaaattgt ttagatcatt gaagaaatca
     2281 ccaaagggat cgaagtcacg attgttcaga tccgtcatac ctttgaagag gctattgtta
     2341 ggatctgttt tgataatctt atagcagttt tgacagaggt caatttgttt ttgttttcca
     2401 ttgagattgg tgtaaagatg aattgttgag tcgttaattt tacagttttg acaaagcata
     2461 catctacctc atttctttct ttagcctgac ttgtttaaag gtcaaaaata gtcaaattct
     2521 atactctcat tataacagga ttggggtgta aagcaagtaa aaagattgaa gctttgagaa
     2581 gttgttacaa tgaaaatttt tgtgaatttg gactataaaa aaatcctatt tgtgagacaa
     2641 aaaggatttt acttagacat gcagggacaa tcccagcttg ttttagatta gtagagaagt
     2701 tcgtaaattt ccattgcgat taagtcaatg ctatcaaacg tatacgtttc gcgatcttct
     2761 acgtcacgaa gggtaaagat tgggccgttt tcttcgtcgt ggctgtacgc aacttctgca
     2821 acaacaactc cttcgcgttc aaaattacgt tttaaatttc cgccatcgtt tgccattgct
     2881 tcaaggcggt tgatgattct aaccaaatgt gattccattt tgattctcct tcatttctta
     2941 tcgttactat tttaccataa aggaggccaa cttgactaga aaaaactaag atttctcgtt
     3001 aattctgcta gtttaaagat ttttaaataa attggataaa aaatttaaat tttaattcaa
     3061 aacatgttat aatcatacag tattctattt tagaaagcag tgtgactatg aatttttctt
     3121 ttttacctaa gtatttacct tattttaact atggggctgt tgtgacgatt cttatttcta
     3181 tctgtgttat ctttttggga actattttgg gtgttgtctt ggcttttggg caacgttcaa
     3241 agtttaaacc gcttgtttgg ttggccaact tgtacgtttg gattttccgt gggacaccga
     3301 tgatggttca aattatgatt gcctttgctc ttatgcatat caatgctccg actattcaga
     3361 ttggaatttt aggtgttgat ttttcgcgtc tgattccagg gattttgatt atctctatga
     3421 atagtggtgc ttatgtttcg gagactgttc gtgccggaat caatgcggtt ccaaaaggtc
     3481 agctagaggc ggcttattcg ctagggattc gtcctaaaaa tgcgatgcgt tatgtgattt
     3541 tgccacaagc agtcaaaaat atcttgccag cattggggaa cgaatttatc accattatca
     3601 aggacagctc cctcttatca gctattgggg tcatggagtt gtggaatggg gctacaacag
     3661 tttctacaac aacctatcta cctttaacac cacttttatt tgcagcattt tactacttga
     3721 ttatgacctc tattctgaca gtagccttga aagcttttga aaaacatatg ggacaaggag
     3781 ataagaaata atgacagaaa ccttgataaa aattgaaaat ttacataaat cttttggaaa
     3841 gaatgaagta ttgaagggca tcaacctcga gattaaaaga ggagaagttg tcgttatcat
     3901 cggtccttca gggagtggga aatctacctt gcttcgctct atgaatttgt tggaggaagc
     3961 aaccaagggg aaggttatct ttgagggagt cgatattacg gacaagaaga atgacctgtt
     4021 tgccatgcgt gagaagatgg gcatggtttt ccaacaattt aacctctttc ctaatatgac
     4081 tgtgatggaa aatattacct tgtcacctat caagactaaa ggtgaaagca ggaaagttgc
     4141 tgagaagaga gcccaagagc ttttggaaaa agttggtttg ccagataagg cagacgctta
     4201 tccacagagt ctgtcgggtg ggcaacaaca acggattgcc atcgcgcgtg ggttggctat
     4261 ggaaccagat gttttgctct ttgacgaacc aacttcagcc ttggatcctg aaatggtagg
     4321 tgaggtattg gctgttatgc aagaccttgc caagtcaggg atgactatgg ttatcgtaac
     4381 acatgagatg ggatttgccc gtgaggtggc agatcgtgtt atctttatgg cagacggtgt
     4441 ggttgttgaa gatgggacac ctgagcagat ttttgaacaa acccaagaac aacggactaa
     4501 agatttcttg agtaaggttt tataatctat tttaaaattt caagacaaga ttagtgaaaa
     4561 gttcaaccag agctttttct tatagtttga aactatagga taacctagga aagaagtgtt
     4621 agagggcact agcagttttt ggtataatgg aagatatttg aaagaaaaga gaagtgatat
     4681 gacacagatt attgatggga aagctttagc ggccaaattg caggggcagt tggctgaaaa
     4741 gactgcaaaa ttaaaggaag aaacagctct agtgcctggt ttggtagtga ttttggttgg
     4801 ggataatcca gccagccaag tctacgttcg caacaaggag aggtcagctc ttgcggctgg
     4861 ttcccgtagc gaagtagtgc gagttccaga gaccattact caagaggaat tgttagacct
     4921 gattgctaaa tataatcagg atccagcttg gcatgggatt ttggtccagt tgccattacc
     4981 aaaacatatc gatgaagagg cggttttatt agccattgac ccagaaaagg atgtggatgg
     5041 tttccatccc ttaaacatgg gacgtctttg gtctggacat ccagtcatga ttccctcgac
     5101 acctgcagga attatggaaa tgtttcatga atatgggatt gacttggaag gtaaaaatgc
     5161 ggtcgtcatc ggtcgttcaa atatcgttgg aaaacctatg gctcagcttc ttttggctaa
     5221 aaatgcgaca gtaaccttga cccactcacg aactcataat cttgccaagg tggctgctaa
     5281 agcagatatt cttgtagtcg caatcggccg cgccaagttt gtgactgctg actttgtcaa
     5341 accaggtgcg gttgtcattg acgttgggat gaaccgagat gaaaatggga agctctgtgg
     5401 agatgttgat tatgaggcag ttgcaccact tgctagctat atcacgccag tccctggagg
     5461 tgtcggtcct atgaccatta ccatgctgat ggagcaaact tatcaagcag cacttcggac
     5521 attggataga aaataagaga aacattcgat taatagagtg tattttctat agctatatct
     5581 aaaatggcag aaatgaatat taaattttag atataagatt acaaaaggag gtctgcgtct
     5641 cctttttatt gtataataaa agtgagagga aaaaaggatg aaagtgatta atcaaacctt
     5701 attagaaaaa gttattattg aacgttctcg ttcaagtcat aaaggagatt atggtcgtct
     5761 gctgctgctt ggtggtactt atccttatgg aggtgccatc atcatggctg ctttagcagc
     5821 tgtaaaaagc ggtgcaggat tggtgaccgt tggaacggac agggaaaata tcccggctct
     5881 gcacagccat ttacctgagc ctatggcctt ttctcttcaa gaccagcaat tgttaaaaga
     5941 gcaattggag aaggcagaag ttgtcttgtt ggggcctggt ttacgagacg atgcttctgg
     6001 agaaaatcta gtaaaacagg tctttgttaa tttaagccaa aatcagattt tgattgtaga
     6061 cggaggtgcc ttgaccattc ttgctaggac aagtttgtca tttccctcaa gccagcttat
     6121 cctaactcct caccaaaaag aatgggaaaa attatctgga attacgattg aaaagcaaaa
     6181 ggaagatgca acggctagtg ttctgacttc cttccctcaa ggaacaattt tggtggagaa
     6241 aggcccagct actcgtattt gggaagttgg ccaatctgat tattaccagt tacaggttgg
     6301 tggtccttat caggcgactg ggggaatggg agatactctg gctgggatga tcgcaggatt
     6361 tgtaggccaa ttccgacagg ccagtctcta cgagcgtgtg gcagtagcga cccatcttca
     6421 ttcagccata gcccaagaac tatctcagga aaattatgtg gtcttaccga cggaaatcag
     6481 caggtatctt cccaaaataa tgaaaattat ttgtcaacaa gagagggtaa gcaaagataa
     6541 acttgtttaa aatagacaga taaatctact tccttctctt aatttatgat tcttgaaatg
     6601 cgcctgcttt aaggctaaac tagacgtatc aaagttaaga gtttgttttt gtaactggaa
     6661 agagatgaac aaatcaaata cataaaagat aaactcattt ttattcgttt ggtaaaaata
     6721 aaatgcatat ttttaaagaa agattgatga aaaatgtaga tttgatgttt ttacttgaat
     6781 aaaaagcggt ttcatagtaa aataagaact gagaatgatg gaggtaaatc ggtggaaaat
     6841 ctgaagaaaa tggcaggtat caaggctgct gagttcgtga gcgatggaat ggtcgttgga
     6901 cttggaacag gctcgactgc ctattatttt gtcgaagaaa tcggtcgtcg tatcaaggaa
     6961 gaaggattgc agattacagc tgtaacaact tctagtgtga ccactaaaca ggcagaaggc
     7021 cttaatatcc cgctcaagtc tattgaccaa gtagactttg tcgatgtgac ggttgatggc
     7081 gcggatgaag tggatagtca gtttaatgga atcaaaggcg gtggtggtgc ccttctcatg
     7141 gaaaaggtgg tcgcaacacc atcaaaagaa tacatttggg tggtggatga aagcaagctg
     7201 gtcgaaaaac taggtgcttt taaattgcca gtagaagtgg ttcagtatgg tgcagagcag
     7261 gtctttcgtc attttgaacg agctggctac aaaccaagtt tccgtgaaaa agacggccaa
     7321 cgttttgtga cggatatgca gaattttatc attgacctcg ccttggatgt cattgaaaat
     7381 ccaattgctt ttggacaaga attggaccat gtcgttggtg ttgtggagca tggtttattc
     7441 aaccaaatgg tggataaggt aatcgttgct ggacgagatg gagttcagat ttcaacttca
     7501 aaaaaaggaa aatagaaggg ggcataagat gtctaaattt aatcgtattc atttggtggt
     7561 actggattct gtaggaatcg gtgcagcacc agatgctaat aactttgtca atgcaggggt
     7621 tccagatgga gcttctgaca cactgggaca catttcaaaa acagttggtt tgaatgtccc
     7681 aaacatggct aaaataggtc ttggaaatat tcctcgtgaa actcctctta agactgtagc
     7741 agctgaaatc aatccaactg gatatgcaac aaaattagag gaagtatctc ttggtaagga
     7801 tactatgact ggacactggg aaatcatggg actcaacatt actgagcctt tcgatacttt
     7861 ctggaacgga ttcccagaag aaatcctgac aaaaatcgaa gaattctcag gacgcaaggt
     7921 tattcgtgaa gccaacaaac cttattcagg aacggctgtt atcgatgatt ttggaccacg
     7981 tcagatggaa actggagagt tgattatcta tacttcagct gaccctgttt tgcagattgc
     8041 tgcccacgaa gacattattc ctttggatga attgtaccgt atctgtgaat acgctcgttc
     8101 gattaccctt gagcgtcctg cccttcttgg tcgcatcatt gctcgccctt atgtaggtga
     8161 accaggtaac ttcactcgta cggcaaaccg tcgtgacttg gctgtatctc cattttcccc
     8221 aactgttttg gataaattga atgaggctgg tatcgatact tatgctgtgg gtaaaatcaa
     8281 cgatatcttt aacggtgctg gtatcaacca tgacatgggt cacaacaagt caaatagtca
     8341 tggaattgat acactattga agactatggg acttgctgag tttgaaaaag gattctcatt
     8401 cacaaaccta gttgactttg atgcccttta cggccatcgt cgtaatgctc acggttaccg
     8461 tgattgtttg catgagtttg atgaacgctt acctgaaatt atcgcagcta tgagagagaa
     8521 tgaccttctc ttgattactg cggaccatgg aaatgaccca acgtatgcag ggacggatca
     8581 cactcgggaa tatattccat tgttggcata tagccctgcc tttaaaggaa atggtctcat
     8641 tccagtagga cattttgcag atatttcagc gactgttgcc gataactttg gtgtggaaac
     8701 tgctatgatt ggggaaagtt tcttagataa attggtataa gatgacgcgc tatgctttgc
     8761 tggtgagagg tatcaatgtt ggtagtaaga ataaggtcgt tatggcggag cttcgtcaag
     8821 aattgacaaa cttgggactg gaaaaggttg agagctacat caacagtggc aatattttct
     8881 ttacttcgat agattccaaa gcccaattgg tttaaaagct agagactttc tttgcagtcc
     8941 attatccatt tattcagagc ttttctttac tgagtctaga ggactttgag gcggaacttg
     9001 aaaatctacc agcttggtgg agcagagact tggcacgaaa agattttctc ttttacactg
     9061 agggtttgga tgtggaccaa gtcatcgcga cagttgaaag tttagagctg aaagatgaag
     9121 tgctttattt tagaaaactt gggattttct gggggaaatt ttctgaagaa tcctattcta
     9181 agactgccta tcataagtac ttgctgaagg tgcctttcta ccgccacatt actattcgta
     9241 atgctaaaac ctttgacaaa attggtcaaa tgctaaaaaa taataaagga gacacataat
     9301 gacattttta aacaaaatcc atgaaactgc tactttcctg aaagaaaagg gaattgcagc
     9361 ccctgagttc ggtctaatcc ttgggtcagg acttggagaa ttggcagaag aaatcgaaaa
     9421 tccagttgta gtagactatg ctgagattcc aaactggggc cgttcaacag tagtcggtca
     9481 tgctggtaaa ttggtatatg gtgaactggc aggtcgcaag gtcttggctc ttcaagggcg
     9541 tttccatttc tatgaaggga atcctctgga agtggtgact ttcccagttc gtgtgatgaa
     9601 agttcttgga tgtgaaggtg ttattgtaac caatgcagct ggcggtatcg gatttggtcc
     9661 tggtaccttg atggctatct cagaccatat caacatgacg gggcaaaatc cattgatggg
     9721 tgaaaacttg gatgactttg gcccacgttt cccagatatg tctagggcct acacaccaga
     9781 ataccgtgcc actgcccatg aagtggctaa aaaacttaat atcaagcttg atgaaggtgt
     9841 ctatatcgga gttactggtc cgacttatga aacaccagca gaaattcgtt cctataagac
     9901 actgggagca gatgcagttg gtatgtctac ggttcctgaa gttatcgtgg cggcccactc
     9961 tggcttgaaa gttctgggaa tttcatgtat cactaacttt gcggccggtt tccaagaaga
    10021 actcaatcac gaagaagttg tagaagtgac tgaacgtgtt aaaggtgatt tcaaaggctt
    10081 gcttaaagcg attcttgctg aattgtaaga aaaaagattt aaaaggggaa gtacctctgt
    10141 tttttcagga ttgactgcct atccggatta aagaagaaac agaggaatac tatgagcttc
    10201 ttcctgctct tataactgaa agaagcggaa gaataggtat gtctgatctg atagccagca
    10261 ttgtgaaaga caagattcta ggatactagc attagcttcc tagccaagca gactagtatg
    10321 ataaggagag atgagaatga attgactttc tgaatttctc agtcttatca tatatagcac
    10381 aatgagattt cgcttgagtc tgcttgtaaa taaacgaaaa gaaagataag aaataatgaa
    10441 aattggtcaa cgaattatgc gctttggcat aaaaaattaa gtatcggagt tgtatctgtt
    10501 gtagtcggct ttgatttcta gctccagctg gaatttcagc caatgaagta aagtaagatg
    10561 taacatctga agtggtaata ggtgtgttag attctaagga ggaattgaaa gagtcagaaa
    10621 atgatgctct aaaactagaa actcctctta gagaggagcc aagactagct cctcaaacgc
    10681 ttccggaagc aagtgaagtt agttcttgaa aacaaaaggg aagagtcaaa agtagagata
    10741 acagaaccag ctcaagcgga tgatatccgc aaggttgttg gggaattagc caaggatata
    10801 agtattacta agttgtatat gacaggtcat tttcttggat gttacctagc tcagattgca
    10861 gcggttgaag cttaccaaaa atatcctgat ttttataacc atgtattgag gagagtgaca
    10921 actttcagtg ctcctaaagt gattacttcc agaactgttt ggaatgctaa gaatggtttc
    10981 tgggatgttg gtttggaaag tcgtaaatta gctgttagtg gaaaaattaa gcattatgtg
    11041 gttgataatg acaatgttgt gactcccttg attcataatg atcgtgatat tgttacattt
    11101 acaggtaatt cacgctttaa acaccgttct cgtggctatt ttgaaagtcc aatgaatgat
    11161 attcctaact ttaatattgg taaacaagct acctttgata aacatggtta tcgtgatccg
    11221 aaattggata aagtgcgatt ctttaagaaa caggctctac ctcaatcttc tagtcaacca
    11281 agcgctgaac caatggaaaa tattgcctta ggaaaacagg ttactcaaag ttcgacagct
    11341 ttcggaggag atgctagaag agctgtggat ggcaaagtcg atggtaacta tggtcacaat
    11401 tctgtcactc atacaaactt ccaatctaag ccttggtggc aagtagattt ggctaaagaa
    11461 gaaaccattc gccaaatcaa tatttacaac cgaacagaca ctgcccagga tagattggca
    11521 aactttgatg tcattctttt agacagttct ggtaaagaaa ttgagtgaaa acgtataaca
    11581 tctcctaaag atgtgtcagc acaaattacg attaaccata aaaaaagcgc gctatgttcg
    11641 gattgagcta gaaggctata atgccctcag tcttgcagaa gttgaagttt tccgctttat
    11701 agctacgaat ggtgaaacgg cgatacaagt ttctaagtca gttcaaccaa tcagtcagac
    11761 tcctgtgaaa gataaaacat tgacaattca acacagtgga gcttacattg cccgctactc
    11821 cataacttgg gaagaagtta cagtagataa agatggaaac caagttgttc gtagtcattc
    11881 ttgggaagga aacggtcgca accagactgc aggttttgtc ctcaacctcc caatcaaaga
    11941 aaatatgaga aatctgcgag ttaagattga gaaaaagacg ggcctactat ggaatagatg
    12001 gcaaacaatc tatgaaaaca gaccaatttt agctcaaccc caccgtaaaa ttacccattg
    12061 gggtacgaca ttgaattcca aggtgagtga cgatgatgtc ttgtaatctg atggtagaat
    12121 gacagttagt ttgtctagtt tataagaaag tactacctga gcttgaatag aactcaggta
    12181 gctctctatg aaagaacaaa attaatactc aatgaaaatc aaagagcaaa ctaggaaact
    12241 agccgcaggt tgctcaaagc actactttga ggttgtagat aagactgacg aagtcagtca
    12301 catatataat ccaaggcgac gttgacgtgg tttgaagaga ttttagaaga gtataaacag
    12361 aaaggtagag cgcgtgttct aatttgaaca cgagtagaaa acttttctaa aaacaaaaac
    12421 gaaaggatgg gtaaactgta ttcgctgaac tgaatacggg cgactctcct ctaaatcaaa
    12481 attaagaaag gaattgaccc caccctaaaa gtagtgggaa aaagatagtt ggtctagcga
    12541 gcatcgctca ctgcgcccaa ctcctatttt cccttcgctt tttgatgggt ttggtatctt
    12601 tctcaatata aaatataaaa taaagaaagg tagagcgcgt gttctaattt gaacacgagc
    12661 ggaaaactcg gaaaatagat aatctgactg aaaaatcagg atttctcgtc aggttcctaa
    12721 ttttcagtcg ttttcttctc gctctttgta tcataaatta tgtctatcca tattgctgct
    12781 cagcagggtg aaattgctga taaaattctt cttcctgggg atcctcttcg tgctaagttt
    12841 attgcggaga atttccttga tgatgctgtt tgttttaacg aagtgcgtaa catgtttggt
    12901 tacactggta cttacaaggg tcactgtgta tctgtcatgg gaactgggat gggaatgcca
    12961 tctatttcga tttatgcgcg tgagttaatc gtagactacg gtgtgaagaa attgattcgt
    13021 gtgggaactg caggttcttt gaatgaagag gttcatgttc gtgaattagt tttggcgcag
    13081 gcggctgcaa ccaactcaaa catcgttcgt aatgactggc cacagtacga ttttccacaa
    13141 attgctagct ttgatttgct tgataaagcc taccatatcg ccaaaaaatt tggtatgact
    13201 actcacgttg ggaacgtttt gtcatctgat gtcttttact caaattactt tgaaaagaat
    13261 atcgagcttg gtaaatgggg agtcaaggct gtggaaatgg aagcagcagc tctttactat
    13321 cttgctgccc aataccatgt tgatgcgcta gctatcatga ccatctctga tagcttggtc
    13381 aatccagacg aagacacaac tgcagaagaa cgtcaaaata ccttcactga tatgatgaag
    13441 gttggtttgg aaaccttgat tgcagaataa ttatagccaa aaaggaagcc ctttatgaat
    13501 tgtaggactt ccttttctta tccagaaatt gatctagttc tctctgattt cgaagaatag
    13561 tgactttatg tgaatattct tggcaaagtt tttggtaatt ttctttttga gttttgctac
    13621 gcccatccca aagaatccat ctgataaact cccactcaaa gcgttcaggg caatctgccg
    13681 ccatactttc tctgactttt ccacggtatt taagataacg cttaaaggct ctaaagagac
    13741 aggtcaatgg caaaaaattg agaaagatga tttggtcagc ttcttgcatt cgttcttggt
    13801 agtagcacca agaataatta ccatcgatga cccaagcttt atgcttggtg agaaagtttt
    13861 ttatctcggt taacatccat tcgcagtcac tgtcttgcca accaggttga aattggagtg
    13921 tgtccatgtg cagttttgga atggagtagt agttagataa cttttctgct agagttgact
    13981 taccagaacc agaatatccg ataattgtga ttttcatttt ctaccttttc ctatttggag
    14041 acaaaaaaac agcctctatg gactgtttct tatttagcaa gtttagctga aagacgagct
    14101 ttatcgcggc ttgctttgtt tttgtgaatc aaacctttag tttctgcttt atcgatagct
    14161 gagctagcag cacggaaaag ttcttcagat gggtttgctt caaaagcttt tatagcagta
    14221 cgcatagctg atttttgagc tgagttcttt tcgttttgtt taacgttcaa ttcagcgcgt
    14281 ttgatagctg atttaatgtt tgccaatgtt cttacctcca tatttactaa ctataccatt
    14341 atatatgaaa acttacgttt tgacaaggga aaattatttt tttaagtaaa tttcatcgat
    14401 ttcatggttc ttgcttttat gaagaatcac ttctgcacga tttctggttg gttcaatata
    14461 attttgtaga tttgtgagat tgatactggt ccagacctga tgggcaaagg cttccacttc
    14521 cccaatcggc atctgagtaa aacgataata gtagctatca gggtcgtttt gggctagact
    14581 cagcattttc aagaaacggt ccagatacca actttcaata tcatccactc cagcatctac
    14641 atagatggaa aagtcaaaga agtcagtgat atagagacga ttgttttgtg gattttgaaa
    14701 gacattgatt ccctcaacaa ttacaaaatc agcagctttg acactttgtt tctcttcggg
    14761 tacgatgtcg taaacttcat gagaatagac aggaatatct acatcttgtc catttttgat
    14821 gcggtccaag aagttgagaa gagcttccat atcatagctt tcaggaaatc ctttacgatt
    14881 taaaatcccc tgctcaatca aggtttgatt gggatagaga aaaccatcag ttgtaaccaa
    14941 ctcaaccgta gcatctgtaa acgtacggga cagtaggatt tgaagtaggc gactggttgt
    15001 ggattttcca acggcaacac tcccagaaac cccaataata aaaggttgag atttactttc
    15061 acgttggagg aaaattcctt ttgaaaaggc taaatcttcc ttagttcgct tgtaaatctg
    15121 aatcagatga gccaagggga gatagatatc tgtaacgtct tggagactga tttggtcatt
    15181 aaaactcttg atagattcca attcttcttc tgtcaaagga ggtgttgtct ttcgatgtaa
    15241 agattgccaa gtctggcggc tgattttttc aaaatgtaaa aattcgttgg tcatttgttt
    15301 tcccctagat attttgtcta tcataccata aaaatctaaa aaaataaagc ggtttcttga
    15361 atgtggtaag tcaatggtat atagtataag tgatcaattt attgatgaaa taggagatag
    15421 attctactga tttataagtt tataagctta taaagggggc tttttagttc acaacttata
    15481 ggaggtgtac tatgaaaatc ttaaaacgtt acatattgga actctgtttt attttaagtt
    15541 ttgctttacc ttttataaaa ggagccaatg cagataatgg tatatgcttt gtggaaacct
    15601 attacggttt tacttttttg atggaacatg ctattgtaac agctgtcttt atctattcgt
    15661 tttcaattgc tttcttacta aaaaaacgat gggcgaaatg gattgctgct ggtagttatt
    15721 gctttttagt cctatggatt gcgacagagg gttatttctt ccgcatgtca ctagaagatt
    15781 tgatacgact ttggacaagt ttggaaatcc tgacacaaac gtatcagttg ggcttttatc
    15841 taaacatttt gttgggaatt ttgttgataa taaagtattt taaggttaag caatagaaat
    15901 aataatctgc ctgattatag atgataaact ttttgttttt atctggactg tgatatttat
    15961 agttctaaat ggtttattat ttataagtgt tgaaagagat tgaagaaaat ggcttcgtga
    16021 ctcgctttct tcggtctttt tcgttttatt atcaatttgt aaacgattta caatttgagt
    16081 caaattatgg taaaatagtg tcatgagtaa aatgtattat gcagaaaatc ctgacgctgc
    16141 tcacgacatt catgagttga gagtagagtt gttgggacaa aaaatgacct ttttaacgga
    16201 tgcgggtgtt tttagcaaga aaatagttga ctttggaagt caactattgc tcaagtgtct
    16261 tgaggtcaac caaggagaaa ctgtccttga tgtaggctgt ggttacggac ctttgggttt
    16321 gtccttagct aaggcttatg gagttcaggc tactatggtt gatatcaaca ctcgtgcctt
    16381 agatttagct cggagaaatg ctgaaaaaaa taatgcaaaa gcgacgattt tccagtccaa
    16441 catctatgaa caagttgaag gacattttga tcatgtcatt tccaatcctc ctatccgtgc
    16501 gggcaagcaa gtcgttcatg aaatcattga gaaaagtaaa gatttcttgg aaactagtgg
    16561 ggatttgaca atcgtcatcc agaaaaaaca aggggctcca agtgctaagt ccaagatgga
    16621 gggtgtgttt ggtaattgtg aaatccttaa aaaagacaag ggatactata tccttagaag
    16681 tgtgaaagaa tgagagcagt tgatttaata caaaaaaaac gagacggtca agaactgact
    16741 tcaagtgaaa ttgaatggct ggtagaaggc tatgtgtcag gaactgttcc tgattatcag
    16801 atgtctgcct ttgctatggc tgtttatttt aaaggaatga cgactcgaga aatctctgat
    16861 ttaacgatga atatggttaa gactgggcaa gagtttgacc tgtcagccat tgatggtgtg
    16921 aaagttgaca agcattctac tggtggtgtc ggcgataagg taaccttgat tttagttcct
    16981 cttgttgcta gcttcggtgt gcctgtagca aaaatgagtg gtcgtggtct tggccataca
    17041 ggcggaacaa ttgataaatt ggagtccatt aagggctatc aagtagaacg tagtcaagag
    17101 gattttattc gtcaggttca ggatattgga gtatctgtca ttgggcaatc agaccagctg
    17161 gtcaaagcag ataagcttct ctatgccctt cgtgatgtga ccgcaactgt cgacacgatt
    17221 cctttgattg cgagttcggt gatgagcaag aaaattgcgg caggggcgga tgctattttg
    17281 ctagacgtga ctgtcggtga gggtgccttc atgaagacgg ttgatgaggc gcgtgagttg
    17341 gctcaaacta tggtagatct tggtaaggtt gttggacgga agacagtagc agtgattacg
    17401 gatatgagcc agcctttggg acgagcgatt ggaaatcgtc tggaaatcct tgaagcattg
    17461 gagattttgc aaggtcaagg acgtcaggat attacccact ttatttgtga attggctcaa
    17521 attatgcttg gtttggcaaa tgttaacaaa actgttgaag aagttcgcca acatcttgag
    17581 aatggtcaag cactggctaa gtttgaggaa atggtgcaag cccaaggtgg agacttggaa
    17641 gacctctatc gtcctgtaaa tgtagctcat gtggtggaaa tccctgctca ggaaacgggt
    17701 gtcatttcag ctcttccagc tatggacttt ggtctttatg ccatgaggct gggtgctggt
    17761 cgtgcagtta agtctgatgc cttggactat gaaacaggaa ttgtttttga aaagaagatt
    17821 ggagactccg ttcaaaaggg tgaaattgtt gcaaaagtat acacaaatga aaaaattcca
    17881 cctcaactag ttacagattt ccaaaaatgt gttaaaataa gtgatgaagt aaaaaaaatc
    17941 cgtgaaattg tagaaatcat ctcctaaatg gagggaaaac cgaaatgaaa ttaaataaat
    18001 atatagatca tacgctttta aaacaagatg caaagaaaaa acaaattgat agtttgttgt
    18061 ctgaggctag agagtatggc tttgccagtg tttgcgttaa tccgacctgg gttgaacatg
    18121 ctaaaaaagg acttgaaggc acagatgtta aggtttgcac agtagtaggt ttccctttgg
    18181 gagcaacaac ttcagccgtg aaagcatttg agacaaaaga agctatccaa aatggtgcag
    18241 atgagattga tatggtgatc aatgttggag ctctcaaatc aggtaattta gccttggttg
    18301 agtcagatat tcgcgcagta gtggaagcaa gtggtgataa gttagtgaaa gtcattattg
    18361 aagcttgcct tctgacagac caagaaaaaa ttgttgtttg ccaattggcc caaaaagctg
    18421 gggctgactt tgttaaaaca tctactggtt tttcaactgg tggtgctacg atagcagatg
    18481 ttacattaat gcgtgaaaca gttggatctg atatgggagt caaggctgct ggtggagctc
    18541 gttcttatgc agatgctctt gcctttgtcg aagcaggtgc gacccgtatc ggaacgtcag
    18601 ctggggtagc tattttaaaa ggagaattgg cagatggcga ctactgagtt gattgaactg
    18661 gcaattgaaa ccagcaaaca tgcctatgtc ccctattctc actttcctat cggagcagtt
    18721 ttagtagcca aagacggaag tgtttacacg ggagtgaata tcgaaaatgc tagctatcct
    18781 ttgaccaatt gcggtgagag aacagctatt tttaaggcta tatctgaagg ccaaagagaa
    18841 ttttcagaat tgattgtcta tggtcaaact gaaaaaccga tctcgccatg tggtgcttgt
    18901 cgccaagtga tggctgaatt ttttgaacaa gatctaaaag tgaccttagt cgcaaaagat
    18961 aaatcgacgg tcgagatgac ggtcggggaa ttacttccat actcttttac agacttaaac
    19021 tagtctgagt cgctctctga gtggcacggt ccttgtggcc aaccaatcca tacttgcaac
    19081 atcgttgcac atcttattta ggaggttcag taatgaacaa gaaacaatgg ctaggtcttg
    19141 gcctagttgc agtggcagca gttggacttg ctgcatgtgg taaccgctct tctcgtaacg
    19201 cagcttcatc ttctgatgtg aagacaaaag cagcaatcgt cactgatact ggtggtgttg
    19261 atgacaaatc attcaaccaa tcagcttggg aaggtttgca ggcttggggt aaagaacaca
    19321 atctttcaaa agataacggt ttcacttact tccaatcaac aagtgaagct gactacgcta
    19381 acaacttgca acaagcggct ggaagttaca acctaatctt tggtgttggt tttgcccttc
    19441 ataatgcagt tgaagaagca gctaaagaac acactgactt gaactatgtc ttgattgatg
    19501 atgtgattaa agaccaaaag aatgttgcga gcgtaacttt cgctgataat gagtcaggtt
    19561 accttgcagg tgtggctgca gcaaaaacaa ctaagacaaa acaagttggt tttgtaggtg
    19621 gtatcgaatc tgaagttatc tctcgttttg aagcaggatt caaggctggt gttgcgtcag
    19681 tagacccttc tatcaaagtc caagttgact acgctggttc atttggtgat gcagctaaag
    19741 gtaaaacaat tgcagccgca caatacgcag ccggtgcaga tattgtttac caagtagctg
    19801 gtggtacagg tgcaggtgtc tttgcagagg caaaatctct caacgaaagc cgtcctgaaa
    19861 atgaaaaagt ttgggttatc ggtgttgacc gtgaccaaga agcagaaggt aaatacactt
    19921 ctaaagatgg caaagaatca aactttgttc ttgtatctac tttgaaacaa gttggtacaa
    19981 ctgtaaaaga tatttctaac aaggcagaaa aaggagaatt ccctggcggt caagtgatcg
    20041 tttactcatt gaaggataaa ggggttgact tggcagtaac aaacctttca gaagaaggta
    20101 aaaaagctgt cgaagatgca aaagctaaaa tccttgatgg aagcgtaaaa gttcctgaaa
    20161 aataatggat ggaagtcatt tcttaggaag cggccaaggg ccgctttttt aagagttgag
    20221 acaaagtcat tttgtctcag taaagcttgc tactagacaa actagcaagt tttattgaaa
    20281 taaaataaga ctctgaaagg aagagcacat ggcacacgaa aatgtcattg agatgcgtga
    20341 tattaccaag gtgtttggtg gatttgttgc caacgacaaa atcaacttgc acctacgaaa
    20401 aggtgaaatt catgcacttt taggagaaaa tggggctggt aagtccacgc taatgaacat
    20461 gttagcaggc cttcttgaac caactagtgg tgaaatcgcg gtcaacggtc aagttgtcaa
    20521 tctcgactcc ccatctaaag cagctagctt gggaatcggg atggttcacc agcactttat
    20581 gttggttgaa gccttcacag tggctgaaaa catcatttta ggtagtgaat tgactaaaaa
    20641 tggtgtgcta gatatcgctg gagctagcaa agaaatcaag gctctttctg aacgttatgg
    20701 cttagctgtt gacccttctg ccaaggtagc agatatctca gttggagccc aacaacgtgt
    20761 agaaatttta aaaacacttt atcggggggc tgatatcctt atctttgacg aaccaacggc
    20821 tgttttgact ccatcagaaa ttgatgagtt gatggctatt atgaaaaatc ttgtcaaaga
    20881 aggaaaatca attatcttga ttacccacaa attggatgaa attcgcgcag tttctgaccg
    20941 tgttacagtt atccgtcgtg ggaaatcaat tgaaaccgtt gaaattgcag gggctaccaa
    21001 tgctgatttg gcggaaatga tggtaggacg ttctgtttcc tttaaaacag agaagcaagc
    21061 ctctaaacca aaagaagtgg ttttgtctat caaagatttg gtggtcaatg aaaaccgtgg
    21121 tgttccagct gttaaaaatc tgtccttgga tgttcgtgct ggagagattg ttggtattgc
    21181 ggggattgat ggaaatggtc agtctgaact gattcaagcc attacaggtc ttcgtaaggt
    21241 tgaatctggt agcattgagc taaaaggaga ttcaattgta ggcttgcacc cacgtcagat
    21301 tacagaacta agtgttgggc acgttccaga agaccgtcac cgtgatggct tgattttgga
    21361 aatgatgata tctgaaaata ttgcccttca aacctactat aaagaaccac atagtaaaaa
    21421 tggaattttg aattattcaa atattacttc ttatgctaaa aagctgatgg aagagtttga
    21481 tgttcgcgct gccagtgaat tagttcctgc agctgcactc tcaggaggaa atcaacaaaa
    21541 agcaattatt gctcgtgaaa ttgatcgaga tcctgatctc cttatcgtta gccagccaac
    21601 tcgtgggttg gatgtcggtg ccattgagta tatccacaaa cgcttgattg aagagcgtga
    21661 taatggcaag gctgtccttg ttgtcagctt tgaattggat gagattttaa acgtctcaga
    21721 ccgtattgcc gttatccacg atggtaagat tcaaggtatt gtatcaccag aaacaaccaa
    21781 taaacaagga cttggtgtct tgatggctgg tggaaacttg ggaaaggaga agagtgatgt
    21841 ctaaaaaatt acaacaaatt tcggttccct tgatttctgt attcctagga attttactcg
    21901 gagccattgt catgtggatc ttcggttatg atgctatttg gggctacgaa gaattgttct
    21961 atacagcctt tggcagtctg cgtgggattg gagaaatctt ccgtgctatg ggtcctctgg
    22021 tcttgattgg tcttggtttt gcggttgcca gtcgagctgg tttctttaac gtcggacttc
    22081 ctggtcaggc tttggcaggt tggattctca gtggttggtt tgccctgtcg catccagata
    22141 tgccccgtcc cttgatgatt ctagcaacca tcgtgattgc cttgattgct ggtgggattg
    22201 tcggagcgat tccaggtatt cttagggcct atctagggac gtcagaggtt attgtaacca
    22261 tcatgatgaa ctacattgtc ttgtatgtag ggaatgcctt tatccatgct ttccctaaag
    22321 acttcatgca aagtacagat tcgaccattc gtgttggggc taatgcaacc tatcagacac
    22381 cttggttggc tgagttgact ggtaactcac ggatgaatat tggtattttc tttgccatca
    22441 ttgccgttgc agttatttgg ttcatgctca agaaaacaac tcttggtttt gaaatccgtg
    22501 cagttggtct taatccacat gcttcagaat atgctggtat ttctgccaag cggactatta
    22561 tcctatctat gattatttca ggtgccttgg caggtcttgg tggagctgtt gaaggtttgg
    22621 gaaccttcca gaacgtctat gttcaaggtt cgtcattagc tatcggattt aacggaatgg
    22681 cggttagttt gcttgcggcc aactcaccaa ttggtatact ctttgcagcc ttcctatttg
    22741 gcgttctcca agttggggct cctggtatga atgcggcgca ggtaccatct gagcttgtca
    22801 gcattgtaac agcgtctatt atcttctttg tcagtgttca ttaccttatc gaacgctttg
    22861 ttaaaccgaa aaaacaagtt aaaggaggta agtaaagatg tctattataa ccttgctccc
    22921 cctcttggtg tcttctatgc tgatttactc agcacctctc atctttacaa gtatcggtgg
    22981 tgttttctct gaacgtggtg gtgtggtaaa cgttggcctt gaaggaatta tggttatggg
    23041 tgccttttct ggagttgtct ttaaccttga atttgcagaa caatttggag cagcaactcc
    23101 atggctatcc ttgcttgtag caggattggt tggtagtgtt ttctctatca tccacgcagc
    23161 agcgacggtt catttccgtg cagaccatgt tgtcagcggt acggtattga acttgatggc
    23221 gcctgccttg gctgttttct tagttaaagt tctttataac aaaggacaaa ccgacaacct
    23281 aagtcaaact tttggacgct ttgatttccc agtcttggca aatatcccag tgattggtga
    23341 tatcttcttc aagtcaacta gtctacttgg ttatctggcg attgccttct cattccttgc
    23401 ttggtttatt ctctttaaga ctcaatttgg tcttcgtctc cgctctgtcg gtgaacatcc
    23461 tcaagcagcg gataccttgg gaatcaacgt ctacaagatg agatatttag ggattattat
    23521 ttcaggtttt ctaggtggaa ttggcggagc gatttatgcg caatcaatct cagttaactt
    23581 ctcagtgaca actattgttg gacctggatt tatcgccctt gctgcgatga tctttgggaa
    23641 atggaatcca atcggtgcta tgctttctag tctcttcttt ggactttcac aaagtttggc
    23701 tgttatcggt tctcaattgc cgttcctaca aggagtgcca gcggtttatc ttcaaattgc
    23761 accttatgtt ttgacaattc ttgtcttagc agccttcttt ggaaaagcag tcgcaccaaa
    23821 agcagatggt atcaactaca tcaaatcaaa ataagcatac aaaaaaacgt cagttcaatg
    23881 actgaactgc cccccaaaag ttagacagaa aaaatctaac ttttggggtg tttttattat
    23941 gaaactaact tatgatgata aagttcagat ctatgaactt agaaaacaag gatatagctt
    24001 agagaagctt tcaaataaat ttgggataaa caattctaat cttaggtaca tgattaaatt
    24061 gattgatcgt tacggaatag agttcgtcaa aaaagggaaa aatcgttact attctcctga
    24121 tttaaaacaa gaaatgattc ataaagtctg acatgaaggc tagactaaag atagagtttc
    24181 tcttgaatac ggtctcccaa gtcgtacgat acttcttaac tggctagcac aataca
//
LOCUS       DBEJHE010000028        23980 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC4 isolate 671759
            SAMN38261586-rid24793303.denovo.28, whole genome shotgun sequence.
ACCESSION   DBEJHE010000028 DBEJHE010000000
VERSION     DBEJHE010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261586
            Sequence Read Archive: SRR26833752
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 23980)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23980)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576136.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576136.1
            Genome Coverage       :: 109x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 19:48:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,067
            CDSs (total)                      :: 2,029
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 131
            CDSs (without protein)            :: 131
            Pseudo Genes (ambiguous residues) :: 0 of 131
            Pseudo Genes (frameshifted)       :: 64 of 131
            Pseudo Genes (incomplete)         :: 59 of 131
            Pseudo Genes (internal stop)      :: 46 of 131
            Pseudo Genes (multiple problems)  :: 32 of 131
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23980
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261586-rid24793303.denovo.28"
                     /strain="GPSC4"
                     /isolate="671759"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            <1..661
                     /locus_tag="ACL3EZ_001558"
     CDS             <1..661
                     /locus_tag="ACL3EZ_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0393101.1"
                     /translation="FYLNKGKVYGFVGPNGAGKTTIIKMILGILKPDSGKITIFNQTV
                     EQNSENILSRIGLVLGPSFYGHLDAYKNLKLIANMKGLSLDTERLNEYLSMVGLKDVK
                     KKKVKNFSMGMKQRLSIAASLLGSPEILIWDEPINGLDPQGVIEIRSLIRFLQEKKGI
                     TFLISSHILSELDKVISDIIIINYGKVEFFGSCHYLLQKYNCRNLEEAYLACLAGGEY
                     D"
     gene            654..1391
                     /locus_tag="ACL3EZ_001559"
     CDS             654..1391
                     /locus_tag="ACL3EZ_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0393102.1"
                     /translation="MIKLEFLKQKKSILWFVLIFPIILNVLLYIDLTFRYRGYLLVHQ
                     NELALSNWQLIFKEQTIFYFSELFYLVLSLIIYEVFAVEFKNDAWLTVISLPFRNKYT
                     INSKLLITVVYTFTFWLSDYISLYVIGKAIDNSLEIGLIFFLKTFTIQLISSLMIMLL
                     YFLTLVLIRKISGIIPIGIIMMILTISIYYNDYNFKIYLPFTYLSHAFRVTESQFYMI
                     LLSNIIIIVLFYILIRKLNERSFEMKL"
     gene            1404..2114
                     /locus_tag="ACL3EZ_001560"
     CDS             1404..2114
                     /locus_tag="ACL3EZ_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0393103.1"
                     /translation="MKLLKNELIKSKIFLFIIVDICIQILVILAIKTYILDISALYSE
                     LDYNKYWYILHTLIYMLMIFPIQILYQNLREALIEDNNNGWNIMVINTNNLVKIIYIK
                     VTINIVRCFICYFVYTIFSLIQLGGMGTDMLLTNIIFPNIMSFLLFLPIAIFMQICCI
                     RFDSILAKALPNILLILIVLITFQSDWNIFTPATYYYTEIQSTTNLGIKLLVCIWIMG
                     FEFFLLPKLIKLKEQNLV"
     gene            2656..2877
                     /locus_tag="ACL3EZ_001561"
     CDS             2656..2877
                     /locus_tag="ACL3EZ_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGR0393104.1"
                     /translation="MYRRLRDLREDHDLTQKQIAKILSFTNSAYAKIERGEHTLTADV
                     LVTLSNFYDVSTDYLLELTDFPDKIRFRK"
     gene            3323..3647
                     /locus_tag="ACL3EZ_001562"
                     /pseudo
     CDS             3323..3647
                     /locus_tag="ACL3EZ_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0032196 - transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            3775..5004
                     /locus_tag="ACL3EZ_001563"
     CDS             3775..5004
                     /locus_tag="ACL3EZ_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HGR0393105.1"
                     /translation="MKISKRHLLNYSILIPYLLLSILGLIVVYSTTSAILIEEGKSAL
                     QLVRNQGIFWIVSLILIALIYKLRLDFLRNERLIILVILIEMLLLFLARFIGISVNGA
                     YGWISVAGVTIQPAEYLKIIIIWYLAHRFSKQQEEIATYDFQVLTQNQWLPRAFNDWR
                     FVLLVLIGSLGIFPDLGNATILVLVSLIMYTVSGIAYRWFSTILALVSAASVFVLTTI
                     SLIGVETFSKIPVFGYVAKRFSAFFNPFADRADAGHQLANSYFAMVNGGWFGLGLGNS
                     IEKRGYLPEAHTDFVFSIVIEEFGFAGASLILALLFFMILRIILVGIRAENPFNAMVA
                     LGVGGMMLVQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVAVAFVLNIDASEKR
                     AKLYRELENQPMNLLLK"
     gene            5024..7720
                     /gene="ppc"
                     /locus_tag="ACL3EZ_001564"
     CDS             5024..7720
                     /gene="ppc"
                     /locus_tag="ACL3EZ_001564"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008964 - phosphoenolpyruvate carboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA];
                     GO_process: GO:0015977 - carbon fixation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HGR0393106.1"
                     /translation="MSLQKLENYSNKSVVQEEVLILTELLEDITKNMLAPETFEKIIQ
                     LKELSTQEDYQGLNRLVTSLSNDEMVYISRYFSILPLLINISEDVDLAYEINHQNNID
                     QDYLGKLSTTIKLVAEKENAVEILEHLNVVPVLTAHPTQVQRKSMLDLTNHIHSLLRK
                     YRDVKLGLINKDKWYNDLRRYIEIIMQTDMIREKKLKVTNEITNAMEYYNSSFLKAVP
                     HLTTEYKRLAQAHGLNLKQAKPITMGMWIGGDRDGNPFVTAETLKQSALTQCEVIMNY
                     YDKKIYQLYREFSLSTSIVNVSKQVREMARQSKDNSIYREKELYRRALFDIQSKIQAT
                     KTYLIEDEEVGTRYETANDFYKDLIAIRDSLLENKGESLISGDFVELLQAVEIFGFYL
                     ASIDMRQDSSVYEACVAELLKSAGIHSRYSELSEEEKCDLLLKELEEDPRILSATHAE
                     KSELLAKELAIFKTARVLKDKLGDDVIRQTIISHATSLSDMLELAILLKEVGLVDTER
                     ARVQIVPLFETIEDLDHSEETMRKYLSLSLAKKWIDSRNNYQEIMLGYSDSNKDGGYL
                     SSCWTLYKAQQQLTAIGDEFGVKVTFFHGRGGTVGRGGGPTYEAITSQPLKSIKDRIR
                     LTEQGEVIGNKYGNKDAAYYNLEMLVSAAINRMITQKKSDTNTPNRYEAIMDQVVDRS
                     YDIYRDLVFGNEHFYDYFFESSPIKAISSFNIGSRPAARKTITEIGGLRAIPWVFSWS
                     QSRVMFPGWYGVGSSFKEFINKNPENIAILRDMYQNWPFFQSLLSNVDMVLSKSNMNI
                     AFEYAKLCEDEQVKAIYETILNEWQVTKNVILAIEGHDELLADNPYLKASLDYRMPYF
                     NILNYIQLELIKRQRRGELSSDQERLIHITINGIATGLRNSG"
     misc_binding    7803..8020
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            8133..9137
                     /gene="trpX"
                     /locus_tag="ACL3EZ_001565"
     CDS             8133..9137
                     /gene="trpX"
                     /locus_tag="ACL3EZ_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan ABC transporter substrate-binding
                     protein"
                     /protein_id="HGR0393107.1"
                     /translation="MKNKRLIGIIAALAVLVAGSLIYSSMNKSEAQNNKDEKKITKIG
                     VLQFVSHPSLDLIYKGIQDGLAEEGYKDDQVKIDFMNSEGDQSKVATMSKQLVANGND
                     LVVGIATPAAQGLASATKDLPVIMAAITDPIGANLVKDLKKPGGNITGVSDHNPAQQQ
                     VELIKALTPNVKTIGALYSSSEDNSKTQVEEFKAYAEKAGLTVETFAVPSTNEIASTV
                     TVMTSKVDAIWVPIDNTIASGFPTVVSSNQSSKKPIYPSATAMVEVGGLASVVIDQHD
                     LGVATGKMIVQVLKGAKPADTPVNVFSTGKSVINKKIAQELGITIPESVLKEAGQVIE
                     "
     gene            9206..10072
                     /locus_tag="ACL3EZ_001566"
     CDS             9206..10072
                     /locus_tag="ACL3EZ_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0393108.1"
                     /translation="MIVSIISQGFVWAILGLGIFMTFRILNFPDMTTEGSFPLGGAVA
                     VTLITKGVNPFLATLVAVGAGCLAGMAAGLLYTKGKIPTLLSGILVMTSCHSIMLLIM
                     GRANLGLLGTKQIQDVLPFDSDLNQLLTGLIFVSIVIALMLFFLDTKLGQAYIATGDN
                     PDMARSFGIHTGRMELMGLVLSNGVIALAGALIAQQEGYADVSRGIGVIVVGLASLII
                     GEVIFKSLSLAERLVTIVVGSIAYQFLVWAVIALGFNTSYLRLYSALILAVCLMIPTF
                     KQTILKGAKLSK"
     gene            10069..10827
                     /locus_tag="ACL3EZ_001567"
     CDS             10069..10827
                     /locus_tag="ACL3EZ_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0393109.1"
                     /translation="MTAIVELKNATKIVKNGFDEEKIILNDVSLEIFERDFITILGGN
                     GAGKSTLFNTIAGTLSLTSGTIRILGEELTKFSPEKRAKYLSRVFQDPKMGTAPRMTV
                     AENLLIAKFRGEKRGLLPRRLTSYKDEFQATIEKVGNGLEKHLNTPIEFLSGGQRQAL
                     SLLMATLKRPELLLLDEHTAALDPKTSVALMELTDEFVKKDQLTALMITHHMEDALKY
                     GNRLIVMKEGRIIQDLNQEEKAKMKISDYYQLFE"
     gene            10917..12677
                     /gene="dnaG"
                     /locus_tag="ACL3EZ_001568"
     CDS             10917..12677
                     /gene="dnaG"
                     /locus_tag="ACL3EZ_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000227865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003896 - DNA primase activity [Evidence
                     IEA];
                     GO_process: GO:0006269 - DNA replication, synthesis of
                     primer [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HGR0393110.1"
                     /translation="MVDKQVIEEIKNNANIVEVIGDVISLQKAGRNYLGLCPFHGEKT
                     PSFNVVEDKQFYHCFGCGRSGDVFKFIEEYQGVPFIEAVQILGQRVGIEVEKPLYSEQ
                     KPASPHQALYDMHEDAAKFYHAILMTTTMGEEARNYLYQRGLTDEVLKHFWIGLAPPE
                     RNYLYQRLSDQYREEDLLDSGLFYLSDANQFVDTFHNRIMFPLTNDQGKVIAFSGRIW
                     QKTDSQTSKYKNSRSTAIFNKSYELYHMDRAKKSSGKASEIYLMEGFMDVIAAYRAGI
                     ESAVASMGTALSREHVEHLKRLTKKLVLVYDGDKAGQAATLKALDEIGDMPVQIVSMP
                     DNLDPDEYLQKNGPEDLAYLLTKTRISPIEFYIHQYKPENSENLQAQIEFLEKIAPLI
                     VQEKSIAAQNSYIHILADSLASFDYTQIEQIVNESRQVQRQNRMEGISRPTPITMPIT
                     KQLSAIMRAEAHLLYRMMESPLVLNDYRLREDFAFATPEFQVLYDLLGQYGNLPPEVL
                     AEQTEEVERAWYQVLAQDLPAEISPQELSEVEMTRNKALLNQDNMRIKKKVQEASHVG
                     DTDTALEELERLISQKRRME"
     gene            12680..13789
                     /gene="rpoD"
                     /locus_tag="ACL3EZ_001569"
     CDS             12680..13789
                     /gene="rpoD"
                     /locus_tag="ACL3EZ_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HGR0393111.1"
                     /translation="MATKQKEVTTFDVQVAEFIRNHKQKGTATDDEINASLVIPFTLD
                     ADGIEDLLQRIQDAGISITDNEGNPSARVLSNEEEPELSDEDLIGSTSAKVNDPVRMY
                     LKEIGVVPLLTNEEEKELALAVEAGDIEAKQRLAEANLRLVVSIAKRYVGRGMQFLDL
                     IQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LVREQRNLLQELGQDPTPEQIAERMDMTPDKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDEVIENPVDYTTRIVLREQLDEILDTLTDREENVLRLRFGLDDGKMRTLEDVGK
                     VFNVTRERIRQIEAKALRKLRQPSRSKPLRDFIED"
     gene            13803..14132
                     /locus_tag="ACL3EZ_001570"
     CDS             13803..14132
                     /locus_tag="ACL3EZ_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HGR0393112.1"
                     /translation="MAYTEEQIENIKTRILTALEEVIDPELGIDIVNLGLIYEIRFDG
                     DTGQTEIDMTLTTMGCPLADLLTDQIYDAMIEVPEVTDTEVKLVWYPAWTVEKMSRYA
                     RIALGIK"
     gene            14166..15290
                     /gene="cpoA"
                     /locus_tag="ACL3EZ_001571"
     CDS             14166..15290
                     /gene="cpoA"
                     /locus_tag="ACL3EZ_001571"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosylglucosyldiacylglycerol synthase"
                     /protein_id="HGR0393113.1"
                     /translation="MRKFPLFSSSLSFLLLILFKENDIIVVMEKKKLRINMLSSSEKV
                     AGQGVSGAYRELVRLLHRAAKDQLIVTENLPIEADVTHFHTIDFPYYLSTFQKKRSGR
                     KIGYVHFLPATLEGSLKIPFFLKGIVKRYVFSFYNRMEHLVVVNPMFIEDLVAAGIPR
                     EKVTYIPNFVNKEKWHPLPQEEVVRLRTDLGLSDNQFIVVGAGQVQKRKGIDDFIRLA
                     EELPQITFIWAGGFSFGGMTDGYEHYKKIMENPPKNLIFPGIVSPERMRELYALADLF
                     LLPSYNELFPMTILEAASCEAPIMLRDLDLYKVILEGNYRATAGREEMKEAILEYQAN
                     PAVLKDLKEKAKNISREYSEEHLLQIWLDFYEKQAALGRK"
     gene            15306..16631
                     /locus_tag="ACL3EZ_001572"
     CDS             15306..16631
                     /locus_tag="ACL3EZ_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HGR0393114.1"
                     /translation="MRIGLFTDTYFPQVSGVATSIRTLKTELEKQGHAVFIFTTTDKD
                     VNRYEDWQIIRIPSVPFFAFKDRRFAYRGFSKALEIAKQYQLDIIHTQTEFSLGLLGI
                     WIARELKIPVIHTYHTQYEDYVHYIAKGMLIRPSMVKYLVRGFLHDVDGVICPSEIVR
                     DLLSDYKVKVEKRVIPTGIELAKFERPEIKQENLKELRSKLGIQDGEKTLLSLSRISY
                     EKNIQAVLAAFADVLKEEDKVKLVVAGDGPYLNDLKEQAQNLEIQDSVIFTGMIAPSE
                     TALYYKAADFFISASTSETQGLTYLESLASGTPVIAHGNPYLNNLISDKMFGTLYYGE
                     HDLAGAILEALIATPDMNEHTLSEKLYEISAENFGKRVHEFYLDAIISNNFQKDLAKD
                     DTVSQRIFKTVLYLQQQVVAVPVKGSRRMLKASKTQLISMRDYWKDHEE"
     gene            16662..16838
                     /locus_tag="ACL3EZ_001573"
     CDS             16662..16838
                     /locus_tag="ACL3EZ_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HGR0393115.1"
                     /translation="MRSGRDKKIAGVCAGVAHYLDMDPTIVQVIWGVLTCCYGAGIVA
                     YIILWIIAPVATDY"
     gene            16897..17031
                     /locus_tag="ACL3EZ_001574"
     CDS             16897..17031
                     /locus_tag="ACL3EZ_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HGR0393116.1"
                     /translation="MAFGDNGNRKKTMFEKITLFIVIIMLVASLLGIFATAIGALSNL
                     "
     gene            17095..18405
                     /gene="obgE"
                     /locus_tag="ACL3EZ_001575"
     CDS             17095..18405
                     /gene="obgE"
                     /locus_tag="ACL3EZ_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HGR0393117.1"
                     /translation="MSMFLDTAKIKVKAGNGGDGMVAFRREKYVPNGGPWGGDGGRGG
                     NVVFVVDEGLRTLMDFRYNRHFKADSGEKGMTKGMHGRGAEDLRVRVPQGTTVRDAET
                     GKVLTDLIEHGQEFIVAHGGRGGRGNIRFATPKNPAPEISENGEPGQERELQLELKIL
                     ADVGLVGFPSVGKSTLLSVITSAKPKIGAYHFTTIVPNLGMVRTQSGESFAVADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHIIDMSASEGRDPYEDYLAINKELESYNLRLME
                     RPQIIVANKMDMPESQENLEEFKKKLSENYDEFEELPAIFPISGLTKQGLATLLDATA
                     ELLDKTPEFLLYDESDMEEEAYYGFDEEEKAFEISRDDDATWVLSGEKLMKLFNMTNF
                     DRDESVMKFARQLRGMGGDEALRARGAKDGDLVRIGKFEFEFVD"
     gene            18415..18573
                     /locus_tag="ACL3EZ_001576"
     CDS             18415..18573
                     /locus_tag="ACL3EZ_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0393118.1"
                     /translation="MGDKPISFRDADGNFVSAADVWNEKKLEELFNRLNPNRALRLAR
                     TKKENPSQ"
     gene            19660..20919
                     /locus_tag="ACL3EZ_001577"
     CDS             19660..20919
                     /locus_tag="ACL3EZ_001577"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008760 - UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0019277 - UDP-N-acetylgalactosamine
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HGR0393119.1"
                     /translation="MRKIVINGGLPLQGEITISGAKNSVVALIPAIILADDVVTLDCV
                     PDISDVASLVEIMELMGATVKRYDDVLEIDPRGVQNIPMPYGKINSLRASYYFYGSLL
                     GRFGEATVGLPGGCDLGPRPIDLHLKAFEAMGATASYEGDNMKLSAKDTGLHGASIYM
                     DTVSVGATINTMIAAVKANGRTIIENAAREPEIIDVATLLNNMGAHIRGAGTNIIIID
                     GVERLHGTRHQVIPDRIEAGTYISLAAAVGKGIRINNVLYEHLEGFIAKLEEMGVRMT
                     VSEDSIFVEEQSNLKAINIKTAPYPGFATDLQQPLTSLLLRANGRGTIVDTIYEKRVN
                     HVFELAKMDADISTTNGHILYTGGRDLRGASVKATDLRAGAALVIAGLMAEGKTEITN
                     IEFILRGYSDIIEKLRNLGADIRLVED"
     gene            20935..21486
                     /locus_tag="ACL3EZ_001578"
     CDS             20935..21486
                     /locus_tag="ACL3EZ_001578"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR0393120.1"
                     /translation="MNIWTKLAMFSFFETDRLYLRPFFFSDSQDFREIASNPENLQFI
                     FPTQASLEESQYALANYFMKSPLGVWAICDQKNQQMIGSIKFEKLDEIKKEAELGYFL
                     RKDAWSQGFMTEVVRKICQLSFEEFGLKQLFIITHLENEASQRVALKSGFSLFRQFKG
                     SDRYTRKMRDYLEFRYVKGEFNE"
     gene            21479..22756
                     /gene="spxR"
                     /locus_tag="ACL3EZ_001579"
     CDS             21479..22756
                     /gene="spxR"
                     /locus_tag="ACL3EZ_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS-HotDog domain-containing transcription
                     factor SpxR"
                     /protein_id="HGR0393121.1"
                     /translation="MSKHQEILSYLEELPVGKRVSVRSISNHLGVSDGTAYRAIKEAE
                     NRGIVETRPRSGTIRVKSQKVAIERLTFAEIAEVTSSEVLAGQEGLEREFSKFSIGAM
                     TEQNILSYLHDGGLLIVGDRTRIQLLALENENAVLVTGGFQVHDDVLKLANQKGIPVL
                     RSKHDTFTVATMINKALSNVQIKTDILTVEKLYRPSHEYGFLRETDTVKDYLDLVRKN
                     RSSRFPVINQHQVVVGVVTMRDAGDKSPSTTIDKVMSRSLFLVGLSTNIANVSQRMIA
                     EDFEMVPVVRSNQTLLGVVTRRDVMEKMSRSQVSALPTFSEQIGQKLSYHHDEVVITV
                     EPFMLEKNGVLANGVLAEILTHMTQDLVVNSGRNLIIEQMLIYFLQAVQIDDILRIQA
                     RIIHHTRRSAIIDYDIYHGHQIVSKANVTVKIN"
     gene            22772..23632
                     /locus_tag="ACL3EZ_001580"
     CDS             22772..23632
                     /locus_tag="ACL3EZ_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HGR0393122.1"
                     /translation="MITLKSAREIEAMDKAGDFLASIHIGLRDLIKPGVDMWEVEEYV
                     RRRCKEENFLPLQIGVDGAMMDYPYATCCSLNDEVAHAFPRHYILKDGDLLKVDMVLG
                     GPIAKSDLNVSKLNFNNVEQMKKYTQSYSGGLADSCWAYAVGTPSEEVKNLMDVTKEA
                     MYKGIEQAVVGNRIGDIGAAIQEYAESRGYGVVRDLVGHGVGPTMHEEPMVPNYGIAG
                     RGLRLREGMVLTIEPMINTGDWEIDTDMKTGWAHKSIDGGLSCQYEHQFVITKDGPVI
                     LTSQGEEGTY"
     gene            23857..>23980
                     /locus_tag="ACL3EZ_001581"
     CDS             23857..>23980
                     /locus_tag="ACL3EZ_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001136123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase"
                     /protein_id="HGR0393123.1"
                     /translation="MSQSIVPVEIPQYCRFDSKKRNGILFNVRIANLKFTFFRLD"
BASE COUNT         7437 a         3980 c         5192 g         7371 t
ORIGIN      
        1 attttattta aataagggaa aagtatatgg ttttgttgga ccaaatgggg ctggaaaaac
       61 tacaattatc aaaatgattc tagggatttt aaaaccagat tctgggaaaa taactatttt
      121 taatcaaacc gtagaacaga attccgaaaa tatattatct aggataggat tagttttggg
      181 accttcattt tatggtcatc ttgatgctta taaaaatttg aagttaatag caaatatgaa
      241 agggcttagt ttagatactg aaagacttaa tgaatatcta tcaatggtag gattaaaaga
      301 tgttaaaaag aaaaaagtga aaaatttttc aatgggcatg aaacaacgtc taagtatagc
      361 tgcatcattg ttaggtagtc cagaaatatt aatttgggat gaaccaatca atggacttga
      421 tccacagggt gtaattgaaa ttagaagttt aatccgtttt ctacaggaga aaaaaggtat
      481 tacattttta atatcaagtc atattcttag tgaactggat aaagtgatat ctgatattat
      541 aattataaat tatgggaaag ttgaattttt tggttcttgc cactaccttt tacaaaagta
      601 taattgtcga aatctggaag aagcctactt agcttgttta gctggaggtg aatatgatta
      661 aattagagtt tctaaagcag aaaaaaagca tcttatggtt tgttcttatt tttccaataa
      721 ttctgaatgt tttgttatat atagacttaa cttttaggta tcgaggttat ttattggtgc
      781 atcaaaatga acttgcttta tctaattggc agttaatttt taaagaacaa acaatatttt
      841 atttttctga actattttat ttagttctat ctttaataat ttacgaagtg tttgcagtag
      901 aatttaaaaa tgatgcatgg ttaaccgtaa tttcattgcc atttagaaac aagtacacaa
      961 taaattctaa attactcatt acagtggttt acacatttac tttttggttg tctgattata
     1021 ttagcttata cgttattggg aaggctattg ataacagttt agagattggt ttgattttct
     1081 ttttaaaaac atttaccatt caattaattt cctcgttgat gataatgtta ttatattttc
     1141 taactttagt acttataagg aaaatttctg gaataatacc aattggtatt ataatgatga
     1201 ttttaacaat tagcatatac tacaacgatt ataattttaa gatttactta ccatttactt
     1261 atctttctca tgcttttaga gtgactgaaa gtcaatttta tatgatttta ctatctaata
     1321 taataatcat cgtacttttt tatatattaa ttcgtaaatt gaacgaaaga agttttgaga
     1381 tgaaacttta ataggtaata aaaatgaagt tacttaaaaa tgaattgatt aagagtaaaa
     1441 tatttttatt tattattgtt gacatctgta ttcagattct agtcattcta gctataaaaa
     1501 catatatttt agatatttcg gcactatact cagagcttga ttataataag tattggtata
     1561 ttttacacac tttaatatat atgctaatga tttttcctat acaaattttg tatcaaaatc
     1621 taagagaggc attgattgaa gataataata atggttggaa tatcatggtg attaacacta
     1681 ataatctcgt gaaaatcatc tatataaaag taacgataaa tatcgtgaga tgttttattt
     1741 gttattttgt ttatacaatt ttttctttaa ttcaattagg tggtatggga actgatatgt
     1801 tattaaccaa tataatattt cccaatataa tgtcatttct tttattttta cctatagcta
     1861 tctttatgca aatttgctgt ataagatttg attccatttt agcaaaggcc ttacctaata
     1921 ttttgctgat acttattgtt ttaatcacgt ttcagagtga ttggaatata tttacacctg
     1981 caacttatta ttatacagaa attcagtcaa ctacaaactt aggtattaaa ttattagttt
     2041 gtatctggat tatgggattt gaatttttcc ttcttccaaa actaataaaa ttgaaagaac
     2101 aaaatctagt ttaaatgttg ctcgaaaatt aaataattga atacgattaa caatgaaaca
     2161 atacaacgtg agtcatgact tcaaagtaat tgattttatg attctggttt cttacgctta
     2221 attaagcaag ttgtattcac tttatcaaat tgttattact ctaaaaagcg tctaacagct
     2281 atagagtgtc tgtttgcttc tctttacttt tattttaaat aattcattaa ccttccgtaa
     2341 gtgcccaata ataaggtgtg ttgaagaagt ctgagataaa atagttctca gtcacaaaaa
     2401 agctatagat tcccattggt gaacagctcc ctgtcaagta gacagtaaaa taatataaaa
     2461 tcttaagcga cctgattcct gaattccagt ggagtcaggt tgttttttaa ccgtctttct
     2521 taatattgtc ttacctataa tagatatgct tatgagatat gtttaataaa ttaattttag
     2581 ttcaaaatgt ccagttagga cactttgaat gatttcttag ttttatatat tatacttttc
     2641 tcaggagaaa gctagatgta cagacgtttg agagatttga gggaagatca cgatttgacc
     2701 caaaaacaaa tagctaaaat actttcgttt acaaactcag cttatgctaa aattgaacgg
     2761 ggtgagcata cgttaacagc agatgtattg gtaactctct caaactttta cgatgtcagt
     2821 acagactacc tattggaatt gacagatttt cctgataaaa ttcgctttag aaaataatct
     2881 cctcaatttc atagagtgtg aaaatgagga gattttttat ttgttctttg aaaattaaat
     2941 agtccaaaat ggtactttcc tcatttgtgg agcaaatttg aatggctcgc catgataaga
     3001 gcgattttaa aaccatcaat aaaatagagc gatactttat atgccatgat acaaatgata
     3061 tacaatgata cttctgaccg ttcaggctgc catcgtaaaa gagcagcaag tgaaattctt
     3121 atgatgactt catcagtcat gccacgttaa atgtgtgagt ttgttagaga aacgcaatta
     3181 atcctcaaaa ggttccccga accttttgag ttccacagac gcatcacgtg gagtgtgtaa
     3241 gcttgttgct aaaagcgtaa aaaccttgga acgaaaggaa taatagactt cctgcgaaac
     3301 aaaaatacaa tacaataaaa ctatggatga tgaagcaagt aaacaattaa gcgatagccg
     3361 tttcaagagc cttgtaggtg ttcagcgcac gagatgttag ctgtgttaaa aacagcttat
     3421 caacgcaacg taaacgcgca aaaggtggac gaaaaaccaa attaagccta gacgatctcc
     3481 tcatggtaac tattcaatac atgcgagaat agcgcactta tgaacaaatt gcggctgatt
     3541 ttggcattca cgaaagcaac ttaatccgtc ggagccaatg ggttgaagta actcttgttc
     3601 aaaatggttt tacgatttca aattctgccc taattatgaa aaacagtaaa attcgaagga
     3661 ttgtaaggta agagtttttt tctttctgaa aaaatggtat aatagcaatc aaaactagaa
     3721 aataaaacgg aatttggaac agatttgtct gtatcctagt agagtggtga tgctatgaag
     3781 attagtaaga ggcacttatt aaattattcc atcttgattc cctacttgct tttatctatt
     3841 ttgggcttga ttgtggtcta ttcgaccacc agtgctattt taattgaaga aggcaagagc
     3901 gccttgcagt tggttcgaaa ccaaggaatc ttttggattg ttagtttgat actgattgcc
     3961 ttaatttata aattgagact agattttttg agaaatgagc gactaatcat tttagttata
     4021 ttaatagaaa tgcttttatt gttcttggct cgttttattg gtatttccgt aaacggggca
     4081 tacggttgga tttcggttgc aggagtaact attcagccag ctgagtactt aaaaatcatt
     4141 attatttggt atttagctca ccgattctcc aaacagcaag aagaaatagc tacttatgat
     4201 tttcaagttt tgactcaaaa tcaatggctt ccccgtgctt ttaatgattg gcgattcgtt
     4261 ctcctagttc tgattggaag tttgggaatt ttccctgatt taggaaatgc gactatttta
     4321 gtcttggttt ccttgattat gtatacagtt agtggaatcg cttatcgctg gttttcaacc
     4381 attctggcgc tcgtatctgc cgcttctgtc tttgtcttga ccactatcag cctaatcggt
     4441 gttgagacct tttcaaaaat tccagtattt ggctatgtag ccaagcgctt tagtgccttt
     4501 tttaatcctt ttgccgatcg tgctgatgca ggtcaccagt tagctaattc ttattttgcc
     4561 atggtcaatg gtggttggtt tggtctaggt cttggaaact cgattgaaaa acgaggttat
     4621 ttgccagaag ctcatacaga ctttgtcttt tctatcgtga ttgaagaatt tggctttgct
     4681 ggtgccagtc ttattttagc tctcttgttt ttcatgattt tgcggattat cttggtcggt
     4741 attcgagcgg agaatccttt caatgccatg gttgcactcg gtgtcggagg gatgatgttg
     4801 gttcaggtat ttgtcaatat cggagggatt tcgggcttga ttccatctac aggagtaacc
     4861 ttccccttct tatcccaggg tggaaatagt cttctagtct tatcagtggc agtagccttt
     4921 gtcttaaata ttgatgccag tgaaaaacgc gctaagttgt accgagaatt ggaaaatcaa
     4981 ccaatgaacc ttctgttgaa gtaggataaa gaaaggatag tttatgtctc ttcaaaaatt
     5041 agaaaattat agtaataaaa gtgttgtgca agaagaagtc ttgattctaa cagaattact
     5101 ggaagatatt actaaaaata tgcttgcccc agagaccttt gaaaaaataa tacagttgaa
     5161 agaattatca acgcaggaag attatcaagg tctaaaccgt ctagtgacta gcttatcaaa
     5221 tgatgaaatg gtctatattt cacgctattt ctctatctta cctcttttga tcaatatttc
     5281 agaggatgtg gatttagctt atgaaatcaa tcatcaaaat aatattgatc aggactattt
     5341 aggtaaatta tctacaacga ttaaattggt agcagaaaag gaaaatgccg ttgagatcct
     5401 agaacacttg aatgttgtcc ctgttttgac agcccatcca acacaagtgc aacgcaaaag
     5461 tatgttggat ttaacaaatc atattcatag tcttttgcgt aaataccgtg atgttaagtt
     5521 ggggttgatc aataaagata aatggtacaa tgatttgcgt cgttacatcg aaattatcat
     5581 gcagacagac atgattcgtg agaaaaaatt aaaagtgact aacgaaatca cgaatgctat
     5641 ggaatattat aacagctcct ttttgaaagc tgtacctcat ttgacgacgg agtataagcg
     5701 cttagcgcaa gcgcatggtc tgaatttaaa acaggctaaa ccaatcacca tgggtatgtg
     5761 gataggtggt gaccgtgatg gaaatccatt tgttacagca gagaccttga agcagtctgc
     5821 actcactcaa tgtgaagtca tcatgaacta ctatgataaa aagatttacc aactttatcg
     5881 tgaattttct ctttcaacta gcattgtcaa cgtcagcaag caagtcagag aaatggctcg
     5941 tcaatccaag gataactcga tttaccgcga aaaagagctt taccgtcgtg ccttgtttga
     6001 tattcaatca aaaattcagg caactaaaac ctatctgatt gaggatgaag aagttgggac
     6061 tcgttatgaa accgccaatg atttctacaa ggatttgatt gccattcgag attctctact
     6121 agaaaataag ggtgagtcct tgatttcagg tgattttgtg gaattattgc aggcagtaga
     6181 gatatttggt ttttacctag catcaattga tatgcgacaa gactctagcg tctatgaagc
     6241 ctgtgtggca gaactcttga aatcagcagg aattcattct cgttatagcg agttgagcga
     6301 agaagaaaag tgtgaccttc tcttgaaaga attagaagaa gatccccgaa ttctttctgc
     6361 gactcacgca gaaaaatcag aattattagc aaaagaatta gctattttta agacggctcg
     6421 tgttttgaaa gataagttgg gagatgatgt catccgtcag accatcattt cacatgcaac
     6481 cagcctttct gatatgctag aattagctat tctgttaaaa gaagtaggac tggtggatac
     6541 ggaaagggcg cgtgttcaga ttgttcccct ttttgaaaca attgaagact tggatcattc
     6601 agaagaaaca atgagaaaat atctttctct tagccttgcc aaaaaatgga ttgactcacg
     6661 aaataactac caagaaatca tgcttggcta ctctgacagt aataaagatg gcggttactt
     6721 gtcatcatgt tggaccctct acaaggctca acaacaattg actgctattg gagatgaatt
     6781 tggcgttaag gttaccttct tccatggtcg tggtggtact gtcggtcgtg gtggtgggcc
     6841 aacctatgaa gccattacat ctcaaccgct caagtctatc aaggatcgta tccgcttgac
     6901 ggagcagggt gaagtaattg ggaataaata cggtaacaaa gacgccgctt actataacct
     6961 tgaaatgcta gtatcggcag ctattaaccg tatgattact cagaagaaga gcgataccaa
     7021 taccccaaat cgttatgaag ccattatgga tcaagtagtg gaccgtagtt acgatatcta
     7081 ccgtgatttg gtctttggta atgagcattt ctatgattat ttcttcgagt caagtccaat
     7141 caaggctatt tcaagtttta atattggttc tcgtccagcc gctcgtaaga ctattactga
     7201 aatcggtggt ttgcgtgcca tcccttgggt attctcatgg tcacagagtc gtgttatgtt
     7261 ccctggatgg tacggggttg gttcaagctt caaggaattt atcaataaaa atccagagaa
     7321 tattgctatc ttacgagata tgtaccaaaa ttggcctttc ttccaatcgc ttctttcaaa
     7381 tgttgatatg gttttgtcaa aatcaaatat gaatattgct tttgaatatg ctaaactttg
     7441 tgaagacgag caagttaagg ccatctatga gactatttta aatgaatggc aagttactaa
     7501 gaacgttatc ttggctattg aaggacatga cgaactctta gctgacaatc catatctaaa
     7561 agctagtctg gattaccgta tgccttactt taatattctc aactatattc agttagagtt
     7621 gattaaacgc caacgtcgtg gagaattgtc cagtgatcaa gaacgattga ttcatatcac
     7681 catcaacgga attgcgacag gattgcgtaa ttcaggttga taattttcaa gagtgaatgc
     7741 taaaagtgaa tatcaaaaaa attctaatag actattgaca agtagtttaa aaatgatata
     7801 atttaaccat tcagaaaagt aatcatacaa actttttaga gagtctgtgg tagctgaaaa
     7861 cagataagtg gcgatgatga aaattgggct gaatgctatt tagaatttga aattataaaa
     7921 attcggtaag cacaccttac agtgcatctc gttattgcga gactgagcga tagggaaatt
     7981 ccctataatt gaggtggtac cgcgcatcga cgtcctcaca caagtttttt gtgtgaggat
     8041 ttttttgatg gaggttagta tggaaagaaa acgatggcgt cgcttgttta gataagtgaa
     8101 atatgttaaa ggaaataaaa aggagaaaca gaatgaaaaa taaacgttta attggaatta
     8161 ttgctgcatt agcagtctta gtagcaggaa gcttgattta ttcttcaatg aataaatcag
     8221 aagctcagaa taataaggat gagaagaaaa taactaagat tggtgtgctt caatttgtga
     8281 gccatccatc ccttgatttg atttataaag ggatccaaga tggacttgca gaagaaggat
     8341 ataaagatga tcaagttaaa attgatttta tgaactcaga aggtgaccaa agtaaggttg
     8401 cgacaatgag taaacaattg gttgcaaatg ggaatgacct tgtggttggt atcgcaacac
     8461 cagcagccca agggttggct agtgcaacaa aagacctacc ggttatcatg gccgctatta
     8521 cagacccaat tggtgctaac ttggttaaag atttgaaaaa accaggtggc aacattacag
     8581 gggtatctga ccacaatcca gctcaacaac aagttgaact catcaaggct ctgacaccga
     8641 atgtgaaaac aatcggagct ctttactcaa gtagcgaaga caattcaaaa acacaggtcg
     8701 aagaatttaa ggcttatgct gaaaaagcag gtctgacagt ggaaacattt gcagttcctt
     8761 caacaaatga aattgcctca actgtcactg ttatgactag caaggtagat gctatttggg
     8821 ttccaattga taacaccatt gcatcaggat ttccaacggt tgtctctagc aatcaaagtt
     8881 ctaagaaacc aatttatccc agtgcgacag ctatggtaga agtaggtggt ttggcatcag
     8941 ttgtaattga ccaacatgac cttggtgtgg caacaggtaa aatgattgtg caagtcttga
     9001 aaggtgcaaa accagccgat accccagtca atgtcttttc aactggtaag tcagtcatca
     9061 ataaaaaaat agcacaagaa ctaggtatta ctattcctga gtctgttctc aaagaagcag
     9121 gacaagtcat cgaataaata aggtagggag gaggagactc ttcccatttt ttaaaaagat
     9181 gaatatagaa aggattaaat aaaatatgat tgtttccatt atttctcaag gatttgtctg
     9241 ggctattcta ggtctgggaa tctttatgac atttaggatt ttaaactttc cagatatgac
     9301 gacagaaggt tccttccctc ttgggggagc tgttgctgtc actttgataa ccaaaggcgt
     9361 gaacccattt ttagcgacac ttgttgctgt aggagcaggt tgtttggctg gaatggcagc
     9421 aggccttctt tatacaaaag ggaagatccc aaccttgctc tcagggattt tggtgatgac
     9481 ttcttgtcac tcaatcatgc tcttgattat gggacgtgcg aatttaggcc tgcttggaac
     9541 caagcaaatt caggatgttt tgccttttga ttcggatttg aatcaactct tgacaggtct
     9601 catctttgtg agtattgtta ttgctctcat gctctttttc ttggacacta aactcggaca
     9661 agcctatatt gctacagggg ataatcctga tatggctaga agtttcggga ttcatactgg
     9721 acgcatggag ctcatgggct tggtcttatc aaatggtgtg attgcccttg caggtgccct
     9781 cattgctcag caagaaggtt atgccgatgt gtctcgaggg atcggggtta tcgttgtggg
     9841 gcttgcaagt ttgattattg gagaagttat tttcaagagt ttgagcttgg cagagcgttt
     9901 ggttactatc gttgtaggtt ctatcgctta tcaattttta gtgtgggcag ttatcgcact
     9961 tggctttaat acaagttacc ttcgtttata cagtgccttg attttagcag tctgcctcat
    10021 gattccaaca tttaagcaaa caatcttgaa aggagccaag ttaagcaaat gacagcaatt
    10081 gtagaattaa aaaatgcaac caaaatcgtt aaaaatggct ttgatgaaga aaagattatt
    10141 ttaaatgatg tttccttaga aatttttgaa cgggacttta tcacgatttt gggcggaaat
    10201 ggtgctggaa aatcaaccct ctttaacact atagcaggga ccttatcact aactagtgga
    10261 actatccgta ttttaggtga agaactcact aagttttcac ccgagaagcg tgccaagtac
    10321 ctgtctcgtg tcttccaaga tccaaagatg gggacagctc cccgtatgac ggtcgctgaa
    10381 aatcttttaa tcgccaagtt tcgtggtgaa aagcgtggat tgttaccacg acgcttgact
    10441 agctataagg atgaatttca ggcaaccatt gaaaaagtag gaaatggtct tgagaaacac
    10501 ttgaatacac cgattgagtt cttatcaggt ggacaaagac aggctttgag tctcttgatg
    10561 gcaaccttga agcgacctga attactcctg ttagatgagc atactgctgc cctggatcca
    10621 aagactagtg ttgctttgat ggaattgaca gatgaatttg ttaagaaaga tcagctaaca
    10681 gcccttatga ttactcatca tatggaagat gctctcaaat acggcaatcg cttgattgtc
    10741 atgaaagaag gacggattat ccaagattta aaccaagaag aaaaagcaaa aatgaaaatc
    10801 tctgattatt atcaactctt tgaataaagt agggaaaatg agtgaaatgg tttacttttt
    10861 ttctgaaata aagtatacta tataaagtaa actatgataa catggaggta ttgtgtatgg
    10921 ttgacaaaca agtcattgaa gaaatcaaaa acaatgccaa cattgtggaa gtcataggag
    10981 atgtgatttc tttacaaaag gcaggacgga actatctagg gctctgtcct tttcatggtg
    11041 aaaaaacacc ttctttcaac gttgtagagg ataagcagtt ttatcactgt ttcggttgtg
    11101 gtcgctcagg tgatgtcttt aagttcatcg aggagtacca aggggttccc tttatagagg
    11161 cagtccaaat cttaggtcag cgtgttggaa ttgaggttga aaaaccgctt tatagtgagc
    11221 agaagccagc ctcacctcac caagctcttt atgatatgca cgaagatgca gccaaatttt
    11281 accatgcgat tctcatgaca acgactatgg gcgaagaggc cagaaattac ctttatcagc
    11341 gggggttgac agatgaagtg cttaaacatt tttggattgg tttagcacct ccagaacgaa
    11401 actatctcta tcaacgtttg tctgatcagt atcgtgaaga ggatttactg gattcaggcc
    11461 tgttttatct ctcggatgcc aatcaatttg tagacacctt tcacaatcgc attatgtttc
    11521 ccctgacaaa tgaccaagga aaggtcattg ccttctcagg tcgtatctgg caaaaaacgg
    11581 attcacaaac ttctaagtat aaaaacagcc gatcgactgc aatttttaac aaaagttacg
    11641 aattatatca tatggatagg gcaaaaaaat cttctggaaa agctagtgag atttacttga
    11701 tggaaggatt catggatgtt attgcagcct atcgggctgg aatcgaaagt gctgtggcgt
    11761 cgatgggaac ggccttgagt cgagagcatg ttgagcatct gaaaaggtta accaagaaat
    11821 tggttcttgt ttacgatgga gataaggctg ggcaagccgc gacattgaaa gcattggatg
    11881 aaattggtga tatgcctgtg caaatcgtca gcatgcctga taacttggat cctgatgagt
    11941 atctacaaaa aaatggtcca gaagacttgg cctatctatt aacgaaaact cgtattagtc
    12001 cgattgagtt ctacattcat cagtacaaac ctgaaaacag tgaaaatctg caggctcaga
    12061 ttgagtttct tgaaaaaata gctcccttga ttgttcaaga aaagtccatc gctgctcaaa
    12121 acagctatat tcatatttta gctgacagtc tggcgtcctt tgattatacc cagattgagc
    12181 agattgttaa tgagagtcgt caggtgcaaa ggcagaatcg catggaagga atttccagac
    12241 cgacgccaat caccatgcca atcaccaagc agttatcggc tattatgagg gcagaagccc
    12301 atctactcta tcggatgatg gaatcccctc ttgttttgaa cgattaccgt ttgcgagaag
    12361 actttgcatt tgctacacct gaatttcagg tcttatatga cttgcttggc cagtatggaa
    12421 atcttcctcc agaagtttta gcagagcaga cagaggaagt tgaaagagct tggtaccaag
    12481 ttttagctca ggatttgcct gctgaaatat cgccgcagga acttagtgaa gtagagatga
    12541 ctcgaaacaa ggctctcttg aatcaggaca atatgagaat caaaaagaag gtgcaggaag
    12601 ctagccatgt aggagataca gatacagccc tagaagaatt ggaacgttta atttcccaaa
    12661 agagaagaat ggagtaataa tggcaacaaa acaaaaagaa gtaacaacat ttgacgtaca
    12721 ggtagcagaa tttatccgta atcataagca aaaagggaca gcaacagatg atgaaatcaa
    12781 tgcaagtctg gttattcctt ttaccttgga cgctgatggg attgaagatc tcttgcaacg
    12841 gattcaggat gcaggaattt ctatcacaga taacgaagga aatccaagtg cgcgtgttct
    12901 tagcaatgaa gaagaaccag aactcagcga tgaggacttg attgggtcaa cttctgctaa
    12961 ggtcaatgac cctgtccgta tgtacttgaa agaaataggg gtcgttcctc tcttgaccaa
    13021 tgaagaggag aaagagttgg cactggctgt tgaagctggt gatatcgaag ccaaacaacg
    13081 tcttgcggaa gccaatcttc gtttggttgt ttccattgcc aaacgctatg tcggtcgtgg
    13141 tatgcagttc cttgacttga ttcaagaagg aaatatgggc ttgatgaagg cggttgacaa
    13201 gtttgactat tctaaagggt tcaagttttc aacttatgca acttggtgga ttcgtcaggc
    13261 tatcactcgt gctattgcgg accaagctcg taccatccgt atcccagttc acatggttga
    13321 aactatcaat aaattggttc gtgaacagcg gaatctcctt caagaattgg ggcaagatcc
    13381 gacaccagaa cagattgctg aacgaatgga tatgacacct gataaggttc gtgaaatctt
    13441 gaagattgcc caagaaccag tatctcttga aactcctatc ggtgaagagg acgatagcca
    13501 ccttggagac tttatcgaag atgaagtgat tgaaaatcca gtggattata cgactcgtat
    13561 cgtcttgcgt gagcaattgg atgaaatctt agatactctt acagaccgtg aagaaaatgt
    13621 tctgcgtcta cgttttggac tagatgatgg aaaaatgcgc acacttgaag atgtggggaa
    13681 agtctttaac gtaactcgtg agcgtatccg tcagattgaa gcaaaggctt tgagaaaact
    13741 acgccaacca agtcgtagca aaccgcttcg tgattttatt gaagactaag agtgaggaaa
    13801 atatggctta tacagaagag caaattgaaa acatcaaaac acggatttta acagccttgg
    13861 aagaagtcat cgaccctgag ttgggaatcg atattgtcaa tcttggtttg atctatgaga
    13921 ttcgttttga cggtgacaca gggcaaacag agattgacat gactttgaca actatgggtt
    13981 gtcccttagc agaccttttg acagaccaga tttatgatgc tatgatagag gttccagaag
    14041 taacggatac tgaggttaaa ttagtctggt atccagcctg gacagttgaa aaaatgagtc
    14101 gctatgcccg cattgcccta ggcattaagt aaacatataa aagcatgtga gagactgttg
    14161 gaaaagtgag gaaatttccc ctcttttcct ctagtctctc ctttcttttg ctgattttat
    14221 tcaaagaaaa tgatataata gtagttatgg agaaaaagaa attacgcatc aatatgttga
    14281 gttcaagtga gaaagtagca ggacagggag tttcaggtgc ttaccgtgaa ttagttcgtc
    14341 ttcttcaccg tgctgccaag gaccaattga ttgttacaga aaatcttcca atcgaggcag
    14401 atgtgactca ctttcatacg attgattttc cctattattt atcaaccttc caaaagaaac
    14461 gctcagggag aaagattggc tatgtgcatt tcttgccagc tacacttgag ggaagtttga
    14521 aaattccatt tttcttaaag ggaattgtga aacgctatgt attttctttt tacaaccgga
    14581 tggagcactt ggttgtggtc aatcctatgt ttattgagga tttggtagca gctggtattc
    14641 cacgtgaaaa agtgacctat attcctaact ttgtcaacaa ggaaaaatgg catcctctac
    14701 cacaagaaga ggtagttaga ctgcgcacag atcttggtct tagtgacaat cagtttatcg
    14761 tagtaggtgc tgggcaagtt cagaaacgta aagggattga tgactttatc cgtctggctg
    14821 aggaattgcc tcagattacc tttatctggg ctggtggctt ctcttttggt ggtatgacag
    14881 atggttatga acactataag aaaattatgg aaaatccccc taaaaatttg atttttccag
    14941 gcattgtatc gccagagcgg atgcgcgaat tgtatgctct agcggatctt ttcttgttgc
    15001 ctagttacaa tgagctcttt cctatgacta ttttagaagc tgcgagttgt gaggctccta
    15061 ttatgttgcg tgatttagat ctctataagg tgattttgga gggaaattat cgggcgacag
    15121 cgggtagaga agagatgaaa gaggctattt tggaatatca agcaaatcct gctgtcttaa
    15181 aagatctcaa agaaaaggct aagaatattt ccagagagta ttctgaagag catctgttac
    15241 aaatctggtt ggacttttat gagaaacaag ccgctttagg gagaaagtaa aaagtgaggt
    15301 aatctatgcg aattggttta tttacagata cctattttcc tcaggtttct ggtgttgcga
    15361 ccagtattcg aaccttgaaa acagaacttg aaaagcaggg acatgctgtt tttatcttta
    15421 cgacgacaga taaggatgtc aatcgctacg aagattggca aattatccgc attccaagtg
    15481 ttcctttctt tgcttttaag gatcgtcgct ttgcctaccg aggttttagc aaggcacttg
    15541 aaattgctaa acagtatcag ctagatatta tccatactca gacagaattt tctcttggcc
    15601 tgttggggat ttggattgcg cgtgaattga aaattccagt catccatacc tatcacaccc
    15661 agtatgaaga ctatgtccat tatattgcta aggggatgtt gatccggccg agtatggtca
    15721 agtatctggt tagaggtttc ctgcatgatg tggatggggt tatttgccct agtgagattg
    15781 tccgtgactt gctatctgat tataaggtca aggttgaaaa acgggtcatt cctactggga
    15841 ttgaattagc caagtttgag cgtccggaaa tcaagcagga aaatttgaaa gaactgcgta
    15901 gtaaactagg gattcaagat ggtgaaaaga cgttgcttag tctttcgaga atctcctatg
    15961 aaaaaaatat tcaagcagtt ttagcagcct ttgctgatgt tctgaaagag gaagacaagg
    16021 ttaaactggt agtagctggg gatggccctt atctgaatga cctcaaagag caagctcaga
    16081 acctagagat tcaagactca gtcatcttta cagggatgat tgctcctagt gagacggctc
    16141 tttactataa agcggcggat ttcttcattt cggcatcgac aagcgaaacg caaggtttga
    16201 cctacttgga aagcttagcc agtggaacac ctgtcattgc tcacggaaat ccttatttga
    16261 acaacctcat cagtgataaa atgtttggaa ccttgtacta tggagaacat gatttggctg
    16321 gtgctatttt ggaagccctg attgcaacac cagacatgaa cgagcatacc ttatcagaga
    16381 aattgtatga gatttcagct gagaactttg ggaaacgagt gcatgagttt tatctggatg
    16441 ccattatttc aaataacttc cagaaagatt tggctaaaga tgatacggtc agtcagcgta
    16501 tctttaagac agttttgtat cttcagcaac aggtggttgc tgtacctgta aaaggatcta
    16561 gacgcatgtt gaaggcttca aaaacacagt tgatcagtat gagagactat tggaaagacc
    16621 atgaagaata gaaagaggaa cagctatgaa aaaaacaatt aatgagaagc ggtcgtgata
    16681 aaaagattgc gggtgtttgt gctggggtgg cccattatct ggatatggat ccgactatcg
    16741 ttcaagtcat ttggggtgtt cttacttgct gttacggagc tggaattgta gcttacatta
    16801 ttttatggat tatcgcacca gtagcaactg actattgaaa actagctcaa ttcatgctaa
    16861 gataatagaa aatagaatgt aacgaaggag agaaaaatgg catttggaga taatggaaat
    16921 cgtaaaaaaa ctatgtttga gaaaataacc ttgtttatcg tgattatcat gctagtagca
    16981 agtttattgg gaatttttgc aactgcaatt ggtgccctca gtaatctata aaatagattc
    17041 aagaaaattt agtgactggg atttcccagc ccttttttaa agtgagaaga aataatgagt
    17101 atgtttttag atacagctaa gattaaggtc aaggctggta atggtggcga tggtatggtt
    17161 gcctttcgtc gtgaaaaata tgtccctaat ggaggccctt ggggtggtga tggtggtcgt
    17221 ggaggcaatg tggtcttcgt tgtagacgaa ggactacgta ccttgatgga tttccgctac
    17281 aatcgtcatt tcaaggctga ttctggtgaa aaagggatga ccaaagggat gcatggtcgt
    17341 ggtgctgagg accttagagt tcgagtacca caaggtacga ctgttcgtga tgcggagact
    17401 ggcaaggttt taacagattt gattgaacat gggcaagaat ttatcgttgc ccacggtggt
    17461 cgtggtggac gtggaaatat tcgtttcgcg acaccaaaaa atcctgcacc ggaaatctct
    17521 gaaaatggag aaccaggtca ggaacgtgag ttacaattgg aactaaaaat cttggcagat
    17581 gtcggtttag taggattccc atctgtaggg aagtcaacac ttttaagtgt tattacctca
    17641 gctaagccta aaattggtgc ctaccacttt accactattg taccaaattt aggtatggtt
    17701 cgcacccaat caggtgaatc ctttgcagta gccgacttgc caggtttgat tgaaggggct
    17761 agtcaaggtg ttggtttggg aactcagttc ctccgtcaca tcgagcgtac acgtgttatc
    17821 cttcacatca ttgatatgtc agctagcgaa ggccgtgatc catatgagga ttacctagct
    17881 atcaataaag agctggagtc ttacaatctt cgcctcatgg agcgtccaca gattattgta
    17941 gctaataaga tggacatgcc tgagagtcag gaaaatcttg aagaatttaa gaaaaaattg
    18001 tctgaaaatt atgatgaatt tgaagagtta ccagctatct tcccaatttc tggattgacc
    18061 aagcaaggtc tggcaacact tttagatgct acagctgaat tgttagacaa gacaccagaa
    18121 tttttgctct acgacgagtc cgatatggaa gaagaagctt actatggatt tgacgaagaa
    18181 gaaaaagcct ttgaaattag tcgtgatgac gatgcgacat gggtactttc tggtgaaaaa
    18241 ctcatgaaac tctttaatat gaccaacttt gatcgtgatg aatctgtcat gaaatttgcc
    18301 cgtcagcttc gtggtatggg gggtgatgaa gcccttcgtg cgcgtggagc taaagatggg
    18361 gatttggtcc gcattggtaa atttgagttt gaatttgtag actaggagac tggtatggga
    18421 gataaaccga tatctttccg agatgcggat ggtaattttg tttccgccgc agacgtttgg
    18481 aatgaaaaga aattggaaga actatttaat cgtctcaatc caaatcgtgc cttgagattg
    18541 gcacgaacta aaaaggaaaa tccatctcag taaagaagct aaaaaatccc gtgcctcatc
    18601 agacacggga ttttgtggta cgacaggcat gtatagcaaa ctgaatctgg aatagcacag
    18661 catatcttct aaaatattgc tataaattga tttgaatttc aaaattaaat tgttttattc
    18721 ttatttcaat ttgttatagt atatctgatg tcaaagttct cggcgagtca aatagtgatt
    18781 cccaagcctg actatcgtga ggtagcggat taaaatggtc tggggataga ccgttttaag
    18841 tctgatgctg gaaataagaa ttgtcagaag aagggatagc gaaatcgtgg ctctacgaac
    18901 aggaacgtga taataaggcg tatatagcga ataagagggc ctcaaactct aaagtccaaa
    18961 aaggtagtcg taacctatat gcgtaaatca tgagagtaat tgaattcgta ctaagatttt
    19021 ctatttttac tgtaaccttt taacgtcctc atatcttgta tacacgagga aagatgtacg
    19081 acttatcccg tgaggtctat cactataaag agaaaacgac agatagaagt gatcctgagt
    19141 cacggttatc tttaaaatag attgtctgat aggatgctag cctgaaaacg tcttgttcat
    19201 gaaatatagg acggtatgta taaaacgctt ctgtgaactg agagaagggg gagaagttct
    19261 tgctaaaatt tagttgaaca gccgtattcc gatacttaga taagagatct agtcttagct
    19321 cctactcagt ttcaggggat aaaaaagggg caatagcgat tcgagaaaga ttatactctt
    19381 cgaaaatctc ttcaaatcac gtcaatatcg ccttgccgta tgtgtaggat actaactacg
    19441 tcagttccat ctacaatctc aaaacagtgt tttgagcaac ctgcggctag tttcctagtt
    19501 tgatctttga tttttattga gtattagtaa ttcagttact aactcgtcaa ctctgattta
    19561 tccaataaaa ttgaaaagga tggaaaaaag gataaattta tgatatactt tattttgaag
    19621 accttattag aaatcttgaa agagtattga aaacttagaa tgagaaaaat tgttatcaat
    19681 ggtggattac cactgcaagg tgaaattact attagtggtg ctaaaaatag tgttgtggcc
    19741 ttaattccag ctattatatt ggctgatgat gtggtgactt tggattgtgt tccagatatt
    19801 tcggatgtag ccagtcttgt cgaaatcatg gaattaatgg gagctactgt taagcgttat
    19861 gacgatgtct tggagattga tccaagaggt gttcaaaata ttccaatgcc ttatggtaaa
    19921 attaacagtc ttcgtgcatc ttactatttt tatgggagcc tcttaggccg ttttggtgaa
    19981 gcgacagttg gtctaccggg aggatgtgat cttggtcctc gtccgattga cttacacctt
    20041 aaggcgtttg aagctatggg tgccactgct agctacgagg gagataacat gaagttatct
    20101 gctaaagata caggacttca tggtgcaagt atttacatgg atacggttag tgtgggagca
    20161 acgattaata cgatgattgc tgcggttaaa gcaaatggtc gtactattat tgaaaatgca
    20221 gcccgtgaac ctgagattat tgatgtagct actctcttga ataatatggg tgcccatatc
    20281 cgtggggcag gaactaatat catcattatt gatggtgttg aaagattaca tgggacacgt
    20341 catcaggtga ttccagaccg cattgaagct ggaacatata tatctttagc tgctgcagtt
    20401 ggtaaaggaa ttcgtataaa taatgttctt tacgaacacc tggaagggtt tattgctaag
    20461 ttggaagaaa tgggagtgag aatgactgta tctgaagaca gcatttttgt cgaggaacag
    20521 tctaatttga aagcaatcaa tattaagaca gctccttacc caggctttgc aactgatttg
    20581 caacaaccgc ttacctctct tttactaaga gcgaatggtc gtggtacaat tgtcgatacg
    20641 atttacgaaa aacgtgtaaa tcatgttttt gaactagcaa agatggatgc ggatatttcg
    20701 acaacaaatg gtcatatttt gtacacgggt ggacgtgatt tacgtggggc cagtgttaaa
    20761 gcgaccgact taagagctgg ggctgcacta gtcattgctg ggcttatggc tgaaggtaaa
    20821 actgaaatta ccaatatcga gtttatctta cgtggttatt ctgatattat cgaaaaatta
    20881 cgtaatttag gagcggatat tagacttgtt gaggattaaa ccgtagaggt gtttatgaat
    20941 atttggacca aattagcaat gttttctttt tttgaaacgg atcgcttgta tttgcgtcct
    21001 ttctttttta gtgatagtca ggacttccgc gagatagctt caaatccaga aaatcttcaa
    21061 tttattttcc caacgcaggc aagtctggaa gaaagtcaat atgcactggc caattacttt
    21121 atgaagtccc ctttgggagt gtgggcaatt tgtgaccaga aaaatcaaca aatgattggt
    21181 tctattaaat ttgagaagtt agatgaaatc aaaaaagaag ctgagcttgg ctattttttg
    21241 agaaaagatg cttggtcgca aggatttatg acagaggttg ttagaaaaat ttgtcagctt
    21301 tcttttgagg aatttggctt aaaacaatta tttatcatta cccaccttga aaatgaagct
    21361 agccaaagag ttgctcttaa gtctggattt agtttgttcc gtcagtttaa gggaagtgat
    21421 cgttacacaa gaaaaatgcg ggattatctt gaatttcggt atgtaaaagg agagttcaat
    21481 gagtaagcat caggaaattc taagctattt ggaggaatta ccagtaggta aaagggtcag
    21541 tgttcgtagc atttcgaatc atctaggagt tagtgatgga acagcctatc gagctattaa
    21601 agaagctgaa aaccgtggaa ttgtggagac ccgtcctaga agtggaacaa ttcgtgttaa
    21661 atcccagaaa gttgctatag agagattaac gtttgctgaa attgcagaag tgacttcttc
    21721 tgaggttctg gctgggcaag aaggtttaga gagagagttt agtaagtttt caattggtgc
    21781 catgactgaa caaaatatct tgtcttacct tcatgatggg gggctcttga ttgtcggaga
    21841 ccgaacccgt attcagttgc tagccttgga aaatgaaaat gcagttctgg ttacaggggg
    21901 atttcaggtt catgatgatg tgcttaaact ggccaatcaa aaagggattc ctgttctaag
    21961 aagtaagcat gataccttta ccgtcgcgac catgatcaat aaagccttgt caaatgtcca
    22021 aatcaagact gatattctga cagttgagaa actttatcgc cctagtcatg agtatggttt
    22081 tctgagagag acagatacag ttaaagatta tttggacttg gttcgtaaga atcgtagcag
    22141 ccgtttccct gttatcaatc aacatcaggt cgttgttggc gttgtaacca tgagagacgc
    22201 tggtgataaa tcaccaagca cgacaattga taaggttatg tctcgtagtc tatttttggt
    22261 tgggttatcg acaaatattg ccaatgtgag tcaacggatg atcgcagaag actttgaaat
    22321 ggtaccagtt gttcgaagca atcaaacttt gcttggcgtt gtgacgcgac gagatgtcat
    22381 ggagaagatg agccgttccc aagtttcggc tctaccaact ttttctgagc agattggaca
    22441 aaagctctct tatcaccatg atgaagtagt cattacagtg gaacccttta tgctagaaaa
    22501 aaatggagtt ttggctaatg gtgtattggc agaaattctg acccacatga cccaagattt
    22561 agttgttaat agtggtcgca atctcattat cgagcagatg ctgatctact ttttgcaggc
    22621 tgttcagata gatgatatat tgcgcattca ggcacggatt attcatcata cgagacggtc
    22681 agctataatt gattacgata tttatcatgg tcaccagatt gtttcaaaag caaatgtgac
    22741 tgttaaaatt aattagaaac taggagaaaa gatgataaca ttaaaatcag ctcgtgaaat
    22801 cgaagctatg gacaaggctg gtgattttct agcaagtatt catataggct tacgtgattt
    22861 gattaagcca ggcgtagata tgtgggaagt tgaagaatat gtccgccgtc gttgtaaaga
    22921 agaaaatttc cttccacttc agattggggt tgacggtgcc atgatggact atccttatgc
    22981 tacctgttgc tctcttaacg atgaagtggc tcacgctttc cctcgtcatt atatcttgaa
    23041 agatggtgat ttgctcaaag ttgatatggt tttgggaggt cccattgcta aatctgacct
    23101 gaatgtctca aaattaaact tcaacaatgt tgaacaaatg aaaaaataca ctcagagcta
    23161 ttctggtggt ttagcagact catgttgggc ttatgctgtt ggtacaccgt ccgaagaagt
    23221 caaaaacttg atggatgtaa ccaaagaagc tatgtacaag ggtattgagc aagctgttgt
    23281 tggaaatcgt atcggtgata tcggtgcggc tattcaagaa tacgctgaaa gtcgtggtta
    23341 cggtgtagtg cgtgatttgg ttggtcatgg tgttggccca actatgcacg aagaaccaat
    23401 ggttcctaac tatggtattg caggtcgtgg actccgtctt cgtgaaggaa tggtcttaac
    23461 cattgaacca atgatcaata caggcgattg ggaaattgat acagatatga aaactggttg
    23521 ggcgcataag agcattgacg gtggattgtc atgtcagtat gaacaccaat ttgtcattac
    23581 gaaagatgga cctgttatct tgactagcca aggtgaagaa ggaacttatt aataaaaagt
    23641 gaaaagacta ctggaagttt attttgataa aaaatccagt agatcttttc ataataaaac
    23701 gcattgtatc aagtgttagg agctgatatc atgcgttttt ctgcttttaa gattttttcc
    23761 aactctgttt gtaagcgcat cataacaaag ggtctaggat tcagggctct cctcctatat
    23821 actattagta aagtaaaact aagggaggat attttagtgt cgcagtctat tgttcctgta
    23881 gagattccac aatattgtcg ttttgattct aaaaagagaa atggaattct gtttaacgtt
    23941 cgtattgcca atcttaaatt tacctttttt agattagact
//
LOCUS       DBEJHE010000029        22494 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC4 isolate 671759
            SAMN38261586-rid24793303.denovo.29, whole genome shotgun sequence.
ACCESSION   DBEJHE010000029 DBEJHE010000000
VERSION     DBEJHE010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261586
            Sequence Read Archive: SRR26833752
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 22494)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22494)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576136.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576136.1
            Genome Coverage       :: 109x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 19:48:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,067
            CDSs (total)                      :: 2,029
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 131
            CDSs (without protein)            :: 131
            Pseudo Genes (ambiguous residues) :: 0 of 131
            Pseudo Genes (frameshifted)       :: 64 of 131
            Pseudo Genes (incomplete)         :: 59 of 131
            Pseudo Genes (internal stop)      :: 46 of 131
            Pseudo Genes (multiple problems)  :: 32 of 131
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22494
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261586-rid24793303.denovo.29"
                     /strain="GPSC4"
                     /isolate="671759"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            92..3442
                     /locus_tag="ACL3EZ_001582"
     CDS             92..3442
                     /locus_tag="ACL3EZ_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000526318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HGR0393124.1"
                     /translation="MGNFSFLLKNDEYESFSKPCIEAENMIATSTVATAFMARRALEQ
                     AVHWIYSHDSYLEAPYRATLSSLVWDDDFRDIVDSELHKQIVLLIRWGNHAAHGGEIK
                     EREAILALHHLYQFVNFIDYCYSNEFVERYFDEKCLPLSANIKYRETPQSMIKLQDSL
                     PELPGFHEQMAAQSVEVQETYTEKRETAAQRQDVPFHIDQLSEAETRKLFIDIDLRLA
                     GWIFEENCRVEIAVDGLKHGSGIGYCDYVLYGKNGKILAIVEAKKASVNPEVGEVQVK
                     EYAEALEKHIGYQPICFITNGLKHYILDGPNRRQIAGFYSQEELQLVMDRRHLQKPLE
                     DISSKIRDDISGRHYQKHAIASVCEAFSNHRRQVLLVMATGAGKTRTAVSLVDILSRH
                     NWVKNVLFLADRTSLVKQAYDSFRKLLPDLSVCNFLEDKEGAQSSRMVFSTYPTMIGA
                     ISGQEEVNQRPFTVGHFDLIIIDESHRSIYQKYKSIFDYFDARIVGLTATPRQDLDKN
                     TYGFFNLENGVPTYAYDLEEAVKDGYLVAYHSIETKLKLPTDGLHYDDLSEEEKEHFD
                     SKFEDDSCEKDIDGSVFNSFVFNKSTVEIVLNELMTRGIQTASGDEIGKTIIFAKNHD
                     HAEYIRGIFNNRYPEKGSDYAQVIDYSIKHYQTLIDDFKIKEKYPQIAISVDMLDTGI
                     DVPEVVNLVFFKKVRSKTKFWQMIGRGTRLCKDLFGPEQDKENFLVFDYGDNFDYFRA
                     DPRDGEGRHIVSLTQRLFNIKVDLIRELQGLQYQEDQFARAYRQQLVSELQGRIESLN
                     ELDFRVRMVLDTVYSYRKLESWQNLTAVTSETIQKNLSLLLFDEDKEDEMARRFDLWL
                     LHIQLGQLTAKSSTVHISQVMKTARALSAIGNIPQVFEQAEIIRKVQEPEFWKEVNLS
                     DLEKIRLAIRDLLQFLDKTDRKPYYVNFEDRILSTVHETTAFLQVNDLRSYNEKVEHY
                     LKTHLDEESISKLYHNKKLTSDDMLALEKLLWEKLGSKADYQSHYENKAIPRLVREII
                     GLDRESANRIFSKFLSDENLNARQISFVKLIVDYIVENGFLETKVLTQEPFKSYGSVQ
                     LLFQHQLPVLRNIVQIIELINNRAGEAA"
     gene            complement(3948..4418)
                     /locus_tag="ACL3EZ_001583"
     CDS             complement(3948..4418)
                     /locus_tag="ACL3EZ_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001043003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HGR0393125.1"
                     /translation="MNKSEHRHQLIRALITKNKIHTQAELQALLAENDIQVTQATLSR
                     DIKNMNLSKVREEDSAYYVLNNGSISKWEKRLELYMEDALVWMRPVQHQVLLKTLPGL
                     AQSFGSIIDTLSFPDAIATLCGNDVCLIICEDADTAQKCFEELKKFAPPFFFEE"
     gene            complement(4435..6708)
                     /locus_tag="ACL3EZ_001584"
     CDS             complement(4435..6708)
                     /locus_tag="ACL3EZ_001584"
                     /EC_number="3.4.14.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008239 - dipeptidyl-peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="HGR0393126.1"
                     /translation="MRFNQYSYINFPKENVLSELKKCGFDLQNTANHKDSLETFLRRF
                     FFTYQDTNYPLSILAADKKTDLLTFFQSEDELTADIFYTVAFQLLGFAYLVDFEDSDV
                     FRKETGFPIIYGDLIENLYQLLNTRTKKGNTLIDQLVSDGLIPEDNDYHYFNGKSLAT
                     FSNQDVIREVVYVESRVDTDQKGLSDLVKVSIIRPRFDGKIPAIMTASPYHQGTNDKA
                     SDKALYKMEGELEVKLPHKIELEKPQLNLVQPQGKAELIAEAEEKLTHINSSYTLNDY
                     FLPRGFANLYVSGVGTKDSTGFMTNGDYQQIEAYKNVIDWLNGRCRAFTDHTRQRQVK
                     ADWSNGKVATTGLSYLGTMSNGLATTGVDGLEVIIAEAGISSWYNYYRENGLVTSPGG
                     YPGEDFDSLAELTYSRNLLAGDYIRGNEAHQADLEKVKAQLDRKTGDYNQFWHDRNYL
                     LNAHKVKAEVVFTHGSQDWNVKPLHVYQMFHALPTHIHKHLFFHNGAHVYMNNWQSID
                     FRESINALLTKKLLGQETDFQLPTVIWQDNTAPQTWLSLDNFGGQENCETFSLGQEEQ
                     AIQNQYPDKDFERYGKTYQTFNTELYQGKANQITINLPVTKDLHLNGRAQLNLRIKSS
                     TNKGLLSAQLLEFGQKKYLQPYPAILSARTIDNGRYHMLENLCELPFRPEAQRVVTKG
                     YLNLQNRNDLLLVEDITADEWMDVQFELQPTIYKLKEGDTLRLVLYTTDFEITIRDNT
                     DYHLTVDLAQSMLTLPC"
     gene            7055..10156
                     /locus_tag="ACL3EZ_001585"
     CDS             7055..10156
                     /locus_tag="ACL3EZ_001585"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000561528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HGR0393127.1"
                     /translation="MIAQLDTKTVYSFMESVISIEKYVRAAKEYGYTHLAMMDIDNLY
                     GAFDFLEITKKYGIHPLIGLEMTVFVDDQEVNLRFLALSSVGYQQLMKLSTAKMQGEK
                     TWSVLSQYLEDIAVIVPYFDRVESLELGCDYYIGVYPETLASEFHHPILPLYRVNAFE
                     SRDREVLQVLTAIKENLPLREVPLRSRQDVFISASSLEKLFQECFPQALDNLEKLISG
                     ISYDLDTSLKLPRFNPARPAVEELRERAELGLVQKGLTSKEYQDRLDQELSVIHDMGF
                     DDYFLVVWDLLRFGRSNGYYMGMGRGSAVGSLVSYALDITGIDPVEKNLIFERFLNRE
                     RYTMPDIDIDIPDIYRPDFIRYVGNKYGSKHAAQIVTFSTFGAKQALRDVLKRFGVPE
                     YELSAITKKISFRDNLKSAYEGNLQFRQQINSKLEYQKAFEIACKIEGYPRQTSVHAA
                     GVVISDQDLTNYIPLKYGDEIPLTQYDAHGVEASGLLKMDFLGLRNLTFVQKMQELLA
                     EIEGIHLKIEEIDLEDKETLALFASGNTKGIFQFEQPGAIRLLKRVQPVCFEDVVATT
                     SLNRPGASDYINNFVARKHGQEEVTVLDPVLEDILAPTYGIMLYQEQVMQVAQRFAGF
                     SLGKADILRRAMGKKDASAMHEMRASFIQGSLEAGHTVEKAEQVFDVMEKFAGYGFNR
                     SHAYAYSALAFQLAYFKTHYPAIFYQVMLNSSNSDYLIDALEAGFEVASLSINTIPYH
                     DKIANKAIYLGLKSIKGVSNDLALWIIENRPYSNIEDFIAKLPENYLKLPLLEPLVKV
                     GLFDSFEKNRQKVFNNLANLFEFVKELGSLFGDAIYSWQESEDWTEQEKFYMEQELLG
                     IGVSKHPLQAIASKAIYPITPIGNLSENSYAIILVEVQKIKVIRTKKGENMAFLQADD
                     SKKKLDVTLFSDLYRQVGQEIKEGAFYYVKGKIQSRDGRLQMIAQEIREAVAERFWIQ
                     VKNHESDQEISRILEQFKGPIPVIIRYEEEQKTIVSPHHFVAKSNELEEKLNEIVMKT
                     IYR"
     gene            10239..11246
                     /gene="pfkA"
                     /locus_tag="ACL3EZ_001586"
     CDS             10239..11246
                     /gene="pfkA"
                     /locus_tag="ACL3EZ_001586"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006002 - fructose 6-phosphate metabolic
                     process [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HGR0393128.1"
                     /translation="MKRIAVLTSGGDAPGMNAAIRAVVRQAISEGMEVFGIYDGYAGM
                     VAGEIHPLDAASVGDIISRGGTFLHSARYPEFAQLEGQLKGIEQLKKHGIEGVVVIGG
                     DGSYHGAMRLTEHGFPAIGLPGTIDNDIVGTDFTIGFDTAVTTAMDAIDKIRDTSSSH
                     RRTFVIEVMGRNAGDIALWAGIATGADEIIIPEAGFKMEDIVASIKAGYECGKKHNII
                     VLAEGVMSAAEFGQKLKEAGDTSDLRVTELGHIQRGGSPTARDRVLASRMGAHAVKLL
                     KEGIGGVAVGIRNEKMVENPILGTAEEGALFSLTAEGKIVVNNPHKADIELSSLNKSL
                     S"
     gene            11305..12810
                     /gene="pyk"
                     /locus_tag="ACL3EZ_001587"
     CDS             11305..12810
                     /gene="pyk"
                     /locus_tag="ACL3EZ_001587"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004743 - pyruvate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0030955 - potassium ion binding [Evidence
                     IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HGR0393129.1"
                     /translation="MNKRVKIVATLGPAVEIRGGKKFGEDGYWGEKLDVEASAKNIAK
                     LIEAGANTFRFNFSHGDHQEQGERMATVKLAEKIAGKKVGFLLDTKGPEIRTELFEGE
                     AKEYSYKTGEKIRVATKQGIKSTREVIALNVAGALDIYDDVEVGRQVLVDDGKLGLRV
                     VAKDDATREFEVEVENDGIIAKQKGVNIPNTKIPFPALAERDNDDIRFGLEQGINFIA
                     ISFVRTAKDVNEVRAICEETGNGHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMG
                     IEVPFEMVPVYQKMIIKKVNAAGKVVITATNMLETMTEKPRATRSEVSDVFNAVIDGT
                     DATMLSGESANGKYPLESVTTMATIDKNAQALLNEYGRLDSDSFERNSKTEVMASAVK
                     DATSSMDIKLVVTLTKTGHTARLISKYRPNADILALTFDELTERGLMLNWGVIPMLTD
                     APSSTDDMFEIAERKAVEAGLVESGDDIVIVAGVPVGEAVRTNTMRIRTVR"
     gene            complement(13555..13770)
                     /locus_tag="ACL3EZ_001588"
     CDS             complement(13555..13770)
                     /locus_tag="ACL3EZ_001588"
                     /inference="COORDINATES: protein motif:HMM:NF012920.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S24 family peptidase"
                     /protein_id="HGR0393130.1"
                     /translation="MEPKIRNSDYLFIKNTPQIDYNTIGIFQVDGTNYVKKLRQGYLK
                     KTQSRILRHPPRRKQPYSYHRKSCQAI"
     gene            14618..15490
                     /locus_tag="ACL3EZ_001589"
     CDS             14618..15490
                     /locus_tag="ACL3EZ_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HGR0393131.1"
                     /translation="MKKSRKLATLGICSALFLGLAACQQQHATSEGTNQRQSSSAKVP
                     WKASYTNLNNQVSTEEVKSLLSAHLDPNSVDAFFNLVNDYNTIVGSTGLSGDFTSFTH
                     TEYDVEKISHLWNQKKGDFVGTNCRINSYCLLKNSVTIPKLEKNDQLLFLDNDAIDKG
                     KVFDSQDKEEFDILFSRVPTEATTDVKVHAEKMETFFSQFQFNEKARMLSVVLHDNLD
                     GEYLFVGHVGVLVPADDGFLFVEKLTFEEPYQAIKFASKEDCYKYLGTKYADYTGEGL
                     AKPFIMDNDKWVKL"
     gene            complement(15636..15980)
                     /locus_tag="ACL3EZ_001590"
                     /pseudo
     CDS             complement(15636..15980)
                     /locus_tag="ACL3EZ_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0032196 - transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            16123..16434
                     /locus_tag="ACL3EZ_001591"
     CDS             16123..16434
                     /locus_tag="ACL3EZ_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0393132.1"
                     /translation="MELKDFTEKEQEMIKKRLTMSNISDKETTEKILALVPQDLIKRI
                     PFFVRKHATTRTIKRISIEHPELYAVAQTSGEIPEKKREELRQIITTIFEQKMNKHSI
                     K"
     gene            16438..17154
                     /locus_tag="ACL3EZ_001592"
                     /pseudo
     CDS             16438..17154
                     /locus_tag="ACL3EZ_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759776.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
     gene            complement(17284..18099)
                     /locus_tag="ACL3EZ_001593"
     CDS             complement(17284..18099)
                     /locus_tag="ACL3EZ_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000617844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HGR0393133.1"
                     /translation="MIRFLVLAGYFELTIYLHLSGKLNQYINMHYSYLAYISMVLSFI
                     LAIVQLYIWMKQVKTHSHLNSRLAKMTSISLLAIPLVIGLTFPTVSLDSQTVSAKGYH
                     FPLSEGTNLAIQTSEGTTSQYLKPDTSSYFSKSAYEKEMRTAADKYLSQDSIQITNEN
                     YMEVMEAIYDYPDEFEGKTIQFTGFVYNDPSHANSQFLFRFGIIHCIADSGVYGLLTK
                     GNTRQYENNTWISAKGKLVNHYHKELKQNLPTLEIDSFTKVDKPENPYVYRAF"
     gene            complement(18096..19001)
                     /locus_tag="ACL3EZ_001594"
     CDS             complement(18096..19001)
                     /locus_tag="ACL3EZ_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HGR0393134.1"
                     /translation="MTAFQQLPSSVLQTGAIFLSIIIEALPFVLIGSIVSGLIEVYIT
                     PDKVYHFLPRNRWGRIFFGTFVGILFPSCECGIVPIINRFLEKKVPSYTAVPFLVTAP
                     VINPIVLFATYSAFGNSFHVALLRALGSILVAVILGIFLGFFWQEPIQKENRLACHEH
                     DFSYLSSAKKVFQVFVQAIDEFFDTGRYLVFGCLFASIIQVYVPTRILTSISATPLFA
                     ILLLMILAFLLSLCSEADAFIGASLLSSFGLAPVLAFLVIGPMLDIKNILMMKNYLKA
                     RFISHFITIVTLVVLVYSLLIGVIL"
     gene            complement(19002..19133)
                     /locus_tag="ACL3EZ_001595"
     CDS             complement(19002..19133)
                     /locus_tag="ACL3EZ_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPJ_0845 family protein"
                     /protein_id="HGR0393135.1"
                     /translation="MAVKFTKRDDLDKMFEEFAKLPDLKQVTFPDDKEKKVKAEKKN"
     gene            19503..21632
                     /locus_tag="ACL3EZ_001596"
     CDS             19503..21632
                     /locus_tag="ACL3EZ_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003729 - mRNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Tex family protein"
                     /protein_id="HGR0393136.1"
                     /translation="MDKKYEKISQDLGVTLKQIDTVLSLTAEGATIPFIARYRKDMTG
                     SLDEVAIKAIIDLDKSLTNLNDRKEAVLAKIQEQGKLTKELEEAILVAEKLADVEELY
                     LPYKEKRRTKATIAREAGLFPLARLILQNIVDLEKEAEKFVCEGFATGKEALTGAVDI
                     LVEALSEDVTLRSMTYQEVLRHSKLTSQAKDESLDEKQVFQIYYDFSETVGTMQGYRT
                     LALNRGEKLGVLKIGFEHATDRILAFFATRFKVKNAYIDEVVQQSVKKKVLPAIERRI
                     RTELTEKAEEGAIQLFSDNLRNLLLVAPLKGRVVLGFDPAFRTGAKLAVVDATGKMLT
                     TQVIYPVKPASARQIEEAKKDLADLIGQYGVEIIAIGNGTASRESEAFVAEVLKDFPE
                     VSYVIVNESGASVYSASELARQEFPDLTVEKRSAISIARRLQDPLAELVKIDPKSIGV
                     GQYQHDVSQKKLSESLDFVVDTVVNQVGVNVNTASPALLSHVAGLNKTISENIVKYRE
                     EEGKITSRSQIKKVPRLGAKAFEQAAGFLRIPESSNILDNTGVHPENYAAVKELFKCL
                     DIKDLNEEAQSKLKSLSVKEMAQELDLGPETLKDIIADLLKPGRDFRDSFDAPVLRQD
                     VLDIKDLVVGQKLEGVVRNVVDFGAFVDIGIHEDGLIHISHMSRKFIKHPSQVVAVGD
                     LVSVWVKKIDTEREKVNLSLLAPNETD"
     gene            21619..22068
                     /locus_tag="ACL3EZ_001597"
     CDS             21619..22068
                     /locus_tag="ACL3EZ_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HGR0393137.1"
                     /translation="MKLTDYVKQVSLEDFGRPFIHHVQWNRRLRSTGGRFFPKDGHLD
                     FNPKVYQELGLDVFRKIVRHELCHYHLYFQGKGYQHKDRDFKELLKAVDGLRFVPSLP
                     NSNSKPIKLYRCQSCQQTYQRKRRIDTKRYRCGLCRGKLLLVNQPED"
     gene            22127..22399
                     /locus_tag="ACL3EZ_001598"
     CDS             22127..22399
                     /locus_tag="ACL3EZ_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HGR0393138.1"
                     /translation="MNSKFYKMRRNRMISGVLAGLSDKWNFDVTLVRFLFAIFTVANF
                     GLGVIIYIILASIMPTKEEIEAEMYGTGPRKRKEAQAIDDNEGWFW"
BASE COUNT         6934 a         3931 c         4841 g         6788 t
ORIGIN      
        1 aatttgcttg tgagatagct ataaaagtgt ggagaaatag cttgaaattt agtataatat
       61 agctaaacta tttgtttaaa gtgagaaaaa aatgggaaat tttagctttc ttttaaaaaa
      121 tgacgaatat gaatcttttt caaaaccttg cattgaagct gagaatatga ttgctacatc
      181 aactgtggct actgccttta tggcgcgtcg tgctttagag caggctgtcc attggatata
      241 tagtcacgat tcatatttag aagctcccta tcgtgctact ctatcttctt tagtatggga
      301 tgatgatttt agggatatcg tagattctga actccacaag cagatagttc tgttgattcg
      361 gtggggaaac catgctgctc atggtggtga aattaaggaa cgagaagcga ttttagcttt
      421 gcatcatttg tatcagtttg ttaattttat cgattattgt tacagcaatg agtttgtgga
      481 gcgttatttt gatgagaagt gcttaccact ttcagcaaac atcaaatacc gagaaactcc
      541 acaatctatg ataaagttac aagacagttt accagaactg cctggttttc atgaacagat
      601 ggctgctcag tccgtagaag ttcaagagac ttatactgaa aaacgtgaga ctgcagcgca
      661 acggcaagat gtgcctttcc atattgatca attatctgag gcagagacaa gaaagctctt
      721 tattgatatc gatctccgtt tagcaggatg gatatttgaa gaaaactgtc gtgttgagat
      781 agccgttgat ggtctcaagc acggttcagg aattggttac tgtgactatg tactttatgg
      841 taaaaatggg aaaattttag cgattgtaga ggctaaaaaa gcctctgtca atccagaagt
      901 aggggaagta caggtcaaag aatatgctga agctcttgag aaacatatcg gctatcagcc
      961 aatttgcttt attacaaatg gcttgaagca ctatatactt gatggtccga accgccgcca
     1021 gattgcaggc ttttactctc aagaagaatt gcaattagtg atggatagac gtcatcttca
     1081 aaaaccactt gaggatattt ctagtaaaat tagggacgat atttccgggc gtcactacca
     1141 aaaacatgcc attgcaagcg tttgtgaagc tttctctaat catcgtagac aggtactttt
     1201 ggttatggca actggggctg ggaaaactcg tacagcagtt tctctagttg atatcttatc
     1261 acgtcataac tgggtaaaaa acgttctctt cttagccgat agaacttcct tggttaagca
     1321 agcctatgat tcgtttagaa aattactccc agatctttcc gtttgtaact tcttagaaga
     1381 taaagaagga gctcaatcaa gtcgcatggt cttttcaact tatccgacca tgattggagc
     1441 gattagtggt caagaagaag taaatcaacg ccctttcact gttgggcatt ttgaccttat
     1501 cataattgac gaatctcacc gttctattta tcagaaatac aagtccattt ttgattattt
     1561 tgatgcaaga attgtaggct taacagctac tccgcgtcaa gatttagata aaaacaccta
     1621 tggattcttt aatttggaga atggggttcc aacatatgca tatgatttgg aagaggctgt
     1681 taaagacgga tatttagtag cctatcattc tatcgaaacc aaactgaaac tacctacgga
     1741 tggtctacat tatgatgatt tgtccgaaga agaaaaggaa cattttgata gcaaatttga
     1801 agacgatagc tgtgaaaaag atattgatgg gagtgtattt aattcctttg ttttcaataa
     1861 aagtacagta gaaattgttt taaatgaact catgacaaga ggaattcaga cagcctcggg
     1921 tgatgaaatt ggtaaaacta ttatttttgc taaaaatcat gatcatgcgg aatatatcag
     1981 aggtattttt aacaaccgct atcctgaaaa agggagcgac tatgctcagg tgattgatta
     2041 tagtattaag cattatcaga ccttgattga tgattttaaa attaaggaga agtatcctca
     2101 aattgcgatt tctgtcgata tgttagatac aggtattgat gtaccagagg ttgttaattt
     2161 agtcttcttc aagaaagtac gctctaaaac taagttttgg cagatgattg gtcgaggaac
     2221 ccgtctatgt aaagatttat ttggacctga gcaggataag gaaaacttct tggtatttga
     2281 ttatggggac aattttgatt attttcgtgc agatccaaga gatggagagg gtcgtcacat
     2341 tgtttcgttg actcagcgtt tatttaatat caaagtggac ttgattcgag aacttcaggg
     2401 actccaatac caagaagatc agtttgcgag agcataccgt cagcagcttg tctcggaact
     2461 tcaaggtcgt atagagagct taaatgagtt ggacttcagg gttcgtatgg ttttagatac
     2521 agtttatagc tataggaaat tggaaagttg gcagaatcta actgctgtta caagtgaaac
     2581 cattcaaaaa aatctctctc tgcttttatt tgatgaagat aaagaagatg agatggcgag
     2641 gagatttgat ttgtggttgc ttcatattca gttggggcaa ctgacagcta aatcttccac
     2701 tgttcatatt tcccaagtga tgaagacggc tagagctctt tctgctattg gcaatatccc
     2761 gcaggttttt gagcaggctg aaattatcag gaaagtacag gagcctgaat tttggaaaga
     2821 agttaacttg tctgatttgg aaaaaattcg tcttgctatt cgagatttat tacagttttt
     2881 ggataaaaca gaccgtaaac cctactatgt taactttgaa gatcgtatac tctccactgt
     2941 tcacgagacc acagcatttt tgcaggtcaa cgatcttcgg tcttacaatg aaaaagttga
     3001 gcattatttg aaaactcatc tggatgagga gtccatttct aagctatacc ataataaaaa
     3061 gttgacatct gatgatatgc ttgcacttga aaaattgctt tgggaaaaat taggtagtaa
     3121 agcagactac caaagtcatt atgaaaataa ggcaattccg agattggttc gtgagattat
     3181 tggcttagat agagagtctg ccaatcgtat tttttctaaa tttttgtcgg atgagaatct
     3241 taatgccagg cagatttcat ttgtaaaatt gattgtagac tacattgtag aaaatggttt
     3301 tttagagacg aaagtgttaa cgcaagagcc gtttaaatct tatggttctg ttcaactact
     3361 cttccaacac caactaccag tacttcgtaa tattgttcaa atcattgaac ttatcaataa
     3421 tcgagctgga gaagcggctt aaattctaaa gtgattgcca tgctgagact catttaaaat
     3481 taaaaagagt agaaatttat gctatatatg agaagtttta ttaggaagaa tgtcatcgtt
     3541 ttcctagaat acagtatcag ttgttaagtg gttgataaat ttcaaagtag atacttgtac
     3601 cacgatgttt gttgatcgag ttattaacaa aagagctact ttgattttaa agaaatagaa
     3661 aacaaaaagc cgagcaagaa ttcaattgca ggagaaaatg aaataatact caatgaaaat
     3721 caaagagcaa actaggaaac tagctgcagg ctgctcaaaa cactgttttg aggttgtaga
     3781 tggaagctga cgcggattga agagattttc gaagagtata aatcttccta ggataaagca
     3841 aaacgcatag tatcaagggt tttcaacact tgatactatg cgttttctga tgttaaagac
     3901 tttctaccag gttttttaaa agcataattg ttagttgtag tcatttatta ttcttcaaag
     3961 aaaaatggtg gggcgaattt tttcagttct tcaaagcact tttgagcagt atctgcatct
     4021 tcacagatga taagacagac atcattacca caaagggtag cgatagcgtc agggaagctc
     4081 aaagtatcaa tgatagaacc aaaggattga gccagtccag gaagggtttt tagtaggact
     4141 tggtgttgaa ctgggcgcat ccagacaagg gcgtcttcca tgtagagttc gagacgtttt
     4201 tcccattttg agatggaacc attgttaaga acataataag cgctatcttc ttcgcggact
     4261 tttgataggt tcatattttt gatgtcgcgt gagagggttg cctgggttac ttgaatgtcg
     4321 ttctcagcaa gaagggcttg caactcagcc tgtgtatgaa tcttgttttt tgtgataaga
     4381 gcgcgtataa gttggtggcg gtgttctgat ttattcataa taatgtaact ccttttagca
     4441 aggtaaggta agcatggact gagcgaggtc gacagtcaag tggtagtctg tattgtcacg
     4501 gatggtgatt tcaaagtcag tagtatagag gactaaacgg agagtgtctc cttcttttag
     4561 cttgtaaata gttggctgca gttcaaattg aacgtccatc cattcatctg cagtaatatc
     4621 ctctactaac agtaaatcat ttctattttg taaattaagg taaccttttg tcacgactcg
     4681 ttgtgcctct ggtctaaatg gcaattcaca gagattttcc aacatgtgat agcgaccgtt
     4741 gtcaatggtt ctagcactta aaatagctgg ataaggttgt aggtatttct tttgcccaaa
     4801 ttctagcagt tgggcagata agagcccctt gtttgtactg gatttgatac gaagattgag
     4861 ctgagcgcga ccgtttaggt ggagatcttt agtcacagga aggttaatag taatctgatt
     4921 ggctttccct tgatagagct ctgtattgaa ggtttggtat gtcttaccat agcgctcaaa
     4981 atccttatct gggtactggt tttgaatagc ttgctcttct tgaccaagtg agaaggtttc
     5041 acagttttct tgcccaccga agttatcaag tgataaccaa gtctgtggag ctgtattgtc
     5101 ctgccagata acagtaggaa gttgaaagtc tgtttcctgt cctagtaatt tcttggtcaa
     5161 taaggcattt atggactcac ggaagtcaat tgattgccaa ttgttcatgt aaacatgggc
     5221 accattatgg aaaaagagat gcttgtgtat atgagtagga agagcatgga acatctggta
     5281 aacatgaagt ggtttgacat tccaatcctg agaaccatga gtaaagacaa cctctgcctt
     5341 tactttatgg gcattgagca gataattgcg gtcatgccaa aactgattgt agtccccagt
     5401 ttttcggtct agctgagctt tcactttttc taagtcagct tggtgagctt cattgccacg
     5461 gatatagtcg ccagctaaga gattacgaga ataggttaac tcagcaaggg agtcaaagtc
     5521 ctcacctgga taaccacctg ggctagtcac cagaccgttt tcacggtagt agttgtacca
     5581 tgatgaaatt cctgcctcgg caatgataac ttctaaacca tcgactcctg tagtcgcaag
     5641 accattggac atggtaccta gataggaaag tcctgttgta gcaacttttc cgtttgacca
     5701 atcagccttg acttgacgct ggcgcgtgtg atcagtaaag gcacggcaac ggccgttaag
     5761 ccaatcgatg acatttttat aagcctcgat ttgctggtag tctccattag tcatgaaacc
     5821 tgtcgagtct ttggtaccaa cacctgagac atagagattg gcaaagcctc tcggaaggaa
     5881 gtagtcgttt agtgtatagc tagagttgat gtgagttagc ttttcctcag cctctgctat
     5941 aagctcagct ttaccttggg gttggacgag atttagttga ggtttctcta gctcaatctt
     6001 gtgaggaagt ttaacctcaa gctcgccctc catcttgtag agagccttgt cactagcctt
     6061 gtcattggtt ccctgatgat aagggctggc tgtcatgatg gcagggattt ttccatcaaa
     6121 acgagggcga ataatgctaa cctttactag gtctgatagc cctttttggt cagtatcgac
     6181 acgagactca acgtaaacga cttcacgaat gacatcctgg ttagaaaaag tagccaaact
     6241 cttgccgtta aagtagtggt agtcattatc ctccggaata agaccatcac taacaagttg
     6301 gtcgataaga gtatttcctt ttttggtgcg agtattgagt aactgataga gattttcaat
     6361 caagtcacca tatataatgg gaaatccagt ttctttacga aaaacgtcac tatcttcgaa
     6421 gtcaaccaaa taagcaaagc ctaaaagttg aaaagcaaca gtataaaaaa tatctgctgt
     6481 cagttcatct tctgattgaa aaaatgtcag caggtctgtt tttttatcag ctgctaggat
     6541 agaaagtggg tagttggtgt cttgataagt gaaaaagaaa cgacgtaaaa aggtttcaag
     6601 tgagtctttg tgattggctg tattttgtaa atcaaagcca cattttttta gttcagataa
     6661 gacattttct tttggaaaat tgatataact atattgatta aaacgcatag aacctccata
     6721 tagaatgaca gttaaggtta ttatatcaaa aaaaaagcag aaagggaatt gttaacttca
     6781 aaaggaaata atccaataaa aatgaataaa gtactaaatt caatatagag aacagagtaa
     6841 caataagaat aaatagatag ggtataaaag ttctaggaga tttatattat atgctttcta
     6901 tttttatata caatatagta taaatataaa aatgatgaca aaaatacaaa tgaatagaaa
     6961 ataaattagt aagctgatga aatttttctc aagagaagcc atttataggt gaaaatggta
     7021 taatatagtg agaaggatag aggagaagtg taaattgatc gcacaactag atacaaaaac
     7081 agtctatagt tttatggaaa gcgtcatttc gatcgaaaag tatgtgagag cagctaaaga
     7141 atacggctac actcatttgg ctatgatgga tattgacaat ctttatggcg ctttcgactt
     7201 tctagagatt acaaaaaaat acggcattca tcctttgata gggcttgaaa tgacagtgtt
     7261 tgtagatgat caggaagtga atttgcgctt tttagctcta tctagtgtgg gctatcagca
     7321 gttgatgaag ctttcgacag ccaagatgca gggggagaaa acttggtcag tcctgtccca
     7381 gtacctggag gatatcgcgg tcattgtgcc ttattttgat agagttgagt cgttagaact
     7441 aggctgtgat tactatatag gggtttatcc agaaacacta gcaagcgaat ttcatcatcc
     7501 tatcttacct ctttatcggg tcaacgcttt tgaaagcagg gatagagaag ttcttcaagt
     7561 tttaacagcg attaaagaaa atctaccgct cagagaagtt cccttgcgtt cgagacaaga
     7621 tgtctttata tcagcaagtt ctttagagaa actattccaa gagtgttttc cgcaagcttt
     7681 ggacaattta gaaaagctta tttcaggcat ttcttacgac ttggatacta gtctgaaact
     7741 gcctcgtttt aatccagcta gaccagcagt agaggagttg agagagcgtg ctgaactggg
     7801 gcttgttcag aaggggttga ctagtaaaga atatcaagat agactagacc aagaattgtc
     7861 tgttattcat gatatgggct ttgatgatta tttcttggtt gtttgggatt tgttgcgttt
     7921 tggacgatcg aatggctatt atatgggaat gggaaggggt tctgcagtag gcagtttggt
     7981 ttcttatgcc ttagacatca cggggattga cccagtagag aaaaatctga tttttgaacg
     8041 ctttcttaat cgtgaacgct ataccatgcc tgatattgat attgatatcc cagatattta
     8101 tcgtccagat tttatcagat atgttggtaa taaatatggt agtaaacatg cggcacaaat
     8161 cgttactttt tcaacctttg gagccaagca agctcttcga gatgtcttga aacgctttgg
     8221 tgtgccagag tatgaattat ctgcaattac taagaaaatc agttttcgtg acaatcttaa
     8281 gtcggcctat gagggcaatc tccagtttcg tcagcaaatc aatagtaagt tagaatacca
     8341 aaaagctttt gagattgctt gcaagataga gggctatcca agacaaacct ctgtccatgc
     8401 ggctggtgtt gtaattagtg accaagattt aaccaactat attcctctaa agtatggtga
     8461 tgaaattcca ctgactcagt atgatgctca tggagttgag gctagcggac ttttgaagat
     8521 ggactttctg ggactacgaa atttgacctt tgtccagaag atgcaagagt tgcttgctga
     8581 aatagaaggt attcacctta aaattgaaga aatagatttg gaagacaaag aaacgttagc
     8641 tttatttgcc tctggaaata caaaaggtat ctttcaattt gagcaaccag gtgccattcg
     8701 tctgcttaag cgtgtgcaac cagtctgttt tgaagatgtc gtcgcgacta cttctctaaa
     8761 tcgaccgggt gctagtgact atatcaataa ttttgtggca agaaagcatg ggcaggaaga
     8821 agtgactgtt ctggatccag tactggagga tattttggct ccaacctacg gcataatgct
     8881 ctatcaggag caggttatgc aggttgccca gcgatttgcc ggatttagtc ttgggaaagc
     8941 cgatattttg cgtcgggcta tggggaaaaa ggatgcctct gccatgcatg agatgagggc
     9001 ttcctttatt caaggttcat tagaagctgg tcatactgtg gaaaaagcag agcaggtctt
     9061 tgatgttatg gagaagtttg caggttatgg ttttaacagg tcacacgcct atgcctactc
     9121 agccttggcc ttccagttgg cttattttaa aacacattat ccagccattt tttatcaggt
     9181 catgttaaat tcttccaaca gtgattactt aatagatgca cttgaagcag gttttgaagt
     9241 agcctctcta tccatcaaca ccattcccta tcacgataaa attgccaaca aggccatcta
     9301 tctaggtttg aaatccatta aaggagtcag taatgattta gctctctgga ttattgaaaa
     9361 tagaccttat tctaacattg aagattttat agctaaatta cctgagaatt atctgaaact
     9421 tcctctgcta gaacctttgg taaaagttgg tcttttcgat tcatttgaaa aaaatcgtca
     9481 aaaagtattt aataatttag ctaatctatt tgaatttgtg aaagagttgg gaagtttgtt
     9541 tggagatgct atttatagtt ggcaggaatc ggaagattgg acggaacaag aaaaatttta
     9601 tatggaacaa gagcttttag ggataggtgt cagcaaacat ccactacaag ctattgcaag
     9661 taaggctatt tacccgatta ccccaatcgg aaatttgtca gaaaatagct atgctattat
     9721 cttggttgaa gttcagaaaa taaaagtgat tcgtaccaaa aagggtgaaa atatggcctt
     9781 cttacaggca gatgatagta agaaaaaatt ggatgtcact ctcttttcag acttatatcg
     9841 tcaggttgga caggaaataa aagagggagc cttctactat gtaaaaggaa aaatacaatc
     9901 acgtgatggc cgtctgcaaa tgattgcaca agaaataaga gaagcagttg ctgaacgctt
     9961 ttggatacag gtgaaaaatc atgaatcgga tcaagaaatt tcacgcattt tagaacaatt
    10021 taaaggccca atcccagtca tcatccggta tgaagaggaa cagaaaacca tcgtttctcc
    10081 ccatcatttt gtagctaaat ccaatgaatt agaggagaaa ttgaatgaaa tcgttatgaa
    10141 aacgatttat cgctaaaaat acggaaaata gaagaatttt aaaatcaaat gtgatataat
    10201 caagaagaat gttaaaagaa aaaggagcat aaaccaatat gaaacgtatt gctgttttga
    10261 ctagtggcgg agacgcacct ggtatgaacg ctgccatccg tgcagttgtt cgtcaagcaa
    10321 tttcagaagg aatggaagtg tttggtatct atgacggata tgctggtatg gttgccggtg
    10381 aaattcatcc cctagatgca gcttcagtag gggacatcat ttctcgtggt ggtacttttc
    10441 ttcactcagc tcgttatcca gagttcgctc aacttgaagg gcaacttaaa gggattgagc
    10501 aattgaaaaa acacggaatt gaaggtgtag ttgttatcgg tggtgacgga tcttaccacg
    10561 gcgctatgcg tttgactgaa catggcttcc cagctattgg tcttccaggt acaatcgata
    10621 acgatatcgt tggtactgac tttacaatcg gttttgacac agcggttact actgccatgg
    10681 acgctatcga taagattcgt gatacatcat caagtcaccg tcgtactttt gtaatcgaag
    10741 ttatgggacg taacgctggt gatatcgctc tttgggctgg tattgcaact ggtgctgatg
    10801 aaatcatcat ccctgaagca ggcttcaaga tggaagatat cgtagcaagc atcaaagctg
    10861 gttatgaatg tggtaaaaaa cacaatatca tcgtcttagc tgaaggtgtg atgtcagcgg
    10921 ctgaatttgg tcaaaaactt aaagaagctg gagatacaag cgaccttcgt gtaacagaac
    10981 ttggacatat tcaacgtggt ggttctccaa ctgcgcgtga ccgtgttttg gcgtcacgta
    11041 tgggtgcaca tgctgttaaa cttcttaaag aaggtatcgg tggtgttgcg gttggtattc
    11101 gtaacgaaaa aatggttgaa aatccaattc ttggtactgc agaagaaggg gcattgttta
    11161 gccttactgc agaaggtaag attgtggtta acaacccgca caaagccgat attgagctat
    11221 ctagcttgaa taagagcttg tcataattta caatttagtt aataagacca aaaaggtcat
    11281 atatataaag gagtcacaaa aatcatgaac aaacgtgtaa agatcgttgc aactttgggt
    11341 cctgcggtag aaatccgtgg tggtaaaaaa ttcggtgagg acggatactg gggtgaaaaa
    11401 cttgatgttg aagcttcagc taaaaacatt gctaaattga ttgaagctgg tgctaacaca
    11461 ttccgattca acttctcaca cggcgaccac caagaacaag gtgagcgtat ggcaactgtt
    11521 aaacttgcgg aaaaaattgc aggtaaaaaa gttggtttcc ttcttgatac aaaaggacct
    11581 gaaatccgta cagaattgtt cgaaggtgaa gctaaagaat attcatacaa aactggtgaa
    11641 aaaattcgtg ttgcaactaa acaaggaatc aaatcaactc gtgaagtgat tgcgttgaac
    11701 gttgctggtg ctcttgatat ctatgatgat gttgaagttg gtcgtcaagt tttggttgac
    11761 gatggtaaac ttggtcttcg tgtggttgct aaagatgatg caactcgtga atttgaagtt
    11821 gaagttgaaa acgatggtat catcgctaaa caaaaaggtg tgaacatccc taacactaaa
    11881 attcctttcc cagctcttgc tgaacgcgat aacgacgata tccgtttcgg tcttgaacaa
    11941 ggtatcaact tcatcgcaat ttcattcgta cgtactgcaa aagatgtgaa cgaagttcgt
    12001 gcaatctgtg aagaaactgg aaacggacat gttcaattgt tcgctaaaat cgaaaaccaa
    12061 caaggtatcg ataacttaga tgaaatcatc gaagcagctg atggtattat gattgctcgt
    12121 ggtgatatgg gtatcgaagt accgttcgaa atggttccag tttatcaaaa aatgattatc
    12181 aagaaagtca atgctgcagg taaagttgtt atcactgcaa caaacatgct tgaaacaatg
    12241 actgaaaaac cacgtgcaac tcgttcagaa gtatcagacg tattcaacgc tgttatcgac
    12301 ggaactgacg ctacaatgtt gtcaggcgag tctgcaaacg gtaaataccc actcgagtca
    12361 gtaactacaa tggctacaat cgacaagaac gctcaagctc ttcttaatga atacggacgt
    12421 cttgattcag attcatttga gcgtaactct aagacagaag taatggcttc tgctgttaaa
    12481 gatgctacta gctcaatgga tatcaaattg gttgtaactc ttactaagac aggtcatact
    12541 gcacgtttga tttctaaata ccgtccaaat gctgacatct tagcattgac atttgacgaa
    12601 ttgacagaac gtggcttgat gttgaactgg ggtgttatcc caatgttgac agatgctcca
    12661 tcttcaactg acgatatgtt cgaaatcgct gaacgtaaag cggtagaagc aggtctcgtt
    12721 gagtcaggcg atgatatcgt tatcgttgct ggtgtgccag taggagaagc tgttcgcaca
    12781 aacacaatgc gtatccgcac agtacgttaa gaaaaatata aaaacctatc atatccagct
    12841 ttctagcctg tatgatgggc tctttttttg tccagggggc aaaaaggggg caaaactttc
    12901 ataatggatt gatactcttc gaaaatcaaa ttcaaaccac gtcagcgtcg ccttaccgta
    12961 tatatgttac tgacttcgtc agttctatct acaacctcaa agcagtgctt tgagcaacct
    13021 gcggctagct tcctagtttg ctctttgatt ttcattgagt atgaaataag atatgcataa
    13081 attgattaga aagtcaaatg aatttctaca aatgttttag caatcgcaat ctacttgtct
    13141 agattcgatc tgatatattt tcgatttaat gatatggtat ttaaaacctc caaagtagct
    13201 tgctccattc ttttacctac gtgagtctag atgttattta ctgttttagc gtttttgtgt
    13261 tctactctaa ccattatagc attcttctca gctagtgtac taaggagtgt gtgcctgaaa
    13321 atatgggaac taaggggctg gtttatcggt ttctctagtt tagtatttgc cttttgcaaa
    13381 gtgatcttaa atgcctttct ctaaatttac atatcactat tgtttaacaa aatctaatct
    13441 attttaggtc acttattctt tttttgaaat gtagaatgaa ctttttcaaa gtttttcgaa
    13501 tcttttaaaa tctgtttgtt ttatatcgcc attctccccc ttttttaatt ctccctatat
    13561 agcctgacaa cttttccgat ggtacgaata tggttgcttt cgtctaggtg gatgtcggag
    13621 tattcgggat tgagtttttt tgaggtagcc ttggcggagt ttcttgacat agttagtgcc
    13681 gtctacttgg aagatgccga tggtattata gtcaatctgt ggggtattct tgataaatag
    13741 gtagtcgctg tttcttatct ttggctccat ggacttgctg acgacataag cgattgggtc
    13801 gtagtcgtct gggataatgg aaactccata actaaatcgt cgtcctgcat caagcggcta
    13861 cctgcagaga taaactacct aacacgagag taagtagtct gtctgtagtc gtccagtctg
    13921 atgattttta cgatacttcg tttttctgat catacagttg cctctcggca taggtcagaa
    13981 ctttaccttg tctgggtggt gcccgttggt cgtagataga ttggatatcg ctaggagaat
    14041 ccttttgaac tggaggaaag agggcatcaa tcaagctact gaatacttta actaagtcaa
    14101 atatagtatt tttcttagta gacctaaccc ttttttcata atttctaatg gtgtttttac
    14161 ttatacctat cttagtaccc aattcttatt gagtccaacc attactagtc tatattgttt
    14221 tatagttgat tgagtttgga atagtacgct gtagctgcta aaacatttct aggaattaat
    14281 ttgcctttcc taatagagtt gttcatatct tatttcaatc tactatattt ttcacctcta
    14341 acaatcgcaa tctcttcttt atccatgaac gaaaacgctt tctatctttg taagtaaagc
    14401 atcacacgaa atccacgaaa atgaaaacct ttgttgtgtt ttcgtaaaaa atttgttgac
    14461 agagcacgaa acgcctacta taattaaatc aagtttaagg aaataacaaa aaaacaaatc
    14521 ggagggaaag acgatgaaca cattaaatga gaaagtaatc aatatctgta aagcagtagt
    14581 taaagaaact ttaatccaag acatttagga gaaagaaatg aagaaatcaa gaaaattagc
    14641 cacattagga atctgttcag ccttgttttt aggcttggct gcttgtcaac aacaacatgc
    14701 tacttctgag gggacgaatc aaaggcaaag cagttcagcg aaagttccat ggaaagcttc
    14761 atacaccaac ctaaacaacc aggtaagtac agaagaggtc aaatctctct tatcagctca
    14821 cttggatcca aatagtgttg atgcattttt taatctcgtt aatgactata ataccattgt
    14881 cggctcaact ggcttatcag gagatttcac ttcctttact cacaccgaat acgatgttga
    14941 gaaaatcagt catctctgga atcaaaagaa gggcgatttc gttgggacca actgccgtat
    15001 caatagttat tgtcttttga aaaattcagt caccattcca aagcttgaaa agaatgacca
    15061 gttgcttttc ctagataatg atgcgattga taaaggaaag gtctttgatt cacaagataa
    15121 ggaagagttt gatattctat tttcgagagt tccaactgag gcaactacag atgtcaaggt
    15181 tcacgctgaa aagatggaaa cattcttctc acaatttcaa ttcaatgaaa aagctcgaat
    15241 gctgtctgta gtcttgcacg acaatctgga tggcgagtat ctgtttgtag gccacgttgg
    15301 ggtcttagta cctgctgatg acggtttctt atttgtagag aaattgactt tcgaagagcc
    15361 ctaccaagcg attaaatttg ctagtaagga agattgctac aagtatttag gcaccaagta
    15421 tgcggattat acaggcgagg gactggctaa gccttttatc atggataatg ataagtgggt
    15481 taaactttaa tagtgttatg atatgacagt aatcttagga tttttatttc tatttttgat
    15541 gagttggtgg gttatttcaa tcgttaatag ccagaaacca cgcaaaaatg aaacatttat
    15601 tggctatatc caaagatacg atattgatgg gaatggctat caatcattac cgtgtcctca
    15661 gaactgagag gagttcttga aatcgtaaaa ctactttgaa caagagttac ttcaacccat
    15721 tggctccgac ggattaagtt gctttcgtga acaccaaaat cagctgcaat ttcttcataa
    15781 gtgcggtatt ctcgcacata ttgaagagtg gccataagaa ggtcttctag gcttaattta
    15841 ggttttcgtc ccccttttgt gtgtttaagt tgataagcag tttttaatac agctaacatc
    15901 tcttcaaaag tggtgcgctg aacaccaaca agacatttaa atcgtgcatc agttagttgc
    15961 ttacttgctt cataattcat agaactacta taccatattt tgtttcgcag gaagtctaat
    16021 gctaaaatct tatcagtgag aagatttctt aaagtttatt ctttgtagtt tcatctgtat
    16081 tagtacataa tttaacttag agaaaatagg aggactaatc gaatggaatt aaaagatttt
    16141 acagaaaaag aacaggaaat gattaagaaa aggcttacaa tgtctaatat tagtgacaaa
    16201 gaaactactg agaagattct ggcgctagta ccacaagact tgattaagcg aatcccgttt
    16261 tttgtcagaa aacatgctac aacacgtacg attaaacgca tttcaattga acaccctgaa
    16321 ctctacgctg tagctcaaac aagtggtgag attccagaaa aaaaacgcga agaattgcgt
    16381 cagattatca caactatctt tgaacaaaag atgaataagc atagtattaa gtagagaatg
    16441 aaaaaatatt ttattggcgg tttgggaagc aatgcctatc atagcaagga ttttctttaa
    16501 gaactagatt cgcaggtcta ttttctaaat ccatatgaaa agcatcttcg agatgaaaca
    16561 gaattgaaat catggtttaa aaatgagatt gtagaggaag aatctatctg tctgataggt
    16621 cattctattg gaggcgattt agctcgttat ttcgcatcgg aatttgaaga agtaaagaaa
    16681 ctgattcttt tggatggtgg ctatctagat ttagataaga ttttaccttt ggatacagag
    16741 ttagaggaaa ctaaaaatta tatcaaatct caaattattt cggacttaga tgttcttact
    16801 tctaaagaaa aatctgaagc aaagcattgg tcagaaaata tggagaaagc tgtaagacag
    16861 tcctatcact ggaatgttga gtataataga tatgagttgg ctataaatta tgaaaatata
    16921 gaagcgatac tccgcctacg gagaaaaata caagctttta agagagaagt gggagatacc
    16981 ttgtttatta gtcctcgcta tcctaatgaa gctacatgga gagaggaagc cctaaaagaa
    17041 ttgccagact attttgatac tattttttta gaaaactttg gccatgagct ttatactcaa
    17101 gcacctaaag aaatcgctag tctaatgaat gagtggctcg cttattttct atgagctact
    17161 tgtattgctg gaaatggtat aagatgaaaa tctacaagtc actaattttc atataaccaa
    17221 aaaacgaaca ggctcttttt ctgttattca gaagagaact tgttcgtttt tatcttgatt
    17281 ttcttaaaaa gctctatata catagggatt ttctggttta tcgactttgg taaagctgtc
    17341 gatttccaag gttggaaggt tttgtttgag ttctttatgg tagtgattga ccagttttcc
    17401 tttggctgaa atccaagtgt tgttttcata ctgccgggta ttgcccttgg tcagcaatcc
    17461 atagacacca gaatctgcga tacagtggat aatgccgaat cggaacagaa attgactatt
    17521 ggcatgactg gggtcgttat agacaaagcc tgtaaactgg attgtcttgc cctcaaactc
    17581 atctggatag tcgtagatag cctccatgac ttccatatag ttttcattag tgatctgaat
    17641 gctgtcttgg gataagtatt tatccgccgc cgttcgcatt tccttttcat aggctgattt
    17701 tgaaaaataa gaactagtat ctggtttcaa atattggctt gtcgtccctt cgcttgtctg
    17761 aatagccaga ttcgttcctt ccgatagagg gaaatgatag cctttagctg aaacagtctg
    17821 agaatccaag ctaacagttg ggaaagttaa gccgatgaca agtggaatag ccagaagaga
    17881 aatactcgtc atcttggcca atcggctgtt cagatgactg tgggttttga cttgcttcat
    17941 ccagatatac aattgaacga tagccaagat aaaagaaagc accatggaga tataggccag
    18001 ataggaatag tgcatgttga tgtactggtt tagtttgccc gacagatgga ggtaaatagt
    18061 cagttcaaaa tagccagcta aaactaaaaa tcgaatcata ggatgactcc aatcaagaga
    18121 gaatagacta agacgacaag agttacaatt gttatgaagt gactgataaa tcgtgctttc
    18181 aagtaatttt tcatcatgag aatatttttg atatccagca ttggaccaat gacgagaaag
    18241 gccagaactg gtgccaaacc gaaactcgag agaagagaag cacctataaa ggcatccgcc
    18301 tcactacaga gcgaaagaag aaaggctaaa atcatcaaga gcaggatggc aaaaagaggg
    18361 gtcgcactga tagaggtcag aatccgagtc ggaacgtaga cctgtattat agaagcaaag
    18421 aggcagccaa ataccaaata acgccccgta tcaaaaaatt catcaatggc ctgcacaaag
    18481 acttgaaaaa ctttttttgc agaactcaag taagaaaaat catgctcatg acaagccaga
    18541 cgattttctt tctgaatcgg ttcttgccag aaaaatccta gaaaaattcc tagtattaca
    18601 gccacaagaa tggaacccag agctcgtaat agggcgacat ggaaggagtt gccaaaggca
    18661 gaataggtcg caaaaagaac aatgggattg ataacaggtg ctgtcacaag aaaaggaacg
    18721 gccgtgtaac ttggaacctt tttttccaga aaacgattga tgatggggac gattccacat
    18781 tcacaagaag ggaaaagtat accgacaaag gtcccaaaaa agattctccc ccaacgattt
    18841 cgagggagaa aatgataaac cttgtcaggt gtgatataaa cttcaatcag ccccgagaca
    18901 atgcttccta tcagaacgaa gggaagggct tcaatgataa tggagagaaa aatggctcca
    18961 gtttgaagta cactagatgg gagttgttga aaagcagtca tctagttttt cttttctgct
    19021 ttgacttttt tctctttgtc atcagggaaa gtaacttgtt tcaaatcagg gagtttagca
    19081 aactcttcaa acatcttgtc caagtcgtct cgttttgtaa atttgacagc cataggtgta
    19141 cctcgattct aaattctacc tctattatac tattattttg cggaaaaggg agttttttaa
    19201 tttgttttcg atagttgata ctcttcgaaa atctcttcaa accacgtcag cttcgcctta
    19261 ccgtagtacg gttactgact tcgtcagttc tatccacaac ctcaaaacag tgttttgagc
    19321 tgacttcgtc agttctatcc acaacctcaa aacagtgttt tgagctgact tcgtcagtct
    19381 tatccacaac ctcaaaacag tattttgagc agcctacggc tagcttccta gtttgctttt
    19441 tgatttttat tgagtatgaa aaggattgga gaaagccttc cagcttgtgg tataatagat
    19501 ttatggataa aaaatatgaa aaaatctctc aggatttggg agtgacgtta aagcaaattg
    19561 ataccgttct aagtttgaca gctgaagggg cgactattcc ctttatcgcg cgttatcgca
    19621 aggacatgac tggtagtctg gatgaggtgg cgattaaggc tattattgat ttggataaaa
    19681 gtctgacaaa tctcaatgac cgtaaggaag ctgtcttagc taagattcaa gaacaaggta
    19741 agttgaccaa ggaattggaa gaagctatct tagttgccga aaaattagca gacgttgaag
    19801 aactctatct tccttataag gaaaagcgtc gtaccaaggc aaccattgcc cgtgaagctg
    19861 gactctttcc tcttgctcgt ttgattttgc agaatatagt tgacttagag aaagaagctg
    19921 aaaagttcgt ctgtgaagga tttgcgactg gcaaggaagc cttgaccggt gcagttgata
    19981 ttttggtcga agccttatcg gaagatgtga ccttgcgttc tatgacttat caggaagtgc
    20041 tgagacactc taaactcact tctcaagcca aggatgaaag tcttgatgaa aagcaggttt
    20101 ttcagattta ttatgatttt tcagagacag ttggaactat gcaaggctat cgtaccttgg
    20161 ctctcaatcg tggggagaaa cttggtgtct tgaagatcgg ttttgaacat gcgacggacc
    20221 gtattcttgc cttctttgct actcgtttca aggtgaaaaa tgcttatatt gatgaagttg
    20281 ttcagcaatc cgttaagaaa aaggtcttgc ctgctattga gcgtcgtatt cggacagaat
    20341 taactgagaa agctgaagag ggagctatcc aacttttttc tgacaatctg cgcaatctcc
    20401 tcttggttgc tccactgaaa gggcgcgtgg ttcttgggtt tgacccagcc tttcgtacag
    20461 gtgccaagct agctgtcgtg gatgcaacag gaaaaatgct gacaactcag gttatttatc
    20521 ctgttaaacc agcatcagct cgtcaaatcg aagaagccaa gaaagattta gcagatttaa
    20581 ttggtcaata cggtgtagag attattgcca ttggaaatgg aacggccagt cgtgaaagtg
    20641 aagcttttgt agcggaagtt ctgaaagatt tccctgaagt cagctatgtt atcgttaatg
    20701 aaagtggtgc ttctgtctat tctgccagcg aacttgctcg tcaggagttt ccagacttga
    20761 ccgttgaaaa acgctctgcc atttctatcg cccgtcgttt gcaagatcct cttgcggaat
    20821 tggtcaaaat cgatcctaag tcaattggtg tcggtcaata ccaacacgat gtcagtcaga
    20881 agaaactatc tgagagtctg gactttgttg tcgatacagt ggttaaccaa gttggtgtca
    20941 atgtcaatac agctagccca gctcttcttt cacacgtagc tggactcaat aaaaccattt
    21001 ctgaaaatat cgtcaaatac cgtgaggaag agggaaaaat cacttcacgc tcccaaatca
    21061 agaaagttcc tcgtttgggg gccaaggctt ttgaacaggc tgctggtttc ctccgtatcc
    21121 ctgaaagtag caatatcctt gataatacag gagttcaccc agaaaattac gctgccgtta
    21181 aggaactctt caaatgcttg gatattaagg atctgaatga agaggcccaa agcaaactca
    21241 agtcgctttc agtcaaggaa atggcgcaag agttagacct tggtccagaa actcttaaag
    21301 atatcattgc agatcttctc aaaccaggtc gagatttccg tgattccttt gatgctccag
    21361 ttctccgtca agatgtccta gatatcaagg acttagtggt tggacaaaag ctagaaggag
    21421 tggtgcgtaa cgttgttgat ttcggtgctt ttgttgatat cggaattcat gaggacggtc
    21481 tcatccatat ttcccatatg agtcgcaagt ttatcaaaca ccctagtcaa gtggtggcag
    21541 ttggagattt ggtgagcgtt tgggttaaga aaattgatac tgaacgtgaa aaagttaatc
    21601 tgtctctcct agctccaaat gaaactgact gattacgtca agcaggtttc actagaagac
    21661 ttcggcagac cttttatcca tcatgtccag tggaataggc gtctacgttc gacaggtggg
    21721 cgatttttcc ccaaagatgg gcatttggat tttaatccca aggtttatca ggaactgggg
    21781 ttggacgttt ttaggaaaat tgtccgacat gaactctgtc attatcacct ctattttcaa
    21841 gggaaaggct atcaacacaa ggatcgggat tttaaggaac tgttgaaagc agtggatgga
    21901 ttacggtttg taccatcctt gcccaatagt aactccaagc caatcaagct ctatcgttgc
    21961 caatcctgcc agcaaactta tcagcgtaag cgtaggattg ataccaaacg ctatcgctgt
    22021 ggactttgtc gaggaaagtt gctattagta aatcagcctg aggactgatg aaagccgagc
    22081 ctatccgtga tatactatgt ctaacctagc agaaagagga aatatcatga acagtaagtt
    22141 ttataaaatg agacgaaatc gcatgatttc aggagtttta gcaggtctgt cagacaagtg
    22201 gaactttgat gttacccttg tacgttttct gtttgccatt tttacagtcg caaactttgg
    22261 acttggggtg attatctata tcatcctagc ttctatcatg ccaaccaagg aagaaatcga
    22321 agcagaaatg tacggaacag gcccacgtaa acgcaaagaa gctcaagcca ttgacgataa
    22381 tgaaggctgg ttttggtgag gttttacaaa agatttggaa tacgcaaaaa gctttaaatc
    22441 aatagtctaa actgcttgat ttaaagcttt tttactttta tactcaataa aaaa
//
LOCUS       DBEJHE010000030        21848 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC4 isolate 671759
            SAMN38261586-rid24793303.denovo.30, whole genome shotgun sequence.
ACCESSION   DBEJHE010000030 DBEJHE010000000
VERSION     DBEJHE010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261586
            Sequence Read Archive: SRR26833752
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 21848)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21848)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576136.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576136.1
            Genome Coverage       :: 109x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 19:48:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,067
            CDSs (total)                      :: 2,029
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 131
            CDSs (without protein)            :: 131
            Pseudo Genes (ambiguous residues) :: 0 of 131
            Pseudo Genes (frameshifted)       :: 64 of 131
            Pseudo Genes (incomplete)         :: 59 of 131
            Pseudo Genes (internal stop)      :: 46 of 131
            Pseudo Genes (multiple problems)  :: 32 of 131
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21848
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261586-rid24793303.denovo.30"
                     /strain="GPSC4"
                     /isolate="671759"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            <1..311
                     /locus_tag="ACL3EZ_001599"
     CDS             <1..311
                     /locus_tag="ACL3EZ_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007895264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGR0393139.1"
                     /translation="ANSLEINVDCDYEPESAPQKGLYMNERYQCLKTKEYQALLSSKG
                     RQIFAKRKIDMKSVFGQIKVCLGYKRCHLRGKRQVRIDMGFILMANNLLKYNKRKRQN
                     "
     gene            complement(422..625)
                     /locus_tag="ACL3EZ_001600"
     CDS             complement(422..625)
                     /locus_tag="ACL3EZ_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HGR0393140.1"
                     /translation="MSVEEKLNQAKGSIKEGVGKAIGDEKMEKEGAAEKVVSKVKEVA
                     EDAKDAVEGAVEGVKNMLSGDDK"
     gene            complement(656..1264)
                     /locus_tag="ACL3EZ_001601"
     CDS             complement(656..1264)
                     /locus_tag="ACL3EZ_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HGR0393141.1"
                     /translation="MSNEKNTNTNVEKKDATVVAHEIKGELTYEDKVIQKIIGLSLEN
                     VSGLLGIDGGFFSNLKEKIVNSDDVTSGVNVEVGKTQVAVDLNVIVEYQKNVPALYSE
                     IREIVSSEVAKMTDLEIVEINVNVVDIKTKEQHEADSVSLQDRVSDVAESTGEFTSEQ
                     FEKAKSGLGSGFSTVQEKVSEGVEAVKGAANGVVSHENTRVN"
     gene            complement(1303..1473)
                     /locus_tag="ACL3EZ_001602"
     CDS             complement(1303..1473)
                     /locus_tag="ACL3EZ_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HGR0393142.1"
                     /translation="MEWLKQYRYPIIAGLIGVFLACLIVSFGFFKTIFVLILGALGVA
                     AGLYIEKNYIDK"
     gene            complement(1485..2051)
                     /gene="amaP"
                     /locus_tag="ACL3EZ_001603"
     CDS             complement(1485..2051)
                     /gene="amaP"
                     /locus_tag="ACL3EZ_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HGR0393143.1"
                     /translation="MSKAKKICFIIFCILILTIFLPVLIDYHQVSDLGIHLLSWRQNS
                     VVEFYLARYVFWGTVVLSTLVLLSILVVMFYPKRYLEIQLETKNDTLKLKNSAIEGFV
                     RSLVSDHRLIKNPTVHVNLRKNKCFVHVEGKILPSDNIADRCQIIQNEITNGLKQFFG
                     IERQVKLEVAVKNYQPKPQNKKTVSRVK"
     gene            complement(2135..2299)
                     /locus_tag="ACL3EZ_001604"
     CDS             complement(2135..2299)
                     /locus_tag="ACL3EZ_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HGR0393144.1"
                     /translation="MGIIANVFAGLVGAYAGQSLLGSWGPSIAEMALLPSIVGAAIVI
                     TVVSFFTGRK"
     gene            2742..4223
                     /gene="mgaSpn"
                     /locus_tag="ACL3EZ_001605"
                     /gene_synonym="mgrA"
     CDS             2742..4223
                     /gene="mgaSpn"
                     /locus_tag="ACL3EZ_001605"
                     /gene_synonym="mgrA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virulence factor transcriptional regulator
                     MgaSpn"
                     /protein_id="HGR0393145.1"
                     /translation="MRDLLSKKSHRQLELLELLFEHKRWFHRSELAELLNCTERAVKD
                     DLSHVKSAFPDLIFHSSTNGIRIINTDDSDIEMVYHHFFKHSTHFSILEFIFFNEGCQ
                     AESICKEFYISSSSLYRIISQINKVIKRQFQFEVSLTPVQIIGNERDIRYFFAQYFSE
                     KYYFLEWPFENFSSEPLSQLLELVYKETSFPMNLSTHRMLKLLLVTNLYRIKFGHFME
                     VDKDSFNDQSLDFLMQAEGIEGVAQSFESEYNISLDEEVVCQLFVSYFQKMFFIDESL
                     FMKCVKKDSYVEKSYHLLSDFIDQISVKYQIEMENKDNLIWHLHNTAHLYRQELFTEF
                     ILFDQKGNTIRNFQNIFPKFVSDIKKELSHYLETLEVCSSSMMVNHLSYTFITHTKHL
                     VINLLQNQPKLKVLVMSNFDQYHAKFVAETLSYYCSNNFELEVWTELELSKESLEDSP
                     YDIIISNFIIPPIENKRLIYSNNINTVSLIYLLNAMMFIRLDE"
     gene            4585..5586
                     /locus_tag="ACL3EZ_001606"
     CDS             4585..5586
                     /locus_tag="ACL3EZ_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGR0393146.1"
                     /translation="MVEQRKSITMKDVALEAGVSVGTVSRVINKEKGIKEVTLKKVEQ
                     AIKTLNYIPDYYARGMKKNRTETIAIIVPSIWHPFFSEFAMHVENEVYKRNNKLLLCS
                     INGTNREQDYLEMLRHNKVDGVVAITYSPIEHYLTSGIPFVSIDRTYSDIAIPCVSSD
                     NDAGGREAAKQLISKGCQHLAFVGGHNTTINETKRRRISFEKYVQEHKIPLSIFDLDE
                     TVTDYYGKLESFLEENSSIDGIFTINDFTALDVIEILEKNGKRIPHDVQIIGYDGIKM
                     AGDRDYLLSTIEQPLEEMAKEAVRILFDIIDGKTVNLQTILPVKFVEGKTTKNENKS"
     gene            5737..6654
                     /locus_tag="ACL3EZ_001607"
     CDS             5737..6654
                     /locus_tag="ACL3EZ_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001084977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0393147.1"
                     /translation="MNSKAKQVSLWERIKKQKLLLLMTVPGLVLTFIFKYIPMYGVLI
                     AFKDYNPLKGILGSDWIGFSEFTKFISSPNFGILLANTLKLSIYGLLLGFLPPIILAI
                     MLNQLLSEKVKKRIQLILYAPNFISVVVIVGMIFLFFSVGGPINNFLSMFGMKADFLT
                     NPDFFRPLYIFSGIWQGMGWASTLYTATLVNVDPALVEAARLDGANIFQRIWHIDIPA
                     LKPIMVIQFVLAAGGIMNVGYEKAFLMQTSLNLPTSEIISTYVYKVGLVSGDYSYSTA
                     VGLFNAVINVVLLVAVNQIVKRMNNGEGI"
     gene            6665..7555
                     /locus_tag="ACL3EZ_001608"
     CDS             6665..7555
                     /locus_tag="ACL3EZ_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGR0393148.1"
                     /translation="MKNSIMDTKFDRRILLLNKIIIVFIVLMTLLPLLYIVVASFMDP
                     KVLVSRGISFNPADWTVEGYQRVFSDQSILRGFINSLLYSFGFAALTVLLSVFTAYPL
                     SKKDLVGRRWINYFLIVTMFFGGGLVPTYLLVKELGMLNTPWAIIVPGAVNVWNIILA
                     RAYFQGLPEELVEAAVIDGANDLQIFFKIMLPLAKPIMFVLFLYAFVGQWNSYFDAMI
                     YIKDPNLEPLQLVLRKILIQSQPGQDMIGAQAAMNEMKRLAELIKYATIVISSLPLIV
                     MYPFFQKYFDKGIMAGSLKG"
     gene            7584..9200
                     /locus_tag="ACL3EZ_001609"
     CDS             7584..9200
                     /locus_tag="ACL3EZ_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGR0393149.1"
                     /translation="MKFKTFSKSAVLLTASLAVLAACGSKNTASSPDYKLEGVTFPLQ
                     EKKTLKFMTASSPLSPKDPNEKLILQRLEKETGVHIDWTNYQSDFAEKRNLDISSGDL
                     PDAIHNDGASDVDLMNWAKKGVIIPVEDLIDKYMPNLKKILDEKPEYKALMTAPDGHI
                     YSFPWIEELGDGKESIHSVNDMAWINKDWLKKLGLEMPKTTDDLIKVLEAFKNGDPNG
                     NGEADEIPFSFISGNGNEDFKFLFAAFGIGDNDDHLVVGNDGKVDFTADNDNYKEGVK
                     FIRQLQEKGLIDKEAFEHDWNSYIAKGHDQKFGVYFTWDKNNVTGSNESYDVLPVLAG
                     PSGQKHVARTNGMGFARDKMVITSVNKNLELTAKWIDAQYAPLQSVQNNWGTYGDDKQ
                     QNIFELDQASNSLKHLPLNGTAPAELRQKTEVGGPLAILDSYYGKVTTMPDDAKWRLD
                     LIKEYYVPYMSNDNNYPRVFMTQEDLDKIAHIEADMNDYIYRKRAEWIVNGNIDTEWD
                     DYKKELEKYGLSDYLAIKQKYYDQYQANKN"
     gene            9210..10529
                     /locus_tag="ACL3EZ_001610"
     CDS             9210..10529
                     /locus_tag="ACL3EZ_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HGR0393150.1"
                     /translation="MGDKKYTVEKANRFIAENKHLVNTQYKPEEHFSAEIGWINDPNG
                     FVYFRGEYHLFYQFYPYDSVWGPMHWGHAKSKDLVTWEHLPVALAPDQDYDRNGCFSG
                     SAIVKDDRLWLMYTGHIEEKNGVRQVQNMAFSDDGIHFEKIEQNPVATGADLPDELIA
                     ADFRDPKLFEKDGRYYSVVAAKHKDNVGCIVLLGSDNLVEWQFESIFLKGVEHQGFMW
                     ECPDYFELDGKDCLIMSPMRYQREGDSYHNINSSLLFTGKVEWGEKCFIPESVQEIDH
                     GQDFYAPQTLLDDQNRRILIAWMQTWGRTLPTHDQEHKWACAMTLPRILRLEDGKLRQ
                     FPVKKGQYQIQIDKDCHYHLGNDTDYLEFGYDSNAQQVYIDRSHLIQKILGEEEQDTS
                     RRYVDIEAKELEVVLDKNSIEIFVNQGEASLTATYYLTVPAELSRID"
     gene            complement(10739..10811)
                     /locus_tag="ACL3EZ_001611"
     tRNA            complement(10739..10811)
                     /locus_tag="ACL3EZ_001611"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10776..10778),aa:Lys,seq:ctt)
     gene            complement(11075..12346)
                     /locus_tag="ACL3EZ_001612"
     CDS             complement(11075..12346)
                     /locus_tag="ACL3EZ_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001113185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HGR0393151.1"
                     /translation="MPDNLALRMRPKTIDQVIGQEHLVGPGKIIRRMVEANRLSSMIL
                     YGPPGIGKTSIASAIAGTTKYAFRTFNATVDSKKRLQEISEEAKFSGGLVLLLDEIHR
                     LDKTKQDFLLPLLESGLVIMIGATTENPFFSVTPAIRSRVQIFELEPLSNQDVKEALQ
                     IALSNPERGFDFPIELDEDALDFIATSTNGDLRSAFNSLDLAVLSTPENDEGIRHITL
                     DIMENSLQRSYITMDKDGDGHYDVLSALQKSIRGSDVDASLHYAARLIEAGDLPSLAR
                     RLTVIAYEDIGLANPEAQIHTVTALDAAQRIGFPEARILIANVVIDLALSPKSNSAYV
                     AMDKALADLKASGHLPIPRHLRDGHYSGSKELGNAQDYLYPHNYPGNWVKQDYLPEKI
                     RNHHYFQAEDTGKYERALAQRKEAIDHLRKI"
     gene            12616..12854
                     /locus_tag="ACL3EZ_001613"
                     /pseudo
     CDS             12616..12854
                     /locus_tag="ACL3EZ_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818079.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            13019..13198
                     /locus_tag="ACL3EZ_001614"
     CDS             13019..13198
                     /locus_tag="ACL3EZ_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0393152.1"
                     /translation="MNLIFEEYQFVKIGDKKYRVRSGPMIHSTPPQSVLDRDTFTIDY
                     TDDELLDKEAVFTTH"
     gene            13335..13514
                     /locus_tag="ACL3EZ_001615"
     CDS             13335..13514
                     /locus_tag="ACL3EZ_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HGR0393153.1"
                     /translation="MPMTQKEMVKLLTAHGWIKTRGGKGSHIKIEKQGERPITILHGE
                     LNKYTERGIGKQAGL"
     gene            13551..14003
                     /locus_tag="ACL3EZ_001616"
     CDS             13551..14003
                     /locus_tag="ACL3EZ_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000961815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HGR0393154.1"
                     /translation="MLVTYPALFYYDDTDGTEATYFVHFPDFEYSATQGEGISEALAM
                     GSEWLGITVADLIESDGELPQPSDINSLSLIDNDPFKDDEDFVSTYDLDKSFISMVSV
                     DVSEYLGSQEPIKKTLTIPKWADKLGREMGLNFSQTLTDAIADKKVQA"
     gene            14294..14764
                     /locus_tag="ACL3EZ_001617"
     CDS             14294..14764
                     /locus_tag="ACL3EZ_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HGR0393155.1"
                     /translation="MATYGFLDILEEELDKNFPFDFEISWDKRNHAVEVSFLLEAQNA
                     AGVEMVDEDGEVSSDDILFEEAVLFYNPAKSTVNAEDYLTVIPYLPKKGFSREFLAYF
                     ALFLKDTAEVGLDTLMDFLEDPEAEEFVMEWNQEVFEEGKVGLEEGEFYPYPRY"
     gene            14783..15850
                     /locus_tag="ACL3EZ_001618"
     CDS             14783..15850
                     /locus_tag="ACL3EZ_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="site-2 protease family protein"
                     /protein_id="HGR0393156.1"
                     /translation="MKKIGTYLVYVLAVVFIMLAFACGTIAFAELGYSAVLAFTFGYA
                     FALLSMYLIFILHELGHAFCGYLTGYRLVAFGLGHFILTKKSGRFHLSRTAILKNVGA
                     QYIGLKEDESDQRIILMLSGGLMVHLGLILLAIVFGFLTRSWYFAGTWIFLNLSFFLN
                     NILPVDITDGAKIWELLQHPENTKYAYLVLRHSAQTLLAPQEYDLKDFVQAVPEDARG
                     SFADGVLGMQGEVSILEGKEEVAKQQFQALLERTTTPMMQTVAQLSLLHIALLEGDFE
                     QAEQYASIRQVKSFLSLKLSNLQVIQAWYQLKVKKDVDRTRKALKIARQKMDSSRMLR
                     DEKRYYENLLAELEKELAEGV"
     gene            15852..16280
                     /locus_tag="ACL3EZ_001619"
     CDS             15852..16280
                     /locus_tag="ACL3EZ_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HGR0393157.1"
                     /translation="MEIEISDFTGCKIALFCGDKLLTILRDDKASIPWANMWELPGGG
                     REGDESPFECVAREVYEELGIHLTEDCLLWSKIYPSMLFADKQSVFLVGQLTQNQFDS
                     IVFGDEGQGYQLMNVEEFLSSSQVVPQLQERLKDYLKVSD"
     gene            16418..17368
                     /gene="prmA"
                     /locus_tag="ACL3EZ_001620"
     CDS             16418..17368
                     /gene="prmA"
                     /locus_tag="ACL3EZ_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000451122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HGR0393158.1"
                     /translation="METWQELKVTVKREGEELVSNLLIELGAQGVAIEDSMDYVGNMD
                     RFGEIFPEVEQQEEIVVTAYYPDTVDVTVVEADLQARLAELTDFMDLGELKIGTTALA
                     EEDWADNWKKYYEPARITHDLTIVPSWTDYEATAGEMIIKLDPGMAFGTGTHPTTKMS
                     LFALEQVLRGGETVLDVGTGSGVLSIASSLLGAKEIFAYDLDDVAVRVAQENIELNPG
                     MENIHVAAGDLLKGVEIEADVIVANILADILIHLIDDAYRLVKDEGYLIMSGIIKDKW
                     DMVRESAESAGFFLETHMVQGEWNTCVFKKTKDISGVIGG"
     gene            17370..18113
                     /locus_tag="ACL3EZ_001621"
     CDS             17370..18113
                     /locus_tag="ACL3EZ_001621"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001188214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HGR0393159.1"
                     /translation="MQQYFVKGSAISPVTIEDKETSKHMFQVMRLKEEDEVTLVFDDG
                     IKRLARVLDMENRQFELVQELNDNVELPVQVTIASGFPKGDKLEFIAQKVTELGASQI
                     WAFPADWSVAKWDGKKLGKKVEKLEKIALGAAEQSKRNIVPSIKLFEKKADFLAQLDQ
                     FDSIIVAYEESAKEGEAAALLQAVTGLETGSKLLFIFGPEGGLSPAEIESFEAKGAVL
                     AGLGPRILRAETAPLYALSALSVLVELEK"
     gene            18124..19920
                     /gene="pepF"
                     /locus_tag="ACL3EZ_001622"
     CDS             18124..19920
                     /gene="pepF"
                     /locus_tag="ACL3EZ_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HGR0393160.1"
                     /translation="MEQKHRSEFPEKELWDLTALYQDREDFLRAIEKAREDINQFSRD
                     YKGNLHTFEDFEKAFAELEQIYIQMSHIGNYAFMPQTTDYSNDEFANIAQAGMEFETD
                     ASVALTFFDDALVVADEEVLDRLGELPHLTAAIRQAKIKKAHYLGADVEKALTNLGEV
                     FYSPQDIYTKMRAGDFEMADFEAHGKTYKNSFVTYENFYQNHEDAEVREKSFRSFSEG
                     LRKHQNTAAAAYLAQVKSEKLLADMKGYDSVFDYLLAEQEVDRVMFDRQIDLIMKDFA
                     PVAQRYLKHVAKVNGLEKMTFADWKLDLDSALNPEVTIDDAYDLVMKSVEPLGQEYCQ
                     EVARYQEERWVDFAANSGKDSGGYAADPYRVHPYVLMSWTGRLSDVYTLIHEIGHSGQ
                     FIFSDNHQSYFNAHMSTYYVEAPSTFNELLLSDYLENQSNDPRQKRFALAHRLTDTYF
                     HNFITHLLEAAFQRKVYTLIEEGETFGASKLNSIMKEVLTDFWGDAIEIDDDAALTWM
                     RQAHYYMGLYSYTYSAGLVISTAGYLHLKNSETGAEDWLNLLKSGGSKTPLESAMIIG
                     ADISTDKPLRDTIQFLSDTVDQIIAYSAELGE"
     gene            20167..20958
                     /locus_tag="ACL3EZ_001623"
     CDS             20167..20958
                     /locus_tag="ACL3EZ_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2785 domain-containing protein"
                     /protein_id="HGR0393161.1"
                     /translation="MYQDLLRKIAEEKPNYNQEEIQWLLDHLGDPSPEIRDDLVFTSF
                     AIGIQEELFTQEQFHFIAEGVSSDVGLDKEIDKVGLPTLERSFRALVYANLLYADANQ
                     QSVFYQGLQLEIRNVFSNQGLHYLSKEKDTTGFSSQYGWVHAFAHGADLLTEVVCHPD
                     FPINRIHEVFDILGQLFKRMSIRFTDDEDWRLARVIYEPILQGKLEQEQVASWIKTVD
                     FPIEEREDFSKFSNFRSCLVEVYVQLDQRNSLQDELKEAIQSFQY"
     gene            21069..21737
                     /locus_tag="ACL3EZ_001624"
     CDS             21069..21737
                     /locus_tag="ACL3EZ_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MIP/aquaporin family protein"
                     /protein_id="HGR0393162.1"
                     /translation="MKKFVAELIGTFMLVFVGTGAVVFGNGFDGLGHLGIAFAFGLAI
                     VVAAYSIGTVSGAHLNPAVSIAMFVNKRLSSSELVNYILGQVVGAFIASGAVFFLLAN
                     SGMSTASLGENALANGVTVFGGFLFEVIATFLFVLVIMTVTSESKGNGPIAGLVIGLS
                     LMAMILVGLKITGLSVNPARSLAPAVLVGGAALQQVWIFILAPIAGGVLAALVAKNFL
                     GTEE"
BASE COUNT         6735 a         3794 c         4565 g         6754 t
ORIGIN      
        1 aagcaaacag ccttgaaatc aatgttgact gcgattatga acctgaatca gcccctcaaa
       61 agggactgta tatgaatgaa cgttaccagt gtttaaaaac taaagaatat caggcacttt
      121 tatcttccaa gggtagacaa attttcgcta aacgtaagat tgatatgaaa tctgtctttg
      181 ggcagataaa ggtttgtttg ggttataaga gatgtcatct gagaggtaag cgtcaagtga
      241 gaattgacat gggattcata ctcatggcca acaacctgct gaaatataat aagagaaaga
      301 ggcaaaatta aaaagctaga gttccgcaat tgggaatctc tagctttttg ttttctgaga
      361 atcatcttga ctcagactct tttgactaat gttaccaaaa aagataaagt aacttttaac
      421 cttatttatc gtcgccactc aacatgtttt taacaccttc tacagcacct tctacagcgt
      481 ctttagcgtc ttcggcaact tcttttactt tagaaacaac tttttcagct gctccttctt
      541 tttccatttt ttcatcaccg atggctttcc caacaccttc tttaatagaa cctttagctt
      601 gatttaattt ttcttctact gacatgataa tttctcctgt tatatttatt ttatcttagt
      661 ttacacgagt gttttcgtga gatactacac catttgctgc acctttaaca gcttctacac
      721 cttcgctaac tttttcttga acagttgaga aaccagatcc aagaccagat ttagcttttt
      781 cgaattgttc tgaagtgaat tctcctgttg attcagcaac gtcagatacg cgatcttgaa
      841 ggcttactga gtctgcttca tgctgttctt tagttttgat gtcgacaacg tttacgttga
      901 tttcaacaat ttccaagtca gtcattttag caacttctga agatacgatt tctctgattt
      961 ctgaatataa agctggaaca tttttttggt actcaacaat aacgtttaag tcaactgcaa
     1021 cttgtgtttt accaacttct acgttaacac cacttgttac gtcatcgctg ttaacgattt
     1081 tttctttaag atttgagaag aaaccaccat cgattcccaa aagacctgaa acgttttcta
     1141 gtgaaagacc aatgattttt tggataactt tatcttcgta agtaagttcc cctttgattt
     1201 cgtgagctac aacagtagca tctttctttt ctacgttagt gtttgtgttt ttttcgtttg
     1261 acatatgaaa ctcctttaat taaattagta atttttattt ttttatttat ctatatagtt
     1321 tttttcgata tataatccag ctgcaactcc cagtgctcct aaaatcaata caaatattgt
     1381 tttgaagaag ccaaaggaga caatcaaaca agccagaaat acgcctatga gaccagcgat
     1441 aattggatat cgatattgtt taagccattc cattttttac ttccttactt cacacgacta
     1501 acagtctttt tgttttgagg ttttggttgg taatttttta ctgcaacttc aagttttact
     1561 tgacgctcaa taccaaaaaa ctgcttcaat ccattagtta tttcattttg aattatttgg
     1621 catctgtcag cgatgttgtc tgaaggaaga attttacctt ctacatgaac gaaacattta
     1681 ttttttcgta aatttacatg aacagttggg ttcttgatca atctatgatc actcaccaaa
     1741 cttctaacaa aaccttcgat tgccgaattc tttaatttta atgtatcgtt tttagtttca
     1801 agttggattt ccaagtaacg tttaggataa aacatcacaa ctaaaatgga taataaaact
     1861 aaagttgata gaaccactgt cccccaaaag acatatctag caagatagaa ttcaactacg
     1921 gagttctgtc tccagctaag tagatgaata cctagatcac taacttgatg ataatctatc
     1981 aaaacaggaa ggaaaattgt caagattaaa atacagaaaa taatgaaaca tattttcttt
     2041 gcttttgaca tatacaatcc tttcgattta acatttaaac tatttttccc gtcattgatt
     2101 taaaaatagt ttgctaactt tactggcgaa aagtttactt tctacctgta aagaatgaca
     2161 ctacagtaat cacaatcgct gcacctacaa tagatgggag caaagccatt tcagcgattg
     2221 atggacccca actacctaaa agagattgtc ctgcatatgc cccgactaaa ccagcgaata
     2281 catttgcgat gattcccata gaactacttt tttagtgatt ttacctgcca agagaccaat
     2341 aagacctcca gcaataattg atcacaacac tgcctaccct ccttttttat tttaatatca
     2401 aaaaatcaat ttctttgatt aatactatta tataacttta atatagaaaa gtcaattatt
     2461 tcgattgtta ttattatata attttaaaaa atcaaattct ttaattgttg ctattatata
     2521 atttttaaaa ttaaaaatat aatctttaga cttgaatttg attctgtatt cacgccctca
     2581 atagacggta aaataagaaa attgtttata tattgtctcc gtagtgttat tatacgaaat
     2641 aaaagatttt aggaaaagtc gttatatcat gctataccta ttctttgtgg tataattgca
     2701 agaggtttaa tccgataatt tataaagaga gaaagatatt catgagagat ttattatcta
     2761 aaaaaagtca taggcaatta gaattattag aattattatt tgaacataaa cgttggtttc
     2821 atcgttctga actagcagag ttattaaatt gtacagaacg tgcagtcaaa gatgatctat
     2881 cccatgttaa atctgctttt cctgacttga tttttcattc ttctactaat ggtatacgca
     2941 ttattaatac cgatgatagt gatattgaaa tggtttacca tcatttcttt aaacattcaa
     3001 ctcatttttc gattttagaa ttcatcttct ttaatgaagg ttgtcaagct gagagtattt
     3061 gtaaagaatt ttatatcagt tcatcttcgc tctatcgtat tattagccaa atcaataaag
     3121 tgattaaaag gcaatttcaa tttgaagtca gtctgacccc tgttcaaatc attggaaatg
     3181 agagagacat tcgttacttt tttgcacaat atttttcaga aaaatattat ttcctagaat
     3241 ggccatttga aaatttttca tcagagccac tatctcaatt gttagaattg gtttataagg
     3301 aaacaagctt tccaatgaat ttgtcaacgc atagaatgct aaagttgctc ctagttacga
     3361 acctatatag aataaagttt ggtcatttta tggaagtaga taaagattct tttaacgacc
     3421 aaagtttgga ttttttaatg caggcagaag gaatagaagg tgttgctcag agttttgaat
     3481 cagaatacaa tatctcttta gatgaagaag ttgtttgcca attatttgtg tcttactttc
     3541 aaaaaatgtt tttcatagat gaaagtctct ttatgaaatg cgtaaaaaag gatagttatg
     3601 ttgaaaaatc ttaccatcta ttgagtgatt ttattgatca gatttcagtc aagtatcaga
     3661 ttgaaatgga gaataaggat aatctgattt ggcatctgca taataccgca catctgtatc
     3721 gtcaagagtt gtttactgag tttattttat ttgatcaaaa agggaataca atcaggaact
     3781 ttcaaaatat ttttccaaaa tttgtttcag atataaaaaa agagctttct cactatttag
     3841 agactcttga ggtttgttct agttcaatga tggtaaatca tctatcttat accttcatca
     3901 ctcataccaa acatttggtg attaatttgc tacaaaatca gcctaaacta aaggttttag
     3961 ttatgagtaa ttttgatcag tatcatgcaa aattcgttgc agagacactt tcttattact
     4021 gtagcaataa ttttgaactg gaagtttgga ctgaattaga attatcaaag gaatctttag
     4081 aagattcacc ttatgatatc attatttcta attttattat tcctcctatt gaaaataaga
     4141 gactcatcta ttcaaataat ataaacacgg tctcactcat atacttgtta aatgccatga
     4201 tgtttattcg attagatgag taaccaaaaa taacaaaaaa acgctatttc gcgtttgaac
     4261 tgtacctcaa aagttagaca gaaaaaatct aatttttggg gtgtttttgt taagaaaaga
     4321 ccttcaatca tttaagcaaa atgtacatct agatttatag ccctctaaaa ctcttgcttt
     4381 ttttgtagaa gatacgaaaa aagccataaa accaaggctt ttcctgtttt atgtagatgt
     4441 ttacacatga aaattgaagt attttcaaaa gctaattgga gtgattttat tcatgatggg
     4501 ataaatgatc tggccaaaaa tgattgagaa atagttgctt aaaaagcatt tgcatgatac
     4561 tatatattga aaggaggtga taatatggta gaacaaagaa aatcaattac catgaaagat
     4621 gttgctttag aagcaggagt tagtgttgga actgtttcac gtgtaattaa taaagaaaaa
     4681 ggcattaaag aagtaacttt gaaaaaagtg gaacaagcga ttaaaacttt gaattacatt
     4741 ccagattact atgctagagg aatgaaaaaa aatcgaacag aaacgattgc aatcattgta
     4801 ccaagtatct ggcatccctt cttttcagaa tttgctatgc atgtggaaaa tgaagtctat
     4861 aagagaaata acaaattact cttatgttct ataaatggta caaatagaga gcaagactat
     4921 ctggagatgt tgcgtcataa taaagttgat ggagtggttg ccattaccta tagtccaatt
     4981 gaacattact tgacgtcagg aattcccttt gttagtattg accgcacata ctcagatatt
     5041 gccattcctt gtgtttcatc agataatgat gcaggtggaa gagaagcagc taaacaatta
     5101 attagtaaag gatgtcagca tttagccttt gtgggcggac ataatacaac cattaatgaa
     5161 accaaacgtc gtagaatttc atttgaaaag tatgtccaag agcataaaat acctcttagt
     5221 atttttgatt tggatgagac agttactgac tattatggaa agctagagag tttcttggaa
     5281 gaaaattctt ctatagatgg aatttttaca atcaacgatt ttacagcttt ggatgtgatt
     5341 gaaatactag aaaaaaatgg caaacgtatt cctcatgatg tccaaattat tggatacgat
     5401 ggaattaaaa tggctggaga tagagattat ctactttcaa ctattgaaca accattggaa
     5461 gaaatggcaa aagaagcggt tcgtattttg tttgatataa ttgatggaaa gactgttaat
     5521 ttgcagacaa tcctaccagt aaaatttgtt gaaggaaaaa caacaaaaaa tgaaaataag
     5581 tcttgacaga aagcgctatc aatgatagaa tgaattcaga taaaaagatt tatttttaaa
     5641 acaaaaatga aacgtttcaa aaaaagaaat aaaaagacag cgccaagcgc tatcttttat
     5701 agaaaaaatg aaacgtttca aaaaaaggag gttgctatga atagcaaagc gaagcaagtt
     5761 tctctttggg aaagaatcaa gaaacaaaaa ctcttgttat tgatgactgt ccccggttta
     5821 gttttaacct ttatctttaa atacatccct atgtatgggg ttttaatcgc atttaaagat
     5881 tacaatcctt taaaaggaat tttagggagt gattggattg gtttttctga gtttacaaaa
     5941 ttcatatcct ctcccaactt tggtatcttg ttagccaaca cattaaaatt aagtatctat
     6001 ggtttattgc ttggcttttt accaccaatc attcttgcga ttatgctcaa tcaactcttg
     6061 agtgaaaaag tcaaaaaacg aattcagctc attttatacg caccaaactt tatctcagtc
     6121 gttgttattg tcggtatgat tttcctcttc ttttcagtgg gaggaccaat caacaatttt
     6181 ctttctatgt ttggaatgaa ggctgacttc ttgacaaatc cagacttctt tagaccctta
     6241 tacatcttta gtggtatctg gcaaggaatg ggctgggctt caacgctcta cacggcaaca
     6301 ttggtaaatg tagatccagc cttagtagaa gcagctcgac tggatggagc caatatcttc
     6361 caacgaatct ggcacattga tattccagct cttaagccta ttatggttat ccaatttgtt
     6421 ttagctgcag gtggaattat gaatgtcgga tatgaaaaag cattcttgat gcagacatcg
     6481 ttaaatttgc caacttctga aattatctcg acatatgtct ataaagttgg tcttgtatca
     6541 ggagactatt cttactcaac agcggttggt ttgtttaatg cagtgattaa cgtagtattg
     6601 cttgttgcag ttaaccaaat cgttaaacgc atgaataatg gtgaaggaat ttaaggagga
     6661 aagtatgaaa aattcgatta tggatacaaa atttgataga cgtatcttac tcttaaataa
     6721 aatcattatt gtctttatcg ttttgatgac tttgcttcct ttactttata tcgtcgtagc
     6781 atcctttatg gatcctaagg ttctggttag tagagggatt agctttaatc cagccgattg
     6841 gactgtagaa ggttaccagc gtgtattcag tgaccaatct attctaagag gttttatcaa
     6901 ttctctacta tactcttttg gatttgcagc tttaacagtc ttgctatctg tgtttacagc
     6961 ttatcctctt tctaagaaag acttggttgg acgtcgttgg attaactact tcttgattgt
     7021 aactatgttc tttggtggtg gtttagtccc aacttacttg ctcgtaaaag aattgggaat
     7081 gctcaatact ccatgggcta tcattgttcc aggtgctgtc aatgtttgga atattattct
     7141 tgctagggcc tatttccaag gattgcctga agaattagtt gaagctgctg tcattgatgg
     7201 tgcaaatgat ttacagattt tcttcaaaat catgcttcct cttgcaaaac caattatgtt
     7261 tgttctcttc ctttatgctt ttgtaggaca gtggaactca tactttgatg caatgattta
     7321 tatcaaggat ccaaacttgg aaccattgca acttgtactt cgtaaaattc tcattcagag
     7381 ccaaccaggt caagacatga ttggagcaca agcggctatg aatgaaatga aacgtttagc
     7441 tgaattgatt aaatacgcaa ctattgtcat ttccagcttg ccattgattg ttatgtatcc
     7501 attcttccaa aaatactttg ataaaggaat tatggctggt tcacttaaag gataaaaaaa
     7561 gaaaaaataa aaggagtttt ctcatgaaat tcaaaacatt ctcaaaatca gcagttttgt
     7621 tgacagctag tttagcagta cttgcagcct gtggctcaaa aaatacagct tcaagtccag
     7681 attataagtt ggaaggtgta acattcccgc ttcaagaaaa gaaaacattg aagtttatga
     7741 cagccagttc accgttatct cctaaagacc caaatgaaaa gttaattttg caacgtttgg
     7801 agaaggaaac tggcgttcat attgactgga ccaactacca atccgacttt gcagaaaaac
     7861 gtaacttgga tatttctagt ggtgatttac cagatgctat ccacaacgac ggagcttcag
     7921 atgtggactt gatgaactgg gctaaaaaag gtgttattat tccagttgaa gatttgattg
     7981 ataaatacat gccaaatctt aagaaaattt tggatgagaa accagagtac aaggccttga
     8041 tgacagcacc tgatgggcac atttactcat tcccatggat tgaagagctt ggagatggta
     8101 aagagtctat tcacagcgtc aacgatatgg cttggattaa caaagattgg cttaagaaac
     8161 ttggtcttga aatgccaaaa actactgatg atttgattaa agtcctagaa gctttcaaaa
     8221 acggggatcc aaatggaaat ggagaggctg atgaaattcc attttcattt attagtggta
     8281 acggaaacga agattttaaa ttcctatttg ctgcatttgg tataggggat aacgatgatc
     8341 atttagtagt aggaaatgat ggcaaagttg atttcacagc agataacgat aactataaag
     8401 aaggtgtcaa atttatccgt caattgcaag aaaaaggctt gattgataaa gaagctttcg
     8461 aacatgattg gaatagttac attgctaaag gtcatgatca gaaatttggt gtttacttta
     8521 catgggataa gaataatgtt actggaagta acgaaagtta tgatgtttta ccagtacttg
     8581 ctggaccaag tggtcaaaaa cacgtagctc gtacaaacgg tatgggattt gcacgtgaca
     8641 agatggttat taccagtgta aacaaaaacc tagaattgac agctaaatgg attgatgcac
     8701 aatacgctcc actccaatct gtgcaaaata actggggaac ttacggagat gacaaacaac
     8761 aaaacatctt tgaattggat caagcgtcaa atagtctaaa acacttacca ctaaacggaa
     8821 ctgcaccagc agaacttcgt caaaagactg aagtaggagg accactagct atcctagatt
     8881 catactatgg taaagtaaca accatgcctg atgatgccaa atggcgtttg gatcttatca
     8941 aagaatatta tgttccttac atgagcaatg acaataacta tccaagagtc tttatgacac
     9001 aggaagattt ggacaagatt gcccatatcg aagcagatat gaatgactat atctaccgta
     9061 aacgtgctga atggattgta aatggcaata ttgatactga gtgggatgat tacaagaaag
     9121 aacttgaaaa atacggactt tctgattacc tcgctattaa acaaaaatac tacgaccaat
     9181 accaagcaaa caaaaactag aggttgatta tgggagataa gaaatacaca gtagaaaaag
     9241 ccaatcgttt tatagcagaa aataaacatc tcgttaatac tcaatataag cctgaagaac
     9301 atttttcagc tgagattggt tggatcaatg atccaaatgg atttgtttat tttcgtggag
     9361 aataccatct cttttatcaa ttctatccat atgatagtgt ttggggacct atgcactggg
     9421 gacatgctaa aagtaaggac ttggtgactt gggagcactt gccagtggca cttgctcctg
     9481 atcaagatta tgaccgaaat ggttgtttct caggctctgc cattgtcaag gatgatcgcc
     9541 tctggctcat gtacactggg catatcgaag aaaaaaacgg tgtccgccaa gtgcaaaata
     9601 tggcattttc agacgacggg attcactttg aaaagattga acaaaatcca gttgcaacag
     9661 gagcagactt gccagatgag ttgattgctg ctgatttccg tgatccaaaa ctctttgaaa
     9721 aagatggacg ctattactcc gtagtagctg ccaaacacaa ggataatgtg ggctgtatcg
     9781 ttctactagg gtccgataac ctagtagaat ggcagttcga atccatcttt ttaaaagggg
     9841 tagaacacca agggtttatg tgggaatgcc cagattactt cgagttagat gggaaagatt
     9901 gccttattat gtcacccatg cgttatcagc gtgagggaga ctcatatcat aacatcaact
     9961 catcgctttt gttcacgggt aaggtagagt ggggagaaaa atgttttatc ccagaatcag
    10021 ttcaagaaat tgatcatggc caagacttct atgcgcctca aacattgttg gacgatcaaa
    10081 atcgtcgtat cctgattgct tggatgcaga catgggggcg tacccttcca acccatgacc
    10141 aagaacacaa gtgggcatgt gccatgactt tacctagaat tctaagattg gaagatggca
    10201 aactaagaca attccctgtt aaaaaaggcc aatatcaaat ccaaatagat aaagattgtc
    10261 attaccactt aggaaatgat acagattatc ttgaatttgg ttatgacagt aatgcgcagc
    10321 aagtttacat tgatcgtagc catcttattc aaaaaattct aggtgaagaa gaacaggaca
    10381 ctagtcgacg gtatgtagat attgaagcta aagaattgga agttgttcta gataaaaatt
    10441 ccatcgagat ttttgtcaat caaggtgaag caagcttgac tgcaacttat tacttaacgg
    10501 tgccagctga gctatcacga attgattaaa aattaagtta tttctcctaa agaaaaagtt
    10561 ctctttctaa aatagtggaa agaggacttt ttgtgttttg ggtatataag cttagtttat
    10621 ggtatttgta aaattggtgt tggattatga tttaaactag ttttctaaag aatttgaaaa
    10681 aaattttatt taagcaaaaa aagccctata ttataaggct ttttcctgtt gatttagatg
    10741 ccccctgcag ggctcgaacc tgcgacccat agattaagag tctactgctc taccaactga
    10801 gctaagaagg caaataaaaa gctgtattgg tgccgaaact tcacggtttg tattgaaccc
    10861 gcgcaattaa gcaggtgggc aactcgctct aactgaagct gtttccgtgt gagacggcct
    10921 acatgctgtt agaagacttt tgtttcccta ataatacaaa aaatagtcgg tcaacactta
    10981 agtgtgaagt cgtacaccac agcgtttcta tatttatatg ataccacttt ttcaaaaaaa
    11041 atcaagagga aagtgcagtt ttttgaaaag gatttcagat ttttcgcaaa tggtcgatag
    11101 cttcctttct ttgagccaaa gcccgttcat atttaccagt atcttctgct tggaaatagt
    11161 gatgattacg aattttttct ggcagatagt cttgcttgac ccaatttcca ggatagttgt
    11221 gtggatagag atagtcttgg gcattcccca gttccttgct tccactgtag tgcccatcac
    11281 gcaggtgtcg cggaataggc aagtgccctg atgctttgag gtcagcaagt gccttatcca
    11341 tagctacata ggctgagttg gattttggag aaagggccaa atcaatcacg acattggcga
    11401 tgagaatgcg ggcttctggg aaaccaatcc tttgtgcagc atccagagca gtcacggtat
    11461 gaatctgggc ctcaggattg gctaaaccga tatcttcata ggcgataaca gtcaagcgac
    11521 gagcgagact aggcagatcc ccagcctcaa tcaagcgggc agcatagtgg agactggcat
    11581 ccacatctga gccacggata gacttttgca gggcagatag aacatcatag tgaccgtctc
    11641 catccttgtc catagtgatg tagcttctct gaagactatt ttccatgatg tctaaggtga
    11701 tgtggcgaat gccctcgtca ttctcagggg tagagagaac agccaagtcc agtgagttaa
    11761 aggcagagcg aaggtctccg tttgtagagg ttgcgatgaa atccagcgca tcctcatcta
    11821 gttctattgg aaaatcaaaa ccacgttcag ggttacttag agctatctgc agggcctctt
    11881 tgacgtcttg gttagacaga ggttccaact caaaaatttg aacacggcta cgaatggcag
    11941 gagtgacgga aaagaaagga ttttcagtcg ttgctccaat catgatgacc agtccacttt
    12001 ccaagagagg caagaggaag tcttgcttgg tcttatctag tcgatgaatt tcgtctagca
    12061 ataggacgag accaccagaa aatttagctt cttccgagat ttcttgcagt ctctttttac
    12121 tatcaactgt cgcattgaaa gttcgaaagg catacttggt cgttccagcg atggcagagg
    12181 caatactggt tttgccgatt cccggagggc catatagaat catggaggac aggcggttgg
    12241 cttccaccat gcggcggatg atttttccag gtccgaccag atgctcctga ccgatgacct
    12301 ggtcgatggt tttagggcgc atgcgaagcg cgagattgtc tggcatagca gtcctttcta
    12361 gcgtggattt gagtagaatg actcatctac tatatcttac tatgtccatt ctagcctatt
    12421 agttgtgata tttcaatggt tttgtaataa tcagggagtg agatagaatc ttttttacta
    12481 tttaatttaa tgaggagagg tatcagcatg agagatttga ttttccttaa agctcaaaat
    12541 aggatagttg agcctaaaga agtggaagtg ctgacttgag aaataatatt gctgaatgtc
    12601 attgtatgaa ctataatgaa aagagaggtg ataagcaatg gaaatgatgg accaagtcag
    12661 gaaattttga tttttacaaa acaaattcgt cattggattc ttagtgatca agttatttca
    12721 gggaaaagaa aacttttctt ccggaagata ctccaaaaga gattttagat ttgtacgaaa
    12781 acattaaatc taaacttgat tttgcttacc aagaagttca ttctaataat gggttgaaaa
    12841 aatatgaaaa atagaataat tgatgttttt gaagtagtaa atcgcctcct tgtaataact
    12901 gttgaaaatc ctgatttcga agacttgaga gttaatcata ctcaatgaaa atcaaagagc
    12961 aaactaggaa actagccgca ggctgtactt gagtacggta aggcgacgtt gacgtggttt
    13021 gaatttgatt ttcgaagagt atcagtttgt aaaaattgga gataaaaaat atagagtacg
    13081 cagtggtcct atgattcatt caactccgcc tcaatctgtc ttagatcgag atacttttac
    13141 aattgactat acagatgatg aattgctcga taaagaagca gtttttacta ctcattagaa
    13201 aaataggtat gaataaattg gtttccctta gaaccacatc taggggcttt tatgtataat
    13261 agaataataa gtatcactcc tttacaatac gtgtaacacg tgttataatg gtgttgtcag
    13321 gaggtaaaag cgctatacct atgacacaaa aagagatggt taaactcctt acggcccatg
    13381 gttggataaa gactagaggc ggtaaaggct cccatattaa aatcgagaag caaggggaaa
    13441 gacctatcac aatccttcat ggtgagctga ataagtacac tgaaagaggg ataggaaagc
    13501 aagctgggtt gtaaaattca gtccctgctt tttgatatgg aggtagtgaa atgttagtta
    13561 cgtatccagc tttattttat tatgacgaca cagacggaac agaagcgact tattttgtcc
    13621 atttcccaga ttttgaatac tcagctacac aaggagaggg gatttctgag gctttggcta
    13681 tggggtcgga gtggctaggg ataactgttg cagatttgat agagagtgat ggagagttac
    13741 ctcagccatc agatatcaat agcttgtctt taattgataa tgatcctttt aaagatgatg
    13801 aagatttcgt gtcaacctat gaccttgata aatcttttat ttctatggta tctgttgatg
    13861 tatcagaata cctaggaagt caggaaccca ttaaaaagac tttgaccata ccaaaatggg
    13921 cagataagtt gggacgagaa atgggactta acttttctca gactttgaca gacgctattg
    13981 cagataagaa agttcaagcc taagattaag cgtggtatcg tggtaatagt caataaaaaa
    14041 gcacgtccac ttgtgctagt tactcgccta ttgattttat agatttatta gccctttcga
    14101 gggcttttta tattgatttt tatgagaaat gaagaaatca gacttttaag aaaatcactg
    14161 ataccaaggg tttaaatgag gtaatatggt ataattagga cataaaataa ttttgtggta
    14221 agatggtagt atctatttta gcatatttcc gagcaatcgg ggcgattaaa gagtcgcata
    14281 gaaagaggac aaaatggcaa catacggatt tttagatatt ttagaggaag agttggacaa
    14341 gaactttccc tttgactttg agattagttg ggacaagcgt aaccacgcgg tagaagtgag
    14401 ttttctattg gaagcgcaaa atgctgcagg tgtggagatg gtggatgaag acggagaggt
    14461 ttcatcagat gacattcttt ttgaggaagc ggtccttttc tacaatcctg ccaagtcaac
    14521 cgtcaatgca gaagactatt taacggttat cccttatcta cctaaaaaag gattttctcg
    14581 cgagttttta gcttattttg cccttttcct caaagatact gcggaggttg ggctagatac
    14641 cctcatggac tttttggaag atccagaagc agaggaattt gttatggaat ggaatcaaga
    14701 agtctttgaa gaaggaaaag ttggcttgga agagggagaa ttttatcctt atccaagata
    14761 ctaggagttg gttggaggtg ttatgaagaa aattgggact tatttggttt atgtgctagc
    14821 tgttgtcttt attatgctag cttttgcttg tggaacaatc gcatttgcag agttggggta
    14881 ttccgcagtt ttagccttta cttttggtta tgccttcgct cttctaagca tgtatttaat
    14941 ctttattctt catgagctgg gtcatgcttt ttgtggctac ttgacaggct atcggctggt
    15001 ggcttttgga ttaggacatt ttattttgac caaaaagtca ggcaggtttc atcttagtag
    15061 aacagccatt ctgaaaaatg ttggtgctca atacattggt ttaaaagagg atgaaagcga
    15121 tcaaagaatc atcctgatgc tttcaggagg cttgatggtt catctcggct tgatattatt
    15181 ggcgatagtg tttggatttt tgacaagaag ctggtatttt gcagggactt ggatttttct
    15241 taatttatct ttcttcctaa ataacatttt gccagtcgac atcaccgatg gagcaaaaat
    15301 ttgggaatta ctacaacacc ctgaaaatac caaatacgcc tacctggtat tgagacattc
    15361 tgctcaaact ttgctggctc ctcaagaata tgatttgaaa gactttgttc aagcagttcc
    15421 tgaggatgca cgagggagtt ttgcggatgg tgtattaggt atgcaaggtg aagtttccat
    15481 tttggaaggg aaggaagaag tagctaaaca gcagtttcaa gcattacttg agaggacaac
    15541 tactccgatg atgcagacag ttgcccaact atccctgctt catatcgcct tgttggaagg
    15601 agattttgag caagcggagc aatatgccag tattcgacag gtcaaatcgt ttctgtctct
    15661 caaactgtcc aatcttcaag tgatacaagc ctggtatcaa ttaaaggtga agaaagatgt
    15721 agatcgaact cgtaaggctc tcaagattgc tagacagaaa atggatagta gtcgaatgtt
    15781 gagggacgag aaacgctatt atgaaaactt gttagcagag ctggaaaagg aattagccga
    15841 aggagtctaa tatggaaata gagatttctg atttcacagg ttgcaagatt gctttgtttt
    15901 gtggggataa gcttttgact atcttacgcg atgataaggc aagcattccc tgggccaata
    15961 tgtgggaact gccaggtggt ggacgtgaag gtgatgaaag tccttttgag tgtgtagcgc
    16021 gtgaagttta tgaagaactg ggcattcatc tgactgaaga ttgtctgctt tggagtaaga
    16081 tttacccaag tatgcttttt gcagacaaac agtccgtttt tctagttggt cagttgacac
    16141 agaaccagtt tgacagtatc gtatttggag atgaaggaca gggctatcag ctgatgaatg
    16201 ttgaggaatt tcttagttcc agtcaagttg tgcctcagtt gcaagagaga ttaaaagatt
    16261 atttaaaagt aagtgattag aaaggatggt tcggttaaat ttctaaactg aacccgccct
    16321 aaacacggtg ccaaaaagat aaacttctct tagacacaaa cgtcttcaga gaatttccta
    16381 ttttggtttt gtgttttacg ggcttggtat cttaataatg gaaacatggc aagagttaaa
    16441 agttacagtg aagcgtgagg gagaggagtt ggtttccaat ctcttgattg agctaggagc
    16501 gcaaggtgtt gcgattgaag acagcatgga ctatgtggga aatatggacc gctttggcga
    16561 gattttccca gaggtggagc agcaagaaga aatcgtagtg acagcctact accctgacac
    16621 ggtggatgtg acagtggttg aggcggactt gcaggctcgc ttagcagaat tgacggattt
    16681 tatggatttg ggagagttaa aaataggtac gactgccttg gctgaggaag actgggcaga
    16741 caactggaag aaatactatg agccagctcg tatcactcat gatttgacca tcgttccctc
    16801 ttggacagac tatgaggcga ctgcggggga aatgattatc aagctggatc ctggcatggc
    16861 ttttggtact ggaacccacc caactaccaa gatgagcctt tttgccttgg aacaggttct
    16921 tcgtggtggc gaaacggtgc tagatgtggg gactggttca ggggttctct ctattgccag
    16981 ctcgcttctg ggggctaaag aaattttcgc ctatgacctg gatgatgtgg cggttcgtgt
    17041 ggctcaggaa aatattgagc tcaaccctgg catggaaaat atccatgtag cggctggaga
    17101 tttgcttaag ggtgtggaaa ttgaggcaga tgtgattgtg gctaatatct tggcggatat
    17161 cctcattcat ctaatagacg atgcctatcg tttggttaag gacgaaggct acctgatcat
    17221 gagtggcatt atcaaggata agtgggacat ggtgcgcgag tcggctgaat cagctggatt
    17281 tttcctcgaa actcacatgg ttcaagggga atggaatacc tgtgtcttta agaaaaccaa
    17341 ggatatctct ggtgtgattg gaggctagca tgcagcagta ttttgtaaaa ggcagtgcta
    17401 tctctcctgt cactatcgag gacaaggaaa ccagtaagca tatgtttcag gttatgcgct
    17461 tgaaagaaga ggatgaggtt accttagtct ttgatgatgg catcaagcgc ttggcgcgcg
    17521 tgctggatat ggaaaatcgt cagtttgagt tggtccaaga attaaatgac aatgtggaac
    17581 taccagtcca agtgaccatc gcatctggat ttcccaaggg agacaagctg gagttcatcg
    17641 ctcaaaaagt aaccgaactg ggtgctagcc aaatctgggc ctttcctgca gactggtcag
    17701 ttgccaagtg ggatggcaag aaattgggta aaaaagttga aaaactagaa aaaattgccc
    17761 ttggagcagc cgagcaaagc aagcgtaata ttgtaccaag tattaaactt ttcgagaaaa
    17821 aagcagattt tctagctcag ctggaccagt ttgactctat catagtagcc tatgaagaat
    17881 cagctaaaga aggagaagcc gctgcgcttc tgcaagcagt cactggtctt gaaacaggat
    17941 ccaaactgct ctttatcttt ggtccagaag gtggtctgtc acctgcagaa atcgaaagtt
    18001 ttgaagctaa aggagccgtt ttggcaggcc taggtcctcg tattttgcga gcagaaacag
    18061 caccgcttta cgccttatca gcccttagtg ttttagtaga attagagaaa taagaggaag
    18121 aaaatggaac aaaaacaccg ttcagaattt ccagagaagg aactctggga cttaacagcc
    18181 ctataccaag accgtgagga tttcttgcgt gcaatcgaga aagctcgtga agacatcaac
    18241 caatttagcc gtgactacaa gggtaatctt catacttttg aggatttcga gaaggccttt
    18301 gcggaattgg aacagatcta cattcagatg agccatattg gcaactatgc ttttatgcct
    18361 cagacgacgg actatagcaa tgacgaattt gccaatattg cccaagctgg gatggaattt
    18421 gaaacagatg ccagcgtagc cttgaccttc tttgacgatg ccttggtggt agcagacgag
    18481 gaagtcttgg accgtttggg tgaattgcct cacttgacgg cagctattcg tcaggccaaa
    18541 atcaaaaaag cccactatct aggggctgat gtggagaagg ccttgaccaa tctcggtgaa
    18601 gttttctata gtccgcagga catttatact aagatgcgag ctggggattt tgaaatggct
    18661 gactttgaag cccatggcaa gacctataaa aacagctttg tcacctatga gaatttctac
    18721 caaaatcacg aggatgctga ggttcgtgag aaatccttcc gttccttctc agagggactt
    18781 cgtaagcacc aaaatacggc tgcagcagcc tatctggctc aggtcaagtc tgaaaaactc
    18841 ttggctgata tgaagggata cgactctgtc tttgactatc ttctagctga acaagaagtg
    18901 gaccgtgtca tgtttgaccg ccagattgac ctcatcatga aggactttgc accagtcgct
    18961 cagagatacc tcaagcatgt tgccaaggta aatggtcttg aaaagatgac ctttgcagac
    19021 tggaaattgg acttggacag cgccctgaat cctgaagtga ctattgacga tgcctatgat
    19081 ttggtcatga agtcggtaga acctttgggg caagaatatt gtcaggaagt tgctcgttac
    19141 caagaagagc gctgggtgga ctttgctgct aacagtggca aggattccgg tggttatgcg
    19201 gcggacccat atcgcgtaca cccttatgtc ctcatgagct ggacaggccg tttgagcgat
    19261 gtctatacct tgattcatga aatcgggcat tctggtcaat tcatcttttc agacaatcat
    19321 caaagttact tcaatgccca tatgtcgacc tactatgttg aagcaccgtc aaccttcaat
    19381 gaattgctac tcagtgatta cttagagaac caatctaatg acccacgtca aaaacgcttt
    19441 gctctggctc atcgcttgac agacacctac ttccataact ttatcaccca cctcttggaa
    19501 gccgccttcc agcgtaaggt gtatacattg attgaagaag gagaaacctt cggagcaagc
    19561 aaactcaaca gtattatgaa ggaagttttg acagattttt ggggcgatgc cattgaaatc
    19621 gacgacgatg cagctttgac ttggatgcgc caagctcact actatatggg cttgtatagt
    19681 tacacttact ctgctggtct tgtcatctcg acagctggtt accttcatct taaaaactca
    19741 gaaactggag ctgaagactg gctcaatctc ctcaaatcag gtggtagcaa gacaccactt
    19801 gagtcagcca tgattatcgg tgctgatatt tcaacagaca aaccactccg tgataccatc
    19861 caattcttgt ctgacacagt tgaccagatt atcgcctaca gtgctgagtt gggggagtaa
    19921 ggggaataga aaaatttttt agaatgatgt ttatgggctt gttaagcgtc attctatttg
    19981 tcttagttgt agctattttc aaaaatgtcg ttgaaggtcg tgatgttaaa tttgaactta
    20041 ctgtagaact ggtattgata gttatttacg tcattttata tcagattgta tttaattgag
    20101 aattcaatat tgagtcattt aagactgcct ttttgaacag ttgctagaaa tgtagaggta
    20161 ttgaccatgt atcaagattt actaagaaaa atagcagaag aaaaaccaaa ttataaccag
    20221 gaggaaatcc agtggttgct tgatcatttg ggagatcctt ctccagaaat tcgcgatgac
    20281 cttgttttta caagctttgc tatagggatt caggaagagc tatttacaca ggagcaattt
    20341 catttcattg ctgaaggggt ttcatctgat gtaggactag ataaagagat tgataaggta
    20401 ggtctgccaa cacttgaacg ttcttttagg gcacttgttt atgcaaatct cttgtatgca
    20461 gatgccaacc agcaatcggt tttttatcag ggattacaat tagaaattcg taatgtcttt
    20521 tcaaatcaag gcttgcacta tctttcaaaa gaaaaggata caacaggttt ctcaagtcag
    20581 tatggttggg ttcatgcttt tgcacatgga gccgatttac tgacagaggt ggtctgtcat
    20641 ccagactttc ctataaacag aattcatgaa gtatttgaca tacttggcca actatttaaa
    20701 agaatgtcga ttcgctttac agatgatgag gattggcgtt tagcaagagt gatctatgaa
    20761 cctattttac aagggaagtt ggagcaagaa caagtagctt cttggataaa aactgttgat
    20821 tttccgatag aagaaaggga ggatttttcc aaattttcca actttagatc ctgtctggtg
    20881 gaagtctatg tccaacttga ccagagaaat agtttacaag atgagttgaa agaagctatc
    20941 cagtcttttc aatactagag attagctaat agttctatga ttttcaaaaa atttccaatc
    21001 aattttcttg aaaccctttc ctacttttga tagactagta tctagttttt gaaaaaagga
    21061 gaaagaaaat gaaaaaattt gttgctgagt taatcggtac gttcatgctt gtgttcgttg
    21121 ggacaggagc tgttgttttt ggaaatggtt ttgatggcct tggtcacctt ggaatcgcct
    21181 ttgcctttgg tttggcaatc gtggtggcag cctactcaat cggaactgtt tcaggtgctc
    21241 acttgaaccc ggctgtttcg attgctatgt ttgtaaacaa acgtttgtca tcttcagaac
    21301 ttgtaaacta catccttggt caggttgttg gagctttcat cgcttctggc gctgtcttct
    21361 tcctcttggc taactcaggt atgtcaactg ctagtcttgg tgaaaatgcc ttggcaaacg
    21421 gtgtcactgt ctttggtggt ttcttgtttg aagtcatcgc aactttcttg tttgtattgg
    21481 ttatcatgac tgtgacttca gaaagcaagg gcaatggccc gattgctggt ttggtaatcg
    21541 gtttgtcatt gatggcgatg attcttgtcg gattgaagat tactggactt tcagtaaacc
    21601 cagctcgtag cttggcacca gctgtcttgg taggcggcgc agcccttcaa caagtttgga
    21661 ttttcatcct tgcaccaatc gctggtggag ttcttgcagc ccttgttgca aaaaatttcc
    21721 ttggaacaga agaataattg aaactcaaaa agccttgctc ctcatcttga ggaacagggc
    21781 tttttcgtat gatactcttc gaaaatctct tcaaaccacg tcagcttcac cttgtcgtag
    21841 gtatggtt
//
LOCUS       DBEJHE010000031        20599 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC4 isolate 671759
            SAMN38261586-rid24793303.denovo.31, whole genome shotgun sequence.
ACCESSION   DBEJHE010000031 DBEJHE010000000
VERSION     DBEJHE010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261586
            Sequence Read Archive: SRR26833752
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 20599)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20599)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576136.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576136.1
            Genome Coverage       :: 109x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 19:48:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,067
            CDSs (total)                      :: 2,029
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 131
            CDSs (without protein)            :: 131
            Pseudo Genes (ambiguous residues) :: 0 of 131
            Pseudo Genes (frameshifted)       :: 64 of 131
            Pseudo Genes (incomplete)         :: 59 of 131
            Pseudo Genes (internal stop)      :: 46 of 131
            Pseudo Genes (multiple problems)  :: 32 of 131
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20599
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261586-rid24793303.denovo.31"
                     /strain="GPSC4"
                     /isolate="671759"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(91..228)
                     /locus_tag="ACL3EZ_001625"
     CDS             complement(91..228)
                     /locus_tag="ACL3EZ_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001067591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0393163.1"
                     /translation="MNPDRAEEYFCRGCQGENPEDIEFYDEQLQAEKVEDLNIRLEVK
                     N"
     gene            complement(372..521)
                     /locus_tag="ACL3EZ_001626"
     CDS             complement(372..521)
                     /locus_tag="ACL3EZ_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell envelope"
                     /protein_id="HGR0393164.1"
                     /translation="MEKFNFKNNIGQENKLLQIEIYKFTNFCKLQNYTSVNIFSKDIF
                     ETIVN"
     gene            486..605
                     /locus_tag="ACL3EZ_001627"
     CDS             486..605
                     /locus_tag="ACL3EZ_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HGR0393165.1"
                     /translation="MPDIVFEIEFFHSDSLIFFYTSDDKSNSQKSQEDFSKNK"
     gene            complement(701..2047)
                     /gene="glnA"
                     /locus_tag="ACL3EZ_001628"
     CDS             complement(701..2047)
                     /gene="glnA"
                     /locus_tag="ACL3EZ_001628"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004356 - glutamine synthetase activity
                     [Evidence IEA];
                     GO_process: GO:0006542 - glutamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HGR0393166.1"
                     /translation="MPITAADIRREVKEKNVTFIRLMFSDILGTMKNVEIPATDEQLD
                     KVLSNKVMFDGSSIEGFVRINESDMYLYPDLDTWTVFPWGDENGSVAGLICDVYTTEG
                     EPFAGDPRGNLKRALRHMEEVGFKSFNLGPEPEFFLFKLDENGDPTLEVNDKGGYFDL
                     APTDLADNTRREIVNVLTKMGFEVEASHHEVAVGQHEIDFKYDEVLRACDKIQIFKLV
                     VKTIARKHGLYATFMAKPKFGIAGSGMHCNMSLFDAEGNNAFFDPNDPKGMQLSETAY
                     HFLGGLIKHAYNYTAIMNPTVNSYKRLVPGYEAPVYIAWAGRNRSPLVRVPASRGMGT
                     RLELRSVDPMANPYVAMAVLLEVGLYGIENKIEAPAPIEENIYIMTAEERKEAGITDL
                     PSTLHNALKALTEDEVVKAALGDHIYTSFLEAKRIEWASYATFVSQWEIDNYLDLY"
     gene            complement(2084..2440)
                     /gene="glnR"
                     /locus_tag="ACL3EZ_001629"
     CDS             complement(2084..2440)
                     /gene="glnR"
                     /locus_tag="ACL3EZ_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000659547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor GlnR"
                     /protein_id="HGR0393167.1"
                     /translation="MKEKEFRRNMAVFPIGSVMKLTDLSARQIRYYEDQELIKPDRNE
                     GNRRMYSLNDMDRLLEIKDYISEGYNIAAIKKKYAEREAKSKKAVSQTEVRRALHNEL
                     LQQGRFASVQSPFGRG"
     gene            complement(2517..3044)
                     /locus_tag="ACL3EZ_001630"
     CDS             complement(2517..3044)
                     /locus_tag="ACL3EZ_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HGR0393168.1"
                     /translation="MSYFKKYKFDKSQFKLGMRTFKTGIAVFLVLLIFGFFGWKGLQI
                     GALTAVFSLRESFDESVHFGTSRILGNSIGGLYALVFFLLNTFFHEAFWVTLVVVPIC
                     TMLTIMTNVAMNNKAGVIGGVAAMLIITLSIPSGETILYVFVRVLETFMGVFVAIIVN
                     YDIDRIRLFLEKKEK"
     gene            complement(3180..4376)
                     /gene="pgk"
                     /locus_tag="ACL3EZ_001631"
     CDS             complement(3180..4376)
                     /gene="pgk"
                     /locus_tag="ACL3EZ_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004618 - phosphoglycerate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HGR0393169.1"
                     /translation="MAKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTI
                     KYIIEQGGRAILFSHLGRVKEEADKAGKSLAPVAADLAAKLGQDVVFPGVTRGAELEA
                     AINALEDGQVLLVENTRYEDVDGKKESKNDPELGKYWASLGDGIFVNDAFGTAHRAHA
                     SNVGISANVEKAVAGFLLENEIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEK
                     ADKVLIGGGMTYTFYKAQGIEIGNSLVEEDKLDVAKALLEKANGKLILPVDSKEANAF
                     AGYTEVRDTEGEAVSEGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQAG
                     TIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKVLPGL
                     AALTEK"
     gene            complement(4466..9445)
                     /locus_tag="ACL3EZ_001632"
     CDS             complement(4466..9445)
                     /locus_tag="ACL3EZ_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HGR0393170.1"
                     /translation="MKNPFFERRCRYSIRKLSVGACSLMIGAVLFAGPALAEETAVPE
                     NSGANTELVSGESEHSTNEADKQNEGEHARENKLEKAEGVAIASETASPASNEAATTE
                     TAEAASAAKPEEKASEVVAETPSAEAKPKSDKETEAKPEATNQGDESKPAEEANKTEK
                     EVQPDVPKNTEKTLKPKEIKFNSWEELLKWEPGAREDDAINRGSVVLASRRTGHLVNE
                     KASKEAKVQALSNTNSKAKDHASVGGEEFKAYAFDYWQYLDSMVFWEGLVPTPDVIDA
                     GHRNGVPVYGTLFFNWSNSIADQERFAEALKQDADGSFPIARKLVDMAKYYGYDGYFI
                     NQETTGDLVKPLGEKMRQFMLYSKEYAAKVNHPIKYSWYDAMTYNYGRYHQDGLGEYN
                     YQFMQPEGDKVPADNFFANFNWDKAKNDYTIATANWIGRNPYDVFAGLELQQGGSYKT
                     KVKWNDILDENGKLRLSLGLFAPDTITSLGKTGEDYHKNEDIFFTGYQGDPTGQKPGD
                     KDWYGIANLVADRTPAVGNTFTTSFNTGHGKKWFVDGKVSKDSEWNYRSVSGVLPTWR
                     WWQTSTGEKLRAEYDFTDAYNGGNSLKFSGDVAGKTDQDVRLYSTKLEVTEKTKLRVA
                     HKGGKGSKVYMAFSTTPDYKFDDADAWKELTLSDNWTNEEFDLSSLAGKTIYAVKLFF
                     EHEGAVKDYQFNLGQLTISDNHQEPQSPTSFSVVKQSLKNAQEAEAVVQFKGNKDADF
                     YEVYEKDGDSWKLLTGSSSTTIYLPKVSRSASAQGTTQELKVVAVGKNGVRSEAATTT
                     FDWGMTVKDTSLPKPLAENIVPGATVIDSTFPKTEGGEGIEGMLNGTITSLSDKWSSA
                     QLSGSVDIRLTKPRTVVRWVMDHAGAGGESVNDGLMNTKDFDLYYKDADGEWKLAKEV
                     RGNKAHVTDITLDKPITAQDWRLNVVTSDNGTPWKAIRIYNWKMYEKLDTESVNIPMA
                     KAAARSLGNNKVQVGFADVPAGATITVYDNPNSQTPLATLKSEVGGDLASAPLDLTNQ
                     SGLLYYRTQLPGKEISNVLAVSVPKDDRRIKSVSLETGPKKTSYAEGEDLDLRGGVLR
                     VQYEGGTEDELIRLTHAGVSVSGFDTHHKGEQNLTLQYLGQPVNANLSVTVTGQDEAS
                     PKTILGIEVSQEPKKDYLVGDSLDLSEGRFAVAYSNDTMEEHSFTDEGVEISGYDAQK
                     TGRQTLTLRYQGHEVNFDVLVSPKAALNDEYLKQKLAEVEAAKNKVVYNFASPEVKEA
                     FLKAIEAAEQVLKDHETSTQDQVNDRLNKLTEAHKALNGQEKFTEEKTELDRLTGEAQ
                     ELLAAKPNHPSGSALAPLLEKNKALVEKVDLSPEELATAKQSLKYLVALLKEDKSAVF
                     SDSKTGVEVHFSNKEKTVIKGLKVERVQASAEEKKYFAGEDAHVFEIEGLDEKGQDVD
                     LSYASIVKIPIEKDKKVKKVFFLPEGKEAVELTFEQTDSHVIFTASHFTHYAFVYESA
                     EKPQPAKPAPQNTVLPKPTYQPASDQQKAPKLEVQEEKVAFHRQEHENAEMLVGEQRV
                     IIQGRDGLLRHVFEVDENGQRRLRSTEVIQEAIPEIVEIGTKVKTVPAVVATQEKPAQ
                     NTAVKSEEASKQLPNTGTADANEALIAGLASLGLASLALTLRRKREDKD"
     gene            9770..11401
                     /locus_tag="ACL3EZ_001633"
     CDS             9770..11401
                     /locus_tag="ACL3EZ_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0005436 - sodium:phosphate symporter
                     activity [Evidence IEA];
                     GO_process: GO:0044341 - sodium-dependent phosphate
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HGR0393171.1"
                     /translation="MSINWQEILFHFLGGLGLFLYSIKTMGDGLQQAAGDRLRFYIDK
                     YTSNPFFGVLVGIGMTALIQSSSGVTVITVGLVSAGLLTLRQAIGIVMGANIGTTVTS
                     FLIGFKLGNYALPMLFIGAVCLFFTKNRTVNNIGRILFGVGGIFFALNLMSGAMAPLK
                     DLQVFKDYMIELSKNPVLGVFVGTGLTLLIQASSATIGILQNLYAGNLIDLQGALPVL
                     FGDNIGTTITAIIASLGANIAAKRVAGAHVAFNVIGTVVCVIFLVPFTVLIHWFEATL
                     NLAPEMTIAFAHGTFNITNTIVQFPFIGALAYFVTKIIPGEDEVVKYEPLYLDEHFIK
                     QAPSIALGNAKKELLHLGNYAAKAFDLSYKYIIDLDEKVAEKGHKTEEAINTIDEQLT
                     RYLIALSSEALSQKESEVLTNILDSSRDLERIGDHTEALLNLTDYLQRKNVEFSDAAL
                     KELEEVYRQTSDFIKDALDSVENNDIEKARSLVERHEAINKIERVLRKTHIKRLNKGE
                     CSTQAGVNFIDIISHYTRVSDHAMNLAEKVFAEQI"
     gene            complement(11960..13567)
                     /locus_tag="ACL3EZ_001634"
     CDS             complement(11960..13567)
                     /locus_tag="ACL3EZ_001634"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003883 - CTP synthase activity [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0006241 - CTP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HGR0393172.1"
                     /translation="MSTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPY
                     INIDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRK
                     ERRGEYLGATVQVIPHITDALKEKIKRAALTTDSDVIITEVGGTVGDIESLPFLEALR
                     QMKADVGADNVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPA
                     GQGIKNKLAQFCDVAPEAVIESLDVEHLYQIPLNLQAQGMDQIVCDHLKLDAPAADMT
                     EWSAMVDKVMNLKKQVKISLVGKYVELQDAYISVVEALKHSGYVNDVEVKINWVNAND
                     VTAENVAELLSDADGIIVPGGFGQRGTEGKIQAIRYARENDVPMLGVCLGMQLTCIEF
                     ARHVLGLEGANSAELAPETKYPIIDIMRDQIDIEDMGGTLRLGLYPSKLKRGSKAAAA
                     YHNQEVVQRRHRHRYEFNNAFREQFEAAGFVFSGVSPDNRLVEIVEIPENKFFVACQY
                     HPELSSRPNRPEELYTAFVTAAVENSN"
     gene            complement(13957..14544)
                     /gene="rpoE"
                     /locus_tag="ACL3EZ_001635"
     CDS             complement(13957..14544)
                     /gene="rpoE"
                     /locus_tag="ACL3EZ_001635"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HGR0393173.1"
                     /translation="MELEVFAGQEKSELSMIEVARAILELRGRDHEMHFSDLVNEIQN
                     YLGTSNSDIREALPLFYTELNFDGSFISLGDNKWGLRSWYGVDEIDEEIIALEENDDD
                     EVAPKAKKKRVNAFMDGDSDAIDYNADDPEDEDAYEADPALSYDDENPDDEKNEVEAY
                     DAEINEIAPDDLGEDVDLNEDDDEFSDDDAETSEE"
     gene            complement(14672..15121)
                     /locus_tag="ACL3EZ_001636"
     CDS             complement(14672..15121)
                     /locus_tag="ACL3EZ_001636"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR0393174.1"
                     /translation="MCFVPYYKVNHCEEAFAWYQDVNLVYLVDGVKLPYSQATLEAMY
                     SYLDRHGELFWIEVKEKGEWFPIGDITLSQDNLPIVIGNSAYQHRGLGKKILSALIEL
                     ARVKGWKELRVKEIYTYNYASRRCFKSLGFVENGATEKGRSFILELV"
     gene            complement(15126..15515)
                     /locus_tag="ACL3EZ_001637"
     CDS             complement(15126..15515)
                     /locus_tag="ACL3EZ_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome partitioning protein ParB"
                     /protein_id="HGR0393175.1"
                     /translation="MKVNIADLHPTQLYLSEKKLQDIQMLYQSAETIQVDPISILAFG
                     DCLLITDGHHRAYQALLAGRDTISAEWDRDGGDELYHLYAQACEERKIYSVFDLEDRI
                     LAQDGYEAKWYNWCDGFNQAATLLLKR"
     gene            complement(15543..16193)
                     /locus_tag="ACL3EZ_001638"
     CDS             complement(15543..16193)
                     /locus_tag="ACL3EZ_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HGR0393176.1"
                     /translation="MKDKQTFLMKGSFALLLFVILGYMVKFYPEMLVNFDQSIQTAIR
                     GDLPDYLTILFRSLTRLIDIPVIITWVVITAFVFYRKRWKIESFFMLGNLALAGLLIV
                     TFKNIYQRPRPAILHLVEEKGFSFPSGHSLAVTLMVGTLIVILSQRIKTPVWRKIVQI
                     VLGLYLVSVLVSRVYLGVHYPSDVLASLCVGLGVLFIEFPFYDKLRFQWRFKGKQK"
     gene            complement(16183..16746)
                     /locus_tag="ACL3EZ_001639"
     CDS             complement(16183..16746)
                     /locus_tag="ACL3EZ_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HGR0393177.1"
                     /translation="MTNTRRLSTIAILSAISFVLMYFDFPLLPAASFLKIEFSILPVL
                     VGLVVMDLPAALGVLLLRSLLKLLLNSQGVNTYIGLPMNIVALGVFVIVFALIWKKER
                     TTLRFLLGSLAGTVGLTLAMLVLNYVYAVPLYAKFANFDIGKILGLSNYLMTMVLPFN
                     LIEGVIFSVSFWLLYVLLKPTLKHYER"
     regulatory      complement(16911..17145)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(17199..17702)
                     /locus_tag="ACL3EZ_001640"
     CDS             complement(17199..17702)
                     /locus_tag="ACL3EZ_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (cytidine(34)-2'-O)-methyltransferase"
                     /protein_id="HGR0393178.1"
                     /translation="MTNHIVLFEPQIPQNTGNIARTCAATNSPLHIIKPMGFPIDDRK
                     MKRAGLDYWDKLEIYFYESLEDFISQMKGKLYLISKFAEKIYSEVDLSTDEDHYFLFG
                     REDKGLPEDFMREHPEKALRIPMNDEHVRSLNVSNTVCMIVYEALRQQNFAGLELVHT
                     YEVDKLK"
     gene            complement(17895..18725)
                     /locus_tag="ACL3EZ_001641"
     CDS             complement(17895..18725)
                     /locus_tag="ACL3EZ_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HGR0393179.1"
                     /translation="MQAKLIGYQHRDTVIHRLSGAGKLLFFILVSLAAMISYDTRMLL
                     LIAIFSVFLLYLSEIRFKDVSFVAVFATVFAVLNVLMVYLFSPEYGVGLYGERSVIWQ
                     GIGVYTLTSQELFYLLNLAIKYLCTIPLAIIFLMTTHPSQFASSLNQIGVPYKIAYSV
                     SLTLRYIPDLQEEFFTIKMSQEARGMELSKKASLMQRIKGNLLIITPLIFSSLERIDT
                     IATAMELRRFGKEKKRTWYSYQALKKGDYITLLLATLFLVVSLLLILQNQGRFYNPWK
                     "
     gene            complement(18710..20392)
                     /locus_tag="ACL3EZ_001642"
     CDS             complement(18710..20392)
                     /locus_tag="ACL3EZ_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0393180.1"
                     /translation="MKEAIIEWKDFSFRYETQQEPTLQGIDLTIYKGEKVLIVGPSGS
                     GKSTLGQCLNGIIPNIYKGQTYGEFLIKGQVAFDMSIYDKSHLVSTVLQDTDGQFIGL
                     SVAEDLAFALENDVTALDEMKGRVYKWAEKLDLLPLLDQRPQDLSGGQKQRVSLAGVL
                     IDESPILLFDEPLANLDPKSGQDIIELIDQIHKEEGTTTLIIEHRLEDVLHRPVDRIV
                     LISDGRILFNGSPDQLLATDLLTQNGIREPLYLTTLRQLGVDLVKEEQLANLDNMSIS
                     KGQVQLQNELAKETPELQSLFKLEDVSFSYDDRPILKSLHLDIKKGEKIAIVGKNGAG
                     KSTLAKAISSFIQTEGRYLWEKQDIKGDSVAERAERVGYVLQNPNQMISTNMIFDEVA
                     LGLRLRGVDEKEIETRVYETLKICGLYEFRNWPISALSFGQKKRVTIASILVLGAEII
                     LLDEPTAGQDQKNYTEIMEFLEELHQKGHTIVMITHDMQLMLDYSDRVLVMVDGELIA
                     DTVPASLLSDPELLVKANLKETSIFNLAKKLDVDPLDLTAFYKERREGCKLN"
BASE COUNT         5961 a         4562 c         3770 g         6306 t
ORIGIN      
        1 tatgtgcttc aagtatataa aaaggcgtaa aaatacgcct atagataatg gggttgaaat
       61 aggtttattg ttgatgagat tgtagataat tcaatttttt acttccaatc gaatattcaa
      121 atcctccacc ttttctgcct gtaattgttc atcataaaat tcaatatctt caggattttc
      181 cccttggcaa cctcggcaga aatattcttc cgctcgatca ggattcaaaa atcgacaagc
      241 acaaacaaaa cagtcgccat catcatttat tgagataata tagtagattg aaataagatg
      301 taaacaaatc gattaggaaa gttaaattag tttctagaaa tttttagcag atgtagtgta
      361 ctattctagt ctcaatttac tatggtttca aatatatctt tcgaaaaaat atttacagat
      421 gtgtaatttt gaagcttgca aaagttagta aacttgtaga tttcgatttg aagtaacttg
      481 ttttcttgcc cgatattgtt tttgaaattg aatttttcca tagtgactcc ttaattttct
      541 tctacacgtc tgatgataaa tctaattcgc aaaagagtca agaggatttt tcgaaaaata
      601 aatagcgacc gaaatcgcta ttttaagggt tataggtatt tgatggctta gactgctgtg
      661 tgactgttta cccacaggca atctttcttc tatattagta ttagtaaagg tctaaataat
      721 tatcaatttc ccattgtgaa acgaaggttg cataacttgc ccattcgatt cgtttggctt
      781 caaggaagct agtgtagatg tgatctccga gagcagcttt aaccacttca tcttctgtca
      841 aagctttcaa agcgttgtga agagttgatg gaaggtctgt aataccagct tccttgcgct
      901 cttctgctgt catgatgtag atattttctt cgataggagc tggtgcttcg attttatttt
      961 caataccata caaaccaact tccaaaagaa cagccatagc aacgtaaggg ttcgccattg
     1021 gatccactga acgcaactca agacgagttc ccataccacg tgaagcaggt acgcgcacaa
     1081 gtggcgaacg gttacgacca gcccaagcaa tgtaaacagg cgcttcataa cctggaacca
     1141 aacgtttgta tgagttaact gttgggttca tgatggcagt atagttgtaa gcatgcttga
     1201 tcaaaccgcc taggaaatgg taagctgttt ctgacaactg cattcctttt ggatcatttg
     1261 gatcaaagaa ggcgttattt ccttctgcat caaacaagga catattacag tgcatacctg
     1321 atccagcaat accaaatttt ggcttcgcca taaatgttgc gtaaagtccg tgtttgcgag
     1381 caatggtttt aacaacaagt ttaaagattt gaatcttatc acaagcacgg agaacttcat
     1441 cgtacttaaa gtcaatctca tgctgtccaa ccgcaacctc gtggtgactc gcttctactt
     1501 caaatcccat tttggtcaag acattcacaa tctcacgacg tgtgttgtcc gcaaggtcag
     1561 taggtgccaa atcaaagtag ccacccttgt cattcacttc aagtgttggg tccccatttt
     1621 catccaactt aaataggaag aattctggct ctggaccaag gttgaaggat ttgaatccaa
     1681 cttcttccat gtgacgaaga gctcgtttca aattaccacg agggtcaccc gcaaatggtt
     1741 caccttctgt tgtatagaca tcacagatca gacctgcaac acttccattt tcatctcccc
     1801 aagggaagac tgtccatgta tccaagtccg ggtacaagta catatccgac tcattgatac
     1861 gtacaaaacc ttcaatagaa gatccatcaa acataacctt gttcgacaag accttatcta
     1921 actgttcatc tgtagcagga atttcgacgt ttttcatggt tcccaaaata tctgagaaca
     1981 taagacgaat aaaggtaaca tttttttcct tgacttcacg acgaatatct gcagctgtga
     2041 ttggcataag ttttctcctt aatctatgac tacttgcggt tgcctaaccg cgaccaaaag
     2101 gtgactgtac tgaagcaaaa cgcccctgtt ggaggagttc attgtgaagt gcacgacgta
     2161 cttcagtctg actaaccgct ttcttggatt tcgcttcacg ttcagcatat tttttcttaa
     2221 tggcagcgat attataacct tcagagatat aatctttgat ttcaagcaga cgatccatgt
     2281 cattcaagga atacatgcga cgatttcctt cgtttcgatc gggcttgatc aactcttgat
     2341 cttcataata acgaatctga cgcgccgata aatcggtcaa cttcataaca ctgccgatag
     2401 gaaaaacagc catatttcgg cgaaattctt tttccttcat ttacaatttc cttctttctg
     2461 tctattatag tctaaaaaaa gacaaacgtc aattgataat gttataaaat gtaacattat
     2521 ttttcttttt tctctaaaaa gagacgaata cgatcaatat cgtaatttac gataattgcg
     2581 acaaaaactc ccataaacgt ttctaataca cgcacaaaca cgtacaaaat tgtctcacca
     2641 cttggaattg atagggtaat gattaacata gctgctacac caccaataac ccctgctttg
     2701 ttattcatgg ctacatttgt cataatggtt aacatggtgc agattggaac aactaccaag
     2761 gtcacccaaa aggcttcgtg gaaaaaggta tttaataaga aaaagaccaa ggcatagagt
     2821 ccaccgatac tatttcctag aatacgcgaa gtcccaaaat gaacactctc atcaaaactc
     2881 tccctcaggc taaaaacggc tgtcaaagca ccaatttgaa gacctttcca gccaaaaaag
     2941 ccaaaaatca agagaactag aaaaacagca atacctgttt taaaggttcg cataccaagt
     3001 ttgaactggg atttatcgaa tttatatttt ttaaaataac tcataatctc aactttctat
     3061 ttccatttta tcataaatcg gtgattttta tgagtaatag ttgagaggaa gcgtttttat
     3121 tttaagcaaa agaaaagagg aactttcatc cctctcttct ttgatttgtt tataaaatct
     3181 tatttttctg tcagggctgc aagtcctgga agaaccttac cttcaagaag ttccattgat
     3241 gctccaccac ccgtactaat ccatgagaac ttgtctgcac ggccaaggtt aatcgctgcg
     3301 gcagctgagt caccaccacc gatgattgat ttaactcctg gttgtttcac gatagcgtcc
     3361 atcacaccga ttgtaccagc ttggaaatct gggttttcaa atacacccat aggtccgttc
     3421 catacaactg ttttggcacc agtcaaagct tcgtcaaatt tggcgataga ttttggaccg
     3481 atgtcaagac caaggaagcc ttcagaaact gcttcacctt cagtgtcacg cacttcagtg
     3541 taaccagcaa atgcgttagc ttcttttgag tcaactggca agatcaattt accatttgct
     3601 ttttcaagaa gagctttcgc aacatccaat ttgtcttctt ctacaagtga gttaccgatt
     3661 tcgatacctt gtgctttgta gaatgtgtaa gtcatcccac caccgataag gactttatca
     3721 gctttttcaa gcaagttttc gataacaccg atcttgtctg aaacttttga accaccaagg
     3781 atagccacga atggacgttc tggagtttca actgcttctt ggatgtaggc aatttcgttt
     3841 tcaagaagga aaccagcaac tgctttttca acgtttgctg agataccaac gttagatgcg
     3901 tgtgcacggt gagctgtacc gaatgcatcg tttacgaaga taccatctcc aagtgatgcc
     3961 cagtatttac caagttcagg atcgttttta gattctttct tgccgtcaac atcttcgtaa
     4021 cgagtgtttt caaccaagag aacttgtcca tcttcaagag cgttgattgc cgcttccaat
     4081 tcagcaccac gagtgacacc tgggaaaaca acatcttgac caagttttgc tgccaagtca
     4141 gctgctacag gagcaagtga tttaccagct ttatcagctt cttctttcac acgtccaagg
     4201 tgagagaaaa gaattgcacg tccaccttgt tcgatgatgt acttaatagt tggaagagct
     4261 gctgtgatac ggttatcgtt agtgattacg ccatctttca atggtacgtt gaagtcaaca
     4321 cgaacgagga cttttttacc tttcaagtca acgtctttaa cagtaagttt tgccatgtta
     4381 caaaaactcc tttatttatt ttattcgaaa ctattatatc acactttgga aatataagga
     4441 aagatttcac aagatttttc gatatttaat ctttatcttc tcttttccgt ctcaaggtca
     4501 aggctaaact agcaagacca aggctggcta agcctgctat tagggcttca ttagcatcag
     4561 ctgttcctgt atttggcaat tgtttgcttg cttcttctga tttaactgct gtattttgag
     4621 ctggtttttc ctgtgtagct actactgctg gtactgtttt tacttttgtt ccaatttcaa
     4681 caatttctgg aatcgcttct tggatgactt ctgttgaacg aagacgacgc tgaccgtttt
     4741 catcaacttc aaagacatgt cttaacagtc catctcgtcc ctgtatgatg actcgttgtt
     4801 ccccaactag catctcagca ttttcatgct cttgacgatg aaaggcaacc ttttcctctt
     4861 gaacttccaa tttaggagcc ttttgttgat cagaagccgg ttgataagta ggttttggaa
     4921 ggactgtgtt ttgtggtgct ggtttagcag gttgtggttt ttcagcagat tcataaacaa
     4981 aggcataatg agtaaagtga gatgctgtaa agataacatg actatccgtt tgttcaaaag
     5041 tcaattctac tgcctctttg ccttcaggta agaaaaatac tttcttaact ttcttatctt
     5101 tttcaattgg gattttcaca atagaagcat aagagagatc aacatcttga cctttttcat
     5161 ccaaaccttc tatttcaaag acatgagcat cttctccagc aaagtatttc ttctcttcag
     5221 cacttgcttg aacacgctct actttcaaac ccttgatgac agtcttctct ttatttgaga
     5281 agtgtacttc aacacctgtt ttactatcag aaaagactgc tgacttgtct tctttcaata
     5341 aagcaaccag atattttaga ctctgtttcg ctgttgcaag ctcttctgga ctcaaatcta
     5401 ctttttcaac caaggccttg tttttctcaa gaagcggagc tagggcagaa cctgaaggat
     5461 ggtttggttt ggcagccaag agttcttgag cctcacctgt taagcgatca agctctgtct
     5521 tttcttccgt aaatttctct tgaccattca gagctttatg agcttctgtc aatttattaa
     5581 gtcggtcatt gacttgatct tgggtgctag tttcatggtc tttcaacact tgttcggccg
     5641 cttcaattgc tttcaagaaa gcttctttta cttctggtga agcaaagtta tagaccacct
     5701 tgttcttagc agcttcaact tctgctaatt tttgtttgag gtactcatcg ttcaatgctg
     5761 cttttggaga taccaaaaca tcaaagttga cttcatgacc ttggtaacga agcgtcaagg
     5821 tttgacgacc agtcttttga gcatcgtaac cagaaatttc aactccctca tcagtaaagg
     5881 aatgttcttc catggtgtca ttgctataag ccactgcaaa gcgtccttca gacaagtcta
     5941 agctatcacc aactaggtaa tcttttttcg gttcctgact tacttcaatt cccaaaatag
     6001 ttttcggact tgcttcatct tggccagtga cagtcactga caaattagca tttactggtt
     6061 gtcccaaata ttggagagta agattctgtt ctcccttatg atgcgtatca aaacctgata
     6121 ctgatacacc tgcgtgagtt aggcgaatga gttcgtcctc agttcctcct tcatactgaa
     6181 ctcgaagaac accacctcta aggtccaaat cctccccttc ggcgtagctt gttttcttag
     6241 gtcctgtttc taggctgact gacttgattc ttctgtcatc ttttggaacg gaaactgcta
     6301 ggacattact aatttccttg cctggcaact gggtacgata ataaagaaga ccagattgat
     6361 ttgtcaaatc caatggtgca cttgctaggt ctcctccaac ttcgctcttc aaggttgcga
     6421 gcggagtttg agaatttgga ttatcataaa cggtaatagt tgctccagcc ggtacatctg
     6481 caaagccaac ttgtaccttg ttattgccta gagaacgggc tgcagccttg gccatcggaa
     6541 tattgacact ctcagtatca agcttttcat acattttcca gttatagata cgaatagcct
     6601 tccatggagt tccattgtca gaagtgacaa cattcaagcg ccagtcctga gcagtgattg
     6661 gtttatcaag agtgatatct gtcacgtgtg ctttgttacc acggacttcc ttagctagct
     6721 tccactcacc atctgcatct ttataataaa ggtcaaagtc tttagtgttc atcaagccat
     6781 cgttaacaga ctcaccacca gctcctgcat gatccatgac ccatctaaca acggtacgtg
     6841 gcttggtcaa acgaatatcc acactaccac tcaactgagc tgaagaccat ttatctgaca
     6901 agctagtaat ggtaccgttc aacatacctt caataccttc tccaccttca gtcttaggga
     6961 aagtactatc aataactgtt gcacctggaa cgatattttc agctagtggt tttggtaggc
     7021 tggtatcttt tacagtcata ccccaatcaa aggttgtggt tgcagcttct gaacgaactc
     7081 catttttacc gactgctaca accttcagtt cttgagttgt accctgagca cttgctgagc
     7141 ggctaacttt tggtagataa atagttgtag aagatgagcc agttagtaat ttccagctgt
     7201 ctccatcttt ttcataaact tcatagaaat ctgcatcctt gttgccttta aattgcacaa
     7261 ctgcttccgc ttcttgggca tttttaagag attgtttcac tacagaaaag cttgtcggcg
     7321 attgtggctc ttggtgattg tccgagatag ttaattgtcc taggttgaac tgataatctt
     7381 ttacagcacc ttcatgctcg aaaaatagtt tgactgcata gatggtttta cctgctagtg
     7441 agctgagatc aaattcttca tttgtccagt tgtcagaaag ggttagctct ttccatgcat
     7501 ctgcatcatc gaatttgtag tctggagttg tagagaatgc catataaact ttagaacctt
     7561 ttcctccctt gtgggcaaca cgaagtttgg tcttctcagt tacttctaac ttagtagaat
     7621 aaagtctcac atcctgatct gtcttaccgg ctacatcacc agagaattta agggaatttc
     7681 cgccattata ggcatctgta aaatcatatt ctgcacgaag tttttcccct gttgaagtct
     7741 gccaccagcg ccatgttgga agaacacctg atactgaacg ataattccac tcagaatcct
     7801 tagaaacctt accatctacg aaccattttt taccatgacc tgtattaaaa gaagtagtaa
     7861 aagtattacc taccgctggc gtacggtccg caactaggtt agcaatacca taccaatctt
     7921 tgtcacctgg tttttggcca gtagggtctc cttgataacc tgtaaagaag atatcttcat
     7981 ttttatgata atcttcacca gtttttccta aacttgtaat ggtatctggg gcaaataaac
     8041 caagagaaag gcgcaatttc ccattttcgt ctaaaatgtc attccactta acctttgtct
     8101 tgtaggaacc accctgttgc aattccaaac ctgcaaatac atcataagga ttacgaccaa
     8161 tccagttggc agttgcaata gtgtaatcat ttttagcctt atcccagtta aagttagcaa
     8221 agaagttatc tgccggaacc ttatctcctt ctggttgcat gaattggtag ttgtattctc
     8281 ccaaaccatc ttgatggtaa cgtccatagt tataggtcat ggcatcgtac caagaatact
     8341 tgattggatg gtttacctta gcagcatatt ccttgctata gagcataaac tggcgcatct
     8401 tttctccaag aggtttaacc aaatctccag ttgtttcttg gttgatgaaa tagccatcat
     8461 agccataata cttggccatg tctaccaatt tacgggcaat tgggaagcta ccatctgcgt
     8521 cttgcttcaa agcttcagca aatctttctt gatctgcaat actattagac cagttgaaga
     8581 agagtgtacc gtatacagga accccgttac ggtgacctgc atcaataacg tcaggagttg
     8641 gtacgagacc ttcccagaag accattgaat ctagatattg ccaatagtca aaagcatagg
     8701 ccttgaactc ttctccacca acagaagcat ggtcttttgc tttagaatta gtgtttgata
     8761 aggcttgaac ttttgcttcc ttgctagctt tttcattgac taaatgacct gtccgacgtg
     8821 aagcgaggac aacagatccg cggttaatag catcatcttc acgagcacct ggttcccatt
     8881 ttaacaattc ttcccaagaa ttaaatttga tttcctttgg ttttaatgtt ttttctgtat
     8941 ttttagggac atctggctgg acttcttttt cagtcttatt agcttcttct gctggtttag
     9001 actcatcccc ttggttagtt gcttcgggct ttgcttctgt ttccttgtca gacttaggtt
     9061 ttgcttctgc agatggtgtt tctgcaacca cctcacttgc tttttcctct ggtttagctg
     9121 cgctagctgc ttctgcagtt tcagtagttg cagcttcatt gcttgctggc gaagcagttt
     9181 cagatgctat cgctactcct tctgcctttt ctagcttgtt ttctctagca tgttcccctt
     9241 cattctgctt atcagcttca ttggtcgaat gctcactctc tcctgaaaca agctctgtat
     9301 tagctccgct attttcagga actgcagttt cttcagccaa ggctggacca gcaaataaaa
     9361 cagcaccaat catcagcgag caggctccta ctgataactt acgaatactg taacgacaac
     9421 gtctttcaaa aaatggattc ttcattttct cctcctaaaa gattgatttt gttgttttca
     9481 agaaagcgct ttatattctg tggtttttta tcaaactcta gaaccatgat aatcacattt
     9541 ttatcctaaa acatttttat cctaaaacat ttttatccta aaacattttt agacaaaaaa
     9601 caatagctgc tttcataaat ctaaaataag gttaaaaact cttaaaaata atacacttat
     9661 caattataat tttcttttac aaacttgacg ttaacacttg ttagatttac ttttatcctt
     9721 taaaatagaa taggagatat tccgcgatta tttttcggag gaaaaagaaa tgtccattaa
     9781 ttggcaggaa attttatttc actttttagg tggtctgggg ctattcttat atagtatcaa
     9841 gaccatggga gacggtttgc aacaagctgc tggagatcgc cttcgttttt acattgacaa
     9901 atatactagt aatcctttct ttggagttct ggttggtatt gggatgactg ctctaattca
     9961 gtctagttct ggtgtaacag ttattacagt cggcctggtc agtgccggtc tcttaacctt
    10021 acgtcaggct atcgggattg tcatgggtgc taatattggg acaactgtca catcctttct
    10081 catcggtttt aaattaggta actatgccct acctatgctc tttatcggtg ccgtctgtct
    10141 cttttttacg aaaaatcgga cagtcaataa tatcggacgc atcctctttg gtgtcggtgg
    10201 tatctttttt gccctcaatc tcatgagcgg cgcaatggct ccactcaagg atttacaggt
    10261 ctttaaggac tatatgattg agctaagtaa gaatcctgtt ttgggtgtct ttgtcggtac
    10321 tggcttgacc ttgctaattc aagcttcttc ggctaccatt gggattttac aaaacctcta
    10381 cgccggcaat ctaattgacc tacagggagc tttgccagtt ctatttggtg acaatatcgg
    10441 gacaaccatt acagccatca ttgcctcttt aggggctaat attgcagcta aacgggtagc
    10501 aggagctcat gttgccttca acgttatcgg aacagtcgtc tgcgttattt ttctagttcc
    10561 ttttactgtc ctgattcatt ggtttgaagc tacgctaaat ctagcaccgg aaatgaccat
    10621 cgcctttgct cacggaacct ttaatattac caacaccatt gtccaatttc catttatcgg
    10681 agctctggct tactttgtaa ccaagattat tcctggagag gacgaggttg tcaaatacga
    10741 acccttatat cttgatgaac atttcatcaa acaggcccca tctatcgctc taggaaatgc
    10801 taagaaagag ctcttgcact taggaaacta cgctgctaaa gcctttgacc tttcctataa
    10861 gtacatcatt gacttggatg aaaaagttgc tgaaaaaggg cataaaaccg aagaagcaat
    10921 taacaccatc gatgagcaat taacacgtta tctcattgcc ctttcaagcg aagctctcag
    10981 ccaaaaagaa agtgaagtgc ttaccaatat ccttgattcc tcccgtgatt tggaacggat
    11041 tggagaccac acggaggctc tactcaatct gactgactat cttcaacgga aaaatgttga
    11101 attttctgat gccgccttga aagaattaga ggaagtttac cgccaaacta gtgactttat
    11161 caaagatgct ctggatagtg tggaaaacaa tgatattgaa aaagcacgca gtcttgtaga
    11221 acgtcatgaa gcaatcaata agatagaacg tgttctcaga aaaacccaca tcaaacgtct
    11281 caacaaaggc gaatgttcaa cacaagctgg ggtcaacttt atcgacatca tctcacacta
    11341 cactcgtgta tcagaccacg ctatgaacct tgctgaaaag gtttttgcag aacaaatcta
    11401 agaaccaaga agctatccat cataattgga tggcttttta ctttttccta agcaagacta
    11461 ggctgaatga aactgaaaga gtattctgta gatatatagt atattgaaac tagaatagta
    11521 cacctctatt tctaaaacat tcttagaaat cgatttgact gtcctgatcg atttgtcctg
    11581 ttattatttc attttactat agtggattaa attaaaaaag tataatgtat tgaatctata
    11641 acagtacatc ttgactgcta aaatatttct ataaattaat ttgactttcc tgatagagat
    11701 gttcacatct tatttcaatt cactatacaa tccagttcct aaaactttgc tagaaattga
    11761 tttggctttc cgaattaatt tgttcaaatt ttatttcatt tcaatatact gataaatcca
    11821 ttcactagca cagggcaaga gggagtcgct atttatttca acggtagcag gtacatacag
    11881 aggactccta tctcagatat actgcaatat catcgtatgc aaaaaacctc tgagattttt
    11941 ctcaaaggtt ctgattttgc taattgctgt tctcaaccgc tgcagtaaca aaggcagtgt
    12001 agagttcttc tggtcggttt ggacggcttg acagttcagg gtgatactga caagctacaa
    12061 agaatttatt ttcaggaatt tccacgattt ctaccaaacg attgtctgga gaaactcctg
    12121 aaaagacaaa acctgctgcc tcaaactgct cacggaaggc attattaaac tcataacggt
    12181 gacggtgacg gcgttgcacc acttcttgat tgtgataagc agcagcagcc ttagagccac
    12241 gtttcaactt agacggataa agtcccaaac gaagggttcc acccatatcc tcaatatcaa
    12301 tctgatcacg catgatatca atgatagggt attttgtttc tggtgcaagc tctgcagaat
    12361 tggcaccttc aagacctaaa acgtgacgag caaactcgat acatgtcaac tgcattccca
    12421 agcagactcc caacattgga acatcatttt cacgcgcata gcggatggct tggattttcc
    12481 cttctgtacc acgttgacca aaaccacctg gtacgatgat cccgtccgca tcagacaaga
    12541 gttctgctac attctctgct gtcacatcat tggcattgac ccaattgatt ttaacttcta
    12601 catcattgac atagccagag tgtttcaagg cttcgaccac tgagatatag gcatcttgca
    12661 actccacata cttaccaaca agggaaatct taacttgttt cttgaggttc atgaccttgt
    12721 ccaccatggc tgaccattct gtcatatccg ctgctggtgc gtctaatttc aaatgatcac
    12781 aaacaatttg gtccatccct tgtgcctgca agttcagtgg aatttggtaa aggtgttcaa
    12841 catccaacga ttcgataacg gcttctggtg ccacatcaca gaactgggcc agtttatttt
    12901 taattccttg accagctggc tcttctgtac gaataaccaa catatttggt tggattccca
    12961 agccacgcaa ttctttgaca gagtgttggg ttggtttggt tttcatttca ccagcagcct
    13021 tgaggtaagg aagcaaggtt gtatggatat acatgacatt atccgcaccc acatctgcct
    13081 tcatctgacg aagagcctct aggaatggca aggactcgat atctcctact gttccaccaa
    13141 cctctgtgat aatgacatca gagtcggtcg ttagagcggc acgcttgatt ttttctttca
    13201 aagcatctgt gatatgagga atgacttgaa cagttgcccc aaggtattct ccacggcgtt
    13261 ctttacgaag aacttcactg taaattttcc cagttgtcac gttggaatat ttgttgagat
    13321 tgatatcgat gaaacgttca tagtgaccca agtccaaatc tgtctcagct ccgtcatctg
    13381 tcacaaaaac ttccccgtgc tggtaaggac tcatggttcc cggatcaata ttgatataag
    13441 ggtcaaactt ttgaatggtt actttgagac cacgattttt caagagacgg cctagactcg
    13501 ctgccacaat ccctttccca atggacgata ccacaccacc agttacaaaa atatatttcg
    13561 tagacataga ttcctctttc taaaatgctc aaggtcttgt taactacgag gggatataga
    13621 aaacaagacc ctactaataa gaataatctg ggacgactgc accagattca caactaatac
    13681 tcttcgaaaa tctcttcaaa ccgcgtcaac gtcgccttgc cgtagatatg tgttcctgac
    13741 tttgtcagtc ttatctacaa cctcaaaaca gtgttttgag cagcctacgg ctagtttcct
    13801 agcttgctct ttgattttca ttgagtataa aatacaagaa gataacttct tgaaaaaaca
    13861 aaaatagctc cctaagaact agggagcccc gacctctaaa agaggtgccc aaacaatatg
    13921 atacctaaaa ataggataat tgtcaatagc taactcttat tcctcgctgg tttcagcgtc
    13981 gtcatctgaa aactcgtcgt cgtcttcgtt gagatccaca tcttctccca agtcatctgg
    14041 agcgatttcg ttgatttctg catcataagc ttccacttca tttttttcat catctggatt
    14101 ttcatcatcg tatgaaagag ctggatctgc ttcgtatgca tcttcgtctt ctggatcatc
    14161 tgcattgtag tcaatggcat ctgaatcacc atccataaag gcattgacac gttttttctt
    14221 agcttttggt gctacttcat cgtcgtcatt ttcttcaaga gcgatgattt cttcgtcgat
    14281 ttcgtccaca ccataccatg aacgaagacc ccatttgttg tccccaagtg agatgaagct
    14341 accgtcaaag ttcaactctg tgtagaacaa aggcaaagct tcgcggatat cgctgtttga
    14401 tgttccaagg tagttttgaa tttcgtttac aagatcgcta aaatgcatct catgatcgcg
    14461 accacgaagt tccaagatag cacgcgctac ctcaatcata gatagttcac ttttttcttg
    14521 cccagcaaat acttctaatt ccaaagcgtt tctcctcatt tatactacta tcgccagagc
    14581 gaacagactc tgacctcatt ttatcattta ctctttattt tacgataatt ttgcggaata
    14641 gtcaaaggtt aagggggaga aagtggcagg attagactaa ttccaatata aaactccttc
    14701 ctttttctgt tgctccattt tccacaaatc caagcgactt gaaacacctc ctagaagcat
    14761 aattgtaggt gtagatttcc ttgactctca attctttcca tccttttact cgagccaatt
    14821 caatcaaagc acttagaatc ttttttccaa gtcctcgatg ttggtaagcg gaattcccaa
    14881 tcacaatggg gagattatcc tgagatagtg taatatcccc aattggaaac cattctccct
    14941 tctccttgac ttcaatccaa aaaagctcac catgccgatc caaataggaa tacatggctt
    15001 ccaaggtcgc ttgactgtaa ggaagcttca ccccatctac gaggtaaacc aagttcacat
    15061 cctgatacca agcaaaagct tcctcacaat gattgacctt ataataagga acaaaacaca
    15121 atgcactacc ttttcaacaa aagagttgct gcttgattaa aaccatcaca ccagttatac
    15181 cattttgctt catacccatc ttgagctagg atacgatctt ctaaatcaaa aacagagtaa
    15241 atctttcttt cctcgcaagc ttgcgcatag agatgatata gttcatcacc accatctcta
    15301 tcccactcag cagaaatcgt atcccgacct gccaataaag cctgataagc cctgtgatgc
    15361 ccatctgtaa tcagcaaaca atctccaaag gcaagaatac tgattggatc gacttggatt
    15421 gtttctgccg actggtaaag catctgaata tcttgcaact tcttttctga taaatatagt
    15481 tgagtcggat gaagatctgc tatattgact ttcatttctt tctcctcaag ggaattcgat
    15541 actcacttct gtttgccttt aaatcgccat tggaagcgga gcttgtcata gaagggaaac
    15601 tcgataaaca ggactcccaa gcccacacag agactggcaa ggacgtctga tgggtaatga
    15661 actcccagat agactcttga taccagcaca ctgactaggt agaggccaag gacgatttgt
    15721 acgatttttc tccagactgg agttttaatt cgttgactga gaatgacaat cagagtacct
    15781 accatcaaag ttacagccag agaatgccca cttgggaagg aaaatccctt ctcttccacc
    15841 agatgtaaga tagctggtcg tgggcgctgg tagatatttt taaaggtcac gattaaaaga
    15901 cctgccaaag ccagatttcc cagcatgaag aaactttcta tcttccatcg cttacgataa
    15961 aagacaaaag ctgtaatgac aacccaagtg ataatcactg ggatatcaat cagacgtgtg
    16021 agggatcgaa aaagaatagt caaataatct ggtaagtctc ctcgaatggc agtctgaatc
    16081 gattggtcaa aattgaccaa catttcaggg taaaatttga ccatatagcc aagaataacg
    16141 aaaagtaaaa gggcaaaact gcccttcatt aaaaatgttt gtttatcttt catagtgttt
    16201 taaggttggt ttcaaaagga cgtacaacaa ccagaatgaa acggaaaaga ttacaccctc
    16261 aatcaagtta aaaggtaata ccatggtcat taggtagttg gaaagtccca aaatttttcc
    16321 aatatcaaag ttagcaaact tagcgtacaa aggaacagca taaacatagt tgagaaccaa
    16381 catggccaag gttaaaccaa cagttccagc tagagagcct agtaggaaac gaagggttgt
    16441 ccgttccttt ttccaaatca aagcaaatac gatgacaaaa actcccaaag ctacgatatt
    16501 catcggcaaa ccaatgtaag tattcactcc ttggctgtta agaagcaatt tcaagagtga
    16561 gcgaagcaag agcactccta gagcagcagg caaatccatg accaccagac ccacaaggac
    16621 tggcaagata ctaaattcga tcttgaggaa agatgccgct ggtaaaagcg gaaagtcaaa
    16681 gtacatcagc acaaatgaga tggctgataa aattgcaatg gtcgaaagtc gacgtgtgtt
    16741 tgtcataaca ggttcctcca attttctata aaatcagaag aagttggaaa ggattcctct
    16801 atctattctc actttttata tcccaaaagt tccctcttac tctattaaag aaaaacaaag
    16861 caagtggtta caatccggct ataaatctat caaaacagac aaagctattc tttcgtcttc
    16921 tcccatccag actatactgt cggttgtgga atctcaccac atcagcttgc gctcgcggac
    16981 ttctttaaag ggaaagaaat agagattttt cttttagact aggcgacaag ctgtaggcat
    17041 aacttctggt taggcaaagc ttgtcaacaa agtataaaag gaaaagatca tttcctagtt
    17101 aaagtcaccg ccggtcggga atcacaccct gccctgaaga ctcttttatc ataacaaaaa
    17161 acgcttgcaa gcgcaagcat tttgttcatt ttcatttttt atttcaattt atccacttca
    17221 taggtatgga cgagctcaag acctgcaaag ttctgctggc gaagagcctc atagacaatc
    17281 atgcagacgg tattagacac attgagactg cggacatgtt catcattcat gggaatacgg
    17341 agagccttct caggatgttc tcgcataaaa tcttcaggta agcccttgtc ttcacgtcca
    17401 aagagaaaat aatggtcctc gtcagtcgat aaatccacct cagaatagat tttttccgcg
    17461 aatttcgaaa tcagatagag ttttcccttc atctgagata tgaaatcttc taaactctcg
    17521 taaaaataaa tctctagctt atcccagtaa tccaatccag cccgcttcat cttgcggtca
    17581 tcaataggaa agcccatagg cttgatgatg tggaggggag aattggtcgc agcgcaagta
    17641 cgcgcgatat tgcctgtatt ttgtggaatt tgaggttcaa ataatacaat gtgatttgtc
    17701 atgacttgct tcctttcacc attgcaaaaa aatagccaca ctgcccggag tcaagctcag
    17761 caaacagcgt ggttaaggca tcgttaactt acctcacaac aggtttgaag taaatcagcg
    17821 aaactacttt cttagtataa cactttcaga atcattgtca atagaaatga cttgattttt
    17881 tcaatttttt caagctattt ccaagggttg taaaatcgtc cctgattctg caagataagt
    17941 agtaaactaa ctactaaaaa caaggttgcc aagagcaagg taatatagtc tccttttttc
    18001 aaggcctgat aactatacca tgtgcgtttt ttctctttcc caaagcggcg aagctccatg
    18061 gcagtcgcaa tggtatcaat gcgttctagc gagctaaaaa tcaagggcgt aataatgagc
    18121 agattgcctt tgattcgttg cataagagaa gctttcttgg ataattccat cccacgcgcc
    18181 tcctgagaca tcttgatagt aaagaattct tcctgcaaat ctggaatata gcgcaaggtc
    18241 aggctgacag aataagcaat cttatagggc acaccaattt gatttaaact ggaagcaaac
    18301 tgactaggat gggttgtcat caaaaagata atagccagag gaatggtgca aagatactta
    18361 atggccaaat ttagcagata aaagagctcc tggctggtta gagtgtagac accgattccc
    18421 tgccaaatca cacttctctc tccataaagt ccaaccccat actcgggaga aaagagatag
    18481 accatcaaaa cgtttaaaac ggcaaatacc gtcgcaaaaa cggctacaaa ggaaacatct
    18541 ttaaagcgaa tttctgataa atagaggaga aagactgaaa agatggcaat cagcaagagc
    18601 attctggtat catagctaat catggccgcc aatgatacca gaatgaaaaa gagaagtttc
    18661 ccagctcctg acaagcgatg aatcacagta tctctatgct ggtaaccgat taatttagct
    18721 tgcatccctc tctcctttct ttgtaaaatg ccgttaaatc cagtggatcc acatctagtt
    18781 tcttagccaa gttaaagatg gaggtttctt ttagattggc ttttactaac agctcaggat
    18841 cgctcaacag actggctgga acagtatcgg caatcaattc tccatccacc atgacaagga
    18901 cccggtctga ataatccagc atcaattgca tatcatgggt aatcatgaca atggtatgcc
    18961 ctttttgatg taactcttcg agaaattcca taatctcagt atagttcttc tgatcttgac
    19021 ctgcagtcgg ttcatctagg agaataattt cagctcctaa gaccaaaatt gaagcaatgg
    19081 tgacacgttt tttctgacca aatgacaggg cagaaatagg ccaattacgg aattcataaa
    19141 gtccacagat tttcaaggtt tcatagactc tcgtttcaat ttccttctca tccacacctc
    19201 gcaaacggag ccctagagcc acctcatcaa aaatcatatt ggttgaaatc atttgattag
    19261 gattttgtag cacatagcct actcgttccg cccgctctgc aacagaatcg ccttttatat
    19321 cctgtttttc ccaaagatag cgtccttccg tctgaataaa gctacttata gccttggcta
    19381 gagttgattt ccctgctcca ttttttccga caatagcaat cttttcaccc tttttaatat
    19441 ctaaatgtag ggattttaaa atcggtctat catcataaga gaaagacacg tcctctaatt
    19501 taaagagtga ctgcaattct ggagtttctt ttgccagttc attctgcagc tgaacctgac
    19561 cttttgagat agacatgtta tccagattcg ctaactgttc ttccttgact aagtccacac
    19621 ctaattgacg gagagtcgtt agataaaggg gttctcgaat tccattttga gtcaataaat
    19681 cagtcgcaag caactggtca gggctcccat taaaaaggat acgaccatcg cttatcaaga
    19741 caatccgatc cacagggcga tgcagaacat cctccaaacg gtgctcgata atcagagtcg
    19801 tcgtcccctc ttccttatga atctggtcaa tcaattcgat aatatcctga cctgacttgg
    19861 gatctagatt ggcgagtggc tcatcaaaca agagaatcgg actttcatca atcaagacac
    19921 cagccagact gactcgctgc ttttgtccac ctgacaaatc ctgaggacgc tgatccagta
    19981 aaggaagaag gtccagcttt tcagcccatt tataaacacg acctttcatc tcatctaggg
    20041 ctgtcacatc attttccaga gcaaacgcca aatcttctgc cacagacaag ccaataaact
    20101 gcccatctgt atcctgcaaa actgtgctaa ccagatgaga cttatcatag atgctcatat
    20161 caaaggctac ttgacccttt atcaaaaatt ctccatatgt ctgacccttg taaatattgg
    20221 gaataatccc attcaaacac tgacccaagg tagatttacc tgacccagat ggtccaacaa
    20281 ttaagacttt ctctcccttg taaatggtca agtctatccc ttgcaaggtc ggttcttgtt
    20341 gtgtttcata ccggaaagag aaatccttcc actcaattat agcttctttc atcttactct
    20401 cttcattcgc ttcttagact tctattttat cataaatcaa gcccttcttg cagtctcttc
    20461 tcttaaaatc ttagcgccaa aaagattcct atcctagctt acttgcctaa ctaatctata
    20521 aacatcgaaa aagactagtt gcccagcctt ccccatcatt ttatactctt cgaaaatctc
    20581 ttcaaaccac gtcagcttc
//
LOCUS       DBEJHE010000032        19641 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC4 isolate 671759
            SAMN38261586-rid24793303.denovo.32, whole genome shotgun sequence.
ACCESSION   DBEJHE010000032 DBEJHE010000000
VERSION     DBEJHE010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261586
            Sequence Read Archive: SRR26833752
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 19641)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19641)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576136.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576136.1
            Genome Coverage       :: 109x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 19:48:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,067
            CDSs (total)                      :: 2,029
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 131
            CDSs (without protein)            :: 131
            Pseudo Genes (ambiguous residues) :: 0 of 131
            Pseudo Genes (frameshifted)       :: 64 of 131
            Pseudo Genes (incomplete)         :: 59 of 131
            Pseudo Genes (internal stop)      :: 46 of 131
            Pseudo Genes (multiple problems)  :: 32 of 131
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19641
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261586-rid24793303.denovo.32"
                     /strain="GPSC4"
                     /isolate="671759"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(<1..1713)
                     /locus_tag="ACL3EZ_001643"
     CDS             complement(<1..1713)
                     /locus_tag="ACL3EZ_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="HGR0393181.1"
                     /translation="MTRKVPNIEQMSQIECGLCCCLSILHFYKSKETLLDLRRDIEKG
                     RDGYSIGDLKQLLNKRNFDTGSYQVKDVNKISELPLPLIAFWDNQHYVVIYKVKKNKV
                     YIMDPSKGYINYEFKEFSKHFSNIVLLSFPNENYQSLKSQFPSPWIRVFSSFSKVKGR
                     LILTLLFSIISYLIILSVPVMTSKFINSALGNTFSFQTSFLILFSLLCLYLISILARS
                     MGILFSNIFFSRDIESFTFKHLLKLPYSFFELRAKGDILYRISSLSGFRELFTNQVVG
                     GVVDIGTILSVVIYMFLSSKTLSIIALILSLINFLFLFSTRKIMYDTVNRELQEQSLI
                     YSVETEALNTISSIKISGLEDEIYENWSKYLKNVLTKYKKRSIVHILYNSATNVFQLF
                     APIIILIFGLDNVLNGKILLGEVVAFQTMASILFSSEISIFNAYTQYILAAGYLNRVN
                     DIWLENEENVENGLKKCSLEGRIDIKDLSFSYSKDSAPVIENLNLTIEPGQRIALVGQ
                     SGSGKSTLSKILSGLYKIDTGKILFDGVNINQIDKKILSQNLGVVPQDSFLLNRSILD
                     NITLK"
     gene            complement(1706..2254)
                     /locus_tag="ACL3EZ_001644"
     CDS             complement(1706..2254)
                     /locus_tag="ACL3EZ_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000059560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0031179 - peptide modification [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lanthionine synthetase LanC family protein"
                     /protein_id="HGR0393182.1"
                     /translation="MSLSYYYEINPSTDILKCIEELLYKEDKCFNNILKNWKDIRRNH
                     NDSFPNFWCYGAPGILLARKEIFDKTNIGNNDLSIIKNVLTNVEKIRELNLCHGSVGT
                     ISCLDAILKDEENLLIKESIDFYFDNVVSQVIKPELSTDLNTMNTFSFMLGVSGVVYE
                     ISRKQDDRLLNVLLLELRGHDD"
     gene            complement(2335..2397)
                     /locus_tag="ACL3EZ_001645"
     CDS             complement(2335..2397)
                     /locus_tag="ACL3EZ_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_128650800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SHP2/SHP3 family peptide pheromone"
                     /protein_id="HGR0393183.1"
                     /translation="MKKISKFLPILVLVMDIIII"
     gene            2477..3331
                     /locus_tag="ACL3EZ_001646"
     CDS             2477..3331
                     /locus_tag="ACL3EZ_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HGR0393184.1"
                     /translation="MKSKLGITLRKVRKGKQISLCSVADEHLSKSQISRFERGESEIS
                     CIRLINILDKLHITLDEFLVLHNDDYTSSESFANLVQYIRKQYSSQSINNIACLLSDT
                     SDYTLNSFEKTMVKSILHTMDSNIIPSDEELLHLTDYLFKVEKWGYYEIILLGNCVRT
                     INYNSYFLLTKEMLNNYIYSSLNKTNKQIVSQLAINCFILSIDKEEFSNCSYLISKIK
                     TLLDNELNFYEQTVFLYATGYFEFKRCQSTSGIEKMKQAIQVFDILGEDKLKLHYTDH
                     FNKLVNKK"
     gene            complement(3376..5241)
                     /locus_tag="ACL3EZ_001647"
     CDS             complement(3376..5241)
                     /locus_tag="ACL3EZ_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000261806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAG1250 family conjugative relaxase"
                     /protein_id="HGR0393185.1"
                     /translation="MVVTKHFATHGKKYRRRLIKYILNPDKTDNLKLVSDFGMSNYLD
                     FPSHAEMVEMYNVNFSNNDKLYESRNDRQEKHQQTIHAHYLIQSFSPEDNLTPEEINR
                     IGYEIMMELTGGRFKFIVATHTDKDHVHNHILINAIDRNSDKKLIWNYALERNLRMIS
                     DRISKVTGAKIIEKRYSYRDYKKYRESSHKFELKQRLYFLLQQSKSFDDFLEKAKQLH
                     VQIDFSQKHSRFLMTDRTMIKPIRGRQLSKRDLYDEDFFKIYFAKQEIESRLKFLLKS
                     VYSLEELHVKAKELNLTIELKQKNVMFTLEEDGKKISLSHKKISDKKLYDVQFFNRYF
                     EDREVRDIQALENLQEDFQTFREEQHKEKVSAEEIEEAFKKYKEKRDAIHEFEIELTD
                     NQIEKLVDDGVYIQVSFGIKQSGLIFIPNYQLDIFEEDNHKKYKVYIRETSSYFVYNK
                     ENMDNNCFIKGRTLIRQLSNDSQKLPYRRPTLKSLKEKISEINLMIELSNTNKQYQEI
                     KDELVLEIAEIDMQLEETQEKIATLNKMAEVLINLKSEDHETRKLAKYDFDQMNMTES
                     IMLDRLNTDILKLQQELGNEINKYEEIARRLDLFVKIINTNKFTVLKFHENALLE"
     gene            complement(5228..5593)
                     /gene="mobC"
                     /locus_tag="ACL3EZ_001648"
     CDS             complement(5228..5593)
                     /gene="mobC"
                     /locus_tag="ACL3EZ_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000263054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HGR0393186.1"
                     /translation="MVYRYRTNLKKVFLTDSELHQLNERIAKSNCQNFSVYARKVLLN
                     PNMSFVTINTDTYEQLVFELRRIGNNINQIARAINQSHLISQNQLQELSKGVGELIKE
                     VDKEFQVEVKRLKEFHGSY"
     gene            complement(5603..5962)
                     /locus_tag="ACL3EZ_001649"
     CDS             complement(5603..5962)
                     /locus_tag="ACL3EZ_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018379612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAG1252 family conjugative relaxosome accessory
                     protein"
                     /protein_id="HGR0393187.1"
                     /translation="MSEQYRDIRKEVNLTADELKQIEKMMEVDNYRHFSPFVRDKILM
                     TDDKQLAAKEWFSLWQSQKFEQISRDVHLVLIIARENHQVTQEHVSILLTCVQELIAE
                     VNQVQSLSRGFREKYMR"
     gene            complement(6781..7158)
                     /locus_tag="ACL3EZ_001650"
     CDS             complement(6781..7158)
                     /locus_tag="ACL3EZ_001650"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0393188.1"
                     /translation="MGQKVVAMLDFLLAYSDYSKDFRPLIIDQPEDNLDNRYICRHLV
                     QQFRDVKAQRQIILATHNATIVTNSMTDQVVIMESDGVNGWIESQGYVSEKYIKNHII
                     NQLEGGKDSFKHKMSIYETALSE"
     gene            complement(7161..7937)
                     /locus_tag="ACL3EZ_001651"
     CDS             complement(7161..7937)
                     /locus_tag="ACL3EZ_001651"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0393189.1"
                     /translation="MRGFNNKIKSVYQELTNSKEKFGSFHKTLIHLHTPVSYDYKLFS
                     NWTATKYRKITEDELYDIFFENKKIKVDKTIFFSNFDKVVFSSSKEYISFLMLAEAII
                     KNGIEIVVVTDHNTTKGIKKLQMAVSIIMKNYPIYDIHPHILHGVEISAADKLHIVCI
                     YDYEQESWVNQWLSENIISEKDGSYQHSLTIMKDFNNQKIVNYIAHFNSYDILKKGSH
                     LSGAYKRKIFSKENTRFWSLILTRKNLRNNLIFSIKKLVY"
     gene            complement(7965..8726)
                     /gene="pezT"
                     /locus_tag="ACL3EZ_001652"
     CDS             complement(7965..8726)
                     /gene="pezT"
                     /locus_tag="ACL3EZ_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system toxin PezT"
                     /protein_id="HGR0393190.1"
                     /translation="MEIQDYTDSEFKHALARNLRSLTRGKKSSKQPIAILLGGQSGAG
                     KTTIHRIKQKEFQGNIVIIDGDSFRSQHPHYLELQQEYGKDSVEYTKDFAGKMVESLV
                     TKLSSLRYNLLIEGTLRTVDVPKKTAQLLKNKGYEVQLALIATKPELSYLSTLIRYEE
                     LYIINPNQARATPKEHHDFIVNHLVDNTRQLEELAIFESIQIYQRDRSCVYDSKENTT
                     SAADVLQELLFGEWSQVEKEMLQVGEKRLNELLEK"
     gene            complement(8726..9202)
                     /gene="pezA"
                     /locus_tag="ACL3EZ_001653"
     CDS             complement(8726..9202)
                     /gene="pezA"
                     /locus_tag="ACL3EZ_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003042293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system antitoxin PezA"
                     /protein_id="HGR0393191.1"
                     /translation="MIGKNIKSLRKTHDLTQDDFSRIVGISRNSLSRYENGTSSVSTE
                     LIDIICQKFNVSYVDIVGEDKMLNPVEDYELTLKIEIVKERGANLLSRLYRYQDSQGI
                     SIDDESNPWILMSDDLSDLIHTNIYLVETFDEIERYSGYLDGIERMLEISEKRMVA"
     gene            complement(9647..10102)
                     /locus_tag="ACL3EZ_001654"
     CDS             complement(9647..10102)
                     /locus_tag="ACL3EZ_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0393192.1"
                     /translation="MGAARDFLELINHKGLPLFNPLVGDSHVNNRQEYDNTGSENLQP
                     EKWNETAKQLYNAIMWLIILWNAKPDTPLFNFKDEVIKYKTYEPFESSIKRVNTTIKN
                     GSKGKTLTEMINGYRADNDIRDEICNFNILKNKIRDMKDQQGNTMESYF"
     gene            complement(10377..12116)
                     /locus_tag="ACL3EZ_001655"
     CDS             complement(10377..12116)
                     /locus_tag="ACL3EZ_001655"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 13 protein"
                     /protein_id="HGR0393193.1"
                     /translation="MELSAIYHRPESEYAYLYKDKKLHIRIRTKKGDIESINLHYGDP
                     FIFMEEFYQDTKEMVKITSGTLFDHWQVEVSVDFARIQYLFELRDTEGQNILYGDKGC
                     VENSLENLHAIGNGFKLPYLHEIDACKVPDWVSNTVWYQIFPERFANGNALLNPEGTL
                     DWDSSVTPKSDDFFGGDLQGIIDHMDYLQDLGITGLYLCPIFESTSNHKYNTTDYFEI
                     DRHFGDKETFRELVDQAHHRGMKVMLDAVFNHIGSQSLQWKNVVKNGEQSAYKDWFHI
                     QQFPVTTEKLVNKRDLPYHVFGFEDYMPKLNTANPEVKNYLLKVATYWIEEFNIDAWR
                     LDVANEIDHQFWKDFRKAVLAKNPDLYILGEVWHTSQPWLNGDEFHAVMNYPLSDSIK
                     DYFLRGIKKTDQFIDEINGESMYYKQQISEVMFNLLDSHDTERILWTANEDVQLVKSA
                     LAFLFLQKGTPCIYYGTELALTGGPDPDCRRCMPWERVSSDNDMLNFMKRLIKIWKYA
                     SVIISHGKYSLQEIKSDLVALEWKYEGRILKAIFNQSTEDYLLEKEAVALASNCQELE
                     NQLVISPDGFVIF"
     gene            complement(12279..13163)
                     /locus_tag="ACL3EZ_001656"
     CDS             complement(12279..13163)
                     /locus_tag="ACL3EZ_001656"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HGR0393194.1"
                     /translation="MKKAMVIINPTSGGEKALDYKEKLENKAKEYFEYVETKITEKAL
                     DATHFAEEASREQYDAVVVFGGDGTVNEVISGIDERDYIPKLGIIPGGTGNLITKLLE
                     INQDIDGAIDELDFDLTNKIDIGKANDNYFGYIFSIGSLPEAIHNVEIEDKTKFGILT
                     YAVNTMKSVMTDQVFNIKVETENGNYVGEASHVLVLLTNYFADKKIFEENKDGYANIL
                     ILKDASIFSKLSVIPDLLKGDVVANDNIEYIKARNIKISSDSELESDVDGDKSDNLPV
                     EIKVLAQRVEVFSKPKED"
     gene            complement(13275..14129)
                     /locus_tag="ACL3EZ_001657"
     CDS             complement(13275..14129)
                     /locus_tag="ACL3EZ_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HGR0393195.1"
                     /translation="MLGAIIGDIVGSVYEWNNIKTKDFPLFRKDCFFTDDTVMTCAVA
                     EAIMNGGQKDDFIDAMKKYGRMYPNADYGARFNAWLNSDNREPYNSFGNGSAMRISPC
                     AWIMDCGFYAKTGIWPSSRGLTSLSAEVTHNHPEGVKGAMATADAIFLCRFYFGGYCR
                     EYEQSINDNPTECKRRIKDYIEKEYDYNLSQTLDEIRPNYRFNETCQETVPQAIIAFL
                     ESRDFEDAIRNAISLGGDSDTLAAITCSIAEAAYGIPDWIKDKDYSYLDEPLKDVVRR
                     WENRIKAY"
     gene            complement(14187..14945)
                     /locus_tag="ACL3EZ_001658"
     CDS             complement(14187..14945)
                     /locus_tag="ACL3EZ_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HGR0393196.1"
                     /translation="MVVYIRQSKLLSEVSINKYNAQVGAYLQGEEVILYQSFSEIKEL
                     TSEDIDVDYIMETRALLKMMGLNVPVYDYPIELKEFYGRKIYAGILGEIVNIPDNWGK
                     FIKPKAGSKVFTGRVVNGTHDLIGIGLPFDYPIWISEVVEFIAEWRCFVLDGRVLDVR
                     PYTGDYHAQFDASVIDEAISCWKDAPIAYGLDIGVTRDGRTLVVEVNDGYALGNYGLS
                     PLKSINFHRARWKEMVKPYFEKNEIFKIQQDVIF"
     gene            complement(15007..15195)
                     /locus_tag="ACL3EZ_001659"
     CDS             complement(15007..15195)
                     /locus_tag="ACL3EZ_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HGR0393197.1"
                     /translation="MATDKNRIMISLDDKNLEKLENLVEDARDRRGMRLTKSQVIELL
                     LNTVDYFDDIMGAIYSKK"
     gene            complement(15517..16083)
                     /locus_tag="ACL3EZ_001660"
     CDS             complement(15517..16083)
                     /locus_tag="ACL3EZ_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0393198.1"
                     /translation="MVILELYQNDYSKDLVAFDSIEDGKAFVAQIPGYTLETEDGFEV
                     EYFNPKNIPDYMEIIFNGNIVPLSKFMFDPEENVNIIWKEISNLSLKNDRVIEGYSKI
                     DAYVVNNHEVKAYVETRETNYRKAKDFLESRGYEIDRSFFGSEDGEAILYRKKGIEVW
                     HFLCHLDPMFVEIEDVEGYVKEEVGEIQ"
     gene            complement(16351..18030)
                     /locus_tag="ACL3EZ_001661"
     CDS             complement(16351..18030)
                     /locus_tag="ACL3EZ_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HGR0393199.1"
                     /translation="MSKEKIKVYLYTRVSTSIQIEGYSLEAQKSRMKAFAIYNDYEIV
                     GEYEDAGKSGKSIEGRIQFNRMMEDIKSGKDGVSFVLVFKLSRFARNAADVLSTLQIM
                     QDYGVNLICVEDGIDSSKDAGKLMISVLSAVAEIERENIRIQTMEGCIQKAREGKWNG
                     GFAPYGYKLEDGKLFINEEEAVAIRTIFDQYVNTTIGANGISKYLENHGIRKIPRQNG
                     KNPLFDAGLIRKILKNPVYNGKIAFGRRTLEKVHGTRNEYKQVEQDEYLISEGIHEAI
                     VSDEVWQAAQVKLKSQAKKYEHVNKGKDTRTHLLSGIVKCPICGVGMFGNKCIKKKKD
                     GTKYKDFYYYGCKHRQMIRGHKCTFSKQIREELLDDAVAEVIVKIVSNPKFASMMQEK
                     INMKVDTSEIEKEIDNYQKELRKSHSTKFKLIEEIDNLDVEDKHYKRRKQDLDDRLYR
                     MYDKIDELESSLIDAKAKKQTIEAEKLTGDNIYKVLIYFDKLYKVMNDVERRQLISAL
                     ISEIQVYEERQSNGQWLKSITFKLPIIEENLNIGLDNDEQVECVSLLEKRS"
     gene            complement(18122..18283)
                     /locus_tag="ACL3EZ_001662"
     CDS             complement(18122..18283)
                     /locus_tag="ACL3EZ_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0393200.1"
                     /translation="MDNDWNGLADLIANLIAKYAGALDLDNLPDPTPAKNQEMKNSFD
                     MAKTQIETD"
     gene            complement(18967..>19641)
                     /locus_tag="ACL3EZ_001663"
     CDS             complement(18967..>19641)
                     /locus_tag="ACL3EZ_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000224688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage replisome organizer N-terminal
                     domain-containing protein"
                     /protein_id="HGR0393201.1"
                     /translation="DKRIKRLRRISGGDTYTIIYLKLLLLSLKDEGKLYYDGVESDFI
                     KELALTIDETDDDVMVTVNYLINQGLLEVVTENDEYYLTEIPNLIGSETAWAEKKRRY
                     RQNKQRTLSLMSPTHVRQEIEIEKDIEIDKEREGEIDKKSTPIFYGEFKNVRLSKEEY
                     KNLKEKLNSHTDIMINKLSRYMESSGKTYQNHYVTILKWYEEDKDKLRQKGLNKKMNY
                     DVGESL"
BASE COUNT         5995 a         3858 c         2677 g         7111 t
ORIGIN      
        1 ctttaaagtt atattatcaa gaatacttcg gttcaataaa aatgaatcct gtggaactac
       61 tcctaaattt tgacttaata tttttttatc tatttgatta atatttacac catcaaataa
      121 aatttttcct gtatcaatct tatataatcc tgatagtatt tttgataacg tactttttcc
      181 tgaccccgat tgaccgacta gtgcaattct ctgtcctggc tcaatagtca aatttaaatt
      241 ttctattaca ggagctgagt ctttggaata agagaaagat aggtccttaa tatctattct
      301 accttctaaa gaacactttt taagaccatt ttcaacattc tcttcatttt caagccagat
      361 atcatttact ctatttaagt atcctgctgc caaaatatac tgcgtataag cattaaatat
      421 tgagatttct gaactaaata aaattgatgc catggtttga aatgcgacaa cctcacccaa
      481 taaaattttt ccatttaaaa cattatcaag tccaaaaatc aatataatta taggagcgaa
      541 caattgaaat acattagtag ctgaattgta taaaatatgc acaatacttc gttttttata
      601 ctttgtcaat acgtttttta aatacttaga ccagttttca tatatttcat cttctaatcc
      661 cgatattttt attgaagaaa tagtatttaa tgcttctgtt tctactgagt aaatcaatga
      721 ttgttcttgt aattctctat taaccgtatc atacattatt tttctagtac taaacagaaa
      781 caaaaaattg attaaactca atataagagc tataattgat aatgtttttg aactaagaaa
      841 catatatatt acaacactta gaatagtccc gatatctact actcccccaa caacttggtt
      901 agtaaatagc tccctaaaac cactaagact agaaattctg tataaaatat ctccttttgc
      961 cctgagttca aaaaaactat atggtagttt aagcaaatgc ttaaatgtaa aactttcaat
     1021 atctctacta aaaaatatat tagaaaatag aattcccata ctcctagcca agatagaaat
     1081 aagatacaaa caaagtagag aaaataaaat taaaaacgag gtttgaaaag aaaatgtatt
     1141 ccctaatgca gaattaataa actttgaagt cattactggt acggaaagta ttattaagta
     1201 acttattatt gaaaatagta acgtcaaaat caatcgacct tttacctttg aaaaactaga
     1261 gaatactctt atccatggag aaggaaactg cgacttcaaa gattgataat tttcgttagg
     1321 aaatgatagc agtactatat tactaaaatg ttttgaaaac tccttaaact cataatttat
     1381 atatccttta gaaggatcca ttatatagac cttattcttt tttactttgt aaataactac
     1441 ataatgttga ttatcccaga atgctattaa tggtaacgga agttcactaa ttttatttac
     1501 atctttaact tgatatgagc cagtatcaaa atttcgttta ttcaataact gtttcaagtc
     1561 acctatacta taaccatctc tccctttttc tatatcacgt cttaaatcta gtaatgtctc
     1621 tttgctttta tagaaatgta gtatggacaa gcagcaacat aaaccacatt ctatttgaga
     1681 catttgctca atattaggta cttttctagt catcatgtcc tcttaactcc agtaataaaa
     1741 cattaagtaa tctatcatct tgttttcgag atatttcata gacaactcca gatactccta
     1801 gcataaaaga aaatgtattc atagtattca aatccgtact taattctggt ttgatgacct
     1861 gagaaacgac attatcaaaa taaaaatcta tagattcttt tattaatagg ttttcttcat
     1921 ctttcaatat tgcatcaaga caactgatag tacctacaga accgtgacat aaattcaatt
     1981 ctcttatttt ttctacatta gttaatacat ttttaattat tgataaatca ttattcccaa
     2041 tattagtttt atcgaaaatt tcttttctag ctaataaaat gcccggagct ccataacacc
     2101 aaaaattagg aaaggaatca ttatgatttc ttcttatgtc tttccaattt tttaatatat
     2161 tattgaaaca tttatcttct ttatatagta attcctctat acattttaat atatctgtac
     2221 taggattaat ttcataataa tatgataatg acattgctac tccagaataa ccgtgtgcta
     2281 aacctgttac tgttatatta tctaattgtg aaatacaata attaatacac ttttttaaat
     2341 gatgataata tccatcacca aaaccaaaat cggtaaaaat tttgaaattt tcttcatact
     2401 tggacttcct ttccgttttt atttattgta caataaataa aaacggattt aatttttgtt
     2461 gggaaaatgg gaaattatga aatcaaaact tggcatcaca cttagaaaag ttcgtaaagg
     2521 aaaacaaatt agtctatgct ctgtagcaga tgaacatctt tcaaaatcac aaatatctcg
     2581 ttttgaacgt ggggagtcag agatatcttg tattcgacta atcaatattt tagacaaatt
     2641 acatattact ttggatgagt tccttgtttt acacaatgac gactatacca gttccgaatc
     2701 atttgctaat ctagtacagt acattcgtaa gcaatattca tcacaaagta tcaataatat
     2761 agcatgtcta ctttctgata cttctgatta cactctaaat tcttttgaga aaacaatggt
     2821 aaaatctatt ttacacacaa tggattcgaa catcattcca tcagatgaag agcttcttca
     2881 tctgacagac tatcttttca aagttgaaaa atggggctat tatgaaatca ttttattagg
     2941 taactgtgta cgcacaatta actacaactc ctacttctta ttaactaaag agatgttaaa
     3001 taactatatt tactcatctc tgaataaaac taataagcag attgtctctc agcttgctat
     3061 taattgcttc attctaagca ttgataagga agaattttct aattgctcct atttaattag
     3121 taagataaag acattgttgg acaatgaact aaacttttat gaacaaacag tttttctcta
     3181 tgcaactggt tactttgaat ttaaacgttg ccaatcaacc agtggaattg aaaaaatgaa
     3241 acaagccata caagtcttcg atattttagg agaagataag ttaaaattac actatactga
     3301 ccattttaat aaactagtaa ataaaaaata aatgaaatta ttctctatct tttaactaat
     3361 tagtcgtaaa taatattatt ctagtaaggc attctcgtga aattttagaa ctgtaaattt
     3421 attggtatta ataattttca caaacaaatc caatcttcta gctatctcct catatttatt
     3481 aatttcatta ccaagttcct gttgtaattt taaaatatcc gtattgagtc gatctaacat
     3541 tattgattcc gtcatgttca tttggtcaaa atcatactta gctaattttc tagtctcatg
     3601 atcttcactc ttcaaattga taaggacttc cgccatcttg tttaaggtgg cgattttttc
     3661 ttgggtttct tctagctgca tatcaatctc tgcaatttct aatacaagct catctttgat
     3721 ttcttggtat tgtttgttcg tgttagatag ttcaatcata agattaattt cagaaatctt
     3781 ctctttaaga ctttttaaag ttggtcgtct ataggggagt ttttggctat cgttgctcaa
     3841 ttgtctgatt aaggtcctac ccttgatgaa acaattatta tccatgtttt ctttattata
     3901 gacaaagtaa gaagacgttt ctcgaatgta gactttatat tttttatgat tgtcttcctc
     3961 aaaaatatct agctggtagt taggaataaa gatgagtcca ctctgtttga taccaaacga
     4021 aacctgtata tagacaccat catcaaccaa cttctctatc tgattatccg taagttcaat
     4081 ctcaaactca tggatagcat ctcgtttttc cttgtatttc ttgaaggctt cctcgatttc
     4141 ttcagcggag actttctcct tatgctgctc ctctcgaaaa gtctgaaaat cttcctgaag
     4201 attttctaat gcttgaatat ctctaacttc tctatcttca aaataacgat taaaaaattg
     4261 aacatcgtac aatttcttat cgctaatttt tttatgactc aggcttatct ttttgccatc
     4321 ttcttctagg gtaaacatca catttttctg ttttaactcg atggttagat tcaactcttt
     4381 agcctttaca tgcaattctt ctaatgaata aacagacttt agtaaaaatt ttaaacgact
     4441 ttcaatctct tgtttggcaa aatatatttt aaaaaagtct tcatcatata aatctcgttt
     4501 gctgagttgg cgtcctcgaa ttggttttat catcgttcta tctgtcatca aaaaacggct
     4561 atgcttttga ctaaaatcaa tctgaacatg caactgcttt gctttctcta aaaaatcatc
     4621 aaacgattta gattgctgta gcaaaaaata aagacgttgt ttcaattcaa acttatgact
     4681 agattcccta tattttttat aatctcgata ggaataacgt ttctcaataa tttttgcacc
     4741 agtcacttta gaaatacggt ctgaaatcat acggaggttt cgttccaagg catagttcca
     4801 tatcaacttt ttatctgaat tgcggtcaat agcgttgatt aggatgtgat tatgaacatg
     4861 atctttgtct gtgtgagttg ctacgataaa cttaaaacga cctcctgtca attccatcat
     4921 gatctcataa ccaatgcggt taatttcttc aggtgtcaga ttatcttcag gagaaaatga
     4981 ttgaatgagg taatgagcat gaatagtttg ttggtgtttt tcttgtcggt cgtttctgga
     5041 ttcgtacaac ttgtcattat tgctgaagtt gacattgtac atctctacca tttctgcatg
     5101 actagggaag tccaagtaat tgctcatgcc aaaatcagat accaatttca aattgtccgt
     5161 tttatcaggg ttgagaatat acttaattaa acgcctacga tatttttttc cgtgcgtcgc
     5221 aaagtgttta gtaactacca tgaaactcct tcagtctttt cacctccact tgaaattctt
     5281 tgtccacttc cttaattaac tctccgactc ctttactcaa ttcttgtaat tggttctgag
     5341 aaatcagatg gctttgatta atcgcacgcg caatttgatt gatgttattt ccaatcctcc
     5401 tcaattcaaa cactaactgt tcataagtat cagtgttaat cgtgacaaat gacatattgg
     5461 gattaagcaa aacttttctg gcatagactg agaaattttg acaattgctc ttagcaatcc
     5521 gttcattcaa ttggtgtaat tctgaatctg ttagaaatac ttttttgaga ttggtacgat
     5581 aacgataaac catagtagcc tcctatctca tgtatttttc acgaaaccca cgactgagtg
     5641 actgtacttg attgacttcc gcaatcaatt cttgaacgca ggtcaataag attgacacgt
     5701 gttcttgagt cacttggtga ttctctcttg cgataatcaa aaccaaatgc acatctcgac
     5761 tgatctgttc aaacttttga gactgccaaa gggaaaacca ttctttggca gctaactgtt
     5821 tgtcatcagt catcaaaatt ttatccctga cgaatggtga aaagtgacga taattatcaa
     5881 cctccatcat tttttcaatc tgttttagct catctgcggt tagatttacc tcttttcgaa
     5941 tgtcacggta ctgttcagac atctcttttc ctcactttca tcctttctcg ggtaaacccc
     6001 gaccccgtgt gtcatacggg aaatttctta aagtccttgt tcggtctttg cgagctcaag
     6061 cattgtggtt acaataccca aaaaatcata tcgccagcta accaaaacct tccagttttg
     6121 acagccaacg ataagataac ttggtggctt cgcccccaaa cccccaggta aaattcttag
     6181 ttggattttt aaaagttgag aaaagtatag cagaagaaat ttggggaagt tatcacaaat
     6241 caagtaggga ctaatctcta acaccactgc atgtaccgtc ctatatttat aatcagctcc
     6301 catcgtttac attttcaggt cactgtcttt tcataccagg aattagaatt gacaaattta
     6361 attagagagg tattcattta attgttcact tcttcgctcc atttccatta cagaaatttc
     6421 ttcaatacta tgtgttcagc tgactcccat gattcgttgt actacgtcct aaacgctcac
     6481 ggaataagcc gtacatcttt cctagtttac tctcgtaatt tacgtatata ggttacgaca
     6541 cctatttgga ttttagagtt cctcatccgc tatatatggc ttcaagtcac gattctgttt
     6601 gtagaacctt gatttcgcta attccttcct atccccccta cctcacgata ttcaggctta
     6661 ggagtcgcta ttggtttcat ctgcagcaaa tatccacaga ggacttggac ctcagatgca
     6721 cactatgcct gtcggacaaa gaaaaaagta ggctaaattt ctaacctact ttttctgact
     6781 ctactctgat aaagccgtct catatataga cattttatgc ttgaaggaat cttttcctcc
     6841 ctctaattga ttgatgatat gattttttat atatttttca ctaacatatc cctgtgattc
     6901 aatccatccg ttaactccat ctgactccat aataacaact tgatctgtca tagaatttgt
     6961 tacaattgta gcattatgtg ttgctaaaat aatttgacgt tgagctttca catctctaaa
     7021 ctgctgaact aaatgcctgc aaatataacg attgtctaga ttgtcttcag gctgatcaat
     7081 aatcaatggt ctgaagtctt tagaataatc actatatgct aataaaaaat caagcatggc
     7141 tacaactttt tgtcccaaac ttaatacacc aacttcttta tagagaatat caagttgttg
     7201 cgaagattct ttcgagttaa tattaaactc caaaatcgtg tattttcttt agaaaaaatt
     7261 tttcgtttat atgcacctga taagtgagaa ccttttttca aaatgtcata actattgaaa
     7321 tgagcaatat agttaactat tttttgatta ttgaaatcct tcattatagt cagtgaatgt
     7381 tgataacttc catctttctc acttataata ttttcactta accattgatt aacccatgat
     7441 tcttgttcat aatcatatat acatacaata tgcaatttat ctgctgcact aatttctact
     7501 ccatgtaaaa tatgaggatg tatatcataa atcggataat ttttcattat gattgagact
     7561 gccatttgta actttttaat acctttggta gtattatgat cagttactac aactatttct
     7621 attccatttt ttatgattgc ctctgctaac ataagaaaac taatatattc ttttgaacta
     7681 gaaaaaacaa ccttatcaaa attactaaaa aaaattgtct tatcaacttt tattttctta
     7741 ttttcaaaaa atatatcata tagttcatct tcagtaattt ttctatattt cgttgcagtc
     7801 caattagaaa atagcttgta atcataagaa acaggtgtat gcaaatgaat taaagtcttg
     7861 tgaaagctac cgaatttctc tttggaattt gttagttctt gataaacaga ctttatcttg
     7921 ttattaaacc ctctcatttc tattctccta aaaatatcaa ttgtttattt ttcaagtaat
     7981 tcattaagtc tcttttcccc cacctgcaac atctccttct ctacctgact ccactcccca
     8041 aagagtaact cttgaagaac atctgctgct gaagttgtat tttcttttga atcatataca
     8101 caacttctat ctcgttggta aatttgaatg ctttcaaaga tagccagttc ttccaattgt
     8161 cgtgtattat caactagatg atttacaatg aaatcatgat gttcttttgg agttgcgcgt
     8221 gcttgatttg gattgataat gtacagttct tcataacgga taagagtact tagatacgac
     8281 aattcaggct ttgtcgcaat taaggccaat tgtacttcat atcccttatt tttcaagagt
     8341 tgtgctgttt tctttggaac atcaactgtt cgtaaagttc cctcgatcaa aagattgtat
     8401 ctcaaactac tcaattttgt tactaaagac tctaccattt ttcctgcaaa atctttggta
     8461 tattctacac tgtctttgcc atattcttgc tgcagttcta aatagtgtgg atgctgagaa
     8521 cgaaaactat caccatctat gataacaata tttccttgaa attctttctg tttaatacga
     8581 tgaattgtag tcttaccggc accactttgc cctccaagca aaatcgctat aggttgctta
     8641 ctggactttt ttcctcttgt cagtgaacga agattccttg ctaaagcatg tttgaattca
     8701 ctatcagtat aatcttggat ttccattaag ctaccatccg cttttcagat atctctaaca
     8761 tacgttcaat tccatccaaa tagccactat atctctctat ttcatcaaaa gtttctacta
     8821 aatagatatt cgtatgaatc aagtcagata gatcatcact cattaaaatc caaggattag
     8881 attcatcatc aatgctaatt ccctgactat cttgataacg atagagtcga gataatagat
     8941 tagcacctct ttctttcaca atttcaattt tcaaagtcaa ttcataatct tcaacaggat
     9001 tgagcatttt atcttctcct acaatatcga cataagatac attaaacttc tgacaaatga
     9061 tgtctattag ttccgtagag actgaactag ttccattttc ataccggctc aagctatttc
     9121 gagaaattcc tacaattcgg gaaaagtcgt cttgtgttaa gtcatgtgtt ttacgtaagg
     9181 attttatgtt ctttccaatc atagcaaact cctttatttt tataaatcca ttatagcata
     9241 aaaaagcata acgcaccaaa aatggtgcgt tatttcttgt ttttctatcc taaactttac
     9301 ttctataaaa gtcacctaaa gagctataaa tatttattct tgtattaatt ttttcgatgc
     9361 gcaaacaata tctacaaata catctataac gattcacctt ttaggatttt tattgtcaaa
     9421 attgccttta tctacaaaga caaaatgctt ataaaatagc ttgaaattaa ggattatcac
     9481 ctttttcgtt gtagcaacac tccacatgtg attattaggc tattagcaaa gcgtatccaa
     9541 tacctcaata aagtgttgtt tttactgata ttttaactat attgtatagt ctactattta
     9601 aatctcaatt aggatatttt atagaatacc caaaattcaa caataactaa aagtaagatt
     9661 ccattgtatt tccttgttgg tctttcatat cacgaatttt atttttcaga atattaaagt
     9721 tacaaatttc atctctaata tcgttatccg ctctgtagcc attaatcatc tcagtcagag
     9781 ttttcccttt actaccattc tttatagtag tatttactct ttttatactg ctttcaaaag
     9841 gctcatatgt tttatactta attacttcgt ctttaaaatt aaataaaggt gtatccggct
     9901 tagcattcca taaaataatc aaccacatta tagcattata aagctgcttt gcagtttcat
     9961 tccacttttc aggttgtaaa ttttcactcc ctgtattgtc atattcttgt ctattattta
    10021 catgagaatc acctacaagc ggattaaaaa gaggtagccc tttgtgatta attagttcta
    10081 aaaaatccct tgccgcaccc atgcaacact gaataacttc cttcttgcca tcaattttac
    10141 tctcagcgat aaatacataa tattcatctt caatagttgc tcctgcatca ctatgttttt
    10201 gttgatttgc taacagctta atatgtgctt taggctaaac ttcaaaatct ctaacaattc
    10261 tttgtcttgt ttcatgtcct ctacaattca tttaagttct cctttacaag tttagtaact
    10321 agccttatta tactatataa gatatgaaat gtaccataat cttcatcaac tagtttttag
    10381 aaaatcacaa atccatctgg agagatgaca agctgattct ccaattcttg gcaattgctt
    10441 gctagtgcta ctgcttcttt ctctaaaaga taatcttctg ttgattggtt gaatattgct
    10501 ttgaggatcc gtccttcgta tttccattcc agagctacta gatcagattt gatttcttga
    10561 aggctatact tgccatgcga aatgattact gacgcatatt tccaaatctt aatcagcctc
    10621 ttcataaagt tcagcatatc attgtcactt gatacacgtt cccaaggcat acaacgacga
    10681 caatctggat ctggtcctcc agtcaaggct agctcggttc cgtaataaat gcacggtgtt
    10741 cctttttgta aaaagagaaa ggctaaggct gatttaacca gttgaacatc ttcattggcc
    10801 gtccacagga ttcgctctgt atcatgtgaa tccaagagat taaacatgac ctctgaaatc
    10861 tgctgcttgt aatacataga ctctccattg atttcatcga tgaactggtc tgtcttctta
    10921 attcctcgta agaaatagtc cttgatacta tcagataaag gataattcat gacggcatgg
    10981 aactcatctc catttagcca aggctgagat gtatgccaga cttctcctag gatataaaga
    11041 tcaggatttt tagctaaaac tgccttacga aaatccttcc agaactgatg gtcaatctca
    11101 ttagccacat ccaaacgcca agcatcgata ttaaactctt caatccaata agtcgcaacc
    11161 tttaaaagat aattcttgac ctctggattg gctgtattta gcttaggcat atagtcctcg
    11221 aaaccaaaaa catgataggg taagtctctc ttattaacta gcttttcagt tgtcactggg
    11281 aattgttgaa tatggaacca atccttataa gcagactgtt caccattttt gacgacattt
    11341 ttccattgaa gagattgcga accaatatga ttaaataccg catccagcat gactttcatg
    11401 ccacgatgat gcgcttgatc caccagttcc cgaaaggtct ccttgtctcc aaaatgacgg
    11461 tcaatttcaa agtaatctgt cgtattgtac ttgtgattgc ttgtagattc aaagatggga
    11521 caaagatata gtccagtaat acccaagtct tgcaagtaat ccatatgatc aataatcccc
    11581 tgtaaatcac caccaaagaa atcatcgctc ttaggtgtga cagatgaatc ccagtctaaa
    11641 gtcccttctg ggtttaatag agcattgcca ttggcaaatc tttcaggaaa tatctgatac
    11701 cataccgtat ttgaaaccca gtcaggaacc ttgcaggcat caatctcatg aagataaggc
    11761 aacttaaatc cattcccaat tgcatgaaga ttttctagag aattttccac acacccttta
    11821 tcgccataca aaatattttg accttctgta tctctgagct caaagagata ctggatacgt
    11881 gcaaagtcaa ctgacacttc aacctgccaa tggtcaaata aggtaccaga agttatcttg
    11941 accatttctt ttgtatcctg ataaaactcc tccataaaga taaaagggtc cccatagtgc
    12001 aagttgatgc tttcaatgtc ccctttctta gttcgaattc gaatatggag tttcttatcc
    12061 ttataaagat aggcatactc cgactcaggc ctatggtaaa tagcactcaa ttccatcaat
    12121 ttgtctccta aagtattcat tcaaatttta cgcaaacgtt ttcaagctca atgaatccag
    12181 tatactattt ttgtaaacta tttgcaagga atgtccgttg ttaaaggaac tatcttttaa
    12241 agtatacaaa aagccttaaa aaaggctttc tctatatact aatcctcttt cggttttgaa
    12301 aatacttcta ctcgctgagc taggactttg atttctacag gtaggttatc tgatttatct
    12361 ccgtcaacat ctgactccaa ttcactatct gaagagattt taatattacg cgctttgata
    12421 tactcgatat tatcatttgc gacaacatcc ccttttaata aatcaggaat gacggataat
    12481 ttggagaata tagaggcatc tttcagaatc aaaatgttgg catagccgtc cttgttttct
    12541 tcaaagattt tcttatcagc gaagtaattt gtcaaaagga ccaaaacatg gctagcttca
    12601 ccaacataat ttccattttc tgtctcaacc ttaatgttaa agacctgatc tgtcatgaca
    12661 gacttcatgg tatttacagc ataggttaaa ataccgaatt ttgttttgtc ctctatttca
    12721 acattgtgaa tcgcctcagg cagagaaccg atactaaaga tataaccaaa atagttgtca
    12781 tttgctttac cgatatcaat cttattggtt aaatcaaaat ccagttcgtc aattgcgcca
    12841 tcgatgtctt gattgatttc caaaagtttt gtaatgaggt tacccgtacc gcctgggata
    12901 atccctaact taggaatgta gtctctctca tcaatacctg aaatgacttc attgacagtt
    12961 ccatctccac caaacacaac cactgcatca tactgctcac gagaagcttc ttcagcaaaa
    13021 tgtgttgcat ccagcgcttt ttcggtaatt ttggtttcaa catattcaaa gtattctttt
    13081 gctttattct ccagcttttc tttgtaatcc aaagccttct cgccaccaga agtagggttg
    13141 ataattacca ttgctttttt cattgatttt atccttaatt ttaaacagaa atgtttacat
    13201 ttcgtcgtat gcaagtaaat gtaatcctat tatacaatga aaatacagaa aagagaaatc
    13261 tgacgtactg gagattaata cgcttttatt ctattttccc atcgcctaac tacatccttt
    13321 aagggttcat ccaagtaaga atagtcctta tccttgatcc aatcaggaat accgtaagct
    13381 gcctctgcta tgctacaagt gattgctgcg agagtatcac tgtcgccacc aagtgagatg
    13441 gcatttctta tcgcatcttc gaagtctcta ctttcaagaa aggcgataat ggcttgaggg
    13501 acagtttcct gacatgtttc gttaaaacga tagttaggac ggatttcatc taaagtttga
    13561 gatagattgt aatcgtattc tttttctata taatccttaa ttcgtctttt acactctgta
    13621 ggattgtcgt taattgattg ctcgtactct ctacaataac caccaaagta aaaacgacat
    13681 agaaagatag catcagctgt agccatagcg cctttgacac cttctggatg attatgagtt
    13741 acctctgcag aaagactcgt aagtcctcta gatgatggcc atataccagt tttcgcataa
    13801 aaaccacagt ccatgatcca agcacatgga gaaatacgca tagctgatcc attcccaaag
    13861 ctattataag gctcacggtt atcgctgttt agccacgcat taaaccgagc accgtaatca
    13921 gcattcggat acattctgcc atatttcttc atcgcgtcaa tgaagtcgtc tttttgtcca
    13981 ccattcataa ttgcttctgc aacagcacag gtcataaccg tgtcatctgt aaaaaagcag
    14041 tccttccgaa ataaaggaaa gtcctttgtt ttgatattgt tccattcgta aacagaaccg
    14101 acaatatctc caataattgc tccaagcatc agattcctcc ttgttcattt tgatgctttt
    14161 tatattggtt atctaccata tttattttag aaaataacat cctgttggat tttaaaaatt
    14221 tcattttttt caaaataggg ttttaccatt tctttccacc tagctctatg aaaattgatt
    14281 gattttaaag gagataggcc ataatttccc aatgcataac catcatttac ttcaacaaca
    14341 agtgttctgc catcgcgagt aacaccgata tctagtccat aagctattgg cgcatctttc
    14401 caacatgata tcgcttcatc aattacactt gcatcaaatt gtgcatgata atcacctgta
    14461 tagggtcgaa catctaatac gcgaccatct aacacaaaac aacgccattc agctatgaat
    14521 tctacaacct cactaatcca tataggatag tcgaaaggta gaccaatacc tattaaatca
    14581 tgggttccat taacaactct tccagtaaag acttttgaac cagctttagg cttaataaat
    14641 tttccccaat tatcaggtat attcacaatc tctcctaaaa taccagcata aatctttcga
    14701 ccataaaact ctttaagctc aataggatag tcataaaccg gaacgtttaa gcccatcatt
    14761 tttagtaatg ctctagtctc cattatataa tctacatcta tatcttcact tgttaactct
    14821 tttatttcag aaaaagattg atataaaata acttcttctc cttgtaagta ggcacctact
    14881 tgagcattgt atttattaat tgaaacctca cttagtaatt tactttgtct aatataaaca
    14941 accatttcat cactcctata tcactagtgt tacaccaatt tgtaaaaaat aatagcaatt
    15001 ttgctcttat ttttttgagt aaatagcccc cataatatca tcgaaataat caacggtatt
    15061 taggagtaat tcaataacct gggactttgt tagtcgcatt ccccttctat ctctagcatc
    15121 ttctactaaa ttttcaagtt tctctagatt tttatcatcc aagctaatca ttattctatt
    15181 tttatcggtt gccattttca tcacctcaag ttaattctat cacaggtgta acacttgtgt
    15241 caactggctt ttataataca ttagtttaaa agtggagagg atttttaaca cagtaacttt
    15301 aaatctttgg tattaaaaaa ttttcacaat atttatagaa ataaaatctg tctcaaatca
    15361 gttatcaaat ctagtataaa ttatgagcgg ctactctaat actttccctc taaacaagaa
    15421 aaagacttac actcaagggt tttcttcccc cccttcgtta taacgttttg actcttttac
    15481 tagcaaaggt atatactcac aaggaacttt ggttgactat tgaatctctc caacttcttc
    15541 tttaacatat ccttctacat cttcaatctc tacaaacatt gggtctaagt gacacaagaa
    15601 atgccaaact tcgatccctt tttttctgta aagaatcgct tcaccgtctt cacttccgaa
    15661 aaagcttctg tcgatttcat atccgcggct ttctaagaag tcttttgctt tacgatagtt
    15721 cgtttctctt gtttcgacat aggctttaac ttcatggttg ttaacgacat atgcatcaat
    15781 ttttgaatat ccttcgatca ctctatcatt tttgagggat aaatttgaaa tctctttcca
    15841 aataatgttt acattttcct caggatcgaa cataaattta gataaaggaa caatatttcc
    15901 gttaaaaata atttccatat aatccggtat gtttttagga ttaaaatact ccacttcaaa
    15961 accatcttct gtttccagag tgtatcccgg gatttgagct acaaaggctt tcccatcttc
    16021 tatggaatca aatgctacta aatctttaga ataatcattt tggtacaatt ccaatataac
    16081 catcgataat ctctccattt tcattatcag gctaatgtaa ataagcacgt cacctgacca
    16141 attcaggctc tctgtatcat ctcatcatat ttcctactta ctttacgagt cttataccca
    16201 gaacacacct tatcgacctt cggtctcacc tcgtcgcatt ggctgaacat ctacttttac
    16261 tttgctgatg cttcaactcg tacaagcagt gataccgcct cagtgtgatg cgtcagtggg
    16321 actcaaaagg ttcggggaac cttttgagga ttaactacgt ttctctaata aacttacaca
    16381 ttcaacttgt tcatcattgt ccaaacctat gttgagattt tcttctataa ttggtagctt
    16441 aaaagtaatg gattttagcc attgtccgtt agattgtctt tcttcataaa cttgaatttc
    16501 agaaatcaaa gctgaaatta actgcctacg ctctacatca ttcatgactt tatagagctt
    16561 atcaaaatag attagaacct tatatatgtt atctcctgta agcttttcag cttcaatagt
    16621 ctgtttcttt gctttcgcat caattagtga tgattctaat tcatctattt tgtcatacat
    16681 acgatatagt ctatcatcta aatcctgttt ccttctctta taatgcttat cttcaacatc
    16741 taaattatct atttcctcaa ttagcttaaa ctttgtagaa tgactctttc tcaattcctt
    16801 ttggtaatta tctatttctt tttctatttc agaggtatcc accttcatgt tgattttttc
    16861 ttgcatcata gaagcaaatt tcggattact tactatcttg acaatcacct ctgcaacagc
    16921 atcatctaac aattcttctc taatttgctt actgaatgta cacttatgac ctcttatcat
    16981 ctgcctatgt ttacaaccat agtaataaaa atctttatac tttgtgccat ctttcttttt
    17041 cttgatacac ttgttcccaa acattcccac tccacatatc gggcatttta caattccaga
    17101 aagcaagtgt gtgcgtgtat cttttccttt attcacatgc tcatatttct ttgcttgaga
    17161 ttttagctta acctgagcag cttgccaaac ttcatcggaa actatagctt catgtatccc
    17221 ttcagatatt agatattcat cttgttcaac ctgcttatat tcatttcttg taccatgaac
    17281 tttttctaaa gttcttcttc caaatgctat tttcccatta tatacaggat tctttaatat
    17341 ctttcttata agacctgcat caaacaaagg attcttacca ttctgtcttg ggatttttct
    17401 aattccatga ttctctaagt atttagatat cccattggct cctatcgtag tatttacata
    17461 ctggtcgaaa atcgttctta ttgcaactgc ctcttcctca tttataaaca gcttgccgtc
    17521 ttcaagttta tatccatacg gagcaaagcc accattccat tttccttccc ttgctttttg
    17581 aatgcaacct tccattgttt gaatacggat gttttctctt tctatttcag ccacagctga
    17641 taaaacagaa atcattagtt tcccagcatc tttagatgaa tcaatgccat cttcaacgca
    17701 gataagatta actccataat cctgcattat ctgaagtgta gaaagaacat cagcggcatt
    17761 tcttgcaaat cttgataact taaacacaag aacaaaagat actccatctt ttccagattt
    17821 tatatcttcc atcattcgat tgaactgtat tctaccttca atagacttgc cagacttccc
    17881 ggcatcttca tactctccaa caatttcata atcgttgtaa atagcaaaag ctttcattcg
    17941 tgatttttgt gcctctaacg aatacccctc tatctgtatt gacgtagata ctcgtgtata
    18001 gaggtatact tttatttttt cttttgacat agtattaacc tcaatataat ttttctatat
    18061 catatataat ttttttaatt taagtttgga ctatcatttc aagtatatta taacactttt
    18121 attagtccgt ctcaatttgt gtttttgcca tgtcaaaact atttttcatc tcttgatttt
    18181 ttgctggcgt tggatcgggt agattatcta aatctaaagc accagcatat tttgcaatca
    18241 gatttgctat taaatcagcc aatccattcc agtcattgtc caatatatac ctcctctaaa
    18301 gttttatatc taataattat ttgtttaatt aagttttttg acattgacaa gtgctttgga
    18361 ttagcaacat aggaatctca cctccgcctc tattccggat gagccggctt caaccttaga
    18421 agtatcatta tcctcatttt cttcatagcg gatagggtat ccctccctat attcaaactc
    18481 ttacttatcg ctcactttct ttttgcttag cagaactttt tttgccgaat tattcagccg
    18541 aaagatcttg acggataggt tattacgctc caaaaataat taacgtcttg tcttggtcta
    18601 ttcaattgtt aaggttcaaa atttatcgaa agttattaat ctttttaaaa tttgaccatc
    18661 agaaaatatt tatcttgatg taacaaaatt ctataaatta ccctcttata cttaacagtg
    18721 aaaagaagtc tttcttggta accaattttg aaatagaatt tgcttatata aaaaggtcca
    18781 attcctactg cataagtagc agtgaaaatt agaccctctt ggtaactgtc atctaaaagt
    18841 cttctagcat ttctttaatt ttctaatcgc ctttaaagtg tcatatttat atttttttat
    18901 ctctggcata ctttgatacc tttttaaact taaagtcttt aatagtgcct ttccacctct
    18961 ttttatctat aaagattctc ctacatcata attcattttt ttatttaaac ctttctgtct
    19021 tagtttgtct ttatcttctt cataccattt taagattgtc acatagtggt tttgataggt
    19081 cttaccactg ctttccatgt atctggatag tttatttatc attatatctg tgtgtgagtt
    19141 taatttttct tttagatttt tatattcttc tttgcttaac cttacatttt tgaattctcc
    19201 ataaaaaatg ggggtggact ttttatctat ctctccctct ctctctttat ctatctctat
    19261 atctttctct atctctatct cttgtcggac atgggttgga ctcattaagg acaatgtcct
    19321 ctgtttattt tgtctgtatc ttcttttttt ctctgcccag gctgtttctg atccgattaa
    19381 gtttggtatt tcagttaggt agtattcatc attttctgtt acaacttcta ataagccttg
    19441 attgattaaa taatttactg ttaccattac atcatcgtct gtttcatcta tggttagtgc
    19501 taactctttt ataaaatcac tttctactcc gtcataatag agtttgccct catcttttag
    19561 gcttagtagt agaagtttta ggtagattat cgtataggta tctcctccag atattctcct
    19621 taaccttttt atccttttgt c
//
LOCUS       DBEJHE010000033        19291 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC4 isolate 671759
            SAMN38261586-rid24793303.denovo.33, whole genome shotgun sequence.
ACCESSION   DBEJHE010000033 DBEJHE010000000
VERSION     DBEJHE010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261586
            Sequence Read Archive: SRR26833752
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 19291)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19291)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576136.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576136.1
            Genome Coverage       :: 109x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 19:48:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,067
            CDSs (total)                      :: 2,029
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 131
            CDSs (without protein)            :: 131
            Pseudo Genes (ambiguous residues) :: 0 of 131
            Pseudo Genes (frameshifted)       :: 64 of 131
            Pseudo Genes (incomplete)         :: 59 of 131
            Pseudo Genes (internal stop)      :: 46 of 131
            Pseudo Genes (multiple problems)  :: 32 of 131
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19291
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261586-rid24793303.denovo.33"
                     /strain="GPSC4"
                     /isolate="671759"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            <1..444
                     /locus_tag="ACL3EZ_001664"
     CDS             <1..444
                     /locus_tag="ACL3EZ_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGR0393202.1"
                     /translation="IALKKQLANHSGKKKFHAMKAQAIVTSQGRIVSLDITVNYCHDM
                     KLFKMSCRNIRQVGKILADSGYQGLMKICPQAQTSRKSSKLKPLTAEDKAYNHALSKE
                     RSKVENIFAKVKTFKMFSTTYRNHRKRFGLRMNLIAGIINHELGF"
     gene            complement(496..822)
                     /locus_tag="ACL3EZ_001665"
     CDS             complement(496..822)
                     /locus_tag="ACL3EZ_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0393203.1"
                     /translation="MILWSFDFANDHAHAFFMDNIEWSHADSYFLSFVSDDVEERYTE
                     NVYLDSLSVKQKFKFIFDFGDEWRFECQVLREIETEDEEAYLVRSVGTSPEQYPDYDG
                     FDYEEW"
     gene            complement(1149..3029)
                     /locus_tag="ACL3EZ_001666"
     CDS             complement(1149..3029)
                     /locus_tag="ACL3EZ_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HGR0393204.1"
                     /translation="MVRFIGLSPKQTQAIEVLKGHISLPDVEVAVTQSDQASISIQGE
                     EGHYQLTYRKPHQLYRALSLLVTVLAEADKVEIEEQAAYEDLAYMVDCSRNAVLNVAS
                     AKQMIEVLALMGYSTFELYMEDTYQIEGQPYFGYFRGAYSAEELQEIEAYAQQFDMTF
                     VPCIQTLAHLSAFVKWGVKEVQELRDVEDILLIGEEKVYDLIDGMFATLSKLKTRKVN
                     IGMDEAHLVGLGRYLILNGVVDRSLLMCQHLERVLDIADKYGFHCQMWSDMFFKLMSA
                     DGQYDRDVEIPEETRVYLDRLKDRVTLVYWDYYQDSEEKYNRNFRNHHKISHDLAFAG
                     GAWKWIGFTPHNHFSRLVAIEANKACRANQIKEVIVTGWGDNGGETAQFSILPSLQIW
                     AELSYRHDLDSLSAHFKTNTGLTVEDFMQIDLANLLPDLPGNLSGINPNRYVFYQDVL
                     CPILDRHMTPEQDKPHFAQAAETLANIKEKAGNYAYLFETQAQLNAILSSKVDVGRRI
                     RQAYQADDKESLQQIARQELPELRSQIEDFHALFSHQWLKENKVFGLDTVDIRMGGLL
                     QRIKRAESRIEVYLAGQLDRIDELEVEILPFTDFYADKDFAATTANQWHTIATASTIY
                     TT"
     gene            complement(3023..3892)
                     /locus_tag="ACL3EZ_001667"
     CDS             complement(3023..3892)
                     /locus_tag="ACL3EZ_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HGR0393205.1"
                     /translation="MTIATIDIGGTGIKFASLTPDGKILDKTSISTPENLEDLLAWLD
                     QRLSEQDYSGIAMSVPGAVNQETGVIDGFSAVPYIHGFSWYEALSSYQLPVHLENDAN
                     CVGLSELLAHPELENAACVVIGTGIGGAMIINGRLHRGRHGLGGEFGYMTTLAPAEKL
                     NNWSQLASTGNMVRYVIEKSGHTDWDGRKIYQEAAAGNALCQEAIERMNRNLTQGLLN
                     IQYLIDPDVISLGGSISQNPDFIQGVKKAVEDFVDAYEEYTVAPVIQACTYHADANLY
                     GALVNWLQEEKQW"
     gene            complement(3976..6621)
                     /locus_tag="ACL3EZ_001668"
     CDS             complement(3976..6621)
                     /locus_tag="ACL3EZ_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000432759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HGR0393206.1"
                     /translation="MENVVVHIISHSHWDREWYLPFESHRMQLVELFDNLFDLFENDP
                     EFKSFHLDGQTIVLDDYLQIRPENRDKVQRYIDEGKLKIGPFYILQDDYLISSEANVR
                     NTLIGQQEAAKWGKSTQIGYFPDTFGNMGQAPQILQKSGIHVAAFGRGVKPIGFDNQV
                     LEDEQFTSQFSEMYWQGVDGSRVLGILFANWYSNGNEIPVDKDEALTFWKQKLSDVRA
                     YASTNQWLMMNGCDHQPVQKNLSEAIRVANELFPDVIFVHSSFDEYVQAVEGALPEHL
                     STVTGELTSQETDGWYTLANTSSSRIYLKQAFQENSNLLEQVVEPLTIITGGHNHKDQ
                     LTYAWKTLLQNAPHDSICGCSVDEVHREMETRFAKVNQVGNFVKSNLLNEWKGKIATD
                     KAQSDYLFTVINTGLHDKVDTVCTVIDVATCDFKELHPTEGYKKMAALILPSYRVEDL
                     DGRPVEVTIEDLGANFEYDLPKDKFRQARIARQVRVTIPVHLAPLSWTTFQLLEGEQE
                     HREGIYQNGVIDTPFVTVSVDDNITVYDKTTHEAYEDFIRFEDRGDIGNEYIYFQPKG
                     TEPIFAELKGHEVLENTDRYAKILLKHELTVPVSADEKLEEEQQGIIEFMKREAGRSE
                     ELTNIPLETELIVFVDNPQIRFKTRFTNTAKDHRIRLLVKTHNTRPSNDSESIYEVVT
                     RPNKPAASWENPENPQHQQAFVSLYDDEKGVTVSNKGLNEYEILGDNTIAVTILRASG
                     ELGDWGYFPTPEAQCLREFEVEFAIECHQAQERFSAYRRAKALQTPFTSLQLARQEGS
                     VVATGSLLSHSVLSIPQVCPTAFKVAENEEGYVLRYYNMSQENVRISEHQQTILDLLE
                     RPYPVHSGLLAPQEIRTEFIKKEEI"
     gene            complement(6712..7992)
                     /locus_tag="ACL3EZ_001669"
     CDS             complement(6712..7992)
                     /locus_tag="ACL3EZ_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HGR0393207.1"
                     /translation="MIYSKEIVREWLDEVAERAKDHPEWVDVFERCYTDTLDNTVEIL
                     EDGSTFVLTGDIPAMWLRDSTAQLRPYLHVAKRDALLRQTIAGLVKRQMTLVLKDPYA
                     NSFNIEKNWKGHHETDHTDLNGWIWERKYEVDSLCYPLQLAYLLWKETGETGQFDETF
                     VAATKEILHLWTVEQDHKNSPYRFVRDTDRKEDTLVNDGFGPDFAVTGMTWSAFRPSD
                     DCCQYSYLIPSNMFAVVVLGYVQEIFAALNLADSQSVIADAKRLQDEIQEGIENYAYT
                     TNSKGEKIYAFEVDGLGNASIMDDPNVPSLLAAPYLGYCSVDDEVYQATRRTILSPEN
                     PYFYQGEYASGLGSSHTFYRYIWPIALSIQGLTTRDKAEKKFLLDQLVACDGGTGVMH
                     ESFHVDDPTLYSREWFSWANMMFCELVLDYLDIR"
     gene            8163..10247
                     /locus_tag="ACL3EZ_001670"
     CDS             8163..10247
                     /locus_tag="ACL3EZ_001670"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000803403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HGR0393208.1"
                     /translation="MKPLLETIDTRFGTTNKHAFSRGNTLPYTGVPFGMNYFVPQTSD
                     QDGSWFFDPHLPIFQGIRLTHQPSPWIGDYSWLLLTPVTGQLGGDSLFHRQSSYDRDK
                     ASFQPHYLKIFSLRYQIETQLTPTCYGASIRLKQKQGKALSLYLHAADELTVEQVDKR
                     TLALRQEGKTETNKNSLTMFTALQMNTDILAISQEAGDWRIDLVSSQTEMQLATSFIS
                     PSQALINLPQEDFDSCKASAQADWENLLHRFDVIETGEANRTFFDHCLYRLFLFPQTF
                     YEVDESGQAIHMDLATGTVKPGVLFSNNGFWDTFRTTFPLFALIIPEHYQRFLEGFLN
                     SYRDTGFLPKWLAPDERGMMPGTLLDGIIADSACKDMAPDLEGELFQAMLKTASKADP
                     LGINGRHGLAQYQELGYLSTDHHESVSHTLDYAYSDFCIANCAKKLKNIEIAETYKAA
                     SQNYRQLFDAETGYMRARDNQGNFHPDFSLYSWGRDYAECSAIQATLGVLHDIPGLIQ
                     LMGGKETFSNYLLKACQDAPLFETTGYGYEIHEMSEMATAPFGQIAISNQPSFHIPYL
                     FRYSDYPDYTALLIKTLRQKAFHPSWEAYPGDEDNGSLSAWYIWSALGFYPTCPGKPS
                     YDLGIPLFDHLRVYLAKEDKWLDIHTKQNHNHFNFVKECRLDKTLVSTIQHQDLLKAE
                     QLTFTLSWLPSH"
     gene            complement(10287..11966)
                     /locus_tag="ACL3EZ_001671"
     CDS             complement(10287..11966)
                     /locus_tag="ACL3EZ_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000721501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-fucosidase"
                     /protein_id="HGR0393209.1"
                     /translation="MKKIKPHGPLPSQTQLAYLGDELAAFIHFGPNTFYDQEWGTGQE
                     DPERFNPSQLDAREWVRVLKETGFKKLILVVKHHDGFVLYPTAHTDYSVKVSPWRRGK
                     GDLLLEVSQAATEFDMDMGVYLSPWDAHSPLYHVDREADYNAYYLAQLKEILSNPNYG
                     NAGKFAEVWMDGARGEGAQKVNYEFEKWFETIRDLQGDCLIFSTEGTSIRWIGNERGY
                     AGDPLWQKVNPDKLGTDAELNYLQHGDPSGTIFSIGEADVSIRPGWFYHEDQDPKSLE
                     ELVEIYFHSVGRGTPLLLNIPPNQAGLFDAKDIERLYEFATYRNELYKEDLALGVEVS
                     GPALSADFACRHLTDGLETSSWANDADLPIQLELDLGFPKTFDVIELREDLKLGQRIA
                     AFHVQVEVDGVWQEFGSGHTVGYKRLLRGAVVEAQKIRVVITESQALPLLTKISLYKT
                     PRLSQTVAVQGLAFAEKSLAVAKGETLHFRIERSESSSSLETKISIQPGTGVHGVAYQ
                     DEIQVLQFQAGESKKDLHLPTLYFAGDKTLDFYLNLTVDGQLVDQLQVQVS"
     gene            12721..13950
                     /gene="arcA"
                     /locus_tag="ACL3EZ_001672"
     CDS             12721..13950
                     /gene="arcA"
                     /locus_tag="ACL3EZ_001672"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016990 - arginine deiminase activity
                     [Evidence IEA];
                     GO_process: GO:0019546 - arginine deiminase pathway
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HGR0393210.1"
                     /translation="MSSHPIQVFSEIGKLKKVMLHRPGKELENLLPDYLERLLFDDIP
                     FLEDAQKEHDAFAQALRDEGIEVLYLEQLAAESLTSPEIRDQFIEEYLDEANIRDRQT
                     KVAIRELLHGIKDNQELVEKTMAGIQKVELPEIPDEAKDLTDLVESDYPFAIDPMPNL
                     YFTRDPFATIGNAVSLNHMFADTRNRETLYGKYIFKYHPVYGGKVDLVYNREEDTRIE
                     GGDELVLSKDVLAVGISQRTDAASIEKLLVNIFKKNVGFKKVLAFEFANNRKFMHLDT
                     VFTMVDYDKFTIHPEIEGDLHVYSVTYENEKLKIVEEKGDLAELLAQNLGVEKVHLIR
                     CGGGNIVAAAREQWNDGSNTLTIAPGVVVVYDRNTVTNKILEEYGLRLIKIRGSELVR
                     GRGGPRCMSMPFEREEV"
     gene            14008..15024
                     /gene="argF"
                     /locus_tag="ACL3EZ_001673"
     CDS             14008..15024
                     /gene="argF"
                     /locus_tag="ACL3EZ_001673"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004585 - ornithine carbamoyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0042450 - arginine biosynthetic process via
                     ornithine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HGR0393211.1"
                     /translation="MTNSVFQGRSFLAEKDFTRTELEYLIGLSAHLKDLKKRNIQHHY
                     LAGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVQENFGRLEGLTLV
                     YCGDGRNNVANSLLVTGAILGVNVHIFSPKELFPEKEIVELAEGFAKESGAHVLITED
                     ADEAVKDADVLYTDVWVSMGEEDKFAERVALLKPYQVNMDLVKKAGNENLIFLHCLPA
                     FHDTHTVYGKDVAEKFGVEEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLY
                     IPKV"
     gene            15189..16136
                     /gene="arcC"
                     /locus_tag="ACL3EZ_001674"
     CDS             15189..16136
                     /gene="arcC"
                     /locus_tag="ACL3EZ_001674"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003025409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008804 - carbamate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HGR0393212.1"
                     /translation="MANRKIVVALGGNAILSSDPSAKAQQEALVETAKHLVKLIKNGD
                     DLIITHGNGPQVGNLLLQHLASDSEKNPAFPLDSLVAMTEGSIGFWLKNALQNALLDE
                     GIEKNVASVVTQVVVDKNDPAFVNLSKPIGPFYSEEEAKAEAEKSGATFKEDAGRGWR
                     KVVASPKPVDIKEIETIRTLLNNGQVVVAAGGGGIPVVKENNGHLTGVEAVIDKDFAS
                     QRLAELVDADLFIVLTGVDYVFVNYNKPNQEKLEHVNVAQLEEYIKQDQFAPGSMLPK
                     VEAAIAFVNGRPEGKAVITSLENLGALIESESGTIIEKG"
     gene            16347..17858
                     /locus_tag="ACL3EZ_001675"
     CDS             16347..17858
                     /locus_tag="ACL3EZ_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004191872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HGR0393213.1"
                     /translation="MSEKAKKGFKMPSSYTVLLIIIAIMAVLTWFIPAGAFIEGIYET
                     QPQNPQGIWDVLMAPIRAMLGTHPEEGSLIKETSAAIDVAFFILMVGGFLGIVNKTGA
                     LDVGIASIVKKYKGREKMLILVLMPLFALGGTTYGMGEETMAFYPLLVPVMMAVGFDS
                     LTGVAIILLGSQIGCLASTLNPFATGIASATAGVGTGDGIVLRLIFWVTLTALSTWFV
                     YRYADKIQKDPTKSLVYSTRKEDLKHFNVEESSSVESTLSSKQKSVLFLFVLTFILMV
                     LSFIPWTDLGVTIFDDFNAWLTGLPVIGNIVGSSTSALGTWYFPEGAMLFAFMGILIG
                     VIYGLKEDKIISSFMNGAADLLSVALIVAIARGIQVIMNDGMITDTILNWGKEGLSGL
                     SSQVFIVVTYIFYLPMSFLIPSSSGLASATMGIMAPLGEFVNVRPSLIITAYQSASGV
                     LNLIAPTSGIVMGALALGRINIGTWWKFMGKLVVAIIVVTIALLLLGTFLPFL"
     gene            17880..19211
                     /locus_tag="ACL3EZ_001676"
     CDS             17880..19211
                     /locus_tag="ACL3EZ_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000686986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HGR0393214.1"
                     /translation="MKIDITNQVKDEFLISLKTLISYPSVLNEGENGTPFGQAIQDVL
                     EKTLEICRDIGFTTYLDPKGYYGYAEIGQGAELLAILCHLDVVPSGDEADWQTPPFEA
                     TIKDGWVFGRGVQDDKGPSLAALYAVKSLLDQGIQFKKRVRFIFGTDEETLWRCMARY
                     NTIEEQASMGFAPDSSFPLTYAEKGLLQVKLHGPGSDQLELEVGGAFNVVPDKANYQG
                     PLYEQVCNGLKEAGYDYQTTEQTVTVLGVPKHAKDASQGINAVIRLATILAPLQEHPA
                     LSFLATQAGQDGTGRQIFGDIADEPSGHLSFNVAGLMINHKRSEIHIDIRTPVLADKE
                     ELVELLTRCAQNYQLRYEEFDYLAPLYVAKDSKLVSTLMQIYQEKTGDNSPAISSGGA
                     TFARTMPNCVAFGALFPGAKQTEHQANECAVLEDLYRAMDIYAEAVYRLAT"
BASE COUNT         5462 a         4365 c         3961 g         5503 t
ORIGIN      
        1 atcgccctaa aaaaacaatt agcgaatcat tctggtaaaa agaaatttca cgctatgaag
       61 gctcaagcga ttgtcacaag tcaagggaga attgtttctt tggatatcac tgtgaactat
      121 tgtcatgata tgaagttgtt caaaatgagt tgcagaaata tcagacaagt tggtaaaatc
      181 ttggctgaca gtggttatca agggctcatg aagatatgtc ctcaagcaca aacttcacgt
      241 aaatccagca aactcaagcc actaacagct gaagataaag cctataacca tgcgctatcc
      301 aaggagagaa gcaaggttga gaacatcttt gccaaagtaa aaacgtttaa aatgttttca
      361 acaacctatc gaaatcatcg taaacgcttc ggattacgaa tgaatttgat tgctggtatt
      421 atcaatcatg aactaggatt ctagttttgc aggaagtcta ttgaaatact aagcctacac
      481 agactgattt caattttacc attcttcata gtcaaaacca tcataatctg gatattgttc
      541 tggcgacgtt ccaaccgaac gtacgagata agcttcttcg tcctctgtct cgatttctct
      601 cagcacttgg cattcaaaac gccattcatc accgaagtcg aaaataaact taaatttttg
      661 tttgacactt aggctatcca gatagacatt ttctgtgtaa cgttcttcaa catcgtcact
      721 aacaaagcta agaaagtaag aatctgcatg actccactca atattatcca tgaaaaatgc
      781 gtgagcatga tcatttgcaa aatcaaaact ccataaaatc acatctgcta gttccgctaa
      841 cgtttttgtt tttggaatct atatatgtcg gtagcaacct tttttaaatt tgacggaaat
      901 gatccaagcc tctacagatg ctggcttttc agcttctatt tcttgtttta ctaattttaa
      961 ctgtagcatt tgaaaccaga taattcttct gtttcacgcg aaacaccctg cgccaagcaa
     1021 ggtgttcttg tttttatact caatgaaaat caaagagcaa actaggaagc tagctgcagg
     1081 ctgctcaaaa cactgttttg aggttgtaga tggaagctga cgtggtttga agagattttc
     1141 gaagagtatt aagtcgtata aatcgtcgaa gctgtcgcaa tggtatgcca ctggttagct
     1201 gtagttgctg cgaaatcctt gtctgcgtag aagtcagtaa atggtaggat ttcaacttcc
     1261 agctcgtcga tgcggtcaag ctggccagcc agataaacct cgatacggct ttctgctcgt
     1321 ttgatgcgtt gcaagagtcc gcccatacgg atgtcaactg tatccaaacc aaagaccttg
     1381 ttttctttca gccattggtg actaaagagg gcatggaagt cttcaatttg gcttctaagt
     1441 tctggtaatt cttgtctggc gatttgttgt aaactttctt tatcatccgc ttggtaggcc
     1501 tgacgaatgc gtcgtcccac atctactttg ctacttaaaa tagcattcaa ctgggcctga
     1561 gtttcaaaga gataagcata gtttccagct ttttctttaa tgttagcaag cgtctcagca
     1621 gcctgagcga agtgcggttt gtcctgttca ggtgtcatgt gtcggtcaag tatcggacag
     1681 agaacatcct gataaaagac atatcggttg ggattgatgc cactgagatt gcctggtagg
     1741 tctggtaaga ggttggcaag gtcaatctgc ataaaatcct caaccgttag accagtattg
     1801 gtcttgaagt gcgcagacaa actatctagg tcatggcgat agctgagttc tgcccagatt
     1861 tgcaagcttg gtaggataga gaactgggca gtttcacccc cattgtctcc ccaacccgtt
     1921 acgatgactt ctttaatctg attggcacgg caggctttat tagcctcgat agccactaga
     1981 cggctaaaat ggttgtgagg tgtaaagcca atccacttcc aagctccccc tgcaaatgca
     2041 aggtcatggc taatcttgtg atgattgcgg aaattacggt tgtatttttc ctcgctatcc
     2101 tgataataat cccagtaaac cagagtcaca cggtctttga gacggtctag gtagacacga
     2161 gtttcctctg gaatttccac atcacggtcg tactggccat ccgctgacat gagtttgaag
     2221 aacatatcac tccacatctg gcagtggaaa ccatatttgt cagcaatatc cagcacgcgc
     2281 tccaagtgtt ggcacatgag gagactacga tccacaacac cgttcaaaat caggtagcgt
     2341 cccaaaccaa ccaagtgggc ttcgtccatc ccgatattga ccttgcgagt cttcagttta
     2401 gacaacgtgg caaacatgcc atcaatcagg tcataaacct tttcttcgcc aatgagaaga
     2461 atgtcctcta catcacggag ctcctgcact tccttgacac cccatttgac aaaggccgac
     2521 aagtgggcca aggtctggat gcatggtaca aaggtcatgt caaactgttg agcataggct
     2581 tcgatttcct gcaactcctc tgctgaataa gctccacgga aatagccaaa gtaaggctgt
     2641 ccttcaatct ggtaagtgtc ttccatgtaa agctcaaagg ttgagtagcc catgagagcc
     2701 aagacctcaa tcatctgctt ggcagaagcc acattcagca ccgcatttcg agaacagtca
     2761 accatgtaag ccaaatcttc gtaagctgct tgttcctcaa tctctacttt atcagcttct
     2821 gctagaactg ttaccaacaa ggacaaggca cgataaagtt ggtgaggttt gcgataggtc
     2881 aattgatagt gaccttcctc accctggata gagatagatg cttggtcaga ctgagtgaca
     2941 gccacttcca catctggtag agaaatgtga ccttttaaaa cctcaatagc ttgcgtttgt
     3001 ttgggactaa gtcctataaa tcttaccact gcttttcctc ctgtagccag ttgacaagag
     3061 caccgtagag attggcatct gcgtgatagg tgcaggcctg gataactggt gcgaccgtgt
     3121 attcttcgta ggcatcgaca aagtcttcaa cagccttctt aacaccttgg ataaaatctg
     3181 gattttgact gatagagcca cccagactga tgacatctgg atcgatgaga tactggatat
     3241 tgagcaagcc ttgcgtcaaa ttgcggttca tgcgctcaat ggcttcttga caaagagcat
     3301 taccagctgc ggcctcttgg taaatcttgc gaccgtccca atcagtatga ccagattttt
     3361 caatcacgta tcgtaccata ttcccagttg atgctagttg cgaccagtta ttaagttttt
     3421 cagcaggggc aagggttgtc atgtagccaa attctccacc cagaccgtgg cgacctcgat
     3481 gaagtctacc attgataatc atggctccgc caatccctgt cccaatcacg acacaggctg
     3541 cattttcaag ctctggatga gctagtagtt cactgagtcc aacgcagttg gcatcatttt
     3601 ctaaatggac aggtagctga taagagctaa gcgcctcata ccaagaaaag ccatggatgt
     3661 agggcaccgc actgaagcca tcaatcacac ctgtctcttg attgactgca cctggaacac
     3721 tcatagcaat cccactgtaa tcctgttctg acaagcgttg atctagccac gctagtaaat
     3781 cctccaagtt ttcaggcgtt gaaatacttg tcttatccag tattttccca tcaggagtca
     3841 gactggcaaa cttaatccca gtccctccga tatcaatcgt tgcaatggtc attgttttta
     3901 ccataaaaag gggcgaatca gcagttagtt cttacttttt cgcccctcct ttcttttgat
     3961 gtttactttt tgaaattaaa tttcttcttt tttgatgaat tctgtacgaa tctcttgtgg
     4021 agccaatagt cctgaatgaa ctggatatgg tcgctcaagt aagtcaagaa tggtttgttg
     4081 atgttctgat atgcgcacat tttcttgact catattatag taacggagga catagccttc
     4141 ttcattttcc gccactttaa aggctgttgg acaaacttgc ggtatgctga gaacagaatg
     4201 gctcaagagg ctaccagtcg caaccacgct tccttcctgt ctagcaagct gaaggctggt
     4261 aaacggtgtc tgcaaggctt tggcacgacg ataggctgag aagcgttctt gggcttggtg
     4321 gcattcaatc gcaaattcga cttcaaactc acgcaagcat tgtgcttctg gcgttgggaa
     4381 gtagccccag tcacctagct cacctgatgc acgcaaaatg gtcacggcaa tggtgttatc
     4441 cccaaggatt tcgtattcat tcaatccctt gttggataca gtcacccctt tttcatcgtc
     4501 atacagactg acaaaagctt gttggtgttg aggattttca ggattttccc atgaagcagc
     4561 tggtttgttt ggtcgtgtca ccacctcata gatactttca gaatcattgc ttggacgcgt
     4621 gttatgagtc ttgaccaaga gacggatacg gtgatccttg gcagtgttag taaagcgagt
     4681 cttgaagcgg atttgtggat tgtcaacaaa gacaatcaac tcagtttcca gaggaatgtt
     4741 tgtcaattct tctgaccgtc cagcctcacg cttcataaac tcgatgatac cttgttgctc
     4801 ttcttctagc ttttcatccg cactgacagg cacggtcaat tcatgtttga gcaagatttt
     4861 agcatagcga tctgtgtttt ccaagacctc gtggccctta agctctgcaa agattggctc
     4921 tgttcctttt ggttggaaat agatatactc gtttccgatg tcaccccggt cttcgaagcg
     4981 gataaagtct tcataggctt cgtgagttgt cttgtcatag actgtgatgt tgtcatccac
     5041 actcaccgtt acgaatggtg tatcaatcac tccgttttgg taaataccct cacggtgttc
     5101 ttgttctcct tccagcaatt ggaaggttgt ccaagaaagc ggtgctaggt gaactggaat
     5161 ggtcacgcgc acttgtcgag caatacgagc ttggcggaac ttatcttttg gtaaatcgta
     5221 ttcaaaatta gctccgaggt cttcgattgt aacctctaca ggacgaccat ccaagtcctc
     5281 cacacggtaa cttggcaaga taagagcagc catctttttg tagccttctg ttgggtgcaa
     5341 ttccttgaaa tcacaagtcg ccacatcaat cactgtgcag acagtatcga ccttatcatg
     5401 caagcctgtg ttaatgacag taaagagata gtcactttga gccttatccg tagcaatttt
     5461 acccttccac tcgttgagca aattactttt aacaaagttt cctacttggt tgaccttggc
     5521 aaaacgcgtt tccatctcgc ggtgaacttc gtccacgcta cagccacaga tactatcatg
     5581 tggcgcattc tgcaaaagtg ttttccaagc ataggtcaac tggtccttgt ggttgtgtcc
     5641 accagtgata atagtcaagg gttctaccac ttgctctagg aggttgctat tttcttggaa
     5701 ggcttgtttt aggtaaatgc gggatgaaga agtgttggca agtgtgtacc agccatctgt
     5761 ttcctgactg gtcaactcgc ctgtaacagt tgataagtgt tcaggaagcg caccttctac
     5821 agcttgaaca tattcatcaa aagaactatg aacaaagatt acatccggga agagttcatt
     5881 tgccacacga atggcttcgc tcagattttt ctgtacaggc tggtggtcac agccgttcat
     5941 catcaaccat tggttggtcg aagcgtaggc acgcacatct gacaattttt gtttccagaa
     6001 ggtcaaggcc tcatctttgt caactgggat ttcattccca ttactgtacc agttggcaaa
     6061 gagaatacct aaaacacgac taccatccac accctgccag tacatttctg aaaactggga
     6121 tgtaaactgc tcatcttcaa ggacttggtt gtcaaatcca atcggcttca caccacgacc
     6181 aaaggccgcc acgtgaatgc ctgatttttg aagaatttga ggcgcttgtc ccatatttcc
     6241 aaaggtatct ggaaagtagc caatctgggt tgatttaccc catttggcag cttcttgttg
     6301 accaatcaag gtattgcgga cattggcttc actggagatc aagtagtcat cctgcaagat
     6361 gtaaaaggga ccaattttaa gtttgccctc gtcaatgtag cgttggacct tgtcacgatt
     6421 ttcagggcga atttgtaagt agtcgtcaag gacaatagtt tgtccatcca agtggaaact
     6481 cttgaactca gggtcatttt caaagagatc aaagagattg tcaaacaatt ccaccaactg
     6541 catacgatgg ctttcaaaag gcaagtacca ctcacggtcc cagtgactat gtgagataat
     6601 atgtacaaca acattttcca tgaagtaaaa cctcattcta aatttaaatt ttaacgtttt
     6661 aaatgtaaac ttgtgattct gataagaatc ggttgagcta aagcgagccc cttagcgaat
     6721 atccaagtaa tccaagacca actcacagaa catcatgtta gcccaggaga accattcacg
     6781 agagtagagg gtcggatcat ctacatgaaa gctttcgtgc atgacacctg taccaccatc
     6841 gcaggcaacc agctgatcca gcaagaattt tttctctgcc ttatctcttg ttgtcaatcc
     6901 ttggatagaa agggcgattg gccagatata gcgatagaag gtatgagaac ttccgagacc
     6961 gctagcgtat tctccttggt agaaatatgg attttcaggg ctcaaaatgg tacgacgagt
     7021 agcttgatac acttcatcat cgaccgaaca gtagcccaga tagggcgcag ctagtagact
     7081 tggtacattt ggatcatcca tgatgctggc atttcctagg ccatccactt caaaagcgta
     7141 aatcttttcg cccttgctgt tggtggtgta agcgtagttt tcgattcctt cttggatttc
     7201 atcctgaaga cgcttggcat cagcaataac actctggcta tcagctaggt ttaatgctgc
     7261 gaagatttct tgcacataac ccaagactac tacagcaaac atatttgacg gaatcaagta
     7321 actatactgg caacagtcat cactcggacg aaaggctgac caagtcatac ctgtcactgc
     7381 aaagtcaggt ccaaagccat catttaccaa ggtgtcttcc ttacggtccg tatctcggac
     7441 aaaacgataa ggagagttct tgtggtcttg ttcaactgtc catagatgga gaatttcctt
     7501 agtcgctgcg acaaaagtct catcaaactg accagtctcg ccagtctctt tccagaggag
     7561 ataagccaac tgcaaaggat agcaaagtga atccacctca tacttgcgct cccagatcca
     7621 gccgttaagg tctgtgtggt cagtctcgtg gtgccctttc cagttcttct caatgttgaa
     7681 ggagttagca tagggatcct tgagtaccaa ggtcatctga cgtttgacca aacctgcaat
     7741 ggtctgacgc aggagggcat ctcttttagc tacatgaagg tagggtctga gttgggctgt
     7801 cgaatctcga agccacatgg caggaatatc cccagtcaag acaaaagttg aaccatcttc
     7861 taagatttca accgtattgt ccaaggtatc ggtgtagcaa cgctcgaaaa catccaccca
     7921 ctctggatgg tccttagccc gctctgctac ttcatctagc cattctctaa caatttcttt
     7981 cgaataaatc atcgtgcaat tccctctttc aaacaagttt catgttcagt atatagcttt
     8041 tgagacagaa aatacataca caaatgatag tcatttttct acaaaatagt tatttttgaa
     8101 actccttttc taaaggccct ctttttctga tataatgtag aaaaacagct aaaggaaaga
     8161 ctatgaaacc actacttgaa accatcgata cccgctttgg aactaccaac aagcatgcct
     8221 tttctcgggg aaataccctg ccatacacag gcgtgccttt tgggatgaat tactttgtgc
     8281 cccagaccag tgaccaggat ggatcttggt tttttgatcc gcatctgcct atctttcagg
     8341 ggattcgatt aactcaccag cccagtcctt ggattgggga ctactcttgg ctccttctga
     8401 cacctgtcac aggtcagctt gggggagaca gtctctttca ccgccaatct tcctatgata
     8461 gggataaggc ctctttccaa cctcattatc taaagatttt ctccctgcgc tatcagattg
     8521 aaacccagct cacaccgact tgctacggtg cttctattcg tttgaagcaa aagcaaggca
     8581 aagccctctc cctctatctt cacgcagcag atgaactgac agtagagcaa gtagataagc
     8641 gaactcttgc cctgcgacaa gaaggtaaaa ctgaaaccaa caaaaattcg ctaacgatgt
     8701 tcactgccct acaaatgaac acggatattc ttgctatcag ccaagaagct ggagactggc
     8761 gaattgactt agtaagtagt caaaccgaga tgcaactagc cacttctttc atctctcctt
     8821 ctcaagctct aatcaatcta cctcaagaag attttgatag ctgtaaagca agtgcccaag
     8881 cggattggga aaatctcctc catcgttttg atgttataga gacaggagag gctaaccgaa
     8941 ccttctttga ccactgtctc tacagactct tcctcttccc acagactttt tatgaggttg
     9001 atgagtcagg gcaagccatc cacatggatc tggctactgg tactgtcaag cctggtgtcc
     9061 tctttagcaa caatggtttc tgggatacct tccgcaccac cttccccctc tttgccctta
     9121 tcataccgga gcactatcaa cgctttttag aaggtttcct caatagctac cgcgatactg
     9181 gtttccttcc aaaatggctg gctccagatg aacggggtat gatgccaggt acacttttag
     9241 acggtattat cgcagatagc gcctgcaagg acatggcccc cgacctagaa ggagaactct
     9301 tccaagccat gctcaaaaca gccagcaaag ccgaccctct cggcatcaat ggccgccacg
     9361 gactagccca ataccaagaa ctaggttacc tctctaccga ccaccacgaa agtgttagcc
     9421 atactctaga ctatgcctat agtgactttt gtatcgccaa ctgtgccaaa aaactaaaaa
     9481 acatagaaat cgctgaaacc tacaaggctg cttcacaaaa ttaccgccag ctatttgacg
     9541 ctgagacagg ttacatgcga gcacgagaca atcaaggaaa ctttcaccct gacttctctc
     9601 tttatagttg ggggcgagac tacgctgaat gctctgccat tcaagctact ttaggcgttc
     9661 tccacgacat ccctggctta atccaactga tgggtggaaa agaaaccttt agcaactatc
     9721 ttttgaaagc ctgtcaagat gctcccctct ttgaaacaac aggctatggt tacgaaattc
     9781 acgaaatgag cgagatggct actgctcctt ttggacaaat agccatttcc aaccagccta
     9841 gtttccacat tccttatctc ttccgctaca gcgattaccc tgactacact gcccttctta
     9901 tcaagacgct ccgtcagaaa gcttttcacc caagttggga agcctatcct ggagatgaag
     9961 acaatggtag tctctctgct tggtacatct ggtcagctct cggattttat ccaacctgtc
    10021 caggaaaacc aagctatgac ctcggaatcc ctctctttga ccatctacga gtctacctcg
    10081 ctaaagaaga taaatggctg gatatccata ctaaacaaaa ccacaaccat tttaactttg
    10141 tcaaagaatg ccgactggac aaaacactcg tatcaactat tcaacaccaa gacctcttaa
    10201 aagctgaaca actaactttc accctcagct ggttaccaag tcactaataa ccaaaagaac
    10261 ctttgcatcg cgcaaaggtt cttcttttat gaaacttgga cttgaagttg atccacaagc
    10321 tgaccatcca ccgttaggtt cagatagaaa tccaaggttt tatctcctgc gaaatacagg
    10381 gttggtagat gcaaatcttt tttgctttcc cctgcttgga attgaaggac ttgaatctca
    10441 tcctgatagg cgacaccatg gacacctgtc cccggttgaa tcgaaatctt agtctctaaa
    10501 gaggagctac tttcactacg ttcaatccta aaatgaagag tctctccctt tgccacagct
    10561 aggctttttt ctgcaaatgc tagcccctga acagctactg tttgtgataa cctaggagtt
    10621 ttatagagtg aaatcttggt caacaaaggc aaagcctgtg attctgtaat gactacacgt
    10681 atcttctgtg cttcaacaac tgctcctcgt aagagacgtt tgtaaccaac agtatgaccc
    10741 gaaccaaact cctgccagac accatccacc tctacttgca catgaaaagc agcgattcgt
    10801 tgccctagct tcaaatcttc tcttaactca attacatcaa aagttttagg aaaacctaag
    10861 tcgagttcta actggatggg caagtctgca tcgtttgccc aagagctggt ctcaaggccg
    10921 tctgtcaaat ggcgacaagc aaagtctgcg gaaagagctg gaccagatac ctcaactccc
    10981 agagccaaat cttctttata gagctcattg cgataggtcg caaattcata aagtcgttca
    11041 atatcctttg catcaaagag cccagcttga ttcggcggaa tattaagcaa gagtggagtt
    11101 cctcgcccta ctgagtgaaa gtagatttcg accaactcct cgagagactt aggatcctga
    11161 tcctcatggt agaaccagcc tggacggatg gaaacatctg cctctccgat tgaaaaaatc
    11221 gtgcccgagg gatccccgtg ctgaagatag ttcagctctg cgtctgttcc tagtttatca
    11281 ggattcacct tttgccacag tggatcacct gcataccctc gttcattgcc aatccatcgg
    11341 atactggtgc cttctgttga aaaaatcaaa caatcgccct gcaagtcacg aatggtttca
    11401 aaccattttt caaattcata attaaccttt tgcgcgccct ctcctctggc accatccatc
    11461 caaacctcag cgaacttacc agcattccca tagttaggat ttgataagat ttccttcaac
    11521 tgagccagat aataggcatt gtagtccgct tctcggtcca catgatagag gggactatgg
    11581 gcatcccacg gtgacaggta gacccccata tccatatcaa actctgtggc agcttgggat
    11641 acttcaagga gcaagtcgcc ctttcctctc ctccaaggac tgaccttaac cgaataatct
    11701 gtgtgagctg tcggataaag gacaaagcca tcgtggtgct tgaccaccaa aatcaacttt
    11761 ttgaagcccg tttccttgag cacacgaacc cactcacgcg catccaactg actcgggtta
    11821 aagcgctcag gatcctcctg tccagtcccc cattcttggt cataaaaggt attaggaccg
    11881 aagtggataa aagctgctag ttcatctccc agataagcta gctgagtctg acttggtaac
    11941 ggtccatgcg gtttgatttt cttcatcgtt atatatctcc ttctttagca acttctcttg
    12001 ttcacaaggt tatccacagg ttgtggataa taaaaaatga tctaaccgcc agctctttcc
    12061 aactccaact ggtaggctca ggatttttct cctcaatatt ccctcttcaa acagctctgt
    12121 catatggttc tgctaacacc tctcagaatg ctactctcca taattattct caggcttctt
    12181 tcaggtcatt gtgtgaagac cattcactat ccagactttt ccacagattg tgaataagtg
    12241 attattctaa actatcacct cgtcgactat aacaaaaaat aaaaagaggg tcaataagat
    12301 aattatctct tcctaaatac tcagaaaaga ttctataatt tgtacaattg aacaagaaat
    12361 gcttctccaa aatctatctt caaaagaatg ttgcatcttt ttatcctttc acacaaacat
    12421 ttctctttat acagatccaa gtgataacca gatgataatt ggacactttt tggtcatttg
    12481 tatatttttt gaaaaatttt ttaaaaaaat tttatatcct ttttatagaa gtttatgcat
    12541 ttgtatctat gtattctatc ctatgttatg tataataaca taaaattgtg ctaaacatca
    12601 taatttatat tattttccga gaaattatag ccattgacat tacctaggaa ttgcgttata
    12661 acatacatgt aagcggtacc caaaatggtg ccaagtcaaa atttttaagg aggaaaatac
    12721 atgtcttcac atccaattca ggtcttctca gaaattggga aactgaaaaa agttatgttg
    12781 caccgtccag gcaaggagtt agaaaacttg ttgccggact atcttgaaag gcttcttttt
    12841 gatgatattc ctttcttgga agatgctcaa aaagaacatg atgcatttgc ccaagctctt
    12901 cgcgatgaag gaattgaggt tctataccta gaacaactcg ctgctgaatc attgacctct
    12961 ccagaaatcc gcgatcaatt tatcgaggaa tacttagacg aagccaacat ccgtgatcgt
    13021 caaaccaagg ttgctattcg tgaattgctt cacggcatca aggacaacca agaattggtt
    13081 gaaaaaacaa tggctgggat tcaaaaagtt gaattgccag aaattcctga cgaagctaaa
    13141 gatctaactg acttagttga atcagattat ccatttgcaa ttgacccgat gccaaacctc
    13201 tatttcactc gcgacccatt tgcaacaatt ggaaacgccg tatcgcttaa ccacatgttt
    13261 gcagacactc gtaaccgtga aacactctac ggtaagtata tcttcaaata ccacccagtc
    13321 tatggcggaa aagtggattt ggtctacaac cgtgaagaag atacgcgtat cgaaggtgga
    13381 gacgagctag ttctttctaa agacgtcctt gcagtaggta tctctcaacg tacagacgca
    13441 gcttctatcg aaaaactttt ggtcaacatc ttcaagaaaa atgttggctt caagaaagtt
    13501 ttggcctttg aatttgctaa caaccgtaaa ttcatgcact tggatactgt cttcactatg
    13561 gtagactatg acaagttcac tattcaccca gaaatcgaag gcgaccttca cgtttactca
    13621 gttacttacg aaaacgaaaa acttaaaatc gttgaagaga aaggtgactt agctgaactt
    13681 cttgctcaaa accttggtgt agaaaaagtt catttgattc gttgcggtgg tggcaatatc
    13741 gtagcagctg cgcgtgaaca atggaacgac ggttctaaca ctttgaccat cgcacctggt
    13801 gtggtagttg tttatgaccg caataccgtg accaataaga ttttggaaga atacgggctt
    13861 cgcttgatta agattcgcgg aagtgaattg gttcggggcc gtggtggacc tcgttgtatg
    13921 tctatgccat ttgaacgtga agaagtgtaa tcgctgttcg atattcgtca atagaaaatg
    13981 taaaaaatag aaagaggaaa taataaaatg acaaattcag tattccaagg acgcagcttc
    14041 ttagcagaaa aagactttac ccgtacagag ttagaatacc ttattggtct ttcagctcac
    14101 ttgaaagatt tgaaaaaacg caatattcaa caccactacc ttgctggcaa gaatatcgct
    14161 ctcctatttg aaaaaacatc tactcgtact cgtgcagcct ttacaactgc ggctatcgac
    14221 cttggtgctc acccagaata cctcggagca aatgatattc agttgggtaa aaaagaatct
    14281 actgaagata ctgctaaagt attgggacgt atgtttgacg ggattgaatt ccgcggattc
    14341 agccaacgta tggttgaaga attggcagaa ttctcaggcg ttccagtatg gaacggtcta
    14401 actgacgaat ggcacccaac tcaaatgctc gctgactact tgactgttca agaaaacttc
    14461 ggtcgcttgg aaggcttgac attggtatac tgtggtgatg gacgtaacaa cgttgccaac
    14521 agcttgctcg taacaggtgc tatccttggt gtcaatgttc acatcttctc accaaaagaa
    14581 ctcttcccag aaaaagaaat cgttgaattg gcagaaggat ttgctaaaga aagtggcgca
    14641 catgttctca tcactgaaga tgctgatgaa gcagttaaag atgcagacgt tctttacaca
    14701 gacgtttggg tatcaatggg tgaagaagac aaattcgcag aacgtgtagc tcttcttaaa
    14761 ccttaccaag tcaatatgga cttagttaaa aaagcaggca atgaaaactt gatcttccta
    14821 cactgcttgc cagcattcca cgatactcac actgtttatg gtaaagacgt tgctgaaaaa
    14881 tttggtgtag aagaaatgga agtaacagac gaagtcttcc gcagcaagta cgctcgccac
    14941 ttcgatcaag cagaaaaccg tatgcacact atcaaagctg ttatggctgc tacacttggt
    15001 aacctttata ttcctaaagt ataattttag ataataaacc gtctaccaac agctatgagg
    15061 gctgcgacta atagctttag tccggtcctc ttttatgtaa tggtaatcta ttatttctta
    15121 taaaatatgt gaaaaatcat taaattgaaa tctaaacgca ttctattgag tgtgataaag
    15181 gagaatttat ggcaaatcgt aaaattgtag tagctttggg aggaaatgcg attctttctt
    15241 ctgacccatc agcaaaggct caacaagaag ctttagttga aacagctaag catcttgtaa
    15301 aattgattaa aaatggagat gatttgatta tcactcacgg taatggacct caagttggga
    15361 atctcttgct ccaacatttg gcatcagact ctgaaaagaa ccctgccttc ccactcgact
    15421 cacttgtcgc tatgacagaa ggtagcatcg gtttctggtt gaaaaatgct ttgcaaaatg
    15481 ctctcttgga tgaaggcatc gaaaaaaatg ttgcctctgt tgtaacgcaa gttgtcgtag
    15541 ataaaaatga tccggctttt gttaacttga gtaaaccaat cggtcctttc tattcagaag
    15601 aagaagcaaa agcagaagcc gaaaagagcg gagcgacttt caaggaagat gctggccgtg
    15661 gctggcgtaa ggtcgttgcc tcaccaaaac ctgttgacat caaagaaatt gaaaccatcc
    15721 gtactctttt aaataatggt caagtcgtcg tagctgcagg tggtggcggt attcccgtcg
    15781 tcaaagaaaa caatggacat ttgactggtg tcgaagcggt tattgataaa gacttcgctt
    15841 cccaacgttt ggcagaatta gttgatgcag acctcttcat cgttttgaca ggtgtagatt
    15901 atgtatttgt taactacaac aagccaaacc aggaaaaatt ggaacatgtg aatgttgccc
    15961 agctggaaga atatatcaaa caagatcagt ttgcaccagg tagcatgctt ccaaaagtag
    16021 aagcagctat cgcttttgtc aatggtcgtc cagaaggaaa agcagttatt acttcccttg
    16081 aaaatctagg cgccttgatt gaatctgaaa gcggaacaat tattgaaaaa ggataagttg
    16141 ttttactaat aagatgtatt ctatttctag tatctttata tcaaattaga aattattctt
    16201 gaaaacatgt acaatatttc aaaagatatt agttttttag actttaatat ggtaaaacaa
    16261 atataaatag aaagcgtttt cttgaatgtt tatttaagaa agtagttggt tttttacact
    16321 ttgttagaca tcaggaggaa aaacaaatga gtgaaaaagc taaaaaaggg tttaagatgc
    16381 cttcatctta caccgtatta ttgataatca ttgctattat ggcagtgcta acttggttta
    16441 tccctgcggg ggcctttata gaaggtattt acgagactca gcctcaaaat ccacaaggga
    16501 tttgggatgt cctcatggca ccgattcggg ctatgctagg tactcatcca gaggaaggtt
    16561 cgctcattaa agaaacgagc gcagcgattg atgtagcctt cttcatcctt atggttgggg
    16621 gtttccttgg cattgtcaac aaaactggtg ctcttgacgt agggattgcc tctatcgtga
    16681 agaagtataa gggccgcgaa aaaatgttaa ttttggtact gatgcctttg tttgccctcg
    16741 gtggtacaac ttatggtatg ggggaagaaa caatggcctt ctatccactc cttgtgccag
    16801 ttatgatggc cgttggtttt gatagcctga ctggtgttgc aattattttg ctcggttctc
    16861 aaatcggctg tttggcatct actctgaatc catttgcgac aggtattgct tcagcgactg
    16921 cgggagttgg tacaggggac ggtatcgtac ttcgtctgat cttctgggtt accttgactg
    16981 ctcttagtac ttggtttgtt taccgttatg cggataagat tcaaaaagat ccgactaagt
    17041 cactggttta tagtactcgc aaagaagatt tgaaacactt taacgtagaa gaatcttcat
    17101 ctgtagaatc tacacttagc agcaaacaaa aatcagttct cttcttattt gtgttgacat
    17161 tcatcttgat ggtattgagc ttcattccat ggacagacct tggcgttacc atttttgatg
    17221 actttaatgc ttggttgact ggtcttccag ttattggtaa tattgtcggt tcatctactt
    17281 ctgcactagg tacttggtac ttcccagaag gcgcaatgct ctttgccttt atgggtatcc
    17341 tgattggtgt tatttatggt cttaaagaag ataagattat ctcttccttc atgaatggtg
    17401 ctgctgactt gctcagtgtt gccttgatcg tagcgattgc tcgtggtatt caagttatca
    17461 tgaacgacgg tatgattacc gatacaatcc tcaactgggg taaagaaggc ttgagcggtc
    17521 tatcttcaca agtctttatc gttgtaactt atatcttcta tctacctatg tcattcttga
    17581 tcccatcttc atctggtctt gccagcgcaa ctatgggtat catggctcca cttggagaat
    17641 ttgtaaatgt ccgtcctagc ttgattatca ctgcttacca atctgcttca ggtgtcttga
    17701 acttgattgc accaacatct ggtattgtga tgggagctct tgcacttgga cgtatcaaca
    17761 ttggtacttg gtggaaattc atgggcaaac tcgtagtcgc tattattgta gtgaccatcg
    17821 cccttcttct ccttggaacc ttccttccat tcctataaaa tagtgagtga ggtgattcca
    17881 tgaaaataga tataacaaat caagttaaag atgaatttct tatatcatta aaaaccttga
    17941 tttcctatcc ttcagtactc aatgaaggag aaaatggaac accttttgga caagcaatcc
    18001 aagatgtcct agaaaaaact ttagagattt gtcgagacat aggtttcact acctatcttg
    18061 accctaaagg ttattacgga tatgcagaaa tcggtcaggg agcagagctt ctggccattc
    18121 tctgtcattt ggatgttgtt ccatcaggtg atgaagcaga ttggcagaca ccgccatttg
    18181 aagcaactat caaagacggc tgggtattcg gacgtggtgt ccaagatgat aaaggccctt
    18241 cgctcgcagc tctctatgca gtaaaaagct tgctggacca aggtattcag ttcaaaaagc
    18301 gcgtacgctt tatctttggt accgatgagg aaaccctctg gcgctgcatg gcacgctaca
    18361 ataccatcga agaacaggcc agcatgggct ttgcacctga ctcatctttt cctctgacct
    18421 atgctgaaaa agggcttcta caggtcaaac ttcatggccc tggatcggat caactagagc
    18481 ttgaagtagg aggcgccttt aacgttgtac cagacaaggc caactaccaa ggtcccctct
    18541 atgaacaggt ttgtaacggt ctcaaagaag ctggttatga ttaccaaacc actgaacaaa
    18601 ccgtaacggt tctcggagtg ccaaagcatg ctaaggatgc tagtcaaggt atcaatgctg
    18661 tcatccgact agctaccatt cttgctcctc tccaagaaca ccctgctctc agctttcttg
    18721 caacacaagc aggtcaagac ggcacaggaa gacaaatctt tggtgatata gcagatgaac
    18781 cttctggtca cctatccttt aatgtcgcag gtctcatgat caatcataaa cgttctgaaa
    18841 tccatattga cattcggact cctgtcttag ctgacaagga agaactagta gagttgctta
    18901 caagatgtgc acaaaactac caactccgct acgaagagtt tgactatcta gcgcctctat
    18961 acgtcgcaaa agacagtaaa ctcgttagca cactgatgca aatctaccaa gaaaagactg
    19021 gcgataacag tcctgctatt tcatccggtg gtgccacttt tgctcgcacc atgccaaatt
    19081 gtgtagcctt cggcgcctta ttcccaggag cgaagcagac agaacatcag gcaaatgaat
    19141 gtgccgttct agaagatttg taccgtgcta tggatattta tgccgaagcc gtctatcgac
    19201 ttgcaactta atcaggcaac tgtttctacc aaagaaaatc gaccgattaa tgaactgcac
    19261 cccaaaagtt agacagaata aatctaactt t
//
LOCUS       DBEJHE010000034        17734 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC4 isolate 671759
            SAMN38261586-rid24793303.denovo.34, whole genome shotgun sequence.
ACCESSION   DBEJHE010000034 DBEJHE010000000
VERSION     DBEJHE010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261586
            Sequence Read Archive: SRR26833752
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 17734)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17734)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576136.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576136.1
            Genome Coverage       :: 109x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 19:48:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,067
            CDSs (total)                      :: 2,029
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 131
            CDSs (without protein)            :: 131
            Pseudo Genes (ambiguous residues) :: 0 of 131
            Pseudo Genes (frameshifted)       :: 64 of 131
            Pseudo Genes (incomplete)         :: 59 of 131
            Pseudo Genes (internal stop)      :: 46 of 131
            Pseudo Genes (multiple problems)  :: 32 of 131
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17734
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261586-rid24793303.denovo.34"
                     /strain="GPSC4"
                     /isolate="671759"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(265..1200)
                     /gene="birA"
                     /locus_tag="ACL3EZ_001677"
     CDS             complement(265..1200)
                     /gene="birA"
                     /locus_tag="ACL3EZ_001677"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     ligase/biotin operon repressor BirA"
                     /protein_id="HGR0393215.1"
                     /translation="MKSYQAVYQILSKETDYISGEKIAEKLSLSRTSIWKAIKRLEQE
                     GIEIDSIKNRGYKLMNGDLILPEILEENLPIKVSFKPETKSTQLDAKEAIDLGHEANT
                     LYLASYQTAGRGRFQRSFYSPQGGIYMTLHLKPNLPYDKLPSYTLLVAGAVYKAIKNL
                     TLIDVDIKWVNDIYLNNHKIGGILTEAMTSVETGLVTDIIIGVGINFTIKDFPQELKE
                     KAASLFKATAPITRNELIIEIWRAFFETPAEELLYLYKKQSFILGKEVTFTLQQKDYK
                     GLAKDISENGKLLVQCDNGKEIWLNSGEISLNSWK"
     gene            complement(1197..2057)
                     /locus_tag="ACL3EZ_001678"
     CDS             complement(1197..2057)
                     /locus_tag="ACL3EZ_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000959966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HGR0393216.1"
                     /translation="MLVFSEYQTGTIDLALSFYGYEECTPNYSFGPAIRDTYVLHYIT
                     KGQGKFHYKDKIVDLKEGDFFLLKPEELTFYQADSKEPWAYYWLGITGGKSPDYFALS
                     QISDQSYLIQSETCHTQTTAKLISDIVRFAQITKSSELAQLHIMGQLHELMFHLGTIA
                     PNQKKKNISSTHQLYLECKRLIDSHYPQSLTIQDLAKELSVHRSYLSSVFKEFNTLSP
                     KEYLLYVRMHRARQLLENTQESIKVIAYSVGFSDPLHFSKAYKQYFNQTPSHTRKEYS
                     QYQLVRKATL"
     gene            2165..4327
                     /locus_tag="ACL3EZ_001679"
     CDS             2165..4327
                     /locus_tag="ACL3EZ_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000538915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HGR0393217.1"
                     /translation="MGVRIENNLFYVESKNLSLIIENRNGYLLLKHLGKTIKNYKGSN
                     SVYERDHAFSGNPTATNRTFSLDTQRQIFGQHGLGDFRKPTIQVQHSVTEVTDFRFVE
                     AKILKGQNGPQGLPSPHSMDDTETLVLMLEDSKAQLSLTLYYTTFNNDATITSYSKLD
                     NNSNQEVVIHKDFSFMADFPAADYEIATLQGAYAREKTVRRQQVEQGIFSISSNRGAS
                     GHAQTPALLLCEQGVTEDAGNVFAIQLMYSGNFEAFVQKNQLNEVRVAIGINPENFSW
                     KLAPEEYFETPVALVTHSDQGLTGISHESQNFVLKHIMLSEFSKKERPILINNWEATY
                     FDFQREKLLELADEAKKVGIELFVLDDGWFGNRFDDNRALGDWVVNEEKLGGSLESLI
                     SAIHERGLQFGLWLEPEMISVDSDLYRQHPDWAIQVPDYEHTYSRNQLVLNLANPQVV
                     EYLKSVLDQLLSYHEIDYIKWDMNRNITKLGNGLTYLETQMQSHQYMLGLYELVSYLT
                     EKHSHILFESCSGGGGRNDLGMIRYFPQVWASDNTDAIARLPIQYGSSYLYPTISMGA
                     HVSAVPNHQMGRMTPLETRGHVAMMGNLGYELDLTNLSDEEKATIANQVNLYKELRPV
                     VQLGQQYRLINPDTASNEAAVQFNYGNQTIVTYVRVLSVVETMETTLKLKDLDEEGLY
                     KLQENGEVYSGAELMYAGLTVILSQGDFLSRQYIFRKL"
     gene            4419..5678
                     /locus_tag="ACL3EZ_001680"
     CDS             4419..5678
                     /locus_tag="ACL3EZ_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HGR0393218.1"
                     /translation="MEWYKKIGLLATTGLALFGLGACSNYGKSADGTVTIEYFNQKKE
                     MTKTLEEITRDFEKENPKIKVKVVNVPNAGEVLKTRVLAGDVPDVVNIYPQSIELQEW
                     AKAGVFEDLSNKDYLKRVKNAYAEKYAVNEKVYNVPFTANAYGIYYNKDKFEELGLKV
                     PETWDEFEQLVKDIVAKGQTSFGIAGADAWTLNGYNQLAFATATGGGKEANQYLRYSQ
                     PNAIKLSDPIMKDDIKVMDILRINGSKQKNWEGAGYTDVIGAFARGDVLMTPNGSWAI
                     TAINEQKPNFKIGTFMIPGKEKGQSLTVGAGDLAWSISATTKHPKEANAFVEYMTRPE
                     VMQKYYDVDGSPTAIEGVKQAGEDSPLAGMTEYAFTDRHLVWLQQYWTSEADFHTLTM
                     NYVLTGDKQGMVNDLNAFFNPMKADVD"
     gene            5692..6558
                     /locus_tag="ACL3EZ_001681"
     CDS             5692..6558
                     /locus_tag="ACL3EZ_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGR0393219.1"
                     /translation="MKKVLQKYWAWAFVVIPLLLQAIFFYVPMFQGAFYSFTNWTGLT
                     YNYKFVGLNNFKLLFMDPKFMNAIGFTAIITIAMVVGEIALGIFIARVLNSKIKGQTF
                     FRAWFFFPAVLSGLTVALIFKQVFNYGLPAIGNALHIEFLQTSLLGTKWGAIFAAVFV
                     LLWQGVAMPIIIFLAGLQSIPTEITEAARIDGATSKQVFWNIELPYLLPSVSMVFILA
                     LKGGLTAFDQVFAMTGGGPNNATTSLGLLVYNYAFKNNQFGYANAIAVILFLLIVVIS
                     IIQLRVSKKFEI"
     gene            6572..7405
                     /locus_tag="ACL3EZ_001682"
     CDS             6572..7405
                     /locus_tag="ACL3EZ_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGR0393220.1"
                     /translation="MKQDERKALIGKYILLILGSVLILVPLLATLFSSFKPTKDIVDN
                     FFGFPTNFTWDNFSRLLADGIGGYYWNSVVITVLSLLAVMIFIPMAAYSIARNMSKRK
                     VFTIMYTLLILGIFVPFQVIMIPITVMMSKLGLANTFGLILLYLTYAIPQTLFLYVGY
                     IKISIPESLDEAAEIDGANQFTTYFRIIFPMMKPMHATTMIINALWFWNDFMLPLLVL
                     NRDSKMWTLPLFQYNYAGQYFNDYGPSFASYVVGIISITIVYLFFQRHIISGMSNGAV
                     K"
     gene            7412..7579
                     /locus_tag="ACL3EZ_001683"
     CDS             7412..7579
                     /locus_tag="ACL3EZ_001683"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0393221.1"
                     /translation="MKIKEQTRKLAAGCSKHCFEVVDETDEVSNHTYGKVKLTWFEEI
                     FEEYKKSSWNL"
     gene            7763..9205
                     /gene="gtfA"
                     /locus_tag="ACL3EZ_001684"
     CDS             7763..9205
                     /gene="gtfA"
                     /locus_tag="ACL3EZ_001684"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004645 - 1,4-alpha-oligoglucan
                     phosphorylase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HGR0393222.1"
                     /translation="MPIQNKTMLITYSDSLGNNLKDLYDNLEEHFGDAIGGVHLLPFF
                     PSTGDRGFAPVDYDEVDSAFGDWEDVKRLGEKYYLMFDFMINHISRQSKYYKDYQEKH
                     EASEFKALFLNWDKFWPENRPTQSDVDLIYKRKDRAPKQEIVFEDGSVEHLWNTFGEE
                     QIDLDVTKEVTMEFIRKTIQHLASNGCDLIRLDAFAYAVKKLDTNDFFVEPDIWDLLD
                     KVRDIAAEYGTELLPEIHEHYSIQFKIADHDYYVYDFALPMVTLYTLYSSRTERLAKW
                     LKMSPMKQFTTLDTHDGIGVVDVKDILTDEEIDYASNELYKVGANVKRKYSSAEYNNL
                     DIYQINSTYYSALGDDDVKYFLARLIQAFAPGIPQVYYVGLLAGKNDLKLLEETKEGR
                     NINRHYYSNEEIAKEVQRPVVKALLNLFSFRNRSEAFDLEGTTEIETPTAHSIVIKRQ
                     NKDKSVTAVVEIDLQNQTYRVIENGVEVSF"
     gene            9343..10536
                     /locus_tag="ACL3EZ_001685"
     CDS             9343..10536
                     /locus_tag="ACL3EZ_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008293041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008754 - O antigen ligase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HGR0393223.1"
                     /translation="MKSIGFIEKLKGLSSKELILLGIILSIFLPFYLFVVVLCLYIIS
                     LIFTGDMKSILQKMGEHPMLLLFLSYSTVISILAQNWMGLVASVGMFLFTIFFLHYQS
                     ILSHKFFRLILQFVLFGSVLSAAFASLEHFQIVKKFNYAFLSPNMQVWHQNRAEVTFF
                     NPNYYGIICCFCIMIAFYLFTTTKLNWLKVFCVIAGFVNLFGLNFTQNRTAFPAIIAG
                     AIIYLFTTIKNWKAFWLSIGVFAIGLSFLFSSDLGVRMGTLDSSMEERISIWDAGMAL
                     FKQNPFWGEGPLTYMHSYPRIHAPYHEHAHSLYIDTILSYGIVGTILLVLSSVAPVRL
                     MMDMSQESGKRPIIGLYLSFLTVVAVHGIFDLALFWIQSGFIFLLVMCSIPLEHRMLV
                     SDMTD"
     gene            11222..13201
                     /locus_tag="ACL3EZ_001686"
     CDS             11222..13201
                     /locus_tag="ACL3EZ_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000742236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HGR0393224.1"
                     /translation="MKKNRVFATAGLVLLAAGVLAACSSSKSSDSSAPKAYGYVYTAD
                     PETLDYLISSKNSTTVVTSNGIDGLFTNDNYGNLAPAVAEDWEVSKDGLTYTYKIRKG
                     VKWFTSDGEEYAEVTAKDFVNGLKHAADKKSEAMYLAENSVKGLADYLSGTSTDFSTV
                     GVKAVDDYTLQYTLNQPEPFWNSKLTYSIFWPLNEEFETSKGSDFAKPTDPTSLLYNG
                     PFLLKGLTAKSSVEFVKNEQYWDKENVHLDTINLAYYDGSDQESLERNFTSGAYSYAR
                     LYPTSSNYSKVAEEYKDNIYYTQSGSGIAGLGVNIDRQSYNYTSKTTDSEKVATKKAL
                     LNKDFRQALNFALDRSAYSAQINGKDGAALAVRNLFVKPDFVSAGEKTFGDLVAAQLP
                     AYGDEWKGVNLADGQDGLFNADKAKAEFAKAKKALEADGVQFPIHLDVPVDQASKNYI
                     SRIQSFKQSVETVLGVENVVVDIQQMTSDEFLNITYYAANASSEDWDVSGGVSWGPDY
                     QDPSTYLDILKTTSSETTKTYLGFDNPNSPSVVQVGLKEYDKLVDEAAKETSDLNVRY
                     EKYAAAQAWLTDSSLFIPAMASSGAAPVLSRIVPFTGASAQTGSKGSDVYFKYLKLQD
                     KAVTKEEYEKAREKWLKEKAESNEKAQKELASHVK"
     gene            13268..14764
                     /locus_tag="ACL3EZ_001687"
     CDS             13268..14764
                     /locus_tag="ACL3EZ_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0393225.1"
                     /translation="MKKYIFMRVLRSLVSIFLVTTLTYTIIYTLVPRKLIFKQDPNYN
                     KIATTADKRDNYENTVFERMGYIEYYDTKELQEKASSMDSSVTVEANATNKAIYEKYI
                     NQLGHGWTLGEFTESGQFYATREIPIFERVFHFYANLIDIDHTNKIQDPENPDLKRYL
                     RFENDPAIGWSLVGSGTKHKYLLYFNSQFPFVHQNFVNLNLGDSYPTYANTPVLQVIT
                     QGQGQTKTAQVQFPTGKKTSSVNIYSRTYKSPSQADSREVASYGKDDPYTATESNYQY
                     PSMIVSSAITGLIGLVLAYALAVPLGSAMARFKNTWIDSLSTGALTFLLALPTIALVY
                     IVRLIGSSISLPDSFPILGAGDWRSYVLPAVILGLLGAPGTAIWIRRYMIDLQSQDFV
                     RFARAKGLSEKEISNKHIFKNAMVPLVSGIPGAIIGVIGGATLTETVFAFPGMGKMLI
                     DSVKASNNSMVVGLVFIFTCISIFSRLLGDIWMTIIDPRIKLTEKGGK"
     gene            14764..15690
                     /gene="oppC"
                     /locus_tag="ACL3EZ_001688"
     CDS             14764..15690
                     /gene="oppC"
                     /locus_tag="ACL3EZ_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter permease OppC"
                     /protein_id="HGR0393226.1"
                     /translation="MSTIDKEKFQFVKRDDFASETIDAPAYSYWKSVFKQFMKKKSTV
                     VMLGILVAIILISFIYPMFSKFDFNDVSKVNDFSVRYIKPNAEHWFGTDSNGKSLFDG
                     VWFGARNSILISVIATVINLVIGVFVGGIWGISKSVDRVMMEVYNVISNIPPLLIVIV
                     LTYSIGAGFWNLIFAMSVTTWIGIAFMIRVQILRYRDLEYNLASRTLGTPTLKIVAKN
                     IMPQLVSVIVTTMTQMLPSFISYEAFLSFFGLGLPITVPSLGRLISDYSQNVTTNAYL
                     FWIPLTTLVLVSLSLFVVGQNLADASDPRTHR"
     gene            15699..16766
                     /locus_tag="ACL3EZ_001689"
     CDS             15699..16766
                     /locus_tag="ACL3EZ_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0393227.1"
                     /translation="MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALV
                     GESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDLTALSSHKDWEQIRGAKIATIFQ
                     DPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
                     SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITH
                     DLGVVASIADKVAVMYAGEIVEYGTVEEVFYDPRHPYTWSLLSSLPQLADDKGELYSI
                     PGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSKTHWAKTWLLHEDAPKVEKP
                     AVIANLHDKIREKMGFAHLAD"
     gene            16777..17703
                     /locus_tag="ACL3EZ_001690"
     CDS             16777..17703
                     /locus_tag="ACL3EZ_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGR0393228.1"
                     /translation="MSEKLVEIKDLEISFGEGSKKFVAVKNANFFINKGETFSLVGES
                     GSGKTTIGRAIIGLNDTSNGDIIFDGQKINGKKSREQAAELIRRIQMIFQDPAASLNE
                     RATVDYIISEGLYNHRLFKDEEERKEKVQNIIREVGLLAEHLTRYPHEFSGGQRQRIG
                     IARALVMQPDFVIADEPISALDVSVRAQVLNLLKKFQKELGLTYLFIAHDLSVVRFIS
                     DRIAVIYKGVIVEVAETEELFNNPIHPYTQALLSAVPIPDPILERKKVLKVYDPSQHD
                     YETDKPSMVEIRPGHYVWANQAELARYQKGLN"
BASE COUNT         5206 a         3163 c         3724 g         5641 t
ORIGIN      
        1 gcgtcgtagt ccagtttggc gatgatttct ttgtgtgaat ccctattgac gacatctata
       61 atttggatat ttgtgtcttt gatatcgagt agttttgtga taaaatgtaa ttgttccata
      121 tgaatctttc taatgagttg tttgatcgct tttcattata gatcttatgg gacttttttt
      181 ctacacaaaa ataggctcca taatatccat aggggattta cccactacaa atattataga
      241 gccttatatt ataattgtgt tattttactt ccaactattg agagaaattt cgccactatt
      301 tagccagatt tcttttccgt tatcacattg aactaaaagt tttccatttt ctgagatgtc
      361 tttagcaagt cccttgtagt ctttttgctg tagtgtgaaa gtgacttctt ttcctagaat
      421 gaatgactgt tttttgtata ggtataatag ctcttctgct ggtgtttcga agaaagcacg
      481 ccagatttct atgatcaatt cattccttgt tataggagct gtagctttaa ataagctggc
      541 agctttttct tttaattcct gagggaagtc tttaatagtg aaattgatac ctactccaat
      601 aatgatatct gtgactaagc cagtttctac agaggtcatt gcttcagtaa ggattcctcc
      661 aattttatga ttgtttagat agatatcatt gacccatttt atgtcgacat ctattaaagt
      721 taggttctta atagctttgt agacagctcc agctacaagt agtgtgtagg atggtaattt
      781 gtcatagggg agatttggtt taagatggag tgtcatataa ataccacctt gtggtgagta
      841 gaaggaacgt tgaaaacgtc ctcggcctgc tgtttgatag gaagctagat agagggtatt
      901 tgcttcatgg cctaaatcaa ttgcttcttt tgcatctagt tgtgttgatt ttgtttcggg
      961 tttaaagctg actttaattg gaagattttc ttctagaatc tctggaagaa taaggtcacc
     1021 attcattagt ttatatcctc tatttttgat actatcaatt tcaatgcctt cttgttctag
     1081 tcgcttgata gctttccaaa ttgatgttcg gcttagggat agtttttctg cgattttttc
     1141 tccgctgata tagtcggttt ctttagatag gatttggtag acagcttggt aggatttcat
     1201 aatgttgcct ttctcactag ttggtattga gagtattctt ttcttgtatg acttggagtc
     1261 tgattaaagt attgtttata agctttcgaa aaatggagtg gatctgaaaa acctaccgag
     1321 tatgcaatta ccttgatgga ctcttgggta ttttcgagaa gttgtctagc tcggtgcatt
     1381 cgaacgtaga gtaggtattc tttgggtgat aaggtattaa attctttgaa tacgcttgat
     1441 aagtagcttc tgtgaacgga tagttctttt gctaaatctt gaattgtaag tgattgagga
     1501 tagtggctat caattaatcg tttgcattca agatagagtt ggtgggttga tgaaatattc
     1561 ttttttttct gattgggagc aatagttccc agatgaaaca tcagttcatg aagttgtccc
     1621 atgatatgga gttgagctaa ttcacttgat tttgtaatct gagcgaagcg gacaatgtct
     1681 gagatgagtt ttgcagtagt ctgggtatga caagtttcag attggatgag ataggattga
     1741 tcagaaattt gagaaagagc aaaataatca ggggatttcc ctccagtgat tcctaaccag
     1801 tagtaggccc aaggttcttt actatctgct tgataaaagg ttagttcctc tggttttaat
     1861 agaaagaaat ctccttcttt taaatcaaca attttatcct tgtaatgaaa ttttccttgt
     1921 cctttagtaa tgtaatgtag gacgtatgta tcacgaatgg ctggaccaaa agagtaatta
     1981 ggtgtgcatt cctcatatcc ataaaagctt agggcaaggt cgattgttcc agtctggtat
     2041 tctgaaaaaa ctaacatgtg ctacctccta cctaacattt taccatattc ttgagacatt
     2101 tttctatttt ggaaagcgat ttcaggtgat aaaatataat caataaagtg atgaggtgaa
     2161 gtaaatggga gttaggatag agaataatct attttatgtt gagagtaaaa atctaagttt
     2221 gattattgaa aatcgaaatg gctacttact tttgaaacat ttaggaaaga ctattaagaa
     2281 ctataaaggt tccaatagtg tttatgaacg agaccatgcc ttttcaggaa atccaacggc
     2341 tactaatcga acctttagtt tagatactca gcgacagatt tttggacaac atggcttagg
     2401 agattttagg aaaccaacta tacaggttca gcatagtgta actgaagtaa cagactttcg
     2461 atttgtagaa gcaaagattt taaaaggtca gaatggtcca cagggcttac cttctccaca
     2521 tagcatggac gatacagaga ctcttgtctt aatgttagaa gattctaagg ctcaacttag
     2581 tctgactttg tattatacta cttttaataa tgatgcgact attactagct acagtaaatt
     2641 agataataat agtaatcagg aagttgtcat ccataaagat ttttctttta tggctgattt
     2701 tccagctgca gattatgaaa tagcaactct gcagggtgct tatgctcgtg aaaagactgt
     2761 tagacgtcaa caggtagaac aaggaatctt ttcgattagt tcaaaccgag gtgcttctgg
     2821 tcatgctcaa acaccagctc ttctactatg cgaacaagga gtcacagagg atgctgggaa
     2881 tgtgtttgct attcaactaa tgtatagtgg caactttgaa gcttttgttc aaaaaaatca
     2941 attgaatgaa gttcgggtgg ctattggcat taatccagaa aacttttctt ggaagttagc
     3001 ccctgaggaa tactttgaaa caccggtagc tttagtgact cattcagatc agggattaac
     3061 tggtattagt catgaaagtc agaattttgt actgaagcac attatgctaa gtgaattttc
     3121 taaaaaagaa cgtccaattc taatcaataa ctgggaagct acttactttg actttcagag
     3181 agaaaaactg ttagagttag cagatgaagc taagaaagtt ggcattgaac tttttgtatt
     3241 agatgatggt tggtttggca atcgttttga tgataatcgt gctttaggtg attgggttgt
     3301 taatgaggaa aaactgggtg gaagtctaga aagtctgatt tcagctatcc atgaaagagg
     3361 tttgcagttt ggactttggt tagaacccga aatgatttct gtagatagtg atttgtatcg
     3421 tcaacatcct gactgggcta ttcaggttcc tgattatgag catacttatt ctcggaatca
     3481 attagtactt aatcttgcca atcctcaggt agtagaatac ttgaaaagtg tcttagatca
     3541 actcctatct tatcatgaga ttgattacat taaatgggat atgaaccgca atatcactaa
     3601 gctagggaat ggattaactt atctagagac acagatgcaa tctcatcagt acatgctggg
     3661 gctttacgaa ctcgtttctt atctgacaga gaagcacagc catattctct ttgagtcctg
     3721 ctctggtggt ggtggacgaa atgatcttgg tatgatacgc tatttcccac aagtctgggc
     3781 tagtgataat actgatgcca ttgcacgttt accaattcaa tacggttcat cctatctcta
     3841 tccaaccatt tctatggggg ctcatgtgtc agcagtaccg aatcatcaga tgggacgaat
     3901 gacaccatta gaaacacgtg gccatgtagc aatgatggga aatttgggct atgagcttga
     3961 tttgacaaat ttatcagatg aagagaaagc tacgattgct aatcaggtga acttgtataa
     4021 agaattacga ccagtagttc agttaggaca gcagtataga ctaattaatc ctgatactgc
     4081 atccaatgaa gcagctgtac aatttaatta cggaaatcaa acgattgtaa cctacgttcg
     4141 cgttttatct gttgtagaga ccatggaaac aactttaaaa ttaaaagatt tggatgaaga
     4201 gggactatat aaattacagg aaaatggcga agtttactca ggtgcagaac taatgtatgc
     4261 gggcttaact gttatcttat cccaaggaga ttttttgagt agacagtata tttttagaaa
     4321 actatgatat gtactgaccc caaaagttag atttattctg tctaactttt ggggtgcagt
     4381 tcaataaggg tgtataaatt tataaaggag gctttctaat ggaatggtat aaaaaaatcg
     4441 gacttcttgc aactacaggt ttagctttgt ttgggctcgg cgcttgctcc aactatggta
     4501 aatctgcgga tggcacagtg accatcgagt atttcaacca gaaaaaagaa atgaccaaaa
     4561 ccttggaaga aatcactcgt gattttgaga aggaaaaccc taagatcaag gtcaaagtcg
     4621 tcaatgtacc aaatgctggt gaagtattga agacacgcgt tctcgcagga gatgtgcctg
     4681 atgtggtcaa tatttaccca cagtccatcg aactgcaaga atgggcaaaa gcaggtgttt
     4741 ttgaagattt gagcaacaaa gactacctga aacgcgtgaa aaatgcctac gctgaaaaat
     4801 atgctgtaaa cgaaaaagtt tataacgttc cttttacagc taatgcttat ggaatttact
     4861 acaacaaaga taaattcgaa gaactgggct tgaaggttcc tgaaacctgg gatgaatttg
     4921 aacagttagt caaagatatc gttgctaaag gacaaacatc atttggaatt gcaggtgcag
     4981 atgcttggac actcaatggt tacaatcaat tagcctttgc gacagcaaca ggtggaggaa
     5041 aagaagcaaa tcaatacctt cgttattctc aaccaaatgc cattaaattg tcggatccga
     5101 ttatgaaaga tgatatcaag gtcatggaca tccttcgcat caatggctct aagcaaaaga
     5161 actgggaagg tgctggctat accgatgtta tcggagcctt cgcacgtggg gatgtcctca
     5221 tgacaccaaa tgggtcttgg gcgatcacag cgattaatga acaaaaaccg aactttaaga
     5281 ttggaacctt catgattcca ggaaaagaaa aaggacaaag cttaaccgtt ggtgcgggag
     5341 acttggcatg gtctatctca gccaccacca aacatccaaa agaagccaat gcctttgtgg
     5401 aatatatgac ccgtccagaa gtcatgcaaa aatactacga tgtggacgga tctccaacag
     5461 cgatcgaagg ggtcaaacaa gcaggagaag attcaccgct tgctggtatg accgaatatg
     5521 cctttacgga tcgtcacttg gtctggttgc aacaatactg gaccagtgaa gcagacttcc
     5581 ataccttgac catgaactat gtcttgaccg gtgataaaca aggcatggtc aatgatttga
     5641 atgccttctt taacccgatg aaagcggatg tggattagga gtagagagac tatgaaaaaa
     5701 gtattacaaa aatattgggc atgggctttt gtggtcatcc ccctcttgtt acaagcaatt
     5761 ttcttctatg tgccgatgtt tcaaggagcc ttttacagtt ttaccaactg gacaggattg
     5821 acttacaact acaaatttgt cggcttaaac aactttaagc tcctcttcat ggatccaaaa
     5881 ttcatgaatg cgattggctt taccgcaatc attacgattg ccatggtggt tggtgagatt
     5941 gcactcggga tcttcattgc gcgtgtcttg aactctaaaa tcaaaggcca aaccttcttc
     6001 cgtgcttggt tcttcttccc agctgtttta tctggtttga cagtggcttt gatcttcaag
     6061 caagtcttca actacggtct tccagcgatt gggaatgccc ttcatattga atttctccaa
     6121 accagtcttt tagggactaa gtggggagca atctttgcgg ctgtctttgt ccttctttgg
     6181 caaggggtgg ctatgcccat catcatcttc ctagctggtt tgcaatctat tccaactgag
     6241 attacagagg cagcaaggat tgatggtgcg actagcaagc aagttttctg gaacattgaa
     6301 ttgccttact tgctaccaag tgtctctatg gtctttatcc tagccctaaa aggtgggctg
     6361 actgcctttg accaagtctt tgccatgacc ggtggtggtc caaacaatgc cacaacctca
     6421 cttgggctct tggtttataa ctatgccttt aaaaacaacc aattcggtta tgccaatgcc
     6481 attgccgtaa tcttgttcct cttaattgta gtgatttcga tcatccaatt gagagtatct
     6541 aagaaatttg aaatttaaga ggagaagcat gatgaaacaa gatgaaagaa aagccctgat
     6601 tggcaaatac attctattga ttctaggatc ggttctgatt ttagtgccgc tccttgctac
     6661 cctctttagt tccttcaaac ccactaagga tattgtagat aatttctttg gctttccaac
     6721 caacttcaca tgggacaact ttagccgtct cttagctgat gggattggag gctattattg
     6781 gaactctgtc gtcatcactg tcttgtcttt acttgcagta atgatcttta tccctatggc
     6841 agcctactcc atcgctcgca atatgagtaa aagaaaagtc tttaccatca tgtataccct
     6901 cttaatcctc ggaatcttcg tacctttcca agtcatcatg attccgatta cggttatgat
     6961 gagtaaactc ggtttggcta atacctttgg tttgatcttg ctctacttga cctatgcgat
     7021 tccacagacc ctctttctct atgttggcta tatcaaaatc tcgattccag aaagtctgga
     7081 tgaagcagca gagatcgatg gggctaatca atttacaacc tatttccgca tcatcttccc
     7141 aatgatgaaa ccgatgcatg cgacaaccat gatcatcaat gccctttggt tctggaatga
     7201 cttcatgttg ccactccttg tcttgaaccg ggattccaaa atgtggactc tgcctttgtt
     7261 ccaatacaac tacgcaggcc aatatttcaa cgactacgga ccaagctttg cctcttacgt
     7321 ggtcggcatt atcagtatca ccattgtcta tctcttcttc caacgccata tcatttcagg
     7381 aatgagcaac ggggcagtga agtaatactc aatgaaaatc aaagagcaaa ctaggaagct
     7441 agccgcaggt tgctcaaaac actgttttga ggttgtggat gaaactgacg aagtcagtaa
     7501 ccatacctac ggtaaggtga agctgacgtg gtttgaagag attttcgaag agtataagaa
     7561 gagctcatgg aatctatagt ctttgacaca gaggaagagt tcagcttgtt gataattcta
     7621 tgtagaaaac aagaaagtag tactttgttt atcacagtct atattagtac gagtttgatg
     7681 ataaatagag atttaaaatg aatttgattt acgaagccag atcatatgag acttggcttc
     7741 aattagaaaa aggagagtaa tgatgccgat tcaaaataaa accatgttga ttacctattc
     7801 tgatagcctt ggaaataatc ttaaagactt atatgataat ttggaagagc attttggaga
     7861 tgctattgga ggagttcacc ttttaccatt tttcccatca acaggtgatc gtggatttgc
     7921 gccagttgac tacgacgaag tggactcagc ttttggtgat tgggaggatg ttaagcgttt
     7981 aggtgagaaa tattatctta tgtttgattt tatgattaat catatttctc gtcaatccaa
     8041 gtattataag gactatcaag aaaaacatga agccagtgaa tttaaagctc tctttttaaa
     8101 ctgggataag ttttggccag aaaaccgtcc gacacagtct gatgtagatt taatttacaa
     8161 gcgtaaggat cgtgcaccaa agcaagagat tgtgtttgaa gatggttcag tggaacattt
     8221 gtggaatacc tttggtgagg agcagattga tcttgatgtg accaaagaag taactatgga
     8281 atttatccgt aagaccattc agcacttggc aagtaatggg tgtgatttga ttcgtctaga
     8341 tgcctttgct tatgcagtga agaaattgga tactaatgat ttctttgtgg aaccagatat
     8401 ttgggattta ttggacaaag ttcgagatat cgctgctgag tatgggacag agcttttacc
     8461 tgagattcat gaacactatt cgattcagtt taaaatagca gaccatgatt actatgttta
     8521 tgattttgct cttccaatgg tgacacttta tactctttac agttccagaa cagagcgttt
     8581 ggctaagtgg ttaaagatga gcccgatgaa gcaatttacg acgctagata cccatgatgg
     8641 gattggagta gtagatgtca aggatatcct gaccgatgag gagattgact atgcttcaaa
     8701 tgaactctat aaggttggag ccaatgtcaa acgtaagtac tctagtgccg agtataacaa
     8761 cttagatatc taccaaatca attcaaccta ctattcagcg cttggagatg atgatgtcaa
     8821 gtattttctc gctcgtctaa ttcaagcttt tgccccaggt attcctcagg tttactatgt
     8881 gggtctatta gcaggcaaga atgacttgaa attattagaa gaaactaaag aaggtcgaaa
     8941 tattaatcgt cattactata gcaacgagga aatagcaaaa gaagtgcaac gacctgttgt
     9001 gaaggccctt ctcaatctat tttctttccg taaccgttca gaagcctttg atctagaagg
     9061 gactactgag atagagacac caacagctca cagcattgta atcaaacgtc aaaataaaga
     9121 taagtccgta acagcagtag tagaaattga tttgcaaaat cagacttatc gggtaattga
     9181 gaatggagtt gaagtatcat tttgaagcct tgatatggtg gataaaatag ggtttttatt
     9241 ttggaaaacg tttcctttgt tttcaaattg ctaaaaaagt ggtacaatat aggatagctt
     9301 actattatct gaatcagctg atttggagag aaaggattca ttttgaaatc aataggcttt
     9361 attgaaaagc tgaaggggtt gtctagtaaa gagctgattt tattgggaat tatcctaagt
     9421 atctttttac ccttttatct ttttgtagtt gtactctgtt tatatattat cagtttgatt
     9481 tttacaggag acatgaaaag tattcttcag aaaatggggg agcatccgat gctgcttctt
     9541 tttcttagct atagtactgt tatatccatt cttgcacaaa attggatggg tcttgtggct
     9601 tcagtaggaa tgtttctatt tactattttc tttttgcact atcagtcgat tttatcccat
     9661 aaattctttc gattgatttt gcagttcgtc ttgtttggta gtgtcttgtc agctgctttt
     9721 gccagtttag aacatttcca aattgtgaag aaatttaact atgcttttct ttcacccaat
     9781 atgcaggtgt ggcatcagaa ccgggcagaa gtgaccttct ttaatcctaa ttattatgga
     9841 attatttgtt gtttctgtat tatgattgct ttctatctgt ttacaacgac caagttgaat
     9901 tggttgaaag tattctgtgt gattgcaggc tttgttaatc tctttggttt gaactttact
     9961 caaaatcgaa ctgcctttcc tgctattatc gctggagcaa ttatctatct ctttacgact
    10021 attaaaaact ggaaggcctt ttggcttagt attggggtct tcgcgattgg tttgagtttc
    10081 ctcttttcta gtgatttggg agttcgaatg ggtactttag actcttctat ggaagaacgc
    10141 atttctatct gggatgctgg gatggccttg tttaagcaaa atcctttttg gggtgaaggg
    10201 ccattgacct atatgcactc ttatcctcgg atacatgctc cttatcatga acatgcccac
    10261 agtctttata ttgatacgat tctgagttac ggaattgtgg gtaccatttt attagttttg
    10321 tcttctgttg ctcctgttcg cttgatgatg gatatgagtc aggagtcggg gaaacgtccg
    10381 attatcggcc tttatctatc tttccttaca gtggttgctg tgcacggaat ttttgacttg
    10441 gctctcttct ggattcagtc aggctttatt ttcttgctag ttatgtgcag tattccattg
    10501 gagcatcgaa tgttggtatc ggacatgacg gattaagttt tataagtttg aaatcttcta
    10561 ccttgggtag gagatttttt tatacgatgg gcatgtcgtg catctgaggt gtaagtcctc
    10621 tgtagggatc cactaccggt gaatacaata gcgctcccca agcctgacta tcgtgaggta
    10681 gcggattaaa atggtctggg gatagatcgt tttaagtctg acgcaggaaa taagaattgt
    10741 cagagaaagc aatagtgaaa tcgtaggcta tgaatagaaa cgtgatagcg aggagcatat
    10801 agtggacaag gtagcgagaa attttaaagt ataaaagata gtcttaatct atatgtgtaa
    10861 atcacgaaag taattgaatt cggaataagg ttggtgtgaa aagacatagt aaactgaatc
    10921 ttgaatacta gaatgatact tctacaatat tgttataatt taatttgaat tccaaaatca
    10981 cattgttccg tccgtatttc attttactgt atgtcttcct aagctccaaa atttctgtgt
    11041 caaatttcct attttcactg tagtctttga cacttcgaac gacaatttga atcatatatt
    11101 caaaaaaaat gaaaaatttg tgccaacaag cctaaatatt ctgaaaattt gtttgatttt
    11161 taatggataa tgtgatataa tggttgtcaa tctataattc acataaacag aggagtagaa
    11221 aatgaaaaaa aatcgtgtat ttgctacagc aggtcttgtt ttattagcag caggtgtact
    11281 tgcagcatgc agttcttcaa aatcatctga ttcatcagcc cctaaagctt atggctatgt
    11341 ttatacagca gacccagaaa ccttggacta cctgatttca agtaaaaata gtacaacagt
    11401 agtgacttca aatgggattg atggtttatt cactaacgat aattacggta atcttgctcc
    11461 tgcagttgca gaggattggg aagtctctaa ggatggtttg acctacactt ataagattcg
    11521 taaaggggtt aaatggttta cctctgatgg agaagaatat gcagaggtga cggctaaaga
    11581 tttcgtgaac ggtttaaaac acgcagcaga taaaaaatca gaagctatgt atttagctga
    11641 aaattcggtt aaaggcttgg cagattatct atcaggaact tcaacagatt tttcaacagt
    11701 tggtgtcaag gcggttgatg attatacgtt acaatacact ttgaaccagc ctgaaccgtt
    11761 ctggaactct aagttgacct attctatttt ctggcctctg aatgaagaat tcgaaacatc
    11821 aaaaggaagc gattttgcta aaccaacaga tccgacatcc ttgctttata atggtccatt
    11881 cttgttgaaa gggttgactg caaaatcttc tgtagagttt gtaaaaaatg agcaatattg
    11941 ggataaagaa aatgtccacc tagatactat caatctagct tactatgatg gatcagatca
    12001 ggagtcgcta gagcgtaact tcactagtgg agcttatagt tatgcccgtc tttaccctac
    12061 cagctccaac tattctaagg ttgcagaaga atacaaggac aatatctatt acacacaatc
    12121 aggctctggg attgctggtc tgggtgtgaa tattgatcgc caaagttaca actatacttc
    12181 taaaactaca gattcagaga aagtagctac taagaaggca ttgcttaaca aagatttccg
    12241 tcaagccttg aattttgctc ttgatcgctc agcttactca gctcaaatca atggtaaaga
    12301 tggagcagct ttagcagttc gtaatttatt tgtaaaacca gactttgttt cagctggtga
    12361 gaagaccttt ggtgatttag tcgctgctca acttcctgct tatggtgatg agtggaaagg
    12421 tgtgaattta gctgatgggc aggatggttt attcaatgct gacaaggcca aggcagagtt
    12481 tgcgaaagct aagaaagctt tagaagcaga cggcgttcag tttcctattc atctggacgt
    12541 tccagtagac caagcatcaa aaaactatat atctcgtatt cagtccttta aacaatctgt
    12601 agaaacagtt cttggtgttg aaaatgtcgt tgttgatatt caacaaatga caagtgatga
    12661 attccttaat attacttact atgctgccaa tgcttcatct gaggattggg atgtatcggg
    12721 aggagtttca tgggggccag actatcaaga cccatctact tacctggata ttttaaaaac
    12781 aactagcagt gaaactacaa aaacatattt aggatttgat aatccaaata gcccttcagt
    12841 agttcaagtt ggtttgaaag aatacgataa attagttgat gaagctgcca aagagacaag
    12901 cgacttgaat gtccgttatg aaaaatatgc agcggctcaa gcatggttga cagatagttc
    12961 actctttatt cctgctatgg cttcttctgg tgcagcacca gtgctttcac gaattgttcc
    13021 atttactgga gcttctgcgc aaacaggctc taaggggtca gatgtttact tcaaatattt
    13081 gaaattacaa gataaagcgg tgactaagga agagtatgaa aaagctcgtg aaaaatggtt
    13141 gaaagaaaaa gctgaatcaa atgagaaagc tcaaaaagaa ttggcaagtc atgtgaagta
    13201 aataatttct aatagaactt tctctccatg aggagaaggt tcttttggga tttttaaagg
    13261 aaataatatg aaaaaatata tttttatgcg tgttttgcgg tcattggttt cgattttctt
    13321 agtaacgact ttgacctaca cgattatcta taccttggtt cctcgaaaat tgattttcaa
    13381 gcaggatcct aactataata aaattgcgac aacggctgat aaacgtgata actatgaaaa
    13441 tactgtgttt gagcgtatgg gctacattga gtattacgat actaaagagt tgcaagaaaa
    13501 ggcaagtagc atggattctt ctgtaacagt agaagcaaat gcgaccaata aagctattta
    13561 tgaaaagtac atcaatcaat taggtcatgg ttggactttg ggagaattta ctgaaagtgg
    13621 tcaattctat gctactcgtg aaattccaat ttttgaacgt gtttttcact tctatgctaa
    13681 cttgattgac attgaccata caaataaaat ccaagaccct gaaaatccag acttgaaacg
    13741 ctaccttcgt tttgaaaacg atccagctat cggatggtca ttggtcggtt caggaactaa
    13801 acataaatat ctcttgtact ttaacagtca gttcccattt gttcatcaaa actttgtgaa
    13861 cttgaattta ggtgactctt acccaaccta tgctaataca ccagttcttc aggttattac
    13921 tcaaggtcaa ggacaaacca aaactgccca agttcagttc ccaacaggta agaaaacgtc
    13981 ttctgtaaat atttactcaa gaacctacaa gtcacctagt caggctgact ctcgtgaagt
    14041 agctagctat gggaaagatg atccttatac agcgactgaa agtaattacc aatatccatc
    14101 tatgattgtc agctctgcta ttactggttt gattggtttg gttcttgcct atgctcttgc
    14161 cgtgccactt ggttcagcca tggctcgttt caagaacact tggattgata gcctctcaac
    14221 aggggctttg accttcttgc ttgctcttcc aacgattgcc ttggtttaca tcgttcgatt
    14281 gattggatca tctatttccc ttccagattc attccctatc ttgggagctg gagattggcg
    14341 ttcttacgtt ttaccagcag tcatccttgg tttgttgggt gctcctggta cagccatttg
    14401 gattcgtcgt tacatgattg acttgcaatc tcaagacttt gttcgtttcg ctcgtgcaaa
    14461 aggtttgtct gaaaaagaaa tttcaaacaa acacatcttt aaaaatgcca tggttccgct
    14521 ggtttcagga attcctggtg ccattattgg ggttatcggt ggtgcaaccc ttactgaaac
    14581 agtcttcgcc ttcccaggta tgggtaaaat gttgattgac tctgtaaaag catctaataa
    14641 ctctatggtc gttggtcttg tcttcatctt tacatgtatt tctatcttct cacgtctttt
    14701 gggagatatt tggatgacta ttattgaccc acgtattaaa ttgactgaga aaggaggcaa
    14761 ataatgtcta caatcgataa agaaaaattt cagtttgtaa aacgtgacga ttttgcctct
    14821 gaaactattg atgcgccagc atattcttac tggaaatcag tgtttaaaca atttatgaag
    14881 aaaaaatcaa ctgtagtcat gttgggaatc ttggtagcca tcattttgat aagtttcatc
    14941 tacccaatgt tttctaagtt tgatttcaat gatgtcagca aggtaaacga ctttagtgtt
    15001 cgttatatca agccaaatgc ggagcattgg ttcggtactg acagtaacgg taaatcgctc
    15061 tttgacggtg tctggttcgg agctcgtaac tccatcctca tttctgtgat tgcgacagtg
    15121 attaacttgg ttatcggtgt ttttgtcggt ggtatttggg gtatttcaaa atcagttgac
    15181 cgtgtcatga tggaagttta caacgtcatc tcaaacatcc cacctctttt gattgttatt
    15241 gtcttgactt actcaatcgg agctggattc tggaatctga tttttgccat gagcgtaaca
    15301 acatggattg gtattgcctt catgatccgt gtgcaaatct tgcgctatcg tgacttggaa
    15361 tacaacttgg cgtcacgtac tttgggaaca ccaaccttga agattgttgc caaaaatatc
    15421 atgcctcaat tggtatctgt tattgtgaca accatgactc aaatgcttcc aagctttatc
    15481 tcatacgaag ccttcttgtc tttcttcggt cttggattac cgattacagt gccaagtttg
    15541 ggtcgtttga tttcggatta ttcacaaaac gtaacaacca atgcttactt gttctggatt
    15601 ccattgacaa cccttgtctt ggtatccttg tcccttttcg tagttggtca aaacttagcg
    15661 gatgctagtg atccacgtac acatagatag gagtagaaat gacaaaagaa aaaaatgtaa
    15721 ttttgactgc tcgcgatatt gtcgtggaat ttgacgttcg tgacaaagta ttgacagcca
    15781 ttcgcggcgt ttcccttgaa ctagtcgaag gagaagtatt agccttggta ggtgagtcag
    15841 gatcaggtaa atctgttttg acaaagacct tcacaggtat gctcgaagaa aatggtcgca
    15901 ttgcccaagg tagtattgac taccgtggtc aggacttgac agctttatct tctcacaagg
    15961 attgggaaca aattcgtggt gctaagattg cgactatctt ccaggaccca atgactagtt
    16021 tggaccccat taaaacaatt ggtagtcaga ttacagaagt tattgtaaaa caccaaggaa
    16081 aaacagctaa agaagcgaaa gaattggcca ttgactacat gaataaggtt ggcattccag
    16141 acgcagatag acgttttaat gaatacccat tccaatattc tggaggaatg cgtcaacgta
    16201 tcgttattgc gattgccctt gcctgccgac ctgatgtctt gatctgtgat gagccaacaa
    16261 ctgccttgga tgtaactatt caagctcaga ttattgattt gctaaaatct ttacaaaacg
    16321 agtatcattt cacaacaatc tttattaccc acgaccttgg tgtggtggca agtattgcgg
    16381 ataaggtagc ggttatgtat gcaggagaaa tcgttgagta tggaacggtt gaggaagtct
    16441 tctatgaccc tcgccatcca tatacatgga gtctcttgtc tagcttgcct cagcttgctg
    16501 atgataaagg ggaactttac tcaatcccag gaacacctcc gtcactttat actgacctga
    16561 aaggggatgc ttttgctttg cgttctgact acgcaatgca gattgacttc gaacaaaaag
    16621 ctcctcaatt ctcagtatca aagacacatt gggctaaaac ttggcttctt catgaggatg
    16681 ctccaaaagt agaaaaacca gctgtgattg caaatctcca tgataagatc cgtgaaaaaa
    16741 tgggatttgc ccatctggct gactaggagg aaggaaatgt ctgaaaaatt agtagaaatc
    16801 aaagatttag aaatttcctt cggtgaagga agtaagaagt ttgtcgcggt taaaaatgct
    16861 aacttcttta tcaacaaggg agaaactttc tcgcttgtag gtgagtccgg tagtgggaaa
    16921 acaactattg gtcgtgctat catcggtcta aatgatacaa gtaatggaga tatcattttt
    16981 gatggtcaaa agattaatgg taagaaatcg cgtgaacaag ctgcggaatt gattcgtcga
    17041 atccagatga ttttccaaga ccctgccgca agtttgaatg aacgtgcgac tgttgattat
    17101 attatttctg aaggtcttta caatcaccgt ttatttaagg atgaagaaga acgtaaagag
    17161 aaagttcaaa atattatccg tgaagtaggt cttcttgctg agcacttgac tcgttaccct
    17221 catgaattct caggcggtca acgtcaacgt atcggtattg cccgtgcctt ggtcatgcaa
    17281 ccagactttg ttattgcaga tgagccaatt tcagccttgg acgtttctgt acgtgcccaa
    17341 gtcttgaact tgctcaaaaa attccaaaaa gagctcggcc tgacctatct cttcatcgcc
    17401 catgacttgt cggttgttcg ctttatttca gatcgtatcg cagttattta caagggtgtt
    17461 attgtagagg ttgcagaaac agaagaattg tttaacaatc caattcaccc atatactcaa
    17521 gccttgcttt cagcggtacc aatcccagat ccaatcttgg aacgtaagaa ggtcttgaag
    17581 gtttacgacc caagtcaaca cgactatgag actgataagc catctatggt agaaatccgt
    17641 ccaggtcact atgtttgggc gaaccaagcc gaattggcac gttatcaaaa aggactaaac
    17701 tagtaatggt tttataattt ccatgtcaat tttt
//
LOCUS       DBEJHE010000035        17144 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC4 isolate 671759
            SAMN38261586-rid24793303.denovo.35, whole genome shotgun sequence.
ACCESSION   DBEJHE010000035 DBEJHE010000000
VERSION     DBEJHE010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261586
            Sequence Read Archive: SRR26833752
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 17144)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17144)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576136.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576136.1
            Genome Coverage       :: 109x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 19:48:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,067
            CDSs (total)                      :: 2,029
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 131
            CDSs (without protein)            :: 131
            Pseudo Genes (ambiguous residues) :: 0 of 131
            Pseudo Genes (frameshifted)       :: 64 of 131
            Pseudo Genes (incomplete)         :: 59 of 131
            Pseudo Genes (internal stop)      :: 46 of 131
            Pseudo Genes (multiple problems)  :: 32 of 131
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17144
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261586-rid24793303.denovo.35"
                     /strain="GPSC4"
                     /isolate="671759"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            91..588
                     /locus_tag="ACL3EZ_001691"
                     /pseudo
     CDS             91..588
                     /locus_tag="ACL3EZ_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234238.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
     gene            745..1170
                     /gene="lacA"
                     /locus_tag="ACL3EZ_001692"
     CDS             745..1170
                     /gene="lacA"
                     /locus_tag="ACL3EZ_001692"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050044 - galactose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HGR0393229.1"
                     /translation="MSIVIGADAAGLRLKEVVKDFLEKENFHLVDVTAEGQDFVDVTL
                     AVAAEVNKEEQNLGIVIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNSRMIT
                     MGAQLVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMG"
     gene            1201..1716
                     /gene="lacB"
                     /locus_tag="ACL3EZ_001693"
     CDS             1201..1716
                     /gene="lacB"
                     /locus_tag="ACL3EZ_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HGR0393230.1"
                     /translation="MRIAIGCDHIVTDEKMAVSEFLKSKGYEVIDFGTYDHTRTHYPI
                     FGKKVGEAVTSGQADLGVCICGTGVGINNAVNKVPGVRSALVRDMTTALYAKEQLNAN
                     VIGFGGKITGELLMCDIIEAFIHAEYKPTEENKKLIAKIEHVESHNAQQTDANFFTEF
                     LEKWDRGEYHD"
     gene            1727..2656
                     /locus_tag="ACL3EZ_001694"
     CDS             1727..2656
                     /locus_tag="ACL3EZ_001694"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009024 - tagatose-6-phosphate kinase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HGR0393231.1"
                     /translation="MILTVTMNPSIDISYPLDELKIDTVNRVVDVTKTAGGKGLNVTR
                     VLSEFGDSVLATGLVGGKLGEFLVEHIDNQVKKDFFSIQGETRNCIAILHGDNQTEVL
                     EKGPEVLEQEGQDFLEHFKKLLESVEVVAISGSLPAGLPVDYYASLVELANQAGKPVV
                     LDCSGAALQAVLESPHKPTVIKPNNEELSQLLGREVSEDLDELKEVLQEPLFAGIEWI
                     IVSLGANGTFAKHGDTFYKVDIPRIQVVNPVGSGDSTVAGISSGLLHKESDAELLIKA
                     NVLGMLNAQEKMTGHVNMANYQVLYDQLIVKEV"
     gene            2658..3638
                     /gene="lacD"
                     /locus_tag="ACL3EZ_001695"
     CDS             2658..3638
                     /gene="lacD"
                     /locus_tag="ACL3EZ_001695"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009025 - tagatose-bisphosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HGR0393232.1"
                     /translation="MALTEQKRVRLEKLSDENGIISALAFDQRGALKRLMAQHQTEEP
                     TVAQMEELKVLVADELTKYASSMLLDPEYGLPATKALDEKAGLLLAYEKTGYDTTSTK
                     RLPDCLDVWSAKRIKEEGADAVKFLLYYDVDSSDELNQEKQAYIERIGSECVAEDIPF
                     FLEILAYDEKIADAGSVEYAKVKPHKVIGAMKVFSDPRFNIDVLKVEVPVNIKYVEGF
                     AEGEVVYTREEAAAFFKAQDEATNLPYIYLSAGVSAKLFQDTLVFAHESGANFNGVLC
                     GRATWAGSVEAYIKDGETAAREWLRTTGFENIDELNKVLQTTATSWKERV"
     gene            3872..4708
                     /locus_tag="ACL3EZ_001696"
     CDS             3872..4708
                     /locus_tag="ACL3EZ_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HGR0393233.1"
                     /translation="MYRILNPMNHNVSLVRNDKGEEVIVIGKGIAFGKKKGDLIAENH
                     VEKIFRMKTEESRENFMALLKDVPLDFITVTYEIIDKLSKKYHYPIQEYLYVTLTDHI
                     YCSYQALTQGRYKDSNLPDISAKYPVAFQIANEAFEIYCQKLADHFPEDEIIRIAYHF
                     INAEGENEVELVESIDKRKEILRNVEEVLTDYAIQRTKKNNHFYDRFMIHLNYFLDYL
                     DRSRDDNQSLLDMEDHIKQSYPKAFEIGSKIYDVITQHTGLDLYKSERVYLVLHIQRL
                     LS"
     gene            4744..5061
                     /locus_tag="ACL3EZ_001697"
     CDS             4744..5061
                     /locus_tag="ACL3EZ_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HGR0393234.1"
                     /translation="MNREEVTLLGFEIVAYAGDARSKLLEALKAAEAGDFEKADALVE
                     EAGSCIAEAHHAQTSLLTKEASGEDLAYSVTMMHGQDHLMTTILLKDLMHHLIELYKR
                     GVK"
     gene            5063..6757
                     /locus_tag="ACL3EZ_001698"
     CDS             5063..6757
                     /locus_tag="ACL3EZ_001698"
                     /EC_number="2.7.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0019197 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase complex [Evidence IEA];
                     GO_function: GO:0015155 - lactose transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lactose-specific PTS transporter subunit EIIC"
                     /protein_id="HGR0393235.1"
                     /translation="MDKLIIFIEKGKPFFEKLSRNIYLRAIKDGFISSMPAVLFSSIF
                     ILIAAVPNIFGFKWSDEQLAFILKPYNYSMGILALLVAGTTAKSLTDSVNTRSMEKTN
                     QINYMSTFLAAVVGLLILAADPIEGGFANGLLGTRGLLTAFLAAFITVNIYKVCIKNN
                     VTIRLPEEVPPNIAQVFKDVIPFALSVLSIYGLDLIVRNIFGTNVAESVGKILAPLFS
                     ATDGYIGLAIVFGAYAFFWFVGIHGPSVVEPLIVAISYANIEANVQLVQAGMHADKIL
                     NPVTQTFVVTMGGTGATLVVPFMFMWLCKSKRNRIVGRASVVPTFFGVNEPILFGAPI
                     VLNPIFFIPFVTAPIINVWIMKFFVDVLQMNSFSIILPWTTPAPIGIVMGTALAPLSF
                     VLAITLIIIDTLIYYPFVKVYDHQILEEERKGNSSSELKEKVAANFNTAKADAILEKA
                     GVEAAQNTITKETNVLVLCAGGGTSGLLANALNKAAAEYNVPVKAAAGGYGAHREMLP
                     EFDLVILAPQVASNFEDMKAETDKLGIKLAKTEGAQYIKLTRDGKGALAFVQAQFD"
     gene            6966..8372
                     /gene="lacG"
                     /locus_tag="ACL3EZ_001699"
     CDS             6966..8372
                     /gene="lacG"
                     /locus_tag="ACL3EZ_001699"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033920 - 6-phospho-beta-galactosidase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HGR0393236.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYNRYPVDLKLAEEYGVNGIRISIAWSRIFPTDYGQVNAKGVEFYHNLFAE
                     CHKRHVEPFVTLHHFDTPEALHSNGDFLNRENIEHFVDYAAFCFEEFPEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHARAVKLYKEKGYKGEIGVVHAL
                     PTKYPLDPENPADVRAAELEDIIHNKFILDATYLGRYSAETMEGVNHILSVNGGSLDL
                     REEDFTALEAAKDLNDFLGINYYMSDWMEAFDGETEIIHNGKGEKGSSKYQIKGVGRR
                     VAPDYVPRTDWDWIIYPQGLYDQIMRVKKDYPNYKKIYITENGLGYKDEFVDNTVYDD
                     GRIDYVKQHLEILSDAIADGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFETQERY
                     PKKSAHWYKKVAETQIID"
     gene            8495..8674
                     /locus_tag="ACL3EZ_001700"
     CDS             8495..8674
                     /locus_tag="ACL3EZ_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3884 family protein"
                     /protein_id="HGR0393237.1"
                     /translation="MTSEELKSLGKWYVSTGKEWICHSDDELEEFKNLFLNFINPEEW
                     DTISFDSDFMPFQQS"
     gene            complement(8953..9714)
                     /locus_tag="ACL3EZ_001701"
     CDS             complement(8953..9714)
                     /locus_tag="ACL3EZ_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000917571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HGR0393238.1"
                     /translation="MLKQEKLTKILEIVNSKGTITVKQIMDEIAVSDMTARRYLQELA
                     DKDLLIRVHGGAEKLRTNSLLTNERSNIEKQALQTAEKQEIAHFAGSLVEERETIFIG
                     PGTTLEFFARELPIDNIRVVTNSLPVFLILSERKLTDLILIGGNYRDITGAFVGTLTL
                     QNLSNLQFSKAFVSCNGIQNGALATFSEEEGEAQRIALNNSNKKYLLADHSKFNKFDF
                     YTFYNISNLDTIVSDSKLSDSILFKLSKHIKVIKP"
     gene            complement(10002..10964)
                     /gene="nrdF"
                     /locus_tag="ACL3EZ_001702"
     CDS             complement(10002..10964)
                     /gene="nrdF"
                     /locus_tag="ACL3EZ_001702"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005971 - ribonucleoside-diphosphate
                     reductase complex [Evidence IEA];
                     GO_function: GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA];
                     GO_process: GO:0009263 - deoxyribonucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HGR0393239.1"
                     /translation="METYYKAINWNAIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDW
                     RKLSNKEKDLVGKVFGGLTLLDTMQSETGVQALRADIRTPHEEAVFNNIQFMESVHAK
                     SYSSIFSTLNTKAEIEEIFEWTNTNPYLQKKAEIVNEIYLNGSPLEKKVASVFLETFL
                     FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEEEQEKLK
                     EWMYDLLYTLYENEEGYTESLYDGVGWTEEVKTFLRYNANKALMNMGQDPLFPDSAED
                     VNPIVMNGISTGTSNHDFFSQVGNGYLLGEVEAMQDDDYNYGLD"
     gene            complement(11152..13311)
                     /gene="nrdE"
                     /locus_tag="ACL3EZ_001703"
     CDS             complement(11152..13311)
                     /gene="nrdE"
                     /locus_tag="ACL3EZ_001703"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HGR0393240.1"
                     /translation="MGLKHLEDVTYFRLNNEINRPVNGQIMLHKDKEALDAFFKENVV
                     PNTMVFDSIKDKINYLIEHNYIETAFIKKYRPEFLEELAQFIKDQNFQFKSFMAAYKF
                     YNQYALKTNDGEYYLENMEDRVFFNALYFADGNEAVAIDIANEIIHQRYQPATPSFLN
                     AGRARRGELVSCFLIQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSTKKENADEKVR
                     VKTLSLGVVVPDKFYELARKNEEMYLFSPYSVEKEYGVPFNYIDITEKYDELVANPNI
                     RKTKIKARDLETEISKLQQESGYPYVVNIDTANRANPVDGKIIMSNLCSEILQVQEPS
                     LINDAQEFLQMGTDVSCNLGSTNVVNMMTSPDFGRSIRAMVRALTFVTDSSHIVAVPT
                     IDHGNSQAHTFGLGAMGLHSYLAQQLIEYGSPESVEFTSIYFMLMNYWTLVESNNIAR
                     ERGITFHNFEKSDYANGSYFDKYVTGEFVPTSDRVKELFKNVFIPGVADWTELRDKVQ
                     EDGLYHQNRLAVAPNGSISYINDVSASIHPITQRIEERQEKKIGKIYYPAAGLSTETI
                     PYYTSAYDMDMRKVIDVYAAATEHVDQGLSLTLFMRSDIPKGLYEWKRENKQTTRDLS
                     ILRNYAFNKGIKSIYYVRTFTDDGGEVGANQCESCVI"
     gene            complement(13392..13610)
                     /gene="nrdH"
                     /locus_tag="ACL3EZ_001704"
     CDS             complement(13392..13610)
                     /gene="nrdH"
                     /locus_tag="ACL3EZ_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000259243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HGR0393241.1"
                     /translation="MVTVYSKNNCVQCKMTKRFLDSNNVSYREINLDEQPEYVDQVKE
                     LGFSAAPVIQTPTEVFSGFQPEKLKQLA"
     gene            13961..14224
                     /locus_tag="ACL3EZ_001705"
     CDS             13961..14224
                     /locus_tag="ACL3EZ_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HGR0393242.1"
                     /translation="MASKDFHVVAETGIHARPATLLVQTASKFASDITLEYKGKSVNL
                     KSIMGVMSLGVGQGADVTISAEGADADDAIAAISETMEKEGLA"
     gene            14230..15963
                     /gene="ptsP"
                     /locus_tag="ACL3EZ_001706"
     CDS             14230..15963
                     /gene="ptsP"
                     /locus_tag="ACL3EZ_001706"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008965 - phosphoenolpyruvate-protein
                     phosphotransferase activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HGR0393243.1"
                     /translation="MTEMLKGIAASDGVAVAKAYLLVQPDLSFETITVEDTNAEEARL
                     DAALQASQDELSVIREKAVGTLGEEAAQVFDAHLMVLADPEMISQIKETIRAKKVNAE
                     AGLKEVTDMFITIFEGMEDNPYMQERAADIRDVTKRVLANLLGKKLPNPASINEEVIV
                     IAHDLTPSDTAQLDKNFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNNITEIVKDGD
                     ILAVNGITGEVIINPTDEQAAEFKAAGEAYAKQKAEWALLKDAQTVTADGKHFELAAN
                     IGTPKDVEGVNNNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVR
                     TMDIGGDKELPYFDMPHEMNPFLGFRALRISISETGDAMFRTQIRALLRASVHGQLRI
                     MFPMVALLKEFRAAKAVFDEEKANLLAEGVAVADNIQVGIMIEIPAAAMLADQFAKEV
                     DFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWAGMCGE
                     MAGDQQAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDTAKMEEYANRALTECSTMEEV
                     LELQKEYVNFD"
     gene            16218..>17144
                     /gene="phtA"
                     /locus_tag="ACL3EZ_001707"
     CDS             16218..>17144
                     /gene="phtA"
                     /locus_tag="ACL3EZ_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtA"
                     /protein_id="HGR0393244.1"
                     /translation="MKINKKYLVGSAAALILSVCSYELGLYQARTVKENNRVSYIDGK
                     QATQKTENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIFSEE
                     LLMKDPNYKLKDEDIVNEVKGGYVIKVDGKYYVYLKDAAHADNVRTKEEINRQKQEHS
                     QHREGGTPRNDGAVALARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKN
                     ELSASELAAAEAFLSGRGNLSNSRTYRRQNSDNTSRTNWLPSVSNPGTTNTNTSNNSN
                     TNSQASQSNDIDSLLKQLYKLPLSQRHVESDGL"
BASE COUNT         5416 a         3023 c         3543 g         5162 t
ORIGIN      
        1 cgaaatcatc gtaaacgctt cggattacga atgaatttga ttgctggcat tatcaatcat
       61 gaactaggat tctagttttg caggaagtct aataaagaaa ctagcaaggt caggccttac
      121 tttattggtg gacatccagg atttaattgt cctctacttg atgatgaagt ctatgaagat
      181 tattatctag agtttgagaa agaagagact tgctctgttc cacgtccttt cccagaaaca
      241 ggtatgttgg atttccaaga tagaagtcca tggctagagg gacaaaaaga aatagatctt
      301 agttatgatc ttttcagcaa agatgcagtg actttggatg aattgcaatc tcgaacaatt
      361 gcccttcgtt ctcttaaaca tgatagggga ttgaaagtgc attttgcaga atttccaaac
      421 ctcatcatct ggtcaacttt gaacaaggga cctttcatta cctttgaacc atggtctggc
      481 ttgtcaacat tccttgaaga aggagatcat ttagaagata agaagaatgt ttgtctctta
      541 gaagccaatc aggttgaaga attagggttt gagatagaag ttttataaaa aagtaaaaaa
      601 taaataacaa aaacaaacac aaactgttga cttcttcaaa caatagtagt atattatgtt
      661 tgtgaggact aattgactgt tttttaaaga cagccaatac actgctggaa tccagcatag
      721 aaaaaataaa aaggagtata caatatgtct attgttatcg gtgcagatgc tgcaggtttg
      781 agattgaaag aagttgtgaa agacttctta gaaaaagaaa acttccacct tgtggatgtt
      841 acagctgaag gtcaagactt tgttgatgtg actctcgctg ttgctgcaga agtaaacaaa
      901 gaagaacaaa accttggtat cgtgattgat gcttatggag ctggtccatt tatggttgca
      961 actaagatca aaggaatggt tgctgcagaa gtttctgatg aacgttcagc ttatatgact
     1021 cgtggccaca acaactcacg tatgatcact atgggtgcac aacttgttgg tgatgaattg
     1081 gctaaaaaca tcgctaaagg atttgttaat ggtaaatacg acggtggtcg tcaccaaatc
     1141 cgggttgaca tgttgaacaa aatgggctaa ttagattata gtaagaaagg taagttaaaa
     1201 atgagaattg caattggatg tgaccacatc gtaacagatg aaaaaatggc ggtttcagaa
     1261 tttttgaaat caaaaggata tgaagtcatt gactttggta catatgacca tacacgtact
     1321 cactacccaa tctttggtaa aaaagtaggg gaagctgtaa ctagcggtca agctgatctt
     1381 ggagtatgta tctgtggtac tggtgttggt atcaacaacg ctgtaaataa agttccaggt
     1441 gttcgttctg ccttggttcg tgatatgaca acagcccttt atgctaaaga acaattgaac
     1501 gctaacgtta ttggttttgg tggtaaaatt actggtgaat tgcttatgtg tgatatcatc
     1561 gaagctttca tccatgctga atacaaacca actgaagaaa acaaaaaatt gattgcgaaa
     1621 attgaacatg ttgaaagtca caatgctcaa caaacagacg caaacttctt cactgaattc
     1681 cttgaaaaat gggatcgcgg agaataccac gactaagagg taacctatga ttttaacagt
     1741 tacaatgaac ccatccattg atatttccta tcccttggat gagttgaaga ttgatactgt
     1801 caatcgtgtg gtggatgtaa ccaaaacggc tggtggtaag ggactcaatg ttacccgagt
     1861 actttcagaa tttggcgatt ctgttcttgc tactggttta gtgggtggca aacttggtga
     1921 gtttttggtt gaacatatcg ataatcaagt aaagaaagat ttcttctcaa ttcagggaga
     1981 aactcgtaac tgtatcgcta ttctccacgg agacaaccaa acagaagttc ttgaaaaagg
     2041 tcctgaagta ttggaacagg aaggtcaaga ctttttggaa catttcaaaa aactcttgga
     2101 gtcagttgaa gtagtggcca tctcaggtag tctgccagct ggccttccag ttgattacta
     2161 tgcgagcttg gtagaacttg ctaatcaagc tggcaagcct gtagtcttgg actgctcagg
     2221 tgcagcactt caggctgttc ttgaatcacc ccataaacca acagtcatca aaccaaataa
     2281 tgaagaattg tctcagcttc ttggaagaga agtttctgag gatttggatg aattaaaaga
     2341 agtacttcaa gaacctttgt ttgcagggat tgaatggatt atcgtttcac ttggtgccaa
     2401 cggtactttt gccaaacatg gtgacacttt ctacaaggta gatattccta gaattcaggt
     2461 ggtaaatcct gttggatctg gagactctac tgtggcagga atttcttcag gacttcttca
     2521 caaagaatcg gatgcagaat tactcatcaa ggcaaatgtc cttggtatgc tcaatgctca
     2581 agaaaaaatg actggtcatg tcaacatggc caactatcaa gttctatatg atcaattaat
     2641 agtaaaagag gtataaaatg gctttaacag aacaaaaacg tgtacgctta gaaaaacttt
     2701 ctgatgaaaa tggtatcatc tcagctcttg catttgacca acgtggtgct ttgaaacgcc
     2761 tcatggctca acaccaaaca gaagaaccaa ctgtggccca aatggaagaa cttaaagtct
     2821 tggtagcaga tgaattgact aaatacgctt catctatgct tcttgaccct gagtatggac
     2881 ttccagcaac taaagctctt gatgaaaaag ctggtcttct ccttgcttat gaaaaaacag
     2941 gttatgacac aacaagcaca aaacgcttgc cagactgctt ggatgtctgg tctgcaaaac
     3001 gtattaaaga agaaggtgca gatgcagtta aattcttgct ttactatgat gtagatagct
     3061 cagacgaact caatcaagaa aaacaagcct acatcgaacg catcggttct gagtgtgtgg
     3121 ctgaagatat cccattcttc cttgaaattc ttgcttacga tgaaaaaatt gcggatgcag
     3181 gttctgtaga atacgcgaaa gtaaaaccac acaaagttat cggcgctatg aaagtctttt
     3241 cagacccacg ctttaacatt gatgtcttga aagttgaagt tcctgttaac attaaatatg
     3301 ttgaaggctt cgctgaaggt gaagtagttt atacacgtga agaagcagca gccttcttca
     3361 aagcgcaaga tgaagcaacg aacttgccat acatctactt gagtgctggt gtatcagcta
     3421 aactcttcca agatactctt gtatttgctc atgaatcagg tgcaaacttt aacggagttc
     3481 tttgtggccg tgcaacatgg gctggatcag ttgaagcata catcaaagat ggtgaaacag
     3541 cagctcgcga atggcttcgc acaactggat ttgaaaacat tgatgagctc aacaaagttc
     3601 ttcaaacaac agcaacttca tggaaagaac gtgtgtaaga aagtcctcct agtttaggaa
     3661 catgaatcta aaaaaattta aaaaaagttg tatgtaaagg tttacaaaat aacttacttg
     3721 tgctatactt aaatcacaag ttaatacaag gtgagtgtta ctaagtaata ttaggcatga
     3781 tcacaggtga attagaaatc agctgatttt ctagttcatt tgtggtcatt ttttgtactc
     3841 atataccttt aagatataaa aggaggttga catgtatcga attctaaatc caatgaatca
     3901 caatgtctcg cttgtcagaa atgataaggg agaagaggtg attgtaattg gtaaggggat
     3961 tgcattcgga aagaagaagg gggatttgat tgctgaaaat catgttgaga aaatctttcg
     4021 gatgaagacc gaagagtcca gagaaaactt tatggctctt ctcaaagatg ttccgcttga
     4081 ttttatcaca gtgacctatg aaatcattga taagctatca aagaaatatc attatccgat
     4141 tcaagagtat ctctatgtaa ccttgacaga tcatatttac tgttcttatc aagctctaac
     4201 tcaaggaagg tacaaggata gtaatctgcc agatatttct gctaagtatc ctgtcgcttt
     4261 tcaaatcgca aatgaagctt ttgaaattta ctgtcagaag ctagcagatc attttcctga
     4321 ggacgaaatt attcggattg cttatcattt cattaatgct gaaggtgaaa atgaagtgga
     4381 acttgtggag tcgattgata agaggaaaga aattctcagg aatgttgaag aagttttaac
     4441 ggactatgca attcaacgaa ctaaaaagaa taaccatttc tatgatcgct ttatgatcca
     4501 tttgaattat ttcttggatt atttagacag atctagagat gataaccaat cacttctgga
     4561 tatggaagat catattaaac aatcctatcc aaaagccttc gagattggtt ccaagatcta
     4621 tgatgtgatt acgcaacata cgggtcttga tttgtataaa agtgaacgag tttatctagt
     4681 tctacatatc caacgtttat tgtcataaaa atttatttaa aactatataa ggagaattct
     4741 atcatgaata gagaagaagt aacattgtta ggttttgaaa tcgtagccta tgctggcgat
     4801 gctcgttcaa aactattgga agccttgaag gctgctgaag ctggtgattt tgaaaaagcg
     4861 gacgctctgg tagaggaagc tggtagctgt attgcagagg ctcaccacgc gcaaacaagt
     4921 ctattgacta aggaagcttc tggtgaggac ttagcgtata gtgtgaccat gatgcatggt
     4981 caagatcact tgatgacaac tatcttgtta aaagacctaa tgcaccattt aattgaactt
     5041 tacaagagag gagttaaata aaatggataa gttaataatt tttattgaga aaggaaagcc
     5101 tttctttgag aaattatcga gaaatatata cttaagagcg ataaaagatg gttttatttc
     5161 cagtatgcca gcagtattat tctcaagtat ttttatacta atagctgctg tgcccaatat
     5221 ttttgggttt aaatggtctg atgaacagtt agcttttatt ttgaaacctt acaactactc
     5281 aatggggatt ttagctctct tagtagctgg gacaactgca aaatcgttaa cagattcagt
     5341 taatacacgt agtatggaga aaaccaacca aatcaactac atgtcaactt ttttagcagc
     5401 tgttgttgga ttgttaatac tggcagctga tccaattgaa ggtggatttg ctaatggtct
     5461 tttaggtact agaggattac ttactgcatt tttggcagct tttattacag taaatatcta
     5521 taaagtatgt attaaaaata atgtaaccat tagacttcct gaagaggttc caccaaatat
     5581 tgcacaagtt tttaaagatg ttattccgtt tgccttatct gttctttcaa tatatggatt
     5641 ggatttaatt gttagaaata tttttggtac aaatgtagca gaatctgttg gtaaaatatt
     5701 agcccctcta ttttcagcta ctgatggtta tatcggttta gctattgtat ttggtgctta
     5761 tgctttcttt tggtttgttg gaattcatgg gccatctgtt gtagaacctt taattgtagc
     5821 tatcagttat gcaaatatag aagctaatgt tcagcttgtg caagctggta tgcacgcaga
     5881 taaaatttta aatccagtta ctcaaacttt tgttgtaaca atgggtggta ctggtgcaac
     5941 actagtagtt ccatttatgt ttatgtggtt atgtaaatca aaaagaaata gaattgtcgg
     6001 acgtgcgtct gtagttccta ctttctttgg cgtaaatgaa ccaatcctat ttggtgctcc
     6061 aattgtttta aatcctatct tctttattcc gtttgttact gctcctatta tcaatgtttg
     6121 gattatgaaa ttttttgtag atgttctaca aatgaatagt ttcagtatta ttttaccttg
     6181 gacaacacct gctccaattg gtattgttat gggaacggcg ctggctccat tgtcattcgt
     6241 cttggctata actttaatca ttatcgacac tttaatctat tatccatttg ttaaagttta
     6301 tgaccatcaa attttagaag aagaacggaa aggaaactct tcatctgaat tgaaagaaaa
     6361 agttgctgca aacttcaaca ctgcaaaagc ggatgctatt cttgaaaaag cgggtgtaga
     6421 agcagcacaa aatacaatca ctaaagaaac aaatgtcctc gttctctgtg caggtggagg
     6481 aacaagtggt ctccttgcaa atgctttgaa taaggcagca gcagaataca atgtccctgt
     6541 gaaagcagca gcaggcggct atggtgctca ccgtgaaatg ttaccagagt ttgatcttgt
     6601 tatccttgcc cctcaagttg cttcaaactt tgaagatatg aaagcagaaa cagataagct
     6661 cggtattaaa ctagcgaaaa cagaaggcgc tcaatacatc aaattaactc gtgatggaaa
     6721 aggtgctctt gcattcgtac aagcgcaatt cgattaaggc tagagactct gaaatagtct
     6781 cctatcgtta cggaaatcgc tatggcgaat ttcctattat taattcgtcg gtaaaaagat
     6841 atcgttttta cctcctcatg tcacaattcg gtgacttggt acaagaagtg agatggagaa
     6901 ggatggctca ctgactcctc tcctctcact tttactttat ttaaatcaag aaataggtga
     6961 aaaaaatgac aaaaacactt ccaaaagact ttatttttgg tggcgcaaca gctgcctatc
     7021 aagcagaagg tgctacacat actgatggta aaggaccagt agcgtgggat aaatatcttg
     7081 aagataacta ctggtacact gcagaaccag ccagtgattt ttacaatcga tatccagttg
     7141 acctcaagct agcagaagag tatggtgtca atggtattcg aatttctatt gcttggtcac
     7201 gtattttccc gactgattac ggccaagtaa atgctaaagg tgttgagttt tatcataatt
     7261 tatttgcaga gtgtcacaaa cgtcatgttg agccttttgt aactcttcat cactttgaca
     7321 cgccagaagc tctccactca aatggagact tcttaaaccg tgaaaatatc gaacattttg
     7381 tagactacgc tgccttctgt tttgaagaat ttccagaagt aaactattgg acaaccttta
     7441 atgaaattgg accaatcggt gatggtcaat atttggttgg gaaattccct ccaggtatcc
     7501 agtacgacct tgccaaagtc tttcaatcac accacaatat gatggtgtct catgcacgcg
     7561 cggtaaaatt gtacaaagag aaaggctata aaggggaaat tggtgttgtt cacgccctgc
     7621 caactaaata tcctctagat cctgaaaatc cagcagatgt tcgtgcagct gagttggaag
     7681 atatcatcca caataaattc atcttagacg caacttatct aggtcgctat tcagctgaaa
     7741 ccatggaagg tgtcaaccat atcttatcag tcaatggtgg tagcttggat cttcgtgaag
     7801 aagattttac agcattagaa gctgcaaaag acttgaatga tttcctagga atcaactact
     7861 atatgagtga ctggatggaa gcctttgatg gagaaactga aattatccat aatggtaaag
     7921 gtgaaaaagg aagctctaag tatcaaatca aaggtgttgg tcgtcgtgta gctcctgact
     7981 atgtaccacg cacggattgg gattggatta tctaccctca aggtttgtat gaccaaatca
     8041 tgcgtgtgaa gaaagattat cctaactaca agaagattta catcactgaa aatggtctcg
     8101 gctataaaga tgagttcgtt gataacactg tttacgatga tggtcgtatt gattacgtga
     8161 aacaacactt ggagatcttg tctgatgcga ttgcagatgg agctaatgta aaaggttact
     8221 tcatttggtc attaatggat gtcttctcat ggtcaaacgg ttatgagaaa cgttatggtc
     8281 tcttctacgt agattttgaa actcaagaac gttatcctaa gaaatcagct cactggtaca
     8341 agaaagtagc ggaaactcag attatagact agtagaatta gtcattagat atagaatttt
     8401 agtgagtcaa aaagatgttc aaagatttta tccaatctat ttatgaaaaa aagtttatat
     8461 tataaatttc gaaaaatgct ctcaaatacc gtgtttgacg agtgaagaat tgaaaagtct
     8521 tggaaaatgg tatgtctcga ctggtaaaga atggatttgt cattcagatg atgagctgga
     8581 agaatttaaa aatctatttt taaattttat caatcctgaa gaatgggata ctatctcctt
     8641 tgattcagat tttatgccgt ttcaacaatc gtaaccaatt tctcaaaaaa gttaaatctt
     8701 atatttagta ctctgtaaaa ctcttatcta atcacgttgc ttatactcaa tgaaaatcaa
     8761 agagcaactt taaactagga agcgagtcgc agatttctca atgcatagct ttgaggaatt
     8821 gggcaaaaag tctttgatat agaaaaaagc atagtatcag gtgttgaaac acctgatact
     8881 atgcttttta ttgtgggaag atttactttt tttcttctga aattgagttg ttacccaggc
     8941 tctttcagtt tattaaggct tgatgacttt aatgtgttta gatagcttaa aaaggattga
     9001 atcacttagt ttagaatctg aaacaatagt atcaagattt gatatattat aaaaagtata
     9061 aaaatcaaac ttattgaact tactatgatc tgcgagtaaa tattttttat tagaattatt
     9121 taaagcgatg cgttgagcct ctccctcttc ctcgctaaaa gtagctagag ctccgttttg
     9181 aataccatta cagctaacga aagctttaga aaattggaga ttagagagat tttgtagggt
     9241 caatgtgcca acaaaagcac ctgtaatatc gcgataattt ccacctatca aaatcaaatc
     9301 tgttaatttt cgttcgctta aaatcagaaa aacaggtaga ctgttggtta cgacgcggat
     9361 attgtcaata ggcaactcac gcgcaaaaaa ctctaatgtt gttcctggtc caatgaaaat
     9421 agtttctctt tcttctacta gactgcctgc aaaatgggct atttcttgtt tttctgccgt
     9481 ttggagggct tgtttttcaa tatttgatcg ctcattagtc aaaagggagt tggttcgaag
     9541 tttttcagct ccaccatgca cacgaatcag caaatcttta tcagctaatt cctgtaaata
     9601 gcgccttgca gtcatatctg aaacggctat ttcgtccata atctgtttaa ctgttatggt
     9661 tcctttacta tttactatct ctaaaatttt ggttaatttt tcttgtttga gcatattatc
     9721 acctcgtttc ctactactat cttaccataa acaaactcat cattcaaata caaaaacaac
     9781 aaaatgaaac aaaaacaaaa atatcgaagt ttgttttcaa aactttcgat atttttgttg
     9841 ggttattatt ttgttgtttc tagtttactt tttgatggtt aagagtggtg gagaattata
     9901 ctcaatgaaa atcaaagagc aaactaggaa gctagccgca ggctgtactt gagtacggca
     9961 aggcgaagct gacgtggttt gaatttgatt ttcgaagagt attagtccaa accgtagttg
    10021 tagtcatcat cttgcatggc ttcaacttcg ccaagaaggt aaccatttcc gacttgagag
    10081 aagaagtcat ggttggaagt tcctgttgaa ataccgttca taacgattgg gttgacatct
    10141 tcagctgaat ctgggaaaag tggatcttgt cccatgttca tgagagcttt attggcattg
    10201 tagcgaagga aggttttaac ctcttcagtc caaccaacac cgtcataaag actctctgtg
    10261 tagccttctt cattttcata aagagtatag agtaggtcgt acatccattc tttgagtttt
    10321 tcttgctctt cttcaggtaa ttcattgaaa ccaagttgga atttgtaacc aatgtaggtt
    10381 ccgtgaacag actcgtcacg aataatcaat ttaatgattt ctgcaacgtt ggcaagtttg
    10441 ttgttaccga gatagtagag gggagtgaag aaaccagagt agaagaggaa ggtttcgagg
    10501 aagacgctgg caactttctt ttcaagtggg ctgccgttta ggtagatttc gttgacaatc
    10561 tcagccttct tttgtaggta aggattggta ttggtccatt cgaaaatttc ttcaatctca
    10621 gccttagtat tcaaggtaga aaagattgat gagtaagatt tagcgtggac agattccata
    10681 aattggatgt tattgaaaac agcttcctca tgtggtgtac ggatgtctgc gcgaagggct
    10741 tgaaccccag tttcagattg catagtgtca agaagggtta aaccaccaaa aacttttccg
    10801 accaagtctt tctctttgtt agatagcttt ctccagtcat ccaagtcgtt tgataaggga
    10861 atacgtgtat cgagccaaaa ttgctccgtc agtttttccc aagttgattt gtcgatgaca
    10921 tcttcgatgg cattccagtt aatggctttg tagtaagttt ccatttaaaa tctctttctg
    10981 tgtttagtat tgcgaactca caattatttc tactttacca taattctata ggagtatcgc
    11041 acaaaaagtc ggaagcccga cttttaaaat gttacataaa ttatgttatg acatagtaga
    11101 tttgatttta tcagtgctgc ttagggaaaa atagtgtttc tatgctagaa actaaatcac
    11161 acagctttca cattggttgg cgccgacttc tccaccgtca tctgtaaagg tacggacgta
    11221 gtagatagac ttgattccct tgttaaaggc atagttacga aggatggaca agtcacgtgt
    11281 cgtttgttta ttttccctct tccattcgta aaggcctttt ggaatgtcac tacgcatgaa
    11341 gagggtgagt gaaagtcctt gatccacgtg ttcagtcgca gcagcgtaaa catcgatgac
    11401 tttacgcata tccatatcgt aggcagaagt gtagtaagga atggtttctg tagacaagcc
    11461 agcagcaggg tagtagattt taccaatttt cttttcctga cgttcttcaa tacgttgcgt
    11521 aatcgggtgg atagaagcag aaacatcgtt gatgtagctg atagaaccat ttggcgctac
    11581 agcaaggcga ttttggtggt aaagaccatc ctcttgaacc ttgtcgcgaa gttcagtcca
    11641 atcagcaaca ccagggataa aaacattttt gaagagttct ttaacacggt ctgatgttgg
    11701 aacaaattca ccagttacat acttgtcaaa gtaacttccg ttagcatagt ctgatttttc
    11761 aaagttgtgg aaggtaatac cacgttcacg cgcaatattg tttgactcta ccaaggtcca
    11821 gtagttcata agcataaagt agatgcttgt aaattcaaca gactcaggtg aaccatattc
    11881 aatgagttgt tgggcaaggt agctgtgcag tcccatggca ccgagaccaa aggtgtgggc
    11941 ttggctattt ccatggtcaa tcgttggtac agctacgata tgtgaactat ctgtaacgaa
    12001 agtaagggca cgaaccatag cacggataga acgaccaaaa tcaggtgaag tcatcatgtt
    12061 aaccacgttg gttgaaccca ggttacatga aacatctgtt cccatttgaa ggaattcttg
    12121 agcatcgttg atcaagcttg gttcttgaac ttgaagaatc tcagaacaca agttactcat
    12181 gataatcttt ccatcgacag gatttgcacg gttagccgta tctatgttga ctacataagg
    12241 atagccagac tcttgttgca atttagagat ttcagtttcc aaatcccgcg ccttgatttt
    12301 tgtcttgcga atatttggat ttgcgaccaa ttcatcgtat ttttcagtaa tgtcgatgta
    12361 attgaatggc acaccgtatt ctttttctac agagtaaggg ctgaagaggt acatttcttc
    12421 atttttacga gccaattcgt agaatttatc aggtactaca acaccaagtg atagagtctt
    12481 gacacgtact ttttcatcag cgttttcttt cttagttgaa aggaaagcga tgatatctgg
    12541 gtgaaagacg ttgaggtaga caacaccggc accttgacgt tgccccaatt ggttggagta
    12601 agagaagctg tcttcaaaaa gcttcataac aggaacgaca cctgaagcag ctccttcata
    12661 gcctttgata ggtgcaccag cttcacgaag gttgctgagg gtaattccca caccaccacc
    12721 aatacgtgaa agttgaagag ctgagttgat agaacgtccg atagagttca tatcatccgt
    12781 cacttggatt aggaaacaag ataccaactc cccacgacga gcacgtccag cattcaagaa
    12841 ggaaggagta gcaggttggt agcgttggtg gatgatttca ttggcaatat cgattgcaac
    12901 agcttcattc ccatcagcga aataaagggc gttgaagaag acacggtctt ccatattttc
    12961 aagatagtat tcaccgtcat tagtctttaa ggcatattga ttgtaaaatt tataagctgc
    13021 catgaatgac ttgaattgga agttttggtc tttgataaat tgagccaatt cttccaagaa
    13081 ctctggacgg tatttcttga taaaggctgt ttcgatgtag ttgtgttcaa tgaggtaatt
    13141 gattttgtct ttgattgaat caaaaaccat agtgtttgga actacatttt ctttaaagaa
    13201 agcatccaag gcttccttat ctttatgaag catgatttgt ccattaacag gacggttaat
    13261 ttcgttatta agacggaagt aagtcacgtc ttcaagatgt tttaatccca taaaatttcc
    13321 cttatctaat tacaaaagaa aggcttctaa gttagcccta aaagcagttt cttctggatg
    13381 atgtactaag attatgctaa ttgtttcagt ttttctggtt ggaaacctga aaagacttca
    13441 gttggtgttt ggataacagg agctgcgcta aaaccgagct ctttaacttg atcgacgtac
    13501 tcaggttgct catcaagatt gatttcacga taagagacat tattactgtc caagaaacgc
    13561 ttggtcattt tacattggac acaattgttt ttagaataaa cggttaccat tgtgtaactc
    13621 ctcttcaaaa tttaatacta tcttagtata tcagaaaata aaattttgtc aatgatttaa
    13681 actaaatata gtggtgttct tttgttgttt ttatatataa acacaatata tagtgtttgt
    13741 attgtgaaat agcaatgatt atcctataaa ttgtttttga agaaactata tcctgtgttt
    13801 tgttatctag gatagaagat tttcagcaag ttatctgaaa ggaaattgaa ggaaaatcca
    13861 gaaaatgctt gaaaaaaatc ctagaagatg gtataatact aaattgtaag ggttatcaca
    13921 tataactcaa aaaaagaaag aacaaaagga gagtcaaact atggcttcta aagatttcca
    13981 cgtagtggca gaaacaggta ttcacgcacg tccagcaaca ttgttggtac aaactgctag
    14041 caaatttgct tcagatatca ctcttgagta caaaggtaaa tcagttaacc ttaaatcaat
    14101 tatgggtgtt atgagtcttg gtgttggtca aggtgctgac gtaactatct cagctgaagg
    14161 tgcagatgca gatgacgcta tcgctgcaat ctcagaaaca atggaaaaag aaggattggc
    14221 ataagggaaa tgacagaaat gcttaaagga atcgcagcat ctgacggtgt tgcagttgca
    14281 aaagcatatc tactcgttca gccggatttg tcatttgaga ctattacagt cgaagataca
    14341 aacgcagaag aagctcgcct tgatgccgct ctacaggcat cacaagacga gctttctgtt
    14401 attcgcgaga aagcagtagg tacgctcggt gaagaagcag ctcaagtttt tgatgctcac
    14461 ttaatggttc ttgctgaccc agaaatgatc agccaaatca aggaaactat ccgtgcgaag
    14521 aaagtgaatg cagaagcagg tctgaaagaa gttacagata tgtttatcac tatctttgaa
    14581 ggcatggaag acaacccata catgcaagaa cgcgcagcgg atatccgcga cgtgacaaaa
    14641 cgtgtattgg caaaccttct tggtaaaaaa ttgccaaacc cagcttctat caatgaagaa
    14701 gtgattgtga ttgcgcatga cttgactcct tcagatacag ctcaattgga caaaaacttt
    14761 gtaaaagctt ttgtaaccaa cattggtgga cgtacaagcc actcagctat catggcacgt
    14821 acacttgaaa ttgctgctgt attaggtaca aacaacatca ctgaaatcgt taaagacggt
    14881 gacatccttg ctgttaacgg gatcactgga gaagtgatta tcaacccgac agatgaacaa
    14941 gcggcagaat ttaaagcagc tggtgaagcc tatgcgaaac aaaaagctga atgggcactt
    15001 ttgaaagatg ctcaaacagt gactgctgac ggtaaacact tcgagttggc tgccaatatt
    15061 ggtactccaa aagacgttga aggtgttaac aacaacggtg cagaagctgt tggactttac
    15121 cgtacagagt tcttgtacat ggattctcaa gacttcccaa ctgaagatga gcagtatgaa
    15181 gcatacaagg ctgttcttga aggaatgaac ggtaaacctg ttgtcgttcg tacaatggat
    15241 atcggtggag ataaggaact tccttacttc gatatgcctc acgaaatgaa cccattcctt
    15301 ggattccgtg ctcttcgtat ctctatctct gagactggag atgctatgtt ccgcacacaa
    15361 atccgtgctc ttcttcgtgc gtctgttcac ggtcaattgc gtatcatgtt cccaatggtt
    15421 gcgctcttga aagaattccg tgcagcgaaa gcagtctttg atgaagaaaa agcaaacctt
    15481 cttgctgaag gtgttgcagt tgcggataac atccaagttg gtatcatgat cgagattcct
    15541 gcagcggcta tgcttgcaga ccaatttgct aaagaagttg acttcttctc aattggtaca
    15601 aacgacttga tccaatatac aatggcagca gaccgtatga acgaacaagt ttcatacctt
    15661 taccaaccat acaacccatc aatcctacgc ttgattaaca atgtgatcaa agcagctcac
    15721 gctgaaggta aatgggctgg tatgtgtggt gagatggctg gtgaccaaca agctgttcca
    15781 cttcttgtcg gaatgggctt ggatgagttc tctatgtcag caacatctgt acttcgtaca
    15841 cgcagcttga tgaagaaact cgacacagct aagatggaag agtacgcaaa ccgtgccctt
    15901 acagaatgct caacaatgga agaagttctt gaacttcaaa aagaatacgt taattttgat
    15961 taatcgaaaa gtccctgcaa ctcagttaca gggacttttt ttgatatttt aaaaagaatt
    16021 ttcaagaaaa tctttcttat aaaaagtcca accttgaaaa agtagtggtc agaacaaaaa
    16081 atacttaaat ggttcataaa attcttgaca agttggagat ttaggagtaa actattaacc
    16141 agttaagtaa tagagaggag tttctgcaat ttagaaatga attgcaacta gaaatatcaa
    16201 atagaaagag agtttcgatg aaaattaata agaaatacct tgttggttct gcggcagctt
    16261 tgattttaag tgtttgttct tacgagttgg gactgtatca agctagaacg gttaaggaaa
    16321 ataatcgtgt ttcctatata gatggaaaac aagcgacgca aaaaacggag aatttgactc
    16381 ctgatgaggt tagcaagcgt gaaggaatca atgctgagca aatcgtcatc aagataacag
    16441 accaaggcta tgtcacttca catggcgacc actatcatta ttacaatggt aaggttcctt
    16501 atgatgcgat tttcagtgaa gaattactca tgaaagatcc aaactataag ctaaaagatg
    16561 aggatattgt taatgaggtc aagggtggat atgttatcaa ggtagatgga aaatactatg
    16621 tttaccttaa ggatgctgcc cacgcggata acgtccgtac aaaagaggaa atcaatcgac
    16681 aaaaacaaga acatagtcaa catcgtgaag gtgggactcc aagaaacgat ggtgctgttg
    16741 ccttggcacg ttcgcaagga cgctatacta cagatgatgg ttatatcttt aatgcttctg
    16801 atatcataga ggatactggt gatgcttata tcgttcctca tggagatcat taccattaca
    16861 ttcctaagaa tgagttatca gctagcgagt tagctgctgc agaagccttc ctatctggtc
    16921 ggggaaatct gtcaaattca agaacctatc gccgacaaaa tagcgataac acttcaagaa
    16981 caaactggct accttctgta agcaatccag gaactacaaa tactaacaca agcaacaaca
    17041 gcaacactaa cagtcaagca agtcaaagta atgacattga tagtctcttg aaacagctct
    17101 acaaactgcc tttgagtcaa cgccatgtag aatctgatgg cctt
//
LOCUS       DBEJHE010000036        15760 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC4 isolate 671759
            SAMN38261586-rid24793303.denovo.36, whole genome shotgun sequence.
ACCESSION   DBEJHE010000036 DBEJHE010000000
VERSION     DBEJHE010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261586
            Sequence Read Archive: SRR26833752
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 15760)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15760)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576136.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576136.1
            Genome Coverage       :: 109x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 19:48:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,067
            CDSs (total)                      :: 2,029
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 131
            CDSs (without protein)            :: 131
            Pseudo Genes (ambiguous residues) :: 0 of 131
            Pseudo Genes (frameshifted)       :: 64 of 131
            Pseudo Genes (incomplete)         :: 59 of 131
            Pseudo Genes (internal stop)      :: 46 of 131
            Pseudo Genes (multiple problems)  :: 32 of 131
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15760
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261586-rid24793303.denovo.36"
                     /strain="GPSC4"
                     /isolate="671759"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(117..914)
                     /gene="proC"
                     /locus_tag="ACL3EZ_001708"
     CDS             complement(117..914)
                     /gene="proC"
                     /locus_tag="ACL3EZ_001708"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004735 - pyrroline-5-carboxylate
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HGR0393245.1"
                     /translation="MKIGFIGLGNMGASLAKSVLQTRTSDEILLANRSQAKVDAFIAD
                     FGGQASSNEEMFAEADVIFLGVKPAQFSELLSQYQTILEKRESLLLISMAAGLTLEKL
                     ASLIPSQHRIIRMMPNTPASIGQGVISYALSPNCRAEDSEIFCQLLAKAGLLVELGES
                     LINAATGLAGCGPAFVYLFIEALADAGVQTGLPRETALKMAAQTVVGAGQLVLESQQH
                     PGVLKDQVCSPGGSTIAGVASLEAHAFRGTVMEAVHQAYKRTQELGK"
     gene            complement(918..2180)
                     /locus_tag="ACL3EZ_001709"
     CDS             complement(918..2180)
                     /locus_tag="ACL3EZ_001709"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004350 - glutamate-5-semialdehyde
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HGR0393246.1"
                     /translation="MVSRQEQFEQVQAVKKSINTASEEVKNQALLAMADHLVAATEEI
                     LAANALDMAAAKGKISDVMLDRLYLDADRIEAMARGIREVVALPDPIGEVLETSQLEN
                     GLVITKKRVAMGVIGIIYESRPNVTSDAAALTLKSGNAVVLRSGKDAYQTTHAIVTAL
                     KKGLETTTIHPNVIQLVEDTSRESSYAMMKAKGYLDLLIPRGGAGLINAVVENAIVPV
                     IETGTGIVHVYVDKDADEDKALSIINNAKTSRPSVCNAMEVLLVHENKAASILPRLDQ
                     MLVADRKEAGLEPIQFRLDSKASQFVSGQAAQAQDFDTEFLDYILAVKVVSSLEEAVA
                     HIESHSTHHSDAIVTENAEAAAYFTDQVDSAAVYVNASTRFTDGGQFGLGCEMGISTQ
                     KLHARGPMGLKELTSYKYVVAGDGQIRE"
     gene            complement(2190..3299)
                     /gene="proB"
                     /locus_tag="ACL3EZ_001710"
     CDS             complement(2190..3299)
                     /gene="proB"
                     /locus_tag="ACL3EZ_001710"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000875748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004349 - glutamate 5-kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HGR0393247.1"
                     /translation="MKYKRIVFKVGTSSLTNEDGSLSRSKVKDITQQLAMLHEAGHEL
                     ILVSSGAIAAGFGALGFKKRPTKIADKQASAAVGQGLLLEEYTTNLLLRQIVSAQILL
                     TQDDFVDKRRYKNAHQALSVLLNRGAIPIINENDSVVIDELKVGDNDTLSAQVAAMVQ
                     ADLLVFLTDVDGLYTGNPNSDPRAKRLERIETINREIIDMAGGAGSSNGTGGMLTKIK
                     AATIATESGVPVYICSSLKSDSMIEAAEETEDGSYFVAQEKGLRTQKQWLAFYAQSQG
                     SIWVDKGAAEALSQHGKSLLLSGIVEAEGVFSYGDIVTVFDKESGKSLGKGRVQFGAS
                     ALEDMLRSQKAKGVLIYRDDWISITPEIQLLFTEF"
     gene            complement(3400..5283)
                     /gene="cbpE"
                     /locus_tag="ACL3EZ_001711"
                     /gene_synonym="pce"
     CDS             complement(3400..5283)
                     /gene="cbpE"
                     /locus_tag="ACL3EZ_001711"
                     /gene_synonym="pce"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine esterase CbpE"
                     /protein_id="HGR0393248.1"
                     /translation="MKKKLTSLALVGAFLGLSWYGNVQAQESSGNKIHFINVQEGGSD
                     AIILESNGHFAMVDTGEDYDFPDGSDSRYPWREGIETSYKHVLTDRVFRRLKELGVQK
                     LDFILVTHTHSDHIGNVDELLSTYPVDRVYLKKYSDSRITNSERLWDNLYGYDKVLQT
                     AAEKGVSVIQNITQGDAHFQFGDMDIQLYNYENETDSSGELKKIWDDNSNSLISVVKV
                     NGKKIYLGGDLDNVHGAEDKYGPLIGKVDLMKFNHHHDTNKSNTKDFIKNLSPSLIVQ
                     TSDSLPWKNGVDSEYVNWLKERGIERINAASKDYDATVFDIRQDGLVNISTSYKPIPS
                     FQAGWHKSSYGNWWYQAPDSTGEYAVGWNEIKGEWYYFNQTGILLQNQWKKWNNRWFY
                     LTDSGVAAKNWKKIAGIWYYFNKENQMEIGWIQDKEQWYYLDVDGSMKTGWLQYKGQW
                     YYFAPSGEMKTGWVKDKEAWYYMDSTGIMKTGEIEVAGHHYYLEESGAMKQGWLKKAN
                     DWYFYKTDGSRAIGWIKDKDKWYFLKENGQLLVNGKTPEGYTVDSSGAWLVDVPIEKS
                     ATIKTTSHSEIKESKEVVKKDLENKETSQHESVTNSSTSQDLTSSTSQSSETSVNKSE
                     SEQ"
     gene            complement(5286..6173)
                     /locus_tag="ACL3EZ_001712"
     CDS             complement(5286..6173)
                     /locus_tag="ACL3EZ_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HGR0393249.1"
                     /translation="MEIKIETGGLRLDKALSDLSELSRSLANEQIKSGQVLVNGQVKK
                     AKYTVQEGDVVTYHVPEPEVLEYVAEDLPLEIVYQDEDVAVVNKPQGMVVHPSAGHTS
                     GTLVNALMYHIKDLSGINGVLRPGIVHRIDKDTSGLLMIAKNDDAHLVLAQELKDKKS
                     LRKYWAIVHGNLPNDRGVIEAPIGRSEKDRKKQAVTAKGKPAVTRFHVLERFGDYSLV
                     ELQLETGRTHQIRVHMAYIGHSVAGDEVYGPRKTLKGHGQFLHAKTLGFTHPRTGKTL
                     EFKADIPEIFKETLERLRK"
     gene            complement(6163..6624)
                     /gene="lspA"
                     /locus_tag="ACL3EZ_001713"
     CDS             complement(6163..6624)
                     /gene="lspA"
                     /locus_tag="ACL3EZ_001713"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HGR0393250.1"
                     /translation="MKKRAIVAVIVLLLIGLDQLVKSYIVQQIPLGEVRSWIPNFVSL
                     TYLQNRGAAFSILQDQQLLFAVITLVVVIGAIWYLHKHMEDSFWMVLGLTLIIAGGLG
                     NFIDRVSQGFVVDMFHLDFINFAIFNVADSYLTVGVIILLIAMLKEEINGN"
     gene            complement(6621..7529)
                     /locus_tag="ACL3EZ_001714"
     CDS             complement(6621..7529)
                     /locus_tag="ACL3EZ_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HGR0393251.1"
                     /translation="MNIQQLRYVVAIANSGTFREAAEKMYVSQPSLSISVRDLEKELG
                     FKIFRRTSSGTFLTRRGMEFYEKAQELVKGFDIFQNQYANPEEEKDEFSVASQHYDFL
                     PPTITAFSERYPDYKNFRIFESTTVQILDEVAQGHSEIGIIYLNNQNKKGIMQRVEKL
                     GLEVIELIPFHTHIYLCEGHPLAQKEELVMEDLADLPTVRFTQEKDEYLYYSENFVDT
                     SASSQMFNVTDRATLNGILERTDAYATGSGFLDSDSVNGITVIRLKDNLDNRMVYVKR
                     EEVELSQAGTLFVEVMQEYFDQKRKS"
     gene            7522..7719
                     /locus_tag="ACL3EZ_001715"
     CDS             7522..7719
                     /locus_tag="ACL3EZ_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HGR0393252.1"
                     /translation="MFIFYPQLLYLFIIPYFRSFPKRKKEHPILLNYLHYLPFSRQSY
                     FQNQFKKISGYTPLQYRKEKR"
     gene            complement(7771..8442)
                     /locus_tag="ACL3EZ_001716"
     CDS             complement(7771..8442)
                     /locus_tag="ACL3EZ_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysostaphin resistance A-like protein"
                     /protein_id="HGR0393253.1"
                     /translation="MKKRAIQILLALSLIFYKSTWFWRVFNHLAKPYLPASREFFQIL
                     LLMESGVLFLAVIYLLVFAGKKIFHFKWQLRYFIYLLLGYIISYMSDFLFSYFISLSS
                     NQISLNETIEMMGRQEFPYFLLIVCFIAPIAEELIYRGVLMTTFFKNSPWYGDVLLSA
                     IIFGYIHINFALTPLAFFIYASGGLILALLYRMTKNLYYPILVHILINITAFWDVWLL
                     LFSGS"
     gene            complement(8496..8717)
                     /locus_tag="ACL3EZ_001717"
     CDS             complement(8496..8717)
                     /locus_tag="ACL3EZ_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000602450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0924 family bacteriocin-like peptide"
                     /protein_id="HGR0393254.1"
                     /translation="MILMTKNINLTNEELELIQGGADSYGKNPNGRYDWEIEPVLTLP
                     VHGFCSRGTYDLGYIGGGNHLCKGSAARF"
     gene            8989..9798
                     /locus_tag="ACL3EZ_001718"
     CDS             8989..9798
                     /locus_tag="ACL3EZ_001718"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HGR0393255.1"
                     /translation="MIKLLALDMDGTLLNEAKEIPQAHITAIHKAIEKGVKLVLCTGR
                     PLFGVLPYYKKLELDLQNEYIIVNNGCSTHQTSDWSLVDWKELSPADIEYLYDLAEKS
                     DVQLTLFDESHYFVLGGKPNQVIENDAKLVFSDLTEISLEEATSGKFRMFQGMFLGTK
                     EQTDDFEQRFAEELCQRFSGVRSQPVIYEAMPLGTTKATALSRLAEILKIDSSEIMAM
                     GDANNDIEMLQFAGLGIAMGNASDYVKSLADAVTSSNEEDGVARAIEKYIL"
     gene            complement(9979..10854)
                     /gene="aguB"
                     /locus_tag="ACL3EZ_001719"
     CDS             complement(9979..10854)
                     /gene="aguB"
                     /locus_tag="ACL3EZ_001719"
                     /EC_number="3.5.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0050126 - N-carbamoylputrescine amidase
                     activity [Evidence IEA];
                     GO_process: GO:0009446 - putrescine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-carbamoylputrescine amidase"
                     /protein_id="HGR0393256.1"
                     /translation="MRNVRVATIQMQCAKDVATNIQTAERLVRQAAEQGAQIILLPEL
                     FEHPYFCQERQYDYYQYAQSVAENTAIQHFKVIAKELQVVLPISFYEKDGNVLYNSIA
                     VIDADGGVLGVYRKTHIPDDHYYQEKFYFTPGNTGFKVWNTRYAKIGIGICWDQWFPE
                     TARCLALNGAELLFYPTAIGSEPILDTDSCGHWQRTMQGHAAANIVPVIAANRYGLEE
                     VTPSEENGGQSSSLDFYGSSFMTDETGAILERAERQEEAVLLATYDLDKGASERLNWG
                     LFRDRRPEMYRQITD"
     gene            complement(10864..11949)
                     /gene="aguA"
                     /locus_tag="ACL3EZ_001720"
     CDS             complement(10864..11949)
                     /gene="aguA"
                     /locus_tag="ACL3EZ_001720"
                     /EC_number="3.5.3.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0047632 - agmatine deiminase activity
                     [Evidence IEA];
                     GO_process: GO:0009446 - putrescine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="agmatine deiminase"
                     /protein_id="HGR0393257.1"
                     /translation="MMDSPKKLGYHMPAEYEPHHGTLMIWPTRPGSWPFQGKAAKRAF
                     TQIIETIAEGERVYLLVEQAYLSEAQSYLGDKVVYLDIPTNDAWARDTGPTILVNDKG
                     KKLAVDWAFNAWGGTYDGLYQDYEEDDQVASRFAEALERPVYDAKPFVLEGGAIHSDG
                     QGTILVTESCLLSPGRNPNLTKEEIENTLLESLGAEKVIWLPYGIYQDETNEHVDNVV
                     AFVGPAEVVLAWTDDENDPQYAMSKADLELLEQETDAKGCHFTIHKLPIPAVRQVVTE
                     EDLPGYIYEEGEEERYAGERLAASYVNFYIANKAVLVPQFEDVNDQVALDILSKCFPD
                     RKVVGIPARDILLGGGNIHCITQQIPE"
     gene            complement(11946..13073)
                     /gene="nspC"
                     /locus_tag="ACL3EZ_001721"
     CDS             complement(11946..13073)
                     /gene="nspC"
                     /locus_tag="ACL3EZ_001721"
                     /EC_number="4.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA];
                     GO_process: GO:0045312 - nor-spermidine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxynorspermidine decarboxylase"
                     /protein_id="HGR0393258.1"
                     /translation="MKLEQVPTPAYVIDLAKLEANCRILQYVQEEAGCKVLLAQKAYS
                     LYKTYPLISQYLSGTTASGLYEAKLAREEFPGEVHVFAPAFKDEDMEELLGITDHIVF
                     NSERQLRKHGARCREAGVSVGLRLNPQCSTQGDHALYDPCAPGSRFGVTIDKIPSDLL
                     DLVDGLHFHTLCEQGADDLQTTLKAVEEQFGPYLHEVKWLNMGGGHHITREGYDVDLL
                     ISEIKRIRKTYNLEIYIEPGEAIALNAGYLATEVLDIVENGMEILVLDASATCHMPDV
                     LEMPYRPPLRNGFESQEKAHTYRLSSNTCLTGDVIGDYSFENPVQIGDRLYFQDMAIY
                     SFVKNNTFNGIGLPSLYLMDEQGDCSLLKAFGYQDFKGRLS"
     gene            complement(13073..14332)
                     /locus_tag="ACL3EZ_001722"
     CDS             complement(13073..14332)
                     /locus_tag="ACL3EZ_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000088792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="saccharopine dehydrogenase family protein"
                     /protein_id="HGR0393259.1"
                     /translation="MSRLLVIGCGGVAQVAISKICQDSETFTEIMIASRTKSKCDDLK
                     AKLEGKTSTKIETAALDADKVEEVIALIESYKPEAVLNVALPYQDLTIMDACLATGVH
                     YIDTANYEAEDTEDPEWRAIYEKRCKELGFTAYFDYSWQWAYQEKFKEAGLTALLGSG
                     FDPGVTSVFSAYALKHYFDEIHYIDILDCNGGDHGYPFATNFNPEINLREVSAPGSYW
                     EDGKWVEVEAMSIKREYDFPQVGQKDMYLLHHEEIESLAKNIPGVKRIRFFMTFGQSY
                     LTHMKCLENVGLLRTDTINFNGQEIVPIQFLKALLPDPASLGPRTVGKTNIGCIFTGV
                     KDGVEKTIYIYNVCDHQECYAEVGSQAISYTTGVPAMIGTKLVMNGTWKQAGVYNLEE
                     LDPDPFMEALNEYGLPWVVVENPQMVD"
     gene            complement(14329..15189)
                     /gene="speE"
                     /locus_tag="ACL3EZ_001723"
     CDS             complement(14329..15189)
                     /gene="speE"
                     /locus_tag="ACL3EZ_001723"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HGR0393260.1"
                     /translation="MDLWFSEVHTPDVKLSLRTAKQLYAGKSEWQDIEVLDTPAFGKI
                     LILNGHVLFSDADDFVYNEMTVHVPMAVHPNPKKVLVIGGGDGGVAQVLTLYPELEQI
                     DIVEPDEMLVEVCREYFPDFAAGLDDPRVTIYYQNGLRFLRNCEDDYDIIINDATDPF
                     GHTEGLFTKEFYGNSYRALKEDGIMIYQHGSPFFDEDESACRSMHRKVNQAFPISRVY
                     QAHIPTSPAGYWLFGFASKKYHPVKDFDKEGWKKRQLFTEYYTANLHVGSFMLPKYVE
                     DILEEEEGKK"
     gene            15445..>15760
                     /locus_tag="ACL3EZ_001724"
     CDS             15445..>15760
                     /locus_tag="ACL3EZ_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGR0393261.1"
                     /translation="MLYVGIDVAKNKHDVTALNVPGKTVLKPLTFSNNKAGFELLDLS
                     LRQLNQDCLIALENTGHYAFNLLNFLHEQGYKVYTYNPLLIKEFAKSLSLHKTKTDKK
                     DAH"
BASE COUNT         4634 a         3639 c         2867 g         4620 t
ORIGIN      
        1 aaactaggaa gctagccgca ggctgtactt gagtacggca aggtgaagct gacgcagttt
       61 gaatttgatt ttcgaagagt atcaaccacc ataaaagagg cagataaaac tacctcttat
      121 ttacctagtt cttgtgttcg tttataggct tgatgaactg cctccatgac tgtgcctcga
      181 aaagcatgcg cttctaggct tgctacgcca gcaatagtcg aaccgcctgg actacaaact
      241 tgatctttca aaactccagg atgttgctgg ctttctagga ccaattgccc agctcctacc
      301 acagtttggg ctgccatttt caaggctgtt tctcgtggta atcccgtctg aacacctgca
      361 tctgccaagg cctcaataaa gagatagaca aaggctggtc cacaacctgc aagacctgtc
      421 gctgcattga ttaagctttc tcctaattca accaagagac cagccttggc taaaagctga
      481 caaaagatct cactgtcctc agccctgcaa ttaggagaca aggcataact aatcactcct
      541 tgcccgatag aagcaggggt attaggcatc atacgaataa ttcggtgttg gcttgggata
      601 agacttgcta gtttttctaa ggtcaatcca gctgccatcg aaatcaaaag aagactttct
      661 cttttttcaa ggatggtctg atattgagaa agcagttcag aaaactgagc aggcttaact
      721 cctagaaaaa tcacatctgc ttctgcaaac atttcttcat tgctggaagc ctgaccacca
      781 aagtctgcaa tgaaagcatc taccttagct tgactacgat tggcaaggag aatctcatct
      841 gacgtcctag tctgcaagac agattttgcc aagctagcac ccatattccc caaaccgata
      901 aatccaatct tcatctctta ctcccttatc tgcccatcac cagcaaccac atacttgtag
      961 ctggtcaact ctttcaagcc cattggacca cgcgcgtgca atttctgagt agaaatcccc
     1021 atttcacaac caagaccaaa ttgtcctcca tctgtgaaac gagttgaggc attaacatac
     1081 accgctgcag agtccacttg atctgtaaag tatgctgcag cttcagcatt ttccgtcaca
     1141 atagcatccg aatgatgggt actgtgggat tcaatatgcg caaccgcttc ttctaaactg
     1201 ctcacaacct taacagctag aatatagtct aaaaactcgg tatcaaagtc ttgtgcttga
     1261 gcagcttgac ctgaaacaaa ctggcttgct ttgctatcta ggcggaattg aattggttcc
     1321 aacccagctt cttttcgatc tgcaaccaac atttgatcca agcgaggaag gatgcttgct
     1381 gccttgtttt catgaaccag cagaacctcc atggcattac aaacagaagg acgactggtt
     1441 ttagcattgt tgatgataga cagcgccttg tcttcgtctg catccttatc cacatagaca
     1501 tggacaatcc cagtccctgt ctcgataaca ggtacaatcg cattctcaac cactgcattg
     1561 atcaagccag ctcctccacg aggaatgaga aggtctagat agcccttggc cttcatcata
     1621 gcataactac tttcacggct agtatcctcc accagttgaa tcacatttgg atgaatagta
     1681 gtcgtctcca agcccttctt caaggctgtg acaatggcat gggttgtttg ataggcatcc
     1741 ttaccactac gaagaacaac cgcatttcca ctcttaagag tcaaagcagc cgcatcagac
     1801 gtcacatttg gacggctttc atagataata ccgatgacac ccatagctac acgttttttt
     1861 gtgataacca aaccattttc aagctgactt gtttctaaaa cttcaccgat tggatctggt
     1921 aaggcaacca cttcacgaat tcctcttgcc atcgcttcta tacgatctgc atccaaataa
     1981 agacgatcca acatcacatc tgagattttc cccttagccg ctgccatatc gagggcatta
     2041 gccgctaaaa tttcctcagt agcagccact aagtgatcag ccatggctag caaggcttgg
     2101 tttttcactt cttcactagc tgtgttaatc gattttttaa cagcctgtac ctgttcaaat
     2161 tgttcttgtc tactcaccat agtttacctc taaaattctg taaaaagtag ttggatttca
     2221 ggagtaatgg aaatccagtc gtcacggtaa atcaagacac ccttggcttt ttgagaacgc
     2281 aacatatcct ccaaagcaga tgctccaaat tgcacgcgtc cttttccaag tgattttcca
     2341 ctttccttat caaatactgt cacgatatca ccgtaagaaa agactccttc tgcttcaacg
     2401 ataccagata agagaagact ctttccatgt tgagagagag cttccgcagc ccctttatca
     2461 acccaaatag aaccttgact ctgagcatag aaggcaagcc attgtttctg ggtacgaagc
     2521 cccttctctt gagcaacaaa gtaagaacca tcctcggtct cctctgccgc ctcaatcatg
     2581 gaatctgatt tcaaggatga gcagatataa acaggaactc ctgattccgt cgcgatagtt
     2641 gcagccttga ttttggttaa cataccccca gttccgtttg acgaaccagc tccaccagcc
     2701 atatcaataa tctcacgatt gatggtctcg attctctcca agcgtttggc tcttggatct
     2761 gaattaggat ttccagtata gagaccgtcc acatctgtca agaaaactaa aaggtctgct
     2821 tggaccatcg ccgctacttg agcacttaga gtgtcattgt ccccaacctt gagctcatca
     2881 ataacgacac tatcattctc attgatgata ggaattgccc cacggttgag caaaaccgac
     2941 aaagcctgat gggcattttt ataacgacgc ttatccacaa agtcatcttg ggtcagcaag
     3001 atttgtgcag aaacgatttg acgcaagaga agattggtcg tatattcttc caacaaaagt
     3061 ccctgcccta ccgctgctga agcctgttta tcagcaattt tagtcggacg ctttttaaat
     3121 cctaaggctc caaaaccagc cgcaatggca cctgaagaca ccaaaatcaa ctcatgacca
     3181 gcctcgtgca gcatagccaa ctgctgggta atatccttta ccttactacg tgataaactt
     3241 ccatcctcat ttgtcagaga agaagtaccc accttaaaga caatccgttt gtatttcata
     3301 gtctcactcc gattattcat atttatccat tataacatga ataacaggaa atagaaaaga
     3361 gttgatagga aaaagaaggc cctaaaacct tcttttctac tactgttctg attccgattt
     3421 gtttacactc gtttcagagc tttgtgaagt tgaggatgtc aaatcttgac tagttgaaga
     3481 atttgtaaca ctttcatgtt gactcgtttc tttattttca agatcctttt tcactacttc
     3541 tttggattct tttatttctg aatgacttgt agttttaatt gtagcagatt tctcgatcgg
     3601 aacatccact aaccaggcac cacttgaatc cacagtatag ccttctggtg tcttaccatt
     3661 cacaagtaat tgaccatttt ctttcaagaa gtaccattta tccttgtctt taatccaacc
     3721 tatagctcgt gaaccatctg tcttgtagaa ataccaatca tttgcctttt taagccagcc
     3781 ttgcttcata gctcctgatt cttctagata gtaatgatgt ccagcaactt ctatctcacc
     3841 tgtcttcatg ataccagtag aatccatata gtaccaggct tctttatctt ttacccagcc
     3901 cgttttcatt tcccctgatg gagcaaagta ataccattgc cccttatatt gaagccaacc
     3961 tgtcttcata gagccatcaa catccaaata ataccactgc tctttatctt gaatccaacc
     4021 aatttccatc tggttttctt tgttaaaata ataccagatt ccagcgattt tcttccaatt
     4081 tttagcagca acaccagagt ctgtcaaata gaaccaacga ttgttccatt ttttccattg
     4141 attctgtaat aagatacccg tttggttaaa gtaataccat tcacccttaa tttcattcca
     4201 accgacagca tattctcctg tagaatcagg cgcttgatac caccagtttc catatgaact
     4261 cttatgccaa ccagcttgaa aacttggaat cggcttgtag gaagttgaaa tgtttactaa
     4321 accgtcttgt cgaatatcaa aaactgttgc atcatagtct ttgctggctg cattgattct
     4381 ctcaattcct cgttctttga gccaattaac atactcacta tcaacaccat ttttccaagg
     4441 tagactatcc gaagtttgaa caatcaaact cggactcaaa tttttaatga aatccttggt
     4501 atttgatttg ttggtatcat ggtgatgatt aaacttcatc aaatcaactt ttccaatgag
     4561 aggaccatac ttgtcttctg ctccatgaac attatctaaa tcgcccccaa ggtaaatttt
     4621 cttgccattg actttcacca cgctaatcaa ggaattggaa ttgtcatccc aaattttctt
     4681 taattcaccc gatgaatcag tttcattttc ataattatag agctgaatat ccatgtcccc
     4741 aaactgaaaa tgagcatccc cttgtgtgat attttgaata actgaaacac ctttttctgc
     4801 agcagtctgt aaaaccttat catagccata cagattatcc catagacgtt cagaattagt
     4861 aatacgacta tcactatatt tcttaagata gactcggtca actggatagg tagacagtaa
     4921 ttcatcaaca tttccaatat gatcactgtg ggtatgggtc accaaaataa aatcaagttt
     4981 ttggacaccc aattccttca aacgacgaaa gacacggtct gttagaacat gcttataaga
     5041 cgtttcaatt ccttctctcc atggatagcg agaatcactt ccatctggga aatcataatc
     5101 ttctcctgta tccaccatgg caaaatgtcc attgctttca agaataatcg catcactgcc
     5161 accttcttga acattgataa agtggatttt atttcctgaa ctttcttgag cctgaacatt
     5221 cccataccat gacaaaccta aaaaagcgcc tacaagtgct aaactagtta atttcttttt
     5281 cattcttact ttctcaatct ctccaaggtt tccttaaaaa tctctgggat atctgcttta
     5341 aattccaagg tcttacctgt tctcggatga gtaaaaccta aagtcttggc atgaagaaat
     5401 tgtccatgtc ctttcaaagt cttgcgagga ccatagacct catcaccagc gactgaatgg
     5461 ccgatataag ccatgtggac acggatttga tgagtgcgcc ctgtctccag ttgcaactct
     5521 actaagctat aatcgccaaa gcgttccaag acgtgaaaac gcgtcactgc aggcttccct
     5581 ttagcagtta cagcctgttt cttacggtct ttttcactcc ggccaatcgg cgcttcaatt
     5641 acaccacgat cattaggcag atttccatga acaatcgccc aatatttgcg gagagacttt
     5701 ttatctttga gttcttgggc aagtactaga tgcgcatcat cgtttttagc aatcatgaga
     5761 agacctgacg tatccttatc aatacggtga acaatccctg gacgcagaac cccattgata
     5821 cccgacaagt ccttaatatg atacatgagg gcatttacta gggttccact ggtatgacca
     5881 gcactcgggt gcacaaccat tccctgaggt ttgttaacga cagccacatc ctcatcttgg
     5941 tagactattt ctagcggaag atcctcagcc acatactcta atacctctgg ttctggcaca
     6001 tggtaagtga cgacatcacc ctcttggact gtgtatttag ctttcttgac ttgaccattg
     6061 accaagacct ggcctgattt aatttgttca ttcgcgagac tacgtgataa ttctgacaaa
     6121 tctgacaaag ccttatccaa acgcagacca ccagtttcaa ttttaatttc catttatttc
     6181 ctcttttagc attgcaatca ataaaataat cactccaacc gtcagatagc tatctgccac
     6241 attgaaaatt gcaaagttga taaagtcaag gtggaacata tccacaacaa agccctgact
     6301 gaccctgtca ataaagtttc caagaccacc cgcgattatt agagtcaaac ccaagaccat
     6361 ccagaatgag tcctccatgt gtttatgtaa ataccaaatg gcacctatca cgacaaccag
     6421 agtaatgaca gcgaataaca actgctgatc ttgtaagata gaaaaggctg cacctcgatt
     6481 ttgcaggtag gtcaagctaa cgaaattggg gatccaggag cgcacttcac ccagtggaat
     6541 ctgctggacg atataagatt tgaccaactg atccagccca attaaaagca gtacaatgac
     6601 tgccactatt gctctttttt tcatgatttc ctcttttgat caaaatattc ttgcatgact
     6661 tctacgaaga gagtcccagc ttgactaagc tccacttctt cacgtttaac atagaccatg
     6721 cggttatcta ggttatcctt gagacgaata actgtaatgc cattaacact gtcactatct
     6781 aaaaatccag aacctgtcgc ataggcgtcc gtccgctcca aaataccatt caaggtggca
     6841 cggtctgtca cattaaacat ctgtgagcta gcgctggtat cgacaaagtt ctctgaataa
     6901 taaaggtact cgtctttctc ttgagtgaaa cgaaccgttg gtaaatccgc taaatcctcc
     6961 atgactaatt cctctttctg ggctaaagga tgaccctcac agagataaat atgggtatgg
     7021 aaaggaatca attcgatgac ctccagacct aacttttcaa cccgttgcat aatccccttt
     7081 ttattttgat tgttgaggta gataatccca atctcactat gcccttgcgc cacttcatct
     7141 aatatttgaa cagtagttga ttcaaaaata cggaagttct tatagtcagg atagcgctct
     7201 gaaaaggccg taatagttgg tggtaagaag tcatagtgct ggctagcaac ggaaaattca
     7261 tctttttctt cttcaggatt ggcatactga ttttgaaaaa tatcaaatcc tttaaccaat
     7321 tcttgcgctt tttcataaaa ttccatccca cgacgggtca agaaagtccc tgagctggtc
     7381 cgacggaaaa tcttaaagcc caactctttt tccaaatcac gaacagaaat agacagactc
     7441 ggctgactaa catacatctt ttcagcagct tcacgaaaag taccactatt ggcaatagcc
     7501 acaacatagc gtaattgttg aatgttcatc ttctaccccc aacttcttta tcttttcatt
     7561 ataccatatt ttagaagttt tccaaaaagg aaaaaagaac atcctattct tcttaactat
     7621 cttcactatc tgcctttctc acgccaatct tattttcaaa atcaattcaa aaaaataagt
     7681 ggctacacac cacttcagta tcggaaagaa aaacgttgac tatttgtgaa aaaagaaaat
     7741 gccggaaaat tccgacattt ttttagtaag ctaacttcct gaaaatagga gtaaccaaac
     7801 atcccagaag gcagtgatat tgatgagaat atgaactagt attggatagt agagattttt
     7861 agtcatgcga tacaatagag ctaaaatcag acctccacta gcataaatga aaaaagcaag
     7921 aggagttaaa gcaaaattga tatgaatata accgaaaata atagcagaaa gcaaaacatc
     7981 tccgtaccaa ggtgagtttt tgaaaaaggt tgtcataagc acacctcgat aaatcaattc
     8041 ctcagcaata ggggcgatga agcaaacgat gagcaagaaa taagggaact cctgtctccc
     8101 catcatttct atcgtttcat tcaaagaaat ctgatttgaa gacagggata tgaaatacga
     8161 aaagaggaag tcagacatat atgaaatgat gtagcccagt aaaaggtaga tgaagtacct
     8221 cagctgccac ttgaaatgaa aaattttctt tcctgcaaaa accagtagat agatgaccgc
     8281 taagaaaaga actccgctct ccatcaaaag cagaatctga aaaaattcac gacttgctgg
     8341 tagatagggc tttgcgaggt gattgaaaac tctccaaaac caagttgatt tgtaaaaaat
     8401 taaggacaat gctagtaaaa tttgaatagc ccgttttttc atattaaatt ctctgctttc
     8461 tccacttgtt tcttcatatt actaataaat tttacttaaa atctcgcagc acttcctttg
     8521 caaagatgat tgcctcctcc aatatatcct aaatcatagg tgcctctgga acaaaatcca
     8581 tgaaccggca gagttaatac tggttctatt tcccaatcgt acctaccatt aggattttta
     8641 ccatatgaat ctgctccacc ttgtatcagc tctaattctt catttgttag atttatattt
     8701 tttgtcatta aaatcatgat atatttcctc cattattctt cagattagtt gagtaatctg
     8761 atactcatac ctacttacaa aaaaactatt atattaagtt ggttttttaa tttgtctagt
     8821 tgcaacattg acaaacatag tatagcatat ctttgccaaa tatcctcttc aaatcatgaa
     8881 ttgtcatcaa aacatcttaa actataaaat caattagtct caagctttct atcaatttct
     8941 tctccaaaat atgctataat aatagcaaaa gataaagaag gaagacctat gattaaacta
     9001 ctagccttgg atatggacgg caccctcctc aatgaagcca aggaaatccc acaagctcac
     9061 attactgcta ttcacaaagc cattgaaaaa ggtgtcaaac tggttctctg tacgggtcgc
     9121 ccccttttcg gtgtcctccc ctactacaaa aaactggagc ttgacctcca gaacgaatat
     9181 attattgtta acaacggttg ttcaactcac cagaccagtg attggagtct agttgactgg
     9241 aaagaactga gtccagctga catcgaatac ctctatgacc ttgctgaaaa gagtgatgtt
     9301 cagttgacac tttttgacga gtcacattat tttgttctcg gtggcaaacc caatcaagtt
     9361 attgaaaatg atgctaaact agtattttca gacctgactg aaatttctct tgaagaagcg
     9421 actagtggaa agttccggat gttccaaggt atgtttttag gaacaaaaga acaaacagac
     9481 gattttgagc agcgttttgc tgaagagctt tgccaacgat tcagtggagt tcgttcgcag
     9541 cctgtcattt atgaagcaat gccgcttgga acgacaaagg ctactgctct ttcacgacta
     9601 gctgagattt tgaagattga ttcctcagag attatggcca tgggcgatgc taataacgat
     9661 atcgaaatgc tccagtttgc agggcttggg attgcaatgg gaaatgccag cgattatgtc
     9721 aaatctcttg cggatgccgt tacctcaagc aacgaagaag acggcgttgc gcgtgctatt
     9781 gagaaatata ttctataaaa aagaaaagca aatagacaga agttactgct atttgctttt
     9841 ttgctaatat tttaaaatac ggactaatca atagacaaga atagcgaatc ataaaaatcg
     9901 atttactaga tgccatagta tcttatagtt gctaataaga agttagtcta gcagaatgaa
     9961 tctctcattt ctcccacact aatctgtaat ttgtctatac atttctggtc ttctatctcg
    10021 aaacaagccc cagtttagac gttcacttgc tcccttgtct aggtcataag tagctaacag
    10081 aacagcttct tcttgtcttt cagctcgttc tagaatagct cctgtttcat ccgtcataaa
    10141 ggaggaaccg tagaagtcaa gactggaact ctgtccgcca ttttcctcac taggagtaac
    10201 ctcctctaaa ccataacgat tggctgcgat gactggaaca atattcgctg ctgcgtgccc
    10261 ttgcatagta cgttgccagt gaccacaact atctgtatcc aaaattggct ctgaaccgat
    10321 agctgtagga taaaagagca attcagcacc attcaatgca agacagcggg ctgtttcagg
    10381 gaaccattga tcccaacaga taccgatacc aatcttagca tagcgagtat tccagacctt
    10441 gaaaccagtg ttaccaggcg tgaaatagaa tttttcttga taataatggt catctggtat
    10501 atgggtcttt cgataaacgc ccagcactcc cccatctgca tcaatgacgg caatagagtt
    10561 atacaagaca ttaccatctt tttcatagaa actgattggt aaaacaactt gtagttcctt
    10621 agcaatcacc ttaaaatgct gaatggcagt attttccgct acagattggg catactggta
    10681 gtagtcatac tgacgttcct gacagaaata gggatgttca aacaactcgg gcaagagaat
    10741 aatttgggct ccttgctcag cagcctgacg tactaaacgc tctgcggttt ggatatttgt
    10801 tgccacatcc ttagcgcatt gcatctgaat ggttgcaact cttacatttc tcatcttttt
    10861 ctcctattct ggaatttgtt gggtgataca gtggatattg ccaccaccta agagaatatc
    10921 tctggctggt attccgacaa ctttacggtc tgggaaacac ttgctgagga tatctaaggc
    10981 cacttggtcg tttacatcct caaactgtgg aaccaagaca gccttgttgg cgatataaaa
    11041 gtttacgtag gaagctgcta gtcgttcacc tgcgtatcgc tcttcttctc cttcttcata
    11101 gatgtagcct ggcaaatctt cttctgtcac aacttgtcga actgcaggga taggcaattt
    11161 atgaatggtg aagtgacaac cttttgcatc tgtttcctgt tctaagagtt cgagatctgc
    11221 ttttgacatg gcatactggg gatcattttc gtcatctgtc caagccaaaa caacctcagc
    11281 aggaccaaca aaggcaacaa cattatcgac gtgttcattg gtttcatcct gataaatacc
    11341 ataaggaagc caaataactt tttcagcacc aagactttct aataatgtgt tttcaatctc
    11401 ctctttagtc aggttaggat tgcgaccagg actaagcaag caactttcag ttacgagaat
    11461 agttccttga ccatcgctat ggattgcgcc tccttccagt acaaaaggtt tagcatcata
    11521 gacaggcctt tccaaggcct cagcaaaacg actggctact tggtcatcct cttcataatc
    11581 ttgataaaga ccatcatagg tgcctcccca agcattaaag gcccaatcca cggctaattt
    11641 cttaccttta tcattgacga gaatggttgg gccagtatca cgcgcccagg catcattggt
    11701 gggaatgtct aaataaacaa ccttgtctcc aagataggat tgggcttcag atagataggc
    11761 ctgctccacc aaaagataga ctctttcccc ttctgctatg gtctcgatga tctgagtaaa
    11821 tgctctttta gcagcctttc cttgaaaagg ccatgatcct ggtcgagtcg gccatatcat
    11881 gagggtacca tgatggggtt cgtactctgc tggcatgtga tagcctaatt tttttggact
    11941 gtccatcatg ataatctccc tttaaagtct tgatagccaa aagctttgag taagctacag
    12001 tctccctgtt cgtccatgag atagagactt ggcaatccaa taccattaaa ggtattattt
    12061 ttgacaaaag aataaatggc catgtcttga aaataaagtc tgtctccgat ttggactgga
    12121 ttttcaaaac tataatcacc aatcacatcg ccagtcagac aggtattaga agaaagtctg
    12181 taggtatggg ctttttcctg tgactcaaag ccatttctca aaggtggacg atagggcatc
    12241 tcaagtacat caggcatatg gcaggtcgca gaggcgtcta aaaccaagat ttccataccg
    12301 ttttctacaa tatctaatac ctcagttgct aaataacccg cattaagcgc aatggcttca
    12361 ccaggctcga tatagatttc aagattgtaa gtttttcgga tacgcttgat ttctgaaatc
    12421 agcaaatcca catcgtaacc ttctcttgta atatgatgac caccacccat attgagccat
    12481 tttacctcat gtaagtaggg accaaactgt tcttctactg ctttcaaagt tgtttgtaaa
    12541 tcatctgctc cctgctcgca aagggtatga aaatgaagtc cgtcaaccaa atctagcaaa
    12601 tcactcggaa tcttgtctat agtaactcca aagcgagaac caggtgcaca agggtcatag
    12661 agcgcgtgat ctccttgagt tgaacactga gggttgaggc gcaaaccaac actgacacca
    12721 gcctctcgac aacgagcccc atgcttacgc aactgtctct ctgagttaaa gacgatatgg
    12781 tctgttatcc caagcaattc ctccatgtcc tcatccttga aagctggtgc aaaaacatgg
    12841 acttcaccag gaaattcttc ccttgccaat ttggcctcat agagtccact agctgtcgta
    12901 cctgatagat actggctaat caagggataa gttttgtaga gggaatatgc cttctgggca
    12961 agcaagacct tgcaaccggc ctcttcttgt acatattgta gaatgcggca attagcttct
    13021 aacttggcca agtcaataac ataggctggt gttggtactt gttctaactt cattagtcca
    13081 ccatttgtgg attttcaacc acaacccatg gcaaaccata ctcattcaaa gcttccatga
    13141 atggatctgg atctaactcc tcaaggttat acactccagc ttgtttccaa gttccgttca
    13201 tgactaattt tgtcccaatc atggctggaa cgcctgtcgt gtatgaaatt gcttgtgacc
    13261 cgacttctgc atagcactct tgatggtcgc aaacattgta gatgtagata gtcttttcaa
    13321 cgccatcttt gacacctgta aagatacatc caatattggt tttacctaca gtacgtgggc
    13381 caaggctagc aggatctgga agcaaggctt tcaaaaattg aattggaaca atttcttggc
    13441 cgttaaagtt aatggtatcc gtacgaagga gtccaacatt ttcaagacat ttcatgtgcg
    13501 tcaagtaaga ttgaccaaaa gtcataaaga aacgaatgcg tttgacacct ggaatgttct
    13561 tggccaatga ttcgatttct tcatggtgaa ggagatacat atctttttgt ccaacttgag
    13621 ggaaatcata ctcacgcttg atagacatag cttcgacttc gacccatttc ccatcttccc
    13681 agtaagaacc tggcgcagaa acctcacgga gattaatttc tggattaaag ttggttgcaa
    13741 atggataacc gtggtcaccg ccattacagt ctaaaatgtc gatataatgg atttcatcaa
    13801 aatagtgttt gagggcataa gctgaaaaga cactagttac acctgggtca aaaccagaac
    13861 caagaagagc agtcaagcct gcttctttga atttctcttg ataagcccac tgccatgagt
    13921 agtcaaagta ggctgtaaaa ccaagttcct tacaacgttt ttcgtagata gcacgccact
    13981 cagggtcttc tgtgtcttct gcttcgtagt tggctgtatc gatatagtga acacctgttg
    14041 ccaaacaagc atccataatg gttaaatctt gataaggcag agctacattc aaaacagctt
    14101 ctggtttgta gctttcaatc agggcaatca cttcttcaac cttgtcagca tcaagtgctg
    14161 cagtttcaat tttagtactt gttttgcctt ctagcttcgc tttcaagtca tcgcattttg
    14221 acttggtacg gctagcaatc ataatctctg taaatgtttc gctatcttga caaatctttg
    14281 aaatagcaac ttgggcaacg cccccacaac caataactag taaacgactc atttttttcc
    14341 ttcctcttct tctaaaatgt cctcaacata cttgggcaac ataaaggatc ccacgtgtaa
    14401 gtttgcagtg tagtattctg tgaaaagctg gcgttttttc caaccttcct tgtcaaaatc
    14461 tttgacaggg tggtattttt tcgatgcaaa tccaaacaac caatagccag ctgggctagt
    14521 tggaatatgg gcctgataaa cccgactgat tggaaaggct tgattgacct tgcggtgcat
    14581 gcttcggcag gccgactcat cctcgtcaaa gaagggactc ccatgctggt aaatcatgat
    14641 gccgtcttcc ttcagagctc gataactatt gccgtagaat tccttggtaa agagtccttc
    14701 cgtatggcca aatggatctg tcgcatcgtt gatgataata tcgtaatcat cttcgcagtt
    14761 tcgcaaaaag cgtagcccat tttggtagta aatggtaaca cgaggatcat ctagccctgc
    14821 agcaaagtct gggaaatact cacgacagac ctcgaccaac atctcatccg gttccacgat
    14881 atcgatttgt tccagttcag gatagagtgt taatacttgg gcaacaccgc cgtcaccacc
    14941 cccaataacc aatactttct ttggatttgg gtggacagcc atgggaacgt gaacggtcat
    15001 ttcattgtag acgaaatcat ccgcatctga gaacaagaca tggccattta aaatcagtat
    15061 tttcccaaaa gctggcgtat ccaagacttc gatatcctgc cattcacttt ttccagcgta
    15121 aagttgcttg gctgttctca gagacaattt gacatctgga gtatgaactt cagaaaacca
    15181 taaatccatc tatttctcct tatattatat ttagcgcagt tagctactgc caaagcccaa
    15241 gtggtatact tggaataagc cactgtggat tagtttattc cctccaatcg cttgacgatt
    15301 tccgaaaggc tctaaccaca gttttttgtt tcaattggta atgagtttga taacgcatag
    15361 acgttttatc tcgtctaagg taacaaggca aaaaattcgt ggataaccaa gtagacttga
    15421 aatactacat ctggaggtac tcccatgctt tatgtgggca ttgatgtcgc taaaaataaa
    15481 cacgatgtta cagccttgaa tgttccagga aaaactgttc ttaaaccact cactttttca
    15541 aataataaag ctggttttga actcttagat ctgtctcttc gacaactcaa ccaagactgt
    15601 ctcatcgctc ttgaaaatac cggacattat gcctttaatc tactgaactt cctgcatgaa
    15661 caaggatata aagtttacac ctacaatcct ttgctcatca aggaatttgc caaatcatta
    15721 tcacttcaca agactaaaac ggataagaaa gacgctcatg
//
LOCUS       DBEJHE010000037        15491 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC4 isolate 671759
            SAMN38261586-rid24793303.denovo.37, whole genome shotgun sequence.
ACCESSION   DBEJHE010000037 DBEJHE010000000
VERSION     DBEJHE010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261586
            Sequence Read Archive: SRR26833752
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 15491)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15491)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576136.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576136.1
            Genome Coverage       :: 109x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 19:48:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,067
            CDSs (total)                      :: 2,029
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 131
            CDSs (without protein)            :: 131
            Pseudo Genes (ambiguous residues) :: 0 of 131
            Pseudo Genes (frameshifted)       :: 64 of 131
            Pseudo Genes (incomplete)         :: 59 of 131
            Pseudo Genes (internal stop)      :: 46 of 131
            Pseudo Genes (multiple problems)  :: 32 of 131
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15491
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261586-rid24793303.denovo.37"
                     /strain="GPSC4"
                     /isolate="671759"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            1..498
                     /locus_tag="ACL3EZ_001725"
                     /pseudo
     CDS             1..498
                     /locus_tag="ACL3EZ_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001839528.1"
                     /note="internal stop; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(533..1330)
                     /locus_tag="ACL3EZ_001726"
                     /pseudo
     CDS             complement(533..1330)
                     /locus_tag="ACL3EZ_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436304.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            1596..1832
                     /gene="comW"
                     /locus_tag="ACL3EZ_001727"
     CDS             1596..1832
                     /gene="comW"
                     /locus_tag="ACL3EZ_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma(X)-activator ComW"
                     /protein_id="HGR0393262.1"
                     /translation="MLQKIYEQMANFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVR
                     YGIGCHRDFIVYHYRVAYRLYLEKLVMNRGFISC"
     gene            2063..3349
                     /locus_tag="ACL3EZ_001728"
     CDS             2063..3349
                     /locus_tag="ACL3EZ_001728"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000205044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004019 - adenylosuccinate synthase
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HGR0393263.1"
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSANAEVIARYQGGDNAGHTIV
                     IDGKKFKLHLIPSGIFFPEKISVIGNGMVVNPKSLVKELSYLHEEGVTTDNLRISDRA
                     HVILPYHIELDRLQEEAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDKDIFRERL
                     ERNLAEKNRLFEKLYDSKAIVFDDIFEEYYEYGQQIKKYVIDTSVILNDALDNGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKIDKVVGVCKAYTSRVGDGP
                     FPTELFDEVGERIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVL
                     SGLDTVKICVAYDLDGQRIDYYPASLEQLKRCKPIYEELPGWSEDITGVRNLEDLPEN
                     ARNYVRRVSELVGVRISTFSVGPGREQTNILESVWS"
     gene            3550..4017
                     /gene="tadA"
                     /locus_tag="ACL3EZ_001729"
     CDS             3550..4017
                     /gene="tadA"
                     /locus_tag="ACL3EZ_001729"
                     /EC_number="3.5.4.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008251 - tRNA-specific adenosine
                     deaminase activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0002100 - tRNA wobble adenosine to inosine
                     editing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA adenosine(34) deaminase TadA"
                     /protein_id="HGR0393264.1"
                     /translation="MYYTLEEKEVFMREALREAEIALEHDEIPIGCVIVKDGEIIGRG
                     HNAREELQRAVMHAEIMAIEDANLSEESWRLLDCTLFVTIEPCVMCSGAIGLARIPNV
                     VYGAKNQKFGAAGSLYDILTDERLNHRVEVEIGILEDECAAIMQDFFRNRRKK"
     gene            4050..4143
                     /gene="ffs"
                     /locus_tag="ACL3EZ_001730"
     ncRNA           4050..4143
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="ACL3EZ_001730"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(4226..4942)
                     /locus_tag="ACL3EZ_001731"
     CDS             complement(4226..4942)
                     /locus_tag="ACL3EZ_001731"
                     /inference="COORDINATES: protein motif:HMM:NF012798.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGR0393265.1"
                     /translation="MKFAIRMNYIDTNEMLFVETPRKVITSDELRKKNTKYLDQKEFK
                     LFIQNLKDEALCDYRITKYIRIAKVLFLTGMRYGELAALNYKEDIDFSKKTIHIKHTY
                     DFRQKERTTPKTIKSDRVITAPQKVLDIIKEQIIENATNGFDTDFIFINTLGEPITNA
                     RVICALKRHGQKIGIEKNITTHTFRHSHISLLAELGIPLTAIMDRVGHSDSKTTLEIY
                     SHVTQKMVSDISSKLDKIKF"
     gene            complement(5014..5361)
                     /locus_tag="ACL3EZ_001732"
     CDS             complement(5014..5361)
                     /locus_tag="ACL3EZ_001732"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0393266.1"
                     /translation="MEELPNGKYKFFERYKDPYTEKLKKVSVTMEKKTPQARNQAAIL
                     LQEKIKQKLGEKQHSVSNITFEKLYEEFEENWKHGVKNSTVYASKNVKKEILKQIEGD
                     YLVRNLIDVYYKK"
     gene            complement(5422..6492)
                     /locus_tag="ACL3EZ_001733"
     CDS             complement(5422..6492)
                     /locus_tag="ACL3EZ_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000401842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease"
                     /protein_id="HGR0393267.1"
                     /translation="MEIDKVKADLKQVGKRVADLSQSITNEEQTKNAFIMPFFQALGY
                     DIFNPLEFVPEFTADVGIKKGEKVDYAIILDGEPQILIECKSITENLTKHDSQLFRYF
                     VTTKSKFGILTNGREYKFFTDLDEPNKMDTTPFLTIDVTDIKENQFTEIIKFHKENFD
                     IDNIVSSASELKYLNNLKAFLTENITTPSDSFLRYLTSEIYEGRVTQNILTTFSPIIV
                     KGFNQFITERVNEKLSAALNTSVETKVTTDIPKVEAEAEEIVEVTDEIITTPAELEVY
                     TVVKMLARDVVSPERVFYRDNRSYFNVLVDDNIKKWVLRYRSNSKKSTIEIRDKGIFP
                     VSTPLEVANYANEILEVIKKFS"
     gene            complement(6509..6889)
                     /locus_tag="ACL3EZ_001734"
     CDS             complement(6509..6889)
                     /locus_tag="ACL3EZ_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HGR0393268.1"
                     /translation="MTLAKLCEEYQVELCLFDGSNWHNSGFYNPDTNVLAIDHNLTPE
                     QQIQVALHELGHKDHTRSEHQNARLRCENEADRNMIHHLVKDALENLDDPTEFDYLKF
                     MSYYNLKTMTNEIMVKEEYLALVN"
     gene            complement(6902..7165)
                     /locus_tag="ACL3EZ_001735"
     CDS             complement(6902..7165)
                     /locus_tag="ACL3EZ_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA];
                     GO_function: GO:0042803 - protein homodimerization
                     activity [Evidence IEA];
                     GO_process: GO:0030541 - plasmid partitioning [Evidence
                     IEA];
                     GO_process: GO:0051290 - protein heterotetramerization
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HGR0393269.1"
                     /translation="MYRLDIDKKALKQLKKLDTPTRKQILSWLAKNIENTTNPRQHGK
                     ALKANLAGYWRYRVENYRIICDIQDDKLVVLAVEIAHRRDVYK"
     gene            complement(7165..7398)
                     /locus_tag="ACL3EZ_001736"
     CDS             complement(7165..7398)
                     /locus_tag="ACL3EZ_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0393270.1"
                     /translation="MTITINFTEKNSYITDYLNKHGIDTTTMDFDDFMALMEDIEDAR
                     AADQAYMEYLADPATYTMDEVLDELGLTREDIA"
     gene            complement(7398..7766)
                     /locus_tag="ACL3EZ_001737"
     CDS             complement(7398..7766)
                     /locus_tag="ACL3EZ_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGR0393271.1"
                     /translation="MFETFEKIKELAKKRGKALGQVEEDLGYGRNTLYKIKNSTPNAE
                     RIAEIANYFNVSTDYLLGRTDNPAIAGSDEFAQVNGQIIDLRKAAANTMLFDGKPLNE
                     DDIDFITSVLSAHFKSKGER"
     gene            8338..8529
                     /locus_tag="ACL3EZ_001738"
     CDS             8338..8529
                     /locus_tag="ACL3EZ_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001112859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HGR0393272.1"
                     /translation="MPDIANGRERVIAFLKEKGIKKATLAVAYGFKRQEVTNILSGTT
                     KGPRANSFILQVIEDYGIE"
     gene            8552..8755
                     /locus_tag="ACL3EZ_001739"
     CDS             8552..8755
                     /locus_tag="ACL3EZ_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001247546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0393273.1"
                     /translation="MRPKRYPYSGQKESTFVKADPELVEKLLRNTSFLECLQKKPINF
                     QIDSEEFKRLSYEAIHDTSQVTQ"
     gene            complement(8910..9077)
                     /locus_tag="ACL3EZ_001740"
     CDS             complement(8910..9077)
                     /locus_tag="ACL3EZ_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjzC family protein"
                     /protein_id="HGR0393274.1"
                     /translation="MANTPIKPGTDNQKPGRYVEVGPRGGKVTNGHTATIGKGDRLPP
                     TSAKGNGWKKV"
     gene            9097..9462
                     /locus_tag="ACL3EZ_001741"
                     /pseudo
     CDS             9097..9462
                     /locus_tag="ACL3EZ_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="autolysin"
     gene            complement(9682..9861)
                     /locus_tag="ACL3EZ_001742"
     CDS             complement(9682..9861)
                     /locus_tag="ACL3EZ_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0393275.1"
                     /translation="MREVIQELLDSSMSTSAISQGAGVPWTTVSDLRKGKTSMDKMAL
                     LTAEKLYEFATTDKQ"
     gene            complement(10003..10152)
                     /locus_tag="ACL3EZ_001743"
     CDS             complement(10003..10152)
                     /locus_tag="ACL3EZ_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0393276.1"
                     /translation="MNKEDWLRLLEKAIDNIPETVTAIASLVTAITVARQNKKRKPKS
                     RQRKR"
     gene            10457..10900
                     /locus_tag="ACL3EZ_001744"
     CDS             10457..10900
                     /locus_tag="ACL3EZ_001744"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HGR0393277.1"
                     /translation="MKIRGFELVSSFTDENLLPKRETAHAAGYDLKVAVRTVVAPGEI
                     VLVPTGVKAYMQPTEVLYLYDRSSNPRKKGLVLINSVGVIDGDYYGNPGNEGHIFAQM
                     KNITDQEVVLEVGERIVQAVFATFLIADGDAADGVRTGGFGSTGH"
     gene            10902..11417
                     /locus_tag="ACL3EZ_001745"
     CDS             10902..11417
                     /locus_tag="ACL3EZ_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HGR0393278.1"
                     /translation="MKIIFVRHGEPDYRELEERSYIGFGIDLAPLSEMGRQQVQKLSK
                     NPLLSSAEIIVSSAVTRALETASYVVCATGLPLRVEPLLHEWQVYKTGIENFETARRL
                     FLENKGELLPNSPIQYETATEMKSRFLECMSKYREHQTVVVVAHRMLMRQFVPNEKID
                     FCQVIECELEI"
     gene            11431..12792
                     /gene="radA"
                     /locus_tag="ACL3EZ_001746"
     CDS             11431..12792
                     /gene="radA"
                     /locus_tag="ACL3EZ_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016893792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HGR0393279.1"
                     /translation="MAKKKATFVCQNCGYNSPKYLGRCPNCGSWSSFVEEVEVAEVKN
                     ARVSLTGEKTKPMKLAEVTSINVNRTKTEMEEFNRVLGGGVVPGSLVLIGGDPGIGKS
                     TLLLQVSTQLSQVGTVLYVSGEESAQQIKLRAERLGDIDSEFYLYAETNMQSVRAEVE
                     RIQPDFLIIDSIQTIMSPEISGVQGSVSQVREVTAELMQLAKTNNIAIFIVGHVTKEG
                     TLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNP
                     SQVFLEERLDGATGSSIVVTMEGTRPILAEVQALVTPTMFGNAKRTTTGLDFNRASLI
                     MAVLEKRAGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKDKPTNPQECFVGE
                     LGLTGEIRRVNRIEQRINEAAKLGFTKIYVPKNSLTGITLPKEIQVIGVTTIQEVLKK
                     VFA"
     gene            12865..13362
                     /locus_tag="ACL3EZ_001747"
     CDS             12865..13362
                     /locus_tag="ACL3EZ_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-class carbonic anhydrase"
                     /protein_id="HGR0393280.1"
                     /translation="MSYFEQFMQANQAYVALHGQLNLPLKPKTRVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRVTEDMIRSLVISQQQMGTREIVVLHHTDCGAQTFENEPF
                     QEYLKEELGVDVSDQDFLPFQDIEESVREDMQLLIESPLIPDDVIISGAIYNVDTGSM
                     AVVEL"
     gene            13387..14170
                     /locus_tag="ACL3EZ_001748"
                     /pseudo
     CDS             13387..14170
                     /locus_tag="ACL3EZ_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749763.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family glutamic-type intramembrane
                     protease"
     gene            14315..15283
                     /locus_tag="ACL3EZ_001749"
     CDS             14315..15283
                     /locus_tag="ACL3EZ_001749"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004749 - ribose phosphate diphosphokinase
                     activity [Evidence IEA];
                     GO_process: GO:0009156 - ribonucleoside monophosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HGR0393281.1"
                     /translation="MSFSDLKLFALSSNKELAERVAQEIGIELGKSSVRQFSDGEIQV
                     NIEESIRGKHVFILQSTSSPVNDNLLEILIMVDALKRASAESVNVVMPYYGYARQDRK
                     ARAREPITSKLVANMLEVAGVDRLLTIDLHAAQIQGFFDIPVDHLMGAPLIADYFERR
                     GMVGSDYVVVSPDHGGVTRARKLAEFLKTSIAIIDKRRSVDKMNTSEVMNIIGKVEGK
                     TCILIDDMIDTAGTICHAADALAEAGAVAVYASCTHPVLSGPATDNIQKSAIKKLVVL
                     DTIYLPEERLIDKIEQISIAHLLGDAIVRIHEKRPLSPLFDIEKKI"
BASE COUNT         4359 a         2552 c         3418 g         5162 t
ORIGIN      
        1 gccttatttc ttaaaaattt taatagttta aagcacctag cacctgttta gattgatgaa
       61 acaggattcg atacttattt ttatcgagaa tatggtcgct cattaaaagg tcagttaaga
      121 agaggtaaag tatctggaag aagatatcag aggatttctt tggttgcagg tctaacaaat
      181 ggtgagttaa tcgctccaat gacttacgaa gagatggtga cgagcgactt ttttgaagct
      241 tggtttcaga agtttctctt accaacatta accacaccat cggttattat tatggataat
      301 gcaagattcc atagaatggg taagttagaa cttttatgcg aggagtttgg gcataaactt
      361 ttacctcttc ctccctactc acctgagtac aatcctattg agaaaacatg ggcttatatc
      421 aaaaagaacc tcaaaaaggt attaccaagt tgcaatacct tttacgaggc tcttttctct
      481 tgttcttgtt tcaattgact atattagagg cgagacattt ttcggttctt tgtcaactgt
      541 agtgggttga agaaagcgaa gatctagaaa ggacaaattt cgtcctttct tttttgaagt
      601 tttcaaagtt cctaaaacca aaggcattgt gcttgataag tttgatgaga ttattggtgg
      661 cttccagttt ggcgttggaa taaggtaatt gaagggcgtt gacgattttc tctttatctt
      721 tgaggaaggt tttaaacaaa gtctgaaaca gaggtggaaa agcaagagct gatagagatt
      781 atagtggtgt ttcaagtctt cggaatagct caaaagttta tctagaattt ctttattagt
      841 caagtgcata cgaaaagtag ggcgataaaa tcgtttatca ctcagtttct gactatcttg
      901 ttgaatgagc ttccagtagc gcttgatagc cttgtattca tgggatttcg gatgatggct
      961 tgtgttctgc tctcaagaac agttatgata ttgagtttat caaagtcctg agcaataaag
     1021 ctcatctcca tctcccgatt gaaacagtca ctccccggac tgtttcaacg tcctaggaca
     1081 taatctcagg aagacgcgaa aaatcatgct caaagtgaaa attattgatc ttgcgaatga
     1141 cagttgaagt tgaaatagac aactgatgat caatgtcggt catagaaatc ttttcaatta
     1201 acttttgagc aatcttttgg ttgatgatac aaggaatttg atgattcttc ttgacgatag
     1261 aagtctcagc gagctccatt tttgagcaat gatagcactt aaaacggcct tttctaagaa
     1321 gaattctagt ttgaattttt ttatactaga aaatcagaac cataatacct atataaaaat
     1381 attatagttc taataggatt tacccaaaag ttttaaggcg gtctttttag aactttaatt
     1441 gtttgaaatt taggtagcaa atttgtttct attttgtcaa cttttcctat ttttatcttg
     1501 ttgaggctgg tattttaaca attcaggaat tgatagtgaa tgtgtaaaat tttttgttag
     1561 aataagttta taaaaaagaa aaggagtatt tgattatgtt acaaaaaatt tatgagcaga
     1621 tggctaattt ctatgatagt attgaagaag agtatggtcc tacatttggt gataattttg
     1681 actgggaaca tgttcatttt aaatttttaa tttattattt agtgagatat ggcattggtt
     1741 gtcataggga ttttatcgtt taccattatc gtgttgctta tcgtttgtat cttgaaaaat
     1801 tggtaatgaa tcggggtttt atttcttgtt gaggtaattt tagtaaattt ccgaactaat
     1861 ttactctttt atgtaaagat aatagtaaat agctagtaat ttttctaaat cattttttaa
     1921 tagttggaaa tagcaaatct ttctattgtt tcttcttgat aaaaaggcga ttttttatta
     1981 taataaattg taagatataa ttgcaggtga gagtcctgcc atgtatgtga gaaaggaaga
     2041 gcctgagggc tcagacaaaa ttatgacttc agttgttgtt gtaggtaccc aatggggtga
     2101 tgaaggtaaa gggaagatta cagacttcct ttcagcgaat gcagaagtga ttgcacgtta
     2161 ccaaggtggt gataatgctg gtcacacgat tgtgattgac ggtaagaaat ttaagttgca
     2221 cttgattcca tctgggattt tcttccctga aaaaatatct gtcattggga atggtatggt
     2281 tgtaaatcct aaatctcttg taaaagagtt gagctatctt catgaggaag gtgtaacaac
     2341 tgataacttg cgtatttctg atcgtgcgca tgttattttg ccttatcata tcgagttgga
     2401 tcgcttgcaa gaagaagcta agggcgacaa taagattggt acgacaatta agggaattgg
     2461 tccagcttat atggacaagg ctgctcgtgt tggaattcgt attgcagatc ttttagataa
     2521 agatattttc cgtgagcgtt tagaacgtaa ccttgctgaa aagaatcgtc tttttgaaaa
     2581 attgtatgac agtaaagcga ttgttttcga tgatattttt gaagaatatt acgaatatgg
     2641 tcaacaaatc aagaaatacg tgatagatac atctgttatc ttgaatgatg cgcttgataa
     2701 tggcaaacgt gtgctttttg aaggtgcaca aggtgttatg ctagatatcg accaaggtac
     2761 ttatccattt gttacgtcat caaaccctgt agctggtggt gtgacaattg gttctggtgt
     2821 cggtccaagc aagattgaca aggttgtagg tgtatgtaaa gcttatacga gtcgtgtagg
     2881 agatggtcct ttcccaactg agttgtttga tgaagtggga gaacgtatcc gtgaagtggg
     2941 tcatgagtat ggtacaacaa ctggtcgtcc acgtcgtgta ggttggtttg actcagttgt
     3001 gatgcgtcat agccgtcgtg tttctggtat tactaacctt tctttgaact ctattgatgt
     3061 tttgagcggt ttggatactg tgaaaatctg tgtggcctat gatcttgacg gtcaacgtat
     3121 tgactactat ccagctagtc ttgagcaatt gaaacgttgc aagcctatct atgaagagtt
     3181 gccaggttgg tcagaagata ttaccggagt tcgcaatttg gaagatcttc ctgagaatgc
     3241 gcgtaactat gttcgtcgtg tgagtgaatt ggttggcgtt cgtatttcta ctttctcagt
     3301 aggtcctggt cgtgaacaaa caaatatttt agaaagtgtt tggtcctaag agatttttaa
     3361 gatttgttta agataggtcg ggtatactat agacagttac aagaagacct cctaacttgt
     3421 tgtaacaaat atcctaaact tttctttttc ataataatct ccctatagag tcaccgcatt
     3481 cggtggcttc ttttgtgttg ggattcatga tataataata aaatcgataa gtaggaaaag
     3541 agaaaagaga tgtattatac gcttgaagaa aaagaagtct ttatgaggga ggctttgaga
     3601 gaggctgaga ttgctcttga acacgatgaa attccaattg gttgtgtgat tgtcaaagat
     3661 ggggaaatca ttggtcgtgg gcataatgcg cgtgaggaat tacagcgagc ggttatgcat
     3721 gcggaaatta tggctataga ggatgcgaac ttgagtgagg agagctggcg cttgctggat
     3781 tgcacacttt ttgtgaccat tgaaccttgt gtcatgtgta gtggggcgat tgggcttgcc
     3841 cgcattccaa atgtggtcta tggggctaaa aaccagaaat ttggcgctgc tgggagtttg
     3901 tacgatatct tgacagatga gcgtctcaat catcgtgtgg aggttgaaat aggaattttg
     3961 gaagatgaat gcgcagctat catgcaggat ttttttagaa atagacggaa aaaataattt
     4021 tgcttttaaa atgaatagga atgtgatata ataaatagtg gagcaacagt tctgcgtgaa
     4081 gcgggtcagg ggaggaatcc agcagcccta agcgatttga attgtgtgct cttttttcgt
     4141 gcactttaaa aaccctttaa aatcaacact ttaaggggtt tttgtttgtc ttgtataaga
     4201 aaaaggggca gacgaggggc acaatttaaa attttatctt atctaacttg ctagatatgt
     4261 ctgataccat tttttgagta acgtgagaat aaatctctag tgtggtcttt gagtcactat
     4321 gccctactct gtccatgatg gcagtcaagg gaatgcccag ctcagcaagt agggatatgt
     4381 gagaatgtct aaatgtatgt gtagttatgt ttttttctat gccgattttt tgaccatgtc
     4441 ttttcaatgc acaaataacc ctggcatttg ttattggttc tcctagagta ttgatgaaaa
     4501 taaaatctgt atcaaatcca tttgtcgcat tctctattat ttgctctttg ataatatcta
     4561 acactttttg aggtgctgtt ataaccctat cggacttgat tgtctttggt gtagttctct
     4621 ctttttgtct gaaatcgtat gtatgcttga tgtgaatagt ctttttagaa aaatctatat
     4681 cttccttgta gtttaaggct gccagctctc catacctcat gccagtaaga aaaagaactt
     4741 tagctattcg gatatacttt gtaattcgat aatcacatag ggcctcgtct tttaaatttt
     4801 ggatgaataa cttaaactct ttttggtcta agtattttgt atttttcttt ctgagttcgt
     4861 cggatgtaat tacttttcta ggcgtttcaa caaatagcat ttcatttgta tcaatataat
     4921 tcattctgat agcaaatttc attatctgat tgagcttgaa tttgatttta gaaacatagt
     4981 tatgagatct cccatcttgt aatagttgat ctattacttt ttgtaataaa cgtctatcaa
     5041 atttctaact aggtagtcgc cctctatctg ctttaaaatc tcttttttta cattctttga
     5101 agcgtagacg gttgagtttt ttacgccgtg tttccaattc tcctcaaatt cttcatatag
     5161 tttttcaaaa gttatattag aaacagaatg ttgtttttct cctaactttt gttttatctt
     5221 ttcctgaagt aaaatcgcag cttgatttct tgcttgggga gtttttttct ccatcgttac
     5281 tgagactttt tttaatttct cagtatatgg atctttgtat ctctcaaaaa atttatattt
     5341 gccgtttggc aattcttcca tccacattga ttttacctca cttttttgat aaaatgggta
     5401 tagtaaagag ggcttttttt attatgagaa tttcttgatt acttctaaaa tttcattggc
     5461 ataatttgcg acttcgagag gggtagacac cgggaagatg cctttatcac ggatttcgat
     5521 agtgcttttt tttgaatttg aacgataacg taatacccat tttttgatgt tatcgtcaac
     5581 caaaacattg aaatagctac ggttatctct gtaaaataca cgttctggag aaactacatc
     5641 cctagcaagc attttaacaa cagtataaac ttctaattca gcaggagttg tgataatttc
     5701 gtcagttact tcgacaatct cttcagcttc agcttcaact tttggaatat cggttgttac
     5761 tttggtttca acgcttgtat taagtgcagc acttaatttt tcattaactc gctctgtgat
     5821 gaattgatta aaccctttca caataatggg agaaaatgtc gttaagatat tttgagtaac
     5881 acgcccttca tagatttcag aagttagata tctgaggaag ctatctgacg gtgtagtgat
     5941 attttcagta aggaacgctt taagattgtt gaggtatttc aattcagaag ctgatgaaac
     6001 aatattatca atatcaaaat tctctttgtg gaatttgatg atttcagtaa attgattttc
     6061 tttgatatca gtcacatcga ttgttaagaa tggagttgtg tccattttat ttggctcatc
     6121 taaatcagta aagaatttat attctctacc atttgtcaag ataccgaatt ttgatttagt
     6181 agttacgaaa tatctgaata gttgagagtc gtgcttagta aggttttctg taattgattt
     6241 acattcaatt aggatttgag gctcgccatc caaaatgatc gcatagtcga ctttttcgcc
     6301 ttttttaatg cccacgtcgg cagtaaattc cgggacaaat tcaagtggat tgaagatatc
     6361 atatccaagc gcttggaaga acggcataat gaaggcattc tttgtttgtt cttcattcgt
     6421 aatgctttgg ctgaggtctg ctacacgttt gccgacttgt tttaaatcgg cttttacttt
     6481 atcaatttcc atattgatac tccttttttt aatttactaa tgctaaatac tcttctttaa
     6541 ccatgatttc atttgtcatg gtttttagat tgtagtaaga catgaatttg aggtaatcaa
     6601 actctgtggg gtcgtctaag ttttctagag cgtcttttac gagatgatgg atcatattcc
     6661 tatcagcttc gttttcacag cgtagacggg cgttctggtg ctctgagcgt gtgtggtctt
     6721 tgtgtccaag ttcgtgtagg gcgacttgga tttgttgttc aggagtcaag ttgtggtcaa
     6781 tagcgagcac gtttgtgtct ggattgtaga aaccgctatt gtgccagttt gaaccgtcga
     6841 agagacaaag ttctacttga tattcttcgc agagtttagc gagtgtcata gttctccttc
     6901 gttatttata gacatctctg cggtgggcga tttccacggc taggacgact agtttatcgt
     6961 cttggatatc acagatgatg cggtaattct ctactctgta tcgccagtaa cctgcaaggt
     7021 tggcttttag tgcttttccg tgttgtcgtg gattggtcgt gttttcaatg tttttagcaa
     7081 gccaggatag gatttgtttt ctggttgggg tatctagttt tttaagttgc ttgagagctt
     7141 ttttatcaat atctagccga tacattaagc aatatcctct cgagttagtc ctagttcatc
     7201 caagacctca tccatggtat aagtagctgg gtcggctaaa tactccatat aggcttggtc
     7261 ggctgctcgt gcgtcttcga tatcttccat gagtgccatg aagtcgtcaa aatccatggt
     7321 cgttgtgtcg ataccgtgtt tgtttaggta gtccgtaatg taggaatttt tttctgtgaa
     7381 gttgatagtg atagtcatta gcgttctcct ttgcttttga agtgggcgga taggacggat
     7441 gtaatgaagt cgatatcatc ttcatttagt ggtttcccgt caaataacat ggtgttggct
     7501 gctgctttgc gtaagtctat gatttgtccg tttacttggg caaattcatc actcccagcg
     7561 atagcagggt tatctgttcg tccgagcagg tagtcggtgg atacgttgaa ataattagca
     7621 atttctgcga tacgttcagc gtttggcgta gaatttttta tcttatagag tgtatttcta
     7681 ccataaccta agtcttcttc tacttgtcca agagcttttc cacgcttttt tgccaattct
     7741 tttatttttt caaatgtctc aaacattgtt aaatcaacct ttctaagaca tcacaaaaaa
     7801 aatttaacaa atttggtgta aaaaggttga ctaattatcc caaaaggtgt aaaatgtttt
     7861 ttgtaagtga taaacaacta aaaaaacaac taagaaataa attataaaaa tgttttggcg
     7921 aacggtattt atagatttat tggtgttttt attatgcttt aattttagcc gatttggtgt
     7981 aagttgtcaa gtataatgca gaaaaatagt tacattttta gttgtttctt atttacaaat
     8041 aagtaaagag gaggaacgtg ctgatggtaa gtattcttaa aaatttagaa caagaaaaag
     8101 accaccttga aaaagtcatt aaggtagtca gcgctggtgg taaatttctg agattgccat
     8161 atcaaaaaag tcacgctcga ttagtgagaa tctgaaattg atttctcaaa atctttacca
     8221 tcatcgtaga tgtcgcgttt gcttgctttg agtaaatatt ctttaaaagt cataaggtta
     8281 actcctttct gcttatatta tagcagaaaa agaagaaaga aaaagaaagg agaaaatatg
     8341 ccagatatcg caaacggtcg cgaaagagtt attgctttct tgaaagagaa aggcattaaa
     8401 aaagcaactc tagcggttgc ttacggcttt aaacgacagg aagtgacaaa cattctaagt
     8461 ggaacgacta aaggtccacg agcgaacagt ttcattcttc aggttattga agattatggg
     8521 attgagtagg aaagatttga ggagtaggaa aatgagacca aaacgatatc cgtatagtgg
     8581 acaaaaagag tccacctttg taaaggcaga ccctgagtta gttgaaaaac ttttaagaaa
     8641 cactagtttt cttgagtgtt tacaaaaaaa gcctatcaat tttcagatag actcagaaga
     8701 atttaagcgt cttagctatg aagccattca tgatacttct caagtaactc aataggagga
     8761 aggaataaaa tgattcacca ttatataact cactatgcca gcaatgggaa agattacgcc
     8821 gaagcatgga ttcaaattga ttttttggga atgtgctttt gtgtatggaa aaagcgtaca
     8881 accattgaac gattgtacgc aaacgaagat tagacttttt tccaaccgtt gcctttagca
     8941 gatgtcggag ggagccgatc accttttccg atagttgcgg tatgaccatt agtaactttt
     9001 ccgccacgag gtcctacctc tacatagcga ccaggtttct gattatctgt tccaggtttt
     9061 attggagtat ttgccatact atctcctcct ttctataagt ttgagaaaat caacggtatc
     9121 tggtattatt tcgatggctc aggctatatg ctttcagacc gctggaagaa gcacacagac
     9181 ggtaattggt actactttga ccaatcaggc gaaatggcca caggctggaa gaaaatcgct
     9241 gacaagtggt actattttga tgtagaaggt gccatgaaga caggctgggt caagtacaag
     9301 gacacttggt actacttaga cgctaaagaa ggcgccatgg tatcaaatgc ctttatccag
     9361 tcagcggacg gaacaggctg gtactacctc aaaccagacg gaacactggc agacaagcca
     9421 gagttcacag tagagccaga tggcttgatt acagttaaat aaatagaaag gaaactttct
     9481 aaattgttct ttcaccgcag gctcaggctt gcggtttttt atttgctctg attcttcaaa
     9541 aaagcgtttt cttgaagaat agggaggagg aatggcaggg tattattgcc aaaaacgcca
     9601 ttttgttaat aatagctcct ttttattttt tgattattgt caaaaacggt gttttgtcaa
     9661 aaataaaaac agtgaccgaa atcactgctt atcagttgta gcaaattcat aaagtttttc
     9721 tgctgtgaga agtgccattt tgtccatgct tgtttttcct tttctgaggt cagaaacagt
     9781 agtccatgga actccagcac cttgggaaat agcagatgta gacatcgaac tgtctaacaa
     9841 ttcttgaata acttctctca tcttatttgt cctttttatt ttttagataa atatatacat
     9901 tgaccgcaat tataaaaata gctattgcac taaccattgc ttttcctctt ttcatttgat
     9961 aaaatagagg tgtgaggggc tttcgcccca acctcttagc gttcaccttt ttctttgacg
    10021 ggatttcggt ttacgctttt tgttttgcct tgcgaccgtt attgcagtca ccagacttgc
    10081 tatagcagtt accgtttcag ggatattatc tatcgccttt tccagtaacc taagccaatc
    10141 ttctttgttc aacttcctca cctcctttcc ttatcttgat tatattatat cacggtaaac
    10201 cgtgaaagtc aagcgatttg atgaagtttt tttgaaaaac aaaggggcaa aaaaggggca
    10261 aaagtgtcgt aaacctctgt aaaacgatgt aaaaaatcaa ctttgccctc gctttaaagc
    10321 tctaaatttc aacgtattgt gaaacagtgt aaattatcgt atcgcctata attgttgtgt
    10381 gctctttttt tcgtgctttt tccgaataaa taagatagaa taatctagaa taaatgataa
    10441 tagaaaagag aaaattatga aaattcgtgg ttttgaattg gtttcgagtt ttacagatga
    10501 aaatttattg cccaagcgtg agacagcgca tgcggctggt tacgacttaa aggttgctgt
    10561 gcgtacagtt gttgcgccag gagagattgt cttggttccg acaggggtta aggcttatat
    10621 gcagccgact gaggttctct acctctatga tcgttcttca aatcctcgta agaagggctt
    10681 ggttttaatt aactcagttg gggtcattga tggggattat tatggaaatc ctggaaatga
    10741 agggcatatt tttgcgcaga tgaagaatat cacagatcaa gaggttgttc ttgaagttgg
    10801 ggaacgtatt gtccaggctg tttttgctac tttcttaatt gcagatggag atgcagctga
    10861 tggcgttcga actggtggat ttggatcgac agggcactag aatgaagatt atctttgtac
    10921 gtcatgggga gccagattac cgtgagttag aggagcgttc ttatatagga tttgggatag
    10981 atttggcacc cttgtctgag atgggacggc agcaagtcca gaaattgagc aaaaatcctt
    11041 tactctcgtc agctgaaata atcgtatctt ctgcagtcac aagagcttta gaaacggctt
    11101 cgtatgtggt ctgtgctacg ggtcttcctt taagagtaga gcctttatta catgaatggc
    11161 aggtctataa aacaggaata gaaaactttg aaacagctag aagactgttt ttagaaaaca
    11221 agggggagtt gcttcctaat agtcctattc aatatgagac agctacggaa atgaagtctc
    11281 ggtttctaga atgtatgtct aagtatcgag aacatcagac tgtggtagtt gttgctcatc
    11341 gaatgctcat gcgccagttt gtgccaaatg agaagattga tttttgccaa gtgattgagt
    11401 gtgagttaga gatatagaaa gaggtttgtc atcgcaaaga aaaaagcgac atttgtatgt
    11461 caaaattgtg ggtataattc ccctaaatat ctgggacgtt gccccaactg tgggtcttgg
    11521 tcttcttttg tggaagaggt tgaggttgcc gaggtcaaga atgcgcgtgt gtccttgaca
    11581 ggtgagaaaa ccaagcccat gaaactagct gaggtgactt ccatcaatgt caatcgaacc
    11641 aagacggaga tggaggaatt caaccgtgtg cttggaggcg gagtggtacc aggaagtctc
    11701 gtcctcatcg gtggggatcc tgggattggg aaatcaactc ttctcctaca agtctcaacc
    11761 cagttgtccc aagtggggac agttctctat gtcagtgggg aggagtctgc ccagcagatt
    11821 aaactacgtg cagagcgctt aggtgatatt gatagtgagt tttatctcta tgcagagacc
    11881 aatatgcaga gtgttcgtgc agaagtggag cgtatccagc cagactttct cattattgat
    11941 tccatccaga ccatcatgtc tcctgagatt tcaggggtgc aggggtctgt ttctcaggta
    12001 cgtgaagtga ccgctgaact catgcagttg gccaagacca ataacattgc catctttatc
    12061 gtaggtcatg tgaccaaaga aggaaccttg gctgggcctc gtatgttgga gcatatggtg
    12121 gatacggtgc tttactttga aggggagcgt caccacacct ttcgtatttt gagagcggtc
    12181 aaaaatcgtt ttggttccac taatgagatt gggatttttg agatgcagtc gggcggcttg
    12241 gttgaggtac tcaatccgag tcaagttttc ctagaagagc gtttggatgg ggcgactggt
    12301 tcctccatcg ttgtaaccat ggaagggacg cgtccgattt tggcggaggt tcaggctttg
    12361 gtaacaccga ccatgtttgg aaatgccaag cgtactacga caggacttga ttttaaccgt
    12421 gctagcttga ttatggctgt tttggaaaaa cgggcagggc ttctcttgca aaatcaggat
    12481 gcctatctca aatctgctgg tggtgttaaa ttggatgaac ctgcgattga cttggctgtt
    12541 gcagttgcta ttgcttcgag ctacaaagac aagccaacta atcctcagga atgttttgtc
    12601 ggagaactgg gcttgacagg agagattcgg cgcgtgaatc gtattgagca acgcatcaac
    12661 gaagctgcta aactgggctt tactaagatt tatgtaccta agaattcctt gacaggaatc
    12721 actctgccta aggaaattca ggtcattggc gtgacaacga ttcaggaagt cttgaaaaag
    12781 gtctttgcat aatccgtgac aaattctctt aaaaatgata agataggaga aatatttgac
    12841 tatcaaattt tcaaggaggg aatcgtgtcg tattttgaac agtttatgca agccaatcag
    12901 gcttatgttg ccctacatgg gcagttaaat ctgccactta aacctaaaac cagagtagcc
    12961 attgtgacct gtatggactc acgtttgcac gttgcgcaag ctctaggttt ggcacttggg
    13021 gatgctcata ttttgcggaa tgcaggtggt cgagtgactg aggatatgat tcgttctcta
    13081 gttatttccc agcaacaaat ggggacaaga gaaattgtgg tattgcatca tacagactgt
    13141 ggtgctcaga cctttgaaaa tgaacctttt caggagtatt tgaaggaaga attgggtgtc
    13201 gatgtgtcag accaggactt cttgcccttc caagatatag aagagagtgt acgcgaggat
    13261 atgcaactgc ttatcgagtc tcccctaata ccagacgatg tcattatctc tggtgccatt
    13321 tacaatgttg atacaggaag tatggcagtc gtagaattat aaatacttca tttagaaaga
    13381 aagtgtatga agaaaagcag tattttattt atttttattt tattgctatg tattggttta
    13441 cagtatgaaa ccatctacta tacggacggt tcgaggtcag gtgcggaata tggactaatg
    13501 ggagtttcta tctttctagc tctcttttac atgattccgg ctctttattt tctcttccgt
    13561 attgggaaaa aatgggaatt gccaaagaag gttttgattc tgtctttatt gggagggatg
    13621 ttccttttag gctggttgtc tagttttgct aatacttata tccatgattt actgggggtt
    13681 cttttcccag atagtccatt tttaaatgcc tttgaaagtg ctattgtggc tcctttggta
    13741 gaagaaccct tgaaattatt gccacttgtt tttgttttgg ctttgattcc tgtgcgaaaa
    13801 ttaaaatttt tgtttttact tggaattgcc tccggtttgg gattccaaat gattgaggat
    13861 attggttata ttcgtacgga tttgccagag ggctttgact ttactatttc gcgaatttta
    13921 gagcgtatca tctcaggaat tgcctctcac tggacttttt caggtctagc tgtagtaggt
    13981 gtttacttgc tttacagagc ctataaagga cagaaggttg gcaagaaaca gggtcttatt
    14041 gtttaactct ccttttgtgg agttggaaac agagttgcct ttagcgattc cagtggttac
    14101 ggctattgct ctctatggtt attatcatgc ttattgcttt gttgagaaac acaatgagtt
    14161 gatgacctag aatatttttc aaaagaatga tgcaagggta caaatatggt gcccttcttt
    14221 tatttttgat tgaaaaatag tgcaaaaagc gctacaatgg tagatggaaa atcttgtgaa
    14281 aagcacaagc gatacatata taccggagga aatcatgtct ttttctgatt taaagctgtt
    14341 tgccctttct tctaataaag aattggcaga acgtgtggcg caggagattg ggatagagtt
    14401 ggggaaatca agtgttcgcc aattttcaga tggagagatt caggtcaaca ttgaagaatc
    14461 aatccgtggg aaacacgtct ttatcttaca atcaactagt tcgcctgtaa atgacaatct
    14521 gcttgaaatt ttgattatgg tagatgcttt gaagcgtgcg agtgcagagt ctgtcaatgt
    14581 tgtcatgcct tactatgggt atgcacgtca ggatagaaag gcgagagcgc gtgagccaat
    14641 cacttcaaaa cttgtcgcaa atatgcttga agtagctgga gtggatcgtt tattgaccat
    14701 cgacttgcat gctgcgcaaa ttcaaggatt ctttgatatt cctgtggatc atttgatggg
    14761 tgctcctcta attgcagatt attttgagcg gcgtggtatg gttggttctg actatgtggt
    14821 tgtcagcccg gaccatggag gggtgactcg tgctcgtaag ttggcagaat ttttgaaaac
    14881 atctatcgct attattgata aacgtcgtag cgttgataag atgaatacta gtgaagttat
    14941 gaacatcatc ggtaaggttg aaggcaagac ttgtatcttg attgatgata tgattgatac
    15001 cgctggaacg atttgtcatg cggcagatgc tcttgcggaa gctggtgctg ttgcagtcta
    15061 tgcaagctgt acgcacccag ttctttctgg tcctgctacg gacaatatcc aaaaatcagc
    15121 tattaagaaa ttggttgttt tggataccat ctatctgcca gaagagcgtt tgattgataa
    15181 gattgagcag atttcaatcg ctcatctcct aggggatgct atcgtacgta ttcatgaaaa
    15241 acgaccactt tctccacttt tcgatattga gaaaaaaatt taatgaccaa gcctgagatg
    15301 attctcaggt tttttcgtct tttttccgaa taaatggata gtagcggtga atctagtaaa
    15361 gctagattta aaactgtgat ataataaaaa gagaagaaat atgactatac gtcatcagaa
    15421 gtttcagcga ccatcatttt tgaacagtga tagcacttga atcgacgctt tctaaggaga
    15481 attctagtag g
//
LOCUS       DBEJHE010000038        15050 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC4 isolate 671759
            SAMN38261586-rid24793303.denovo.38, whole genome shotgun sequence.
ACCESSION   DBEJHE010000038 DBEJHE010000000
VERSION     DBEJHE010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261586
            Sequence Read Archive: SRR26833752
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 15050)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15050)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576136.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576136.1
            Genome Coverage       :: 109x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 19:48:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,067
            CDSs (total)                      :: 2,029
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 131
            CDSs (without protein)            :: 131
            Pseudo Genes (ambiguous residues) :: 0 of 131
            Pseudo Genes (frameshifted)       :: 64 of 131
            Pseudo Genes (incomplete)         :: 59 of 131
            Pseudo Genes (internal stop)      :: 46 of 131
            Pseudo Genes (multiple problems)  :: 32 of 131
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15050
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261586-rid24793303.denovo.38"
                     /strain="GPSC4"
                     /isolate="671759"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            83..880
                     /locus_tag="ACL3EZ_001750"
     CDS             83..880
                     /locus_tag="ACL3EZ_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015499 - formate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015724 - formate transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HGR0393282.1"
                     /translation="MVSSEFISKIEFACNKKESLYSQSKFKYAIRSMFAGAFLTFSTA
                     AGAVGADLINKIAPGSGRFLFPFVFAWGLAYIVFLNAELVTSNMMFLTAGSFLKKISW
                     RKTAEILLYCTLFNLIGALIAGWGFAHSAAYANLTHDSFISGVVEMKLGRSNELVLLE
                     AILANIFVNIAILSFILVKDGGAKLWLVLSAIYMFVFLTNEHIAANFASFAIVKFSVA
                     ADSIANFGVGNMLRHWGVTFIGNFIGGGLLMGLPYAFLNKNEDTYVD"
     gene            1079..2287
                     /locus_tag="ACL3EZ_001751"
                     /pseudo
     CDS             1079..2287
                     /locus_tag="ACL3EZ_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365067.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0019346 - transsulfuration [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase family
                     protein"
     gene            2383..3657
                     /locus_tag="ACL3EZ_001752"
     CDS             2383..3657
                     /locus_tag="ACL3EZ_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2130 domain-containing protein"
                     /protein_id="HGR0393283.1"
                     /translation="MNEIKCPNCGEVFTVNESQYAELLSQVRTAEFDKELHDRMRQEL
                     ALAEQKAMNEQQTKLAQKDQEIAQLQSQIQNFDTEKELAKKEVEQTSHQALLAKDKEV
                     QALENQLATLRLEHENQLQKTLSDLEKERNQVKNQLLLQDKENELSLASVKQNYEAQL
                     KAASEQVEFYKNFKAQQSTKAIGESLEHYAESEFNKVRSFAFPNAYFEKDNKVSSRGS
                     KGDFIFRECDENGVEIISIMFEMKNEADGTEKKHKNADFYKELDKDRREKNCEYAVLV
                     TMLEADNDYFNTGIVDVSHEYEKMYVVRPQFFIQLIGLLRNAALNSLKYKQELALVRE
                     QNIDITHFEEDLDAFKLAFAKNYNSASTNFGKAIDEIDKAIKRMEEVKKFLTTSENQL
                     RLANNKLEDVSVKKLTRKNPTMKAKFEALKGE"
     gene            3667..4545
                     /gene="truB"
                     /locus_tag="ACL3EZ_001753"
     CDS             3667..4545
                     /gene="truB"
                     /locus_tag="ACL3EZ_001753"
                     /EC_number="5.4.99.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HGR0393284.1"
                     /translation="MNGIINLKKEAGITSHDAVFKLRKILGTKKIGHGGTLDPDVVGV
                     LPIAVGKATRMVEFMQDEGKIYEGEITLGYSTTTEDASGEVIAETPVLSPLDEKLVDE
                     AIASLTGPITQIPPMYSAVKVNGRKLYEYARAGQEVERPERQVTIYQFERTSPISYDG
                     QLARFTFRVKCSKGTYIRTLSVDLGEKLGYAAHMSHLTRTSAAGLQLEDALALEEIAE
                     KVEAGQLDFLHPLEIGTGDLVKVFLTPEEATEVRFGRFIELDQTDKELAAFEDDKLLA
                     ILEKRGNLYKPRKVFS"
     gene            4806..5108
                     /locus_tag="ACL3EZ_001754"
     CDS             4806..5108
                     /locus_tag="ACL3EZ_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HGR0393285.1"
                     /translation="MMRNEFRERVEQLLQQKEINENSELSHLFRLAIQNLDRNEKYQT
                     VMANLSQGLSLYFMTHHYQAPKSVIDFGLWIAKAPSQERGRLAFLQMLAQTLQGFR"
     gene            5216..5854
                     /gene="udk"
                     /locus_tag="ACL3EZ_001755"
     CDS             5216..5854
                     /gene="udk"
                     /locus_tag="ACL3EZ_001755"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004849 - uridine kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HGR0393286.1"
                     /translation="MQNRPIIIGVTGGSGGGKTSVSRAILSHFPDEKISMIEHDSYYK
                     DQSHLTFEERVKTNYDHPFAFDTDLMIEQIKELLAGRPVDIPTYDYTEHTRSSKTYRQ
                     EPQDVFIVEGILVLEDKRLRDLMDIKIFVDTDDDVRIIRRIKRDMEERGRSLDSVINQ
                     YLGVVKPMYHQFIESTKRYADIVIPEGVSNTVAIDLLTTKIAKILEEARNSK"
     gene            5982..7322
                     /gene="xseA"
                     /locus_tag="ACL3EZ_001756"
     CDS             5982..7322
                     /gene="xseA"
                     /locus_tag="ACL3EZ_001756"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA];
                     GO_function: GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA];
                     GO_process: GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HGR0393287.1"
                     /translation="MEKYLSVTTLTKYLKMKFDKDPYLERVYLTGQVSNFRKRPTHQY
                     FSLKDDHAVIQATIWSGIYQKLGFDLEEGMKINVIGRVQVYEPSGSYSIIIEKAEPDG
                     VGALAIQFEQLKKKLTEEGLFQERFKQALPQFSKRIGVVTSRSGAVIRDIITTVSRRF
                     PGVDILLYPTKVQGEGAAEEIARNIARANQRDDLDLLIIGRGGGSIEDLWAFNEEIVV
                     RAIFESRLPVISSVGHETDVTLADFVADRRAATPTAAAELATPVTKLDVLTHLQNQEK
                     RMATAVRNVLSKKQEALKKCSQSVIFRQPERLYDGYLQRLDQLQLRLKQSLRTRISDN
                     KQLVQARTHQLVQLSPVTKIQRYQDRLGQLDKLLGSQMALVYDAKVAEAKRLSEALLM
                     LDTSRIVARGYAIVKKEESIVDSVESLKKKDQVTLLMRDGQVELEVKDVKTKEI"
     gene            7300..7512
                     /locus_tag="ACL3EZ_001757"
     CDS             7300..7512
                     /locus_tag="ACL3EZ_001757"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HGR0393288.1"
                     /translation="MSKQKKFEENLAELETIVQSLENGEIALEDAITAFQKGMVLSKE
                     LQATLDKAEKTLVKVMQEDGTESDFE"
     gene            7509..8384
                     /locus_tag="ACL3EZ_001758"
     CDS             7509..8384
                     /locus_tag="ACL3EZ_001758"
                     /EC_number="2.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004659 - prenyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HGR0393289.1"
                     /translation="MKKQEKLALVESALEDFYGDQQFASSLRESVLYSIHAGGKRIRP
                     FLLLEVLEALQVTIKPAHAQVATALEMIHTGSLIHDDLPAMDDDDYRRGRLTNHKKFG
                     EAMAILAGDALFLDPYALIAQADLPSQIKVDLIANLSLASGSLGMVAGQVLDMEGEHQ
                     HLSLEELQIIHANKTGKLLAYPFQAAAIIAELSPEMQVKLKTVGELIGLAFQVRDDVL
                     DVTASFEEIGKTPQKDLQAEKSTYPALLGLEESIAFCNQTLDQANEKLEEIAQQLPFE
                     TESIVSVVESLRING"
     gene            8377..9192
                     /locus_tag="ACL3EZ_001759"
     CDS             8377..9192
                     /locus_tag="ACL3EZ_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HGR0393290.1"
                     /translation="MAKERVDVLAYKQGLFETREQAKRGVMAGLVVAVLNGERFDKPG
                     EKIPDDTELKLKGEKLKYVSRGGLKLEKALQVFDLSVDGATTIDIGASTGGFTDVMLQ
                     NSAKLVFAVDVGTNQLAWKLRQDPRVVSMEQFNFRYAEKTDFEQEPSFASIDVSFISL
                     SLILPALHRVLADQGQVVALVKPQFEAGREQIGKNGIIRDAKIHQNVLESVTAMAVEA
                     GFSVLGLDFSPIQGGHGNIEFLAYLKKEKSASNQIFAEIKEAVERAHSQFKNE"
     gene            9185..9616
                     /locus_tag="ACL3EZ_001760"
     CDS             9185..9616
                     /locus_tag="ACL3EZ_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001034407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HGR0393291.1"
                     /translation="MNKKERLEKIRRLVTDYQIGTQEEIVEHLKEAGITATQATVSRD
                     IKELGIVKIPLRDNTYVYELPKSIVKSLQLAEDNIESAELMDKMINLQVIPGNTAFVK
                     AQLIDTFADKIFSCLTDNSSILVIARSGSLAEEIFEQVKNW"
     gene            9623..11290
                     /gene="recN"
                     /locus_tag="ACL3EZ_001761"
     CDS             9623..11290
                     /gene="recN"
                     /locus_tag="ACL3EZ_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HGR0393292.1"
                     /translation="MLLEISIKNFAIIEAISLNFEKGMTVLTGETGAGKSIIIDAMNM
                     MLGARATTDVIRHGAPKAEIEGLFSVENSRLLQEIFDEQGLELGDEIIIRREILQNGR
                     SISRVNGQMVNLSVLRAIGQHLVDIHGQHDHEELMRPQLHIQMLDEFGDAAFWDLKET
                     YQTSFDAYRKMRKQVLEVKKNQQEHKERIEMLEFQMAEIEAANLQAGEDLALNQERDK
                     LLNHKNIADTLTNAYSMLDNEDFSSLANVRSAMNDMESVEEYDPEYREISSSLSETYY
                     VLEDISKRLEAIIEDLDFDGNRLMQVENRLDLLHTITRKYGGTVDDVLLYFAKITEEY
                     NLLTGNNLSSEDMEAELKKLEVNLVNLAGQLASARHNLAQQLEAEIKQELQDLYMEKA
                     QFQVHFSKGKFSRGGNEMVEFYISTNPGEDFKPLVKVASGGELSRLMLAIKSAFSRKE
                     GKTSIVFDEVDTGVSGRVAQAIAQKIHKIGQHGQVLAISHLPQVIAIADYQFFIEKIS
                     NDHSTVSTVRLLTVEERVEEVAKMLAGDDVTEAALTQARELLRNREK"
     gene            11292..12020
                     /locus_tag="ACL3EZ_001762"
     CDS             11292..12020
                     /locus_tag="ACL3EZ_001762"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000133310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HGR0393293.1"
                     /translation="MTDYYVIGDVHGKAGMLEDLLKTWDGQTQLLFLGDLIDRGEDSH
                     RVLEMVKDLVDNQGAICLSGNHEYMFLTWLDDPEESYDHYRRNGGDTTINSILGRPLD
                     APVDGVEDAKRVAAEASDLVEFIRQMPFVVETDKYIFVHAGIDLTLDDWHETTDYKKV
                     WLRKPFHGAENHTGKTIVFGHTPVYGLLQQERGTSELWTTEDGKIGMDGGAVYGGVLH
                     GIVFTDQGMTEHHFIENDGFVAED"
     gene            12099..13922
                     /gene="lepA"
                     /locus_tag="ACL3EZ_001763"
     CDS             12099..13922
                     /gene="lepA"
                     /locus_tag="ACL3EZ_001763"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001047203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation elongation factor 4"
                     /protein_id="HGR0393294.1"
                     /translation="MNLEELKKRQGKIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMDLERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAILVVDAAQGIEAQTLANVYLALDNDLEIMPIINKIDLPAADPESVRTEIEDVI
                     GLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVTAPLKALIFDSVYDAYRGVILQ
                     VRVMDGVVKPGDKIQLMSNSKTFDVAEVGIFTPKAVGRDFLATGDVGYIAASIKTVQD
                     TRVGDTVTLATNPAAEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQ
                     FEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVIYKVNLTDGESMD
                     VSNPSEFPDPTKIATIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVN
                     VIYQIPLAEIVFDFFDKLKSSTRGYASFDYELSEYRPSKLVKMDILLNGDKVDALSFI
                     VHKDFAYERGKLIVDKLKKIIPRQQFEVPIQAAIGHKIVARTDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKAGKKRMKSIGSVEVPQEAFLSVLSMDEE"
     gene            complement(14003..14245)
                     /locus_tag="ACL3EZ_001764"
     CDS             complement(14003..14245)
                     /locus_tag="ACL3EZ_001764"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0393295.1"
                     /translation="MKIKEQTRKLAAGYSKHSFEVVDETDEVSSKHGFEVVDETDEVS
                     SKHGFEIVDETDEVSNHTYGKATLTWFEEIFEEYKN"
     gene            14425..14900
                     /locus_tag="ACL3EZ_001765"
                     /pseudo
     CDS             14425..14900
                     /locus_tag="ACL3EZ_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
     gene            14938..>15050
                     /locus_tag="ACL3EZ_001766"
     CDS             14938..>15050
                     /locus_tag="ACL3EZ_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HGR0393296.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHCDAV"
BASE COUNT         4497 a         2720 c         3526 g         4307 t
ORIGIN      
        1 acttttatga aatatagaaa acgcttccta aaacctaaag tttgtgatat aattatcaag
       61 aaaaaagatt taggagttta ttatggtttc ttcagaattt atctcaaaga ttgaatttgc
      121 ttgcaataag aaagaaagtc tttatagtca aagcaaattt aagtatgcga ttcgttcgat
      181 gttcgcaggt gcatttttaa ccttcagtac tgctgcaggt gcagttgggg ctgacttgat
      241 taataaaatt gcaccaggta gtggacgctt cctctttcca ttcgtttttg cttggggctt
      301 ggcctacatt gtttttttga atgccgagtt ggtcacttca aacatgatgt tcttgactgc
      361 tggtagtttc ttaaaaaaaa tctcttggag aaaaacagct gagattttac tatactgtac
      421 cttgttcaac cttatcggag ccttgatagc agggtggggc tttgctcatt cggcagccta
      481 tgcgaatctg acacacgata gtttcatctc aggtgttgtt gagatgaagt taggccgctc
      541 aaatgaattg gtcttgcttg aggcgatttt ggcaaatatt ttcgtaaata ttgcgattct
      601 gtcatttatt ttggtcaaag atggtggtgc caaactttgg cttgtgttgt cagctattta
      661 catgtttgta ttcttaacaa acgagcacat tgcggcgaac tttgcttctt tcgcgattgt
      721 gaaattcagt gttgctgcgg attcaattgc caacttcggt gttggaaata tgcttcgcca
      781 ctggggtgtg actttcatcg gaaactttat cggaggaggc ctcttgatgg gtcttccata
      841 tgccttcctc aataaaaacg aagatactta tgtagattaa gaaaatgagc acgattgagt
      901 cgtgcttttt tcattttcaa aataaggtaa tagctatttc ttatatcaaa atatagaaaa
      961 ctgatatttg taaactataa ctcaaggtgc tacaatatcc ttaataaaat aatatggagg
     1021 tcaccttatg actcgtgatt ttaaatttga aactctataa ctacatgctg gtcaagttgt
     1081 ggctccagct actaagtctc gtgcagtgcc gatttatcaa acaacatttt ttgtttttga
     1141 tgacacgtag gaaggtgccg atctgtttgc cttgaggaaa ccagggaaca tttatactcg
     1201 tatcaccaat cctacaacag ctgcccttga aggtggtgtt gaagcgctag caacagcatc
     1261 aggtatgact gcagtgactt atacgatttt ggcgcttgcc catgctggtg agcatgtagt
     1321 ggctgcttcg actatttacg gtggaacctt caatcttttg aaagaacccc ttcctcgtta
     1381 tggtatcaca acaacctttg tcgatgttga taatttggag gaagtagaag cagctatcaa
     1441 agacaatacc aagcttgtct tgattgaaac cttgggtaac cccttgatta atattccaga
     1501 cctggaaaaa ctggcagaga ttgctcataa acatcaaatc ccacttgtgt cagacaatac
     1561 ttttgcaaca ccttatttga ttaacgtctt ctctcatggc gttgacattg ccattcactc
     1621 tgcgactaag tttatcggtg ggcatggtac aactattgga ggaataattg tcgatagtgg
     1681 tcgttttgac tggacggctt cagggaaatt ccctcaattt gttgacgaga gtccaagctg
     1741 ccacaatttg agctatactc atgatgtggg tgcagcagcc tttattatag ctgttcgagt
     1801 tcaattgctt cgtgatacag gtgcagcctt gtcaccattc aatgctttcc tcttgctaca
     1861 aagacttgaa accctttcac ttcgtgtgga acgccatgta caaaatgctg agacaattgt
     1921 tgattttctt gtcaaccatc ttaaggtaga aaaggtaaat tatccaaaac ttgcagatag
     1981 tccttattat gccttggctg agaaatactt gccaaaaggt gtcggttcaa tctttacctt
     2041 ccacgtcaaa ggtgacgagg aagaagcacg caaggtcatt gataatttag aaatcttttc
     2101 tgaccttgca aacgcggcag atgttaaatc gcttgttgtc catccagcaa caatcactca
     2161 cggtcaattg tcagaaaaag acctagaagc agcaggtgtc acaccaaatc aaatccactt
     2221 gtctatcggt cttgaaaatg tagaagattt gattgaagac ttacgcttgg ccttggaaaa
     2281 aatttaaagt aaaagaagat aaacagtggg ttttgactca ctgtttttga ttttccctca
     2341 ggcatgatat aatggttaca gaagtctaga aagaggaatg taatgaacga aatcaaatgt
     2401 cccaactgtg gggaagtctt tacagtaaat gaaagccagt atgctgaact tttgtcccaa
     2461 gtgagaacgg cagagtttga taaggaacta cacgatagga tgaggcagga actggccttg
     2521 gctgagcaaa aggctatgaa tgagcaacag actaaactgg ctcagaagga tcaagaaatt
     2581 gcgcaattgc agagtcaaat ccaaaacttt gatacagaaa aagaattggc caagaaagaa
     2641 gttgaacaga caagccatca ggccttattg gctaaggaca aggaagtaca ggccttggaa
     2701 aaccagttgg cgaccttgcg tttggagcat gaaaatcaat tgcaaaagac cctttctgac
     2761 ctagaaaaag aacgcaatca ggtcaaaaat cagctcctac tgcaagacaa ggaaaatgag
     2821 ttgtctttgg cttctgttaa gcaaaactac gaagcccagc tcaaagcagc cagtgaacaa
     2881 gtcgagtttt ataagaattt caaagctcaa caatccacaa aagccatcgg ggaaagtttg
     2941 gaacactatg cggaaagtga gtttaacaag gttcgtagtt tcgcctttcc aaatgcttac
     3001 tttgagaagg ataacaaggt ctcttcgcgt gggtctaaag gggactttat cttccgtgag
     3061 tgtgatgaaa atggagttga aatcatttct atcatgtttg agatgaaaaa cgaagcggac
     3121 ggaacagaga agaagcacaa gaatgcagat ttttacaagg aattggacaa ggaccgtcgg
     3181 gagaagaact gtgagtatgc cgttttggtg accatgcttg aggctgataa tgactacttt
     3241 aacacaggga ttgttgacgt cagtcacgag tatgaaaaaa tgtatgttgt tcgtcctcaa
     3301 ttctttatcc aattgattgg tctcttacgt aatgcggcgc taaattccct aaaatacaag
     3361 caggagttgg ccttggttcg cgagcaaaat attgacatta cgcattttga ggaagatttg
     3421 gatgccttta agctagcttt tgctaagaac tataattcag cttcgactaa ctttggaaaa
     3481 gctattgatg aaatcgacaa ggccatcaaa cgcatggaag aggttaagaa attcctgact
     3541 acatctgaaa accaactccg tctagctaac aacaaattgg aagatgtctc tgttaaaaaa
     3601 ttgacccgga aaaatccaac aatgaaagcg aagttcgaag cactgaaggg ggagtagaaa
     3661 gcaaaaatga acggtattat caacttaaaa aaagaagcag gaataacctc gcatgatgcg
     3721 gtttttaaac tgcgtaagat tttgggaacc aagaaaattg gtcatggtgg aaccttggat
     3781 ccggatgtgg tgggtgtttt gccgattgcg gttggcaagg cgacacgcat ggtcgagttt
     3841 atgcaggacg agggtaagat ctatgagggg gaaattactc tgggttattc cacgacgact
     3901 gaggatgcta gtggggaagt aatcgcagaa acccctgttt tgtctccctt ggatgaaaag
     3961 cttgttgatg aagcgattgc tagcttgact gggcctatta cccagattcc ccctatgtat
     4021 tcggcagtta aggttaatgg tcgcaagctc tatgagtatg cgcgtgctgg tcaggaagtg
     4081 gagcgtccag aacgtcaggt gaccatttat caatttgagc gaacaagtcc gatttcttat
     4141 gatggccaac ttgctcgatt cacttttcgt gtaaaatgca gtaaagggac ttacatccgt
     4201 actttgtcag ttgatttggg tgaaaagctt ggttatgcgg ctcatatgtc ccatttgact
     4261 cgtactagtg ctgctggctt acaattagaa gatgctcttg ccttggagga aattgctgaa
     4321 aaagtagagg ctgggcaatt agattttctc catcctttag agattgggac aggtgacctt
     4381 gtcaaagttt tcctaactcc agaagaggct acagaagttc gctttggtcg ttttattgag
     4441 ctagaccaaa cggacaaaga actggctgcc tttgaagatg ataaattgtt agccattcta
     4501 gaaaaacggg gcaatctcta taagccaagg aaggttttta gctagatcgt ttaggaataa
     4561 aaatcgggtg atagataata attgcttgat aaaaccccat actaatagta gaatggtttt
     4621 gggaattata atattccaat tgttgcgagt tgtaggtact caaataatct attaggtact
     4681 caaataatct atatagaaat ttagaggtgt gaaatgaagc aatttaaaat tctttcagat
     4741 aaatatttag agtccattac aggttctggt gggaacttag gcccaggatt tggtgtgata
     4801 attccatgat gcgaaatgag tttcgagaaa gggtggagca acttcttcaa caaaaagaaa
     4861 taaatgaaaa tagtgagttg agtcacctgt ttcgtcttgc tatacaaaat ttagacagaa
     4921 atgaaaaata ccaaacggtc atggccaatt tgagtcaagg gttgtcactt tacttcatga
     4981 cgcatcatta ccaggcacct aagtctgtca ttgattttgg tttatggatt gccaaagctc
     5041 ctagccagga aagagggaga ctggctttct tgcagatgct tgctcaaacc ctacagggct
     5101 ttcgttaaaa ctgtcgaaca tcagagggaa gactctggtg ttttttgctg atgagactat
     5161 aaattttgta aaaaatgtga tagaatagac gacggataaa ataacggagg atagcatgca
     5221 aaatagacca atcattattg gagtgacagg tggttctggt ggtggtaaaa ctagtgtttc
     5281 aagagccatt ttatcgcatt ttcctgatga aaagatttcc atgattgagc atgattcata
     5341 ctacaaggat cagtctcatt tgacctttga agagcgtgtc aaaaccaact atgaccatcc
     5401 ttttgccttt gatacagact tgatgatcga gcagattaag gaattgttgg cagggcgtcc
     5461 ggtggacatc ccgacctacg actatacaga gcatacacgg agtagcaaga cctatcgtca
     5521 ggagcctcaa gatgtcttta tcgttgaggg cattttggtc ttggaggaca agcgtctgcg
     5581 cgatttgatg gatatcaaga tttttgtgga tacggatgac gatgtgcgca ttattcgtcg
     5641 tatcaagcgt gatatggagg agcgtggccg tagccttgat agcgttatta accagtactt
     5701 aggtgtggtc aaaccaatgt accaccagtt tatcgagtca actaagcgtt atgctgatat
     5761 cgtcattcct gaaggggtta gcaataccgt ggctatcgac ctgttgacga ccaagattgc
     5821 aaagattttg gaagaagctc gaaacagcaa ataatcacat gtggaggcct tgcctccttt
     5881 ttctattttt ccctcataat ggtacataaa tggagatttt taggcatatt tttggtataa
     5941 taatacccat gaaagagcaa gtaaatgaat agtaggtgga gatggaaaag tatttatcgg
     6001 taacaacttt gaccaagtat ctgaaaatga aattcgataa agacccatac ttggaacggg
     6061 tctatttaac tggtcaagtt tccaactttc gtaaacgacc tactcaccaa tatttctccc
     6121 taaaggatga ccatgcagtt attcaagcga ccatctggtc tgggatttat cagaaattag
     6181 ggtttgacct ggaagaagga atgaagatca atgtgattgg gcgtgtacag gtctatgaac
     6241 caagtggtag ctactccatc atcattgaaa aagctgagcc tgatggggtt ggggcgcttg
     6301 cgattcagtt tgaacaactt aagaaaaaat tgacagaaga aggcctgttt caagaacgct
     6361 tcaagcaagc tctaccccaa ttttctaaga gaattggggt agtaaccagc cgtagtggag
     6421 ccgttattcg agatattatc acgaccgtca gcaggcgatt cccaggtgtt gacatccttc
     6481 tttatcctac caaggttcaa ggtgaagggg ctgcggagga aattgctaga aatattgcgc
     6541 gtgctaatca acgggacgat ttggatttgc tcattattgg tcgtggaggt ggttctattg
     6601 aggatctctg ggcctttaac gaagaaattg tggtacgagc tatttttgaa tctcgtttgc
     6661 cagttatctc tagtgtgggg catgagacgg atgtgacctt ggcagatttt gtggcagatc
     6721 gacgcgctgc aacgccaaca gcggcggctg aactggcaac acctgtgacc aagttggatg
     6781 tattaactca tttgcaaaat caggaaaaac ggatggcaac ggcagtccga aatgttctat
     6841 ctaagaaaca agaggctttg aaaaaatgca gtcagtctgt tatctttaga caacctgagc
     6901 gcttgtatga cggttatttg caacgcttgg accaactgca actgcgtttg aaacaaagtt
     6961 tgcgaactcg gatttctgat aacaaacaat tagttcaagc aagaactcat caattagtac
     7021 aattatcacc tgttaccaaa atccaacgct atcaagaccg tttaggacag ttggacaagc
     7081 tcttaggtag ccaaatggcg ttagtttatg acgccaaggt tgctgaggcc aagcgacttt
     7141 cggaagcttt gctcatgttg gatactagcc gaatcgtggc gcgtggttat gctattgtca
     7201 aaaaagaaga gtccattgta gattcggttg agagtttgaa gaaaaaagac caagtaacgc
     7261 ttttgatgcg agatggtcaa gtagaattag aggttaaaga tgtcaaaaca aaagaaattt
     7321 gaggaaaatc tagcagaact ggaaaccatt gtccaaagtt tggaaaatgg tgaaattgct
     7381 ctggaagatg cgattactgc ctttcaaaag ggcatggtct tgtcaaaaga gctccaagct
     7441 acgctggaca aggctgaaaa gaccttggtc aaggtcatgc aagaagacgg aacagaaagt
     7501 gattttgaat gaaaaagcaa gaaaaattag ctcttgtcga gtcggctttg gaagattttt
     7561 atggagacca gcagtttgcc tctagtttac gggagtctgt tctctattct attcatgctg
     7621 gtggcaagcg tattcggcct tttctcttgt tagaagttct ggaagccttg caggttacca
     7681 tcaaacctgc tcacgcgcag gtagctactg ccttggagat gattcataca gggagcttga
     7741 ttcacgatga ccttcctgct atggatgatg acgattatcg aagagggcgg ttaaccaatc
     7801 acaagaaatt cggtgaagct atggccattt tggctggaga tgccttattc ttagacccat
     7861 atgccttgat tgcgcaggca gatttgccaa gtcagattaa ggtggacttg attgccaact
     7921 tatcccttgc ttcaggtagt ctgggtatgg tggcagggca agttttggat atggagggcg
     7981 aacaccagca cttgtctttg gaagaacttc agattattca tgccaataag actgggaagt
     8041 tactagccta tcccttccaa gcggcagcta ttatagctga attgtcacct gaaatgcagg
     8101 tgaagctgaa aactgtgggt gaattgattg gacttgcttt tcaagtcaga gatgatgtac
     8161 tggatgtgac agctagtttt gaggaaatcg gcaagacacc tcaaaaggat ctgcaggcag
     8221 aaaaatcaac ctatcctgcc ctgttgggct tggaagagtc cattgccttt tgtaaccaaa
     8281 ccctggatca agctaatgaa aaattagaag aaattgccca gcagcttccc tttgaaacag
     8341 aatcgattgt aagtgtagta gaaagtttga gaatcaatgg ctaaggaaag agtggatgta
     8401 ctagcttata aacaggggtt gtttgaaacg agagagcagg ccaagcgagg tgtaatggct
     8461 ggcctagtcg tagcagtcct taatggagaa cggtttgaca agccaggaga gaaaattcca
     8521 gatgacaccg aattaaaact caagggagag aaactcaagt atgtcagccg tggtggtttg
     8581 aaactggaaa aggccttgca ggtctttgat ttgtcggtgg atggcgcgac tacgattgat
     8641 atcggggcct ctactggagg ttttaccgat gtcatgctac agaatagtgc caagttggtc
     8701 tttgcagtcg atgttggtac caatcagttg gcttggaaat tacgccaaga cccacgagtt
     8761 gttagcatgg agcagttcaa tttccgctat gctgaaaaga ctgatttcga gcaggagccg
     8821 agctttgcca gtattgatgt gagtttcatt tcccttagtc tgattttgcc agccttgcat
     8881 cgtgtcttgg ctgatcaagg tcaggtggta gcacttgtca aacctcagtt tgaggcagga
     8941 cgtgagcaga ttgggaaaaa tggaattatt cgagatgcta agattcatca gaatgtcctt
     9001 gaatctgtaa cagctatggc agtagaggca ggtttttcag tccttggctt ggacttttct
     9061 cccatccaag gtggacatgg aaatattgaa tttttagcgt atttgaaaaa agaaaagtca
     9121 gcaagcaatc agatttttgc tgagattaaa gaagcagtag agagggcgca tagtcaattt
     9181 aaaaatgaat aaaaaagaga gacttgaaaa aattagaaga ttggtgacag attatcaaat
     9241 cggcacgcaa gaagaaattg tagaacattt gaaagaagca ggtatcactg ccactcaggc
     9301 gacggtatcc cgagatatca aagagttagg tattgtcaaa attcctttga gagacaacac
     9361 ctatgtctac gaattaccaa aatcaatcgt aaaaagtctg caactggctg aagacaatat
     9421 cgaatcggct gaattgatgg ataagatgat caatctccaa gttattccag gaaatacggc
     9481 ttttgtaaaa gctcagttaa tcgatacttt tgcagacaag atttttagtt gtttgactga
     9541 taatagctcg attttagtca ttgccagaag tggaagtcta gcagaggaaa tctttgaaca
     9601 agtaaaaaat tggtaggtct atatgttact tgaaatttcg ataaaaaact ttgccattat
     9661 tgaggctatt tccctcaatt ttgaaaaggg gatgactgtc ctgactggtg aaacgggtgc
     9721 agggaagtcg attatcattg atgccatgaa tatgatgttg ggagctcgtg cgacgacaga
     9781 tgttattcgt catggtgcac caaaggcaga gattgagggg cttttctcag ttgagaatag
     9841 tcgtctttta caggaaattt ttgatgagca aggtttagaa ttaggtgatg aaattatcat
     9901 ccgtcgggaa atcttgcaaa atggtcgtag tatcagccgt gtaaatggtc agatggttaa
     9961 tctgtctgtt ttgcgagcta ttgggcaaca tcttgtagat attcatggtc agcatgacca
    10021 tgaggagtta atgcgtcccc aactgcatat ccagatgttg gatgaatttg gtgatgccgc
    10081 tttttgggac ttgaaagaaa cctatcaaac gagttttgat gcctatcgga aaatgcgcaa
    10141 gcaggttctg gaagtcaaga aaaaccaaca ggaacacaag gaacgtatcg aaatgttgga
    10201 atttcaaatg gcagagattg aggcagcaaa cttgcaggct ggagaagact tggctctcaa
    10261 tcaagagcga gataaactcc tcaaccacaa aaatattgcg gatacactga ccaatgccta
    10321 cagtatgttg gacaatgaag atttttcaag tctggccaat gttcgttcag ctatgaatga
    10381 catggaaagt gtcgaagagt atgatcctga ataccgtgaa atttcaagct ctctgtctga
    10441 gacctactat gttttagaag acattagcaa acgtttggaa gctatcattg aggaccttga
    10501 ttttgatggc aatcgcctga tgcaggttga gaatcgtttg gacctccttc atactattac
    10561 tcgtaagtat ggtgggactg ttgatgatgt tttgctttat tttgccaaga ttacggaaga
    10621 atacaatctc ttgacaggca ataatctttc gtctgaggac atggaagcag agcttaagaa
    10681 gttggaagtc aatcttgtca atttggcagg tcaacttgct tctgctcgtc ataatttggc
    10741 tcagcaactc gaagctgaga ttaaacaaga actgcaagat ctttatatgg aaaaagccca
    10801 gtttcaggtt cattttagta agggaaaatt cagtcgtggg ggaaatgaaa tggttgagtt
    10861 ttatatttca accaaccctg gagaagactt taaacccttg gttaaggttg cttctggagg
    10921 ggaattatct cgtctcatgt tagccattaa gtctgccttt tcacgtaaag aaggcaagac
    10981 tagcattgtc tttgatgagg tggatacggg agtttcaggt cgtgttgctc aagctattgc
    11041 tcagaaaatt cataaaattg gtcagcatgg tcaggttttg gctatctccc atttgccaca
    11101 agtaattgcg attgcagatt atcaattctt tattgagaag attagtaatg accattcaac
    11161 ggtttcgact gttcgtctct tgacagtcga agagcgagtg gaggaagttg ccaagatgtt
    11221 ggcaggtgat gatgtgacag aagcagccct gacgcaagcc agagaattgt tgagaaacag
    11281 ggagaaataa gatgacagat tattatgtaa ttggagatgt tcacggaaaa gctgggatgc
    11341 tggaagacct tcttaaaacc tgggatggtc agacccagtt gctctttcta ggtgatttga
    11401 ttgacagagg tgaggatagt caccgtgttc ttgaaatggt caaggacttg gtggacaatc
    11461 aaggggctat ctgtttgtct ggaaaccacg agtatatgtt tttgacttgg ctagatgacc
    11521 cagaagaaag ttatgaccat tatcgtcgca atggtggaga tacaaccatt aactctatcc
    11581 taggtcgtcc cttggatgca ccagttgatg gagtagaaga tgccaagcgg gttgccgctg
    11641 aagcgtcaga cttggtcgaa ttcattcgtc aaatgccatt tgtagtagag acagacaagt
    11701 atatatttgt tcacgcaggt attgatttga ctttggacga ctggcatgaa acaacagatt
    11761 ataaaaaagt atggcttaga aaaccattcc acggagctga aaatcatact ggaaaaacca
    11821 ttgtcttcgg tcatacaccg gtctatggtt tgttacagca agaacgcggt acatctgagc
    11881 tttggactac agaagatggc aagattggaa tggatggagg agctgtttat ggtggtgtcc
    11941 ttcacgggat tgtctttaca gaccaaggaa tgacagaaca ccactttatc gaaaatgacg
    12001 gctttgtcgc tgaagattag tactcctagc agggtatggt cttgtcaaaa tatcaaaaac
    12061 aatttataat aaatagatac cctgaaagga agagaatcat gaacttagaa gaattgaaaa
    12121 aacgacaggg gaagatccgt aacttctcta ttatcgccca tattgaccac gggaaatcaa
    12181 ctctagcaga ccgcattttg gaaaaaacag agacggtttc aagtcgtgaa atgcaggccc
    12241 agcttttgga tagcatggat ctagagcggg aacgtggaat tactattaag ttgaatgcca
    12301 tcgagttgaa ttacactgca aaagatgggg aaacttatat tttccacttg attgacacac
    12361 cagggcacgt tgactttacc tatgaagttt cacgttcgct agctgcctgt gagggtgcta
    12421 ttttggtggt cgatgcggct caaggaattg aggctcaaac tcttgccaac gtttatctgg
    12481 ctttggataa tgatttggaa atcatgccta tcattaataa aattgacctg ccggctgcag
    12541 atccggagag cgtgcgtaca gagattgaag atgtgattgg tttggatgcc agtgaagcag
    12601 ttttggcttc tgccaaggct ggtattggga ttgaagaaat cctcgagcaa attgtagaaa
    12661 aagtaccagc accaacgggt gatgtgacgg cgccacttaa ggccttgatt ttcgactctg
    12721 tttacgatgc ttaccgtggg gttatcctcc aagtgcgtgt catggacgga gtggtcaaac
    12781 ctggtgataa gattcagctc atgagcaata gtaagacctt tgatgtggcc gaagtcggta
    12841 tttttacacc aaaagcggtt ggtcgtgatt tccttgcgac tggtgatgtt ggttacattg
    12901 cggcgtctat caagacggtt caggatactc gtgtgggtga taccgttacc ttggcaacca
    12961 atcctgcggc agaaccatta catggttata agcagatgaa tcctatggtc tttgcgggtc
    13021 tctacccaat cgaatcaaac aagtacaatg acctgcgtga agcgcttgaa aaattgcaac
    13081 tgaatgatgc tagtcttcag tttgaaccag aaacatctca ggcacttgga tttggtttcc
    13141 gttgtggatt tcttggactt ctccatatgg atgttatcca ggaacgttta gagcgtgagt
    13201 tcaatattga tctcatcatg acagctccgt ctgttattta caaagttaat ttgaccgacg
    13261 gtgagtctat ggatgtgtct aacccatctg agtttccaga cccaactaag attgcgacca
    13321 ttgaagagcc ttatgtcaag gcgcaaatca tggtaccaca ggagttcgtc ggagcagtaa
    13381 tggagctagc tcagcgtaag cgtggggact ttgtgactat ggactatatt gatgataacc
    13441 gtgtcaatgt tatctatcaa attcctcttg ctgaaatcgt ctttgacttc tttgataaac
    13501 ttaagtcttc gacacgtggt tatgcaagtt ttgactacga attgtcagaa tatcgcccat
    13561 ctaagctagt gaaaatggat atccttctca acggagacaa ggtggatgcc ctcagcttta
    13621 tcgttcataa ggactttgct tatgaacgtg ggaaactcat cgttgataag ctcaagaaaa
    13681 tcatccctcg ccaacaattt gaggttccaa tccaagcggc tattggacac aagattgtcg
    13741 ctcgtactga tatcaaggcc cttcgtaaga acgtacttgc taaatgttat ggtggtgacg
    13801 tttctcgtaa gcgtaaactc cttgaaaaac aaaaagctgg taagaaacgc atgaaatcca
    13861 tcggatcagt tgaagttccg caagaagcct tcctcagcgt cttgagtatg gatgaagaat
    13921 aagttatcag aaatgccttt ccttgttcac aggaaattta tataagaatc aatagtaaag
    13981 caggcttaga tggtctgctt ttttagtttt tatactcttc gaaaatctct tcaaaccacg
    14041 tcagcgtcgc cttaccgtat gtatggttac tgacttcgtc agtttcatct acaatctcaa
    14101 aaccatgttt tgagctgact tcgtcagttt catctacaac ctcaaaacca tgttttgagc
    14161 tgacttcgtc agtttcatct acaacctcaa aactgtgttt tgagtaacct gcggctagct
    14221 tcctagtttg ctctttgatt ttcattgagt attagaacag aaaaatgctt ggagtatttg
    14281 tttgtgtgtt tatttttata taacaaacta taaacacaac aaaaatataa aaaaagagac
    14341 aaaaaagaac agaaagtaat taacaacgat ttcatatagt gttatactta tagcataaag
    14401 ttaatggaaa gaagggaaaa ccttatggta ttagattatt tctttgacaa aaaccttgtg
    14461 ttttgcttag aagcggataa tcaagaataa ctctttgatc aggtagcaag cttgttggag
    14521 gaacgagaaa ttgtaactcc aacttatcgt gaagctttga tcacgcgtga aaagtcattt
    14581 ccaactggtt tagatatgga atttctagga aaggacttgc aaatgtaatg attcctcaca
    14641 cagatattgt tcataatcta gctgagaaag tggtggttgt tcgattagag aaaccggtga
    14701 ctttccataa tatgattgcg ccaggtaagg aagtagaagt atccttgctc ttctttatca
    14761 tcaataattc aagttcaagt caaacgaaca ttcttgctca gttgatggac tttttcacag
    14821 gaaatggaca tcttgaagac ctatcaaaaa tttccgaacc agaaaaactt tatgcttata
    14881 tagatgaagc aatcgcttaa tcttgtctat taaaaaataa aatcggagga agtctatatg
    14941 attaaaattc ttgctgcctg cggtgcaggt gttaactcaa gtcaccaaat taaaagtgct
    15001 ctagaagaag aactttcaaa ccgtggttac gatgttcact gtgatgcagt
//
LOCUS       DBEJHE010000039        14691 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC4 isolate 671759
            SAMN38261586-rid24793303.denovo.39, whole genome shotgun sequence.
ACCESSION   DBEJHE010000039 DBEJHE010000000
VERSION     DBEJHE010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261586
            Sequence Read Archive: SRR26833752
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 14691)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14691)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576136.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576136.1
            Genome Coverage       :: 109x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 19:48:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,067
            CDSs (total)                      :: 2,029
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 131
            CDSs (without protein)            :: 131
            Pseudo Genes (ambiguous residues) :: 0 of 131
            Pseudo Genes (frameshifted)       :: 64 of 131
            Pseudo Genes (incomplete)         :: 59 of 131
            Pseudo Genes (internal stop)      :: 46 of 131
            Pseudo Genes (multiple problems)  :: 32 of 131
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14691
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261586-rid24793303.denovo.39"
                     /strain="GPSC4"
                     /isolate="671759"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            35..491
                     /locus_tag="ACL3EZ_001767"
                     /pseudo
     CDS             35..491
                     /locus_tag="ACL3EZ_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811998.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
     gene            656..955
                     /locus_tag="ACL3EZ_001768"
     CDS             656..955
                     /locus_tag="ACL3EZ_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HGR0393297.1"
                     /translation="MKLINTTNSHSQLVKSQLESTDATLVEVYSAGNTDVIFTQAPLH
                     YEILISNKHRAIREPEIETIQEFFLKRKIDKASVDEANIKTLYSEKLIGISIPIK"
     gene            1216..1539
                     /gene="tnpB"
                     /locus_tag="ACL3EZ_001769"
     CDS             1216..1539
                     /gene="tnpB"
                     /locus_tag="ACL3EZ_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="TnpB, as the term is used for proteins encoded by
                     IS66 family insertion elements, is considered an accessory
                     protein, since TnpC, encoded by a neighboring gene, is a
                     DDE family transposase; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HGR0393298.1"
                     /translation="MMIQLSDLGQVHLVCGKTDMIQGIDSLAYLVKTHFELDPFSGQV
                     FLFCGGRKDRFKALYWDGQGFWILYKRFENGKLTWPSTEKDVKALAPEQVDWLMKGFS
                     ITPQI"
     gene            complement(2268..3995)
                     /gene="ezrA"
                     /locus_tag="ACL3EZ_001770"
     CDS             complement(2268..3995)
                     /gene="ezrA"
                     /locus_tag="ACL3EZ_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HGR0393299.1"
                     /translation="MSNGQLIYLMVAIAVILVLAYVVAIFLRKRNEGRLEALEERKEE
                     LYNLPVNDEVEAVKNMHLIGQSQVAFREWNQKWVDLSLNSFADIENNLFEAEGYNHSF
                     RFLKASHQIDQIESQITLIDEDIAAIRNALADLEKQESKNSGRVLHALDLFEELQHRV
                     AENSEQYGQALDEIEKQLENIQSEFSQFVTLNSSGDPVEAAVILDNTENHILALSHIV
                     DRVPALVTTLSTELPDQLQDLESGYRKLIDANYHFVETDIEARFHLLYEAFKKNQENI
                     RQLELDNAEYENGQAQEEINALYDIFTREIAAQKVVENLLATLPTYLQHMKENNTLLG
                     EDIARLNKTYLLPETAASHVRRIQTELESFEAAIVEVTSNQEEPTQAYSVLEENLEDL
                     QTQLKDIEDEQISVSERLTQIEKDDINARQKANVYVNRLHTIKRYMEKRNLPGIPQTF
                     LKLFFTASNNTEDLMVELEQKMINIESVTRVLEIATNDMEALETETYNIVQYATLTEQ
                     LLQYSNRYRSFDERIQEAFNEALDIFEKEFDYHASFDKISQALEVAEPGVTNRFVTSY
                     EKTRETIRF"
     gene            complement(4077..6023)
                     /gene="gyrB"
                     /locus_tag="ACL3EZ_001771"
     CDS             complement(4077..6023)
                     /gene="gyrB"
                     /locus_tag="ACL3EZ_001771"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HGR0393300.1"
                     /translation="MTEEIKNLQAQDYDASQIQVLEGLEAVRMRPGMYIGSTSKEGLH
                     HLVWEIVDNSIDEALAGFASHIQVFIEPDDSITVVDDGRGIPVDIQEKTGRPAVETVF
                     TVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVHVHKNGKIHYQEYRRGHVVAD
                     LEVVGDTDRTGTTVHFTPDPEIFTETTIFDFDKLNKRIQELAFLNRGLQISITDKRQG
                     LEQTKHYHYEGGIASYVEYINENKDVIFDTPIYTDGEMDDITVEVAMQYTTGYHENVM
                     SFANNIHTHEGGTHEQGFRTALTRVINDYARKNKLLKDNEDNLTGEDVREGLTAVISV
                     KHPNPQFEGQTKTKLGNSEVVKITNRLFSEAFSDFLMENPQIAKRIVEKGILAAKARV
                     AAKRAREVTRKKSGLEISNLPGKLADCSSNNPAETELFIVEGDSAGGSAKSGRNREFQ
                     AILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGAEFDVSKARYQKLVLMTDAD
                     VDGAHIRTLLLTLIYRYMKPILEAGYVYIAQPPIYGVKVGSEIKEYIQPGADQEIKLQ
                     EALARYSEGRTKPTIQRYKGLGEMDDHQLWETTMDPEHRLMARVSVDDAAEADKIFDM
                     LMGDRVEPRREFIEENAVYSTLDV"
     gene            complement(6038..6601)
                     /locus_tag="ACL3EZ_001772"
     CDS             complement(6038..6601)
                     /locus_tag="ACL3EZ_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HGR0393301.1"
                     /translation="MKYHDYIWDLGGTLLDNYETSTAAFVETLALYGITQDHDSVYQA
                     LKVSTPFAIETFAPNLENFLEKYKENEARELEHPILFEGVSDLLEDILNQGGRHFLVS
                     HRNDQVLEILEKTSIAAYFTEVVTSSSGFKRKPNPESMLYLREKYQISSGLVIGDRPI
                     DIEAGQAAGLDTHLFTSIVNLRQVLDI"
     gene            complement(6686..7240)
                     /locus_tag="ACL3EZ_001773"
     CDS             complement(6686..7240)
                     /locus_tag="ACL3EZ_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1 family glyoxalase III"
                     /protein_id="HGR0393302.1"
                     /translation="MVKVAVMLAQGFEEIEALTVVDVLRRANITCDMVGFEEQVTGSH
                     AIQVRADHVFDGDLSDYDMIVLPGGMPGSAHLRDNQTLIQELQSFEQEGKKLAAICAA
                     PIALNQAEILKNKRYTCYDGVQEQILDGHYVKETVVVDGQLTTSRGPSTALAFAYELV
                     EQLGGDAESLRTGMLYRDVFGKNQ"
     gene            complement(7251..8474)
                     /locus_tag="ACL3EZ_001774"
     CDS             complement(7251..8474)
                     /locus_tag="ACL3EZ_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HGR0393303.1"
                     /translation="MKRSLDSRVDYSLLLPVFFLLVIGVVAIYIAVSHDYPNNILPIL
                     GQQVAWIALGLVIGFVVMLFNTEFLWKVTPFLYILGLGLMILPIVFYNPSLVASTGAK
                     NWVSINGITLFQPSEFMKISYILMLARVIVQFTKKHKEWRRTVPLDFLLIFWMILFTI
                     PVLVLLALQSDLGTALVFVAIFSGIVLLSGVSWKIIIPVFVTAVTGVAGFLAIFISKD
                     GRAFLHQIGMPTYQINRILAWLNPFEFAQTTTYQQAQGQIAIGSGGLFGQGFNASNLL
                     IPVRESDMIFTVIAEDFGFIGSVLVIALYLMLIYRMLKITLKSNNQFYTYISTGLIMM
                     LLFHIFENIGAVTGLLPLTGIPLPFISQGGSAIISNLIGVGLLLSMSYQTNLAEEKSG
                     KVPFKRKKVVLKQIK"
     gene            complement(8511..10961)
                     /locus_tag="ACL3EZ_001775"
     CDS             complement(8511..10961)
                     /locus_tag="ACL3EZ_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DnaQ family
                     exonuclease/ATP-dependent helicase"
                     /protein_id="HGR0393304.1"
                     /translation="MKTIGNRYVVVDLEATSTGSKAKIIQVGIVVIEDGEIVDHYTTD
                     VNPHEPLDAHIKELTGLTDQRLAQAPDFSQVARKIFDLVEDGIFVAHNVQFDANLLAE
                     NLFFEGYELRNPRVDTVELAQVFFPELEKYSLPILCRELGIPLKHAHTALSDAQATAE
                     LLLFLRKKMTQLPKGLLERLLEMADALLYESYLVIEETYRNQSILSSPDLVQVQGLYF
                     KKTEASLEPRKLSQDFSKNISLLNLEVREEQESFAKEVGLLLKDEPVSLIQAPTGIGK
                     TYGYLLPALSQSKERQIVLSVPTKILQNQIMEEEGKRLKEVFHTDIHSLKGPQNYLKL
                     DAFYHSLQENDENRLFRRFKMQVLVWLTETETGDLDEIGQLYRYQHFLADLRHDGNLS
                     SQSLFVTEDFWKRSQERAETCKLLVTNHAYLVTRLEDNPEFVSDRLLIIDEVQKILLA
                     LENLLQETYDIQSIIDLIDKALVGEENRVQQRILESIRFECLYLIEQFQSGKSRKNIL
                     DSLDNLHQYFSELEVEDFDELVRYFTAEGDYWLEVTETSQKKIQISSTKSGRTLLSSL
                     LPESCQVLGVSATLEISQRVSLADLLGYPEAKFVKIESRGKQEQEVVMVKDFPLVTET
                     SLEVYAREVAALLVEIQAFQQPILVLFTAKDMLLAVSDLLTVGHLAQYKNGDVHQLKK
                     RFEKGEQQILLGAASFWEGVDFSSHPFVIQVVPRLPFQNPQEPLTKKINQELSQEGKN
                     AFYDYQLPMAIIRLKQALGRSMRREYQRSLTLILDRRIIGKRYGKQIVASLAEEATVK
                     TISRSEVDEAIDRFFNEL"
     gene            complement(11161..12090)
                     /locus_tag="ACL3EZ_001776"
     CDS             complement(11161..12090)
                     /locus_tag="ACL3EZ_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006154193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase U32 family protein"
                     /protein_id="HGR0393305.1"
                     /translation="MEKIVITATAESIEQVEQLLEAGVDRIYVGEKDFGLRLPTTFSY
                     DQLREIAKLVHDAGKELIVAVNALMHQDMMDRIKPFLDFLEEIKTDYITIGDAGVFYV
                     VNRDGYSFKTIYDASTMVTSSRQINFWGQKAGASEAVLAREIPSAELFKMPEILEIPA
                     EVLVYGASVIHHSKRPLLQNYYNFTHIDDEKTHKRDLFLAEPSDPESHYSIFEDNHGT
                     HIFANNDLDLMIKLTELVEHGFTRWKLEGLYTPGQNFVEIAKLFIQARSLIQEGNFSH
                     AQAFLLDEEVRKLHPKNRFLDTGFYDYDPDMVR"
     gene            12230..12517
                     /locus_tag="ACL3EZ_001777"
     CDS             12230..12517
                     /locus_tag="ACL3EZ_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3270 domain-containing protein"
                     /protein_id="HGR0393306.1"
                     /translation="MPVRKLQSYEVDYQEELNQQLPHYQAYTPEAQSDANLKEILFFI
                     NIAVFCICIAIFSFIFLALKLSTALAFAAAIGFSLLVLKVQRSIIKRKRRR"
     gene            complement(12551..13885)
                     /gene="ciaH"
                     /locus_tag="ACL3EZ_001778"
     CDS             complement(12551..13885)
                     /gene="ciaH"
                     /locus_tag="ACL3EZ_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000491790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     CiaH"
                     /protein_id="HGR0393307.1"
                     /translation="MFSKLKKTWYADDFSYFIRNFGVFTLIFSTMTLIILQVMHSSLY
                     TSVDDKLHGLSENPQAVIQLAINRATEEIKDLENARADASKVEIKPNVSSNTEVILFD
                     KDFTQLLSGNRFLGLDKIKLEKKELGHIYQIQVFNSYGQEEIYRVILMETNISSVSTN
                     IKYAAVLINTSQLEQASQKHEQLIVVVMASFWILSLLASLYLARVSVRPLLESMQKQQ
                     SFVENASHELRTPLAVLQNRLETLFRKPEATIMDVSESIASSLEEVRNMRFLTTSLLN
                     LARRDDGIKPELAEVPTSFFNTTFTNYEMIASENNRVFRFENRIHRTIVTDQLLLKQL
                     MTILFDNAVKYTEEDGEIDFLISATDRNLYLLVSDNGIGISTEDKKKIFDRFYRVDKA
                     RTRQKGGFGLGLSLAKQIVDALKGTVTVKDNKPKGTIFEVKIAIQTPSKKKK"
     gene            complement(13875..14549)
                     /gene="ciaR"
                     /locus_tag="ACL3EZ_001779"
     CDS             complement(13875..14549)
                     /gene="ciaR"
                     /locus_tag="ACL3EZ_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CiaR"
                     /protein_id="HGR0393308.1"
                     /translation="MIKILLVEDDLGLSNSVFDFLDDFADVMQVFDGEEGLYEAESGV
                     YDLILLDLMLPEKNGFQVLKELREKGITTPVLIMTAKESLDDKGHGFELGADDYLTKP
                     FYLEELKMRIQALLKRSGKFNENTLTYGNIVVNLSTNTVKVEDTPVELLGKEFDLLVY
                     FLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKVRKKLKGTTFAENLQTLRSVGY
                     LLKDVQ"
BASE COUNT         4519 a         3089 c         2611 g         4472 t
ORIGIN      
        1 actataataa taacgatact agataatgag gaaaatgcaa tggcaaaccc aactttcgga
       61 gaaaaaaagc gaatacagac tatattgctc gctatggcgt atatgcagtt atccctaatc
      121 ctgaacaaaa acaaattgtt cttgttcaag aaccaaatgg tgcttggttc ctaccatgtg
      181 gagaaattga agcaggtgaa aatcatcagg aagccctaaa gcgtgagttg attgaagagc
      241 ttggtttcac agcagaaatt ggtacctatt acggacaagc tgacgaatat ttctattctc
      301 gtcatcgtga tacctactac tacaatcctg cctacctcta tgaagcaact cctttcaaag
      361 aagtacaaaa gccactagaa aactttaatc atattgcctg gttccctatt gacgaggcta
      421 tcaaaaacct taaacgtggt agccataaat gggccattga atcttggaaa aaacagcata
      481 agattgacta atactcttcg aaaataaaat tcaaaccaca tcagcgtcgc cttaccatac
      541 tcaagtatag cctgcggcta gcttcctagt ttgctctttt attttcattg agtataaatc
      601 aagcgacttt attcaaaaag tgctataata gaattagaaa atcggaggaa atattatgaa
      661 gcttatcaat acgacaaact cacactcgca acttgtaaaa agtcagctag aaagtaccga
      721 tgcaaccctt gttgaggttt attctgcagg gaatacagat gttattttta cccaagctcc
      781 gcttcactat gaaatcctca tctcaaacaa acaccgtgct attcgtgagc ctgaaatcga
      841 aaccattcaa gaatttttct tgaaacgtaa aattgataag gcctctgttg atgaagccaa
      901 tatcaagaca ctctactcag agaaattaat tggaatttca atcccaatca agtaagaaaa
      961 ttgagtaaaa actcgatttg agagaaagtc caataagtct ttccataata aaacgcatag
     1021 tagcaagagt ttctacaccc actattatac gtttttatca ttttgaaatc tgctgctaat
     1081 caatgaagaa gcaaagatca aactaggcag ctagttacaa gttacgtaag cgcgtcataa
     1141 caaggtatct atcctaattc cccaacttcc agtatactag ataaaaaata attatcggag
     1201 gaaaagtatt gtactatgat gattcaacta agtgatttag gtcaagttca ccttgtttgt
     1261 ggcaagacag atatgataca aggaatcgat tcactggctt atctcgttaa aacccacttt
     1321 gaattggatc ctttctccgg tcaagtcttt ctcttttgtg gtggacgtaa agaccgcttt
     1381 aaagcccttt actgggatgg tcaaggattt tggatactat ataaacgctt tgagaacgga
     1441 aaactgactt ggcccagtac agaaaaggat gtcaaagctc tcgcacctga acaagtagac
     1501 tggcttatga agggcttttc tatcactccc caaatatagt ggatttaaac tagaatagta
     1561 cacccctact tctaaaacat tgttagaaat cgatttgact gtcctgatca atttgtcctg
     1621 ttcttgtttc attttactat agaacgattt gaaggcgttt atgatattta gctgtacgag
     1681 agtcttttaa aagtgttttg atggtttgga tttcttcttt agttgatttt atattactat
     1741 tatataatga ttttttattt tagtctagta taaatagcga gaaatatcta tcctatcttc
     1801 tagaatgtct tccaaacgag aaaactctcg taaacaaaga ggttttagag gcctatttac
     1861 cgtggactaa agttgtacaa gaaaagtgca aataagaaat ctccagatta ggaactatcc
     1921 gtgagttctc tagtctggag atttttcaat agacttcgtt attggacggt taccaagtta
     1981 ctcaaagtac agatttgaag ctgcagataa gactgacgaa atcactttaa tactaaatga
     2041 aaatcaaaaa gcaaactaag aagctagcct caggctgtac ttgagtacgg taaggcgacg
     2101 ctgacgtgat ttgaagagat tttcgaagag tataaaacac tgttttgagg tggtggataa
     2161 atcggctggg taaaaactca atctcaggag aaaatgaagt aaatctcccc acaactatag
     2221 aaaaagattt gattctgctc ctcacacaat aaaatctttt tcttttatta aaaacgaatc
     2281 gtttcacgtg ttttctcata tgaggtaaca aagcgattgg ttacaccagg ctctgccact
     2341 tccaatgctt gagaaatctt gtcaaatgaa gcgtgataat caaattcttt ttcaaaaata
     2401 tctaaagctt cgttaaatgc ttcttgaatg cgttcatcaa atgagcgata gcggttagaa
     2461 tattgcaaga gttgctctgt caaagttgca tattgtacaa tattataagt ttccgtttct
     2521 aaagcttcca tatcattcgt tgcaatttca agaactcggg taacagattc aatgttaatc
     2581 attttttgtt ctaactcaac cattaaatcc tcggtattat tgcttgccgt aaagaataac
     2641 ttcaagaaag tttgtggaat acctggcaga ttgcgttttt ccatgtatcg cttgatagta
     2701 tggagacgat tgacataaac attggccttt tgacgtgcat taatatcatc tttctcaatt
     2761 tgtgtcaggc gctcactaac tgaaatttgc tcatcttcaa tatcttttag ttgagtttgt
     2821 aaatcctcaa gattttcttc aagaactgaa taagcttggg ttggttcttc ttgatttgaa
     2881 gttacctcaa caatagctgc ctcaaaactc tctaattctg tctgaatacg acgaacatgg
     2941 cttgcagctg tctcaggaag taaataggtc ttgttcaaac gtgcaatatc ttctcccaat
     3001 aaagtattat tctctttcat atgttgaagg taagttggaa gagttgcaag tagattttcc
     3061 actactttct gagcagcaat ttctcgagta aaaatatcat acaaggcatt gatttcctct
     3121 tgtgcctgtc cattctcata ttcggcatta tccaattcca actgacgaat attctcttgg
     3181 tttttcttga atgcttcata aagcaagtgg aaacgcgctt caatatccgt ttcaacaaaa
     3241 tgataattag catcaattag tttacgataa ccggattcca aatcctgtaa ttgatctggc
     3301 aattctgtag aaagcgtcgt aaccaaggct ggaacacgat ccacaatatg acttaaggcc
     3361 aaaatgtgat tttctgtatt atccaaaatc actgcggctt ccacagggtc acccgatgaa
     3421 ttcaaggtta caaattgtga aaattcagat tggatatttt ctaattgttt ttcaatttca
     3481 tccaaggctt gaccatactg ttctgaattt tcagcaactc tatgctgaag ttcctcaaat
     3541 aaatccaaag catgaagaac acgaccacta tttttagatt cttgcttctc taagtctgcc
     3601 aaagcattgc gaattgccgc aatatcttcg tcaatcaaag taatttgact ctcaatttgg
     3661 tcaatttgat gactggcctt gagaaaacga aatgaatggt tatagccttc tgcttcaaag
     3721 agattatttt caatatcggc aaaagagttg agagataaat cgacccattt ttgattccat
     3781 tcacggaaag ccacttgact ttgtccaatc aagtgcatat tttttacagc ttctacttca
     3841 tcatttactg gaagattgta tagttcttct tttctttctt ctagcgcctc taatctcccc
     3901 tcgtttcgct tacgtagaaa gattgccact acataagcca gaactaaaat gactgcaatt
     3961 gcaaccatta aataaattag ttgtccatta gacatatcaa actccttttt tacttgaaac
     4021 aatcgtaacg attatatcat attttttaga ccaagggaac tacttctccc tattttttag
     4081 acatcaagtg tactatagac agcattttct tcgataaact cacgacgagg ctctactcga
     4141 tcccccatca acatatcaaa gattttatct gcttctgcag catcatctac agaaactcta
     4201 gccatcaagc gatgttcggg atccatggtt gtttcccaca gctgatgatc gtccatttca
     4261 cctagcccct tataacgctg aatagtcggt ttggtacgac cttcactata acgggctaaa
     4321 gcttcttgga gtttgatttc ttgatctgca cccggctgga tatattcttt aatctcgctt
     4381 ccaaccttga caccatagat tggtggttgg gcaatataaa cataaccagc ttctaggatt
     4441 ggtttcatat aacgataaat caaggttaaa agaagggtac gaatgtgggc tccatcgaca
     4501 tcggcatcgg tcatcaaaac gagtttttgg taacgggctt tcgaaacatc aaattctgcg
     4561 ccaaatcctg ttcccatggc tgtgaaaaga ctacgaattt cttcgttagc tagaatctta
     4621 tccatacttg ctttttcaac gttcaaaatc ttaccgcgaa ttggaaggat agcctgaaac
     4681 tcacggttac gaccagattt ggctgatcca ccagctgagt ctccttcgac gatgaagagt
     4741 tctgtttcag cagggttatt agaagaacag tctgctagtt tccctggaag gttggaaatt
     4801 tccaaaccag attttttacg tgtgacttca cgcgcacgct tggcagccac acgagccttg
     4861 gcagctaaaa tccctttttc cacgatacgt ttggcaatct gtggattttc catgaggaaa
     4921 tcggagaagg cttcactgaa gaggcgattg gtaatcttga ccacttcgct atttcccaat
     4981 ttggtcttgg tttgtccttc aaactgtgga tttgggtgtt taactgagat aactgcagtt
     5041 aatccttcgc gaacatcttc ccctgttaaa ttatcttcat tgtctttcag taacttattc
     5101 ttacgagcat aatcattgat aacacgagtc agtgccgtac ggaaaccttg ttcatgcgtt
     5161 ccaccttcat gggtatgaat attattggcg aaactcatga cattttcatg gtaacctgtt
     5221 gtgtactgca tggctacctc aactgtgata tcatccatct caccgtctgt atagattggt
     5281 gtatcaaaga ttacatcctt gttctcgttg atatattcaa cgtaactagc aatcccacct
     5341 tcataatgat aatgcttggt ttgttccaaa ccttggcgct tatctgtaat tgaaatttga
     5401 agaccgcgat ttagaaaggc caactcttga atccgtttat ttaatttatc aaaatcaaag
     5461 attgttgttt cagtgaaaat ttctgggtcc ggtgtgaagt gaaccgttgt tccagttcta
     5521 tctgtatccc caaccacctc aaggtctgca acaacatgac cacgacggta ttcttggtaa
     5581 tgaatcttac cgtttttatg gacatgaacg tctaattgag tggaaagggc attaactact
     5641 gacgacccca ccccgtgaag accacctgaa accttgtatc caccaccgcc gaactttcct
     5701 ccagcatgaa ggactgtaaa gacggtctca acagcaggac ggcctgtttt ttcctgaata
     5761 tcgactggga taccacgccc atcatccaca acagtaatcg aatcatctgg ctcaataaaa
     5821 acttgaatat ggctggcaaa tcctgccaag gcctcgtcaa ttgagttatc aacaatttcc
     5881 cagactagat ggtgaagacc ttcttttgag gttgatccaa tgtacatccc tggacgcata
     5941 cgaacagcct ctaagccctc taaaacttga atttgactgg catcataatc ctgtgcctgc
     6001 agatttttga tttcttctgt catcttattc ctttttctta tatgtctaat acttgtctta
     6061 aattcacgat actggtaaac aagtgggtat caagtcctgc agcttgacct gcttcgatat
     6121 caatcggccg atcaccaatg acaagaccag agctaatctg atacttttct cttaaataaa
     6181 gcatggattc gggatttggc tttctcttaa agcctgagct agaagtcacc acttctgtaa
     6241 aataagctgc tatagaggtt ttttctaaaa tttccaaaac ctgatcattt cgatgagaga
     6301 ccaaaaaatg acggccacct tgatttaaaa tgtcttccaa taggtcagaa actccttcaa
     6361 ataaaatcgg gtgttcaagc tctctggctt cattttcctt gtacttttct aaaaaattct
     6421 ctaaattggg agcgaatgtc tcaatcgcaa aaggagtaga aacctttaaa gcttgataga
     6481 cactgtcatg gtcttgtgtg ataccataca gtgccaatgt ttcaacaaat gcagctgttg
     6541 aagtttcata attatccagt aaagttccac ctaaatccca gatgtaatcg tgatatttca
     6601 tacccttcat tatagcattt ttttatgaaa aaagcgatga tttccctgag ttttccacat
     6661 aaaaaacgag agaataactc ccgttttact gatttttacc aaagacatct cgatagagca
     6721 ttcctgttcg taaactctct gcgtcccctc ctagttgctc caccaactcg taggcaaagg
     6781 caagggctgt tgaaggaccc cgactggttg tcaactgacc atctaccact actgtttcct
     6841 tgacgtagtg accatcaagg atttgctctt gaacgccgtc ataacaagtg tatcgcttat
     6901 ttttcaatat ctctgcttga ttgagggcaa ttggtgccgc acaaatggct gctagtttct
     6961 tcccttcttg ctcgaagctt tgcaattctt gaatcaaggt ctgattatca cgtaaatgtg
     7021 cagaaccagg catacctcca ggaagaacaa tcatatcata gtctgataaa tctccatcaa
     7081 agacatgatc tgctcttact tggattgcat gcgaacccgt tacttgctct tcaaaaccaa
     7141 ccatatcaca tgtgatattg gctcgacgca agacatctac aactgtcaag gcttcaattt
     7201 cttcaaagcc ctgagctaac ataactgcta cttttaccat gattttctcc ttatttaatt
     7261 tgttttaata caaccttttt ccgtttgaat gggacttttc cgctcttttc ttcagctaaa
     7321 ttagtctggt aactcatcga taaaagcaaa ccaacaccaa tcaaattact gataatagct
     7381 gatccccctt gcgaaatgaa aggcaaggga atccccgtca aaggaagtag tccagtcaca
     7441 gcaccgatat tctcaaagat gtggaagagc aacatcataa tcaaacctgt ggaaatataa
     7501 gtgtagaact ggttatttga tttaagagta atcttcaaca tacggtaaat caacatgaga
     7561 tagagggcaa taaccaggac agagccaata aagccaaaat cttctgcaat aaccgtaaaa
     7621 atcatatctg actctcgaac tgggataagc agattcgaag cattaaatcc ctgaccaaat
     7681 aagccaccac tcccaatggc aatctgccct tgagcctgct ggtaagtcgt tgtttgggca
     7741 aactcaaagg gattgagcca agccaaaatc cgattaattt ggtaagtcgg cattccaatc
     7801 tggtgaagaa aagctcgtcc gtccttgcta ataaagatag ctaagaaacc agcaactcct
     7861 gttacagcag tcacaaatac tgggataata attttccaag aaacccctga taataaaacg
     7921 attcctgaga aaatggctac aaaaaccaaa gccgtcccca agtcactttg aagtgctaaa
     7981 agaactagga ctggaatggt aaagagaatc atccagaaaa ttaacaaaaa gtccagcgga
     8041 accgtgcgtc tccattcctt atgtttcttt gtaaattgga caatgacacg agccaacatg
     8101 aggatatagg atatcttcat aaattctgac ggttgaaata gggtaattcc atttattgat
     8161 acccagtttt tggcacccgt tgatgcaact aagcttggat tataaaatac aatcggcaag
     8221 atcataagtc ccaagcctaa aatatataga aagggggtca ccttccaaag aaattctgta
     8281 ttaaagagca tgaccacaaa accaatcaca agccccaagg caatccaggc gacctgctgc
     8341 cctaaaatgg gcagaatatt attgggataa tcatgactaa cggctatata gatagccacc
     8401 acaccgatga ccagtagaaa aaatactggc aagagcaaac tataatcgac tctagagtcg
     8461 agagaacgtt tcatatgtac taaccttata ctttcataca atactattta tcaaagttca
     8521 ttaaaaaatc tatcaatagc ctcgtcaact tcggatcgag agatggtttt aacagtcgct
     8581 tcttctgcta gagatgctac tatttgtttg ccgtatcgtt ttccgatgat tctcctatcc
     8641 aaaataagag ttaaggaacg ttggtattca cgtctcatac ttcttcccaa agcctgtttt
     8701 aaacgaataa tggccattgg caattgataa tcataaaagg catttttccc ttcttgactc
     8761 agttcttgat taatcttttt cgtcaagggt tcttgaggat tttggaaagg aagcctcggt
     8821 acaacttgaa tcacaaaagg atggcttgaa aaatcaactc cctcccagaa acttgctgca
     8881 ccaagcaaga tttgttgttc acctttttca aagcgtttct ttagctgatg aacatcccca
     8941 tttttatact gggccaagtg gccaactgta agtaaatccg atactgctag aagcatgtct
     9001 ttagcggtaa agagaaccaa aatcggttgc tggaaagctt gaatttccac tagtaaagca
     9061 gctacctctc tggcatagac ttctaaggag gtttctgtta ccagagggaa atctttgacc
     9121 atgaccactt cttgttcctg ttttccccga gattcaatct tgacaaattt agcttcagga
     9181 tagcctaaaa ggtctgccaa agaaaccctc tgactaatct caagagtagc cgatactccc
     9241 aagacttggc aactctcagg aagtaaagag gacagaagag tacggcctga ttttgtagaa
     9301 gaaatctgaa ttttcttttg actcgtttca gttacttcaa gccagtaatc accttcagct
     9361 gtaaaatagc gaaccagctc atcaaagtct tctacttcca attctgaaaa atactgatgg
     9421 agattgtcca gagaatctaa gatatttttc ctagatttgc cagactgaaa ttgttctatc
     9481 aagtagagac actcaaagcg aatactttct agtatccgtt gttgaaccct gttttcttct
     9541 cctactaaag ccttatcaat taaatcgata atagattgta tatcgtaggt ctcttgaagc
     9601 agattttcta gagctaacaa aatcttttgg acttcatcaa taatcagtaa acggtcactg
     9661 acaaattcag gattatcttc aagtctggtt acgagatagg catgattagt cactaaaagc
     9721 ttgcaagtct ctgccctttc ttgactacgt ttccaaaaat cttccgtcac aaataagctc
     9781 tgggatgata aattcccatc atgacgaagg tctgctagaa aatgttggta acggtagagt
     9841 tgcccgattt catccaaatc tcctgtctct gtctcagtaa gccagaccaa gacttgcatt
     9901 ttaaagcgtc taaataagcg attttcatca ttttcctgca aggaatgata aaaggcatcc
     9961 aacttcagat aattttgtgg tccctttaag ctatgaatat ctgtatggaa cacttccttg
    10021 aggcgtttac cttcttcttc catgatttga ttttgaagaa tctttgtcgg aacactaaga
    10081 acaatttgtc gctctttgga ttgagataaa gcgggtaaga gatagccata ggttttccca
    10141 atccctgtcg gcgcttgaat cagagagaca ggttcatctt tcaatagcaa gccaacctct
    10201 ttagcaaaac tttcttgttc ctccctcact tcaaggttca acagagaaat atttttagaa
    10261 aagtcttgag atagttttcg tggctccaga gaagcttccg ttttcttaaa atatagacct
    10321 tgaacttgga ccaagtctgg agaactcagg atagattggt tgcgataagt ttcctcaata
    10381 accaggtagg actcatatag gagagcgtca gccatttcca gcaagcgttc caagagacct
    10441 ttaggaagct gggtcatctt tttccgtaaa aaaagaagta attctgctgt agcttgggca
    10501 tctgaaaggg ctgtgtgtgc gtgtttaaga ggaattccta attctcgaca caaaatcggc
    10561 aaactatatt tttccagttc agggaaaaag acctgggcca attcgaccgt atcaacacga
    10621 gggtttctta gctcatagcc ttcaaaaaat aaattttccg ccaagagatt agcatcaaac
    10681 tgaacattat gggctacaaa aatcccatcc tccaccaagt caaatatttt tctggcaact
    10741 tgcgaaaaat caggtgcttg cgccagacgt tggtctgtca atcctgtcag ttctttgata
    10801 tgagcatcca agggttcatg tggattgaca tccgtcgtat agtgatcgac gatttctccg
    10861 tcctcaatca cgacaattcc cacttggata attttagcct tactacctgt gctagttgcc
    10921 tctaaatcca ccacaacata gcgattacca atcgttttca ttataaaaaa ttataccaaa
    10981 aaaagggcta tttggcacct gcaaacatag gataattttc aaactcaaga acactacttt
    11041 tcttaaaaat cccatcgaat agagcattct agcctgctga tttttgtaaa atagtgaaga
    11101 aatacgaaaa attgagagaa gaaatgtttg catcttcctt ctctcaacga atcatgtatt
    11161 ttatctaacc atgtcaggat cgtagtcata aaatcctgta tcaaggaaac ggtttttagg
    11221 gtgaagttta cgaacttctt catccagcaa gaaggcttga gcatgactaa agttgccctc
    11281 ttgaatcaag ctacgcgctt ggataaagag ttttgcaatc tcaacaaagt tctgaccagg
    11341 agtgtagagc ccttctagtt tccagcgagt aaagccatgc tccaccaatt ctgttaattt
    11401 gatcatcaaa tcaaggtcat tgttggcaaa gatatgggtc ccatgattat cttcaaaaat
    11461 ggaatagtgg ctctctggat cacttggctc agccaagaag aggtcacgtt tatgcgtctt
    11521 ttcatcatcg atatgtgtaa agttatagta gttttgcaag agtggacgtt tagaatgatg
    11581 gatgacgcta gcaccgtaaa ccaaaacttc agcaggaatt tccaaaatct ctggcatttt
    11641 gaaaagttca gctgatggaa tttcacgcgc caaaacagcc tcagatgcgc cagccttttg
    11701 tccccagaag ttaatctgac gactgctagt taccatggtt gaagcatcgt agatggtctt
    11761 aaatgaataa ccatcgcggt taactacgta aaagacgcct gcatccccaa tcgtaatata
    11821 gtctgtcttg atttcttcca agaagtctaa gaaaggcttg atacggtcca tcatatcttg
    11881 gtgcatgaga gcattgaccg caacgatcaa ttccttacca gcatcatgaa ccaacttagc
    11941 gatttcacgt aattggtcat aactaaaggt cgttggcaga cgaagaccaa aatctttctc
    12001 accgacatag atacggtcta cgccagcttc gagtagttgt tcaacttgtt caatactttc
    12061 agcagttgct gtaatgacaa tcttttccat aagaaaaatt ataccacatt tctccaaaat
    12121 cagccatgct ttgaaaatga aaagggactt tattcttttt gtaacctttc tgtaataatt
    12181 ctctgccgaa aaaatgataa aataggtatg tactgttaag gagagaatca tgcccgtaag
    12241 aaaattacaa tcctatgagg tagactatca agaagaatta aaccagcagc ttcctcatta
    12301 ccaagcttat acacctgaag cgcaatctga tgccaatctc aaggaaatcc tattttttat
    12361 taatatcgct gttttttgta tctgtattgc tatctttagt tttatctttt tagcattaaa
    12421 attatcaact gctcttgcct ttgccgcagc aatcggattc agcttacttg ttttaaaagt
    12481 tcaacggtct attatcaaac gaaaacgtag aagataaatc caaaatatcg ccccaattgg
    12541 agcgatattt ttattttttc tttttagatg gtgtctgaat ggcaatcttc acttcaaaga
    12601 ttgttccctt gggtttatta tctttgacag taacagttcc ttttagagca tctacaattt
    12661 gcttggctag ggataatcct aaaccaaaac cacctttttg ccgggttcta gccttgtcta
    12721 ctcgataaaa acggtcaaaa attttctttt tatcttctgt cgaaataccg attccattat
    12781 cagaaacaag taaataaaga ttgcgatcgg tcgccgagat aagaaaatca atttcaccat
    12841 cctcctcagt atacttgacg gcattatcga aaagaatggt catcagttgt ttcagaagaa
    12901 gctgatctgt gacaattgtt cgatggatac gattttcaaa acggaagaca cgattatttt
    12961 ccgaagcaat catctcatag tttgtgaaag ttgtattaaa aaagctagtt ggaacttctg
    13021 caagctccgg cttaatccca tcatctctcc gagctaagtt cagcaagctt gtcgttaaaa
    13081 aacgcatatt tcggacttct tccaaactcg atgcaatgct ttcgctcaca tccataatgg
    13141 tagcttctgg cttacgaaaa agggtctcta agcgattttg caaaactgcg agtggagttc
    13201 gtaactcatg actggcattt tccacaaaag actgttgctt ctgcatactc tcaagcaggg
    13261 gcctaacact gaccctagct agatagagac tggcaagtaa agacaaaatc cagaaactag
    13321 ccatcacgac cacaatcaat tgctcatgct tttgactagc ctgctccaac tgactggtat
    13381 taatcaagac agcagcatac ttgatattgg ttgaaaccga actaatattg gtctccatca
    13441 aaatcacacg atagatttct tcctgcccat agctattaaa aacctgaatc tggtagatat
    13501 gtcctagttc tttcttttct aacttaatct tatccaagcc caaaaatcga tttccagaaa
    13561 gaagttgagt aaagtcttta tcaaagagaa tgacttccgt attggaactg acattaggtt
    13621 ttatttctac tttactagcg tccgccctag cattttctaa atctttaatc tcttctgttg
    13681 ccctatttat agccagctga ataactgctt gaggattttc actcagtcca tgaagcttat
    13741 cgtccaccga agtataaaga ctcgaatgca tgacttgtaa aataatcaga gtcattgtag
    13801 aaaaaatcag ggtgaagaca ccgaagttgc ggataaaata actaaagtca tccgcatacc
    13861 atgttttttt aagtttactg aacatctttt aaaagatacc caacactacg caaggtttgc
    13921 aaattctctg caaaagtggt tccctttaat ttcttacgga cttttgaaac atagacttcg
    13981 acaaccgaaa tcgttgtatc actatcaaat ccccatagac ggtcaaaaat ctgcgtctta
    14041 ggcaaaatca cattttgatt ttgaaggaaa taaactagta aatcgaactc tttccccagc
    14101 aattcgacag gagtatcttc aactttaacg gtattggttg ataaattaac cacgatattc
    14161 ccataagtca aggtgttttc attaaacttc cctgaacgtt tgagaagggc ctgaattcgc
    14221 attttaagtt cttctaggta gaaaggtttg gtcagataat catccgctcc cagttcaaat
    14281 ccatgtccct tgtcatccaa actttccttg gcagtcataa tcagaactgg tgtcgtaatt
    14341 cccttttcac gcaattcttt taagacttgg aaaccatttt tttctggcaa catcaaatcc
    14401 agcaaaatca agtcatagac accactctca gcttcgtaga gaccttcttc tccatcaaat
    14461 acctgcataa catccgcaaa atcgtctaaa aagtcaaata ctgaatttga cagacctagg
    14521 tcatcctcaa ccaataagat ttttatcatg agaaactcct ccttattaaa actattatac
    14581 caaatttgcc ttaaaaaaaa ctcaactctc tgcattttac atgagatagc tgagttttct
    14641 ttggctctat aatatttgta gtgggtaaat cccctatgga tattatggag c
//
LOCUS       DBEJHE010000040        14372 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC4 isolate 671759
            SAMN38261586-rid24793303.denovo.40, whole genome shotgun sequence.
ACCESSION   DBEJHE010000040 DBEJHE010000000
VERSION     DBEJHE010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261586
            Sequence Read Archive: SRR26833752
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 14372)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14372)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576136.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576136.1
            Genome Coverage       :: 109x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 19:48:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,067
            CDSs (total)                      :: 2,029
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 131
            CDSs (without protein)            :: 131
            Pseudo Genes (ambiguous residues) :: 0 of 131
            Pseudo Genes (frameshifted)       :: 64 of 131
            Pseudo Genes (incomplete)         :: 59 of 131
            Pseudo Genes (internal stop)      :: 46 of 131
            Pseudo Genes (multiple problems)  :: 32 of 131
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14372
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261586-rid24793303.denovo.40"
                     /strain="GPSC4"
                     /isolate="671759"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            463..1400
                     /locus_tag="ACL3EZ_001780"
                     /pseudo
     CDS             463..1400
                     /locus_tag="ACL3EZ_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000512061.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
     gene            1412..2305
                     /locus_tag="ACL3EZ_001781"
     CDS             1412..2305
                     /locus_tag="ACL3EZ_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001012086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0393309.1"
                     /translation="MNFVLSSLSEGLLWSIVAIGVYLTFRILDIADMTAEGAFPLGAA
                     VVVSQIQAGANPWLATLLALLAGMVAGLVSGMLHTKMKIPALLTGIVTLTGLYSINIK
                     IMGSVPNLSLGDSATVFKQLASLGLTNEGTVFSLSLACFLLVCLVLTLLMKTEIGLVL
                     RSTGDNIPMSEANGVNVDTMKIVGYMISNGLIALCGSLFAQNDGFSDVTSGTGTIVVG
                     LSSVIIAEVLIHDLTIGGRLLSIGIGAIVYRLIILNIYEIPNLDQNLVRLFNAILLAL
                     VLFAPELQKRLKIRGLKLRNE"
     gene            2318..3121
                     /locus_tag="ACL3EZ_001782"
     CDS             2318..3121
                     /locus_tag="ACL3EZ_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000157668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0393310.1"
                     /translation="MTSLLTLENIHKTFEAGTVNENHVLKGLDLEVEEGDFISVIGGN
                     GAGKSTLMNILAGNLSVDEGDLLLAGKSIKNLSVRKRAKDIARVFQDPKMGTASRLTI
                     EENMAIALRRGQKRGLGWGVKEKDRIQFQEALKELNIGLENRLKVDTQYLSGGQRQAL
                     TLVMTDLMKPKLLLLDEHTAALDPKTSQMVMDLTQKIVEHHQWTTLMITHDMNHAIEY
                     GNRLIMLYQGKIVVDVKGEEKKHLTVEDLMHLFQKNSGQSLVSDELVLG"
     gene            complement(3154..3864)
                     /gene="treR"
                     /locus_tag="ACL3EZ_001783"
     CDS             complement(3154..3864)
                     /gene="treR"
                     /locus_tag="ACL3EZ_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HGR0393311.1"
                     /translation="MKKYQQLFKQIQETIQNETYAVGDFLPSEHDLMEQYQVSRDTVR
                     KALSLLQEEGLIKKIREQGSQVVKEETVNFPVSNLTSYQELVKELGLRSKTNVVSLDK
                     IIIDKKSSLITGFPEFRMVWKVVRQRVVDDLVSVLDTDYLDMELIPNLTRQIAEQSIY
                     SYIENGLKLLIDYAQKEITIDHSSNRDKILMDIGKDPYVVSIKSKVYLQDGRQFQFTE
                     SRHKLEKFRFVDFAKRKK"
     gene            4049..6016
                     /gene="treP"
                     /locus_tag="ACL3EZ_001784"
     CDS             4049..6016
                     /gene="treP"
                     /locus_tag="ACL3EZ_001784"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015574 - trehalose transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015771 - trehalose transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HGR0393312.1"
                     /translation="MGKFEQEAKDLLQAIGGKENVTAVTHCATRMRFVLGDDKKANVK
                     AIESIPAVKGTFTNAGQFQVIIGNDVPIFYNDFTAVSGIEGVSKEAAKSAAKSNQNVV
                     QRVMTTLAEIFTPIIPALIVGGLILGFRNVLEGVHWSMLDGKTITESSQFWAGVNHFL
                     WLPGEAIFQFLPVGITWSVSRKMGTSQILGIVLGICLVSPQLLNAYAVASTPAADIAA
                     NWVWNFGYFTVNRIGYQAQVIPALLAGLSLSYLEIFWRKHIPEVISMIFVPFLSLIPA
                     LILAHTVLGPIGWTIGQGLSSVVLAGLTGPVKGLFGAIFGALYAPFVITGLHHMTNAI
                     DTQLIADAGGTALWPMIALSNIAQGSAVFAYYFMHRHDEREAQVSLPATISAYLGVTE
                     PALFGVNVKYIYPFVAGMTGSALAGMLSVTFNVTAASIGIGGLPGILSIQPQYMLPFA
                     GTMLVAIVVPMLLTFFFRKAGLFTKTEGDTNLQAEFVAQEEAEFVNHEPVELTSVEII
                     SPLTGQVKELSQATDPIFASGVMGQGLVIEPSQGELTSPVNGTVTVLFPTKHAIGIVS
                     DEGVELLIHIGMDTVGLDGKGFESLVVQGDHVTVGQQLIRFDMDVIKAAGLVTETPVI
                     ITNQDAYTATIPGTYPTTIQAGASLMVATRI"
     gene            6194..7819
                     /gene="treC"
                     /locus_tag="ACL3EZ_001785"
     CDS             6194..7819
                     /gene="treC"
                     /locus_tag="ACL3EZ_001785"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008788 - alpha,alpha-phosphotrehalase
                     activity [Evidence IEA];
                     GO_process: GO:0005991 - trehalose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HGR0393313.1"
                     /translation="MTLDKGKVVYQIYPKSYKDTTENGIGDFRGIIEKIPYLAKLGVD
                     MVWLNPFYPSPQRDNGYDISDYMAVDPLFGDMADFEEMVCVGKEHKIDFMLDMVLNHC
                     STEHEWFQKALAGDKYYQDFFFIQDQPTDWQSKFGGSAWAPFGDTGKYYLHLFDETQA
                     DLNWRNSNVRKELFKVVNFWRDKGVKGFRFDVINLIGKDEVSVDCPENEGKPAYTDKP
                     IVHNYLRMMNQATFGSDDSFMTVGEMSSTTMENCVLYSSPDRQELSMTFNFHHLKVDY
                     KDGQKWTLAPFDFEELKSLYHSWGKEMSDKDGWSALFWNNHDQPRALNRFVDIQNFRK
                     EGATMLAASIHLSRGTPYIYMGEEIGMIDPDYDSMADYVDVESLNAYQMLLEEGKSQQ
                     EAFQIIQAKSRDNSRIPMQWDASENAGFSTGTPWLKAGKSYKDINVENEIQGPIFTFY
                     QDLIRLRKEMPIISEGSYKPAFEDSKQVYAFERQFEDQKLLVLNNFYAKEVEIDLPAV
                     YQNGQILISNYEDAEVSEKILLKPYQTLAIYVN"
     gene            8075..8323
                     /locus_tag="ACL3EZ_001786"
     CDS             8075..8323
                     /locus_tag="ACL3EZ_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000364981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HGR0393314.1"
                     /translation="MDLLLAIVLIVLAFLGGALGGMYLVRKQIEKEFADNPRLNAEAV
                     RTLLSANGQKPSEAKVQQVYHQIIRQQKAALANNKKKK"
     gene            8530..9324
                     /gene="racE"
                     /locus_tag="ACL3EZ_001787"
     CDS             8530..9324
                     /gene="racE"
                     /locus_tag="ACL3EZ_001787"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008881 - glutamate racemase activity
                     [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HGR0393315.1"
                     /translation="MDNRPIGFLDSGVGGLTVVRELMRQLPHEEIVYIGDSARAPYGP
                     RPAEQIREYTWQLVNFLLTKDVKMIVIACNTATAVVWEEIKAQLDIPVLGVILPGASA
                     AIKSSQGGKIGVIGTPMTVQSDIYRQKIHDLDPDLQVESLACPKFAPLVESGALSTSV
                     TKKVVYETLRPLVGKVDSLILGCTHYPLLRPIIQNVMGPKVQLIDSGAECVRDISVLL
                     NYFEINRGRDAGPLHHRFYTTASSQSFAQIGEEWLEKEIHVEHVEL"
     gene            9321..10292
                     /locus_tag="ACL3EZ_001788"
     CDS             9321..10292
                     /locus_tag="ACL3EZ_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000182414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047429 - nucleoside triphosphate
                     diphosphatase activity [Evidence IEA];
                     GO_process: GO:0009143 - nucleoside triphosphate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-triphosphate diphosphatase"
                     /protein_id="HGR0393316.1"
                     /translation="MTNKIYEYKDDQDWYVGSYSIFGGVNSLSDYKTDFPLFEFSKIF
                     GDEEYGFPLSVTVLRYGSTYRLFSFVVDMLNQEMGRNLEVIQRHGALLLVENGQLLYV
                     ELPKEGVNVHDFFETSKVRETLLIATRNEGKTKEFRAIFDKLGYDVENLNDYPDLPEV
                     AETGMTFEENARLKAETISQLTGKMVLADDSGLKVDVLGGLPGVWSARFAGVGATDRE
                     NNAKLLHELAMVFELKDRSAQFHTTLVVASPNKESLVVEADWSGYINFEPKGENGFGY
                     DPLFLVGETGESSAELTLEEKNSQSHRALAVKKLLEVFPSWQSKPSL"
     gene            10268..10789
                     /locus_tag="ACL3EZ_001789"
     CDS             10268..10789
                     /locus_tag="ACL3EZ_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001118598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HGR0393317.1"
                     /translation="MAKQTIIVMSDSHGDSLIVEEVRDRYVGKVDAVFHNGDSELRPD
                     SPLWEGIRVVKGNMDFYAGYPERLVTELGSTKIIQTHGHLFDINFNFQKLDYWAQEEE
                     AAICLYGHLHVPSAWLEGKILFLNPGSISQPRGTIRECLYARVEIDDSYFKVDFLTRD
                     HEVYPGLSKEFSR"
     gene            10786..11247
                     /gene="cbpB"
                     /locus_tag="ACL3EZ_001790"
     CDS             10786..11247
                     /gene="cbpB"
                     /locus_tag="ACL3EZ_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000560721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0180001 - cyclic-di-AMP binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-di-AMP-binding protein CbpB"
                     /protein_id="HGR0393318.1"
                     /translation="MIAKEFETFLLGQEETFLTPAKNLAVLIDTHNADHATLLLSQMT
                     YTRVPVVTDEKQFVGTIGLRDIMAYQMEHDLSQEIMADTDIVHMTKTDVAVVSPDFTI
                     TEVLHKLVDESFLPVVDAEGIFQGIITRKSILKAVNALLHDFSKEYEIRCQ"
     gene            11244..11978
                     /gene="xerD"
                     /locus_tag="ACL3EZ_001791"
     CDS             11244..11978
                     /gene="xerD"
                     /locus_tag="ACL3EZ_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HGR0393319.1"
                     /translation="MRDRISAFLEEKQGLSVNSKQSYKYDLEQFLDMVGERISETSLK
                     IYQAQLANLKISAQKRKISACNQFLYFLYQKGEVDSFYRLELAKQAEKKTEKPEILYL
                     DSFWQESDHPEGRLLALLILEMGLLPSEILAIKVADINLDFQVLRISKASQQRIVTIP
                     TALLSELEPLMGQTYLFERGEKPYSRQWAFRQLESFVKEKGFPSLSAQVLREQFILRQ
                     IENKVDLYEIAKKLGLKTVLTLEKYR"
     gene            11978..12706
                     /locus_tag="ACL3EZ_001792"
     CDS             11978..12706
                     /locus_tag="ACL3EZ_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000351912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HGR0393320.1"
                     /translation="MDIKLKDFEGPLDLLLHLVSKYQMDIYDVPITEVIEQYLAYVST
                     LQAMRLEVTGEYMVMASQLMLIKSRKLLPKVAEVTDLGDDLEQDLLSQIEEYRKFKLL
                     GEHLEAKHQERAQYYSKAPTELIYEDAELVHDKTTIDLFLAFSNILAKKKEEFAQNHT
                     TILRDEYKIEDMMIIVKESLIGRDQLRLQDLFKEAQNVQEVITLFLATLELIKTQELI
                     LVQEESFGDIYLMEKKEESQVPQS"
     gene            12725..13294
                     /gene="scpB"
                     /locus_tag="ACL3EZ_001793"
     CDS             12725..13294
                     /gene="scpB"
                     /locus_tag="ACL3EZ_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HGR0393321.1"
                     /translation="MSTLAKIEALLFVAGEDGIRVRQLAELLSLPPTGIQQSLGKLAQ
                     KYEKDPDSSLALIETSGAYRLVTKPQFAEILKEYSKAPINQSLSRAALETLSIIAYKQ
                     PITRIEIDAIRGVNSSGALAKLQAFDLIKEDGKKEVLGRPNLYVTTDYFLDYMGINHL
                     EELPVIDELEIQAQESQLFGERIEEDENQ"
     gene            13281..14003
                     /locus_tag="ACL3EZ_001794"
     CDS             13281..14003
                     /locus_tag="ACL3EZ_001794"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HGR0393322.1"
                     /translation="MRINKYIAHAGVASRRKAEELIKQGLVTVNGQVVRELATTIKSG
                     DKVEVEGQPIYNEEKVYYLLNKPRGVISSVTDDKGRKTVVDLLPNVKERIYPVGRLDW
                     DTSGVLILTNDGDFTDEMIHPRNEIDKVYVARVKGVANKDNLRPLTRGLEIDGKKTKP
                     AVYEILKVDPVKNRSVVQLTIHEGRNHQVKKMFEAVGLQVDKLSRTRFGHLDLTGLRP
                     GESRRLNKKEISQLHTMAVTKK"
     gene            14003..14245
                     /gene="yidD"
                     /locus_tag="ACL3EZ_001795"
     CDS             14003..14245
                     /gene="yidD"
                     /locus_tag="ACL3EZ_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HGR0393323.1"
                     /translation="MKRILIAPVRFYQRFISPVFPPSCRFELTCSNYMIQAIEKHGFK
                     GVLMGLARILRCHPWSKTGKDPVPDHFSLKRNQEGE"
BASE COUNT         4088 a         2789 c         3375 g         4120 t
ORIGIN      
        1 ttttatggaa attataaaac tttttttgtt ggactgattt gaaaaacttt gaaagcttcc
       61 tgaaagaatt tttgaaaaat tttaaaaatt atgaaatgtt attgacaggt gatgaaaaag
      121 gtggtaggac aggaagcatc aaaaaagaaa gcagaaaaag aaatgaataa gagacaagcc
      181 gtaactatga atcaaaactt ttactttagc tactttagat agtgtttgta gacatgtcac
      241 catggatgca aacagttcaa gcaatttgtt tgtatctatg tggctaagat ttttgattgt
      301 ggtccatata gatgaatatc taaatggact agctaagttg taacttgtta ggttatttca
      361 agtatccgtt tagatagtat ctaggcggtt ttttgtttta tcttttctga gaaggagttt
      421 cattatgaaa gttgttcgaa aatcactagc cccctcttgg tagtggggct cctcttgact
      481 tctctgatca gtttgcatca gttgaaggca gataagaaaa agatgtcttt cgtatcggta
      541 tttcgcaatt tattacccac cagtccttat acgctactag agaaggattt gtggatgagc
      601 tggccaaaca aggctatgtt gagggggaaa atattgagat tgatttgcaa aatgcacagg
      661 gagaacaaag aaatctaaaa acgatttccc agcaactagc agaatccagc gatgtcgttc
      721 tagccatcgc aaggccttct gctcagagct tggccaatac gacgcaaacg acaccagtta
      781 tcttttcagc tgtaacagac ccagtcagtg ccaagttggt tgagtcaaga gaacatcctg
      841 ggggcaatgt aactgggaca agcgatcagt catcagatgc catttcaacc caaatcaatt
      901 tgataaagaa agtgttgcca aaggctaaaa cgattggaat cctctatact cagagcgagc
      961 ccaattcggt tgttcaaaag gatgaagcta agcgacttct gaaagaaaaa ggctttaccg
     1021 ttgttgaaaa aacaatcttg gacagtaata acgtcaaggc ggcagcagag agtttgatgg
     1081 cagaggtgga tatggttttt gtcccaactg ataatatcat ttcgttaacc atggaaacag
     1141 ttaagcaggt ttctattaaa cacaaggttc cagtattcgg tggttcaaca gaaatgattg
     1201 ctgttggtgg cttgtataac tacggaacca attatgaaga attggtacgt cagacagctc
     1261 gcatgctgat tcgtgtttta aaaggtgaga aaccagaaaa tatagcagtt gagttgcctg
     1321 aaaaactgga attgcatacc aatcaagaaa tggcagatgc attgggaatt gatattagta
     1381 agttagaagg caaggaataa ggaggattaa gatgaatttt gtgttatcta gtttatcaga
     1441 aggtttgttg tggtcgattg tggcgattgg ggtctacttg actttccgta ttttggatat
     1501 tgcggatatg actgctgagg gagcctttcc tctgggggca gcagtcgttg tatcacagat
     1561 acaggcaggg gcaaatcctt ggcttgcgac tttacttgct ttgctggcag gtatggtagc
     1621 aggtcttgta tcaggaatgc tccacaccaa gatgaaaatc ccagctctct tgacagggat
     1681 tgtgaccttg acagggctct attcaatcaa tattaaaatc atgggcagtg tacccaatct
     1741 ttccttggga gattctgcaa ccgtctttaa acagttggcg agcttgggtc tgacaaatga
     1801 aggaactgtt ttctcactta gtttggcctg ttttttactt gtttgtttgg tcttgaccct
     1861 tttgatgaaa acagagattg gcttggtctt gcgttcgact ggggataata tcccgatgag
     1921 tgaggccaat ggagtcaatg tagacaccat gaagattgtt ggttacatga tttcaaacgg
     1981 tttgattgct ctatgtggtt ccttgtttgc ccaaaatgat ggattttcag atgtgacttc
     2041 tgggacagga accattgttg ttggtttgag ctcggtgatt attgcggaag tcttgataca
     2101 cgacttgacc attggaggcc gcttattatc catcggaatc ggtgctattg tttaccgttt
     2161 gattatttta aatatctatg aaattccaaa tctagatcaa aacttggtac gtctctttaa
     2221 tgcaatcttg ctcgctttgg ttttatttgc accagaattg caaaagagat taaagattcg
     2281 tggtctgaaa ttgagaaatg aataggagga gaaagttatg acaagtttgt taacacttga
     2341 aaatattcac aagacatttg aagcagggac ggtcaatgag aaccatgtcc tcaaaggatt
     2401 agatttagag gttgaagagg gagattttat ctctgtgatt ggtggaaatg gagcaggaaa
     2461 atccactttg atgaatatct tggctggcaa tctatcggtg gacgaagggg accttctact
     2521 ggcagggaaa tccattaaaa atctgagtgt cagaaagaga gccaaggata ttgcccgtgt
     2581 ttttcaagat cctaagatgg gaacagcttc tcgtttgacg attgaggaga atatggctat
     2641 tgccttgaga cgcgggcaga agagagggct tggttggggc gtgaaggaga aggatagaat
     2701 ccagttccaa gaggccttga aggagttgaa tattggtctt gaaaaccgct taaaagtaga
     2761 tactcaatat ctctcaggag gacaaagaca ggctttgact ctagtcatga cagatctgat
     2821 gaaaccaaaa cttttacttt tggatgaaca tactgcggca cttgacccga aaaccagtca
     2881 aatggtgatg gacttgacgc aaaagattgt ggagcaccat cagtggacga ctttgatgat
     2941 tacccatgat atgaatcatg cgattgagta cggcaatcgt ctcattatgc tctatcaagg
     3001 caagatagtg gtggatgtca agggagaaga gaaaaagcat ctgacagttg aagaccttat
     3061 gcatctcttc cagaaaaata gtggccaaag tctggtcagt gatgaattag ttttgggata
     3121 aagaaaaagg ctgagatctg gtgtctcagt cttttatttc ttgcgttttg caaaatctac
     3181 aaatctaaat ttctctaact tatggcgact ttcggtaaac tgaaattggc gtccgtcttg
     3241 gagatagact tttgatttaa tcgaaacgac ataagggtct ttgccaatgt ccatgagaat
     3301 cttgtctcgg ttgcttgagt ggtcaatggt gatttccttc tgagcataat caataaggag
     3361 tttgaggcca ttttctatat aagaatagat agactgctca gcaatttggc gagtgagatt
     3421 tggaattagt tccatatcca gatagtccgt atccagaacg gataccagat catccaccac
     3481 acgctggcgg accaccttcc aaaccatccg aaactctggg aaaccggtta tcagtgagga
     3541 ttttttatca ataataatct tgtccagact gaccacgttg gttttagagc gcagtccaag
     3601 ttctttaact agttcttggt agctggttag gttggataca gggaaattga cggtttcttc
     3661 tttgacgact tgagaacctt gctctcttat ctttttgatc aatccttcct cttggaggag
     3721 agacagggcc tttcggacgg tatcacgact cacttgatat tgctccataa ggtcgtgctc
     3781 gctaggaagg aaatctccga cagcgtaagt ctcgttttga atggtttctt ggatttgctt
     3841 aaataattgt tggtatttct tcattttgcc tgctttaata ggtttttagt ctagtttaat
     3901 gaacacctgt atctatttta ccatacaagt gctagaaaat ttacaaaaaa acaccctttt
     3961 tataccaaac aagttgcaga caagtttggt atcgtttaca atatacttat caaatcaaac
     4021 ttgctttgac aagtataagg agaatcaaat gggaaaattt gaacaagaag ccaaagatct
     4081 gcttcaggca attggaggca aagaaaatgt gactgccgta actcactgtg cgacacggat
     4141 gcgctttgtt ttaggagatg ataagaaggc taatgttaaa gctatcgagt caattccagc
     4201 tgttaaagga acttttacaa atgcaggtca atttcaggta atcattggaa atgacgtgcc
     4261 catcttttat aatgatttta cagccgtttc aggtattgag ggtgtttcca aagaagcagc
     4321 caagtctgca gctaagagta atcaaaacgt ggtccaacgt gttatgacca ctctggcgga
     4381 gatttttact ccgattattc cagccttgat agtcggagga ttgatcctcg gtttccgtaa
     4441 tgtcttggaa ggtgtccatt ggtcgatgtt ggatggcaag accatcacag aatcctctca
     4501 gttttgggca ggtgtcaatc acttcctctg gttgcctggt gaagctatct tccagttctt
     4561 accagtaggg attacttggt ctgtttctcg taagatggga accagccaaa ttttgggaat
     4621 tgttctcgga atctgtttgg tatcgcctca gttgctcaat gcctatgcgg ttgcttcaac
     4681 gccagcagct gatatcgcgg caaactgggt ttggaatttt ggctatttta ctgttaatcg
     4741 tatcggttac caagcccaag ttatcccagc cttgcttgca ggtttgagtc tgtcttatct
     4801 tgaaatcttc tggcgcaagc atatcccaga agtcatttct atgatttttg tacctttctt
     4861 gtcattgatt ccagccttga ttttggctca tactgttttg ggaccaatcg gttggacaat
     4921 tggacaagga ctttcatcag ttgtcttggc aggtttaact ggtccagtta aagggctctt
     4981 cggtgcaatt tttggtgccc tctacgctcc atttgtcatc acaggtctgc accatatgac
     5041 caatgccatt gatacacaat tgattgcgga tgctggtggc actgccctat ggccaatgat
     5101 tgctctttct aatattgctc aaggctcagc cgtgtttgcc tattatttca tgcatcgcca
     5161 tgatgagcgt gaggctcagg tttcacttcc tgcaaccatt tcagcctatc tcggtgttac
     5221 agaaccagct ctttttgggg ttaacgtaaa atatatttat ccatttgttg ctgggatgac
     5281 tggttcagcc cttgcaggca tgttatccgt tacttttaat gtaactgcgg cttctattgg
     5341 tatcggtggt ttgccaggta ttctctctat tcaacctcaa tacatgctgc catttgcagg
     5401 aactatgcta gttgcgattg ttgttccaat gctcttgact ttcttcttcc gcaaggctgg
     5461 tctctttaca aaaacagagg gcgatacgaa cttgcaggca gaattcgttg ctcaagaaga
     5521 agcagaattt gtgaaccatg aaccagtaga acttacttcg gtagaaatta tcagcccact
     5581 aactggccaa gtgaaagaat tgagtcaagc gacggatcct atttttgcat caggtgtcat
     5641 ggggcaaggt ctggtcattg aaccaagcca aggtgagttg acctctccag ttaatgggac
     5701 agtgacggtt cttttcccta ccaagcatgc catcggcatt gtctctgacg agggagttga
     5761 attgctcatc cacatcggta tggatacagt aggtcttgat ggcaaaggtt ttgaaagtct
     5821 tgtagtccaa ggagatcacg ttacagttgg tcagcaactg attcgttttg atatggatgt
     5881 cattaaggct gcaggtctgg tgacagaaac tcctgttatc atcaccaacc aagatgctta
     5941 tacagcgact attcccggaa cttatccgac aacgattcaa gctggagcat ctctcatggt
     6001 cgctacacga atctaatact cttcgaaaat ctcttcaaac cacgtcagct ctatctgcaa
     6061 cctcaaaaca gtgttttgag caacctgtgg ctagcttcct agtttgctct ttgattttca
     6121 ttgagtataa ttgaaatagc acaaataggg acggaagact gcttcctccc ttttatcaga
     6181 aaaggagaaa cagatgacac ttgataaagg aaaagtagtc tatcaaatct atccaaaatc
     6241 ttacaaagac accactgaaa acggtattgg ggatttccgt gggattatcg aaaaaattcc
     6301 ctatttagcc aaactaggcg tggatatggt ctggctcaat ccattctatc caagccctca
     6361 acgggataat ggttacgata tttcagatta tatggcagtg gatcctcttt ttggtgatat
     6421 ggctgatttt gaggaaatgg tgtgtgtcgg taaagagcac aagattgact ttatgctgga
     6481 catggtactt aatcattgtt cgacagagca tgaatggttt cagaaagccc tagctggtga
     6541 taagtattat caagactttt tcttcatcca agaccaacca acagattggc agtctaagtt
     6601 tggtggttct gcatgggcgc ctttcgggga tactgggaaa tactatcttc acctatttga
     6661 tgagacccag gctgacctta actggcgcaa ttccaatgtc cgtaaggagc ttttcaaggt
     6721 tgttaatttc tggcgcgaca agggtgtcaa aggtttccga tttgatgtga tcaatttgat
     6781 cggtaaggac gaggtttcag tggactgtcc tgaaaatgaa gggaagccag cttatacaga
     6841 caaacccatc gttcataact atttgcgtat gatgaaccaa gccacttttg gatctgacga
     6901 tagctttatg acagttgggg aaatgtcttc taccaccatg gaaaactgtg tcctctattc
     6961 gtcgcctgat cgtcaggaat tatccatgac ctttaatttt catcacctca aggtggacta
     7021 taaggatgga caaaagtgga ccttggctcc ctttgatttt gaagagttga agagtcttta
     7081 ccatagttgg ggtaaggaaa tgagtgataa agacggttgg agtgccctct tttggaacaa
     7141 tcacgatcaa ccacgtgcct tgaaccgttt tgtcgatatt caaaacttcc gcaaggaagg
     7201 agccaccatg ctagcggcca gcattcacct gtcacgtggg acaccttata tctacatggg
     7261 tgaggaaatc gggatgattg acccagacta tgattctatg gctgattatg tggatgtcga
     7321 atcgcttaat gcctatcaga tgctcttaga agaaggaaag agtcagcaag aagccttcca
     7381 gattattcaa gctaagtcgc gtgataattc acgcattccc atgcagtggg atgcttcgga
     7441 aaatgcagga ttttcaacag gcactccttg gttgaaagct ggtaaatcct ataaagacat
     7501 caatgtagaa aatgaaatcc agggtccgat ttttaccttc tatcaagact tgattcgact
     7561 gcgtaaggaa atgccaatca tttcagaagg aagttacaaa ccagcctttg aagatagcaa
     7621 acaagtctac gcttttgaac gccagtttga ggatcaaaag ttactagtgc tcaataactt
     7681 ttatgctaaa gaagtggaaa tcgacttgcc agcagtctac caaaatggac agattttgat
     7741 ttcaaactat gaagatgcag aagtgtctga gaaaattcta ctcaaaccct atcaaacact
     7801 ggctatttat gtaaattaat actcttcgaa aatctcttca aaccgtgtca gttttatctg
     7861 caacctcaaa gcggtgcttt gagcaacctg tggctagctt cctagtttgc tctttgattt
     7921 tcattgagta taaacttagc aaggagacct ctttttcaga aaagcagggt tctttttgct
     7981 gtctattcca tccttgaaag tgtagaacaa actggtcagg gtggctagtt tgtggtataa
     8041 tgaaagggac tcaaaaagaa acaggagaaa aatgatggat ttacttttag caattgtatt
     8101 gattgtgcta gcttttctag gaggagctct tggaggaatg tacttggttc gtaagcaaat
     8161 cgaaaaagaa tttgctgaca acccacgttt gaatgctgaa gcagttcgta ctcttttgag
     8221 tgcaaatggt caaaaaccaa gcgaagctaa ggtacaacaa gtttaccacc aaatcatccg
     8281 ccaacaaaag gcagcccttg ctaacaataa aaagaaaaaa taaataagga aaagtctggg
     8341 atgaaagttc cagacttctc actatgttgg ttatggttta gggatgagac tttttccttg
     8401 cattctattg atatttgatt atgattaaga gagaggtagt tgacattcta tcaagctgtc
     8461 ggtcagttcg ttcagtacaa ggaatcataa tgaacgatca atcagaaaaa agactagaaa
     8521 gaagactgta tggataatcg accaattggt tttttggatt cgggtgtcgg gggcttgacc
     8581 gttgtgcgcg agctcatgcg ccagcttccc catgaagaaa tcgtctatat tggagattcg
     8641 gcgcgggcgc cctatggccc ccgtcctgct gagcaaattc gtgaatatac ttggcagctg
     8701 gtcaactttc tcttgaccaa ggatgtcaaa atgattgtca ttgcttgtaa cactgcgact
     8761 gcggtcgtct gggaagaaat caaggctcaa ctagatattc ctgtcttggg tgtaattttg
     8821 ccaggagctt cggcagccat caagtccagt caaggtggga aaatcggagt gattggaacg
     8881 cccatgacgg tacaatcaga catataccgt cagaaaatcc atgatctgga tcccgactta
     8941 caggtggaga gcttggcctg tcccaagttt gctcccttgg ttgagtcagg tgccctgtca
     9001 accagtgtta ccaagaaggt ggtctatgaa accctgcgtc ccttggttgg aaaggtggat
     9061 agcctgattt tgggctgtac tcattatcca ctccttcgcc ctattatcca aaatgtgatg
     9121 gggccaaagg ttcagctcat cgatagtggg gcagagtgcg tacgggatat ctcagtctta
     9181 ctcaattatt ttgaaatcaa tcgtggtcgc gatgctggac cactccatca ccgtttttac
     9241 acaacagcca gtagccaaag ttttgcacaa attggtgaag aatggctgga aaaagagatt
     9301 catgtggagc atgtagaatt atgacaaata aaatttatga atataaggat gaccaggact
     9361 ggtatgttgg gtcttatagt atttttggtg gcgttaacag tttgagcgac tataagacag
     9421 attttcctct gtttgaattc tccaaaatat ttggagatga agagtatggt ttcccgcttt
     9481 cagttactgt tttacgctat ggttctacct accgtttgtt ctcctttgtg gtagatatgc
     9541 ttaatcaaga aatgggacga aacttggaag ttattcaacg tcatggggcc ctgctcttgg
     9601 ttgaaaatgg gcaactcttg tatgtagaat tgcctaaaga aggggtcaat gttcatgatt
     9661 tctttgagac aagcaaggtc agagaaacct tgttgattgc gactcgtaac gaaggcaaaa
     9721 ccaaggaatt ccgagctatc tttgataagt taggctacga tgtggaaaat cttaatgact
     9781 accctgacct gcctgaagta gcagaaacag gtatgacctt tgaagaaaat gcccgcctta
     9841 aggcagaaac catttctcaa ttaacgggta agatggtttt ggcagatgat tctggtctca
     9901 aagtcgatgt ccttggtggc ttaccaggcg tctggtcagc tcgtttcgca ggtgtgggag
     9961 caactgaccg tgaaaataat gccaaactct tgcacgaatt ggccatggtc tttgaactca
    10021 aggaccgctc ggctcagttc cacacaaccc tagtcgtagc cagcccaaat aaggaaagtt
    10081 tagttgttga agcagactgg tcaggttata ttaactttga acctaagggt gaaaatggct
    10141 ttggctatga tcccctcttc cttgtaggag agacaggtga gtcatcagct gaattaaccc
    10201 tagaagaaaa aaatagtcaa tctcaccgtg ccttagccgt taagaaactt ttggaggtat
    10261 ttccatcatg gcaaagcaaa ccatcattgt aatgagcgat tcccatggcg atagcttgat
    10321 tgtggaagaa gtccgtgatc gctatgtggg caaagtcgat gccgtttttc ataacggcga
    10381 ttctgaacta cgtccggatt ctccactttg ggagggcatc cgcgttgtta aagggaacat
    10441 ggacttctac gccggctacc cagaacgtct ggtgactgag cttggttcga ccaagattat
    10501 ccaaactcat ggtcacttgt ttgacatcaa tttcaacttt caaaagttgg actactgggc
    10561 tcaggaggaa gaggccgcta tctgcctcta tggtcacttg catgtgccaa gtgcttggtt
    10621 ggaaggcaag atcctctttc taaatccagg ttctatcagt caaccacgag gtaccatcag
    10681 agaatgtctc tatgctcgtg tggagattga tgatagttac ttcaaagtgg actttttgac
    10741 acgagatcac gaggtgtatc caggtttgtc caaggagttt agccgatgat tgccaaggag
    10801 tttgagactt tcttgttggg gcaggaggaa acttttttga cccctgctaa aaatctagct
    10861 gtgttgattg atacccacaa tgcggatcat gcgaccctct tgctcagtca gatgacctat
    10921 acccgtgttc ccgttgtgac agatgaaaaa cagtttgttg ggacgattgg actcagagat
    10981 attatggctt atcagatgga gcatgacttg agccaagaaa tcatggcgga tacggatatc
    11041 gttcatatga caaaaacgga cgtagcggtt gtttcgcctg atttcaccat tacggaggtc
    11101 ttgcacaagc tagtagatga gtccttctta ccggtcgtgg atgcagaggg tattttccaa
    11161 gggattatta cgcgcaagtc catcctcaag gccgttaatg ccctcttgca tgactttagt
    11221 aaggaatatg agattcgatg ccaatgagag acaggatttc agccttttta gaggaaaagc
    11281 agggcttgtc tgtcaattcc aagcagtcct ataagtatga tttggagcaa tttttagaca
    11341 tggtaggtga gcggatttct gagaccagtc tcaagattta ccaagcccag ctagccaatc
    11401 taaaaatcag cgcccagaag cgaaagattt cggcctgtaa ccaatttcta tactttctct
    11461 atcaaaaagg agaggtggac agcttttacc gcttggaatt agccaaacaa gctgaaaaga
    11521 agacggaaaa gccagagatt ctatacctag actctttttg gcaggaaagc gaccatccag
    11581 agggccgctt gctagcgctc ttaatcctag aaatggggct cttgcccagt gagattttag
    11641 ccatcaaggt tgcggacatc aatctggatt ttcaggtgct gcgaatcagc aaggcttccc
    11701 aacagaggat tgtcaccatt cccacggcct tgctttcaga attggaaccc ttgatggggc
    11761 agacctatct ttttgaaaga ggagagaaac cctattctcg tcagtgggcc tttcgtcagt
    11821 tagaatcttt tgtcaaggag aaaggttttc catccttatc agctcaagtc ttacgtgaac
    11881 agtttattct aagacaaata gaaaacaagg tcgatttgta cgaaattgca aaaaaattag
    11941 gattaaaaac agtcctgacc ttagaaaaat atagataatg gatattaaat taaaagattt
    12001 tgaaggaccc ctggacttgc tcttgcatct ggtttctaag taccagatgg atatctacga
    12061 tgtgcccatt acggaagtca tcgaacagta tctagcctat gtctcaaccc tgcaggccat
    12121 gcgtctggaa gtgacgggtg agtacatggt catggctagt cagctcatgc tgattaagag
    12181 tcgtaaactc cttccgaagg tagcagaagt gacagacttg ggggatgacc tggagcagga
    12241 cctcctctct caaatcgaag aatatcgcaa gttcaagctc ttgggtgagc acttggaagc
    12301 caagcaccaa gaacgggccc agtattattc caaagcgccg acagagttga tttacgaaga
    12361 tgcggagctt gtgcatgaca agacgaccat tgacctcttt ttggcttttt caaatatcct
    12421 agccaagaaa aaagaggagt ttgcacaaaa tcacacgacg atcttgcggg atgagtataa
    12481 gattgaggac atgatgatta tcgtgaaaga gtccttgatt ggacgagatc aattgcgctt
    12541 gcaggatttg ttcaaggaag cccagaatgt ccaagaggtc atcaccctct ttttggcaac
    12601 cctagagtta atcaaaaccc aggagctgat cctcgtgcaa gaggagagtt ttggagatat
    12661 ctatctcatg gaaaagaagg aagaaagtca agtgcctcaa agctagactt gatagagagg
    12721 aaagatgagt actttagcaa aaatagaagc gctcttgttt gtagcgggtg aagatgggat
    12781 tcgggtccgc cagttagctg aactcctctc tctgccaccg acaggcatcc agcaaagttt
    12841 aggaaaatta gcccagaagt atgaaaagga cccagattcc agtttggctt tgattgagac
    12901 aagtggtgct tatagattgg tgaccaagcc tcaatttgca gagattttga aggaatactc
    12961 taaggcgcct atcaaccaga gcttgtctcg ggctgccctt gagaccttgt ccattattgc
    13021 ctacaaacag ccgattacgc ggatagaaat tgatgccatc cgtggagtta actcgagtgg
    13081 agccttggca aagttgcagg cttttgacct gataaaggaa gacgggaaaa aggaagtatt
    13141 ggggcgcccc aacctctatg tgactacgga ttatttccta gattacatgg ggataaacca
    13201 tttagaagaa ttaccagtga ttgatgagct tgagattcaa gcccaagaaa gccaattatt
    13261 tggtgaaagg atagaagaag atgagaatca ataagtatat tgcccacgca ggtgtggcca
    13321 gtaggagaaa agcagaagag ctgattaagc aaggcttggt gacggttaac ggccaagtgg
    13381 tgcgtgaact agcaaccact atcaagtcag gcgacaaggt cgaagttgaa ggtcaaccta
    13441 tctacaacga agaaaaggtc tactatctgc ttaacaaacc acgcggtgtg atttccagtg
    13501 tgacagatga taagggtcgc aagacggttg tcgacctctt gcccaatgtc aaagagcgta
    13561 tttaccctgt gggtcgtttg gactgggata catcaggtgt cttgattttg accaatgatg
    13621 gggactttac agacgagatg attcaccctc gtaatgagat tgacaaggtt tatgtcgcgc
    13681 gtgttaaagg tgtggccaat aaggacaatc tccgcccctt gacccgtggt cttgagattg
    13741 atggtaagaa aaccaagcca gctgtttatg aaattctcaa agtggaccca gtcaaaaatc
    13801 gctctgtggt gcagttgacc atccatgaag ggcgtaacca tcaggttaaa aagatgtttg
    13861 aagctgttgg tctccaagta gataagttgt ctcggactcg tttcggacac ctagacttga
    13921 caggactccg tccaggagaa tcccgtcgtc ttaataaaaa agaaatcagc caactacaca
    13981 ccatggctgt aactaagaaa taatgaaacg aattttaata gcgcctgtgc gcttttacca
    14041 acgttttatc tcaccagtct ttccaccctc ttgtcgcttt gagctgactt gttccaacta
    14101 catgattcag gctattgaaa aacatggttt taagggggta ttgatgggct tggctcggat
    14161 tttacgttgt catccctggt cgaaaacagg taaggacccc gttccagacc acttttccct
    14221 taaacgaaat caagaagggg aatgaggtgg ggtaaataga tttcaaaatg ataaaaacgc
    14281 atcctatcag gtttgagtaa acttgatagg atgcgtttta gaatgtcaaa attttatact
    14341 cttcgaaaat ctcttcaaac cgcgtcagct tt
//
LOCUS       DBEJHE010000041        14310 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC4 isolate 671759
            SAMN38261586-rid24793303.denovo.41, whole genome shotgun sequence.
ACCESSION   DBEJHE010000041 DBEJHE010000000
VERSION     DBEJHE010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261586
            Sequence Read Archive: SRR26833752
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 14310)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14310)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576136.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576136.1
            Genome Coverage       :: 109x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 19:48:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,067
            CDSs (total)                      :: 2,029
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 131
            CDSs (without protein)            :: 131
            Pseudo Genes (ambiguous residues) :: 0 of 131
            Pseudo Genes (frameshifted)       :: 64 of 131
            Pseudo Genes (incomplete)         :: 59 of 131
            Pseudo Genes (internal stop)      :: 46 of 131
            Pseudo Genes (multiple problems)  :: 32 of 131
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14310
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261586-rid24793303.denovo.41"
                     /strain="GPSC4"
                     /isolate="671759"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(10..1299)
                     /gene="hisS"
                     /locus_tag="ACL3EZ_001796"
     CDS             complement(10..1299)
                     /gene="hisS"
                     /locus_tag="ACL3EZ_001796"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004821 - histidine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006427 - histidyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HGR0393324.1"
                     /translation="MKLQKPKGTQDILPAESAKWQYVEGFAREIFKRYNYAEVRTPIF
                     EHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRSYVENKLFAPEVQK
                     PSKFYYMGPMFRYERPQAGRLRQFHQIGVECFGSSNPATDVETIAMAAHFLKEIGIQG
                     VKLHLNTLGNPESRAAYRQALIDYLTPLKETLSKDSQRRLEENPLRVLDSKEKEDKEA
                     VENAPSILDFLDEESQAHFDAVRQMLENLGVDYIIDTNMVRGLDYYNHTIFEFITEIE
                     GNDLTVCAGGRYDGLVSYFGGPETAGFGFGLGVERLLLILEKQGVTLPIENALDVYIA
                     VLGEGANIKALELVQALRQQGFKAERDYLNRKLKAQFKSADVFVAKTLITLGESEVES
                     GQVTVKNNQTREEVQVSLETISQNFSEIFEKLGFYTQ"
     gene            complement(1377..2612)
                     /locus_tag="ACL3EZ_001797"
     CDS             complement(1377..2612)
                     /locus_tag="ACL3EZ_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HGR0393325.1"
                     /translation="MKLLFRNLAYRILTLSRFFNAFGASIFNLVFIVYASTLSQASFA
                     VAMANIVMILPTLFTVFVGIRADYTRDKVKWMVYSGLFQAVLFFLAALVVQQASLFAF
                     SSLCLINVISDFAGGLRMPLIKEKVAEDDLMEAYSFSQFITYISAIGGQAFGVWLLAL
                     SVNNFSLVAGINACFFLVSATILFLGKSKLSLSMSSADGENLKNEKLSIKDQFLTIYR
                     NLRLVFLKSGQKNFGFMLFAVLLINSLGGALGGIYNIFFLSHSLLNFSYTEALFINQF
                     CVLVAIIISSLTGNDYFGKQSLPRLMMWATVGLSLVGLANLFNQVVLGLLFLFFTLYV
                     SGKVQPKISAMLMKNLAPEVLARTSNFLGLLFTLSIPVGTACFSLVAVWNIQLTWMLF
                     VGLSLLAIFLTILNLKNDI"
     gene            complement(2803..3654)
                     /gene="rgg"
                     /locus_tag="ACL3EZ_001798"
     CDS             complement(2803..3654)
                     /gene="rgg"
                     /locus_tag="ACL3EZ_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434947.1"
                     /note="Rgg, as the term is used in Streptococcus
                     pneumoniae, is the lone quorum-sensing system
                     transcriptional regulator related to proteins Rgg1, Rgg2,
                     Rgg3, and Rgg4 of Streptococcus pyogenes; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     Rgg"
                     /protein_id="HGR0393326.1"
                     /translation="MEQIGKVFRQLRESRNISLRQATGGQFSPSMLSRFETGQSELSV
                     EKFLFALENISASVEEILFLARGFQYDTDSELRKEITDVLEPKNIAPLEDLYRREYQK
                     HAHSHNKQKHILNAIIIKSYMKSIDERVDLTAEEGKVLHDYLFSTEIWGIYELNLFSV
                     SSPFLSVSLFTRYVREMVRKSDFLMEMSGNRNLFHTILLNGFLASIECEEFTNAYYFK
                     RVIEEHFYKGNETYFRIVYLWAEGLLDSKQGRVKEGQKKMEDAVRIFEMLGCNKSAEY
                     YRNTTEC"
     gene            3778..4119
                     /locus_tag="ACL3EZ_001799"
     CDS             3778..4119
                     /locus_tag="ACL3EZ_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003080443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HGR0393327.1"
                     /translation="MRDDIKINDRALALQDQIIEKLEKVFDTDVELDVYNLGLIYEIN
                     LDETGLCKIVMTFTDTACDCAESLPIEIVAGLKQIEGIKDIKVEVTWSPAWKITRISR
                     YGRIALGLPPR"
     gene            4183..4392
                     /locus_tag="ACL3EZ_001800"
     CDS             4183..4392
                     /locus_tag="ACL3EZ_001800"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0393328.1"
                     /translation="MKIKGQTRKLAAGCSKHCFEVMDRTDEVSSKYCFEVMDRTDEVS
                     SKYCFEVVDRTDEVSNHTYGKATLT"
     gene            complement(4418..6121)
                     /gene="ilvD"
                     /locus_tag="ACL3EZ_001801"
     CDS             complement(4418..6121)
                     /gene="ilvD"
                     /locus_tag="ACL3EZ_001801"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004160 - dihydroxy-acid dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009082 - branched-chain amino acid
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HGR0393329.1"
                     /translation="MTELDKRHRSSIYDSMVKSPNRAMLRATGMTDKDFETPIVGVIS
                     TWAENTPCNIHLHDFGKLAKEGVKSAGAWPVQFGTITVADGIAMGTPGMRFSLTSRDI
                     IADSIEAAMSGHNVDAFVAIGGCDKNMPGSMIAIANMDIPAIFAYGGTIAPGNLDGKD
                     IDLVSVFEGIGKWNHGDMTAEDVKRLECNACPGPGGCGGMYTANTMATAIEVLGMSLP
                     GSSSHPAESADKKEDIEAAGRAVVKMLELGLKPSDILTREAFEDAITVTMALGGSTNA
                     TLHLLAIAHAANVDLSLEDFNTIQERVPHLADLKPSGQYVFQDLYEVGGVPAVMKYLL
                     ANGFLHGDRITCTGKTVAENLADFADLTPGQKVIMPLENPKRADGPLIILNGNLAPDG
                     AVAKVSGVKVRRHVGPAKVFDSEEDAIQAVLTDEIVDGDVVVVRFVGPKGGPGMPEML
                     SLSSMIVGKGQGDKVALLTDGRFSGGTYGLVVGHIAPEAQDGGPIAYLRTGDIVTVDQ
                     DTKEISMAVSEEELEKRKAETTLPPLYSRGVLGKYAHIVSSASRGAVTDFWNMDKSGK
                     K"
     gene            complement(6354..7286)
                     /locus_tag="ACL3EZ_001802"
     CDS             complement(6354..7286)
                     /locus_tag="ACL3EZ_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HGR0393330.1"
                     /translation="MMRSTKELRHVYRDFLLEANQSYSDIVVLEADLSSSMATNNLEK
                     DFGDRYVNVGIMEAEMVGLAAGLSIQGFRPYLHTFGPFASRRVFDQLFISLGYAQLDA
                     TVIGSDAGVTAEMNGGTHMPFEEIGLLRLIPKSIIFEATDDIQFREILNQTLDLKGLK
                     YIRTIRKAPVPVYQGGEDFSKGYIELRHGEDLVIVASGIMVAPSIRVADELSKLGYSV
                     SVIDLFRIKPIPEQIKTMLSGKTIFTVENHNQIGGIGSSLCELFSDDGMTKIHRMGVQ
                     ERFGQVGKMDYLLNEYGLSESNIKEKVLEIYNAR"
     gene            complement(7283..8140)
                     /locus_tag="ACL3EZ_001803"
     CDS             complement(7283..8140)
                     /locus_tag="ACL3EZ_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HGR0393331.1"
                     /translation="MILSKNREDELRKFATNIRLNTLRTLNHLGFGHYGGSLSIVEVL
                     AVLYGEIMPMTPEIFAARDRDYFILSKGHGGPALYSTLYLNGFFDKEFLYSLNTNGTK
                     LPSHPDRNLTPGIDMTTGSLGQGISVATGLAYGQRIRKSPFYTYAIVGDGELNEGQCW
                     EAIQFASHQQLSNLIVFVDDNKKQLDGFTKDICNPGDFVEKFSAFGFESIRVKGSDIR
                     EIYEGIVQLKQSNNSSPKCIVLDTIKGQGVQELEEMKSNHHLRPTVEERQMLTSVVER
                     LSQELEETE"
     gene            complement(8144..9490)
                     /locus_tag="ACL3EZ_001804"
     CDS             complement(8144..9490)
                     /locus_tag="ACL3EZ_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HGR0393332.1"
                     /translation="MMKFILDIVSTPAILVALIAILGLVLQKKKLPDIIKGGIKTFVG
                     FLVVSGGAGIVQNSLNPFGTMFEHAFHLSGVVPNNEAIVAVALTTYGSATALIMFAGM
                     VFNILIARFTRFKYIFLTGHHTLYMACMIAVILSVAGFTSLPLILLGGLALGIIMSIS
                     PAFVQKYMVQLTGNDKVALGHFSSLGYWLSGFTGSLIGDKSKSTEDIKFPKSLAFLRD
                     STVSITLSMAVIYIIVAIFAGSEYIEKEISSGTSGLVYALQLAGQFAAGVFVILAGVR
                     LILGEIVPAFKGISERLVPNSKPALDCPIVYTYAPNAVLIGFISSFVGGLVSMAIMIA
                     SGTVVILPGVVPHFFCGATAGVIGNASGGVRGATIGAFLQGILISFLPVFLMPVLGGL
                     GFQGSTFSDADFGLSGIILGMLNQFGSQAGIVIGLVLILAVMFGVSFITKPSAKEE"
     gene            complement(9503..9787)
                     /locus_tag="ACL3EZ_001805"
     CDS             complement(9503..9787)
                     /locus_tag="ACL3EZ_001805"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGR0393333.1"
                     /translation="MLKIGTACGSGLGSSFMVQMNIESVLSDLNVSDVEVEHYDLGGA
                     DPNAADIWIVGRDLADSASHLGDVRILNSIIDMDELRELITKLCEEKGLI"
     gene            complement(9791..11821)
                     /locus_tag="ACL3EZ_001806"
     CDS             complement(9791..11821)
                     /locus_tag="ACL3EZ_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000460919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HGR0393334.1"
                     /translation="MFDYRALVILMTLMDHCELSLYELSVKVSLPIKEVKEGIDYLVP
                     YLANKGIVLDKKQGRYSLSNRTKQSLTDIIKSDELVLPKSTRLALIYLYTFCRLDFIS
                     NNHYQDFLKVSKNTTLSDIQSLRKIMLDNDLELGYSRAKGYTLHGSEWNKHRLAFQMV
                     SELLESSIGIWGLDYVLSSWGYSLTYDLINQVVKDYYEKLQLVPIVNQLKVCLFGLVF
                     ILCRYQRDVERVCLSETLVSPVIQDITTILLDTVVDLGIIDTVFSEDDYRYITVLLSS
                     CFEGEVDVAPVYFNQLTEAIISRMEDISLLHFKQREGLRENLRRHLIPAYYRLKFGLP
                     SSNEYVLHVKEHYPDLFELVKDSLMPLMDAIDNPIPDSETAYFVIHFGGYLKKADTLP
                     QKCYKAAIICPNGVSSSLMLKENLLALFPQIEFIGTSKIDDLQVKASSDYDMVFSTIK
                     VETEKPNYLVSVMMTEEQAIQLVELVLKDFPNLEYGDFEIEQILNIVKRYGIITQELE
                     LRLALKNYLYQKNDRKEIVPVLEQLITKETYQVSSQKLGWKEAIRLAAKPLLDQDKIT
                     ENYPEAMIQKVEEFGPFINLGKGVAIPHARPDEGVNEIGMSMLVLEEPIYLLDNPEQE
                     VRLLICIAAIDNESHLKALSHLTTILRDKNHVQTLISSKNYDDIKMIIKQED"
     gene            12012..13019
                     /locus_tag="ACL3EZ_001807"
     CDS             12012..13019
                     /locus_tag="ACL3EZ_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HGR0393335.1"
                     /translation="MTEKLINSKPNGVFALILIELTIVLGIFIFIMGVGSENIFGIII
                     GPLLIVIAGLAHAGLKVVKPQEALVLTLFGNYTGTIKEPGFYFVNPFSVAVNPANHTR
                     LGQSGDVSTKSPFLGAKSSNDNDVNLEIGKKQISLKVMTLSNSRQKINDCLGNPVEIG
                     IAVTWRVVDTAKAVFNVDNYKEYLSLQCDSALRNIVRIYPYDVSPNVDTTGDGQADEG
                     SLRGSSEIVANRIREEIQSRVEDAGLEILEARITYLAYAPEIAAVMLQRQQASAIIDA
                     RKMIVDGAVGMVEMALERLNEGELVELDEERKAAMVSNLLVVLCGNHDAQPIVNTGSL
                     Y"
     gene            13022..13222
                     /locus_tag="ACL3EZ_001808"
     CDS             13022..13222
                     /locus_tag="ACL3EZ_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HGR0393336.1"
                     /translation="MAEAKKKQIPLRLSTKLYAALASWAEDDFRSVNGQIEYLLTECV
                     KQRKKDGKYVSETIDEPFEIDI"
     gene            13374..13556
                     /gene="rpmF"
                     /locus_tag="ACL3EZ_001809"
     CDS             13374..13556
                     /gene="rpmF"
                     /locus_tag="ACL3EZ_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HGR0393337.1"
                     /translation="MAVPARRTSKAKKNKRRTHYKVTAPSVNFDETTGDYSRSHRVSL
                     KGYYKGRKIAKAASAE"
     gene            13572..13721
                     /gene="rpmG"
                     /locus_tag="ACL3EZ_001810"
     CDS             13572..13721
                     /gene="rpmG"
                     /locus_tag="ACL3EZ_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HGR0393338.1"
                     /translation="MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVV
                     FTEVK"
     gene            complement(14200..>14310)
                     /locus_tag="ACL3EZ_001811"
     CDS             complement(14200..>14310)
                     /locus_tag="ACL3EZ_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0393339.1"
                     /translation="FTVSGQWYYTYNSGDLLVNTTTPDGYRVNANGEWVG"
BASE COUNT         4625 a         3017 c         2462 g         4206 t
ORIGIN      
        1 ctttgatttt tattgagtat aaaatcctag tttttcaaag atttctgaga agttttggct
       61 gattgtctca agtgacactt gcacttcttc tcgagtttgg ttgttcttga ccgtcacttg
      121 tccgctttcg acttcgctct ctcctagggt gatgagggtc ttagccacaa agacatcggc
      181 tgacttgaac tgagctttta gtttacggtt gaggtaatca cgctctgctt tgaaaccttg
      241 ttggcgaaga gcctgtacca attccaaggc cttgatattt gccccttcgc ccaagactgc
      301 gatatagaca tctagggcgt tttcgatagg gagggtcaca ccttgctttt caagaatgag
      361 aagcaggcgc tctacaccaa gtccaaaacc aaatccagca gtttcagggc ctccaaaata
      421 agaaaccaaa ccatcgtaac gaccacccgc acagacggtc aggtcattgc cctcaatctc
      481 tgtgataaac tcgaaaatgg tgtggttgta gtagtccaga ccacgcacca tattggtatc
      541 gatgatgtaa tctactccaa gattttccaa catctgacgc acagcatcaa aatgagcttg
      601 gctttcttca tcaagaaagt ccaagataga cggcgcattc tctactgcct ccttgtcttc
      661 tttttcctta gagtccaaga cacgaagagg attttcctcc aagcgacgtt ggctatcctt
      721 agacaaggtc tccttgagcg gtgtcaaata gtcaatcaag gcttggcggt aggctgcacg
      781 gctctcagga tttccaagag tgttgaggtg caatttgaca ccttgaatac cgatttcctt
      841 caaaaaatgg gctgccatag cgattgtttc cacatcggta gctggattgc tagagccaaa
      901 acactcaaca ccaatttggt ggaattggcg caagcgccct gcctgtggac gctcataacg
      961 gaacataggt cccatatagt agaacttgct tggcttttgc acttctgggg cgaagagttt
     1021 attttccaca taggaacgga caacgggcgc agttccttct ggacggaggg taatatgacg
     1081 gtcacccttg tcataaaaat cgtacatttc cttggttacg atatccgttg tatctccgac
     1141 agagcgactg ataacctcgt aatgctcaaa aataggcgtg cgcacttctg catagttata
     1201 gcgcttgaaa atctcacggg caaagccctc aacgtactgc cacttagcag attcagcagg
     1261 taaaatatcc tgcgttcctt ttggtttttg taatttcata gggaatcctc tttaaactta
     1321 atagtcttat tttaccacaa ataaagggat taaaacagta agaaaaaaat taggatttag
     1381 atatcatttt tgagattaag aattgtcaaa aaaatagcta gcaaggaaag accaacaaat
     1441 agcatccaag tcaactgtat attccatacg gctactagtg aaaaacaagc tgttcccaca
     1501 ggtatggata aggtaaacaa tagacctaaa aaattactag tacgagctag aacctctgga
     1561 gctagatttt tcatgagcat ggcactaatc tttggttgaa ctttaccaga cacatacagg
     1621 gtaaagaaga gaaatagcaa accaagcacg acttgattga ataaattagc caaaccaact
     1681 agactaagtc ctacggtcgc ccacatcatc aatctaggca aggactgctt cccaaaataa
     1741 tcattgcccg taaggctact gatgatgatt gctactaaaa cacagaattg attgataaat
     1801 agtgcctctg tataagaaaa attcaagaga gaatggctca aaaagaagat attataaatt
     1861 ccacccaaag cgccacccaa ggaattaata agcaagacag caaagagcat aaaaccaaag
     1921 tttttctgcc cacttttaag aaaaacgaga cgtaaatttc ggtaaattgt taggaactgg
     1981 tctttgatag aaagcttctc attttttaag ttttcaccat cagcagatga cattgacagg
     2041 ctcaatttgc tttttcctaa aaagaggata gtggctgata ctaggaaaaa gcaggcattg
     2101 attcccgcaa cgagagaaaa attgttgacc gacagagcta agagccagac tccgaaagct
     2161 tgaccaccaa tagctgaaat ataggtgatg aactgtgaaa aagaataagc ctccatcaga
     2221 tcatcttcag ctactttttc cttaataaga ggcatgcgca agccacctgc aaaatcactg
     2281 atgacattga tcaaacacag gctagaaaag gcaaagagac tagcttgctg aacaactagg
     2341 gctgctagaa aaaatagaac cgcctgaaac aaaccgctat agaccatcca tttgaccttg
     2401 tccctcgtgt aatctgcccg aatccctaca aaaactgtaa agagggtcgg aagaatcatg
     2461 acaatattcg ccatagcaac agcaaaagat gcttgtgaca aggtcgatgc atagacgata
     2521 aagaccaggt tgaaaatcga agcaccaaaa gcattgaaga agcgtgataa agtcaaaatt
     2581 ctataagcta gatttctaaa caatagtttc atagataatc tcccttcttg ttctaagttc
     2641 tacatcaaga atagctttag tatagcactt atgaatttgc gaaacgattc ttttgaatat
     2701 atgcaacaaa taaaatgagc aaaaaaacga tagaactttt gtaatgacct gagagagggt
     2761 aacagttcta tcgcttcaaa ttttttcttg gtttgcagat actcaacatt cggtcgtatt
     2821 tctatagtat tcggcagatt tattacagcc aagcatctca aaaatacgga cagcatcctc
     2881 catctttttc tggccttcct tgactctacc ttgcttgcta tcaaggagac cttctgccca
     2941 cagataaaca attcggaaat aggtctcatt tcccttgtag aaatgctctt cgataacacg
     3001 tttaaaataa taggcattgg taaattcttc acactcaata ctagctaaaa agccattcaa
     3061 tagtatagta tgaaaaaggt ttcgattgcc agacatttcc attagaaaat cggatttacg
     3121 taccatttct cgtacatatc tagtaaaaag agaaacagat aaaaatggag aactgactga
     3181 aaataaattg agttcataga ttccccagat ctcggtagaa aacaaataat catgaaggac
     3241 ttttccttcc tctgctgtta agtctaccct ttcatctatg ctcttcatat aagacttgat
     3301 aataatggca tttagaatat gtttctgttt gttgtgagaa tgggcatgct tttgatactc
     3361 cctgcgatat aagtcctcaa gaggtgctat attctttggt tccaagacat ctgtaatttc
     3421 ttttctcaac tcagaatctg tatcatactg gaaacctctc gccagaaaga ggatctcctc
     3481 cacactggca gatatatttt ccagagcaaa tagaaacttt tccaccgaaa gctcactctg
     3541 acctgtttca aaacgggaca acatagacgg cgaaaattgt cctccggttg cttgtctcag
     3601 tgagatattt cttgattctc gtaattgtct aaagactttt ccaatctgct ccatagactt
     3661 ccccttgatt ccgtattttc ttcattttat catatttttc agaaaattca tcaaaaactt
     3721 gccaaattgt cagaattatg agaaaataga ggatatttat cacgtggagg gactgctatg
     3781 agagacgata tcaaaatcaa tgaccgtgct ttggccttgc aagaccaaat catcgaaaaa
     3841 ctagagaaag tttttgatac agatgtggaa ttggatgttt acaatctagg tctgatttat
     3901 gaaatcaatc tggatgaaac ggggctctgc aagattgtca tgaccttcac cgatactgcc
     3961 tgtgattgcg ccgaaagcct gcctattgaa atcgtggcag gtctgaaaca aatcgagggt
     4021 atcaaagata tcaaggttga agttacctgg tcgcctgctt ggaaaatcac acgaatcagt
     4081 cgctatggcc gtattgccct tggactacca cctcgttaag caggccaatc acttttaaag
     4141 atgaaaaaag caagccaaaa atggcttgct ttttgatact caatgaaaat caaagggcaa
     4201 actagaaaac tagccgcagg ttgctcaaaa cactgttttg aagttatgga tagaactgac
     4261 gaagtcagct caaaatactg ttttgaagtt atggatagaa ctgacgaagt cagctcaaaa
     4321 tactgttttg aggttgtgga tagaactgac gaagtcagta accataccta cggcaaggcg
     4381 acgttgacgt gatttgaaga gattttcgag tatgagttta ttttttacct gacttgtcca
     4441 tattccagaa gtctgtcacg gctccgcgtg aagcagatga tacgatgtgg gcatatttac
     4501 cgaggacacc acggctgtaa agtggtggca aggttgtttc tgccttgcgt ttttcaagtt
     4561 cttcttcgga tacggccatg gaaatttctt tggtatcttg gtcaaccgta acgatatcgc
     4621 cggtacggag ataggcaatt ggtccaccat cctgagcttc aggagcgata tgtccaacaa
     4681 ccagaccata agtaccacca gagaaacgtc cgtccgtcaa gagggccacc ttatctccct
     4741 gacctttacc aacaatcatt gaagaaagtg acagcatctc aggcatacca ggaccacctt
     4801 taggtccaac aaaacgaaca acgactacat cgccatcaac gatttcatct gtcagaacgg
     4861 cctgaatcgc atcttcttct gagtcaaaga ccttagctgg cccaacgtga cgacgcactt
     4921 taacacctga taccttggca actgcaccgt caggagcaag gttcccgttc aagatgataa
     4981 gcggaccatc cgcacgtttt ggattttcaa gtggcatgat aactttttgg cctggagtca
     5041 agtctgcaaa gtcagccaag ttttcagcta cagtcttacc agtacatgtg atgcgatctc
     5101 cgtgaaggaa accatttgcc aacaagtact tcataaccgc agggacacca ccgacttcgt
     5161 agaggtcttg gaagacatac tgaccagatg gtttcaagtc ggccaagtga ggcacacgtt
     5221 cttgaatcgt attgaagtcc tcaagtgaca agtcaacatt tgcggcatgg gcaatggcga
     5281 gcaagtgaag agtggcgttt gtagaaccac cgagagccat cgttacagta atagcatctt
     5341 caaaggcttc acgagtcaag atatctgatg gtttgagacc aagttccaac atcttaacaa
     5401 cagcacgtcc tgctgcttcg atatcttctt tcttatcagc tgattcagct gggtgagagg
     5461 atgaccctgg caaactcatc cctagaactt cgatagcagt tgccatggta ttagcagtat
     5521 acataccacc acagccacca gggccagggc aggcattaca ttcaagacgt ttcacgtcct
     5581 cagctgtcat gtcaccgtgg ttccattttc cgataccttc aaagacagaa accaagtcga
     5641 tatctttacc atcaagattt cccggtgcaa tagttccacc ataggcgaaa atagctggga
     5701 tatccatatt agcaatagca atcatagatc caggcatgtt cttgtcacag ccaccgatag
     5761 cgacaaaggc atccacgttg tgaccactca tagccgcctc gatggagtcc gcgatgatgt
     5821 cacgagatgt tagagagaaa cgcataccag gcgttcccat agcgatcccg tctgctacgg
     5881 taatggttcc aaactgtaca ggccaagcgc ctgcagattt gacaccttct ttagccagtt
     5941 tcccgaaatc atgcaagtga atgttacatg gtgtattttc cgcccaagtc gaaatcactc
     6001 ccacaatcgg tgtttcaaag tccttatctg tcataccagt cgcacgaagc atagcacggt
     6061 taggtgattt aaccatgctg tcataaatgc tactgcggtg acgtttatct aattcagtca
     6121 tcttatccct cccatttcag tttttactat tatagcacaa ttttcgcatg aagaacagaa
     6181 taaaaatctt gaattttcag aaaattctat acacatgtga aatatttaaa attaaaaaca
     6241 acaaagcgga ttagtgcact ttctgatgac cagaatatgc tttttaatcc gctttcttta
     6301 aataacgtac tgtaattttt acagaaattc tttcagataa gtgtatttaa catctatctt
     6361 gcattataaa tttctagaac cttctctttt atattcgatt cactcaaacc atactcatta
     6421 agaagataat ccattttccc tacttgaccg aatctttctt gaacacccat ccgatgaatt
     6481 tttgtcattc catcatcaga gaataattca cataaagaac tgccaattcc acctatctga
     6541 ttgtggtttt ctacagtaaa tatagttttt ccacttaaca ttgtttttat ctgttctggt
     6601 atcggtttga ttctaaataa atctatcaca cttactgaat aacctaattt agacagttca
     6661 tctgcaactc gaatacttgg agcaaccatt ataccagaag caacgattac aagatcttca
     6721 ccatgcctta actcaatgta gcctttagaa aaatcttctc caccttgata cacaggaact
     6781 ggagcttttc taattgttcg aatatatttt agtcctttta agtctaatgt ctggttcaat
     6841 atttcacgaa attggatatc atcagttgct tcaaaaatga tcgatttagg aattaaacgt
     6901 aacaatccaa tttcttcaaa tggcatatgt gtcccaccat tcatttctgc agttactcct
     6961 gcatctgatc caatcacagt ggcatccaat tgtgcgtatc caagagaaat aaataattga
     7021 tcaaatactc ttcgtgaagc aaaaggacca aatgtatgaa gataaggtct aaacccctga
     7081 atagacaagc ctgctgcaag gccgaccatt tctgcttcca taatcccaac attcacataa
     7141 cggtctccaa aatccttttc aagattatta gtagccatcg aacttgacaa atcggcttct
     7201 aagactacta tatcagaata actttgatta gcctctaaaa ggaagtctct atatacatgc
     7261 cgtaattctt tcgtgcttct catcattctg tttcctccaa ttcctgactt aatctttcta
     7321 caactgaagt taacatttgt ctctcctcta cagtagggcg aagatgatgg ttggatttca
     7381 tttcttccag ctcttgaacc ccttgacctt taatagtatc taatacaatg cacttaggtg
     7441 atgaattatt tgactgtttt aattggacaa tcccttcata aatttctcta atatctgaac
     7501 ccttgaccct aatggattca aatccaaatg ctgaaaattt ttctacgaaa tcacctggat
     7561 tacaaatatc ctttgtaaaa ccatctaatt gttttttgtt atcatcaaca aatacaatta
     7621 agttggataa ctgttgatga gaagcaaact gtatagcctc ccaacattgt ccctcattta
     7681 actcaccatc tccaacaata gcataagtat aaaagggact ctttcttatt ctctgaccat
     7741 atgcaagtcc agttgcaaca ctaattcctt gtcctaaaga gcccgttgtc atatctatgc
     7801 ctggcgttag atttctatca ggatgagacg gtaatttggt tccatttgta tttaaagaat
     7861 ataagaattc tttgtcaaag aaaccattca aatagagtgt actgtataga gctggtcctc
     7921 cgtgaccttt tgataatatg aaataatctc tatctcgtgc tgcaaatatt tctggagtca
     7981 ttggcattat ttcaccataa agcactgcta aaacttctac gatagacaga cttcctccgt
     8041 aatgtccgaa tccaagatga ttcaatgttc taagagtatt taatcggatg ttagtcgcaa
     8101 attttcttaa ctcatcttcc ctatttttac ttaaaatcat cccttattcc tcctttgcag
     8161 atggctttgt aataaaggat actccaaaca taactgctag aataagaaca agaccaatca
     8221 caatgcctgc ttgtgagcca aattgattta acattcctaa aataattcct gatagaccaa
     8281 aatctgcatc tgagaaagtt gatccttgga aaccaagtcc tcccaaaact ggcattaaaa
     8341 agactggaag aaaactgatt aaaatacctt gtaaaaatgc tccaatagtg gctccacgaa
     8401 caccaccaga tgcattccca atgacacctg cagtcgctcc acagaagaaa tgaggcacaa
     8461 cacctggtaa gataacaacc gttcctgaag caatcataat tgccatactt actaaaccac
     8521 caacaaaact agagataaat ccaattagaa ctgcattggg tgcataagta taaacaatcg
     8581 gacaatccaa agcaggtttt gaattaggta caagacgctc tgaaatacct ttaaaggctg
     8641 gaacaatttc gcccaaaata aggcgaacac ctgctaaaat aacaaatacc cctgctgcaa
     8701 attgacctgc taattgtaaa gcataaacta gaccacttgt accactactg atttcttttt
     8761 ctatatattc tgaccctgca aagatagcta caataatgta aataactgcc atggataaag
     8821 tgatactaac agtactatca cgtaaaaaag ctaaactctt tggaaattta atgtcctctg
     8881 ttgattttga tttgtcaccg ataaggctac cagtaaaacc actcaaccaa tatcccaaag
     8941 aactgaaatg acctaaagcc accttgtcat ttccagttaa ttgaaccata tatttttgaa
     9001 caaatgctgg ggaaatactc ataataatac cgagtgctaa tcctcctagt aagataagag
     9061 gcaagctagt aaagccagca actgataaaa tgaccgcaat catacatgcc atatatagag
     9121 tgtggtgccc tgttaaaaaa atatatttaa atcgagtaaa acgagcgatt aagatattga
     9181 acaccatgcc tgcaaacata atcagtgcag tagctgagcc atatgttgtt aaagctacag
     9241 ctacaattgc ttcattattc ggcacaacgc cagataaatg aaaagcatgc tcaaacatgg
     9301 taccaaatgg atttaaagaa ttttgtacaa ttcctgcacc accagataca actaagaaac
     9361 caacaaaggt cttaattcca cctttaataa tatcaggtaa tttcttcttc tgaagaacta
     9421 atcctaaaat tgcaattaaa gctactaaaa tagctggtgt actaacaata tccaatatga
     9481 acttcatcat aacgctagcc tcctatataa gtcctttttc ttcacaaagt ttagtaatta
     9541 attctcgtag ttcatccata tcaataatac tatttaagat acgaacatct ccaagatgac
     9601 tagctgaatc agctagatca cgaccaacaa tccaaatatc agctgcattt ggatctgctc
     9661 cacctaaatc ataatgttca acttctacat ccgaaacatt caaatcactc aatacagatt
     9721 caatattcat ctgtaccata aaacttgaac ctaatcctga accacaagct gtaccaattt
     9781 ttaacattat ctaatcctcc tgtttaatta tcattttaat gtcatcatag ttttttgatg
     9841 atattaaagt ttgaacatga tttttatctc ttaaaattgt tgttaaatgt gacaaagcct
     9901 ttaaatgact ctcattatca atggctgcaa tacaaatcaa caatcttacc tcttgttctg
     9961 gattatccaa taaataaatc ggttcttcca aaactaacat tgacattcct atttcattca
    10021 caccttcatc tggccgagcg tgaggaattg ctactccctt ccctaaatta ataaaaggcc
    10081 caaactcttc tactttttga atcattgcct cagggtagtt ctcagttatc ttatcttgat
    10141 ccaaaagcgg tttagctgct aaacgaatcg cctccttcca tcctaatttt tgcgaactaa
    10201 cctgataggt ttctttggta atgagttgtt ctagcactgg tacaatttcc tttctatcat
    10261 ttttttggta aagataattc tttaacgcca atcttaattc caattcttgt gtaataattc
    10321 catatctttt gacaatattc aggatttgtt caatctcaaa atccccatac tctaaattcg
    10381 gaaaatcttt taacactagt tctactagtt gtattgcttg ctcttcagtc atcataaccg
    10441 aaactagata atttggcttt tctgtctcca cctttatggt agaaaaaacc atatcatagt
    10501 cactactagc tttcacctgt aaatcatcaa tctttgaggt tcctataaac tcaatttgag
    10561 gaaataatgc taatagattc tcttttaaca tcaatgaaga actaacacca ttaggacaaa
    10621 tgattgctgc tttatagcat ttttgaggca aagtatctgc tttctttaaa taacctccga
    10681 aatggataac aaaatatgct gtttcactat caggtatggg attgtcaata gcgtccatca
    10741 agggcatcaa agaatctttg actaattcaa ataaatcagg ataatgttct ttaacatgca
    10801 atacatattc atttgaacta ggtaggccga actttaatct atagtaagcc ggtataaggt
    10861 ggcggcgaag attttctctc aatccttccc tttgtttaaa atgtaacaaa gaaatatctt
    10921 ccattctact tataatagcc tctgttaatt gattaaagta aaccggagca acatctactt
    10981 caccttcaaa gcaacttgat aataaaacgg tgatatagcg ataatcatcc tcagaaaaca
    11041 ccgtatctat aattcccaaa tcaaccactg tatccaataa aatagtcgtt atatcttgaa
    11101 taacaggaga tactaatgtc tctgaaagac atactctttc aacatccctt tgatacctac
    11161 acagaatgaa tactaaaccg aaaaggcaaa cttttaattg attaacaata ggtactagct
    11221 gtagcttctc ataataatct ttaactacct gatttatcaa atcataagtt aatgaatacc
    11281 cccaactgga taaaacataa tccaaacccc aaatccctat ggaggattcc agcaactcac
    11341 taaccatttg aaaagctaag cggtgcttat tccactctga accgtgtaaa gtataacctt
    11401 ttgctctact gtaccctagc tccaaatcat tatctaacat aatctttctt aatgattgaa
    11461 tatcagataa ggttgtattc ttacttactt tcaaaaagtc ttggtaatga ttattcgata
    11521 taaaatctaa tcggcaaaaa gtgtaaagat agattaaagc taagcgagtc gactttggta
    11581 aaaccaattc atccgactta ataatatctg tcaaagactg cttcgtacga tttgataaac
    11641 tatagcgacc ttgtttttta tccagcacta tccctttatt agctagataa ggcactaaat
    11701 aatctattcc ttctttgact tcctttatag gtaagctcac cttaacagat aattcatata
    11761 atgatagctc acaatgatcc atcaaagtca tcaaaataac tagtgctcta taatcaaaca
    11821 tttctcttcc tttctaacta caattatagt gtaaaaatta taagaataaa agagtatttg
    11881 agcacaatat aatctcacct tttaaaagaa attattgggc tgaaactttt tagtgattat
    11941 tttcaacttt ctattgactt ttaaaaacaa agtgatatca tttagatatc aaataatagg
    12001 aggtcattct tatgactgaa aaactcatca attcaaaacc aaatggtgta ttcgcattga
    12061 ttctcattga attgacaatc gtacttggta tctttatatt tataatgggt gttggttcgg
    12121 aaaacatttt tggaattatt atcggacctt tactaatcgt aattgcaggt ctagctcatg
    12181 ctggtttaaa agttgtcaaa cctcaggaag ctctggttct gacactcttt ggtaattata
    12241 caggtaccat caaagaacct ggtttttact ttgtcaatcc cttcagcgta gcagtcaacc
    12301 ctgcaaacca cactcgactt ggacaaagtg gtgatgttag cacaaaatct ccttttttag
    12361 gagctaaatc atcaaatgac aatgatgtaa atcttgaaat tggcaagaaa cagatttccc
    12421 tcaaagtcat gaccttgagc aattctcgtc aaaaaatcaa tgattgctta ggaaaccctg
    12481 tagaaatcgg tatcgcggta acttggagag ttgtcgatac cgctaaggca gtcttcaacg
    12541 ttgataacta caaagaatat ctttcattgc aatgtgatag cgccctccgt aatattgtcc
    12601 gcatctatcc ttacgatgtg tctcctaatg tggatactac gggtgacggg caagcagatg
    12661 aaggtagtct ccgtggctct agcgaaattg ttgctaaccg tattcgtgaa gaaatccaaa
    12721 gtcgtgttga ggatgctggc ttggaaatcc ttgaagcacg tatcacttac ctagcttatg
    12781 ctccagaaat tgctgccgtt atgcttcaac gccaacaagc atctgccatt attgatgcac
    12841 gtaagatgat tgtagatggt gctgtaggaa tggttgaaat ggcactagaa cggctcaatg
    12901 aaggggaatt ggtagaactt gacgaagaac gaaaagctgc catggtttca aatctccttg
    12961 tcgttctttg tggcaatcat gatgcacaac caattgtcaa cacaggaagt ctttactaaa
    13021 gatggctgaa gctaaaaaaa agcagatccc ccttcgactc tcaacaaagt tatacgctgc
    13081 actcgcatca tgggcagaag acgactttcg ttcagtcaat gggcaaatag aatatctcct
    13141 cacagagtgt gtcaagcaac ggaaaaaaga cggaaaatac gtatcagaaa ccattgacga
    13201 accatttgag attgatattt aacaccttct cctgtctgcc gtgtcggata ggagaatttt
    13261 ttcatctttt tttgtcaagt aactttactt tacaaaaaaa atgtgttatc ctagtatggt
    13321 tgatgaaaat cagtagattg aatcgaatat aaatacctaa aggagaaatc aaaatggcag
    13381 tacctgcacg tcgcacttca aaagcgaaga aaaacaaacg tcgtacacac tacaaagtaa
    13441 cagctccatc tgtaaacttt gacgaaacta ctggagatta ctcacgttct caccgtgtat
    13501 cacttaaagg atactacaaa ggacgtaaaa tcgctaaagc tgcatcagct gaataataga
    13561 agggagatac tatgcgcgta aatattacac ttgaacacaa agaatctggt gaacgcttgt
    13621 accttacttc taaaaacaaa cgtaacactc cagaccgcct tcaattgaag aaatactcac
    13681 caaaacttcg caaacacgtt gtgtttacag aagtgaagta agcattcaat acgaatcaat
    13741 acagaagaaa aacgcttgat cagcgttttt tctttttgtt aatttcacta tattgcaagg
    13801 gaaatcattc gaatgactac attattgaaa taagaatacg gattcggaca attaaaagca
    13861 agaggaactc aaatgtaagt tggggttcct tttttgtata tttttcaaat aacgcctcta
    13921 cactatttgt agcaaattca ccaactacag ttgtatctta gttaaaataa gttagaatat
    13981 gtaagtgagt accagatata ccaagacatc gtcaccatct aaggtatatt caaaatacaa
    14041 aagttgacca actagatttc tgaatatcct tatatatcca ttcttaaaat tggtttaaat
    14101 agcgtagtct tttaaactag ttttgagaat ccaaaaaatc ttcctacata tgtaagaaga
    14161 ttttttagtt cagaatgatt agatttagct aatggatacc tatcctaccc actcaccgtt
    14221 agcattgact cgatagccat cgggtgtagt cgtgtttact aataaatctc ctgaattata
    14281 ggtatagtac cattgaccag aaactgtaaa
//
LOCUS       DBEJHE010000042        13709 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC4 isolate 671759
            SAMN38261586-rid24793303.denovo.42, whole genome shotgun sequence.
ACCESSION   DBEJHE010000042 DBEJHE010000000
VERSION     DBEJHE010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261586
            Sequence Read Archive: SRR26833752
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 13709)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13709)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576136.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576136.1
            Genome Coverage       :: 109x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 19:48:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,067
            CDSs (total)                      :: 2,029
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 131
            CDSs (without protein)            :: 131
            Pseudo Genes (ambiguous residues) :: 0 of 131
            Pseudo Genes (frameshifted)       :: 64 of 131
            Pseudo Genes (incomplete)         :: 59 of 131
            Pseudo Genes (internal stop)      :: 46 of 131
            Pseudo Genes (multiple problems)  :: 32 of 131
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13709
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261586-rid24793303.denovo.42"
                     /strain="GPSC4"
                     /isolate="671759"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(779..1648)
                     /gene="gla"
                     /locus_tag="ACL3EZ_001812"
     CDS             complement(779..1648)
                     /gene="gla"
                     /locus_tag="ACL3EZ_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000348128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0006071 - glycerol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aquaglyceroporin Gla"
                     /protein_id="HGR0393340.1"
                     /translation="MDFTWALKYATEFLGTAILIILGNGAVANVELKGTKGHQSGWIV
                     IAVGYGMGVMIPALMFGNVSGNHINPAFTLGLAVSGLFPWAQVVPYIIAQVLGAIFGQ
                     ALVVATYRPFYLKTENPNNILGTFSTISSIDHGTKESRYAATVNGLINEFVGSFVLFF
                     AALGLTKNFFGAEVLQFMKQKAIEAGQTVDFSDLAIKAQVAPHTASGLSVAHLALGFL
                     VMALVTSLGGPTGPALNPARDLGPRLLHAFLPKSVLGEHKGDSKWWYSWVPVVAPIVA
                     AIAAVAVFKFLYL"
     gene            complement(1872..2549)
                     /locus_tag="ACL3EZ_001813"
     CDS             complement(1872..2549)
                     /locus_tag="ACL3EZ_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HGR0393341.1"
                     /translation="MVPKTATSTETKTITRIIHYVDKVTNQNVKEDVVQPVTLSRTKI
                     ENKVTGVVTYGEWTTGNWDEVVSGKIDKYKDPDIPTVESQEVTSDSSDKEITVRYDRL
                     STPDKPTPEKPEIPSPQEPGTPGEPTPEKPIPQPNPEHPSVPTPNPELPNQETPIPEP
                     TPEPGTPKTETPVNPDPEVPTYETGKREELPNTGTEANATLASAGIMTLLAGLGLGFF
                     KKKEDEK"
     gene            complement(2507..3613)
                     /locus_tag="ACL3EZ_001814"
     CDS             complement(2507..3613)
                     /locus_tag="ACL3EZ_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HGR0393342.1"
                     /translation="MNIILIAKLLRENTNTKANALNNGWARSGSEEFKKFSHFVGVDK
                     GIVRTNVLTGKKLSDKIRKEVGSGDSKLGKGGYFSTGDVLLGKDVVSYTVQVFSENNE
                     RVGVNTQSHRVQYNLPILADFSVIQDTVEPSRTVVEKIIPKLNIPEEEKGKITEEIKK
                     KKKTSELAELISENVKVRYVDEQGRLLSLKNDTGIGEKESDGTYITNKKQLIGTSYNV
                     TDKKLSSMTTTDGKYYTFKEADTNSASLTGNIVSEGRTVTLVYRESEAPTTATVTANY
                     YKEGSQEKLAESVIKADLAIGSEYTTESKTIEGKTTTEDKEDRVITRKTTYTLVATPA
                     NAYQKTVQQLTITTVRMLRKQWFPKQQPLLRRRL"
     gene            complement(3724..3978)
                     /locus_tag="ACL3EZ_001815"
     CDS             complement(3724..3978)
                     /locus_tag="ACL3EZ_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0393343.1"
                     /translation="MLNVDQDFMSISKSNKSGSDWKKTFTVRITNRLANDLNNVLKQA
                     DKDTPNTPTWLNSAASKAKDDDRVYKLLKTLIPGENYLSC"
     gene            complement(3972..4214)
                     /locus_tag="ACL3EZ_001816"
     CDS             complement(3972..4214)
                     /locus_tag="ACL3EZ_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000284543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0393344.1"
                     /translation="MVQNEDLYKKGLNVELAHQQIKGFFEAEFKNRINGVLNTKIKNS
                     TLNRVNKKTIHQSNKNSMINLKQKQRKMLKNKAILC"
     gene            complement(4318..5162)
                     /locus_tag="ACL3EZ_001817"
                     /pseudo
     CDS             complement(4318..5162)
                     /locus_tag="ACL3EZ_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078372828.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            5396..7114
                     /locus_tag="ACL3EZ_001818"
     CDS             5396..7114
                     /locus_tag="ACL3EZ_001818"
                     /EC_number="5.4.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016868 - intramolecular
                     phosphotransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HGR0393345.1"
                     /translation="MSYQENYQKWVDFVELPDYLRQDLENMDEKTKEDAFYTNLEFGT
                     AGMRGLVGAGTNRINIYVVRQATEGLARLIESKGGNEKERGVAIAYDSRHFSPEFAFE
                     SAAVLAKHGIKSYVFESLRPTPELSFAVRHLNCFAGIMVTASHNPAPFNGYKVYGEDG
                     GQMPPHDADALTTYIRAIENPFAVEVADVETEKASGLIEVIGEAVDIEYLKEVKDINI
                     NPALIEEFGKDMKIVYTPLHGTGEMLARRALAQAGFDSVQVVEAQATADPDFSTVTSP
                     NPESQAAFALAEELGRQVGADVLVATDPDADRVGVEVLQKDGSYLNLSGNQIGAIMAK
                     YILEAHKNAGTLPENAALCKSIVSTDLVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNHTYMMGFEESFGYLIKPFVRDKDAIQAVLVVAELAAYYRSRGLTLADGIEEIYKE
                     YGYYAEKTISVTLSGVDGAEQIKAIMAKFRNNAPTEWNATAITVVEDFKAQTATVADG
                     TVTNLTTPPSDVLKYTLADGSWIAVRPSGTEPKIKFYIAVVGETNEESQAKIANIEAE
                     INAFVK"
     gene            7225..7572
                     /locus_tag="ACL3EZ_001819"
     CDS             7225..7572
                     /locus_tag="ACL3EZ_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HGR0393346.1"
                     /translation="MEQFLDNIKDLEVTTVVRAQEALDKKETATFFIGRKTCPYCRKF
                     ADTLSGVVAETKAHIYFINSEEPSQLNDLQAFRSRYGIPTVPGFVHITDGQINVRCDS
                     SMSAQEIKDFAGL"
     gene            complement(7850..8686)
                     /locus_tag="ACL3EZ_001820"
     CDS             complement(7850..8686)
                     /locus_tag="ACL3EZ_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HGR0393347.1"
                     /translation="MKKWMLVLVSLMTALFLVACGKNSSETSGDNWSKYQSNKSITIG
                     FDSTFVPMGFAQKDGSYAGFDIDLATAVFEKYGITVNWQPIDWDLKEAELTKGTIDLI
                     WNGYSATDERREKVAFSNSYMKNEQVLVTKKSSGITTAKDMTGKTLGAQAGSSGYADF
                     EANPEILKNIVANKEANQYQTFNEALIDLKNDRIDGLLIDRVYANYYLEAEGVLNDYN
                     VFTVGLETEAFAVGARKEDTTLVKKINEAFSSLYKDGKFQEISQKWFGEDVATKEVKE
                     GQ"
     gene            complement(8699..9328)
                     /locus_tag="ACL3EZ_001821"
     CDS             complement(8699..9328)
                     /locus_tag="ACL3EZ_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HGR0393348.1"
                     /translation="MLELRNINKVFGDKQILSDFSLSIPEKQILAIVGPSGGGKTTLL
                     RMLAGLETIDSGQIFYNGQPLELDELQKRNLLGFVFQDFQLFPHLSVLENLTLSPVKT
                     MGMKQEEAEKKASELLEQLGLGGHAEAYPFSLSGGQKQRVALARAMMIDPEIIGYDEP
                     TSALDPELRLEVEKLILQNRELGMTQIVVTHDLQFAENIADVLLKVEPK"
     gene            complement(9338..9979)
                     /locus_tag="ACL3EZ_001822"
     CDS             complement(9338..9979)
                     /locus_tag="ACL3EZ_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HGR0393349.1"
                     /translation="MSYLFEILPSLLNGASTTVQVFALVLLFSIPLGVLIAFALQVHW
                     KPLHYLINIYIWVMRGTPLLLQLIFIYYVLPSIGIRLDRLPAAIIAFVLNYAAYFAEI
                     FRGGIDTIPRGQYEAAKVLKFSPFDRVRYIILPQVTKIVLPSVFNEVMSLVKDTSLVY
                     ALGISDLILASRTAANRDASLVPMFLAGAIYLILIGIVTIISKKVEKKYSYYR"
     gene            complement(10125..11354)
                     /locus_tag="ACL3EZ_001823"
     CDS             complement(10125..11354)
                     /locus_tag="ACL3EZ_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HGR0393350.1"
                     /translation="MNNSQQMLQALEEQDLTKAEHYFAKALENDSSNLLYELATYLEG
                     IGFYPQAKEIYLKIVEDFPEVHLNLAAIASEDGQIEEAFTYLEEIQADSDWYVSSLVL
                     KADLYQLEGLTDVAREKLLEALTYSEDSLLILGLAELDSELENYQAAIQAYAQLDNRS
                     IYEQTGISTYQRIGFAYAQLGKFETATEFLEKALELEYDDLTAFELASLYFDQEEYQK
                     ATLYFKQLDTISPDFEGYEYGYSQALHKEHQVQEALRIAKQGLEKNPFETRLLLAASQ
                     FSYELHDASGAENYLLTAKEDAEDTEEILLRLATIYLEQERYEDILDLQSEEPENLLT
                     KWMIARSYQEMDDLDTAYEHYQELTGDLKDNPEFLEHYIYLLRELGHFEEAKVHAHTY
                     LKLVPDDVQMQELFERL"
     gene            complement(11344..12510)
                     /locus_tag="ACL3EZ_001824"
     CDS             complement(11344..12510)
                     /locus_tag="ACL3EZ_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HGR0393351.1"
                     /translation="MEQKEKHFSLSWFFKWFLDNKAITVFLVTLLLGLNLFILSKISF
                     LFSPVLDFLAVVMLPVILSGLLYYLLNPIVDWMEKHKVNRVIAITIVFVIIALFIIWG
                     LAVAIPNLQRQVLTFARNVPVYLEDIDRIVNGLVAQHLPDDFRPQLEQVLTNFSSQAT
                     VLASKVSSQAVNWVSAFISGASQVIVALIIVPFMLFYLLRDGKGLRNYLTQFIPRKLK
                     EPVGQVLSDVNQQLSNYVRGQVTVAIIVAVMFIIFFKIIGLRYAVTLGVTAGILNLVP
                     YLGSFLAMLPALVLGLIAGPVMLLKVVIVFIVEQTIEGRFVSPLILGSQLNIHPINVL
                     FVLLTSGSMFGIWGVLLGIPVYASAKVVISAIFEWYKVVSGLYELEGEEVKSEQ"
     gene            12654..13667
                     /locus_tag="ACL3EZ_001825"
     CDS             12654..13667
                     /locus_tag="ACL3EZ_001825"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052689 - carboxylic ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HGR0393352.1"
                     /translation="MKETVYFGTYTRRTSQGIYKADFDTETGQLSNLELFAAEPSPTY
                     LAFDQHQHLYTVGSQDDKGGIAAYQTDGTVLNHVVEKGAPHCYVAVDEKRDLVYAANY
                     HKGQVLVYKRQEDGSLLLSDMDQHSGQGPHENQASPHVHYTDLTPDHYLVTCDLGTDQ
                     VITYDLDQEGKLSKLYTYHSKPGAGSRHIIFHNHYKIAYLICELNSTIEVLIYDGVGE
                     FERMQVISTLPEAYEGFNGTAAIHLSKDGKYLYASNRGHDSIAVYTILADGSLELLEI
                     VPTHGQTPRDFDLTPDQKFLIVVHQDSDNATVFKRNCDNGRLAELSNDFHVPEAVCIR
                     FAP"
BASE COUNT         4143 a         2933 c         2440 g         4193 t
ORIGIN      
        1 taaaaattta actaattaat agaaagtact aaatagactt atccttcaag gagttttcag
       61 cattatccat ccactcactt gctgaaaatg taaacagtct ctggtttata tagtaaaatg
      121 aaacaagaat agagcaaatc gatcaggaca gtcaaatcga tttctaacaa tgttttagaa
      181 gtagatgtgt actattctag tttcaatcta ctatacaacc tcaaaactgt gttttgaaca
      241 acctgcggct agcttcttag tttgcccttt gattttcatt gagtataaaa ttgcagataa
      301 aacgataaca atcataggac tcagcagagt caatgtaggt cgaagaatag cccccctaat
      361 cgcttatttt atagcaaaat gaaatagaaa ctgaacattt tgttgaggaa ggtaaatcaa
      421 ttcctcacaa tgtttgagaa agaagggagg actattccaa cttcaaccca ctataaagca
      481 gacttacaag atagggaacc catctccgat aatatatagt agaatgaaaa ctgcacaatt
      541 tgattggaga attcaaacca atttctcaca atgttttaga aacaagggtc tattatttca
      601 actgcaacct actatagtcc attgaagctg gaatagccca ctgagacttc taaaccactg
      661 ctggagagga gtttgtttag agtttctttc atttccctaa aaaatcaaaa agagagaacc
      721 agtctgatcc tctcttactt atagatggtg ctcactcaaa tgttaaagga gctatttctt
      781 agagataaag gaatttgaat acagctactg ccgcaattgc tgctacgata ggtgctacta
      841 ctggtaccca agaataccac cattttgaat cgcctttatg ctcaccaaga actgattttg
      901 gaaggaaagc atgaaggaga cgtggtccca agtcacgggc tgggttcaag gcaggtcctg
      961 taggtcctcc aagtgatgtt accaaagcca taacgaggaa tccaagtgcc aagtgagcca
     1021 cagaaagtcc tgaagcagtg tgtggagcca cctgtgcttt aatagccaag tcagaaaaat
     1081 caactgtttg tcctgcttct attgcctttt gtttcatgaa ttgaagcact tcagcaccaa
     1141 agaagttttt agtcaaacca agagctgcaa agaacaaaac aaatgaacca acaaactcat
     1201 taatcaaacc attgacagtt gctgcatagc gactttcttt tgtaccatgg tcaatacttg
     1261 aaatagttga gaaagttccc aagatgttat ttgggttttc agttttcaag tagaatggac
     1321 ggtatgttgc cacaactaag gcttggccaa agatagctcc caagacttgc gcgataatat
     1381 aaggtaccac ttgtgcccaa gggaaaagac cgctaactgc aagccctaga gtgaaagcag
     1441 ggttgatgtg attcccagat acgttaccaa acatcaaggc tgggatcata acccccatac
     1501 cataaccaac agcgatgacg atccagccac tttggtgacc tttcgtacct ttaagttcaa
     1561 cgttggcaac tgcaccattc ccaagaatga tcaaaatggc agttcccaaa aattcagtgg
     1621 catacttcag tgcccatgtg aaatccattt gctagattct ccttaaaatt ttttagatat
     1681 tccttatttt atcaattttt accctattta gcaactgatt tctggaaata tttttaaaaa
     1741 aataggattc atagtttccc agttcaacgg acttgtaagc gtttttattc ttcacgaaag
     1801 acctcgttct caaaaccagg aaaaaagccc acatctgtga gcttttcctg gttcctagat
     1861 tctaaaatct attatttttc atcttctttt ttcttgaaga atcctaatcc tagaccagct
     1921 aacaaggtca tgataccagc actagccaag gtagcattag cttctgtacc tgtgtttggc
     1981 aattcctctc tcttacctgt ctcataagtc ggaacttctg ggtctggatt cactggagtt
     2041 tcagtttttg gagtacctgg ttctggagtt ggctctggta ttggagtctc ttgatttggt
     2101 agttctgggt ttggtgtcgg aacacttgga tgctctggat ttggttgtgg gattggtttt
     2161 tctggagtcg gttcacctgg agtacctggt tcctgaggac ttggaatttc tggtttttct
     2221 ggagttggtt tatctggtgt tgataaacgg tcatacctta ccgttatttc tttatcacta
     2281 gagtctgacg taacttcttg tgattcaact gttggaatat ctggatcttt gtacttgtca
     2341 atcttaccag atacaacctc gtcccagttt cctgttgtcc attcaccgta ggttacaact
     2401 cccgtgacct tgttctcaat ttttgtacgg cttaaggtta caggttgaac aacatcttct
     2461 tttacatttt ggttcgtaac tttatcaacg taatgaatga tacgcgttat agtcttcgtc
     2521 tcagtagagg ttgctgtttt gggaaccact gtttcctcaa cattctcacg gtagtaatag
     2581 tcaactgttg caccgtcttc tggtacgcat ttgcaggagt tgctaccaag gtgtatgttg
     2641 ttttccttgt gataactcgg tcttctttgt cctcagttgt tgttttccct tcaatagttt
     2701 ttgattctgt ggtatactca gaacctatcg ctaaatcagc ttttataaca gactctgcca
     2761 acttctcttg gctaccttct ttatagtaat tggctgttac tgtagcagtg gttggcgctt
     2821 cgctttctct ataaactaag gtcactgttc taccttcgct tacaatattc ccagttaaac
     2881 ttgcagaatt tgtatctgct tctttaaaag tataatattt tccgtcagta gtagtcatgc
     2941 tactgagttt tttatctgtg acattgtagc tggtaccaat cagttgtttt ttattggtaa
     3001 tgtaggttcc gtcactttct ttttctccaa ttccagtatc atttttcaat gatagcaaac
     3061 gcccttgttc atcaacatag cgaactttca cattttctga gattagttct gccaattctg
     3121 aggttttttt ctttttcttg atttcttcgg ttattttccc tttctcttct tcgggaatat
     3181 ttagttttgg aatgattttt tcaacaacgg ttcgtgatgg ttccacagta tcttggatga
     3241 ctgaaaagtc agctagaatt ggaagattat actgaacacg gtgactttga gtgtttactc
     3301 ctactctttc attattctct gaaaatactt gtacggtata agaaacaaca tcttttccta
     3361 atagaacatc cccagtagag aaatagccgc cttttcctag tttgctatct ccagagccca
     3421 cttctttcct aatcttatca gatagttttt taccagtcag tacattcgtt cgcacaatcc
     3481 ctttgtctac ccctacaaag tgggagaact ttttgaactc ttcagaacca gatctagccc
     3541 aaccattatt aagggcattt gcttttgtat ttgtattctc tctcaaaagt ttggcgatta
     3601 gaattatatt catcggcact tagagttgct gctatatctg actcttgaat accaacttcc
     3661 ttactaccat ttctagcggc agtatatgtg tatttatctg tttctacttc tagctgatta
     3721 tccttaacat gataggtaat tttctcctgg tataagagtc ttcagtagtt tatatactct
     3781 gtcatcatct ttagctttag aagcagctga gtttagccaa gttggggtat taggagtatc
     3841 tttatcagcc tgtttcaaga cattattcaa gtcatttgct agcctattgg ttatcctcac
     3901 tgtgaaagtt ttcttccagt ctgaaccact tttattagac ttagatatgc tcatgaaatc
     3961 ctggtcaaca ttcaacacaa tatcgccttg ttttttagca tcttccgttg cttctgcttc
     4021 aaattgatca tggagttttt gttgctctgg tgtatagttt ttttatttac acgatttaat
     4081 gtactatttt ttattttagt attaagaact ccattaatac gatttttaaa ctctgcttca
     4141 aaaaatccct taatttgttg gtgcgcaagt tcaacattca aacctttctt atacaagtct
     4201 tcattctgaa cgatttcggc tacacggtga atggtttgat tgtataccgt cttctcttaa
     4261 ccagcagtat ccttagtttt aatgactact cgataggttc ctttagaacc gttatagtca
     4321 tctagtttta aaaaagcatt ccaaacattc aaaaatagtt ggaacttccc ttaataaatc
     4381 cgtcactttc tttttcaaga tagcccaagc ttgctcaata ggattcaaat ccggtgaata
     4441 aggtggtaga ggtaagaaaa agtgtttatc ttggatgcag agttcatcca aaatgttctt
     4501 gggatgaaaa ccagcattgc ccatgacaat aacatgaggt gtcttcaaag caggtaggag
     4561 ttgcgttttg aaccactcca caaagaaatc gcttgtcatg cttttcttgt aaatcatggg
     4621 agctataaac tctccgtcta cttgtcctgc aacaattgaa gttcgctcaa aacgacgtcc
     4681 gctaatcttt tcatagactt tctcccctct aggagcccct gcataaggac gatagagata
     4741 gcggtcgatt cctgtttcat caatataaac aggtgctagg tgctttaaac tattaaaatt
     4801 cttaagaaat aaggctactt ttctgggtct tgttccttaa agctcctcat ctttttttaa
     4861 agtgacctta atctgcttta aagctgccca tactgaagga acagcacaat caaaatgtgc
     4921 cgcaatttcc cgtaaaaaag catctggatg agcctctaca aaggctttca attcctctaa
     4981 aggaatcttt cggtttttga cgactcgctt tttcctctct atgtgttctt gttcacgtct
     5041 ttcttttccc acgtgaagag agttctgacg ccaacaccaa aaaacttggc tgcctcgaca
     5101 tggctgtgcc cctctttgat gtaatctaat gctcgctgtt taaaatcagt actatatgcc
     5161 atagctttat tataatatgc ttgtttaaaa ctaagtaact atatcaatgt tttgttatga
     5221 gaagacttac tttttttact gaaattgaat ttttcctagc ctcaacatca tataacccca
     5281 aaattcaatc tgacctggtt tgaagagatt ttcgaagcag ataaggtttt actaaaacta
     5341 aaaaaaatga tataattaaa ctgattaaat gttttaaaaa taaaggagaa tttgaatgtc
     5401 ttaccaagaa aattaccaga aatgggttga ttttgtggag cttcctgact accttcgtca
     5461 agatttggaa aatatggacg aaaaaactaa ggaagatgcc ttctatacaa atcttgaatt
     5521 tggtactgca ggtatgcgtg gcttggttgg tgctggtaca aaccgtatca acatctacgt
     5581 tgttcgccaa gctactgaag gattggctcg tttgattgag tcaaaaggtg gaaacgagaa
     5641 agaacgcggt gtagcaattg cctacgatag ccgtcacttc tcacctgagt ttgcctttga
     5701 atctgcggca gttcttgcta aacacggcat caaatcttac gtatttgaaa gccttcgtcc
     5761 aactccagaa ctatcatttg cagttcgtca tctcaactgt ttcgcaggta tcatggtcac
     5821 agccagccac aaccctgctc catttaacgg ttacaaggtt tacggtgaag acggtggaca
     5881 aatgcctcca cacgatgcgg acgctttgac tacttatatc cgtgcaatcg aaaacccatt
     5941 tgcagttgaa gttgctgatg tggaaactga aaaagcttct ggcttgattg aagttatcgg
     6001 cgaagctgtt gacatagaat accttaaaga ggttaaggac ataaacatca acccagcctt
     6061 gattgaagaa tttggtaaag acatgaagat tgtctacaca ccacttcatg gtactggtga
     6121 aatgttggct cgtcgtgctc ttgcccaagc aggatttgac tctgttcaag ttgttgaagc
     6181 gcaagcaact gctgacccag acttttcaac tgtaacatct ccaaacccag aaagccaagc
     6241 agcctttgcc cttgctgaag aacttggtcg tcaagttggt gcagatgttc ttgtcgcaac
     6301 tgacccagac gctgaccgtg ttggtgttga agttcttcaa aaagatggta gctacctcaa
     6361 cctttcaggt aaccaaatcg gtgctatcat ggctaaatac atcttggaag ctcacaaaaa
     6421 cgctggaact cttcctgaaa atgccgctct ctgcaaatct atcgtttcaa ctgacttggt
     6481 aacgaagatt gctgaaagct acggcgcaac tatgttcaac gtcttgacag gtttcaaatt
     6541 tatcgctgaa aaaatccaag aattcgaaga aaaacacaac cacacttaca tgatgggatt
     6601 tgaagaaagc ttcggttact tgattaaacc atttgtacgt gataaagatg ccatccaagc
     6661 cgttcttgtc gttgctgaac ttgctgccta ctaccgttct cgtggtttga cacttgctga
     6721 cggtatcgaa gaaatctata aagaatatgg ctactacgca gaaaaaacaa tctctgttac
     6781 tctttcaggt gtcgatggtg ctgaacaaat caaagcgatt atggctaaat tccgcaacaa
     6841 tgctccaaca gaatggaacg caacagctat cactgtcgta gaagacttca aggcacaaac
     6901 tgctactgtt gctgacggta ctgttacaaa cttgacaact cctccaagtg atgtgttgaa
     6961 atacacactt gctgacggtt catggattgc cgttcgccct tcaggtacag aaccaaaaat
     7021 caagttctac attgcagttg taggggaaac caacgaagaa tcacaagcta agattgctaa
     7081 catcgaagca gaaatcaatg catttgtaaa ataaagacct ataaaagatg agaccaacca
     7141 acctcatctt ttttcgtatc aaatctaagc aattttagaa actttatggc atactagact
     7201 tatcaatgaa agcgaggtaa tctcatggaa caatttttgg ataacatcaa agaccttgaa
     7261 gtcactacag ttgtgcgtgc gcaagaagct cttgataaaa aagaaactgc aaccttcttt
     7321 atcggtcgca aaacttgccc ttactgccgt aaatttgcag atacattgtc aggtgtcgta
     7381 gctgaaacca aagctcacat ttacttcatc aatagtgaag aaccaagcca actcaatgat
     7441 ttgcaagcat tccgctcacg ctatggaatc ccaactgtac caggttttgt tcatattaca
     7501 gatggacaaa tcaacgtccg ttgcgactct tcaatgtcag cacaagaaat caaagatttc
     7561 gcaggattgt aaaaaatcag ctaacaagtc ttaaaatcac aaaaacgcat aatgtaaggt
     7621 gcaaaaacct tgatattatg cgttttattg ttcctaaaac agttacatca gcatttcatt
     7681 acagaacatt ttaattttgg aagtcaaatc aatttttaac aatgttttag aaatcacagt
     7741 gggctattcc atattcaatt atccatattc aatcgctatt atcgttttcc tagattacaa
     7801 aaaaactacg ttttgctaat caaaacgcag tttcagccac tattttatct tactgtcctt
     7861 cttttacttc tttggttgct acatcttctc caaaccattt ttggctgatt tcttggaact
     7921 tgccgtcctt gtaaagacta gaaaaagctt catttatctt cttaaccaag gttgtatctt
     7981 ccttacgggc tccaaccgca aaagcttctg tttctagtcc aactgtaaag acattataat
     8041 cgtttaaaac accttctgct tctaaataat agtttgcata gacacggtca atcaatagac
     8101 catcaattcg atcgtttttc aaatcaatca aggcttcatt aaaggtttgg tattgattcg
     8161 cttccttatt agcgacaata ttcttcaaaa tttctggatt tgcttcaaag tccgcataac
     8221 cagatgaacc agcttgagct cctaatgtct ttccagtcat atcctttgca gtcgtgatac
     8281 cagatgattt cttcgtaacc aatacctgct cattcttcat atatgagtta ctgaaagcca
     8341 ccttttcacg gcgttcgtct gtagcggaat agccattcca aatcagatca atcgttcctt
     8401 ttgtcaattc agcttctttc aaatcccaat caatcggttg ccaatttacc gtgattccgt
     8461 atttttcaaa aacagctgta gctaaatcaa tatcaaatcc tgcataagaa ccatctttct
     8521 gagcaaatcc cattggaaca aaagtactat caaatccaat agtaatagac ttgttagact
     8581 ggtactttga ccaattatct ccactagttt cgctagaatt tttcccacaa gctactaaga
     8641 acaaagcagt catcagactg actaatacaa gcatccattt tttcatccat ttttcctcct
     8701 atttaggttc tactttcaat aatacatctg cgatattttc agcaaactgc aaatcatggg
     8761 taaccacaat ctgggtcatc ccaagttccc tattttgcaa gattagcttc tccacttcca
     8821 aacgtaattc tggatccagg gcagaagttg gttcatcgta gccaatgatt tctgggtcaa
     8881 tcatcatagc acgcgccaaa gccacccgct gcttttgccc accagatagt gagaaaggat
     8941 aggcctctgc gtgtcctcct agtcctaact gttccaagag ttcactcgcc ttcttctcag
     9001 cctcttcctg cttcattccc atggtcttca caggcgataa agtcaaattt tccagaactg
     9061 atagatgagg aaatagttga aaatcttgga agacaaatcc cagtaggttg cgcttctgca
     9121 attcatccag ctctaaaggt tgtccattat aaaagatttg ccctgaatca atggtttcaa
     9181 gacctgcaag catacgtaaa agagttgtct tacctccacc agaaggtcca acgatagcca
     9241 ggatttgctt ttcaggaata cttagactga aatcagacag gatttgtttg tctccaaaga
     9301 ctttattgat atttcgtaat tctaacatag ctgcccccta tctataataa ctgtactttt
     9361 tctcaacttt tttggaaata attgtcacaa tcccaattaa aatcaagtaa atggctcctg
     9421 ccaagaacat aggaaccaga ctagcatcgc ggttagcagc tgttcgacta gccaagataa
     9481 ggtctgaaat tccgagagca tagaccaaag aagtatcctt gaccaaactc ataacttcat
     9541 taaagacact aggaagaacg atcttggtca cttggggcaa gataatatag cgcactctgt
     9601 caaaagggct aaacttcaag accttggcag cctcatactg tcctcttgga atagtgtcaa
     9661 ttcccccacg gaaaatttct gcaaagtaag ctgcatagtt gagaacaaag gcaataatag
     9721 ctgcaggaag gcggtctaaa cgaatcccaa tacttgggag cacataatag ataaaaatca
     9781 gttgcaagag taagggggtt cctcgcataa cccagatgta aatgttaatc agataatgga
     9841 ggggcttcca atggacttgc aaggcaaagg caatcaaaac gcccaaggga atcgaaaata
     9901 gcaagaccag tgcaaagacc tgtacagtcg tgctcgcacc attcagtaaa ctcggtaata
     9961 tctcaaataa ataagacata ctgcacctcc taaaagtaat tgttcctatt atagcatgaa
    10021 taaacaagat taccaagtat ttttgtaaaa agattctacc atatacaaat aaaaaccgta
    10081 gctatcaaaa gagataaact acagttctat atgtttaaac attcttacaa tctctcaaac
    10141 agttcttgca tttgcacatc atctggaacc agttttaagt aagtgtgagc atggactttt
    10201 gcttcttcaa aatgtcccaa ttcacgcaag agatagatat agtgttccag aaattctgga
    10261 ttgtccttca aatctcctgt caactcttga taatgctcat aagcagtatc caaatcgtcc
    10321 atttcttgat aagaacgagc aatcatccac ttggtcaaaa gattttctgg ctcctcactc
    10381 tgcaagtcta gaatatcctc ataacgctcc tgctccagat aaatagtggc taaacgaagc
    10441 aagatttctt ctgtatcctc agcgtcttct tttgcagtaa ggagataatt ttctgcacca
    10501 ctagcatcat gcaattcata agaaaattgt gaagcagcta gcaagaggcg agtttcaaag
    10561 ggatttttct ctaatccttg cttagcgata cgcagggctt cttgaacttg atgttcctta
    10621 tgtaaagcct gactgtaccc atactcatag ccttcaaagt caggagaaat ggtatcaagc
    10681 tgcttaaagt agagggtggc tttttgatat tcttcttgat caaaataaag actggccaac
    10741 tcaaaagctg ttaagtcatc gtattctaac tccagggctt tttctaaaaa ctcagtagcc
    10801 gtttcaaatt tccctaactg agcataggca aagccaattc gttgataggt ggaaatgccc
    10861 gtttgctcat aaatcgagcg attatctaac tgggcatagg cttgaatagc cgcttggtaa
    10921 ttttccaact cactatccaa ctctgccaaa cccaatatca agagagaatc ctctgagtag
    10981 gtcaaggcct ccaataattt ctcacgtgcc acatctgtca aaccttccag ctggtaaagg
    11041 tctgccttca aaaccaaaga cgagacatac cagtcactgt cagcttggat ttcctcaaga
    11101 taggtaaagg cttcttctat ttgaccatcc tcgctagcaa ttgcagctag attaagatga
    11161 acctctggaa aatcctctac aattttcagg taaatttcct tggcctgagg atagaaacca
    11221 atcccttcaa gataagttgc caactcatac agaagattac ttgaatcatt ttctaaagct
    11281 ttggcgaaat aatgctcagc cttagttaaa tcttgctcct ccaaagcctg taacatctgt
    11341 tgactattgt tcactcttga cttcctcacc ctctaattca tatagaccac tgactacctt
    11401 ataccattcg aaaatggctg aaatgacaac cttagcagag gcataaaccg gaataccaag
    11461 taaaactccc cagataccaa acatagatcc tgaagttaac aaaacaaaga gaacattaat
    11521 agggtggatg tttaattgac ttcccaaaat caatggagag acaaaacggc cttcaatagt
    11581 ttgttctacg ataaagacaa tcactacttt caaaagcatg actggaccag caatcaaacc
    11641 caatactaga gcaggaagca tggctagaaa gctaccaaga taagggacca gatttaaaat
    11701 accagcagta acccccagcg taaccgcata gcgtagacca ataatcttga agaagatgat
    11761 aaacattact gctacaataa tagccactgt cacttgccct cgaacatagt tggacaactg
    11821 ttgattcaca tctgatagaa cttgtccaac aggttccttc aattttcttg gaatgaattg
    11881 ggtcaaatag ttacgcaagc ctttcccatc acgcaagaga taaaagagca tgaaaggaac
    11941 gataatcaag gcaacaatca cttgagaagc tccgctaata aaggcactca cccagttgac
    12001 tgcctgagat gaaaccttac ttgccaaaac tgtagcctgg ctagaaaaat tggtcaaaac
    12061 ttgctctaat tgaggtctga aatcatctgg caggtgctgg gctaccaatc cattaacaat
    12121 cctatctata tcttctaagt aaacaggaac gtttcttgca aaggtcaaaa cctgacgttg
    12181 cagatttgga atggcgactg ccaagcccca aatgataaag agagcgatga taacaaagac
    12241 aatagtgata gctataacac gattaacctt atgcttctcc atccaatcaa caataggatt
    12301 caacaaataa tataacaaac cagacaaaat gactggcaac atcacaactg ctaaaaagtc
    12361 taaaacaggt gaaaatagaa aactaatctt acttaaaata aaaagattca gtcccaataa
    12421 taaggttact aaaaataccg taattgcctt gttatctaaa aaccacttga aaaaccaaga
    12481 taggctaaaa tgtttctctt tttgctccat aaatacttcc tttctattgt tctctcatta
    12541 taccattttt gaaacaaaat aactcttttt taaagtgctt acatctaatt ggatatcttt
    12601 aatttacttg tttttgtgat ataatagtct tatctttaca cagaggtata gtaatgaaag
    12661 aaactgttta ttttggaact tatacacgtc gtacttctca agggatttac aaggcagact
    12721 ttgatacaga aactggtcag ctttcaaatc tagaactttt tgcagctgag ccaagtccaa
    12781 cctaccttgc ctttgaccag caccaacatt tatacactgt tggtagccaa gacgataagg
    12841 ggggaattgc agcctatcaa actgacggga ctgtgttaaa tcatgttgtt gaaaaaggag
    12901 ctccccactg ttatgttgct gtcgatgaaa agcgtgattt ggtttacgca gccaactatc
    12961 acaagggaca agtccttgtt tataaacgcc aggaagatgg tagtcttcta cttagtgata
    13021 tggatcaaca cagtggccaa ggtccacatg aaaatcaagc ttccccccat gttcactata
    13081 cagatttaac acctgaccac tatctagtga cctgcgactt gggaactgac caagtcatca
    13141 cctatgacct cgatcaagaa ggaaaattat ctaagctcta tacctatcac agcaagccag
    13201 gagcaggctc acgccatatc attttccata accactataa aatcgcttat ctcatttgtg
    13261 aactcaatag tactatcgaa gttttaatct acgatggcgt tggcgaattt gaacgtatgc
    13321 aggtcatttc aactttaccg gaagcttacg aaggctttaa tggaaccgct gctattcatc
    13381 tctctaaaga cggtaaatac ctctacgctt ctaaccgtgg ccatgattct atcgcagtat
    13441 ataccatcct tgcggacggt agcttagagt tattagaaat cgttccaacg catggtcaga
    13501 ctccacgtga ttttgatttg acacccgacc aaaaatttct cattgttgtc catcaagact
    13561 ctgacaatgc aactgtcttt aaacgtaatt gtgacaatgg tcgtctagca gaactctcca
    13621 acgacttcca tgttcccgaa gcagtctgca tccgttttgc tccttaaaac accataaaaa
    13681 atggttctat aatatttgta gtgggtaaa
//
LOCUS       DBEJHE010000043        13533 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC4 isolate 671759
            SAMN38261586-rid24793303.denovo.43, whole genome shotgun sequence.
ACCESSION   DBEJHE010000043 DBEJHE010000000
VERSION     DBEJHE010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261586
            Sequence Read Archive: SRR26833752
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 13533)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13533)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576136.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576136.1
            Genome Coverage       :: 109x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 19:48:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,067
            CDSs (total)                      :: 2,029
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 131
            CDSs (without protein)            :: 131
            Pseudo Genes (ambiguous residues) :: 0 of 131
            Pseudo Genes (frameshifted)       :: 64 of 131
            Pseudo Genes (incomplete)         :: 59 of 131
            Pseudo Genes (internal stop)      :: 46 of 131
            Pseudo Genes (multiple problems)  :: 32 of 131
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13533
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261586-rid24793303.denovo.43"
                     /strain="GPSC4"
                     /isolate="671759"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            <1..240
                     /locus_tag="ACL3EZ_001826"
     CDS             <1..240
                     /locus_tag="ACL3EZ_001826"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0393353.1"
                     /translation="NSPCCGWILFSLLILFETLFKPRQLHLAVYVLLTSSVLSTTSKQ
                     CFELTSSVLSATSKQCFEQPAASFLVCSLIFIEYY"
     gene            298..954
                     /locus_tag="ACL3EZ_001827"
     CDS             298..954
                     /locus_tag="ACL3EZ_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HGR0393354.1"
                     /translation="MPTALGYVSIGLACGIIGAPYVTPVEMGLMSLFVYAGSAQFAML
                     ALIVVQAPVAAIAMTVFLINLRLFLLSLHASTYFRHTSLWHNIGMSSILTDETYGVLM
                     GELAHTDKVNPMWMHGNNLNSYVAWFVGTVVGTALGDLLPNPEIFGLDFALVGMFIGI
                     FASQFQMMQRRISVRNLLIILAVVAVSFFLLLTVVSQSLAVLFATLLGCSMGMVLDGQ
                     "
     gene            944..1267
                     /locus_tag="ACL3EZ_001828"
                     /pseudo
     CDS             944..1267
                     /locus_tag="ACL3EZ_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000253911.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
     gene            1371..2201
                     /locus_tag="ACL3EZ_001829"
     CDS             1371..2201
                     /locus_tag="ACL3EZ_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HGR0393355.1"
                     /translation="MKKIVKYSSLAALALVAAGVLAACSGGAKKEGQAASKKEIIVAT
                     NGSPRPFIYEENGELTGYEIEVVRAIFKDSDKYDVKFEKTEWSGVFAGLDADRYNMAV
                     NNLSYTKERAEKYLYAAPIAQNPNVLVVKKDDSSIKSLDDIGGKSTEVVQATTSAKQL
                     EAYNAEHTDNPTILNYTKADFQQIMVRLSDGQFDYKIFDKIGVETVIKNQGLDNLKVI
                     ELPSDQQPYVYPLLAQGQDELKSFVDKRIKELYKDGTLEKLSKQFFGDTYLPAEADIK
                     "
     gene            2355..3209
                     /locus_tag="ACL3EZ_001830"
     CDS             2355..3209
                     /locus_tag="ACL3EZ_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HGR0393356.1"
                     /translation="MKIKKWLGLAALATVAGLALAACGNSEKKADNATTIKIATVNRS
                     GSEEKRWDKIQELVKKDGITLEFTEFTDYSQPNKATADGEVDLNAFQHYNFLNNWNKE
                     NGKDLVAIADTYISPIRLYSGLNGSANKYTKVEDIPANGEIAVPNDATNESRALYLLQ
                     SAGLIKLDVSGTALATVANIKENPKNLKITELDASQTARSLSSVDAAVVNNTFVTEAK
                     LDYKKALFKEQADENSKQWYNIIVAKKDWETSPKADAIKKVIAAYHTDDVKKVIEESS
                     DGLDQPVW"
     gene            3309..4682
                     /locus_tag="ACL3EZ_001831"
     CDS             3309..4682
                     /locus_tag="ACL3EZ_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HGR0393357.1"
                     /translation="MVFPSEQEQIEKFEKDHVVQHYFEVLRTLISKKSVFAQQVGLKE
                     VANYLGEIFKRVGAEVEIDESYTAPFVMAHFKSSRPDAKTLIFYNHYDTVPADGDQVW
                     TEDPFTLSVRNGFMYGRGVDDDKGHITARLSALRKYMQHHDDLPVNISFIMEGAEESA
                     STDLDKYLEKHADKLRGADLLVWEQGTKNALEQLEISGGNKGIVTFDAKVKSADVDIH
                     SSYGGVVESAPWYLLQALQSLRAADGRILVEGLYEEVQEPNEREMALLETYGQRNPEE
                     VSRIYGLELPLLQEERMAFLKRFFFEPALNIEGIQSGYQGQGVKTILPAEASAKLEVR
                     LVPGLEPHDVLEKIRKQLDKNGFDKVELYYTLGEMSYRSDMSAPAILNVIELAKKFYP
                     QGVSVLPTTAGTGPMHTVFDALEVPMVAFGLGNANSRDHGGDENVRIADYHTHIELVE
                     ELIRSYE"
     gene            4675..5736
                     /locus_tag="ACL3EZ_001832"
     CDS             4675..5736
                     /locus_tag="ACL3EZ_001832"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HGR0393358.1"
                     /translation="MSRDIIKLDQIDVTFHQKKRTITAVKDVTIHIQEGDIYGIVGYS
                     GAGKSTLVRVINLLQKPSAGKITIDDDVIFDGKVTLTAEQLRRKRQDIGMIFQHFNLM
                     SQKTAEENVAFALKHSELSKEEKKAKVAKLLDLVGLADRAENYPSQLSGGQKQRVAIA
                     RALANDPKILISDESTSALDPKTTKQILALLQDLNQKLGLTVVLITHEMQIVKDIANR
                     VAVMQDGHLIEEGSVLEIFSDPKQPLTQDFISTATGIDEAMVKIEKQEIVEHLSENSL
                     LVQLKYAGSSTDEPLLNELYKHYQVMANILYGNIEILDGTPVGELVVVLSGEKAALAG
                     AQEAIRQAGVQLKVLKGGQ"
     gene            5738..6430
                     /locus_tag="ACL3EZ_001833"
     CDS             5738..6430
                     /locus_tag="ACL3EZ_001833"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter permease"
                     /protein_id="HGR0393359.1"
                     /translation="MESLIQTYLPNVYKMGWSGQAGWGTAIYLTLYMTVLSFIIGGFL
                     GLVAGLFLVLTAPGGVLENKVVFWILDKITSIFRAIPFIILLAILSPLSHLIVKTSIG
                     PNAALVPLSFAVFAFFARQVQVVLAELDGGVIEAAQASGATFWDIVGVYLSEGLPDLI
                     RVTTVTLISLVGETAMAGAVGAGGIGNVAIAYGFNRYNHDVTILATIIIILIIFAIQF
                     LGDFLTKKLSHK"
     gene            complement(6459..7028)
                     /locus_tag="ACL3EZ_001834"
     CDS             complement(6459..7028)
                     /locus_tag="ACL3EZ_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HGR0393360.1"
                     /translation="MKKSILTTLLFAVLYFLCMGIGVLLGNLFDQTGNMFYAPAFTAL
                     VGGSVYMILVAKVPRFGAITTIGLVIALFFLGTKHGAGSFLPGIICGLLADEVAHLGK
                     YKDKTKNFLSFIIFAFSTTGPILLMWIAPKAYMATLLARGKSQEYIDRIMVAPNPGTV
                     LLFIASIVIGALVGALIGQALSKKFAQKI"
     gene            7163..7777
                     /locus_tag="ACL3EZ_001835"
     CDS             7163..7777
                     /locus_tag="ACL3EZ_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000532354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HGR0393361.1"
                     /translation="MGRFLDFVFNRFFLGMIATAFFWLLTLAGGIILGLAPASATLMS
                     LYAEHGYSFREYSLKEAWSLYKQNFVSSNLIFYSFLGVGLVLTYGLYLLVQLPHQTIV
                     HLIATLLNVLVVALIFLAYTVSLKLQVYFALSYRNSLKLSLIGIFMSLAAVAKILLGT
                     VLLVAIGYYMPALLFFVGIGMWHFFISDMLEPVYEIIHEKLATK"
     gene            7755..9425
                     /locus_tag="ACL3EZ_001836"
     CDS             7755..9425
                     /locus_tag="ACL3EZ_001836"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HGR0393362.1"
                     /translation="MKNWRQNRMKQFWLHTLLRTYSSVMIIIIASFAILLSYADWDSR
                     EKEAQRVAQRVTARTVSEIEYYHRESTQIAQALVENQARIEGIYKYFSLSMPDYFYWQ
                     LERKASPYISVSLYENVDDLYVRNDFVTGVAIAFQDYKEVYVSTKDKRSGEKIRAEDF
                     KPAGNSFAIPVSDPVSDQDLGVIYISLDPAVLYHAIDNTRGHTPMAVTVTSPFDTEIF
                     HIGETVDKESENWLVGLTSHGYQVQVAVPKNFVLQGTVTSSALIVGLSLLFIVILYLT
                     LRQTFANYQKQVVDLVESIQVIAQGEEGRRIDISEKDQELLLIAETTNDMLDRLEKNI
                     HDIYQLELSQKDANMRALQAQINPHFMYNTLEFLRMYAVMQSQDELADIIYEFSSLLR
                     NNISDERETLLKQELEFCRKYSYLCMVRYPKSIAYGFKIDPELENMKIPKFTLQPLVE
                     NYFAHGVDHRRTDNVISIKALKQDGFVEILVVDNGRGMSAEKLANIREKLSQRYFEHQ
                     ASYSDQRQSIGIVNVHERFVLYFGDRYAITIESAEQAGVQYRITIQDE"
     gene            9437..10723
                     /locus_tag="ACL3EZ_001837"
     CDS             9437..10723
                     /locus_tag="ACL3EZ_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HGR0393363.1"
                     /translation="MYKVLLVDDEYMVTEGLKRLIPFDKWDMEVVATASHADEALEYV
                     QENPVDVIISDVNMPDKTGLDMIREMKEILPDAAYILLSGYQEFDYVKRAMNLSVVDY
                     LVKPVDKVELGNLLEKIAGQLGERGKKSQTLSQELDEAGFVSYLGDKENWWIGLSKEK
                     QGSFAIPYYVLGQDWQIFISDQPLDGLVVTPFEAPYQEHFERWKLNAEKTLFYGSVNL
                     QQSESLFAYYEPIYRVIIQGNLNQIVEELNLLEKVVLENTPRVPITKQLFIQFVMDVF
                     HLFEHLKADDLTDIVKTIHAIQSFDELVPYIKETLTSFFGQYRMNENVVSVLEVIGRD
                     YQKELSLKDISKALFINPVYLGQLIKRETDSTFAELLNKQRIKAAQQLLLSTSDSIED
                     ICYAVGYSNLGYFYKVFRKLCGKSPKAYRKQVETIL"
     gene            10775..11308
                     /locus_tag="ACL3EZ_001838"
     CDS             10775..11308
                     /locus_tag="ACL3EZ_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000729030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0393364.1"
                     /translation="MKKKPIYLWVLLILSALISVPSLFGIVSPLPSKEALRAAQKQVA
                     GVNAQQLEDQLNYTYRVAEASHSIFNVALIVLSTILVVVAIVFLVRKNLQYANYTYVG
                     YVLLAIIGSIYGYVGLQDAVQLVQDESMRLTVSIGSKAVSIFYIVINVLFLALVFYKM
                     WRQQKALAEEEETEELT"
     gene            11386..11856
                     /gene="nrdI"
                     /locus_tag="ACL3EZ_001839"
     CDS             11386..11856
                     /gene="nrdI"
                     /locus_tag="ACL3EZ_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HGR0393365.1"
                     /translation="MKTISLVYISLSGNTESFVTRLKDYLLSQYKGIEVQKIHIKDLV
                     KEGKNFYEMDHPYVAFLPTYLEGGNGVDNGDVEILTTPVGDFIAYGNNASKCFGVVGS
                     GNRNFNNQYCLTAKQYSQRFGFPVLADFEMRGMLEDIKHVAAIIADLYELEKEN"
     gene            complement(12149..13411)
                     /locus_tag="ACL3EZ_001840"
     CDS             complement(12149..13411)
                     /locus_tag="ACL3EZ_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000075801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NRAMP family divalent metal transporter"
                     /protein_id="HGR0393366.1"
                     /translation="MSQAISLNQSTWASKLKAMGPGILMATAAVGGSHIVSSTQAGGS
                     YGWSLLLLVILANVFKYPFFRFGAEYTADTGKTLVEGYAEKGKLYLWIFFILNVFSAM
                     VNTAGVAILCSAIIASAFPMIGLSITQWSLILVAIIWAMLLFGGYKLLDGMVKWIMSA
                     LTIATVLAVIIAAVKHPEYSSDFVEKTPWQMAALPFIVSLLGWMPAPIEISAINSLWS
                     AEKRKTVNFNTEDALFDFNTGYIGTAILAVFFVALGALIQYPTGQAVEAASAKYISQF
                     VGMYASVLGEWSRYLITFIAFLCIFGTVITVIDGYSRVNQESLRLLISQKEDNRKSLN
                     IWMTITAIIGIVIIKFFAGQVSTMLRFAMIGSFLTTPFFALLNYALVTRENKNLPSWL
                     KHLAIAGLIFLFGFAIFFIYALAIGKAG"
BASE COUNT         3955 a         2535 c         3099 g         3944 t
ORIGIN      
        1 aatagtccat gctgtggctg gattcttttc agcctactta tactcttcga aactctcttc
       61 aaaccacgtc agcttcacct tgccgtatat gtgttactga cttcgtcagt tctatccaca
      121 acctcaaaac agtgttttga gctgacttca tcagttctat ctgcaacctc aaaacagtgt
      181 tttgagcaac ctgcggctag tttcctagtt tgctctttga ttttcattga gtattattaa
      241 gacaatatga ggagaaagat gaaagaaaaa ggattttagg agggggcgca ggcagccatg
      301 ccaacggctc ttggctatgt cagtatcggc ctggcctgtg gaattatcgg tgcgccctat
      361 gtgacacctg ttgagatggg cttgatgagt ctctttgttt atgctgggag tgcccagttt
      421 gccatgttgg cactgattgt ggttcaagct cctgtggcag ctattgctat gacggttttt
      481 ctaatcaatt tgcgtctctt tttgttgagc ttacacgcat cgacttattt ccgtcatacc
      541 agtctttggc acaatatcgg tatgtctagt atcttgacag atgagaccta tggcgttttg
      601 atgggcgaat tagcccatac agataaggtc aatccgatgt ggatgcacgg gaacaatctc
      661 aacagctatg tggcttggtt tgtgggaaca gtggtcggaa cggctctagg tgacctgttg
      721 ccaaatccag aaatctttgg tttagatttt gccctggttg ggatgtttat cgggattttt
      781 gcttcgcaat tccagatgat gcaaagacgg atttctgtcc gcaatctgct cattatctta
      841 gcagttgttg cagtgtcctt ctttttactt ttgacagtgg tgtctcagtc actagctgtt
      901 ctgtttgcga cgctacttgg ttgtagcatg gggatggttt tagatggtca gtaagtatct
      961 tttattagca gttattttct ctggtcttgt gacctggatt ccccgtatga ttcccttcat
     1021 cttggtcaag tataagggcc tgcctacgat tgttgagcgt tttttgaagt ttttgcctgt
     1081 ttccattatc tttgccttga ttctttcaag agtagtgaca ggtaaggttg ggaaccttcc
     1141 tcaaatcaaa tgactggact tcttagcagt ctttccaaca gcttgggtag cttttcgcta
     1201 ccgcaatcta gtcggtacgg ttctctttgg agtagtcttg attgccgtct tgcgtttggt
     1261 cttttaaata agtcataaag aaaacttatc acagagatag atatcatata atggcgtaat
     1321 tacttttttt ctgataagat tataaggtat tctattttgg aggaaatgac atgaaaaaaa
     1381 tcgttaaata ctcatctctt gcagcccttg ctcttgttgc tgcaggtgtg cttgcggctt
     1441 gctcaggtgg tgctaagaaa gaaggacaag cagctagcaa gaaagaaatc atcgttgcaa
     1501 ccaatggatc accaaggcca tttatctatg aagaaaatgg cgaattgact ggttacgaga
     1561 ttgaagtcgt tcgcgctatc tttaaagatt ctgacaaata tgatgtcaag tttgaaaaga
     1621 cagaatggtc aggtgtcttt gctggtcttg acgctgaccg ttacaatatg gctgtcaaca
     1681 atcttagcta cactaaagaa cgtgcggaga aatacctcta tgccgcacca attgcccaaa
     1741 atcctaatgt ccttgtcgtg aagaaagatg actctagtat caagtctctc gatgatatcg
     1801 gtggaaaatc gacggaagtc gttcaagcca ctacatcagc taagcagtta gaagcataca
     1861 acgctgaaca cacggacaac ccaactatcc ttaactatac taaggcagat ttccaacaaa
     1921 tcatggtacg tttgagcgat ggacaatttg actataagat ttttgataaa atcggtgttg
     1981 aaacagtgat caagaaccaa ggtttggaca acttgaaagt tatcgaactt ccaagcgacc
     2041 aacaaccgta cgtttaccca cttcttgctc agggtcaaga tgagttgaaa tcgtttgtag
     2101 acaaacgcat caaagaactt tataaagatg gaactcttga aaaattgtct aaacaattct
     2161 tcggagacac ttatctaccg gcagaagctg atattaaata atttcttgaa atcatccatt
     2221 ctgagtaaga tgggtggttt ctcagttttt agggatatag ttttaaacta tatatctgac
     2281 tatctaataa caatttgtga aatcaaacaa attgtgagat actagtacgg tattattttt
     2341 aaggagaaag aatcatgaaa atcaaaaaat ggcttggtct agcagccctt gctacagtcg
     2401 caggtttggc tcttgcagct tgcggaaact cagaaaagaa agcagacaat gcaacaacta
     2461 tcaaaatcgc aactgttaac cgtagcggtt ctgaagaaaa acgttgggac aaaatccaag
     2521 aattggttaa aaaagacgga attaccttgg aatttacaga gttcacagac tactcacaac
     2581 caaacaaagc aactgctgat ggcgaagtag atttgaacgc tttccaacac tataacttct
     2641 tgaataactg gaacaaagaa aacggaaaag atcttgtagc gattgcagat acttacatct
     2701 ctccaatccg cctttactca ggtttgaatg gaagtgccaa caagtacact aaagtagaag
     2761 acatcccagc aaacggagaa atcgctgtac caaatgacgc tacaaacgaa agccgtgcgc
     2821 tttacttgct tcaatcagct ggcttgatta aattggatgt ttctggaact gctcttgcaa
     2881 cagttgccaa catcaaagaa aatccaaaga acttgaaaat cactgaattg gacgctagcc
     2941 aaacagctcg ttcattgtca tcagttgacg ctgccgttgt aaacaatacc ttcgttacag
     3001 aagcaaaatt ggactacaag aaagcacttt tcaaagaaca agctgatgaa aactcaaaac
     3061 aatggtacaa catcattgtt gcgaaaaaag attgggaaac atcacctaag gctgatgcta
     3121 tcaagaaagt aatcgcagct taccacacag atgacgtgaa aaaagttatc gaagaatcat
     3181 cagatggttt ggatcaacca gtttggtaat aagaaacagg gaggtgggag agaaaattcc
     3241 acctcttgct tttgtataga gtatagattg taaagaagac tattcgttca tagaaaggta
     3301 gagagaatat ggtttttcct agcgaacaag aacagattga aaaatttgaa aaggatcatg
     3361 tagtccaaca ttattttgag gttttgcgta ccttgatttc taagaaatca gtctttgccc
     3421 agcaggttgg actcaaggaa gtcgcaaatt atctgggtga gattttcaag cgtgttggag
     3481 ctgaagtgga gattgatgag agctatacag cgccctttgt catggcacat ttcaagagtt
     3541 cgcgtccaga tgccaagacc ttgattttct ataaccacta tgacactgtg ccagcggatg
     3601 gggatcaggt ctggacagag gatcctttta cgctttcggt ccgcaatggc ttcatgtatg
     3661 ggcgtggggt tgatgacgac aagggtcata tcacagctcg cttgagtgct ttgagaaaat
     3721 atatgcagca ccatgatgat ttacctgtca atatcagctt tatcatggag ggagcggagg
     3781 aatcggcttc aacagaccta gataagtatt tggaaaagca tgcagacaaa ctccgtgggg
     3841 cggatttgtt ggtctgggaa caagggacca aaaatgcctt ggagcagctg gaaatttctg
     3901 gtggcaataa ggggattgtg acctttgatg ccaaggtaaa aagcgctgat gtggatatcc
     3961 actcgagtta tggtggtgtt gtggaatcag ctccttggta tctcctccaa gccttacagt
     4021 ctcttcgtgc tgcggatggc cgtatcttgg ttgaaggctt gtacgaagaa gtacaagagc
     4081 ccaatgaacg agaaatggcc ttgctagaaa cttatggtca acgaaaccca gaggaagtta
     4141 gtcggattta tggattggag ttgcctctct tacaggagga gcggatggcc tttctaaaac
     4201 gtttcttttt cgagccagcg cttaatatcg aaggaatcca gtctggttat caaggtcagg
     4261 gtgttaagac tattttacct gcagaagcca gtgccaagct agaggttcgt ctggttccgg
     4321 gcctagaacc gcatgatgtt ctggaaaaaa ttcggaaaca gctagacaaa aatggctttg
     4381 ataaggtaga attatactat accttgggag agatgagcta tcgaagcgat atgagcgcac
     4441 cagccattct caatgtgatc gagttggcca agaaattcta tccacagggc gtttcagtct
     4501 tgccgacgac agcggggaca ggacctatgc atacggtctt tgatgcccta gaggtaccaa
     4561 tggttgcatt cggtctagga aatgccaata gccgagacca cggtggagat gaaaatgtgc
     4621 gaatcgctga ttatcacacc catatcgaat tagtagagga gctgattaga agctatgagt
     4681 agagatatta tcaagttaga tcagatcgat gtgacttttc accaaaagaa gagaaccatt
     4741 acagcggtta aggatgtgac cattcacatc caagaagggg atatctacgg aatcgttgga
     4801 tattctggag caggaaaatc aacccttgta cgggtgatta atctcttgca aaaaccatct
     4861 gcagggaaaa ttaccattga cgacgatgtg atttttgacg gcaaggtgac cttgacggca
     4921 gagcagttgc gtcgtaaacg tcaagatatc ggaatgattt tccagcattt taacctgatg
     4981 agccaaaaga cagcagagga gaatgtagcc tttgccctta aacactctga actcagcaag
     5041 gaagaaaaga aggctaaagt agctaagttg ttggacttgg ttggtttggc agatcgtgct
     5101 gaaaactacc cttcacaact atctggaggg caaaaacagc gtgtggcaat tgcgcgtgcc
     5161 ttggccaatg atccaaaaat cttgatttca gacgagtcaa cttctgccct tgatccgaag
     5221 acaaccaagc agattttggc cttgttgcaa gatttgaacc aaaaattagg cttgactgtt
     5281 gtcttgatta cgcatgaaat gcagattgtc aaagacattg ccaaccgtgt ggcggttatg
     5341 caggatgggc atttgattga agagggtagt gtgcttgaaa tcttctcaga ccctaaacaa
     5401 cctttgactc aagactttat ctcaacagct acaggtattg acgaagccat ggtcaaaatc
     5461 gagaagcaag aaatcgtgga acacttgtct gaaaacagtc tcttggtgca actcaagtac
     5521 gctggatctt caacagacga gccacttttg aatgaattgt acaagcatta tcaagtaatg
     5581 gctaatattc tctatgggaa tatcgaaatc ctcgatggta ctcctgttgg agaattggtg
     5641 gtggtcttgt caggtgaaaa agcagcgttg gcaggtgccc aagaagccat tcgtcaagca
     5701 ggcgtacagt taaaagtatt gaagggagga cagtaagatg gaatcattga ttcaaaccta
     5761 tttgccaaat gtctataaga tgggttggtc tggtcaggca ggctggggaa cagctatcta
     5821 cctaaccctc tatatgacag ttctttcctt cattatcgga ggcttcttgg ggctagtggc
     5881 aggtctcttt ctcgtcttga cagcgccagg tggtgtcttg gagaataaag tcgtattctg
     5941 gattttagac aaaattacct caatttttcg tgcgattccc tttatcatcc tcttggcaat
     6001 cttgtcacca ctttctcact tgattgttaa aacaagtatc gggccaaatg cagcccttgt
     6061 cccactttct tttgcagtct ttgccttctt tgcccgtcag gtgcaggttg tcttggctga
     6121 attggatggc ggtgtcattg aggcggctca agcgagcgga gcgactttct gggacatcgt
     6181 gggtgtttac ctatcagaag gtcttccaga tttgatccgt gtgacgactg tgaccttgat
     6241 ttcccttgtt ggggaaacag ctatggccgg tgcggttgga gctggtggta tcggtaacgt
     6301 agccatcgct tatggattta accgctacaa tcacgatgtg accatcttgg caaccattat
     6361 tatcattttg attatctttg caatccaatt cttgggagat ttcttgacta agaaattgag
     6421 tcataaataa aaagagccgc gtggctcttt ttaactgatc agattttctg tgcaaatttt
     6481 ttactcaagg cttgtccaat caaggcaccc actagggctc cgatgacaat acttgcgata
     6541 aatagaagga cagttccagg gtttggagcg accatgatac ggtcgatata ttcttgggat
     6601 tttcctcttg ccagaagagt agccatatag gctttgggcg caatccacat aagcaagatt
     6661 ggtcctgttg tactaaaggc gaaaataatg aaagaaagga agttctttgt tttgtccttg
     6721 tattttccta aatgagctac ttcatctgct aggaggccac agataattcc aggaaggaag
     6781 gaaccagcac cgtgtttagt tcccaagaaa aagagggcaa tgacaaggcc gatagtggta
     6841 atggctccaa agcgcggaac ttttgcgact aggatcatat agacgctacc gccgacaagg
     6901 gcagtaaagg caggcgcata aaacatgttt ccagtttggt caaagagatt gcccaaaagg
     6961 acaccaatcc ccatgcagag gaagtaaaga actgcaaaaa gcagtgtagt taagatagat
     7021 ttcttcatga attgtctcct gataattttt tcacaattct cattgtacca cggtttggtg
     7081 ggattgtaaa tggatactag aagtttttga aaacgcttga aatatgatat aatggtttca
     7141 tagttatttt taggggaata tcatgggtag atttttagac tttgtcttta atcgtttctt
     7201 tttagggatg attgcgacag ccttcttttg gctattaact ttagcaggag ggattatcct
     7261 tggtctagcg ccggctagtg ccaccttgat gagcttatat gcagaacatg gttatagctt
     7321 tcgggaatac agtttgaagg aggcttggtc tctttacaag caaaattttg tctcaagcaa
     7381 cctgattttc tatagctttt taggtgtggg tctagttttg acctatggtt tgtatctctt
     7441 ggtgcaattg cctcatcaga ccattgttca tttgattgcg acccttttga atgtcctagt
     7501 agttgccctg atctttttgg cttatacagt atctttaaaa ttacaagttt attttgcctt
     7561 gtcctatcga aatagtctca aattatcctt gattggcatc tttatgagtc tagcagctgt
     7621 ggccaagatt ctccttggga ctgtgctact tgtagcaatt ggttactata tgcctgccct
     7681 gctatttttt gtaggaattg ggatgtggca tttctttatc agtgatatgt tggaacctgt
     7741 ctatgaaatc atccatgaaa aattggcgac aaaatagaat gaagcagttt tggctacata
     7801 cgcttctaag aacctatagt tcagtgatga tcattatcat tgcgagtttt gcaatcttac
     7861 tctcttacgc tgactgggat tcacgtgaaa aggaagccca gagagtagcc cagcgtgtaa
     7921 ctgctagaac agtgagtgaa attgaatatt accatagaga gtcaacccag atagctcagg
     7981 ctttagttga aaaccaagct cgtattgagg gaatctataa atactttagt cttagcatgc
     8041 cagactattt ttactggcaa ttagagcgga aagcttcgcc ttatatatca gtctctctgt
     8101 atgaaaatgt tgatgacctc tatgttcgaa atgattttgt aactggagtg gccattgctt
     8161 ttcaagatta caaggaagtc tatgtttcta ctaaagacaa acgtagtgga gaaaaaatca
     8221 gggctgagga tttcaaacca gcaggaaata gttttgccat tccggtgtca gatccagtgt
     8281 cagatcaaga tttaggagtg atttacatct ccttggatcc tgctgtttta taccatgcca
     8341 ttgataatac tagaggtcat actccgatgg cagtaacagt gacctcacct tttgatacgg
     8401 agatttttca tattggtgag acagttgata aggagagtga aaattggcta gttggcttaa
     8461 cttctcatgg atatcaggtt caggtggcag ttcctaaaaa ctttgtttta caaggaacag
     8521 tgactagctc tgctttgatt gtgggtttga gccttctctt tattgtcatt ctttatctga
     8581 ctttgaggca gacttttgct aattaccaaa agcaggtagt ggatttagta gaatccattc
     8641 aagtcattgc tcaaggcgaa gaggggcgtc ggattgacat ttccgagaaa gatcaggaat
     8701 tactcctaat cgcggagacg accaatgata tgttggatcg attggaaaag aatatccatg
     8761 atatttacca gttagagctt agtcaaaaag atgccaatat gcgagccttg caggcgcaaa
     8821 tcaatcctca ttttatgtat aatacgctgg agttcttgcg catgtatgca gttatgcaga
     8881 gtcaagatga gttggcagat atcatttatg aattcagtag tctcttgcgt aacaatattt
     8941 ccgacgaaag agagaccctc ctcaaacagg aattagaatt ttgccgtaaa tacagctatc
     9001 tctgcatggt tcgctatccc aagtccattg cctatggttt caagatagat ccagagttag
     9061 agaatatgaa gattcccaag tttaccttgc aaccgctggt agaaaactat ttcgcgcatg
     9121 gtgttgacca caggcggaca gataatgtga ttagcatcaa ggctcttaaa caggatggtt
     9181 ttgtggaaat tttggtggtc gataatggta gaggaatgtc ggctgaaaag ttggcaaata
     9241 tccgagaaaa attaagtcag agatattttg aacaccaagc cagctacagt gatcaaaggc
     9301 agtctatcgg gattgtcaat gtacacgagc gttttgtgct ctattttgga gaccgctatg
     9361 ccattacgat agagtctgca gagcaagccg gtgttcagta tcgtattaca attcaagatg
     9421 agtagaaagg gagaaaatgt ataaagtatt attagtagat gatgagtaca tggtgacaga
     9481 aggtctgaag cgtttgattc cctttgataa gtgggatatg gaggtcgtcg caacagccag
     9541 tcatgccgat gaagctctag aatatgttca ggaaaatcct gtcgatgtca tcatttccga
     9601 tgtcaatatg ccagacaaaa cagggcttga tatgattcgg gagatgaaag agatcttacc
     9661 agatgctgcc tatatcctgc tctcaggtta tcaggagttt gattatgtaa aaagagcaat
     9721 gaaccttagt gtggtggact atttggtcaa gcctgttgat aaggtagagc tgggaaatct
     9781 gctggagaag attgcaggtc agctcggcga gagagggaag aaaagtcaga ctcttagtca
     9841 agaattagac gaggctggat ttgttagtta tttaggggat aaggagaatt ggtggatagg
     9901 tctatccaag gaaaaacaag gttccttcgc cattccctac tatgtcttgg gccaagactg
     9961 gcagattttc atttctgacc aacccctaga tggtttagtc gttacacctt ttgaagctcc
    10021 ttatcaagaa cactttgaac gctggaagct gaatgctgag aaaaccctct tttacggttc
    10081 tgtaaatctg cagcagtctg agagtctctt tgcctattac gaaccgattt atagggttat
    10141 cattcaggga aatctcaatc aaatcgtaga agagttaaat ctcttggaga aggtagttct
    10201 tgaaaatacg ccgcgtgttc cgattactaa acagcttttt attcagtttg tcatggatgt
    10261 tttccattta tttgaacatc tcaaagctga tgacctgaca gacatcgtca aaaccattca
    10321 tgctattcaa tccttcgatg aattggttcc ttatatcaag gaaactctga ccagcttttt
    10381 cggtcaatac cgtatgaatg aaaatgtggt cagtgtgctg gaagtcattg gtcgtgatta
    10441 ccaaaaagag ctttccctca aggatatcag taaggctctc tttatcaatc ctgtctatct
    10501 agggcagttg attaagcgtg aaaccgattc gacttttgca gagttactaa acaaacaacg
    10561 tattaaggct gcccaacaac ttttgctttc aactagtgac agcatcgaag atatttgtta
    10621 tgctgttggt tacagtaacc ttggatattt ctataaagtt tttcgaaaat tgtgcggaaa
    10681 atcgccaaaa gcctaccgaa aacaggtaga aactatacta taagatttgt attcctttac
    10741 aaaaggtgct ataatattat caggaggttc tatcatgaaa aagaaaccaa tttatctatg
    10801 ggtcttgcta atcttgtctg cccttatttc agttccgtct ctgtttggaa ttgtgagtcc
    10861 cttgcctagt aaagaagccc ttcgtgctgc tcagaaacaa gttgcagggg tcaatgctca
    10921 gcaattagaa gaccagctta attataccta tagagtagca gaagcatctc attctatttt
    10981 taatgttgct ttgattgtgc tatctactat tttagtggtc gtagcgattg tcttccttgt
    11041 tcgtaaaaat ttgcaatatg caaactatac ttacgttggt tatgttttgt tagctattat
    11101 tggttcgatt tatggctatg ttggtttaca agacgctgtg cagttggttc aagatgagag
    11161 catgcgtttg acagtgagta ttggttcaaa agctgttagc attttctata tcgtcatcaa
    11221 tgttctcttc ctagcccttg tcttctataa gatgtggcga caacagaaag ccttggcaga
    11281 agaagaggaa acagaagagc ttacctaagt attgacaaaa aagaactatc aagatacaat
    11341 cttggtagtt gttttttgat tatagataaa atcatggagg tacatatgaa gacaatttct
    11401 ttagtttata ttagtttgag tggcaacact gaaagttttg tgacgcgctt gaaagactat
    11461 ctcttgtccc agtacaaagg gattgaggtt caaaagattc atatcaagga tttagtcaag
    11521 gaaggcaaaa atttctatga aatggaccat ccctatgtcg cttttttgcc gacctatctc
    11581 gaaggtggga atggcgtgga taacggagat gttgagattt tgacgacacc ggtgggagat
    11641 tttattgcct atggtaacaa tgctagtaag tgttttggtg tggttgggtc aggaaatcgt
    11701 aactttaata accaatactg cctaacagcc aagcaataca gtcaacgctt tggcttccct
    11761 gtattggctg actttgaaat gcgaggcatg ctggaagata tcaaacatgt cgcagctatt
    11821 atcgcagatt tgtatgagtt ggaaaaggag aattaatact caatgaaaat caaagagcaa
    11881 actaggaagc tagtcgcagg ttactcaaag cacagctttg aggttgcaga tagagctgac
    11941 gtggtttgaa gagattctcg aatagtataa agttcttata agaggtggtt gaagttgttc
    12001 aactgttttt tgagtataaa cagtctttaa gaacgtaaaa aagcataagt tcaggtcttc
    12061 aaaaccttgt tcttatgctt tttatcatag aaatatttgc tgaattttct cttgaaatga
    12121 aaccttatct tcatctcgcg cttgtccctt accctgcttt tccgattgcg agtgcgtaga
    12181 taaagaagat ggcgaagcca aagaggaaaa tcaatcccgc aatggcaagg tgtttgagcc
    12241 aagaaggaag atttttgttt tcacgcgtta ccaaggcgta attcaaaaga gcaaagaaag
    12301 gtgttgtcag gaaagagcca atcatggcaa agcggagcat ggttgaaacc tgaccagcga
    12361 agaacttgat aatgacgata ccgatgatag cagtgatggt catccagatg ttcaaagatt
    12421 tacgattgtc ctctttttga ctgattagca gtcggagaga ttcctgatta acgcgagaat
    12481 agccatcgat aacagttata actgttccaa agatacagag gaaggcaata aaggtaatca
    12541 agtaacggga ccattcgcca agaacagagg catacatacc cacgaattga gagatgtatt
    12601 tggctgaagc agcttcaacc gcctgccctg taggatactg aatcagtgct cccagtgcca
    12661 caaagaagac ggctaggata gctgttccaa tataaccagt gttaaagtca aacagagcgt
    12721 cttctgtgtt aaagttgacg gtctttctct tttcagctga ccaaagtgaa ttgatagctg
    12781 aaatttcaat aggagccggc atccatccta ggagggagac gatgaagggc agagctgcca
    12841 tttgccaagg tgtcttctcg acaaaatcag aactgtattc tggatgcttg accgccgcaa
    12901 tgataactgc aagaacagtc gcaatggtta aggcagacat aatccatttg accatgccgt
    12961 ctaaaagttt gtagcctcca aagagtagca tagcccaaat gattgcaacg agaatgaggg
    13021 accactgagt aatgctaagt ccaatcattg ggaaggcact ggcgatgata gctgagcaca
    13081 gaatggcaac accagccgtg ttgaccatag ccgaaaagac attgaggata aagaaaatcc
    13141 agagatagag ttttcctttt tcggcataac cttcaaccaa agtctttcca gtatcagctg
    13201 tgtattcagc accaaaacgg aaaaatggat atttaaagac attggctaag atgaccaaga
    13261 gaagtagaga ccaaccgtaa gaaccgccag cttgagttga ggatacaatg tgggaacctc
    13321 caacagcggc agttgccatt aggattccag gtcccattgc ttttagcttg cttgcccagg
    13381 ttgattgatt taaggaaata gcttgcgaca tgataaatac tcctttttga attttcagaa
    13441 taatctgtat atgtaatcta tattctacaa aaaattttgg aaaaatgcaa gagtattttg
    13501 aaaaaagata gaaaatttac aaagaagatc tga
//
LOCUS       DBEJHE010000044        12970 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC4 isolate 671759
            SAMN38261586-rid24793303.denovo.44, whole genome shotgun sequence.
ACCESSION   DBEJHE010000044 DBEJHE010000000
VERSION     DBEJHE010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261586
            Sequence Read Archive: SRR26833752
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 12970)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12970)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576136.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576136.1
            Genome Coverage       :: 109x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 19:48:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,067
            CDSs (total)                      :: 2,029
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 131
            CDSs (without protein)            :: 131
            Pseudo Genes (ambiguous residues) :: 0 of 131
            Pseudo Genes (frameshifted)       :: 64 of 131
            Pseudo Genes (incomplete)         :: 59 of 131
            Pseudo Genes (internal stop)      :: 46 of 131
            Pseudo Genes (multiple problems)  :: 32 of 131
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12970
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261586-rid24793303.denovo.44"
                     /strain="GPSC4"
                     /isolate="671759"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            53..415
                     /locus_tag="ACL3EZ_001841"
     CDS             53..415
                     /locus_tag="ACL3EZ_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-export chaperone SecB"
                     /protein_id="HGR0393367.1"
                     /translation="MLEVGLNFLISLFTFTFDILYPIVKVGHTDDYSHGAVKLSVSLV
                     DKDAMKKISVTVIGYFEINIDENITDILYVNGTAILYPYLRSIVSIVSAIDSSEAMLL
                     PTINVLELLDKSQPFEEE"
     gene            814..1059
                     /locus_tag="ACL3EZ_001842"
     CDS             814..1059
                     /locus_tag="ACL3EZ_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0393368.1"
                     /translation="MKAFYITIEKFIRDDESLKCYFTKVISSRSKVTSLDQIEADKTI
                     QRKYSSELKKFIGFYNEIICEENSFLHVRKRWSSWFR"
     gene            1460..2452
                     /locus_tag="ACL3EZ_001843"
     CDS             1460..2452
                     /locus_tag="ACL3EZ_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGR0393369.1"
                     /translation="MAMIEVEHLQKHFVKIVKEPGLKGALRSFIHPEKQTFEAVKDLT
                     FEVPKGQILGFIGANGAGKSTTIKMLTGILKPTSGFCRINGKIPQDNRQDYVKDIGVV
                     FGQRTQLWWDLALQETYTVLKEIYDVPNSLFHKRMDFLNEVLDLKDFIKDPVRTLSLG
                     QRMRADIAASLLHNPKVLFLDEPTIGLDVSVKDNIRRAITQINQEEETTILLTTHDLS
                     DIEQLCDRIFMIDKGQKIFDGTVSQLKETFGKMKTLSFELLPGQSHLVSHYEGLSDMT
                     IDRQGNSLNIEFDSSRYQSADIIKQTLSDFEIRDLKMVDTDIEDIIRRFYRKEL"
     gene            2454..3272
                     /locus_tag="ACL3EZ_001844"
     CDS             2454..3272
                     /locus_tag="ACL3EZ_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0393370.1"
                     /translation="MIKLWRRYKPFINAGVQELITYRVNFILYRIGDVMGAFVAFYLW
                     KAVFDSSQESLIQGFSMADITLYIIMSFVTNLLTRSDSSFMIGEEVKDGSIIMRLLRP
                     VHFAASYLFTELGSKWLIFISVGLPFLSVIVLMKIISGQGIVEVLGLTVLYLFSLTLA
                     YLINFFFNICFGFSAFVFKNLWGSNLLKTSIVAFMSGSLIPLAFFPKVVSDILSFLPF
                     SSLIYTPVMIIVGKYDASQILQALLLQFFWLLVMVGLSQLIWKRVQSFITIQGG"
     gene            3274..4059
                     /locus_tag="ACL3EZ_001845"
     CDS             3274..4059
                     /locus_tag="ACL3EZ_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0393371.1"
                     /translation="MKKYQRMHLIFIRQYIKQIMEYKVDFVVGVLGVFLTQGLNLLFL
                     NVIFQHIPFLEGWTFQEIAFIYGFSLIPKGMDHLFFDNLWALGQRLVRKGEFDKYLTR
                     PINPLFHILVETFQIDALGELLVGGILLGTTVTSIVWTLPKFLLFLVCIPFATLIYTS
                     LKIATASIAFWTKQSGAMIYIFYMFNDFAKYPISIYNSLLRWLISFIVPFAFTAYYPA
                     SYFLQEKDVFFNVGGLMLISLVFFVISLKLWDKGLDSYESAGS"
     gene            4098..4376
                     /locus_tag="ACL3EZ_001846"
     CDS             4098..4376
                     /locus_tag="ACL3EZ_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family acetyltransferase"
                     /protein_id="HGR0393372.1"
                     /translation="MFVIEEVKDENQKKAVVAEVLKDLPEWFGIPESTQAYIEGTTTL
                     QVWTAYQESDLTRFVSLSYSSEDCAEIDCLGVKKLIKVEKLGANCLLL"
     gene            4361..4558
                     /locus_tag="ACL3EZ_001847"
     CDS             4361..4558
                     /locus_tag="ACL3EZ_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR0393373.1"
                     /translation="MLATLESEARKKVGYLQVKTVAEGSNKDYDRTNDFYRGLGFKKL
                     EIFPQLWNPQNPCQILIKKLE"
     gene            5290..11712
                     /locus_tag="ACL3EZ_001848"
     CDS             5290..11712
                     /locus_tag="ACL3EZ_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HGR0393374.1"
                     /translation="MKKSTVLSLTTAAVILAAYAPNEVVLADTSSSEDALSISDKEKV
                     AENKEKHKDIHNAIETSKDTEEKKTTIIEEKEVVSKNPVIDTKTSNEEAKIKEENSNK
                     SQGDHTDSFVNKNTENPKKEDKVVYIAEFKDKESGSKAIKELSSLKNTKVLYTYDRIF
                     NGGAIETTQDNLNKIKQIEGITSVERAQKVQPMMNHARKEIGVEEAIDYLKSINAPFG
                     KNFDGRGMVISNIDTGTDYRHKAMRIDDDAKASMRFKKEDLKGTDKNYWLSDKIPHAF
                     NYYNGGKITVEKYDDGRDYFDPHGMHIAGILAGNDTEQDIKNFNGIDGIAPNAQIFSY
                     KMYSDAGSGFAGDETMFHAIEDSIKHNVDVVSVSSGFTGTGLVGEKYWQAIRALRKAG
                     IPMVVATGNYATSASSSSWDLVANNHLKMTDTGNVTRTAAHEDAIAVASAKNQTVEFD
                     KVNIGGESFKYRNIGAFFDKNKITTNEDGTKAPSKLKFVYIGKGQDQDLIGLDLRGKI
                     AVMDRIYTKDLKNAFKKAMDKGARAIMVVNTVNYYNRDNWTELPAMGYEADEGTKSQV
                     FSISGDDGVKLWNMINPNKKTEVKRNNKEDFKDKLEQYYPIDMESFNSNKPNVGDEKE
                     IDFKFAPDTDKELYKEDIIVPAGSTSWGPRIDLLLKPDVSAPGKNIKSTLNVINGKST
                     YGYMSGTSMATPIVAASTVLIRPKLKEMLERPVLKNLKGDDKIDLTSLTKIALQNTAR
                     PMMDATSWKEKSQYFASPRQQGAGLINVANALRNEVVATFKNTDSKGLVNSYGSISLK
                     EIKGDKKYFTIKLHNTSNRPLTFKVSASAITTDSLTDRLKLDETYKDEKSPDGKQIVP
                     EIHPEKVKGANITFEHDTFTIGANSSFDLNAVINVGEAKNKNKFVESFIHFESVEEME
                     ALNSNGKKINFQPSLSMPLMGFAGNWNHEPILDKWAWEEGSRSKTLGGYDDDGKPKIP
                     GTLNKGIGGEHGIDKFNPAGVIQNRKDKNTTSLDQNPELFAFNNQGINAPSSSGSKIA
                     NIYPLDSNGNPQDAQLERGLTPSPLVLRSAEEGLISIVNTNKEGENQRDLKVISREHF
                     IRGILNSKSNDAKGIKSSKLKVWGDLKWDGLIYNPRGREENAPESKDNQDPATKIRGQ
                     FEPIAEGQYFYKFKYRLTKDYPWQVSYIPVKIDNTAPKIVSVDFSNPEKIKLITKDTY
                     HKVKDQYKNETLFARDQKEHPEKFDEIANEVWYAGAALVNEDGEVEKNLEVTYAGEGQ
                     GRNRKLDKDGNTIYEIKGAGDLRGKIIEVIALDGSSNFTKIHRIKFANQADEKGMISY
                     YLVDPDQDSSKYQKLGEIAESKFKNLGNGKEGSLKKDTTGVEHHHQENEESIKEKSSF
                     TIDRNISTIRDFENKDLKKLIKKKFREVDDFTSETGKRIEEYDYKYDDKGNIIAYDDG
                     SALQYETEKLDEIKSKIYGVLSPSKDGHFEILGKISNVSKNAKVYYGNSYKSIEIKAT
                     KYDSHSKTMTFDLYANINDIVDGLAFAGDMRFFVKDDNRIKAETKIRMPEKNKETKAE
                     YPYVSSYGNVIELGEGDLSKNKPDNLTKMESGKIYSDSEKQQYLLKDNIILRKGYALK
                     VTTYNPGKTDMLEGNGVYSKEDIAKIQKANPNLRVLSETTIYADSRNVEDGRSTQAVL
                     MSALDGFNIIRYQVFTFKMNDKGEAIDKDGNLVTDSSKLVLFGKDDKEYTGEDKSNVE
                     AIKEDGSMLFIDTKPVNLSMDKNYFNPSKSNKIYVRNPEFYLRGKISDKGGFNWELRV
                     NESVVDNYLIYGDLHIDNTRDFNIKLNVKDGDIMDWGMKDYKANGFPDKVTDMDGNVY
                     LQTGYSDLNAKAVGVHYQFLYDNVKPEVNIDPKGNTSIEYADGKSVVFNINDKRNNGF
                     DGEIQEQHIYVNGKEYTSFDDIKQITDKTLNIKIVVKDFARNTTVKEFILNKDTGEVS
                     ELKPHRVTVTIQNGKEMSSTIVSEEDFILPVYKGELEKGYQFDGWEISGFEGKKDAGY
                     VINLSKDTFIKPVFKKIEEKKEEENKPTFDVSKKKDNPQVNHSQLNESHRKEDLQRED
                     HSQKSDSTKDVTATVLDKNNISSKSTTNNPNKLPKTGTASGAQTLLAAGIMFIVGIFL
                     GLKKKNQD"
     gene            12344..12820
                     /locus_tag="ACL3EZ_001849"
     CDS             12344..12820
                     /locus_tag="ACL3EZ_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGR0393375.1"
                     /translation="MVLDYFFDKNLVFCLEADNQEHLFDQVATLLEEREIVTPTYREA
                     LITREKSFPTGLDMEFLGKDLPNVAIPHTDIVHNLAEKVVVVRLEKPVTFHNMIAPDK
                     EVEVSLLFFIINNSSSSQTNILAQLMDFFTGNGHLEDLSKISEPEKLYAYIAEATA"
     gene            12858..>12970
                     /locus_tag="ACL3EZ_001850"
     CDS             12858..>12970
                     /locus_tag="ACL3EZ_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HGR0393376.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHCDAV"
BASE COUNT         4525 a         1935 c         2559 g         3951 t
ORIGIN      
        1 acctgcggct agtttcctag tttgctcttt ggttttcatt gagtataaca cattgttaga
       61 agttggttta aatttcctaa tcagtttgtt cacatttacc ttcgatatat tatatcccat
      121 agttaaggtt ggtcatacag atgattatag ccatggagcc gtaaaactta gtgtttcttt
      181 agttgacaaa gatgccatga aaaaaatatc tgtaactgta ataggatatt ttgaaataaa
      241 tatagatgaa aatatcaccg atattctata cgtaaatggt actgctattc tttatcctta
      301 tttacgttct attgtttcaa tagtttcggc aattgatagc agtgaagcaa tgttgctacc
      361 taccattaat gttttagagt tactagataa atctcaacct tttgaagaag aataatttat
      421 tagctcacta aattgagggt aaggaaaagt aaaagcagta agaaaaatgt cttgcattat
      481 acagcaactt tttgggaatg agtagatgga ttgaataaaa tttgattaag agtggatgat
      541 ttatctgtag attattattg gacagttagt cttgaagtag tctaagaatt aggttataat
      601 cagtagaagc cttgctaata atgaggaggt tagtttatgt atagtagact gaatctaaaa
      661 tagtacgaaa caattgctaa aacatttata gaaattaatt ttactttccc aatcgatttg
      721 ttctcatctt atttcaatcc gctatatatt atggtatcga atcttcatca gaatgataaa
      781 attaatcaat taatatctga ttacaaacag aatatgaaag ctttttatat cactattgaa
      841 aaatttatac gagatgatga aagccttaag tgttatttta caaaggttat ttcaagtcgt
      901 tccaaggtaa caagtctaga tcagattgaa gctgataaaa cgatacaaag aaaatattca
      961 agtgagctaa aaaaatttat tggattttat aatgagatta tttgtgagga aaatagtttc
     1021 ctacatgtac gaaagaggtg gtcgagttgg tttaggtagt cggtgcgtga gttgataatt
     1081 ctcagggtat ggacttcttt ttcatgaatg aggtaaaaga gcaggtattg tttagagaca
     1141 atcattctga gcatattttc tggatagagg gagtatccga ttttatgatc aaagttaata
     1201 ccgccctctg gtgagaagat gagtaggttg gtaatttaaa ctattaaaca gaatttttga
     1261 ttaaaagtat tatttcatga gagaaatcct aatttcacaa tctataggca aacgcttgca
     1321 tttcgttttt tattggacta taataggttg gtataaagcc ttctgtagta ataaaatgta
     1381 gaaggtgtag aaagtaagga tttagaatat ttgtagttaa aaacacaatg ttgctattcc
     1441 ttacgatagg gagatagata tggcaatgat agaagtggaa catcttcaga aacattttgt
     1501 gaagattgtt aaggaaccgg gcttgaaggg ggctttgcgc tcctttattc atcctgaaaa
     1561 gcagaccttt gaagcggtca aggatttgac ctttgaggtt ccaaaagggc agattttagg
     1621 atttatcggg gcaaatggtg ctgggaagtc gacaaccatt aaaatgctga caggaatttt
     1681 gaaaccaaca tctggttttt gtcggattaa cggcaagatt ccccaggaca atcggcaaga
     1741 ttatgtcaaa gatattggcg tagtctttgg acaacgcacc cagctatggt gggatttggc
     1801 tctgcaagag acctacactg tcttaaaaga gatttatgat gtgccaaact cgctctttca
     1861 taagcgtatg gactttttga atgaagtctt ggatttgaag gactttatca aggatcccgt
     1921 gcggactctt tcactgggac aacggatgcg agcggatatt gcggcctcct tgctccacaa
     1981 tcccaaggtt ctttttttag atgagccgac cattggtttg gacgtttcgg ttaaggataa
     2041 tattcgtcgg gcaattactc agatcaatca agaggaagaa actaccattc ttttgaccac
     2101 tcacgatttg agtgatattg agcaactttg tgatcggatt ttcatgattg acaaggggca
     2161 aaagattttt gatggaacgg tgagccaact caaggagacc tttggtaaga tgaagactct
     2221 ctcttttgaa ctgctaccag gtcaaagtca tctcgtctct cactatgaag gtctgtctga
     2281 tatgaccatt gatagacaag gaaacagcct caacattgaa tttgatagtt ctcgctacca
     2341 gtcagctgac attatcaagc aaaccctatc tgattttgaa atccgcgatt tgaagatggt
     2401 ggatacggat attgaggata ttatccgtcg cttctaccga aaggagctct aggatgatca
     2461 aattgtggag acgttataaa ccctttatca atgcaggggt tcaggagttg attacttacc
     2521 gagtcaactt tattctctat cggattggcg atgtcatggg ggcttttgtg gccttttatc
     2581 tctggaaggc tgtctttgat tcttcgcaag agtctttgat tcagggcttc agtatggcgg
     2641 atatcaccct ctacatcatc atgagttttg tgaccaatct tctgactaga tccgattcgt
     2701 cctttatgat tggggaggag gtcaaggatg gctccattat catgcgtttg ttgcgaccag
     2761 tgcattttgc ggcctcctat cttttcaccg agcttggttc caagtggttg atttttatca
     2821 gcgttggcct tccattttta agtgtcattg tcttgatgaa aatcatatcg ggtcaaggta
     2881 ttgtagaggt gctaggatta actgtccttt atctttttag cttaacgctc gcctatctga
     2941 ttaacttttt ctttaatatt tgctttggat tttcagcctt tgtgtttaaa aatctttggg
     3001 gttccaacct acttaagact tccatagtgg cttttatgtc ggggagtttg attcccttgg
     3061 cattctttcc aaaggttgtt tcagatattc tctccttttt gcctttttcg tccttgattt
     3121 atactccagt tatgatcatt gttggaaaat acgatgccag tcagattctt caggcactcc
     3181 ttttgcagtt cttctggctc ttagtgatgg tgggattgtc tcagttaatt tggaaacggg
     3241 tccagtcctt tatcaccatt caaggaggtt agtatgaaaa aatatcaacg aatgcatctg
     3301 atttttatca gacaatacat caaacaaatc atggaatata aggtagattt tgtggttggt
     3361 gtcttgggag tctttctgac tcaaggcttg aatctcttgt ttctcaatgt catctttcaa
     3421 catattccat tcctagaagg ctggaccttt caagagatag ctttcattta tggattttcc
     3481 ttgattccca agggaatgga ccatctcttt tttgacaatc tctgggcact agggcaacgc
     3541 ctagtccgaa aaggggagtt tgacaagtat ctgactcgtc ccatcaatcc tctctttcac
     3601 atcctagttg aaacctttca gattgatgcc ttgggtgaac tcttagtcgg tggtatttta
     3661 ttgggaacaa cagtgaccag cattgtttgg actcttccaa aattcctgct tttcctagtt
     3721 tgtattcctt ttgcgacctt gatttatact tctcttaaaa tcgcaacagc cagtatcgcc
     3781 ttttggacta agcagtcagg cgccatgatt tacatcttct atatgttcaa tgactttgct
     3841 aagtatccga tttctattta caattctctt cttcgttggt tgattagctt tatcgtgcct
     3901 ttcgccttta cagcctacta tccagctagc tatttcttac aggaaaagga tgtgttcttt
     3961 aacgtaggag gtttgatgtt gatttctctg gttttctttg ttatttccct taaactttgg
     4021 gataagggct tagattccta cgaaagtgcg ggttcgtaaa agctaaagta agactaaaat
     4081 caagaaagaa acttatgatg tttgtaattg aagaagtcaa ggatgaaaat caaaaaaagg
     4141 cagttgtcgc tgaggttttg aaggatttgc cagaatggtt tggaatccca gaaagcacac
     4201 aagcctatat agaaggaacc acgacactgc aagtttggac cgcctatcag gagagtgatt
     4261 tgactagatt tgtaagctta tcctattcga gtgaagattg tgcagagatt gattgtctcg
     4321 gcgtaaaaaa gcttatcaag gtagaaaaat tgggagccaa ttgcttgcta ctttagagag
     4381 tgaagctcgt aaaaaagttg gttatctgca ggtcaaaaca gtggcagaag gttctaataa
     4441 agattatgat cgaacaaatg acttttatcg aggtcttggc tttaaaaagt tagagatttt
     4501 tcctcaacta tggaatccgc aaaatccttg tcagattttg attaaaaagc ttgaataata
     4561 ttacttgaca tctattctca gagtgctata ctgtaagtgt aatcgccgat ttagcttagt
     4621 tggtagagca aggcactcgt aaagcctagg ttataggtag ataaacgact gaggatttga
     4681 aaaaatagat aggtagaaga taaccgttaa gccttactct tagcggttat ttatattgtt
     4741 taatagcgct aatattttat caattatgcc tgttttcgtg tttctggtag ttgttcaagt
     4801 ttattgctac tatttttgat ggtatgaatg tgcttataat gtatcccggt taacgaaagt
     4861 tttggactta tactcttcga aaatctcttc aaaccacgtc aacgtcgcct tgccgtgcgt
     4921 atggttactg acttcgtcag ttctatccac aacctcaaaa cagtgttttg agctgactac
     4981 gtcagttcca tctacaacct caaaacactg ttttgagcaa tctgcggcta gtttcctagt
     5041 ttgctctttg attttcattg agtactaatc ttatttttta atgtgtgcta aaaaataaat
     5101 taactaatgt taattttttt gacttaaatt tttttaaatg atatactgtt tttatagaga
     5161 gataacaatt atatataaat gtactactct atttcctaga taatacttag taaaactttt
     5221 tataacaaag gctagcaaag ttaaagttta ttatctattg gaagttatat aaatatgtaa
     5281 ggaattaaaa tgaaaaaaag tacagtattg tcattaacca cagctgcagt tattttagca
     5341 gcctatgccc ctaatgaggt agtcttagca gacacatcta gctctgaaga tgctttaagc
     5401 atctctgata aagaaaaagt agcagaaaat aaagagaaac ataaagatat tcataatgct
     5461 atagaaactt caaaggatac tgaagaaaag aaaacaacaa ttattgagga aaaagaagtt
     5521 gttagtaaaa atcctgtgat agacactaaa actagcaatg aagaagcaaa aatcaaagaa
     5581 gaaaattcca ataaatccca aggagatcat acggactcat ttgtgaataa aaacacagaa
     5641 aatcccaaaa aagaagataa agttgtctat attgctgaat ttaaagataa ggaatctgga
     5701 tcaaaagcaa tcaaggaact atccagtctt aagaatacaa aagttttata tacttatgat
     5761 agaattttta acggtggtgc tattgaaaca actcaagata atctgaataa aattaaacaa
     5821 atagaaggta ttacatcggt tgaaagggca caaaaagtcc aacccatgat gaatcatgcc
     5881 agaaaggaaa ttggagttga ggaagctatt gattacctaa agtctatcaa tgctccgttt
     5941 gggaaaaatt ttgatggtag aggtatggtc atttcaaata tcgatactgg aacagattat
     6001 agacataagg ctatgagaat cgatgatgat gccaaagcct caatgagatt taaaaaagaa
     6061 gacttaaaag gaactgataa aaattattgg ttgagtgata aaatccctca tgcgttcaat
     6121 tattataatg gtggcaaaat cactgtagaa aaatatgatg atggaaggga ttattttgac
     6181 ccacatggga tgcatattgc agggattctt gctggaaatg atactgaaca agatatcaaa
     6241 aactttaacg gcatagatgg aattgcacct aatgcacaaa ttttctctta caaaatgtat
     6301 tctgacgcag gatctgggtt tgcgggtgat gaaacaatgt ttcatgctat tgaagattct
     6361 atcaaacaca acgttgatgt tgtttcggta tcatctggtt ttacaggaac aggtcttgta
     6421 ggtgagaaat attggcaagc tattcgggca ttaagaaaag caggcattcc aatggttgtc
     6481 gctacgggta actatgcgac ttctgcttca agttcttcat gggatttagt agcaaataat
     6541 catctgaaaa tgaccgacac tggaaatgta acacgaactg cagcacatga ggatgcgata
     6601 gcggtcgctt ctgctaaaaa tcaaacagtt gagtttgata aagttaacat aggtggagaa
     6661 agttttaaat acagaaatat aggggccttt ttcgataaga ataaaatcac aacaaatgaa
     6721 gatggaacaa aagctcctag taaattaaaa tttgtatata taggcaaggg gcaagaccaa
     6781 gatttgatag gtttggatct taggggcaaa attgcagtaa tggatagaat ttatacaaag
     6841 gatttaaaaa atgcttttaa aaaagctatg gataagggtg cacgcgccat tatggttgta
     6901 aatactgtaa attactacaa tagagataat tggacagagc ttccagctat gggatatgaa
     6961 gcggatgaag gtactaaaag tcaagtgttt tcaatttcag gagatgatgg tgtaaagcta
     7021 tggaacatga ttaatcctaa taaaaaaact gaagtcaaaa gaaataataa agaagatttt
     7081 aaagataaat tggagcaata ctatccaatt gatatggaaa gttttaattc caacaaaccg
     7141 aatgtaggtg acgaaaaaga gattgacttt aagtttgcac ctgacacaga caaagaactc
     7201 tataaagaag atatcatcgt tccagcagga tctacatctt gggggccaag aatagattta
     7261 cttttaaaac ccgatgtttc agcacctggt aaaaatatta aatccacgct taatgttatt
     7321 aatggcaaat caacttatgg ctatatgtca ggaactagta tggcgactcc aatcgtggca
     7381 gcttctactg ttttgattag accgaaatta aaggaaatgc ttgaaagacc tgtattgaaa
     7441 aatcttaagg gagatgacaa aatagatctt acaagtctta caaaaattgc cctacaaaat
     7501 actgcgcgac ctatgatgga tgcaacttct tggaaagaaa aaagtcaata ctttgcatca
     7561 cctagacaac agggagcagg cctaattaat gtggccaatg ctttgagaaa tgaagttgta
     7621 gcaactttca aaaacacgga ttctaaaggt ttggtaaact catatggttc catttctctt
     7681 aaagaaataa aaggtgataa aaaatacttt acaatcaagc ttcacaatac atcaaacaga
     7741 cctttgactt ttaaagtttc agcatcagcg ataactacag attctctaac tgacagatta
     7801 aaacttgatg aaacatataa agatgaaaaa tctccagatg gtaagcaaat tgttccagaa
     7861 attcacccag aaaaagtcaa aggagcaaat atcacatttg agcatgatac tttcactata
     7921 ggcgcaaatt ctagctttga tttgaatgcg gttataaatg ttggagaggc caaaaacaaa
     7981 aataaatttg tagaatcatt tattcatttt gagtcagtgg aagaaatgga agctctaaac
     8041 tccaacggga agaaaataaa cttccaacct tctttgtcga tgcctctaat gggatttgct
     8101 gggaattgga accacgaacc aatccttgat aaatgggctt gggaagaagg gtcaagatca
     8161 aaaacactgg gaggttatga tgatgatggt aaaccgaaaa ttccaggaac cttaaataag
     8221 ggaattggtg gagaacatgg tatagataaa tttaatccag caggagttat acaaaataga
     8281 aaagataaaa atacaacatc cctggatcaa aatccagaat tatttgcttt caataaccaa
     8341 gggatcaacg ctccatcatc aagtggttct aagattgcta acatttatcc tttagattca
     8401 aatggaaatc ctcaagatgc tcaacttgaa agaggattaa caccttctcc acttgtatta
     8461 agaagtgcag aagaaggatt gatttcaata gtaaatacaa ataaagaggg agaaaatcaa
     8521 agagacttaa aagtcatttc gagagaacac tttattagag gaattttaaa ttctaaaagc
     8581 aatgatgcaa agggaatcaa atcatctaaa ctaaaagttt ggggtgactt gaagtgggat
     8641 ggactcatct ataatcctag aggtagagaa gaaaatgcac cagaaagtaa ggataatcaa
     8701 gatcctgcta ctaagataag aggtcaattt gaaccgattg cagaaggtca atatttctat
     8761 aaatttaaat atagattaac taaagattac ccatggcagg tttcctatat tcctgtaaaa
     8821 attgataaca ccgcccctaa gattgtttcg gttgattttt caaatcctga aaaaattaag
     8881 ttgattacaa aggatactta tcataaggta aaagatcagt ataagaatga aacgctattc
     8941 gcgagagatc aaaaagaaca tcctgaaaaa tttgacgaga ttgcgaacga agtttggtat
     9001 gctggcgccg ctcttgttaa tgaagatgga gaggttgaaa aaaatcttga agtaacttac
     9061 gcaggtgagg gtcaaggaag aaatagaaaa cttgataaag acggaaatac catttatgaa
     9121 attaaaggtg cgggagattt aaggggaaaa attattgaag tcattgcatt agatggttct
     9181 agcaatttca caaagattca tagaattaaa tttgctaatc aggctgatga aaaggggatg
     9241 atttcctatt atctagtaga tcctgatcaa gattcatcta aatatcaaaa gcttggcgag
     9301 attgcagaat ctaaatttaa aaatttagga aatggaaaag agggtagtct aaaaaaagat
     9361 acaactgggg tagaacatca tcatcaagaa aatgaagagt ctattaaaga aaaatctagt
     9421 tttactattg atagaaatat ttcaacaatt agagactttg aaaataaaga cttaaagaaa
     9481 ctcattaaaa agaaatttag agaagttgat gattttacaa gtgaaactgg taagagaata
     9541 gaggaatacg attataaata cgatgataag ggaaatatta ttgcttatga cgatggtagt
     9601 gccttacaat atgaaactga aaaacttgac gaaataaaat caaaaattta tggcgttcta
     9661 agcccatcta aagatggaca ctttgaaatt cttggaaaga taagcaatgt ttctaaaaat
     9721 gccaaggtat attatggaaa tagctataaa tcgatagaaa tcaaagcgac taagtatgac
     9781 tcacattcaa aaacgatgac atttgattta tacgctaata ttaatgatat tgtggatgga
     9841 ttagcttttg ctggagatat gcggtttttt gttaaagatg ataatcgaat aaaagctgaa
     9901 actaaaatta gaatgcctga aaaaaataag gaaactaaag cagaatatcc ctatgtatca
     9961 agttatggga atgtaatcga attaggagaa ggagatcttt caaagaacaa accagacaat
    10021 ttaactaaaa tggaatctgg taaaatctat tctgattcag aaaaacaaca atatctgtta
    10081 aaggataaca tcattctaag aaaaggctat gcactaaaag tgactaccta taatcctgga
    10141 aaaacggata tgttagaagg aaatggagtc tatagcaagg aagatatagc aaaaatacaa
    10201 aaggccaatc ctaatctaag agtcctttca gaaacaacaa tttatgctga tagtagaaat
    10261 gttgaagatg gaagaagtac ccaagctgta ttaatgtcgg ctttggacgg ctttaacatt
    10321 ataaggtatc aagtgtttac atttaaaatg aacgataaag gggaagctat cgataaagac
    10381 ggaaatcttg tgacagattc ttctaaactt gtattatttg gtaaggatga taaagaatac
    10441 actggagagg ataagtccaa tgtagaagct ataaaagaag atggctccat gttatttatt
    10501 gataccaaac cagtaaacct ttcaatggat aagaactact ttaatccatc taaatctaat
    10561 aaaatttatg tacgaaatcc agaattttat ttaagaggta agatttctga taagggtggt
    10621 tttaactggg aattgagagt taatgaatcg gttgtagata attatttaat ctacggagat
    10681 ttacacattg ataacactag agattttaat attaagctga atgttaaaga cggtgacatc
    10741 atggactggg gaatgaaaga ctataaagca aacggatttc cagataaggt aacagatatg
    10801 gatggaaatg tttatcttca aactggctat agcgatttga atgctaaagc agttggagtc
    10861 cactatcagt ttttatatga taatgttaaa cccgaagtaa acattgatcc taagggaaat
    10921 actagtatcg aatatgctga tggaaaatct gtagtcttta acatcaatga taaaagaaat
    10981 aatggattcg atggtgagat tcaagaacaa catatttatg taaatggaaa agaatataca
    11041 tcatttgatg atattaaaca aataacagac aagacactaa acattaagat tgttgtaaaa
    11101 gattttgcaa gaaatacaac cgtaaaagaa ttcattttaa ataaagatac gggagaggta
    11161 agtgaattaa aacctcatag ggtaactgtg accattcaaa atggaaaaga aatgagttca
    11221 acgatagtgt cggaagaaga ttttatttta cctgtttata agggtgaatt agaaaaagga
    11281 taccaatttg atggttggga aatttctggt ttcgaaggta aaaaagacgc tggctatgtt
    11341 attaatctat caaaagatac ctttataaaa cctgtattca agaaaataga ggagaaaaag
    11401 gaggaagaaa ataaacctac ttttgatgta tcgaaaaaga aagataaccc acaagtaaac
    11461 catagtcaat taaatgaaag tcacagaaaa gaggatttac aaagagaaga tcattcacaa
    11521 aaatctgatt caactaagga tgttacagct acagttcttg ataaaaacaa tatcagtagt
    11581 aaatcaacta ctaacaatcc taataagttg ccaaaaactg gaacagcaag cggagcccag
    11641 acactattag ctgccggaat aatgtttata gtaggaattt ttcttggatt gaagaaaaaa
    11701 aatcaagatt aagacaaaag ctatagaaaa aaatggttta tgtactgaga ttagatagtg
    11761 aggtgatgac atagttttgt gaaaacggcc atttataact caattattta gtttacttca
    11821 cttcactatt gatactattt ggagttatta atggacttag tttagataac taatgaattg
    11881 attgaaaggg ttagtattga caatattggt catattgatt agaaaataga gtctatcaaa
    11941 atttaaaggc taatagaggt gatgagacaa tttcaaggaa ttaagtagcg tttggttgct
    12001 taattccttt ttatttggaa ggaagttttt cgtaaccgcc caataacgaa gtctattgga
    12061 cggttacgat atgatcactg acttcgtcag tcttatctac aacctcaaaa ctgtgttttg
    12121 agcaacctgc ggctagcttc ctagtttact ctttgatttt cattgagtat tagaacagaa
    12181 aaaatgcttg gagtatttgt ttgtgtgttt atttttatat aacaaactat aaacaaaaca
    12241 aaaatataaa aaaagagaca aaaaagaaca aaaagtaatt gacaacggtt tcatatagtg
    12301 ttatacttat ggcataaagt taatggaaag aagggaaaaa cttatggtat tagattattt
    12361 ctttgacaaa aaccttgtgt tttgcttaga agcggataat caagaacatc tctttgatca
    12421 ggttgcaact ttattggaag aacgagaaat tgtaactcca acttatcgtg aagccttgat
    12481 cacgcgtgaa aagtcatttc caactggttt agatatggaa tttctaggaa aggacttgcc
    12541 aaatgtagcg attcctcaca cagatattgt tcataatcta gctgagaaag tggtggttgt
    12601 tcgattagaa aaaccagtaa cttttcacaa tatgatagct cctgataagg aagtagaagt
    12661 atctctactc ttctttatca ttaacaattc aagttcaagt caaacgaaca ttctggctca
    12721 gttgatggac tttttcacag gaaatggtca tcttgaagac ctatcaaaaa tttctgaacc
    12781 agaaaaactt tatgcttaca ttgctgaagc aaccgcttaa tcttgtctat taaaaaataa
    12841 aatcggagga aatccaaatg attaaaattc ttgctgcctg cggtgcaggt gttaactcaa
    12901 gtcaccaaat taaaagtgct ctagaagaag aactttcaaa ccgtggttat gatgttcact
    12961 gtgatgcagt
//
LOCUS       DBEJHE010000045        12776 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC4 isolate 671759
            SAMN38261586-rid24793303.denovo.45, whole genome shotgun sequence.
ACCESSION   DBEJHE010000045 DBEJHE010000000
VERSION     DBEJHE010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261586
            Sequence Read Archive: SRR26833752
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 12776)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12776)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576136.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576136.1
            Genome Coverage       :: 109x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 19:48:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,067
            CDSs (total)                      :: 2,029
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 131
            CDSs (without protein)            :: 131
            Pseudo Genes (ambiguous residues) :: 0 of 131
            Pseudo Genes (frameshifted)       :: 64 of 131
            Pseudo Genes (incomplete)         :: 59 of 131
            Pseudo Genes (internal stop)      :: 46 of 131
            Pseudo Genes (multiple problems)  :: 32 of 131
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12776
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261586-rid24793303.denovo.45"
                     /strain="GPSC4"
                     /isolate="671759"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            <1..1280
                     /locus_tag="ACL3EZ_001851"
     CDS             join(<1..370,370..1280)
                     /locus_tag="ACL3EZ_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HGR0393377.1"
                     /translation="SKRFGVDVSGLKYMVKLIDRYGIEIVKKGKNRHYSSKLKQEMMD
                     KALLEGCSQRSISLDYALPNQGMLSFWPAQYKKNGYTIVEKTRGRPAKMGRKRKKTWE
                     EMTELERLQEENERLRTEVAYPKKVKRVRGKGRSPRARKAETVREMVSGGFRLDFLLE
                     TARLARSTYYYQLKQLDGVDKDKEIKTEIQGIDNEHKGNYGYRRIHLELRNRGFVVNH
                     KKVQRLMRILGLTARIRRKRKYSSYQGEIGKKAENLIQRQFEASRPMEKCYTDVTEFA
                     IPNSTQKLYLSPVLDGFNSEIIAYHLSTSPNLEQVKSMLEQAFTEKYYENTILHSDQG
                     WQYQHDSYHRFLESKEIQASMSRKGNSPDNGMMESFFGILKSEMFYGYEKNFRSLENL
                     EQAIVDYIDYYNNKRIKVKLKGLSSVQYRTKSFG"
     gene            complement(1515..2123)
                     /locus_tag="ACL3EZ_001852"
     CDS             complement(1515..2123)
                     /locus_tag="ACL3EZ_001852"
                     /inference="COORDINATES: protein motif:HMM:NF016726.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HGR0393378.1"
                     /translation="MQIKFIDKVSNLIMLNLLYVASVVTVIAIGSGESALIATLIKIV
                     RHEESYPYRDFANSFFKDYWKNLGAALISNLPILILLFSLFFLPYIPLPIYIISILRH
                     IGVIYIILHLIATTFLIPLIGRYNNTLKNSLHNSIMLAYKHFFIAVLIRIIEIIPVLL
                     FFILQNQLLVWITLMIFILPSITKYANAFLYNFIFSKYEKLN"
     gene            2301..3059
                     /locus_tag="ACL3EZ_001853"
     CDS             2301..3059
                     /locus_tag="ACL3EZ_001853"
                     /inference="COORDINATES: protein motif:HMM:NF013539.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HGR0393379.1"
                     /translation="MADYILVRDSEIVYETSSEIVSKVKVGEGTLNRFCKKIGYSGFQ
                     ELKLKMTKDILELESQKMSSDTFIDEIKNNYLSIVESTRKLIDGRQIELAIKLIREAN
                     QILMIGVGSSGNAAREFESSLLRIGIISKTVIDTHFQLMHTALLKDNDLIIAFSLSGS
                     TKEVEETLLNAKRKNVKIISITNYSSRNIAKLSDCVLLTSKKESYLEGGSLMAKASQL
                     FIIDVICTRLSLINYEDTICKKEEIASLLSNKVE"
     gene            3776..4462
                     /locus_tag="ACL3EZ_001854"
     CDS             3776..4462
                     /locus_tag="ACL3EZ_001854"
                     /EC_number="5.1.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009385 - N-acylmannosamine-6-phosphate
                     2-epimerase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006051 - N-acetylmannosamine metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019262 - N-acetylneuraminate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HGR0393380.1"
                     /translation="METKKIKNLKGQIIVSCQALEGEPLYTPNGGVMPLLAKAAFQAG
                     AKGIRANSVRDISEIKEEVDLPIIGIIKRDYDGFEPFISATMKEIDELVSEGVDILAL
                     DCTNRSRPGYDNITDFIHDIKVKYPNQLLMADISTFEEGKVAAESGVDFVGTTLSGYT
                     PYSPKKDNPDFELVERLVKELDVPVIAEGRISTPEQARKMLDLGAYAVVVGGAITRPL
                     EIAKKFIEVV"
     gene            4463..5395
                     /locus_tag="ACL3EZ_001855"
     CDS             4463..5395
                     /locus_tag="ACL3EZ_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001071049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0393381.1"
                     /translation="MNQEILKKSKIQLTVEHIQKYWILYLMMIPATVLLILFTYGPMY
                     GIIMAFQDFTVFKGYTGSPFVGLKHFQRLFSDPLFYRLFKNTFMVGVLDFLFSFPAPL
                     IFALILNEVRKVRFKSVVQSISYLPHFIPLVVMVGIIFELFGSYGIINSLLSSLGMEP
                     ISFFTKSEWFLPLYIGSGVWKTIGWGSIIYMGALTNIDSTLYEAADMDGANRWHKMWH
                     VTLPSLRPTVVTLFILNAGGIMQVGFEKVFLMSSPATYEVSDVLSTYVYRQGILNSDF
                     SYSAAVGLFNNIVALLFVLLANKIAKKLGEEGIV"
     gene            5406..6335
                     /locus_tag="ACL3EZ_001856"
     CDS             5406..6335
                     /locus_tag="ACL3EZ_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000577774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGR0393382.1"
                     /translation="MIFSKNTKKSNRDKETFVDYLFIFILIIITLLMLYPLWWVVMTS
                     LSEPVWLSKNVVKLFPLKIDITAYKFIFGDSKLWQAYGNSVLYAALSTIVSVAVCSMY
                     AYPLTIPEIRGKKFWNTLILIPMFFSGGMIPLYIQVANLGLLNTAWALVLPGAVSTYY
                     IILFRTQFKSIPMELRESARIDGASEFRIFWNLVLPLSKVIFMIIALYCIVGSWNSFT
                     PPLLYLNDDTKMPLSIYLRNLVVTNTTDTAELSLSAGNTYYQQIAAQGGGIGMRIAIK
                     MGTIVVSVIPIMMIYPFIQKHFVKGILLGSVKG"
     gene            6349..7788
                     /locus_tag="ACL3EZ_001857"
     CDS             6349..7788
                     /locus_tag="ACL3EZ_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001178946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0393383.1"
                     /translation="MQNLKKYLLLDSGLVVGYTLENAQLKLNKLKKDTENNPLFGEEY
                     FAENPKLWEVRFDNSYPNVIYDKELKLYRCWYQTFVSDEASEETPLAERGEKEYIVKS
                     SRMTALCYAESKDGVKWEKPNLNLVKFKGSKDNNIVLMHAHGAGIMLDEQELDPKKRY
                     KLVSKLEFSPNLHYMVVVFSEDGIHFDEPIPWKKWNPAADSHNFPFRDPKTGKYAVIT
                     RTWANNVRLSAITFSDDFINWSEPKEILRGDGFEDQIYSMPVISYADIYLGFASMYHE
                     GDTLNENYDKVDLELKFSANLEQWDSVCKGDYLIERGGGVYPQNADFDASCIFTAAPI
                     IEDDKIWFYYMGGNGNHTGFRESSLARGYIKKDQFAYYTNKREGIPAKISTVSFQTYD
                     DEIYILADIPENGYIKVAVGTKYGNAYSDFGQEDISLVQVSDGKYKLEFNKKSILDLG
                     NSPVAFKFEIENAKLYGIEGSIQQHYLKY"
     gene            7857..9434
                     /locus_tag="ACL3EZ_001858"
     CDS             7857..9434
                     /locus_tag="ACL3EZ_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HGR0393384.1"
                     /translation="MVKLNKVLKGSVAFLSASLLLAACGNNANSKPAEKTADGKTKIS
                     FLSTWQINDVRPPKDETLVGQWLEEQLGIDIDLVTIPGEGVSSKVNSLITSNQLPTVL
                     LTTGDKSDIAGINKLGKQGAFLDLSQHMDKLPNYKKYLEKNNALAQIEDDEKHIYAFT
                     KFFTDENIMYTTPILRKDLLVGSEFEDLSKIKTVDDYTKVLKYLTEKQGSPAFIQRNG
                     YEGFMKRVTPLWNLSHRTYYDYESDSYKHPVEQPQLKQFVEWLKELRKDNVLHPDWAV
                     MKDETWEGLLASNKGSFTVDRMNIIGDNNFDKSFDWQPLVYPEINGKRYLQPKTPYIS
                     DSGWVINANAPKEEIDKALEFFNFLYADENQEKLAIGFEGKTFTRENPNTQAGIKWLI
                     QIYGENAGNDKAELLFKHGNQAFTRVQTKLDIEAQPGTFPKVMYDQVDKIKKDLGGFR
                     PDTPVLSFTTEELDVLTKSEAGLNTFFDENIIKFIEGQRDMSEWDSFINEAKSKDLDK
                     VTKVYNDAYKRVKDRMK"
     gene            9494..10954
                     /locus_tag="ACL3EZ_001859"
     CDS             9494..10954
                     /locus_tag="ACL3EZ_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000272432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HGR0393385.1"
                     /translation="MYDVVIIGAGSSGALAAIASGRLGLKTCLIEKGSRIGGVPINTL
                     MGSFANLYFDDSGRVNASKIVGELIERIIKKGGTVFNSMEELMNVNDFYQITIPYQPE
                     VYESVLTDMLIESKVDILLNVEVNNIIYDSKNIKSLEILSNQEVKLIDSKVFIDATGN
                     ATIASASGADVYEKNSSYGCLMRVGGVDISKTIEHIEKTKQWNYIEGYNQWLEEVLAN
                     RKYRATGAVLKDPVSYDHAPMLSKDDHFMNDEKWNYIKERWEKFRFIYTLEVSLFRNE
                     LKKAVESGDFNFEIYHDDKSGVTMNGDGISYGSWGQNVALINVAKAFGFNPKYMEDES
                     HANILSRKYNLTFLSFLKKYVPGFENSFILDQGTRATNRSCRHIDNSSMMDEILDFPM
                     YTFKTMYSYQTPKEITYKSIVGGKLNNLFVIGKGAYQSESFRSQISCMLMGISSAAAA
                     KTIIEDKSNTLNINRDLFKSNLDILFTWEFSNWITD"
     gene            10976..11431
                     /locus_tag="ACL3EZ_001860"
     CDS             10976..11431
                     /locus_tag="ACL3EZ_001860"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001000318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HGR0393386.1"
                     /translation="MNDTNKNQYFVYEFDTSFVEMSYSQFFEGYCILFSKEPYPSLSD
                     MPMEFRKEFLMEMSILGDAMLEVLNAYRINYDILGNSTPVLHAHLFPRYMWEEEERRK
                     TVVHRYDSSVFSNPEFEFTIEKHGPIIKKLRSAIDRHYREYQQLLDDSN"
     gene            11518..11646
                     /locus_tag="ACL3EZ_001861"
     CDS             11518..11646
                     /locus_tag="ACL3EZ_001861"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0393387.1"
                     /translation="MTYKVIISEVIKSMVQAYAPYSYFKVGAALETEDKNFFLDVI"
     gene            11936..12385
                     /locus_tag="ACL3EZ_001862"
     CDS             11936..12385
                     /locus_tag="ACL3EZ_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HGR0393388.1"
                     /translation="MELVEFKNGHVNTVHEHIAITKVKEFLNNHDIPKDKGGIHKIST
                     DFFYNIIDMETTTEENRPWESHKEYYDVHYLLNGEEIILYNFLSQMELSEYKVDDDWQ
                     QMNGTALFSIKLKKDMLLLLEPNDAHKTGLLVEEPINIKKVVFKVKI"
     gene            complement(12430..12776)
                     /locus_tag="ACL3EZ_001863"
                     /pseudo
     CDS             complement(12430..12776)
                     /locus_tag="ACL3EZ_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT         4537 a         1671 c         2353 g         4215 t
ORIGIN      
        1 tcaaaaagat ttggtgtgga tgtttctggt ctaaagtaca tggtgaaatt aattgaccgt
       61 tatggcatag aaatcgttaa aaaagggaag aatcgtcact attcttctaa attgaaacaa
      121 gaaatgatgg ataaagcctt actggaaggt tgttcacaaa gaagtattag tcttgattat
      181 gccctcccaa accaaggaat gctttcattt tggccggcac aatacaagaa aaacgggtat
      241 actattgttg agaaaacaag agggagacca gctaaaatgg gacgtaaacg gaagaagact
      301 tgggaagaaa tgacagaact agaacgactc caggaggaga atgaacgctt acggactgag
      361 gtggcctacc taaaaaagtt aaaagagtta gaggaaaggg acgaagccct agagcgagaa
      421 aggcagagac agttagagaa atggtttcag gaggatttcg actagatttt cttcttgaaa
      481 cagcacgttt agctcgctcg acttactatt atcagttgaa acaactggat ggggttgata
      541 aagataaaga gattaaaacc gaaattcagg gcattgataa tgaacataaa ggcaactatg
      601 gctatcgtcg aatccattta gaactaagga atcgtggttt tgtggtcaat cataagaaag
      661 ttcaacggtt gatgagaatt cttggtttaa cggctcgaat tcgccgtaaa cggaagtatt
      721 cttcctacca aggagagatt ggcaagaaag cagagaatct cattcaacgc cagttcgaag
      781 catcgaggcc aatggaaaag tgctatacag atgtgacaga gtttgccatt ccaaatagca
      841 cacagaaact ctatttatca ccagttttag atggttttaa cagtgaaatc attgcttatc
      901 atctttctac ttcgccaaac ttagaacaag tgaagagtat gttagaacag gcctttacag
      961 agaaatacta tgagaatacg attctccata gtgaccaagg ctggcaatac caacacgatt
     1021 cttatcatcg gttcctagag agtaaggaaa ttcaagcatc catgtcacgc aagggcaaca
     1081 gcccagacaa cggcatgatg gaatctttct ttggcatttt aaaatccgaa atgttttatg
     1141 gctatgagaa gaactttaga tctttagaaa accttgaaca agctattgtg gactacattg
     1201 attactacaa caacaaacga attaaggtaa aactaaaagg acttagttct gtgcagtaca
     1261 gaactaaatc ctttggataa attatttgtc taattttttg gggtcagtac agtattaaat
     1321 accatgatct tatgcgtttt ataataaaaa atctgttctt gttttatttt tagaaaattt
     1381 actaaagact aaaaatatta tgaataattt aaaaaatagt caggttatat agttttttga
     1441 aattaaaatt attttatcgt tgaaattagt taaaaatttt tataaaatca agatgcaagg
     1501 ctatgagatg ttctctagtt taatttttca tacttcgaga atataaagtt gtataaaaat
     1561 gcattagcat attttgttat tgagggaagt ataaaaatca ttaaagttat ccaaactagt
     1621 aattgattct gtaatataaa gaagagtaga actgggataa tttcaataat tctaataaga
     1681 acggcaataa aaaaatgttt ataggctaac atgattgaat tgtgtagaga attttttaaa
     1741 gtgttattat atctaccgat taaaggaatt agaaatgttg ttgctattaa atgaagtatg
     1801 atatatatta ctccaatatg tcgtaagata gaaatgatat atataggtaa tggtatgtag
     1861 ggtaggaaga acaaactgaa taataagatt aaaattggta aattagatat taatgctgct
     1921 cctaaatttt tccaataatc tttaaaaaaa ctgtttgcga agtctctata gggataggat
     1981 tcctcgtgtc gtacaatttt tattagagtt gctattaggg cactttcacc tgatccgata
     2041 gcaataactg ttactactga cgctacatag agtagattta acattataag atttgaaact
     2101 ttatcaataa attttatctg catctttaac tcctgctgtt tttatactta taatatcaca
     2161 tcatttgagt ttcatcaact ttgaatacat taagaaagaa tataactatg aggaaaggaa
     2221 aaaattatta tgaataaatc caaaaaatat aaagaaagaa ttcattatga atacgataat
     2281 cttactaaat cagagaaaaa attgctgact atattttagt tagagatagt gaaatagttt
     2341 atgaaacgtc ttcagaaatt gttagtaaag taaaagttgg agagggaact cttaatcgat
     2401 tttgcaaaaa gattggatac tctggttttc aggaattaaa attaaaaatg acgaaagata
     2461 tattagagtt agaatctcaa aaaatgagta gtgacacatt tattgatgaa ataaaaaata
     2521 attatttatc tattgtggaa agtacaagaa aattaattga tggtagacaa atagaattag
     2581 ctataaaatt aataagagaa gcaaaccaga ttttaatgat tggtgtgggt tctagtggaa
     2641 atgcggctag agaatttgag agtagtttgt taagaattgg aataataagt aagacggtaa
     2701 ttgataccca ttttcaactc atgcatactg cgttattgaa agataatgat ttgataatag
     2761 cgtttagttt atctggttcc acaaaagaag ttgaggaaac tttattaaac gcaaaaagaa
     2821 aaaatgttaa aattatttca ataacaaatt attcgtccag aaatatagca aaattatctg
     2881 actgcgttct tttgacatca aaaaaagaat cttatttaga gggtggtagt ttaatggcta
     2941 aggcttctca actattcata attgatgtaa tatgcactag actctcttta ataaattatg
     3001 aagatactat atgtaaaaaa gaagagattg cttctttgct gtcaaataaa gtggaataaa
     3061 tcaataattt ttaaatttta ataaaaattt tttaaaataa attaaaaaac gatcctaaaa
     3121 gggtcgtttt tttgctaaag ttttaaaaat aaacaataat taagattata gtgcgttgaa
     3181 tctatattag gacataacaa ttcttaaatc attgttagaa attagtttga attttccaat
     3241 caatttgttc gatttttaca tcattgcatt atatcatgtg actattaacc ttgttttctc
     3301 ctaaaattga ttttcttctt ttcttatctt gtccactcga aacaagtatt gtaagaattt
     3361 gattattttt gaaagtactt ttaatatatt tgagatagtt aaaaaagatt tgaaactaaa
     3421 ttccaaatta gaaaaagact tgaaatgcta aaaaaaaaaa gtatactcta attgaaaacg
     3481 gtaacaaaac taatttagag aatgaaatat agagtatttc tctcttaaaa gtttttggtg
     3541 aaacgagatg tagaaaggag atttagccaa agagtctatt agtgctagaa taatagatta
     3601 gaattatagt gtattgaatc tataacagta cgccttaaat gctaaaatat ttctataaat
     3661 taatttaact ttcctgatag ggctgttcat atcttatttc aattcactat ataaataaaa
     3721 ttgtagtaga tgttattgaa ttagtaaaaa aaataaaaaa acggaggttt tctgaatgga
     3781 aactaaaaaa attaaaaatt taaaaggtca aataattgtt tcctgccaag cgttagaagg
     3841 agagccactt tatactccaa atggaggagt gatgccgtta ttagcaaaag ccgcctttca
     3901 agcaggcgct aaaggtattc gtgctaattc tgtccgcgat atttcagaaa taaaagaaga
     3961 agttgactta ccaattatag gtatcataaa aagagattac gatggctttg aaccttttat
     4021 ttcagcaact atgaaagaga ttgatgaatt agttagtgaa ggagtagaca ttttagcttt
     4081 ggattgtact aatcgttcaa gaccaggtta tgataatatt actgacttta ttcatgatat
     4141 taaagtcaag tatccaaacc aattattaat ggctgatatt tctacttttg aagaagggaa
     4201 agtagctgct gaatcgggag tagattttgt gggtacgaca ttatctggtt atacaccata
     4261 tagccctaaa aaagataatc ctgattttga gttagttgaa agattggtaa aagagcttga
     4321 cgtaccagtt attgctgaag gaagaataag tactccggaa caagctagaa aaatgttaga
     4381 tttaggtgct tacgcagtgg ttgttggagg agctatcact cgtcctttgg aaatagcgaa
     4441 gaagtttatt gaggtagttt agatgaatca agaaatatta aaaaagagta agattcaatt
     4501 gacagttgaa catattcaaa aatattggat tttatattta atgatgattc cagcaactgt
     4561 tctactaatt ttatttacgt atggaccaat gtacggcatt attatggcct ttcaagactt
     4621 tactgtcttc aagggatata ctggaagtcc atttgtcggt ttaaaacatt ttcaaagatt
     4681 gttctcagat cctttgtttt atagattgtt caagaatacg ttcatggtag gggttttaga
     4741 ctttttattc tctttcccag ctccgcttat ttttgcactc atattaaacg aagtcagaaa
     4801 agtaagattt aagagtgtag ttcaatctat tagttatctt cctcatttta ttcccctagt
     4861 ggttatggtt ggtattattt ttgaactatt tggttcatat ggtattatta acagtttact
     4921 ttcatcactt ggaatggagc caataagttt ctttacaaaa tctgaatggt tcttgcctct
     4981 ctacattggt tcaggagtat ggaaaacaat aggttggggt tctatcattt atatgggagc
     5041 attaaccaat atagattcaa ctttatatga agcagcagat atggacgggg ctaatagatg
     5101 gcacaaaatg tggcatgtaa ctctaccaag tttaagacct acagtagtta ctttgtttat
     5161 actaaatgct ggtggtatca tgcaagtagg atttgaaaag gtattcttga tgtctagtcc
     5221 tgcaacatat gaagtatctg atgtattatc tacttatgtt tatagacaag gtattttaaa
     5281 ttctgatttc agttactcag ctgcagtagg attatttaat aacatagtag ctttgttatt
     5341 tgttttatta gctaataaga ttgctaaaaa acttggcgaa gaaggaattg tataaggggg
     5401 gtaaaatgat tttttcaaaa aatacaaaaa agagtaatag agacaaagaa accttcgttg
     5461 attatctctt tatattcatt ttaataataa taaccttact tatgttgtat ccattatggt
     5521 gggtagtgat gacgtcactt tcagaaccag tttggctatc taaaaacgtt gttaaattat
     5581 ttcccttaaa aatagatatt actgcatata agtttatttt tggggattct aaactatggc
     5641 aagcatatgg taatagtgta ttgtatgctg cactatctac aattgttagt gttgcggtat
     5701 gtagtatgta tgcctatcca cttacaattc ctgaaattag gggtaaaaaa ttctggaata
     5761 ctcttatttt gattccaatg ttctttagtg gaggaatgat cccgctttat atacaagttg
     5821 caaacctcgg tttattgaat actgcttggg ctcttgtttt acctggtgct gtttctacat
     5881 attatataat tttgtttaga acacagttta aatcaatccc aatggagctt cgtgagtctg
     5941 ctagaattga tggggcaagt gaatttagaa ttttttggaa tttagtatta ccattatcaa
     6001 aagttatttt catgattata gcactttatt gcatagttgg ttcatggaat agttttactc
     6061 ctccattact ttatttgaat gacgacacta agatgccttt atctatttat ttgagaaatt
     6121 tagttgttac aaatacaact gatactgctg aattatcact ttctgcaggt aatacatatt
     6181 accaacaaat tgctgctcaa ggtggaggta ttggtatgcg tattgctatt aagatgggta
     6241 ctattgttgt tagtgttatt ccaattatga tgatttatcc atttattcag aaacattttg
     6301 ttaagggaat cctgctaggt tctgtgaaag gttaataagg taattatttt gcaaaattta
     6361 aaaaaatatc ttttattaga tagcggttta gtagttgggt atacattaga aaatgctcaa
     6421 ttaaaattaa ataagctaaa aaaagatact gaaaacaatc cactatttgg tgaagagtat
     6481 tttgccgaaa atcctaaatt atgggaagtt cgttttgata attcatatcc aaacgttatc
     6541 tatgataaag aattgaaatt atatagatgt tggtatcaaa catttgttag tgatgaagca
     6601 agcgaagaga ctcctttagc agaacgtgga gagaaggaat acattgtcaa gtcatctaga
     6661 atgacagcac tttgctatgc tgaaagtaaa gatggagtaa aatgggaaaa accaaatctc
     6721 aatctagtaa aatttaaagg ttcaaaagat aataatattg ttctgatgca tgcacacggt
     6781 gcaggtatca tgctagatga acaggagttg gatcctaaga aacgatataa attagtttca
     6841 aaattagaat tttctccgaa tcttcattac atggttgttg ttttttcaga agacggtatt
     6901 cattttgacg aacctattcc atggaaaaaa tggaatcctg cagcagatag tcataatttt
     6961 ccatttagag atccaaaaac tggtaaatac gctgttatta caagaacctg ggcaaataac
     7021 gtacgtctaa gtgcaattac tttcagtgat gattttatta attggtcaga acctaaagaa
     7081 atccttaggg gagatggatt tgaagatcaa atttattcta tgccagtaat ttcatacgcg
     7141 gatatctatt taggttttgc ttcaatgtac cacgaaggcg acactttaaa tgaaaactat
     7201 gataaagtag acttagaatt gaaattctct gctaatttgg aacaatggga tagtgtatgt
     7261 aagggcgact atctcattga aaggggaggt ggagtatacc cgcagaatgc tgattttgat
     7321 gctagttgta ttttcacggc tgctccaata attgaagatg ataagatttg gttctactat
     7381 atgggtggaa atggtaatca cactggcttc cgagaaagtt cattagctag aggatatatt
     7441 aagaaagacc aatttgctta ttatactaat aagagagaag gaattccagc taaaatatct
     7501 acagttagct tccaaactta cgatgatgaa atttatatct tagctgatat tcctgaaaat
     7561 ggttatatta aagttgcggt aggtactaaa tacggtaatg cttattcaga ttttggtcag
     7621 gaagatatct ctcttgttca agtttccgat ggtaagtata agttggaatt taataaaaaa
     7681 tctatcttag atttaggtaa ttctccagtt gcgttcaaat ttgaaatcga gaatgcaaaa
     7741 ttgtatggta ttgaaggtag tattcagcaa cactatctca aatattaacc agaataattc
     7801 gttaacaaat aatctctata ttagtggaga tagatatata aaatggaggt cttattatgg
     7861 taaagcttaa taaggtatta aaagggagtg ttgcattcct gagtgcaagt ttattgctag
     7921 cagcttgtgg caataacgct aattcaaagc ccgctgaaaa aacagctgat ggtaaaacga
     7981 aaatttcgtt tctatctaca tggcaaatta atgatgttcg tccgcctaaa gatgaaacac
     8041 ttgttggtca atggttagaa gaacagctag gtattgatat tgatcttgta actattcctg
     8101 gcgagggagt aagttctaaa gtaaattctc ttattactag taaccagtta ccgactgttt
     8161 tgttgacaac aggagataag agtgatatcg ctggtatcaa caaacttggt aaacagggtg
     8221 cattcttaga tttgtcacaa cacatggaca aactaccaaa ctataagaag taccttgaaa
     8281 aaaataatgc attagctcaa atagaagatg atgaaaaaca tatttatgct ttcacaaaat
     8341 tctttactga tgagaatatc atgtatacta caccaattct gagaaaagac ttacttgttg
     8401 gttcagaatt tgaagatctt tcaaaaatta aaactgttga tgactataca aaagttttga
     8461 aatatttgac tgaaaaacaa ggttctccag catttattca acgtaatggc tatgaaggct
     8521 tcatgaagcg agttacacca ttgtggaatt taagccatcg tacatactat gactatgaat
     8581 cagattcata taaacatcca gttgaacaac ctcaattgaa acaattcgtt gaatggttga
     8641 aagaattacg taaagataac gtacttcacc ctgactgggc agttatgaaa gatgaaactt
     8701 gggaaggtct attggcttct aacaagggtt cattcactgt tgaccgtatg aatatcattg
     8761 gagataataa ctttgataaa tcatttgatt ggcagccact tgtttatcca gaaattaatg
     8821 gaaaacgtta tttgcaaccg aaaacaccgt acatttctga ttcaggttgg gtaatcaatg
     8881 ccaatgcacc aaaagaagaa attgataaag cgttagaatt ctttaatttc ttatacgctg
     8941 atgaaaatca agaaaaactt gctattggat ttgaaggtaa aacatttaca cgtgaaaacc
     9001 ctaatactca agcaggtatt aaatggttga ttcaaattta cggtgaaaat gctggaaatg
     9061 ataaagcaga actgctgttt aaacatggta accaagcatt tactcgcgtt caaactaaat
     9121 tagatattga ggcacagcca ggaacattcc ctaaagttat gtatgatcaa gtagataaaa
     9181 ttaagaaaga tttaggtggt tttagaccag atactccggt tctttccttt acaactgaag
     9241 aattagatgt tttaactaaa tctgaagcag gattaaatac tttctttgat gaaaatatta
     9301 ttaaattcat tgaaggacaa agagatatga gtgagtggga ttcatttatc aatgaagcta
     9361 aatctaaaga cttggataaa gttacaaaag tatataatga tgcctacaaa cgtgtcaaag
     9421 atagaatgaa atagactaaa tggtagctct ctggtttttc agagagctac tactgcctga
     9481 gggggagtaa gctttgtatg atgtagtaat tataggtgca ggaagttcgg gcgcattggc
     9541 tgcaattgct tcggggcgtc tagggttaaa aacttgtcta atagagaagg gaagtagaat
     9601 tggtggagtt cctattaata cactaatggg gtcatttgct aatctatatt ttgatgattc
     9661 tggtagagta aatgcaagta aaattgttgg ggaattaata gaacgtatta tcaaaaaagg
     9721 tggtactgtc tttaactcta tggaagaatt gatgaatgta aatgattttt atcagattac
     9781 aattccctat caaccagaag tttatgaatc ggttttaact gatatgttga ttgagtctaa
     9841 agttgatatt ttactaaatg ttgaagttaa taatattatt tatgatagta aaaatattaa
     9901 aagtcttgaa attttaagta atcaggaagt taaattgatt gattctaaag tttttattga
     9961 tgctacaggg aatgcaacaa ttgcttctgc tagtggagct gatgtttatg aaaaaaattc
    10021 ttcttacggt tgtttaatga gagttggagg agttgatatc tcaaagacta tagaacatat
    10081 tgaaaaaaca aagcagtgga actatataga aggatataat cagtggttag aagaagtatt
    10141 agcaaatcga aagtacagag ccactggagc agttttaaaa gatccagttt cttatgatca
    10201 tgcccctatg ctttcaaaag acgaccattt tatgaatgat gaaaaatgga attacattaa
    10261 agaaagatgg gaaaaattta gatttattta cactttagaa gtatcactat ttaggaatga
    10321 attaaaaaaa gctgtagaat ctggggattt taattttgaa atttatcatg atgataaatc
    10381 tggagtcact atgaatggcg acggtataag ctatggttca tggggtcaaa atgtagcatt
    10441 aattaatgtt gcaaaagcat ttggattcaa tcccaaatat atggaagatg aatcacatgc
    10501 taatattctt tctagaaaat ataatttaac atttttatct tttcttaaaa aatatgtacc
    10561 aggttttgaa aattctttta tccttgatca gggaactaga gctactaaca gatcatgtag
    10621 gcacattgat aattcatcta tgatggacga aattcttgat tttccaatgt atacatttaa
    10681 gactatgtat agctatcaaa ctcctaaaga aataacgtat aaatcaattg taggtggaaa
    10741 attgaataat ttgtttgtaa taggtaaagg tgcttaccaa tccgaaagtt ttagatcaca
    10801 aattagttgt atgttaatgg ggatatcatc agcagcagcg gcaaaaacta ttattgaaga
    10861 taaaagcaat actctaaaca ttaatagaga tttgtttaaa tcgaacttag atatattatt
    10921 tacatgggag ttttctaatt ggattactga ttaacaaata ataagggaat attaaatgaa
    10981 tgatactaat aaaaatcaat actttgttta tgaatttgat actagctttg tagaaatgtc
    11041 ttattctcag ttttttgaag gatattgtat tcttttttca aaagaaccct atccttcttt
    11101 atctgatatg ccaatggaat ttagaaaaga atttttaatg gaaatgagta tattaggtga
    11161 tgcgatgctt gaagtgttaa atgcctatag aattaattat gatatcttag gaaattcaac
    11221 acctgtactt catgctcatt tatttccgag atacatgtgg gaagaggaag agagaagaaa
    11281 aactgtagtt catagatatg attcttcagt ttttagcaat cctgagtttg aatttactat
    11341 agaaaagcat ggaccaatta ttaaaaaact gaggtctgct attgatagac attatagaga
    11401 gtatcaacaa ttattagatg attcaaactg aactccacat tttcgattag atttaatacc
    11461 ttgtatatta caactaggtt gtggatgata taatttttcg aaaaatatat tttaggaatg
    11521 acttataaag taattatatc agaggttatt aaatcaatgg tccaagctta tgctccttat
    11581 tcttatttta aggttggagc tgcgttagaa actgaagata aaaatttttt tctggatgta
    11641 atatagaaaa tgttgctttt ctcctacttg ctgtgcagaa cgagtatatt tttacaaagc
    11701 tgtatttaaa ggagaacgtt cgttttcaaa aatatgtatt gtaggcggaa aaaaaggtat
    11761 tttatcatct tttatagcat cttgcagggt gtcttgtcag gtaatgatag aattttgtaa
    11821 tcttgattca tttgtagtta tattggctag tgatgttgat acttataaag tatataaact
    11881 taaagaacta ctaccagtta gttttaatca agaaaattta taacaggagg gaactatgga
    11941 attagttgaa tttaaaaatg gacatgttaa tacggttcat gagcatatcg caataacgaa
    12001 agtaaaagag tttctaaata atcatgatat accaaaagat aaaggtggca tacataaaat
    12061 ttctactgat ttcttttaca atataattga tatggaaact acaactgaag aaaatagacc
    12121 gtgggaaagt cataaggaat attatgatgt ccattatctg ttaaatggag aagaaataat
    12181 tttatataat ttcttgtctc aaatggaatt gtctgaatat aaagtagatg atgattggca
    12241 acaaatgaat gggacagctt tatttagtat taaattaaag aaagatatgt tacttttgtt
    12301 ggaaccaaac gatgcacata aaacaggcct attggttgaa gaaccaatta atattaagaa
    12361 agttgttttt aaggtaaaaa tttaactgaa agtactttca gggattaaga attttaaaat
    12421 atttaatact catctgtttt caaaaagcat tctagtccat ctccgattaa cgatggactt
    12481 tatcacctct ttctccagtc cttgtatgac atcttgaagt tgattcatga catcttccaa
    12541 tatgggcatc aacagctcca taacaatagc gaaattctcg tatatagtga ctatggacat
    12601 gtggacctac tcctattgga gaccaacaag atcccagttt actgattcta ctgaaaccag
    12661 cctcatcttg gtacatcaag cgaaccttac gaaaacgtct actgatttta aagcgctttc
    12721 ttgtcttctt gaattgagat tttattttta gacgcgacaa tggtttgagc gtctgc
//
LOCUS       DBEJHE010000046        12729 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC4 isolate 671759
            SAMN38261586-rid24793303.denovo.46, whole genome shotgun sequence.
ACCESSION   DBEJHE010000046 DBEJHE010000000
VERSION     DBEJHE010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261586
            Sequence Read Archive: SRR26833752
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 12729)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12729)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576136.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576136.1
            Genome Coverage       :: 109x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 19:48:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,067
            CDSs (total)                      :: 2,029
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 131
            CDSs (without protein)            :: 131
            Pseudo Genes (ambiguous residues) :: 0 of 131
            Pseudo Genes (frameshifted)       :: 64 of 131
            Pseudo Genes (incomplete)         :: 59 of 131
            Pseudo Genes (internal stop)      :: 46 of 131
            Pseudo Genes (multiple problems)  :: 32 of 131
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12729
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261586-rid24793303.denovo.46"
                     /strain="GPSC4"
                     /isolate="671759"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(67..615)
                     /locus_tag="ACL3EZ_001864"
     CDS             complement(67..615)
                     /locus_tag="ACL3EZ_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF-type riboflavin transporter
                     substrate-binding protein"
                     /protein_id="HGR0393389.1"
                     /translation="MEIKFTIKQVVAVGIGAALFVVIGMINIPTPVPNTSIQLQYAVQ
                     ALLSIIFGPIIGLLVGLIGHAIKDSLAGYGLWWTWIIASGLFGLVVGLFRKYVRVING
                     VFDWKDILIFNLIQLLANALVWGVLAPLGDVVIYQEAAEKVFAQGIVAGIANGVSVAI
                     AGTLLLLAYAGTQTRAGSLKKD"
     gene            complement(630..1478)
                     /locus_tag="ACL3EZ_001865"
     CDS             complement(630..1478)
                     /locus_tag="ACL3EZ_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosyl-l-methionine hydroxide
                     adenosyltransferase family protein"
                     /protein_id="HGR0393390.1"
                     /translation="MNNNLLVLQSDFGLVDGAVSAMIGVALEESPTLKIHHLTHDITP
                     YNIFEGSYRLFQTVDYWPEGTTFVSVVDPGVGSKRKSVVAKTAKNQYIVTPDNGTLSF
                     IKKHVGIVAIREISEVANRRQNTEHSYTFHGRDVYAYTGAKLASGHITFEEVGPELSV
                     DQIVELPVVATIIEDHLVKGAIDILDVRFGSLWTSITREEFYKLEPEFGDRFEVTIYH
                     ADMLVYQNQVVYGKSFADVRIGQPILYINSLYRLGLAINQGSFAKAYNVGVGSSWTIE
                     IKKIEG"
     gene            1666..3015
                     /gene="trkA"
                     /locus_tag="ACL3EZ_001866"
     CDS             1666..3015
                     /gene="trkA"
                     /locus_tag="ACL3EZ_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system potassium transporter TrkA"
                     /protein_id="HGR0393391.1"
                     /translation="MKIILVGGGKVGFALCRSLVAEKHDVLLIEQDEAVLNHIVSRFD
                     IIGILGNGADFAILEQASVQDCDIFIALTEHDEVNMIAAVLAKKMGAKETIVRVRNPE
                     YSNSYFKEKNILGFSLIVNPELLAARAIANIIDFPNALSVERFAGGRVSLMEFVVKST
                     SGLCQMPISDFRKKFGNVIVCAIERDHQIIIPSGDMTVQDKDRIFVTGNRVDMILFHN
                     YFKSRAVKSLLIVGAGRIAYYLLGILKDSRIDTKVIEINPEIASFFSEKFPNLYIVQG
                     DGTAKDILLEESAQHYDAVATLTGVDEENLITSMFLDRVGVQKNITKVNRTSLLEIIN
                     APDFSSIITPKSIAVDTIMHFIRGRVNAQYSDLQAMHHLANGQIETLQFHIKEANKMT
                     AKPLSQLKLKKGVLIAAIIRKGKTIFPTGEDMLEVGDKLLVTTLLPNITKIYDLIAR"
     gene            3019..4458
                     /locus_tag="ACL3EZ_001867"
     CDS             3019..4458
                     /locus_tag="ACL3EZ_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015079 - potassium ion transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HGR0393392.1"
                     /translation="MNKSMIRYLLSKLLLIEAVLLLVPVAIAVYYRESSQVFTALFST
                     IGILVLLGGSGSLQKPKNQRIYAKEGVLIVALCWILWSFFGGLPFVFSGQIPSLIDAF
                     FEISSGFTTTGASILNDISVLSRSLLFWRSFTHLIGGMGVLVFALAIMDNAKNSHLEV
                     MKAEVPGPVFGKVVSKLKNTAQILYLLYIALFSLFVIIYYLAGMPLYDSFVIAMGTAG
                     TGGFTVYNDGIAHYGSSLITYLVSIGVLVFGVNFNLYYYLMLRRVKAFFGDEELRAYL
                     VIVLVSTGLISLNTLYLYPGFSKSFEMTFFQVSNIITTTGFGYGDITNWPLFSQFILL
                     FLMAIGGSAGSTAGGLKIIRGLILSKIAKNQILSILSPHRVLTLHVNKMVIDKDTQHK
                     ILKYFVIYAMILLALIFIVSLDSNDFLVVTSAVFSCFNNIGPILGTTSSFSIFSPISK
                     ILLSFAMIAGRLEIYPILLLFMKRTWSKR"
     gene            complement(4583..4984)
                     /locus_tag="ACL3EZ_001868"
                     /pseudo
     CDS             complement(4583..4984)
                     /locus_tag="ACL3EZ_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359733.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS alpha-glucoside transporter subunit IIB"
     gene            6384..6668
                     /locus_tag="ACL3EZ_001869"
     CDS             6384..6668
                     /locus_tag="ACL3EZ_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002923859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0393393.1"
                     /translation="MDWYDYMIQASKQSQFNASHWFRYLRKVIFEDYSYLTNQDVEKL
                     LDSKELTRFQKISLKYAFQEHTPTHKYVISLNKPAKLTNVQKLMEKYKHG"
     gene            6661..7224
                     /locus_tag="ACL3EZ_001870"
                     /pseudo
     CDS             6661..7224
                     /locus_tag="ACL3EZ_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002923862.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6036 family nucleotidyltransferase"
     gene            complement(7592..9916)
                     /gene="pflB"
                     /locus_tag="ACL3EZ_001871"
     CDS             complement(7592..9916)
                     /gene="pflB"
                     /locus_tag="ACL3EZ_001871"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008861 - formate C-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HGR0393394.1"
                     /translation="MVVKTVVEAQDIFDKAWEGFKGVDWKEKASVSRFVQANYTPYDG
                     DESFLAGPTERSLHIKKIVEETKAHYEETRFPMDTRPTSIADIPAGFIDKENEVIFGI
                     QNDELFKLNFMPKGGIRMAETTLKENGYEPDPAVHEIFTKYVTTVNDGIFRAYTSNIR
                     RARHAHTVTGLPDAYSRGRIIGVYARLALYGADYLMQEKVNDWNAIKEIDEETIRLRE
                     EVNLQYQALQQVVRLGDLYGVDVRKPAMNVKEAIQWVNIAFMAVCRVINGAATSLGRV
                     PIVLDIFAERDLARGTFTESEIQEFVDDFVMKLRTVKFARTKAYDQLYSGDPTFITTS
                     MAGMGNDGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWTDKLPYNFRRYCMHMSHKHS
                     SIQYEGVTTMAKDGYGEMSCISCCVSPLDPENEEQRHNIQYFGARVNVLKALLTGLNG
                     GYDDVHKDYKVFDIEPIRDEVLEFESVKANFEKSLDWLTDTYVDALNIIHYMTDRYNY
                     EAVQMAFLPTKQRANMGFGICGFANTVDTLSAIKYATVKPIRDEDGYIYDYETIGDYP
                     RWGEDDPRSNELAEWLIEAYTTRLRSHKLYKDAEATVSLLTITSNVAYSKQTGNSPVH
                     KGVYLNEDGSVNLSKLEFFSPGANPSNKAKGGWLQNLNSLSSLDFSYAADGISLTTQV
                     SPRALGKTRDEQVDNLVTILDGYFENGGQHVNLNVMDLNDVYEKIMSGEDVIVRISGY
                     CVNTKYLTPEQKTELTQRVFHEVLSMDDALDALS"
     gene            10265..11326
                     /gene="dinB"
                     /locus_tag="ACL3EZ_001872"
     CDS             10265..11326
                     /gene="dinB"
                     /locus_tag="ACL3EZ_001872"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HGR0393395.1"
                     /translation="MLIFPLLNDLSRKIIHIDMDAFFAAVEIRDNPKLRGKPVIIGSN
                     PRQTGGRGVVSTCSYEARAFGVHSAMSSKEAYERCPQAVFISGNYEKYKSVGLQIRAI
                     FKRYTDLIEPMSIDEAYLDVTENKLGIKSAVKIARLIQKDIWQELHLTASAGISYNKF
                     LAKMASDYQKPHGLTVILPEQAEDFLKQMDISKFHGVGKKTVERLHQMGVFTGADLLE
                     VPEVTLIDRFGRLGYDLYRKARGIHNSPVKSNRIRKSIGKEKTYGKILRAEEDIKKEL
                     TLLSEKVALNLHQQEKAGKIVILKIRYEDFSTLTKRKSLAQKTQDASQISQIALQLYE
                     ELSEKERGVRLLGITMTGF"
     gene            complement(11473..12318)
                     /locus_tag="ACL3EZ_001873"
     CDS             complement(11473..12318)
                     /locus_tag="ACL3EZ_001873"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0050380 - undecaprenyl-diphosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0016311 - dephosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HGR0393396.1"
                     /translation="MYLIEILKSIFFGIVEGITEWLPISSTGHLILAEEFIQYQNQNE
                     AFMSMFNVVIQLGAILAVMVIYFNKLNPFKPTKDKQEVRKTWRLWLKVLIATLPLLGV
                     FKFDDWFDTHFHNMVSVALMLIIYGIAFIYLEKRNKARAIEPSVTELDKLPYTTAFYI
                     GLFQVLALLPGTSRSGATIVGGLLNGTSRSVVTEFTFYLGIPVMFGASALKIFKFVKA
                     GELLSFGQLFLLLVAMGVAFAVSMVAIRFLTSYVKKHDFTLFGKYRIVLGSVLLLYSF
                     VRLFV"
     gene            12574..12729
                     /locus_tag="ACL3EZ_001874"
                     /pseudo
     CDS             12574..12729
                     /locus_tag="ACL3EZ_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844241.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         3916 a         2573 c         2381 g         3859 t
ORIGIN      
        1 ctcaaaacac tgttttgagc aacctgcggc tagcttccta gtttgctctt tgattttcat
       61 tgagtattag tcctttttca aacttcctgc acgagtttgg gttcctgcat aggcaagtaa
      121 gagaagagtt cctgcaatag ctacagatac accattggca attcccgcaa caatcccttg
      181 tgcaaatact ttttctgccg cttcttgata aatcacaaca tctccaagtg gtgccaagac
      241 accccaaaca agggcatttg caagtagttg aatgaggtta aaaataagaa tatctttcca
      301 gtcaaaaaca ccattgatca ctcgaacgta ctttctaaaa agtcccacaa ctaaaccaaa
      361 gagtccgcta gcgataatcc aagtccacca tagaccataa ccagcaagag agtccttgat
      421 tgcatgacca atcaacccga caagcaaacc gataatcggt ccaaaaataa tagaaagtag
      481 cgcttgtacc gcatactgaa gctggatgct tgtatttgga acaggggttg gaatgttgat
      541 catcccgatg acgacaaaga gggcagcgcc aattccgaca gcaacaactt gtttaattgt
      601 aaatttgatt tccatactat tctcctattt tatccttcta ttttctttat ttcaatggtc
      661 caagatgaac cgacacctac attataggcc ttggcaaagg aaccttggtt gatagccaaa
      721 cctaaacgat agagagagtt gatgtaaagg atgggttgcc caattctcac atctgcaaat
      781 gatttgccat agacaacctg attttgatag accagcatat cagcatgata gatggtcact
      841 tcaaaacgat caccaaattc tggttccagc ttgtaaaatt cttcccgtgt gatagaggtc
      901 caaagcgaac cgaaacgcac atccagaata tcaatggctc ccttcaccag atgatcttct
      961 atgatggtcg ctacgactgg aagctctaca atctggtcca cactgagctc tggccctact
     1021 tcctcaaaag taatgtgacc actggccagt ttagcaccag tataggcata gacatcacga
     1081 ccgtggaagg tataagaatg ctctgtgttt tgacgcctat tggccacctc agaaatctca
     1141 cgaatggcta caatgccaac gtgtttcttg ataaaggaaa gcgtcccatt atctggcgtg
     1201 acaatgtatt gattttttgc agtcttggca actacactct tacgtttcga accgacacct
     1261 ggatcgacaa ccgatacaaa cgtcgttccc tcaggccagt aatccaccgt ctgaaagaga
     1321 cgatagctcc cctcaaaaat attataaggc gtgatatcgt gcgtcaagtg atggattttt
     1381 aaggttggag actcttctaa agccactcca atcatagccg ataccgcacc atcaaccaga
     1441 ccaaagtctg attgtaatac cagtaaatta ttattcattt tatctccttg tatatccttt
     1501 atcataccat atttcagaga aagtcgctaa tagctatttc aattggttag ggtatagttt
     1561 taccttatag cgaattttca ctaaaagctc ttgttattag ctagtaggtg cattttttct
     1621 tgaaaaaggg tatgatagtt acatcatgaa aaagtaggtt ttattatgaa aattatcctt
     1681 gtcggagggg gaaaagttgg ttttgccctc tgtcgctcct tggttgcaga aaagcatgat
     1741 gttttgctga ttgagcaaga cgaagctgtt ctcaatcata ttgtcagtcg ctttgatatc
     1801 attggtatcc ttggtaacgg ggccgatttt gccattcttg agcaagccag cgtccaagat
     1861 tgtgatatct ttatcgccct gactgagcac gatgaagtca acatgattgc agcagttcta
     1921 gccaagaaaa tgggagctaa agaaactatc gttcgggtga ggaaccctga atattctaac
     1981 tcttatttca aggaaaagaa tattctcggt ttttctctta tcgttaatcc tgagctcttg
     2041 gctgcccgcg ctatcgcgaa tatcattgac ttccccaacg ccctgtctgt cgaacgcttt
     2101 gctggtggac gcgttagcct catggaattt gtcgtcaagt ccaccagcgg tctttgccaa
     2161 atgcccattt ctgattttcg taaaaaattt ggtaatgtca ttgtctgtgc gatagagagg
     2221 gatcatcaaa ttatcattcc aagcggtgac atgactgtac aggataaaga tagaatcttt
     2281 gtcactggta accgtgtcga tatgatactc ttccataatt attttaaatc acgcgccgtg
     2341 aagagccttc tcatcgttgg agcaggtaga attgcctatt atctacttgg tattctcaaa
     2401 gatagtcgta tcgatacaaa agtcattgaa atcaatcctg aaatcgccag cttctttagc
     2461 gagaaattcc caaatctcta catcgttcaa ggagatggaa ccgcaaaaga tatcctgctg
     2521 gaagaaagtg ctcaacacta tgatgccgtt gcgactctaa caggagtcga tgaggaaaat
     2581 ctgattacat ctatgttcct tgacagggta ggtgtacaga aaaatattac taaggtcaat
     2641 cgtaccagtc tcctcgagat tatcaatgcg cctgattttt caagtatcat cacacctaaa
     2701 agcatcgctg tagatacgat tatgcacttt attcgtggtc gagttaatgc ccagtattca
     2761 gaccttcaag ccatgcacca tctagccaat ggccaaatcg aaaccctgca attccatatc
     2821 aaggaagcca ataaaatgac tgccaaacct ctttctcaac tgaaattgaa aaaaggggtt
     2881 cttattgcag ccattattcg aaagggcaag actattttcc caactgggga ggatatgttg
     2941 gaagttggag acaagctcct agtaacaacc ttgttgccaa acatcaccaa gatttatgac
     3001 ttgattgcga ggtaagaaat gaataaaagt atgattcgtt acctcctttc aaagttactt
     3061 ttgattgaag ctgttctcct cttggttcct gtggctatcg ctgtctatta ccgtgaatcg
     3121 agccaagtct ttacagccct cttttcgacc atagggattc tcgtattgtt aggcggttca
     3181 gggagtttac agaagccaaa aaatcaacgg atttatgcca aggagggagt cttgatcgtt
     3241 gccctctgtt ggatcctttg gtctttcttt ggtggtctcc cctttgtctt ttctgggcaa
     3301 atccctagcc ttattgatgc cttttttgaa attagttctg ggtttacaac tactggagca
     3361 agtattttga acgacatttc ggttctcagc cgttccctcc tcttctggcg aagttttacc
     3421 cacttgattg gagggatggg agtgcttgtt tttgcacttg ctattatgga caatgccaaa
     3481 aatagtcacc tagaagtaat gaaggctgag gttcctggtc ctgtctttgg taaggttgta
     3541 tccaaattaa aaaacactgc ccagatcctc tatctccttt acatagccct cttttccctc
     3601 tttgtcatca tctattatct agccggtatg cctctctacg atagttttgt cattgctatg
     3661 gggacagcgg gaactggagg atttaccgtc tataacgatg gaattgccca ctatggtagc
     3721 tcactgatta cctatctggt tagtatagga gttttggttt ttggggtaaa tttcaatctc
     3781 tactactacc ttatgctccg tcgggttaag gccttctttg gagatgaaga gcttcgggct
     3841 tacttggtca tcgtgctggt ttctacaggc ttgattagcc tcaatactct ctacctctac
     3901 ccagggtttt caaagagctt tgaaatgacc ttcttccagg tttccaacat cattacaaca
     3961 actggttttg gatatggaga tattaccaac tggcccctct tctcccagtt tatcctcctt
     4021 ttcctcatgg caatcggtgg ctctgctgga tcaactgcag gtggactcaa gattattcga
     4081 ggcctcatcc tttcaaaaat tgccaaaaac caaattttgt caatcctatc gccccaccgt
     4141 gttttgaccc tccatgttaa taaaatggtg attgacaaag atacccagca taagattctc
     4201 aagtactttg tcatctatgc tatgattttg ctagcgctta tctttattgt cagcctagat
     4261 agcaatgatt ttctggtcgt gaccagcgct gtctttagct gtttcaataa tatcgggcct
     4321 attctaggaa ccacttctag tttctcaatc tttagtccca tctcaaaaat tctcctctcc
     4381 tttgcaatga ttgcagggcg cttggagatt tacccaatcc tccttctctt tatgaaaaga
     4441 acttggtcta agagataaaa tacaaaatcc ctctttttac aattgtgaaa gagggatttt
     4501 tatattaaaa agggggaacg tttttaaatc caagcctgtc tgtaagcaaa gttcttactc
     4561 aaataaaaga tggaaaaact tactacacag cttggtaatg ctccaataca aattgtaagg
     4621 ctttacttgg attctttgtt aaatgaatat attccattcc tctggtagca actatctgaa
     4681 tacctaatct ttctgcatcc accttcatct ctctataata actccgaact tgtggagcca
     4741 gaataattaa atcataaaca cccataatat cataatgagc tccgtacgct cctgaattcg
     4801 caatcactct aacttctgct aattgagcgc cctcgttaat tgcattggct aattacgcac
     4861 ttgttccaga ccctgcacaa agaaccagta ctttcaactc cttacttttt attacatcta
     4921 tctcaccagg cattatttca cttgtatcct cctctaaaat aatatcattt gagcttgcaa
     4981 tatctataac ctgtagtaga tatctcgtat ttagacaata tgaaaacaag acgacttcca
     5041 tataggaaac cgccttctcg ctatgttgag tgatttatat taaaataact tttcttctag
     5101 ctgcatttta ttattataaa aacattcatc ataaccccca gaacttaaat aacaattttt
     5161 attcaagata catactccta gaataaactt tatatgaaat tctcattttt gtttttacaa
     5221 ttctccttag ttaaatcttg tttaatatat gttttacata tagtatttag cgccacatag
     5281 tactgaactc tctccaaaaa cggttattcc tctttgaata gggcgttatc acaagaaaag
     5341 catctccacg tttcaacttc atatggctca aaaacaatca attgatgcta aaacctgtac
     5401 ctagatgttt cggttcataa aaccatgaaa ctgtaaaagt ggatgaaatt gatagcgata
     5461 gtcaaatcaa gaggcatcat aactctaaaa agtcacaata tataagttca tcctcggaaa
     5521 aatatcattc taattgttga aatgcctaca tgaaaagaaa cgtcaaatgc tcatgaaaca
     5581 acgaatacag gtatcaaaac tatgacaaaa caaatcccta aatttactaa agacactgct
     5641 caactttaca cctgtaaatg gttgttgtat aataaagtta caaagatgta cgaccacact
     5701 gttgtaaatc atagtgttcg cgaatatatt actgatagca tttctacaaa tacaagtaaa
     5761 gagagcggat gagattcaaa cgaaatatgt cagtgctttg gcattcctag ccttcatatc
     5821 atttaaagaa ttctatagac aaaatttttt ccaatacaga cactcgtaac aactgcttca
     5881 tttttctacc aacatattta ggaacaggat aagatacaag agtattaatc catagctcag
     5941 ttctatacca atctaagaca aataagctaa aaaaacgatt gataataagc aaatagattc
     6001 caaattttct ctatctgctc attttaataa acaatactag tgtaactatc cttccagtca
     6061 gaagcttgtc aaatcacacc gaaaattctt ctaaaattta tctcgttagg caatcaagca
     6121 aaaactcgac gatagtacaa acattatcat acaggattga cttcctaaat tatatacttt
     6181 agtaaggttt tcggataaga aaaaaggttc attttacatt tctaaacatt cttttctaag
     6241 atgaaaaaca gaatttttcg attgtgattt aaagcaacaa gaagattttc agtatcatcc
     6301 tatagatacg agctaattaa gaaaaactac atttttgaat ataaactaca ataatataaa
     6361 ctaaatttta taggaggaag acaatggatt ggtacgatta tatgatacag gcatccaaac
     6421 aatcacaatt caacgcaagc cattggtttc gctatttgcg aaaagttatt tttgaagact
     6481 attcttattt aacaaaccaa gatgtagaaa agttgctaga ctccaaagaa ctaacccgtt
     6541 ttcaaaaaat tagcttgaag tatgcctttc aagagcatac tccaactcat aaatatgtga
     6601 tttcattaaa taaacctgct aagttaacca atgttcaaaa attgatggag aaatacaaac
     6661 atggataaaa tgaaaccggt cttccaagcc ctaaataagg aattaattca ggaaaatctg
     6721 actttaacaa ttatctgtgt cggtggttat gtcttagaat atcatggttt acgtgccaca
     6781 caagatgttg atgcttttta tgaccaaaat cagaaaatca atgaaattat tgctcgtgta
     6841 ggaaaacagt ttaatcttaa catccacgaa gagttatggc tcaacaatca tgttgcaaag
     6901 caaatatgaa caaacaacct cccttaagtt tatgcgaatc cttgtactca tttgagaatc
     6961 tgaccgtttt agtagtccct attgagtatg tgttaggaat gaagatgatg agtatcagag
     7021 agcaggattt gcaagatatt ggtgcaatta ttaaatacaa aaactttcat tcaccattcg
     7081 atacctttaa atatttaaaa gacatgggat ttgatactat tgacctctct gttctatcta
     7141 gaaggtttta gttatgctta tggtatggat tggttagaaa aattttttaa agaaaatcaa
     7201 gataaacttc gcgaatttta ttaacagtat caaacaagat gattgtcaat tagccagtcg
     7261 tcttgttttt tatgatgaaa tgaaataaaa tctgaacaaa tcgcttagag aattccagtc
     7321 aatttctagc gctgtttgag acgtttcagt ggactatagt aaaatgaaat aagaatagga
     7381 caaatcgatc aggacagtca aatcgatttc taagaatgtt ttagaaataa aggtgtacta
     7441 ttctagtttc aatctattat atttcagatt cggtccacta ttccttccca aaaacattgc
     7501 atattgcgtc aaaggaattg ctcacactat cccaagcaca aaaccctcag tcgattgacc
     7561 gagggttcct ttttattatt caagaacttg attagctcaa tgcatccaag gcgtcatcca
     7621 ttgaaagaac ttcgtggaag acacgttgtg tcaattcagt tttttgttct ggagtgaggt
     7681 atttagtgtt tacacagtat ccagagatac gtacgataac gtcttcgcct gacatgatct
     7741 tttcgtaaac atcgttcaag tccataacgt tcaagttaac gtgttgtcca ccgttttcga
     7801 agtaaccatc aaggattgtt accaagttat caacttgttc atcacgagtc ttaccaagag
     7861 cgcgaggtga tacttgtgta gtcaatgaga taccgtcagc tgcataacta aagtcaaggc
     7921 tagaaagtga gttcaagttt tgcaaccaac cacctttagc tttgttagat gggttagcac
     7981 ctggtgagaa gaattcaagt ttagacaagt tcacagaacc atcttcgttg aggtatacac
     8041 ctttgtgaac tggtgagtta ccagtttgtt tagagtaagc aacgttagat gtgattgtca
     8101 aaagtgatac tgtagcttct gcgtctttgt atagtttgtg gctacgtaga cgagttgtgt
     8161 aagcttcgat caaccattct gccaattcgt ttgaacgtgg gtcatcttca ccccagcgtg
     8221 ggtagtcacc gattgtttcg taatcgtaga tgtagccatc ttcgtcacgg attggtttaa
     8281 ctgtagcgta tttgatagct gacaatgtat caacagtgtt agcaaatcca cagataccga
     8341 atcccatgtt ggcacgttgt ttagttggca agaaggccat ttgaacagct tcgtagttgt
     8401 acctatcagt catgtagtgg atgatgttca aggcatctac gtaagtgtca gtcaaccagt
     8461 caagagattt ttcaaagttc gctttaactg attcgaattc aagaacttcg tcacggattg
     8521 gttcgatatc aaatactttg tagtctttgt gaacatcgtc gtaaccacca ttcaaaccag
     8581 taagaagggc tttaagaacg tttacacgag caccgaagta ctggatgttg tggcgttgtt
     8641 cttcattttc tggatcaagt ggagacacac agcatgagat acagctcatt tcaccatatc
     8701 cgtctttagc cattgttgtt acaccttcgt attggataga agagtgtttg tggctcatgt
     8761 gcatacagta gcgacggaag ttgtatggca atttgtcagt ccaaagaact gtcaagtttg
     8821 gttctggtga gttaccgatg ttgtcaagag tgttcaagaa acggtagtcc atcttagtaa
     8881 cacggtgacg accgtcgtta cccataccag ccatagaagt tgtgataaag gttgggtcac
     8941 ctgagtacaa ttggtcataa gcttttgtac gagcaaattt aactgtacga agtttcataa
     9001 cgaaatcatc aacgaattct tggatttctg attcagtaaa tgtaccacga gcaaggtcac
     9061 gttctgcaaa gatgtccaat acgattggta cacgacctag agatgtagca gcaccgttaa
     9121 tcacacggca gacagccatg aaagcaatgt taacccattg gattgcttct ttcacgttca
     9181 tcgctggttt gcgaacatca accccgtaaa ggtcacccag gcgaacaact tgttgcaatg
     9241 cttggtattg aaggtttact tcttcacgaa gacggattgt ttcttcatcg atttctttga
     9301 ttgcattcca gtcgtttact ttttcttgca tcaagtagtc tgcaccgtaa agagcaagac
     9361 gtgcgtaaac accgatgata cgtccgcgtg agtatgcatc tggaagacca gttacagtgt
     9421 gtgcatgacg agcgcgacga atatttgaag tgtaggcacg gaaaataccg tcgttaactg
     9481 ttgttacata tttagtgaag atttcgtgaa cagctgggtc tggttcgtat ccattttctt
     9541 ttaaagtagt ttcagccata cggataccac cttttggcat gaagttcaat ttgaagagtt
     9601 catcattttg gataccaaag ataacttcat tttctttgtc gataaatcca gcagggatat
     9661 cagcgataga tgttggacga gtgtccattg ggaaacgagt ttcttcgtag tgtgctttag
     9721 tttcttctac aattttcttg atgtgaagtg aacgctctgt tggtcctgca aggaagcttt
     9781 cgtctccatc ataaggtgtg tagttagctt gtacaaagcg tgatacactt gctttttctt
     9841 tccaatctac gcctttgaag ccttcccaag ctttgtcaaa aatatcttgt gcttcaacaa
     9901 ctgtcttaac aaccatatta atatcctctt ttttctagta acagtcatct gttacattca
     9961 taagacaagt ataccataaa gtaaccgatt tcaacaagtg caaaatccct atttttacac
    10021 tttcttttct aaaacagtct atattttatt tcaaactgta ttatattttt gaaaaaaata
    10081 aagtcctttt ttcttttttt cagaaaaaag ggtataataa aagaaaataa gcagtaacac
    10141 tcaatggaaa tcgaaaagca aactaggaag ctagccgcag attgctcaaa acactgtttt
    10201 gaggttgcag atagagctga cgtggtttga agagattttt gaaaagtata aaaaggtgct
    10261 aggcatgttg atttttcctt tgttaaatga tttgtcaaga aaaatcatcc atattgacat
    10321 ggatgccttt tttgctgcag tggaaatcag ggataatcct aaactcagag gaaaacctgt
    10381 cattattgga agcaaccctc ggcaaacagg tggacgggga gtcgtttcta cctgtagtta
    10441 tgaggcaaga gcttttggtg tccattctgc catgagttcc aaggaagctt atgaacgttg
    10501 tccccaggct gtctttatct cagggaatta tgagaaatac aagtctgtgg gactccagat
    10561 tcgagctatt tttaagcgct atacagattt gattgaaccc atgagtattg acgaagccta
    10621 tttggatgtg acagaaaata aactcggtat caagtcagcg gtcaaaattg ctcgcctcat
    10681 tcaaaaagat atctggcaag aactccatct aactgcttct gccggtattt cctataacaa
    10741 gttcttagct aaaatggcga gtgattatca aaaacctcat ggtttgacag tgattctacc
    10801 tgaacaggct gaggattttc tcaaacaaat ggatatttcc aaatttcatg gagtaggaaa
    10861 aaagacagta gaacgtcttc atcaaatggg cgtttttact ggtgctgatt tacttgaagt
    10921 tcctgaggtg accctaatag accgttttgg tagactaggc tatgatctgt atcgaaaggc
    10981 tcgtggcatt cacaactctc cagtcaaatc caatcgcatc cgtaaatcaa tcggcaagga
    11041 gaaaacctac gggaagattc tccgtgctga ggaagatatc aaaaaagagc tgactcttct
    11101 atcagaaaaa gtcgctctca atctacatca acaagaaaaa gctggaaaaa ttgtcatttt
    11161 gaaaatccgc tacgaggact tttcaactct taccaaacga aaaagtcttg ctcaaaaaac
    11221 acaagatgct agtcagataa gccaaatagc cctgcaactc tatgaagaat taagtgagaa
    11281 agaaagaggt gtccgcctat tggggattac catgactgga ttttaaagct caatgaaaat
    11341 caaagagcaa actaggaggc tagccgcagg ctgctcaaaa cactgttttg aggttgcaga
    11401 taaagctgac gcggtttgaa gagattttct aagagtataa aaccttgaag agttgcccct
    11461 tcaaggtttt tcttatacaa ataaacggac aaaactgtaa agtagcaaaa cactaccaag
    11521 cacgatacgg tatttaccaa aaagggtgaa gtcgtgtttt ttcacatagc tggtcaagaa
    11581 gcgaatagcc accatgctga ccgcaaaagc tactcccatc gcgaccaaga gcaaaaacaa
    11641 ttgcccaaag ctcaagagtt ctccggcttt cacaaatttg aaaatcttta aggcactagc
    11701 tccaaacata acaggaatcc caagatagaa ggtaaattct gtcacaactg aacgactggt
    11761 tccatttaac aaaccaccga caatcgttgc acctgaacgg ctagtccctg gtaaaagagc
    11821 aagaacttgg aagagtccga tatagaaagc ggtcgtataa ggaagcttgt ccaactctgt
    11881 tacacttggc tcgatagcac gcgctttatt gcgcttttcc aaatagatga aggcaatccc
    11941 gtagataatc aacatgagag caactgaaac catgttatgg aagtgggtat caaaccaatc
    12001 atcaaattta aagacaccaa gtaaaggtaa agtagcaatc aagaccttca accatagtct
    12061 ccaagtctta cgaacttcct gtttgtcctt agtcggttta aaaggattga gcttgttaaa
    12121 ataaatcacc ataactgcta aaatagcacc aagctgaatc acgacattaa acatggacat
    12181 aaaggcttca ttttgatttt ggtattggat aaactcctct gctaaaatca agtgacctgt
    12241 actggaaatc ggcaaccatt ccgtaattcc ttcaacaatc ccgaagaaga tagattttaa
    12301 aatttcaata agatacatat atttctcctt atattatatt taacgcagtt agctactgcc
    12361 aaagcccaag tggtatactt ggaataagcc actgtggatt agttcatttc ctccaatcgc
    12421 ttgacgattt ccgaaagggt ctaaccacag ctttttgttt caattggtaa tgagtttgat
    12481 aacgcataga cgttttatct cgtctaaggt aacaaggcaa aaagttcgtg gataaccaag
    12541 tagacttgaa atactatatc tggaggtact cccatgcttt atgtgggcat tgatgtcgct
    12601 aaaaataaac acgatgttac agccttgaat gttcgaggaa aactgttctt aaaccactca
    12661 ctttttcaaa taataaagct ggttttgaac tcttagatct gtcttttcga cagctcaacc
    12721 aagactgtc
//
LOCUS       DBEJHE010000047        12406 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC4 isolate 671759
            SAMN38261586-rid24793303.denovo.47, whole genome shotgun sequence.
ACCESSION   DBEJHE010000047 DBEJHE010000000
VERSION     DBEJHE010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261586
            Sequence Read Archive: SRR26833752
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 12406)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12406)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576136.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576136.1
            Genome Coverage       :: 109x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 19:48:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,067
            CDSs (total)                      :: 2,029
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 131
            CDSs (without protein)            :: 131
            Pseudo Genes (ambiguous residues) :: 0 of 131
            Pseudo Genes (frameshifted)       :: 64 of 131
            Pseudo Genes (incomplete)         :: 59 of 131
            Pseudo Genes (internal stop)      :: 46 of 131
            Pseudo Genes (multiple problems)  :: 32 of 131
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12406
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261586-rid24793303.denovo.47"
                     /strain="GPSC4"
                     /isolate="671759"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            1..606
                     /locus_tag="ACL3EZ_001875"
                     /pseudo
     CDS             1..606
                     /locus_tag="ACL3EZ_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            797..3088
                     /gene="pcrA"
                     /locus_tag="ACL3EZ_001876"
     CDS             797..3088
                     /gene="pcrA"
                     /locus_tag="ACL3EZ_001876"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000992850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_process: GO:0006268 - DNA unwinding involved in DNA
                     replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HGR0393397.1"
                     /translation="MNALLNGMNDRQAEAVQTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     IDEKLVNPWNILAITFTNKAAREMKERAYSLNPATQDCLIATFHSMCVRILRRDADHI
                     GYNRNFTIVDPGEQRTLMKRILKQLNLDPKKWNERTILGTISNAKNNLIDDVAYAAQA
                     GDMYTQIVAQCYTAYQKELRQSESVDFDDLIMLTLRLFDQNPDVLTYYQQKFQYIHVD
                     EYQDTNHAQYQLVKLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPKAKVVL
                     LEENYRSTKTILQAANEVIKNNKNRRPKNLWTQNADGEQIVYYRADDELDEAVFVART
                     IDELSRSQNFLHKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDIIA
                     YLNLIANLSDNISFERIINEPKRGIGLGTVEKIRDFANLQNMSMLDASANIMLSGIKG
                     KAAQSIWDFANMMLDLREQLDHLSITELVESVLEKTGYVDILNAQATLESKARVENIE
                     EFLSVTKNFDDTTDVTEEETGLDKLSRFLNDLALIADTDSGSQETSEVTLMTLHAAKG
                     LEFPVVFLIGMEENVFPLSRATEDPDELEEERRLAYVGITRAEKILYLTNANSRLLFG
                     RTNYNRPTRFINEISSDLLEYQGLARPANTSFKASYSSGSISFGQGMSLAQALQDRKR
                     GAAPKSIQSSGLPFGQFTAGAKPASSEANWSIGDIALHKKWGEGTVLEVSGSGARQEL
                     KINFPEVGLKKLLASVAPIEKKI"
     gene            3131..3811
                     /gene="radC"
                     /locus_tag="ACL3EZ_001877"
     CDS             3131..3811
                     /gene="radC"
                     /locus_tag="ACL3EZ_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000286923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HGR0393398.1"
                     /translation="MYSISFQEDSLLPRERLAKEGVEALSNQELLAILLRTGTRQVSV
                     FEIAQKVLNNLSSLTDLKKMTLQELQSLSGIGRVKAIELQAMIELGHRIHKHETLEME
                     SILSSQKLAKKMQQELGDKKQEHLVALYLNTQNQIIHQQTIFIGSVTRSIAEPREILH
                     YAIKHMATSLILVHNHPSGAVAPSQNDDHVTKLVKEACELMGIVLLDHLIVSHSNYFS
                     YREKTDLI"
     gene            complement(3808..4497)
                     /locus_tag="ACL3EZ_001878"
     CDS             complement(3808..4497)
                     /locus_tag="ACL3EZ_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HGR0393399.1"
                     /translation="MKKPVIGITGNEKAHPDDDIMMSYAAKGFVEGVKDAGGIPIILP
                     IGDQEMACHYISLIDKLILTGGQNVDPKFYGEPKTIDSDDYHLQRDIFELTLIKEAIK
                     QKKPIFSVCRGTQLFNVAMGGTLYQDIEDHWQDSSVEYTTQRLVTEPDTVLQEIYGEI
                     SHINSFHHQSIKDLAPNLKVVAHDPKDGIIEAVMSTDDVAFLGVQWHPELLFENRPKD
                     KKLFDYVVNEL"
     gene            complement(4515..5156)
                     /locus_tag="ACL3EZ_001879"
     CDS             complement(4515..5156)
                     /locus_tag="ACL3EZ_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HGR0393400.1"
                     /translation="MKDKQFAIPKATAKRLSLYYRIFKRFHAEKIERANSKQIAEAIG
                     IDSATVRRDFSYFGELGRRGFGYDVKKLMTFFADLLNDNSITNVMLVGIGNMGHALLH
                     YRFHERNKMKIIMAFDLDDHPEVGTQTPDGIPIYGISQIKDKIKDADVKTAILTVPSV
                     KSQEVANLLVDAGVKGILSFSPVHLHLPKDVVVQYVDLTSELQTLLYFMRKED"
     gene            complement(5239..5454)
                     /locus_tag="ACL3EZ_001880"
     CDS             complement(5239..5454)
                     /locus_tag="ACL3EZ_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HGR0393401.1"
                     /translation="MFELTYKDCYHVERTLKYEDHEALMLTLSGCVTLPDTLYVTSLT
                     FRGKKVYQGLVGDLYRFLSHADFLHQN"
     gene            complement(5462..5809)
                     /locus_tag="ACL3EZ_001881"
     CDS             complement(5462..5809)
                     /locus_tag="ACL3EZ_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HGR0393402.1"
                     /translation="MAFEKIIQLKNCRYDYTLSPSVKKFTLKDNTFFETKVGNYELTR
                     LLEKVPNSGEGFQLKIIINKELTGAKINITDKFGLRLVDIFKSEDHHIHQEKFYFLMD
                     SLVERGVFTKSER"
     gene            complement(5814..6929)
                     /locus_tag="ACL3EZ_001882"
     CDS             complement(5814..6929)
                     /locus_tag="ACL3EZ_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase family protein"
                     /protein_id="HGR0393403.1"
                     /translation="MIYLDNAATTPMSAVAISAMTKVMQETHGNPSSIHGHGRQAGKL
                     LREARQELAQLLRTKPQHIFFTSGGTEGNNTTIIGYCLRHQEQGKHIITTAIEHHAVL
                     ETIDYLVQHFGFEATIIQPENQEITAQQIQKALRDDTILVSTMFANNETGNLLPIAEI
                     GQILKQHPAAYHVDAVQAIGKIPIHSEELGIDFLTASAHKFHGPKGIGFLYASSMDFD
                     SYLHGGDQEQKKRAGTENLPAIVGMVAALKEDLEKQEEHFQHVQNLETAFLAELEGIQ
                     YYLNRGKHHLPYVLNIGFPGQKNDLLLLRLDLAGISISTGSACTAGVVQSSHVLKAMY
                     GANSERLKESLRISLSPQNTVEDLQTLAKTLKEIIGG"
     gene            complement(6939..7898)
                     /locus_tag="ACL3EZ_001883"
     CDS             complement(6939..7898)
                     /locus_tag="ACL3EZ_001883"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HGR0393404.1"
                     /translation="MSDRKNMKLFALNSNQEIAQKIAQAVGVPLGKLSSRQFSDGEIQ
                     VNIEESVRGYDVYIIQSTSFPVNNHLMELLIMVDACVRASAHSINVVLPYFGYARQDR
                     IACPREPLTAKLVANMLVKAGVDRILTLDLHAVQVQGFFDIPVDNLFTVPLFAKHYCD
                     KGLLGSDVVVVSPKNSGVKRARSLAEYLDAPIAIIDYPQDDATRNEGYIIGDVEGKKA
                     ILIDDILNTGRTFSEASKIVEREGATEIYAVSSHGLFVEGAAELLDNTNIKEILVTDS
                     VATKEKTPKNVCYITASELIGDAIVRIHERKPVSPLFAYNKKK"
     gene            complement(8011..8580)
                     /locus_tag="ACL3EZ_001884"
     CDS             complement(8011..8580)
                     /locus_tag="ACL3EZ_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HGR0393405.1"
                     /translation="MKHLEIELKTLLKKDEYNRLKDQFTGVTPVLQTNYYIDTPDFEL
                     REKKVAMRIRTFEDWAELTLKVPQSVGNMEYNQKLQLKDAEDYLSKEELPQGLVLDEL
                     AKHGIQSKNWQVLGCLTTLRYEMKTAIGLMALDQSRYFDMTDYELELEVENHEQGKQD
                     FRQFLEKNQISYQKAPSKLVRFVKSMKNS"
     gene            8708..9379
                     /locus_tag="ACL3EZ_001885"
     CDS             8708..9379
                     /locus_tag="ACL3EZ_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015969 - guanosine tetraphosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HGR0393406.1"
                     /translation="MTLEWEEFLDPYIQAVGELKIKLRGIRKQYRKQNKHSPIEFVTG
                     RVKPIESIKEKMARRGITYATLEHDLQDIAGLRVMVQFVDDVKEVVDILHKRQDMRII
                     QERDYITHRKASGYRSYHVVVEYTVDTINGVKTILAEIQIRTLAMNFWATIEHSLNYK
                     YQGDFPDEIKKRLEITARIAHQLDEEMGEIRDDIQEAQALFDPLSRKLNDGVGNSDDT
                     DEEYR"
     gene            9363..10181
                     /locus_tag="ACL3EZ_001886"
     CDS             9363..10181
                     /locus_tag="ACL3EZ_001886"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003951 - NAD+ kinase activity [Evidence
                     IEA];
                     GO_process: GO:0006741 - NADP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HGR0393407.1"
                     /translation="MKNTGKRIDLIANRKPQSQRVLYELRDRLKRNQFILNDTNPDIV
                     ISIGGDGMLLSAFHKYENQLDKVRFIGLHTGHLGFYTDYRDFELDKLVTNLQLDTGAR
                     VSYPVLNVKVFLENGEVKIFRALNEASIRRSDRTMVADIVINGVPFERFRGDGLTVST
                     PTGSTAYNKSLGGAVLHPTIEALQLTEIASLNNRVYRTLGSSIIVPKKDKIELIPTRN
                     DYHTISVDNSVYSFRNIERIEYQIAHHKIHFVATPSHTSFWNRVKDAFIGEVDE"
     gene            10178..11074
                     /locus_tag="ACL3EZ_001887"
     CDS             10178..11074
                     /locus_tag="ACL3EZ_001887"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HGR0393408.1"
                     /translation="MRFEFIADEHVKVKTFLKKHEVSKGLLAKIKFRGGAILVNNQPQ
                     NATYLLDVGDYVTIDIPAEKGFETLEAIELPLDILYEDDHFLVLNKPYGVASIPSVNH
                     SNTIANFIKGYYVKQNYENQQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQKKSIE
                     KRYFALVKGDGHLEPEGEIIAPIARDEDSIITRRVAKGGKYAHTSYKIVASYGNIHLV
                     YIHLHTGRTHQIRVHFSHIGFPLLGDDLYGGSLEDGIQRQALHCHYLSFYHPFLEQDL
                     QLESPLPDDFSNLITQLSTNTL"
     gene            11118..12092
                     /gene="pta"
                     /locus_tag="ACL3EZ_001888"
     CDS             11118..12092
                     /gene="pta"
                     /locus_tag="ACL3EZ_001888"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008959 - phosphate acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006086 - acetyl-CoA biosynthetic process
                     from pyruvate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HGR0393409.1"
                     /translation="MEVFESLKANLVGKNARIVLPEGEEPRILQATKRLVKETEVIPV
                     LLGNPEKIKIYLEIEGIMDGYEVIDPQHYPQFEEMVSALVERRKGKMTEEDVRKVLVE
                     DVNYFGVMLVYLGLVDGMVSGAIHSTASTVRPALQIIKTRPNVTRTSGAFLMVRGTER
                     YLFGDCAININPDAEALAEIAINSAITAKMFGIEPKIAMLSYSTKGSGFGESVDKVVE
                     ATKIAHDLRPDLEIDGELQFDAAFVPETAALKAPGSTVAGQANVFIFPGIEAGNIGYK
                     MAERLGGFAAVGPVLQGLNKPVNDLSRGCNADDVYKLTLITAAQAVHQ"
BASE COUNT         3636 a         2372 c         2675 g         3723 t
ORIGIN      
        1 tatgtgcgag aatatcgaac ttatgaagaa attgcggctg attttggtat ccacgaaagc
       61 aacttactcc gtcggagcca atgggttgaa gtaactcttg ttcaaaggtg gtgttacgat
      121 ttcaagaact cctctcagct ctgaggacac ggtaatgatt gatgcgacgg aagtaaaaat
      181 caatcgccct aaaaaagaat tagcgaatca ttctggtaaa aagaaatttc acgctatgaa
      241 ggctcaagcg attgtcacaa gtcaagggag aattgtttct attgtcatga tatgaagttg
      301 ttcaaaatga gtcgcagaaa tattggacaa gctggtaaaa tcttggctga cagtggttat
      361 caagggctca tgaagatata tcctcaagca caaactccac gtaaatccag caaactcaag
      421 ccactaatag ctgaagataa agcttataac catgcgctat ctaaggagag aagcaaggtt
      481 gagaacatct ttgccaaagt aaaaacgttt aaaatgtttt caacaaccta tcgaagtcat
      541 cgtaaacgct tcggattacg aatgaatttg agtgctggta ttatcaatca tgaactagga
      601 ttctagtttt gcaggaagtc tattgaggta ttgagctagt ttatgaaaaa attgggtgaa
      661 aagtcgagtg ttttagaaac ccacagtgta gtattctagt ttcaatccac tatattttgc
      721 tactccccgt aaagtttcta ttttccctga tttctgatat aatagaaata ttgacttcaa
      781 gagtaaggaa gagaagatga acgcattatt aaatggaatg aatgaccgtc aggctgaggc
      841 ggtgcaaacg acagaaggtc ccttgctaat catggcaggg gctggttctg gaaagactcg
      901 tgttttaacc caccgtatcg cttatttgat tgatgaaaag ctggtcaatc cttggaatat
      961 cttggccatt acctttacca acaaggctgc gcgtgagatg aaagagcgtg cttatagcct
     1021 caatccagct actcaggact gtctgattgc gaccttccac tccatgtgtg tgcgtatttt
     1081 gcgtcgcgat gcggaccata ttggctacaa tcgtaatttt acaattgtgg atcctggtga
     1141 acagcgaacg ctcatgaaac gtattctcaa acagttgaac ttggatccta aaaaatggaa
     1201 tgaacgaact attttgggga ccatttccaa tgctaagaat aatttgattg atgatgttgc
     1261 ttatgctgcc caagctggcg atatgtatac gcaaattgtg gcccagtgtt atacagccta
     1321 tcaaaaagaa cttcgtcagt ctgaatccgt tgactttgat gatttgatta tgctgacctt
     1381 gcgtctcttt gatcaaaatc ctgatgtttt gacctactac cagcaaaaat tccaatacat
     1441 ccacgttgat gagtaccaag ataccaacca cgctcagtac caattggtca aactcttggc
     1501 ttcccgtttt aaaaatatct gtgtggttgg ggatgcggac cagtctatct acggttggcg
     1561 tggtgctgat atgcagaata tcttggactt tgaaaaggat taccccaaag ccaaggttgt
     1621 cttgctggag gaaaattacc gctcaaccaa aaccattctc caagcggcca acgaggttat
     1681 taaaaataat aaaaatcgcc gtcctaaaaa tctctggact caaaacgctg atggggagca
     1741 aatcgtttac tatcgtgccg atgatgagct ggatgaggct gtatttgtag ccagaaccat
     1801 cgatgaactt agtcgcagtc aaaacttcct tcataaggat tttgcagttc tctatcggac
     1861 taatgcccag tcccgtacaa ttgaggaagc cctgctcaag tctaacattc cttataccat
     1921 ggttggcgga accaaattct acagccgtaa ggaaattcgc gatattattg cttatctcaa
     1981 ccttattgct aatttgagtg acaatattag ttttgagcgt attatcaacg agcctaaacg
     2041 tggaattggt ctaggtacag ttgagaaaat ccgtgatttt gcaaatttgc aaaatatgtc
     2101 tatgctggat gcttctgcta atattatgtt gtctggtatc aagggtaagg cagcccaatc
     2161 tatctgggat tttgccaata tgatgcttga tttgcgggag cagctagacc acttaagcat
     2221 tacagagttg gttgagtccg tcctagaaaa aacaggttat gtcgatattc ttaacgccca
     2281 agcgactcta gaaagcaagg cacgggttga aaatatcgaa gagtttcttt ctgttacgaa
     2341 gaactttgat gacaccacgg atgtgacaga agaggaaact ggtctggaca aactgagtcg
     2401 tttcttaaat gacttggctt tgattgccga cacagattca ggtagtcagg agacatcaga
     2461 agtgaccttg atgaccctgc atgctgccaa aggtctcgaa tttccagttg tctttttgat
     2521 tgggatggaa gaaaatgtct ttccacttag tcgtgcgact gaagatccag atgaattaga
     2581 agaagagcgc cgtctagcct atgtaggtat cacgcgtgca gagaaaattc tctatctgac
     2641 caatgccaac tcacgcttgc tttttggtcg taccaattat aaccgtccga ctcgttttat
     2701 taacgaaatc agttcagact tgcttgagta tcaaggtctg gctcgtcctg caaatacaag
     2761 ctttaaggca tcatatagca gtggtagtat ttcctttggt caaggtatga gtttggctca
     2821 ggctcttcaa gaccgtaaac gcggtgctgc cccaaaatca atccagtcaa gcggtcttcc
     2881 atttggtcaa tttacagctg gcgcaaaacc agcatctagc gaggcaaatt ggtccattgg
     2941 tgatattgct ctccacaaga aatggggaga gggaaccgtt ctggaagttt caggtagcgg
     3001 tgctaggcag gaattgaaaa tcaatttccc agaagtaggt ttgaaaaaac ttttagccag
     3061 tgtggctcca attgagaaaa aaatctaatt ttccatcctt ctcacgaata ataaagtgag
     3121 gaggattttt atgtacagta tttcattcca agaagattca ctattaccaa gagaaaggct
     3181 ggccaaggaa ggagttgaag cgcttagtaa ccaagagttg ctagctattt tactcaggac
     3241 aggaacacgt caagttagcg tttttgaaat tgcccaaaaa gtcttgaaca atctttcaag
     3301 cctaacggat ttgaaaaaaa tgaccctgca ggaattgcag agtttgtctg gtattgggcg
     3361 tgttaaggcc atagaattac aagctatgat tgaactgggg catcgtattc acaaacacga
     3421 gactcttgaa atggaaagta ttctcagcag tcaaaagttg gccaagaaga tgcagcagga
     3481 attaggggat aaaaaacaag agcacctggt ggcactctat ctcaatactc aaaatcaaat
     3541 catccatcag cagaccattt ttatcgggtc tgtaactcgt agtatcgctg aaccgcgaga
     3601 gattcttcac tatgcaatca agcatatggc gacttctctt atcttggtcc acaatcatcc
     3661 ttcaggagcg gtagcgccta gccaaaatga tgatcatgtc actaaacttg ttaaagaagc
     3721 ctgcgaattg atggggattg ttctcttgga ccatttgatt gtctctcatt ctaattactt
     3781 tagttatcgt gaaaagacag atttaatcta aagttcatta acgacatagt caaagagttt
     3841 tttatctttg ggacgatttt caaaaagaag ttctggatgc cattggacac cgagaaaggc
     3901 gacatcatcc gtactcatga cagcctcaat gataccatct ttaggatcat gagccacaac
     3961 ttttaaattt ggtgctaagt ccttgatgct ctggtggtgg aaggagttga tatgagagat
     4021 ttctccatag atttcttgga gaacggtatc tggttctgtt accaagcgtt gagttgtgta
     4081 ctcaacagaa gaatcctgcc aatggtcttc gatatcttgg tacaaagttc cacccatggc
     4141 aacgttaaag agttgggtac cacggcagac agagaaaatg ggctttttct gtttaatagc
     4201 ttccttgatg agggtcagtt cgaagatatc tctttgaagg tgatagtcat cgctatcaat
     4261 ggttttgggt tcgccataaa attttggatc gacattttgc ccacctgtca agatgagctt
     4321 gtcaatcaaa ctgatatagt ggcaggccat ttcttgatca ccaatcggta ggatgatggg
     4381 aatccctcca gcatctttaa cgccttcaac aaagcctttt gctgcgtagc tcatcatgat
     4441 gtcatcatct ggatgagctt tttcgtttcc tgtaatccca ataactggtt ttttcataaa
     4501 atgattttcg ctttctaatc ctcttttcgc atgaagtaga ggagggtttg gagttcactt
     4561 gtcaaatcga catactgaac gaccacgtct tttggtaaat gcagatggac tggtgaaaaa
     4621 ctgagaattc ctttcacacc agcatcaacc aagagattag caacctcttg tgacttgacg
     4681 ctgggaacag ttaggatagc agtcttcaca tcagcatcct tgattttatc cttgatctga
     4741 gaaatcccgt aaatgggaat cccgtcagga gtttgggtac cgacttcagg atggtcgtct
     4801 aggtcaaagg ccatgataat cttcatcttg ttacgttcgt ggaagcggta gtggagaagg
     4861 gcatggccca tatttccaat accaaccagc atgacattgg taatagagtt gtcattgagc
     4921 aaatcggcaa aaaatgtcat tagttttttg acatcatagc caaaaccacg acgaccaagt
     4981 tcaccaaaat aggaaaaatc acgacgtacg gtcgctgaat caataccgat agcctctgca
     5041 atttgcttag agttggcacg ttcaatcttt tctgcatgaa atctcttaaa aattcgatag
     5101 tagagagaga gtctttttgc tgtagctttt ggaatagcaa actgtttatc tttcacaaaa
     5161 tcacaacctt tctattcttc tattttatag aaacattgtg aaaaaatcaa caaaaataag
     5221 aaaaaactaa gaaaaatctt agttttgatg taaaaaatct gcatgagata gaaaacggta
     5281 gaggtctccg accagcccct gataaacttt tttgccccta aaagtcagag aagtcacata
     5341 aagtgtatct ggtaaggtta cacatcctga caaagtcaac atgagagcct catgatcctc
     5401 atacttgaga gtacgctcta catgatagca gtccttatag gtcagttcaa acattttggc
     5461 tctatctttc cgattttgta aagacaccac gttctaccaa gctatccatg aggaagtaga
     5521 atttttcctg atgaatatgg tggtcttctg atttgaaaat atcaactaga cgaaggccaa
     5581 acttgtcagt gatattgatt ttagcccctg taagttcctt gttaatgatg attttgagtt
     5641 ggaagccttc accgctgttt ggcacttttt ccaaaaggcg agtcagttca tagttaccaa
     5701 ccttagtttc aaaaaaggtg ttatctttga gggtgaattt tttaacagaa gggctaagag
     5761 tgtaatcgta acgacaattt tttaactgaa tgattttttc aaatgccata tggctaacct
     5821 ccgataattt cttttaaggt ttttgcgagg gtttgtaggt cttcaacggt attttgtggc
     5881 gacaaactga tgcgaaggga ttccttcaag cgttctgaat ttgcgccata catggcttta
     5941 agaacatggc tggattggac aacgcctgca gtacaggctg agccagtaga gattgaaatt
     6001 ccagctaaat ctagccgaag gagtaagagg tcatttttct gaccaggaaa tccaatattg
     6061 agaacataag ggagatgatg ttttcctcta ttcaagtaat actgaatgcc ctccagctct
     6121 gccagaaagg cagtttctag attttgtaca tgttgaaaat gttcttcttg tttttctagg
     6181 tcttctttta gggctgcaac catgcctacg atggcaggca gattttcagt tcctgcacgt
     6241 tttttctgtt cctgatctcc gccatgtaga taggaatcaa agtccatgct agatgcgtag
     6301 agaaaaccga ttcccttagg accatggaat ttgtgggcag aagcagtgag aaaatcaatg
     6361 cccaattctt ctgaatgaat tgggatttta ccaatagcct gaactgcatc aacatgatag
     6421 gcagcagggt gttgcttgag tatttggcca atttcagcga tgggaagtag gtttcctgtc
     6481 tcattattgg caaacatagt agaaaccaaa atcgtatcgt cacgtaaagc cttttgaatt
     6541 tgctgggctg tgatttcttg attttctggc tggataatgg ttgcttcaaa cccaaagtgt
     6601 tgaaccaagt aatcaattgt ttcaaggaca gcatggtgct cgatggcagt tgtgatgata
     6661 tgttttcctt gttcttggtg acgaagacag tagccaatga tggtagtatt attgccttca
     6721 gtcccaccag aagtgaaaaa gatatgttga ggttttgtcc ttagtaactg ggctagttcc
     6781 tgacgggctt ctcgcaagag tttgccagct tgacgaccat gaccatgaat actagaagga
     6841 tttccgtggg tttcttgcat aaccttggtc atagctgaaa tagcaactgc tgacatagga
     6901 gtcgttgcag cattgtccaa ataaatcaaa gaatcacctt atttcttttt attgtaggca
     6961 aagagtgggc tgactggttt tctttcgtga atacggacga tagcatcacc aattaactca
     7021 ctagcagtga tgtagcatac atttttagga gttttttctt ttgttgctac tgaatcagtc
     7081 acaagaattt ctttaatatt agtattgtca agaagctcag cagctccctc gacgaagaga
     7141 ccgtggctag aaacagcata aatttctgta gctccttcac gttcaacgat tttagaagct
     7201 tcagagaagg tacgtcctgt atttaaaata tcatcaatca agatagcttt cttaccttca
     7261 acatcaccaa taatataacc ttcgttacga gttgcatcgt cttgagggta gtcgataatg
     7321 gcgataggag catcaagata ttcagccagg ctacgcgcac gtttgacacc tgaattttta
     7381 gggctaacga caacaacatc tgaaccaagc aatcctttat cgcagtaatg ttttgcgaat
     7441 aggggaacag tgaaaagatt atccactgga atatcaaaga aaccttgaac ctgaacggca
     7501 tgcaaatcaa gagtcaggat acgatcaact ccagccttaa ccagcatatt ggcaactagt
     7561 tttgctgtaa gtggctcacg aggacaagca atgcggtctt gacgtgcata gccaaaatat
     7621 ggaaggacaa cgttgatact gtgggcactt gcacgcacac aagcatcgac catgattaac
     7681 aattccatta ggtggttgtt gacagggaaa cttgttgatt ggatgatgta aacatcataa
     7741 ccacggacac tttcttcgat atttacttgg atttctccgt ctgaaaattg acgtgatgat
     7801 agttttccaa gtgggacacc aacagcttgg gcaatttttt gtgcaatctc ttggttagag
     7861 ttgagtgcga aaagtttcat gttttttcta tctgacatta tagaccgtcc tctgtaaact
     7921 ttataaatcc tagttatatt taccttacat atatgaactg ggatttgtgt atttttatct
     7981 tttctatttt accaaaaaat ggagattatt tcagctattt ttcatacttt tgacaaatcg
     8041 aaccaatttt gaaggagctt tttggtagga aatctgattt ttctctaaaa attgtcggaa
     8101 atcctgtttg ccttgctcat gattttccac ttcaagctcc aattcgtaat ctgtcatatc
     8161 aaagtatcgg ctctgatcca gtgccatgag accaatagct gttttcattt catagcgaag
     8221 cgttgttaga caaccaagaa cctgccagtt cttactttgg ataccatgtt tcgccaattc
     8281 atccagtact agtccttgag gaagttcttc cttgctcaga taatcttcag catcttttag
     8341 ttgcaatttt tggttgtatt ccatgtttcc aacactctgc gggactttga gtgtcaactc
     8401 agcccagtct tcaaaggttc gaatgcgcat agcgactttc ttttctcgca gttcaaaatc
     8461 aggcgtgtcg atgtagtaat ttgtttgaag aacaggagtg acacctgtga actggtcttt
     8521 tagacgattg tattcatctt ttttcaatag tgttttcaat tcaatttcta aatgtttcat
     8581 ttttcttacc tttttttatc gttgaaagcg gatttatggt ataataagca ttgtatttat
     8641 tgtatatgaa tctggagaaa aaatcaaaga tatttttgac ggataatatg agaacaaggg
     8701 agaatatatg accttagaat gggaagaatt tctagatcct tacattcaag ctgttggtga
     8761 gttaaagatt aaacttcgtg gtattcgtaa gcaatatcgt aagcaaaata agcattctcc
     8821 aattgagttt gtgaccggtc gagttaagcc aattgagagc atcaaagaaa aaatggctcg
     8881 tcgtggcatt acttatgcga ccttggaaca cgatttgcag gatattgctg gcttacgtgt
     8941 gatggttcag tttgtagatg acgtcaagga agtagtggat attttgcaca agcgtcagga
     9001 tatgcgaatc atacaggagc gagattacat tactcataga aaagcatcag gctatcgttc
     9061 ctatcatgtg gtagtagaat atacggttga taccatcaat ggagttaaga ctattttggc
     9121 agaaattcaa attcgtactt tggccatgaa tttctgggca acgatagaac attctctcaa
     9181 ctacaagtac caaggggatt tcccagatga gattaagaag cgactggaaa ttacagctag
     9241 aatcgcccat cagttggatg aagaaatggg tgaaattcgt gatgatatcc aagaagctca
     9301 ggcacttttt gatcctttga gtagaaaatt aaatgacggt gtaggaaaca gtgacgatac
     9361 agatgaagaa tacaggtaaa cgaattgatc tgatagccaa tagaaaaccg cagagtcaaa
     9421 gggttttgta tgaattgcga gatcgtttga agagaaatca gtttatactc aatgatacca
     9481 atccggatat tgtcatttcc attggcgggg atggtatgct cttgtcggcc tttcataagt
     9541 acgaaaatca gcttgacaag gtccgcttta tcggtcttca cactggacat ttgggcttct
     9601 atacagatta tcgtgatttt gagttggaca agctagtgac taatttgcag ctagatactg
     9661 gggcaagggt ttcttaccct gttctgaatg tgaaggtctt tcttgaaaat ggtgaagtta
     9721 agattttcag agcactcaac gaagccagca tccgcaggtc tgatcgaacc atggtggcag
     9781 atattgtaat aaatggtgtt ccctttgaac gttttcgtgg agacgggcta acagtttcga
     9841 caccgactgg tagtactgcc tataacaagt ctcttggcgg tgctgtttta caccctacca
     9901 ttgaagcttt gcaattaacg gaaattgcca gccttaataa tcgtgtctat cgaacactgg
     9961 gctcttccat tattgtgcct aagaaggata agattgaact tattccaaca agaaacgatt
    10021 atcatactat ttcggttgac aatagcgttt attctttccg taatattgag cgtattgagt
    10081 atcaaatcgc ccatcataag attcactttg tcgcgactcc tagccatacc agtttctgga
    10141 accgtgttaa ggatgccttt atcggtgagg tggatgaatg aggtttgaat ttatcgcaga
    10201 tgaacatgtc aaggttaaga ccttcttaaa aaagcacgag gtttctaagg gattgctggc
    10261 caagattaag tttcgaggtg gagctattct ggtcaataat caaccgcaaa atgcaacgta
    10321 tctattggac gttggagact acgttaccat tgacattccc gctgagaaag gctttgaaac
    10381 cttggaggct attgagcttc cattagatat tctctatgag gatgaccact ttctagtctt
    10441 gaataaaccc tatggagtgg cttctattcc tagtgttaat cactctaata ccattgccaa
    10501 ttttatcaag ggttactatg tcaagcaaaa ttatgaaaat cagcaggttc acattgttac
    10561 cagactagat agggacactt ctggcttgat gctctttgcc aagcacggtt atgcccatgc
    10621 acgattagac aagcagttgc agaagaaatc tatcgagaaa cgctactttg ctttggttaa
    10681 gggagatgga catttggaac cagaagggga aattattgct ccgattgcgc gtgatgaaga
    10741 ttccattatt accagacgag tggctaaagg cggaaagtat gcccatactt catacaagat
    10801 tgtagcttct tatggaaata ttcacttggt ctatattcac ctgcacactg gtcgaaccca
    10861 tcaaatccga gtccattttt ctcatatcgg ttttcctttg ctgggagatg atttgtatgg
    10921 tggtagtctg gaagatggta ttcaacgtca ggctctgcat tgccattacc tatcctttta
    10981 tcatccattt ttagagcaag acttgcagtt agaaagtccc ttgccggatg atttcagtaa
    11041 ccttattacc cagttatcaa ctaatactct ataaaaactg tctcagagta taattattat
    11101 cttaaaggag aaaactcatg gaagtttttg aaagtctcaa agccaacctt gttggtaaaa
    11161 atgctcgtat cgttctccct gaaggggaag agcctcgtat tcttcaagca acaaaacgct
    11221 tagtaaaaga aacagaagtg attcctgttt tgcttggaaa tcctgaaaaa attaaaattt
    11281 atcttgaaat tgaaggaatc atggatggtt atgaggtcat cgaccctcaa cattatcctc
    11341 aatttgaaga aatggtttct gccttggtgg agcgtcgcaa gggcaaaatg actgaagaag
    11401 atgtacgcaa ggttttggtt gaagatgtca actactttgg tgtgatgttg gtttacttgg
    11461 gcttggttga tggaatggtg tcaggagcga ttcactcaac agcttcaaca gttcgcccag
    11521 ctctacaaat catcaaaact cgtccaaatg taactcgtac ttcaggagcc ttcctcatgg
    11581 ttcgtggtac ggaacgttac ctatttggag actgtgccat taatatcaat ccagatgcag
    11641 aagccttggc tgaaattgcc atcaactcag caatcacagc taagatgttt ggcatcgaac
    11701 ctaaaattgc catgttgagc tattctacta aaggttcagg gtttggtgaa agcgttgata
    11761 aggtcgttga agcaactaaa attgctcacg acttgcgtcc tgaccttgaa atcgatggtg
    11821 agttgcaatt tgatgcggcc tttgttcccg aaactgcagc tctgaaagct ccgggaagta
    11881 cagtagctgg tcaagcaaat gtcttcatct tcccaggtat cgaggcagga aatatcggtt
    11941 acaagatggc tgaacgcctg ggtggctttg cggctgtagg acctgttttg caaggtttaa
    12001 acaagccagt taatgatctt tctcgtggat gtaatgcaga tgatgtttac aagttgaccc
    12061 tcatcacagc agctcaagca gttcatcaat agtgaaaact ataaagtgat atactatgct
    12121 atactgtagt tatgaaacta tgtacgaaaa gcactgccat taattcctga gaactaaatt
    12181 actgattggt gtcaaaaagg aaaacttcca agcgatgata tcctgtctat acacgaccta
    12241 tagaaatctg taatatacat atccgtaaaa cgataaattc cctttttgat tttaaatgag
    12301 tatgaaaaga gaattttttg gctctttgtc aactgtagtg ggttgaagtc agctaagctc
    12361 gagaaaggac aaattttgtc ctttcttttt tgatgttcag ggcgat
//
LOCUS       DBEJHE010000048        10664 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC4 isolate 671759
            SAMN38261586-rid24793303.denovo.48, whole genome shotgun sequence.
ACCESSION   DBEJHE010000048 DBEJHE010000000
VERSION     DBEJHE010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261586
            Sequence Read Archive: SRR26833752
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 10664)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10664)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576136.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576136.1
            Genome Coverage       :: 109x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 19:48:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,067
            CDSs (total)                      :: 2,029
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 131
            CDSs (without protein)            :: 131
            Pseudo Genes (ambiguous residues) :: 0 of 131
            Pseudo Genes (frameshifted)       :: 64 of 131
            Pseudo Genes (incomplete)         :: 59 of 131
            Pseudo Genes (internal stop)      :: 46 of 131
            Pseudo Genes (multiple problems)  :: 32 of 131
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10664
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261586-rid24793303.denovo.48"
                     /strain="GPSC4"
                     /isolate="671759"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(8..1222)
                     /locus_tag="ACL3EZ_001889"
     CDS             complement(8..1222)
                     /locus_tag="ACL3EZ_001889"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HGR0393410.1"
                     /translation="MKEYNKSSKLEHVAYDIRGPVLEEAMRMRANGEKILRLNTGNPA
                     EFGFIAPDEVIHDLIMNARDSEGYSDSKGIFSARKAIMQYCQLKKFPNVDIDDIYLGN
                     GVSELIVMSMQGLLDNGDEVLVPMPDYPLWTAAVSLAGGNAVHYICDEAVEWYPDIDD
                     IKSKITSNTKAIVLINPNNPTGALYPKELLLEIIEIARQNDLIIFADEIYDRMVMDGH
                     VHTPVASLAPDVFCVSMNGLSKSHRIAGFRVGWMVLSGPKTHVKGYIEGLNMLSNMRL
                     CSNVLAQQVVQTSLGGHQSVDELLLPGGRIYEQRNFIYNAIQDIPGLSAVKPKAGLYI
                     FPKIDRNMYRIDDDEQFVLDFLKQEKVLLVHGRGFNWQEPDHFRIVYLPRVDELAQIQ
                     EKMTRFLKQYRR"
     gene            complement(1378..1672)
                     /locus_tag="ACL3EZ_001890"
                     /pseudo
     CDS             complement(1378..1672)
                     /locus_tag="ACL3EZ_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009014348.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1834..2286
                     /locus_tag="ACL3EZ_001891"
     CDS             1834..2286
                     /locus_tag="ACL3EZ_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HGR0393411.1"
                     /translation="MAQRYQNIMVAIDGSKEADLAFVKGVHSALRNDAKLTIAHVIDT
                     RALQSVSTFDAEVYEELQVDAESLMKEYEKRAKDAGVADVHIVIEMGNPKTLLARTIP
                     DAEEVDLILVGATGLNAFERLLVGSSSEYILRHAKVDLLVVREQEKTL"
     gene            complement(2321..3709)
                     /locus_tag="ACL3EZ_001892"
     CDS             complement(2321..3709)
                     /locus_tag="ACL3EZ_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HGR0393412.1"
                     /translation="MEVKAVFFDIDGTLVNNRKSVLKSTKDAIKIVKEQGVLVGVATG
                     RGPFFVKELMDDLDLDFAVTYNGQYIFSKDRVLFTSPISKLHLRHLISYAKKEGTEIA
                     LGTKDAMLGSKIMSFGLGSFSQRISRFVPSVLTRTVSQSFNRMVSKVVPQKEEDLLHL
                     MNQPIYQVLMLMTPEESEKAAADFEDLKLTRSNPFASDVINQGNSKLEGIRRVGKEYG
                     FDLNQVMAFGDSDNDLEMLAGVGMSVAMGNGSSSVKEAAKHITTSNQQDGIHKALEHF
                     GVLSSEKVFVSRDYHFNKVKTFHHMMDERTQEEPRAWDLEGATHRAGFKIEELVEFVR
                     SASPSEEDFGQAVSQLHQALDKAAGKVAKKTPAQQDLIGQVDALIDTLYFTYGSFVLM
                     GVDPERIFDIVHQANMGKIFPDGKAHFDPVTHKILKPDNWEEKYAPEPAIKKELQRQL
                     KAYERHKERNKS"
     gene            3775..4737
                     /locus_tag="ACL3EZ_001893"
     CDS             3775..4737
                     /locus_tag="ACL3EZ_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HGR0393413.1"
                     /translation="MPKKILVLHTGGTISMQADASGAVVTSSDNPMNHVSNPLEGIQV
                     HALDFFNLPSPHIKPKHMLVLYQKIKEEADNYDGVVITHGTDTLEETAYFLDTMEVPH
                     MPIVLTGAMRSSNELGSDGVYNYLSALRVASDDRAADKGVLVVMNDEIHAAKYVTKTH
                     TTNVSTFQTPTHGPLGLIMKQEILYFKTAEPRVRFDLDHIQGLVPIISAYAGMTDELI
                     DMLDLEHLDGLIIQAFGAGNIPKETAQKLESLLQKGIPVALVSRCFNGIAEPVYAYQG
                     GGVQLQKAGVFFVKELNAQKARLKLLIALNAGLTGQALKDYMEG"
     gene            complement(4943..5953)
                     /gene="ccpA"
                     /locus_tag="ACL3EZ_001894"
     CDS             complement(4943..5953)
                     /gene="ccpA"
                     /locus_tag="ACL3EZ_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000990602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0001228 - DNA-binding transcription
                     activator activity, RNA polymerase II-specific [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HGR0393414.1"
                     /translation="MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEV
                     IDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFSSLAKGIDDIAEMYKYNIVLANS
                     DEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
                     VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGL
                     VFESKYSYDDGYALAERLISSNATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSD
                     DSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREVLLPHGLTERSSTRK
                     RK"
     gene            complement(6378..6977)
                     /locus_tag="ACL3EZ_001895"
     CDS             complement(6378..6977)
                     /locus_tag="ACL3EZ_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGR0393415.1"
                     /translation="MKVLVAEDQSMLRDAMCQLLTLQPDVESVLQAKNGQEAIQLLEK
                     ESVDIAILDVEMPVKTGLEVLEWIRSEKLETKVVVVTTFKRAGYFERAVKAGVDAYVL
                     KERSIADLMQTLHTVLEGRKEYSPELMEMVMTRPNPLTEQEIAVLKGIARGLSNQEIA
                     DQLYLSNGTIRNYVTNILSKLDAGNRTEAANIAKESGWL"
     gene            complement(6979..8076)
                     /locus_tag="ACL3EZ_001896"
     CDS             complement(6979..8076)
                     /locus_tag="ACL3EZ_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HGR0393416.1"
                     /translation="MLERLKSIHYMFWISLIFMVFPILTVVTGWLSAWHLLIDILFVV
                     AYLGVLTTKSQRLSWLYWGILLTYVVGNTAFVAVNYIWFFFFLSNLLSYHFSVGGLKS
                     LHVWTFLLAQVLVVGQLLIFQRIEVEFLFYLLVILAFVDLMTFGLVRIRIVEDLKEAQ
                     AKQNAQINLLLAENERNRIGQDLHDSLGHTFAMLSVKTDLALQLFQMEAYPQVEKELK
                     EIHQISKDSMNEVRTIVENLKSRTLTSELETVKKMLEIAGIEVETDNQLDTASLTQEL
                     ESMASMILLELVTNIIKHAKASKAYLKLERTEKELILTVSDDGCGFAFLKGDELHTVR
                     DRVFPFSGEVSVISQKHPTEVQVRLPYKERN"
     gene            complement(8076..8813)
                     /locus_tag="ACL3EZ_001897"
     CDS             complement(8076..8813)
                     /locus_tag="ACL3EZ_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0393417.1"
                     /translation="MKRWIALSKIEFLLTKRQLIYYLLSVGMPTAFYLFFSGIYQDTP
                     GELANFMRDYLISMTAFSMMSTAIFSFPVVLHTDKINNWQKTLRHSPVNMVEYYLSKI
                     TSMLVDYLVSILVVFSVGHFVRGVDMSLGNWIGAALLLIVGSIAFVALGLTLTLLPTS
                     QLMSVVGNLLYLGLAVLGGLWMPISLFPDWMQVVGKCLPTYQLMELLKTFLNEGGINL
                     SATVYLLVFSVVLFGLTIYLQGHKENA"
     gene            complement(8815..9699)
                     /locus_tag="ACL3EZ_001898"
     CDS             complement(8815..9699)
                     /locus_tag="ACL3EZ_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0393418.1"
                     /translation="MTVVKVEKLSKKIKDKEILRNISFEINDGECVALIGPNGAGKTT
                     LLDCLLGDKLVTSGQVSIQGLPVTSSKLDYTRAYLPQENIIVQKLKVKELIAFFQRIY
                     PNPLSNQEIDQLLQFVKQQKEQLAEKLSGGQKRLFSFILTLIGRPKIVFLDEPTASMD
                     TSTRQRFWEIVQELKAQGVTILYSSHYIEEVEHTADRILLLNKGELIRDTTPLAMRSE
                     EIEKHFILPIAYKEVVEQSNLVENWTLKQDSLQVVTREADAFWELLAQAGCRMQEIEV
                     NNRSLLNTIFEETQKGDN"
     gene            complement(9686..9880)
                     /locus_tag="ACL3EZ_001899"
     CDS             complement(9686..9880)
                     /locus_tag="ACL3EZ_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0393419.1"
                     /translation="MKRGIIYFFIGLSLLVWLVEMFTDWFDQALLRQFICGALGFGFM
                     IFVVFPMGMEWLKGESHDCG"
     gene            complement(9877..10083)
                     /locus_tag="ACL3EZ_001900"
     CDS             complement(9877..10083)
                     /locus_tag="ACL3EZ_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000503440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0393420.1"
                     /translation="MGEEEMRNKMIIAMSLVVAGVMTYLMFSGLDEDFYHFPWKVFAG
                     FGIMSWLVREGLKLVRDVKKEFEE"
BASE COUNT         3287 a         2416 c         1898 g         3063 t
ORIGIN      
        1 gcaagcccta tctacgatac tgtttcaaga aacgagtcat cttttcttgg atttgggcta
       61 actcatcaac acgaggaagg taaacgatac ggaagtggtc tggttcctgc cagttaaagc
      121 ctcgaccatg aaccaagaga accttttcct gcttcaagaa atcaaggaca aactgctcat
      181 catcatcgat acggtacata ttgcggtcga tttttgggaa gatatagagc cccgccttgg
      241 gtttaacggc agacaaacct ggaatatctt gaatggcatt atagatgaaa tttctttgct
      301 cgtagattcg tccaccagga agaagcaatt catcgactga ttggtgaccc cccaaggaag
      361 tttgtacgac ttgttgggcc aaaacgttag agcaaaggcg catattggac agcatattga
      421 gcccttcgat atagccctta acatgagtct tagggccaga caagaccatc caacccacac
      481 ggaaacctgc tatgcggtgg gattttgaca gaccattcat gctgacacag aagacatctg
      541 gtgccaagct cgccacaggc gtatgcacat gtccgtccat taccatgcgg tcatagattt
      601 catccgcaaa gataatcaaa tcgttttgac gggcaatctc aataatctcc agcaagagtt
      661 ccttaggata aagggctcca gttgggttat ttggattgat aaggacaatt gccttggtat
      721 tggaagtgat ttttgacttg atatcgtcaa tatctgggta ccattccaca gcttcatcac
      781 agatatagtg aacggcattt cctccagcta ggctgacagc cgccgtccat agaggatagt
      841 ctggcattgg cactaagacc tcatccccat tgtccaaaag cccctgcatg gacatgacaa
      901 tcaactcact gacaccattt ccaaggtaaa tatcatcaat atctacgttt gggaatttct
      961 tcagctggca atactgcatg atggccttac gggctgagaa aatccctttg gagtcagaat
     1021 agccttcact atcacgcgca ttcataatca agtcatgaat gacctcgtct ggcgctataa
     1081 agccaaattc tgctggattt cctgtattca gacgtaaaat cttttctcca ttcgctcgca
     1141 tccgcatggc ttcttccaat acaggaccac ggatatcata agcaacatgc tctaacttac
     1201 tagacttgtt atattctttc atcttgtttc ctcaattcat caggatagta acattatacc
     1261 actagaaaga gaatgcgaca agtttactga aatgtgttac tagtttcgta tagaagaaaa
     1321 accttgctaa aggcgaggtt aagaacgtag agatagcagg tattttgcaa agacacatca
     1381 cataccaaaa gataaaccta gaaaaaagca agcctagaaa ggagtcataa agaagattaa
     1441 acatgaggaa aagcccccat atcatcaagt aatcccaacg cccacttcgt tttgcaacta
     1501 gaaataagat tagatggtag agtacatgaa aaactaaaaa tccaataaaa cttggataaa
     1561 gaagcggtac cagactctct aattgacaga tcatgatcac ttctaccaag actgaaacta
     1621 ggataattcc ataataaagg aaatttgatt tttgaaaaga gtttttcatc attctccctt
     1681 ccttcacttc tttcctgcta tcctttcttt tattttatca tatatttata tagagtttaa
     1741 gccctaatat tcttttgaaa aatacttttt ttgctttact tctatagtga aaaggtttac
     1801 aattatagta agaaaatttc aggaggtttc attatggcac aacgttacca aaatatcatg
     1861 gtcgcaatcg atggttctaa ggaagcggac ttggcttttg tcaagggagt tcattctgct
     1921 ctacgaaacg acgctaaact caccatcgca catgtcattg acacacgcgc tctccaaagc
     1981 gtatccacct ttgatgctga agtttacgaa gaactccaag tcgacgctga aagtctgatg
     2041 aaagagtacg aaaaacgtgc taaagatgct ggggtagcag atgttcatat cgtcattgaa
     2101 atgggaaatc caaagaccct gctagcacgt actattccag atgccgagga agtggacctc
     2161 atcctcgttg gcgcaactgg tctcaacgcc tttgaacgcc tcttggtcgg ctcttcatct
     2221 gaatacatac tccgccatgc taaggtcgat ttgctggttg tgagagaaca agaaaaaacc
     2281 ttataatcac aaagaaaagg agcccctagc tcctttttgt ttacgattta tttctctctt
     2341 tatggcgttc gtaagccttg agctggcgct gcagttcctt tttaatagca ggttctggag
     2401 catatttttc ttcccaatta tctggtttta agattttatg ggtcactgga tcaaaatgag
     2461 ccttgccatc tggaaaaatt ttccccatat tggcctgatg gacaatatca aaaatacgtt
     2521 ctgggtccac ccccatcaag acaaaactgc cgtaggtgaa gtaaagcgtg tcaatcaagg
     2581 catccacttg ccctatcaaa tcttgctgag caggtgtctt cttggctact ttacctgctg
     2641 ccttatcaag ggcctgatga agttgcgata cagcttgacc aaaatcttct tcagaaggac
     2701 tggctgatcg aacaaactcc accaattctt ctattttaaa accagcccta tgggttgcac
     2761 cctctaaatc ccaagctcga ggttcttctt gggttcgttc atccatcatg tggtggaagg
     2821 tcttgacctt attgaaatga tagtcacggc tgacaaaaac tttttctgaa gacaaaacac
     2881 caaaatgttc caaggccttg tggatcccat cttgttgatt gctagtggta atgtgcttgg
     2941 cagcttcctt gacactgcta ctaccatttc ccatagcgac cgacataccg acgccagcca
     3001 gcatttcaag gtcattatct gagtcaccaa aagccatgac ttggttgagg tcaaagccat
     3061 attctttccc aactcggcga atgccttcta atttagaatt tccctgattg atgacatccg
     3121 atgcaaaagg attgctacgt gtcaatttca agtcttcaaa atcagctgcc gccttctcag
     3181 attcttctgg tgtcatcagc atcaaaactt ggtaaatagg ttgattcatc aggtgaagca
     3241 ggtcctcttc cttttgggga acaaccttgc tgaccatgcg attaaaagac tgactcaccg
     3301 tccgagttaa aacagaggga acgaagcgac taattcgttg ggaaaaagaa cccagaccaa
     3361 aggacatgat tttagaaccc aacatggcat ccttggtccc taaggcaatc tccgtgccct
     3421 cttttttagc atagctaatt agatggcgca aatgtaactt ggaaataggg ctcgtgaaca
     3481 agactctgtc tttactaaag atatactggc cattataggt taccgcaaaa tccagatcca
     3541 aatcgtccat caattcctta acaaaaaaag gtcctcgccc tgtcgctacg ccaactagta
     3601 ccccttgttc tttgacaatc ttaatcgcat ccttagtgga tttcaaaaca ctcttgcgat
     3661 tgttgaccaa ggttccatcg atatcaaaaa aaacagcttt gacttccatc ctatcccaat
     3721 ctcccctttt gtgatacaat gattatacca catttcagaa agagtgagta aatcatgcct
     3781 aagaaaatcc ttgttttaca tacgggtgga actatttcca tgcaggccga tgcttctggc
     3841 gctgttgtga cgagttcaga taatcccatg aaccatgtgt ccaacccact tgaaggaatc
     3901 caagtccacg ccttggactt ttttaacctt ccaagtcccc atatcaaacc caaacatatg
     3961 ctggtcctct accagaaaat taaagaggaa gcagataact acgatggagt ggtgatcaca
     4021 cacggaaccg atactttaga ggaaacagcc tatttccttg ataccatgga agttccccat
     4081 atgcctatcg ttctaacagg agccatgcgt agctccaatg aactcggtag tgatggtgtt
     4141 tataattacc taagtgcttt acgagtggcc agcgatgaca gggctgctga caaaggagtt
     4201 ttggtcgtta tgaacgatga aatccacgct gccaagtatg tcaccaaaac acatacgact
     4261 aatgtcagca ccttccagac tccaacacat ggcccccttg gtctcatcat gaaacaggaa
     4321 atcctctact tcaaaacagc tgaacctcgt gttcgctttg accttgatca catacaaggt
     4381 ttagtcccta tcatctcggc ttatgctggt atgacagatg agctgattga tatgctggat
     4441 ttagaacact tggacggttt gattatccaa gccttcggag ctggtaatat tcccaaagaa
     4501 acggctcaaa aattagaaag ccttctgcaa aaaggaattc cagtcgctct ggtatcacga
     4561 tgctttaacg gtattgccga gcctgtttat gcctaccagg gtgggggcgt acagttgcaa
     4621 aaagcaggcg ttttctttgt taaagaactc aacgcccaaa aagctcgctt gaaactcctc
     4681 atcgccctca atgccggact aacaggacag gctttgaaag actatatgga aggctaatac
     4741 tcttcgaaaa tctctgcaaa ccacgtcacg tcgccttacc gtatgtatgg ttactgactt
     4801 cgtcagtttc atctacaacc tcaaaacagt gtgttgcgca gcctttaacc agccgcctag
     4861 tccgctctat ggtattcatt aagtcaacat ctcttgttta agagcacaaa atcaggaaat
     4921 cttctcgatt ccctgatttt ttctatttac gttttcgtgt tgagctacgt tctgtcaaac
     4981 catgaggtaa gagaacttca cgttcttcca actcttcctt atgcataatc ttggtcaaca
     5041 tacgcatact aatggcacca aggtcataaa gaggttgggc aatcgttgtc aagtttggac
     5101 gggtaaagcg tgagatttgt gaatcatcac tagtaataat ttcaaaatct tctggcacag
     5161 aaacaccctt atcagccaaa ccgttcaaga ctcctgctgc caactcatca cctgtcacaa
     5221 ctgctgcagt tgcatttgat gaaatcaaac gctctgctaa ggcgtaacca tcatcatagc
     5281 tatatttaga ttcaaatacc aaaccctcac tataagtgat tcctgctttt ttcaaggttt
     5341 ccttgtagcc aactaaacga accttaccat tgatgtcatc cactagcgga ccgctaacga
     5401 aagcaatacg ctcattttct ttagcaaggt aactcactgc atcaattgtt gcttgcttat
     5461 agtcaatatt gacacttggc aactggtgct caacatcgac agttcctgcg agaacaatcg
     5521 gagtacgtga acgcgaaaat tctgagcgaa ttttatctgt caagtgatac cccatataga
     5581 taatgccatc tacctgcttt gaaaagaggg tattgacaac agaaacttct ttctcgttat
     5641 cttcatcgct attagctagg acaatattgt acttgtacat ttctgcaata tcatcaatcc
     5701 ccttagccaa actcgaaaaa taaccattgg taatatttgg aatcacgaca ccgacagtgg
     5761 ttgtcttttt acttgcaaga ccacgcgcaa ctgcatttgg acgataatcc aaacgatcaa
     5821 ttacctctag cactttttta cgggtattct cttttacatt tttattgcca ttgaccacac
     5881 ggctgaccgt cgccatggaa acacctgctt cacgagcgac atcataaatg gttactgtat
     5941 catctgcatt cattcctttt cctgtccttt ctatctcaca cattctttta caagtagagg
     6001 tactgattga agctctatat ctacttacaa aagtgaagat gtgaaaattt cgttttcata
     6061 tttctactta ttccattcta tcactaattg taaacacttt caagtgtttt ttgaagattg
     6121 attgaaaaaa tttcatagaa aacctaggtt tagctccttg ctaccacctt agactaaaca
     6181 aaaaggagga aactaagccc tcctaaagtt atagtaaaat gaaataagaa caggataaat
     6241 cgatcaggac agtcaaatcg atttctaaca atgttttaga agtagaggtg tactattcta
     6301 gtttcaatct actataggta ttgttccatt cactaccgtc aattttagca catagtcttc
     6361 atgaaaatat tatatcatca taaccaacca gattcttttg cgatattagc tgcctctgtt
     6421 cgattaccag catccagttt tgaaagaata ttggtgacat agtttcgaat agttccgttt
     6481 gagaggtaaa gctgatctgc gatttcttgg ttggataagc cccgggcgat tccctttaag
     6541 acagcaatct cttgttctgt caacggattg ggacgggtca tcaccatttc catcaattca
     6601 ggcgaatact ccttgcgtcc ttcgaggacg gtgtgcaagg tttgcatgag gtctgcaatg
     6661 cttcgttcct ttaatacata agcatccact ccagccttga ccgcacgttc aaaataccca
     6721 gcacgcttga aggtcgtcac cacaaccacc tttgtttcaa gcttttctga tcgtatccac
     6781 tccaagactt caagacctgt cttaacaggc atttctacgt caaggatggc gatatctaca
     6841 gactcctttt ctaatagttg gattgcttct tgcccattct tggcttgaag gacagactcc
     6901 acatctggtt gaagcgtgag caattgacac atggcatctc gcaacatact ttgatcttct
     6961 gcgactaata ctttcatctt agtttctctc cttataaggt agtcgaactt gcacttccgt
     7021 tggatgtttc tgactgatta cacttacttc tcctgaaaat ggaaaaacac gatctcggac
     7081 tgtatggagc tcatctcctt ttagaaaagc aaagccgcag ccatcatcac ttactgttaa
     7141 aatgagttcc ttctctgtcc gttctaattt taagtaagct ttagacgctt tggcatgttt
     7201 gatgatattg gtcaccaact caagcaaaat catagaagcc attgactcca attcttgagt
     7261 aaggctagca gtatctagtt ggttatccgt ttccacctca attccagcaa tttctaacat
     7321 ctttttcaca gtctctagtt cggatgtcaa agttctagac ttaagatttt ccacgatagt
     7381 tcgaacttca ttcatggaat ccttgctgat ctggtgaatt tcttttaatt ccttttccac
     7441 ctgtggataa gcctccatct gaaataactg caaggctaga tcagttttaa cactaagcat
     7501 agcaaaggta tgccccagac tatcatgcaa atcttgaccg atacgattgc gttcattttc
     7561 agcaagcaat agatttatct gggcattttg cttagcctgt gcttctttca aatcctccac
     7621 aattcgaatc cgaaccaagc caaaagtcat taaatcgaca aaagcaagaa ttacaagtag
     7681 atagaataga aactcaactt cgattctctg aaaaatcaac agttgaccca caacaaggac
     7741 ttgagcaaga agaaaagtcc agacatgtaa agactttaaa ccacctacgc tgaaatgata
     7801 gcttaagaga ttggatagga aaaagaaaaa ccagatataa ttaacagcca caaaggcagt
     7861 attcccaact acataagtca gcaggatgcc ccaatatagc caagatagac gctggctctt
     7921 agttgttaaa acacccaaat acgccactac aaatagaata tcaatcaata aatgccaggc
     7981 agaaagccac ccagtcacta cagttaggat ggggaaaacc ataaaaatta aactgatcca
     8041 aaacatataa tgtatgcttt tcagtctttc aagcattaag cattctcctt atgaccttga
     8101 aggtaaatgg tcaaaccaaa caaaactact gaaaaaacaa gtaaataaac tgtggctgat
     8161 agattgatgc caccctcatt taagaaggtc ttgagcaact ccatcaactg ataggtcggg
     8221 agacacttac ctactacttg catccagtct ggaaataaag agataggcat ccagagtcca
     8281 cctaaaacag ccaaccctag ataaagaaga ttgcccacga cagacatcaa ctgactagtt
     8341 ggtaagagag tcaaggtcaa accaagcgct acgaaggcaa tacttcctac tatcagcaaa
     8401 agtgcagccc caatccaatt tccaagagac atgtccacac ctcttacaaa atgcccaact
     8461 gagaaaacca ccaagattga aaccaaataa tcaaccagca tacttgttat ctttgataga
     8521 taatattcta ccatatttac agggctatga cgcaatgttt tctgccagtt gttgatcttg
     8581 tcggtatgta aaacaactgg gaatgagaag atagctgttg acatcatgga aaatgcagtc
     8641 atggagataa gataatcacg cataaaattc gcgagttcac ctggtgtgtc ctgatagata
     8701 ccagaaaaaa ataaatagaa agccgtcggc atccctaccg acaatagata atagattaat
     8761 tgtcgtttgg tcaataaaaa ttctatctta ctaagtgcta tccatcgttt catcttagtt
     8821 atctcccttc tgcgtctctt caaagattgt attcaacaaa ctacgattat taacttcgat
     8881 ttcttgcatc ctacatcctg cttgggctaa tagttcccag aaagcatctg cttctcgagt
     8941 gactacttgt aaagaatctt gctttagggt ccagttttca accaaatttg actgctctac
     9001 gacttccttg taagctatag gaaggataaa gtgcttttct atttcctcgc tacgcatagc
     9061 tagaggcgtc gtatctcgaa tcaactctcc cttatttaag agcaaaatgc ggtctgcagt
     9121 gtgttccact tcctcaatat aatgggacga atagagaatg gtgactcctt gcgcttttaa
     9181 ctcctggaca atttcccaaa aacgttgacg agttgaggta tccatggacg cagtaggctc
     9241 atctaaaaaa acaatctttg gtcgcccaat taaggtcaag atgaaagaaa agagacgctt
     9301 ttgaccgcct gataattttt ctgccaactg ttctttttgt tgcttgacaa actgcaatag
     9361 ttgatcaatt tcctgattgc tcaaaggatt tggatagata cgttgaaaga aagcaatcaa
     9421 ctctttaact tttaatttct gaacgattat attttcttga gggaggtaag ccctagtata
     9481 gtctaactta gaactcgtca ctggtaaacc ttgaatagat acttgaccgc ttgtgaccag
     9541 tttatctcca agcaaacaat ctaagagtgt tgtctttccg gcaccatttg gaccaattaa
     9601 ggcaacacat tcaccatcgt tgatttcaaa ggagatgttc cgcaaaattt ccttgtcttt
     9661 tattttctta ctcaattttt caactttaac cacagtcatg agactctcct ttcaaccact
     9721 ccattcccat agggaaaacg acgaaaatca taaatccaaa ccccaaagca ccacaaatga
     9781 attggcgaag caaggcttga tcaaaccaat cagtaaacat ttccactaac cataccaaga
     9841 gtgacaggcc gataaagaaa tagatgatcc ctctcttcat tcctcaaact cctttttcac
     9901 atctctgact aatttcaaac cttctctaac aagccaagac atgattccaa agccagcaaa
     9961 gaccttccaa ggaaaatggt agaaatcctc atccaatccc gaaaacatga gataggtcat
    10021 aactcctgct actactaaac tcattgcaat aatcatttta tttctcatct cttcttcccc
    10081 catttcatac tacaattata gtcttttaaa atcagaggag gcagaagctt ctgtcactag
    10141 aaaatatgac aaatgtcata aaaattctgt tcaaaacaag caagatacac tatacaataa
    10201 aacacaatca gaaaaatcta aggcaacttc ctcaaaagag atatcaaacc caattcacac
    10261 cataatgtaa actaatactt atttaaaatc aaaaagagta gaaattttta tcagacaaac
    10321 acatatatag tgtattgaat ctataacagt aggccttaaa tactaaaata tttctataaa
    10381 ttaatttaac tttcctgata gagctgttca tatcttattt caattctcta tattatacgt
    10441 tgaacaaaac ccttctattg ctttcttaaa aatttataag agttataaaa tctgttaaat
    10501 ttcaatgtgt atacctaaac tacggtattt attgaaaaga ctggagacaa aaagtatacg
    10561 ctgccaaaat gaattactga aaatcaaaaa agagagaacc aaactgattc cctcttaatg
    10621 tatataatat ctagttttaa aaatacacac tcacatatct ctgt
//
LOCUS       DBEJHE010000049         9634 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC4 isolate 671759
            SAMN38261586-rid24793303.denovo.49, whole genome shotgun sequence.
ACCESSION   DBEJHE010000049 DBEJHE010000000
VERSION     DBEJHE010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261586
            Sequence Read Archive: SRR26833752
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 9634)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9634)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576136.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576136.1
            Genome Coverage       :: 109x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 19:48:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,067
            CDSs (total)                      :: 2,029
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 131
            CDSs (without protein)            :: 131
            Pseudo Genes (ambiguous residues) :: 0 of 131
            Pseudo Genes (frameshifted)       :: 64 of 131
            Pseudo Genes (incomplete)         :: 59 of 131
            Pseudo Genes (internal stop)      :: 46 of 131
            Pseudo Genes (multiple problems)  :: 32 of 131
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9634
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261586-rid24793303.denovo.49"
                     /strain="GPSC4"
                     /isolate="671759"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(299..481)
                     /locus_tag="ACL3EZ_001901"
     CDS             complement(299..481)
                     /locus_tag="ACL3EZ_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0393421.1"
                     /translation="MNPIKAFDKIYGNYFLTVQGVKVMKTIKKADHVVVGLGKLFIAD
                     KLMDTARWLIRPEERE"
     gene            complement(483..1262)
                     /locus_tag="ACL3EZ_001902"
     CDS             complement(483..1262)
                     /locus_tag="ACL3EZ_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0393422.1"
                     /translation="MAEQDLAMQVLQQVVKLPVVKVDRSKFLVDKFSKELDPKDIPTL
                     LEQGTTTLLSQEILDRVANACIRDNVLLASGTSVLAGLAGGLAMAITIPADVAQFYAF
                     SLKLAQELGYIYGYEDLWASREELSEDAQNTLLLYLGVMLGVNGTAALLCAGGITIAK
                     QVMKTVPNKALTKTLWYPILKKVLKIFGVNLTKGGLAKGIGKFIPILGGIIAGGLTFA
                     TMKPMGESLQKELSKLVNYSEVQYQEDVETIRKEAEIIKGE"
     gene            complement(1541..1891)
                     /gene="rbfA"
                     /locus_tag="ACL3EZ_001903"
     CDS             complement(1541..1891)
                     /gene="rbfA"
                     /locus_tag="ACL3EZ_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HGR0393423.1"
                     /translation="MANHFRTDRVGMEIKREVNEILQKKVRDPRVQGVTITDVQMLGD
                     LSVAKVYYTILSNLASDNQKAQIGLEKATGTIKRELGRNLKLYKIPDLTFVKDESIEY
                     GNKIDEMLRNLDKN"
     gene            complement(2142..4934)
                     /gene="infB"
                     /locus_tag="ACL3EZ_001904"
     CDS             complement(2142..4934)
                     /gene="infB"
                     /locus_tag="ACL3EZ_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HGR0393424.1"
                     /translation="MSKKRLYEIAKELGKESKEVVARAKELGLDVKSHSSSVEEAVAA
                     KIAASFKPAAAPKVEAKPAAPKVSAEKKAEKSEPAKPAVAKEEAKPAEPVAPKTEKVA
                     VKPQSRNFKAEREARAKEQAERRKQNKGNNRDQQQNGNRQKNDGRNGGKQGQSNRDNR
                     RFNDQAKKQQGQQKRRNERRQQEDKRSNQAAPRIDFKARAAALKAEQNAEYARSSEER
                     FKQYQAAKEALAQANKRKEPEEIFEEAAKLAEQAQQVQAVVEVVPEKKEPAVDTRRKK
                     QARPDKNRDDYDHEEDGPRKQQKNRSSQNQVRNQKNSNWNNNKKNKKGNNKNNRNQTP
                     KPVTERKFHELPTEFEYTDGMTVAEIAKRIKREPAEIVKKLFMMGVMATQNQSLDGET
                     IELLMVDYGIEAKQKVEVDNADIERFFVEDGYLNEDELVERPPVVTIMGHVDHGKTTL
                     LDTLRNSRVATGEAGGITQHIGAYQIVENGKKITFLDTPGHAAFTSMRARGASVTDIT
                     ILVVAADDGVMPQTIEAINHSKAANVPIIVAINKIDKPGANPERVIGELAEHGVMSTA
                     WGGDSEFVEISAKFNQNIEELLETVLLVAEIQELKADPTVRAIGTVIEARLDKGKGAV
                     ATLLVQQGTLNVQDPIVVGNTFGRVRAMTNDLGRRVKVAGPSTPVSITGLNEAPMAGD
                     HFAVYEDEKSARAAGEERAKRALMKQRQATQRVSLENLFDTLKAGELKSVNVIIKADV
                     QGSVEALSASLQKIDVEGVKVTIVHSAVGAINESDVTLAEASNAFIVGFNVRPTPQAR
                     QQAEADDVEIRLHSIIYKVIEEMEEAMKGMLDPEFEEKVIGEAVIRETFKVSKVGTIG
                     GFMVINGKVARDSKVRVIRDGVVIYDGELASLKHYKDDVKEVTNGREGGLMIDGYNDI
                     KMDDVIEAYVMEEIKR"
     gene            complement(4951..5250)
                     /locus_tag="ACL3EZ_001905"
     CDS             complement(4951..5250)
                     /locus_tag="ACL3EZ_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HGR0393425.1"
                     /translation="MNKQKISNLLGLAQRAGRIISGEELVVKAIQDGKAKLVFLAHDA
                     GPNLTKKIQDKSHYYQVEIVTVFSTLELSIAVGKSRKVLAVTDAGFTKKMRSLME"
     gene            complement(5243..5536)
                     /locus_tag="ACL3EZ_001906"
     CDS             complement(5243..5536)
                     /locus_tag="ACL3EZ_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HGR0393426.1"
                     /translation="MKTRKIPLRKSVVSNEVIDKRDLLRIVKNKEGQVFIDPTGKANG
                     RGAYIKLDNAEALEAKKKKVFNRSFSMEVEESFYDELIAYVDHKVKRRELGLE"
     gene            complement(5558..6694)
                     /gene="nusA"
                     /locus_tag="ACL3EZ_001907"
     CDS             complement(5558..6694)
                     /gene="nusA"
                     /locus_tag="ACL3EZ_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor NusA"
                     /protein_id="HGR0393427.1"
                     /translation="MSKEMLEAFRILEEDKGIKKEDIIDAVVESLRSAYRRRYGQSDS
                     VAIDFNEKTGDFTVYTVREVVDEVFDSRLEISLKDALAINSAYELGDKIKFEEAPAEF
                     GRVAAQSAKQTIMEKMRKQTRAITYNTYKEHEQEIMSGTVERFDNRFIYVNLGSIEAQ
                     LSKQDQIPGEVFASHDRIEVYVYKVEDNPRGVNVFVSRSHPEMIKRLMEQEIPEVYDG
                     TVEIMSVAREAGDRTKVAVRSHNPNVDAIGTIVGRGGANIKKITSKFHPARYDAKNDR
                     MVPIEENIDVIEWVADPAEFIYNAIAPAEVDQVIFDENDSKRALVVVPDNKLSLAIGR
                     RGQNVRLAAHLTGYRIDIKSASEFEAMEDAASVELEVENDTVEE"
     gene            complement(6738..7217)
                     /gene="rimP"
                     /locus_tag="ACL3EZ_001908"
     CDS             complement(6738..7217)
                     /gene="rimP"
                     /locus_tag="ACL3EZ_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0042274 - ribosomal small subunit
                     biogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HGR0393428.1"
                     /translation="MDAIATIVELVREVVEPVIEAPFELVDIEYGKIGSDMILSIFVD
                     KPEGITLNDTADLTEIISPVLDTIKPDPFPEQYFLEITSPGLERPLKTKDAVAGAVGK
                     YIHVGLYQAIDKQKVFEGTLLAFEEDGLTMEYMDKTRKKTVQIPYSLVSKARLAVKL"
     gene            complement(7343..7978)
                     /gene="trmB"
                     /locus_tag="ACL3EZ_001909"
     CDS             complement(7343..7978)
                     /gene="trmB"
                     /locus_tag="ACL3EZ_001909"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001266107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008176 - tRNA
                     (guanine(46)-N7)-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HGR0393429.1"
                     /translation="MRVRNRKGATELLEANPQYVVLNPLEAKAKWRDLFGNDNPIHVE
                     VGSGKGAFVSGMAKQNPDINYIGIDIQKSVLSYALDKVLEVGVPNIKLLWVDGSDLTD
                     YFEDGEIDRLYLNFSDPWPKKRHEKRRLTYKTFLDTFKRILPENGEIHFKTDNRGLFE
                     YSLVSFSQYGMKLNGVWLDLHASDFEGNVMTEYEQKFSNKGQVIYRVEAEF"
     gene            complement(7975..8769)
                     /gene="ccrZ"
                     /locus_tag="ACL3EZ_001910"
     CDS             complement(7975..8769)
                     /gene="ccrZ"
                     /locus_tag="ACL3EZ_001910"
                     /EC_number="2.7.1.15"
                     /EC_number="2.7.1.229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000363010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004747 - ribokinase activity [Evidence
                     IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_function: GO:0019200 - carbohydrate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA];
                     GO_process: GO:0051726 - regulation of cell cycle
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell cycle regulator CcrZ"
                     /protein_id="HGR0393430.1"
                     /translation="MDLGDNELTLTPIPGKSGKAYMGSYPDGKRIFVKMNTSPILPGL
                     AREQIAPQLLWSRRLADGRDMCAQEWLTGKILTPYDMNRKQIVNILTRLHRSRPLMTQ
                     LSRLGYAMETPVDLLQSWQETAPDALRKNHFISEVMADLRQTIPGFREDHATIVHGDV
                     RHSNWIETDSGLIYLVDWDSVRLTDRMFDVAHMLCHYISEHQWKEWLTYYGYKYNQTV
                     LSKLYWYGQLSYLSQISKYYMNQDLENVNREIHGLRHFRDKYGKRR"
     gene            complement(8930..9541)
                     /locus_tag="ACL3EZ_001911"
     CDS             complement(8930..9541)
                     /locus_tag="ACL3EZ_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="HGR0393431.1"
                     /translation="MEFFDKFHALCFGFLVLIIVITVPYTINHGGFFQNESALILVSL
                     LVTSLSVAYARKFEMISFGMLSKKQLLLFIAIFLLSVLETLVYIHFFAVSSGSGVQHL
                     AEVSRGISLSLILTTSVFGPIQEELIFRGLLQGAVFDNSWLGLVLTSSLFSFMHGPSN
                     VPSFIFYLLGGLLLGFAYKKSQNLWVSTLVHMFYNSWPLLYYL"
BASE COUNT         2624 a         2245 c         1760 g         3005 t
ORIGIN      
        1 aacatatata ctgcaaggtg aagctgacgt ggtttgaaga gattttcgaa gagtataaaa
       61 tgattttact gcttatatta taccatatgg agagagatta aaaaactagc agtggagttc
      121 ctgctagctc tctgcgactt ggattaccat ctagataagt ttaaagagcc aatccaatat
      181 cttaaataat atcttgtaaa acagcaattg aactgcaaag gaaatgatca tccaaaagaa
      241 tttcacaatc ccaataatcg gtttgataaa aagaatagca agaagaccaa aaaaaatttc
      301 attctctctc ctctggccta atgagccacc gagccgtatc cattagctta tctgcaataa
      361 aaagttttcc cagaccaaca acgacatggt cagctttctt tatcgttttc atcactttta
      421 caccttgcac ggtcaaaaag taattaccat aaattttatc aaaagctttg ataggattca
      481 tattactctc ctttaatgat ttcagcctct tttcggattg tttcaacatc ttcttgatat
      541 tgaacttcac tatagttgac tagcttggat aattctttct gcaagctttc ccccattggt
      601 ttcatagttg caaaggttaa accacctgca atgataccac ccaagatagg aataaatttc
      661 cctattcctt tggccagccc tcccttggta agattcacac caaatatttt taagactttt
      721 ttcaaaatag ggtaccaaag cgtctttgtt aaagctttat taggcactgt tttcattacc
      781 tgtttggcaa ttgttatacc accagcacat agcaaagcag cggttccatt cacccctaac
      841 attacgccta gataaagcaa gagggtattt tgagcatctt cactcaactc ctcgcgtgaa
      901 gcccaaagat cctcataacc ataaatataa cctaattctt gagccaattt cagagagaaa
      961 gcataaaatt gagccacatc agctggaatg gtaattgcca tagcaagccc tccagctaat
     1021 cctgccaaaa cagaagtccc actcgctaat aatacattgt cccgaataca agcattagct
     1081 acacgatcta atatttcttg agatagaaga gtcgttgtac cttgttccaa taaggtagga
     1141 atatcttttg gatccaattc tttggaaaac ttatccacta aaaatttcga acgatcaacc
     1201 ttaacaacag gtagtttcac cacttgttgc aatacttgca tagctaagtc ttgttcagcc
     1261 atatacaaac tccttatttc ttttttacac cttatcatat tatatttcct acaaaaaaag
     1321 cattttctaa ttagataaca ttaaaaaata cagaacccct tttttatagt aaaatgaaac
     1381 aagaacagga caaatcgatc aggacagtca aatcgatttc taacaatgtt ttagaagtag
     1441 aggcgtacta ttctagtttc aatatatttt aaaagaatat ttttccattt caaattcaac
     1501 ctattttcct ccaccaaaaa agaggggcaa cccctcttct ttagttctta tccagattgc
     1561 gtagcatctc gtcaatcttg tttccatact cgatggactc gtctttgacg aaggtcaaat
     1621 ctgggatttt gtacaatttc aaattgcgac caagttcacg tttgatggta ccagttgctt
     1681 tttcaagccc gatttgggct ttttggttat ccgaagcaag gttactcaaa atggtgtaat
     1741 aaaccttggc aacagacaag tcacccagca tctgaacatc tgtgatggtc acaccttgga
     1801 cacgtggatc acggactttc ttttgcaaaa tctcattgac ttcacgcttg atttccatgc
     1861 ccacacgatc tgtacggaaa tgatttgcca tgatattcct ttctctactt tgaaccaaaa
     1921 gctaggccag cagacctagc tattttaaac ttcttgattt tcagtttaaa ttgaaacgaa
     1981 gttcaatttg aagtcatctg cttctttcgc cgtggtgaaa gtgatggaac tgatttatca
     2041 gtcccatcac aggggatttt tgagacccta ggctcaaaaa taagcaatga aaccatcggt
     2101 ttgcttgcgt ccctcaccac ctaagaaagg agcaaaaaat cttatctctt gatttcttcc
     2161 atgacatacg cctcaatcac atcatccatc ttaatatcat tgtagccgtc gatcatcaat
     2221 ccaccttcac gaccgtttgt cacttctttc acgtcgtctt tgtagtgttt caagcttgcg
     2281 agttcgccat catagataac gacaccatca cggataacac ggactttaga gtcacgggca
     2341 accttaccgt tgataaccat aaatccaccg atagttccca ctttagacac cttgaaggtt
     2401 tcacggataa ccgcttcacc aataactttt tcttcaaatt ctggatcaag catccctttc
     2461 atagcttctt ccatctcttc gataaccttg tagataatgc tgtgaagacg gatttccaca
     2521 tcgtcagctt ctgcttgttg acgagcttgt ggtgtagggc gtacgttgaa accaacgata
     2581 aaggcatttg aagcttcggc aagggtcacg tctgattcgt tgatagcacc gaccgctgag
     2641 tggacgatag tcactttgac accttccacg tcaatctttt gaagtgaggc agaaagggct
     2701 tcaacagaac cttgtacatc agccttgatg ataacattaa cagatttgag ttccccagct
     2761 ttaagggtat caaagaggtt ttcaaggcta acacgttggg tagcttgacg ttgtttcatg
     2821 agggcacgtt tggcacgctc ttcacctgct gcacgcgcag atttttcatc ctcgtaaacg
     2881 gcaaagtggt cacccgccat cggtgcttcg ttcaaacctg tgatagagac tggtgttgat
     2941 ggtccagcaa ctttaacacg acgaccaagg tcgttggtca tagcacggac acgaccgaag
     3001 gtatttccga caacgattgg atcttgaaca ttcaaggtac cttgttgtac aagaagggtt
     3061 gcgaccgcac cttttccttt atccaagcgc gcttcgataa ccgtaccgat tgcacgcact
     3121 gttgggtctg ccttgagttc ttggatttca gctacaagaa ggactgtttc caacaattct
     3181 tcgatatttt ggttgaattt agctgagatt tcaacaaatt cagaatctcc accccaagcg
     3241 gttgacatca caccatgctc tgccaattca ccgataacgc gttctgggtt agcacctggt
     3301 ttatcaatct tgttaatggc tacgatgatt ggaacgttag ctgcttttga gtggttgatg
     3361 gcttcaatag tctgaggcat aaccccgtca tctgccgcta cgaccaagat cgtaatatcg
     3421 gtaacagaag caccacgcgc acgcattgat gtaaaggccg cgtgtcctgg tgtatcaagg
     3481 aaggtaatct tcttaccatt ttccacgatt tggtaggcac cgatatgctg agtaatacca
     3541 cctgcttcac ctgtcgcaac acgtgagtta cgaagagtat ccaaaagggt tgttttaccg
     3601 tggtcaacgt gtcccatgat agtaacaact ggtggacgct caaccaattc atcttcattg
     3661 agataaccat cttcgacaaa gaaacgttcg atgtcagcat tatccacttc aaccttttgt
     3721 ttggcttcga taccgtaatc caccatgagg agttcaattg tttccccatc caaggattgg
     3781 ttttgtgtgg ccatgacacc catcatgaaa agtttcttaa caatttcagc tggttcacgt
     3841 ttgatacgtt ttgcgatttc cgcaacggtc ataccatctg tatattcaaa ttctgttggc
     3901 aattcatgga atttacgctc cgtaacaggt tttggagtct gattacggtt gttcttgtta
     3961 ttgccttttt tgttcttttt gttgttattc cagttactat tcttttgatt tctcacttga
     4021 ttttgactac ttcgattctt ttgttgtttt ctaggaccat cttcttcatg atcataatcg
     4081 tcacgatttt tgtctggtcg agcttgtttt ttacgacgtg tatccactgc aggttctttt
     4141 ttctcaggga cgacttcaac cactgcttga acttgctgtg cttgttcagc taacttagcc
     4201 gcttcttcaa agatttcctc tggttccttg cgtttgttag cttgagccaa ggcttcttta
     4261 gcagcctgat actgcttgaa gcgttcctca cttgaacgag cgtactctgc attttgctct
     4321 gcttttaggg ctgctgcacg ggctttaaag tcaatacgtg gagccgcttg atttgaacgt
     4381 ttatcctctt gctgacggcg ctcatttcta cgtttttgct gaccttgctg cttcttagct
     4441 tggtcattaa agcgacgatt gtcgcggttg ctttgacctt gttttccacc attacggccg
     4501 tcgtttttct gacggtttcc gttttgttgt tggtcacggt tattgccctt attttgcttg
     4561 cgtcgttctg cctgctcttt agcacgggct tcacgctcag ccttgaaatt acgactttgc
     4621 ggtttcactg ctactttttc tgttttcgga gcaactggct cagccggttt tgcctcttcc
     4681 ttagctacag ctggtttagc tggctcagat ttttcggctt tcttttctgc acttactttt
     4741 ggtgctgcag gttttgcttc tactttcgga gcagctgcag gcttaaagct ggcagcaatt
     4801 tttgcagcga cagcttcttc cacacttgat gagtggcttt tcacatccaa gcccaactct
     4861 tttgcacgcg ctacaacttc tttactttct tttccaagtt cttttgcgat ttcgtacaat
     4921 cttttcttag acaaatcatg tcctcctctt ctattccata agagacctca ttttctttgt
     4981 aaatccagca tctgttacag ccaaaacctt tctcgatttc ccgactgcta tgcttaattc
     5041 cagtgttgaa aacacggtta caatttctac ttgataataa tgacttttat cttgaatctt
     5101 cttggtcaga ttgggtccag catcatgagc tagaaagacc aacttggcct tgccgtcttg
     5161 aatggccttg accaccaatt cttcacccga tatgatgcgc cctgctcgct gagcaagccc
     5221 caagagatta cttatctttt gcttattcaa gtcccaactc tcttcttttc actttgtgat
     5281 ccacataagc gatcaactcg tcataaaagc tttcttccac ttccatgcta aagctgcggt
     5341 taaagacctt cttctttttc gcctctaggg cttctgcatt gtctagtttg atataagcgc
     5401 cgcggccatt ggccttgccc gtaggatcaa taaagacttg tccttccttg ttcttgacaa
     5461 tgcggagcaa atcacgctta tcaatcactt cgttagacac aacagacttg cgcaaaggga
     5521 tttttcttgt tttcatcttt ccctcctcta gcagctttta ttcttctaca gtatcgtttt
     5581 ctacttccaa ctctactgaa gcagcgtctt ccatggcttc aaattcgcta gcagacttga
     5641 tatcgatacg gtaaccagtc aagtgagccg ccaagcgcac gttttgtcca cgacgaccaa
     5701 tggcaagaga aagcttgtta tctggaacaa ccaccaaggc acgtttgctg tcgttttcat
     5761 caaagataac ttggtcaacc tcagcaggag cgatggcatt gtagataaat tcagctggat
     5821 ctgctaccca ctcgataaca tcgatatttt cttcgattgg taccatgcgg tcatttttag
     5881 catcgtaacg agctgggtgg aatttgctag taatcttctt gatattagca ccaccacgtc
     5941 caacgattgt accgatagca tccacgtttg gattgtggct acgaacagca accttcgtac
     6001 ggtcacctgc ttcacgagcc acgctcatga tttcaacagt tccatcataa acttctggaa
     6061 tttcttgctc cattaaacgt ttgatcattt ctggatgact acggctaaca aagacgttca
     6121 caccacgagg gttgtcttca accttgtaaa cataaacttc gatacgatca tgagaagcaa
     6181 aaacttctcc aggaatttgg tcttgttttg acaattgggc ttcgatgcta ccaaggttga
     6241 catagataaa gcggttgtca aagcgttcta ctgtaccaga catgatttct tgctcatgtt
     6301 ctttgtaagt attgtaagtg atggcacgtg tttgcttgcg cattttttcc atgatggttt
     6361 gtttggcaga ctgggctgct acacgaccaa actcagctgg tgcttcttca aacttgattt
     6421 tgtctccaag ttcataagct gaattaatgg caagagcatc tttcaagctg atttccaaac
     6481 ggctatcaaa tacttcatca acaacttcac ggacagtata aactgtaaag tcacctgttt
     6541 tttcgttgaa gtcaatagct acgctgtctg actgaccata gcgtctgcga taagcggaac
     6601 gaagcgactc tactactgcg tcgatgatat cttctttttt gattcccttg tcttcttcca
     6661 aaatgcggaa ggcctctagc atttctttac tcatgttttc ttcacttttg aatcctcaaa
     6721 agctatcctt tctttttcta taatttaact gctaaacgtg cttttgatac taaactgtat
     6781 ggaatttgga cggttttctt acgcgtcttg tccatatatt ccatagtcaa cccgtcctct
     6841 tcgaaggcca acaaggttcc ttcaaagacc ttttgcttat cgatggcttg gtagagcccg
     6901 acatggatgt attttccaac cgctccagcg acggcatcct tggttttcaa agggcgttcc
     6961 aaacctggac tggtaatttc taggaaatat tgttctggga agggatctgg cttgatggtg
     7021 tctaggacag gactgataat ttctgtcaag tctgccgtgt cgttcaaggt aattccttcg
     7081 ggtttatcta caaaaatact gagaatcatg tcactgccaa tctttccata ctcgatatcc
     7141 acgagttcaa aaggagcttc tatgacaggt tctacaactt ctctgactaa ttctacgatt
     7201 gttgcgattg cgtccacctc ctcataagca agaggcgaag atatttcccc gcctcacttt
     7261 tcatattctt actatcagta tagcacgttt gccaacttat gtaaagcaaa agcacttgta
     7321 cagcctaatt ttaggctatc tcttaaaatt ctgcctcaac tcggtagata acttgcccct
     7381 tgtttgagaa tttttgctcg tattctgtca tgacattgcc ttcaaaatca ctggcatgca
     7441 aatctaacca gacaccattg agtttcatgc catattgaga aaagctcact aaactgtact
     7501 caaacaagcc acggttatcc gtcttgaaat gaatttctcc attttcaggc aagatacgtt
     7561 tgaaggtatc caagaaggtc ttgtaggtca aacgacgctt ttcatggcgt tttttcggcc
     7621 atggatctga aaagttcaga tacaagcgat caatctcacc gtcttcaaaa tagtcagtta
     7681 agtcagaacc atctacccac aagagcttga tgttaggcac tccaacttca agcaccttgt
     7741 ccaaagcgta gctcaaaaca gacttttgaa tatcaatccc gatatagttg atgtcagggt
     7801 tttgcttggc catacctgaa acaaaggcac cctttccact tccaacttcc acatgaatgg
     7861 gattatcatt gccaaacaag tcccgccatt ttgccttggc ttccaaggga ttgaggacca
     7921 catactgggg atttgcctct agtaattctg ttgccccttt acgatttcta actctcatct
     7981 tctctttcca tacttgtctc ggaaatgacg caaaccatga atctcccgat tgacattttc
     8041 taaatcttgg ttcatataat acttggaaat ctgactcaaa taagacaatt gaccatacca
     8101 atacaattta cttaataccg tttgattgta cttgtaaccg tagtaggtca accattcctt
     8161 ccactgatgt tctgaaatat aatggcagag catatgggcc acatcaaaca tgcgatcggt
     8221 caagcgaacc gaatcccaat ctactaaata aatcaagcca ctatctgtct caatccaatt
     8281 actatgtcgt acatctccat ggacaatggt cgcatggtcc tctctaaatc ctggaatagt
     8341 ctgacgtaaa tcagccatca cttcactgat aaaatgattt ttacgcaaag catctggagc
     8401 cgtttcctgc caagactgga gtaaatctac aggtgtttcc atggcatagc ccaaacgact
     8461 caattgtgtc atcaacggac gtgagcgatg aagacgggtt aaaatattga cgatttgctt
     8521 acgattcata tcataggggg tcaatatctt gcctgtcaac cattcttgag cacacatatc
     8581 acgcccatct gccaaacgac gactccataa taattgtgga gcaatttgtt ctctagctag
     8641 accaggtagg attggagagg tgttcatttt tacaaagatg cgcttcccgt caggatagct
     8701 acccatataa gccttgccac ttttcccagg tatgggagtc agtgttagct cattatcacc
     8761 caaatccatt tctttcctcc gtataaagtt tccttactat tctactagtt tttggcctat
     8821 tcgtcaacca ctctaacccg attctcaaag aaaagcctct ggattggctt gggtatcatt
     8881 atagcttgaa aaaggtaagc accatcttct gcttaccttt tcataatttt tataaataat
     8941 ataggagtgg ccaactgttg taaaacatgt ggactagagt agaaacccat aggttttgac
     9001 tctttttata agcaaagccc agcaacaaac ccccaagtag ataaaaaata aacgaaggga
     9061 cattagaagg tccatgcatg aaagaaaaga gagaggaagt tagcacaagc cctaaccaag
     9121 aattgtcaaa aaccgcacct tgaagaagtc ctctgaaaat gagttcctcc tggatggggc
     9181 caaaaactga ggtagtcaaa atcaaagaca gggaaattcc tctgctgact tccgccaagt
     9241 gttggacccc tgagccagaa gaaacagcga agaaatgaat ataaaccagc gtctcaagta
     9301 cacttagaag aaagattgca atgaaaagca aaagttgttt cttgcttaac atcccaaaag
     9361 aaatcatttc aaactttcta gcataagcaa cactcagcga ggttacaaga agacttacaa
     9421 gaatcaatgc agattcattt tgaaaaaaac ccccatggtt aatcgtataa ggaactgtaa
     9481 tgacaattat tagtactaaa aatccaaaac acaaggcatg aaatttatca aaaaactcca
     9541 taaaactatc ctcctcacca aacagacttc ctacgcgtca ttctttagtt ctagcctttc
     9601 caaaacaaac cattttatac tcttcgaaaa tcaa
//
LOCUS       DBEJHE010000050         9439 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC4 isolate 671759
            SAMN38261586-rid24793303.denovo.50, whole genome shotgun sequence.
ACCESSION   DBEJHE010000050 DBEJHE010000000
VERSION     DBEJHE010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261586
            Sequence Read Archive: SRR26833752
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 9439)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9439)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576136.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576136.1
            Genome Coverage       :: 109x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 19:48:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,067
            CDSs (total)                      :: 2,029
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 131
            CDSs (without protein)            :: 131
            Pseudo Genes (ambiguous residues) :: 0 of 131
            Pseudo Genes (frameshifted)       :: 64 of 131
            Pseudo Genes (incomplete)         :: 59 of 131
            Pseudo Genes (internal stop)      :: 46 of 131
            Pseudo Genes (multiple problems)  :: 32 of 131
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9439
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261586-rid24793303.denovo.50"
                     /strain="GPSC4"
                     /isolate="671759"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(80..883)
                     /locus_tag="ACL3EZ_001912"
     CDS             complement(80..883)
                     /locus_tag="ACL3EZ_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HGR0393432.1"
                     /translation="MQPTYNIDNPNLSYEAKRDLWRIGFGLQKVDNLVPSAYMESLAE
                     KQSRGELTYEQVYEDATAYHHTIDASTEEADLVSLRIVELLSRRGFSFSPATLLAIHK
                     ELFQDIFEPSIPVGQFRQTNITKNEPVLNGESVVYSDYSMIQMTLDYDFNQEKQVAYA
                     TLTQADVVKQIQHFISGIWQIHPFREGNTRTVTVFLIQYLREFGFDIDNIPFQQHSKY
                     FRDALVLDNAKILQRRPEFLTAFFENLLLGGQNDLSSEKMYLDLDLDFS"
     gene            complement(1164..1919)
                     /locus_tag="ACL3EZ_001913"
     CDS             complement(1164..1919)
                     /locus_tag="ACL3EZ_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3883 domain-containing protein"
                     /protein_id="HGR0393433.1"
                     /translation="MSKHPHYELLNLIGYGLAKFDKLFIKEFQCFSKSEFYRYVVSLG
                     IAETTGVVKNRMDLFDPYFDNNRKGWWQKAEVYRFRKDLIDMMFGNEDVHSYAEIVKM
                     LLASEGKKTGITIVEKPIVRTKFKRLQETGMEAENYFILHFDKEEKFQGGQLTDARLY
                     GDGYDFQVDVQEYSYLAEVKGIRKSKGRVRLTAKEFEKVKEFQSDFILSLVTNLDDIP
                     KLVLIDNPLKHFEFKKNIIKNEIIEYRSVEDLY"
     gene            complement(1989..4640)
                     /locus_tag="ACL3EZ_001914"
     CDS             complement(1989..4640)
                     /locus_tag="ACL3EZ_001914"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009732359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0004832 - valine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006438 - valyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HGR0393434.1"
                     /translation="MSKELSSKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIP
                     PPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLRGEG
                     ITRYDLGRESFLTKVWEWKDEYATTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVF
                     VDLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALEVAT
                     TRPETMFGDVAVAVNPEDPRYKDLIGKNVILPIANKLIPIVGDEHADPEFGTGVVKIT
                     PAHDPNDFLVGQRHNLPQVNVMNDDGTMNELAFEFSGMDRFEARKAVVAKLEEIGALV
                     KIEKRVHSVGHSERTGVVVEPRLSTQWFVKMDQLAKNAIANQDTEDKVEFYPPRFNDT
                     FLQWMENVHDWVISRQLWWGHQIPAWYNADGEMYVGEEAPEGDGWTQDEDVLDTWFSS
                     ALWPFSTMGWPEVDSEDFKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRQPFQNVL
                     IHGLIRDEQGRKMSKSLGNGIDPMDVIEKYGADALRWFLSNGSAPGQDVRFSYEKMDA
                     SWNFINKIWNISRYILMNNGGLTLDVAHDNVTKVATGEAGNVTDRWILHNLNETIAKV
                     TENFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEEEKVITRSVLLYTLDKI
                     LRLLHPIMPFVTEEIFGQISEGSIVTAAYPTVNLAFEDLAAHTGVESLKDLIRAVRNA
                     RAEVNVAPSKPITILVKTSDSDLEAFFNSNVNYIKRFTNPEHLEIASTIPAPELAMSS
                     VITGAEIFLPLADLLNVEEELARLDKELAKWQKELDMVGKKLSNERFVANAKPEVVQK
                     EKDKQADYQAKYDVTVARIDEMKKLVK"
     gene            complement(4652..5614)
                     /locus_tag="ACL3EZ_001915"
     CDS             complement(4652..5614)
                     /locus_tag="ACL3EZ_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-binding factor A"
                     /protein_id="HGR0393435.1"
                     /translation="MSDVKEEVSSLSEKQLRQIDVEYAELNDSDIIERLAYLEINNNE
                     KRIVISDIEPTKEIMSVSDQIFEIQKNFQKIKNMFELFISDVSDFLSIKNKLESKELE
                     IEEADVNRFMIHLLSSGKLFVDFNENQIKQKYSKDSEEFDCIHGFASYQYDTNFAYRF
                     CHSLRNYSQHTDLPINEVKAVSPDDETVIIDFYIDLDYLLNSNFKWKKLKGELIKLNQ
                     ETSKIDAIALVKEYFNALTELYGNYNKLFLKLNHNTLVDIKSKLESLKLKHSRYYISK
                     ISKYDLKYNPGNYTMSPLAAFAEIEEIYIELSKIGLVKIVNKSN"
     gene            complement(5616..6173)
                     /locus_tag="ACL3EZ_001916"
     CDS             complement(5616..6173)
                     /locus_tag="ACL3EZ_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000124554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family protein"
                     /protein_id="HGR0393436.1"
                     /translation="MARTELPDQIETERLVLRVRTVADAEDIFDYASLPEVAYPAGFP
                     PVKTLEDEIYYLEHILPERNQKENLPAGYGIVVKGTDKIVGSVDFNHRHEDDVLEIGY
                     TLHPDYWGRGYVPEAARALIDLAFKDLGLHKIELTCFGYNLQSKRVAEKLGFTLEARI
                     RDRKDAQGNCCDSLIYGLLKSEWEE"
     gene            complement(6160..6609)
                     /locus_tag="ACL3EZ_001917"
     CDS             complement(6160..6609)
                     /locus_tag="ACL3EZ_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase"
                     /protein_id="HGR0393437.1"
                     /translation="MIGVVARENAAEQIKQYQKFTVNISDETSMLAMEQAGFISHQEK
                     LERLGVHYEISERTQTPILDACPLVLDCRVDRIVEEDGICHIFAKILERLVAPELLDE
                     KGHFKNQLFAPTYFMGDGYQRVYRYLDKRVDMKGSFIKKARKKDGKN"
     gene            complement(7022..7417)
                     /locus_tag="ACL3EZ_001918"
     CDS             complement(7022..7417)
                     /locus_tag="ACL3EZ_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HGR0393438.1"
                     /translation="MSKKLNRKKQLRNGLRRAGAFSSTVTKVVDETKKVVKRAEQSAS
                     AAGKAVSKKVEQAVEATKEQAQKVANSVEDFAANLGGLPLDRAKTFYDEGIKSASDFK
                     NWTEKELLALKGIGPATIKKLKENGIKFK"
     gene            complement(7513..7767)
                     /locus_tag="ACL3EZ_001919"
     CDS             complement(7513..7767)
                     /locus_tag="ACL3EZ_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1912 family protein"
                     /protein_id="HGR0393439.1"
                     /translation="MSYEQEFMKEFEAWVNTQIMINDMAHKESQKVYEEDQDERAKDA
                     MIRYESRLDAYQFLLGKFENFKAGKGFHDLPEGLFGERNY"
     gene            complement(7777..9111)
                     /locus_tag="ACL3EZ_001920"
     CDS             complement(7777..9111)
                     /locus_tag="ACL3EZ_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000752887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF438 domain-containing protein"
                     /protein_id="HGR0393440.1"
                     /translation="MADERIHVLRDILLELHNGASPESVQERFDATFAGVSAIEISLM
                     EHELMNSDSGVTFEDVMELCDVHANLFKNAIKGVEVSDTEHPGHPVRVFKEENLALRA
                     ALIRIRRLLDTYESMEDEEMLAEMRKGLVRQMGLVGQFDIHYQRKEELFFPIMERYGH
                     DSPPKVMWGVDDQIRELFQTALTIAKSLPEVSISSVKEAFEAFATEFESMIFKEESIL
                     LMILLESFTQDDWLQIAEESDAYGYAIIRPSEKWVPERQSFIEEKIAEEPVQLDTAEG
                     QVQQVIDTPEGHFTITFTPKEKEAVLDRHSQQAFGNGYLSVEQANLILNHLPMEITFV
                     NKDDIFQYYNDNTPADEMIFKRTPSQVGRNVELCHPPKYLDKVKTIMKGLREGTKDKY
                     EMWFKSESRGKFVHITYAAVHDEDGEFQGVLEYVQDIQPYREIDTDYFRGLE"
     gene            complement(9111..9344)
                     /locus_tag="ACL3EZ_001921"
     CDS             complement(9111..9344)
                     /locus_tag="ACL3EZ_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006144975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1858 domain-containing protein"
                     /protein_id="HGR0393441.1"
                     /translation="MDNIIDVSIPVAEVVDKHPEVLEILVELGFKPLANPLMRNTVGR
                     KVSLKQGSKLAGTPMDKIVRTLEANGYEVIGLD"
BASE COUNT         2701 a         2110 c         1749 g         2879 t
ORIGIN      
        1 aactttgatg atatacgttt tcttgtgaga atatttactt cattttttcc taaaattcaa
       61 tgtttactca gtatttggat tatgaaaaat cgaggtctaa atctagatac attttttctg
      121 aagacaaatc attttgacca ccgagcaaga gattttcaaa aaaagctgtt aaaaactcag
      181 gacgtcgctg taaaatcttt gcattatcta ataccaaggc atcacgaaaa tacttggaat
      241 gttgctgaaa tggtatatta tcaatatcaa aaccaaactc acgaagatac tgaatcaaaa
      301 agaccgttac tgtccgagtg tttccttcgc gaaatggatg aatctgccag attcctgaaa
      361 taaaatgctg gatttgttta accacatccg cctgagttag tgtcgcatat gcaacttgtt
      421 tttcctgatt aaaatcataa tctaaggtca tttgaatcat ggagtaatca gagtacacaa
      481 cactttcacc attcaaaaca ggttcattct ttgtgatatt ggtctgacga aattgcccca
      541 ccggaataga gggttcaaat atatcttgaa acaactcctt atgaatagca agtaaggtcg
      601 caggactaaa gctaaagcct cttcgagaca atagttctac aatacgtaga gaaaccaagt
      661 ctgcctcttc cgtacttgca tcaatagtat ggtgataagc cgttgcatcc tcataaacct
      721 gctcataagt cagttctccc cgggactgtt tctcagccaa agattccata tacgctgatg
      781 gcactagatt gtcaactttc tgcagaccaa aacctatccg ccataaatca cgcttcgctt
      841 cataagacaa gtttggattg tcaatgttgt aagttggttg catagaaata tcctttcaat
      901 tgtttttctt cattaccagt aaatcacgaa attggttgga aactggctta aactataaaa
      961 agtcctcaca ataggttcta tgatatatat atatatatac ttcatgtaaa taataaaaga
     1021 gttataatca gcactactga taaattcaat accgatttcg ccatcttaaa acttagtcaa
     1081 acgaataccg ttgatttcca gttcattaag tcgttgacct gtcaagactt ctcgttcctt
     1141 caactggaaa agttaagggg gaactaatac aaatcctcta cgcttctata ttcaatgatt
     1201 tcatttttga taatattctt tttaaactca aaatgtttta aaggattatc gattaacact
     1261 aactttggaa tatcatctag atttgtgacc aaggataaaa taaaatccga ttgaaactcc
     1321 ttgacttttt caaattcttt tgcagttaaa cgcacacgcc ccttagattt tcggatacct
     1381 tttacttcgg caaggtaaga atactcttgg acatctacct gaaagtcata tccatcacca
     1441 taaagacggg catcggttaa ctgtccacct tggaattttt cttctttatc aaaatgaagg
     1501 ataaaataat tctcagcctc cattcccgtt tcctgtagac gtttgaattt agttcgaact
     1561 attggttttt caacgatggt tatgcctgtt ttcttccctt cactggcaag taacatttta
     1621 actatttcag cataactatg aacatcttca tttccaaaca tcatatcaat taaatcttta
     1681 cgaaaacgat aaacttcagc tttctgccac caaccttttc gattattgtc aaaataagga
     1741 tcaaataaat ccattctatt ttttacaact ccagttgttt cagcaattcc cagagaaacc
     1801 acatagcgat aaaactccga cttgctaaag cattgaaatt cttttataaa aagcttgtca
     1861 aacttggcaa gaccgtagcc aattaaattt aacaattcat aatgagggtg tttggacatc
     1921 actttctcca tcaatagata ttgatttcat tataccaaaa aacacggctc atcaccgtgt
     1981 ttctgtgttt atttcaccaa cttcttcatc tcatcaatac gtgctacggt cacatcatac
     2041 ttggcttggt agtcggcttg tttgtctttt tctttttgga caacttctgg tttagcgttg
     2101 gcgacgaagc gttcgttaga gagtttctta ccaaccatgt ccagttcttt ttgccattta
     2161 gcgagttctt tgtcgagacg agctagttct tcttcaacat tgaggagatc ggccagtggc
     2221 aagaagattt cggctcctgt aataacgctt gacatagcca gttcaggtgc agggatggtt
     2281 gatgcgattt ccaagtgttc tggatttgta aagcgtttga tatagttgac attgctgtta
     2341 aagaaggctt ccaagtcact atcgcttgtc ttaacaagga tggtgatagg cttgcttggt
     2401 gctacattta cttccgcacg cgcattccga acagcacgaa ttaagtcttt gagactttcc
     2461 acaccagtgt gagccgcaag gtcttcaaag gctagattaa cagttgggta tgcagctgtc
     2521 acgatagaac cttctgagat ttgtccaaag atttcctctg tcacgaatgg catgattggg
     2581 tgaaggagac gaaggatctt gtccaaagtg tatagtagaa cagaacgtgt gatgactttc
     2641 tcttcttcgt tatcgctata aaggacttcc ttggtcaact caacatacca gttggcaaat
     2701 tcttcccaaa tgaagttgta aaggatatga ccagccacac caaactcgaa cttatcaaag
     2761 ttttcagtaa cttttgcaat ggtttcgttg agattgtgga gaatccagcg gtccgtcaca
     2821 ttaccagcct cacctgttgc aacttttgtg acattgtcat gcgccacatc cagcgtcaaa
     2881 cctccattgt tcatgaggat atagcgagaa atgttccaaa tcttgttaat aaagttccat
     2941 gaagcatcca ttttctcata agagaaacgc acgtcttgtc ctggcgcaga accgtttgaa
     3001 aggaaccatc gaagggcatc ggcaccgtat ttctcgataa catccattgg gtcaatcccg
     3061 ttaccgagag acttagacat cttgcgtcct tgctcgtcac gaatgagacc gtggataagg
     3121 acgttttgga atggttgacg gcctgtgaat tccaatgact ggaagatcat acgagacacc
     3181 cagaagaaga tgatgtcgta acctgttacc aaggttgaag ttgggaaata acgtttaaag
     3241 tcttctgagt cgacttcagg ccagcccatg gttgaaaatg gccagagggc agaactgaac
     3301 caagtatcca agacgtcttc gtcctgagtc catccgtcac cttctggagc ttcttcgccg
     3361 acatacattt caccatcagc attgtaccag gcagggattt ggtgacccca ccaaagctga
     3421 cgagagataa cccagtcgtg gacattttcc atccattgaa ggaaggtatc gttgaaacga
     3481 ggtgggtaga attcgacctt gtcctctgtg tcttggttgg caatggcgtt cttagccaat
     3541 tggtccatct tgacgaacca ttgagtagac aagcgtggct caactacgac acctgtccgt
     3601 tctgagtgac cgactgaatg gacacgtttt tcgattttga caagggcacc gatttcttcc
     3661 aacttagcaa cgactgcctt acgagcttca aaacgatcca tgcctgaaaa ttcaaaggca
     3721 agctcattca tagttccgtc gtcgttcatg acgttgactt gtggcaagtt atgacgttgg
     3781 ccaaccaaga agtcatttgg atcgtgggca ggtgtgattt tcacgacacc agtaccaaac
     3841 tcaggatctg cgtgctcatc tccaacgatt gggatgagtt tattagcgat tggaaggatg
     3901 acgtttttac caatcaagtc cttgtagcgc gggtcttctg gattaaccgc aaccgcaacg
     3961 tccccaaaca tagtctcagg acgagttgta gcaacttcaa gggcgcgtga accatcttcc
     4021 agcatgtaat tcatgtggta gaaggcacct tctacatcct tgtgaatcac ctcaatatca
     4081 gaaagggctg tgcgagctgc tgggtcccag ttgatgataa actcaccacg atagatccag
     4141 cctttcttgt aaaggtccac aaagacctta cgaacagctt ttgacaaacc ttcgtcaaga
     4201 gtgaaacgct cacgagaata gtctacagaa agccccatct tgccccattg ttccttgatg
     4261 gtagtggcat attcgtcttt ccattcccag accttcgtca agaaagactc acgacctagg
     4321 tcataacgcg taataccctc accacgtaag cgctcctcaa ccttagcctg agtcgcaata
     4381 ccagcgtggt ccatacctgg aagccaaagg gtatcaaagc cctgcatgcg tttttgacgg
     4441 atgatgatat cctgcaaagt cgtatcccaa gcgtgaccaa ggtgaagttt cccagttacg
     4501 tttggtggtg gaatcacgat tgaataaggc ttagcctttt gatcgcctga aggcttgaaa
     4561 acatccgcat caagccattt ttggtaacga ccagcctcaa cctcggctgg attgtattta
     4621 gatgaaagtt ctttagacat gtgtgttctc cttaattact tttattgaca attttaacca
     4681 aaccaatttt tgaaagttca atataaatct cttcaatttc agcaaatgct gcaagtggtg
     4741 acatagtata atttccagga ttatatttaa gatcatactt gcttatcttt gaaatataat
     4801 acctagagtg tttcaatttt aatgattcca actttgattt aatatctact aatgtattat
     4861 ggtttaactt taaaaacaac ttattataat taccatagag ctctgtaaga gcattaaagt
     4921 attctttcac tagagctata gcgtcaatct tagatgtttc ttggtttagt tttatcaact
     4981 cccctttcaa ttttttccat ttaaagttgg aatttaaaag ataatctaaa tcaatataga
     5041 aatctattat aacagtctca tcatctgggc taacagcttt tacctcattt attggtaagt
     5101 cagtatgttg cgaataattt ctcaaagaat ggcaaaatcg ataagcaaaa ttggtatcat
     5161 actgatagct tgcaaaacca tgtatacaat caaactcctc actatctttg gaatattttt
     5221 gtttaatttg gttttcgtta aaatcgacaa acaattttcc actggataat aaatgaatca
     5281 tgaaacgatt tacatctgcc tcttcaattt ctaattcctt tgactcaagt ttatttttaa
     5341 tacttaaaaa atccgagaca tctgaaataa acaattcgaa catattcttg attttttgaa
     5401 aattcttttg aatctcaaaa atttggtccg agactgacat tatttccttg gttggttcaa
     5461 tatcagagat gacaatacgt ttttcattgt tgttaatttc taaataagct aatcgctcga
     5521 taatatcact atcatttaat tcagcatact caacatcaat ttggcgtaac tgcttctcag
     5581 atagagagct tacttcctct tttacatcgc tcatcttatt cctcccactc gctcttcagc
     5641 aagccatata tcagactgtc acagcagttg ccttgagcat ctttgcggtc tcttatgcga
     5701 gcttcgaggg taaagccaag cttttccgcg actcgtttac tttgaaggtt atatccaaag
     5761 caagttagtt caatcttgtg aagacccaaa tctttaaagg ctaagtcaat caaggcacgc
     5821 gcagcttctg gcacataacc tcgcccccaa tagtctgggt gtaaggtata gccgatttcc
     5881 agcacatcat cttcatggcg atggttgaaa tcgacagagc caacgatctt atccgttcct
     5941 ttgacgacaa tcccgtagcc tgctgggaga ttttcctttt gattacgctc cggaagaatg
     6001 tgctccagat aataaatctc atcttccaag gtcttgactg gaggaaaacc tgctggatag
     6061 gcgacctctg gcaaactagc atagtcaaag atatcctcag catccgccac agtacggact
     6121 cgtaaaacga gacgttctgt ttcgatttga tctggcagct cagttcttgc catccttctt
     6181 cctcgctttt ttgatgaaac tgcccttcat atctacacgc ttatccagat agcgataaac
     6241 gcgctgatat ccatctccca tgaaataggt tggggcaaac agttgatttt taaaatgtcc
     6301 cttttcatcc aggagttctg gggcaacaag tcgctcaaga atcttggcaa agatgtggca
     6361 aataccgtct tcctcaacaa tcctatctac cctacaatct aaaacaagtg gacaggcgtc
     6421 taaaatagga gtctgagttc gttcagaaat ttcataatgc actcccaaac gttccaattt
     6481 ctcctgatga ctgataaaac cagcctgctc catcgcaagc atagaagttt catcagaaat
     6541 attcacagta aatttttgat actgtttgat ctgctctgcg gcattctctc tcgcaacgac
     6601 tccaatcaca acccaatctc ctagactata agaggaacta caggtcgtga tgttatagcc
     6661 aaaattctaa tcttgatatc ctaaaataaa aacaggaaaa ccataatata gtttacttgt
     6721 gttaaaagat tgcttcataa caaccccctt tgactaagac gtaaaagaaa agccctgcca
     6781 tctacatgac agggacgaat gtgtttatcc gcggtaccac ccaatttcgg gcagttgccc
     6841 gcaactctcg tctttaaagc aaaaagacac ttttatttca ttttttcagt cattagcaac
     6901 cagttttgac acatttgtgg acttctcagc gccgccactt tctgtaaaat gtgggattca
     6961 aaacacctct aatggctcta ttgtagcaag tttttctcgg aaatgcaagg ctcaagaaaa
     7021 attacttgaa cttgatgcca ttttctttca atttcttgat ggtagctggg ccgattcctt
     7081 tcaaggcaag gagttctttt tcagtccagt ttttgaaatc tgaagcagac ttgattcctt
     7141 catcatagaa agtcttggca cgatcaagtg gaagtccacc caagtttgct gcaaaatctt
     7201 ctacagaatt agctactttt tgagcttgct ctttggtagc ttctactgct tgttcaactt
     7261 ttttagaaac agccttacca gctgcgcttg ctgactgttc tgcacgcttc acgacttttt
     7321 ttgtctcatc tacaacctta gtcacagtac ttgaaaaggc acctgcgcga cggaggccat
     7381 ttcgtaattg ttttttacga ttgagtttct ttgacatgat aaaatccttt caataaaaaa
     7441 tccctgctct gacaaggatt taacataaac attctatcaa gattttagtg aaaaatcaag
     7501 aatctttctc gtttaataat ttcgctcacc aaacaagcct tctggcaaat catggaatcc
     7561 cttgcctgct ttgaagtttt caaacttacc aagcaagaac tgataagcat ccaagcgact
     7621 ctcgtagcga atcatggcat ctttggcacg ctcgtcctgg tcttcttcgt aaactttttg
     7681 actttccttg tgcgccatgt cgttaatcat gatttgggta ttgacccaag cttcaaattc
     7741 cttcataaat tcttgttcgt aactcatttt ttctccttat tctaatccac gaaaatagtc
     7801 cgtatcaatc tcacggtagg gctggatatc ctgaacatac tccaacactc cttggaattc
     7861 tccgtcttca tcgtgtactg cagcataggt gatgtggaca aacttacctc gcgactcaga
     7921 cttgaaccac atttcatact tgtccttggt cccctcacga agccccttca tgatagtttt
     7981 gaccttgtcc aagtacttag gcggatggca gagttcgaca ttgcgcccga cttgagacgg
     8041 cgtccgtttg aaaatcatct catcagctgg cgtattgtca ttgtaatact ggaaaatatc
     8101 atctttattg acaaaggtaa tctccatagg gaggtgattg aggatgagat tggcctgctc
     8161 gactgaaaga tagccattac caaaagcctg ttgactatgg cggtccagca cagcttcctt
     8221 ttccttaggg gtaaaggtaa tggtaaaatg gccttctggc gtatctatga cttgttgaac
     8281 ttgaccttct gccgtatcta gctgtacagg ctcctctgca atcttttcct caataaagct
     8341 ctgtcgttct ggcacccatt tctctgacgg acggatgatg gcatagccat aggcatcgct
     8401 ctcctccgca atctgaagcc agtcatcctg agtaaaagac tcaaggagaa tcatgaggag
     8461 gatggactct tccttgaaaa tcatactttc aaactctgtc gcaaaagctt caaaagcttc
     8521 ctttacactg ctaattgaca cttctggtag tgacttggct atcgttagag ctgtttgaaa
     8581 gagttcccta atctgatcat ccactcccca cataactttg ggaggtgaat cgtgtccata
     8641 gcgctccatg ataggaaaga agagttcttc cttacgttgg taatggatgt caaattgacc
     8701 cacaagtccc atctgacgca ccaaaccctt acgcatctcc gccagcattt cctcgtcttc
     8761 catagactca taggtatcta acaatctacg aatgcgaatc aaggccgcac ggagagccag
     8821 attttcttct ttgaagacac gaactgggtg acctggatgc tcagtatctg aaacttcgac
     8881 acctttgata gcatttttaa aaagattggc atggacatca cagagttcca taacatcttc
     8941 aaaggtgaca cctgagtctg agttcatcag ctcgtgctcc ataagggaaa tctcaatggc
     9001 tgagacaccc gcaaaggtcg catcaaaacg ctcctgaacc gactcaggag aggcgccatt
     9061 atgcaattct aataaaatat cccgtaggac atgaatccgt tcatctgcca ttagtctaat
     9121 ccaatcactt cgtagccatt cgcttccagt gtgcgtacaa tcttgtccat aggagttcct
     9181 gctagcttag aaccttgttt aagtgatact ttacgaccaa ctgtattgcg catcaaggga
     9241 ttggcaaggg gtttaaaacc cagctccact agaatttcca agacttctgg atgcttgtcc
     9301 accacttctg caacaggaat tgacacatcg atgatattgt ccatgacgac ctccattata
     9361 tgttctaata ctcaatgaaa atcaaagagc aaactagaaa gctagccgca ggttgctcaa
     9421 aacagtgttt tgaggttgt
//
LOCUS       DBEJHE010000051         7487 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC4 isolate 671759
            SAMN38261586-rid24793303.denovo.51, whole genome shotgun sequence.
ACCESSION   DBEJHE010000051 DBEJHE010000000
VERSION     DBEJHE010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261586
            Sequence Read Archive: SRR26833752
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 7487)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7487)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576136.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576136.1
            Genome Coverage       :: 109x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 19:48:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,067
            CDSs (total)                      :: 2,029
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 131
            CDSs (without protein)            :: 131
            Pseudo Genes (ambiguous residues) :: 0 of 131
            Pseudo Genes (frameshifted)       :: 64 of 131
            Pseudo Genes (incomplete)         :: 59 of 131
            Pseudo Genes (internal stop)      :: 46 of 131
            Pseudo Genes (multiple problems)  :: 32 of 131
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7487
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261586-rid24793303.denovo.51"
                     /strain="GPSC4"
                     /isolate="671759"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(<1..450)
                     /locus_tag="ACL3EZ_001922"
     CDS             complement(<1..450)
                     /locus_tag="ACL3EZ_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001856457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
                     /protein_id="HGR0393442.1"
                     /translation="MEQLHFITKLLDIKDPNIQILDIINKDTHKEIIAKLDYEAPSCP
                     DCGSLMKKYDFQKPSKIPYLETTGMPSRILLRKRRFKCYHCSKMMVAETPLVKKNHQI
                     PRIINQKIAQKLIEKISMTDIAHQLAISTSTVIRKLNDFHFECNFRNL"
     gene            complement(632..931)
                     /locus_tag="ACL3EZ_001923"
     CDS             complement(632..931)
                     /locus_tag="ACL3EZ_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HGR0393443.1"
                     /translation="MMNMQNMMRQAQKLQKQMEQSQAELAAMQFVGKSAQDLVQATLT
                     GDKKVVSIDFNPAVVDPEDLETLSDMTVQAINSALEQIDETTKKKLGAFAGKLPF"
     gene            1333..2037
                     /locus_tag="ACL3EZ_001924"
     CDS             1333..2037
                     /locus_tag="ACL3EZ_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004241810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YoaK family protein"
                     /protein_id="HGR0393444.1"
                     /translation="MGGKMRLLPIRKISRQSKRLALFLMFCAGYVDAYTFIVRGNTLV
                     AGQTGNVVFLSVELIKNNVSDVRDKVLTLLAFMMGVFLLTIYKEKLRIVKKPILSLIP
                     LAILSIIIAFVPQTVDNIYLVPPLAFCMGLVTTAFGEVSGIAYNNAFMTGNIKRTMLA
                     FGDYFRTKHTPFLREGFIFVSLLSSFVLGVVFSAYLTIFYHEKTILGVPIMMSVFYLS
                     MLFASWQKKVKEKASF"
     misc_feature    2096..2183
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            2219..2533
                     /gene="rplU"
                     /locus_tag="ACL3EZ_001925"
     CDS             2219..2533
                     /gene="rplU"
                     /locus_tag="ACL3EZ_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HGR0393445.1"
                     /translation="MSTYAIIKTGGKQVKVEVGQAVYVEKLNVEAGQEVTFNEVVLVG
                     GENTVVGTPLVAGATVVGTVEKQGKQKKVVTYKYKPKKGSHRKQGHRQPYTKVVINAI
                     NA"
     gene            2549..2893
                     /locus_tag="ACL3EZ_001926"
     CDS             2549..2893
                     /locus_tag="ACL3EZ_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HGR0393446.1"
                     /translation="MIQAVFERAEDGELRSAEITGHAESGEYGLDVVCASVSTLAINF
                     INSIEKFAGYEPILELNEDEGGYLMVEIPKDLPSHQREMTQLFFESFFLGMANLSENY
                     SEFVQTRVITEN"
     gene            2910..3203
                     /gene="rpmA"
                     /locus_tag="ACL3EZ_001927"
     CDS             2910..3203
                     /gene="rpmA"
                     /locus_tag="ACL3EZ_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HGR0393447.1"
                     /translation="MLKMTLNNLQLFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVTG
                     GSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPIAK"
     gene            complement(3529..3677)
                     /locus_tag="ACL3EZ_001928"
                     /pseudo
     CDS             complement(3529..3677)
                     /locus_tag="ACL3EZ_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000617844.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
     gene            4156..5073
                     /locus_tag="ACL3EZ_001929"
     CDS             4156..5073
                     /locus_tag="ACL3EZ_001929"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003919 - FMN adenylyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HGR0393448.1"
                     /translation="MIITIPIKNQKDIGTPSDSVVVLGYFDGIHKGHQELFRVANKAA
                     RKDLLPIVVMTFNESPKIALEPYHPDLFLHILNPAERERKLKREGVEELYLLDFSSQF
                     ASLTAQEFFATYIKAMNAKIIVAGFDYTFGSDKKTAEDLKDYFDGEVIIVPPVEDEKG
                     KISSTRIRQAILDGNVKEAGKLLGAPLPSRGMVVHGNARGRTIGYPTANLVLLDRTYM
                     PADGVYVVDVEIQRQKYRAMASVGKNVTFDGEEARFEVNIFDFNQDIYGETVMVYWLD
                     RIRDMTKFDSVDQLVDQLKADEEVTRNWS"
     gene            complement(5166..6014)
                     /locus_tag="ACL3EZ_001930"
     CDS             complement(5166..6014)
                     /locus_tag="ACL3EZ_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000592058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HGR0393449.1"
                     /translation="MIKKIYPIFTILLGAAIYAFGLTYFVVPHHLFEGGATGITLITF
                     YLFKIPVSLMNLLINIPLFILAWKIFGAKSLYSSLLGTLALSAWLAFFEHIPLHIDLQ
                     GDLLITALIAGILLGIGLGIIFNAGGTTGGTDILARILNKYTHISIGKLLFILDFCIL
                     MLILLIFKDLRLVSYTLLFDFIVSRVIDLIGEGGYAGKGFMIITKRPDQLAKAINDDL
                     GRGVTFISGQGYYSKENLKIIYCIVGRNEIVKTKEMIHRIDPQAFITITEAHEILGEG
                     FTFEKE"
     gene            6155..6994
                     /locus_tag="ACL3EZ_001931"
     CDS             6155..6994
                     /locus_tag="ACL3EZ_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005504 - fatty acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HGR0393450.1"
                     /translation="MTKIKIVTDSSVTIEPELVKQLDITIVPLSVMIDNVVYSDADLK
                     EEGKFLQLMQESKNLPKTSQPPVGVFAEIFEDLCKDGGQILAIHMSHALSGTVEAARQ
                     GASLSTADVTVVDSSFTDQALKFQVVEAAKLAQEGKDMEAILSHVEEVKNHTELYIGV
                     STLENLVKGGRISRVTGLLSSLLNIRVVMQMKDHELQPMVKGRGTKTFKKWLDELITS
                     LSERAVAEIGISYSGSDDWAKEMKESLQAYVEKPISVLETGSIIQTHTGENAWAILIR
                     YHS"
     gene            7101..7376
                     /locus_tag="ACL3EZ_001932"
     CDS             7101..7376
                     /locus_tag="ACL3EZ_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HGR0393451.1"
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVEAVFAAVADYLAAGEKVQ
                     LIGFGNFEVRERAERKGRNPQTGKEMTIAASKVPAFKAGKALKDAVK"
BASE COUNT         2349 a         1235 c         1520 g         2383 t
ORIGIN      
        1 cagatttcta aaattacact caaagtggaa gtcattgagc ttgcgaatga cagttgaagt
       61 tgaaatggcc agctgatggg caatatcagt catagaaatt ttttcaatta acttttgagc
      121 aattttttgg ttgatgatac gagggatttg gtgatttttc tttaccaggg gagtctcagc
      181 aaccatcatt tttgaacagt gatagcactt gaaacggcgt tttctaagga gaattctaga
      241 aggcatacca gttgtttcga ggtaagggat cttagacggt ttttgaaagt catatttctt
      301 cattagactt ccacaatcag ggcaagatgg agcctcataa tccagcttag cgataatttc
      361 cttgtgtgta tccttattga tgatgtctaa aatctggata ttagggtctt taatgtctag
      421 taattttgtg ataaaatgta attgttccat atgaatcttt ctaatgagtt gtttggtcgc
      481 ttttcattat agatcttatg ggactttttt tctacaataa aataggctcc ataatatcta
      541 tagtggattt acccactaca aatattatag agtcattttt gcacctttct tagcctttgt
      601 tatcgacaag cattgttcta gctccttgtt tttagaaagg taatttccca gcgaaagcac
      661 ccagtttttt cttggtagtt tcatcgattt gttcaagagc agagttgatg gcttgaacgg
      721 tcatatcaga aagagtctca aggtcctctg ggtcaacgac agctggattg aaatcaatgc
      781 tgacaacttt cttatcgcca gttaaggtcg cttggacaag atcttgagca gatttgccaa
      841 caaattgcat agcagcaagt tcagcttggc tttgttccat ttgtttttga agtttttgtg
      901 cttgacgcat catgttttgc atgttcatca taagatttct aaagttcctt tcatctcaag
      961 gggataatcc ttgttgttaa caagtgcctg attttctctc ctaattgtta ttagtagcat
     1021 agccatcaag cccaagtatt gattttatta taccattttt ttaagacata gtcttttatt
     1081 ggtgagagtt atttatgtca aggagtgatt agaaataaat taaaataatg atttttgcta
     1141 agagggctct attctagttt catggaaatg attttactaa aggttcgtat gctttgtttg
     1201 caaacatgtt acatctatct atttttggat aaatagttgt ctattattat ttttatgcta
     1261 atagtaaaat ctaaatggta gcctacgatt ttttagaaag aaaatggtac aatatttcta
     1321 agagaaaata caatgggagg taaaatgagg ttattaccta taagaaaaat atcacgtcag
     1381 tctaaaaggt tagcactttt tttgatgttt tgtgctggat atgtggatgc ttacactttt
     1441 attgttcgcg ggaataccct tgtagctgga caaactggaa atgttgtctt tctttcagta
     1501 gaattaatta aaaataatgt ttcggatgtt agggacaagg ttctcacctt gctagcgttt
     1561 atgatgggag tctttttatt aacgatttat aaggaaaaat tgagaattgt gaaaaaacct
     1621 attctgtcct tgattccctt ggcaatctta tcaatcatta ttgcttttgt gccgcaaact
     1681 gtggataata tctatctagt gccgcccttg gccttctgta tgggactggt gacaactgct
     1741 tttggagaag tgtcgggtat tgcctataat aacgctttta tgacagggaa tatcaaacgg
     1801 accatgctgg cttttggaga ttatttccga accaagcaca ctcctttttt gcgtgaagga
     1861 ttcatatttg ttagcctgct tagtagtttt gtccttggcg ttgtcttttc agcctatttg
     1921 acgattttct atcatgaaaa gaccattctt ggtgttccta ttatgatgag cgttttttac
     1981 ctcagcatgc tttttgcctc ttggcagaaa aaagtaaaag aaaaagcttc attttaggtg
     2041 ttattacttg taagaaaata ggagatatgc tatacttgaa gagttgacta tgcacgatcc
     2101 tgtgcaaccg cacgaacatc gttgcttgat tattcaagtt taagtggttc gtcccacgat
     2161 gctaggcgag tcttcacaaa aaatcgggga aacccataaa aatcatagga ggtgcataat
     2221 gagcacatac gcaattatca aaactggcgg aaaacaagtt aaagttgaag ttggtcaagc
     2281 agtttacgtt gaaaaattga acgttgaagc tggtcaagaa gttactttta acgaagttgt
     2341 tcttgttggt ggtgaaaaca ctgttgtcgg aactccactt gttgctggag ctactgtagt
     2401 tggaactgtt gaaaaacaag gaaaacaaaa gaaagtggtt acttacaagt acaaacctaa
     2461 aaaaggtagc caccgtaaac aaggtcaccg tcaaccatat acaaaagttg tcatcaacgc
     2521 aatcaacgct taattttaag gagaacacat gatacaggca gtctttgaga gagccgaaga
     2581 tggcgagctg aggagtgcgg aaattactgg acacgccgag agtggcgaat acggcttaga
     2641 tgtcgtgtgt gcatcggttt ctacgcttgc cattaacttt atcaattcta ttgagaaatt
     2701 tgcaggctat gaaccaatcc tagaattaaa cgaagatgaa ggtggctatc tgatggttga
     2761 aataccaaaa gatcttcctt cacaccagag agaaatgacc cagttattct ttgaatcatt
     2821 tttcttaggt atggcaaact tatcggagaa ctattctgag ttcgtccaaa ccagagttat
     2881 cacagaaaac taacacggag gaaaacatta tgttaaaaat gactcttaac aacttgcaac
     2941 ttttcgccca caaaaaaggt ggaggttcta catcaaacgg acgtgattca caagcaaaac
     3001 gtcttggagc taaagcagct gacggacaaa ctgtaacagg tggatcaatc ctttaccgtc
     3061 aacgtggtac acacatctat ccaggtgtaa acgttggtcg tggtggagac gatactttgt
     3121 tcgctaaagt tgaaggcgta gtacgctttg aacgtaaagg acgcgataaa aaacaagttt
     3181 ctgtttaccc aatcgcaaaa taaaaaggtt cattgaacct tttatcccga accttgaaat
     3241 gtaaaggtga ggaagctaga aacagcttaa aataaggctt tccgagtttt cggagagcct
     3301 gtttttttat tttgataccc atacttttta atatgtatag tggattgata ctcttcgaaa
     3361 atcaaattca aaccacgtca atttcacctt gccgtactca agtacagcct gcggctaact
     3421 tcctagtttg cactttaatt ttcattgagt atgaatctgg aatagaacac tgttaaaaat
     3481 tgatatgagt ttcctactcg atttcttcag attttatttc aattgactat aagaactgct
     3541 atctggtttc aaatattggc ttgtcgtccc ttcacttgtc tgaatggttt gagccgttcc
     3601 ttctgataag ggaaaagata ttctttagct gaaacggtct gagaatccaa gctaacagat
     3661 ggagagaaaa atagcccagt ctgaagcaca ctagatggga gttgttggaa agcagtcatc
     3721 tagtttttct ttgctgtttt ggcttttttc tttgtcatca gggaaagtga cttgcttcaa
     3781 atcagggagt ttaggaaatt cttcaaacat cttgcccaag ttgtctcatt ttgtaaattt
     3841 tacagccata ggtgtacctc gattctaaat tctacctttt tggcaccaat tagtaattta
     3901 aagttctcag gagttagttg cattgctttt tcatacataa catagtatga cactttatgg
     3961 ttaccgaaca agtctaatca ctccttgcaa aattttgaag atgtcctaca agtttttgag
     4021 aagaatattg caaagttcat agttaagcaa cgatagaata aagtgctttt tgaaaacagg
     4081 tacacttcat gtgaaaaaaa caacatttca gattttctgt tccagaaata gctatcgcta
     4141 tgatataatt attttatgat tattactatt cctataaaaa accaaaaaga tattggcaca
     4201 ccatctgatt cagtcgttgt tctcggctat tttgatggca tacataaggg gcatcaagaa
     4261 ttatttcgtg ttgccaacaa ggctgcgaga aaggatttat tgcctatcgt cgttatgacc
     4321 tttaatgaat ctccaaagat cgctttagag ccttatcatc cagatttgtt tttgcatatt
     4381 ttgaaccctg ctgaacgtga aagaaaatta aagcgcgaag gtgtagaaga attatatctc
     4441 cttgatttta gtagtcaatt cgctagtctc actgcacaag aattctttgc aacttatatc
     4501 aaggctatga atgccaaaat tattgttgca ggttttgatt atacatttgg ttctgacaaa
     4561 aaaacagcag aagatttaaa ggattacttt gatggagaag ttatcattgt tccacctgta
     4621 gaagatgaga aaggaaagat tagttcaact cgtatccgtc aagctatttt agatggaaat
     4681 gtgaaagaag caggaaaact tttgggggca ccgcttccat caagaggtat ggtggttcat
     4741 ggtaatgctc gtggtcgtac aattggttat ccgacagcga atttagtgct tttagaccgt
     4801 acttatatgc cagcagatgg cgtttatgtc gttgatgttg agattcaaag acagaagtat
     4861 cgtgctatgg ctagtgtcgg gaaaaatgtg acctttgatg gagaagaagc acgttttgaa
     4921 gtcaatattt ttgattttaa tcaagatatt tatggggaaa ccgtcatggt ttattggctt
     4981 gatcgcattc gtgatatgac caaatttgac tcagttgacc aattagtgga tcagttaaag
     5041 gctgatgaag aagtaactcg gaattggtct taagagcttg agtaaataaa acaaaaaaga
     5101 ggttgtctgt aacccaaaag atagatgatt tagtctaact tttgaggtca cgacattacc
     5161 tctttttatt ctttttcaaa ggtgaagcct tctcctagga tttcatgggc ttctgtaata
     5221 gttataaagg cttgaggatc gattcgatga atcatttcct tcgttttcac aatttcattt
     5281 cttccgacaa tacagtagat gattttcaaa ttttctttac tatagtagcc ttgaccagaa
     5341 ataaaagtaa cacctcttcc gaggtcatca ttaatcgcct tagcaagttg gtcaggacgt
     5401 tttgtgataa tcataaagcc tttgccggca tatcctcctt caccaatcaa atcaataaca
     5461 cgagaaacaa taaaatcaaa caaaagcgtg taggaaacca atctcaaatc cttgaagatt
     5521 aggagaatca acatgagaat acaaaaatct aagataaaga gcagttttcc tatggatata
     5581 tgagtgtatt tgttgagaat acgagctaga atatcagttc cgccagttgt acctccagca
     5641 ttaaaaataa ttccaaggcc aattcccaat aggattcccg ctataagggc tgtgattagt
     5701 aaatcacctt gaagatcaat atgaagggga atatgctcaa aaaaagctaa ccaggcggac
     5761 aaagctaagg ttcctagtaa actagaatag agggatttgg ctccaaagat cttccaagct
     5821 aggatgaaaa ggggaatatt aatcagcagg ttcatgaggg aaacagggat tttaaaaaga
     5881 taaaaggtga tgagggtaat gcctgtcgcc cctccttcaa agagatgatg gggaactaca
     5941 aaataagtca gtccaaaagc ataaatagca gcacctagta aaatggtaaa aatggggtaa
     6001 atttttttaa tcataggaca cctcttttct tataagttga ttatatcaaa ttttacggaa
     6061 aatttgattg actccattag gatttttaat ctttttttga tataattaga agtaaggaaa
     6121 ccaatctgaa tcctaaaata gaaagattga tactatgaca aaaattaaga ttgtaaccga
     6181 ttcatctgtt actattgaac ctgaactagt aaagcaatta gatattacaa ttgttccatt
     6241 atctgtaatg attgataatg ttgtttattc tgatgcggat ttgaaagaag aaggtaaatt
     6301 tcttcagttg atgcaagaaa gtaagaatct tccgaaaaca agtcagccac ctgtaggtgt
     6361 ctttgctgag atttttgaag acctatgcaa agatggtggc cagattcttg ctattcatat
     6421 gtcccatgct ctttcgggta cggtagaagc agcacgccaa ggtgctagcc tatctactgc
     6481 agatgtgact gttgttgata gttccttcac tgaccaagcc ctgaaattcc aagttgttga
     6541 ggctgcgaag ttagctcaag aaggtaaaga tatggaggca attttatctc atgtagaaga
     6601 ggttaaaaac catacagagc tttatattgg tgtttcaact ttggaaaatc ttgtcaaagg
     6661 tggacgaatt agccgtgtaa ctggcttgtt gagctctctt ctcaatatcc gtgttgtcat
     6721 gcaaatgaaa gaccatgaat tgcagccaat ggttaaaggt cgtggaacta aaacatttaa
     6781 aaaatggtta gatgagttga taacatcgct ttctgaacgt gctgtagcag agattggaat
     6841 ttcatattct ggtagtgatg attgggcaaa agagatgaaa gaaagcttac aagcttatgt
     6901 tgaaaagcca atttctgttt tggaaacggg ttccattatt caaactcaca cgggtgagaa
     6961 cgcttgggct attttgatac gttaccactc ctaaaaaaat aaataaaatg ggaagaaata
     7021 gcgtttttaa cttgacctaa aagggatttt aggatatgat tatatttgtt aattagaaat
     7081 tatttggagg aatcattaac atggcaaaca aacaagattt gatcgctaaa gtagcagaag
     7141 ctacagaatt gactaagaaa gactcagcag cagcagttga agctgtattt gcagcagtag
     7201 ctgactatct tgcagctggt gaaaaagttc agttgatcgg ttttggtaac tttgaagttc
     7261 gtgagcgcgc agaacgtaaa ggtcgcaacc cacaaactgg taaagaaatg acaattgcag
     7321 cttctaaagt accagcattc aaagctggta aagctcttaa agacgctgtt aaataatcag
     7381 tctttaaaaa gcctattgta tcaagctttc tagcttggtc agtaggcttt ttaattatga
     7441 aatctagtaa taaatagagt taaaaagttg aatgttccga aaatatt
//
LOCUS       DBEJHE010000052         7085 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC4 isolate 671759
            SAMN38261586-rid24793303.denovo.52, whole genome shotgun sequence.
ACCESSION   DBEJHE010000052 DBEJHE010000000
VERSION     DBEJHE010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261586
            Sequence Read Archive: SRR26833752
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 7085)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7085)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576136.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576136.1
            Genome Coverage       :: 109x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 19:48:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,067
            CDSs (total)                      :: 2,029
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 131
            CDSs (without protein)            :: 131
            Pseudo Genes (ambiguous residues) :: 0 of 131
            Pseudo Genes (frameshifted)       :: 64 of 131
            Pseudo Genes (incomplete)         :: 59 of 131
            Pseudo Genes (internal stop)      :: 46 of 131
            Pseudo Genes (multiple problems)  :: 32 of 131
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7085
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261586-rid24793303.denovo.52"
                     /strain="GPSC4"
                     /isolate="671759"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            227..472
                     /locus_tag="ACL3EZ_001933"
     CDS             227..472
                     /locus_tag="ACL3EZ_001933"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HGR0393452.1"
                     /translation="MAESIQGWLAQFLVNLFKSITFDCGKEFSKWKDISNHHDSESFF
                     ANLGCPRQRCLNEHSNRLLRCHDLPKQTDFNEVSQEF"
     gene            complement(750..1520)
                     /locus_tag="ACL3EZ_001934"
     CDS             complement(750..1520)
                     /locus_tag="ACL3EZ_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HGR0393453.1"
                     /translation="MVEIIYFLIIIIASGLGSISGMGGGIIIKPLMDSFGYHSVSDIA
                     FYSSFSVFIMAIISTIKRFSQSKEIKWRLIFTVSFSSVLGGFLGYLIFQVLLSQLSVR
                     LVSIVQMILLFVMLLVSFVLTDFKKTYQFDKIGFYMICGLLLGLISSFLGIGGGPLNV
                     SLLMVFFSISIKEATMYSLAIIFFSQLSHLATIVVVTGLNQYHLAPVPVIFLASICGG
                     VLGTVVSKVLPENWVRYCFKGMLFFVMGMTLYNLFHIL"
     gene            complement(1535..2161)
                     /locus_tag="ACL3EZ_001935"
                     /pseudo
     CDS             complement(1535..2161)
                     /locus_tag="ACL3EZ_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782422.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SUMF1/EgtB/PvdO family nonheme iron enzyme"
     gene            complement(2151..2669)
                     /locus_tag="ACL3EZ_001936"
                     /pseudo
     CDS             complement(2151..2669)
                     /locus_tag="ACL3EZ_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095003.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
     gene            complement(2679..2996)
                     /locus_tag="ACL3EZ_001937"
     CDS             complement(2679..2996)
                     /locus_tag="ACL3EZ_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HGR0393454.1"
                     /translation="MDESNLESVMGLIMYGGEAKSNAMEAIQAAKKEDFSKANRRLAD
                     ANAALLQAHKAQTEMLTREAQGEKTSISLLMVHAQDHLMTSLTFVDLAKEVVEVYERF
                     EKN"
     gene            complement(3013..3330)
                     /locus_tag="ACL3EZ_001938"
     CDS             complement(3013..3330)
                     /locus_tag="ACL3EZ_001938"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001151647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGR0393455.1"
                     /translation="MAKVTIMLACAAGMSTSLLVTKMQKAAEDKGLDAEIFAVPAPEA
                     EEIVATKEVNVLLLGPQVRYLLGDFQEKLKDRQIPVAVIPMTDYGMMNGSKVLDLAES
                     LLD"
     gene            complement(3345..4241)
                     /locus_tag="ACL3EZ_001939"
     CDS             complement(3345..4241)
                     /locus_tag="ACL3EZ_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HGR0393456.1"
                     /translation="MKRLISANPSEILQMNAEELKQSILASEGRVVLSENVVTRETFV
                     GDITNSEIARAFGADMILLNCVDVFEPKIYALDSSGDDVIHRLHQLVACPIGVNLEPI
                     DPSAKMLEETQEIVAGRVASVETLNRIEELGFDFVCLTGNPGTGVSNQEIIKAVQSAK
                     ENFSGLIIAGKMHGAGVNEPVAELSVAEQLLEAGADVILVPAVGTVPAFHDQELREVV
                     DLVHSKGGLVLSAIGTSQETSDTDTIKEIALRNKICGVDIQHIGDAGYGGLATVDNIY
                     ALSKAIRGVRHTVSRLARSVNR"
     gene            complement(4244..5506)
                     /locus_tag="ACL3EZ_001940"
     CDS             complement(4244..5506)
                     /locus_tag="ACL3EZ_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HGR0393457.1"
                     /translation="MEKLLQEKLLPVAARLGNNKALVSIRDGITLTIPLLLIGSLLMV
                     IASFPIPGWEKYLGDIGVADYLWKGVDSSFGLLGLVASFGIAYFMARQYKVDGIPAGI
                     VSLSSFITVTPFIRGEAGAGMPTAFMASKGLFVAMILGLINGYIYQWFINHNIQIKMP
                     DGVPPAVSKSFSAIIPGAVTIVGWLIVYATLDKLSLPNLHEIAQVALGGPLGLLGNNV
                     IGLLILIFLNSSFWFVGLHGGNVVNAVMKPLWLANLDANKVAYQTGETLPNIFTSVFM
                     DNFVFIGGGGATIGLVLALGYLAHKKKASKQLKTLAPITVIPGLFNINEPAMFGVPIV
                     LNILLLVPFILAPMFNLLVAWGAMASGLVPLTYTDPGWTMPPVISGLLATGSISGSLL
                     QIVLIVLDVLLYLPFVIAIEKRFKLLED"
     gene            5786..6964
                     /locus_tag="ACL3EZ_001941"
     CDS             5786..6964
                     /locus_tag="ACL3EZ_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HGR0393458.1"
                     /translation="MTLSKKQLQLRAKILETVYTLGPISRIEIATKTGITPATTSSIT
                     NDLIKENILLELGEDEHDTSVGRKKILLDIQAKRFYYIGCELSEKHFTFALGDNLGNI
                     LKEEKEIVTKQLIQEKGNQLINQTLKQFLNNCSDYEIEAIGIALPGRYLDNYKITTNN
                     PLWQHIDLEMIQSHFDKPLFFSNNVNCMAIGKRLFSRQQNDPNFAYFHFARGMHCSYI
                     YDGNIYGKGNLMIGEIGHTVVSSEGEECSCGRKGCLQTFAGESWLIKKSKILYHQSPY
                     SLLPSLVKNADDIDIQVILTAYQLGDTGIITLIHQALLYLSQTILNISMMIDSQKIYL
                     HSPLLTNQHIIQKLYSEMNYKPKLLYNRLPEVIIEPYNDFTAAHSAIALCLYHTILHS
                     "
BASE COUNT         2467 a         1476 c         1007 g         2135 t
ORIGIN      
        1 gttttagaag tagaggtgta ctattctagt ttcaatctac tatattttcg tacaggtgct
       61 tcaatagttt ctatagtaaa atgaaccaaa aatagtacac gttgcggtat aatgttcttg
      121 tggcatattc attagatttt cgtaaaaagt tctctcctat ttgtgagcga acaggtatag
      181 tcaattgatt gtcagtttga agaccaagag tcgtaaggca aaggatatgg cagaatccat
      241 ccaagggtgg ctggcacaat ttctagtgaa cctctttaaa tctattacgt ttgactgtgg
      301 aaaagagttt tcaaaatgga aagatatttc caatcatcac gatagtgaga gcttttttgc
      361 gaatctagga tgtccaagac agcggtgtct caacgaacat tcaaatagac ttttaaggtg
      421 tcatgacttg ccaaagcaga cagatttcaa cgaagtcagt caagaatttt aggctgggta
      481 aaaactcaat ttcaggagaa aatgaaataa atattcccac aataaaacgc atagtatcaa
      541 agtttttcca acacctgata ttatacattt tttaatttta aagacttttt cccagcctca
      601 agaaatcaca tcccacctaa atcctttgga taccaaatac ctcatcaggt attttctgag
      661 ttggtaagac tgtctagctt aatttgacaa atggagggcg ttaaatccag tttttacagg
      721 aagtctattt aaatattttc acactgacct tacaaaatat gaaataaatt atataaagtc
      781 attcccatga caaagaataa catcccttta aaacagtatc ttacccaatt ttcaggtaag
      841 acttttgata caaccgtccc caatacccct ccgcatatag aagcaagaaa aataactgga
      901 acaggtgcta aatgatactg atttaaacct gtaaccacaa caattgtagc caaatgagac
      961 agctgggaaa agaaaataat tgcaagagaa tacatcgttg cttcttttat cgaaatagaa
     1021 aaaaacacca tcaataaaga tacattgagc ggaccaccac caatccctaa aaaactagaa
     1081 atcaagccca atagaagacc acaaatcata tagaatccta tcttatcaaa ttgataagtt
     1141 tttttaaaat ctgttaaaac aaatgataca agtaacatca caaatagtaa aatcatttga
     1201 acaatagata ctagccgtac tgataattga gataacaaaa cttgaaaaat aagataacct
     1261 agaaatcctc ctaaaacaga agaaaaggat accgtaaaaa tcaatctcca ttttatctct
     1321 ttactttgtg aaaatctttt gattgttgaa ataatcgcca ttataaaaac agagaaacta
     1381 gaataaaaag caatatcact gaccgaatgg tatccaaaac tatccataag tggcttaatt
     1441 ataattccac cacccatgcc tgatatagaa cccaatccac tagctattat aatgattaga
     1501 aaataaataa tctcaaccac tttttaagtc catcctattc tttcaaacat ctaaaaccta
     1561 gatggctact agtggaagta gaaatacatc catttctagc agctactcgg tatcgattac
     1621 aataagaaca atgacataaa aaggaacctc ctctgatagc atactcctca tcttgtatcc
     1681 catattttgg taactcatag tcatcttcat taaaactagc taataaggta tatctcggat
     1741 tgcgacacca ttcccaaaca ttcccaatca tttgatatag accaaaatca ttaggtaaaa
     1801 attcatagac aggagccgtt cctataaatc catctaaggc agtattttca taaggaaatc
     1861 ttccttgcca agtattggca tgataatatc caccttctaa aagagtatct ccccaaagat
     1921 attcagattg tcttcctcct ctagcagcat attcccactg tgcttcagtc ggtaaagaca
     1981 ttccgctcca attacagaaa gccaatgcat cttctaaagc aacatgaact actggatggt
     2041 cttctaaacc cactagatta ctgttctcac cgtagggatg tttccagcaa gcgttcggaa
     2101 cttgtaacca ccacggagcc ccagcaggat gaggatatcc ctccctttct gcctctggca
     2161 ttaatatggt ttcctggaat cacattccca atagttacca tcagattttt accatcaaat
     2221 gctagattat caattccttg taagatctga tctaatttca catctcctac atttgccaaa
     2281 gggaaactct ttgtaactgt acttccaatc gaaatgacaa acgaagcaag tgataccaaa
     2341 ccagtagaaa ctgtatcaac cttgtaaatc ttagcgatat tcactcccaa gcaatagatg
     2401 aacaacaagg aaacaattgg tatacttccc ttgaatacca aattattgat gtcaacaagc
     2461 cactgaaagg ttttcgtaat actttctagg tgaaattgtt gtggtaaatc cactagaaaa
     2521 gcatttaata acaaagcaat ggaacctgtc ataataacag gcatagtccc cacaaatgaa
     2581 tcacgtaaag caactaaaaa cttctgattc ccaactttca ttgcaattgg agaaagtttt
     2641 tcttgcattt tatccaacat tgtattcata ccaaactcct aatttttttc aaatcgttcg
     2701 tatacttcta ccacttcttt cgccaagtca acaaaagtca gactcgtcat taaatgatct
     2761 tgcgcgtgta ccatcaagag gctaattgat gttttttccc cctgtgcctc tcttgtcaac
     2821 atttctgttt gagccttatg cgcctgtaat aaggcagcat tcgcatcagc taatcttcga
     2881 ttggctttag agaaatcctc tttttttgct gcctgaatag cctccatagc attacttttg
     2941 gcttccccac catacataat tagccccatt acagattcta aattactttc atccataaca
     3001 ttctcctcaa tcttagtcta ataaactttc agctaaatct aaaactttag aaccattcat
     3061 cattccgtaa tctgtcatcg gaataaccgc cacaggaatc tgtctatctt ttagtttttc
     3121 ttgaaagtcc cctagtaaat agcgaacttg aggacctaaa agcaacacat ttacttcttt
     3181 tgttgctaca atttcttctg cttcaggagc tggaactgca aaaatttctg catccaaccc
     3241 cttatcttct gctgcctttt gcatctttgt cactagcaga cttgtactca tacctgctgc
     3301 acatgctaac ataattgtta ctttagccat agcttactcc tttatcacct atttactgac
     3361 ctagccaagc gagatactgt atgtctcact cctctaattg ccttgctcaa tgcataaata
     3421 ttatcgactg ttgccagtcc cccatatcct gcgtcaccta tatgttgaat atcaactcca
     3481 caaattttat ttctaagtgc aatttccttg atagtatctg tatcagatgt ttcttggcta
     3541 gtaccaatag cactcaatac aagaccaccc ttactatgaa cgagatcaac gacttcacgc
     3601 aactcttggt catgaaaggc tggaacggtt ccaactgctg gaacaagtat cacatccgca
     3661 cctgcttcca acaattgctc tgcgacagaa agctctgcca caggctcatt cactcctgcc
     3721 ccgtgcattt taccagctat aatcaaacct gagaaattct ctttagcaga ttgaactgct
     3781 ttgataatct cttgattgct aactcctgtt ccaggatttc cagtcaaaca gacaaagtca
     3841 aaacctaact cctctattcg attcaatgtt tcaacactag caacacgacc tgcaacaatt
     3901 tcctgtgttt cctctagcat ctttgcagat gggtcaatcg gttccaaatt tacaccaatt
     3961 ggacaagcaa caagctggtg taagcgatga ataacatcat cacctgaact atccaaagca
     4021 taaattttag gctcaaaaac atcaacacaa ttcaataaaa tcatatcagc tccaaaagct
     4081 ctagcaattt cagaattagt tatatcccca acaaatgtct cacgagtaac tacattttca
     4141 gatagaacaa ctctaccttc acttgctaaa atactttgtt ttaattcttc agcattcatc
     4201 tgtaatatct cagatggatt tgcactaatt aaacgtttca ttctcaatcc tccaataact
     4261 taaaccgttt ttcaatagct attacaaatg gtaaataaag taagacatcc aaaacaatca
     4321 atacaatttg taataatgaa ccagaaatac ttcctgtagc aagtaaacca cttataacag
     4381 gtggcatagt ccaacctgga tctgtataag ttagcggaac caaacctgat gccattgctc
     4441 cccacgctac tagtaagtta aacattggag ctaagataaa tggaactagt aacaaaatgt
     4501 tcaaaacaat aggaacgcca aacattgctg gttcatttat attaaataat ccaggtataa
     4561 cagttatagg tgccaaagtt tttagttgtt tactagcttt cttcttatgt gctaaatatc
     4621 ctaacgcaag aactaaacct atggttgcac caccgccacc tatgaataca aaattatcca
     4681 taaatacgct agtaaaaata tttggaagag tttctccagt ttgataagct actttatttg
     4741 catctagatt agctaaccat aacggtttca taactgcatt aacaacattt cctccgtgta
     4801 atcctacaaa ccaaaaacta ctattaagga aaattaagat aagaagacca ataacattat
     4861 ttcctaaaag tccaagtgga cctcccaaag ctacttgagc aatttcatga agattaggta
     4921 aacttaattt atctaaagtt gcataaacaa tcaaccaacc aacaatagtc actgcaccag
     4981 gaataatggc actaaagctt ttagatactg ctggtggaac accatccggc atttttatct
     5041 gtatattatg atttataaac cattggtaga tatagccatt aatcaatcct aaaatcatag
     5101 caacaaataa accttttgat gccatgaaag cggtaggcat tcctgctcca gcctctcctc
     5161 taatgaaagg cgtaactgta ataaaagatg ataatgacac aataccagca ggaataccat
     5221 caactttgta ttgtctagcc ataaagtaag cgataccaaa actagctaca agaccaagta
     5281 atccaaaact actatcaaca cccttccata aatagtcagc aacaccaata tcacccagat
     5341 atttttccca tcctggaata ggaaaacttg caataaccat tagtaatgaa cctatcaaca
     5401 ataaaggtat agttagagta ataccgtctc gaatagaaac caacgcttta ttattaccca
     5461 atctagccgc tactggaagt aacttttctt gtaataattt ttccataacc ttttcctctt
     5521 aaatatattt tattatcaaa agttatcaat tatctttatt ttttgacgtc aagttgttat
     5581 ttgattatct tttgttattt atattttaca actataagaa agccttgtca aggatttgtg
     5641 taaacatttg attatttttt attatcaata tataataaaa agagaccagt aagtaatgaa
     5701 aagcttaaaa aaattaacat ctacatttat ccatagcaaa aaatcatagg attttaagaa
     5761 tctgacaact aggaagaaaa ctaatatgac cttatctaag aaacaattac aactaagagc
     5821 taaaatactg gaaacagttt acacattagg tcccatttca cgaattgaaa tcgctactaa
     5881 aacaggaata acacctgcaa caactagcag tatcacaaat gatctgatta aagaaaatat
     5941 tctcttagaa cttggtgaag acgaacacga tacaagcgta gggagaaaaa aaatcctgct
     6001 agacattcaa gctaaacgat tttactacat tggttgtgaa ctatctgaaa aacatttcac
     6061 ttttgcttta ggagataatc taggaaatat cttaaaggaa gagaaagaaa ttgttactaa
     6121 acagttaatc caagaaaagg gaaatcaact cattaaccag acactaaagc aattcttaaa
     6181 taactgctct gattatgaaa tagaagcaat tggaatcgcg ctacctggtc gctatttaga
     6241 taattataaa ataacaacaa acaatccttt atggcaacat atcgacttag aaatgattca
     6301 atcccacttt gataagcctt tgtttttctc taacaatgtt aactgtatgg ctataggtaa
     6361 acgcctattt agtcgccaac agaatgaccc taattttgct tattttcatt ttgctagagg
     6421 tatgcactgt tcttatatct acgacggaaa catttatggg aaaggaaatc taatgattgg
     6481 agaaataggg catacagttg tttcatctga gggagaagaa tgtagctgcg ggcgcaaggg
     6541 atgcttacaa acttttgctg gagaatcttg gttaatcaaa aaatcaaaaa ttctatatca
     6601 tcaatctccc tattctctac ttcctagttt agtcaaaaat gccgatgata ttgatatcca
     6661 agttatttta accgcttatc aattaggtga cactggaata atcacactta tccatcaagc
     6721 cttactctat cttagtcaaa ccattttaaa tatcagtatg atgattgact ctcaaaaaat
     6781 ctacctacat agtcctttac taacaaatca acacatcatc caaaaactat atagtgaaat
     6841 gaactacaaa cccaaactgc tctataatcg cctacctgaa gtcattattg aaccttacaa
     6901 tgattttaca gccgcacact cagctattgc actctgtttg tatcatacaa ttctacattc
     6961 ttaattttct attacattta ataaataggc taaaaagagg gagtatatca taaaaagcga
     7021 ataaacctgt tttctgaaaa tcagaattct gttttgttcg ctttctttat atttggaatt
     7081 atact
//
LOCUS       DBEJHE010000053         6809 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC4 isolate 671759
            SAMN38261586-rid24793303.denovo.53, whole genome shotgun sequence.
ACCESSION   DBEJHE010000053 DBEJHE010000000
VERSION     DBEJHE010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261586
            Sequence Read Archive: SRR26833752
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 6809)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6809)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576136.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576136.1
            Genome Coverage       :: 109x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 19:48:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,067
            CDSs (total)                      :: 2,029
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 131
            CDSs (without protein)            :: 131
            Pseudo Genes (ambiguous residues) :: 0 of 131
            Pseudo Genes (frameshifted)       :: 64 of 131
            Pseudo Genes (incomplete)         :: 59 of 131
            Pseudo Genes (internal stop)      :: 46 of 131
            Pseudo Genes (multiple problems)  :: 32 of 131
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6809
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261586-rid24793303.denovo.53"
                     /strain="GPSC4"
                     /isolate="671759"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            79..1054
                     /locus_tag="ACL3EZ_001942"
                     /pseudo
     CDS             79..1054
                     /locus_tag="ACL3EZ_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862469.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
     gene            1231..2238
                     /gene="gap"
                     /locus_tag="ACL3EZ_001943"
     CDS             1231..2238
                     /gene="gap"
                     /locus_tag="ACL3EZ_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HGR0393459.1"
                     /translation="MVVKVGINGFGRIGRLAFRRIQNVEGVEVTRINDLTDPVMLAHL
                     LKYDTTQGRFDGTVEVKEGGFEVNGKFVKVSAERDPEQIDWATDGVEIVLEATGFFAK
                     KEAAEKHLKGGAKKVVITAPGGNDVKTVVFNTNHDVLDGTETVISGASCTTNCLAPMA
                     KALQDNFGVVEGLMTTIHAYTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAIG
                     LVIPELNGKLDGSAQRVPTPTGSVTELVAVLEKNVTVDEVNAAMKAASNESYGYTEDP
                     IVSSDIVGMSYGSLFDATQTKVLDVDGKQLVKVVSWYDNEMSYTAQLVRTLEYFAKIA
                     K"
     gene            complement(2305..3180)
                     /locus_tag="ACL3EZ_001944"
     CDS             complement(2305..3180)
                     /locus_tag="ACL3EZ_001944"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HGR0393460.1"
                     /translation="MQFTFTLPASIPQMTVKQLLEEQLLIPRKIRHFLRIKKHILINQ
                     EEVHWNEIVNPGDVCQLTFDEEDYPQKTIPWGNPDLVQEVYQDQHLIIVNKPEGMKTH
                     GNQPNEIALLNHVSTYVGQTCYVVHRLDMETSGLVLFAKNPFILPILNRLLEKKEISR
                     EYWALVDGNINRKELVFRDKIGRDRHDRRKRIVDAKNGQYAETYVSRLKQFSNKTSLA
                     RCKLKTGRTHQIRVHLSHHNLPILGDPLYNSKSKTSRLMLHAFRLSFTHPLTLEKLTF
                     TTLSNTFEKELKKNG"
     gene            3267..5462
                     /gene="pbp2a"
                     /locus_tag="ACL3EZ_001945"
     CDS             3267..5462
                     /gene="pbp2a"
                     /locus_tag="ACL3EZ_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein PBP2A"
                     /protein_id="HGR0393461.1"
                     /translation="MKLDKLFEKFLSLFKKETSELEDSDSTILRRSRSDRKKLAQVGP
                     IRKFWRRYHLTKIILILGLSAGLLVGIYLFAVAKSTNVNDLQNALKTRTLIFDREEKE
                     AGALSGQKGTYVELTDISKNLQNAVIATEDRSFYKNDGINYGRFFLAIVTAGRSGGGS
                     TITQQLAKNAYLSQDQTVERKAKEFFLALELSKKYSKEQILTMYLNNAYFGNGVWGVE
                     DASKKYFGVSASEVSLDQAATLAGMLKGPELYNPLNSVEDSTNRRDTVLQNMVAAGYI
                     DKNQETEAAEVDMTSQLHDKYEGKISDYRYPSYFDAVVNEAVSKYNLTEEEIVNNGYR
                     IYTELDQNYQANMQIVYENTSLFPRAEDGTFAQSGSVALEPKTGGVRGVVGQVADNDK
                     TGFRNFNYATQSKRSPGSTIKPLVVYTPAVEAGWALNKQLDNHTMQYDSYKVDNYAGI
                     KTSREVPMYQSLAESLNLPAVATVNDLGVDKAFEAGEKFGLNMEKVDRVLGVALGSGV
                     ETNPLQMAQAYAAFANEGLMPEAHFISRIENASGQVIASHKNSQKRVIDKSVADKMTS
                     MMLGTFTNGTGISSSPADYVMAGKTGTTEAVFNPEYTSDQWVIGYTPDVVISHWLGFP
                     TTDENHYLAGSTSNGAAHVFRNIANTILPYTPGSTFTVENAYKQNGIAPANTKRQVQT
                     NDNSQTDDNLSDIRGRAQSLVDEASRAISDAKIKEKAQTIWDSIVNLFR"
     gene            5515..5667
                     /gene="rpmG"
                     /locus_tag="ACL3EZ_001946"
     CDS             5515..5667
                     /gene="rpmG"
                     /locus_tag="ACL3EZ_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HGR0393462.1"
                     /translation="MALKKASLACAVCGSRNYSIKISGNPKPTRLEVNKFCKHCGKYT
                     THRETR"
     gene            5677..5853
                     /gene="secE"
                     /locus_tag="ACL3EZ_001947"
     CDS             5677..5853
                     /gene="secE"
                     /locus_tag="ACL3EZ_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HGR0393463.1"
                     /translation="MRFIGDIFRLLKDTTWPTRKESWRDFRSIMEYTAFFVVIIYIFD
                     QLIVSGLIRFINIF"
     gene            5908..6444
                     /gene="nusG"
                     /locus_tag="ACL3EZ_001948"
     CDS             5908..6444
                     /gene="nusG"
                     /locus_tag="ACL3EZ_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000376740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0032784 - regulation of DNA-templated
                     transcription elongation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HGR0393464.1"
                     /translation="MDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEIP
                     TQTVQVEKNGKRKEVEENRFPGYVLVEMVMTDEAWFVVRNTPNVTGFVGSHGNRSKPT
                     PLLEQEIRDILVSMGQTVQEFDFDVEIGQTVRIIDGAFADYTGKITEIDNNKVKMIIS
                     MFGNDTVAEVNLNQIAEL"
     gene            6566..>6809
                     /locus_tag="ACL3EZ_001949"
     CDS             6566..>6809
                     /locus_tag="ACL3EZ_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HGR0393465.1"
                     /translation="MIKELYEEVQGTVYKCRNEYYLHLWELSDWEQEGMLCLHELISR
                     EEGLVDDIPRLRKYFKTKFRNRILDYIRKQESQKRRY"
BASE COUNT         2135 a         1166 c         1489 g         2019 t
ORIGIN      
        1 tgctcttgtt tcaattgact atagttcacg gatacagttg ggaaagaagc tattaaatat
       61 ttggagagtc cttttgggat gaacatgtca aatattacta tagatgggca agaaaagatg
      121 ggcaagaaat ggatctgagt caaacgatgc ttcttatgct caagtagtga gtctttatga
      181 tgatacaagt atctctgtta gtaataatga gacggacaaa gtgttgactg gatccctcta
      241 tactgaaaca aatgaacagg gattaacgat tccaatcagt ttactaaaaa attggaatga
      301 acagacagga aaaaatttga caactaatga tcttattggc aaatcagtct cagccagcat
      361 tgtagaaagt gctgccgaaa ctagtaagat tgctcaattt caaacgaaga ttgtacgtgt
      421 aatcaatgat gaagatgaca tggaggacag caacagtttc atgctgtctc atcaaatgga
      481 aacgattttg aaagaggctg gatttacgaa agctgtatct tattttatct tggaactcaa
      541 agatccatca cagacaaaag tagtaacaga agaattacag aaaaataaga agtatactgt
      601 gctttctcaa cagagagttc ttgatattgt gattaccttt attcgtgtta ttcagggatt
      661 attgattgtg ctttcatcac aagctattgt ggtagcagcg gttatgattg gtatcattat
      721 ttacatcaat atcatgcaac gttccaagga aataggtgtc atgaaagcag ttggttatca
      781 gaatcgtggt gtcaaaggaa tttttattta cgaggctatc tggattgtag gcatcgcctt
      841 gctgctggca tttttggttg cacaaggggt gggaagtttg gcgaatgcga ttgtaagtca
      901 cttttaccca tccatcacta aggtttttga attaaatctt ttatctgttt taggaactct
      961 agttttcgct ctattacttg gttatgtctc agcctacttc ccggcgcgta agattagtaa
     1021 aatggatcct gtagaatcgt tacgctatga ataataaggg attccttgat ttacagtctt
     1081 aaaaagaaac tcacatagaa aaacaatggc catacttgca attcaactca aatagttgta
     1141 taataggttt gttgaaaggt gatttgtagt gattcaagtt actcttttca caataaaaat
     1201 ttcatgattt tcataaggag gaaatcacta atggtagtta aagttggtat taacggtttc
     1261 ggacgtatcg gtcgtcttgc tttccgtcgt atccaaaacg tagaaggtgt tgaagttaca
     1321 cgcatcaacg accttacaga tccagttatg cttgcacact tgttgaaata cgacacaact
     1381 caaggtcgtt tcgacggtac tgttgaagtt aaagaaggtg gattcgaagt taacggtaaa
     1441 ttcgttaaag tttctgctga acgtgatcca gagcaaatcg actgggctac tgacggtgta
     1501 gaaatcgttc ttgaagctac tggtttcttt gctaagaaag aagcagctga aaaacacctt
     1561 aaaggtggag ctaaaaaagt tgttatcact gctcctggtg gaaacgacgt taaaacagtt
     1621 gtattcaaca ctaaccacga cgttcttgac ggtactgaaa cagttatctc aggtgcttca
     1681 tgtactacaa actgcttggc tccaatggct aaagctcttc aagataactt tggtgttgtt
     1741 gaaggattga tgactactat ccacgcttac actggtgacc aaatgatcct tgacggacca
     1801 caccgtggtg gtgaccttcg ccgtgctcgc gctggtgctg caaacatcgt tcctaactca
     1861 actggtgctg ctaaagctat cggtcttgta atcccagaat tgaacggtaa acttgacgga
     1921 tctgcacaac gcgttccaac tccaactgga tcagttactg aattggtagc agttcttgaa
     1981 aagaacgtta ctgttgatga agtgaacgca gctatgaaag cagcttcaaa cgaatcatac
     2041 ggttacacag aagatccaat cgtatcttca gatatcgtag gtatgtctta cggttcattg
     2101 tttgacgcaa ctcaaactaa agttcttgac gttgacggta aacaattggt taaagttgta
     2161 tcatggtacg acaacgaaat gtcatacact gcacaacttg ttcgtactct tgaatacttc
     2221 gcaaaaattg ctaaataatt cttgagttga tagaaagcaa ggctttgtgg tcttgctttt
     2281 tatatagaaa aatggatgac acgatcatcc attctttttt aattcttttt caaatgtatt
     2341 tgaaagggta gtgaaagtta gcttttctaa agtaagtggg tgggtaaagg aaagtcggaa
     2401 ggcatgaagc ataagccgac ttgtctttga tttactatta tagagagggt cgcccaggat
     2461 aggaagatta tgatgcgaaa ggtgcacacg aatctgatgg gttcgccctg tctttagctt
     2521 gcaacgagcc aaggaagtct tgtttgagaa ttgctttaat ctgcttacat acgtttcagc
     2581 atattgccca ttttttgcat caactattct ttttctacga tcatggcgat cacgtccaat
     2641 tttgtctctg aaaacaagtt cttttctgtt gatatttcca tcaactagag cccaatattc
     2701 tctagaaatc tcttttttct ccaataagcg attgagaatg ggcaggataa aaggattttt
     2761 ggcaaagaga actaagccac tggtttccat gtccagacga tgaacgacat agcaggtttg
     2821 gccaacatag gtactgacat ggttaagaag ggcaatttcg tttggttgat taccatgcgt
     2881 tttcatcccc tctggtttgt ttacaataat caagtgttga tcttgataaa cttcctgcac
     2941 taagtctggg ttgccccaag ggatcgtctt ttggggataa tcttcctcgt caaaagtcaa
     3001 ctggcaaaca tctccaggat ttacgatttc gttccagtgg acttcttctt gatttatcaa
     3061 aatatgtttc ttgattctca aaaaatgacg gatttttcta gggatgagga gttgttcctc
     3121 aagtaattgc tttaccgtca tttgaggtat agaggcgggt aatgtaaatg tgaattgcat
     3181 acagatattg taacaaaaaa agccctattt ggataggaaa tagctaaatt cttgtcttcc
     3241 tatgatgaag atgataaaat aaacgcatga aattagataa attatttgag aaatttcttt
     3301 ctctttttaa aaaagaaaca agtgaactag aggactctga ttctactatc ttacgtcgct
     3361 ctcgtagtga tcgaaaaaaa ttagcccaag taggtccgat tcgaaaattc tggcgtcgtt
     3421 atcatctaac aaagattatc cttatactag gtttgagtgc aggcttgcta gttggaatct
     3481 atttgtttgc tgtagccaag tcgaccaatg tcaatgattt gcaaaatgcc ttgaaaactc
     3541 ggactcttat ttttgaccgt gaagaaaaag aggctggtgc cttgtctggt caaaagggaa
     3601 cctatgttga gctgactgac atcagtaaaa acttgcagaa tgctgttatt gcgacagaag
     3661 accgttcttt ctataaaaat gacgggatta actatggccg tttcttcttg gctattgtca
     3721 ctgctggacg ttcaggtggt ggctctacca ttacccaaca gctggctaaa aacgcctatt
     3781 tatcgcagga tcaaactgtt gagagaaaag cgaaagaatt tttccttgcc ttagaattaa
     3841 gcaaaaaata tagtaaggag caaattctaa ccatgtacct taacaacgct tattttggaa
     3901 atggtgtgtg gggtgtagaa gatgcgagta agaaatactt tggagtttct gcatcagaag
     3961 tgagtctgga tcaagctgcg actctggcag ggatgctcaa ggggccggaa ctgtataatc
     4021 ccttgaattc cgtagaagat tctactaatc ggcgcgatac tgtcttgcag aatatggttg
     4081 cagcaggata tattgataaa aaccaagaaa ccgaagctgc tgaagttgat atgacttcgc
     4141 aattgcacga taagtatgaa ggaaaaatct cagattaccg ttatccctct tattttgatg
     4201 cggtggttaa tgaagctgtt tccaagtata atctaacaga ggaagagatt gtcaataatg
     4261 gctaccgcat ttacacagag ctggaccaaa actaccaagc aaatatgcag attgtttatg
     4321 aaaacacatc gctatttccg agggcagagg atggaacgtt tgctcaatca ggaagtgtag
     4381 ctctcgaacc gaaaacaggg ggagttcgtg gagttgtcgg tcaagttgct gacaatgata
     4441 aaactggatt ccggaatttc aactatgcaa cccaatcaaa gcgtagtcct ggttctacaa
     4501 ttaagccttt agttgtttat acaccagcag ttgaagcagg ctgggctttg aataagcagt
     4561 tggataacca taccatgcag tatgatagct ataaggttga taactatgca gggatcaaaa
     4621 caagtcgaga agttcctatg tatcaatcct tggcagaatc gcttaatcta cctgctgttg
     4681 ccactgttaa tgatttgggt gttgacaagg cttttgaggc aggcgaaaaa ttcggactca
     4741 acatggaaaa ggtcgaccgt gttcttggtg tcgccttggg aagcggtgtt gaaaccaacc
     4801 ctcttcaaat ggctcaagca tacgctgcct ttgcaaatga aggtttaatg cctgaagctc
     4861 attttattag tagaattgaa aatgctagtg gacaagttat tgcgagtcat aaaaattcac
     4921 aaaaacgggt gattgataag tctgtagctg acaagatgac cagtatgatg ttggggactt
     4981 tcaccaacgg taccggtatt agttcatcgc ctgcagacta tgtcatggca gggaaaactg
     5041 gaacaactga agcagttttc aatccggagt acacaagtga ccagtgggta attggttata
     5101 ctccggatgt agtgattagc cactggcttg gctttccgac cactgatgaa aatcactatc
     5161 tagctggctc tacttcaaac ggtgcagctc atgtctttag aaacattgcc aataccattt
     5221 taccttatac gccaggaagt acctttacgg ttgaaaatgc ttataagcaa aatggaattg
     5281 caccagccaa tacaaaaaga caagtacaaa ccaatgataa tagccagaca gatgataatt
     5341 tgtctgatat tcgagggcgt gcgcaaagtc tagtagatga ggctagccgg gctatctcag
     5401 atgcgaagat taaggaaaag gctcaaacaa tatgggattc gatagtcaat ctatttcgct
     5461 aagatgcttg tcaaagccta gctttcttgt tataatggat aagatggagg cgttatggca
     5521 ctaaaaaaag caagcctagc ttgtgcggtt tgtggttcga gaaactattc aatcaagatc
     5581 agcggaaacc ccaagcctac acgactagaa gtaaataaat tttgtaagca ttgtggcaag
     5641 tacactacac acagagaaac gagataggag agagcgatgc gttttattgg agatattttt
     5701 agacttctta aagacacaac atggccaact cgcaaggaaa gctggagaga ttttcgttct
     5761 atcatggaat acacagcttt ctttgtagta attatttaca tttttgacca gttgattgtt
     5821 tcaggtttga ttcgatttat taacattttt tagaagatta gtggagttaa ttacactaga
     5881 aatcttctat ttatgaaagg aaatatcatg gatagttttg ataaaggatg gtttgtttta
     5941 caaacttatt ctggttatga aaataaggtg aaagaaaatc tattacaacg tgcacaaacc
     6001 tacaatatgt tggataatat tctacgcgtt gaaattccaa cacaaacagt gcaagttgaa
     6061 aaaaatggaa agagaaaaga agtagaagaa aatcgctttc caggttatgt tcttgtagaa
     6121 atggtcatga cagatgaagc ttggtttgtt gttcgaaaca caccaaatgt tacaggattt
     6181 gtcggatcac acgggaacag atcaaaacca actccattat tggaacaaga aattcgtgac
     6241 attttggtat ctatgggaca aactgttcaa gaatttgatt tcgatgttga gattggtcaa
     6301 actgtacgta ttattgatgg tgcttttgca gactacactg gtaagattac agaaattgat
     6361 aataacaaag tgaaaatgat tatctctatg tttggtaatg acacagttgc agaagtaaac
     6421 ctaaaccaaa tcgcagaatt ataaccctga gagaggctgg agcctctctt ttttgtgcag
     6481 tttaggagct aaagggaaca gaatggagaa aatggaacaa atgtgttttc taatctgtta
     6541 gactgtatct agaaagggga aaattatgat taaagaattg tatgaagaag tccaagggac
     6601 tgtgtataag tgtagaaatg aatattacct tcatttatgg gaattgtcgg attgggagca
     6661 agaaggcatg ctctgcttac atgaattgat tagtagagaa gaaggactgg tagacgatat
     6721 tccacgttta aggaaatatt tcaagaccaa gtttcgaaat cgaattttag actatatccg
     6781 taaacaggaa agtcagaagc gtagatacg
//
LOCUS       DBEJHE010000054         6568 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC4 isolate 671759
            SAMN38261586-rid24793303.denovo.54, whole genome shotgun sequence.
ACCESSION   DBEJHE010000054 DBEJHE010000000
VERSION     DBEJHE010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261586
            Sequence Read Archive: SRR26833752
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 6568)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6568)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576136.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576136.1
            Genome Coverage       :: 109x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 19:48:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,067
            CDSs (total)                      :: 2,029
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 131
            CDSs (without protein)            :: 131
            Pseudo Genes (ambiguous residues) :: 0 of 131
            Pseudo Genes (frameshifted)       :: 64 of 131
            Pseudo Genes (incomplete)         :: 59 of 131
            Pseudo Genes (internal stop)      :: 46 of 131
            Pseudo Genes (multiple problems)  :: 32 of 131
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6568
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261586-rid24793303.denovo.54"
                     /strain="GPSC4"
                     /isolate="671759"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(45..398)
                     /locus_tag="ACL3EZ_001950"
     CDS             complement(45..398)
                     /locus_tag="ACL3EZ_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HGR0393466.1"
                     /translation="MELVLPNNYVVIDEEVMMYLDGGDYLSKRACQGICAALAMSPGT
                     FIALAGAAVLTKKLINYIKVGGLGGWLIGAAAGVLATAAGKIAYCIGYGVLNRGCDIN
                     GNPYPWDGFISATVR"
     gene            complement(454..1356)
                     /locus_tag="ACL3EZ_001951"
     CDS             complement(454..1356)
                     /locus_tag="ACL3EZ_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0393467.1"
                     /translation="MIRKLIVFLLMLPLFVLWLELHVLVNNLLLNLESPLDFVISMSL
                     AFCSLILSKIVLDILYALKDLYKKEGLIKIFPFIFIRRKKVNVRFSPYFSFHRKSLSP
                     DDLRSRIIWSFILEIAIILVFILKIPFAIIMLTTIFFWTIMDINHLVFNKTEFLFNQN
                     KWEKEDSFESDLTKTLKDKIQKSELSYSDLMSLQLYDAMNQSTFLTDSELFEDILKKI
                     EDSHNTLLCTGLVELLMYEMSISNNNNWQEKVDKIRIHLIRINQLDFFYYTSWLRQNF
                     DFCMNREYHKMKSRKLLLSNKKIV"
     gene            complement(1375..1557)
                     /locus_tag="ACL3EZ_001952"
     CDS             complement(1375..1557)
                     /locus_tag="ACL3EZ_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000511668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0393468.1"
                     /translation="MGIKMEKIFVIIFFVCLFISSITFLAYDFVSEEIKKLIIWMNVV
                     FLILIIAMMIYPKLRK"
     gene            complement(1564..1938)
                     /locus_tag="ACL3EZ_001953"
     CDS             complement(1564..1938)
                     /locus_tag="ACL3EZ_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPH_0224 family bacteriocin-like peptide"
                     /protein_id="HGR0393469.1"
                     /translation="MELVLPNNYVVLEQEEMMYLDGGFSIPRWPVATAINIAFNGVLG
                     GGAISLVRNYIRNYGLRRVTSAIAGAAARYVGVRVANRVAGFALSAINGFAAWMSIGD
                     AITTIWANNDVNRRDPNLNALW"
     gene            complement(2151..2333)
                     /locus_tag="ACL3EZ_001954"
     CDS             complement(2151..2333)
                     /locus_tag="ACL3EZ_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000487114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0393470.1"
                     /translation="MFQLGDKTRITFAIIGASCILVSMYLIPLINTDNKFWEILLFII
                     GVLLIGIALLSQKNKF"
     gene            complement(2314..3291)
                     /locus_tag="ACL3EZ_001955"
     CDS             complement(2314..3291)
                     /locus_tag="ACL3EZ_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0393471.1"
                     /translation="MKNKRYFFDTILIILLLISTIFCVSPVFIKLDILGTPSHAILTF
                     VLAIPLFYILSQCLHTLLLLVSSIFCKLRPIYFYFIFVIIIGARKYYRILFHQLMGFS
                     PGIAVFYKESQTTKNLFKFYYFLYFTTLISYYFFFTFVYDKPLLLPLISFSIIIALVQ
                     KLYRIENQQLFLLKSKVLTILESKKNCEFNLQDYHEIWKLQSKSELPCVALSYISLIK
                     PYLSESVREQIDLLEVKRFKKINHPISLYGMLDVIKLNLYLRHYNEKNKYESMLNKIL
                     EVRPDFVLIEQNIDDSLNSSQPLSLSLAISEIQLLLEVYIGIKHVSIRR"
     gene            complement(3605..4663)
                     /locus_tag="ACL3EZ_001956"
     CDS             complement(3605..4663)
                     /locus_tag="ACL3EZ_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0393472.1"
                     /translation="MKDDQKYLLAGLYSLLVAIFYFPLIESKGIFVSILMAVLLLYLI
                     YFIATVIHIVIIKFIRKKSFKYLVLYPFTYDGSWRFQPINLLYFPEMVRDVIPINLVQ
                     EYCQGQPYGLLKKMLKRIRLSREISLLLATIIVYFFTHRILPLSVFTFIFSYILLFAQ
                     SYLGGNTAWIGNRRLIIDDEFEKILLSKSYIKEISSARYSEYLTCEYKNFTPIILLAI
                     FENLLDSYLLQNQSEVDLDIFYKVLPLLYKEKYTMGFNYFVSLNYLLYKVGFLGIIYD
                     NEALRDLSKQYLNKNISELQDGSFEGGIQDAVASKQIVVINEFIACLNSRCVPSQYDR
                     FFYKDRPYIFSRKSPIKG"
     gene            complement(4820..5065)
                     /locus_tag="ACL3EZ_001957"
     CDS             complement(4820..5065)
                     /locus_tag="ACL3EZ_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000513491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0393473.1"
                     /translation="MGIYGHKTIAMKHFFAGIGEIHFLLFLLYLSMSASPIIGLVIGY
                     TKINLINSIIIALGMILALILVLSRVYRKYFYRDDDD"
     gene            complement(5046..5171)
                     /locus_tag="ACL3EZ_001958"
     CDS             complement(5046..5171)
                     /locus_tag="ACL3EZ_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0393474.1"
                     /translation="MATITNALNIATTVAEVFSLGGAIAYGLDIVDGKFDGYLWA"
     gene            complement(5544..5756)
                     /locus_tag="ACL3EZ_001959"
     CDS             complement(5544..5756)
                     /locus_tag="ACL3EZ_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000989850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0393475.1"
                     /translation="MMVVLISVIVAFLYHKITEYVNNRKIDIVIFLSLLISHFIWNYY
                     FLPIEILIAISGANLLLSFLKKLQTK"
     gene            complement(5910..>6568)
                     /locus_tag="ACL3EZ_001960"
     CDS             complement(5910..>6568)
                     /locus_tag="ACL3EZ_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0393476.1"
                     /translation="AIINDTEYFLLIFLAFIYSIVSLPLYSVKNKIVSICLAINSILL
                     MSFPILINKFFPESFLTYTVLISVFILELAIFHLIRKDFDIKLTNEYKKISQFRSKVS
                     QSPWIKYLEISSFILTIFPSILYGTVDNHVLTLIFLIKICADTTIKFLFIRLFDTSTL
                     MKRRIFFLFALDVIAYLFLGYLLVIQKAGYLFSILLLFSNFSVPFIKEKEYELFKNKK
                     "
BASE COUNT         2416 a         1141 c          825 g         2186 t
ORIGIN      
        1 ccaacacacg atgatgtgta tttttcgaat cttatctaca ttactcatct tactgttgca
       61 gatatgaatc catcccaagg ataagggttc ccgttaatat cacaacctct attaagaaca
      121 ccatatccaa tacagtaagc tattttccct gctgctgtag ccaatacacc tgctgctgca
      181 ccaataagcc agcctccaag acctccaacc ttaatatagt ttattagttt tttggttaaa
      241 actgcagctc cagctaatgc tataaaagtt cctggactca tagctaaagc tgcgcaaatt
      301 ccttgacaag cacgcttgct taaataatct cccccatcaa gatacatcat tacttcttca
      361 tcaatcacaa cataattatt tggtaataca agttccattt gttttctcct ccttagttga
      421 aattgtttca tttgttttac aaataggacg aacttaaact atctttttat tactcagtaa
      481 taatttccga gatttcattt tatgatactc tctattcata cagaaatcaa aattttgcct
      541 taaccaactt gtataataga aaaaatctaa ttgattgatt ctgatgaggt gtatcctaat
      601 tttatcaacc ttttcttgcc agttgttatt gttactaata gacatttcat acatcagtaa
      661 ctcgacaaga cctgtacaca gaagggtgtt atgagaatct tcgatttttt tcaaaatatc
      721 ctcaaaaagt tcactatccg ttaaaaaggt ggattggttc atcgcatcat acagctgaag
      781 agacattaag tcagaataac ttagctctga tttttgtatc ttatccttta acgttttcgt
      841 caaatcgctt tcaaacgaat cttctttttc ccatttattt tgattaaaaa gaaattccgt
      901 cttattaaaa acgagatgat tgatatccat tatagtccag aaaaatattg tagtaagcat
      961 gatgattgca aaaggaattt ttaaaataaa tactaggata atagcaattt caagaataaa
     1021 actccatata atcctagatc ttaaatcatc aggcgacaaa cttttacgat ggaatgaaaa
     1081 atagggcgag aatctcacat tcactttttt ccttcttata aaaataaagg gaaaaatctt
     1141 aataagacct tctttcttgt ataaatcttt caatgcgtat agtatgtcta aaactatttt
     1201 tgataaaatc aaactacaga aagcaagact catactaatc acaaaatcaa ggggagattc
     1261 tagattcaat agtaagttat tcactaggac atgcaactct agccacaaga caaaaagagg
     1321 gagcattagt aagaaaacaa ttagtttacg tatcataatt ttacagtgtc cttatcattt
     1381 tcttaatttt ggataaatca tcattgctat gattaaaatc aaaaaaacga cattcatcca
     1441 aataatcaac ttttttattt cttcgctaac aaaatcatag gctaaaaaag ttatggatga
     1501 tataaataga catacaaaaa aaataataac aaaaattttt tccattttaa tacccatatc
     1561 tagttaccac aaggcgttta aatttgggtc tctcctattt acatcattgt tggcccagat
     1621 tgttgtaata gcatcgccaa ttgacatcca agctgcaaat ccattaatag cagacagtgc
     1681 aaatcctgcc actctatttg caactcgtac cccaacatat cttgcagctg ctccagcaat
     1741 tgcgcttgta actcgccgca aaccataatt acgaatataa tttctaacta gactgattgc
     1801 tcctccacct aaaacaccat taaaagctat attaatggct gttgcaacag gccatctcgg
     1861 aatagaaaat cccccatcaa gatacatcat ctcttcttgc tcaagaacaa cataattatt
     1921 tggtaatacg agttccattt attttctcct tttttattaa gtatggttag gatggtttcc
     1981 taacaagtaa tcgtcgactg tgtttttatc acttagctac ctagataaga tatcctttct
     2041 ctaccttatt tgtttttata ggttacctaa ggtttaaaac caattattgt ttgaaactta
     2101 acagttctaa accactagca ataaatgatt gcgaactcac taatactatt tcaaaattta
     2161 tttttttgac ttagtaacgc aattccaatt agcaatacac ctattataaa taaaagtatt
     2221 tcccaaaatt tattatccgt gttaatgaga ggtataagat acatactgac taatatgcaa
     2281 cttgccccta taatagcaaa tgttattcta gttttatctc ctaattgaaa catgtttgat
     2341 ccctatatac acttcaagca aaagttggat ttctgaaata gctaaagata aagataatgg
     2401 ttgcgagcta tttaaactat catcaatatt ctgctcgatt aaaacaaagt ctggtcttac
     2461 ctctaaaatt ttatttaaca ttgattcata tttatttttt tcattataat gccgtaaata
     2521 tagatttaat tttataacat ccaacatacc ataaagtgat attggatgat ttattttttt
     2581 aaatcgctta acttctaata aatcaatttg ttcacgcacg ctctctgaaa gatatggctt
     2641 gatcaaactg atataagata aagccacgca tggcaactca gattttgatt gcaatttcca
     2701 aatttcatga taatcctgaa gattaaactc acaattcttc ttagattcca gtattgttag
     2761 tacctttgat tttaacagaa ataattgttg attctcaatt ctataaagtt tttgtactaa
     2821 tgctatgata atagaaaatg aaataagagg caaaagcaac ggtttgtcat acacaaaagt
     2881 aaagaaaaaa tagtatgaaa ttagtgttgt aaagtacaag aagtagtaaa atttaaacag
     2941 attcttagtt gtttgactct ccttataaaa cactgctatt cctggactaa atcccattag
     3001 ttggtgaaag agaattcgat agtatttcct agctcctata atgatcacaa atataaaata
     3061 aaaataaatt ggtcttaatt tacaaaagat tgaggaaact agtaatagca aagtatgtaa
     3121 gcattgagac aaaatataga ataacggtat cgccaataca aaggttaaga tggcatgaga
     3181 gggagttcct aagatgtcca attttataaa tactgggctg acacaaaata tcgtgcttat
     3241 aagcagtaaa attattaaaa ttgtgtcaaa aaaataacgc ttatttttca ttagtctact
     3301 ttccattgtt aaataatact actgctaaca ccaagccaac ttagcacatt gcatcaccta
     3361 atcctgcgct acttgtccat aatcctttaa tgtttctact aaaattattc caatttcccc
     3421 catcaagata gcttatttat cctagacaat gcctactgca acagtataaa taagattcat
     3481 cagccatctt ttctggcaat catatgggta gcctaatgat atttctagtt actcaaaaat
     3541 atctagctat actagagtta tttctaatcc ctaggacact tgttaatcca aatgtaacaa
     3601 attttcaccc cttaatagga ctctttctgg aaaaaatata aggtctatct ttataaaaaa
     3661 atctatcata ttgggatggc acgcatctgg aatttaaaca agctataaat tcatttataa
     3721 ctactatttg tttagaggca acagcatctt gtataccgcc ctcgaaagaa ccatcttgta
     3781 attccgaaat atttttgttt aaatattgtt ttgacaaatc tcttaatgct tcattatcgt
     3841 aaatgattcc caaaaatcca accttatata gtaaataatt taaacttaca aagtaattga
     3901 atcccatagt atatttttct ttataaagca aaggtaaaac tttataaaaa atatctaagt
     3961 caacctcact ctgattctga agcaagtagg agtcaagcaa attttcaaaa atagctaaca
     4021 atatgattgg tgtaaagttt ttgtattcac atgtcaagta ttctgagtat cgtgcagatg
     4081 atatttcttt tatataactt tttgaaagca agattttttc aaattcatca tctattatta
     4141 atcttctatt tccaatccaa gcggtattac cacccaaata agattgtgca aatagcaata
     4201 tgtaagaaaa tatgaacgta aatactgaaa gaggtagaat tctatgcgta aaaaaataga
     4261 cgataatggt agccaggagt aaagatatct ctcgtgacaa tcgaattctt ttcagcatct
     4321 tttttaacag tccgtaaggt tgtccttggc aatattcttg aactaaatta atcggaatga
     4381 catctctcac catttctgga aagtagagta agtttatagg ttgaaatctc caactcccat
     4441 cataagtaaa tggatataga accaaatact taaaagattt ttttcttata aacttaatta
     4501 tcacaatatg aatgactgtt gcaatgaagt atattaaata taaaagtaaa accgccatca
     4561 atatacttac aaaaatcccc ttggactcaa tcaatggaaa ataaaatatt gcaactagaa
     4621 gcgaataaag tcccgctaat aaatatttct gatcatcttt cattcaaaac accatattat
     4681 ttactaagaa tacatcaata caatagagca actctgtaag tcaatatttg ataaagcaaa
     4741 gctttaacct cttccccaga cgttagcttt tcttcaaccc actacagttg acaaggagcc
     4801 caaattattg ataaaaactt tagtcatcat cgtctctata aaaatatttt ctatacactc
     4861 ttgataatac caaaattaat gccaatatca taccaagagc tataataata gaatttatta
     4921 gatttatttt agtatatcca atcactagtc caataattgg actagcagac atgcttagat
     4981 ataataaaaa taacaaaaaa tgaatttcac caattcctgc aaaaaaatgt ttcatagcta
     5041 tagttttatg cccataaata cccatcaaat ttaccgtcta cgatatctaa accatatgca
     5101 atggctcctc ctaatgagaa gacttcagca acagtagtcg caatattaag agcattagta
     5161 atagttgcca tactaactcc accaatatat cttgttatag cacttagtta cctagataag
     5221 atatccttta gcttgcttcc aaaatttaag tctacaccta taatatgagt tcatattagt
     5281 actgctaaat cctatctata gtaatgtcaa acacctaaat aaagtcatct ctccaattca
     5341 ttcaagaaat gaagaaaggc aaaaaatctt taaaataaga aaagtgcata ttatcaggtg
     5401 ttcaaaaatc ttgataatat gcgttatata atagaaaaat ttactcaatt tcattttcaa
     5461 attgagtttt ttcccagcct catttttaat ttatatcttc aatagaatct aatgaccgag
     5521 ctactgtatt acacagatta atattattta gtctgtaatt tttttaaaaa acttaatagt
     5581 aaatttgctc cactgattgc tatcaatatt tcaattggta aaaaatagta attccaaata
     5641 aaatgagaaa tcagcaatga tagaaaaata acaatatcaa ttttcctgtt gttgacatac
     5701 tctgtaattt tatgatacag gaatgcaaca ataactgaaa ttaaaacaac catcataata
     5761 ctattatcct atccttctca ctaactctat ttccaaaatt taatttttgg gggacttagt
     5821 aatgaaatta caattaacaa cacacctaaa ataaataaaa atatctccca aactttattc
     5881 tcagttttaa taaagctacc atatctatct catttcttat ttttaaataa ttcgtattcc
     5941 ttttctttga taaatggaac tgaaaaatta gagaaaagaa gtaaaatcga aaacagatat
     6001 cctgcttttt gaatcactaa aagatatcct aaaaataagt aagctataac atccaatgcg
     6061 aaaagaaaaa atattctcct cttcattaaa gtacttgtgt caaataatct gatgaataaa
     6121 aattttatcg tggtatctgc acaaattttt atcaaaaaga taagagtcag tacatgatta
     6181 tcaactgtac cataaagaat agatggaaat atagttaata taaaactaga aatctctaaa
     6241 tattttatcc aaggagattg agacaccttg cttctaaact gactaatttt cttatattcg
     6301 ttagtcaatt taatatcaaa atctttccta attaaatgaa agattgctaa ctctaggata
     6361 aaaacactta ttaatacggt ataagtcaaa aaactttctg ggaaaaactt attgattaaa
     6421 atggggaaac tcattaacag aatcgaattt atggctagac agatagatac tattttattt
     6481 ttcacagaat atagaggtag tgatactatt gagtagataa aagctaaaaa aataagcaaa
     6541 aaatactccg tgtcatttat aatcgccc
//
LOCUS       DBEJHE010000055         6471 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC4 isolate 671759
            SAMN38261586-rid24793303.denovo.55, whole genome shotgun sequence.
ACCESSION   DBEJHE010000055 DBEJHE010000000
VERSION     DBEJHE010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261586
            Sequence Read Archive: SRR26833752
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 6471)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6471)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576136.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576136.1
            Genome Coverage       :: 109x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 19:48:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,067
            CDSs (total)                      :: 2,029
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 131
            CDSs (without protein)            :: 131
            Pseudo Genes (ambiguous residues) :: 0 of 131
            Pseudo Genes (frameshifted)       :: 64 of 131
            Pseudo Genes (incomplete)         :: 59 of 131
            Pseudo Genes (internal stop)      :: 46 of 131
            Pseudo Genes (multiple problems)  :: 32 of 131
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6471
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261586-rid24793303.denovo.55"
                     /strain="GPSC4"
                     /isolate="671759"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            110..310
                     /locus_tag="ACL3EZ_001961"
     CDS             110..310
                     /locus_tag="ACL3EZ_001961"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HGR0393477.1"
                     /translation="MNLTFLGLCIACMGVSVGEGLLMNGLFKSVARQPDMLSEFRSLM
                     FLGVAFIEGTFFVTLVFSFIIK"
     gene            345..1061
                     /gene="atpB"
                     /locus_tag="ACL3EZ_001962"
     CDS             345..1061
                     /gene="atpB"
                     /locus_tag="ACL3EZ_001962"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HGR0393478.1"
                     /translation="MEESINPIISIGPVIFNLTMLAMTLLIVGVIFVFIYWASRNMTL
                     KPKGKQNVLEYVYDFVIGFTEPNIGSRYMKDYSLFFLCLFLFMVIANNLGLMTKLQTI
                     DGTNWWSSPTANLQYDLTLSFLVILLTHIESVRRRGFKKSIKSFMSPVFVIPMNILEE
                     FTNFLSLALRIFGNIFAGEVMTSLLLLLSHQAIYWYPVAFGANLAWTAFSVFISCIQA
                     YVFTLLTSVYLGNKINIEEE"
     gene            1075..1569
                     /gene="atpF"
                     /locus_tag="ACL3EZ_001963"
     CDS             1075..1569
                     /gene="atpF"
                     /locus_tag="ACL3EZ_001963"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045263 - proton-transporting ATP
                     synthase complex, coupling factor F(o) [Evidence IEA];
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HGR0393479.1"
                     /translation="MHVTVGELIGNFILITGSFILLLVLIKKFAWSNITGIFEERAEK
                     IASDIDRAEEARQKAEVLAQKREDELAGSRKEAKTIIENAKETAEQSKANILADAKLE
                     AGHLKEKANQEIAQNKVEALQSVKGEVADLTISLAGKIISQNLDSHAHKALIDQYIDQ
                     LGEA"
     gene            1569..2105
                     /locus_tag="ACL3EZ_001964"
     CDS             1569..2105
                     /locus_tag="ACL3EZ_001964"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HGR0393480.1"
                     /translation="MDKKTVKVIEKYSMPFVQLVLEKGEEDRIFSDLTQIKQVVEKTG
                     LPSFLKQVAVDESDKEKTIAFFQDSVSPLLQNFIQVLAYNHRANLFYDVLVDCLNRLE
                     KETNRFEVTITSAHPLTDEQKTRLLPLIEKKMSLKVRSVKEQIDESLIGGFVIFANHK
                     TIDVSIKQQLKVVKENLK"
     gene            2120..3625
                     /gene="atpA"
                     /locus_tag="ACL3EZ_001965"
     CDS             2120..3625
                     /gene="atpA"
                     /locus_tag="ACL3EZ_001965"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_component: GO:0045262 - plasma membrane
                     proton-transporting ATP synthase complex, catalytic core
                     F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HGR0393481.1"
                     /translation="MAINAQEISALIKQQIENFKPNFDVTETGVVTYIGDGIARAHGL
                     ENVMSGELLNFENGSYGMAQNLESTDVGIIILGDFTDIREGDTIRRTGKIMEVPVGES
                     LIGRVVDPLGRPVDGLGEIHTDKTRPVEAPAPGVMQRKSVSEPLQTGLKAIDALVPIG
                     RGQRELIIGDRQTGKTTIAIDTILNQKDQDMICIYVAIGQKESTVRTQVETLRQYGAL
                     DYTIVVTASASQPSPLLFLAPYTGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLL
                     LRRPPGREAFPGDVFYLHSRLLERSAKVSDELGGGSITALPFIETQAGDISAYIATNV
                     ISITDGQIFLGDGLFNAGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRIDLASYREL
                     EAFTKFGSDLDAATQAKLNRGRRTVEVLKQPVHKPLPVEKQVTILYALTHGFLDTVPV
                     DDIVRFEEEFHAFFDAQHPEILETIRDTKDLPEEAVLDAAITEFLNQSSFQ"
     gene            3641..4519
                     /locus_tag="ACL3EZ_001966"
     CDS             3641..4519
                     /locus_tag="ACL3EZ_001966"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HGR0393482.1"
                     /translation="MAVSLNDIKTKIASTKNTSQITNAMQMVSAAKLGRSEEAARNFQ
                     VYAQKVRKLLTDILHGNGAGASTNPMLISRSVKKTGYIVITSDRGLVGGYNSSILKAV
                     MELKEEYHPDGKGFEMICIGGMGADFFKARGIQPLYELRGLADQPSFDQVRKIISKTV
                     EMYQNELFDELYVCYNHHVNTLTSQMRVEQMLPIVDLDPNEADEEYSLTFELETSREE
                     ILEQLLPQFAESMIYGAIIDAKTAENAAGMTAMQTATDNAKKVINDLTIQYNRARQAA
                     ITQEITEIVAGASALE"
     gene            4605..6011
                     /gene="atpD"
                     /locus_tag="ACL3EZ_001967"
     CDS             4605..6011
                     /gene="atpD"
                     /locus_tag="ACL3EZ_001967"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_component: GO:0045262 - plasma membrane
                     proton-transporting ATP synthase complex, catalytic core
                     F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HGR0393483.1"
                     /translation="MSSGKIAQVIGPVVDVLFAAGEKLPEINNALVVYKNDERKTKIV
                     LEVALELGDGMVRTIAMESTDGLTRGMEVLDTGRPISVPVGKETLGRVFNVLGDTIDL
                     EAPFTEDAERQPIHKKAPTFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLVQ
                     LGIYPAVDPLASSSRALAPEIVGEEHYAVAAEVKRVLQRYHELQDIIAILGMDELSDE
                     EKTLVARARRIQFFLSQNFNVAEQFTGQPGSYVPVAETVRGFKEILDGKYDHLPEDAF
                     RGVGSIEDVIAKAEKMGF"
     gene            6022..6441
                     /locus_tag="ACL3EZ_001968"
     CDS             6022..6441
                     /locus_tag="ACL3EZ_001968"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HGR0393484.1"
                     /translation="MAQLTVQIVTPDGLVYDHHASYVSVRTLDGEMGILPRHENMIAV
                     LAVDEVKVKRIDDKDHVNWIAVNGGVIEIANDMITIVADSAERARDIDISRAERAKLR
                     AERAIEEAQDKHLIDQERRAKIALQRAINRINVGNRL"
BASE COUNT         1924 a         1212 c         1431 g         1904 t
ORIGIN      
        1 aaatggaaat aatttttatt aaacgcttcc aatagcggtt aaaagttgac aaatttaaat
       61 tttaggacta cactaagtaa gtaaatttta ttttaaagga gaatttgtta tgaatttaac
      121 atttttaggc ttatgtattg cctgtatggg cgtatctgtc ggtgaaggtt tattgatgaa
      181 tggactgttt aaatcagtag cacgccaacc agatatgctt tctgagtttc gtagtttgat
      241 gtttttaggt gttgccttta ttgaaggaac tttctttgta actcttgtct tctcatttat
      301 tatcaaataa atacatggaa cgagaagaaa agggaggatt ttagatggaa gaaagtatta
      361 atccaatcat ctctattggt cctgttatct tcaatctgac tatgttagcc atgactttgt
      421 tgattgtggg agttattttt gtctttattt attgggcaag ccgcaatatg accttgaaac
      481 ccaaaggaaa gcaaaatgta cttgagtatg tctatgactt tgttattgga tttacagaac
      541 ctaacattgg ttcgcgctac atgaaagatt actcactctt tttcctttgt ttattccttt
      601 tcatggtgat tgccaataac cttggcttaa tgacaaagct tcaaacgatc gatgggacta
      661 actggtggag ttcgccaacc gctaatttac agtatgactt aaccttatct tttcttgtca
      721 ttttgttgac acatatagaa agcgttcgtc gtcgtggatt taaaaaaagt ataaaatctt
      781 ttatgagtcc tgtttttgtc ataccgatga atatcttgga agaatttaca aacttcttat
      841 ctttggcttt gcggattttt gggaatatct ttgcaggaga ggtcatgacg agtttgttac
      901 ttcttctttc ccaccaagct atttattggt atccagtagc ctttggagct aatttggctt
      961 ggactgcatt ttctgtcttt atttcctgca tccaagctta tgtttttact cttttgacat
     1021 ctgtgtattt agggaataag attaatattg aagaggaata gaaaggagta actgatgcac
     1081 gtaacagtag gtgaattaat tggtaatttt attttaatca ctggctcttt tattcttttg
     1141 ctagtcttga ttaaaaaatt tgcatggtct aatattacag gcattttcga agaaagagct
     1201 gaaaaaattg cttcagatat tgacagagct gaagaagccc gtcaaaaagc agaagtattg
     1261 gctcaaaaac gcgaagatga attggctggt agccgtaaag aagctaagac aatcattgaa
     1321 aatgcaaagg aaacagctga gcaaagtaag gctaatatct tagcagatgc taaactagaa
     1381 gcaggacact taaaagaaaa agccaatcaa gaaattgctc aaaataaagt agaagcttta
     1441 cagagtgtta agggtgaggt cgcagatttg accatcagct tagctggtaa aatcatctca
     1501 caaaaccttg acagtcatgc ccataaagca ctcattgatc agtatatcga tcagctagga
     1561 gaagcttaat ggacaagaaa acagtaaagg taattgaaaa atacagcatg ccttttgtcc
     1621 aattggtact tgaaaaagga gaagaagacc gtatcttttc agacttgact caaatcaagc
     1681 aagttgttga aaaaacaggt ctgccttctt ttttaaaaca agtggcagta gacgagtcgg
     1741 ataaggaaaa aacaattgct tttttccaag attctgtgtc gcctttatta caaaacttta
     1801 tccaggttct ggcctacaat cacagagcaa atctttttta tgatgtgctt gtagattgct
     1861 tgaaccgact tgaaaaagaa acaaatcgat ttgaagtgac gattacgtct gctcatcctc
     1921 taactgatga acagaagact cgtttgctcc ctttgattga gaaaaaaatg tctctgaaag
     1981 taaggagtgt aaaagaacaa atcgatgaaa gtctcattgg tggttttgtc atttttgcca
     2041 atcacaagac aattgatgtg agtattaaac aacaacttaa agttgttaaa gaaaatttga
     2101 aatagaaagt ggtgttcttt tggcaattaa cgcacaagaa atcagcgctt taattaagca
     2161 acaaattgaa aatttcaaac ccaattttga tgtgactgaa acaggtgttg taacctatat
     2221 cggggacggt atcgcgcgtg ctcatggcct tgaaaatgtc atgagtggag agttgttgaa
     2281 ttttgaaaac ggctcttatg gtatggctca aaacttggag tcaacagacg ttggtattat
     2341 catcctaggt gactttacag atatccgtga aggcgataca atccgccgta cagggaaaat
     2401 catggaagtc cctgtaggtg aaagtttgat tggtcgtgtt gtggatccgc ttggtcgtcc
     2461 agttgacggt cttggagaaa tccacactga taaaactcgt ccagtagaag caccagctcc
     2521 tggtgttatg caacgtaagt ctgtttcaga accattgcaa actggtttga aagctattga
     2581 cgcccttgta ccgattggtc gtggtcaacg tgagttgatt atcggtgacc gtcagacagg
     2641 gaaaacaacc attgcgattg atacaatctt gaaccaaaaa gatcaagata tgatctgtat
     2701 ctacgtcgcg attggacaaa aagaatcaac agttcgtacg caagtagaaa cacttcgtca
     2761 gtacggtgcc ttggactaca caatcgttgt gacagcctct gcttcacaac catctccatt
     2821 gctcttccta gctccttata ctggggttgc tatggcggaa gaatttatgt atcaaggtaa
     2881 gcatgttttg attgtatacg atgatctatc aaaacaagcg gtagcttatc gtgaactatc
     2941 gctcttgctt cgtcgtcctc caggtcgtga agccttccca ggggatgttt tctatctcca
     3001 cagccgtttg cttgagcgct cagctaaagt ttctgatgaa cttggtggtg gatcaattac
     3061 agccctacca tttatcgaga cacaagcagg agatatctca gcctatatcg caaccaacgt
     3121 gatttctatc actgatggac aaatcttcct tggcgatggc ctcttcaatg caggtattcg
     3181 tccagccatc gatgcgggtt catctgtatc tcgtgtaggt ggttctgcac aaatcaaagc
     3241 catgaagaag gttgctggta cacttcgtat cgaccttgct tcataccgtg agttggaagc
     3301 ctttactaag tttggttctg acttggacgc agcaacacag gctaagttga accgtggacg
     3361 tcgtaccgtt gaggtcttga aacaacctgt tcacaaacca ttacctgttg agaaacaagt
     3421 aaccattctt tatgctttga cacatggttt cttggatact gttccagtag atgatattgt
     3481 tcgtttcgag gaagagttcc atgccttctt tgatgctcaa catccagaga ttttggaaac
     3541 cattcgtgat acaaaagact tgccagaaga agcagtcttg gatgctgcga ttacagagtt
     3601 tctcaatcaa tctagcttcc aataagaata gaggtgtcag atggcagtgt ctctaaatga
     3661 tattaaaaca aaaatcgcct caacaaaaaa tacgagtcaa atcactaatg ccatgcaaat
     3721 ggtatcggct gctaagttag gtcgctctga agaagctgct cgcaacttcc aagtttacgc
     3781 tcagaaagtg cgtaaacttt tgacagatat ccttcatggt aatggagctg gtgcttcaac
     3841 taatccgatg ttgattagcc gttctgtgaa gaagacaggc tatatcgtta tcacttcaga
     3901 ccgcggtttg gttggaggtt ataattcctc tattttgaaa gctgttatgg agttgaaaga
     3961 agaataccac ccagacggta aaggttttga aatgatctgt atcggtggga tgggagctga
     4021 tttctttaag gctcgcggta ttcaaccact ttatgaatta cgtggcttgg cagaccaacc
     4081 tagctttgat caagttcgta agattatttc aaaaactgtt gaaatgtacc aaaatgaact
     4141 ctttgatgag ctttatgttt gctacaacca ccatgtcaat acgctaacca gtcaaatgcg
     4201 tgtggaacaa atgcttccga ttgttgactt ggatccaaat gaagcggatg aagagtacag
     4261 cttgactttt gaattggaaa ccagccgaga agaaattctg gagcagttgt tgcctcagtt
     4321 tgcagaaagt atgatttacg gtgccattat cgatgccaag acagctgaga atgctgcggg
     4381 tatgacagcc atgcaaacag cgacagataa tgctaagaaa gtcatcaatg atttgacaat
     4441 tcagtataac cgtgccagac aggcggcgat tacacaagaa attacagaaa tcgtagcagg
     4501 tgctagtgcc ttagaatagg ctctagtcca gctcgtatga aaatgaactt aggacctagt
     4561 tgagctagga accgacagta tcttatatag aataggagaa ggagatgagt tcaggtaaaa
     4621 ttgctcaggt tatcggtccc gttgtagacg ttttgtttgc agcaggggaa aaacttcctg
     4681 agattaacaa tgcacttgtc gtctacaaaa atgacgaaag aaaaacaaaa atcgtccttg
     4741 aagtagcctt ggagttagga gatggtatgg ttcgtactat cgccatggaa tcaacagatg
     4801 ggttgactcg tggaatggaa gtattggaca caggtcgtcc aatctctgta ccagtaggta
     4861 aagaaacttt gggacgtgtc ttcaacgttt tgggagatac cattgatttg gaagctcctt
     4921 ttacagaaga cgcagagcgt cagccaattc ataaaaaagc tccaactttt gatgagttgt
     4981 ctacctcttc tgaaatcctt gaaacaggga tcaaggttat tgaccttctt gccccttacc
     5041 ttaaaggtgg taaagttgga cttttcggtg gtgccggagt tggtaaaacc gtcttaatcc
     5101 aagaattgat tcacaacatt gcccaagagc acggtggtat ttcagtattt actggtgttg
     5161 gggaacgtac tcgtgagggg aatgaccttt actgggaaat gaaagaatca ggcgttatcg
     5221 agaaaacagc catggtcttt ggtcagatga atgagccacc aggagcacgt atgcgtgttg
     5281 cccttactgg tttgacaatc gctgaatact tccgtgatgt ggaaggccaa gacgtgcttc
     5341 tctttatcga taatatcttc cgtttcactc aggctggttc agaagtatct gcccttttgg
     5401 gtcgtatgcc atcagccgtt ggttaccaac caacacttgc tacggaaatg ggtcaattgc
     5461 aagaacgtat cacatcaacc aagaagggtt ctgtaacctc tatccaggct atctatgtgc
     5521 cagcggatga ctatactgac ccagcgccag caacagcctt cgctcacttg gattcaacaa
     5581 caaacttgga acgtaaattg gtacaattgg gtatctaccc agccgttgac ccacttgctt
     5641 caagctcacg tgccttggca cctgaaatcg ttggagaaga gcactatgca gttgctgctg
     5701 aagtaaaacg tgtccttcaa cgttaccatg aattgcaaga tatcattgct atccttggta
     5761 tggatgagct ttctgatgaa gaaaagacct tggttgctcg cgcccgtcgt atccagttct
     5821 tcttgtcaca aaacttcaac gttgcggaac aatttactgg tcagccaggt tcttatgttc
     5881 cagttgctga aactgtacgt ggctttaagg aaatccttga tggtaaatac gaccacttgc
     5941 cagaagatgc cttccgtggt gtaggttcta tcgaagatgt gattgcaaaa gctgaaaaaa
     6001 tgggatttta agaggtgacc tatggctcag ttaactgtcc agatcgtgac accagatggt
     6061 ctcgtctatg atcaccatgc cagctatgta tcggttcgaa ctctggatgg tgagatgggg
     6121 atcttgccac gacatgaaaa tatgattgcg gttttagcag ttgatgaagt aaaggtaaaa
     6181 cgtatcgatg ataaagatca cgtgaactgg attgcagtaa acggtggcgt tattgaaatt
     6241 gccaatgata tgatcacaat cgtcgctgac tctgcagaac gtgctcgtga tatcgatatt
     6301 agccgtgcag aacgtgccaa acttcgtgca gaacgtgcaa ttgaagaagc acaagacaaa
     6361 catttgattg accaagaacg tcgtgctaag attgctttgc aacgtgccat taaccgtatt
     6421 aatgtcggaa atagactata agaaaaaatg aacttgaaaa taccaagttc a
//
LOCUS       DBEJHE010000056         6329 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC4 isolate 671759
            SAMN38261586-rid24793303.denovo.56, whole genome shotgun sequence.
ACCESSION   DBEJHE010000056 DBEJHE010000000
VERSION     DBEJHE010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261586
            Sequence Read Archive: SRR26833752
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 6329)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6329)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576136.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576136.1
            Genome Coverage       :: 109x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 19:48:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,067
            CDSs (total)                      :: 2,029
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 131
            CDSs (without protein)            :: 131
            Pseudo Genes (ambiguous residues) :: 0 of 131
            Pseudo Genes (frameshifted)       :: 64 of 131
            Pseudo Genes (incomplete)         :: 59 of 131
            Pseudo Genes (internal stop)      :: 46 of 131
            Pseudo Genes (multiple problems)  :: 32 of 131
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6329
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261586-rid24793303.denovo.56"
                     /strain="GPSC4"
                     /isolate="671759"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            1..310
                     /locus_tag="ACL3EZ_001969"
                     /pseudo
     CDS             1..310
                     /locus_tag="ACL3EZ_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558102.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            465..665
                     /locus_tag="ACL3EZ_001970"
                     /pseudo
     CDS             465..665
                     /locus_tag="ACL3EZ_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000226586.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            690..1106
                     /locus_tag="ACL3EZ_001971"
     CDS             690..1106
                     /locus_tag="ACL3EZ_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transmembrane domain-containing protein"
                     /protein_id="HGR0393485.1"
                     /translation="MKAALDSLKDVKANASDSKPAQDKKDAKQGTEDSKDSDKMTETN
                     SVPAGVIVVSLLALLGVIAFWLIRRKKESEIQQLSTELIKVLGQLDAEKADKKVLAKA
                     QNLLQETLDFVKEENGSAETETKLVEELKAILDKLK"
     gene            1337..2044
                     /gene="ccdA2"
                     /locus_tag="ACL3EZ_001972"
     CDS             1337..2044
                     /gene="ccdA2"
                     /locus_tag="ACL3EZ_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004237834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HGR0393486.1"
                     /translation="METIVFLISVFLAGVLSFFSPCIFPLLPVYAGILLDDQESAKSF
                     SLFGRKVLWSGLIRTLCFIAGISLIFFILGFGAGYFGHILYANWFRYVMGAIIIILGL
                     HQMEIFHLKKLEVQKSFTFKKSDSNRYWSAFLLGITFSFGWTPCIGPVLSSVLALAAS
                     GGNGAWQGAIYTLIYTLGMALPFLVLALASGLVMPYFSKIKRHMMLLKKIGGFLIVLM
                     GILLLLGQVNVLAGIFE"
     gene            2055..2612
                     /gene="sdbB"
                     /locus_tag="ACL3EZ_001973"
     CDS             2055..2612
                     /gene="sdbB"
                     /locus_tag="ACL3EZ_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     lipoprotein SdbB"
                     /protein_id="HGR0393487.1"
                     /translation="MKKVMFAGLSLLSLVVLMACGEEETKKTQAAQQPKQQTTVQQIS
                     VGKDAPDFTLQSMDDKEVKLSDFKGKKVYLKFWASWCGPCKKSMPELMELAAKPDRDF
                     EILTVIAPGIQGEKTVEQFPQWFQEQGYKDIPVLYDTKATTFQAYQIRSIPTEYLIDS
                     QGKIGKIQFGAISNADAEAAFKEMN"
     gene            2986..4377
                     /locus_tag="ACL3EZ_001974"
     CDS             2986..4377
                     /locus_tag="ACL3EZ_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001020339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HGR0393488.1"
                     /translation="MNIFRTKNVSLDKTEMHRHLKLWDLILLGIGAMVGTGVFTITGT
                     AAATLAGPALVISIVISALCVGLSALFFAEFASRVPATGGAYSYLYAILGEFPAWLAG
                     WLTMMEFMTAISGVASGWAAYFKGLLSQYGIAFPQALNGTFNPQAGTFVDLLPILVLV
                     LVTSLVLLNAKAALRFNSILVILKFSALALFVLVGIWNIKFDNWSNFAPYGFGQIYGA
                     STGIMAGASLMFFGFLGFESISMAVDEVKTPQKNIPRGIVLSLSIVTILYALVTLVLT
                     GVVHYSHLNVDDAVAFALRSVGISWAANYVSLVAILTLITVCISMTYALSRMIYSLAR
                     DGLVPAAFKELTKTSKIPKNATILTGLASAVAAGMFPLASIAAFLNICTLAYLIMLAY
                     GLIRLRKEKGMPKAGEFKTPLVPLLPILSIIICLSFMLQYNMNTWIAFLVALLVGSII
                     YFTYGYKHSTIEE"
     gene            4520..5437
                     /gene="adcAII"
                     /locus_tag="ACL3EZ_001975"
     CDS             4520..5437
                     /gene="adcAII"
                     /locus_tag="ACL3EZ_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding lipoprotein AdcAII"
                     /protein_id="HGR0393489.1"
                     /translation="MKKQNLFLVLLSVFLLCLGACGQKESQTGKGMKIVTSFYPIYAM
                     VKEVSGDLNDVRMIQSSSGIHSFEPSANDIAAIYDADVFVYHSHTLESWAGSLDPNLK
                     KSKVKVLEASEGMTLERVPGLEDVEAGDGVDEKTLYDPHTWLDPEKAGEEAQIIADKL
                     SEVDREHKETYQKNAQAFIKKAQELTKKFQPKFEKATQKTFVTQHTAFSYLAKRFGLN
                     QLGIAGISPEQEPSPRQLTEIQEFVKTYKVKTIFTESNASSKVAETLVKSTGVGLKTL
                     NPLESDPQNDKTYLENLEENMSILAEELK"
     gene            5445..>6329
                     /gene="phtB"
                     /locus_tag="ACL3EZ_001976"
     CDS             5445..>6329
                     /gene="phtB"
                     /locus_tag="ACL3EZ_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtB"
                     /protein_id="HGR0393490.1"
                     /translation="MKINKKYLAGSVAVLALSVCSYELGRYQAGQDKKESNRVAYIDG
                     DQAGQKAENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISE
                     ELLMKDPNYQLKDSDIVNEIKGGYVIKVNGKYYVYLKDAAHADNIRTKEEIKRQKQER
                     SHNHNSRADNAVAAARAQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKNEL
                     SASELAAAEAYWNGKQGSRPSSSSSYNANPAQPRLSENHNLTVTPTYHQNQGENISSL
                     LRELYAKPLSERHVESDGL"
BASE COUNT         1938 a         1130 c         1343 g         1918 t
ORIGIN      
        1 gccttatttc ttaagaattt taatagatta aagcacctag cacctgttta gattgatgaa
       61 acaggattcg atacttattt ttatcgagaa tatggtcgct cattaaaaag tcagttaata
      121 agaggcaaag tatctggaag aagatatcag aggatttctt tggttgcagg tctaacaaat
      181 gaatggtgag ttaatcgctc caatggctta cgaagagacg atgacgagcg acttttttga
      241 agcttggttt cagaagtttc tcttaccaac attaaccaca ccatcggtta ttatagtaaa
      301 acgaaataag aataggacaa atcgatcagg acagtaaaat cgaattctaa caatgtttta
      361 gaagtccata tgtactattc tagtttcaat ataccataac tgctcctagt caacctgcaa
      421 gtcctgcccc agctccaagc tcagctccga ctcaagatcc tagagtggta gtaagcgctt
      481 cggctagctc aacgagcaca caagctcaag agtaagttga caagtctgaa cttcgtgcct
      541 tgagtcaaga gttagaccaa cgcttgaaag ctttggcaac agtatctgat ccgaaaatcg
      601 atgcaaccaa ggctgtcctc ctagatgctc aaaaagctcc ggaagatagt gccttgacag
      661 agtaaggtct gcatactgca gtagagtctg tgaaggctgc cttggactct ctcaaagatg
      721 tgaaagcaaa tgctagcgac agcaagcctg cacaggacaa gaaggatgca aaacaaggaa
      781 cggaagatag taaggattca gataagatga ctgaaacaaa ctcagttccg gcaggagtga
      841 ttgtggtcag tctacttgcc ctcctaggcg tgattgcctt ctggctgatt cgccgtaaga
      901 aagagtcaga aatccagcaa ttaagcacgg aattgatcaa ggttctagga cagctagatg
      961 cagaaaaagc ggataaaaaa gtccttgcca aagcccaaaa ccttctccaa gaaacccttg
     1021 atttcgtgaa agaagaaaat ggctcagcag agacagaaac taaactagta gaggagctta
     1081 aagcaatcct tgacaaactc aagtaaaaca tgatttatga aatgtcagac ctaaaagaca
     1141 ttttcgttca caaaagcagt gacgagtaat ccttgtcgtt gctttttggc tattttgggg
     1201 gataagatcc gccttgacta gcaaaagaaa agattggtcc aatagtgccc gatacgattt
     1261 tgcgtagcag aaagcttaca aataaaattg aatatagtaa aataggatta gaattattaa
     1321 gaaagttggt tctttattgg aaacgatagt atttttaatc tctgtttttc tagcaggtgt
     1381 tttatccttt ttttctcctt gtatttttcc tcttctgcca gtctatgctg ggattttatt
     1441 ggatgatcaa gaaagtgcaa aaagcttttc tttgtttggg agaaaggttc tctggtcagg
     1501 cttgattcga acactttgct ttatcgctgg tatctctctc attttcttta ttctaggctt
     1561 tggtgctggt tactttggtc atattctcta tgcaaattgg tttcgatatg tcatgggagc
     1621 tattattatc attttgggtc ttcaccagat ggaaattttt catttgaaga aattagaagt
     1681 tcaaaaaagt tttaccttta aaaaatcaga ttctaatcgt tattggtcag cttttttact
     1741 tggtattacc tttagctttg gttggacacc ttgtattggt ccagttttaa gttctgtttt
     1801 agcacttgcg gcttctggag gcaatggtgc ttggcaagga gcgatttata ctctcattta
     1861 cactctgggc atggcccttc ctttcttggt cttggcacta gcttcaggtc tagtcatgcc
     1921 atattttagt aaaatcaagc gtcatatgat gctactaaag aaaattggtg gtttcctcat
     1981 cgttttaatg ggaattttgt tactattagg acaagtaaat gttctagctg gaatttttga
     2041 ataaaggagg acaaatgaaa aaagtaatgt ttgctggctt aagtctcttg tcattagttg
     2101 tattgatggc ctgtggtgag gaagaaacta aaaagactca agcagcacaa cagccaaaac
     2161 aacaaacgac tgtacaacaa atttctgttg gaaaagatgc tccagacttt acattgcaat
     2221 ccatggatga caaagaagtt aagttatctg attttaaggg taaaaaggtt tacttgaagt
     2281 tttgggcttc atggtgtggt ccatgcaaga aaagtatgcc agagttgatg gaactagcgg
     2341 cgaaaccaga tcgtgatttc gaaattctta ctgtcattgc accaggaatt caaggtgaaa
     2401 aaactgttga gcaattccca caatggttcc aggaacaagg atataaggat atcccagttc
     2461 tttatgatac caaagcaacc accttccaag cttatcaaat tcgaagcatt cctacagaat
     2521 atttaattga tagccaagga aagattggaa agattcaatt tggtgctatc agtaatgcgg
     2581 atgcagaagc agcatttaaa gaaatgaact agaatcgata aaatctgatt acaagatgta
     2641 gtcagatttt ggtaacttct aaaactaact tccagtttcc cacaacctag cttttagtat
     2701 gagaaaaacg cgtgacatca gtggaaatcc gtcttagact aacttccact ggttttcttt
     2761 ttcttgatat ataagggttc aaaagcgaaa agactcagaa aaagtgcacg acaaatagcc
     2821 ctaaaacaga gtcgtcttag agtaacttcc agttttggga gagagatgga agttactttg
     2881 agaagttacg gtagtcagat ttttttagaa aaacatttta taaatattca catatctcct
     2941 atatttatgg taaaatagaa ttatcagttt attttggagt caaagatgaa tatatttaga
     3001 acaaagaatg ttagtttaga taaaacagag atgcataggc atttgaagtt atgggatttg
     3061 attttgctgg gtatcggagc catggtaggg acaggcgtct ttacaatcac aggtactgca
     3121 gctgcaacac ttgctggccc agccctagtg atttcaatcg ttatttctgc cttgtgtgtg
     3181 ggattatcag ccctcttttt tgcagaattt gcctcgcgag tacccgctac aggaggtgcc
     3241 tatagttacc tctatgctat cttaggagaa ttccctgcct ggttggctgg ttggttaacc
     3301 atgatggagt tcatgacagc catatcaggc gtagcttcgg gttgggcagc ttattttaaa
     3361 ggcttgctct ctcaatacgg gatagccttt cctcaggctt taaatggtac ctttaatcct
     3421 caagcaggga catttgttga tttattgcct attcttgtct tggtcttggt gacttcgctt
     3481 gttttactaa atgccaaggc agccttacgc tttaattcga ttctagttat tttgaaattt
     3541 tccgctttag ctctctttgt tttagtagga atttggaata ttaagtttga taattggagc
     3601 aattttgctc cttacggttt tggacaaatc tatggagcta gtactggtat tatggctggt
     3661 gcatccttga tgttcttcgg ttttttggga tttgaatcca tctctatggc tgtagatgaa
     3721 gtcaagactc ctcaaaaaaa tattcctaga gggattgtct tatcgctttc tatcgtaacc
     3781 attctctatg ccttggtgac ccttgttttg actggtgtgg ttcactatag tcatttaaat
     3841 gtcgatgatg ccgttgcctt tgcccttcgt agtgttggga ttagttgggc agccaactat
     3901 gtgtcattag tggctatctt gaccttgatt acagtttgta tttcgatgac ctatgcccta
     3961 tcgcgtatga tttacagttt agcacgtgac ggcttagtgc ctgctgcctt taaggaactg
     4021 acgaagacta gcaagatacc aaagaatgct actatcttga caggtctagc ttcagcagta
     4081 gcagcaggaa tgttcccact agccagtatt gcagcctttt taaatatttg taccttagcc
     4141 tacttgatca tgttggctta tggtctgatt cgcttacgga aagaaaaagg aatgcccaaa
     4201 gctggggaat ttaaaacacc attggtacct ctgttaccaa ttttatcgat catcatttgt
     4261 ttatccttca tgttacagta taatatgaat acctggattg ctttcctagt tgcgttgtta
     4321 gtaggaagta ttatttactt cacttatggc tataagcatt ctaccataga agaataaagt
     4381 gaaagtctat tgagttgttg acactcagta gatttttata tgtgaaagaa atttcaaatt
     4441 ttttctaaaa atatcttgac agattaaatt ttcaggagta gaatatttac tagttaatta
     4501 aatggttaag gagttgttca tgaagaaaca aaatttattt ttagtcctgt taagtgtctt
     4561 tcttttgtgc ttgggggctt gtggtcaaaa ggaaagtcag acaggaaagg ggatgaaaat
     4621 tgtgaccagt ttttatccta tctacgctat ggttaaggaa gtatctggtg acttgaatga
     4681 tgttcggatg attcagtcaa gtagtggtat tcactccttt gaaccttcgg caaatgatat
     4741 cgcagccatc tatgatgcag atgtctttgt ttaccattct catacactcg aatcttgggc
     4801 aggaagtctg gatccaaatc taaaaaaatc caaagtgaag gtcttagagg cttctgaggg
     4861 aatgaccttg gaacgtgtcc ctggactaga ggatgtggaa gcaggggatg gagttgatga
     4921 aaaaacgctc tatgaccctc acacatggct agatcctgaa aaagctggag aagaagccca
     4981 aattatcgct gataaacttt cagaggtgga tagggagcat aaagagactt atcaaaaaaa
     5041 tgcgcaagcc tttatcaaaa aagctcagga attgactaag aaattccaac caaaatttga
     5101 aaaagcgact cagaaaacat ttgtaacaca acatacagcc ttttcttatc tagcgaagag
     5161 atttgggctt aatcaacttg gtattgcagg tatctctcct gaacaagaac caagtccacg
     5221 acaactaaca gaaattcagg aatttgttaa gacctataag gttaaaacga tttttacaga
     5281 aagtaacgct tcttcaaaag tagctgaaac tcttgtcaaa tcaacaggtg tgggtcttaa
     5341 aactctgaat cctttagagt cagacccaca aaatgacaag acctatttag aaaatcttga
     5401 agaaaatatg agtattctag cagaagaatt aaagtgagga aagaatgaaa attaataaaa
     5461 aatatctagc aggttcagtg gcagtccttg ccctaagtgt ttgttcctat gagcttggac
     5521 gttaccaagc tggtcaggat aagaaagagt ctaatcgagt tgcttatata gatggtgatc
     5581 aggctggtca aaaggcagaa aacttgacac cagatgaagt cagtaagagg gaggggatca
     5641 acgccgaaca aattgttatc aagattacgg atcaaggtta tgtgacctct catggagacc
     5701 attatcatta ctataatggc aaggttcctt atgatgccat catcagtgaa gagctcctca
     5761 tgaaagatcc gaattatcag ttgaaggatt cagacattgt caatgaaatc aagggtggtt
     5821 atgtcattaa ggtaaacggt aaatactatg tttaccttaa ggatgcagct catgcggata
     5881 atattcggac aaaagaagag attaaacgtc agaagcagga acgcagtcat aatcataact
     5941 caagagcaga taatgctgtt gctgcagcca gagcccaagg acgttataca acggatgatg
     6001 ggtatatctt caatgcatct gatatcattg aggacacggg tgatgcttat atcgttcctc
     6061 acggcgacca ttaccattac attcctaaga atgagttatc agctagcgag ttagctgctg
     6121 cagaagccta ttggaatggg aagcagggat ctcgtccttc ttcaagttct agttataatg
     6181 caaatccagc tcaaccaaga ttgtcagaga accacaatct gactgtcact ccaacttatc
     6241 atcaaaatca aggggaaaac atttcaagcc ttttacgtga attgtatgct aaacccttat
     6301 cagaacgcca tgtggaatct gatggcctt
//
LOCUS       DBEJHE010000057         5744 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC4 isolate 671759
            SAMN38261586-rid24793303.denovo.57, whole genome shotgun sequence.
ACCESSION   DBEJHE010000057 DBEJHE010000000
VERSION     DBEJHE010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261586
            Sequence Read Archive: SRR26833752
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 5744)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5744)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576136.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576136.1
            Genome Coverage       :: 109x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 19:48:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,067
            CDSs (total)                      :: 2,029
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 131
            CDSs (without protein)            :: 131
            Pseudo Genes (ambiguous residues) :: 0 of 131
            Pseudo Genes (frameshifted)       :: 64 of 131
            Pseudo Genes (incomplete)         :: 59 of 131
            Pseudo Genes (internal stop)      :: 46 of 131
            Pseudo Genes (multiple problems)  :: 32 of 131
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5744
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261586-rid24793303.denovo.57"
                     /strain="GPSC4"
                     /isolate="671759"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            40..507
                     /locus_tag="ACL3EZ_001977"
     CDS             40..507
                     /locus_tag="ACL3EZ_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0393491.1"
                     /translation="MIDKVVRNLLLTFFFCKMTKIINFLTNILVKKKKICYNEFKLRN
                     RKQKGVIMWVLGFILFMIFFYSNNSKKIKKLENKIKKLERKEKGNAEMSRLLQEMIGK
                     EPIITGVYIGPDNWEVVDVDEEWVKLRSVDNTGKEKFKLQRIEDIQTVEFDGE"
     gene            517..723
                     /locus_tag="ACL3EZ_001978"
     CDS             517..723
                     /locus_tag="ACL3EZ_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGR0393492.1"
                     /translation="MQLKNRLKELRARDGLNQTDLAKLAGVSRQTISLLERDEYTPSI
                     IIALKISQIFNETVESVFRLEEDE"
     gene            723..920
                     /locus_tag="ACL3EZ_001979"
     CDS             723..920
                     /locus_tag="ACL3EZ_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001046145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0393493.1"
                     /translation="MNKYKVIYYVVVIALLVSVFLLIGMDLSWFNPYQGDQFVWLYFA
                     LIPVIEWIEKKSKNLASEKGE"
     gene            923..1657
                     /locus_tag="ACL3EZ_001980"
     CDS             923..1657
                     /locus_tag="ACL3EZ_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HGR0393494.1"
                     /translation="MKKKRRLLFLMSIVLGGFLGMFVGMFKARVESHEIILDVKALMP
                     WISAICLLIGFISMFLTFNFLKKSRKFHSLYQEEMDDDLNETYYVQMYRNLEFGTIAF
                     NITGVAIPLAIFISLSEVIILHTNPQTFFLSFLLFVVFLVAQKSLFKTIAIVRQFDLE
                     FFATPKDVLNYINSYDEGERQANLEQSFRILFQLHQYVLPALYIFLIIISFLTGEIQL
                     LAFLLVGAIHVYINVMQLPMVKRYFK"
     gene            1669..2310
                     /locus_tag="ACL3EZ_001981"
     CDS             1669..2310
                     /locus_tag="ACL3EZ_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="HGR0393495.1"
                     /translation="MKLLKNLGWILLALLSFLFIYGFIQGLATASLALGASPYAVTLL
                     YVALAGVYVYGIYKWYQKAPVHIEKSGFNRFIWLPALVWFLSLVVQFFLPDDPSVNQQ
                     IATDLTLSQPLFSFFAVVIFAPLTEEIVFRGMLARYLFPKQDNSKRTLIFLLVSSLLF
                     ALIHFPGDVQQFFVYFSLGFSLGLAYISRKGLVYSISLHALNNLVGFLMILML"
     gene            2328..2558
                     /locus_tag="ACL3EZ_001982"
     CDS             2328..2558
                     /locus_tag="ACL3EZ_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000832182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0393496.1"
                     /translation="MKRVILLAVIQAVVLFFIIGALAYAFKGDFFYNYLAVVFAPIAG
                     VLRFGTAYITEIVLPRKAAEIAEKRKAGKNSK"
     gene            2910..4673
                     /gene="aspS"
                     /locus_tag="ACL3EZ_001983"
     CDS             2910..4673
                     /gene="aspS"
                     /locus_tag="ACL3EZ_001983"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA];
                     GO_process: GO:0006418 - tRNA aminoacylation for protein
                     translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HGR0393497.1"
                     /translation="MKRSMYAGRVREEHIGQEITLKGWVGRRRDLGGLIFIDLRDREG
                     IMQLVINPEKVSAEVMATAESLRSEFVIEVTGQVAAREQANDKLPTGAVELNVTALIV
                     LNTAKTTPFEIKDGIEANDDTRLRYRYLDLRRPEMLENLKLRAKVTHSIRNYLDELEF
                     IDVETPFLSKSTPEGARDYLVPSRVNKGHFYALPQSPQITKQLLMNAGFDRYYQIVKC
                     FRDEDLRGDRQPEFTQVDLETSFLTEKEIQDITEGLIARVMKETKGIEVTLPFPRMKY
                     DDAMALYGSDKPDTRFDMLLQDLTEVVKGVDFKVFSEAPAVKAIVVKGAADNYSRKDI
                     DKMTEVAKQYGAKGLAWVKVVDGELNGPVAKFLTGIQEELTTALALEDKDLVLFVADT
                     LEVANATLGALRGRIAKELGLIDNDKFNFLWVVDWPMFEWSEEEGRYMSAHHPFTLPQ
                     EETAHELEGDLAKVRAIAYDIVLNGYELGGGSLRINQKDLQERMFKALGFSTEEANDQ
                     FGFLLEAMDYGFPPHGGLAIGLDRFVMLLAGEENIREVIAFPKNNKATDPMTQAPSTV
                     ALKQLEELSLQVEEDETNKTN"
     gene            4651..5592
                     /locus_tag="ACL3EZ_001984"
     CDS             4651..5592
                     /locus_tag="ACL3EZ_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HGR0393498.1"
                     /translation="MKQTKRIKRWRYYLRRFAYQIKILRVLQSISREKYDEKISASLV
                     YGFLSAVAVNFFFQPGHVYSSGATGLAQIISALSNHWFGFHIPISLSFYAINFPLMVL
                     AWYQIGHKFTVFTFITVSMSSFFIQFVPVATLTEDPIINSLFGGVVMGLGIGFALRNN
                     ISSGGTDIVSLTIRKKTGKNVGSISFLVNGTIMLIAGLTFGWKYALYSMITIFVSSRV
                     TDAVFTKQKRMQAMIVTNHPEKVIEKIHKKLHRGATMIHDAEGTYNHERKAVLITVIT
                     RAEFNEFKQIMTQVDPSSFVSVSENVHILGRFVEIDN"
BASE COUNT         1632 a         1058 c         1264 g         1790 t
ORIGIN      
        1 gaagctgacg tggtttgaag agattttcga agagtattaa tgatagataa agtggtcagg
       61 aacttactcc tgaccttttt cttttgcaaa atgacaaaaa tcataaactt tttgacaaat
      121 atacttgtca aaaagaaaaa gatatgttac aatgaattca agttaagaaa taggaagcag
      181 aaaggagtta taatgtgggt actaggattt atactattta tgattttctt ttattctaat
      241 aattctaaaa aaatcaagaa actagagaat aaaatcaaaa aacttgagcg aaaagagaaa
      301 ggaaacgcag aaatgtcgag attattacaa gaaatgattg gaaaggaacc aattataacg
      361 ggagtgtata ttgggccaga taactgggaa gttgtggatg ttgatgagga atgggtcaaa
      421 ctacgtagtg ttgataatac gggaaaagaa aaattcaagt tgcaacgtat tgaagatatc
      481 caaaccgttg aatttgacgg agagtaggtg tgtaacgtgc aactaaaaaa tcgtctaaaa
      541 gagcttcgag ctcgcgatgg tctcaatcaa accgacctag ccaaactggc aggggtttcc
      601 agacagacca ttagcctact agaacgggat gagtacaccc catccattat cattgccctg
      661 aaaatatctc aaattttcaa cgaaacagtc gaatcggtat ttcgtttgga ggaggacgag
      721 tgatgaacaa gtataaagtg atttattatg tagtggtcat agctttatta gtcagcgtat
      781 ttctactgat tgggatggac ctaagctggt ttaatcccta tcaaggcgac caatttgttt
      841 ggctctactt tgctctcatc ccagtaattg aatggattga aaagaaatcc aaaaatctag
      901 caagtgaaaa aggagaatga atatgaaaaa gaaacgtaga ttgttatttt tgatgtctat
      961 tgtcttgggg gggttcttgg gcatgtttgt agggatgttt aaggcacgtg tcgaatccca
     1021 cgaaattatt ttagatgtaa aagccttgat gccatggata tcagctattt gtttactgat
     1081 aggtttcatt agtatgtttt tgactttcaa tttcttaaag aaaagcagaa aatttcattc
     1141 cttgtatcaa gaggaaatgg atgacgatct gaatgaaacc tattatgtgc aaatgtatcg
     1201 gaatcttgag tttggaacca ttgcttttaa tattacaggt gtagcgattc cattggctat
     1261 ttttatttca ttaagtgagg tgattatatt gcatacaaac cctcaaacat ttttcctttc
     1321 tttcttactc tttgtggtat tcttagtcgc tcaaaaatct ctttttaaaa ccattgcgat
     1381 tgttcgtcag tttgatttgg aatttttcgc tacaccaaag gatgtcttga actatataaa
     1441 ttcttatgat gaaggggagc gtcaggctaa tttggaacag agttttcgaa ttttattcca
     1501 attacaccaa tatgtcttac cagccttata tatttttctt attatcattt ctttcttgac
     1561 aggagagatt cagttactag ctttcttgct tgtaggagcc atccatgttt atatcaatgt
     1621 gatgcagtta cctatggtaa aacgttattt caaataaagg agttatctat gaaattactt
     1681 aaaaaccttg gctggattct tctagccctt ctatcctttt tatttatcta tggctttatt
     1741 caggggctcg cgactgcgtc gcttgcttta ggcgcttcac cctatgctgt tactctactc
     1801 tatgtggcct tggctggagt atatgtgtac ggcatttaca aatggtatca gaaggctcct
     1861 gttcatattg agaagagcgg ctttaaccga tttatttggc ttcctgcctt ggtttggttc
     1921 ttatctctgg tcgttcaatt cttcttgcca gatgatcctt cagtaaatca gcaaatagcg
     1981 acagacttga ccttgtctca accacttttc tcattctttg ctgtggttat ttttgctcct
     2041 ttgacggaag agattgtttt tagagggatg ttagcacgct atctctttcc taagcaggac
     2101 aatagtaaac gaaccctgat ttttcttctg gtatctagtc ttctatttgc cttgattcat
     2161 tttccaggtg atgtgcaaca attttttgtc tattttagcc ttggttttag tttgggcttg
     2221 gcttacatta gcagaaaagg tctggtctac agtatttctc ttcacgcttt gaataattta
     2281 gtcggctttt tgatgattct catgctataa tagagtcagg aggtcacatg aaacgagtaa
     2341 ttttattagc agtgattcag gcagtcgttc tatttttcat cattggagcg ctagcttatg
     2401 ccttcaaagg cgatttcttc tataactatc tagcagttgt ctttgctcct attgcaggtg
     2461 tactgcgttt tgggacggct tacataacgg aaattgtctt gcctcgaaag gcagccgaaa
     2521 tcgctgaaaa gcgtaaagca ggcaaaaatt caaaataaaa gagtccggtg aagttcatcg
     2581 gatttttgta ttatactcaa tgaaaatcaa agagtaaact aggaagctag ccgcaggttg
     2641 ctcaaaacac tgttttgagg ttgtagatga aactgacgaa gtcagctcaa aacatggttt
     2701 tgaggttgta gatgaaactg acgaagtcag taaccatacc tacggtaagg cgacgctgac
     2761 gtggtttgaa gagattttcg aagagtatta gcgctaattt ttagggcttt cacttgactt
     2821 ttaaagactg gcaaactttt ctgatgattt tcatgaagag cctgcgcttt tatggtaaaa
     2881 tagtaacaga ataaaagagg agagaaataa tgaaacgtag tatgtatgct ggtcgtgttc
     2941 gtgaggaaca catcggacaa gaaataacct tgaaaggatg ggttggccgt cgtcgtgacc
     3001 ttggtggttt gatctttatc gatcttcgtg accgtgaagg aatcatgcag ttggttatca
     3061 accctgaaaa agtatctgca gaggttatgg caacagctga aagccttcgt agcgaatttg
     3121 ttattgaggt gactggtcag gtcgctgcgc gtgagcaagc caatgataag ttgccaactg
     3181 gtgcggttga gttaaacgtg acagctctta ttgtgcttaa cacagctaag acaacaccat
     3241 ttgagattaa ggatggcatt gaggcaaatg acgatacacg tttgcgttac cgttaccttg
     3301 accttcgtcg tccagaaatg ttggaaaatc ttaaacttcg tgccaaggtg acccactcta
     3361 tccgcaacta tttggatgag ttggagttta tcgacgtgga gacaccattc ctttctaagt
     3421 caacgcctga aggggcgcgt gattatttag tgccgtctcg tgttaataag gggcattttt
     3481 acgctcttcc tcaaagtcca caaatcacga aacagctctt gatgaatgct ggttttgacc
     3541 gttactacca aatcgttaaa tgtttccgtg acgaggactt gcgtggagac cgccagcctg
     3601 aatttactca ggtcgacttg gaaacgtcct tccttactga gaaagaaatc caagatatta
     3661 cagaaggctt gatcgcgcgc gtgatgaagg aaacaaaagg catcgaagta acgctaccgt
     3721 tccctcgtat gaaatacgat gatgctatgg ctctttacgg ttctgacaag ccagatactc
     3781 gttttgacat gttgcttcag gacttgacag aagtggtcaa aggtgtagac tttaaagtct
     3841 tttcagaagc acctgctgta aaagcgattg tggtcaaagg agctgcggac aactattcac
     3901 gtaaagacat cgacaagatg acggaagtag ccaaacagta tggtgccaaa ggtcttgctt
     3961 gggtcaaggt ggttgatgga gaattaaacg gaccagttgc caagttcttg actggtatcc
     4021 aagaagaatt gacaacagcg cttgctcttg aagataagga cttggttctc tttgtggcgg
     4081 atacgcttga agtggctaat gcaacactgg gtgcccttcg tggacgtatt gctaaagagc
     4141 ttggcttgat tgataatgat aagttcaact tcctttgggt ggttgactgg ccgatgtttg
     4201 aatggtctga agaagaaggc cgctacatga gcgcccacca tccattcaca cttccacagg
     4261 aagagactgc tcacgaatta gaaggtgatt tggctaaggt tcgtgccatt gcttacgata
     4321 tcgtcttgaa cggttatgag cttggtggtg gtagccttcg tatcaaccaa aaagaccttc
     4381 aagaacgcat gttcaaggct cttggtttct caactgaaga agccaatgac cagtttggtt
     4441 tccttcttga agccatggac tatggtttcc caccacacgg tggtttggct atcgggcttg
     4501 accgttttgt catgttgctt gctggagaag aaaatatccg tgaagtcatt gcctttccta
     4561 agaacaacaa ggcaactgac ccaatgacac aagctccatc aacagtcgct ctcaaacaac
     4621 tagaggaact cagcttacaa gtagaagaag atgaaacaaa caaaacgaat taagcggtgg
     4681 cgctattatc tgcgccgctt tgcttatcag ataaaaattt tacgtgtctt acaaagtatc
     4741 tctcgagaaa agtatgatga gaagatttcg gcctctctgg tctatggttt tttatcagca
     4801 gtagcagtta atttcttttt ccaaccaggg catgtgtatt cgagtggtgc aacaggtctg
     4861 gcacagatta tctctgcctt gagtaatcac tggtttggtt ttcatattcc gatttcgcta
     4921 agcttctacg ccattaactt ccctttgatg gtcttagctt ggtatcagat tggccataag
     4981 ttcaccgtct ttacctttat cacggtatct atgagttcct tctttatcca gtttgtccct
     5041 gtggcaacct tgacggagga tcccattatc aattcccttt ttgggggtgt tgttatgggt
     5101 ttggggattg gttttgctct tcgaaacaat atctccagtg gtgggacgga tatcgtcagc
     5161 ctgactattc gcaagaaaac gggtaagaat gtcggtagta tttctttctt ggtaaatgga
     5221 actatcatgc tgatagcagg tttgaccttt ggttggaaat acgctcttta ttctatgatt
     5281 accatctttg tctctagccg tgtgacagac gcagtcttta ctaagcaaaa gcgtatgcag
     5341 gccatgattg tgacaaatca tccagagaag gtaattgaaa aaatccataa aaaattgcac
     5401 cgcggagcaa ccatgatcca cgatgcagaa ggaacctata atcacgagag aaaggcagtt
     5461 ttaatcactg tcattacacg tgcagagttt aatgaattta aacagattat gacacaagtg
     5521 gatccaagct cctttgtctc tgtctcggaa aacgttcata ttctaggaag atttgttgag
     5581 atagataatt agtgattaat actcttcgaa aatctcttca aaccacgtca gcttcacctt
     5641 gccgtatata tgttactgac ttcgtcagtt ctatctgcaa cctcaaaacc atgttttgag
     5701 ctgacttcgt cagttctatc tgcaacctca aaaccatgtt ttga
//
LOCUS       DBEJHE010000058         5661 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC4 isolate 671759
            SAMN38261586-rid24793303.denovo.58, whole genome shotgun sequence.
ACCESSION   DBEJHE010000058 DBEJHE010000000
VERSION     DBEJHE010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261586
            Sequence Read Archive: SRR26833752
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 5661)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5661)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576136.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576136.1
            Genome Coverage       :: 109x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 19:48:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,067
            CDSs (total)                      :: 2,029
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 131
            CDSs (without protein)            :: 131
            Pseudo Genes (ambiguous residues) :: 0 of 131
            Pseudo Genes (frameshifted)       :: 64 of 131
            Pseudo Genes (incomplete)         :: 59 of 131
            Pseudo Genes (internal stop)      :: 46 of 131
            Pseudo Genes (multiple problems)  :: 32 of 131
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5661
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261586-rid24793303.denovo.58"
                     /strain="GPSC4"
                     /isolate="671759"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(<1..2609)
                     /gene="psrP"
                     /locus_tag="ACL3EZ_001985"
     CDS             complement(<1..2609)
                     /gene="psrP"
                     /locus_tag="ACL3EZ_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine-rich repeat glycoprotein adhesin PsrP"
                     /protein_id="HGR0393499.1"
                     /translation="MFFRRQKGEYRETDRVTRFKLIKSGKHWLRASTSLFGLFKVMRG
                     GVDTTQVMTETVEDKVSHSITGLDILKGIVAAGTVISGTVATQTKVFTNESAVLEKTV
                     EKTDALATNGTVVLGTISTSNSASSTSLSASESASTSASESASTSASTSASTSASESA
                     STSASTSISASSTVVGSQTAAATEATAKKVEEDRKKPASDYVASVTNVNLQSYAKRRK
                     RSVDSIEQLLASIKAAVFSGNTIVNGAPAINASLNIAKSETKVYTGKGVDSVYNVPIY
                     YRLTVTNDGLKLTFTYTVTYVDPKTKTLGNISKKMSNGYSIYNTGTSIQTMLTLGSGL
                     GTPSDVKNSITNKNGGQVQYYNTSTMTKRGSRYTWGNGAQMNGWQAKREYGLTSSWTV
                     PITGTDTSFTFTPYAAKTDNIRTNYFNGRGKVVESSTTSQSLSQSKSLSVSASQSASA
                     SASTSASASASTSASASASTSASASTSASASASTSASASASTSASESASTSASASAST
                     SASASASTSASASASTSASASASTSASASASTSASVSASTSASASASTSASASASTSA
                     SESASTSASESASTSASASASTSASASASTSASASASTSASESASTSASASASTSASA
                     SASTSASESASTSASASASTSASESASTSASASASTSASASASTSASASASTSASESA
                     STSASASASTSASASASTSASASASTSASASASTSASVSASTSASESASTSASASAST
                     SASASASTSASASASTSASVSASTSASESASTSASASASTSASASASTSASASASTSA
                     SASASTSASASASTSASASASTSASESASTSASASASISASESASTSASASASTSASA
                     SASTSASASTSASA"
     gene            complement(2853..3314)
                     /locus_tag="ACL3EZ_001986"
     CDS             complement(2853..3314)
                     /locus_tag="ACL3EZ_001986"
                     /inference="COORDINATES: protein motif:HMM:NF013842.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 transposase-related protein"
                     /protein_id="HGR0393500.1"
                     /translation="MGKERREQGNLERKKRVVKKRKIPLEELKAFVEAHPDAFLREIA
                     ARFDCALPSVWAVLKQIKVILKKTTSFREQKPEKVSEFLDILDNLKDLPVLYIDETGI
                     NRYLYRPYAGAPRGEKVYDKISGRRFERTNEVEQKLNGSFLIRYIDSQIRE"
     gene            complement(3281..3424)
                     /locus_tag="ACL3EZ_001987"
     CDS             complement(3281..3424)
                     /locus_tag="ACL3EZ_001987"
                     /inference="COORDINATES: protein motif:HMM:NF013842.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 transposase-related protein"
                     /protein_id="HGR0393501.1"
                     /translation="MAYSTDFKQGALDSIKGGHRHVEAAKVFDVGVRTLFTWEKKDVS
                     KGT"
     gene            3693..4073
                     /locus_tag="ACL3EZ_001988"
     CDS             3693..4073
                     /locus_tag="ACL3EZ_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HGR0393502.1"
                     /translation="MTYLEKWFDFNRRQKEIESLLEETIAQQSEQSLTLKEFYLLYYL
                     DLAEEKSLRQIDLPDKLHLSPSAVSRMVARLEAKNCGLLSRMCCHQDRRSSFICLTND
                     GQKTLASLQKTVEESLEAGLDFLI"
     gene            4172..4393
                     /locus_tag="ACL3EZ_001989"
     CDS             4172..4393
                     /locus_tag="ACL3EZ_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HGR0393503.1"
                     /translation="MIEITYIDASKNERTVTFESYEDFERSQQACLIGVADYYPVQKL
                     TYKGHNLDYHGTYGDIFFYLMKQDLSQYN"
     gene            4410..4724
                     /gene="trxA"
                     /locus_tag="ACL3EZ_001990"
     CDS             4410..4724
                     /gene="trxA"
                     /locus_tag="ACL3EZ_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003004519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015035 - protein-disulfide reductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HGR0393504.1"
                     /translation="MAKAITDATFEQETKDGLVLVDFWATWCGPCRMQGPILDKLSEE
                     LSEDVLKIVKMDVDENPNTARAFGIMSIPTLLFKKDGQVVKQVAGVHTAEQIKAIIAE
                     LS"
     gene            5099..5563
                     /gene="queF"
                     /locus_tag="ACL3EZ_001991"
     CDS             5099..5563
                     /gene="queF"
                     /locus_tag="ACL3EZ_001991"
                     /EC_number="1.7.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001852207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0033739 - preQ1 synthase activity
                     [Evidence IEA];
                     GO_function: GO:0046857 - oxidoreductase activity, acting
                     on other nitrogenous compounds as donors, with NAD or NADP
                     as acceptor [Evidence IEA];
                     GO_process: GO:0008616 - queuosine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preQ(1) synthase"
                     /protein_id="HGR0393505.1"
                     /translation="MQHYETVEAVTFAYGQRHHLEIQITREIAKEQGIRHHILDMSLL
                     GQITAQPDFATIHISYIPDKLCVESKSLKLYLFSYRNHGDFHENCINTIGKDLVNLLD
                     PRYLEVWGKFTPRGGISIDPYYNYGKQGTKYEGLAEQRLFQHDLYPEKIDNR"
BASE COUNT         1586 a         1210 c         1227 g         1638 t
ORIGIN      
        1 gctgaggcac tggttgaggc tgaggcgcta gtacttgctg aggctgacgc actcgttgat
       61 gctgaagctg acgcactcgt tgatgccgat tcagacgctg agatacttgc tgaggctgac
      121 gcactggttg atgctgactc agacgcactc gttgacgctg aagctgacgc actcgttgac
      181 gctgaagccg acgcactcgt tgatgctgag gctgacgcac tggttgatgc tgaggctgag
      241 gcgctagtac ttgctgaagc cgacgcactg gtgcttgctg aagccgatgc acttgttgat
      301 gcggattcag aggcactggt tgacgctgag actgaagcac ttgttgaggc tgaggctgag
      361 gcgctagtac ttgctgaagc cgacgcactg gtgcttgctg aagccgaggc acttgttgat
      421 gcggattcag aggcactggt tgacgctgag actgaagcac tggttgatgc tgaagccgac
      481 gcactggtac ttgctgaagc tgatgcactg gttgatgctg aagctgaagc actcgttgat
      541 gctgaagccg aggcacttgt tgatgctgac tcagacgcac tcgttgacgc tgaagctgac
      601 gcactcgttg aggctgaagc cgaagcactc gttgatgctg aggctgacgc actcgttgat
      661 gcagattcag aagctgatgt gcttgctgag gctgacgcac tcgttgatgc tgactcagac
      721 gcactcgttg acgctgaagc cgaagcactt gttgatgcgg aagctgacgc actggtactt
      781 gctgactctg atgcactggt tgacgctgaa gccgaagcac tcgttgatgc tgaagctgat
      841 gcactagtac ttgctgaggc tgacgcactc gttgatgcag attcagacgc actggttgat
      901 gcagattcag acgctgaggt acttgctgag gctgacgcac tcgttgaggc tgaagctgaa
      961 gcactggtgc ttgctgagac tgatgcgctg gtacttgctg aagctgaggc actggttgat
     1021 gcggaagctg aggcacttgt cgatgctgaa gccgaagcac tcgttgacgc tgaagccgac
     1081 gcactggtgc ttgctgaagc tgaagcactc gttgatgcag attcagacgc tgatgtgctt
     1141 gctgaggctg aagcactggt tgacgctgaa gccgacgcac tggttgaagc cgacgcactg
     1201 gtgcttgctg aagctgaggc gcttgtgctt gctgaggctg aggcactggt tgatgctgag
     1261 gctgaggcgc tttgactagc acttactgag agtgacttag actgtgaaag tgactgactg
     1321 gtcgtgctag attcaactac ctttcctcta ccattgaagt agttagttct aatgttatct
     1381 gttttagcag cgtaaggggt aaatgtaaag gatgtatccg ttccagtaat tggtacagtc
     1441 caagatgatg ttaatccata ttctctctta gcctgccaac cattcatttg ggcaccattt
     1501 ccccaagtat acctactacc ccgcttcgtc attgtagatg tattatagta ttgaacctgt
     1561 ccaccatttt tgttagtaat ggagttcttt acatctgaag gggtaccaag accactgcca
     1621 agggttaaca ttgtttgtat tgaagttcct gtattataga tagaatatcc attactcatc
     1681 ttttttgata tattaccaag agtctttgtt ttaggatcca catacgtaac cgtataggta
     1741 aaggtcagtt ttaagccatc atttgtcact gtcaatcgat agtaaattgg aacattatat
     1801 accgaatcta cacctttacc tgtataaact tttgtctcac ttttagcaat gtttagactt
     1861 gcattaattg caggggcgcc atttacaatc gtattgccag aaaaaacagc agcttttata
     1921 gaagccagca attgctcgat ggaatccact gaacgcttgc gtcgcttagc ataagattgg
     1981 agattgacat ttgtaactga tgctacataa tcactagctg gtttcttacg atcttcttcg
     2041 accttcttag cagttgcttc tgtagcggca gctgtttgtg atcctaccac agtagatgat
     2101 gcagagatac ttgtcgaagc cgatgtactt gctgattctg atgcacttgt actcgctgag
     2161 gtcgaagcgc tggttgaggc tgactcagat gcagatgtac ttgccgactc tgaagctgac
     2221 aaactagttg aactcgctga attacttgta gatatcgtac ctagaactac tgtaccattt
     2281 gttgccaaag catccgtttt ctctacagtt ttttcaagta ctgccgactc atttgtaaat
     2341 accttcgttt gagttgcaac ggttccactt atgacagttc ccgcagcaac tatccccttg
     2401 aggatatcaa gcccagtaat tgaatgactt actttatctt ctaccgtttc ggtcatgacc
     2461 tgagtagtat caacaccacc acgcatgacc ttaaacaagc caaaaagaga agtcgaggcc
     2521 cgtagccaat gcttccctga tttgattaat ttgaaccgag ttactcggtc tgtttctcta
     2581 tattcaccct tctgacgtct aaaaaatatt ttgaaatttc ctttcgagta ttattttcat
     2641 gtatggatat aaataaatta ccatactata attatagaat agggaaccca aaatagcaag
     2701 aaacttgagg tatttttgct aaaaaaaaaa agcattttac tattttgtat atatatatat
     2761 attataagat aagtttttta taaagacacg caaatgagta taaatcagct aatttttggt
     2821 ttacattcct atttttatgc ataattattc tgtcattctc taatttgtga atcaatatat
     2881 ctgattagaa aactaccatt gagtttttgc tccacctcat tagtccgctc aaaacgccgt
     2941 ccgctaatct tgtcatagac tttctcccct ctaggagccc ctgcataagg acgatagagg
     3001 tagcggttga ttcccgtttc gtcaatatat aggactggta aatcttttag gttatccaaa
     3061 atatcaagaa actcagaaac tttctcaggc ttttgttccc taaaactggt cgtctttttt
     3121 aaaatgacct taatctgctt taaaactgcc catacggagg gcaaagcaca atcaaaacgg
     3181 gccgcaattt cccgtaaaaa agcgtctgga tgagcctcta caaaggcttt caattcttct
     3241 aaagggatct tacgcttttt gacgactcgc tttttccgct ctaagttccc ttgctcacgt
     3301 ctttcttttc ccacgtgaag agagttctga cgccgacatc aaaaactttg gccgcctcga
     3361 catgtctgtg ccctcctttg atggaatcta atgctccttg tttaaaatca gtactatatg
     3421 ccatagcttt attagaccat gcttatttta aactaagcaa ctatagatag agaaatgaaa
     3481 taaaatctga attcgaatgt gataaggagt tagaaattga aacaatagga ttcccccatt
     3541 attcacacaa aaataaaacc actaaaaaac agagcttgcc agcattcttg aaaagtagta
     3601 taattattgc atgcgcaatc atcttgtgac gcagagactg cccgttaatg gactttcttc
     3661 tattttatga ctctaaaaag aaaggagaca ctatgaccta tttggaaaaa tggtttgact
     3721 tcaatcggcg tcagaaagaa attgaaagtc tcttggaaga gaccattgcc caacagagcg
     3781 agcaaagtct gaccttgaaa gagttctacc tgctctacta tctggacttg gctgaagaaa
     3841 aatctctacg ccagattgac ctgccagata agcttcatct gagcccgagc gcagtttcta
     3901 ggatggtggc tcgcttggaa gctaaaaatt gcggtctact cagtcgcatg tgttgccatc
     3961 aagatagacg ctctagtttt atctgcctga caaatgatgg gcaaaagaca ctggcctcgc
     4021 tacaaaagac tgtcgaagaa agcttggaag caggtttgga tttcttgatt taagatgatt
     4081 tttaaaaaag ttgcgtgcgc aatcattttt cttgacattc tcttttataa ggagtaaaat
     4141 aaagttagca ttaaacaaag gagttttaaa tatgattgaa attacctata tagatgccag
     4201 caagaacgaa agaactgtga ctttcgagtc ttatgaagac tttgaacgtt cgcaacaagc
     4261 ttgccttatc ggcgtcgcag actactaccc tgtccaaaaa ttaacctaca agggtcataa
     4321 tttggactac catgggactt atggagatat cttcttctat ctcatgaaac aagatttaag
     4381 ccaatataac taaaaaaagg agaaatacaa tggcaaaagc aattacagat gcaacattcg
     4441 aacaagaaac aaaagacggt ttggtcttag tagacttctg ggcaacttgg tgtggtccat
     4501 gtcgtatgca aggtccaatc ttggacaaat tgtctgaaga actttcagaa gatgtcttga
     4561 aaatcgttaa aatggacgtt gatgaaaatc caaacacagc tcgtgctttt ggaatcatgt
     4621 ctattccaac tcttctcttc aaaaaagacg gccaagttgt caaacaagtt gcaggtgttc
     4681 acacagcaga acaaatcaag gccatcattg ctgaattgag ctaatcaaac gagagaccaa
     4741 gtactttctt tggtctcttt tttcttgccc tttgccattt ttcaaaaaat atgctagact
     4801 atagtagatt gaaactagaa tagtacatct ctacttctaa aacattgtta gaaatcgatt
     4861 tgactgtcct gatcgatttg tcctgttctt atttcacttt actatataaa tagaatatta
     4921 cgatatttgg gatatgccat cgctaaaaaa aacctcgatt tggtattttt tagctcccta
     4981 atgggagctt tttacgtgct ctgaacattt cccattttgg aaggagtact atgaaacgtc
     5041 aatcagcctt ggtcgtctta gtggtggtca agattcaaaa acctgccttt tctggaccat
     5101 gcaacactat gaaacagtcg aagctgtcac ctttgcctac ggccaacgtc atcacctcga
     5161 aattcaaatt actagagaaa tcgctaagga acagggcatt cgtcaccata tcctcgatat
     5221 gtctctgctg ggacaaatca ctgctcagcc agactttgcg acgattcata tttcctacat
     5281 tcctgacaag ctctgtgtcg agtcaaaatc cctcaaacta tatctattta gctaccgaaa
     5341 ccacggagat ttccacgaaa actgtatcaa caccatcggg aaagacttgg tcaacttgct
     5401 agaccctcgc tatttagaag tctggggaaa attcactccg cgcggtggca tttcaatcga
     5461 cccctactat aactacggta agcaaggaac taagtatgag ggcttggcag aacaacgcct
     5521 cttccaacac gacctttatc cagagaaaat tgacaaccgc taaagtcata ctcaatgaaa
     5581 atcaaagagc aaactaggaa gttagccgca ggttactcaa agcagtgttt gaggttgtag
     5641 ataaaactga cgaagtcagc t
//
LOCUS       DBEJHE010000059         5147 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC4 isolate 671759
            SAMN38261586-rid24793303.denovo.59, whole genome shotgun sequence.
ACCESSION   DBEJHE010000059 DBEJHE010000000
VERSION     DBEJHE010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261586
            Sequence Read Archive: SRR26833752
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 5147)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5147)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576136.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576136.1
            Genome Coverage       :: 109x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 19:48:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,067
            CDSs (total)                      :: 2,029
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 131
            CDSs (without protein)            :: 131
            Pseudo Genes (ambiguous residues) :: 0 of 131
            Pseudo Genes (frameshifted)       :: 64 of 131
            Pseudo Genes (incomplete)         :: 59 of 131
            Pseudo Genes (internal stop)      :: 46 of 131
            Pseudo Genes (multiple problems)  :: 32 of 131
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5147
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261586-rid24793303.denovo.59"
                     /strain="GPSC4"
                     /isolate="671759"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            280..1825
                     /locus_tag="ACL3EZ_001992"
     rRNA            280..1825
                     /locus_tag="ACL3EZ_001992"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            1877..1949
                     /locus_tag="ACL3EZ_001993"
     tRNA            1877..1949
                     /locus_tag="ACL3EZ_001993"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1910..1912,aa:Ala,seq:tgc)
     gene            2074..4975
                     /locus_tag="ACL3EZ_001994"
     rRNA            2074..4975
                     /locus_tag="ACL3EZ_001994"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
     gene            5052..>5147
                     /gene="rrf"
                     /locus_tag="ACL3EZ_001995"
     rRNA            5052..>5147
                     /gene="rrf"
                     /locus_tag="ACL3EZ_001995"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT         1457 a         1042 c         1508 g         1140 t
ORIGIN      
        1 acacgggttc gaatcccgta cggactatgg tatgttgcgt caggagcact tgatgaaaaa
       61 aagtttaaaa aagcttaaaa atcttcaaaa aagtgttgac aagtgaaagt ggctgtgata
      121 tactaatata gttgtcgctt gagagaagca agtgacaaag acctttgaaa actgaacaag
      181 acgaaccaat gtgcagggcg ctacaacgta agttgtagta ctgaacaatg aaaaaaacaa
      241 taaatctgtc agtgacagaa atgagtgaga actcaaactt ttaatgagag tttgatcctg
      301 gctcaggacg aacgctggcg gcgtgcctaa tacatgcaag tagaacgctg aaggaggagc
      361 ttgcttctct ggatgagttg cgaacgggtg agtaacgcgt aggtaacctg cctggtagcg
      421 ggggataact attggaaacg atagctaata ccgcataaga gtggatgttg catgacattt
      481 gcttaaaagg tgcacttgca tcactaccag atggacctgc gttgtattag ctagttggtg
      541 gggtaacggc tcaccaaggc gacgatacat agccgacctg agagggtgat cggccacact
      601 gggactgaga cacggcccag actcctacgg gaggcagcag tagggaatct tcggcaatgg
      661 acggaagtct gaccgagcaa cgccgcgtga gtgaagaagg ttttcggatc gtaaagctct
      721 gttgtaagag aagaacgagt gtgagagtgg aaagttcaca ctgtgacggt atcttaccag
      781 aaagggacgg ctaactacgt gccagcagcc gcggtaatac gtaggtcccg agcgttgtcc
      841 ggatttattg ggcgtaaagc gagcgcaggc ggttagataa gtctgaagtt aaaggctgtg
      901 gcttaaccat agtaggcttt ggaaactgtt taacttgagt gcaagagggg agagtggaat
      961 tccatgtgta gcggtgaaat gcgtagatat atggaggaac accggtggcg aaagcggctc
     1021 tctggcttgt aactgacgct gaggctcgaa agcgtgggga gcaaacagga ttagataccc
     1081 tggtagtcca cgctgtaaac gatgagtgct aggtgttaga ccctttccgg ggtttagtgc
     1141 cgtagctaac gcattaagca ctccgcctgg ggagtacgac cgcaaggttg aaactcaaag
     1201 gaattgacgg gggcccgcac aagcggtgga gcatgtggtt taattcgaag caacgcgaag
     1261 aaccttacca ggtcttgaca tccctctgac cgctctagag atagagtttt ccttcgggac
     1321 agaggtgaca ggtggtgcat ggttgtcgtc agctcgtgtc gtgagatgtt gggttaagtc
     1381 ccgcaacgag cgcaacccct attgttagtt gccatcattt agttgggcac tctagcgaga
     1441 ctgccggtaa taaaccggag gaaggtgggg atgacgtcaa atcatcatgc cccttatgac
     1501 ctgggctaca cacgtgctac aatggctggt acaacgagtc gcaagccggt gacggcaagc
     1561 taatctctta aagccagtct cagttcggat tgtaggctgc aactcgccta catgaagtcg
     1621 gaatcgctag taatcgcgga tcagcacgcc gcggtgaata cgttcccggg ccttgtacac
     1681 accgcccgtc acaccacgag agtttgtaac acccgaagtc ggtgaggtaa ccgtaaggag
     1741 ccagccgcct aaggtgggat agatgattgg ggtgaagtcg taacaaggta gccgtatcgg
     1801 aaggtgcggc tggatcacct cctttctaag gataaggaac tgcgcattgg tcttgtttag
     1861 tcttgagagg tcttgtgggg ccttagctca gctgggagag cgcctgcttt gcacgcagga
     1921 ggtcagcggt tcgatcccgc taggctccat tggtgagaga tcaccaagta atgcacattg
     1981 aaaattgaat atctatatca aatagtaaca agaaaataaa ccgaaaacgc tgtagtatta
     2041 ataagagttt atgactgaaa ggtcagaaaa taaggttaag ttaataaggg cgcacggtgg
     2101 atgccttggc actaggagcc gacgaaggac gtgacaaacg acgatatgcc ttgggtagct
     2161 gtaagtaagc gatgatccag ggatttccga atgggggaac ccaacaggta atacctgtta
     2221 cccacatctg ttaaggatgt gaggaggaag acgcagtgaa ctgaaacatc taagtagctg
     2281 caggaagaga aagcaaaagc gattgcctta gtagcggcga gcgaaacggc agaagggcaa
     2341 accgaagagt ttactcttcg gggttgtagg actgcaatgt ggactcaaag attatagaag
     2401 aatgatttgg gaagatcagc caaagagagt aatagcctcg tatttaaaat agtctttgta
     2461 cctagcagta tcctgagtac ggcgggacac gtgaaatccc gtcggaatct gggaggacca
     2521 tctcccaacc ctaaatactc cctagtgacc gatagtgaac cagtaccgtg agggaaaggt
     2581 gaaaagcacc ccgggagggg agtgaaatag aacctgaaac cgtgtgccta caacaagttc
     2641 gagcccgtta atgggtgaga gcgtgccttt tgtagaatga accggcgagt tacgttatga
     2701 tgcgaggtta agttgaagag acggagccgt agggaaaccg agtctgaata gggcgcctta
     2761 gtatcatgac gtagacccga aaccatgtga cctacccatg agcaggttga aggtgcggta
     2821 agacgcactg gaggaccgaa ccagggcacg ttgaaaagtg cttggatgac ttgtgggtag
     2881 cggagaaatt ccaaacgaac ttggagatag ctggttctct ccgaaatagc tttagggcta
     2941 gcgtcgacat tagagattct tggaggtaga gcactgtttg ggtgaggggt ccatcccgga
     3001 ttaccaatct cagataaact ccgaatgcca atgaattatg gtcggcagtc agactgcgag
     3061 tgctaagatc cgtagtcgaa agggaaacag cccagaccac cagctaaggt cccaaaataa
     3121 ttgttaagtg gaaaaggatg tggggttgca cagacaacta ggatgttagc ttagaagcag
     3181 ctattcattc aaagagtgcg taatagctca ctagtcgagt gaccctgcgc cgaaaatgta
     3241 ccggggctaa aacaatttac cgaagctgtg gataccttta taggtatggt aggagagcgt
     3301 tctatgtgtg atgaaggtat accgtgagga gtgctggaac gcatagaagt gagaatgccg
     3361 gtatgagtag cgaaagacag gtgagaatcc tgtccaccgt aagactaagg tttccagggg
     3421 aaggctcgtc cgccctgggt tagtcgggac ctaaggagag accgaaaggt gtatccgatg
     3481 gacaacaggt tgatattcct gtactagagt atgtagtgat ggagggacgc agtaggctaa
     3541 ctaaagcaga cgattggaag agtctgtcta agcagtgagg tgtgaattga gtcaaatgct
     3601 taattctata acattgagct gtgatgggga gcgaagttta gtagcgaagt tagtgacgtc
     3661 acactgccaa gaaaagcttc tagcgtttaa acatactcta cccgtaccgc aaaccgacac
     3721 aggtagtcga ggcgagtagc ctcaggtgag cgagagaact ctcgttaagg aactcggcaa
     3781 aatgaccccg taacttcggg agaaggggtg ctgacttaaa gtcagccgca gtgaataggc
     3841 ccaagcaact gtttatcaaa aacacagctc tctgctaaat cgtaagatga tgtatagggg
     3901 gtgacgcctg cccggtgctg gaaggttaag aggagtgctt agcgtaagcg aaggtatgaa
     3961 ttgaagcccc agtaaacggc ggccgtaact ataacggtcc taaggtagcg aaattccttg
     4021 tcgggtaagt tccgacccgc acgaaaggcg taatgatttg ggcactgtct caacgagaga
     4081 ctcggtgaaa ttttagtacc tgtgaagatg caggttaccc gcgacaggac ggaaagaccc
     4141 catggagctt tactgcagtt tgatattgag tgtctgtacc acatgtacag gataggtagg
     4201 agtctaagag atcgggacgc cagtttcgaa ggagacgctg ttgggatact acccttgtgt
     4261 tatggccact ctaacccaga taggtgatcc ctatcggaga cagtgtctga cgggcagttt
     4321 gactggggcg gtcgcctcct aaaaggtaac ggaggcgccc aaaggttccc tcagaatggt
     4381 tggaaatcat tcgcagagtg taaaggtata agggagcttg actgcgagag ctacaactcg
     4441 agcagggacg aaagtcgggc ttagtgatcc ggtggttccg tatggaaggg ccatcgctca
     4501 acggataaaa gctaccctgg ggataacagg cttatctccc ccaagagttc acatcgacgg
     4561 ggaggtttgg cacctcgatg tcggctcgtc gcatcctggg gctgtagtcg gtcccaaggg
     4621 ttgggctgtt cgcccattaa agcggcacgc gagctgggtt cagaacgtcg tgagacagtt
     4681 cggtccctat ccgtcgcggg cgtaggaaat ttgagaggat ctgctcctag tacgagagga
     4741 ccagagtgga cttaccgctg gtgtaccagt tgtcttgcca aaggcatcgc tgggtagcta
     4801 tgtagggaag ggataaacgc tgaaagcatc taagtgtgaa acccacctca agatgagatt
     4861 tcccatgatt atatatcagt aagagccctg agagatgatc aggtagatag gttagaagtg
     4921 gaagtgtggc gacacatgta gcggactaat actaatagct cgaggactta tccaaagtaa
     4981 ctgagaatat gaaagcgaac ggttttctta agttgaatag atattcaatt ttgagtaggt
     5041 attactcaga gttaagtgac gatagcctag gagatacacc tgtacccatg ccgaacacag
     5101 aagttaagcc ctagaacgcc ggaagtagtt gggggttgcc ccctgtg
//
LOCUS       DBEJHE010000060         4809 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC4 isolate 671759
            SAMN38261586-rid24793303.denovo.60, whole genome shotgun sequence.
ACCESSION   DBEJHE010000060 DBEJHE010000000
VERSION     DBEJHE010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261586
            Sequence Read Archive: SRR26833752
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 4809)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4809)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576136.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576136.1
            Genome Coverage       :: 109x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 19:48:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,067
            CDSs (total)                      :: 2,029
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 131
            CDSs (without protein)            :: 131
            Pseudo Genes (ambiguous residues) :: 0 of 131
            Pseudo Genes (frameshifted)       :: 64 of 131
            Pseudo Genes (incomplete)         :: 59 of 131
            Pseudo Genes (internal stop)      :: 46 of 131
            Pseudo Genes (multiple problems)  :: 32 of 131
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4809
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261586-rid24793303.denovo.60"
                     /strain="GPSC4"
                     /isolate="671759"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            434..886
                     /locus_tag="ACL3EZ_001996"
     CDS             434..886
                     /locus_tag="ACL3EZ_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HGR0393506.1"
                     /translation="MIITKISRLGTYVGVNPHFATLIDFLEKTGLENLTEGSIAIDGN
                     RLFGNCFTYLADGQAGAFFETHQKYLDIHLVLENEEAMAVTSPENVSVTQEYDEEKDI
                     ELYTGKVEQLVHLRAGECLITFPEDLHQPKVRINDEPVKKVVFKVAIS"
     gene            905..2242
                     /locus_tag="ACL3EZ_001997"
     CDS             905..2242
                     /locus_tag="ACL3EZ_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGR0393507.1"
                     /translation="MKKMRKFLCLAGIALAAVALVACSGKKEATTSTEPPTELSGEIT
                     MWHSFTQGPRLESIQKSADAFMQKHPKTKIKIETFSWNDFYTKWTTGLANGNVPDIST
                     ALPNQVMEMVNSDALVPLNDSIKRIGQDKFNETALNEAKIGDDYYSVPLYSHAQVMWV
                     RTDLLKEHNIEVPKTWDQLYEASKKLKEAGVYGLSVPFGTNDLMATRFLNFYVRSGGG
                     SLLTKDLKADLTSQLAQDGIKYWVKLYKEISPQDSLNFNVLQQATLFYQGKTAFDFNS
                     GFHIGGINANSPQLIDSIDAYPIPKIKESDKDQGIETSNIPMVVWKNSKHPEVAKAFL
                     EALYNEEDYVKFLDSTPVGMLPTIKGISDSAAYKENETRKKFKHAEEVITEAVKKGTA
                     IGYENGPSVQAGMLTNQHIIEQMFQDIITNGTDPMKAAKEAEKQLNDLFEAVQ"
     gene            2321..3205
                     /locus_tag="ACL3EZ_001998"
     CDS             2321..3205
                     /locus_tag="ACL3EZ_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGR0393508.1"
                     /translation="MVKERNLTRWIFVLPAMIIVGLLFVYPFFSSIFYSFTNKHLIMP
                     NYKFVGLANYKAVLSDPNFFNAFFNSIKWTVFSLVGQVLVGFVLALALHRVRHFKKLY
                     RTLLIVPWAFPTIVIAFSWQWILNGVYGYLPNLIVKLGLMEHTPAFLTDSTWAFLCLV
                     FINIWFGAPMIMVNVLSALQTVPEEQFEAAKIDGASSWQVFKFIVFPHIKVVVGLLVV
                     LRTVWIFNNFDIIYLITGGGPANATTTLPIFAYNLGWGTKLLGRASAVTVLLFIFLVA
                     ICFIYFAIISKWEKEGRK"
     gene            3205..4038
                     /locus_tag="ACL3EZ_001999"
     CDS             3205..4038
                     /locus_tag="ACL3EZ_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGR0393509.1"
                     /translation="MKKKSSIYLDILSHVLLVGATIVAVFPLVWIIISSVKGKGELTQ
                     YPTRFWPEQFTLDYFTHVINDLHFIDNIRNSLIIALATTLIAIIISAMAAYGIVRFFP
                     KLGAIMSRLLVITYIFPPILLAIPYSIAIAKVGLTNSLFGLMMVYLSFSVPYAVWLLV
                     GFFQTVPIGIEEAARIDGANKFVTFYKVVLPIVAPGIVATAIYTFINAWNEFLYALIL
                     INNTGKMTVAVALRSLNGSEILDWGDMMAASVIVVLPSIIFFSIIQNKIASGLSEGSV
                     K"
     gene            4056..>4809
                     /gene="nanB"
                     /locus_tag="ACL3EZ_002000"
     CDS             4056..>4809
                     /gene="nanB"
                     /locus_tag="ACL3EZ_002000"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="neuraminidase NanB"
                     /protein_id="HGR0393510.1"
                     /translation="MNKRGLYSKLGISVVGISLLMGVPTLIHANELNYGQLSISPIFQ
                     GGSYQLNNKSIDISSLLLDKLSGESQTVVMKFKADEPNSLQALFGLSNSKADFKNNYF
                     SIFMRDSGEIGVEIRDAQKGINYLFSRPASLWGKHKGQAVENTLVFVSDSKDKTYTMY
                     VNGIEVFSETVDTFLPISNINGIDKATLGAVNREGKEHYLAKGSIDEISLFNKAISDQ
                     EVSTIPLSNPFQLIFQSGDSTQANYFRIPTLYT"
BASE COUNT         1578 a          771 c          942 g         1518 t
ORIGIN      
        1 ttagaaaaac gaagtgagca gcttataaat tcaagtcccc aaatagattc atactagtat
       61 cttttgcaaa aaataaaggg cgacttcctt catgaatatc aatttcatct ataaggaagg
      121 tagctaattg aactaactta tttattctgt ttatcgctag aaaaatcaga cctccttgtg
      181 aagattgagg agatacttaa tgaaaatcaa agaagaaact agcaagctag tagcagattg
      241 cccaaaacac cgctttgagg ttgtagataa gactgacgta tataatccaa ggtgaagcga
      301 ctgtggtttg aagagatttt caaagagtat aggctagaga gtagtgtttt tatgtccttc
      361 tagtagaaaa tgctagacag aagaatgggg aacttggata ggaaaaatag attgagaaag
      421 gaggttagaa gagatgatta ttacaaaaat tagccgttta ggaacttatg tgggagtaaa
      481 tccacatttt gcaacattaa tagattttct agaaaaaaca ggactagaaa atttaacaga
      541 aggttcgatt gctatcgatg gtaatcgatt gtttgggaat tgctttactt atctagcaga
      601 tggtcaagca ggggctttct ttgaaacaca ccaaaaatat ttggatattc atttagtttt
      661 ggaaaacgaa gaagccatgg ctgttacatc gccggaaaat gtaagcgtta cccaagaata
      721 tgatgaagag aaagatattg aattatacac agggaaagtg gaacagttgg ttcatttgag
      781 agctggcgaa tgcctcatca cttttccaga agatttacat caacccaagg ttcgtataaa
      841 tgatgaacct gtgaaaaaag ttgtctttaa agttgcgatt tcttaatgta gaaagagaag
      901 aacgatgaaa aaaatgagaa agtttttatg tctagctgga attgcgctag cggctgttgc
      961 cttggtagct tgttcaggaa aaaaagaagc tacaactagt actgaaccac caacagaatt
     1021 atctggtgag attacaatgt ggcactcctt tactcaagga ccccgtttag aaagtattca
     1081 aaaatcagca gatgctttca tgcaaaagca tccaaaaacg aaaatcaaga ttgaaacatt
     1141 ttcttggaat gacttctata ctaaatggac tacaggttta gcaaatggaa atgtgccaga
     1201 tatcagtaca gctcttccta accaagtaat ggaaatggtc aactcagatg ctttggttcc
     1261 gctaaatgat tctatcaagc gtattggaca agataaattt aacgaaactg ccttaaatga
     1321 agcaaaaatc ggagatgatt actactctgt tcctctttat tcacatgcac aagtcatgtg
     1381 ggttagaaca gatttgttaa aagaacataa tattgaggtt cctaaaactt gggatcaact
     1441 ctatgaagct tctaaaaaat tgaaagaagc tggagtttat ggcttgtctg ttccgtttgg
     1501 aacaaatgac ttaatggcaa cacgtttctt gaacttctac gtacgtagtg gtggaggaag
     1561 cctcttaaca aaagatctta aagcagactt gacaagccaa cttgctcaag atggtattaa
     1621 atactgggtt aaattgtata aagaaatctc acctcaagat tctttgaact ttaatgtcct
     1681 tcaacaagct accttgttct atcaaggaaa aacagcattt gactttaact ctggcttcca
     1741 tatcggagga attaatgcca acagtcctca attgattgat tcgattgatg cttatcctat
     1801 tccaaaaatc aaagagtctg ataaagacca aggaattgaa acctcaaaca ttccaatggt
     1861 tgtttggaaa aattcaaaac atccagaagt tgctaaagca ttcttagaag cactttataa
     1921 tgaagaagac tacgttaaat tccttgattc aactccagta ggtatgttgc caactattaa
     1981 ggggattagc gattctgcag cctataaaga aaatgaaact cgtaagaagt ttaaacatgc
     2041 tgaagaagta attactgaag ctgttaaaaa aggtactgct attggttatg aaaatggacc
     2101 aagtgtacaa gctggtatgt tgactaacca acacattatt gaacaaatgt tccaagatat
     2161 cattacaaat ggaacagatc ctatgaaagc agcaaaagaa gcagaaaaac aattaaacga
     2221 tttatttgag gctgttcagt agatgtaaaa gactagaaaa taggtgggct agtgagctga
     2281 aaagctctag cccaatcttg taaaagaagg gagaaggaga atggttaaag aacgtaattt
     2341 aactcgctgg atatttgttt tgccagctat gattatcgta ggattactct ttgtttatcc
     2401 gtttttctcg agtatttttt atagctttac caataagcat ttgattatgc ctaattataa
     2461 atttgttggt ttggctaact ataaagctgt gctatcagat cccaacttct ttaatgcgtt
     2521 ctttaattca attaagtgga ccgttttctc attagttggt caagttttag tagggtttgt
     2581 attggcttta gctcttcaca gagtacgcca cttcaagaaa ttatatagga ccttattgat
     2641 tgttccttgg gcatttccta ccatcgtcat tgccttttct tggcagtgga ttctaaacgg
     2701 ggtttatggc tacttaccta atctaatcgt aaaattaggt ttaatggaac atacacctgc
     2761 atttttgaca gatagtacat gggcattcct atgtttggtg tttatcaaca tttggtttgg
     2821 agcaccaatg attatggtta atgtgctttc agctttgcaa acagtaccag aagaacaatt
     2881 tgaggctgct aagatagatg gtgcttcaag ttggcaggtg ttcaagttta tcgtctttcc
     2941 acatattaaa gtggttgtag gacttctagt tgttttgaga actgtatgga tctttaataa
     3001 ctttgacatt atctacctca ttactggtgg tggaccagcc aatgctacaa cgacgcttcc
     3061 aatttttgct tacaacctgg gctggggaac taaattgttg ggtcgtgctt cagcagttac
     3121 agtattgctc tttatcttct tggtggcgat ttgctttatc tactttgcta tcatcagtaa
     3181 gtgggaaaag gagggtagaa aataatgaag aagaaatcca gtatttattt agatattctc
     3241 tcacatgtac ttttagttgg tgcgaccatc gttgcagttt tcccattggt atggattatc
     3301 atatcttctg tcaaagggaa aggggaatta actcagtatc caacacgatt ttggcctgaa
     3361 cagtttacat tagattattt cactcatgtt atcaacgatt tgcacttcat tgataacatt
     3421 cgaaacagtt taatcattgc cttggctaca acccttattg cgattattat ttctgctatg
     3481 gcagcctatg gtattgttcg attctttcct aaattgggag caatcatgtc gagactactc
     3541 gtcattacct acattttccc accaattttg ttagcaattc cctattcaat tgccattgct
     3601 aaagttgggt taacaaatag tttatttggc ttgatgatgg tttatctatc ttttagtgtt
     3661 ccatatgcag tttggctctt agttggattt ttccaaacag ttccaattgg aattgaagaa
     3721 gcggctagaa ttgatggtgc aaataaattt gttacgtttt ataaagttgt gctaccgatt
     3781 gtagcaccag gtattgtagc aacagctatt tatacattta tcaatgcttg gaatgaattc
     3841 ctgtatgcct tgattttgat taacaataca ggaaagatga cagtagcagt agcccttcgt
     3901 tcacttaatg gttcagaaat actagactgg ggagatatga tggcagcgtc tgttattgta
     3961 gttcttccat caattatttt cttctctatc atccaaaata agattgcaag tggattatca
     4021 gaaggatctg tgaagtagac gaaagaagga aaaaaatgaa taaaagaggt ctttattcaa
     4081 aactaggaat ttctgttgta ggcattagtc ttttaatggg agttcccact ttgattcatg
     4141 cgaatgaatt aaactatggt caactgtcca tatctcctat ttttcaagga ggttcatatc
     4201 aactgaacaa taagagtata gatatcagct ctttgttatt agataaattg tctggagaga
     4261 gtcagacagt agtaatgaaa tttaaagcag atgaaccaaa ctctcttcaa gctttgtttg
     4321 gcctatctaa tagtaaagca gactttaaaa ataattactt ttcaattttc atgagagatt
     4381 ctggtgagat aggtgtagaa ataagagacg cccaaaaggg aataaattat ttattttcca
     4441 gaccagcttc attatgggga aaacataaag gacaggcagt tgaaaataca ctagtatttg
     4501 tatctgattc taaagataaa acatacacaa tgtatgttaa tggaatagaa gtgttctctg
     4561 aaacagttga tacatttttg ccaatttcaa atataaatgg tatagataag gcaacactag
     4621 gagctgttaa tcgtgaaggt aaggaacatt acctcgcaaa aggaagtatt gatgaaatca
     4681 gtctatttaa caaagcaatt agtgatcagg aagtttcaac tattcccttg tcaaatccat
     4741 ttcagttaat tttccaatca ggagattcta ctcaagctaa ctattttaga ataccgacac
     4801 tatatacat
//
LOCUS       DBEJHE010000061         4485 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC4 isolate 671759
            SAMN38261586-rid24793303.denovo.61, whole genome shotgun sequence.
ACCESSION   DBEJHE010000061 DBEJHE010000000
VERSION     DBEJHE010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261586
            Sequence Read Archive: SRR26833752
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 4485)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4485)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576136.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576136.1
            Genome Coverage       :: 109x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 19:48:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,067
            CDSs (total)                      :: 2,029
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 131
            CDSs (without protein)            :: 131
            Pseudo Genes (ambiguous residues) :: 0 of 131
            Pseudo Genes (frameshifted)       :: 64 of 131
            Pseudo Genes (incomplete)         :: 59 of 131
            Pseudo Genes (internal stop)      :: 46 of 131
            Pseudo Genes (multiple problems)  :: 32 of 131
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4485
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261586-rid24793303.denovo.61"
                     /strain="GPSC4"
                     /isolate="671759"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(55..962)
                     /locus_tag="ACL3EZ_002001"
                     /pseudo
     CDS             complement(55..962)
                     /locus_tag="ACL3EZ_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000603324.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
     gene            1218..3851
                     /gene="polA"
                     /locus_tag="ACL3EZ_002002"
     CDS             1218..3851
                     /gene="polA"
                     /locus_tag="ACL3EZ_002002"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014932012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006261 - DNA-templated DNA replication
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HGR0393511.1"
                     /translation="MDKKKLLLIDGSSVAFRAFFALYQQLDRFKNAAGLHTNAIYGFQ
                     LMLSHLLERVEPSHILVAFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDH
                     MGIRHYELAQYEADDIIGTLDKLAEQDGFDITIVSGDKDLIQLTDEHTVVEISKKGVA
                     EFEAFTPDYLMEEMGLTPAQFIDLKALMGDKSDNIPGVTKVGEKTGIKLLLEYGSLEG
                     IYENIDGMKTSKMKENLINDKEQAFLSKTLATIDTKAPIAIGLEDLVYSGPDVENLGK
                     FYDEMGFKQLKQALNVSSADVAKGLDFTIVDQISQDMLSEESIFHFELFGENYHTDNL
                     VGFAWSCEDKLYATDKLELLQDPIFKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAF
                     DIRLAKYLLSTVEDNEIATIASLYGQTYLVDDETFYGKGVKKAIPEREKFLEHLACKL
                     AVLVETEPILLEKLSENGQLELLYDMEQPLAFVLAKMEIAGIVVKKETLLEMQAENEL
                     VIEKLTQEIYELAGEEFNVNSPKQLGVLLFEKLGLPLEYTKKTKTGYSTAVDVLERLA
                     PIAPIVKKILDYRQIAKIQSTYVIGLQDWILADGKIHTRYMQDLTQTGRLSSVDPNLQ
                     NIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIELRVLAHISKDEHLIKAFQEGADIH
                     TSTAMRVFGIERPDNVTANDRRNAKAVNFGVVYGISDFGLSNNLGISRKEAKAYIDTY
                     FERFPDIKNYMDEVVREARDKGYVETLFKRRRELPDINSRNFNIRGFAERTAINSPIQ
                     GSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVPKSELVEMKKLVKQTMEEA
                     IQLSVPLIADENEGATWYEAK"
     gene            3936..4373
                     /locus_tag="ACL3EZ_002003"
     CDS             3936..4373
                     /locus_tag="ACL3EZ_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0120225 - coenzyme A binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HGR0393512.1"
                     /translation="MSQEFINPSDGVIRQYLATSKTLAVVGLSDREETTSNRVTKEMQ
                     ARGYKIIPVNPKAAGGEILGEKAYASLAEIPFPVDIVNVYRRSEFLPDVARDFLKADA
                     KIFWAQLGLESLEAKEILRDGGCDDIVMNRCIKREHTRLIEEA"
BASE COUNT         1221 a          833 c         1079 g         1352 t
ORIGIN      
        1 aggctccata atatccatag gggatttacc cactatggat attatggagc cattttacaa
       61 cagtgcctca aattcagata ctgacatacc taattgctgg ctggcaacct cagaagtcag
      121 aagaccttgg cgtactatgt ctaggaaggc aaaaagtttc ctttctgccc ttccttcaac
      181 tttcccacgc tctagtcctt gttcaaggcc ttcagcccta gcagtttcca aggcatagtc
      241 ctgtgctaac aagacttgtt cttctcgcat atgtagttga ctaaacattt tcctgtcctc
      301 ctcggaccag ctcttgtagt ccagcagttg atttgcttgg ctaatggctc gttgcggttg
      361 ctgggtaaag ggcttgttgc cgaaaaactc caaccatggc ttgcgaacct tgtctttgct
      421 ggtttctctg tattttttaa ttccaagaat gccatcttaa ccagatggtt ttcctgtcca
      481 ttgttggtaa tcgccaatac ctcacctgtt gtgtcttcgc gcatactaaa gctatgaaaa
      541 gccaggtcat ctgagaaata attactatcc acgatagcaa tggcgtaaac aggagcgatg
      601 tgtttgtagc tctagtgagt atcaccttct cgctgacgaa ttttttcaag attttgatta
      661 acctgactgc acaggtaagt ccacaagtga ttgatgaaaa aattctgatg atggacttga
      721 atctcaataa ttacttgagt accgttatcc aactccgcca agacgtctat actggtataa
      781 aaatcctgca ccgagtaagg catggagagt aatacgtgaa tatcgcttcc ctccaaaatg
      841 gtcacatttt ttgctggcaa gtccagcata tcgcgaataa attgacaagt gatttctgga
      901 ttgctgaata ttttcttagc aatcaaatca ttagttgggc tgatgcccgg atgtctgaga
      961 atcctcctat tcctccttct atagtgagtt gaaataagat gtgaataact ctatcaggaa
     1021 agtcaaatta atttatagaa atattttagc agtcaaggtg tactattata gattcaatat
     1081 attatattat agcacatttt taaatctagg tttactaaat tctctggctc tatctattta
     1141 ttcggaaaaa gtttgaaaaa tacttgctct agctcttccc aatggtattt tttgattctt
     1201 tcctttataa tgggtgtatg gataagaaaa aattattatt gattgatggg tcttctgtag
     1261 cttttcgggc gttttttgcg ctgtatcagc agttggaccg ttttaagaat gcggctggtt
     1321 tgcataccaa tgcgatttat ggttttcagt tgatgttgag tcatttgttg gagcgggttg
     1381 agccgagtca tattttggtg gcttttgatg cgggaaagac gaccttccgg acagagatgt
     1441 atgcggacta taagggtggt cgggccaaga ctcctgatga gtttcgtgag caatttcctt
     1501 tcattcgtga gttgctggat catatgggga ttcgtcacta tgagctggct cagtatgagg
     1561 cggatgacat cattgggacg ctggataagc tagcagagca ggatggtttt gatattacca
     1621 ttgtcagtgg ggacaaggat ttgattcagc tgacggatga gcatacggtg gttgaaattt
     1681 ccaagaaagg tgtggctgag tttgaggcct ttacgccaga ttacctcatg gaagaaatgg
     1741 gcctcacacc agctcagttt atcgatctca aggcgctcat gggtgataag tcggataata
     1801 tccctggggt gaccaaagtc ggtgaaaaga cgggtattaa gctcttgctg gagtatggtt
     1861 cgcttgaggg gatttatgaa aatattgatg gaatgaagac ttctaagatg aaggaaaatc
     1921 tcatcaatga caaggaacag gcctttttgt ctaaaacact agcgaccatt gataccaagg
     1981 caccgattgc gattggttta gaggacttgg tctatagtgg tccagatgtt gaaaatcttg
     2041 ggaaatttta cgatgagatg ggattcaaac agctcaagca ggctttaaat gtgtcgtcag
     2101 ctgatgtggc taagggtttg gattttacta ttgttgacca aatcagtcaa gatatgctga
     2161 gtgaagagtc tatcttccac tttgagcttt ttggtgagaa ttaccatacg gataatttgg
     2221 ttggatttgc ctggtcttgt gaggataagc tctatgccac agacaagctt gagctgttgc
     2281 aagacccgat tttcaaggat ttcttagaaa aaacatctct gagagtttat gactttaaga
     2341 aggttaaagt tcttttgcaa cgttttggtg tggatttgca ggcgcctgct tttgacatcc
     2401 gtttggctaa atacctcctt tcgactgtgg aggacaatga aattgcgacc atcgctagtc
     2461 tttatggtca gacttacttg gttgatgatg aaactttcta cggtaagggt gttaaaaagg
     2521 ccattcctga acgtgagaaa ttcttggaac acttagcttg taaacttgct gttttggtag
     2581 aaacagagcc tattttactt gaaaaactca gcgaaaatgg gcaattagag cttctttatg
     2641 atatggagca acctctggct tttgttcttg ccaagatgga aattgctggg attgtggtca
     2701 agaaagagac cttgcttgag atgcaggctg aaaatgagct tgtcattgaa aaactgactc
     2761 aagagattta cgagctggct ggtgaggagt ttaatgtcaa ctcgcctaag cagttgggcg
     2821 tgcttctctt tgagaaattg ggacttcctc tagaatacac taagaaaacc aagacaggtt
     2881 attcgacagc agtggatgtg ttggagcgtc tcgctcctat tgctccgatt gttaagaaaa
     2941 tcctggatta ccgtcaaatt gctaagattc aatctactta tgtaattggc ttgcaggact
     3001 ggattttggc tgatggaaag attcatactc gctatatgca ggatttgacc cagaccgggc
     3061 gtttgtctag tgtggatcca aacttgcaaa atattcctgc ccgattggaa caagggcgct
     3121 tgattcggaa ggcttttgtg ccagagtggg aggatagtgt gctactcagc tctgactatt
     3181 cacagattga attgcgcgtt ttggcgcata tttctaagga tgagcacttg attaaggcct
     3241 tccaagaggg ggcagatatc catacttcga cagccatgcg ggtctttggc attgagcgtc
     3301 ctgataatgt gactgcaaat gaccgtcgca atgccaaggc agttaacttt ggagtggttt
     3361 atgggatttc agactttggc ttgtctaata atttgggaat tagtcgtaag gaagccaaag
     3421 cctacattga tacctacttt gaacgttttc cagatattaa aaactacatg gatgaagtgg
     3481 tgcgggaggc gcgtgataag ggctatgtag agaccctctt taagcgtcgc cgtgagttgc
     3541 cagatatcaa ttcgcgcaac ttcaatattc gtggttttgc ggagcgaact gctatcaact
     3601 cacctatcca gggttcggca gcagatattc tcaagattgc catgattcag ctggataaag
     3661 ccttggttgc aggtggttat cagactaaga tgctgttaca agtgcacgat gaaatcgtcc
     3721 ttgaagtgcc taaatctgaa ttggtagaga tgaaaaaatt ggtgaaacaa accatggaag
     3781 aagccattca actcagtgtt cctcttatcg cagatgagaa tgaaggggca acctggtacg
     3841 aggctaaata aaaagggggc tagtcctcct tttttgtagt ataattctgc aaaccttttc
     3901 aaaatgtgct atactgatga aaaaggagga tttctatgag tcaagaattt atcaatccaa
     3961 gtgatggcgt gattcgtcag tatctcgcaa cgagtaaaac ccttgctgtg gtgggtttgt
     4021 ctgaccgtga agaaacaacc agcaatcgag taacaaagga aatgcaggct cggggctata
     4081 aaatcatccc agtcaatccc aaggcggcag gtggcgaaat cttgggtgaa aaggcttatg
     4141 ctagcctcgc tgaaattcct tttcctgtag atattgtcaa tgtttatcgt cgcagtgaat
     4201 ttctgcccga tgtggcgcgt gattttctca aagctgatgc caagattttt tgggcacagc
     4261 taggacttga aagtttagaa gcgaaagaga ttttgcgtga tggtggatgt gatgatatcg
     4321 tgatgaatcg ctgtatcaag agagaacata ctcgcttgat tgaggaagca taagaaaaag
     4381 gtagctgatg ggctaccttt tgtgttatac tcaatgaaaa tcaaagagca cactagcaaa
     4441 ctaggaaact agccgcgggc tgctcaaaac accgttttga ggttg
//
LOCUS       DBEJHE010000062         4470 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC4 isolate 671759
            SAMN38261586-rid24793303.denovo.62, whole genome shotgun sequence.
ACCESSION   DBEJHE010000062 DBEJHE010000000
VERSION     DBEJHE010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261586
            Sequence Read Archive: SRR26833752
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 4470)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4470)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576136.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576136.1
            Genome Coverage       :: 109x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 19:48:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,067
            CDSs (total)                      :: 2,029
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 131
            CDSs (without protein)            :: 131
            Pseudo Genes (ambiguous residues) :: 0 of 131
            Pseudo Genes (frameshifted)       :: 64 of 131
            Pseudo Genes (incomplete)         :: 59 of 131
            Pseudo Genes (internal stop)      :: 46 of 131
            Pseudo Genes (multiple problems)  :: 32 of 131
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4470
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261586-rid24793303.denovo.62"
                     /strain="GPSC4"
                     /isolate="671759"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            19..693
                     /locus_tag="ACL3EZ_002004"
     CDS             19..693
                     /locus_tag="ACL3EZ_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003025968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VIT family protein"
                     /protein_id="HGR0393513.1"
                     /translation="MDSNFAGRLNILRAGVLDANDGIISIAGVVIGVASATTNIWIIF
                     LSGFTAILAGAFSMAGGEYVSVSTPKDTEEAAVSREKLLLDQDRELAKKSLYAAYIQN
                     GEFKTSAQLLTNKIFLKNPLKALVEEKYGIEYEEFTNPWHAAISSFVAFFLRSLPPML
                     SVTIFPSDYRIPATVLIVGVALLLTGYTSARLGKAPTKTAMIRNLAIGLLTMGVTFLL
                     EQLFSI"
     gene            complement(735..2723)
                     /locus_tag="ACL3EZ_002005"
     CDS             complement(735..2723)
                     /locus_tag="ACL3EZ_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0393514.1"
                     /translation="MFRLTNKLAVSNLIKNRKLYYPFALAVLLAVTVTYLFYSLTFNP
                     KIAEIRGGTTIQATLGFGMFVVTLASAIIVLYANSFVMKNRSKELGIYGMLGLEKRHL
                     ISMTFKELVVFGILTVGAGIGIGALFDKLIFAFLLKLMKLKVELVATFQTKVVITVLV
                     VFGLIFLGLMFLNALRIARMNALQLSREKASGEKKGRFLPLQTILGSISLGIGYYLAL
                     TVKDPLTALTTFFIAVLLVIFGTYLLFNAGITVFLQILKKNKKYYYQPNNLISVSNLI
                     FRMKKNAVGLATIAILSTMVLVTMSAATSIFNSSESFKKVLNPHDFGVSGQNVEKEDL
                     DKLLSQFASDKGYKIKEKEVLRYTYFAVANQEGTKLTIFEKGQNRVQPKTVFMVFDQK
                     DYENMTGQKLSLSGNEVGLFAKNDGLKGQKALTLNDHQFSVKEEFTKDFIVNHVPNKF
                     NILTTDYNYLVVPDLQAFLDQFPDSAIYNQFYGGMNVDASEEEQLKVAEEYENYLNQF
                     NAQLDTEGSYVYGSNLADASSQMSALFGGVFFIGIFLSIIFMVGTVLVIYYKQISEGY
                     EDRERFIILQKVGLDQKQIKQTINKQVLTVFFLPLLFAFIHLAFAYHMLSLILKVIGV
                     LDTTMMLIVTLSICAIFLIAYVLIFMITSRSYRKIVQM"
     gene            complement(2725..3483)
                     /locus_tag="ACL3EZ_002006"
     CDS             complement(2725..3483)
                     /locus_tag="ACL3EZ_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0393515.1"
                     /translation="MTLLDVKHVQKIYKTRFQGNQVEALKDIHFTVEKGDYVAIMGES
                     GSGKSTLLNILAMLDKPSRGQVYLNGTDTATIKNSQASSFRREKLGFVFQDFNLLDTL
                     SVKDNILLPLVLSRRPITEMMKKLVVTAENLGINQLQEKYPYEISGGQKQRVAVARAI
                     ITEPEILLADEPTGALDSKSSAALLDVFDEINERGQTILMVTHSTAAASRAKRVLFIK
                     DGIFYNQIYRGEKTERQMFQEISDTLTVMASEVN"
     gene            3911..4102
                     /locus_tag="ACL3EZ_002007"
     CDS             3911..4102
                     /locus_tag="ACL3EZ_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0393516.1"
                     /translation="MKHKEHILIGFLYLLSPFIGQLLVEHTHFISTEFTGTAYVICWL
                     SVVISIHHFSKNVLSQQQK"
BASE COUNT         1371 a          875 c          865 g         1359 t
ORIGIN      
        1 tcagaaacaa atcacgaaat tgattcaaat tttgcaggtc gtttaaatat cctgcgtgcg
       61 ggtgttcttg atgctaacga tggaattatt tccattgctg gtgtggttat cggagttgcc
      121 agtgccacga ccaatatctg gattatcttt ttatcaggtt ttacggctat cttagctggt
      181 gccttttcaa tggctggtgg agaatatgta tccgtttcaa ctccaaaaga taccgaggaa
      241 gctgccgttt cgcgagaaaa actcttgcta gaccaagata gggaactagc caaaaaatcc
      301 ctctatgctg cttatatcca aaatggagaa ttcaaaactt ctgcccaact cttgaccaat
      361 aagatctttc ttaaaaatcc actcaaggct ctggtagagg aaaaatatgg gattgagtat
      421 gaagaattta ccaatccttg gcacgctgcc atttctagct tcgttgcctt tttccttaga
      481 agtttgcctc caatgctgtc agtgaccatt tttccaagtg attaccgcat ccctgctacc
      541 gtccttattg tcggtgtggc ccttcttctc actggttaca caagtgctag acttggaaaa
      601 gccccaacca aaacagctat gattcggaac cttgctattg gtctcttgac catgggagtt
      661 accttcctgc tcgaacaact tttcagcatt tagaatacaa gaaatacctc gattttgaag
      721 tcgaggtatc ttttttacat ttgcacaatc ttgcgataac ttcttgaagt aatcatgaaa
      781 atcagcacat aggcgatgag gaagatagcg cagatagaca aggtcacaat caacatcata
      841 gtcgtatcca gtacaccaat cacttttaaa atcaggctaa gcatatggta ggcaaaggcg
      901 agatgtatga aggcaaagag caaaggaagg aagaaaacag ttaaaacctg tttgttgatg
      961 gtttgcttga tttgcttttg gtccaaaccg actttctgca agataataaa gcgttcacgg
     1021 tcttcgtagc cttcagaaat ttgtttgtag tagatgacca gaacagttcc gaccataaag
     1081 ataatggata ggaaaatacc gataaagaag acaccaccaa agagggcact catctgagaa
     1141 ctagcatctg ctagattgct accataaaca tagctacctt ctgtgtctaa ttgagcatta
     1201 aattgattga ggtagttttc atactcctca gcgaccttga gttgttcttc ttcgctggca
     1261 tctacattca taccaccgta aaactgatta tagatagccg aatctgggaa ttgatccaaa
     1321 aaggcttgta aatcaggaac aacaaggtaa ttgtaatcag tagtcaagat attaaactta
     1381 tttggaacat ggttgacaat aaaatcttta gtaaattctt ctttgacaga aaattgatga
     1441 tcatttagag ttagagcttt ctgtcctttc agtccgtcat ttttggcaaa gagaccgacc
     1501 tcatttcctg atagagacag tttttgacca gtcatatttt cataatcttt ttggtcaaat
     1561 accatgaaaa ctgtttttgg ttggacacgg ttttgtcctt tttcaaaaat agttaacttg
     1621 gttccttctt gattcgcaac agcaaagtaa gtgtaacgaa gcacttcttt ctctttaatc
     1681 ttataacctt tgtcacttgc aaactggctc aagagtttgt ccaaatcttc tttttcaaca
     1741 ttttgccctg aaaccccaaa atcatgagga tttagaactt ttttaaagct ttctgaggaa
     1801 ttgaaaatgc ttgtcgctgc tgacatggtt accaaaacca ttgttgacaa gatagcgatg
     1861 gtggctagtc caactgcatt tttcttcata cggaaaatca agttagaaac agatatgaga
     1921 ttatttggtt ggtaatagta tttcttattt ttctttaaga tttggaggaa aacggtaatc
     1981 cctgcattaa acaagagata agtcccaaag ataaccagta aaacagctat gaagaaggtt
     2041 gttaaggctg taagaggatc ttttaccgta agggcaagat aatagccaat tcctaaactt
     2101 atggaaccaa gaatggtttg gagaggaagg aagcgacctt ttttctctcc actagctttc
     2161 tcacgagaga gctggagggc attcatacgg gcgattcgaa gggcattcag gaacatgagg
     2221 cctaggaaaa tcaaaccgaa gacaacaagc actgtaatga caactttcgt ctggaaggta
     2281 gcaaccagct caaccttcaa tttcattagt ttgagcagga aagcgaaaat taacttgtca
     2341 aacaaggctc caataccgat acccgctcca acagttagaa tcccaaatac cactaactcc
     2401 ttaaaggtca tactgataag atgacgcttc tccaagccca acatgccata aattcctagt
     2461 tccttggaac ggttcttcat gacaaaacta ttggcataga gaacgataat ggctgacgca
     2521 agggtgacga caaacatacc aaatccaagt gtagcctgaa tggttgttcc tccacggatt
     2581 tccgcaatct taggattgaa ggttagagag taaaagagat aggtgacagt gactgccaag
     2641 agaacagcca gcgcaaaagg atagtagagt ttgcggtttt taatcaagtt cgataccgct
     2701 aacttattgg ttaatcgaaa catactaatt cacctcgctt gccatgacag tcaaggtatc
     2761 agagatttct tggaacatct gacgttctgt cttctctcca cggtagattt gattgtaaaa
     2821 aatgccgtct ttgataaaga gtacacgttt agctctgcta gctgctgctg ttgagtgggt
     2881 taccatgaga atggtttggc cgcgctcatt gatttcatca aagacatcaa gtaaggctgc
     2941 agatgacttg gagtcaagag ctcctgtcgg ttcgtccgca aggagaattt caggttcagt
     3001 gatgatggcg cgtgctactg ctacacgctg tttctggcca ccagaaatct cgtaagggta
     3061 cttctcttgt aattggttta ttcccagatt ctcagctgtc accaccaatt tcttcatcat
     3121 ctctgtaata ggtcttcttg acaagacaag cggaagcaag atattgtcct taacagacag
     3181 agtatctagc aagttaaagt cttggaagac aaatcctagc ttttcacgcc ggaaactaga
     3241 agcctgtgaa tttttaatag ttgctgtatc agttccgttt aggtaaacct gcccacgact
     3301 tggtttatcc agcatagcta ggatattgag cagagtggat ttaccagaac cagactcacc
     3361 catgatagca acgtagtcac ccttttctac ggtgaagtga atatccttga gggcctctac
     3421 ttggttgccc tgaaaacgag ttttataaat tttttgaacg tgttttacat ctaaaagtgt
     3481 catgagaatc tcctttctta atatcccatc aaatgaaatg tagcttgcat catagtgcat
     3541 cccagctgaa tgcgctcaat ttctttgtga cttggttttc tagttttctt atgtaagatt
     3601 tgtttcatga tgttactcct ttgttcttta tgagtctagt ttacatcaaa aaaagaccgc
     3661 ttgccataac ctaaccttac aaaagagact ttaatcttac atttttgtaa gattgggtga
     3721 aatataagca aaattactta gaaaatgatt tgatttccta tttttaaagt tgtaaaatat
     3781 aagtatgaaa aggcttactt taaaaaggag gaagcgggaa ctaacatttt agtaaggtta
     3841 cctagataac atgccattca atttaacact tgcaagtcgt tcaacctata aggaaagaag
     3901 gtgcgcttta atgaaacata aagaacatat actcatcgga tttctctatc tgctctctcc
     3961 attcatcggt cagctcttag ttgaacacac acactttatc agtacagaat ttaccggcac
     4021 tgcttatgtt atttgctggt tatcagttgt tatcagcatc caccattttt ccaaaaatgt
     4081 attgtctcaa cagcaaaaat agattaaaaa actgcgttta aattactgct tttatagtaa
     4141 aatgaaataa gaacaggaca aatcgatcag gacagtcaaa tcgatttcta acaatttttt
     4201 agaagtatag gtgtcctatt ctagttccaa tccactatag tttgtggatg aagctggcga
     4261 aatattatta atactattca aaaatcaaag tgcaaactat atcaacttca cattgccgac
     4321 taaattacag cctgcggctg gcttcctagt ttgcactttg atttttaggt tctataatat
     4381 ttgtagtggg taaatcccct atggatatta tggagcctat ttttgtgtag aaaaaaagtc
     4441 ccataagatc tataatgaaa agcgatcaaa
//
LOCUS       DBEJHE010000063         4446 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC4 isolate 671759
            SAMN38261586-rid24793303.denovo.63, whole genome shotgun sequence.
ACCESSION   DBEJHE010000063 DBEJHE010000000
VERSION     DBEJHE010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261586
            Sequence Read Archive: SRR26833752
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 4446)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4446)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576136.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576136.1
            Genome Coverage       :: 109x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 19:48:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,067
            CDSs (total)                      :: 2,029
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 131
            CDSs (without protein)            :: 131
            Pseudo Genes (ambiguous residues) :: 0 of 131
            Pseudo Genes (frameshifted)       :: 64 of 131
            Pseudo Genes (incomplete)         :: 59 of 131
            Pseudo Genes (internal stop)      :: 46 of 131
            Pseudo Genes (multiple problems)  :: 32 of 131
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4446
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261586-rid24793303.denovo.63"
                     /strain="GPSC4"
                     /isolate="671759"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(58..1068)
                     /locus_tag="ACL3EZ_002008"
     CDS             complement(58..1068)
                     /locus_tag="ACL3EZ_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family protein"
                     /protein_id="HGR0393517.1"
                     /translation="MSFLSKNGAGILACLLISILSWYLGGFFPVIGAPVFAIFIGMLL
                     HPFLSSYKQLDAGLTFSSKKLLQYAVVLLGFGLNISQVFAVGQSSLPVILSTISIALI
                     IAYLFQRFFALDTKLATLVGVGSSICGGSAIAATAPVIHAKEKEVAQAISVIFFFNVL
                     AALIFPTLGTWLHLSNEGFALFAGTAVNDTSSVTAAASAWDSLYQSNTLESATIVKLT
                     RTLAIIPITLFLSYWQSRQQENKQSLQLKKVFPLFILYFILASLLTTLLTSLGVSSSF
                     FTPLKQLSKFLIVMAMSAIGLKTNLVAMVKSSGKSIVLGAICWIAIILTTLGMQTLIG
                     IF"
     gene            1217..2386
                     /locus_tag="ACL3EZ_002009"
     CDS             1217..2386
                     /locus_tag="ACL3EZ_002009"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HGR0393518.1"
                     /translation="MDLTKRFNKQLDKIQVSLIRQFDQVISEIPGVLRLTLGEPDFTT
                     PDHVKEAAKRAIDQNQSYYTGMSGLLTLRQAASDFVKEKYQLDYAPENEILVTIGATE
                     ALSATLTAILEEGDKVLLPAPAYPGYEPIVNLVGAEIVEIDTTENGFVLTPEMLEKAI
                     LEQGDKLKAVILNYPANPTGITYSREQLEALAAVLRKYEIFVVCDEVYSELTYTGEAH
                     VSLGTMLRDQAIIINGLSKSHAMTGWRLGLIFAPATFTAQLIKSHQYLVTAANTMAQH
                     AAVEALTAGKNDAEPMKKEYIQRRDYIIEKMTALGFEIIKPDGAFYIFAKIPAGYNQD
                     SFAFLKDFAQKKAVAFIPGAAFGRYGEGYVRLSYAASMETIKEAMKRLEEYMREA"
     gene            2383..3153
                     /gene="recO"
                     /locus_tag="ACL3EZ_002010"
     CDS             2383..3153
                     /gene="recO"
                     /locus_tag="ACL3EZ_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000616164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HGR0393519.1"
                     /translation="MIQSITSQGLVLYNRNFREDDKLVKIFTEQVGKRMFFVKHAGQS
                     KLAPVIQPLVLARFLLRINDDGLSYIEDYHEVMTFPKINSDLFVMAYATYVAALADAS
                     LQDNQQDAPLFAFLQKTLELMEAGLDYQVLTNIFEIQILTRFGISLNFNECVFCHRVG
                     QAFDFSFKYGACLCPEHYHEDDRRCHLNPNIPYLLNQFQAIDFETLETISLKPGIKQE
                     LRQFMDQLYEEYVGIHLKSKKFIDSLADWGQLLKEEKK"
     gene            3150..4142
                     /gene="plsX"
                     /locus_tag="ACL3EZ_002011"
     CDS             3150..4142
                     /gene="plsX"
                     /locus_tag="ACL3EZ_002011"
                     /EC_number="2.3.1.274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000717456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043811 - phosphate:acyl-[acyl carrier
                     protein] acyltransferase activity [Evidence IEA];
                     GO_process: GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HGR0393520.1"
                     /translation="MKKIAVDAMGGDYAPQAIVEGVNQALSDFSDIEVQLYGDEAKIK
                     QYLTATERVSIIHTDEKIDSDDEPTRAIRNKKNASMVLAAKAVKDGEADAVLSAGNTG
                     ALLAAGFFIVGRIKNIDRPGLMSTLPTVDGKGFDMLDLGANAENTAQHLHQYAVLGSF
                     YAKNVRGIAQPRVGLLNNGTESSKGDPLRKETYELLAADESLNFIGNVEARDLMNGVA
                     DVVVADGFTGNAVLKSIEGTAMGIMGLLKTAITGGGLRAKLGALLLKDSLSGLKKQLN
                     YSDVGGAVLFGVKAPVVKTHGSSDAKAVYSTIRQIRTMLETDVVAQTAREFSGE"
     gene            4148..4381
                     /locus_tag="ACL3EZ_002012"
     CDS             4148..4381
                     /locus_tag="ACL3EZ_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HGR0393521.1"
                     /translation="MTEKEIFDRIVTIIQERQGEDFVVTESLSLKDDLDADSVDLMEF
                     ILTLEDEFSIEISDEEIDQLQNVGDVVKIIQGK"
BASE COUNT         1291 a          851 c         1143 g         1161 t
ORIGIN      
        1 aacatatacc tacggcaagg cgacgttgac gtggtttgaa gagattttcg aagagtgtta
       61 gaaaatgccg ataagggtct gcataccaag agtggtgagg atgatggcaa tccagcagat
      121 ggctccaaga acaatggatt ttccactgga tttgaccata gcgaccagat tggttttgag
      181 accgatagca ctcatggcca tgacaataag gaatttagag agttgtttga gaggggtaaa
      241 gaaactactg gacacaccta gagaggtgag tagtgtagtg aggagagagg caaggataaa
      301 gtaaaggata aaaagtggga agactttttt cagttgtagg ctttgcttgt tttcttgttg
      361 gcgactttgc cagtaggata gaaagagcgt gatagggata atggccaaag tacgtgtgag
      421 tttaacaatg gttgcagact cgagggtatt gctttggtaa agactgtccc aagcgctggc
      481 ggcagccgtt acagaggaag tgtcgttgac cgcagtccct gcaaagaggg cgaagccttc
      541 attggataga tgaagccagg tgccgagggt tggaaagatg agcgcagcca agacattgaa
      601 gaaaaagata acggaaatgg cttgggctac ttccttttcc ttagcatgga taacaggcgc
      661 tgtcgctgca atggcagaac ccccacagat agaagaacct actccaacca aggtagccag
      721 ttttgtatcc agtgcaaaga aacgctggaa gaggtaggca ataatcagag ctattgagat
      781 agtggacagg atgacaggga gtgaagattg gccaactgcg aagacctgcg agatattgag
      841 accaaaacca agcaagacaa cggcatattg gagcaacttc ttggaactaa aggtcaaacc
      901 agcatccagt tgtttatagg acgagagaaa gggatgtagg agcatgccta tgaaaatggc
      961 aaaaacgggc gcgccaatca cagggaagaa tcctcctaag taccaagata ggatggaaat
     1021 gagaaggcag gccaagatac ctgctccatt ttttgataga aatgacataa aaacctccaa
     1081 ataaaatcta ttaccattat agacctataa acaggaaaag taaaatagaa agtggaaagc
     1141 tattctctaa tgtatttttg cggtcggggg gcttttgtag tataatagag atacgttttg
     1201 aaagtaggag gtatctatgg acttaactaa gcgctttaat aaacagttag ataaaattca
     1261 agtttcgttg attcgtcagt ttgaccaggt tatttcggag attcctgggg tcttgcgttt
     1321 gaccttgggg gaacctgatt ttacaacgcc agaccatgtc aaggaggcgg ccaagcgagc
     1381 gattgatcag aaccaatcct actatacagg gatgagtggt ctgctgactc tacgtcaggc
     1441 agccagtgac tttgttaagg aaaagtacca actggactat gctcctgaaa atgaaatctt
     1501 ggttacaatt ggggcgacag aggctttatc tgcgactttg acggctattt tggaagaggg
     1561 agacaaggta cttttgccag ctcctgctta tccaggctat gaaccgattg ttaacttagt
     1621 tggggcagaa attgttgaga ttgatacgac tgaaaatggt tttgtcttga ctcctgagat
     1681 gttggagaag gccattttgg agcagggtga taagctcaag gcggttattc tcaactatcc
     1741 agccaatccg acaggaatta cctacagtcg agagcagtta gaggccttgg cagctgtttt
     1801 acgcaagtac gaaatttttg ttgtctgtga tgaggtttac tcagaattga cctacacagg
     1861 cgaagcccat gtgtctctag gaacgatgtt gagagaccag gctattatta tcaatggttt
     1921 gtctaaatcg catgccatga caggttggcg tttggggctg attttcgctc ctgcgacctt
     1981 cacagcccag ttaatcaaga gtcaccagta cttggtcact gccgcaaata ccatggcgca
     2041 acatgctgca gtagaagcct tgacggctgg taaaaacgat gcggagccca tgaagaagga
     2101 atatatccag cgtcgggact atatcatcga aaaaatgact gctcttggtt ttgagattat
     2161 caaaccagac ggtgccttct atatttttgc taaaattcca gcgggctaca atcaagactc
     2221 ctttgctttt ctgaaggatt ttgctcagaa gaaggccgtt gcctttatcc ctggtgcagc
     2281 ctttggacgt tacggggaag gctacgtccg cctatcttat gcagccagca tggagactat
     2341 caaagaagcc atgaaacgac ttgaggagta catgagagaa gcatgattca gtctatcacg
     2401 agtcaaggct tggtgcttta caatcgcaat tttcgtgagg atgacaagct cgtcaaaatt
     2461 tttacagagc aggttggcaa acgcatgttt tttgtcaaac acgctggtca gtctaagctg
     2521 gcgcctgtta ttcagccctt ggtgctggca cgatttctct tgcgaatcaa tgatgacgga
     2581 ctcagttaca tcgaagacta tcatgaggtc atgacttttc ccaagattaa tagtgacctc
     2641 tttgtcatgg cctatgcgac ctatgtggca gctcttgcag atgctagttt gcaggacaat
     2701 cagcaggatg ctcccttgtt tgcttttttg caaaagactt tggagttgat ggaagcaggc
     2761 ttggattatc aggttttgac caatattttt gaaattcaaa ttttgactcg atttggaatc
     2821 agcctcaatt ttaatgagtg tgtcttctgc catcgggttg gtcaggcttt tgacttttct
     2881 ttcaaatatg gagcctgtct ctgtccagag cattatcatg aggatgatag acgttgccat
     2941 ctcaatccca atatccccta tctgctcaat caatttcaag ctattgattt tgagactttg
     3001 gagaccattt cgctcaagcc tggaatcaag caagagctac gccaatttat ggatcaacta
     3061 tatgaagagt acgttgggat tcacctaaaa tcaaagaaat ttattgattc cctagcagac
     3121 tggggacaat tactaaaaga ggaaaagaaa tgaaaaaaat cgcagtagat gccatggggg
     3181 gcgattacgc acctcaggcc atcgttgagg gtgtcaatca agccctatct gacttttcag
     3241 atatcgaggt tcaactttac ggagatgaag ctaaaatcaa gcaatatctg acagcgacag
     3301 agcgcgtcag cattatccat acggatgaga agattgattc ggatgatgaa cctacgagag
     3361 ctattcggaa taagaaaaat gccagtatgg tattggcagc caaggctgtc aaagatggtg
     3421 aagcagacgc tgtcctttcg gctgggaata caggtgcctt gttggcagca ggattcttca
     3481 tcgtgggtcg tatcaagaat atcgaccgtc ctggactcat gtctaccttg cctaccgttg
     3541 atggaaaagg ttttgacatg ctagaccttg gtgccaatgc agaaaataca gcccagcacc
     3601 tccatcaata tgcggttcta ggttccttct atgctaaaaa tgtccgtggc attgcgcaac
     3661 cacgcgttgg tttgctcaac aacggaacag agagtagcaa gggcgacccg cttcgtaagg
     3721 aaacttatga attactggcg gctgatgaaa gtttgaactt tatcggaaac gtggaagcgc
     3781 gtgatttgat gaatggcgtt gcagatgttg ttgtggcaga tggtttcacg ggaaacgctg
     3841 tgctcaaatc catcgaaggg acagctatgg gaatcatggg cttgctcaag acagctatta
     3901 caggtggtgg tcttcgagcg aaactaggtg ccctccttct caaggacagc ctcagtggtt
     3961 tgaaaaaaca gctcaattat tcagatgttg gtggagcggt cttgtttggt gttaaggcac
     4021 ctgttgtcaa gactcatggc tcaagcgatg ccaaggctgt ttatagtacg attcgtcaga
     4081 tccgtaccat gctagaaaca gacgtggttg cccagactgc gcgtgaattt tcaggagaat
     4141 aaaagagatg acagaaaaag aaatttttga ccgtattgtg accattatcc aagagcgaca
     4201 gggagaggac tttgtcgtga cagaatcctt gagtctgaaa gacgatttgg atgcggattc
     4261 tgttgacttg atggagttta tcttgactct ggaagatgaa tttagtatcg aaatcagcga
     4321 tgaagaaatt gaccaactcc aaaacgtagg agatgtggtt aaaatcattc aaggaaaata
     4381 gcaatcggag ttccaagtca acggaagtag atggttttta gaaatgagaa atatcggaca
     4441 agctgg
//
LOCUS       DBEJHE010000064         4390 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC4 isolate 671759
            SAMN38261586-rid24793303.denovo.64, whole genome shotgun sequence.
ACCESSION   DBEJHE010000064 DBEJHE010000000
VERSION     DBEJHE010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261586
            Sequence Read Archive: SRR26833752
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 4390)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4390)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576136.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576136.1
            Genome Coverage       :: 109x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 19:48:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,067
            CDSs (total)                      :: 2,029
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 131
            CDSs (without protein)            :: 131
            Pseudo Genes (ambiguous residues) :: 0 of 131
            Pseudo Genes (frameshifted)       :: 64 of 131
            Pseudo Genes (incomplete)         :: 59 of 131
            Pseudo Genes (internal stop)      :: 46 of 131
            Pseudo Genes (multiple problems)  :: 32 of 131
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4390
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261586-rid24793303.denovo.64"
                     /strain="GPSC4"
                     /isolate="671759"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(59..703)
                     /locus_tag="ACL3EZ_002013"
                     /pseudo
     CDS             complement(59..703)
                     /locus_tag="ACL3EZ_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365310.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
     gene            complement(812..1330)
                     /locus_tag="ACL3EZ_002014"
     CDS             complement(812..1330)
                     /locus_tag="ACL3EZ_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HGR0393522.1"
                     /translation="MRTYENKEELKAEIEKTFEKYILEFDNIPENLKDKRADEVDRTP
                     AENLAYQVGWTNLVLKWEEDERKGLQVKTPSDKFKWNQLGELYQWFTDTYAHLSLQEL
                     KAKLNENIHSISAMIDSLSEEELFEPHMRKWADEATKTATWEVYKFIHVNTVAPFGTF
                     RTKIRKWKKIVL"
     gene            complement(1367..1495)
                     /locus_tag="ACL3EZ_002015"
                     /pseudo
     CDS             complement(1367..1495)
                     /locus_tag="ACL3EZ_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267199.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CD1845 family protein"
     gene            complement(1557..2426)
                     /gene="rsmI"
                     /locus_tag="ACL3EZ_002016"
     CDS             complement(1557..2426)
                     /gene="rsmI"
                     /locus_tag="ACL3EZ_002016"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0000451 - rRNA 2'-O-methylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HGR0393523.1"
                     /translation="MQIQKSFKGQSPYGKLYLVATPIGNLDDMTFRAIQTLKEVDWIA
                     AEDTRNTGLLLKHFDISTKQISFHEHNAKEKIPDLIGFLKAGQSIAQVSDAGLPSISD
                     PGHDLVKAAIEEEIAVVTVPGASAGISALIASGLAPQPHIFYGFLPRKSGQQKQFFDS
                     KKDYPETQIFYESPHRVADTLENMLEVYGDRSVVLVRELTKIYEEYQRGTISELLESI
                     AETSLKGECLLIVEGASQDVEEKGEEDLFLEIQARIQQGMKKNQAIKEVAKIYQWNKS
                     QLYAAYHDWEEKQ"
     gene            complement(2429..2746)
                     /gene="yabA"
                     /locus_tag="ACL3EZ_002017"
     CDS             complement(2429..2746)
                     /gene="yabA"
                     /locus_tag="ACL3EZ_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HGR0393524.1"
                     /translation="MDKKELFDALDDFSQQLLVTLADVEAIKKNLKSLVEENTALRLE
                     NSKLRERLGEVEADAPVKAKHVRESVRRIYRDGFHVCNDFYGQRREQDEECMFCDELL
                     YRE"
     gene            complement(2786..3676)
                     /locus_tag="ACL3EZ_002018"
     CDS             complement(2786..3676)
                     /locus_tag="ACL3EZ_002018"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HGR0393525.1"
                     /translation="MKQDQLKAWQPAQFDRFVRILEQDQLNHAYLFSGFFGSLEMAQF
                     LAKSLFCTDKVGVLPCEKCRSCKLIEQEEFPDVTLIKPVNQVIKTERIRELVGQFSQA
                     GIESQQQVFIIEQADKMHPNAANSLLKVIEEPQSEVYIFFLTSDEEKMLPTIRSRTQI
                     FHFKKQEEKLILLLEQMGLVKKKATLLAKFSQSRAEAEKLANQASFWTLVDESERLLT
                     WLVAKKKESYLQVAKLANLADDKEKQDQVLRILEVLCGQDLLQVRVRVILQDLLEARK
                     MWQANVSFQNAMEYLVLKEI"
     gene            complement(3673..4311)
                     /gene="tmk"
                     /locus_tag="ACL3EZ_002019"
     CDS             complement(3673..4311)
                     /gene="tmk"
                     /locus_tag="ACL3EZ_002019"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004798 - thymidylate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006233 - dTDP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HGR0393526.1"
                     /translation="MSKGFLVSLEGPEGAGKTSVLEALLPILKEKGVEVLTTREPGGV
                     LIGEKIREVILDPSHTQMDAKTELLLYIASRRQHLVEKVLPALEAGKLVIMDRFIDSS
                     VAYQGFGRGLDIEAIDWLNQFATDGLKPDLTLYFDIEVEEGLARIAANSDREVNRLDL
                     EGLDLHKKVRQGYLSLLDKEGNRIVKIDASLPLEQVVETTKAVLFDGMGLAK"
BASE COUNT         1218 a          993 c          704 g         1475 t
ORIGIN      
        1 tcgtaaacga ttcggattac gaatgaattt gattgctggt attatcaatc atgaactagg
       61 attctagttt tgcaggaagt ctaatgtaat tctcaagctg tgagttcatt atgatttgta
      121 aatcctatat atcttcagca gctaaaaaca cattttgaaa tgttccaagt ccgttttcac
      181 caaaactata ttctctctta ctatacttac tcttattatt ctctatatag ttagagtcaa
      241 ggttcttaac ctcttgaagt tcattttctt tacttctgag gttaaaatct tttacttctg
      301 aagttaagtt ttttgacttc tgtaagtcat tttcttttac ctgaaatata ctcataaagt
      361 ctttaacata aatgatgttc ggcttaccaa gtccaagcct tactctttcg atcagtccta
      421 ttcctttttt tatatcaagc tcatctaatg tttttatggc agttggcttt gagatatttc
      481 ttcttttcat aatttcttcg acagtaaaat agataaatac tctgccttcc ttgtctatcc
      541 agttattctt aaatgacatt cctgtctatt taagaagtat ggaataaagg ataattgctt
      601 ctgctgataa gccccgaaat tcttctctat caactaatat ctccggtact tttaagaagt
      661 taaatctttt cgcttctctg ttataaaaat attcaaagtc catgcaagat cacctccctt
      721 cttaaaaatt tgcaaagaaa aagacgatag tttttcttct atcgcctttg gtaaccattt
      781 ttatgaaatt ttttaaagtt aaaaatataa tttataatac tatcttcttc cattttctga
      841 ttttagttct gaaagttcca aaaggtgcaa ccgtatttac atgaataaac ttatacactt
      901 cccaagtcgc tgttttagtc gcttcatcag cccactttct catatgcggt tcaaataatt
      961 cttcctcact caacgaatca atcattgcag agatagaatg aatattttca tttaattttg
     1021 ctttcaactc ttgcagagat aaatgagcgt aggtatctgt gaaccactga tataattcac
     1081 caagttgatt ccatttaaat ttatccgatg gtgtttttac ttgaagcccc tttctttcat
     1141 cttcttccca tttaagaacc aagttggtcc aaccaacctg ataagcaagg ttttctgctg
     1201 gagttctgtc aacttcatca gctctcttat cttttaaatt ttctggaata ttatcaaatt
     1261 ctaaaatata tttctcaaat gttttctcta tctcagcttt tagttcttct ttattttcgt
     1321 atgttcgcaa aaaatcacct tctttctgat ttatcaatcc tttgatttaa aatgacctta
     1381 tttttctatt tataccttct aagaacgcta taactgctgc tccaaccatc ggtattccgt
     1441 atgggcttaa taaaaaactt aataccaaag cttctatacc aagtgataca tctttatatt
     1501 atcatcacta attaagttaa acagaaacag acagaattat tacatcctgt ctccctttat
     1561 tgtttttctt cccagtcgtg gtaggcagcg tagagttgac tcttattcca ctggtaaatc
     1621 ttagctactt ccttaatagc ttgatttttc ttcatacctt gctgaatacg agcttggatt
     1681 tctaagaaca agtcttcctc gcctttttct tccacatcct gactggcacc ttcaacaatc
     1741 agaagacatt cacccttgag agacgtttca gcaatgcttt ccagcaattc agaaattgta
     1801 cctctttggt attcttcata gattttggtc aattccctga ccaagacaac ggagcggtca
     1861 ccgtagactt ctagcatatt ttccaatgta tctgccacac gatggggcga ttcataaaaa
     1921 atctgagttt caggatagtc ttttttcgag tcgaaaaatt gcttttgctg gcctgatttt
     1981 ctcggtaaaa agccgtaaaa gatatgtggc tgcggcgcta aaccactggc aatcaaggcg
     2041 gaaattcctg cagaggcacc tggaactgta acaactgcaa tttcttcctc aatagctgcc
     2101 ttaaccaaat catgaccagg gtctgaaatg ctaggcaaac cggcatcaga gacctgagca
     2161 atactttgcc ctgctttcaa gaaaccaatc aaatcaggaa ttttttcctt ggcattgtgc
     2221 tcatgaaaac tgatctgctt ggtggaaatg tcaaaatgct tgagcaaaag ccctgtattg
     2281 cgcgtatcct cagcagcaat ccagtccact tctttcaagg tctggatagc acgaaaagtc
     2341 atatcatcta gattgccaat cggcgttgcc actagataca gcttgccata gggagactgc
     2401 cccttaaaac ttttttgaat ttgcatgctt actccctgta taacaactca tcacagaaca
     2461 tacattcttc gtcctgctct cgacgttgtc cataaaaatc attacatacg tgaaatccat
     2521 cacggtaaat acgacggaca ctttcgcgaa catgcttggc cttgacggga gcgtctgctt
     2581 ccacctcacc caagcgttct cgcaacttac tattttccaa gcgaagagct gtattttctt
     2641 ctaccaagct cttgagattt ttcttgatgg cttccacatc ggctaaggtt accaataatt
     2701 gttgggaaaa atcatccagc gcgtcaaata attctttttt gtccataaaa cagccctttc
     2761 ctttctttat cattcatttt tgagtttata tttctttcaa gaccagatat tccatggcat
     2821 tttgaaagct gacattagct tgccacattt ttctagcttc tagtaaatct tgtagaatca
     2881 ctcttactct tacctgcaag aggtcctgcc cacagagaac ttcaagaatc cgtaaaacct
     2941 gatcctgttt ttccttatca tctgccaagt tggctaattt ggcaacctgt agataacttt
     3001 cttttttctt agctactaac caagtcagca ggcgttcact ttcatcgacc aaggtccaaa
     3061 aacttgcctg attagccaac ttttctgctt cagctcgcga ttgactaaac ttagctaaaa
     3121 gagtcgcttt tttcttaaca agtcccattt gttctaagag taagataagt ttttcttctt
     3181 gctttttaaa gtggaagatc tgagtccgac ttcggattgt cggtaacatc ttttcctcat
     3241 cgctagtcaa gaagaaaata taaacttcac tctggggttc ttcgatgacc ttgagcagag
     3301 aattggctgc gttgggatgc attttatccg cttgctcgat aataaagacc tgttgctggc
     3361 tttcaatccc tgcttgagaa aactgtccca ccaattcccg aatgcgttct gtcttgatga
     3421 cctgattgac tggcttaatc aaggtgacat ctggaaactc ttcctgttca atcagcttgc
     3481 aacttcggca tttctcacat ggtaagacgc caactttatc cgtacaaaag aggctcttag
     3541 ctaaaaattg cgccatttcc aagcttccaa agaaacctga aaagagatag gcgtgattga
     3601 gctggtcttg ttctaagata cggacaaaac ggtcaaactg agctggttgc caagccttta
     3661 gttgatcttg tttcatttgg ccaagcccat tccgtcaaac aagacagcct tggtagtttc
     3721 cacaacttgc tccaaaggga gactagcatc aatcttgaca atgcgatttc cctctttatc
     3781 cagaagagaa aggtagcctt gacgaacttt tttatgcaag tccaaccctt ccaaatccaa
     3841 acgattaacc tcgcggtcac tattcgcagc aatacgagcc agcccttctt ccacctcgat
     3901 gtcaaaatag agtgtcaaat cgggtttgag gccatctgtc gcaaactgat tgagccagtc
     3961 aatggcttca atatctaagc cacgaccaaa tccctgatag gcaacagaac tatcgataaa
     4021 acgatccatg atgaccaact tgccagcttc aagggctgga agaacttttt ccaccaaatg
     4081 ctgtctgcga ctggcaatat agagaagtag ctctgtttta gcatccatct gagtatgact
     4141 tggatccaaa atcacttccc gaatcttctc cccaatcaag actccgccag gttcacgggt
     4201 cgtcaacacc tctactcctt tttcctttaa aattggtagc agagcctcta aaacactggt
     4261 cttgcctgct ccctctggtc cctcaagaga gactaaaaat ccttttgaca tgtctaactc
     4321 atttcttttt tactacttct attctatcaa aaaaataggg gtttgtgaca atctttttgt
     4381 cttctcattt
//
LOCUS       DBEJHE010000065         4225 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC4 isolate 671759
            SAMN38261586-rid24793303.denovo.65, whole genome shotgun sequence.
ACCESSION   DBEJHE010000065 DBEJHE010000000
VERSION     DBEJHE010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261586
            Sequence Read Archive: SRR26833752
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 4225)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4225)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576136.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576136.1
            Genome Coverage       :: 109x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 19:48:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,067
            CDSs (total)                      :: 2,029
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 131
            CDSs (without protein)            :: 131
            Pseudo Genes (ambiguous residues) :: 0 of 131
            Pseudo Genes (frameshifted)       :: 64 of 131
            Pseudo Genes (incomplete)         :: 59 of 131
            Pseudo Genes (internal stop)      :: 46 of 131
            Pseudo Genes (multiple problems)  :: 32 of 131
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4225
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261586-rid24793303.denovo.65"
                     /strain="GPSC4"
                     /isolate="671759"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(173..838)
                     /locus_tag="ACL3EZ_002020"
     CDS             complement(173..838)
                     /locus_tag="ACL3EZ_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001283913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006813 - potassium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HGR0393527.1"
                     /translation="MSDRTIGILGLGIFGSSVLAALAKQDMNIIAIDDHAERINQFEP
                     VLARGVIGDITDEELLRSAGIDTCDTVVVATGENLESSVLAVMHCKSLGVPTVIAKVK
                     SQTAKKVLEKIGADSVISPEYEMGQSLAQTILFHNSVDVFQLDKNVSIVEMKIPQSWA
                     GQSLSKLDLRGKYNLNILGFREQENSPLDVEFGPDDLLKADTYILAVINNQYLDTLVA
                     LNS"
     gene            complement(852..2231)
                     /locus_tag="ACL3EZ_002021"
     CDS             complement(852..2231)
                     /locus_tag="ACL3EZ_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000897732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015079 - potassium ion transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HGR0393528.1"
                     /translation="MLFKLSKEKIELGLSRLSPARRIFLSFALVILLGSLLLSLPFVQ
                     VESSRATYFDHLFTAVSAVCVTGLSTLPVAHTYNIWGQIICLLLIQIGGLGLMTFIGV
                     FYIQSKQKLSLRSRATIQDSFSYGETRSLRKFVYSIFLTTFLVESLGAILLSFRLIPQ
                     LGWGRGLFSSIFLAISAFCNAGFDNLGSTSLFAFQTDLLVNLVIAGLIITGGLGFMVW
                     FDLAGHVGRKKKGRLHFHTKLVLLLTIGLLLFGTATTLFLEWNNAGTIGNLPVADKVL
                     VSFFQTVTMRTAGFSTIDYTQAHPVTLLIYILQMFLGGAPGGTAGGLKITTFFVLLVF
                     ARSELLGLPHANVARRTIAPRTVQKSFSVFIIFLMSFLIGLILLGITAKGNPPFIHLI
                     FETISALSTVGVTANLTPDLGKLALSVIMPLMFMGRIGPLTLFVSLADYHPEKKDMIH
                     YMKADISIG"
     gene            complement(2841..3605)
                     /locus_tag="ACL3EZ_002022"
     CDS             complement(2841..3605)
                     /locus_tag="ACL3EZ_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
                     /protein_id="HGR0393529.1"
                     /translation="MIQKHAIPILEFDDNPQAVIMPNHEGLDLQLPKKCVYAFLGEEI
                     DRYAREVGADCVGEFVSATKTYPVYVINYKGEEVCLAQAPVGSAPAAQFMDWLIGYGV
                     EQIISTGTCGVLADIEENAFLVPVRALRDEGASYHYVAPCRYMEMQPEAIAAIEEVLE
                     DRGIPYEEVMTWTTDGFYRETAEKVAYRKEEGCAVVEMECSALAAVAQLRGVLWGELL
                     FTADSLADLDQYDSRDWGSEAFNKALELSLASVHHL"
     gene            3654..3836
                     /locus_tag="ACL3EZ_002023"
                     /pseudo
     CDS             3654..3836
                     /locus_tag="ACL3EZ_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691454.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-disulfide reductase"
     gene            3826..4122
                     /locus_tag="ACL3EZ_002024"
     CDS             3826..4122
                     /locus_tag="ACL3EZ_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000450185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HGR0393530.1"
                     /translation="METSISMADFYGKYQNENLELIDVREAHEFQAGHAPGAKNLPLS
                     TLEQGYKELKPDHEYYVICQGGVRSASTCQFLSSQGLTVTNVEGGMNAWPGQVE"
BASE COUNT         1362 a          996 c          804 g         1063 t
ORIGIN      
        1 cccgcagcta gtttcctagt ttgatctttg attttcattg agtattactc tctcttgtca
       61 cttccttcta ttttaccata aagtccagcc tttgaagaac ttttactaga agacaagggg
      121 cttctgtctc tatttgccat cttgggcatc aaaaaagagg ggtcatccct ctttacgaat
      181 tcaatgctac tagggtatcc aaatactggt tgttgatgac tgccaaaata taggtatctg
      241 ctttcaagag gtcatctggt ccaaattcaa catccaatgg ggaattttcc tgctctcgga
      301 aacccaaaat attcagattg tatttgccac ggaggtctaa tttactcaga ctttgacctg
      361 cccaagactg aggaattttc atctccacga tagacacatt tttatccaac tgaaagacat
      421 caacactatt atggaaaaga atggtctgtg ctagagactg tcccatttca tactctggcg
      481 agataaccga gtcagctcca atcttttcta gcactttctt agcggtctga cttttgacct
      541 tagcaataac agtcggtacc cccaaactct tacagtgcat aaccgcaagc acactcgact
      601 ccagattttc acctgtcgcg actacaacgg tatcgcaggt atcaatccct gctgatctca
      661 ataattcttc atctgtgatg tcaccaatca ctccacgcgc caaaactggc tcaaactgat
      721 tgatgcgctc tgcgtggtca tcaatagcga taatattcat atcctgcttg gctagggcag
      781 ctaggacact gctcccaaaa attcccaagc ccaaaattcc aatcgtacga tctgacatgc
      841 tctttccttt cttaaccaat actaatatct gctttcatat agtgaatcat atctttcttt
      901 tctggatggt aatctgccaa gctaacaaac aaggtcaagg gaccaattcg tcccataaac
      961 ataagtggca tgataacact gagagccaat ttcccaaggt caggagtcag atttgccgtt
     1021 acaccaactg tactaagagc tgaaatggtt tcaaatatga ggtggataaa gggaggattg
     1081 cctttggctg ttatccctag cagaatcaat cctatcaaga agctcatcaa aaagataata
     1141 aagacactaa aggatttttg aaccgttcgc ggcgcaatcg ttcgtctcgc aacattggca
     1201 tgaggcaagc ctagaagctc acttcgtgca aagaccaaga ggacaaaaaa tgtcgtaatc
     1261 ttgagtcccc cagctgttcc tccaggtgcc ccacctagaa acatctgtaa gatataaatc
     1321 aaaagagtca caggatgagc ctgagtataa tctatcgtag aaaagccagc tgttcgcatc
     1381 gtcactgttt gaaaaaagct aactaaaacc ttatcggcaa cagggagatt gccaatcgtt
     1441 ccagcattgt tccactcaag aaagagagta gttgccgttc caaataacaa caaacctata
     1501 gtcaacaata gtacaagctt cgtatgaaag tgcagacgtc cttttttctt tcttcctaca
     1561 tgaccagcca aatcaaacca gaccataaaa ccaaggccgc ctgtaataat caagcctgca
     1621 atcaccagat tgaccagtaa atcggtctga aaagcaaata aactggtgct ccctaaatta
     1681 tcaaaaccgg cattacagaa ggctgagatc gctagaaaaa tggaactaaa aagaccacgt
     1741 ccccagccaa gttgaggaat aaggcgaaaa ctaagcaaaa tagctcccaa gctctcaacc
     1801 aaaaaggtcg tgagaaaaat agaatagaca aactttctca aagatcgagt ttctccataa
     1861 ctaaaactat cctgaatagt tgcacggcta cgaagactaa gcttttgctt gctctggata
     1921 tagaaaaccc caataaaggt catgagccct agaccaccga tctgaatcaa gagcaaacag
     1981 attatttggc cccatatatt ataggtgtga gctactggaa gggttgagag acctgtcaca
     2041 cagactgcag agacagcagt gaaaagatga tcaaaataag tcgctcgtga gctttcaact
     2101 tggacaaagg gcaagctcaa aagaagagag cctagtaaaa tgaccaaggc aaaactcaaa
     2161 aaaatacgac gggctggcga taaacgagat aagcctagct ctattttttc cttagataat
     2221 ttgaataaca tgtttccatt gtaccataaa aagctcgaaa tgacttagat aggataaggc
     2281 aaaattcact aacaccaagc ctaaaaaatg ccaccttttt attgatagct taggcaagaa
     2341 caatacttga tagatgtgac tataggtcaa aaaagcaaga caggagcttt taacgccagc
     2401 tactctatat gcttttcagg agaaaatttc tctttttgat tataggcaat gagaaccaag
     2461 gcatcgctta gaaagctagt cacaggttgc tcaaaacact gttttgaggt tgtggataga
     2521 actgacgaag tcagctcaaa acactgtttt gaggttgcag atagaactga cgaagtcagt
     2581 aacatctata cggcaaggtg aagctgacct ggtttgaaga gattttcgaa gagtatcatt
     2641 tcatctcact ctaaatctta ccaacataaa acgcatagta tcaaaatttt catcacctga
     2701 tatgatacgt ttttctgatt ttaaagattt ttcccaacct caacatgcct aggacaagag
     2761 gaaggtgacc tcgtttaaac atatttttga aaagtatgag ctagacattt tatgataaaa
     2821 caaatccttt gccagtacaa ctaaaggtgg tgaacacttg ctaaactcag ttctagcgcc
     2881 ttattaaaag cttccgagcc ccagtcacga ctgtcgtact ggtccaagtc cgctagagaa
     2941 tctgctgtga acaacaattc accccagaga accccacgca attgagctac tgccgcaaga
     3001 gcagaacact ccatctccac aacagcacag ccttcttcct tacgataagc caccttttca
     3061 gccgtttctc ggtaaaaacc gtctgtcgtc caggtcatga cttcttcata aggaatccct
     3121 ctgtcttcca aaacttcctc aatagcagca atagcctctg gctgcatttc catataacga
     3181 caaggtgcca catagtggta actggctccc tcatctcgca aagcgcgaac agggactaga
     3241 aaggcatttt cctctatatc agctaggaca ccacaggtcc cagtagagat aatctgctcc
     3301 acaccatagc caatcaacca atccataaac tgggctgctg gagcggagcc aacaggagcc
     3361 tgagccagac agacctcctc acccttgtag ttgatgacat agactggata ggtcttggta
     3421 gcagaaacga attcgccgac acaatccgcc cctacttccc ttgcatagcg gtcaatctcc
     3481 tcacctaaaa atgcataaac acacttcttt ggcaactgca agtccagccc ctcgtgattg
     3541 ggcatgataa ccgcctgagg attgtcatca aactctaaaa taggaatcgc atgtttctga
     3601 atcatagcct gcctcctcta attttgtact attgtatcaa aaactgacaa agtgtcaagg
     3661 aggaaactga tgaactggac aaaaaacaag cctacatcgt cagctgccac agtggtttgc
     3721 gcagctatat cgcagagcct atcctcaagc aagcaggatt taccgcccaa aaccttgacg
     3781 gcgcttattc actatacaaa atggttaacc cagaaggagt agaatatgga aactagtatc
     3841 agcatggctg acttttatgg aaaataccaa aatgaaaatc tagaacttat cgatgtccgt
     3901 gaagcacatg aattccaagc aggacatgca ccaggtgcca aaaatcttcc attaagtacc
     3961 ttagagcaag gctacaaaga actcaaacct gaccatgaat actatgtcat ttgtcaagga
     4021 ggagtccgct ctgcatctac ctgccagttt ctcagctccc aaggcctcac cgttaccaac
     4081 gtagaaggtg gtatgaatgc ttggcccggt caagtagaat aatcaagagg agttgggcaa
     4141 aaactcaatt tcaggaaaag atgaagtaat actcaatgaa aatcaaagtg caaactagga
     4201 agttagccgc aggctgctca aaaca
//
LOCUS       DBEJHE010000066         3988 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC4 isolate 671759
            SAMN38261586-rid24793303.denovo.66, whole genome shotgun sequence.
ACCESSION   DBEJHE010000066 DBEJHE010000000
VERSION     DBEJHE010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261586
            Sequence Read Archive: SRR26833752
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 3988)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3988)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576136.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576136.1
            Genome Coverage       :: 109x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 19:48:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,067
            CDSs (total)                      :: 2,029
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 131
            CDSs (without protein)            :: 131
            Pseudo Genes (ambiguous residues) :: 0 of 131
            Pseudo Genes (frameshifted)       :: 64 of 131
            Pseudo Genes (incomplete)         :: 59 of 131
            Pseudo Genes (internal stop)      :: 46 of 131
            Pseudo Genes (multiple problems)  :: 32 of 131
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3988
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261586-rid24793303.denovo.66"
                     /strain="GPSC4"
                     /isolate="671759"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(<1..820)
                     /locus_tag="ACL3EZ_002025"
     CDS             complement(<1..820)
                     /locus_tag="ACL3EZ_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HGR0393531.1"
                     /translation="MLIGQKIKEIRIEKGISRPDFCGDEQELTVRQLSRIESGASQPS
                     LPKLAYIARRLGVPVYSLMPDFSALPSAYLELKYQILREPIYGKEEEYDKKEACLDTS
                     RTRRPEYAELILEEHMSQIIEKEVYSTNDMLLIRLFFYQMLIRKDLAKFINQIEKLML
                     FLLEQKKVTKLENFFIIRDTLISGMCCLEKVGVTDCFNDYLSCLQEIMDKTQDYQKKP
                     LVFMFLWKQALRVERDFSLAESFYQSSKTFAKLIGDGFLVKKLTEEWQEDVKKYL"
     gene            complement(892..1452)
                     /gene="rnmV"
                     /locus_tag="ACL3EZ_002026"
     CDS             complement(892..1452)
                     /gene="rnmV"
                     /locus_tag="ACL3EZ_002026"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043822 - ribonuclease M5 activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HGR0393532.1"
                     /translation="MKEKISQVIVVEGRYDTVNLKRYFDVETYETRGSAINDQDIERI
                     QRLHQRHGVIVFTDPDFNGERIRRMIMTAIPTVQHAFLKRDEAVPKSKTKGRSLGIEH
                     ASYEDLKTALAQVTEQFEHESQFDISRSDLIRLGFLAGADSRKRREYLGETLRIGYSN
                     GKQLLKRLELFGVTLAEVEEAMKSYE"
     gene            complement(1452..2225)
                     /locus_tag="ACL3EZ_002027"
     CDS             complement(1452..2225)
                     /locus_tag="ACL3EZ_002027"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HGR0393533.1"
                     /translation="MIFDTHTHLNVEEFAGREAEEIALAAEMGVIQMNIVGFDKPTIE
                     RALELVDEYEQLYATIGWHPTEAGTYTEEVEAYLLDKLKHSKVVALGEIGLDYHWMTA
                     PKEVQEQVFRRQIQLSKDLDLPFVVHTRDALEDTYEIIKSEGVGPRGGIMHSFSGTLE
                     WAEKFVDLGMTISFSGVVTFKKATDLQEAAKELPLDKMLVETDAPYLAPVPKRGRENK
                     TAYTRYVVDFIADLRGMTTEELAVATTANAERIFGLDSK"
     gene            complement(2530..3423)
                     /locus_tag="ACL3EZ_002028"
     CDS             complement(2530..3423)
                     /locus_tag="ACL3EZ_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000226469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall surface anchor protein"
                     /protein_id="HGR0393534.1"
                     /translation="MVAQDPKAQDSTKPTAEKSTVKAPAQRVDVKDITHLTDEEKVKV
                     AILQANGSALDGATINVGGDGTATITFPDGSVVTILGKDTVQQSAKGESVTQEATLEY
                     KLETIPGGDKGGNTGSSDANANEGGGSQAGGSAHTGSQNSAQSQASKQLATEKESAKN
                     AIEKAAKDKQDEIKGAPLSDKEKAELLARVEAEKQAALKEIENAKTMEDVKEAETIGV
                     QAIAMVTVPKRPVAPNAAPKTTSAPQATAGTMQDVTYQSPAGKQLPNTGSASSAALAS
                     LGLVVATSGFALLGRKTRRRK"
     gene            complement(3707..3841)
                     /gene="rpmH"
                     /locus_tag="ACL3EZ_002029"
     CDS             complement(3707..3841)
                     /gene="rpmH"
                     /locus_tag="ACL3EZ_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HGR0393535.1"
                     /translation="MKRTYQPSKLRRARKHGFRNRMSTKNGRRVLAARRRKGRKVLAA
                     "
BASE COUNT         1080 a          938 c          669 g         1301 t
ORIGIN      
        1 ataaatattt tttgacatcc tcttgccatt cctctgtcaa tttctttact agaaatccat
       61 ctccaattag cttcgcaaat gttttagaag actgataaaa tgattcagct aaactaaaat
      121 ctctttctac tcttaatgct tgcttccaca aaaacataaa tacaagaggt ttcttttgat
      181 aatcttgagt tttatccata atttcttgta aacacgatag ataatcatta aaacaatcag
      241 ttactcctac cttttcaaga caacacattc ctgaaataag agtatctcta attataaaga
      301 agttttctaa tttagttacc tttttctgtt ccaaaagaaa gagcattagc ttttcgattt
      361 gatttataaa tttggcaaga tcttttctaa tgagcatttg ataaaaaaac aaacgaatca
      421 acaacatatc atttgttgaa taaacttctt tttctatgat ctgagacata tgttcctcaa
      481 gtattaactc tgcatattca ggccttctag ttctagaagt atccaaacac gcttctttct
      541 tatcatactc ctcttcttta ccatagattg gttcacgtaa aatctggtat ttcaattcta
      601 aataagcaga aggaagagct gaaaaatccg gcataaggct ataaactgga actcctagcc
      661 ggcgagcaat ataggctaac ttgggcaaac tcggttgcga agctccactt tcaattcgcg
      721 acagttgacg aactgtcagt tcttgctcat ctccacaaaa atctggacga ctaattcctt
      781 tttctatccg aatctcttta attttttgac caattaacat cagacgcctc ctcttctacc
      841 tgcttcgaaa aatactgtga aacttaaaaa attgtaacgg ctacatcttt cctactcata
      901 agatttcata gcttcttcca cttctgccaa agtaacccca aacaactcta ggcgtttgag
      961 gagttgcttg ccattagaat agccgattcg gagagtctct ccgagatatt ctctacgctt
     1021 acggctgtct gcccctgcta gaaaaccaag gcgaatcaag tcgctacgac taatgtcaaa
     1081 ctgactctca tgttcaaatt gttctgtcac ctgagctaga gccgttttca ggtcttcata
     1141 gctggcatgc tcaattccca gagaacgccc cttggtcttg gacttgggaa cagcttcatc
     1201 tcgcttgaga aaggcatgct gaactgttgg aatggccgtc ataatcatgc gccgaatccg
     1261 ctccccatta aaatctgggt ctgtaaagac aatgactcca tgacgttggt gtagacgctg
     1321 aattcgctct atatcctgat cattgatggc agaacctcgt gtctcatagg tctccacatc
     1381 gaaataacgc ttgagattga ccgtatcata gcgaccttca accacgataa cttgagaaat
     1441 tttctctttc attacttgct gtccaatcca aaaattcgtt ctgcatttgc agtcgttgct
     1501 accgccagct cttctgtcgt cataccacgc aagtcagcga taaagtcgac cacatagcga
     1561 gtataggctg ttttattttc acgaccacgc ttgggtacag gtgctaagta aggcgcatct
     1621 gtttccacca acatcttgtc caaaggtaac tctttagctg cttcttggag gtcagttgcc
     1681 ttcttgaaag tcaccactcc tgagaaggaa atggtcatac caagatccac aaacttctct
     1741 gcccactcaa gcgtccctga aaatgaatgc atgataccac cacgaggacc aacgccctca
     1801 ctcttgataa tctcataggt atcttccagc gcatcacggg tatggacaac aaaaggcaaa
     1861 tccaagtcct tagatagctg aatctgacgg cgaaaaacct gctcctgcac ctctttgggc
     1921 gctgtcatcc aatggtagtc taagccaatt tcacctaaag ccacaacctt ggaatgtttt
     1981 aacttatcca acaagtaagc ctcaacttcc tctgtataag taccagcttc tgtaggatgc
     2041 caaccaatag tcgcatagag ctgctcatac tcatctacca actccaaggc acgctcaatc
     2101 gtcggtttat caaaaccaac aatattcatc tgtatcacac ccatctcagc agccaaggca
     2161 atttcttctg cctcacgacc tgcaaattct tctacattca agtgtgtatg tgtatcaaaa
     2221 atcatctctt ctaacctcgt tttctatctt ctattatacc aaaaaagagg aggggcacct
     2281 aatttttcgg tttcccctcc tctcttcaat agagagctat tctgctatct tttctatccg
     2341 atattgccca tctcctattc cacagttaga gacagaagag attggctaca ttgatagaat
     2401 attcctattc agctaaagta tgtgattatc ttgggttctc acttttctca cccatcacta
     2461 ggattgatga cttctcaaaa tcccccttat aatctaactt taagtagaga atagaatttt
     2521 ctagctgttc tattttctac gtctagtctt tcttcctagc aaagcaaaac cacttgttgc
     2581 caccactaga ccaagactag caagtgctgc acttgatgct gaacctgtgt taggtaattg
     2641 tttgccagca ggtgactggt aggtaacatc ttgcattgtt cctgcagttg cttgcggtgc
     2701 acttgttgtc ttaggagcag cattaggagc cactggtctc ttaggaactg taaccatggc
     2761 aatggcttgc actccaatcg tttctgcttc cttcacatct tccatagttt tcgcattttc
     2821 aatctctttg agagctgctt gtttttctgc ttccactctt gctaaaagtt ctgctttttc
     2881 tttatcagaa agcggtgcgc ctttgatttc atcctgctta tccttggctg ctttttcaat
     2941 ggcattttta gctgattctt tttcagtagc taattgctta gaagcttgtg attgagctga
     3001 gttttgtgaa cctgtgtgag ctgatccacc cgcctggcta ccaccgcctt cattcgcatt
     3061 agcatctgag cttccagtat tgcctccctt atctccacct ggtatagttt ctagcttata
     3121 ctctagtgta gcttcttgag ttacagattc acctttcgca gattgttgaa ctgtatcttt
     3181 tcctagaatc gtcactactg aaccatctgg gaatgtgatt gttgctgtac catctccacc
     3241 tacattgatt gtcgctccgt ctaatgctga accatttgct tgtaaaatag caaccttaac
     3301 tttttcttca tctgttaaat gagttatatc ttttacatct actctttgag caggtgcttt
     3361 aacagttgat ttttcagcag tcggtttagt gctatcttgt gcttttggat cttgtgctac
     3421 caattgattt cctggaattg taatagctga accatcttta aagacgattg ttgctgtacc
     3481 atctccacct acttcaactt tatagtaaaa taaaataata acaggacaaa tcgatcagga
     3541 cagtcaaatc gatttctaac aatgttttag aaacagaggt gtactattct agtttcaatc
     3601 tactataaca tcgcttccga atccatttgc atctactgaa cttttttaca aaaataaaaa
     3661 tcagtagact cgagttccta ctgatttttg atagaattcg tttggattat gcagccaaaa
     3721 ctttgcgtcc tttacgacga cgagctgcca atacgcgacg accattttta gttgacatac
     3781 ggttacggaa tccgtgttta cgcgcacgac gaagtttact tggttgataa gtacgtttca
     3841 cgatgaatac ctcctcatag attttgtatt cgtttagccg gctataaagt gatcagttac
     3901 taaacatact ttactattct atctgattct ttcacttttg tcaatagctc taggcaaatg
     3961 tttccagctt tttcgaatgc aagcccta
//
LOCUS       DBEJHE010000067         3471 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC4 isolate 671759
            SAMN38261586-rid24793303.denovo.67, whole genome shotgun sequence.
ACCESSION   DBEJHE010000067 DBEJHE010000000
VERSION     DBEJHE010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261586
            Sequence Read Archive: SRR26833752
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 3471)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3471)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576136.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576136.1
            Genome Coverage       :: 109x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 19:48:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,067
            CDSs (total)                      :: 2,029
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 131
            CDSs (without protein)            :: 131
            Pseudo Genes (ambiguous residues) :: 0 of 131
            Pseudo Genes (frameshifted)       :: 64 of 131
            Pseudo Genes (incomplete)         :: 59 of 131
            Pseudo Genes (internal stop)      :: 46 of 131
            Pseudo Genes (multiple problems)  :: 32 of 131
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3471
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261586-rid24793303.denovo.67"
                     /strain="GPSC4"
                     /isolate="671759"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            <1..335
                     /locus_tag="ACL3EZ_002030"
     CDS             <1..335
                     /locus_tag="ACL3EZ_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0393536.1"
                     /translation="HYRSYGTFFLHKNRLHNIHRGVTHYKYYRAENSHLIYADYFEMK
                     LQKLLKDDTKVFEKSTFKFVEGYKIYLTESKESGIKQMDNVIKYFEFIESKSIALYFQ
                     KRLNELID"
     gene            complement(693..1226)
                     /locus_tag="ACL3EZ_002031"
     CDS             complement(693..1226)
                     /locus_tag="ACL3EZ_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HGR0393537.1"
                     /translation="MKLPKEGDFITIQSYKHDGSLHRTWRDTMVLKTTENAIIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGTSYYCNMASPYYLDEEALKYI
                     DYDLDVKIFTDGEKRLLDVEEYERHKRKMNYSDDLDYILKEHVKILVDWINNGRGPFS
                     EAYVNIWYKRYVELKNR"
     gene            complement(1315..2091)
                     /gene="recX"
                     /locus_tag="ACL3EZ_002032"
     CDS             complement(1315..2091)
                     /gene="recX"
                     /locus_tag="ACL3EZ_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000705102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006282 - regulation of DNA repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HGR0393538.1"
                     /translation="MKITKLEKKKRLYLMELDNGDKCYITEDTIVRFMLSRDKVISEE
                     ELKEIQDFAQFSYGKNLALYHLSFKARTEKEVREYLKKYDIDKNIVSQVIANLKEDKW
                     INDGQYAYAIINTNQLSGDKGPYVLTQKLSQKGISKSTIEENLKEFDFSEVAQRVANK
                     LLKKYEGKLPARALQDKIIQNLTNKGFSYSDAKIAFDDLDSQVDQETTQELIFKELDK
                     QYTKYARKYEGYELKQRLTQVLARKGYDFSDIASALREYL"
     gene            2129..>3471
                     /gene="rlmD"
                     /locus_tag="ACL3EZ_002033"
     CDS             2129..>3471
                     /gene="rlmD"
                     /locus_tag="ACL3EZ_002033"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HGR0393539.1"
                     /translation="MNLKVKQKIPLKIKRMGINGEGIGFYQKTLVFVPGALKGEDIYC
                     QITSIRRNFVEAKLLKVNKKSKFRIVPSCTIYNECGGCQIMHLHYDKQLEFKTDLLHQ
                     ALKKFAPAGYENYEIRPTIGMQEPKYYRAKLQFQTRKFKNQVKAGLYAQNSHYLVELK
                     DCLVQDKETQVIANRLAELLTYHQIPITDERKVLGVRTIMVRRARKTGQVQIIIVTNR
                     QLNLTQLVKELVKDFPEVVTVAVNTNTAKTSEIYGEKTEIIWGQESIQEGVLNYEFSL
                     SPRAFYQLNPEQTEVLYSEAVKALDVDKEDHLIDAYCGVGTIGFAFAKKVKTLRGMDI
                     IPEAIEDAKRNAKRMGFDNTHYEAGTAEEIIPRWYKEGYRADALIVDPPRTGLDDKLL
                     DTILTYVPEKMVYISCNVSTLARDLVRLVEVYDLHYIQSVDMFPHTARTEAVVKL"
BASE COUNT         1131 a          590 c          608 g         1142 t
ORIGIN      
        1 ttcattatag gtcatatggg actttttttc tacacaaaaa taggctccat aatatccata
       61 ggggggttac ccactacaaa tattatagag ccgaaaattc acatctaata tatgcagact
      121 actttgaaat gaaattacaa aaattattaa aagatgacac aaaagttttt gaaaaatcta
      181 cattcaaatt tgtagaagga tataaaatat acctgacaga atctaaagaa tctggaatta
      241 aacaaatgga caatgtcata aaatattttg agtttattga atctaaaagt attgctttat
      301 attttcaaaa acgattaaat gagctgatag attaaatatc attttctctg ttaagatatt
      361 gtttttaaaa tattgtacta aatgattgat gctatgtgga aatacaaaaa aatgtttttg
      421 atacgaagtt gacctgtatt ttttatacta atcattttcg tattttttgt attaaacgat
      481 ataagtttgt tgtaaactta ctaggaataa agacattaaa aaataatagt atatctattt
      541 gttttatata ttttacgaat tctgcataaa tctctttcta gtaatgtgtt gtaactctgc
      601 tataatggat ttattccttt ttgtatttac acaatttatt ttatactacc aaaaaaacaa
      661 ggtcaggatt ttgttcctga cctttgacaa ctttaccgat tctttagttc tacatagcgc
      721 ttgtaccaaa tgtttacata ggcttctgag aaaggaccac gtccattgtt aatccaatca
      781 acaagaattt tgacatgttc ttttaaaata tagtccaagt catcagaata attcattttg
      841 cgtttgtgac gctcgtattc ttcaacgtcc aagagacgtt tttccccatc tgtaaaaatt
      901 ttaacatcca aatcgtaatc aatatacttc agtgcttctt catccagata gtaggggcta
      961 gccatattgc aatagtaaga agttccatta tcacgaatca tggcaatgat attaaaccaa
     1021 tatttcttgt gaaagtaaac aatagccggt tctcgagtga cccaacgacg accatcactt
     1081 tcggtaacaa gtgtatgatc gttgacacca ataatggcgt tttctgttgt ttttagtacc
     1141 atggtgtccc gccaagttcg gtggagactc ccatcatgct tataactttg aattgtaata
     1201 aagtcgcctt cttttggaag cttcataact aaccaacttt ctacaattta taagtttatc
     1261 atttactatt gtaccataaa attacctaaa atctgtgaat ttcacttgga aatattaaag
     1321 atattctcta agagcgcttg ctatatccga aaaatcgtag ccctttcgtg ctaaaacttg
     1381 agttaaacgc tgcttcagtt cgtatccttc atactttcga gcatacttag tatattgctt
     1441 atcaagttcc ttgaagatga gttcttgagt cgtttcttgg tcaacttggc tatctaagtc
     1501 gtcaaaggca attttagcat cagaataaga gaagcccttg ttagtcaagt tctggataat
     1561 cttatcttgc agggcacgag ctggaagttt tccctcatat tttttcaata gtttattggc
     1621 tacacgttga gcaacttcag aaaaatcaaa ttctttcaag ttctcttcta tagtagattt
     1681 tgaaatccct ttttgagata gtttctgagt cagcacataa ggacccttgt ctcctgaaag
     1741 ttgattggta ttgatgatag cataagcgta ctgaccatca ttaatccact tatcttcttt
     1801 aagattagca ataacttgag aaacgatgtt tttatcaata tcgtattttt tcagatattc
     1861 tctgacttct ttttcagtgc gtgctttaaa ggataagtgg tagagagcga gattcttacc
     1921 ataagaaaat tgagcaaagt cttgaatctc tttcaattcc tcttcgctta tcaccttatc
     1981 tctcgataac ataaaacgaa caattgtatc ttcggtgata tagcatttgt cgccattatc
     2041 aagctccatc aggtagagtc tttttttctt ttcaagtttt gtgattttca tagctctatt
     2101 ataactcaaa atgtgataag ataggggtat gaatctgaaa gtgaaacaaa aaataccatt
     2161 aaaaatcaag cgcatgggaa ttaacggtga gggaatcggc ttttaccaaa aaacattagt
     2221 ctttgtacca ggagctctca aaggcgaaga tatctattgt cagattactt ctattagacg
     2281 caactttgtt gaagcaaaat tactgaaggt caacaagaag tctaaatttc gaattgtgcc
     2341 atcttgtact atttataatg aatgcggagg ctgccaaatc atgcacctgc attatgataa
     2401 gcagctggag ttcaagacgg acttacttca tcaagcgctg aaaaaatttg ctcctgcagg
     2461 atatgaaaat tatgaaattc gtccaactat tggaatgcag gaaccaaaat attacagagc
     2521 taagttacaa tttcagactc gaaaatttaa aaatcaggtc aaggcgggct tatatgcaca
     2581 aaactctcac tatttagtag agttgaaaga ctgcctggta caagataagg aaacccaagt
     2641 gattgctaat cgcttagcag aattacttac ttatcaccag attccaatca cggatgagag
     2701 aaaagttcta ggtgtccgta ctattatggt ccgacgcgcg agaaagaccg gacaggttca
     2761 gattattatt gttacaaacc gccagcttaa tttaactcaa ttggtaaaag agttggttaa
     2821 agatttccca gaagttgtga cagtagctgt taatacaaat acagctaaaa ccagtgagat
     2881 atatggtgaa aagacagaga ttatctgggg gcaagagagt attcaagaag gtgtactcaa
     2941 ttatgaattt tcactatccc ctcgagcttt ttatcaacta aatcctgagc aaacagaagt
     3001 cctctatagc gaagcagtaa aagcgctgga tgttgataaa gaagaccatt tgattgacgc
     3061 ttattgtgga gttggaacga ttggatttgc ctttgcaaag aaagttaaaa cactcagagg
     3121 tatggatatt attccagaag ctattgaaga tgccaagcga aatgctaaaa gaatgggatt
     3181 tgacaatact cattatgaag ctggaacggc agaagagatt attcctcgtt ggtacaagga
     3241 aggctaccga gcagatgctt tgattgttga cccaccacgt acaggtctgg atgataagtt
     3301 attagatact attcttactt atgtaccaga aaaaatggtt tatatttctt gtaatgtttc
     3361 gaccttggct cgtgatttgg tacgcttagt agaagtctat gatcttcatt atatccagtc
     3421 ggtcgatatg ttcccacata cagctcgaac tgaagctgtt gtaaaattaa t
//
LOCUS       DBEJHE010000068         2791 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC4 isolate 671759
            SAMN38261586-rid24793303.denovo.68, whole genome shotgun sequence.
ACCESSION   DBEJHE010000068 DBEJHE010000000
VERSION     DBEJHE010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261586
            Sequence Read Archive: SRR26833752
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 2791)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2791)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576136.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576136.1
            Genome Coverage       :: 109x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 19:48:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,067
            CDSs (total)                      :: 2,029
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 131
            CDSs (without protein)            :: 131
            Pseudo Genes (ambiguous residues) :: 0 of 131
            Pseudo Genes (frameshifted)       :: 64 of 131
            Pseudo Genes (incomplete)         :: 59 of 131
            Pseudo Genes (internal stop)      :: 46 of 131
            Pseudo Genes (multiple problems)  :: 32 of 131
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2791
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261586-rid24793303.denovo.68"
                     /strain="GPSC4"
                     /isolate="671759"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            <1..821
                     /locus_tag="ACL3EZ_002034"
     CDS             <1..821
                     /locus_tag="ACL3EZ_002034"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HGR0393540.1"
                     /translation="EKVDEYAESYNRLEQLDKEFPDKLKKSILQYAMQGKLVEQDPND
                     ESVEVLLEKIRAEKQKLFEEGKIKKKDLDISIVSQGDDNSYYEEVPCEIPESWEWVRL
                     NDITSYIQRGKSPKYSNIPIYPVIAQKCNQWSGFSIDLARFIDPETVHSYQKERLLRD
                     GDLMWNSTGLGTLGRLAIYHENKNPYVWAVADSHVTVIRVLSGVINCHFIYNFLSSPI
                     VQSVIEEKASGSTKQKELLTKTIKEYLIPLPPLPEQSRIVDKIEQFFAHIDALI"
     gene            878..1675
                     /gene="psrA"
                     /locus_tag="ACL3EZ_002035"
     CDS             878..1675
                     /gene="psrA"
                     /locus_tag="ACL3EZ_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type DNA invertase PsrA"
                     /protein_id="HGR0393541.1"
                     /translation="MKDFELHLKKAGLAENTVRSYLYGVRFFLENYELKMEDLFEYKG
                     YLLDNFKPKTVNLRLQGVNKYLAFIGHDDLKLKFVKVQQKPFLEDVISHADYLFLKRS
                     LKKDGILKWHFVVWFLGATGARVSELIKLKVEHVEIGYFDIYSKGGKIRRLYIPKKLR
                     NSCLSWLESENRRSGYLFLNKFNEPITARGVAQQLKNYADKYKMNPKVIYPHSFRHLF
                     AKNFLAKYNDIALLADLMGHESIETTRIYLRKTATEQQNIVDKIVNW"
     gene            1746..2285
                     /locus_tag="ACL3EZ_002036"
     CDS             1746..2285
                     /locus_tag="ACL3EZ_002036"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HGR0393542.1"
                     /translation="MNWVVIKIKDIFSMNTGLSYKKGDLSINNKGVRIIRGGNIKPLE
                     FSLLDNDYYIDTQFISSEQVYLKHNQLITPVATSLEHIGKFARIDKDYDGVVAGGFIF
                     QLTPFESSEIISKFLLFNLSSPLFYKQLKAITKLSGQALYNIPKTTLSELLIPLAPFE
                     EQELITQKVEKLFEKVNQL"
     gene            complement(2239..>2791)
                     /locus_tag="ACL3EZ_002037"
     CDS             complement(2239..>2791)
                     /locus_tag="ACL3EZ_002037"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HGR0393543.1"
                     /translation="DETTSYPIYEIPEAWRYIKFASLVNFRIGKTPPRSEATFWGTEI
                     PWVSISDMPISGYVTNTRESISKLALKSKKIDISPKGTLLMSFKLSIGKVAILDIPAT
                     HNEAIISIFPYANKENIIRDYLMIFLPLISTLGDSKDAIKGKTLNSTSISELLIPISN
                     HEEMKRIIFKVDLLFQKVSQLFE"
BASE COUNT          983 a          395 c          481 g          932 t
ORIGIN      
        1 tagaaaaagt agatgaatat gctgaaagtt ataatagact agaacagcta gataaagaat
       61 ttccagataa actaaaaaaa tctattcttc aatatgctat gcaaggaaaa ttagttgaac
      121 aagacccaaa tgatgaatca gtcgaagttt tacttgaaaa aatacgagca gaaaaacaaa
      181 aactctttga agaaggcaag attaaaaaga aagatttgga catttctatt gtttcccaag
      241 gagatgataa ctcttattat gaggaagtac cttgtgaaat accagaaagt tgggaatggg
      301 tgaggttaaa cgatataacc tcctacattc aaagagggaa gtctccaaaa tattcaaata
      361 ttcctatata ccctgtgatt gctcagaaat gtaatcaatg gtctggcttt tctattgact
      421 tagcaagatt tattgatccc gaaacagttc atagttacca gaaagaaaga ttactaagag
      481 atggtgattt aatgtggaat tcaacaggtc taggtacgtt aggacgatta gctatttacc
      541 atgaaaataa aaatccttat gtctgggctg ttgcagatag ccatgttaca gttataagag
      601 tcttatcggg agttattaat tgccatttca tctataattt tctttcctct cctattgttc
      661 agtcagttat tgaagaaaaa gcgtcgggta gtacaaaaca aaaagaatta ttaacgaaaa
      721 ctataaaaga atatttaatc cccctcccac cccttcctga acaatccaga atcgttgata
      781 aaatcgaaca atttttcgcc catattgacg cactaattta gtataatagt tttacgtgcg
      841 gtggaatttc tatcaaacat aagataggag ttttacgttg aaagattttg aattacattt
      901 gaagaaagct ggtttagctg aaaatactgt gcgttcgtac ctttatggtg ttcgattttt
      961 cttggagaat tacgaactca aaatggaaga tttatttgaa tacaaaggat atttattaga
     1021 caattttaaa cctaaaactg tcaatttgcg actacaagga gtaaataaat atctggcttt
     1081 tattggtcat gatgatttga aattaaaatt tgtcaaagta cagcaaaaac cgtttttaga
     1141 agatgtcatt agccatgctg attacctttt tcttaaacgt agtttgaaaa aagatggtat
     1201 tttaaaatgg cattttgtcg tttggttttt aggtgcaact ggggctcgtg taagtgaact
     1261 tattaaacta aaagtagagc atgtagaaat cggttatttt gacatttact caaaaggtgg
     1321 taaaattcgt agactgtaca ttcctaaaaa attaagaaat agttgtctta gttggttaga
     1381 atcagaaaat cgccgaagtg gttatttatt tttgaataaa tttaacgaac caattacagc
     1441 aagaggagtt gctcaacagt taaaaaatta tgctgataaa tacaaaatga atcctaaagt
     1501 aatttaccct cattctttta ggcatttatt tgctaagaat tttttagcga agtataatga
     1561 tattgccttg cttgcagatt tgatgggaca cgaaagtata gaaactactc gaatttatct
     1621 aaggaaaaca gctactgaac aacaaaatat tgtagataaa attgttaatt ggtaaaaaat
     1681 aacaggtggt caaactgact acctgctatt tttgtgatta tggctcttat tatgggaata
     1741 tacctatgaa ttgggttgtt ataaaaataa aagatatttt ttcaatgaat acaggtcttt
     1801 cttacaagaa gggcgattta agcattaata ataaaggtgt tagaattata cgtggtggta
     1861 atattaagcc tttagaattt tctctgttgg ataatgatta ctacattgat acacaattca
     1921 tctcctctga gcaagtttat ttaaaacata atcagctaat aacacctgta gcaacctctt
     1981 tagaacatat tggaaagttt gcaagaatcg ataaagacta tgatggtgtt gtggctggtg
     2041 gatttatttt ccaattaaca ccattcgaaa gttcagagat tatttcaaaa tttctattat
     2101 ttaacttgtc ctctccgtta ttttataaac aattgaaagc aataactaaa ctatcaggtc
     2161 aagctttata taatattcct aaaactacac tgagcgagct attaattccg ttagctcctt
     2221 ttgaggaaca ggaacttatt actcaaaaag ttgagaaact ttttgaaaaa gtaaatcaac
     2281 tttgaaaatg attcttttca tctcttcatg attagaaata gggattaata attcggagat
     2341 actggtacta tttaatgttt tccctttgat agcatctttt gaatcaccta aagtagagat
     2401 aagtggcaaa aatatcatta agtaatctct gataatattt tctttattag cataggggaa
     2461 tatcgatata atggcttcat tatgagtggc aggaatatcc aatatggcaa cttttccaat
     2521 agataattta aaactcatta ataaagttcc tttaggtgaa atgtctattt tctttgattt
     2581 taatgctaat ttagaaatag attctctcgt attagttaca taaccagata taggcatatc
     2641 tgatatagat acccaaggta tttcagttcc ccaaaaagta gcttcactgc gtggaggagt
     2701 ttttcctatt ctgaagttaa ctaggctagc aaatttaata tatctccatg cttctgggat
     2761 ttcatatata ggataagagg ttgtttcgtc t
//
LOCUS       DBEJHE010000069         2535 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC4 isolate 671759
            SAMN38261586-rid24793303.denovo.69, whole genome shotgun sequence.
ACCESSION   DBEJHE010000069 DBEJHE010000000
VERSION     DBEJHE010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261586
            Sequence Read Archive: SRR26833752
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 2535)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2535)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576136.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576136.1
            Genome Coverage       :: 109x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 19:48:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,067
            CDSs (total)                      :: 2,029
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 131
            CDSs (without protein)            :: 131
            Pseudo Genes (ambiguous residues) :: 0 of 131
            Pseudo Genes (frameshifted)       :: 64 of 131
            Pseudo Genes (incomplete)         :: 59 of 131
            Pseudo Genes (internal stop)      :: 46 of 131
            Pseudo Genes (multiple problems)  :: 32 of 131
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2535
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261586-rid24793303.denovo.69"
                     /strain="GPSC4"
                     /isolate="671759"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            150..1103
                     /locus_tag="ACL3EZ_002038"
     CDS             150..1103
                     /locus_tag="ACL3EZ_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS30-like element ISSpn8 family transposase"
                     /protein_id="HGR0393544.1"
                     /translation="MQEHYTPKGKHLTIDNRRLIERWKNENKSNREIAGLLGKAPQTI
                     HNEVKRGTTLQQVRKGLYKKVYSADYAQTVYQFNRKRSVKKLILTKEIREKILHYHKQ
                     KFSPEMMVNKKQVKVGISTIYYWFHNGHLGLTKADMLYPRKRKGVKKQASPNFKPAGK
                     SIEERPDVINLRLENGHYEIDTVLLTKIKNYCLLVLTDRRSRHQIIRLIPNKTAESVN
                     QALTLLLGEHRILSITADNGSEFKRLSEVFPEEHIYYAHAYSSWERGSNENHNRLIRR
                     WLPKGTKKTTPKEVAFIENWINNYPKKCLDYKSPSEFLLGG"
     gene            1267..2463
                     /gene="tuf"
                     /locus_tag="ACL3EZ_002039"
     CDS             1267..2463
                     /gene="tuf"
                     /locus_tag="ACL3EZ_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HGR0393545.1"
                     /translation="MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSV
                     NQPKDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQM
                     DGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDL
                     LSEYDFPGDDLPVIQGSALKALEGDSKYEDIVMELMNTVDEYIPEPERDTDKPLLLPV
                     EDVFSITGRGTVASGRIDRGIVKVNDEIEIVGIKEETQKAVVTGVEMFRKQLDEGLAG
                     DNVGVLLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILTKEEGGRHTPFFNNYRPQ
                     FYFRTTDVTGSIELPAGTEMVMPGDNVTIDVELIHPIAVEQGTTFSIREGGRTVGSGM
                     VTEIEA"
BASE COUNT          837 a          504 c          521 g          673 t
ORIGIN      
        1 ctaggtggcc aaggctaatc atagccttgg tttagctgaa aaaacaggtt caagggttcc
       61 tgttgtcaaa tgaaatgtga tttaaggtat aagaaaacac ctctgtgcta tacttgttgt
      121 tcaccacaaa cacaaggaaa ggcacagaga tgcaagaaca ttatacccca aaagggaaac
      181 atttgacaat agataaccgt cgcttgattg agcggtggaa gaatgaaaat aagtccaatc
      241 gtgaaattgc aggcttgtta ggaaaggcgc ctcaaacgat tcataatgaa gtcaaaagag
      301 gtacaacttt acaacaagtg agaaaagggc tatacaaaaa ggtctattct gccgattacg
      361 cacaaactgt ttaccaattc aatcgaaaac ggtcggtgaa aaagttaatt ttaacaaagg
      421 aaatcagaga gaagatctta cactatcata agcaaaaatt ttcgcctgaa atgatggtta
      481 acaagaagca agtgaaagtt ggtatttcaa ccatctacta ctggtttcat aatggtcatt
      541 taggattgac gaaggccgac atgctttatc ccagaaaaag gaaaggtgtc aagaagcaag
      601 ctagtccgaa ctttaagccg gcaggtaaat ctatcgaaga acgtcctgac gttattaatc
      661 ttcgcttgga aaatggtcat tatgaaattg ataccgtcct actaactaag ataaaaaatt
      721 attgcctgtt agtcttaacc gaccggcgga gcagacacca aattataagg ttaattccaa
      781 ataaaactgc tgaatctgtc aatcaggcgc ttacgttact attaggggag catcgtattc
      841 tgtccattac tgcagataat ggttcggagt tcaaacgatt gtctgaggta tttcctgagg
      901 aacatatcta ctacgcacat gcttactctt catgggagag aggttcaaat gaaaatcata
      961 atcgattaat tcggagatgg ttacctaaag gaaccaagaa aacgactccg aaagaagtag
     1021 cttttatcga aaattggatt aacaactacc ctaaaaaatg cttggactac aagtcgccaa
     1081 gtgaatttct tttgggtggc taacttcaac ttgaaatttg gggttaaatt tttaccaaga
     1141 ataattcaca aaaacgttgt aaaacacttg caatttagct gaaatttgat aaaatagtaa
     1201 ggaaagttag actgtattgc ctactgtcta tctataaaat atattttatt ggaggctttt
     1261 actcaaatgg caaaagaaaa atacgatcgt agtaaaccac acgttaacat tggtactatc
     1321 ggacacgttg accacggtaa aactacccta actgcagcta tcacaactgt tttggcacgt
     1381 cgcttgcctt catcagttaa ccaacctaaa gactatgcgt ctatcgatgc tgctccagaa
     1441 gaacgcgaac gcggtatcac tatcaacact gcgcacgttg agtacgaaac tgaaaaacgt
     1501 cactacgctc acatcgacgc tccaggacac gcggactacg ttaaaaacat gatcactggt
     1561 gctgctcaaa tggacggagc tatccttgta gtagcttcaa ctgacggacc aatgccacaa
     1621 actcgtgagc acatccttct ttcacgtcag gttggtgtta aacaccttat cgtcttcatg
     1681 aacaaagttg acttggttga cgacgaagaa ttgcttgaat tggttgaaat ggaaatccgt
     1741 gacctattgt cagaatacga cttcccaggt gacgatcttc cagttatcca aggttcagca
     1801 cttaaagctc ttgaaggtga ctctaaatac gaagacatcg ttatggaatt gatgaacaca
     1861 gttgatgagt atatcccaga accagaacgt gacactgaca aaccattgct tcttccagtc
     1921 gaggacgtat tctcaatcac tggacgtggt acagttgctt caggacgtat cgaccgtggt
     1981 atcgttaaag tcaacgacga aatcgaaatc gttggtatca aagaagaaac tcaaaaagca
     2041 gttgttactg gtgttgaaat gttccgtaaa caacttgacg aaggtcttgc tggagataac
     2101 gtaggtgtcc ttcttcgtgg tgttcaacgt gatgaaatcg aacgtggaca agttatcgct
     2161 aaaccaggtt caatcaatcc acacactaaa ttcaaaggtg aagtctacat ccttactaaa
     2221 gaagaaggtg gacgtcacac tccattcttc aacaactacc gtccacaatt ctacttccgt
     2281 actactgacg ttacaggttc aatcgaactt ccagcaggta ctgaaatggt aatgcctggt
     2341 gataacgtga caatcgacgt tgagttgatt catccaatcg ccgtagaaca aggtactaca
     2401 ttctctatcc gtgagggtgg acgtactgtt ggttcaggta tggttacaga aatcgaagct
     2461 taattcgatt tagttcccag aagaacaatt atttaagtca gacactaaaa gaatcttgct
     2521 tggcaaggtt ctttt
//
LOCUS       DBEJHE010000070         2346 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC4 isolate 671759
            SAMN38261586-rid24793303.denovo.70, whole genome shotgun sequence.
ACCESSION   DBEJHE010000070 DBEJHE010000000
VERSION     DBEJHE010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261586
            Sequence Read Archive: SRR26833752
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 2346)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2346)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576136.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576136.1
            Genome Coverage       :: 109x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 19:48:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,067
            CDSs (total)                      :: 2,029
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 131
            CDSs (without protein)            :: 131
            Pseudo Genes (ambiguous residues) :: 0 of 131
            Pseudo Genes (frameshifted)       :: 64 of 131
            Pseudo Genes (incomplete)         :: 59 of 131
            Pseudo Genes (internal stop)      :: 46 of 131
            Pseudo Genes (multiple problems)  :: 32 of 131
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2346
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261586-rid24793303.denovo.70"
                     /strain="GPSC4"
                     /isolate="671759"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            30..155
                     /locus_tag="ACL3EZ_002040"
                     /pseudo
     CDS             30..155
                     /locus_tag="ACL3EZ_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812181.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(127..1602)
                     /locus_tag="ACL3EZ_002041"
     CDS             complement(127..1602)
                     /locus_tag="ACL3EZ_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000661022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HGR0393546.1"
                     /translation="MKELDQNQAPIYEALVKLRKKRIVPFDVPGHKRGRGNPELVELL
                     GEKCVGIDVNSMKPLDNLGHPISIIRDAEELAADAFGASHAFLMIGGTTSSVQTMILA
                     TCKAGDKIILPRNVHKSAINALVLCGAIPIYIEMSVDPKIGIALGLENDRVAQAIKDH
                     PDAKAILINNPTYYGICSDLKGLTEMAHEAGMMVLVDEAHGAHLHFTGKLPISAMDAG
                     ADMAAVSMHKSGGSLTQSSLLLIGEQMNSEYVRQIINLTQSTSASYLLMASLDISRRN
                     LALRGKESFEKVIELSEYARREINAIGGYYAYSKELIDGVSVCDFDVTKLSVYTQGIG
                     LTGIEVYDLLRDEYDIQIEFGDIGNILAYISIGDRIQDIERLVGALADIKRLYSRDGK
                     DLIAGEYIQPELVLSPQEAFYSERKSLTLDESVGQVCGEFVMCYPPGIPILAPGERIT
                     REIVDYIQFAKERGCSLQGTEDPEVNHINVIKRKTNYKKSQ"
BASE COUNT          702 a          515 c          427 g          702 t
ORIGIN      
        1 ttgaggcagg atttgataag ctgatagaaa ttaagcgatt gaccgcttct aattcaaggg
       61 ctttttgccg tgctctaaaa tcatcgccaa atcatcaaat tgaaataaga aatagtttag
      121 ataaaactat tgacttttct tatagtttgt ctttctctta ataacgttga tatgattgac
      181 ctctggatct tccgtccctt ggagggagca accacgttcc ttggcgaatt ggatatagtc
      241 tacaatttct cgtgtaatgc gttcaccagg agccaagata ggaatccctg gaggatagca
      301 catgacaaat tctccacaga cctgtccaac agactcatct aaggtcaaac tttttctctc
      361 tgaatagaag gcttcttgtg gagacagcac caactcgggc tgaatatatt ctcctgctat
      421 caaatctttt ccatctcttg aatagagtct cttaatatca gccagagcac caaccaagcg
      481 ctcgatgtct tggatgcggt cgccgatgga aatataggcc aagatattgc cgatatcacc
      541 aaactcgatc tgaatgtcgt attcgtctcg caagaggtca taaacctcga tacctgttaa
      601 gccaataccc tgagtgtaaa ctgacagctt agttacgtca aaatcgcaaa ccgaaacacc
      661 gtctattaac tcttttgagt aggcatagta gccaccgata gcattgattt cacggcgggc
      721 atactcagat agctcaatga ctttctcaaa cgactcttta ccacgaaggg ccaagttgcg
      781 acgtgaaata tccaaactag ccatcaacaa gtaagaggca gatgtagact gagtcaggtt
      841 aattatctga cgaacgtatt cagaattcat ctgctccccg attaaaagaa gcgaactttg
      901 tgtcaaactc ccaccagact tatgcatgga aactgctgcc atatcagctc ctgcatccat
      961 agcagaaatt ggaagtttac cagtgaaatg caaatgcgct ccatgggctt catctactaa
     1021 aaccatcatg ccagcttcat gagccatttc tgtcaacccc tttaggtctg aacagatgcc
     1081 gtagtaagta ggattgttga ttaggatagc cttagcatct ggatggtcct ttatggcctg
     1141 tgctactcgg tcattttcaa gacctaaagc gataccaatc ttaggatcta cactcatctc
     1201 gatatagatg ggaatggcac cacatagaac caacgcattg atagcagatt tatggacatt
     1261 tcgtggcaga ataatcttat ctcctgcctt gcaggttgcc agaatcatag tctgcaccga
     1321 tgaagttgtt ccaccaatca ttagaaaggc atggctagct ccaaaagcat ctgcagccag
     1381 ctcctctgca tcacgaataa tcgaaatagg atggcctaaa ttatccaagg gtttcatcga
     1441 attgacatca atgcctacac atttttctcc taagagttcg acaagttctg gatttccccg
     1501 tccacgcttg tgacctggaa catcaaaggg aacaatcctt ttcttgcgta acttcaccaa
     1561 ggcctcataa attggggctt ggttttgatc taactctttc aaaacatact cctttcaata
     1621 tttttaggac cttatgaaaa ctaaggaact aaaggttgac tcatgaaaaa agagcaggtt
     1681 ttcacctgct ctgcaatctt ctgacgtgtt tattttggtt tctgttgagt atgtctgttc
     1741 ccgatgtttc ctaactctct agtagcaaat attacgtact ttattgatcg tttcacaaga
     1801 tgacgtgtgc tttcaccaca ctaaaaattt atgaattagg acaagtgtcc taacatcaac
     1861 ttataaaagt aggcttttaa ccctatcaat aatgtggctt ttcaaccacg cttcggcatt
     1921 caaccctgcc tgtccgtagg cattttttac tcgggtttat atttgctaga aaacatcatc
     1981 tcattttcta agctttatta ctatatcatg tttttaagaa cttgtaaagt attttttgat
     2041 aaaaaacaaa aatatagtag attgaaacta gaatagtaca cctctgcttc taaaacattg
     2101 ttagaaatag attttactgt cctgatcgat ttgttctgtt cttgtttcat tttactatat
     2161 gttcgtaaat gaaagttcta taatgaagtt agccacccag ccctcctaaa aattagatgg
     2221 ttcaactagc tgatagctct tgtaggcata agaaaacacc tctgtgttat acttgttgtt
     2281 caaccacaaa cacaagaaag gcacagagat gcaagacaat tatactacaa aagccaaaca
     2341 tttgac
//
LOCUS       DBEJHE010000071         2338 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC4 isolate 671759
            SAMN38261586-rid24793303.denovo.71, whole genome shotgun sequence.
ACCESSION   DBEJHE010000071 DBEJHE010000000
VERSION     DBEJHE010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261586
            Sequence Read Archive: SRR26833752
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 2338)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2338)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576136.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576136.1
            Genome Coverage       :: 109x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 19:48:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,067
            CDSs (total)                      :: 2,029
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 131
            CDSs (without protein)            :: 131
            Pseudo Genes (ambiguous residues) :: 0 of 131
            Pseudo Genes (frameshifted)       :: 64 of 131
            Pseudo Genes (incomplete)         :: 59 of 131
            Pseudo Genes (internal stop)      :: 46 of 131
            Pseudo Genes (multiple problems)  :: 32 of 131
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2338
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261586-rid24793303.denovo.71"
                     /strain="GPSC4"
                     /isolate="671759"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(1..247)
                     /locus_tag="ACL3EZ_002042"
                     /pseudo
     CDS             complement(1..247)
                     /locus_tag="ACL3EZ_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            588..1934
                     /gene="gdhA"
                     /locus_tag="ACL3EZ_002043"
     CDS             588..1934
                     /gene="gdhA"
                     /locus_tag="ACL3EZ_002043"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016639 - oxidoreductase activity, acting
                     on the CH-NH2 group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HGR0393547.1"
                     /translation="MTSAKEYIQSVFETVKARNGHEAEFLQAVEEFFNTLEPVFEKHP
                     EYIEENILARITEPERVVSFRVPWVDRDGKIQVNRGYRVQFNSAVGPYKGGLRFHPTV
                     NQGILKFLGFEQIFKNVLTGLPIGGGKGGSDFNPKGKTDAEVMRFCQSFMTELQKHIG
                     PSLDVPAGDIGVGGREIGYLYGQYKRLNQFDAGVLTGKPLGFGGSLIRPEATGYGLVY
                     YTEEMLKANGNSFAGKKVVISGSGNVAQYALQKATELGATVISVSDSNGYVIDENGID
                     FDLLVDVKEKRRARLTEYAAEKATATYHEGTVWTYAGNYDIALPCATQNEINGEAAKR
                     LVAQGVICVSEGANMPSDLDAIKVYKENGIFYGPAKAANAGGVAVSALEMSQNSLRLS
                     WTREEVDGRLKDIMTNIFNTAKTTSETYGLDKDYLAGANIAAFENVANAMIVQGIV"
BASE COUNT          741 a          414 c          435 g          748 t
ORIGIN      
        1 aaatcgttgt ttgattacag tctaaaagct ctataatctc tttataagat ttgcccatca
       61 gacgaaatat agtagattga aactagaata gtacacctct acttctaaaa cattgttaga
      121 aatcgatttg tcctgttctt gtttcatttt actatagaac gatttgaagg cgtttataat
      181 atttagctgt acgagagtct tttaaaagtg ttttgatggt ttggatttct tctttagttg
      241 atttcatatt actattatat aatgcttttt gattttagtc tggtataaat attgctttcc
      301 tccaaaatgg tcatagtttt actggcaaat ctaacatatc acggataaat taacaagtga
      361 tttctgaatt actaaacatt ttcttttctt atagcatacc atactttaag attttgtctt
      421 taagaaagat atttccaaga aaaacgttcg tttttttatc tattttcaaa aaaaccaaaa
      481 actgaattga aagaattttt agaaaatttc tgttttttct ttacagtgaa aaaaaattct
      541 gctataatgt cttatgtaat aaaatatgac aataaaagga gaacgatatg acatctgcta
      601 aagaatatat ccaaagcgtg tttgaaactg tgaaagctcg taacgggcac gaggctgaat
      661 tcctccaagc tgttgaagaa tttttcaaca ctttagaacc tgtatttgaa aaacaccctg
      721 agtatatcga agaaaatatc ttggcacgta ttactgagcc tgagcgcgtg gtttctttcc
      781 gtgttccttg ggttgaccgt gatggaaaaa ttcaagtaaa ccgtggttac cgtgttcaat
      841 tcaactcagc tgttggacca tacaaaggtg gacttcgttt ccacccaact gtaaaccaag
      901 ggatcttgaa attcctcgga tttgaacaaa tctttaaaaa tgtcttgact ggacttccta
      961 tcggtggagg taaaggtgga tcagacttca atcctaaagg taaaacagat gctgaagtga
     1021 tgcgcttctg ccaaagcttc atgactgaat tgcaaaaaca catcggacca tcacttgacg
     1081 tacctgctgg tgatatcggt gttggtggac gtgagattgg ttacctttac ggtcaataca
     1141 aacgtcttaa ccaatttgat gctggtgtct tgactggtaa acctcttgga tttggtggta
     1201 gcttgattcg tccagaagca actggttacg gtttggttta ctatactgaa gaaatgctca
     1261 aagctaacgg taacagcttt gctggtaaga aagtcgttat ttcaggttct ggtaacgttg
     1321 ctcaatatgc tcttcaaaaa gcaactgaac tcggtgcaac tgttatttct gtttctgact
     1381 caaatggtta tgtcatcgat gaaaatggta tcgacttcga tcttttggtt gatgttaaag
     1441 aaaaacgtcg tgctcgtttg actgagtatg cagctgaaaa agcaactgca acctaccacg
     1501 aaggtactgt atggacttac gctggaaact atgacattgc tcttccatgt gccactcaaa
     1561 acgaaatcaa cggtgaagca gctaaacgtt tggttgctca aggcgttatc tgtgtatctg
     1621 aaggtgccaa catgccaagc gaccttgatg ccatcaaagt ttacaaagaa aatggtatct
     1681 tctacggacc tgcaaaagct gccaacgctg gtggtgtagc cgtttcagct cttgaaatga
     1741 gccaaaacag tcttcgcctc tcatggactc gtgaagaagt tgatggccgt ctcaaagaca
     1801 tcatgacaaa catcttcaac acagctaaaa cgacttcaga aacatacggt cttgataaag
     1861 actaccttgc aggagctaac attgctgcct ttgaaaatgt agcaaatgcc atgattgtac
     1921 aaggtattgt ttaagattta tttactcaat cctcaatcac tacgattggg gatttttagc
     1981 ttgaattaaa aaattggaaa atctaattaa ataaaatgaa atgcaataaa aactgaacaa
     2041 attgattgcg gaattcaaac caatttctaa catatttcta gaaattaatt tgacttttct
     2101 aatcgatttg ttcatatctt atttcaattt actatactta cttaaccctt tttatactca
     2161 atgaaaatca aagagcaaac taggaagcga gccgcaggct gtacttgatt acggcaaggc
     2221 aaagctgacg tggtttgaag agattttcaa agagtattaa acaaaaagaa aaaccgctac
     2281 tcctaagaat agcgatttaa tcatgttttt aagctactac tgtagttgct ctattatt
//
LOCUS       DBEJHE010000072         2158 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC4 isolate 671759
            SAMN38261586-rid24793303.denovo.72, whole genome shotgun sequence.
ACCESSION   DBEJHE010000072 DBEJHE010000000
VERSION     DBEJHE010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261586
            Sequence Read Archive: SRR26833752
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 2158)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2158)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576136.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576136.1
            Genome Coverage       :: 109x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 19:48:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,067
            CDSs (total)                      :: 2,029
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 131
            CDSs (without protein)            :: 131
            Pseudo Genes (ambiguous residues) :: 0 of 131
            Pseudo Genes (frameshifted)       :: 64 of 131
            Pseudo Genes (incomplete)         :: 59 of 131
            Pseudo Genes (internal stop)      :: 46 of 131
            Pseudo Genes (multiple problems)  :: 32 of 131
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2158
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261586-rid24793303.denovo.72"
                     /strain="GPSC4"
                     /isolate="671759"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            96..634
                     /locus_tag="ACL3EZ_002044"
                     /pseudo
     CDS             96..634
                     /locus_tag="ACL3EZ_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399595.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
     gene            701..1111
                     /locus_tag="ACL3EZ_002045"
     CDS             701..1111
                     /locus_tag="ACL3EZ_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 2"
                     /protein_id="HGR0393548.1"
                     /translation="MYYLPVDFYRYLIGREDQSVNEQVMIKCIDQQLKVNRLLVDQLD
                     LSQVSHPKMREYLLNHIEITTVISSTLLNRSETAEHLAKKRQLWTYIQQKNPEVFQAI
                     RKTMLSRLTKHSVLPDRKLSNVVYQITKSVYGFN"
     gene            1227..>2158
                     /gene="pavB"
                     /locus_tag="ACL3EZ_002046"
     CDS             1227..>2158
                     /gene="pavB"
                     /locus_tag="ACL3EZ_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat adhesin PavB"
                     /protein_id="HGR0393549.1"
                     /translation="MKFNPNQRYTRWSIRRLSVGVASVVVASGFFVLVGQPSSVRADV
                     VNPTPGQVLPEETSGTKEGDLSEKPGDTVLTQAKPEGVTGNTNSLPTPTERTEVSEET
                     NSSSLDTLFEKDEEAQKNPELTDVLKETVDTADVDGTQASLAETTPEQVKGGVKENTK
                     DSIDVPAAYLEKAEGKGPFTAGVNQVIPYELFAGDGMLTRLLLKASDNAPWSDNGTAK
                     NPALPPLEGLTKGKYFYEVDLNGNTVGKQGQALIDQLRANGTQTYKATVKVYGNKDGK
                     ADLTNLVATKNVDININGLVAKETVEKAVKDNVK"
BASE COUNT          664 a          409 c          479 g          606 t
ORIGIN      
        1 agtcagtaac atctatacgg caaggcgacg ttgacgcggt ttgaagagat tttcgaagag
       61 tataagaaaa aatcagttcc ctaaaggagc agattatgaa gttattgtct atcgctattt
      121 ctagctataa tgcagcagcc tatcttcatt actgtgtgga gtcgctagtg attggtggtg
      181 agcaagttgg gattttgatt atcaatgacg ggtctcagga ccagactcag gaaatcgctg
      241 agtgtttagc tagcaagtat cctaatatcg ttagagccat ctatcaggaa aataaaggac
      301 atggcggtgt ggtcaatcgc ggcttggcag aggcttctgg gcgctatttt aaagtagttg
      361 acagtgatga ctggtggatc ctcgtgccta cttgaaaatt cttgaaacct tgcaggaact
      421 tgagagcaag ggtcaagaga tggatgtctt tgtgaccaat tttgtctatg aaaaggaagg
      481 tcagtctcgt aagaagagta tgagttacga gtcagtcttg cctgttcggc agatttttgg
      541 ctgggaccag gtcggaaatt tctccaaagg ccagtatatc atgatgcact cgctgattta
      601 tcggacagct ttgttgcgtg ctagccagtt ctaactgcct gaacatactt tttatgtcga
      661 taatctcttt gtctttacgc cccttcagca ggtcaagacc atgtactatc tgcctgtcga
      721 tttctatcgt tatttgattg ggcgtgagga ccagtctgtc aatgagcaag tgatgattaa
      781 gtgcattgac cagcaactca aggtcaatcg actcttggta gaccagcttg atttgtccca
      841 agtgagtcat cccaaaatgc gagaatatct gctgaatcat attgaaatca cgacggtgat
      901 ttccagtacc ctgctcaacc gatctgaaac agcggagcat ctggcaaaaa aacgccaatt
      961 gtggacctat attcagcaga aaaatccaga agtctttcag gctattcgta agaccatgtt
     1021 gagccgtttg accaaacatt ctgtcttgcc agatcgcaaa ctgtccaatg tcgtctatca
     1081 aatcaccaaa tctgtttatg gatttaatta atataagtgt tttataagag ggatttaaga
     1141 aaaattttaa ctttttctta gtccttttta atttcaggag attatactag agtcatcaaa
     1201 taaagaaaga ctctaaggag aatcctatga aattcaatcc aaatcaaaga tatactcgtt
     1261 ggtctattcg ccgtctcagt gtcggtgttg cctcagttgt tgtggctagt ggcttctttg
     1321 tcctagttgg tcagccaagt tctgtacgtg ccgatgtggt caatccgacc ccaggtcaag
     1381 tcttacctga agagacatcg ggaacgaaag agggtgactt atcagaaaaa ccaggagaca
     1441 ccgttctcac tcaagcgaaa cctgagggcg ttactggaaa tacgaattca cttccgacac
     1501 ctacagaaag aactgaagtg agcgaggaaa caaactcttc tagtctggat acactttttg
     1561 aaaaagatga agaagctcaa aaaaatccag agctaacaga tgtcttaaaa gaaactgtag
     1621 atacagctga tgtggatggg acacaagcaa gtctagcaga aactactcct gaacaagtaa
     1681 aaggtggagt gaaagaaaat acaaaagaca gcatcgatgt tcctgctgct tatcttgaaa
     1741 aagctgaagg gaaaggtcct ttcactgccg gtgtaaacca agtaattcct tatgaactat
     1801 tcgctggtga tggtatgtta actcgtctat tactaaaagc ttcggataat gctccttggt
     1861 ctgacaatgg tactgctaaa aatcctgctt tacctcctct tgaaggatta acaaaaggga
     1921 aatacttcta tgaagtagac ttaaatggca atactgttgg taaacaaggt caagctttaa
     1981 ttgatcaact tcgcgctaat ggtactcaaa cttataaagc tactgttaaa gtttacggaa
     2041 ataaagacgg taaagctgac ttgactaatc tagttgctac taaaaatgta gacatcaaca
     2101 tcaatggatt agttgctaaa gaaactgtcg aaaaagctgt taaagataac gttaaaga
//
LOCUS       DBEJHE010000073         1911 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC4 isolate 671759
            SAMN38261586-rid24793303.denovo.73, whole genome shotgun sequence.
ACCESSION   DBEJHE010000073 DBEJHE010000000
VERSION     DBEJHE010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261586
            Sequence Read Archive: SRR26833752
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1911)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1911)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576136.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576136.1
            Genome Coverage       :: 109x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 19:48:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,067
            CDSs (total)                      :: 2,029
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 131
            CDSs (without protein)            :: 131
            Pseudo Genes (ambiguous residues) :: 0 of 131
            Pseudo Genes (frameshifted)       :: 64 of 131
            Pseudo Genes (incomplete)         :: 59 of 131
            Pseudo Genes (internal stop)      :: 46 of 131
            Pseudo Genes (multiple problems)  :: 32 of 131
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1911
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261586-rid24793303.denovo.73"
                     /strain="GPSC4"
                     /isolate="671759"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(52..234)
                     /locus_tag="ACL3EZ_002047"
     CDS             complement(52..234)
                     /locus_tag="ACL3EZ_002047"
                     /inference="COORDINATES: protein motif:HMM:NF016232.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGR0393550.1"
                     /translation="MDLKFEGVDLEYKKAKNNLPESFWETYSAFANTNGGKIILGIDE
                     KNIDTYQRVNRLPAKL"
     gene            525..>1911
                     /gene="pcpA"
                     /locus_tag="ACL3EZ_002048"
     CDS             525..>1911
                     /gene="pcpA"
                     /locus_tag="ACL3EZ_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein PcpA"
                     /protein_id="HGR0393551.1"
                     /translation="MKKTTILSLTTAAVILAAYVPNEPILADTPSSEVIKETKVGSII
                     QQNNIKYKVLTVEGNIGTVQVGNGVTPVEFEAGQDGKPFTIPTKITVGDKVFTVTEVA
                     SQAFSYYPDETGRIVYYPSSITIPSSIKKIQKKGFHGSKAKTIIFDKGSQLEKIEDRA
                     FDFSELEEIELPASLEYIGTSAFSFSQKLKKLTFSSSSKLELISHEAFANLSNLEKLT
                     LPKSVKTLGSNLFRLTTSLKHVDVEEGNESFASVDGVLFSKDKTQLIYYPSQKNDESY
                     KTPKETKELASYSFNKNSYLKKLELNEGLEKIGTFAFADAIKLEEISLPNSLETIERL
                     AFYGNLELKELILPDNVKNFGKHVMNGLPKLKSLTIGNNINSLPSFFLSGVLDSLKEI
                     HIKNKSTEFSVKKDTFAIPETVKFYVTSEHIKDVLKSNLSTSNDIIVEKVDNIKQETD
                     VAKPKKNSNRGV"
BASE COUNT          700 a          270 c          301 g          640 t
ORIGIN      
        1 tgaacaccaa caagacgctt aaatcgtgta tcagttaatt gtttacttgc ttcataattt
       61 cgcagggagt ctattgactc tttggtaggt gtcaatgttt ttttcatcta tcccgagaat
      121 tattttcccg ccatttgtat ttgcaaatgc tgagtaggtt tcccagaaag actctggaag
      181 attgttttta gcttttttgt attctaaatc aaccccttca aattttaagt ccatattttt
      241 cctttacatc tgttttttgt ggttctggta tttgttcaag ttgagtgata atatagcgaa
      301 ttgaatttcg agagttttta ctcagttaat ttctttttta acccacttta attttccttg
      361 acttaaaatt taaaaatgat atactgtgtt tatggagaga tgacaattta taaaatgtac
      421 tactctattc tactagataa tgattgaata aaacttttta taacaacggc tagcaaagtt
      481 ataattttat atctattaga aaataaatat gtaaggaaat ttaaatgaaa aaaactacaa
      541 tattatcatt aactacagct gcggttattt tagcagcata tgtccctaat gaaccaatcc
      601 tagcagatac tcctagttcg gaagtaatca aagagactaa agttggaagt attattcaac
      661 aaaataatat caaatataag gttctaactg tagaaggtaa cataggaact gttcaagtgg
      721 gtaatggagt tactcctgta gagtttgaag ctggtcaaga tggaaaacca ttcacgattc
      781 ctacaaaaat cacagtaggt gataaagtat ttaccgttac tgaagtagct agtcaagctt
      841 ttagttatta tccagatgaa acaggtagaa ttgtctacta tcctagctct attactatcc
      901 catcaagcat aaaaaaaata caaaaaaaag gcttccatgg aagtaaagct aaaactatta
      961 tttttgacaa aggcagtcag ctggagaaaa ttgaagatag agcttttgat ttttctgaat
     1021 tagaagagat tgaattgcct gcatctctag aatatattgg aacaagtgca ttttctttta
     1081 gtcaaaaatt gaaaaagcta accttttcct caagttcaaa attagaatta atatcacatg
     1141 aggcttttgc taatttatca aatttagaga aactaacatt accaaaatcg gttaaaacat
     1201 taggaagtaa tctatttaga ctcactacta gcttaaaaca tgttgatgtt gaagaaggaa
     1261 atgaatcgtt tgcctcagtt gatggtgttt tgttttcaaa agataaaact caattaattt
     1321 attatccaag tcaaaaaaat gacgaaagtt ataaaacgcc taaagagaca aaagaacttg
     1381 catcatattc gtttaataaa aattcttact tgaaaaaact cgaattgaat gaaggtttag
     1441 aaaaaatcgg tacttttgca tttgcggatg cgattaaact tgaagaaatt agcttaccaa
     1501 atagtttaga aactattgaa cgtttagcct tttacggtaa tttagaatta aaagaactta
     1561 tattaccaga taatgttaaa aattttggta aacacgttat gaacggttta ccaaaattaa
     1621 aaagtttaac aattggtaat aatatcaact cattgccgtc cttcttccta agtggcgtct
     1681 tagattcatt aaaggaaatt catattaaga ataaaagtac agagttttct gtgaaaaaag
     1741 atacatttgc aattcctgaa actgttaagt tctatgtaac atcagaacat ataaaagatg
     1801 ttcttaaatc aaatttatct actagtaatg atatcattgt tgaaaaagta gataatataa
     1861 aacaagaaac tgatgtagct aaacctaaaa agaattctaa tcggggagta g
//
LOCUS       DBEJHE010000074         1661 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC4 isolate 671759
            SAMN38261586-rid24793303.denovo.74, whole genome shotgun sequence.
ACCESSION   DBEJHE010000074 DBEJHE010000000
VERSION     DBEJHE010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261586
            Sequence Read Archive: SRR26833752
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1661)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1661)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576136.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576136.1
            Genome Coverage       :: 109x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 19:48:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,067
            CDSs (total)                      :: 2,029
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 131
            CDSs (without protein)            :: 131
            Pseudo Genes (ambiguous residues) :: 0 of 131
            Pseudo Genes (frameshifted)       :: 64 of 131
            Pseudo Genes (incomplete)         :: 59 of 131
            Pseudo Genes (internal stop)      :: 46 of 131
            Pseudo Genes (multiple problems)  :: 32 of 131
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1661
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261586-rid24793303.denovo.74"
                     /strain="GPSC4"
                     /isolate="671759"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            145..1491
                     /locus_tag="ACL3EZ_002049"
     CDS             145..1491
                     /locus_tag="ACL3EZ_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380-like element ISSpn5 family transposase"
                     /protein_id="HGR0393552.1"
                     /translation="MNSLPNHHFQNKSFYQLSFDGGHLTQYGGLIFFQELFSQLKLKE
                     RISKYLVTNDQRRYCRYSDSDILVQFLFQLLTGYGTDYACKELSADAYFPKLLEGGQL
                     ASQPTLSRFLSRTDEETVHSLRCLNLELVEFFLQFHQLNQLIVDIDSTHFTTYGKQEG
                     VAYNAHYRAHGYHPLYAFEGKTGYCFNAQLRPGNRYCSEEADSFITPVLERFNQLLFR
                     MDSGFATPKLYDLIEKTGQYYLIKLKKNTVLSRLGDLSLPCPQDEDLTILPHSAYSET
                     LYQAGSWSHKRRVCQFSERKEGNLFYDVISLVTNMTSGTSQDQFQLYRGRGQAENFIK
                     EMKEGFFGDKTDSSTLIKNEVRMMMSCIAYNLYLFLKHLAGGDFQTLTIKRFRHLFLH
                     VVGKCVRTGRKQLLKLSSLYAYSELFSALYSRIRKVNLNLPVPYEPPRRKASLMMH"
BASE COUNT          491 a          358 c          325 g          487 t
ORIGIN      
        1 ctaaaaacca tccagaatcc ttgccttagc ttagatcctg gatggtttct tttttcaccc
       61 aatgggtgtt ttttactaga caaaaaagag tttccccttt atggtataag tgtagaaaaa
      121 aacacaaaaa gaaaggaaac tcacatgaac agtttaccaa atcatcactt ccaaaacaag
      181 tctttttacc aactatcttt cgatggaggt catttaaccc agtatggtgg tcttatcttt
      241 tttcaggaac ttttttccca gctgaaacta aaagagcgga tttctaagta tttagtaacg
      301 aatgaccaac gccgctactg tcgttattcg gattcagata tccttgtcca gttcctcttt
      361 caactgttaa caggttatgg aacggactat gcttgtaaag aattgtcagc tgatgcctac
      421 tttccaaaat tattggaagg agggcagctt gcttcacagc caaccttatc ccgttttctt
      481 tccagaactg acgaggaaac agtccatagt ttgcgatgcc tcaaccttga attggtcgaa
      541 ttctttttac agtttcacca gctaaaccaa ctcattgtag atatcgattc tacccatttc
      601 acaacttatg gcaagcaaga aggtgttgct tataacgccc actatcgtgc tcatggctat
      661 catcctcttt atgctttcga ggggaagaca ggttattgtt tcaatgccca gcttcgtcct
      721 ggtaatcgtt attgttctga agaggcagac agctttatca cacctgtttt agaacggttt
      781 aatcaacttc tctttcgaat ggatagtggc tttgcgaccc caaaattata cgatttaatt
      841 gaaaaaacag ggcaatacta cctcataaaa ctcaagaaaa atactgttct gagccgtctt
      901 ggagaccttt ccctcccttg tccacaggat gaggacttaa ccatcttgcc ccactccgcc
      961 tactcagaaa ctctctatca agcaggatct tggtcgcaca agcgtcgtgt ctgccagttc
     1021 tctgaacgaa aagaaggaaa cttgttctac gatgttattt ctctcgttac aaatatgacg
     1081 agtggaacaa gccaagacca gtttcagctt tatcgtggac gtggtcaagc cgagaatttc
     1141 atcaaggaga tgaaggaggg attttttggc gataaaacgg atagttcaac cttaatcaaa
     1201 aacgaagttc gtatgatgat gagctgtatc gcctacaatc tctatctttt tctcaaacat
     1261 ctagctggag gtgacttcca aactttaaca atcaaacgct tccgccatct ttttcttcac
     1321 gtggtaggaa aatgtgttcg aacaggacgc aagcagctcc tcaaattgtc tagtctctat
     1381 gcctattccg aattgttttc agcactttat tctaggatta gaaaagtcaa cctgaatctt
     1441 cctgttcctt atgaaccacc tagaagaaaa gcgtcgttaa tgatgcatta aagaacagtc
     1501 gagatgaaaa aatcgtgtga cgaaccaagg gaggagtctg cccttttgag gaaatctagc
     1561 gaggaaaaac gatactggaa cagcagaaag taaaactgac ctcatgagga ggaagaaagt
     1621 ggctcatgag gtcaggggtt ttgtaagtta catctagttg a
//
LOCUS       DBEJHE010000075         1423 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC4 isolate 671759
            SAMN38261586-rid24793303.denovo.75, whole genome shotgun sequence.
ACCESSION   DBEJHE010000075 DBEJHE010000000
VERSION     DBEJHE010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261586
            Sequence Read Archive: SRR26833752
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1423)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1423)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576136.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576136.1
            Genome Coverage       :: 109x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 19:48:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,067
            CDSs (total)                      :: 2,029
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 131
            CDSs (without protein)            :: 131
            Pseudo Genes (ambiguous residues) :: 0 of 131
            Pseudo Genes (frameshifted)       :: 64 of 131
            Pseudo Genes (incomplete)         :: 59 of 131
            Pseudo Genes (internal stop)      :: 46 of 131
            Pseudo Genes (multiple problems)  :: 32 of 131
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1423
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261586-rid24793303.denovo.75"
                     /strain="GPSC4"
                     /isolate="671759"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            <1..>1423
                     /locus_tag="ACL3EZ_002050"
     CDS             <1..>1423
                     /locus_tag="ACL3EZ_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HGR0393553.1"
                     /translation="SRTARGVAVPHGNHYHFIPYEQMSELEKRIARIIPLRYRSNHWV
                     PDSRPEQPSPQSTPEPSPSLQPAPNPQPAPSNPIDEKLVKEAVRKVGDGYVFEENGVS
                     RYIPAKDLSAETAAGIDSKLAKQESLSHKLGAKKTDLPSSDREFYNKTYDLLARIHQD
                     LLDNKGRQVDFEALDNLLERLKDVSSDKVKLVDDILAFLAPIRHPERLGKPNAQITYT
                     DDEIQVAKLAGKYTTEDGYIFDPRDITSDEGDAYVTPHMTHSHWIKKDSLSEAERAAA
                     QAYAKEKGLTPPSTDHQDSGNTEAKGAEAIYNRVKAAKKVPLDRMPYNLQYTVEVKNG
                     SLIIPHYDHYHNIKFEWFDEGLYEAPKGYTLEDLLATVKYYVEHPNERPHSDNGFGNA
                     SDHVRKNKADQDSKPDEDKGHDEVSEPTHPESDEKENHAGLNPSADNLYKPSTDTEET
                     EEEAEDTTDEAEIPQVEHSVINA"
BASE COUNT          474 a          295 c          304 g          350 t
ORIGIN      
        1 caagtcgaac cgccagaggt gtagctgtcc ctcatggtaa ccattaccac tttatccctt
       61 atgaacaaat gtctgaattg gaaaaacgaa ttgctcgtat tattcccctt cgttatcgtt
      121 caaaccattg ggtaccagat tcaagaccag aacaaccaag tccacaatcg actccggaac
      181 ctagtccaag tctgcaacct gcaccaaatc ctcaaccagc tccaagcaat ccaattgatg
      241 agaaattggt caaagaagct gttcgaaaag taggcgatgg ttatgtcttt gaggagaatg
      301 gagtttctcg ttatatccca gccaaggatc tttcagcaga aacagcagca ggcattgata
      361 gcaaactggc caagcaggaa agtttatcgc ataagctagg agctaagaaa actgacctcc
      421 catctagtga tagagaattt tacaataaga cttatgactt actagcaaga attcaccaag
      481 atttacttga taataaaggt cgacaagttg attttgaggc tttggataac ctgttggaac
      541 gactcaagga tgtctcaagt gataaagtca agttagtgga tgatattctt gccttcttag
      601 ctccgattcg tcatccagaa cgtttaggaa aaccaaatgc gcaaattacc tacactgatg
      661 atgagattca agtagccaag ttggcaggca agtacacaac agaagacggt tatatctttg
      721 atcctcgtga tataaccagt gatgaggggg atgcctatgt aactccacat atgacccata
      781 gccactggat taaaaaagat agtttgtctg aagctgagag agcggcagcc caggcttatg
      841 ctaaagagaa aggtttgacc cctccttcga cagaccatca ggattcagga aatactgagg
      901 caaaaggagc agaagctatc tacaaccgcg tgaaagcagc taagaaggtg ccacttgatc
      961 gtatgcctta caatcttcaa tatactgtag aagtcaaaaa cggtagttta atcatacctc
     1021 attatgacca ttaccataac atcaaatttg agtggtttga cgaaggcctt tatgaggcac
     1081 ctaaggggta tactcttgag gatcttttgg cgactgtcaa gtactatgtc gaacatccaa
     1141 acgaacgtcc gcattcagat aatggttttg gtaacgctag cgaccatgtt cgtaaaaata
     1201 aggcagacca agacagtaaa cctgatgaag ataagggaca tgatgaagta agtgagccaa
     1261 ctcaccctga atctgatgaa aaagagaatc acgctggttt aaatccttca gcagataatc
     1321 tttataaacc aagcactgat acggaagaga cagaggaaga agctgaagat actacagatg
     1381 aggctgaaat tcctcaagta gagcattctg ttattaacgc taa
//
LOCUS       DBEJHE010000076         1088 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC4 isolate 671759
            SAMN38261586-rid24793303.denovo.76, whole genome shotgun sequence.
ACCESSION   DBEJHE010000076 DBEJHE010000000
VERSION     DBEJHE010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261586
            Sequence Read Archive: SRR26833752
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1088)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1088)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576136.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576136.1
            Genome Coverage       :: 109x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 19:48:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,067
            CDSs (total)                      :: 2,029
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 131
            CDSs (without protein)            :: 131
            Pseudo Genes (ambiguous residues) :: 0 of 131
            Pseudo Genes (frameshifted)       :: 64 of 131
            Pseudo Genes (incomplete)         :: 59 of 131
            Pseudo Genes (internal stop)      :: 46 of 131
            Pseudo Genes (multiple problems)  :: 32 of 131
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1088
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261586-rid24793303.denovo.76"
                     /strain="GPSC4"
                     /isolate="671759"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(493..891)
                     /locus_tag="ACL3EZ_002051"
     CDS             complement(493..891)
                     /locus_tag="ACL3EZ_002051"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR0393554.1"
                     /translation="MENKESHKSQEIGNLIRVYNRSKREEAESEPLNLYVEDEKGNLL
                     AGLIAETFGNWLEIEYLFVKEELRGQGIGSKLLQQAESEAKNRNCCFAFVNTYQFQAP
                     DFYQKHGYKEVFSLQDYLYIRQRYYYQKNL"
BASE COUNT          330 a          209 c          166 g          383 t
ORIGIN      
        1 gctatcgatt gtcaaatgtt tggcttttgt agtataattg tcttgcatct ctgtgccttt
       61 cttgtgtttg tggttgaaca acaagtataa cacagaggtg ttttcttatg cctacaagag
      121 ctttcattat ttccattttc ttttggattt cactctattc tgaaaaactt gtgtatattt
      181 actgaagcta gcaagtctta cctgtaaatt taatgaaagc aacacaaaat ccgagagggg
      241 aatctcggat taatagatag agagttttta gtttaaataa attgtttaaa atatcaacaa
      301 catcacttct tttcttaacc tgataagtct tgattcctaa ttttggggct acgattatat
      361 tgtcctcaat atcgtctaga aagacacaat ttctaggtta taactggtat ttatcgatag
      421 ttactcatat acatcagtcc acctccatac ttatgtgcga gcctctcttt gtattatacc
      481 tccatactca ccttacagat tcttttggta ataatatctt tgcctaatgt agagatagtc
      541 ttgcaaagaa aaaacttcct tgtagccatg tttctgataa aagtccggtg cctggaactg
      601 gtaagtattg acaaaggcaa aacaacaatt tcgattctta gcttcacttt ctgcctgttg
      661 caatagtttt gaaccgattc cttgccctcg cagttcctct tttacaaaca aatactcgat
      721 ttctagccaa tttccaaaag tctctgctat caaacctgcc aggagattgc ccttttcatc
      781 ttcgacataa agattaagtg gctcactttc agcctcttct ctttttgaac ggttataaac
      841 acgaatcaga ttccctattt cttgcgattt atgtgattcc ttattttcca atctaaagta
      901 tagtgaaatg aaataaaaca tgcgcaaatc gattaaggaa tttaatctaa tttctaacaa
      961 tgtcttagaa atcaaagtgt actattttaa cttcaatgca ctatacatct aatactcaat
     1021 aaaaatcaaa gagcaaacta ggaaactagc cgcaggttgc tcaaaacact gttttgaggt
     1081 tgtagata
//
LOCUS       DBEJHE010000077          957 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC4 isolate 671759
            SAMN38261586-rid24793303.denovo.77, whole genome shotgun sequence.
ACCESSION   DBEJHE010000077 DBEJHE010000000
VERSION     DBEJHE010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261586
            Sequence Read Archive: SRR26833752
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 957)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 957)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576136.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576136.1
            Genome Coverage       :: 109x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 19:48:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,067
            CDSs (total)                      :: 2,029
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 131
            CDSs (without protein)            :: 131
            Pseudo Genes (ambiguous residues) :: 0 of 131
            Pseudo Genes (frameshifted)       :: 64 of 131
            Pseudo Genes (incomplete)         :: 59 of 131
            Pseudo Genes (internal stop)      :: 46 of 131
            Pseudo Genes (multiple problems)  :: 32 of 131
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..957
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261586-rid24793303.denovo.77"
                     /strain="GPSC4"
                     /isolate="671759"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(8..81)
                     /locus_tag="ACL3EZ_002052"
     tRNA            complement(8..81)
                     /locus_tag="ACL3EZ_002052"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(45..47),aa:Ile,seq:cat)
     gene            complement(95..168)
                     /locus_tag="ACL3EZ_002053"
     tRNA            complement(95..168)
                     /locus_tag="ACL3EZ_002053"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(132..134),aa:Met,seq:cat)
     gene            complement(174..247)
                     /locus_tag="ACL3EZ_002054"
     tRNA            complement(174..247)
                     /locus_tag="ACL3EZ_002054"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(211..213),aa:Pro,seq:tgg)
     gene            complement(263..336)
                     /locus_tag="ACL3EZ_002055"
     tRNA            complement(263..336)
                     /locus_tag="ACL3EZ_002055"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(300..302),aa:Arg,seq:acg)
     gene            complement(346..431)
                     /locus_tag="ACL3EZ_002056"
     tRNA            complement(346..431)
                     /locus_tag="ACL3EZ_002056"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(395..397),aa:Leu,seq:taa)
     gene            complement(439..510)
                     /locus_tag="ACL3EZ_002057"
     tRNA            complement(439..510)
                     /locus_tag="ACL3EZ_002057"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(476..478),aa:Gly,seq:gcc)
     gene            complement(533..605)
                     /locus_tag="ACL3EZ_002058"
     tRNA            complement(533..605)
                     /locus_tag="ACL3EZ_002058"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(570..572),aa:Thr,seq:tgt)
     gene            complement(624..705)
                     /locus_tag="ACL3EZ_002059"
     tRNA            complement(624..705)
                     /locus_tag="ACL3EZ_002059"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(669..671),aa:Leu,seq:tag)
     gene            complement(711..783)
                     /locus_tag="ACL3EZ_002060"
     tRNA            complement(711..783)
                     /locus_tag="ACL3EZ_002060"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(748..750),aa:Lys,seq:ttt)
     gene            complement(808..880)
                     /locus_tag="ACL3EZ_002061"
     tRNA            complement(808..880)
                     /locus_tag="ACL3EZ_002061"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(845..847),aa:Asp,seq:gtc)
     gene            complement(883..955)
                     /locus_tag="ACL3EZ_002062"
     tRNA            complement(883..955)
                     /locus_tag="ACL3EZ_002062"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(920..922),aa:Val,seq:tac)
BASE COUNT          249 a          279 c          218 g          211 t
ORIGIN      
        1 attcaaatgg accttgtagg acttgaacct acgaccactc ggttatgagc cgagagctct
       61 aaccagctga gctaaaggtc cgacaagatc attatagcgg cgaaggggat cgaacccccg
      121 acctcccggg tatgaaccgg acgctctagc cagctgagct acaccgccat gaatcgggaa
      181 gacaggattc gaacctgcga caccttggtc ccaaaccaag tactctacca agctgagcta
      241 cttcccgagt taaatagaaa aatgcaccct agaggagtcg aacctctaac cgcctgattc
      301 gtagtcaggt actctatcca gttgagctaa gggtgctcca tattatgccg aggaccggaa
      361 tcgaaccggt acgatcgtta ccaatcgcag gattttaagt cctgtgcgtc tgccagttcc
      421 gccaccccgg cctctctaag cgaacgacgg gattcgaacc cgcgaccccc accttggcaa
      481 ggtggtgttc taccactgaa ctacgttcgc actgttttct tctatctaaa aatgccggct
      541 acatgacttg aacacgcgac cctctgatta caaatcagat gctctaccaa ctgagctaag
      601 ccggctcatt tgttatatct taatgcgggt taagggactt gaacccccac gccgttaagc
      661 gccagatcct aaatctggtg cgtctgccaa ttccgccaaa cccgcatata tgacccgtac
      721 tgggctcgaa ccagtgaccc attgattaaa agtcaattgc tctaccaact gagctaacga
      781 gtctaaaata acttgcgtta ccttaaacgg tcccgacggg aatcgaaccc gcgatcttcg
      841 ccgtgacagg gcgacgtgat aaccgctaca ctacgggacc tttgggagtt aacgggatcg
      901 aaccgctgac cctctgcttg taaggcagat gctctcccag ctgagctaaa ctcccta
//
LOCUS       DBEJHE010000078          561 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC4 isolate 671759
            SAMN38261586-rid24793303.denovo.78, whole genome shotgun sequence.
ACCESSION   DBEJHE010000078 DBEJHE010000000
VERSION     DBEJHE010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261586
            Sequence Read Archive: SRR26833752
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 561)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 561)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576136.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576136.1
            Genome Coverage       :: 109x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 19:48:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,067
            CDSs (total)                      :: 2,029
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 131
            CDSs (without protein)            :: 131
            Pseudo Genes (ambiguous residues) :: 0 of 131
            Pseudo Genes (frameshifted)       :: 64 of 131
            Pseudo Genes (incomplete)         :: 59 of 131
            Pseudo Genes (internal stop)      :: 46 of 131
            Pseudo Genes (multiple problems)  :: 32 of 131
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..561
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261586-rid24793303.denovo.78"
                     /strain="GPSC4"
                     /isolate="671759"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(<1..139)
                     /locus_tag="ACL3EZ_002063"
     CDS             complement(<1..139)
                     /locus_tag="ACL3EZ_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HGR0393555.1"
                     /translation="MKSTEEEIQTIKTLLKDFRTAKYHKRLQIVLFRLMGKSYKEIID
                     LL"
BASE COUNT          185 a           87 c           88 g          201 t
ORIGIN      
        1 ctaaaagatc tataatctct ttataagatt tgcccatcag acgaaataga acgatttgaa
       61 ggcgtttatg atatttagct gtacgaaagt cttttaaaag tgttttgatg gtttggattt
      121 cttcttcagt tgatttcata ttactattgt ataatgcttt ttgatttgag tctagtatta
      181 tactcttcga aaatctcttc aaaccgcgtc agcttcgcct tgtcgtatag atgttactga
      241 cttcgtcagt tctatctaca acctaaaaac agtgttttga gcagtctgca gctaactttc
      301 tataacaaaa tgaaataaga acaagacaaa tcaatcaaga caatcaaatc gatttctaac
      361 aatgttttag aagtagatgt gtactattct agtttcaata tattatagtt tgctctttga
      421 ttttcattga gtattagttc aatatctaaa aaaagaggct ctataatatt tgtagtgggt
      481 aaatccccta tagatattat ggagcctatt tttgtgtaga aaaaaagtcc catatgacct
      541 ataatgaaaa gcgacaaaac c
//
LOCUS       DBEJHE010000079          476 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC4 isolate 671759
            SAMN38261586-rid24793303.denovo.79, whole genome shotgun sequence.
ACCESSION   DBEJHE010000079 DBEJHE010000000
VERSION     DBEJHE010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261586
            Sequence Read Archive: SRR26833752
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 476)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576136.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576136.1
            Genome Coverage       :: 109x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 19:48:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,067
            CDSs (total)                      :: 2,029
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 131
            CDSs (without protein)            :: 131
            Pseudo Genes (ambiguous residues) :: 0 of 131
            Pseudo Genes (frameshifted)       :: 64 of 131
            Pseudo Genes (incomplete)         :: 59 of 131
            Pseudo Genes (internal stop)      :: 46 of 131
            Pseudo Genes (multiple problems)  :: 32 of 131
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261586-rid24793303.denovo.79"
                     /strain="GPSC4"
                     /isolate="671759"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(188..275)
                     /locus_tag="ACL3EZ_002064"
     tRNA            complement(188..275)
                     /locus_tag="ACL3EZ_002064"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(239..241),aa:Ser,seq:gct)
     gene            complement(282..355)
                     /locus_tag="ACL3EZ_002065"
     tRNA            complement(282..355)
                     /locus_tag="ACL3EZ_002065"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(319..321),aa:Ile,seq:gat)
     gene            complement(391..461)
                     /locus_tag="ACL3EZ_002066"
     tRNA            complement(391..461)
                     /locus_tag="ACL3EZ_002066"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(427..429),aa:Gly,seq:tcc)
BASE COUNT          158 a          115 c           85 g          118 t
ORIGIN      
        1 aactttgaaa acttcaaaaa acggattttc atcgctctga acatcaaaaa agaaaggacg
       61 aaatttgtcc tttctcgagc ttagcttttc ttcaacccac tacagttgac aaagagcctt
      121 aagtttacgg atctgaagtt ttattgtctc taaaaacaaa aaagagagtt acaaactctc
      181 attaaaacgg agaataaggg attcgaaccc ttgcgccagt tacccgacct aacgatttag
      241 caaaccgtcc tcttcagcct cttgagtaat tctccaatta atgggcacga gtggactcga
      301 accaccgacc tcacgcttat caggcgtgcg ctctaaccac ctgagctacg cgcccaagtt
      361 aaaaaacttg gtaatttgaa caaagttcaa agcgggtgac gagaatcgaa ctcgcgacaa
      421 cagcttggaa ggctgtagtt ttaccactaa actacacccg cataaatact atcaat
//
LOCUS       DBEJHE010000080          450 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC4 isolate 671759
            SAMN38261586-rid24793303.denovo.80, whole genome shotgun sequence.
ACCESSION   DBEJHE010000080 DBEJHE010000000
VERSION     DBEJHE010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261586
            Sequence Read Archive: SRR26833752
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 450)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 450)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576136.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576136.1
            Genome Coverage       :: 109x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 19:48:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,067
            CDSs (total)                      :: 2,029
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 131
            CDSs (without protein)            :: 131
            Pseudo Genes (ambiguous residues) :: 0 of 131
            Pseudo Genes (frameshifted)       :: 64 of 131
            Pseudo Genes (incomplete)         :: 59 of 131
            Pseudo Genes (internal stop)      :: 46 of 131
            Pseudo Genes (multiple problems)  :: 32 of 131
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..450
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261586-rid24793303.denovo.80"
                     /strain="GPSC4"
                     /isolate="671759"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            <1..>450
                     /locus_tag="ACL3EZ_002067"
     CDS             <1..>450
                     /locus_tag="ACL3EZ_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HGR0393556.1"
                     /translation="FSTLVEIVRGGSPRPIKDYLTSEVDGINWIKIGDTEKGEKYINN
                     VKEKIKKSGLNKTRFVKKGTFLLTNSMSFGRPYILNVDGAIHDGWLAISNYENSLNKD
                     YLFYILSSNVVYSQFLSLISGAVVKNLNSDKVASILIPLPPLSEQQRI"
BASE COUNT          159 a           66 c           74 g          151 t
ORIGIN      
        1 ttttctacat tggttgaaat tgtcagaggt ggctctccac gaccaatcaa agattatctt
       61 acttctgaag tagatggaat aaattggata aaaataggtg atactgaaaa gggtgaaaag
      121 tatataaata atgttaaaga aaaaatcaaa aaatcagggc ttaacaaaac tagatttgta
      181 aaaaaaggta catttttgtt aactaattct atgagttttg gtagacctta tattttgaat
      241 gttgatggtg caatacacga tggatggttg gctatttcga actatgaaaa ctcattaaat
      301 aaagattacc tattctatat tctttcatca aatgtagttt attctcaatt tctatctcta
      361 attagtggag ctgttgtgaa aaacttgaat agtgataaag ttgcttctat tcttatccct
      421 ctccccccac tatccgaaca acaacgcata
//
